FedInvent™ Patents

Patent Details for Tuesday, April 28, 2020 

This page was updated on Monday, March 27, 2023 at 06:04 AM GMT

Department of Health and Human Services (HHS) 

US 10631730 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) David Huang (Portland, Oregon);  Yali Jia (Portland, Oregon);  Miao Zhang (Portland, Oregon)
ABSTRACT Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
FILED Monday, February 04, 2019
APPL NO 16/266545
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/0025 (20130101)
A61B 3/102 (20130101)
A61B 3/1241 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/20182 (20130101)
G06T 2207/30041 (20130101)
G06T 2207/30104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631775 Thelen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Darryl Gerard Thelen (Madison, Wisconsin);  Jack Anthony Martin (Madison, Wisconsin);  Matt S. Allen (Middleton, Wisconsin);  Daniel Joseph Segalman (East Lansing, Michigan);  Laura Ann Slane (Penfield, New York)
ABSTRACT Axial stress or similar properties in a stressed tendon or ligament are measured by mechanical excitation of a shear wave in the tendon or ligament measured using ultrasonic displacement techniques at least two different longitudinal positions to derive a shear wave propagation speed. This shear wave propagation speed may be equated to an axial stress on the tissue using a model. Rapidly repeated measurements allow dynamic axial stress measurements to be obtained for clinical study.
FILED Friday, August 28, 2015
APPL NO 14/839448
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0053 (20130101)
A61B 5/4519 (20130101) Original (OR) Class
A61B 5/4523 (20130101)
A61B 5/4533 (20130101)
A61B 8/485 (20130101)
A61B 8/4494 (20130101)
A61B 8/5207 (20130101)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631792 Pinsky
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HGIHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Michael R. Pinsky (Pittsburgh, Pennsylvania)
ABSTRACT A system and method for determining a patient's susceptibility to develop cardiorespiratory instability wherein physiological parameters are analyzed with respect to a dynamics systems model to produce and indicator associated with a probability that the patient will become unstable is provided.
FILED Friday, December 20, 2013
APPL NO 14/137576
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0022 (20130101)
A61B 5/029 (20130101)
A61B 5/742 (20130101)
A61B 5/02028 (20130101)
A61B 5/02055 (20130101)
A61B 5/02108 (20130101)
A61B 5/02405 (20130101)
A61B 5/7275 (20130101) Original (OR) Class
A61B 5/7475 (20130101)
A61B 5/14539 (20130101)
A61B 5/14551 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631800 Siewerdsen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland);  Carestream Health, Inc. (Rochester, New York)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Carestream Health, Inc. (Rochester, New York)
INVENTOR(S) Jeffrey H. Siewerdsen (Baltimore, Maryland);  J. Webster Stayman (Baltimore, Maryland);  Wojciech Zbijewski (Baltimore, Maryland);  John Yorkston (Rochester, New York)
ABSTRACT The present invention is directed to a system and method for dual-energy (DE) or multiple-energy (spectral) cone-beam computed tomography (CBCT) using a configuration of multiple x-ray sources and a single detector. The x-ray sources are operated to produce x-ray spectra of different energies (peak kilovoltage (kVp) and/or filtration). Volumetric 3D image reconstruction and dual or triple energy 3D image decomposition can be executed using data from the CBCT scan. The invention allows for a variety of selections in energy and filtration associated with each source and the order of pulsing for each source (“firing pattern”). The motivation for distributing the sources along the z direction in CBCT includes extension of the longitudinal field of view and reduction of cone-beam artifacts.
FILED Tuesday, November 25, 2014
APPL NO 15/030818
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)
A61B 6/482 (20130101)
A61B 6/505 (20130101)
A61B 6/4007 (20130101) Original (OR) Class
A61B 6/4035 (20130101)
A61B 6/4085 (20130101)
A61B 6/5205 (20130101)
A61B 6/5235 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631877 Murphy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of AMerica, as represented by the Secretary of the Defense (Washington, District of Columbia)
INVENTOR(S) Ryan Murphy (Columbia, Maryland);  Ehsan Basafa (Baltimore, Maryland);  Mehran Armand (Fulton, Maryland);  Chad Gordon (Lutherville, Maryland);  Gerald Grant (Goshen, Kentucky);  Peter Liacouras (North Potomac, Maryland)
ABSTRACT Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating.
FILED Wednesday, November 26, 2014
APPL NO 15/100241
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/15 (20130101) Original (OR) Class
A61B 17/176 (20130101)
A61B 17/1695 (20130101)
A61B 17/1739 (20130101)
A61B 17/8085 (20130101)
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 2034/105 (20160201)
A61B 2034/108 (20160201)
A61B 2034/2051 (20160201)
A61B 2034/2055 (20160201)
A61B 2034/2065 (20160201)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2803 (20130101)

Electric Digital Data Processing
G06F 19/3481 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/50 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/26 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631936 Krishnaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Venkataramanan Krishnaswamy (Lebanon, New Hampshire);  Richard J. Barth, Jr. (Hanover, New Hampshire);  Keith D. Paulsen (Hanover, New Hampshire)
ABSTRACT A method for guiding resection of local tissue from a patient includes generating at least one image of the patient, automatically determining a plurality of surgical guidance cues indicating three-dimensional spatial properties associated with the local tissue, and generating a visualization of the surgical guidance cues relative to the surface. A system for generating surgical guidance cues for resection of a local tissue from a patient includes a location module for processing at least one image of the patient to determine three-dimensional spatial properties of the local tissue, and a surgical cue generator for generating the surgical guidance cues based upon the three-dimensional spatial properties. A patient-specific locator form for guiding resection of local tissue from a patient includes a locator form surface matching surface of the patient, and a plurality of features indicating a plurality of surgical guidance cues, respectively.
FILED Friday, June 10, 2016
APPL NO 15/735907
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/20 (20160201) Original (OR) Class
A61B 2017/008 (20130101)
A61B 2017/3405 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10631973 Linderman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Stephen Linderman (St. Louis, Missouri);  Guy Genin (St. Louis, Missouri);  Stavros Thomopoulos (Clayton, Missouri);  Kollbe Ahn (Santa Barbara, California);  Victor Mark Birman (Chesterfield, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Stephen Linderman (St. Louis, Missouri);  Guy Genin (St. Louis, Missouri);  Stavros Thomopoulos (Clayton, Missouri);  Kollbe Ahn (Santa Barbara, California);  Victor Mark Birman (Chesterfield, Missouri)
ABSTRACT Provided herein are compositions and methods for treating a subject with damaged tissue, such as an injury associated with a tissue to tissue (e.g., a connective tissue-to-connective tissue or tissue to bone) interface. One aspect provides an adhesive film or adhesive layer, optionally comprising a biomaterial, tissue growth factors, including CTGF/CCN2, or cells.
FILED Friday, March 10, 2017
APPL NO 15/455792
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1146 (20130101)
A61B 17/06166 (20130101)
A61B 2017/00884 (20130101)
A61B 2017/00951 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/08 (20130101) Original (OR) Class
A61F 2/28 (20130101)
A61F 2220/005 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 17/145 (20130101)
A61L 24/0005 (20130101)
A61L 24/0015 (20130101)
A61L 24/0031 (20130101)
A61L 2300/64 (20130101)
A61L 2300/414 (20130101)
A61L 2430/02 (20130101)
A61L 2430/06 (20130101)
A61L 2430/10 (20130101)
A61L 2430/24 (20130101)
A61L 2430/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632013 Prausnitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia);  EMORY UNIVERSITY (Atlanta, Georgia)
INVENTOR(S) Mark R. Prausnitz (Atlanta, Georgia);  Henry F. Edelhauser (Atlanta, Georgia);  Samirkumar Rajnikant Patel (Atlanta, Georgia)
ABSTRACT Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye.
FILED Tuesday, September 19, 2017
APPL NO 15/708779
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/0017 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101)
A61M 2037/0023 (20130101)
A61M 2210/0612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632070 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Liangfang Zhang (San Diego, California);  Che-Ming Jack Hu (San Diego, California);  Weiwei Gao (La Jolla, California);  Jonathan Coop (La Jolla, California)
ABSTRACT The present invention provides for compositions comprising a polymeric hydrogel impregnated with a toxin-absorbing or binding nanoparticle. The present invention also provides for the use of the above compositions for decreasing or neutralizing the effect of a toxin, or for treating or preventing an infection by a microbe that produces a toxin, in a subject. The exemplary toxin is a biological toxin such as a viral, bacterial, fungal, plant or animal toxin.
FILED Monday, September 24, 2018
APPL NO 16/139612
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101) Original (OR) Class
A61K 9/0019 (20130101)
A61K 9/1629 (20130101)
A61K 9/5068 (20130101)
A61K 9/5115 (20130101)
A61K 9/5153 (20130101)
A61K 9/5176 (20130101)
A61K 31/49 (20130101)
A61K 31/49 (20130101)
A61K 35/17 (20130101)
A61K 35/18 (20130101)
A61K 35/19 (20130101)
A61K 35/58 (20130101)
A61K 35/63 (20150115)
A61K 38/1709 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 26/008 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 2300/404 (20130101)
A61L 2400/12 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/473 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632072 Costa et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
APPLICANT(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut)
INVENTOR(S) Antonio Costa (Farmington, Connecticut);  Diane J. Burgess (Farmington, Connecticut)
ABSTRACT The present disclosure provides systems and methods for the continuous production of liposomes. An example method includes (a) mixing a solution of lipid and organic solvent from one or more containers to create an organic solvent-lipid solution, (b) providing the organic solvent-lipid solution to a first inlet of an injection port at a first flow rate, wherein the first inlet is in fluid communication with a first conduit, (c) providing an aqueous solution to a second inlet of the injection port at a second flow rate, wherein the second inlet is influid communication with a second conduit, wherein the first conduit is positioned concentrically within the second conduit at an outlet of the injection port, and wherein the first conduit extends through the outlet of the injection port, and (d) mixing the organic lipid solution and the aqueous solution to create a plurality of liposomes.
FILED Friday, March 18, 2016
APPL NO 15/557575
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1277 (20130101) Original (OR) Class

Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 3/0807 (20130101)
B01F 5/045 (20130101)
B01F 15/00149 (20130101)
B01F 2215/0032 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632080 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Clark Zhang (Sunnyvale, California);  Panagiotis Mastorakos (Charlottesville, Virginia);  Jung Soo Suk (Baltimore, Maryland);  Justin Hanes (Baltimore, Maryland)
ABSTRACT Improved distribution can be achieved by delivering nanoparticles possessing non-adhesive surfaces via CED in a hyperosmolar infusate solution. This delivery strategy minimizes the hindrances imposed by the brain extracellular matrix and reduces the concentration of therapeutic that is confined within perivascular spaces.
FILED Friday, September 09, 2016
APPL NO 15/759465
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0085 (20130101)
A61K 9/5115 (20130101)
A61K 9/5123 (20130101)
A61K 9/5138 (20130101)
A61K 9/5146 (20130101)
A61K 9/5153 (20130101) Original (OR) Class
A61K 47/02 (20130101)
A61K 49/0032 (20130101)
A61K 49/0093 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632088 Silverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Richard B. Silverman (Winnetka, Illinois);  Hoang V. Le (Oxford, Mississippi);  Rima L. McLeod (Chicago, Illinois);  Dustin D. Hawker (Evanston, Illinois)
ABSTRACT Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human γ-aminobutyric aminotransferase (GABA-AT).
FILED Tuesday, October 10, 2017
APPL NO 15/728714
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/03 (20130101)
A61K 31/13 (20130101)
A61K 31/035 (20130101)
A61K 31/40 (20130101)
A61K 31/196 (20130101) Original (OR) Class
A61K 31/341 (20130101)
A61K 31/381 (20130101)

Acyclic or Carbocyclic Compounds
C07C 229/34 (20130101)
C07C 229/38 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1096 (20130101)

Enzymes
C12Y 206/01013 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/411 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632091 Snodgrass et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) VISTAGEN THERAPEUTICS, INC. (South San Francisco, California)
ASSIGNEE(S) VISTAGEN THERAPEUTICS, INC. (South San Francisco, California)
INVENTOR(S) H. Ralph Snodgrass (South San Francisco, California);  Allen E. Cato (Durham, North Carolina);  Jack S. Hicklin (San Diego, California)
ABSTRACT Compositions of L-4-chlorokynurenine are provided, as are methods for the treatment of neurologica dyslinction.
FILED Monday, May 14, 2018
APPL NO 15/978855
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/198 (20130101) Original (OR) Class
A61K 31/198 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632099 Croatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of North Carolina at Greensboro (Greensboro, North Carolina);  Cedric Pearce (Chapel Hill, North Carolina)
ASSIGNEE(S) University of North Carolina at Greensboro (Greensboro, North Carolina)
INVENTOR(S) Mitchell P. Croatt (Greensboro, North Carolina);  Lara Fakhouri (Greensboro, North Carolina);  Nicholas H. Oberlies (Greensboro, North Carolina);  Cedric Pearce (Chapel Hill, North Carolina)
ABSTRACT This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones.
FILED Friday, August 30, 2019
APPL NO 16/556626
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/336 (20130101)
A61K 31/365 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)

Heterocyclic Compounds
C07D 313/00 (20130101)
C07D 493/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632121 Mellinghoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Ingo Kai Mellinghoff (New York, New York);  Sara Kubek (Seattle, Washington)
ABSTRACT In certain embodiments the present invention involves methods of killing tumor cells that comprise an oncogenic PDGFR mutation, and methods of treating subjects having tumors that comprise such tumor cells. In some embodiments such methods involve using PI3K inhibitors, or a combination of a PI3K inhibitor and an mTOR inhibitor, or a dual PI3K/mTOR inhibitor. The present invention also provides methods for determining whether a subject is a candidate for treatment, methods for evaluating the efficacy of treatment, and other methods, compositions, model systems, and assays.
FILED Friday, May 15, 2015
APPL NO 15/311582
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101)
A61K 31/498 (20130101)
A61K 31/519 (20130101) Original (OR) Class
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632122 Hol et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Wilhelmus G. J. Hol (Seattle, Washington);  Eric T. Larson (Seattle, Washington);  Dustin James Maly (Seattle, Washington);  Wesley C. Van Voorhis (Seattle, Washington);  Ethan Merritt (Seattle, Washington);  Kayode K. Ojo (Seattle, Washington)
ABSTRACT The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
FILED Thursday, May 02, 2019
APPL NO 16/402227
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class
A61K 31/4985 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/02 (20180101)
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/411 (20180101)
Y02A 50/488 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632140 Pavel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Ana Brandusa Pavel (New York, New York);  Joshua David Campbell (Sharon, Massachusetts);  Marc Elliott Lenburg (Brookline, Massachusetts);  Avrum Elliot Spira (Newton, Massachusetts)
ABSTRACT The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs.
FILED Tuesday, April 23, 2019
APPL NO 16/391473
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6886 (20130101)
C12Q 2539/10 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57423 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632152 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Chia-Yung Wu (San Francisco, California);  James Onuffer (Alameda, California);  Wendell A. Lim (San Francisco, California)
ABSTRACT The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
FILED Friday, August 04, 2017
APPL NO 15/669707
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 47/6891 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 14/705 (20130101)
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 14/70575 (20130101)
C07K 14/70578 (20130101)
C07K 16/18 (20130101)
C07K 16/2803 (20130101)
C07K 16/2866 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/03 (20130101)
C07K 2319/20 (20130101)
C07K 2319/33 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/14 (20130101)
C12N 9/90 (20130101)
C12N 2510/00 (20130101)

Enzymes
C12Y 502/01008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632153 Spees
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (Burlington, Vermont)
ASSIGNEE(S) THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (Burlington, Vermont)
INVENTOR(S) Jeffrey Spees (Colchester, Vermont)
ABSTRACT The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such compositions.
FILED Monday, January 29, 2018
APPL NO 15/882767
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101) Original (OR) Class
A61K 38/30 (20130101)
A61K 38/195 (20130101)
A61K 38/1833 (20130101)
A61K 38/1866 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/069 (20130101)
C12N 5/0657 (20130101)
C12N 2501/10 (20130101)
C12N 2501/12 (20130101)
C12N 2501/105 (20130101)
C12N 2501/165 (20130101)
C12N 2502/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632155 Tseng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) TissueTech, Inc. (Miami, Florida)
ASSIGNEE(S) TISSUETECH, INC. (Miami, Florida)
INVENTOR(S) Scheffer Tseng (Pinecrest, Florida);  Hua He (Miami, Florida);  Wei Li (Shenzhen, China PRC)
ABSTRACT Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
FILED Wednesday, January 24, 2018
APPL NO 15/879042
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/982 (20130101)
A61K 9/06 (20130101)
A61K 9/08 (20130101)
A61K 9/0014 (20130101)
A61K 9/19 (20130101)
A61K 9/0048 (20130101)
A61K 9/0053 (20130101)
A61K 31/738 (20130101)
A61K 35/48 (20130101)
A61K 35/50 (20130101) Original (OR) Class
A61K 38/39 (20130101)
A61K 38/1709 (20130101)
A61K 38/1709 (20130101)
A61K 38/4886 (20130101)
A61K 38/4886 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2800/74 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/40 (20130101)
A61L 15/44 (20130101)
A61L 2300/64 (20130101)
A61L 2300/412 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 19/00 (20130101)

Peptides
C07K 14/78 (20130101)
C07K 14/4702 (20130101)
C07K 14/4718 (20130101)
C07K 14/8114 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632170 Lambris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) John D. Lambris (Bryn Mawr, Pennsylvania);  Maciej M. Markiewski (Collegeville, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John D. Lambris (Bryn Mawr, Pennsylvania);  Maciej M. Markiewski (Collegeville, Pennsylvania)
ABSTRACT Methods for treating, preventing or delaying onset of tumor formation and other forms of cancer are disclosed. The methods involve administration of a complement inhibitor to inhibit C5a receptor signaling in the tumor microenvironment.
FILED Thursday, February 19, 2009
APPL NO 12/918101
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632175 Goodyear et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Joslin Diabetes Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Joslin Diabetes Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Laurie J. Goodyear (Southborough, Massachusetts);  Kristin I. Stanford (Roslindale, Massachusetts)
ABSTRACT The present invention is related to methods and compositions effective in regulating glycemic control in subject individuals in need of the regulation of glycemic control. Said individuals may have diabetes or be prediabetic condition receive therapeutically effective amounts of identified secreted proteins in an amount suitable for modulating glycemic control and to thereby treat or prevent diabetes in said subject.
FILED Tuesday, March 04, 2014
APPL NO 14/771677
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101)
A61K 38/1841 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632178 Whitsett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) Jeffrey A. Whitsett (Cincinnati, Ohio);  Machiko Ikegami (Cincinnati, Ohio)
ABSTRACT Surfactant protein D (SP-D) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (BPD).
FILED Wednesday, November 14, 2018
APPL NO 16/190456
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/395 (20130101) Original (OR) Class
A61K 38/395 (20130101)
A61K 38/1732 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632180 Dubal
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dena Dubal (Oakland, California)
ABSTRACT Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides.
FILED Friday, February 05, 2016
APPL NO 15/548306
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/47 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)

