FedInvent™ Patents
Patent Details for Tuesday, April 28, 2020
This page was updated on Monday, March 27, 2023 at 06:04 AM GMT
Department of Health and Human Services (HHS)
US 10631730 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | David Huang (Portland, Oregon); Yali Jia (Portland, Oregon); Miao Zhang (Portland, Oregon) |
ABSTRACT | Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset. |
FILED | Monday, February 04, 2019 |
APPL NO | 16/266545 |
ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) A61B 3/1241 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 2207/10101 (20130101) G06T 2207/20182 (20130101) G06T 2207/30041 (20130101) G06T 2207/30104 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631775 | Thelen et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Darryl Gerard Thelen (Madison, Wisconsin); Jack Anthony Martin (Madison, Wisconsin); Matt S. Allen (Middleton, Wisconsin); Daniel Joseph Segalman (East Lansing, Michigan); Laura Ann Slane (Penfield, New York) |
ABSTRACT | Axial stress or similar properties in a stressed tendon or ligament are measured by mechanical excitation of a shear wave in the tendon or ligament measured using ultrasonic displacement techniques at least two different longitudinal positions to derive a shear wave propagation speed. This shear wave propagation speed may be equated to an axial stress on the tissue using a model. Rapidly repeated measurements allow dynamic axial stress measurements to be obtained for clinical study. |
FILED | Friday, August 28, 2015 |
APPL NO | 14/839448 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) A61B 5/4519 (20130101) Original (OR) Class A61B 5/4523 (20130101) A61B 5/4533 (20130101) A61B 8/485 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) A61B 2562/0219 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631792 | Pinsky |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HGIHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Michael R. Pinsky (Pittsburgh, Pennsylvania) |
ABSTRACT | A system and method for determining a patient's susceptibility to develop cardiorespiratory instability wherein physiological parameters are analyzed with respect to a dynamics systems model to produce and indicator associated with a probability that the patient will become unstable is provided. |
FILED | Friday, December 20, 2013 |
APPL NO | 14/137576 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0022 (20130101) A61B 5/029 (20130101) A61B 5/742 (20130101) A61B 5/02028 (20130101) A61B 5/02055 (20130101) A61B 5/02108 (20130101) A61B 5/02405 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 5/7475 (20130101) A61B 5/14539 (20130101) A61B 5/14551 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/70 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631800 | Siewerdsen et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Carestream Health, Inc. (Rochester, New York) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Carestream Health, Inc. (Rochester, New York) |
INVENTOR(S) | Jeffrey H. Siewerdsen (Baltimore, Maryland); J. Webster Stayman (Baltimore, Maryland); Wojciech Zbijewski (Baltimore, Maryland); John Yorkston (Rochester, New York) |
ABSTRACT | The present invention is directed to a system and method for dual-energy (DE) or multiple-energy (spectral) cone-beam computed tomography (CBCT) using a configuration of multiple x-ray sources and a single detector. The x-ray sources are operated to produce x-ray spectra of different energies (peak kilovoltage (kVp) and/or filtration). Volumetric 3D image reconstruction and dual or triple energy 3D image decomposition can be executed using data from the CBCT scan. The invention allows for a variety of selections in energy and filtration associated with each source and the order of pulsing for each source (“firing pattern”). The motivation for distributing the sources along the z direction in CBCT includes extension of the longitudinal field of view and reduction of cone-beam artifacts. |
FILED | Tuesday, November 25, 2014 |
APPL NO | 15/030818 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/482 (20130101) A61B 6/505 (20130101) A61B 6/4007 (20130101) Original (OR) Class A61B 6/4035 (20130101) A61B 6/4085 (20130101) A61B 6/5205 (20130101) A61B 6/5235 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631877 | Murphy et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia); The United States of AMerica, as represented by the Secretary of the Defense (Washington, District of Columbia) |
INVENTOR(S) | Ryan Murphy (Columbia, Maryland); Ehsan Basafa (Baltimore, Maryland); Mehran Armand (Fulton, Maryland); Chad Gordon (Lutherville, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland) |
ABSTRACT | Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating. |
FILED | Wednesday, November 26, 2014 |
APPL NO | 15/100241 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631936 | Krishnaswamy et al. |
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APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Richard J. Barth, Jr. (Hanover, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire) |
ABSTRACT | A method for guiding resection of local tissue from a patient includes generating at least one image of the patient, automatically determining a plurality of surgical guidance cues indicating three-dimensional spatial properties associated with the local tissue, and generating a visualization of the surgical guidance cues relative to the surface. A system for generating surgical guidance cues for resection of a local tissue from a patient includes a location module for processing at least one image of the patient to determine three-dimensional spatial properties of the local tissue, and a surgical cue generator for generating the surgical guidance cues based upon the three-dimensional spatial properties. A patient-specific locator form for guiding resection of local tissue from a patient includes a locator form surface matching surface of the patient, and a plurality of features indicating a plurality of surgical guidance cues, respectively. |
FILED | Friday, June 10, 2016 |
APPL NO | 15/735907 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/20 (20160201) Original (OR) Class A61B 2017/008 (20130101) A61B 2017/3405 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10631973 | Linderman et al. |
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APPLICANT(S) | Stephen Linderman (St. Louis, Missouri); Guy Genin (St. Louis, Missouri); Stavros Thomopoulos (Clayton, Missouri); Kollbe Ahn (Santa Barbara, California); Victor Mark Birman (Chesterfield, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Stephen Linderman (St. Louis, Missouri); Guy Genin (St. Louis, Missouri); Stavros Thomopoulos (Clayton, Missouri); Kollbe Ahn (Santa Barbara, California); Victor Mark Birman (Chesterfield, Missouri) |
ABSTRACT | Provided herein are compositions and methods for treating a subject with damaged tissue, such as an injury associated with a tissue to tissue (e.g., a connective tissue-to-connective tissue or tissue to bone) interface. One aspect provides an adhesive film or adhesive layer, optionally comprising a biomaterial, tissue growth factors, including CTGF/CCN2, or cells. |
FILED | Friday, March 10, 2017 |
APPL NO | 15/455792 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1146 (20130101) A61B 17/06166 (20130101) A61B 2017/00884 (20130101) A61B 2017/00951 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class A61F 2/28 (20130101) A61F 2220/005 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/145 (20130101) A61L 24/0005 (20130101) A61L 24/0015 (20130101) A61L 24/0031 (20130101) A61L 2300/64 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) A61L 2430/24 (20130101) A61L 2430/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632013 | Prausnitz et al. |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); EMORY UNIVERSITY (Atlanta, Georgia) |
INVENTOR(S) | Mark R. Prausnitz (Atlanta, Georgia); Henry F. Edelhauser (Atlanta, Georgia); Samirkumar Rajnikant Patel (Atlanta, Georgia) |
ABSTRACT | Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye. |
FILED | Tuesday, September 19, 2017 |
APPL NO | 15/708779 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/0023 (20130101) A61M 2210/0612 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632070 | Zhang et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming Jack Hu (San Diego, California); Weiwei Gao (La Jolla, California); Jonathan Coop (La Jolla, California) |
ABSTRACT | The present invention provides for compositions comprising a polymeric hydrogel impregnated with a toxin-absorbing or binding nanoparticle. The present invention also provides for the use of the above compositions for decreasing or neutralizing the effect of a toxin, or for treating or preventing an infection by a microbe that produces a toxin, in a subject. The exemplary toxin is a biological toxin such as a viral, bacterial, fungal, plant or animal toxin. |
FILED | Monday, September 24, 2018 |
APPL NO | 16/139612 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/0019 (20130101) A61K 9/1629 (20130101) A61K 9/5068 (20130101) A61K 9/5115 (20130101) A61K 9/5153 (20130101) A61K 9/5176 (20130101) A61K 31/49 (20130101) A61K 31/49 (20130101) A61K 35/17 (20130101) A61K 35/18 (20130101) A61K 35/19 (20130101) A61K 35/58 (20130101) A61K 35/63 (20150115) A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/404 (20130101) A61L 2400/12 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632072 | Costa et al. |
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APPLICANT(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
INVENTOR(S) | Antonio Costa (Farmington, Connecticut); Diane J. Burgess (Farmington, Connecticut) |
ABSTRACT | The present disclosure provides systems and methods for the continuous production of liposomes. An example method includes (a) mixing a solution of lipid and organic solvent from one or more containers to create an organic solvent-lipid solution, (b) providing the organic solvent-lipid solution to a first inlet of an injection port at a first flow rate, wherein the first inlet is in fluid communication with a first conduit, (c) providing an aqueous solution to a second inlet of the injection port at a second flow rate, wherein the second inlet is influid communication with a second conduit, wherein the first conduit is positioned concentrically within the second conduit at an outlet of the injection port, and wherein the first conduit extends through the outlet of the injection port, and (d) mixing the organic lipid solution and the aqueous solution to create a plurality of liposomes. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/557575 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1277 (20130101) Original (OR) Class Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/045 (20130101) B01F 15/00149 (20130101) B01F 2215/0032 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632080 | Zhang et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Clark Zhang (Sunnyvale, California); Panagiotis Mastorakos (Charlottesville, Virginia); Jung Soo Suk (Baltimore, Maryland); Justin Hanes (Baltimore, Maryland) |
ABSTRACT | Improved distribution can be achieved by delivering nanoparticles possessing non-adhesive surfaces via CED in a hyperosmolar infusate solution. This delivery strategy minimizes the hindrances imposed by the brain extracellular matrix and reduces the concentration of therapeutic that is confined within perivascular spaces. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/759465 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 9/5138 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 49/0032 (20130101) A61K 49/0093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632088 | Silverman et al. |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Hoang V. Le (Oxford, Mississippi); Rima L. McLeod (Chicago, Illinois); Dustin D. Hawker (Evanston, Illinois) |
ABSTRACT | Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human γ-aminobutyric aminotransferase (GABA-AT). |
FILED | Tuesday, October 10, 2017 |
APPL NO | 15/728714 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/03 (20130101) A61K 31/13 (20130101) A61K 31/035 (20130101) A61K 31/40 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/341 (20130101) A61K 31/381 (20130101) Acyclic or Carbocyclic Compounds C07C 229/34 (20130101) C07C 229/38 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1096 (20130101) Enzymes C12Y 206/01013 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632091 | Snodgrass et al. |
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FUNDED BY |
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APPLICANT(S) | VISTAGEN THERAPEUTICS, INC. (South San Francisco, California) |
ASSIGNEE(S) | VISTAGEN THERAPEUTICS, INC. (South San Francisco, California) |
INVENTOR(S) | H. Ralph Snodgrass (South San Francisco, California); Allen E. Cato (Durham, North Carolina); Jack S. Hicklin (San Diego, California) |
ABSTRACT | Compositions of L-4-chlorokynurenine are provided, as are methods for the treatment of neurologica dyslinction. |
FILED | Monday, May 14, 2018 |
APPL NO | 15/978855 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632099 | Croatt et al. |
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APPLICANT(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina); Cedric Pearce (Chapel Hill, North Carolina) |
ASSIGNEE(S) | University of North Carolina at Greensboro (Greensboro, North Carolina) |
INVENTOR(S) | Mitchell P. Croatt (Greensboro, North Carolina); Lara Fakhouri (Greensboro, North Carolina); Nicholas H. Oberlies (Greensboro, North Carolina); Cedric Pearce (Chapel Hill, North Carolina) |
ABSTRACT | This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones. |
FILED | Friday, August 30, 2019 |
APPL NO | 16/556626 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/336 (20130101) A61K 31/365 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Heterocyclic Compounds C07D 313/00 (20130101) C07D 493/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632121 | Mellinghoff et al. |
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APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Ingo Kai Mellinghoff (New York, New York); Sara Kubek (Seattle, Washington) |
ABSTRACT | In certain embodiments the present invention involves methods of killing tumor cells that comprise an oncogenic PDGFR mutation, and methods of treating subjects having tumors that comprise such tumor cells. In some embodiments such methods involve using PI3K inhibitors, or a combination of a PI3K inhibitor and an mTOR inhibitor, or a dual PI3K/mTOR inhibitor. The present invention also provides methods for determining whether a subject is a candidate for treatment, methods for evaluating the efficacy of treatment, and other methods, compositions, model systems, and assays. |
FILED | Friday, May 15, 2015 |
APPL NO | 15/311582 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/498 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/5377 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632122 | Hol et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Wilhelmus G. J. Hol (Seattle, Washington); Eric T. Larson (Seattle, Washington); Dustin James Maly (Seattle, Washington); Wesley C. Van Voorhis (Seattle, Washington); Ethan Merritt (Seattle, Washington); Kayode K. Ojo (Seattle, Washington) |
ABSTRACT | The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein. |
FILED | Thursday, May 02, 2019 |
APPL NO | 16/402227 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/4985 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) Y02A 50/488 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632140 | Pavel et al. |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Ana Brandusa Pavel (New York, New York); Joshua David Campbell (Sharon, Massachusetts); Marc Elliott Lenburg (Brookline, Massachusetts); Avrum Elliot Spira (Newton, Massachusetts) |
ABSTRACT | The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs. |
FILED | Tuesday, April 23, 2019 |
APPL NO | 16/391473 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6886 (20130101) C12Q 2539/10 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632152 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Chia-Yung Wu (San Francisco, California); James Onuffer (Alameda, California); Wendell A. Lim (San Francisco, California) |
ABSTRACT | The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided. |
FILED | Friday, August 04, 2017 |
APPL NO | 15/669707 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 47/6891 (20170801) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70575 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2803 (20130101) C07K 16/2866 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/14 (20130101) C12N 9/90 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 502/01008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632153 | Spees |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (Burlington, Vermont) |
ASSIGNEE(S) | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (Burlington, Vermont) |
INVENTOR(S) | Jeffrey Spees (Colchester, Vermont) |
ABSTRACT | The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such compositions. |
FILED | Monday, January 29, 2018 |
APPL NO | 15/882767 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Original (OR) Class A61K 38/30 (20130101) A61K 38/195 (20130101) A61K 38/1833 (20130101) A61K 38/1866 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0657 (20130101) C12N 2501/10 (20130101) C12N 2501/12 (20130101) C12N 2501/105 (20130101) C12N 2501/165 (20130101) C12N 2502/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632155 | Tseng et al. |
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FUNDED BY |
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APPLICANT(S) | TissueTech, Inc. (Miami, Florida) |
ASSIGNEE(S) | TISSUETECH, INC. (Miami, Florida) |
INVENTOR(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Shenzhen, China PRC) |
ABSTRACT | Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases. |
FILED | Wednesday, January 24, 2018 |
APPL NO | 15/879042 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/982 (20130101) A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 9/19 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/738 (20130101) A61K 35/48 (20130101) A61K 35/50 (20130101) Original (OR) Class A61K 38/39 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 38/4886 (20130101) A61K 38/4886 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2800/74 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/40 (20130101) A61L 15/44 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Peptides C07K 14/78 (20130101) C07K 14/4702 (20130101) C07K 14/4718 (20130101) C07K 14/8114 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632170 | Lambris et al. |