Enzymes
C12Y 302/01031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632184 Livengood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Takeda Vaccines, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) TAKEDA VACCINES, INC. (Cambridge, Massachusetts)
INVENTOR(S) Jill Ann Livengood (Fort Collins, Colorado);  Timothy Duane Powell (Maynard, Massachusetts)
ABSTRACT Embodiments herein relate to compositions and methods for stabilizing live alphaviruses. Other embodiments relate to compositions and methods for reducing degradation of live, attenuated alphaviruses. Certain embodiments relate to providing a stabilizing composition while reducing immune reaction in a subject to excipients that stabilize the live alphaviruses by providing improved formulations. Yet other embodiments relate to uses of compositions disclosed herein in kits for portable applications and methods wherein the compositions reduce degradation of the live alphaviruses.
FILED Monday, March 27, 2017
APPL NO 16/088816
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 47/26 (20130101)
A61K 47/183 (20130101)
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/36134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632185 Kinney
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Claire Y. H. Kinney (Fort Collins, Colorado)
ABSTRACT Chimeric flaviviruses that include non-coding regions, non-structural proteins, a capsid (C) protein and a portion of a premembrane (prM) signal sequence from West Nile virus (WNV), and a portion of a prM signal sequence, a prM protein and an E protein from Zika virus (VIKV) are described. Also described are compositions and methods for eliciting an immune response in a subject, such as an immune response directed against ZIKV. Diagnostic assays that utilize chimeric West Nile/Zika viruses are further described.
FILED Thursday, July 06, 2017
APPL NO 16/315897
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/525 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/24122 (20130101)
C12N 2770/24134 (20130101)
C12N 2770/24141 (20130101)
C12N 2770/24144 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/533 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/392 (20180101)
Y02A 50/394 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632188 Bronshtein
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Universal Stabilization Technologies, Inc. (San Diego, California)
ASSIGNEE(S) UNIVERSAL STABILIZATION TECHNOLOGIES, INC. (San Diego, California)
INVENTOR(S) Victor Bronshtein (San Diego, California)
ABSTRACT The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications.
FILED Friday, June 30, 2017
APPL NO 15/638937
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/145 (20130101)
A61K 35/744 (20130101)
A61K 39/07 (20130101)
A61K 39/09 (20130101)
A61K 39/12 (20130101)
A61K 39/205 (20130101) Original (OR) Class
A61K 2039/5252 (20130101)
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/20134 (20130101)
C12N 2760/20161 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632190 Sampson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) John H. Sampson (Durham, North Carolina);  Duane A. Mitchell (Durham, North Carolina)
ABSTRACT The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided.
FILED Monday, August 14, 2017
APPL NO 15/676330
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2039/53 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5156 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16122 (20130101)
C12N 2710/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632247 Woods et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CLPH, LLC (Palo Alto, California)
ASSIGNEE(S)
INVENTOR(S) Christopher E. Woods (Palo Alto, California);  Christian S. Eversull (Palo Alto, California);  Stephen A. Leeflang (Sunnyvale, California)
ABSTRACT Systems and methods are provided for imaging cardiac tissue using fluorescent dyes delivered into tissue. A distal end of an imaging device may be introduced into a chamber of the heart, and fluorescent dye may be delivered into one or more body lumens in the heart such that the dye is absorbed by cardiac tissue adjacent the chamber. Images of the cardiac tissue adjacent the chamber may be acquired using the imaging device, the dye enhancing identifying cardiac electrical activity within the cardiac tissue. Optionally, based on the identified cardiac electrical activity, tissue within the heart may be ablated or otherwise treated.
FILED Friday, January 23, 2015
APPL NO 14/604671
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0044 (20130101)
A61B 5/0071 (20130101)
A61B 5/0084 (20130101)
A61B 5/0215 (20130101)
A61B 5/0402 (20130101)
A61B 18/24 (20130101)
A61B 2018/00386 (20130101)
A61B 2018/00577 (20130101)
A61B 2018/00648 (20130101)
A61B 2018/00839 (20130101)
A61B 2018/00982 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/007 (20130101) Original (OR) Class
A61M 25/10 (20130101)
A61M 2210/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632305 Bloch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Robert J. Bloch (Baltimore, Maryland);  Andrea O'Neill (Towson, Maryland);  Joseph A. Roche (Balitmore, Maryland);  Paraskevi Sakellariou (Athens, Greece)
ABSTRACT Studies of the pathogenic mechanisms underlying human myopathies and muscular dystrophies often require animal models, but models of some human diseases are not yet available. The present invention provides methods to promote the engraftment and development of myogenic cells from individuals with such diseases into mature muscle tissue in mice to treat muscle diseases, muscle injury and reduced muscle function. Immortalized human myogenic precursor cells (hMPCs) form mature human myofibers following implantation into the hindlimbs of immunodeficient mice. The engraftment of the cells and their development into mature muscle myofibers is promoted by intermittent neuromuscular electrical stimulation (iNMES) of the peroneal nerve of the engrafted limb. The human myofibers that form are innervated, their contractile apparatus is fully differentiated, and they are comprised of human myonuclei, with minimal contamination by murine myonuclei.
FILED Friday, October 17, 2014
APPL NO 15/029191
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)
A01K 2207/12 (20130101)
A01K 2227/105 (20130101)
A01K 2267/035 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/08 (20130101)
A61F 2002/0894 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/326 (20130101) Original (OR) Class
A61N 1/36003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632464 Schenk zu Schweinsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Alere San Diego Inc. (San Diego, California)
ASSIGNEE(S) ALERE SAN DIEGO, INC. (San Diego, California)
INVENTOR(S) Alexander Schenk zu Schweinsberg (Jena, Germany);  Austin Matthew Derfus (Solana Beach, California);  Justin Davidson (San Diego, California);  Karthikeyan Kumaravadivelu (San Diego, California);  Maulik Vinod Patel (La Crescenta, California);  Olaf Piepenburg (Saffron Walden, United Kingdom);  Catherine Jean Greenwood (Sawbridgeworth, United Kingdom);  Oliver Nentwich (Cambridge, United Kingdom)
ABSTRACT A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.
FILED Tuesday, February 27, 2018
APPL NO 15/906899
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5029 (20130101)
B01L 3/502715 (20130101) Original (OR) Class
B01L 2200/027 (20130101)
B01L 2200/082 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0478 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/14 (20130101)
G01N 1/38 (20130101)
G01N 35/00069 (20130101)
G01N 2001/028 (20130101)
G01N 2035/00158 (20130101)
G01N 2035/1034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633324 Bazan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana);  University of Southern California (Los Angeles, California)
ASSIGNEE(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Nicolas G. Bazan (New Orleans, Louisiana);  Nicos A. Petasis (Los Angeles, California)
ABSTRACT This disclosure provides compounds, pharmaceutical compositions, and methods of use for the prevention and treatment of inflammatory diseases or degenerative diseases including neurodegenerative diseases. Embodiments of the present disclosure provide compounds related to very long chain polyunsaturated fatty acids, pharmaceutical compositions containing the provided compounds, and methods of treating a subject with a condition or disease using provided compounds or pharmaceutical compositions.
FILED Tuesday, February 09, 2016
APPL NO 15/549676
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/202 (20130101)
A61K 31/232 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
A61P 29/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 57/03 (20130101) Original (OR) Class
C07C 59/42 (20130101)
C07C 69/587 (20130101)
C07C 69/732 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/10 (20130101)
C07F 9/106 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633348 Treon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Steven P. Treon (Jamaica Plain, Massachusetts);  Sara Jean Buhrlage (Somerville, Massachusetts);  Nathanael S. Gray (Boston, Massachusetts);  Li Tan (Shanghai, China PRC);  Guang Yang (Natick, Massachusetts)
ABSTRACT The present invention provides compounds of any one of Formulae (A), (I-11), (II), and (V) (e.g., compounds of Formula (A-1)-(A-18)), and methods for treating Waldenström's macroglobulinemia (WM) and other B cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. Also provided are methods to treat B cell neoplasms using the compounds in combination with inhibitors of Bruton's tyrosine kinase (BTK), interleukin-1 receptor-associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 4 (IRAK4), bone marrow on X chromosome kinase (BMX), phosphoinositide 3-kinase (PI3K), transforming growth factor b-activated kinase-1 (TAK1), and/or a Src family kinase.
FILED Tuesday, December 19, 2017
APPL NO 15/847430
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/506 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 239/47 (20130101) Original (OR) Class
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 413/12 (20130101)
C07D 417/04 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633370 Huryn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Frederick National Laboratory for Cancer Research (FNLCR)
Federally Funded Research and Development Center (FFRDC)
Operated by Leidos Biomedical Research, Inc. (LBRI) at Frederick, MD
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  National Institutes of Health, A Component of the U.S. Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  National Institutes of Health, A Component of the U.S. Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Donna M. Huryn (Allentown, New Jersey);  Peter Wipf (Pittsburgh, Pennsylvania);  Matthew G. LaPorte (Pittsburgh, Pennsylvania);  Raffaele Colombo (Pittsburgh, Pennsylvania);  Marina Kovaliov (Pittsburgh, Pennsylvania);  Chaemin Lim (Pittsburgh, Pennsylvania);  Celeste Natalie Alverez (Pittsburgh, Pennsylvania);  Zhizhou Yue (Pittsburgh, Pennsylvania);  Lalith Palitha Samankumara (Pittsburgh, Pennsylvania);  Alexander Julian Chatterley (Pittsburgh, Pennsylvania);  Yongzhao Yan (Pittsburgh, Pennsylvania);  Mary Liang (Pittsburgh, Pennsylvania);  Neal J. Green (Newton, Massachusetts);  Eric T. Baldwin (Upper Holland, Pennsylvania);  William J. Moore (Hagerstown, Maryland);  Michelle Arkin (San Francisco, California);  R. Jeffrey Neitz (Oakland, California);  Kean-Hooi Ang (Oakland, California);  Clifford Bryant (Oakland, California);  Stacie Bulfer (Oakland, California)
ABSTRACT The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.
FILED Thursday, October 20, 2016
APPL NO 15/769987
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/10 (20130101)
C07D 401/14 (20130101)
C07D 405/14 (20130101) Original (OR) Class
C07D 413/14 (20130101)
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633374 Spiegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) David Spiegel (New Haven, Connecticut);  Anthony Rullo (Hamilton, Canada)
ABSTRACT The present invention relates to chimeric (including bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic cancer where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells. The compounds bind to the urokinase-type plasminogen activator receptor (uPAR) on the surface of a cancer cell, including a metastatic cancer cell, and consequently recruit native antibodies of the patient or subject where the antibodies can selectively degrade and/or deactivate targeted cancer cells through antibody-dependent cellular phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) against a large number and variety of cancers, thus providing cancer cell death and an inhibition of growth, elaboration and/or metastasis of the cancer, including remission and cure of the patient's cancer.
FILED Tuesday, February 06, 2018
APPL NO 15/890040
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/451 (20130101)
A61K 31/451 (20130101)
A61K 31/454 (20130101)
A61K 31/454 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 211/60 (20130101)
C07D 413/04 (20130101) Original (OR) Class

Peptides
C07K 16/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633385 Janda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Kim D. Janda (La Jolla, California);  Nicholas T. Jacob (San Diego, California);  Jonathan W. Lockner (San Diego, California)
ABSTRACT There are disclosed imidazolinopyrimidinone compounds that have activity to induce TRAIL gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of Formula I herein.
FILED Wednesday, March 20, 2019
APPL NO 16/359633
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)

Heterocyclic Compounds
C07D 471/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633404 Klenc et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Jeffrey Klenc (Atlanta, Georgia);  Malgorzata Lipowska (Atlanta, Georgia);  Andrew Taylor (Atlanta, Georgia)
ABSTRACT This disclosure relates to compositions comprising substituted iminodiacetic acid ligands and metal tricarbonyl complexes containing the ligands and derivatives thereof. In certain embodiments, the metal tricarbonyl complexes are used as radioisotope tracers such as renal tracers. In certain embodiments, the metal complexes comprise 99mTc or Re. In certain embodiments, the ligands are substituted with a fluorine, a fluorine-18 (F18) radioisotope, or other radionuclide.
FILED Thursday, March 10, 2016
APPL NO 15/557453
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/4057 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0402 (20130101)
A61K 51/0478 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/004 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 13/00 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/5088 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633411 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Zhijian Chen (Dallas, Texas);  Lijun Sun (Dallas, Texas);  Jiaxi Wu (Dallas, Texas);  Heping Shi (Dallas, Texas);  Chuo Chen (Dallas, Texas)
ABSTRACT Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
FILED Monday, November 18, 2019
APPL NO 16/687356
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7084 (20130101)
A61K 39/39 (20130101)
A61K 2039/55511 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/25 (20130101)
C12Q 1/6876 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101)
G01N 33/573 (20130101)
G01N 2333/9015 (20130101)
G01N 2333/9125 (20130101)
G01N 2400/00 (20130101)
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633417 McIntosh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) J. Michael McIntosh (Salt Lake City, Utah)
ABSTRACT The present disclosure describes analog conotoxin peptides of the α-contoxin peptide RgIA. These analog conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain, inflammatory conditions, inflammation, and/or cancer.
FILED Friday, May 30, 2014
APPL NO 14/894967
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
C07K 14/43504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633422 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Gabriele Neumann (Madison, Wisconsin);  Jihui Ping (Madison, Wisconsin)
ABSTRACT A vector, composition and method to improve influenza virus replication by inhibiting miRNA lec-7C binding to influenza virus mRNA and/or cRNA.
FILED Wednesday, June 01, 2016
APPL NO 15/170556
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 2039/525 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 2760/16121 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16151 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633424 Mohammadi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Moosa Mohammadi (Scarsdale, New York);  Regina Goetz (New York, New York)
ABSTRACT The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF19 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention.
FILED Wednesday, February 14, 2018
APPL NO 15/896469
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1825 (20130101)
A61K 38/1825 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/50 (20130101) Original (OR) Class
C07K 14/501 (20130101)
C07K 14/503 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633425 Antipov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) SILVER CREEK PHARMACEUTICALS, INC. (San Francisco, California)
ASSIGNEE(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
INVENTOR(S) Laura D. J. Antipov (Oakland, California);  Shawdee Eshghi (Oakland, California);  Kristopher M. Kuchenbecker (Los Angeles, California);  Bjorn L. Millard (Orinda, California);  Matthew D. Onsum (El Cerrito, California);  Andrea D. Nickerson (San Francisco, California);  Timothy R. Stowe (San Francisco, California);  Yan Zhang (San Francisco, California)
ABSTRACT Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue.
FILED Tuesday, July 03, 2018
APPL NO 16/026319
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/65 (20130101) Original (OR) Class
C07K 14/765 (20130101)
C07K 2319/33 (20130101)
C07K 2319/035 (20130101)
C07K 2319/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633441 Adusumilli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Prasad S. Adusumilli (New York, New York);  Michel Sadelain (New York, New York);  Dimiter S. Dimitrov (Frederick, Maryland);  Yang Feng (Frederick, Maryland)
ABSTRACT The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity.
FILED Friday, December 02, 2016
APPL NO 15/368278
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/00 (20130101)
A61K 38/00 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/705 (20130101)
C07K 14/4748 (20130101)
C07K 14/7051 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 16/28 (20130101) Original (OR) Class
C07K 16/30 (20130101)
C07K 2317/21 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633447 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (the Government) (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Tianlei Ying (Shanghai, China PRC)
ABSTRACT Fc domains and CH3 domains are disclosed that bind the neonatal Fc (FcRn) receptor and are at least 99% monomeric. Monomeric Fc domain molecules and CH3 domain molecules are disclosed herein that include a monomeric Fc domain or a monomeric CH3 domain and an effector molecule. In some embodiments, the monomeric Fc or monomeric CH3 domain include amino acid substitutions and/or CDR insertions in the beta strands such that they specifically bind an antigen. Methods for using these monomeric Fc domains, monomeric CH3 domains, monomeric Fc domain molecules and CH3 domain molecules are also provided.
FILED Tuesday, May 09, 2017
APPL NO 15/590981
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/00 (20130101)
C07K 16/283 (20130101) Original (OR) Class
C07K 16/1045 (20130101)
C07K 16/1063 (20130101)
C07K 2317/21 (20130101)
C07K 2317/31 (20130101)
C07K 2317/52 (20130101)
C07K 2317/55 (20130101)
C07K 2317/64 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
C07K 2317/565 (20130101)
C07K 2317/569 (20130101)
C07K 2318/20 (20130101)
C07K 2319/30 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16111 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/544 (20130101)
G01N 33/573 (20130101)
G01N 33/6863 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633450 Kohrt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Holbrook Kohrt (San Francisco, California);  Roch Houot (Rennes, France);  Ronald Levy (Stanford, California);  Arash Ash Alizadeh (San Mateo, California);  Matthew J. Goldstein (Hillsborough, California);  James Torchia (Stanford, California)
ABSTRACT Methods are provided to enhance the efficacy of antibody therapy directed to tumor cells.
FILED Friday, August 04, 2017
APPL NO 15/669418
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Peptides
C07K 16/32 (20130101)
C07K 16/2863 (20130101)
C07K 16/2878 (20130101)
C07K 16/2887 (20130101)
C07K 16/2893 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 16/3015 (20130101)
C07K 16/3023 (20130101)
C07K 16/3046 (20130101)
C07K 16/3069 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/75 (20130101)
C07K 2317/732 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/70578 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633636 Shah et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Khalid Shah (Andover, Massachusetts);  Kaoru Tamura (Tokyo, Japan);  Hiroaki Wakimoto (Newton, Massachusetts)
ABSTRACT Disclosed herein is a recombinant oncolytic virus comprising a nucleic acid sequence encoding tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). One such oncolytic virus is oHSV. One form of TRAIL contained within the oncolytic virus is a secreted form of TRAIL. Examples of various forms of oHSV and secreted TRAIL are disclosed therein. Also disclosed are host cells and therapeutic formulations comprising the recombinant oncolytic virus. Also disclosed are methods of treating cancer in a subject by administering a therapeutic formulation comprising the recombinant oncolytic virus to the subject.
FILED Tuesday, December 05, 2017
APPL NO 15/832109
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/763 (20130101)
A61K 38/19 (20130101)

Peptides
C07K 14/525 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2710/16632 (20130101)
C12N 2710/16642 (20130101)
C12N 2710/16671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633642 Joung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) J. Keith Joung (Winchester, Massachusetts);  Benjamin Kleinstiver (Medford, Massachusetts);  Vikram Pattanayak (Wellesley, Massachusetts)
ABSTRACT Engineered CRISPR-Cas9 nucleases with improved specificity and their use in genomic engineering, epigenomic engineering, genome targeting, and genome editing.
FILED Tuesday, October 09, 2018
APPL NO 16/155808
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 9/22 (20130101) Original (OR) Class
C12N 15/90 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101)
C12N 2800/22 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633648 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Anna Kuchina (Seattle, Washington);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers.
FILED Friday, February 10, 2017
APPL NO 15/430108
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1037 (20130101) Original (OR) Class
C12N 15/1065 (20130101)
C12N 15/1065 (20130101)
C12N 15/1068 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2525/191 (20130101)
C12Q 2563/103 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633653 Khvorova et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Anastasia Khvorova (Westborough, Massachusetts);  Mehran Nikan (Boston, Massachusetts);  Matthew Hassler (Worcester, Massachusetts);  Maire Osborn (Boston, Massachusetts);  Reka Haraszti (Boston, Massachusetts);  Andrew Coles (Boston, Massachusetts);  Anton Turanov (Boston, Massachusetts);  Neil Aronin (Newtonville, Massachusetts)
ABSTRACT Provided herein are self-delivering oligonucleotides that are characterized by efficient RISC entry, minimum immune response and off-target effects, efficient cellular uptake without formulation, and efficient and specific tissue distribution.
FILED Friday, August 12, 2016
APPL NO 15/236051
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/61 (20170801)
A61K 47/542 (20170801)
A61K 47/554 (20170801)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/3515 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633655 Kay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Mark A. Kay (Los Altos, California);  Hak Kyun Kim (Palo Alto, California);  Shengchun Wang (Union City, California)
ABSTRACT The present invention features compositions and methods relating to tRNA-derived small RNAs (tsRNAs). Provided herein are oligonucleotide compositions that are complementary to tsRNAs, in particular leuCAGtsRNA, and methods of using the oligonucleotides for the regulation of respective tsRNA. Further provided are methods of inducing apoptosis through the inhibition of leuCAGtsRNA.
FILED Thursday, July 21, 2016
APPL NO 15/216546
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/606 (20130101)
A61K 31/606 (20130101)
A61K 31/635 (20130101)
A61K 31/635 (20130101)
A61K 31/712 (20130101)
A61K 31/712 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
C12N 2310/341 (20130101)
C12N 2310/3231 (20130101)
C12N 2310/3231 (20130101)
C12N 2320/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633662 Pillay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Sirika Pillay (Hayward, California);  Jan Carette (Palo Alto, California);  Michael Stewart Chapman (Lake Oswego, Oregon);  Nancy Meyer (Portland, Oregon);  Andreas Puschnik (Palo Alto, California);  Omar Davulcu (Portland, Oregon)
ABSTRACT Compositions and methods are provided for modulating adeno-associated virus (AAV) infection. For example, compositions and methods are provided for enhancing permissiveness of a target cell to AAV infection (e.g., by increasing levels of AAVR (KIAA0319L) in the cell), for reducing permissiveness of a target cell to AAV infection (e.g., by reducing levels of AAVR in the cell), and for nucleic acid delivery (e.g., by (i) increasing permissiveness of a target cell to AAV infection, e.g., by increasing the amount of AAVR in the cell; and (ii) contacting the target cell with an AAV particle that includes a nucleic acid of interest). Also provided are screening methods and kits for practicing the methods of the disclosure.
FILED Wednesday, November 09, 2016
APPL NO 15/774223
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/113 (20130101)
C12N 15/625 (20130101)
C12N 15/1138 (20130101) Original (OR) Class
C12N 15/8509 (20130101)
C12N 2015/859 (20130101)
C12N 2015/8581 (20130101)
C12N 2310/14 (20130101)
C12N 2330/50 (20130101)
C12N 2710/10032 (20130101)
C12N 2750/14152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633675 Ajikumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  National University of Singapore (Singapore, Singapore)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  National University of Singapore (Singapore, Singapore)
INVENTOR(S) Parayil K. Ajikumar (Cambridge, Massachusetts);  Gregory Stephanopoulos (Winchester, Massachusetts);  Heng Phon Too (Singapore, Singapore)
ABSTRACT The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
FILED Tuesday, July 10, 2018
APPL NO 16/031509
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/007 (20130101) Original (OR) Class
C12P 7/42 (20130101)
C12P 9/00 (20130101)
C12P 15/00 (20130101)
C12P 17/02 (20130101)
C12P 19/56 (20130101)
C12P 23/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 2600/158 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 999/99 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633695 Vo-Dinh et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Tuan Vo-Dinh (Chapel Hill, North Carolina);  Hsin-Neng Wang (Durham, North Carolina);  Andrew Fales (Durham, North Carolina)
ABSTRACT Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesirable cells in a subject.
FILED Tuesday, September 22, 2015
APPL NO 14/861353
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101) Original (OR) Class
C12Q 1/6825 (20130101)
C12Q 2525/301 (20130101)
C12Q 2563/137 (20130101)
C12Q 2563/155 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633704 Johnson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Raymond M. Johnson (Branford, Connecticut)
ASSIGNEE(S)
INVENTOR(S) Raymond M. Johnson (Branford, Connecticut)
ABSTRACT A previously unknown T cell receptor (TCR) activation pathway dependent on the aryl hydrocarbon receptor conferring resistance to calcineurin inhibitors and mTOR inhibitors is disclosed, including application of this pathway to the diagnosis and treatment of certain disease states refractory to treatment with calcineurin inhibitors. This alternative TCR activation pathway uniquely exists in a subset of CD8 T cells expanded in the setting of chronic rejection or rheumatoid arthritis. Expansion of this newly discovered calcineurin and mTOR inhibitor resistant CD8 T cell subset in humans can be quantified by measuring levels of certain biomarkers in the circulating CD8 T cell pool, such as Pla2g4a, to diagnose disease states mediated thereby. Additionally, methods for diagnosing ongoing active inflammation mediated by this resistant CD8 T cell subset in either chronic rejection or rheumatoid arthritis are provided, which comprise measuring levels of the biomarker Scin in the circulating CD8 T cell pool.
FILED Monday, July 25, 2016
APPL NO 15/218141
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101)
G01N 33/577 (20130101)
G01N 33/5047 (20130101)
G01N 33/6893 (20130101)
G01N 2333/47 (20130101)
G01N 2800/24 (20130101)
G01N 2800/52 (20130101)
G01N 2800/102 (20130101)
G01N 2800/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633766 Haff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Central Oklahoma (Edmond, Oklahoma)
ASSIGNEE(S) University of Central Oklahoma (Edmond, Oklahoma)
INVENTOR(S) Maurice Haff (Edmond, Oklahoma);  Morshed Khandaker (Edmond, Oklahoma);  William Paul Snow (Edmond, Oklahoma)
ABSTRACT An apparatus for collecting cross-aligned fiber threads, comprising an elongated assembly having a plurality of segments including at least a first segment, a second segment, and an intermediate segment, the first segment positioned at one end of the intermediate segment and the second segment positioned at an opposite end of the intermediate segment, each segment being electrically chargeable; an electrically chargeable emitter for electrospinning nanoscale fiber streams comprising charged fiber branches, the emitter having a tip positioned offset and between an edge of the first segment and an edge of the second segment; a support structure for rotating the elongated assembly about a longitudinal axis and applying an electrical charge to at least the edges of the first and second segment; at least one electrically chargeable steering electrode for attracting fiber streams, the at least one steering electrode chargeable with an electrical polarity opposing a charge applied to the emitter.
FILED Thursday, July 11, 2019
APPL NO 16/508620
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/34 (20130101)
D01D 5/0084 (20130101) Original (OR) Class

Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding
D04H 1/728 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2331/041 (20130101)
D10B 2509/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634587 Tseng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hsian-Rong Tseng (Los Angeles, California);  Mitch A. Garcia (Malibu, California);  Min Song (Los Angeles, California);  Libo Zhao (Los Angeles, California);  Shuang Hou (Los Angeles, California);  Tom Lee (Redondo Beach, California)
ABSTRACT A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.
FILED Monday, April 09, 2018
APPL NO 15/948495
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502761 (20130101)
B01L 9/527 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0883 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101) Original (OR) Class
G01N 1/286 (20130101)
G01N 1/4077 (20130101)
G01N 33/574 (20130101)
G01N 33/56966 (20130101)
G01N 2001/284 (20130101)
G01N 2001/2886 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634637 Potyrailo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Radislav Alexandrovich Potyrailo (Niskayuna, New York);  Cheryl Margaret Surman (Albany, New York);  Binil Kandapallil (Mechanicville, New York)
ABSTRACT Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over the LCR circuit. The sensing material includes a coordination compound of a ligand and a metal nanoparticle. The coordination compound has the formula: (X)n-M, where X includes an alkylamine group having the formula (R—NH2), an alkylphosphine having the formula (R3—P), an alkylphosphine oxide having the formula (R3P═O), an alkyldithiocarbamate having the formula (R2NCS2), an alkylxanthate having the formula (ROCS2), or any combination thereof, R includes an alkyl group, n is 1, 2, or 3, and M includes the metal nanoparticle of gold, silver, platinum, palladium, alloys thereof, highly conductive metal nanoparticles, or any combination thereof. The sensing material is configured to allow selective detection of at least six different analyte fluids from an analyzed fluid mixture.
FILED Thursday, October 26, 2017
APPL NO 15/794815
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/025 (20130101)
G01N 27/3278 (20130101) Original (OR) Class
G01N 33/48792 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634677 Erickson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute on Aging (NIA)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Craig Erickson (Wyoming, Ohio);  Debomoy Lahiri (Brownsburg, Indiana)
ABSTRACT Studies in mouse models of Fragile X and preliminary studies in human youth demonstrate that ERK1/2 is biomarker useful to monitoring the treatment of people diagnosed with ASD. Results reported herein demonstrate that acamprosate has the ability to reduce levels of ERK1/2 activation associated with many of the symptoms of ASD. Accordingly, in addition to its utility as a diagnostic marker for ASD ERK1/2 activation levels can be used to monitory patients treated with acamprosate.
FILED Tuesday, October 14, 2014
APPL NO 15/029596
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/16 (20130101)
A61K 31/185 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101) Original (OR) Class
G01N 2333/48 (20130101)
G01N 2333/4709 (20130101)
G01N 2333/91205 (20130101)
G01N 2500/20 (20130101)
G01N 2800/52 (20130101)
G01N 2800/2814 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634685 Nahm et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The UAB Research Foundation (Birmingham, Alabama);  Fundacao Oswaldo Cruz (Rio de Janeiro, Brazil);  Instituto Adolfo Lutz (Sao Paulo, Brazil)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  Fundacao Oswaldo Cruz (Rio de Janeiro, Brazil)
INVENTOR(S) Moon H. Nahm (Birmingham, Alabama);  Jisheng Lin (Vestavia Hills, Alabama);  Angela P. Brandao (Sao Paulo, Brazil);  Maria Cristina Brandileone (Sao Paulo, Brazil)
ABSTRACT Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}. This new serotype may be included in pneumococcal vaccines.
FILED Monday, October 02, 2017
APPL NO 15/723136
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/715 (20130101)
A61K 39/092 (20130101)

Peptides
C07K 16/1275 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/006 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/14 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 1/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101) Original (OR) Class
G01N 33/56944 (20130101)
G01N 2333/315 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634742 Garraud et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Nicolas Garraud (Gainesville, Florida);  Carlos Rinaldi (Gainesville, Florida);  David P. Arnold (Gainesville, Florida)
ABSTRACT Disclosed are various embodiments for a system configured to characterize a magnetic response of a sample. The system can comprise an electrical source configured to generate a time-varying current supply, an excitation coil system coupled to the electrical source to generate a time-vary magnetic field for application to a sample, and a sensing coil system that senses a magnetic response of the sample in response to the time-varying magnetic field. The sensing coil system can comprise a pick-up coil and a balancing coil that can be translated or rotated. The balancing coil configured to cancel a feed-through induction signal. In another embodiment, the sensing coil system can comprise an adjustable fine-tuning coil that is configured to modify an effect of the cancellation of the feed-through induction signal.
FILED Friday, October 07, 2016
APPL NO 15/766638
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/0515 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/1276 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634747 Majewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) West Virginia University (Morgantown, West Virginia)
INVENTOR(S) Stanislaw Majewski (Morgantown, West Virginia);  James Proffitt (Newport News, Virginia);  James Lewis (Morgantown, West Virginia);  Julie Brefczynski-Lewis (Morgantown, West Virginia);  Alexander Stolin (Morgantown, West Virginia)
ABSTRACT A Positron Emission Tomography (“PET”) insert for use with a Magnetic Resonance Imaging (“MRI”) scanning device, the PET insert including a plurality of photodetector modules provided adjacent each other in an array, the plurality of photodetector modules configured for placement adjacent a body of a patient and sized to be received in a magnetic bore of the MRI scanning device with the patient, the photodetector modules providing detection of gamma annihilation photons, and a Radio Frequency (“RF”) coil provided between the patient and the plurality of photodetector modules. Each of the plurality of photodetector modules includes a pixelated scintillator array provided for alignment adjacent the patient's body, and a shielding block including silicon photomultiplier pads and passive electronic circuitry only.
FILED Thursday, March 14, 2013
APPL NO 13/827557
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/481 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 1/1603 (20130101)
G01T 1/2985 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634899 Gopinath et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S) Juliet T. Gopinath (Boulder, Colorado);  Emily A. Gibson (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Richard Weir (Longmont, Colorado);  Diego Restrepo (Littleton, Colorado);  Baris Ozbay (Denver, Colorado)
ABSTRACT The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques.
FILED Thursday, January 22, 2015
APPL NO 15/113303
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/14 (20130101)
G02B 6/06 (20130101)
G02B 21/006 (20130101)
G02B 21/0032 (20130101)
G02B 21/0076 (20130101)
G02B 23/26 (20130101)
G02B 23/243 (20130101) Original (OR) Class
G02B 23/2446 (20130101)
G02B 23/2469 (20130101)
G02B 26/005 (20130101)

Pictorial Communication, e.g Television
H04N 5/2256 (20130101)
H04N 2005/2255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637575 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Xinyu Zhang (Madison, Wisconsin);  Chi Zhang (Madison, Wisconsin)
ABSTRACT A system for identifying the location of the mobile device uses standard fluorescent light fixtures commonly found in indoor environments and detects minor variations in the light output of those fixtures caused by normal manufacturing variation. These variations are catalogued as identifying fingerprints together with location of the light fixtures to provide for navigation.
FILED Wednesday, May 25, 2016
APPL NO 15/164195
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/116 (20130101) Original (OR) Class
H04B 10/1141 (20130101)

Wireless Communication Networks
H04W 4/02 (20130101)
H04W 4/024 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10638112 Shechtman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Yoav Shechtman (Santa Clara, California);  William E. Moerner (Stanford, California);  Lucien Weiss (Los Angeles, California);  Steffen J. Sahl (Göttingen, Germany)
ABSTRACT Various embodiments include an apparatus including a phase mask and circuitry. The phase mask is configured and arranged with optics in an optical path to modify a shape of light, passed from an object. The shape modification characterizes the light as having two lobes with a lateral distance that changes along a line, having a first orientation, as a function of an axial proximity of the object to a focal plane, and with the line having a different orientation depending on whether the object is above or below the focal plane. The circuitry is configured and arranged to generate a three-dimensional image from light detected at the image plane, by using the modified shape to provide depth-based characteristics of the object.
FILED Thursday, January 17, 2019
APPL NO 16/250483
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/008 (20130101)
G02B 21/0028 (20130101)
G02B 21/0032 (20130101)
G02B 21/0056 (20130101)
G02B 21/0064 (20130101)
G02B 26/06 (20130101)

Pictorial Communication, e.g Television
H04N 13/161 (20180501)
H04N 13/214 (20180501)
H04N 13/218 (20180501) Original (OR) Class
H04N 13/271 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10631877 Murphy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of AMerica, as represented by the Secretary of the Defense (Washington, District of Columbia)
INVENTOR(S) Ryan Murphy (Columbia, Maryland);  Ehsan Basafa (Baltimore, Maryland);  Mehran Armand (Fulton, Maryland);  Chad Gordon (Lutherville, Maryland);  Gerald Grant (Goshen, Kentucky);  Peter Liacouras (North Potomac, Maryland)
ABSTRACT Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating.
FILED Wednesday, November 26, 2014
APPL NO 15/100241
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/15 (20130101) Original (OR) Class
A61B 17/176 (20130101)
A61B 17/1695 (20130101)
A61B 17/1739 (20130101)
A61B 17/8085 (20130101)
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 2034/105 (20160201)
A61B 2034/108 (20160201)
A61B 2034/2051 (20160201)
A61B 2034/2055 (20160201)
A61B 2034/2065 (20160201)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2803 (20130101)

Electric Digital Data Processing
G06F 19/3481 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/50 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/26 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632030 Powell
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Timothy E Powell (Temecula, California)
ABSTRACT A reconfigurable portable load bearing structure which can be configured into an extended load bearing configuration or a collapsed configuration, comprising of a first, second and third plurality of rail segments that are each rotatably coupled together and a plurality of support segments or pads which are configured to selectively couple and latch into one of a plurality of positions on said first, second and third plurality of rail segments.
FILED Wednesday, December 21, 2016
APPL NO 15/386510
ART UNIT 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 1/02 (20130101)
A61G 1/003 (20130101)
A61G 1/04 (20130101)
A61G 1/007 (20130101)
A61G 1/013 (20130101) Original (OR) Class
A61G 7/103 (20130101)

Construction of Bridges, or Viaducts; Assembly of Bridges
E01D 15/133 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632143 McCarthy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Materiel Development Activity (USAMMDA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Tricol Biomedical, Inc. (Portland, Oregon)
ASSIGNEE(S) Tricol Biomedical, Inc. (Portland, Oregon)
INVENTOR(S) Simon McCarthy (Portland, Oregon);  Barbara McGrath (Portland, Oregon);  Sam Kuhn (Portland, Oregon);  Jess Kimball (Portland, Oregon);  Michael Stolten (New Orleans, Louisiana);  Amanda Bennett (New Orleans, Louisiana)
ABSTRACT The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid. Chitosan materials can be mixed in solution with one or more of other hydrophilic polymers to create compositional heterogeneity and pharmaceutical agents to achieve controlled release of the agent(s) from the final forms at the site of application.
FILED Tuesday, February 13, 2018
APPL NO 15/895677
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/70 (20130101)
A61K 9/1652 (20130101)
A61K 9/1694 (20130101)
A61K 31/722 (20130101) Original (OR) Class
A61K 47/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632384 Stacy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Aptima, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Aptima, Inc. (Woburn, Massachusetts)
INVENTOR(S) E. Webb Stacy (Andover, Massachusetts);  Kevin Sullivan (Lexington, Massachusetts);  Paul Picciano (Windham, New Hampshire);  Can Keskin (Gloucester, Massachusetts)
ABSTRACT Processor based systems and methods of defining a scenario event comprising the steps of identifying an event having an event attribute and generalizing the event attribute to define a generalized event whereby the generalized event is the scenario event. In some embodiments, the steps further comprise identifying a first and second event, generalizing a first and second event attribute to define a first and second generalized event and connecting the first and second generalized event in a continuous envelope to create a scenario envelope. Processor based systems and methods of monitoring an activity comprising the steps of monitoring an activity having an activity attribute and comparing the activity attribute to an event envelope to determine a status of the activity relative to the event envelope.
FILED Wednesday, November 21, 2018
APPL NO 16/198257
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for
A63F 13/60 (20140902) Original (OR) Class
A63F 2300/6009 (20130101)
A63F 2300/8017 (20130101)

Electric Digital Data Processing
G06F 9/542 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633113 Fisher et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) AeroVironment, Inc. (Simi Valley, California)
ASSIGNEE(S) AEROVIRONMENT, INC. (Monrovia, California)
INVENTOR(S) Christopher Eugene Fisher (Leo, Indiana);  John Peter Zwaan (Simi Valley, California);  David R. Thompson (Simi Valley, California);  Marc L. Schmalzel (Simi Valley, California);  Karl R. Klingbiel (Simi Valley, California);  Tyson R. Jensen (Simi Valley, California);  Pavel Belik (Simi Valley, California);  Eric James Aagaard (Los Angeles, California)
ABSTRACT Liquid dispensing assemblies including adhesive anchoring assemblies configured to adhere to a support surface external to a device such as a vehicle. An air vehicle includes (a) a fluid adhesive container assembly detachably attached to the air vehicle, wherein the fluid adhesive container assembly comprises: (i) an adhesive container comprising fluid adhesive; and (ii) one or more fibers, wherein the one or more fibers are configured, or a brush of fibers, or a fabric of fibers, is configured to conduct the fluid adhesive and to structurally support an adhesive bond between the one or more fibers and a surface; and (b) means for dispensing the fluid adhesive from the fluid adhesive container, to the one or more fibers.
FILED Tuesday, May 01, 2018
APPL NO 15/968521
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 1/02 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/48 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/3076 (20130101)

Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/18 (20130101)

Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 1/12 (20130101) Original (OR) Class
B64F 1/16 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
Y10T 156/1788 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633420 Bishop et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) George Mason Research Foundation, Inc. (Fairfax, Virginia)
ASSIGNEE(S) GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia)
INVENTOR(S) Barney Bishop (Annandale, Virginia);  Monique van Hoek (Centreville, Virginia);  Ezra Myung Chul Chung (North Potomac, Maryland)
ABSTRACT Peptides having antimicrobial properties are described herein, as are compositions containing such peptides, and methods for using the peptides.
FILED Thursday, July 27, 2017
APPL NO 16/316646
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/10 (20200101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 2300/25 (20130101)
A61L 2300/404 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 17/02 (20180101)
A61P 31/04 (20180101)

Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633441 Adusumilli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York);  The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Prasad S. Adusumilli (New York, New York);  Michel Sadelain (New York, New York);  Dimiter S. Dimitrov (Frederick, Maryland);  Yang Feng (Frederick, Maryland)
ABSTRACT The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity.
FILED Friday, December 02, 2016
APPL NO 15/368278
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/00 (20130101)
A61K 38/00 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/705 (20130101)
C07K 14/4748 (20130101)
C07K 14/7051 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 16/28 (20130101) Original (OR) Class
C07K 16/30 (20130101)
C07K 2317/21 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633643 Pavlik et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Benjamin J. Pavlik (Lincoln, Nebraska);  Paul Blum (Lincoln, Nebraska);  Kevin Van Cott (Hickman, Nebraska)
ABSTRACT An engineered payload-delivery system includes a target cell binding unit, covalently bound to a pore forming unit, and a payload portion adapted with a region capable of non-covalently binding to the pore forming unit. The pore forming unit is derived from a particular sub-serotype of Clostridium toxin, while the payload region is derived from a different sub-serotype of Clostridium toxin. The disclosed chimeric protein-based composition is capable of specifically delivering payload to neural cells.
FILED Saturday, May 14, 2016
APPL NO 15/574151
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101)
A61K 47/6415 (20170801)
A61K 49/0056 (20130101)

Peptides
C07K 14/33 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101) Original (OR) Class
C12N 15/62 (20130101)