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FUNDED BY |
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APPLICANT(S) | John D. Lambris (Bryn Mawr, Pennsylvania); Maciej M. Markiewski (Collegeville, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | John D. Lambris (Bryn Mawr, Pennsylvania); Maciej M. Markiewski (Collegeville, Pennsylvania) |
ABSTRACT | Methods for treating, preventing or delaying onset of tumor formation and other forms of cancer are disclosed. The methods involve administration of a complement inhibitor to inhibit C5a receptor signaling in the tumor microenvironment. |
FILED | Thursday, February 19, 2009 |
APPL NO | 12/918101 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632175 | Goodyear et al. |
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FUNDED BY |
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APPLICANT(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Laurie J. Goodyear (Southborough, Massachusetts); Kristin I. Stanford (Roslindale, Massachusetts) |
ABSTRACT | The present invention is related to methods and compositions effective in regulating glycemic control in subject individuals in need of the regulation of glycemic control. Said individuals may have diabetes or be prediabetic condition receive therapeutically effective amounts of identified secreted proteins in an amount suitable for modulating glycemic control and to thereby treat or prevent diabetes in said subject. |
FILED | Tuesday, March 04, 2014 |
APPL NO | 14/771677 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1841 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632178 | Whitsett et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Jeffrey A. Whitsett (Cincinnati, Ohio); Machiko Ikegami (Cincinnati, Ohio) |
ABSTRACT | Surfactant protein D (SP-D) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (BPD). |
FILED | Wednesday, November 14, 2018 |
APPL NO | 16/190456 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/395 (20130101) Original (OR) Class A61K 38/395 (20130101) A61K 38/1732 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632180 | Dubal |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Dena Dubal (Oakland, California) |
ABSTRACT | Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides. |
FILED | Friday, February 05, 2016 |
APPL NO | 15/548306 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/47 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Enzymes C12Y 302/01031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632184 | Livengood et al. |
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FUNDED BY |
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APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Jill Ann Livengood (Fort Collins, Colorado); Timothy Duane Powell (Maynard, Massachusetts) |
ABSTRACT | Embodiments herein relate to compositions and methods for stabilizing live alphaviruses. Other embodiments relate to compositions and methods for reducing degradation of live, attenuated alphaviruses. Certain embodiments relate to providing a stabilizing composition while reducing immune reaction in a subject to excipients that stabilize the live alphaviruses by providing improved formulations. Yet other embodiments relate to uses of compositions disclosed herein in kits for portable applications and methods wherein the compositions reduce degradation of the live alphaviruses. |
FILED | Monday, March 27, 2017 |
APPL NO | 16/088816 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/183 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/36134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632185 | Kinney |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Claire Y. H. Kinney (Fort Collins, Colorado) |
ABSTRACT | Chimeric flaviviruses that include non-coding regions, non-structural proteins, a capsid (C) protein and a portion of a premembrane (prM) signal sequence from West Nile virus (WNV), and a portion of a prM signal sequence, a prM protein and an E protein from Zika virus (VIKV) are described. Also described are compositions and methods for eliciting an immune response in a subject, such as an immune response directed against ZIKV. Diagnostic assays that utilize chimeric West Nile/Zika viruses are further described. |
FILED | Thursday, July 06, 2017 |
APPL NO | 16/315897 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/525 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24141 (20130101) C12N 2770/24144 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) Technologies for Adaptation to Climate Change Y02A 50/392 (20180101) Y02A 50/394 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632188 | Bronshtein |
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FUNDED BY |
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APPLICANT(S) | Universal Stabilization Technologies, Inc. (San Diego, California) |
ASSIGNEE(S) | UNIVERSAL STABILIZATION TECHNOLOGIES, INC. (San Diego, California) |
INVENTOR(S) | Victor Bronshtein (San Diego, California) |
ABSTRACT | The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications. |
FILED | Friday, June 30, 2017 |
APPL NO | 15/638937 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/145 (20130101) A61K 35/744 (20130101) A61K 39/07 (20130101) A61K 39/09 (20130101) A61K 39/12 (20130101) A61K 39/205 (20130101) Original (OR) Class A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/20134 (20130101) C12N 2760/20161 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632190 | Sampson et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | John H. Sampson (Durham, North Carolina); Duane A. Mitchell (Durham, North Carolina) |
ABSTRACT | The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided. |
FILED | Monday, August 14, 2017 |
APPL NO | 15/676330 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632247 | Woods et al. |
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FUNDED BY |
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APPLICANT(S) | CLPH, LLC (Palo Alto, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Christopher E. Woods (Palo Alto, California); Christian S. Eversull (Palo Alto, California); Stephen A. Leeflang (Sunnyvale, California) |
ABSTRACT | Systems and methods are provided for imaging cardiac tissue using fluorescent dyes delivered into tissue. A distal end of an imaging device may be introduced into a chamber of the heart, and fluorescent dye may be delivered into one or more body lumens in the heart such that the dye is absorbed by cardiac tissue adjacent the chamber. Images of the cardiac tissue adjacent the chamber may be acquired using the imaging device, the dye enhancing identifying cardiac electrical activity within the cardiac tissue. Optionally, based on the identified cardiac electrical activity, tissue within the heart may be ablated or otherwise treated. |
FILED | Friday, January 23, 2015 |
APPL NO | 14/604671 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/0215 (20130101) A61B 5/0402 (20130101) A61B 18/24 (20130101) A61B 2018/00386 (20130101) A61B 2018/00577 (20130101) A61B 2018/00648 (20130101) A61B 2018/00839 (20130101) A61B 2018/00982 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/007 (20130101) Original (OR) Class A61M 25/10 (20130101) A61M 2210/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632305 | Bloch et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Maryland, Baltimore (Baltimore, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
INVENTOR(S) | Robert J. Bloch (Baltimore, Maryland); Andrea O'Neill (Towson, Maryland); Joseph A. Roche (Balitmore, Maryland); Paraskevi Sakellariou (Athens, Greece) |
ABSTRACT | Studies of the pathogenic mechanisms underlying human myopathies and muscular dystrophies often require animal models, but models of some human diseases are not yet available. The present invention provides methods to promote the engraftment and development of myogenic cells from individuals with such diseases into mature muscle tissue in mice to treat muscle diseases, muscle injury and reduced muscle function. Immortalized human myogenic precursor cells (hMPCs) form mature human myofibers following implantation into the hindlimbs of immunodeficient mice. The engraftment of the cells and their development into mature muscle myofibers is promoted by intermittent neuromuscular electrical stimulation (iNMES) of the peroneal nerve of the engrafted limb. The human myofibers that form are innervated, their contractile apparatus is fully differentiated, and they are comprised of human myonuclei, with minimal contamination by murine myonuclei. |
FILED | Friday, October 17, 2014 |
APPL NO | 15/029191 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2227/105 (20130101) A01K 2267/035 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) A61F 2002/0894 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/326 (20130101) Original (OR) Class A61N 1/36003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632464 | Schenk zu Schweinsberg et al. |
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FUNDED BY |
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APPLICANT(S) | Alere San Diego Inc. (San Diego, California) |
ASSIGNEE(S) | ALERE SAN DIEGO, INC. (San Diego, California) |
INVENTOR(S) | Alexander Schenk zu Schweinsberg (Jena, Germany); Austin Matthew Derfus (Solana Beach, California); Justin Davidson (San Diego, California); Karthikeyan Kumaravadivelu (San Diego, California); Maulik Vinod Patel (La Crescenta, California); Olaf Piepenburg (Saffron Walden, United Kingdom); Catherine Jean Greenwood (Sawbridgeworth, United Kingdom); Oliver Nentwich (Cambridge, United Kingdom) |
ABSTRACT | A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers. |
FILED | Tuesday, February 27, 2018 |
APPL NO | 15/906899 |
ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2200/082 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) G01N 1/38 (20130101) G01N 35/00069 (20130101) G01N 2001/028 (20130101) G01N 2035/00158 (20130101) G01N 2035/1034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633324 | Bazan et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
INVENTOR(S) | Nicolas G. Bazan (New Orleans, Louisiana); Nicos A. Petasis (Los Angeles, California) |
ABSTRACT | This disclosure provides compounds, pharmaceutical compositions, and methods of use for the prevention and treatment of inflammatory diseases or degenerative diseases including neurodegenerative diseases. Embodiments of the present disclosure provide compounds related to very long chain polyunsaturated fatty acids, pharmaceutical compositions containing the provided compounds, and methods of treating a subject with a condition or disease using provided compounds or pharmaceutical compositions. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/549676 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/202 (20130101) A61K 31/232 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 29/00 (20180101) Acyclic or Carbocyclic Compounds C07C 57/03 (20130101) Original (OR) Class C07C 59/42 (20130101) C07C 69/587 (20130101) C07C 69/732 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/10 (20130101) C07F 9/106 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633348 | Treon et al. |
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FUNDED BY |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Steven P. Treon (Jamaica Plain, Massachusetts); Sara Jean Buhrlage (Somerville, Massachusetts); Nathanael S. Gray (Boston, Massachusetts); Li Tan (Shanghai, China PRC); Guang Yang (Natick, Massachusetts) |
ABSTRACT | The present invention provides compounds of any one of Formulae (A), (I-11), (II), and (V) (e.g., compounds of Formula (A-1)-(A-18)), and methods for treating Waldenström's macroglobulinemia (WM) and other B cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. Also provided are methods to treat B cell neoplasms using the compounds in combination with inhibitors of Bruton's tyrosine kinase (BTK), interleukin-1 receptor-associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 4 (IRAK4), bone marrow on X chromosome kinase (BMX), phosphoinositide 3-kinase (PI3K), transforming growth factor b-activated kinase-1 (TAK1), and/or a Src family kinase. |
FILED | Tuesday, December 19, 2017 |
APPL NO | 15/847430 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) Original (OR) Class C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 413/12 (20130101) C07D 417/04 (20130101) C07D 487/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633370 | Huryn et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); National Institutes of Health, A Component of the U.S. Department of Health and Human Services (Bethesda, Maryland); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); National Institutes of Health, A Component of the U.S. Department of Health and Human Services (Bethesda, Maryland); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Donna M. Huryn (Allentown, New Jersey); Peter Wipf (Pittsburgh, Pennsylvania); Matthew G. LaPorte (Pittsburgh, Pennsylvania); Raffaele Colombo (Pittsburgh, Pennsylvania); Marina Kovaliov (Pittsburgh, Pennsylvania); Chaemin Lim (Pittsburgh, Pennsylvania); Celeste Natalie Alverez (Pittsburgh, Pennsylvania); Zhizhou Yue (Pittsburgh, Pennsylvania); Lalith Palitha Samankumara (Pittsburgh, Pennsylvania); Alexander Julian Chatterley (Pittsburgh, Pennsylvania); Yongzhao Yan (Pittsburgh, Pennsylvania); Mary Liang (Pittsburgh, Pennsylvania); Neal J. Green (Newton, Massachusetts); Eric T. Baldwin (Upper Holland, Pennsylvania); William J. Moore (Hagerstown, Maryland); Michelle Arkin (San Francisco, California); R. Jeffrey Neitz (Oakland, California); Kean-Hooi Ang (Oakland, California); Clifford Bryant (Oakland, California); Stacie Bulfer (Oakland, California) |
ABSTRACT | The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97. |
FILED | Thursday, October 20, 2016 |
APPL NO | 15/769987 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/10 (20130101) C07D 401/14 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 413/14 (20130101) C07D 417/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633374 | Spiegel et al. |
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FUNDED BY |
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APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
INVENTOR(S) | David Spiegel (New Haven, Connecticut); Anthony Rullo (Hamilton, Canada) |
ABSTRACT | The present invention relates to chimeric (including bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic cancer where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells. The compounds bind to the urokinase-type plasminogen activator receptor (uPAR) on the surface of a cancer cell, including a metastatic cancer cell, and consequently recruit native antibodies of the patient or subject where the antibodies can selectively degrade and/or deactivate targeted cancer cells through antibody-dependent cellular phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) against a large number and variety of cancers, thus providing cancer cell death and an inhibition of growth, elaboration and/or metastasis of the cancer, including remission and cure of the patient's cancer. |
FILED | Tuesday, February 06, 2018 |
APPL NO | 15/890040 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/451 (20130101) A61K 31/451 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 211/60 (20130101) C07D 413/04 (20130101) Original (OR) Class Peptides C07K 16/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633385 | Janda et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
INVENTOR(S) | Kim D. Janda (La Jolla, California); Nicholas T. Jacob (San Diego, California); Jonathan W. Lockner (San Diego, California) |
ABSTRACT | There are disclosed imidazolinopyrimidinone compounds that have activity to induce TRAIL gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of Formula I herein. |
FILED | Wednesday, March 20, 2019 |
APPL NO | 16/359633 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633404 | Klenc et al. |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Jeffrey Klenc (Atlanta, Georgia); Malgorzata Lipowska (Atlanta, Georgia); Andrew Taylor (Atlanta, Georgia) |
ABSTRACT | This disclosure relates to compositions comprising substituted iminodiacetic acid ligands and metal tricarbonyl complexes containing the ligands and derivatives thereof. In certain embodiments, the metal tricarbonyl complexes are used as radioisotope tracers such as renal tracers. In certain embodiments, the metal complexes comprise 99mTc or Re. In certain embodiments, the ligands are substituted with a fluorine, a fluorine-18 (F18) radioisotope, or other radionuclide. |
FILED | Thursday, March 10, 2016 |
APPL NO | 15/557453 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/4057 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 51/0402 (20130101) A61K 51/0478 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/004 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 13/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/5088 (20130101) G01N 2800/347 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633411 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Zhijian Chen (Dallas, Texas); Lijun Sun (Dallas, Texas); Jiaxi Wu (Dallas, Texas); Heping Shi (Dallas, Texas); Chuo Chen (Dallas, Texas) |
ABSTRACT | Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics. |
FILED | Monday, November 18, 2019 |
APPL NO | 16/687356 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7084 (20130101) A61K 39/39 (20130101) A61K 2039/55511 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/6876 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/573 (20130101) G01N 2333/9015 (20130101) G01N 2333/9125 (20130101) G01N 2400/00 (20130101) G01N 2500/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633417 | McIntosh |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
INVENTOR(S) | J. Michael McIntosh (Salt Lake City, Utah) |
ABSTRACT | The present disclosure describes analog conotoxin peptides of the α-contoxin peptide RgIA. These analog conotoxin peptides block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain, inflammatory conditions, inflammation, and/or cancer. |
FILED | Friday, May 30, 2014 |
APPL NO | 14/894967 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/43504 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633422 | Kawaoka et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Jihui Ping (Madison, Wisconsin) |
ABSTRACT | A vector, composition and method to improve influenza virus replication by inhibiting miRNA lec-7C binding to influenza virus mRNA and/or cRNA. |
FILED | Wednesday, June 01, 2016 |
APPL NO | 15/170556 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/525 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633424 | Mohammadi et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
ABSTRACT | The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF19 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
FILED | Wednesday, February 14, 2018 |
APPL NO | 15/896469 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class C07K 14/501 (20130101) C07K 14/503 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633425 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | SILVER CREEK PHARMACEUTICALS, INC. (San Francisco, California) |
ASSIGNEE(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
INVENTOR(S) | Laura D. J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Los Angeles, California); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Tuesday, July 03, 2018 |
APPL NO | 16/026319 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/33 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633441 | Adusumilli et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
FILED | Friday, December 02, 2016 |
APPL NO | 15/368278 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633447 | Dimitrov et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (the Government) (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Tianlei Ying (Shanghai, China PRC) |
ABSTRACT | Fc domains and CH3 domains are disclosed that bind the neonatal Fc (FcRn) receptor and are at least 99% monomeric. Monomeric Fc domain molecules and CH3 domain molecules are disclosed herein that include a monomeric Fc domain or a monomeric CH3 domain and an effector molecule. In some embodiments, the monomeric Fc or monomeric CH3 domain include amino acid substitutions and/or CDR insertions in the beta strands such that they specifically bind an antigen. Methods for using these monomeric Fc domains, monomeric CH3 domains, monomeric Fc domain molecules and CH3 domain molecules are also provided. |
FILED | Tuesday, May 09, 2017 |
APPL NO | 15/590981 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/005 (20130101) C07K 16/00 (20130101) C07K 16/283 (20130101) Original (OR) Class C07K 16/1045 (20130101) C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/64 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2318/20 (20130101) C07K 2319/30 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16111 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/573 (20130101) G01N 33/6863 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633450 | Kohrt et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Holbrook Kohrt (San Francisco, California); Roch Houot (Rennes, France); Ronald Levy (Stanford, California); Arash Ash Alizadeh (San Mateo, California); Matthew J. Goldstein (Hillsborough, California); James Torchia (Stanford, California) |
ABSTRACT | Methods are provided to enhance the efficacy of antibody therapy directed to tumor cells. |
FILED | Friday, August 04, 2017 |
APPL NO | 15/669418 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Peptides C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) C07K 16/2887 (20130101) C07K 16/2893 (20130101) C07K 16/2896 (20130101) Original (OR) Class C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3046 (20130101) C07K 16/3069 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/70578 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633636 | Shah et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Khalid Shah (Andover, Massachusetts); Kaoru Tamura (Tokyo, Japan); Hiroaki Wakimoto (Newton, Massachusetts) |
ABSTRACT | Disclosed herein is a recombinant oncolytic virus comprising a nucleic acid sequence encoding tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). One such oncolytic virus is oHSV. One form of TRAIL contained within the oncolytic virus is a secreted form of TRAIL. Examples of various forms of oHSV and secreted TRAIL are disclosed therein. Also disclosed are host cells and therapeutic formulations comprising the recombinant oncolytic virus. Also disclosed are methods of treating cancer in a subject by administering a therapeutic formulation comprising the recombinant oncolytic virus to the subject. |
FILED | Tuesday, December 05, 2017 |
APPL NO | 15/832109 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) A61K 38/19 (20130101) Peptides C07K 14/525 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2710/16632 (20130101) C12N 2710/16642 (20130101) C12N 2710/16671 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633642 | Joung et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts); Vikram Pattanayak (Wellesley, Massachusetts) |
ABSTRACT | Engineered CRISPR-Cas9 nucleases with improved specificity and their use in genomic engineering, epigenomic engineering, genome targeting, and genome editing. |
FILED | Tuesday, October 09, 2018 |
APPL NO | 16/155808 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/90 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2800/22 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633648 | Seelig et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Georg Seelig (Seattle, Washington); Anna Kuchina (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
ABSTRACT | Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers. |
FILED | Friday, February 10, 2017 |
APPL NO | 15/430108 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class C12N 15/1065 (20130101) C12N 15/1065 (20130101) C12N 15/1068 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2525/191 (20130101) C12Q 2563/103 (20130101) C12Q 2563/179 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633653 | Khvorova et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Mehran Nikan (Boston, Massachusetts); Matthew Hassler (Worcester, Massachusetts); Maire Osborn (Boston, Massachusetts); Reka Haraszti (Boston, Massachusetts); Andrew Coles (Boston, Massachusetts); Anton Turanov (Boston, Massachusetts); Neil Aronin (Newtonville, Massachusetts) |
ABSTRACT | Provided herein are self-delivering oligonucleotides that are characterized by efficient RISC entry, minimum immune response and off-target effects, efficient cellular uptake without formulation, and efficient and specific tissue distribution. |
FILED | Friday, August 12, 2016 |
APPL NO | 15/236051 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/554 (20170801) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633655 | Kay et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Mark A. Kay (Los Altos, California); Hak Kyun Kim (Palo Alto, California); Shengchun Wang (Union City, California) |
ABSTRACT | The present invention features compositions and methods relating to tRNA-derived small RNAs (tsRNAs). Provided herein are oligonucleotide compositions that are complementary to tsRNAs, in particular leuCAGtsRNA, and methods of using the oligonucleotides for the regulation of respective tsRNA. Further provided are methods of inducing apoptosis through the inhibition of leuCAGtsRNA. |
FILED | Thursday, July 21, 2016 |
APPL NO | 15/216546 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/606 (20130101) A61K 31/606 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/712 (20130101) A61K 31/712 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/113 (20130101) C12N 2310/341 (20130101) C12N 2310/3231 (20130101) C12N 2310/3231 (20130101) C12N 2320/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633662 | Pillay et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Oregon Health and Science University (Portland, Oregon) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Sirika Pillay (Hayward, California); Jan Carette (Palo Alto, California); Michael Stewart Chapman (Lake Oswego, Oregon); Nancy Meyer (Portland, Oregon); Andreas Puschnik (Palo Alto, California); Omar Davulcu (Portland, Oregon) |
ABSTRACT | Compositions and methods are provided for modulating adeno-associated virus (AAV) infection. For example, compositions and methods are provided for enhancing permissiveness of a target cell to AAV infection (e.g., by increasing levels of AAVR (KIAA0319L) in the cell), for reducing permissiveness of a target cell to AAV infection (e.g., by reducing levels of AAVR in the cell), and for nucleic acid delivery (e.g., by (i) increasing permissiveness of a target cell to AAV infection, e.g., by increasing the amount of AAVR in the cell; and (ii) contacting the target cell with an AAV particle that includes a nucleic acid of interest). Also provided are screening methods and kits for practicing the methods of the disclosure. |
FILED | Wednesday, November 09, 2016 |
APPL NO | 15/774223 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 15/625 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 15/8509 (20130101) C12N 2015/859 (20130101) C12N 2015/8581 (20130101) C12N 2310/14 (20130101) C12N 2330/50 (20130101) C12N 2710/10032 (20130101) C12N 2750/14152 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633675 | Ajikumar et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
INVENTOR(S) | Parayil K. Ajikumar (Cambridge, Massachusetts); Gregory Stephanopoulos (Winchester, Massachusetts); Heng Phon Too (Singapore, Singapore) |
ABSTRACT | The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids. |
FILED | Tuesday, July 10, 2018 |
APPL NO | 16/031509 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class C12P 7/42 (20130101) C12P 9/00 (20130101) C12P 15/00 (20130101) C12P 17/02 (20130101) C12P 19/56 (20130101) C12P 23/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633695 | Vo-Dinh et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Tuan Vo-Dinh (Chapel Hill, North Carolina); Hsin-Neng Wang (Durham, North Carolina); Andrew Fales (Durham, North Carolina) |
ABSTRACT | Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesirable cells in a subject. |
FILED | Tuesday, September 22, 2015 |
APPL NO | 14/861353 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 2525/301 (20130101) C12Q 2563/137 (20130101) C12Q 2563/155 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633704 | Johnson |
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FUNDED BY |
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APPLICANT(S) | Raymond M. Johnson (Branford, Connecticut) |
ASSIGNEE(S) | |
INVENTOR(S) | Raymond M. Johnson (Branford, Connecticut) |
ABSTRACT | A previously unknown T cell receptor (TCR) activation pathway dependent on the aryl hydrocarbon receptor conferring resistance to calcineurin inhibitors and mTOR inhibitors is disclosed, including application of this pathway to the diagnosis and treatment of certain disease states refractory to treatment with calcineurin inhibitors. This alternative TCR activation pathway uniquely exists in a subset of CD8 T cells expanded in the setting of chronic rejection or rheumatoid arthritis. Expansion of this newly discovered calcineurin and mTOR inhibitor resistant CD8 T cell subset in humans can be quantified by measuring levels of certain biomarkers in the circulating CD8 T cell pool, such as Pla2g4a, to diagnose disease states mediated thereby. Additionally, methods for diagnosing ongoing active inflammation mediated by this resistant CD8 T cell subset in either chronic rejection or rheumatoid arthritis are provided, which comprise measuring levels of the biomarker Scin in the circulating CD8 T cell pool. |
FILED | Monday, July 25, 2016 |
APPL NO | 15/218141 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/577 (20130101) G01N 33/5047 (20130101) G01N 33/6893 (20130101) G01N 2333/47 (20130101) G01N 2800/24 (20130101) G01N 2800/52 (20130101) G01N 2800/102 (20130101) G01N 2800/245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633766 | Haff et al. |
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FUNDED BY |
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APPLICANT(S) | University of Central Oklahoma (Edmond, Oklahoma) |
ASSIGNEE(S) | University of Central Oklahoma (Edmond, Oklahoma) |
INVENTOR(S) | Maurice Haff (Edmond, Oklahoma); Morshed Khandaker (Edmond, Oklahoma); William Paul Snow (Edmond, Oklahoma) |
ABSTRACT | An apparatus for collecting cross-aligned fiber threads, comprising an elongated assembly having a plurality of segments including at least a first segment, a second segment, and an intermediate segment, the first segment positioned at one end of the intermediate segment and the second segment positioned at an opposite end of the intermediate segment, each segment being electrically chargeable; an electrically chargeable emitter for electrospinning nanoscale fiber streams comprising charged fiber branches, the emitter having a tip positioned offset and between an edge of the first segment and an edge of the second segment; a support structure for rotating the elongated assembly about a longitudinal axis and applying an electrical charge to at least the edges of the first and second segment; at least one electrically chargeable steering electrode for attracting fiber streams, the at least one steering electrode chargeable with an electrical polarity opposing a charge applied to the emitter. |
FILED | Thursday, July 11, 2019 |
APPL NO | 16/508620 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/34 (20130101) D01D 5/0084 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) D10B 2509/022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634587 | Tseng et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Hsian-Rong Tseng (Los Angeles, California); Mitch A. Garcia (Malibu, California); Min Song (Los Angeles, California); Libo Zhao (Los Angeles, California); Shuang Hou (Los Angeles, California); Tom Lee (Redondo Beach, California) |
ABSTRACT | A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip. |
FILED | Monday, April 09, 2018 |
APPL NO | 15/948495 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 9/527 (20130101) B01L 2200/027 (20130101) B01L 2200/0647 (20130101) B01L 2300/0609 (20130101) B01L 2300/0816 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) Original (OR) Class G01N 1/286 (20130101) G01N 1/4077 (20130101) G01N 33/574 (20130101) G01N 33/56966 (20130101) G01N 2001/284 (20130101) G01N 2001/2886 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634637 | Potyrailo et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Cheryl Margaret Surman (Albany, New York); Binil Kandapallil (Mechanicville, New York) |
ABSTRACT | Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over the LCR circuit. The sensing material includes a coordination compound of a ligand and a metal nanoparticle. The coordination compound has the formula: (X)n-M, where X includes an alkylamine group having the formula (R—NH2), an alkylphosphine having the formula (R3—P), an alkylphosphine oxide having the formula (R3P═O), an alkyldithiocarbamate having the formula (R2NCS2), an alkylxanthate having the formula (ROCS2), or any combination thereof, R includes an alkyl group, n is 1, 2, or 3, and M includes the metal nanoparticle of gold, silver, platinum, palladium, alloys thereof, highly conductive metal nanoparticles, or any combination thereof. The sensing material is configured to allow selective detection of at least six different analyte fluids from an analyzed fluid mixture. |
FILED | Thursday, October 26, 2017 |
APPL NO | 15/794815 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/025 (20130101) G01N 27/3278 (20130101) Original (OR) Class G01N 33/48792 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634677 | Erickson et al. |
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FUNDED BY |
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APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Craig Erickson (Wyoming, Ohio); Debomoy Lahiri (Brownsburg, Indiana) |
ABSTRACT | Studies in mouse models of Fragile X and preliminary studies in human youth demonstrate that ERK1/2 is biomarker useful to monitoring the treatment of people diagnosed with ASD. Results reported herein demonstrate that acamprosate has the ability to reduce levels of ERK1/2 activation associated with many of the symptoms of ASD. Accordingly, in addition to its utility as a diagnostic marker for ASD ERK1/2 activation levels can be used to monitory patients treated with acamprosate. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 15/029596 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/185 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/48 (20130101) G01N 2333/4709 (20130101) G01N 2333/91205 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) G01N 2800/2814 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634685 | Nahm et al. |
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FUNDED BY |
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APPLICANT(S) | The UAB Research Foundation (Birmingham, Alabama); Fundacao Oswaldo Cruz (Rio de Janeiro, Brazil); Instituto Adolfo Lutz (Sao Paulo, Brazil) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); Fundacao Oswaldo Cruz (Rio de Janeiro, Brazil) |
INVENTOR(S) | Moon H. Nahm (Birmingham, Alabama); Jisheng Lin (Vestavia Hills, Alabama); Angela P. Brandao (Sao Paulo, Brazil); Maria Cristina Brandileone (Sao Paulo, Brazil) |
ABSTRACT | Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}. This new serotype may be included in pneumococcal vaccines. |
FILED | Monday, October 02, 2017 |
APPL NO | 15/723136 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/715 (20130101) A61K 39/092 (20130101) Peptides C07K 16/1275 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) Polysaccharides; Derivatives Thereof C08B 37/006 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/14 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) Original (OR) Class G01N 33/56944 (20130101) G01N 2333/315 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634742 | Garraud et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Nicolas Garraud (Gainesville, Florida); Carlos Rinaldi (Gainesville, Florida); David P. Arnold (Gainesville, Florida) |
ABSTRACT | Disclosed are various embodiments for a system configured to characterize a magnetic response of a sample. The system can comprise an electrical source configured to generate a time-varying current supply, an excitation coil system coupled to the electrical source to generate a time-vary magnetic field for application to a sample, and a sensing coil system that senses a magnetic response of the sample in response to the time-varying magnetic field. The sensing coil system can comprise a pick-up coil and a balancing coil that can be translated or rotated. The balancing coil configured to cancel a feed-through induction signal. In another embodiment, the sensing coil system can comprise an adjustable fine-tuning coil that is configured to modify an effect of the cancellation of the feed-through induction signal. |