Enzymes
C12Y 204/02 (20130101)
C12Y 304/24069 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/469 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633695 Vo-Dinh et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Tuan Vo-Dinh (Chapel Hill, North Carolina);  Hsin-Neng Wang (Durham, North Carolina);  Andrew Fales (Durham, North Carolina)
ABSTRACT Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesirable cells in a subject.
FILED Tuesday, September 22, 2015
APPL NO 14/861353
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101) Original (OR) Class
C12Q 1/6825 (20130101)
C12Q 2525/301 (20130101)
C12Q 2563/137 (20130101)
C12Q 2563/155 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633718 Dudt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Philip Dudt (North Bethesda, Maryland);  Roshdy George Barsoum (McLean, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Philip Dudt (North Bethesda, Maryland);  Roshdy George Barsoum (McLean, Virginia)
ABSTRACT An apparatus and method for hardening and compacting an inner face of a cylindrical opening of a structure. The apparatus and method is directed towards the hardening and compaction of an elongated cylindrical opening by surrounding the inner face of the cylindrical opening with a glass tube, and initiating an explosive volume expansion of the glass. This in turn, creates a compressive force that acts on the inner face to compact and harden the surface.
FILED Friday, September 29, 2017
APPL NO 15/720111
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 26/00 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633726 Chinella
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John F. Chinella (Warwick, Maryland)
ABSTRACT A low alloy high nitrogen steel includes iron and, by weight 0.14-0.60% nitrogen (N); 0.08-0.28% carbon (C); 0.10-2.20% nickel (Ni); 0.25-2.00% manganese (Mn); 1.20-2.70% chromium (Cr); 0.45-1.50% tungsten (W); not more than 0.05% molybdenum (Mo); not more than 0.02% vanadium (V); not more than 0.60% silicon (Si); not more than 0.10% copper (Cu); not more than 0.02% titanium (Ti); not more than 0.02% niobium (Nb); not more than 0.008% aluminum (Al); and not more than 0.02% of any other element with not more than 0.10% total other elements, wherein cobalt (Co) is substitutable for any part of the nickel.
FILED Wednesday, August 16, 2017
APPL NO 15/678573
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 8/0263 (20130101)
C21D 2211/008 (20130101)

Alloys
C22C 38/001 (20130101) Original (OR) Class
C22C 38/04 (20130101)
C22C 38/30 (20130101)
C22C 38/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633754 Woodrow, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Thomas A. Woodrow, III (Lakeside, Texas);  Jean A. Nielsen (Kent, Washington)
ABSTRACT The present disclosure generally relates to the field of tin electroplating. More specifically, the present disclosure relates to methods for mitigating tin whisker formation on tin-plated films and tin-plated surfaces by doping the tin with germanium.
FILED Friday, July 05, 2013
APPL NO 13/935768
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/30 (20130101) Original (OR) Class
C25D 3/60 (20130101)
C25D 5/54 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/12715 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633981 Quach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) San Quach (East Hartford, Connecticut);  Tracy A. Propheter-Hinckley (Manchester, Connecticut);  Steven Bruce Gautschi (Naugatuck, Connecticut)
ABSTRACT A component for a gas turbine engine includes, among other things, an airfoil that includes a pressure sidewall and a suction sidewall that meet together at both a leading edge and a trailing edge, the airfoil extending radially from a platform to a tip, a tip pocket formed in the tip and terminating prior to the trailing edge, and one or more heat transfer augmentation devices formed in the tip pocket.
FILED Friday, June 01, 2018
APPL NO 15/995884
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/20 (20130101)
F01D 5/147 (20130101)
F01D 5/186 (20130101)
F01D 5/187 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/202 (20130101)
F05D 2260/221 (20130101)
F05D 2260/2212 (20130101)
F05D 2260/2214 (20130101)
F05D 2260/22141 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633990 Olson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Anders C. Olson (Bloomfield, Connecticut);  Nicholas W. Kantany (Manchester, Connecticut)
ABSTRACT A vane strut assembly is disclosed, The vane strut assembly may include a first panel, a second panel, and a coupling mechanism that couples the first panel and the second panel to one another. The coupling mechanism may include a first fitting that is attached to the first panel, a second fitting that is attached to the second panel, and a cable disposed between the first fitting and the second fitting.
FILED Monday, January 08, 2018
APPL NO 15/864341
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/02 (20130101)
F01D 9/04 (20130101)
F01D 9/041 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633994 Barker
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) William M. Barker (North Andover, Massachusetts)
ABSTRACT A seal assembly for a gas turbine engine according to an example of the present disclosure includes a seal segment. The seal segment includes a blade-sealing portion that provides an elongated slot, a flange that extends from the blade-sealing portion, and a hook that extends from the blade-sealing portion and is spaced from the flange. The hook has a surface that at least partially provides a cavity. A feather seal has an elongated portion and first and second legs which extend from the elongated portion. The first leg abuts the flange, the second leg is disposed in the cavity, and the elongated portion is disposed in the elongated slot.
FILED Wednesday, March 21, 2018
APPL NO 15/927145
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/003 (20130101)
F01D 11/005 (20130101) Original (OR) Class
F01D 11/08 (20130101)
F01D 25/24 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/11 (20130101)
F05D 2240/55 (20130101)
F05D 2240/57 (20130101)
F05D 2250/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634005 Petrillo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Dalton C. Petrillo (Norwich, Connecticut);  Christopher M. Juh (Rocky Hill, Connecticut)
ABSTRACT A flow metering and retention system includes a first disk that is annular in shape surrounding a centerline and extending axially along the centerline, a first coverplate axially rearward of the first disk with the first coverplate having an axially rearward extending arm, a second disk that is annular in shape surrounding the centerline and rearward of the first coverplate, a second coverplate at least partially between the first coverplate and the second disk; and a ring adjacent to the radially outer side of the slot of the second disk. The second disk has a slot into which the arm of the first coverplate extends with the slot having a radially outer side and a radially inner side, and the ring is configured to meter air flowing between the radially outer side of the slot and the arm of the first coverplate.
FILED Thursday, July 13, 2017
APPL NO 15/649387
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/082 (20130101)
F01D 5/3015 (20130101)
F01D 11/00 (20130101)
F01D 11/001 (20130101)
F01D 11/16 (20130101)
F01D 25/08 (20130101) Original (OR) Class
F01D 25/24 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/067 (20130101)
F02C 7/00 (20130101)
F02C 7/18 (20130101)
F02C 7/28 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/321 (20130101)
F05D 2230/90 (20130101)
F05D 2230/642 (20130101)
F05D 2230/644 (20130101)
F05D 2250/44 (20130101)
F05D 2260/33 (20130101)
F05D 2260/36 (20130101)
F05D 2260/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634092 Simpson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Alex J. Simpson (Tolland, Connecticut);  Robert T. Knowlton (Newington, Connecticut)
ABSTRACT Disclosed is a linkage assembly for a gas turbine engine having a link having a first end, a second end, and a rod extending therebetween, the first end having a first sliding bearing disposed within a first sliding bearing housing, a fastener comprising a first flange and a second flange, a pin extending between the first flange and the second flange, wherein the first sliding bearing is pivotally connected to the pin; and a biasing member secured between the first flange and the sliding bearing housing, the biasing member contacting the sliding bearing housing and biasing the link against rotation about a center axis for the rod of the link.
FILED Friday, September 08, 2017
APPL NO 15/700042
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 33/04 (20130101)
B64D 2027/268 (20130101)

Jet-propulsion Plants
F02K 1/06 (20130101) Original (OR) Class
F02K 1/1207 (20130101)
F02K 3/075 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/42 (20130101)
F05D 2250/241 (20130101)
F05D 2260/50 (20130101)

Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 7/02 (20130101)
F16C 11/02 (20130101)
F16C 11/045 (20130101)
F16C 11/0614 (20130101)
F16C 2360/43 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634153 Pinera et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Alex Pinera (Jupiter, Florida);  Stephen M Brooks (Jupiter, Florida);  Timothy J Miller (Jupiter, Florida)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Alex Pinera (Jupiter, Florida);  Stephen M Brooks (Jupiter, Florida);  Timothy J Miller (Jupiter, Florida)
ABSTRACT A turbopump is formed from a metal additive manufacturing process in which both the housing and the impeller are formed as a single piece with the impeller trapped within the single piece housing. The impeller is formed with an axial bore and a shaft is secured by a tie bolt on one end to secure forward and aft bearings within the housing after the impeller and housing have been formed.
FILED Monday, June 06, 2016
APPL NO 15/173773
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Jet-propulsion Plants
F02K 9/46 (20130101)

Non-positive-displacement Pumps
F04D 17/08 (20130101)
F04D 25/04 (20130101)
F04D 29/043 (20130101) Original (OR) Class
F04D 29/046 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634259 Grayson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Gary David Grayson (Issaquah, Washington);  Christopher C. Veto (Huntington Beach, California);  Victor John Barackman (Costa Mesa, California);  Henry Rodriguez (Diamond Bar, California)
ABSTRACT Guide vane check valve assemblies and poppets for guide vane check valve assemblies are disclosed. A guide vane poppet includes an elongate central core configured to form a fluid seal with a valve body of the check valve assembly. The guide vane poppet additionally includes an elongate outer skirt and at least one guide vane radially extending between the elongate central core and the elongate outer skirt. A check valve assembly includes a valve body with a central cavity, an inlet to the central cavity, an outlet from the central cavity, and a spring seat, and further includes a spring and a poppet. The spring is oriented to press against the poppet and to urge a poppet-side sealing surface of the poppet into sealing engagement with a body-side sealing surface of the valve body.
FILED Friday, April 19, 2019
APPL NO 16/389790
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 15/025 (20130101)
F16K 15/026 (20130101)
F16K 17/04 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 137/7938 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634466 Bishop
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael L. Bishop (Norco, California)
ABSTRACT The invention relates to sealable short-pathlength liquid transmission cells for Fourier-transform infrared spectroscopy applications. In exemplary embodiments, a liquid transmission cell with transmissions sections uses horizontal tubing for inserting and removing fluids from the cell. Angling the tubing relative to a top face of the cell allows small amounts of entrapped air to rise out of the optical path without blocking spectroscopy measurements. The tubing is silver-soldered to the body of the transmission cell to make a leak-free connection.
FILED Friday, February 01, 2019
APPL NO 16/265214
ART UNIT 2886 — Optics
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/113 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)
G01N 21/3577 (20130101)
G01N 2021/0106 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634469 Shipley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Office of the Secretary of Defense (OSD)
DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S) AAI Corporation (Hunt Valley, Maryland)
ASSIGNEE(S) AAI Corporation (Hunt Valley, Maryland)
INVENTOR(S) Paul Andrew Shipley (Millers, Maryland);  Joshua Stephen Ruck (Baltimore, Maryland);  Benjamin Tyler Cole (Baltimore, Maryland);  Brandon Scott Recchia (Parkton, Maryland);  Cameron Mehdi Brand (Bel Air, Maryland);  William Henry Engel, IV (Cockeysville, Maryland)
ABSTRACT A cased telescoped cartridge that includes a cylindrical case surrounding a projectile, a front end through which the projectile exits when the cased telescoped cartridge is fired, and a thermal protective insert located at the front end. The thermal protective insert insulates the cased telescoped cartridge from heat emanating from a barrel of a firearm into a chamber of a firearm when the cartridge is loaded into the chamber of the firearm. The thermal protective insert is made up of at least one thermally insulating material, and is integrated into the front end of the cased telescoped cartridge.
FILED Friday, March 01, 2019
APPL NO 16/290125
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 5/045 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634474 Blazek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin M. Blazek (Ridgecrest, California);  Lee R. Hardt (Ridgecrest, California);  Carl A. Weinstein (Ridgecrest, California)
ABSTRACT Embodiments are directed to a shock mitigation device including a hollow fuze well having an inner surface and an outer surface. A plurality of vents are axially spaced at equal distance about the outer surface. A shock dampening liner is affixed to the inner surface. A shock dampening ring is concentric about the hollow fuze well.
FILED Thursday, June 06, 2019
APPL NO 16/433023
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 39/14 (20130101)
F42B 39/20 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634499 Ayazi et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Farrokh Ayazi (Atlanta, Georgia);  Haoran Wen (Atlanta, Georgia)
ABSTRACT An inertial measurement apparatus has mechanically bendable beams that have an isosceles trapezoid cross-section. The apparatus has a resonant member having a perimeter at least partially defined by a sidewall slanted at a first angular value and at least one electrode disposed adjacent, and parallel, to the sidewall and separated therefrom by a capacitive gap.
FILED Monday, June 13, 2016
APPL NO 15/743449
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/5642 (20130101)
G01C 19/5747 (20130101) Original (OR) Class

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/241 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/097 (20130101)
G01P 15/125 (20130101)
G01P 2015/0848 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634557 Khorasaninejad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Mohammadreza Khorasaninejad (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts);  Wei Ting Chen (Cambridge, Massachusetts);  Jaewon Oh (Cambridge, Massachusetts)
ABSTRACT A meta-lens having a phase profile includes a substrate and a plurality of nanostructures disposed on the substrate. The nanostructures together define the phase profile of the meta-lens. The phase profile achieves an off-axis focus. Each nanostructure is designed according to at least one design parameter of the nanostructure that imparts a phase shift of light passing through the nanostructure.
FILED Friday, April 07, 2017
APPL NO 16/091976
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/00 (20130101)
G01J 3/18 (20130101)
G01J 3/0208 (20130101) Original (OR) Class
G01J 3/0256 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/08 (20130101)
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634665 Iyer et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Rashi Iyer (Los Alamos, New Mexico);  Jen-Huang Huang (Los Alamos, New Mexico);  Pulak Nath (Los Alamos, New Mexico);  Jennifer Harris (Los Alamos, New Mexico);  John P. Wikswo, Jr. (Brentwood, Tennessee)
ABSTRACT Disclosed herein are embodiments of a device that can be used to mimic the biochemical and physiological actions of a lung organ. Also disclosed herein are embodiments of components that are included in the device as well as methods of making and using the device. Further disclosed are platform device embodiments and various components used therein that can be used in combination with the lung organ devices disclosed herein. In some embodiments, the disclosed devices can be used to determine drug toxicity and also can be used with one or more disease models to determine methods of treating disease.
FILED Thursday, September 24, 2015
APPL NO 15/513949
ART UNIT 1799 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/50273 (20130101)
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 2200/027 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0832 (20130101)
B01L 2300/0887 (20130101)
B01L 2400/0481 (20130101)
B01L 2400/0633 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/06 (20130101)
C12N 5/067 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 7/045 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5008 (20130101)
G01N 33/5014 (20130101)
G01N 33/5064 (20130101) Original (OR) Class
G01N 33/5082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634790 Mullen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Linda Mullen (Chesapeake Beach, Maryland);  Robert Lee (Washington, District of Columbia);  Justin Nash (Leonardtown, Maryland);  Brandon Cochenour (Alexandria, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Linda Mullen (Chesapeake Beach, Maryland);  Robert Lee (Washington, District of Columbia);  Justin Nash (Leonardtown, Maryland);  Brandon Cochenour (Alexandria, Virginia)
ABSTRACT An optical imaging system and method for use in a degraded visual environment is provided. A wideband modulated laser pulse is transmitted from a first location through a medium toward a target object. An input of the transmitted wideband modulated laser pulse is detected by an optical receiver. A target modulated laser pulse, reflected from the target object is detected by the optical receiver. The transmitted and reflected laser pulses are filtered by a bandpass filter, based on a predetermined modulated frequency range. The filtered transmitted and reflected laser pulses are digitized by an analog-digital converter. The digitized transmitted laser pulse is correlated with digitized reflected laser pulse by a digital matched filter, wherein the matched filter produces a passband matched filter output. A range of the target object is determined based on the matched filter output.
FILED Friday, January 13, 2017
APPL NO 15/405993
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/89 (20130101) Original (OR) Class
G01S 17/102 (20130101)

Transmission
H04B 10/5057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634851 Steinbrecher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Gregory R. Steinbrecher (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT A method of nonblocking optical switching includes guiding a first optical beam from a first input to a first output via a first path through an optical switching fabric. The first path traverses a phase shifter disposed between a pair of cascaded Mach-Zehnder interferometers. The method also includes receiving a second optical beam for a second path intersecting with the first path through the optical switching fabric. The method also includes moving the first optical beam from the first path to a third path connecting the first input to the first output without intersecting the second path. The method also includes shifting a phase of the first optical beam, with the phase shifter, while moving the first optical beam from the first path to the third path to prevent the first optical beam from interfering with the second optical beam.
FILED Thursday, May 17, 2018
APPL NO 15/982035
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/356 (20130101) Original (OR) Class
G02B 6/3546 (20130101)
G02B 6/29355 (20130101)

Selecting
H04Q 11/0005 (20130101)
H04Q 2011/0015 (20130101)
H04Q 2011/0035 (20130101)
H04Q 2011/0047 (20130101)
H04Q 2011/0052 (20130101)
H04Q 2011/0058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634938 Fang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusets Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Zhuoran Fang (Foshan, China PRC);  Tian Gu (Fairfax, Virginia);  Juejun Hu (Newton, Massachusetts);  Junying Li (Somerville, Massachusetts);  Yifei Zhang (Cambridge, Massachusetts)
ABSTRACT An alloy of GexSbySezTem includes atoms of Ge, Sb, Se, and Te that form a crystalline structure having a plurality of vacancies randomly distributed in the crystalline structure. The alloy can be used to construct an optical device including a first waveguide to guide a light beam and a modulation layer disposed on the first waveguide. The modulation includes the alloy of GexSbySezTem which has a first refractive index n1 in an amorphous state and a second refractive index n2, greater than the first refractive index by at least 1, in a crystalline state. The first waveguide and the modulation layer are configured to guide about 1% to about 50% of the light beam in the modulation layer when the alloy is in the amorphous state and guide no optical mode when the alloy is in the crystalline state.
FILED Friday, March 30, 2018
APPL NO 15/941879
ART UNIT 2883 — Optics
CURRENT CPC
Alloys
C22C 30/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/0623 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0018 (20130101)
G02F 1/0147 (20130101) Original (OR) Class
G02F 1/225 (20130101)
G02F 2001/212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635490 Bertran Monfort et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Ramon Bertran Monfort (Bronx, New York);  Pradip Bose (Yorktown Heights, New York);  Alper Buyuktosunoglu (White Plains, New York);  Chen-Yong Cher (Port Chester, New York);  Hans M. Jacobson (White Plains, New York);  William J. Song (Atlanta, Georgia);  Karthik V. Swaminathan (Ossining, New York);  Augusto J. Vega (Astoria, New York);  Liang Wang (Charlottesville, Virginia)
ABSTRACT An aspect includes optimizing an application workflow. The optimizing includes characterizing the application workflow by determining at least one baseline metric related to an operational control knob of an embedded system processor. The application workflow performs a real-time computational task encountered by at least one mobile embedded system of a wirelessly connected cluster of systems supported by a server system. The optimizing of the application workflow further includes performing an optimization operation on the at least one baseline metric of the application workflow while satisfying at least one runtime constraint. An annotated workflow that is the result of performing the optimization operation is output.
FILED Tuesday, November 24, 2015
APPL NO 14/950934
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/543 (20130101)
G06F 9/4887 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635761 English et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) ENERGID TECHNOLOGIES CORPORATION (Cambridge, Massachusetts)
ASSIGNEE(S) Energid Technologies Corporation (Cambridge, Massachusetts)
INVENTOR(S) James D. English (Alva, Florida);  Ryan S. Penning (Madison, Wisconsin);  Douglas E. Barker (Somerville, Massachusetts);  James A. Bacon (Bourbonnais, Illinois)
ABSTRACT A method, computer program product, and computer system for configuring a stochastic simulation scenario, wherein the stochastic simulation scenario may include one or more variables without a complete probability distribution. The stochastic simulation scenario may be executed to generate one or more results of the stochastic simulation scenario. At least a portion of the one or more variables without the probability distribution may be optimized using one or more optimization metrics on the one or more results of the stochastic simulation scenario.
FILED Friday, April 29, 2016
APPL NO 15/142157
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/23446 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 2201/0213 (20130101)

Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
G06F 17/5095 (20130101)
G06F 2217/10 (20130101)
G06F 2217/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635971 Chelian et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Inbound, Controlled, Air-Releasable, Unrecoverable Systems (ICARUS)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Suhas E. Chelian (San Jose, California);  Matthias Ziegler (Agoura Hills, California);  James Benvenuto (Beverly Hills, California);  Jeffrey Lawrence Krichmar (Cardiff By the Sea, California);  Randall C. O'Reilly (Boulder, Colorado);  Rajan Bhattacharyya (Sherman Oaks, California)
ABSTRACT Described is a system for proactive and reactive cognitive control using a neural module. The system calculates, for each hypothesis of a set of hypotheses, a probability that an event will occur. The neural module comprises a plurality of neurons and includes the PC module, a prefrontal cortex (PFC) module, an anterior cingulate cortex (ACC) module, a locus coeruleus (LC) module, and a basal forebrain (BF) module. The set of hypotheses are related to tasks to be performed by a plurality of groups, each group having a corresponding hypothesis. For each probability, the system calculates a conflict value across all hypotheses with the ACC module, compares each conflict value to a predetermined threshold using the BF and LC modules. A determination is made whether to directly output the calculated probability or perform an additional probability calculation and output an updated probability.
FILED Tuesday, December 01, 2015
APPL NO 14/955722
ART UNIT 2121 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
G06N 7/005 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635989 Blais et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) SOCPRA Sciences et Génie S.E.C. (Sherbrooke, QC, Canada)
ASSIGNEE(S) SOCPRA Sciences et Génie s.e.c. (Sherbrooke, QC, Canada)
INVENTOR(S) Alexandre Blais (Sherbrooke, Canada);  Baptiste Royer (Sherbrooke, Canada);  Arne Loehre Grimsmo (Sherbrooke, Canada)
ABSTRACT A method and circuit QED implementation of a control-phase quantum logic gate UCP(θ)=diag[1,1,1, e]. Two qubits Qi, two resonators Ra, Rb and a modulator. Q1 and Q2, each has a frequency ωqi and characterized by {circumflex over (σ)}zi. Ra is associated with Q1 and defined by a quantum non-demolition (QND) longitudinal coupling g1z{circumflex over (σ)}1z(â†+â). Rb is integrated into Ra, the QND second longitudinal coupling is defined by Ra as g2z{circumflex over (σ)}2z({circumflex over (b)}†+{circumflex over (b)}) or, when Rb is integrated into Ra, the QND second longitudinal coupling is defined by Ra as g2z{circumflex over (σ)}2z(â†+â) The modulator periodically modulates, at a frequency ωm during a time t, the longitudinal coupling strengths g1z and g2z with respective signals of respective amplitudes {tilde over (g)}1 and {tilde over (g)}2. Selecting a defined value for each of t, g1z and g2z determines θ to specify a quantum logical operation performed by the gate. Q1 and Q2 are decoupled when either one of g1z and g2z is to set to 0.
FILED Thursday, March 09, 2017
APPL NO 16/068199
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Static Stores
G11C 11/44 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/025 (20130101)
H01L 39/223 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636127 Fleizach
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Gregory K. Fleizach (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gregory K. Fleizach (San Diego, California)
ABSTRACT A method and system for bidirectional edge highlighting. A memory receives an original input image. A processor calculates edge intensity for each edge pixel in the original input image. The processor also identifies strong edges and attenuates said strong edges. The processor can further determine whether the attenuated strong edges should be bright or dark based on the intensity of the pixel in the original image. The processor applies bidirectional edge highlighting to the image based on the intensity of the pixel in the original image. The degree of darkness or brightness of the highlighting is based on the calculated edge intensity after strong edge attenuation.
FILED Tuesday, September 25, 2018
APPL NO 16/141398
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 1/20 (20130101)
G06T 5/003 (20130101) Original (OR) Class
G06T 5/30 (20130101)
G06T 7/13 (20170101)
G06T 7/40 (20130101)
G06T 7/136 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636149 Freeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William T. Freeman (Acton, Massachusetts);  Frederic Durand (Somerville, Massachusetts);  Tianfan Xue (Cambridge, Massachusetts);  Michael Rubinstein (Somerville, Massachusetts);  Neal Wadhwa (Mountain View, California)
ABSTRACT An apparatus according to an embodiment of the present invention enables measurement and visualization of a refractive field such as a fluid. An embodiment device obtains video captured by a video camera with an imaging plane. Representations of apparent motions in the video are correlated to determine actual motions of the refractive field. A textured background of the scene can be modeled as stationary, with a refractive field translating between background and video camera. This approach offers multiple advantages over conventional fluid flow visualization, including an ability to use ordinary video equipment outside a laboratory without particle injection. Even natural backgrounds can be used, and fluid motion can be distinguished from refraction changes. Embodiments can render refractive flow visualizations for augmented reality, wearable devices, and video microscopes.
FILED Tuesday, November 21, 2017
APPL NO 15/819791
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/001 (20130101)
G01P 5/26 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/54 (20130101)

Image Data Processing or Generation, in General
G06T 7/20 (20130101) Original (OR) Class
G06T 7/246 (20170101)
G06T 2207/10016 (20130101)
G06T 2207/10021 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/30241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636485 Zehnder et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Daniel M. Zehnder (Los Angeles, California);  Jeong-Sun Moon (Moorpark, California)
ABSTRACT A method for time interleaved writing includes providing a phase change material (PCM) array, the PCM array comprising a plurality of phase change material areas arranged in a two dimensional array having rows and columns, selecting PCM areas to configure, and configuring the selected PCM areas. Selecting PCM areas to configure includes selecting PCM areas to configure in both the row and column dimensions that are separated by at least two PCM areas that are not selected to be configured.
FILED Monday, March 19, 2018
APPL NO 15/925229
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/0004 (20130101)
G11C 13/0069 (20130101) Original (OR) Class
G11C 2213/79 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636654 Xia
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Fengnian Xia (Orange, Connecticut)
ABSTRACT A scalable approach for the synthesis of black phosphorus (BP) material thin films over large areas is described. A red phosphorus (RP) material thin film may be deposited on a substrate followed by conversion to a BP material thin film using high-pressure alone or high pressure and high temperature. A thin-film of dielectric material such as hexagonal boron nitride (hBN) can be formed on a RP material film before the conversion is performed to improve the crystalline quality and stability of the converted BP material. Surprisingly, an atomically sharp and defect-free interface can be formed between the converted BP material and hBN. The BP material has high crystalline uniformity and can be used to fabricate thin-film transistors and optoelectronic devices such as infrared photodetectors.
FILED Friday, April 06, 2018
APPL NO 15/947202
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 25/006 (20130101)
C01B 25/023 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02422 (20130101)
H01L 21/02521 (20130101)
H01L 21/02631 (20130101) Original (OR) Class
H01L 21/6835 (20130101)
H01L 23/3157 (20130101)
H01L 29/26 (20130101)
H01L 29/786 (20130101)
H01L 29/78696 (20130101)
H01L 2221/68304 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636929 McIntosh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) K. Alexander McIntosh (Groton, Massachusetts);  David C. Chapman (Albuquerque, New Mexico);  Joseph P. Donnelly (Carlisle, Massachusetts);  Douglas C. Oakley (Natick, Massachusetts);  Antonio Napoleone (Watertown, Massachusetts);  Erik K. Duerr (Groton, Massachusetts);  Simon Verghese (Arlington, Massachusetts);  Richard D. Younger (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) K. Alexander McIntosh (Groton, Massachusetts);  David C. Chapman (Albuquerque, New Mexico);  Joseph P. Donnelly (Carlisle, Massachusetts);  Douglas C. Oakley (Natick, Massachusetts);  Antonio Napoleone (Watertown, Massachusetts);  Erik K. Duerr (Groton, Massachusetts);  Simon Verghese (Arlington, Massachusetts);  Richard D. Younger (Cambridge, Massachusetts)
ABSTRACT An avalanche photodiode detector is provided with a substrate including an array of avalanche photodiodes. An optical interface surface of the substrate is arranged for accepting external input radiation. There is provided at least one cross-talk blocking layer of material including apertures positioned to allow external input radiation to reach photodiodes and including material regions positioned for attenuating radiation in the substrate that is produced by photodiodes in the array. Alternatively at least one cross-talk blocking layer of material is disposed on the optical interface surface of the substrate to allow external input radiation to reach photodiodes and attenuate radiation in the substrate that is produced by photodiodes in the array. At least one cross-talk filter layer of material can be disposed in the substrate adjacent to the photodiode structures, including a material that absorbs radiation in the substrate that is produced by photodiodes in the array.
FILED Friday, April 30, 2010
APPL NO 12/771155
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 25/167 (20130101)
H01L 27/1446 (20130101)
H01L 31/107 (20130101) Original (OR) Class
H01L 31/0352 (20130101)
H01L 31/02005 (20130101)
H01L 31/02162 (20130101)
H01L 31/02327 (20130101)
H01L 31/03046 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637090 Bond et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Matthew L. Bond (San Diego, California);  Yolanda M. Arias-Thode (San Diego, California);  Kenneth E. Richter (San Diego, California);  David B. Chadwick (San Diego, California);  Lewis Hsu (Honolulu, Hawaii)
ABSTRACT A device for capturing energy, with an anode base, a rigid body, a pressure housing, a cathode array, and a wire. The anode base is connected to the rigid body, the pressure housing is connected to the rigid body, and the cathode array is connected to the rigid body. The first wire is electrically connected to the cathode array. The second wire is electrically connected to the anode base.
FILED Thursday, September 27, 2018
APPL NO 16/143689
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8626 (20130101)
H01M 8/16 (20130101) Original (OR) Class
H01M 8/0247 (20130101)
H01M 8/2475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637586 Zheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Yahong Rosa Zheng (Rolla, Missouri);  Weimin Duan (San Diego, California);  Chengshan Xiao (Rolla, Missouri)
ASSIGNEE(S) National Science Foundation (Alexandria, Virginia)
INVENTOR(S) Yahong Rosa Zheng (Rolla, Missouri);  Weimin Duan (San Diego, California);  Chengshan Xiao (Rolla, Missouri)
ABSTRACT Systems and methods for underwater communication using a MIMO acoustic channel. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder.
FILED Friday, August 25, 2017
APPL NO 15/686390
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Transmission
H04B 11/00 (20130101)
H04B 13/02 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/03057 (20130101)
H04L 27/0008 (20130101)
H04L 2025/03426 (20130101)
H04L 2025/03636 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10638064 Colonero et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Curtis Colonero (Shrewsbury, Massachusetts);  Michael W. Kelly (North Reading, Massachusetts);  Megan H. Blackwell (Winchester, Massachusetts);  Lauren L. White (Burlington, Massachusetts)
ABSTRACT In time-delay-and-integrate (TDI) imaging, a charge-couple device (CCD) integrates and transfers charge across its columns. Unfortunately, the limited well depth of the CCD limits the dynamic range of the resulting image. Fortunately, TDI imaging can be implemented with a digital focal plane array (DFPA) that includes a detector, analog-to-digital converter (ADC), and counter in each pixel and transfer circuitry connected adjacent pixels. During each integration period in the TDI scan, each detector in the DFPA generates a photocurrent that the corresponding ADC turns into digital pulses, which the corresponding counter counts. Between integration periods, the DFPA transfers the counts from one column to the next, just like in a TDI CCD. The DFPA also non-destructively transfers some or all of the counts to a separate memory. A processor uses these counts to estimate photon flux and correct any rollovers caused by “saturation” of the counters.
FILED Wednesday, October 16, 2019
APPL NO 16/654077
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Pictorial Communication, e.g Television
H04N 5/355 (20130101)
H04N 5/378 (20130101)
H04N 5/2355 (20130101)
H04N 5/3743 (20130101)
H04N 5/23254 (20130101)
H04N 5/23267 (20130101)
H04N 5/35554 (20130101) Original (OR) Class
H04N 5/35572 (20130101)
H04N 5/37206 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10638634 Elsasser et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Ryan Elsasser (Poughkeepsie, New York);  William Risk (San Jose, California);  Camillo Sassano (Durham, North Carolina);  Matthew Butterbaugh (Rochester, Minnesota);  Michael Good (Fountain, Minnesota)
ABSTRACT Rack-mountable assemblies are provided which include a cover configured to fixedly mount to a frame of an electronics rack, and a drawer configured to slidably mount to the frame adjacent to the cover to slide relative to the cover. When operatively mounted to the frame, the cover and drawer together define an enclosure for one or more electronic components. The assembly further includes an electromagnetic shielding structure to provide, at least in part, electromagnetic shielding at a gap between the cover and drawer when operatively positioned within the electronics rack. The electromagnetic shielding structure includes an electromagnetic shielding plate which overlies, at least in part, the gap between the cover and the drawer, and which self-adjusts with sliding of the drawer into the electronics rack to facilitate providing the electromagnetic shielding at the gap between the cover and the drawer.
FILED Friday, June 21, 2019
APPL NO 16/448144
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/16 (20130101)
H05K 7/1487 (20130101) Original (OR) Class
H05K 7/1489 (20130101)
H05K 9/0016 (20130101)
H05K 9/0062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10632400 Rudisill et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Tracy S. Rudisill (North Augusta, South Carolina);  Fernando F. Fondeur (North Augusta, South Carolina);  Lindsay E. Roy (Aiken, South Carolina);  William E. Daniel, Jr. (North Augusta, South Carolina)
ABSTRACT The present invention is directed to a method for the separation of an actinide from another metal. The method comprises the following steps: (a) establishing a non-homogeneous magnetic field across a separation column containing a paramagnetic packing material and (b) providing a fluid containing the actinide and the another metal to the separation column wherein the fluid and the paramagnetic packing material are exposed to the non-homogeneous magnetic field. The non-homogeneous magnetic field is produced by a magnet having a first pole for magnetic interaction with a second pole of the magnet wherein the first pole has a different surface area than the second pole. The non-homogeneous magnetic field has a magnetic field gradient of about 500 lines/cm2/cm or more. In addition, the present invention is also directed to a method for the separation of one heavy metal from another heavy metal.
FILED Monday, December 11, 2017
APPL NO 15/837726
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 15/1821 (20130101)
B01D 15/3885 (20130101) Original (OR) Class

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 3/24 (20130101)
C22B 7/005 (20130101)
C22B 59/00 (20130101)
C22B 60/04 (20130101)
C22B 60/0252 (20130101)
C22B 60/0295 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/72 (20130101)

Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 9/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632418 Blencoe et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee);  VIRGINIA MUSEUM OF NATURAL HISTORY FOUNDATION (Martinsville, Virginia)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) James G. Blencoe (Harriman, Tennessee);  Donald A. Palmer (Oliver Springs, Tennessee);  Lawrence M. Anovitz (Knoxville, Tennessee);  James S. Beard (Martinsville, Virginia)
ABSTRACT In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide to produce a hydroxide of the metal formerly contained in the silicate; (b) reacting carbon dioxide with at least one of a caustic alkali-metal hydroxide and an alkali-metal silicate to produce at least one of an alkali-metal carbonate and an alkali-metal bicarbonate; and (c) reacting the metal hydroxide product of step (a) with at least one of the alkali-metal carbonate and the alkali-metal bicarbonate produced in step (b) to produce a carbonate of the metal formerly contained in the metal silicate of step (a).
FILED Wednesday, June 28, 2017
APPL NO 15/635950
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101) Original (OR) Class
B01D 2251/30 (20130101)
B01D 2251/604 (20130101)
B01D 2258/02 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/60 (20170801)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 5/24 (20130101)
C01F 11/18 (20130101)
C01F 11/181 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/04 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/152 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632436 Brown et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Sam W. Brown (Knoxville, Tennessee);  Larry S. Spencer (Knoxville, Tennessee);  Michael R. Phillips (Harriman, Tennessee);  G. Louis Powell (Oak Ridge, Tennessee);  Peggy J. Campbell (Clinton, Tennessee)
ABSTRACT A hydrogen, lithium, and lithium hydride processing apparatus includes a hot zone to heat solid-phase lithium hydride to form liquid-phase lithium hydride; a vacuum source to extract hydrogen and gaseous-phase lithium metal from the liquid-phase lithium hydride; a cold zone to condense the gaseous-phase lithium metal as purified solid-phase lithium metal; and a heater to melt the purified solid-phase lithium metal in the cold zone and form refined liquid-phase lithium metal in the hot zone.
FILED Thursday, May 11, 2017
APPL NO 15/592289
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/002 (20130101)
B01D 53/22 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 7/00 (20130101) Original (OR) Class

Non-metallic Elements; Compounds Thereof;
C01B 3/04 (20130101)

Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 15/00 (20130101)

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 9/04 (20130101)
C22B 9/006 (20130101)
C22B 9/026 (20130101)
C22B 26/12 (20130101)

Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace
F27D 7/06 (20130101)
F27D 17/001 (20130101)
F27D 17/008 (20130101)
F27D 2007/066 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/364 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632447 Liu
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Molecule Works Inc. (Richland, Washington)
ASSIGNEE(S) Molecule Works Inc. (Richland, Washington)
INVENTOR(S) Wei Liu (Richland, Washington)
ABSTRACT Design, fabrication, and usage of a reactor are presented for synthesis of structured materials from a liquid-phase precursor by heating. The structured materials are particles, membranes or films of micro-porous molecular sieve crystals such as zeolite and meso-porous materials. The precursor solution and structured materials in the reactor are uniformly heated by a planar heater with characteristic heat transfer dimension in the range of 3 mm to 10 cm. A planar heater having width and length at least three times of the characteristic heat transfer dimension provides at least one surface of uniform temperature distribution for heating purposes. Heating is conducted over a temperature range of 20 to 300° C. The planar heater can be heated by electrical power of by thermal fluid.
FILED Friday, December 28, 2018
APPL NO 16/235655
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 67/0051 (20130101)
B01D 69/10 (20130101)
B01D 71/028 (20130101)
B01D 2323/08 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 3/04 (20130101)
B01J 19/247 (20130101) Original (OR) Class
B01J 2219/00058 (20130101)
B01J 2219/00081 (20130101)
B01J 2219/00096 (20130101)
B01J 2219/00162 (20130101)
B01J 2219/1943 (20130101)
B01J 2219/2486 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633255 Campbell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Patrick G. Campbell (Oakland, California);  Theodore F. Baumann (Discovery Bay, California);  Juergen Biener (San Leandro, California);  Matthew Merrill (Dublin, California);  Elizabeth Montalvo (Oakland, California);  Marcus Worsley (Hayward, California);  Monika M. Biener (San Leandro, California);  Maira Raquel Ceron Hernandez (Livermore, California)
ABSTRACT Disclosed here is a method for producing a graphene macro-assembly (GMA)-fullerene composite, comprising providing a GMA comprising a three-dimensional network of graphene sheets crosslinked by covalent carbon bonds, and incorporating at least 20 wt. % of at least one fullerene compound into the GMA based on the initial weight of the GMA to obtain a GMA-fullerene composite. Also described are a GMA-fullerene composite produced, an electrode comprising the GMA-fullerene composite, and a supercapacitor comprising the electrode and optionally an organic or ionic liquid electrolyte in contact with the electrode.
FILED Monday, November 06, 2017
APPL NO 15/805010
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/156 (20170801)
C01B 32/194 (20170801) Original (OR) Class

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/32 (20130101)
H01G 11/36 (20130101)
H01G 11/38 (20130101)
H01G 11/68 (20130101)
H01G 11/70 (20130101)
H01G 11/86 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/133 (20130101)
H01M 4/364 (20130101)
H01M 4/587 (20130101)
H01M 4/1393 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/738 (20130101)
Y10S 977/896 (20130101)
Y10S 977/948 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633332 Custelcean et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Radu Custelcean (Beavercreek, Ohio);  Charles A. Seipp (Beavercreek, Ohio);  Neil J. Williams (Knoxville, Tennessee)
ABSTRACT Methods for removing oxyanions from water according to the following steps: (i) dissolving an oxyanion precipitating compound into the aqueous source to result in precipitation of an oxyanion salt of the oxyanion precipitating compound; and (ii) removing the oxyanion salt from the water containing the oxyanion to result in water substantially reduced in concentration of the oxyanion; wherein the oxyanion precipitating compound has the following composition:
wherein A is a ring-containing moiety and Xm− is an anionic species with a magnitude of charge m. The invention employs bis-iminoguanidinium compounds according to Formula (1a) as well as neutral precursor compounds according to Formula (1), which can be used for removing undesirable species from aqueous solutions or air, such as removal of sulfate from water and carbon dioxide from air.
FILED Thursday, September 13, 2018
APPL NO 16/129979
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Separation
B01D 53/1425 (20130101)
B01D 53/1475 (20130101)
B01D 53/1493 (20130101)
B01D 2252/20415 (20130101)
B01D 2252/20421 (20130101)
B01D 2252/20426 (20130101)
B01D 2252/20431 (20130101)
B01D 2252/20457 (20130101)
B01D 2252/20494 (20130101)
B01D 2258/06 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/5272 (20130101)
C02F 2101/101 (20130101)
C02F 2101/103 (20130101)
C02F 2101/105 (20130101)
C02F 2103/08 (20130101)

Acyclic or Carbocyclic Compounds
C07C 279/12 (20130101) Original (OR) Class
C07C 281/18 (20130101)
C07C 2601/16 (20170501)

Heterocyclic Compounds
C07D 207/335 (20130101)
C07D 213/00 (20130101)
C07D 213/53 (20130101)
C07D 239/26 (20130101)
C07D 241/12 (20130101)
C07D 307/52 (20130101)
C07D 333/22 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/06 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/346 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/152 (20151101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 10/37 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633592 Henry et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Asegun Henry (Atlanta, Georgia);  Caleb Amy (Atlanta, Georgia);  Malavika Bagepalli (Atlanta, Georgia);  Daniel Budenstein (Atlanta, Georgia)
ABSTRACT An exemplary embodiment of the present invention provides a reactor system comprising: a reaction vessel comprising a reactant, a heat transfer fluid and a first reaction product, wherein the heat transfer fluid has a greater density than the first reaction product such that at least a portion of the first reaction product floats on a surface of the heat transfer fluid; a first outlet positioned at a surface level of the first reaction product, the first outlet configured to output a first outlet flow comprising at least a portion of the first reaction product and at least a portion of the heat transfer fluid; wherein the heat transfer fluid is configured to provide thermal energy to the reactant in the reaction vessel to form the first reaction product.
FILED Tuesday, October 31, 2017
APPL NO 15/799280
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/24 (20130101)
C01B 2203/1241 (20130101)

Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials
C10B 49/14 (20130101) Original (OR) Class

Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases
C10J 3/57 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/39 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633668 Kaeppler et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Shawn Kaeppler (Oregon, Wisconsin);  Natalia de Leon Gatti (Middleton, Wisconsin);  Jillian Foerster (Madison, Wisconsin)
ABSTRACT The present invention relates to compositions and methods for modulating the juvenile to adult developmental growth transition in plants, such as grasses (e.g. maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G362718, GRMZM2G096016, or homologs thereof. Modulation of expression of one or more additional genes which affect juvenile to adult developmental growth transition such as Glossy15 or Cg1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G362718 and/or GRMZM2G096016 are also contemplated, as are transgenic plants and products produced there from, that demonstrate altered, such as extended juvenile growth, and display associated phenotypes such as enhanced yield, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production.
FILED Friday, April 07, 2017
APPL NO 15/482588
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8261 (20130101)
C12N 15/8266 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633722 Braydich et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) GDC Industries, LLC (Dayton, Ohio)
ASSIGNEE(S) GDC Industries, LLC (Dayton, Ohio)
INVENTOR(S) Michael Dennis Braydich (Beavercreek, Ohio);  Harry Couch (Beavercreek, Ohio);  Louis A. Luedtke (Centerville, Ohio)
ABSTRACT There are provided methods and systems for creating multi-phase covetics. For example, there is provided a process for making a composite material. The process includes forming a multi-phase covetic. The forming includes heating a melt including a metal in a molten state and a carbon source to a first temperature threshold to form metal-carbon bonds. The forming further includes subsequently heating the melt to a second temperature threshold, the second temperature threshold being greater than the first temperature threshold. The second temperature threshold is a temperature at or above which ordered multi-phase covetics form in the melt.
FILED Monday, September 10, 2018
APPL NO 16/126111
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 1/02 (20130101)
C22C 1/026 (20130101) Original (OR) Class
C22C 1/1036 (20130101)
C22C 21/00 (20130101)
C22C 26/00 (20130101)
C22C 2026/001 (20130101)
C22C 2026/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633723 Braydich et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) GDC Industries, LLC (Dayton, Ohio)
ASSIGNEE(S) GDC Industries, LLC (Dayton, Ohio)
INVENTOR(S) Michael Dennis Braydich (Beavercreek, Ohio);  Harry Couch (Beavercreek, Ohio);  Louis A. Luedtke (Centerville, Ohio)
ABSTRACT There are provided methods and systems for creating multi-phase covetics. For example, there is provided a process for making a composite material. The process includes forming a multi-phase covetic. The forming includes heating a melt including a metal in a molten state and a carbon source to a first temperature threshold to form metal-carbon bonds. The forming further includes subsequently heating the melt to a second temperature threshold, the second temperature threshold being greater than the first temperature threshold. The second temperature threshold is a temperature at or above which ordered multi-phase covetics form in the melt.
FILED Monday, September 10, 2018
APPL NO 16/126166
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 1/02 (20130101)
C22C 1/026 (20130101) Original (OR) Class
C22C 1/1036 (20130101)
C22C 21/00 (20130101)
C22C 26/00 (20130101)
C22C 2026/001 (20130101)
C22C 2026/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633750 Tessonnier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa States University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Jean-Philippe Tessonnier (Ames, Iowa);  John Edward Matthiesen (Ames, Iowa);  Nacu B. Hernandez-Cantu (Ames, Iowa);  Eric W. Cochran (Ames, Iowa)
ABSTRACT Various embodiments disclosed relate to electrocatalytic hydrogenation of muconic acid and polymers formed from the reaction products thereof. In various embodiments, the present invention provides an electrocatalytic method to prepare 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a combination thereof, from muconic acid. The method includes passing current through a catalytic cathode in a reactor including an aqueous acidic solution including muconic acid, a supporting electrolyte, and an anode, so as to generate atomic hydrogen on the cathode surface in an amount effective to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. Also disclosed is the polymerization of 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, or a combination thereof with another compound, such as a diamine or a dialcohol, to form a polymer, such as a polyamide or a polyester.
FILED Tuesday, November 10, 2015
APPL NO 15/524888
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/16 (20130101)
C08G 69/26 (20130101)
C08G 69/28 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633985 Garcia-Crespo et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Andrés Jose Garcia-Crespo (Greenville, South Carolina);  Patrick Daniel Noble (Greenville, South Carolina)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Andrés Jose Garcia-Crespo (Greenville, South Carolina);  Patrick Daniel Noble (Greenville, South Carolina)
ABSTRACT A system includes a blade segment having a blade and a mounting segment coupled to the blade. Additionally, the mounting segment includes a first contact face and a second contact face, wherein the first and second contact face are concave with respect to a longitudinal axis of the blade segment. To reduce stresses within the mounting segment, the mounting segment further includes a lower face coupling the first contact face and the second contact face, wherein the lower face is convex across the longitudinal axis of the blade segment.
FILED Monday, June 25, 2012
APPL NO 13/532713
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/30 (20130101)
F01D 5/284 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/71 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/672 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634012 Tricaud et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S) Cummins Inc. (Columbus, Indiana)
INVENTOR(S) Christophe Tricaud (Columbus, Indiana);  James A. Zigan (Versailles, Indiana)
ABSTRACT An apparatus includes a pump circuit structured to receive pump data indicative of an operating characteristic of a pump feeding a fluid to a waste heat recovery (WHR) system; a flow circuit structured to receive valve position data indicative of a position of a valve downstream of the pump, estimate a flow rate of the fluid exiting the pump, and estimate the flow rate of the fluid exiting the valve; and a pressure circuit structured to receive pressure data indicative of the pressure of the fluid exiting the valve, estimate a change in pressure of the fluid across the WHR system, and determine a pressure of the fluid in a hot section of the WHR system based on the pressure of the fluid exiting the valve and the change in the pressure of the fluid across the WHR system.
FILED Friday, May 10, 2019
APPL NO 16/409193
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 13/02 (20130101)
F01K 23/065 (20130101) Original (OR) Class
F01K 27/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634398 van Hassel et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Carrier Corporation (Palm Beach Gardens, Florida)
ASSIGNEE(S) CARRIER CORPORATION (Palm Beach Gardens, Florida)
INVENTOR(S) Bart Antonie van Hassel (Weatogue, Connecticut);  Abdelrahman Elsherbini (Windsor, Connecticut);  Thomas D. Radcliff (Vernon, Connecticut);  Parmesh Verma (South Windsor, Connecticut)
ABSTRACT A heating, ventilation, air conditioning and refrigeration (HVAC/R) system includes a sorption circuit including a heat absorption heat exchanger in fluid communication with a primary fluid flow source such that a primary fluid flow from is directed therethrough. The heat absorption heat exchanger is configured to exchange thermal energy between the primary fluid flow and a secondary fluid flow. A sorption heat exchanger includes a sorbent material to adsorb or absorb the primary fluid flow, generating thermal energy. The sorption heat exchanger is configured to transfer the generated thermal energy to a tertiary fluid flow. A heat exchange circuit is in fluid communication with the sorption circuit and includes a control valves connected to both the secondary fluid flow and the tertiary fluid flow configured to selectably direct the secondary fluid flow and/or the tertiary fluid flow to a conditioning heat exchanger or an ambient heat exchanger.
FILED Tuesday, October 18, 2016
APPL NO 16/063512
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 5/0014 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 17/00 (20130101)
F25B 25/02 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 30/276 (20180101)
Y02A 30/277 (20180101)
Y02A 30/278 (20180101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 30/62 (20130101)
Y02B 30/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634445 Klett
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) James W. Klett (Knoxville, Tennessee)
ABSTRACT Disclosed are several examples of suppressors for not only suppressing the blast and flash produced as a projectile is expelled from a firearm, but also reduces backpressure and heat absorbed by the suppressors during each shot.
FILED Wednesday, June 12, 2019
APPL NO 16/438964
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 21/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634665 Iyer et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Rashi Iyer (Los Alamos, New Mexico);  Jen-Huang Huang (Los Alamos, New Mexico);  Pulak Nath (Los Alamos, New Mexico);  Jennifer Harris (Los Alamos, New Mexico);  John P. Wikswo, Jr. (Brentwood, Tennessee)
ABSTRACT Disclosed herein are embodiments of a device that can be used to mimic the biochemical and physiological actions of a lung organ. Also disclosed herein are embodiments of components that are included in the device as well as methods of making and using the device. Further disclosed are platform device embodiments and various components used therein that can be used in combination with the lung organ devices disclosed herein. In some embodiments, the disclosed devices can be used to determine drug toxicity and also can be used with one or more disease models to determine methods of treating disease.
FILED Thursday, September 24, 2015
APPL NO 15/513949
ART UNIT 1799 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/50273 (20130101)
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 2200/027 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0832 (20130101)
B01L 2300/0887 (20130101)
B01L 2400/0481 (20130101)
B01L 2400/0633 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/06 (20130101)
C12N 5/067 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 7/045 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5008 (20130101)
G01N 33/5014 (20130101)
G01N 33/5064 (20130101) Original (OR) Class
G01N 33/5082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634732 Warmack et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Robert J. Warmack (Oak Ridge, Tennessee);  Milton Nance Ericson (Oak Ridge, Tennessee);  Roger A. Kisner (Oak Ridge, Tennessee);  Yarom Polsky (Oak Ridge, Tennessee)
ABSTRACT A system and method verifies continuity with and measures voltage across a circuit under test (in some instances simultaneously) using two or more test probes. Two or more probe continuity circuits measure continuity through the test probes by injecting a test current through and measuring a processed test current received at each of the plurality of test probes. The probe continuity circuits measure the respective processed test current rendered by the test current flowing through the test circuit at each test probe. A voltmeter measures the potential difference across the test probes.
FILED Friday, August 11, 2017
APPL NO 15/675456
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/073 (20130101)
G01R 1/06722 (20130101)
G01R 31/50 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635403 Pooser et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Raphael C. Pooser (Knoxville, Tennessee);  Benjamin J. Lawrie (Oak Ridge, Tennessee);  Bing Qi (Knoxville, Tennessee);  Brian P. Williams (Knoxville, Tennessee)
ABSTRACT A system and method are provided to yield a QRNG based on homodyne detection of quantum noise (e.g., vacuum noise measured as shot noise) generated from a local oscillator, such as an LED. In one embodiment, a QRNG may be provided that is adjustable based on a control input to produce a random output that can be translated to one or more random data bits.
FILED Wednesday, September 26, 2018
APPL NO 16/142984
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/0425 (20130101)

Electric Digital Data Processing
G06F 7/58 (20130101)
G06F 7/588 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635588 Eckert et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S) Yasuko Eckert (Bellevue, Washington);  Maurice B. Steinman (Boxborough, Massachusetts);  Steven Raasch (Boxborough, Massachusetts)
ABSTRACT A processing system includes a first set of one or more processing units including a first processing unit, a second set of one or more processing units including a second processing unit, and a memory having an address space shared by the first and second sets. The processing system further includes a distributed coherence directory subsystem having a first coherence directory to support a first subset of one or more address regions of the address space and a second coherence directory to support a second subset of one or more address regions of the address space. In some implementations, the first coherence directory is implemented in the system so as to have a lower access latency for the first set, whereas the second coherence directory is implemented in the system so as to have a lower access latency for the second set.
FILED Tuesday, June 05, 2018
APPL NO 16/000199
ART UNIT 2139 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/084 (20130101)
G06F 12/0824 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635985 Gauthier et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  INTERA Incorporated (Austin, Texas)
INVENTOR(S) John H. Gauthier (Albuquerque, New Mexico);  Nadine E. Miner (Albuquerque, New Mexico);  Michael L. Wilson (Albuquerque, New Mexico);  Dennis E. Longsine (Leander, Texas)
ABSTRACT Methods, systems and computer program products to measure system re-taskability are disclosed. The methods, systems and computer program products may be used in the design of a new or redesign of an existing System of Systems (SoS). Systems re-tasking (aka substitutability or stand-in redundancy) is the process of using different systems to substitute for non-operational systems to meet required functionality, or using multi-function systems to fulfill higher-priority tasks. This ability can increase the overall operational availability of the SoS; it can also increase the adaptability and resilience of the SoS to unknown or changing conditions. The disclosed methods, systems and computer products include simulating an SoS over time, replacing systems that become non-operational (or damaged) with systems that can fulfill the same capability in order to maximize the SoS availability.
FILED Wednesday, October 22, 2014
APPL NO 14/521285
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 7/00 (20130101) Original (OR) Class
G06N 20/00 (20190101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/067 (20130101)
G06Q 10/0637 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636533 Lordi et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Vincenzo Lordi (Livermore, California);  Patrice Erne A. Turchi (Menlo Park, California)
ABSTRACT In one embodiment, an alloy includes: Zr; Fe; Cu; Ta in an amount from about 1 wt % to about 3 wt %; and one or more optional constituents selected from: Ti, Be, and Nb; and wherein the alloy comprises a ductile phase and a nanoprecipitate hard phase. According to another embodiment, a method of forming an inert matrix nuclear fuel includes: packing a hollow structure with fuel pellets and alloy precursor pellets; heating the fuel pellets and the alloy precursor pellets to at least a melting temperature of an alloy to be formed by melting the alloy precursor pellets; and solidifying the alloy into a matrix surrounding the fuel pellets. The alloy precursor pellets independently comprise: Zr; Fe; Cu; Ta present in an amount from about 1 to about 3 wt %; and one or more optional alloy constituents selected from: Ti, Be, and Nb.
FILED Thursday, November 10, 2016
APPL NO 15/348885
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Alloys
C22C 16/00 (20130101)