FILED | Friday, October 07, 2016 |
APPL NO | 15/766638 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0515 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1276 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634747 | Majewski et al. |
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FUNDED BY |
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APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
INVENTOR(S) | Stanislaw Majewski (Morgantown, West Virginia); James Proffitt (Newport News, Virginia); James Lewis (Morgantown, West Virginia); Julie Brefczynski-Lewis (Morgantown, West Virginia); Alexander Stolin (Morgantown, West Virginia) |
ABSTRACT | A Positron Emission Tomography (“PET”) insert for use with a Magnetic Resonance Imaging (“MRI”) scanning device, the PET insert including a plurality of photodetector modules provided adjacent each other in an array, the plurality of photodetector modules configured for placement adjacent a body of a patient and sized to be received in a magnetic bore of the MRI scanning device with the patient, the photodetector modules providing detection of gamma annihilation photons, and a Radio Frequency (“RF”) coil provided between the patient and the plurality of photodetector modules. Each of the plurality of photodetector modules includes a pixelated scintillator array provided for alignment adjacent the patient's body, and a shielding block including silicon photomultiplier pads and passive electronic circuitry only. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/827557 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/481 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/1603 (20130101) G01T 1/2985 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634899 | Gopinath et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
INVENTOR(S) | Juliet T. Gopinath (Boulder, Colorado); Emily A. Gibson (Boulder, Colorado); Victor M. Bright (Boulder, Colorado); Richard Weir (Longmont, Colorado); Diego Restrepo (Littleton, Colorado); Baris Ozbay (Denver, Colorado) |
ABSTRACT | The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques. |
FILED | Thursday, January 22, 2015 |
APPL NO | 15/113303 |
ART UNIT | 2486 — Recording and Compression |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/14 (20130101) G02B 6/06 (20130101) G02B 21/006 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) G02B 23/26 (20130101) G02B 23/243 (20130101) Original (OR) Class G02B 23/2446 (20130101) G02B 23/2469 (20130101) G02B 26/005 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 2005/2255 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637575 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Chi Zhang (Madison, Wisconsin) |
ABSTRACT | A system for identifying the location of the mobile device uses standard fluorescent light fixtures commonly found in indoor environments and detects minor variations in the light output of those fixtures caused by normal manufacturing variation. These variations are catalogued as identifying fingerprints together with location of the light fixtures to provide for navigation. |
FILED | Wednesday, May 25, 2016 |
APPL NO | 15/164195 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/116 (20130101) Original (OR) Class H04B 10/1141 (20130101) Wireless Communication Networks H04W 4/02 (20130101) H04W 4/024 (20180201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10638112 | Shechtman et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Yoav Shechtman (Santa Clara, California); William E. Moerner (Stanford, California); Lucien Weiss (Los Angeles, California); Steffen J. Sahl (Göttingen, Germany) |
ABSTRACT | Various embodiments include an apparatus including a phase mask and circuitry. The phase mask is configured and arranged with optics in an optical path to modify a shape of light, passed from an object. The shape modification characterizes the light as having two lobes with a lateral distance that changes along a line, having a first orientation, as a function of an axial proximity of the object to a focal plane, and with the line having a different orientation depending on whether the object is above or below the focal plane. The circuitry is configured and arranged to generate a three-dimensional image from light detected at the image plane, by using the modified shape to provide depth-based characteristics of the object. |
FILED | Thursday, January 17, 2019 |
APPL NO | 16/250483 |
ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0056 (20130101) G02B 21/0064 (20130101) G02B 26/06 (20130101) Pictorial Communication, e.g Television H04N 13/161 (20180501) H04N 13/214 (20180501) H04N 13/218 (20180501) Original (OR) Class H04N 13/271 (20180501) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 10631877 | Murphy et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia); The United States of AMerica, as represented by the Secretary of the Defense (Washington, District of Columbia) |
INVENTOR(S) | Ryan Murphy (Columbia, Maryland); Ehsan Basafa (Baltimore, Maryland); Mehran Armand (Fulton, Maryland); Chad Gordon (Lutherville, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland) |
ABSTRACT | Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating. |
FILED | Wednesday, November 26, 2014 |
APPL NO | 15/100241 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632030 | Powell |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Timothy E Powell (Temecula, California) |
ABSTRACT | A reconfigurable portable load bearing structure which can be configured into an extended load bearing configuration or a collapsed configuration, comprising of a first, second and third plurality of rail segments that are each rotatably coupled together and a plurality of support segments or pads which are configured to selectively couple and latch into one of a plurality of positions on said first, second and third plurality of rail segments. |
FILED | Wednesday, December 21, 2016 |
APPL NO | 15/386510 |
ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 1/02 (20130101) A61G 1/003 (20130101) A61G 1/04 (20130101) A61G 1/007 (20130101) A61G 1/013 (20130101) Original (OR) Class A61G 7/103 (20130101) Construction of Bridges, or Viaducts; Assembly of Bridges E01D 15/133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632143 | McCarthy et al. |
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FUNDED BY |
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APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
ASSIGNEE(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
INVENTOR(S) | Simon McCarthy (Portland, Oregon); Barbara McGrath (Portland, Oregon); Sam Kuhn (Portland, Oregon); Jess Kimball (Portland, Oregon); Michael Stolten (New Orleans, Louisiana); Amanda Bennett (New Orleans, Louisiana) |
ABSTRACT | The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid. Chitosan materials can be mixed in solution with one or more of other hydrophilic polymers to create compositional heterogeneity and pharmaceutical agents to achieve controlled release of the agent(s) from the final forms at the site of application. |
FILED | Tuesday, February 13, 2018 |
APPL NO | 15/895677 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/70 (20130101) A61K 9/1652 (20130101) A61K 9/1694 (20130101) A61K 31/722 (20130101) Original (OR) Class A61K 47/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632384 | Stacy et al. |
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FUNDED BY |
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APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
INVENTOR(S) | E. Webb Stacy (Andover, Massachusetts); Kevin Sullivan (Lexington, Massachusetts); Paul Picciano (Windham, New Hampshire); Can Keskin (Gloucester, Massachusetts) |
ABSTRACT | Processor based systems and methods of defining a scenario event comprising the steps of identifying an event having an event attribute and generalizing the event attribute to define a generalized event whereby the generalized event is the scenario event. In some embodiments, the steps further comprise identifying a first and second event, generalizing a first and second event attribute to define a first and second generalized event and connecting the first and second generalized event in a continuous envelope to create a scenario envelope. Processor based systems and methods of monitoring an activity comprising the steps of monitoring an activity having an activity attribute and comparing the activity attribute to an event envelope to determine a status of the activity relative to the event envelope. |
FILED | Wednesday, November 21, 2018 |
APPL NO | 16/198257 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/60 (20140902) Original (OR) Class A63F 2300/6009 (20130101) A63F 2300/8017 (20130101) Electric Digital Data Processing G06F 9/542 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633113 | Fisher et al. |
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FUNDED BY |
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APPLICANT(S) | AeroVironment, Inc. (Simi Valley, California) |
ASSIGNEE(S) | AEROVIRONMENT, INC. (Monrovia, California) |
INVENTOR(S) | Christopher Eugene Fisher (Leo, Indiana); John Peter Zwaan (Simi Valley, California); David R. Thompson (Simi Valley, California); Marc L. Schmalzel (Simi Valley, California); Karl R. Klingbiel (Simi Valley, California); Tyson R. Jensen (Simi Valley, California); Pavel Belik (Simi Valley, California); Eric James Aagaard (Los Angeles, California) |
ABSTRACT | Liquid dispensing assemblies including adhesive anchoring assemblies configured to adhere to a support surface external to a device such as a vehicle. An air vehicle includes (a) a fluid adhesive container assembly detachably attached to the air vehicle, wherein the fluid adhesive container assembly comprises: (i) an adhesive container comprising fluid adhesive; and (ii) one or more fibers, wherein the one or more fibers are configured, or a brush of fibers, or a fabric of fibers, is configured to conduct the fluid adhesive and to structurally support an adhesive bond between the one or more fibers and a surface; and (b) means for dispensing the fluid adhesive from the fluid adhesive container, to the one or more fibers. |
FILED | Tuesday, May 01, 2018 |
APPL NO | 15/968521 |
ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/48 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/18 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/12 (20130101) Original (OR) Class B64F 1/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) Y10T 156/1788 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633420 | Bishop et al. |
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FUNDED BY |
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APPLICANT(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
ASSIGNEE(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
INVENTOR(S) | Barney Bishop (Annandale, Virginia); Monique van Hoek (Centreville, Virginia); Ezra Myung Chul Chung (North Potomac, Maryland) |
ABSTRACT | Peptides having antimicrobial properties are described herein, as are compositions containing such peptides, and methods for using the peptides. |
FILED | Thursday, July 27, 2017 |
APPL NO | 16/316646 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/10 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 2300/25 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) A61P 31/04 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633441 | Adusumilli et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department Of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
FILED | Friday, December 02, 2016 |
APPL NO | 15/368278 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633643 | Pavlik et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Benjamin J. Pavlik (Lincoln, Nebraska); Paul Blum (Lincoln, Nebraska); Kevin Van Cott (Hickman, Nebraska) |
ABSTRACT | An engineered payload-delivery system includes a target cell binding unit, covalently bound to a pore forming unit, and a payload portion adapted with a region capable of non-covalently binding to the pore forming unit. The pore forming unit is derived from a particular sub-serotype of Clostridium toxin, while the payload region is derived from a different sub-serotype of Clostridium toxin. The disclosed chimeric protein-based composition is capable of specifically delivering payload to neural cells. |
FILED | Saturday, May 14, 2016 |
APPL NO | 15/574151 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 47/6415 (20170801) A61K 49/0056 (20130101) Peptides C07K 14/33 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class C12N 15/62 (20130101) Enzymes C12Y 204/02 (20130101) C12Y 304/24069 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633695 | Vo-Dinh et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Tuan Vo-Dinh (Chapel Hill, North Carolina); Hsin-Neng Wang (Durham, North Carolina); Andrew Fales (Durham, North Carolina) |
ABSTRACT | Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesirable cells in a subject. |
FILED | Tuesday, September 22, 2015 |
APPL NO | 14/861353 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 2525/301 (20130101) C12Q 2563/137 (20130101) C12Q 2563/155 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633718 | Dudt et al. |
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FUNDED BY |
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APPLICANT(S) | Philip Dudt (North Bethesda, Maryland); Roshdy George Barsoum (McLean, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Philip Dudt (North Bethesda, Maryland); Roshdy George Barsoum (McLean, Virginia) |
ABSTRACT | An apparatus and method for hardening and compacting an inner face of a cylindrical opening of a structure. The apparatus and method is directed towards the hardening and compaction of an elongated cylindrical opening by surrounding the inner face of the cylindrical opening with a glass tube, and initiating an explosive volume expansion of the glass. This in turn, creates a compressive force that acts on the inner face to compact and harden the surface. |
FILED | Friday, September 29, 2017 |
APPL NO | 15/720111 |
ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 26/00 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633726 | Chinella |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | John F. Chinella (Warwick, Maryland) |
ABSTRACT | A low alloy high nitrogen steel includes iron and, by weight 0.14-0.60% nitrogen (N); 0.08-0.28% carbon (C); 0.10-2.20% nickel (Ni); 0.25-2.00% manganese (Mn); 1.20-2.70% chromium (Cr); 0.45-1.50% tungsten (W); not more than 0.05% molybdenum (Mo); not more than 0.02% vanadium (V); not more than 0.60% silicon (Si); not more than 0.10% copper (Cu); not more than 0.02% titanium (Ti); not more than 0.02% niobium (Nb); not more than 0.008% aluminum (Al); and not more than 0.02% of any other element with not more than 0.10% total other elements, wherein cobalt (Co) is substitutable for any part of the nickel. |
FILED | Wednesday, August 16, 2017 |
APPL NO | 15/678573 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/0263 (20130101) C21D 2211/008 (20130101) Alloys C22C 38/001 (20130101) Original (OR) Class C22C 38/04 (20130101) C22C 38/30 (20130101) C22C 38/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633754 | Woodrow, III et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Thomas A. Woodrow, III (Lakeside, Texas); Jean A. Nielsen (Kent, Washington) |
ABSTRACT | The present disclosure generally relates to the field of tin electroplating. More specifically, the present disclosure relates to methods for mitigating tin whisker formation on tin-plated films and tin-plated surfaces by doping the tin with germanium. |
FILED | Friday, July 05, 2013 |
APPL NO | 13/935768 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/30 (20130101) Original (OR) Class C25D 3/60 (20130101) C25D 5/54 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12715 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633981 | Quach et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | San Quach (East Hartford, Connecticut); Tracy A. Propheter-Hinckley (Manchester, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut) |
ABSTRACT | A component for a gas turbine engine includes, among other things, an airfoil that includes a pressure sidewall and a suction sidewall that meet together at both a leading edge and a trailing edge, the airfoil extending radially from a platform to a tip, a tip pocket formed in the tip and terminating prior to the trailing edge, and one or more heat transfer augmentation devices formed in the tip pocket. |
FILED | Friday, June 01, 2018 |
APPL NO | 15/995884 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) F01D 5/147 (20130101) F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) F05D 2260/221 (20130101) F05D 2260/2212 (20130101) F05D 2260/2214 (20130101) F05D 2260/22141 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633990 | Olson et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Anders C. Olson (Bloomfield, Connecticut); Nicholas W. Kantany (Manchester, Connecticut) |
ABSTRACT | A vane strut assembly is disclosed, The vane strut assembly may include a first panel, a second panel, and a coupling mechanism that couples the first panel and the second panel to one another. The coupling mechanism may include a first fitting that is attached to the first panel, a second fitting that is attached to the second panel, and a cable disposed between the first fitting and the second fitting. |
FILED | Monday, January 08, 2018 |
APPL NO | 15/864341 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 9/04 (20130101) F01D 9/041 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633994 | Barker |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | William M. Barker (North Andover, Massachusetts) |
ABSTRACT | A seal assembly for a gas turbine engine according to an example of the present disclosure includes a seal segment. The seal segment includes a blade-sealing portion that provides an elongated slot, a flange that extends from the blade-sealing portion, and a hook that extends from the blade-sealing portion and is spaced from the flange. The hook has a surface that at least partially provides a cavity. A feather seal has an elongated portion and first and second legs which extend from the elongated portion. The first leg abuts the flange, the second leg is disposed in the cavity, and the elongated portion is disposed in the elongated slot. |