Nuclear Reactors
G21C 3/20 (20130101)
G21C 3/28 (20130101)
G21C 3/60 (20130101)
G21C 21/02 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636632 Hilt et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Florian Hilt (San Jose, California);  Michael Q. Hovish (Mountain View, California);  Nicholas Rolston (Stanford, California);  Reinhold H. Dauskardt (Menlo Park, California)
ABSTRACT Improved deposition of optoelectronically active perovskite materials is provided with a two step process. In the first step, precursors are deposited on a substrate. In the second step, the deposited precursors are exposed to an atmospheric pressure plasma which efficiently cures the precursors to provide the desired perovskite thin film. The resulting films can have excellent optical properties combined with superior mechanical properties.
FILED Thursday, January 18, 2018
APPL NO 15/874527
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/32055 (20130101)
H01J 37/32073 (20130101)
H01J 37/32192 (20130101)
H01J 37/32348 (20130101)
H01J 37/32825 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/032 (20130101)
H01L 31/186 (20130101)
H01L 31/1872 (20130101)
H01L 33/0095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636920 Spagnola et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Joseph C. Spagnola (Woodbury, Minnesota);  Mark A. Roehrig (Stillwater, Minnesota);  Thomas P. Klun (Lakeland, Minnesota);  Alan K. Nachtigal (Minneapolis, Minnesota);  Jennifer K. Schnobrich (St. Paul, Minnesota);  Guy D. Joly (Shoreview, Minnesota)
ABSTRACT A barrier film that includes a substrate, a first polymer layer on a major surface of the substrate, an oxide layer on the first polymer layer, and a second polymer layer on the oxide layer. At least one of the first or second polymer layers includes a siloxane reaction product of a secondary or tertiary amino-functional silane having at least two silane groups. A method of making the barrier film and articles and a barrier assembly including the barrier film are also disclosed.
FILED Thursday, August 08, 2013
APPL NO 14/420060
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/60 (20130101)
B05D 7/04 (20130101)
B05D 7/56 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/12 (20130101)
B32B 27/08 (20130101)
B32B 27/30 (20130101)
B32B 27/36 (20130101)
B32B 27/281 (20130101)
B32B 27/283 (20130101)
B32B 27/286 (20130101)
B32B 27/288 (20130101)
B32B 27/308 (20130101)
B32B 33/00 (20130101)
B32B 2307/554 (20130101)
B32B 2307/558 (20130101)
B32B 2307/584 (20130101)
B32B 2307/712 (20130101)
B32B 2307/7244 (20130101)
B32B 2307/7246 (20130101)
B32B 2307/7248 (20130101)
B32B 2457/00 (20130101)
B32B 2457/12 (20130101)
B32B 2457/20 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 7/045 (20130101)
C08J 2367/02 (20130101)
C08J 2433/14 (20130101)
C08J 2483/04 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 183/04 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/133305 (20130101)
G02F 2001/133337 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02167 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 428/3154 (20150401)
Y10T 428/31544 (20150401)
Y10T 428/31547 (20150401)
Y10T 428/31663 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636974 Campos et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  BROOKHAVEN SCIENCE ASSOCIATES, LLC. (Upton, New York)
INVENTOR(S) Luis Miguel Campos (Brooklyn, New York);  Matthew Y. Sfeir (Bethpage, New York);  Jianlong Xia (New York, New York);  Erik Michael Allan Busby (Patchogue, New York);  Jonathan Zhaozhi Low (New York, New York)
ABSTRACT Embodiments of the present invention provides compounds, compositions, and methods for their preparation that provide efficient intramolecular fission, such that local order and strong nearest neighbor coupling is no longer a design constraint. Inventive materials include organic oligomers and polymers designed to exhibit strong intrachain donor-acceptor interactions and provide intramolecular singlet fission, whereby triplet populations can be generated in very high yields of, e.g., 170% or more. The inventive disclosure is directed to polymers of the general formula: [SA-SD]n with a strong electron acceptor (SA), a strong electron donor (SD), and n a positive integer equal to or greater than two; methods for their preparation and monomers used therein, blends, mixtures and formulations containing them; the use of the polymers, blends, mixtures and formulations as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations.
FILED Monday, October 24, 2016
APPL NO 15/333043
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101)
C08G 2261/18 (20130101)
C08G 2261/91 (20130101)
C08G 2261/124 (20130101)
C08G 2261/228 (20130101)
C08G 2261/334 (20130101)
C08G 2261/344 (20130101)
C08G 2261/414 (20130101)
C08G 2261/514 (20130101)
C08G 2261/1412 (20130101)
C08G 2261/1424 (20130101)
C08G 2261/3223 (20130101)
C08G 2261/3243 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0036 (20130101) Original (OR) Class
H01L 51/42 (20130101)
H01L 51/0043 (20130101)
H01L 51/0558 (20130101)
H01L 51/4253 (20130101)
H01L 51/5012 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637011 Pozin et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware)
INVENTOR(S) Michael Pozin (Brookfield, Connecticut);  Walter Fred Paxton (Albuquerque, New Mexico)
ABSTRACT A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state.
FILED Tuesday, August 15, 2017
APPL NO 15/677921
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/028 (20130101)
H01M 2/30 (20130101)
H01M 2/34 (20130101)
H01M 2/0222 (20130101)
H01M 2/0267 (20130101)
H01M 2/0287 (20130101) Original (OR) Class
H01M 2/0292 (20130101)
H01M 10/0427 (20130101)
H01M 2200/00 (20130101)
H01M 2220/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637022 Lampe-Onnerud et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
ASSIGNEE(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
INVENTOR(S) Maria Christina Lampe-Onnerud (Wilton, Connecticut);  Tord Per Jens Onnerud (Wilton, Connecticut);  Jay Jie Shi (Acton, Massachusetts);  Michael Suba (Sandy Hook, Connecticut);  Joshua Liposky (Seymour, Connecticut)
ABSTRACT A multi-core lithium ion battery includes a sealed enclosure and a support member disposed within the sealed enclosure. The sealed enclosure may further include at least two support members housed within individual compartments, separated by shared wall(s). The support member(s) includes a plurality of cavities and a plurality of lithium ion core members which are disposed within the plurality of cavities. The battery may further include a plurality of cavity liners, each of which is positioned between a corresponding one of the lithium ion core members and a surface of a corresponding one of the cavities. The hermetically sealed enclosure may be formed using a clamshell configuration. Structures may be included in proximity to or in contact with the lithium ion core members to control gas/fluid flow therefrom.
FILED Wednesday, December 13, 2017
APPL NO 15/840162
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/34 (20130101)
H01M 2/0242 (20130101)
H01M 2/347 (20130101)
H01M 2/1016 (20130101)
H01M 2/1027 (20130101)
H01M 2/1077 (20130101) Original (OR) Class
H01M 2/1094 (20130101)
H01M 2/1686 (20130101)
H01M 4/366 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/5825 (20130101)
H01M 10/0525 (20130101)
H01M 10/0567 (20130101)
H01M 16/00 (20130101)
H01M 2010/4271 (20130101)
H01M 2200/00 (20130101)
H01M 2200/103 (20130101)
H01M 2220/10 (20130101)
H01M 2220/20 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637072 Stamenkovic et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Vojislav Stamenkovic (Naperville, Illinois);  Gregory K. Krumdick (Homer Glen, Illinois);  Rongyue Wang (Naperville, Illinois);  Nenad Markovic (Hinsdale, Illinois);  Krzysztof Pupek (Plainfield, Illinois);  Trevor L. Dzwiniel (Carol Stream, Illinois)
ABSTRACT A method for synthesis of PtNi nanocages by synthesizing Pt1Ni6 nanoparticles and acid leaching to form PtNi nanocages. The acid leaching removes nickel selectively from the core of the nanoparticle.
FILED Tuesday, June 12, 2018
APPL NO 16/006671
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/921 (20130101) Original (OR) Class
H01M 4/9091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637099 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Lu Zhang (Lisle, Illinois);  Jingjing Zhang (Willowbrook, Illinois);  Ilya A. Shkrob (Chicago, Illinois);  Zhengcheng Zhang (Naperville, Illinois)
ABSTRACT An electrolyte for a lithium-ion electrochemical cell comprises a non-aqueous solution of a lithium salt and a redox shuttle compound, wherein the redox shuttle compound comprises —OR groups at carbons 1 and 4 of a benzene ring; a first hydrocarbon ring fused to carbons 2 and 3 of the benzene ring; and a second hydrocarbon ring fused to the carbons 5 and 6 of the benzene ring, wherein either (i) the first and second hydrocarbon rings together with the benzene ring constitute two fused benzobicyclo[2.2.2]octane ring systems sharing a common benzo core group; or (ii) the first and second hydrocarbon rings together with the benzene ring constitute two fused benzobicyclo[2.2.1]heptane ring systems sharing a common benzo core group.
FILED Wednesday, May 17, 2017
APPL NO 15/597381
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 2300/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637100 Armstrong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Beth L. Armstrong (Oak Ridge, Tennessee);  Gabriel M. Veith (Knoxville, Tennessee);  Sergiy Kalnaus (Knoxville, Tennessee);  Hsin Wang (Knoxville, Tennessee);  Katie L. Browning (Oak Ridge, Tennessee);  Kevin M. Cooley (Knoxville, Tennessee)
ABSTRACT A method of making a passively impact resistant composite electrolyte and separator layer includes providing a suspension composition including electrically non-conducting particles that enable shear thickening. The particles can have a polydispersity index of no greater than 0.1, an average particle size in a range of from 50 nm to 1 um, and an absolute zeta potential of greater than ±40 mV. A particle suspension solvent is provided for suspending the particles. The suspension composition is applied to a porous separator material. A portion of the particles and suspension solvent penetrate the pores and the remainder of the particles in the suspension composition are distributed across the surface of the separator material. The suspension solvent is evaporated from the separator material to provide a shear thickening particle loaded separator. A separator assembly and a passivated battery are also disclosed.
FILED Friday, April 20, 2018
APPL NO 15/958446
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 41/88 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/052 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 2300/0028 (20130101)
H01M 2300/0085 (20130101)
H01M 2300/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637293 Costinett et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Daniel Jes Costinett (Knoxville, Tennessee);  Chongwen Zhao (Knoxville, Tennessee)
ABSTRACT A transmitter for wireless power transfer is provided. The transmitter includes an input port, a first transmission port, a second transmission port, an inverter, and a controller. An input of the inverter is coupled to the input port, and an output of the inverter is coupled in parallel to the first and second transmission ports. The controller is programmed to control the inverter to modulate an output voltage at the output of the inverter such that power from the input port is transmitted at a first frequency through the first transmission port and at a second frequency through the second transmission port.
FILED Thursday, September 28, 2017
APPL NO 15/718767
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/12 (20160201) Original (OR) Class
H02J 50/40 (20160201)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/33561 (20130101)
H02M 7/53871 (20130101)
H02M 2007/4815 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/1441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637744 Carroll et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Thomas E. Carroll (Richland, Washington);  Satish Chikkagoudar (Richland, Washington);  Kristine M. Arthur-Durett (Richland, Washington);  Dennis G. Thomas (Kennewick, Washington)
ABSTRACT A network analysis tool evaluates network flow information in complementary workflows to identify one-hop behavior of network assets and also identify multi-hop dependencies between network assets. In one workflow (e.g., using association rule learning), the network analysis tool can identify significant one-hop communication patterns to and/or from network assets, taken individually. Based on the identified one-hop behavior, the network analysis tool can discover patterns of similar communication among different network assets, which can inform decisions about deploying patch sets, mitigating damage, configuring a system, or detecting anomalous behavior. In a different workflow (e.g., using deep learning or cross-correlation analysis), the network analysis tool can identify significant multi-hop communication patterns that involve network assets in combination. Based on the identified multi-hop dependencies, the network analysis tool can discover functional relationships between network assets, which can inform decisions about configuring a system, managing critical network assets, or protecting critical network assets.
FILED Wednesday, April 12, 2017
APPL NO 15/486162
ART UNIT 2445 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/14 (20130101)
H04L 41/16 (20130101) Original (OR) Class
H04L 43/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637785 Lyle et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Joshua A. Lyle (Chicago, Illinois);  Nathaniel Evans (Orland Hills, Illinois)
ABSTRACT Systems, methods, and storage media for utilizing software defined networking for a multiple operating system rotational environment, executing on a computing device are disclosed. Some implementations may: receive a request from a user device; modify a packet of the request with a destination address and a port of a first server; forward the modified packet of the request to a controller server; receive a flow modification from the controller server based on the modified packet; and modify further received packets from the user device based on the received flow modification.
FILED Thursday, August 16, 2018
APPL NO 15/998485
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/38 (20130101)
H04L 45/64 (20130101)
H04L 47/2458 (20130101)
H04L 47/2466 (20130101) Original (OR) Class
H04L 47/2483 (20130101)
H04L 49/254 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE47965 Liszkai et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S) NUSCALE POWER LLC (Portland, Oregon)
INVENTOR(S) Tamas Liszkai (Corvallis, Oregon);  Seth Cadell (Corvallis, Oregon)
ABSTRACT A system for attenuating seismic forces includes a reactor pressure vessel containing nuclear fuel and a containment vessel that houses the reactor pressure vessel. Both the reactor pressure vessel and the containment vessel include a bottom head. Additionally, the system includes a base support to contact a support surface on which the containment vessel is positioned in a substantially vertical orientation. An attenuation device is located between the bottom head of the reactor pressure vessel and the bottom head of the containment vessel. Seismic forces that travel from the base support to the reactor pressure vessel via the containment vessel are attenuated by the attenuation device in a direction that is substantially lateral to the vertical orientation of the containment vessel.
FILED Tuesday, April 24, 2018
APPL NO 15/961804
ART UNIT 3993 — Central Reexamination Unit (Mechanical)
CURRENT CPC
Nuclear Reactors
G21C 1/322 (20130101)
G21C 5/10 (20130101)
G21C 9/04 (20130101) Original (OR) Class
G21C 13/024 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10631475 Goldberg et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ken Goldberg (Mill Valley, California);  Stefano Carpin (Santa Cruz, California);  Stephen McKinley (Berkeley, California);  Stavros Vougioukas (Davis, California);  David Gealy (Arroyo Grande, California)
ABSTRACT According to some embodiments of the invention, an adjusting device for adjusting a passive drip irrigation valve to enable precision irrigation includes a device body configured to be at least one of hand-held or attachable to a robot, the device body having a manipulator end, and a manipulator assembly contained within and extending from the manipulator end of the device body. The manipulator assembly includes a coarse alignment adjustment assembly constructed and arranged to align the adjusting device with the passive drip irrigation valve. The manipulator assembly also includes a fine actuator configured to rotate the passive drip irrigation valve by a specified angle.
FILED Thursday, August 11, 2016
APPL NO 15/752474
ART UNIT 2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 25/02 (20130101)
A01G 25/16 (20130101) Original (OR) Class

Manipulators; Chambers Provided With Manipulation Devices
B25J 5/007 (20130101)
B25J 11/00 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 47/045 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/00 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/106 (20130101)
G05B 2219/2625 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/028 (20130101)
G05D 1/0246 (20130101)
G05D 1/0282 (20130101)
G05D 2201/0201 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10415 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/237 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632206 Emrick et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Todd Emrick (South Deerfield, Massachusetts);  Xiangji Chen (Woodbury, Minnesota);  Samantha Page (Goleta, California)
ABSTRACT The invention generally relates to zwitterionic polymers (including zwitterionic copolymers), such as polymethacrylic structures, with pendent functional moieties, such as therapeutic or biologic moieties. More particularly, the invention relates to phosphorylcholine-substituted methacrylic polymers prepared by free radical polymerization and click chemistry, for example, and compositions and products comprising same, as well as related methods and uses of the compositions, for example, as biological or therapeutic agents and in drug delivery thereof.
FILED Thursday, June 30, 2016
APPL NO 15/198372
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 31/4745 (20130101)
A61K 47/58 (20170801)
A61K 47/48176 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 220/10 (20130101)
C08F 220/34 (20130101)
C08F 230/02 (20130101)
C08F 238/00 (20130101)
C08F 293/005 (20130101)
C08F 2438/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10632585 Greenslet
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Hitomi Greenslet (Gainesville, Florida)
ABSTRACT Various examples are provided for hybrid tools including fixed-abrasive and loose-abrasive phases. In one example, a hybrid tool for finishing an internal surface of a workpiece includes a metallic rod and magnetic abrasive bonded to one or more defined portions of the metallic rod by an adhesive that dissolves when n contact with a lubricant used to finish the internal surface of the workpiece. In another example, a method for finishing an internal surface of a workpiece includes mounting the workpiece in a chuck of a lathe; positioning a hybrid tool inside an internal cavity of the workpiece using one or more pole-tips; providing an amount of the lubricant to the internal cavity; and rotating the workpiece with the lathe while controlling positioning of the hybrid tool inside the internal cavity using the one or more pole-types.
FILED Friday, April 22, 2016
APPL NO 15/568494
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents
B24B 1/005 (20130101) Original (OR) Class
B24B 5/40 (20130101)
B24B 31/006 (20130101)
B24B 31/112 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633493 Scott et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Evan A. Scott (Chicago, Illinois);  Sean D. Allen (Chicago, Illinois)
ABSTRACT Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
FILED Friday, July 21, 2017
APPL NO 15/656905
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/107 (20130101)
A61K 9/1273 (20130101)
A61K 31/352 (20130101)
A61K 31/365 (20130101)
A61K 31/436 (20130101)
A61K 38/465 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101)
A61K 49/0047 (20130101)
A61K 49/0054 (20130101)
A61K 49/0065 (20130101)

Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 3/0807 (20130101)
B01F 3/0861 (20130101)
B01F 5/02 (20130101)
B01F 5/0256 (20130101)
B01F 13/0059 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/14 (20130101) Original (OR) Class
C08J 2371/02 (20130101)
C08J 2381/02 (20130101)
C08J 2381/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2320/32 (20130101)

Enzymes
C12Y 301/03001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633556 Tiwari et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) FLORA COATINGS LLC (, None)
ASSIGNEE(S) FLORA COATINGS LLC (PH, Arizona)
INVENTOR(S) Atul Tiwari (Phoenix, Arizona);  Anupama Chaturvedi (Phoenix, Arizona)
ABSTRACT A liquid silicone-based composition for forming a coating, the composition comprising a silazane, an organometallic compound, an alkoxysilane, and an aprotic solvent, wherein when applied to a substrate the liquid composition cures to form a quasi-ceramic coating under ambient conditions.
FILED Thursday, December 28, 2017
APPL NO 15/857568
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/58 (20130101)
C08G 79/00 (20130101)
C08G 79/10 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/34 (20130101)
C08K 3/36 (20130101)
C08K 5/057 (20130101)
C08K 5/5415 (20130101)
C08K 2003/2227 (20130101)
C08K 2201/011 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 183/14 (20130101)
C09D 183/16 (20130101)
C09D 183/16 (20130101)
C09D 185/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633628 Yeh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Daniel H. Yeh (Tampa, Florida);  Ivy Lea Cormier Drexler (St. Petersburg, Florida);  Melanie Pickett (Tampa, Florida);  David Fulcher (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Daniel H. Yeh (Tampa, Florida);  Ivy Lea Cormier Drexler (St. Petersburg, Florida);  Melanie Pickett (Tampa, Florida);  David Fulcher (Tampa, Florida)
ABSTRACT In one embodiment, an algae cultivation system includes a photobioreactor adapted for immersion in growth media contained within the growth media reactor, the photobioreactor including a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, a porous membrane filter incorporated into one of the panels that enables water, carbon dioxide, and nutrients contained within the growth media to pass into the interior space but prevents contaminants contained within the growth media from passing into the interior space, and a gas control valve incorporated into one of the panels that when open enables photosynthetic gas produced by algae growth within the container to escape but when closed prevents the photosynthetic gas from escaping so as to build pressure within the container that forces water out from the container and dewaters the algae.
FILED Monday, November 14, 2016
APPL NO 15/350582
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/22 (20130101)
C12M 29/04 (20130101)
C12M 29/20 (20130101)
C12M 41/48 (20130101)
C12M 47/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633648 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Anna Kuchina (Seattle, Washington);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers.
FILED Friday, February 10, 2017
APPL NO 15/430108
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1037 (20130101) Original (OR) Class
C12N 15/1065 (20130101)
C12N 15/1065 (20130101)
C12N 15/1068 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2525/191 (20130101)
C12Q 2563/103 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633672 Ozias-Akins et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
Agriculture and Food Research Initiative (AFRI)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Peggy Ozias-Akins (Tifton, Georgia);  Joann A. Conner (Tifton, Georgia)
ABSTRACT Methods and compositions disclosed herein generally relate to genes involved in plant reproduction and methods of using the same.
FILED Tuesday, October 21, 2014
APPL NO 15/031019
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8287 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633676 Gonzalez et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Ramon Gonzalez (Houston, Texas);  James Clomburg (Houston, Texas);  Clementina Dellomonaco (Wilmington, Delaware);  Elliot N. Miller (Houston, Texas)
ABSTRACT The invention relates to recombinant microorganisms that have been engineered to produce various chemicals using genes that have been repurposed to create a reverse beta oxidation pathway. Generally speaking, the beta oxidation cycle is expressed and driven in reverse by modifying various regulation points for as many cycles as needed, and then the CoA thioester intermediates are converted to useful products by the action of termination enzymes.
FILED Monday, August 15, 2016
APPL NO 15/237190
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/001 (20130101)
C12N 9/0006 (20130101)
C12N 9/88 (20130101)
C12N 9/1029 (20130101)
C12N 15/70 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/02 (20130101)
C12P 5/026 (20130101)
C12P 7/04 (20130101)
C12P 7/16 (20130101) Original (OR) Class
C12P 7/40 (20130101)
C12P 7/42 (20130101)
C12P 7/6409 (20130101)

Enzymes
C12Y 101/01035 (20130101)
C12Y 102/0105 (20130101)
C12Y 103/99003 (20130101)
C12Y 203/01 (20130101)
C12Y 402/01017 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633700 Ju et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Zengmin Li (Flushing, New York);  John Robert Edwards (St. Louis, Missouri);  Yasuhiro Itagaki (New York, New York)
ABSTRACT This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose.
FILED Monday, November 26, 2018
APPL NO 16/200564
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/11 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/14 (20130101)
C07H 21/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 1/6872 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6876 (20130101)
C12Q 2525/117 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2535/101 (20130101)
C12Q 2535/101 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/107 (20130101)
C12Q 2563/107 (20130101)
C12Q 2565/501 (20130101)
C12Q 2565/501 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633701 Weitz et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David A. Weitz (Bolton, Massachusetts);  Jeremy Agresti (Richmond, California);  Michael P. Weiner (Guilford, Connecticut);  Adam R. Abate (Daly City, California);  Tony Hung (Peachtree City, Georgia)
ABSTRACT The present invention relates to systems and methods for sequencing nucleic acids, including sequencing nucleic acids in fluidic droplets. In one set of embodiments, the method employs sequencing by hybridization using droplets such as microfluidic droplets. In some embodiments, droplets are formed which include a target nucleic acid, a nucleic acid probe, and at least one identification element, such as a fluorescent particle. The nucleic acid probes that hybridize to the target nucleic acid are determined, in some instances, by determining the at least one identification element. The nucleic acid probes that hybridize to the target nucleic acid may be used to determine the sequence of the target nucleic acid. In certain instances, the microfluidic droplets are provided with reagents that modify the nucleic acid probe. In some cases, a droplet, such as those described above, is deformed such that the components of the droplets individually pass a target area.
FILED Monday, August 07, 2017
APPL NO 15/670885
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 1/6874 (20130101)
C12Q 2537/143 (20130101)
C12Q 2563/149 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633750 Tessonnier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa States University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Jean-Philippe Tessonnier (Ames, Iowa);  John Edward Matthiesen (Ames, Iowa);  Nacu B. Hernandez-Cantu (Ames, Iowa);  Eric W. Cochran (Ames, Iowa)
ABSTRACT Various embodiments disclosed relate to electrocatalytic hydrogenation of muconic acid and polymers formed from the reaction products thereof. In various embodiments, the present invention provides an electrocatalytic method to prepare 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a combination thereof, from muconic acid. The method includes passing current through a catalytic cathode in a reactor including an aqueous acidic solution including muconic acid, a supporting electrolyte, and an anode, so as to generate atomic hydrogen on the cathode surface in an amount effective to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. Also disclosed is the polymerization of 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, or a combination thereof with another compound, such as a diamine or a dialcohol, to form a polymer, such as a polyamide or a polyester.
FILED Tuesday, November 10, 2015
APPL NO 15/524888
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/16 (20130101)
C08G 69/26 (20130101)
C08G 69/28 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634544 Przybyla
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Chirp Microsystems, Inc. (Berkeley, California)
ASSIGNEE(S) CHIRP MICROSYSTEMS (Bereley, California)
INVENTOR(S) Richard J. Przybyla (Berkeley, California)
ABSTRACT An ultrasonic transceiver can detect the presence of nearby moving objects while rejecting signals from stationary targets and from transmitter signal feedthrough. Data corresponding to received ultrasound signals are stored in a digital memory. For each sample in a measurement, a difference is calculated between corresponding samples in the stored data corresponding to received signals for current and previous measurements to estimate a time of flight to a moving object.
FILED Thursday, March 09, 2017
APPL NO 15/454363
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 23/2962 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634604 Grier et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) David G. Grier (New York, New York);  Fook Chiong Cheong (Singapore, Singapore);  Ke Xiao (Elmhurst, New York)
ABSTRACT An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
FILED Monday, July 31, 2017
APPL NO 15/665126
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1429 (20130101)
G01N 15/1434 (20130101)
G01N 15/1459 (20130101)
G01N 15/1475 (20130101) Original (OR) Class
G01N 15/1484 (20130101)
G01N 2015/003 (20130101)
G01N 2015/0065 (20130101)
G01N 2015/1445 (20130101)
G01N 2015/1454 (20130101)
G01N 2015/1493 (20130101)
G01N 2015/1497 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/008 (20130101)
G02B 21/0056 (20130101)
G02B 21/0068 (20130101)