FILED | Wednesday, March 21, 2018 |
APPL NO | 15/927145 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) F01D 11/005 (20130101) Original (OR) Class F01D 11/08 (20130101) F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/55 (20130101) F05D 2240/57 (20130101) F05D 2250/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634005 | Petrillo et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Dalton C. Petrillo (Norwich, Connecticut); Christopher M. Juh (Rocky Hill, Connecticut) |
ABSTRACT | A flow metering and retention system includes a first disk that is annular in shape surrounding a centerline and extending axially along the centerline, a first coverplate axially rearward of the first disk with the first coverplate having an axially rearward extending arm, a second disk that is annular in shape surrounding the centerline and rearward of the first coverplate, a second coverplate at least partially between the first coverplate and the second disk; and a ring adjacent to the radially outer side of the slot of the second disk. The second disk has a slot into which the arm of the first coverplate extends with the slot having a radially outer side and a radially inner side, and the ring is configured to meter air flowing between the radially outer side of the slot and the arm of the first coverplate. |
FILED | Thursday, July 13, 2017 |
APPL NO | 15/649387 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/082 (20130101) F01D 5/3015 (20130101) F01D 11/00 (20130101) F01D 11/001 (20130101) F01D 11/16 (20130101) F01D 25/08 (20130101) Original (OR) Class F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/067 (20130101) F02C 7/00 (20130101) F02C 7/18 (20130101) F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/321 (20130101) F05D 2230/90 (20130101) F05D 2230/642 (20130101) F05D 2230/644 (20130101) F05D 2250/44 (20130101) F05D 2260/33 (20130101) F05D 2260/36 (20130101) F05D 2260/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634092 | Simpson et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Alex J. Simpson (Tolland, Connecticut); Robert T. Knowlton (Newington, Connecticut) |
ABSTRACT | Disclosed is a linkage assembly for a gas turbine engine having a link having a first end, a second end, and a rod extending therebetween, the first end having a first sliding bearing disposed within a first sliding bearing housing, a fastener comprising a first flange and a second flange, a pin extending between the first flange and the second flange, wherein the first sliding bearing is pivotally connected to the pin; and a biasing member secured between the first flange and the sliding bearing housing, the biasing member contacting the sliding bearing housing and biasing the link against rotation about a center axis for the rod of the link. |
FILED | Friday, September 08, 2017 |
APPL NO | 15/700042 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/04 (20130101) B64D 2027/268 (20130101) Jet-propulsion Plants F02K 1/06 (20130101) Original (OR) Class F02K 1/1207 (20130101) F02K 3/075 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/42 (20130101) F05D 2250/241 (20130101) F05D 2260/50 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 7/02 (20130101) F16C 11/02 (20130101) F16C 11/045 (20130101) F16C 11/0614 (20130101) F16C 2360/43 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634153 | Pinera et al. |
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FUNDED BY |
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APPLICANT(S) | Alex Pinera (Jupiter, Florida); Stephen M Brooks (Jupiter, Florida); Timothy J Miller (Jupiter, Florida) |
ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
INVENTOR(S) | Alex Pinera (Jupiter, Florida); Stephen M Brooks (Jupiter, Florida); Timothy J Miller (Jupiter, Florida) |
ABSTRACT | A turbopump is formed from a metal additive manufacturing process in which both the housing and the impeller are formed as a single piece with the impeller trapped within the single piece housing. The impeller is formed with an axial bore and a shaft is secured by a tie bolt on one end to secure forward and aft bearings within the housing after the impeller and housing have been formed. |
FILED | Monday, June 06, 2016 |
APPL NO | 15/173773 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Jet-propulsion Plants F02K 9/46 (20130101) Non-positive-displacement Pumps F04D 17/08 (20130101) F04D 25/04 (20130101) F04D 29/043 (20130101) Original (OR) Class F04D 29/046 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634259 | Grayson et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Gary David Grayson (Issaquah, Washington); Christopher C. Veto (Huntington Beach, California); Victor John Barackman (Costa Mesa, California); Henry Rodriguez (Diamond Bar, California) |
ABSTRACT | Guide vane check valve assemblies and poppets for guide vane check valve assemblies are disclosed. A guide vane poppet includes an elongate central core configured to form a fluid seal with a valve body of the check valve assembly. The guide vane poppet additionally includes an elongate outer skirt and at least one guide vane radially extending between the elongate central core and the elongate outer skirt. A check valve assembly includes a valve body with a central cavity, an inlet to the central cavity, an outlet from the central cavity, and a spring seat, and further includes a spring and a poppet. The spring is oriented to press against the poppet and to urge a poppet-side sealing surface of the poppet into sealing engagement with a body-side sealing surface of the valve body. |
FILED | Friday, April 19, 2019 |
APPL NO | 16/389790 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/025 (20130101) F16K 15/026 (20130101) F16K 17/04 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/7938 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634466 | Bishop |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael L. Bishop (Norco, California) |
ABSTRACT | The invention relates to sealable short-pathlength liquid transmission cells for Fourier-transform infrared spectroscopy applications. In exemplary embodiments, a liquid transmission cell with transmissions sections uses horizontal tubing for inserting and removing fluids from the cell. Angling the tubing relative to a top face of the cell allows small amounts of entrapped air to rise out of the optical path without blocking spectroscopy measurements. The tubing is silver-soldered to the body of the transmission cell to make a leak-free connection. |
FILED | Friday, February 01, 2019 |
APPL NO | 16/265214 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/113 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/3577 (20130101) G01N 2021/0106 (20130101) G01N 2021/3595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634469 | Shipley et al. |
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FUNDED BY |
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APPLICANT(S) | AAI Corporation (Hunt Valley, Maryland) |
ASSIGNEE(S) | AAI Corporation (Hunt Valley, Maryland) |
INVENTOR(S) | Paul Andrew Shipley (Millers, Maryland); Joshua Stephen Ruck (Baltimore, Maryland); Benjamin Tyler Cole (Baltimore, Maryland); Brandon Scott Recchia (Parkton, Maryland); Cameron Mehdi Brand (Bel Air, Maryland); William Henry Engel, IV (Cockeysville, Maryland) |
ABSTRACT | A cased telescoped cartridge that includes a cylindrical case surrounding a projectile, a front end through which the projectile exits when the cased telescoped cartridge is fired, and a thermal protective insert located at the front end. The thermal protective insert insulates the cased telescoped cartridge from heat emanating from a barrel of a firearm into a chamber of a firearm when the cartridge is loaded into the chamber of the firearm. The thermal protective insert is made up of at least one thermally insulating material, and is integrated into the front end of the cased telescoped cartridge. |
FILED | Friday, March 01, 2019 |
APPL NO | 16/290125 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634474 | Blazek et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Benjamin M. Blazek (Ridgecrest, California); Lee R. Hardt (Ridgecrest, California); Carl A. Weinstein (Ridgecrest, California) |
ABSTRACT | Embodiments are directed to a shock mitigation device including a hollow fuze well having an inner surface and an outer surface. A plurality of vents are axially spaced at equal distance about the outer surface. A shock dampening liner is affixed to the inner surface. A shock dampening ring is concentric about the hollow fuze well. |
FILED | Thursday, June 06, 2019 |
APPL NO | 16/433023 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 39/14 (20130101) F42B 39/20 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634499 | Ayazi et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Farrokh Ayazi (Atlanta, Georgia); Haoran Wen (Atlanta, Georgia) |
ABSTRACT | An inertial measurement apparatus has mechanically bendable beams that have an isosceles trapezoid cross-section. The apparatus has a resonant member having a perimeter at least partially defined by a sidewall slanted at a first angular value and at least one electrode disposed adjacent, and parallel, to the sidewall and separated therefrom by a capacitive gap. |
FILED | Monday, June 13, 2016 |
APPL NO | 15/743449 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5642 (20130101) G01C 19/5747 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/241 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) G01P 15/125 (20130101) G01P 2015/0848 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634557 | Khorasaninejad et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
INVENTOR(S) | Mohammadreza Khorasaninejad (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts); Wei Ting Chen (Cambridge, Massachusetts); Jaewon Oh (Cambridge, Massachusetts) |
ABSTRACT | A meta-lens having a phase profile includes a substrate and a plurality of nanostructures disposed on the substrate. The nanostructures together define the phase profile of the meta-lens. The phase profile achieves an off-axis focus. Each nanostructure is designed according to at least one design parameter of the nanostructure that imparts a phase shift of light passing through the nanostructure. |
FILED | Friday, April 07, 2017 |
APPL NO | 16/091976 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/00 (20130101) G01J 3/18 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0256 (20130101) Optical Elements, Systems, or Apparatus G02B 3/08 (20130101) G02B 2207/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634665 | Iyer et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico); Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Rashi Iyer (Los Alamos, New Mexico); Jen-Huang Huang (Los Alamos, New Mexico); Pulak Nath (Los Alamos, New Mexico); Jennifer Harris (Los Alamos, New Mexico); John P. Wikswo, Jr. (Brentwood, Tennessee) |
ABSTRACT | Disclosed herein are embodiments of a device that can be used to mimic the biochemical and physiological actions of a lung organ. Also disclosed herein are embodiments of components that are included in the device as well as methods of making and using the device. Further disclosed are platform device embodiments and various components used therein that can be used in combination with the lung organ devices disclosed herein. In some embodiments, the disclosed devices can be used to determine drug toxicity and also can be used with one or more disease models to determine methods of treating disease. |
FILED | Thursday, September 24, 2015 |
APPL NO | 15/513949 |
ART UNIT | 1799 — Printing/Measuring and Testing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2200/027 (20130101) B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2300/0887 (20130101) B01L 2400/0481 (20130101) B01L 2400/0633 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 5/067 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5014 (20130101) G01N 33/5064 (20130101) Original (OR) Class G01N 33/5082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634790 | Mullen et al. |
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FUNDED BY |
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APPLICANT(S) | Linda Mullen (Chesapeake Beach, Maryland); Robert Lee (Washington, District of Columbia); Justin Nash (Leonardtown, Maryland); Brandon Cochenour (Alexandria, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Linda Mullen (Chesapeake Beach, Maryland); Robert Lee (Washington, District of Columbia); Justin Nash (Leonardtown, Maryland); Brandon Cochenour (Alexandria, Virginia) |
ABSTRACT | An optical imaging system and method for use in a degraded visual environment is provided. A wideband modulated laser pulse is transmitted from a first location through a medium toward a target object. An input of the transmitted wideband modulated laser pulse is detected by an optical receiver. A target modulated laser pulse, reflected from the target object is detected by the optical receiver. The transmitted and reflected laser pulses are filtered by a bandpass filter, based on a predetermined modulated frequency range. The filtered transmitted and reflected laser pulses are digitized by an analog-digital converter. The digitized transmitted laser pulse is correlated with digitized reflected laser pulse by a digital matched filter, wherein the matched filter produces a passband matched filter output. A range of the target object is determined based on the matched filter output. |
FILED | Friday, January 13, 2017 |
APPL NO | 15/405993 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Original (OR) Class G01S 17/102 (20130101) Transmission H04B 10/5057 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634851 | Steinbrecher et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Gregory R. Steinbrecher (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
ABSTRACT | A method of nonblocking optical switching includes guiding a first optical beam from a first input to a first output via a first path through an optical switching fabric. The first path traverses a phase shifter disposed between a pair of cascaded Mach-Zehnder interferometers. The method also includes receiving a second optical beam for a second path intersecting with the first path through the optical switching fabric. The method also includes moving the first optical beam from the first path to a third path connecting the first input to the first output without intersecting the second path. The method also includes shifting a phase of the first optical beam, with the phase shifter, while moving the first optical beam from the first path to the third path to prevent the first optical beam from interfering with the second optical beam. |
FILED | Thursday, May 17, 2018 |
APPL NO | 15/982035 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/356 (20130101) Original (OR) Class G02B 6/3546 (20130101) G02B 6/29355 (20130101) Selecting H04Q 11/0005 (20130101) H04Q 2011/0015 (20130101) H04Q 2011/0035 (20130101) H04Q 2011/0047 (20130101) H04Q 2011/0052 (20130101) H04Q 2011/0058 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634938 | Fang et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusets Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Zhuoran Fang (Foshan, China PRC); Tian Gu (Fairfax, Virginia); Juejun Hu (Newton, Massachusetts); Junying Li (Somerville, Massachusetts); Yifei Zhang (Cambridge, Massachusetts) |
ABSTRACT | An alloy of GexSbySezTem includes atoms of Ge, Sb, Se, and Te that form a crystalline structure having a plurality of vacancies randomly distributed in the crystalline structure. The alloy can be used to construct an optical device including a first waveguide to guide a light beam and a modulation layer disposed on the first waveguide. The modulation includes the alloy of GexSbySezTem which has a first refractive index n1 in an amorphous state and a second refractive index n2, greater than the first refractive index by at least 1, in a crystalline state. The first waveguide and the modulation layer are configured to guide about 1% to about 50% of the light beam in the modulation layer when the alloy is in the amorphous state and guide no optical mode when the alloy is in the crystalline state. |
FILED | Friday, March 30, 2018 |
APPL NO | 15/941879 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Alloys C22C 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0623 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) G02F 1/0147 (20130101) Original (OR) Class G02F 1/225 (20130101) G02F 2001/212 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635490 | Bertran Monfort et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Ramon Bertran Monfort (Bronx, New York); Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Chen-Yong Cher (Port Chester, New York); Hans M. Jacobson (White Plains, New York); William J. Song (Atlanta, Georgia); Karthik V. Swaminathan (Ossining, New York); Augusto J. Vega (Astoria, New York); Liang Wang (Charlottesville, Virginia) |
ABSTRACT | An aspect includes optimizing an application workflow. The optimizing includes characterizing the application workflow by determining at least one baseline metric related to an operational control knob of an embedded system processor. The application workflow performs a real-time computational task encountered by at least one mobile embedded system of a wirelessly connected cluster of systems supported by a server system. The optimizing of the application workflow further includes performing an optimization operation on the at least one baseline metric of the application workflow while satisfying at least one runtime constraint. An annotated workflow that is the result of performing the optimization operation is output. |
FILED | Tuesday, November 24, 2015 |
APPL NO | 14/950934 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/543 (20130101) G06F 9/4887 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635761 | English et al. |
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FUNDED BY |
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APPLICANT(S) | ENERGID TECHNOLOGIES CORPORATION (Cambridge, Massachusetts) |
ASSIGNEE(S) | Energid Technologies Corporation (Cambridge, Massachusetts) |
INVENTOR(S) | James D. English (Alva, Florida); Ryan S. Penning (Madison, Wisconsin); Douglas E. Barker (Somerville, Massachusetts); James A. Bacon (Bourbonnais, Illinois) |