Holographic Processes or Apparatus
G03H 1/0005 (20130101)
G03H 2001/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634653 Dasgupta et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas);  DIONEX CORPORATION (Sunnyvale, California)
ASSIGNEE(S) Dionex Corporation (Sunnyvale, California);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Purnendu K. Dasgupta (Arlington, Texas);  Akinde F. Kadjo (Grand Prairie, Texas);  Kannan Srinivasan (Tracy, California)
ABSTRACT Systems, methods and devices are taught for providing analytical methods for peak-shaped responses separated in time or space, including quantitation of chromatographic peaks based on a width measurement of a peak trace at a selected height as a quantitation element. Methods of treating a peak trace as a composition of exponential functions representing a leading and a trailing end are included. Methods that facilitate the detection of impurities in peak trace outputs are also included.
FILED Tuesday, November 28, 2017
APPL NO 15/824962
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Separation
B01D 15/161 (20130101)
B01D 15/163 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/02 (20130101)
G01N 30/16 (20130101)
G01N 30/30 (20130101)
G01N 30/86 (20130101)
G01N 30/8637 (20130101) Original (OR) Class
G01N 2030/025 (20130101)
G01N 2030/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634820 Shih et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Non-Profit Organization (NPO)
Gulf of Mexico Research Initiative (GoMRI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas)
INVENTOR(S) Wei-Chuan Shih (Houston, Texas);  Yu-Lung Sung (Houston, Texas)
ABSTRACT A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.
FILED Friday, May 11, 2018
APPL NO 15/977019
ART UNIT 2872 — Optics
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101)
B29D 11/00365 (20130101)
B29D 11/00442 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/00 (20130101)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101) Original (OR) Class
G02B 1/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634899 Gopinath et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S) Juliet T. Gopinath (Boulder, Colorado);  Emily A. Gibson (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Richard Weir (Longmont, Colorado);  Diego Restrepo (Littleton, Colorado);  Baris Ozbay (Denver, Colorado)
ABSTRACT The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques.
FILED Thursday, January 22, 2015
APPL NO 15/113303
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/14 (20130101)
G02B 6/06 (20130101)
G02B 21/006 (20130101)
G02B 21/0032 (20130101)
G02B 21/0076 (20130101)
G02B 23/26 (20130101)
G02B 23/243 (20130101) Original (OR) Class
G02B 23/2446 (20130101)
G02B 23/2469 (20130101)
G02B 26/005 (20130101)

Pictorial Communication, e.g Television
H04N 5/2256 (20130101)
H04N 2005/2255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636654 Xia
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Fengnian Xia (Orange, Connecticut)
ABSTRACT A scalable approach for the synthesis of black phosphorus (BP) material thin films over large areas is described. A red phosphorus (RP) material thin film may be deposited on a substrate followed by conversion to a BP material thin film using high-pressure alone or high pressure and high temperature. A thin-film of dielectric material such as hexagonal boron nitride (hBN) can be formed on a RP material film before the conversion is performed to improve the crystalline quality and stability of the converted BP material. Surprisingly, an atomically sharp and defect-free interface can be formed between the converted BP material and hBN. The BP material has high crystalline uniformity and can be used to fabricate thin-film transistors and optoelectronic devices such as infrared photodetectors.
FILED Friday, April 06, 2018
APPL NO 15/947202
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 25/006 (20130101)
C01B 25/023 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02422 (20130101)
H01L 21/02521 (20130101)
H01L 21/02631 (20130101) Original (OR) Class
H01L 21/6835 (20130101)
H01L 23/3157 (20130101)
H01L 29/26 (20130101)
H01L 29/786 (20130101)
H01L 29/78696 (20130101)
H01L 2221/68304 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636731 Bakir et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Muhannad S. Bakir (Atlanta, Georgia);  Paul Kim Jo (Atlanta, Georgia)
ABSTRACT Disclosed are various embodiments that involve mechanically flexible interconnects, methods of making mechanically flexible interconnects, methods of using mechanically flexible interconnects, and the like.
FILED Thursday, July 14, 2016
APPL NO 15/744302
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/71 (20130101)
H01L 21/4853 (20130101)
H01L 23/49811 (20130101) Original (OR) Class
H01L 24/16 (20130101)
H01L 2924/01029 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636974 Campos et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  BROOKHAVEN SCIENCE ASSOCIATES, LLC. (Upton, New York)
INVENTOR(S) Luis Miguel Campos (Brooklyn, New York);  Matthew Y. Sfeir (Bethpage, New York);  Jianlong Xia (New York, New York);  Erik Michael Allan Busby (Patchogue, New York);  Jonathan Zhaozhi Low (New York, New York)
ABSTRACT Embodiments of the present invention provides compounds, compositions, and methods for their preparation that provide efficient intramolecular fission, such that local order and strong nearest neighbor coupling is no longer a design constraint. Inventive materials include organic oligomers and polymers designed to exhibit strong intrachain donor-acceptor interactions and provide intramolecular singlet fission, whereby triplet populations can be generated in very high yields of, e.g., 170% or more. The inventive disclosure is directed to polymers of the general formula: [SA-SD]n with a strong electron acceptor (SA), a strong electron donor (SD), and n a positive integer equal to or greater than two; methods for their preparation and monomers used therein, blends, mixtures and formulations containing them; the use of the polymers, blends, mixtures and formulations as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations.
FILED Monday, October 24, 2016
APPL NO 15/333043
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101)
C08G 2261/18 (20130101)
C08G 2261/91 (20130101)
C08G 2261/124 (20130101)
C08G 2261/228 (20130101)
C08G 2261/334 (20130101)
C08G 2261/344 (20130101)
C08G 2261/414 (20130101)
C08G 2261/514 (20130101)
C08G 2261/1412 (20130101)
C08G 2261/1424 (20130101)
C08G 2261/3223 (20130101)
C08G 2261/3243 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0036 (20130101) Original (OR) Class
H01L 51/42 (20130101)
H01L 51/0043 (20130101)
H01L 51/0558 (20130101)
H01L 51/4253 (20130101)
H01L 51/5012 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637293 Costinett et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Daniel Jes Costinett (Knoxville, Tennessee);  Chongwen Zhao (Knoxville, Tennessee)
ABSTRACT A transmitter for wireless power transfer is provided. The transmitter includes an input port, a first transmission port, a second transmission port, an inverter, and a controller. An input of the inverter is coupled to the input port, and an output of the inverter is coupled in parallel to the first and second transmission ports. The controller is programmed to control the inverter to modulate an output voltage at the output of the inverter such that power from the input port is transmitted at a first frequency through the first transmission port and at a second frequency through the second transmission port.
FILED Thursday, September 28, 2017
APPL NO 15/718767
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/12 (20160201) Original (OR) Class
H02J 50/40 (20160201)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/33561 (20130101)
H02M 7/53871 (20130101)
H02M 2007/4815 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/1441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637391 Forrest et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Kyusang Lee (Ann Arbor, Michigan);  Matthew Shlian (Ann Arbor, Michigan);  Chih-Wei Chien (Ann Arbor, Michigan);  Peicheng Ku (Ann Arbor, Michigan);  Aaron Lamoreux (Ann Arbor, Michigan);  Max Shtein (Ann Arbor, Michigan)
ABSTRACT There is disclosed Kirigami-inspired structures for use in solar tracking applications. When coupled with thin-film active materials, the disclosed microstructures can track solar position and maximize solar power generation. In one embodiment, there is disclosed a photovoltaic system comprising a single-axis, or multi-axis solar tracking structure comprising a support structure made of a flexible material having a defined unit cell structure, and a flexible photovoltaic cell disposed on the support structure. There is also disclosed methods of making such structures in which the photovoltaic cell is mounted to the support structure by a direct-attachment bonding processes such as cold-welding.
FILED Friday, November 28, 2014
APPL NO 15/034299
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/054 (20141201)
H01L 31/1844 (20130101)
H01L 31/03046 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/32 (20141201) Original (OR) Class
H02S 30/20 (20141201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637575 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Xinyu Zhang (Madison, Wisconsin);  Chi Zhang (Madison, Wisconsin)
ABSTRACT A system for identifying the location of the mobile device uses standard fluorescent light fixtures commonly found in indoor environments and detects minor variations in the light output of those fixtures caused by normal manufacturing variation. These variations are catalogued as identifying fingerprints together with location of the light fixtures to provide for navigation.
FILED Wednesday, May 25, 2016
APPL NO 15/164195
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/116 (20130101) Original (OR) Class
H04B 10/1141 (20130101)

Wireless Communication Networks
H04W 4/02 (20130101)
H04W 4/024 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637586 Zheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Yahong Rosa Zheng (Rolla, Missouri);  Weimin Duan (San Diego, California);  Chengshan Xiao (Rolla, Missouri)
ASSIGNEE(S) National Science Foundation (Alexandria, Virginia)
INVENTOR(S) Yahong Rosa Zheng (Rolla, Missouri);  Weimin Duan (San Diego, California);  Chengshan Xiao (Rolla, Missouri)
ABSTRACT Systems and methods for underwater communication using a MIMO acoustic channel. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder.
FILED Friday, August 25, 2017
APPL NO 15/686390
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Transmission
H04B 11/00 (20130101)
H04B 13/02 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/03057 (20130101)
H04L 27/0008 (20130101)
H04L 2025/03426 (20130101)
H04L 2025/03636 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10632828 Trase et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Larry M. Trase (Litchfield, Ohio);  Ralph H. Jansen (Westlake, Ohio);  Peter E. Kascak (Cleveland, Ohio)
ABSTRACT A prime mover is combined with a flywheel storage device and a control system to implement a flywheel pulse and glide system in a vehicle. In one embodiment, the control system is configured to cycle power delivery between the prime mover and the flywheel storage device to power the vehicle. The prime mover, when activated by the control system, is configured to power the vehicle and spin up the flywheel storage device to capture a sufficient amount of energy.
FILED Friday, March 29, 2013
APPL NO 13/853308
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/10 (20130101) Original (OR) Class
B60K 6/30 (20130101)
B60K 6/48 (20130101)
B60K 6/105 (20130101)
B60K 6/442 (20130101)
B60K 6/485 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 2240/44 (20130101)

Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/06 (20130101)
B60W 30/18127 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633256 Guo et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Haiquan Guo (Avon, Ohio);  Frances I. Hurwitz (Shaker Heights, Ohio)
ABSTRACT Aerogels, aerogel composites and methods of making the same are discussed. One example method can include the act of creating a Boehmite colloid and adding a hydrolyzed silicon precursor to form a sol. A reinforcement can be infused with the sol, gelled to form a gel, then dried to form an aerogel composite. Such a method can also include the acts of performing one or more solvent exchanges and subjecting the gel composite to subcritical drying. Additionally, such a method can include the act of heat treating the aerogel composite. The aerogel composite can be used in high temperature, flexible seals capable of withstanding temperatures, pressures, and compression levels associated with aerodynamic heating generated during flight and in aerospace applications. The aerogel composite also can be used in thermal protection systems designed for fire protection for structures or in personnel fire protective equipment.
FILED Wednesday, April 19, 2017
APPL NO 15/491168
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 33/157 (20130101) Original (OR) Class

Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 59/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10634820 Shih et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Non-Profit Organization (NPO)
Gulf of Mexico Research Initiative (GoMRI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas)
INVENTOR(S) Wei-Chuan Shih (Houston, Texas);  Yu-Lung Sung (Houston, Texas)
ABSTRACT A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.
FILED Friday, May 11, 2018
APPL NO 15/977019
ART UNIT 2872 — Optics
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101)
B29D 11/00365 (20130101)
B29D 11/00442 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/00 (20130101)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101) Original (OR) Class
G02B 1/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635761 English et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) ENERGID TECHNOLOGIES CORPORATION (Cambridge, Massachusetts)
ASSIGNEE(S) Energid Technologies Corporation (Cambridge, Massachusetts)
INVENTOR(S) James D. English (Alva, Florida);  Ryan S. Penning (Madison, Wisconsin);  Douglas E. Barker (Somerville, Massachusetts);  James A. Bacon (Bourbonnais, Illinois)
ABSTRACT A method, computer program product, and computer system for configuring a stochastic simulation scenario, wherein the stochastic simulation scenario may include one or more variables without a complete probability distribution. The stochastic simulation scenario may be executed to generate one or more results of the stochastic simulation scenario. At least a portion of the one or more variables without the probability distribution may be optimized using one or more optimization metrics on the one or more results of the stochastic simulation scenario.
FILED Friday, April 29, 2016
APPL NO 15/142157
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/23446 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 2201/0213 (20130101)

Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
G06F 17/5095 (20130101)
G06F 2217/10 (20130101)
G06F 2217/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10636323 Buras et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) TIETRONIX SOFTWARE, INC. (Houston, Texas)
ASSIGNEE(S) Tienovix, LLC (Houston, Texas)
INVENTOR(S) William R. Buras (Friendswood, Texas);  Craig S. Russell (League City, Texas);  Kyle Q. Nguyen (League City, Texas)
ABSTRACT A medical guidance system providing real-time, three-dimensional (3D) augmented reality (AR) feedback guidance to a novice user of medical equipment having limited medical training, to achieve improved diagnostic or treatment outcomes.
FILED Tuesday, January 23, 2018
APPL NO 15/878314
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/52 (20130101)
A61B 8/085 (20130101)
A61B 8/466 (20130101)
A61B 8/467 (20130101)
A61B 8/4245 (20130101)
A61B 8/4254 (20130101)
A61B 8/4263 (20130101)
A61B 34/20 (20160201)
A61B 90/361 (20160201)
A61B 2034/2048 (20160201)
A61B 2034/2055 (20160201)
A61B 2090/365 (20160201)
A61B 2090/378 (20160201)
A61B 2090/3945 (20160201)
A61B 2562/0219 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/017 (20130101)

Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/016 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/065 (20130101)
G09B 23/286 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
G16H 40/63 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10637202 Mitchell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Goodrich Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Goodrich Corporation (Charlotte, North Carolina)
INVENTOR(S) Michael D. Mitchell (Albuquerque, New Mexico)
ABSTRACT A tool for demating multi-pin connectors includes a first fork including an inner fork member and an outer fork member operatively connected for relative movement parallel to a longitudinal fork axis. A second fork is spaced apart from the first fork wherein the second fork includes an inner fork member and an outer fork member operatively connected for relative movement parallel to the longitudinal fork axis. A handle connects the first fork to the second fork. The handle includes an outer handle member fixedly connecting the outer fork members of the first and second forks, and the handle includes an inner handle member fixedly connecting the inner fork members of the first and second forks. Relative movement of the inner and outer handle members causes relative movement of the inner and outer fork members of the first and second forks for demating multi-pin electrical connectors from sockets.
FILED Thursday, April 27, 2017
APPL NO 15/499182
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding
B25B 27/00 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 43/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10633671 Fellers et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) John Fellers (Manhattan, Kansas);  Harold N. Trick (Olsburg, Kansas);  Luisa Cruz (Plant City, Florida);  Jessica Rupp (Manhattan, Kansas)
ABSTRACT Disclosed is a dsRNA construct used to silencing specific eukaryotic translation initiation factor in plants to produce a plant resistant to viruses such as Potyviruses, Luteoviruses, and Furoviruses. More specifically, the plant would be resistant to viruses such as Wheat streak mosaic virus, Triticum mosaic virus, Soil bourne mosaic virus, or Barley yellow dwarf virus. Also disclosed are non-transgenic wheat plants having the genes for eIF(iso)4E-2 or eIF4G silenced.
FILED Friday, January 19, 2018
APPL NO 15/875168
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8218 (20130101)
C12N 15/8283 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10633672 Ozias-Akins et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
Agriculture and Food Research Initiative (AFRI)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Peggy Ozias-Akins (Tifton, Georgia);  Joann A. Conner (Tifton, Georgia)
ABSTRACT Methods and compositions disclosed herein generally relate to genes involved in plant reproduction and methods of using the same.
FILED Tuesday, October 21, 2014
APPL NO 15/031019
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8287 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 10633248 Ashikhmin
FUNDED BY
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Alcatel Lucent (Boulogne-Billancourt, France)
ASSIGNEE(S) ALCATEL LUCENT (Nozay, France)
INVENTOR(S) Alexei Ashikhmin (Morristown, New Jersey)
ABSTRACT An apparatus includes a device having n input ports and n output ports. The n input ports are configured to receive n corresponding physical objects of a physically processed, quantum redundancy coded state. The n output ports are configured to output the n physical objects in the physically processed, quantum redundancy coded state. The device is configured to measure bits of a syndrome of the physically processed, quantum redundancy coded state by passing the n physical objects through the device. The device is configured to measure a parity check bit for the measured bits of the syndrome by the passing the n physical objects through the device.
FILED Monday, March 05, 2018
APPL NO 15/911909
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Coding; Decoding; Code Conversion in General
H03M 13/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10635971 Chelian et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Inbound, Controlled, Air-Releasable, Unrecoverable Systems (ICARUS)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Suhas E. Chelian (San Jose, California);  Matthias Ziegler (Agoura Hills, California);  James Benvenuto (Beverly Hills, California);  Jeffrey Lawrence Krichmar (Cardiff By the Sea, California);  Randall C. O'Reilly (Boulder, Colorado);  Rajan Bhattacharyya (Sherman Oaks, California)
ABSTRACT Described is a system for proactive and reactive cognitive control using a neural module. The system calculates, for each hypothesis of a set of hypotheses, a probability that an event will occur. The neural module comprises a plurality of neurons and includes the PC module, a prefrontal cortex (PFC) module, an anterior cingulate cortex (ACC) module, a locus coeruleus (LC) module, and a basal forebrain (BF) module. The set of hypotheses are related to tasks to be performed by a plurality of groups, each group having a corresponding hypothesis. For each probability, the system calculates a conflict value across all hypotheses with the ACC module, compares each conflict value to a predetermined threshold using the BF and LC modules. A determination is made whether to directly output the calculated probability or perform an additional probability calculation and output an updated probability.
FILED Tuesday, December 01, 2015
APPL NO 14/955722
ART UNIT 2121 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
G06N 7/005 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 10634584 Farris et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) The Mitre Corporation (McLean, Virginia)
ASSIGNEE(S) ROKU, INC. (Los Gatos, California)
INVENTOR(S) Michael Heath Farris (Vienna, Virginia);  Kevin Robert Gemp (Falls Church, Virginia);  David Masters (Great Falls, Virginia)
ABSTRACT A microscopic collection device, method for collecting a microscopic sample from a target surface, and the work stand for holding the microscopic collection device are provided. The microscopic collection device includes a holding element comprising a handle at one end and a collection platform connected to the holding element at a second end. The collection platform includes a collection surface on which the microscopic sample is deposited when the microscopic collection device comes into contact with the target surface. A tape is inserted through a slit and wrapped around the collection platform. The work stand includes a slit capable of holding the microscopic collection device such that the collection platform is perpendicular to the top surface of the work stand. A microscopic sample, collected using the microscopic collection device, is not only collected from the target surface but is also concentrated onto the collection face of the tape. Removal of the collection face of the tape excludes excess tape that would disrupt downstream analysis of the microscopic sample.
FILED Thursday, December 17, 2015
APPL NO 14/973083
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/02 (20130101) Original (OR) Class
G01N 1/2813 (20130101)
G01N 2001/028 (20130101)
G01N 2001/2833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10633114 Momoh
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) James Momoh (Upper Marlboro, Maryland)
ASSIGNEE(S) HOWARD UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) James Momoh (Upper Marlboro, Maryland)
ABSTRACT An airport lighting system includes one or more lighting elements, a transient protection apparatus, and one or more electrical control cabinets. The transient protection apparatus is coupled to the one or more lighting elements. One or more electrical control cabinets are coupled to the transient protection apparatus. Each of the control cabinets produces one or more of control and power signals that are effective to operate the one or more lighting elements. The transient protection apparatus is configured to provide protection for one or more of the electrical control cabinets and the one or more lighting elements from electrical surges.
FILED Tuesday, December 06, 2016
APPL NO 16/060249
ART UNIT 2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 1/20 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems
F21W 2111/06 (20130101)

Traffic Control Systems
G08G 5/025 (20130101)
G08G 5/0026 (20130101)

Emergency Protective Circuit Arrangements
H02H 9/005 (20130101)
H02H 9/041 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 37/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 10634820 Shih et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Non-Profit Organization (NPO)
Gulf of Mexico Research Initiative (GoMRI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas)
INVENTOR(S) Wei-Chuan Shih (Houston, Texas);  Yu-Lung Sung (Houston, Texas)
ABSTRACT A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.
FILED Friday, May 11, 2018
APPL NO 15/977019
ART UNIT 2872 — Optics
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101)
B29D 11/00365 (20130101)
B29D 11/00442 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/00 (20130101)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101) Original (OR) Class
G02B 1/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10633425 Antipov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) SILVER CREEK PHARMACEUTICALS, INC. (San Francisco, California)
ASSIGNEE(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
INVENTOR(S) Laura D. J. Antipov (Oakland, California);  Shawdee Eshghi (Oakland, California);  Kristopher M. Kuchenbecker (Los Angeles, California);  Bjorn L. Millard (Orinda, California);  Matthew D. Onsum (El Cerrito, California);  Andrea D. Nickerson (San Francisco, California);  Timothy R. Stowe (San Francisco, California);  Yan Zhang (San Francisco, California)
ABSTRACT Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue.
FILED Tuesday, July 03, 2018
APPL NO 16/026319
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/65 (20130101) Original (OR) Class
C07K 14/765 (20130101)
C07K 2319/33 (20130101)
C07K 2319/035 (20130101)
C07K 2319/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 28, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200428.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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