ABSTRACT | A method, computer program product, and computer system for configuring a stochastic simulation scenario, wherein the stochastic simulation scenario may include one or more variables without a complete probability distribution. The stochastic simulation scenario may be executed to generate one or more results of the stochastic simulation scenario. At least a portion of the one or more variables without the probability distribution may be optimized using one or more optimization metrics on the one or more results of the stochastic simulation scenario. |
FILED | Friday, April 29, 2016 |
APPL NO | 15/142157 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/23446 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 2201/0213 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 17/5095 (20130101) G06F 2217/10 (20130101) G06F 2217/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635971 | Chelian et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Suhas E. Chelian (San Jose, California); Matthias Ziegler (Agoura Hills, California); James Benvenuto (Beverly Hills, California); Jeffrey Lawrence Krichmar (Cardiff By the Sea, California); Randall C. O'Reilly (Boulder, Colorado); Rajan Bhattacharyya (Sherman Oaks, California) |
ABSTRACT | Described is a system for proactive and reactive cognitive control using a neural module. The system calculates, for each hypothesis of a set of hypotheses, a probability that an event will occur. The neural module comprises a plurality of neurons and includes the PC module, a prefrontal cortex (PFC) module, an anterior cingulate cortex (ACC) module, a locus coeruleus (LC) module, and a basal forebrain (BF) module. The set of hypotheses are related to tasks to be performed by a plurality of groups, each group having a corresponding hypothesis. For each probability, the system calculates a conflict value across all hypotheses with the ACC module, compares each conflict value to a predetermined threshold using the BF and LC modules. A determination is made whether to directly output the calculated probability or perform an additional probability calculation and output an updated probability. |
FILED | Tuesday, December 01, 2015 |
APPL NO | 14/955722 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 7/005 (20130101) G06N 20/00 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635989 | Blais et al. |
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FUNDED BY |
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APPLICANT(S) | SOCPRA Sciences et Génie S.E.C. (Sherbrooke, QC, Canada) |
ASSIGNEE(S) | SOCPRA Sciences et Génie s.e.c. (Sherbrooke, QC, Canada) |
INVENTOR(S) | Alexandre Blais (Sherbrooke, Canada); Baptiste Royer (Sherbrooke, Canada); Arne Loehre Grimsmo (Sherbrooke, Canada) |
ABSTRACT | A method and circuit QED implementation of a control-phase quantum logic gate UCP(θ)=diag[1,1,1, eiθ]. Two qubits Qi, two resonators Ra, Rb and a modulator. Q1 and Q2, each has a frequency ωqi and characterized by {circumflex over (σ)}zi. Ra is associated with Q1 and defined by a quantum non-demolition (QND) longitudinal coupling g1z{circumflex over (σ)}1z(â†+â). Rb is integrated into Ra, the QND second longitudinal coupling is defined by Ra as g2z{circumflex over (σ)}2z({circumflex over (b)}†+{circumflex over (b)}) or, when Rb is integrated into Ra, the QND second longitudinal coupling is defined by Ra as g2z{circumflex over (σ)}2z(â†+â) The modulator periodically modulates, at a frequency ωm during a time t, the longitudinal coupling strengths g1z and g2z with respective signals of respective amplitudes {tilde over (g)}1 and {tilde over (g)}2. Selecting a defined value for each of t, g1z and g2z determines θ to specify a quantum logical operation performed by the gate. Q1 and Q2 are decoupled when either one of g1z and g2z is to set to 0. |
FILED | Thursday, March 09, 2017 |
APPL NO | 16/068199 |
ART UNIT | 2824 — Semiconductors/Memory |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Static Stores G11C 11/44 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636127 | Fleizach |
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FUNDED BY |
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APPLICANT(S) | Gregory K. Fleizach (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Gregory K. Fleizach (San Diego, California) |
ABSTRACT | A method and system for bidirectional edge highlighting. A memory receives an original input image. A processor calculates edge intensity for each edge pixel in the original input image. The processor also identifies strong edges and attenuates said strong edges. The processor can further determine whether the attenuated strong edges should be bright or dark based on the intensity of the pixel in the original image. The processor applies bidirectional edge highlighting to the image based on the intensity of the pixel in the original image. The degree of darkness or brightness of the highlighting is based on the calculated edge intensity after strong edge attenuation. |
FILED | Tuesday, September 25, 2018 |
APPL NO | 16/141398 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 5/003 (20130101) Original (OR) Class G06T 5/30 (20130101) G06T 7/13 (20170101) G06T 7/40 (20130101) G06T 7/136 (20170101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636149 | Freeman et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William T. Freeman (Acton, Massachusetts); Frederic Durand (Somerville, Massachusetts); Tianfan Xue (Cambridge, Massachusetts); Michael Rubinstein (Somerville, Massachusetts); Neal Wadhwa (Mountain View, California) |
ABSTRACT | An apparatus according to an embodiment of the present invention enables measurement and visualization of a refractive field such as a fluid. An embodiment device obtains video captured by a video camera with an imaging plane. Representations of apparent motions in the video are correlated to determine actual motions of the refractive field. A textured background of the scene can be modeled as stationary, with a refractive field translating between background and video camera. This approach offers multiple advantages over conventional fluid flow visualization, including an ability to use ordinary video equipment outside a laboratory without particle injection. Even natural backgrounds can be used, and fluid motion can be distinguished from refraction changes. Embodiments can render refractive flow visualizations for augmented reality, wearable devices, and video microscopes. |
FILED | Tuesday, November 21, 2017 |
APPL NO | 15/819791 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) G01P 5/26 (20130101) Optical Elements, Systems, or Apparatus G02B 27/54 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/10021 (20130101) G06T 2207/10056 (20130101) G06T 2207/30241 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636485 | Zehnder et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Daniel M. Zehnder (Los Angeles, California); Jeong-Sun Moon (Moorpark, California) |
ABSTRACT | A method for time interleaved writing includes providing a phase change material (PCM) array, the PCM array comprising a plurality of phase change material areas arranged in a two dimensional array having rows and columns, selecting PCM areas to configure, and configuring the selected PCM areas. Selecting PCM areas to configure includes selecting PCM areas to configure in both the row and column dimensions that are separated by at least two PCM areas that are not selected to be configured. |
FILED | Monday, March 19, 2018 |
APPL NO | 15/925229 |
ART UNIT | 2824 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 13/0004 (20130101) G11C 13/0069 (20130101) Original (OR) Class G11C 2213/79 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636654 | Xia |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Fengnian Xia (Orange, Connecticut) |
ABSTRACT | A scalable approach for the synthesis of black phosphorus (BP) material thin films over large areas is described. A red phosphorus (RP) material thin film may be deposited on a substrate followed by conversion to a BP material thin film using high-pressure alone or high pressure and high temperature. A thin-film of dielectric material such as hexagonal boron nitride (hBN) can be formed on a RP material film before the conversion is performed to improve the crystalline quality and stability of the converted BP material. Surprisingly, an atomically sharp and defect-free interface can be formed between the converted BP material and hBN. The BP material has high crystalline uniformity and can be used to fabricate thin-film transistors and optoelectronic devices such as infrared photodetectors. |
FILED | Friday, April 06, 2018 |
APPL NO | 15/947202 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/006 (20130101) C01B 25/023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02422 (20130101) H01L 21/02521 (20130101) H01L 21/02631 (20130101) Original (OR) Class H01L 21/6835 (20130101) H01L 23/3157 (20130101) H01L 29/26 (20130101) H01L 29/786 (20130101) H01L 29/78696 (20130101) H01L 2221/68304 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636929 | McIntosh et al. |
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FUNDED BY |
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APPLICANT(S) | K. Alexander McIntosh (Groton, Massachusetts); David C. Chapman (Albuquerque, New Mexico); Joseph P. Donnelly (Carlisle, Massachusetts); Douglas C. Oakley (Natick, Massachusetts); Antonio Napoleone (Watertown, Massachusetts); Erik K. Duerr (Groton, Massachusetts); Simon Verghese (Arlington, Massachusetts); Richard D. Younger (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | K. Alexander McIntosh (Groton, Massachusetts); David C. Chapman (Albuquerque, New Mexico); Joseph P. Donnelly (Carlisle, Massachusetts); Douglas C. Oakley (Natick, Massachusetts); Antonio Napoleone (Watertown, Massachusetts); Erik K. Duerr (Groton, Massachusetts); Simon Verghese (Arlington, Massachusetts); Richard D. Younger (Cambridge, Massachusetts) |
ABSTRACT | An avalanche photodiode detector is provided with a substrate including an array of avalanche photodiodes. An optical interface surface of the substrate is arranged for accepting external input radiation. There is provided at least one cross-talk blocking layer of material including apertures positioned to allow external input radiation to reach photodiodes and including material regions positioned for attenuating radiation in the substrate that is produced by photodiodes in the array. Alternatively at least one cross-talk blocking layer of material is disposed on the optical interface surface of the substrate to allow external input radiation to reach photodiodes and attenuate radiation in the substrate that is produced by photodiodes in the array. At least one cross-talk filter layer of material can be disposed in the substrate adjacent to the photodiode structures, including a material that absorbs radiation in the substrate that is produced by photodiodes in the array. |
FILED | Friday, April 30, 2010 |
APPL NO | 12/771155 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/167 (20130101) H01L 27/1446 (20130101) H01L 31/107 (20130101) Original (OR) Class H01L 31/0352 (20130101) H01L 31/02005 (20130101) H01L 31/02162 (20130101) H01L 31/02327 (20130101) H01L 31/03046 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637090 | Bond et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Matthew L. Bond (San Diego, California); Yolanda M. Arias-Thode (San Diego, California); Kenneth E. Richter (San Diego, California); David B. Chadwick (San Diego, California); Lewis Hsu (Honolulu, Hawaii) |
ABSTRACT | A device for capturing energy, with an anode base, a rigid body, a pressure housing, a cathode array, and a wire. The anode base is connected to the rigid body, the pressure housing is connected to the rigid body, and the cathode array is connected to the rigid body. The first wire is electrically connected to the cathode array. The second wire is electrically connected to the anode base. |
FILED | Thursday, September 27, 2018 |
APPL NO | 16/143689 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8626 (20130101) H01M 8/16 (20130101) Original (OR) Class H01M 8/0247 (20130101) H01M 8/2475 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637586 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ASSIGNEE(S) | National Science Foundation (Alexandria, Virginia) |
INVENTOR(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ABSTRACT | Systems and methods for underwater communication using a MIMO acoustic channel. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder. |
FILED | Friday, August 25, 2017 |
APPL NO | 15/686390 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03057 (20130101) H04L 27/0008 (20130101) H04L 2025/03426 (20130101) H04L 2025/03636 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10638064 | Colonero et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Curtis Colonero (Shrewsbury, Massachusetts); Michael W. Kelly (North Reading, Massachusetts); Megan H. Blackwell (Winchester, Massachusetts); Lauren L. White (Burlington, Massachusetts) |
ABSTRACT | In time-delay-and-integrate (TDI) imaging, a charge-couple device (CCD) integrates and transfers charge across its columns. Unfortunately, the limited well depth of the CCD limits the dynamic range of the resulting image. Fortunately, TDI imaging can be implemented with a digital focal plane array (DFPA) that includes a detector, analog-to-digital converter (ADC), and counter in each pixel and transfer circuitry connected adjacent pixels. During each integration period in the TDI scan, each detector in the DFPA generates a photocurrent that the corresponding ADC turns into digital pulses, which the corresponding counter counts. Between integration periods, the DFPA transfers the counts from one column to the next, just like in a TDI CCD. The DFPA also non-destructively transfers some or all of the counts to a separate memory. A processor uses these counts to estimate photon flux and correct any rollovers caused by “saturation” of the counters. |
FILED | Wednesday, October 16, 2019 |
APPL NO | 16/654077 |
ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/355 (20130101) H04N 5/378 (20130101) H04N 5/2355 (20130101) H04N 5/3743 (20130101) H04N 5/23254 (20130101) H04N 5/23267 (20130101) H04N 5/35554 (20130101) Original (OR) Class H04N 5/35572 (20130101) H04N 5/37206 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10638634 | Elsasser et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Ryan Elsasser (Poughkeepsie, New York); William Risk (San Jose, California); Camillo Sassano (Durham, North Carolina); Matthew Butterbaugh (Rochester, Minnesota); Michael Good (Fountain, Minnesota) |
ABSTRACT | Rack-mountable assemblies are provided which include a cover configured to fixedly mount to a frame of an electronics rack, and a drawer configured to slidably mount to the frame adjacent to the cover to slide relative to the cover. When operatively mounted to the frame, the cover and drawer together define an enclosure for one or more electronic components. The assembly further includes an electromagnetic shielding structure to provide, at least in part, electromagnetic shielding at a gap between the cover and drawer when operatively positioned within the electronics rack. The electromagnetic shielding structure includes an electromagnetic shielding plate which overlies, at least in part, the gap between the cover and the drawer, and which self-adjusts with sliding of the drawer into the electronics rack to facilitate providing the electromagnetic shielding at the gap between the cover and the drawer. |
FILED | Friday, June 21, 2019 |
APPL NO | 16/448144 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/16 (20130101) H05K 7/1487 (20130101) Original (OR) Class H05K 7/1489 (20130101) H05K 9/0016 (20130101) H05K 9/0062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 10632400 | Rudisill et al. |
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FUNDED BY |
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APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
INVENTOR(S) | Tracy S. Rudisill (North Augusta, South Carolina); Fernando F. Fondeur (North Augusta, South Carolina); Lindsay E. Roy (Aiken, South Carolina); William E. Daniel, Jr. (North Augusta, South Carolina) |
ABSTRACT | The present invention is directed to a method for the separation of an actinide from another metal. The method comprises the following steps: (a) establishing a non-homogeneous magnetic field across a separation column containing a paramagnetic packing material and (b) providing a fluid containing the actinide and the another metal to the separation column wherein the fluid and the paramagnetic packing material are exposed to the non-homogeneous magnetic field. The non-homogeneous magnetic field is produced by a magnet having a first pole for magnetic interaction with a second pole of the magnet wherein the first pole has a different surface area than the second pole. The non-homogeneous magnetic field has a magnetic field gradient of about 500 lines/cm2/cm or more. In addition, the present invention is also directed to a method for the separation of one heavy metal from another heavy metal. |
FILED | Monday, December 11, 2017 |
APPL NO | 15/837726 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 15/1821 (20130101) B01D 15/3885 (20130101) Original (OR) Class Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/24 (20130101) C22B 7/005 (20130101) C22B 59/00 (20130101) C22B 60/04 (20130101) C22B 60/0252 (20130101) C22B 60/0295 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632418 | Blencoe et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); VIRGINIA MUSEUM OF NATURAL HISTORY FOUNDATION (Martinsville, Virginia) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | James G. Blencoe (Harriman, Tennessee); Donald A. Palmer (Oliver Springs, Tennessee); Lawrence M. Anovitz (Knoxville, Tennessee); James S. Beard (Martinsville, Virginia) |
ABSTRACT | In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide to produce a hydroxide of the metal formerly contained in the silicate; (b) reacting carbon dioxide with at least one of a caustic alkali-metal hydroxide and an alkali-metal silicate to produce at least one of an alkali-metal carbonate and an alkali-metal bicarbonate; and (c) reacting the metal hydroxide product of step (a) with at least one of the alkali-metal carbonate and the alkali-metal bicarbonate produced in step (b) to produce a carbonate of the metal formerly contained in the metal silicate of step (a). |
FILED | Wednesday, June 28, 2017 |
APPL NO | 15/635950 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/62 (20130101) Original (OR) Class B01D 2251/30 (20130101) B01D 2251/604 (20130101) B01D 2258/02 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/60 (20170801) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/24 (20130101) C01F 11/18 (20130101) C01F 11/181 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632436 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Sam W. Brown (Knoxville, Tennessee); Larry S. Spencer (Knoxville, Tennessee); Michael R. Phillips (Harriman, Tennessee); G. Louis Powell (Oak Ridge, Tennessee); Peggy J. Campbell (Clinton, Tennessee) |
ABSTRACT | A hydrogen, lithium, and lithium hydride processing apparatus includes a hot zone to heat solid-phase lithium hydride to form liquid-phase lithium hydride; a vacuum source to extract hydrogen and gaseous-phase lithium metal from the liquid-phase lithium hydride; a cold zone to condense the gaseous-phase lithium metal as purified solid-phase lithium metal; and a heater to melt the purified solid-phase lithium metal in the cold zone and form refined liquid-phase lithium metal in the hot zone. |
FILED | Thursday, May 11, 2017 |
APPL NO | 15/592289 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/002 (20130101) B01D 53/22 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/00 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 9/04 (20130101) C22B 9/006 (20130101) C22B 9/026 (20130101) C22B 26/12 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 17/001 (20130101) F27D 17/008 (20130101) F27D 2007/066 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/364 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632447 | Liu |
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FUNDED BY |
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APPLICANT(S) | Molecule Works Inc. (Richland, Washington) |
ASSIGNEE(S) | Molecule Works Inc. (Richland, Washington) |
INVENTOR(S) | Wei Liu (Richland, Washington) |
ABSTRACT | Design, fabrication, and usage of a reactor are presented for synthesis of structured materials from a liquid-phase precursor by heating. The structured materials are particles, membranes or films of micro-porous molecular sieve crystals such as zeolite and meso-porous materials. The precursor solution and structured materials in the reactor are uniformly heated by a planar heater with characteristic heat transfer dimension in the range of 3 mm to 10 cm. A planar heater having width and length at least three times of the characteristic heat transfer dimension provides at least one surface of uniform temperature distribution for heating purposes. Heating is conducted over a temperature range of 20 to 300° C. The planar heater can be heated by electrical power of by thermal fluid. |
FILED | Friday, December 28, 2018 |
APPL NO | 16/235655 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 67/0051 (20130101) B01D 69/10 (20130101) B01D 71/028 (20130101) B01D 2323/08 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/04 (20130101) B01J 19/247 (20130101) Original (OR) Class B01J 2219/00058 (20130101) B01J 2219/00081 (20130101) B01J 2219/00096 (20130101) B01J 2219/00162 (20130101) B01J 2219/1943 (20130101) B01J 2219/2486 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633255 | Campbell et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Patrick G. Campbell (Oakland, California); Theodore F. Baumann (Discovery Bay, California); Juergen Biener (San Leandro, California); Matthew Merrill (Dublin, California); Elizabeth Montalvo (Oakland, California); Marcus Worsley (Hayward, California); Monika M. Biener (San Leandro, California); Maira Raquel Ceron Hernandez (Livermore, California) |
ABSTRACT | Disclosed here is a method for producing a graphene macro-assembly (GMA)-fullerene composite, comprising providing a GMA comprising a three-dimensional network of graphene sheets crosslinked by covalent carbon bonds, and incorporating at least 20 wt. % of at least one fullerene compound into the GMA based on the initial weight of the GMA to obtain a GMA-fullerene composite. Also described are a GMA-fullerene composite produced, an electrode comprising the GMA-fullerene composite, and a supercapacitor comprising the electrode and optionally an organic or ionic liquid electrolyte in contact with the electrode. |
FILED | Monday, November 06, 2017 |
APPL NO | 15/805010 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/156 (20170801) C01B 32/194 (20170801) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) H01G 11/36 (20130101) H01G 11/38 (20130101) H01G 11/68 (20130101) H01G 11/70 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/364 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/738 (20130101) Y10S 977/896 (20130101) Y10S 977/948 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633332 | Custelcean et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Radu Custelcean (Beavercreek, Ohio); Charles A. Seipp (Beavercreek, Ohio); Neil J. Williams (Knoxville, Tennessee) |
ABSTRACT | Methods for removing oxyanions from water according to the following steps: (i) dissolving an oxyanion precipitating compound into the aqueous source to result in precipitation of an oxyanion salt of the oxyanion precipitating compound; and (ii) removing the oxyanion salt from the water containing the oxyanion to result in water substantially reduced in concentration of the oxyanion; wherein the oxyanion precipitating compound has the following composition: wherein A is a ring-containing moiety and Xm− is an anionic species with a magnitude of charge m. The invention employs bis-iminoguanidinium compounds according to Formula (1a) as well as neutral precursor compounds according to Formula (1), which can be used for removing undesirable species from aqueous solutions or air, such as removal of sulfate from water and carbon dioxide from air. |
FILED | Thursday, September 13, 2018 |
APPL NO | 16/129979 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Separation B01D 53/1425 (20130101) B01D 53/1475 (20130101) B01D 53/1493 (20130101) B01D 2252/20415 (20130101) B01D 2252/20421 (20130101) B01D 2252/20426 (20130101) B01D 2252/20431 (20130101) B01D 2252/20457 (20130101) B01D 2252/20494 (20130101) B01D 2258/06 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/5272 (20130101) C02F 2101/101 (20130101) C02F 2101/103 (20130101) C02F 2101/105 (20130101) C02F 2103/08 (20130101) Acyclic or Carbocyclic Compounds C07C 279/12 (20130101) Original (OR) Class C07C 281/18 (20130101) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 207/335 (20130101) C07D 213/00 (20130101) C07D 213/53 (20130101) C07D 239/26 (20130101) C07D 241/12 (20130101) C07D 307/52 (20130101) C07D 333/22 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/346 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633592 | Henry et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Asegun Henry (Atlanta, Georgia); Caleb Amy (Atlanta, Georgia); Malavika Bagepalli (Atlanta, Georgia); Daniel Budenstein (Atlanta, Georgia) |
ABSTRACT | An exemplary embodiment of the present invention provides a reactor system comprising: a reaction vessel comprising a reactant, a heat transfer fluid and a first reaction product, wherein the heat transfer fluid has a greater density than the first reaction product such that at least a portion of the first reaction product floats on a surface of the heat transfer fluid; a first outlet positioned at a surface level of the first reaction product, the first outlet configured to output a first outlet flow comprising at least a portion of the first reaction product and at least a portion of the heat transfer fluid; wherein the heat transfer fluid is configured to provide thermal energy to the reactant in the reaction vessel to form the first reaction product. |
FILED | Tuesday, October 31, 2017 |
APPL NO | 15/799280 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/24 (20130101) C01B 2203/1241 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 49/14 (20130101) Original (OR) Class Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/57 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/39 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633668 | Kaeppler et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Shawn Kaeppler (Oregon, Wisconsin); Natalia de Leon Gatti (Middleton, Wisconsin); Jillian Foerster (Madison, Wisconsin) |
ABSTRACT | The present invention relates to compositions and methods for modulating the juvenile to adult developmental growth transition in plants, such as grasses (e.g. maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G362718, GRMZM2G096016, or homologs thereof. Modulation of expression of one or more additional genes which affect juvenile to adult developmental growth transition such as Glossy15 or Cg1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G362718 and/or GRMZM2G096016 are also contemplated, as are transgenic plants and products produced there from, that demonstrate altered, such as extended juvenile growth, and display associated phenotypes such as enhanced yield, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production. |
FILED | Friday, April 07, 2017 |
APPL NO | 15/482588 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8261 (20130101) C12N 15/8266 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633722 | Braydich et al. |
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FUNDED BY |
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APPLICANT(S) | GDC Industries, LLC (Dayton, Ohio) |
ASSIGNEE(S) | GDC Industries, LLC (Dayton, Ohio) |
INVENTOR(S) | Michael Dennis Braydich (Beavercreek, Ohio); Harry Couch (Beavercreek, Ohio); Louis A. Luedtke (Centerville, Ohio) |
ABSTRACT | There are provided methods and systems for creating multi-phase covetics. For example, there is provided a process for making a composite material. The process includes forming a multi-phase covetic. The forming includes heating a melt including a metal in a molten state and a carbon source to a first temperature threshold to form metal-carbon bonds. The forming further includes subsequently heating the melt to a second temperature threshold, the second temperature threshold being greater than the first temperature threshold. The second temperature threshold is a temperature at or above which ordered multi-phase covetics form in the melt. |
FILED | Monday, September 10, 2018 |
APPL NO | 16/126111 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 1/02 (20130101) C22C 1/026 (20130101) Original (OR) Class C22C 1/1036 (20130101) C22C 21/00 (20130101) C22C 26/00 (20130101) C22C 2026/001 (20130101) C22C 2026/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633723 | Braydich et al. |
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FUNDED BY |
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APPLICANT(S) | GDC Industries, LLC (Dayton, Ohio) |
ASSIGNEE(S) | GDC Industries, LLC (Dayton, Ohio) |
INVENTOR(S) | Michael Dennis Braydich (Beavercreek, Ohio); Harry Couch (Beavercreek, Ohio); Louis A. Luedtke (Centerville, Ohio) |
ABSTRACT | There are provided methods and systems for creating multi-phase covetics. For example, there is provided a process for making a composite material. The process includes forming a multi-phase covetic. The forming includes heating a melt including a metal in a molten state and a carbon source to a first temperature threshold to form metal-carbon bonds. The forming further includes subsequently heating the melt to a second temperature threshold, the second temperature threshold being greater than the first temperature threshold. The second temperature threshold is a temperature at or above which ordered multi-phase covetics form in the melt. |
FILED | Monday, September 10, 2018 |
APPL NO | 16/126166 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 1/02 (20130101) C22C 1/026 (20130101) Original (OR) Class C22C 1/1036 (20130101) C22C 21/00 (20130101) C22C 26/00 (20130101) C22C 2026/001 (20130101) C22C 2026/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633750 | Tessonnier et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa States University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Jean-Philippe Tessonnier (Ames, Iowa); John Edward Matthiesen (Ames, Iowa); Nacu B. Hernandez-Cantu (Ames, Iowa); Eric W. Cochran (Ames, Iowa) |
ABSTRACT | Various embodiments disclosed relate to electrocatalytic hydrogenation of muconic acid and polymers formed from the reaction products thereof. In various embodiments, the present invention provides an electrocatalytic method to prepare 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a combination thereof, from muconic acid. The method includes passing current through a catalytic cathode in a reactor including an aqueous acidic solution including muconic acid, a supporting electrolyte, and an anode, so as to generate atomic hydrogen on the cathode surface in an amount effective to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. Also disclosed is the polymerization of 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, or a combination thereof with another compound, such as a diamine or a dialcohol, to form a polymer, such as a polyamide or a polyester. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 15/524888 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/16 (20130101) C08G 69/26 (20130101) C08G 69/28 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633985 | Garcia-Crespo et al. |
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FUNDED BY |
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APPLICANT(S) | Andrés Jose Garcia-Crespo (Greenville, South Carolina); Patrick Daniel Noble (Greenville, South Carolina) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Andrés Jose Garcia-Crespo (Greenville, South Carolina); Patrick Daniel Noble (Greenville, South Carolina) |
ABSTRACT | A system includes a blade segment having a blade and a mounting segment coupled to the blade. Additionally, the mounting segment includes a first contact face and a second contact face, wherein the first and second contact face are concave with respect to a longitudinal axis of the blade segment. To reduce stresses within the mounting segment, the mounting segment further includes a lower face coupling the first contact face and the second contact face, wherein the lower face is convex across the longitudinal axis of the blade segment. |
FILED | Monday, June 25, 2012 |
APPL NO | 13/532713 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/30 (20130101) F01D 5/284 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/71 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634012 | Tricaud et al. |
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FUNDED BY |
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APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
ASSIGNEE(S) | Cummins Inc. (Columbus, Indiana) |
INVENTOR(S) | Christophe Tricaud (Columbus, Indiana); James A. Zigan (Versailles, Indiana) |
ABSTRACT | An apparatus includes a pump circuit structured to receive pump data indicative of an operating characteristic of a pump feeding a fluid to a waste heat recovery (WHR) system; a flow circuit structured to receive valve position data indicative of a position of a valve downstream of the pump, estimate a flow rate of the fluid exiting the pump, and estimate the flow rate of the fluid exiting the valve; and a pressure circuit structured to receive pressure data indicative of the pressure of the fluid exiting the valve, estimate a change in pressure of the fluid across the WHR system, and determine a pressure of the fluid in a hot section of the WHR system based on the pressure of the fluid exiting the valve and the change in the pressure of the fluid across the WHR system. |
FILED | Friday, May 10, 2019 |
APPL NO | 16/409193 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 13/02 (20130101) F01K 23/065 (20130101) Original (OR) Class F01K 27/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634398 | van Hassel et al. |
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FUNDED BY |
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APPLICANT(S) | Carrier Corporation (Palm Beach Gardens, Florida) |
ASSIGNEE(S) | CARRIER CORPORATION (Palm Beach Gardens, Florida) |
INVENTOR(S) | Bart Antonie van Hassel (Weatogue, Connecticut); Abdelrahman Elsherbini (Windsor, Connecticut); Thomas D. Radcliff (Vernon, Connecticut); Parmesh Verma (South Windsor, Connecticut) |
ABSTRACT | A heating, ventilation, air conditioning and refrigeration (HVAC/R) system includes a sorption circuit including a heat absorption heat exchanger in fluid communication with a primary fluid flow source such that a primary fluid flow from is directed therethrough. The heat absorption heat exchanger is configured to exchange thermal energy between the primary fluid flow and a secondary fluid flow. A sorption heat exchanger includes a sorbent material to adsorb or absorb the primary fluid flow, generating thermal energy. The sorption heat exchanger is configured to transfer the generated thermal energy to a tertiary fluid flow. A heat exchange circuit is in fluid communication with the sorption circuit and includes a control valves connected to both the secondary fluid flow and the tertiary fluid flow configured to selectably direct the secondary fluid flow and/or the tertiary fluid flow to a conditioning heat exchanger or an ambient heat exchanger. |
FILED | Tuesday, October 18, 2016 |
APPL NO | 16/063512 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0014 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/00 (20130101) F25B 25/02 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 30/276 (20180101) Y02A 30/277 (20180101) Y02A 30/278 (20180101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/62 (20130101) Y02B 30/64 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634445 | Klett |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | James W. Klett (Knoxville, Tennessee) |
ABSTRACT | Disclosed are several examples of suppressors for not only suppressing the blast and flash produced as a projectile is expelled from a firearm, but also reduces backpressure and heat absorbed by the suppressors during each shot. |
FILED | Wednesday, June 12, 2019 |
APPL NO | 16/438964 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/30 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634665 | Iyer et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico); Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Rashi Iyer (Los Alamos, New Mexico); Jen-Huang Huang (Los Alamos, New Mexico); Pulak Nath (Los Alamos, New Mexico); Jennifer Harris (Los Alamos, New Mexico); John P. Wikswo, Jr. (Brentwood, Tennessee) |
ABSTRACT | Disclosed herein are embodiments of a device that can be used to mimic the biochemical and physiological actions of a lung organ. Also disclosed herein are embodiments of components that are included in the device as well as methods of making and using the device. Further disclosed are platform device embodiments and various components used therein that can be used in combination with the lung organ devices disclosed herein. In some embodiments, the disclosed devices can be used to determine drug toxicity and also can be used with one or more disease models to determine methods of treating disease. |
FILED | Thursday, September 24, 2015 |
APPL NO | 15/513949 |
ART UNIT | 1799 — Printing/Measuring and Testing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2200/027 (20130101) B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2300/0887 (20130101) B01L 2400/0481 (20130101) B01L 2400/0633 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 5/067 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5014 (20130101) G01N 33/5064 (20130101) Original (OR) Class G01N 33/5082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634732 | Warmack et al. |
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FUNDED BY |
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APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Robert J. Warmack (Oak Ridge, Tennessee); Milton Nance Ericson (Oak Ridge, Tennessee); Roger A. Kisner (Oak Ridge, Tennessee); Yarom Polsky (Oak Ridge, Tennessee) |
ABSTRACT | A system and method verifies continuity with and measures voltage across a circuit under test (in some instances simultaneously) using two or more test probes. Two or more probe continuity circuits measure continuity through the test probes by injecting a test current through and measuring a processed test current received at each of the plurality of test probes. The probe continuity circuits measure the respective processed test current rendered by the test current flowing through the test circuit at each test probe. A voltmeter measures the potential difference across the test probes. |
FILED | Friday, August 11, 2017 |
APPL NO | 15/675456 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/073 (20130101) G01R 1/06722 (20130101) G01R 31/50 (20200101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635403 | Pooser et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Raphael C. Pooser (Knoxville, Tennessee); Benjamin J. Lawrie (Oak Ridge, Tennessee); Bing Qi (Knoxville, Tennessee); Brian P. Williams (Knoxville, Tennessee) |
ABSTRACT | A system and method are provided to yield a QRNG based on homodyne detection of quantum noise (e.g., vacuum noise measured as shot noise) generated from a local oscillator, such as an LED. In one embodiment, a QRNG may be provided that is adjustable based on a control input to produce a random output that can be translated to one or more random data bits. |
FILED | Wednesday, September 26, 2018 |
APPL NO | 16/142984 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0425 (20130101) Electric Digital Data Processing G06F 7/58 (20130101) G06F 7/588 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635588 | Eckert et al. |
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FUNDED BY |
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APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
INVENTOR(S) | Yasuko Eckert (Bellevue, Washington); Maurice B. Steinman (Boxborough, Massachusetts); Steven Raasch (Boxborough, Massachusetts) |
ABSTRACT | A processing system includes a first set of one or more processing units including a first processing unit, a second set of one or more processing units including a second processing unit, and a memory having an address space shared by the first and second sets. The processing system further includes a distributed coherence directory subsystem having a first coherence directory to support a first subset of one or more address regions of the address space and a second coherence directory to support a second subset of one or more address regions of the address space. In some implementations, the first coherence directory is implemented in the system so as to have a lower access latency for the first set, whereas the second coherence directory is implemented in the system so as to have a lower access latency for the second set. |
FILED | Tuesday, June 05, 2018 |
APPL NO | 16/000199 |
ART UNIT | 2139 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 12/084 (20130101) G06F 12/0824 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635985 | Gauthier et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); INTERA Incorporated (Austin, Texas) |
INVENTOR(S) | John H. Gauthier (Albuquerque, New Mexico); Nadine E. Miner (Albuquerque, New Mexico); Michael L. Wilson (Albuquerque, New Mexico); Dennis E. Longsine (Leander, Texas) |
ABSTRACT | Methods, systems and computer program products to measure system re-taskability are disclosed. The methods, systems and computer program products may be used in the design of a new or redesign of an existing System of Systems (SoS). Systems re-tasking (aka substitutability or stand-in redundancy) is the process of using different systems to substitute for non-operational systems to meet required functionality, or using multi-function systems to fulfill higher-priority tasks. This ability can increase the overall operational availability of the SoS; it can also increase the adaptability and resilience of the SoS to unknown or changing conditions. The disclosed methods, systems and computer products include simulating an SoS over time, replacing systems that become non-operational (or damaged) with systems that can fulfill the same capability in order to maximize the SoS availability. |
FILED | Wednesday, October 22, 2014 |
APPL NO | 14/521285 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) Original (OR) Class G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0637 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636533 | Lordi et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Vincenzo Lordi (Livermore, California); Patrice Erne A. Turchi (Menlo Park, California) |
ABSTRACT | In one embodiment, an alloy includes: Zr; Fe; Cu; Ta in an amount from about 1 wt % to about 3 wt %; and one or more optional constituents selected from: Ti, Be, and Nb; and wherein the alloy comprises a ductile phase and a nanoprecipitate hard phase. According to another embodiment, a method of forming an inert matrix nuclear fuel includes: packing a hollow structure with fuel pellets and alloy precursor pellets; heating the fuel pellets and the alloy precursor pellets to at least a melting temperature of an alloy to be formed by melting the alloy precursor pellets; and solidifying the alloy into a matrix surrounding the fuel pellets. The alloy precursor pellets independently comprise: Zr; Fe; Cu; Ta present in an amount from about 1 to about 3 wt %; and one or more optional alloy constituents selected from: Ti, Be, and Nb. |
FILED | Thursday, November 10, 2016 |
APPL NO | 15/348885 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Alloys C22C 16/00 (20130101) Nuclear Reactors G21C 3/20 (20130101) G21C 3/28 (20130101) G21C 3/60 (20130101) G21C 21/02 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636632 | Hilt et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Florian Hilt (San Jose, California); Michael Q. Hovish (Mountain View, California); Nicholas Rolston (Stanford, California); Reinhold H. Dauskardt (Menlo Park, California) |
ABSTRACT | Improved deposition of optoelectronically active perovskite materials is provided with a two step process. In the first step, precursors are deposited on a substrate. In the second step, the deposited precursors are exposed to an atmospheric pressure plasma which efficiently cures the precursors to provide the desired perovskite thin film. The resulting films can have excellent optical properties combined with superior mechanical properties. |
FILED | Thursday, January 18, 2018 |
APPL NO | 15/874527 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32055 (20130101) H01J 37/32073 (20130101) H01J 37/32192 (20130101) H01J 37/32348 (20130101) H01J 37/32825 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/186 (20130101) H01L 31/1872 (20130101) H01L 33/0095 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636920 | Spagnola et al. |
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FUNDED BY |
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APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota) |
ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
INVENTOR(S) | Joseph C. Spagnola (Woodbury, Minnesota); Mark A. Roehrig (Stillwater, Minnesota); Thomas P. Klun (Lakeland, Minnesota); Alan K. Nachtigal (Minneapolis, Minnesota); Jennifer K. Schnobrich (St. Paul, Minnesota); Guy D. Joly (Shoreview, Minnesota) |
ABSTRACT | A barrier film that includes a substrate, a first polymer layer on a major surface of the substrate, an oxide layer on the first polymer layer, and a second polymer layer on the oxide layer. At least one of the first or second polymer layers includes a siloxane reaction product of a secondary or tertiary amino-functional silane having at least two silane groups. A method of making the barrier film and articles and a barrier assembly including the barrier film are also disclosed. |
FILED | Thursday, August 08, 2013 |
APPL NO | 14/420060 |
ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 7/04 (20130101) B05D 7/56 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 27/08 (20130101) B32B 27/30 (20130101) B32B 27/36 (20130101) B32B 27/281 (20130101) B32B 27/283 (20130101) B32B 27/286 (20130101) B32B 27/288 (20130101) B32B 27/308 (20130101) B32B 33/00 (20130101) B32B 2307/554 (20130101) B32B 2307/558 (20130101) B32B 2307/584 (20130101) B32B 2307/712 (20130101) B32B 2307/7244 (20130101) B32B 2307/7246 (20130101) B32B 2307/7248 (20130101) B32B 2457/00 (20130101) B32B 2457/12 (20130101) B32B 2457/20 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/045 (20130101) C08J 2367/02 (20130101) C08J 2433/14 (20130101) C08J 2483/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/04 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/133305 (20130101) G02F 2001/133337 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02167 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/31544 (20150401) Y10T 428/31547 (20150401) Y10T 428/31663 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636974 | Campos et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); BROOKHAVEN SCIENCE ASSOCIATES, LLC. (Upton, New York) |
INVENTOR(S) | Luis Miguel Campos (Brooklyn, New York); Matthew Y. Sfeir (Bethpage, New York); Jianlong Xia (New York, New York); Erik Michael Allan Busby (Patchogue, New York); Jonathan Zhaozhi Low (New York, New York) |
ABSTRACT | Embodiments of the present invention provides compounds, compositions, and methods for their preparation that provide efficient intramolecular fission, such that local order and strong nearest neighbor coupling is no longer a design constraint. Inventive materials include organic oligomers and polymers designed to exhibit strong intrachain donor-acceptor interactions and provide intramolecular singlet fission, whereby triplet populations can be generated in very high yields of, e.g., 170% or more. The inventive disclosure is directed to polymers of the general formula: [SA-SD]n with a strong electron acceptor (SA), a strong electron donor (SD), and n a positive integer equal to or greater than two; methods for their preparation and monomers used therein, blends, mixtures and formulations containing them; the use of the polymers, blends, mixtures and formulations as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations. |
FILED | Monday, October 24, 2016 |
APPL NO | 15/333043 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) C08G 2261/18 (20130101) C08G 2261/91 (20130101) C08G 2261/124 (20130101) C08G 2261/228 (20130101) C08G 2261/334 (20130101) C08G 2261/344 (20130101) C08G 2261/414 (20130101) C08G 2261/514 (20130101) C08G 2261/1412 (20130101) C08G 2261/1424 (20130101) C08G 2261/3223 (20130101) C08G 2261/3243 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0036 (20130101) Original (OR) Class H01L 51/42 (20130101) H01L 51/0043 (20130101) H01L 51/0558 (20130101) H01L 51/4253 (20130101) H01L 51/5012 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637011 | Pozin et al. |
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FUNDED BY |
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APPLICANT(S) | DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware); NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware) |
INVENTOR(S) | Michael Pozin (Brookfield, Connecticut); Walter Fred Paxton (Albuquerque, New Mexico) |
ABSTRACT | A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state. |
FILED | Tuesday, August 15, 2017 |
APPL NO | 15/677921 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/028 (20130101) H01M 2/30 (20130101) H01M 2/34 (20130101) H01M 2/0222 (20130101) H01M 2/0267 (20130101) H01M 2/0287 (20130101) Original (OR) Class H01M 2/0292 (20130101) H01M 10/0427 (20130101) H01M 2200/00 (20130101) H01M 2220/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637022 | Lampe-Onnerud et al. |
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FUNDED BY |
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APPLICANT(S) | Cadenza Innovation, Inc. (Wilton, Connecticut) |
ASSIGNEE(S) | Cadenza Innovation, Inc. (Wilton, Connecticut) |
INVENTOR(S) | Maria Christina Lampe-Onnerud (Wilton, Connecticut); Tord Per Jens Onnerud (Wilton, Connecticut); Jay Jie Shi (Acton, Massachusetts); Michael Suba (Sandy Hook, Connecticut); Joshua Liposky (Seymour, Connecticut) |
ABSTRACT | A multi-core lithium ion battery includes a sealed enclosure and a support member disposed within the sealed enclosure. The sealed enclosure may further include at least two support members housed within individual compartments, separated by shared wall(s). The support member(s) includes a plurality of cavities and a plurality of lithium ion core members which are disposed within the plurality of cavities. The battery may further include a plurality of cavity liners, each of which is positioned between a corresponding one of the lithium ion core members and a surface of a corresponding one of the cavities. The hermetically sealed enclosure may be formed using a clamshell configuration. Structures may be included in proximity to or in contact with the lithium ion core members to control gas/fluid flow therefrom. |
FILED | Wednesday, December 13, 2017 |
APPL NO | 15/840162 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/34 (20130101) H01M 2/0242 (20130101) H01M 2/347 (20130101) H01M 2/1016 (20130101) H01M 2/1027 (20130101) H01M 2/1077 (20130101) Original (OR) Class H01M 2/1094 (20130101) H01M 2/1686 (20130101) H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 16/00 (20130101) H01M 2010/4271 (20130101) H01M 2200/00 (20130101) H01M 2200/103 (20130101) H01M 2220/10 (20130101) H01M 2220/20 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637072 | Stamenkovic et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Vojislav Stamenkovic (Naperville, Illinois); Gregory K. Krumdick (Homer Glen, Illinois); Rongyue Wang (Naperville, Illinois); Nenad Markovic (Hinsdale, Illinois); Krzysztof Pupek (Plainfield, Illinois); Trevor L. Dzwiniel (Carol Stream, Illinois) |
ABSTRACT | A method for synthesis of PtNi nanocages by synthesizing Pt1Ni6 nanoparticles and acid leaching to form PtNi nanocages. The acid leaching removes nickel selectively from the core of the nanoparticle. |
FILED | Tuesday, June 12, 2018 |
APPL NO | 16/006671 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) Original (OR) Class H01M 4/9091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637099 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Lu Zhang (Lisle, Illinois); Jingjing Zhang (Willowbrook, Illinois); Ilya A. Shkrob (Chicago, Illinois); Zhengcheng Zhang (Naperville, Illinois) |
ABSTRACT | An electrolyte for a lithium-ion electrochemical cell comprises a non-aqueous solution of a lithium salt and a redox shuttle compound, wherein the redox shuttle compound comprises —OR groups at carbons 1 and 4 of a benzene ring; a first hydrocarbon ring fused to carbons 2 and 3 of the benzene ring; and a second hydrocarbon ring fused to the carbons 5 and 6 of the benzene ring, wherein either (i) the first and second hydrocarbon rings together with the benzene ring constitute two fused benzobicyclo[2.2.2]octane ring systems sharing a common benzo core group; or (ii) the first and second hydrocarbon rings together with the benzene ring constitute two fused benzobicyclo[2.2.1]heptane ring systems sharing a common benzo core group. |
FILED | Wednesday, May 17, 2017 |
APPL NO | 15/597381 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 2300/0025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637100 | Armstrong et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Beth L. Armstrong (Oak Ridge, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Sergiy Kalnaus (Knoxville, Tennessee); Hsin Wang (Knoxville, Tennessee); Katie L. Browning (Oak Ridge, Tennessee); Kevin M. Cooley (Knoxville, Tennessee) |
ABSTRACT | A method of making a passively impact resistant composite electrolyte and separator layer includes providing a suspension composition including electrically non-conducting particles that enable shear thickening. The particles can have a polydispersity index of no greater than 0.1, an average particle size in a range of from 50 nm to 1 um, and an absolute zeta potential of greater than ±40 mV. A particle suspension solvent is provided for suspending the particles. The suspension composition is applied to a porous separator material. A portion of the particles and suspension solvent penetrate the pores and the remainder of the particles in the suspension composition are distributed across the surface of the separator material. The suspension solvent is evaporated from the separator material to provide a shear thickening particle loaded separator. A separator assembly and a passivated battery are also disclosed. |
FILED | Friday, April 20, 2018 |
APPL NO | 15/958446 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/88 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0028 (20130101) H01M 2300/0085 (20130101) H01M 2300/0094 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637293 | Costinett et al. |
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FUNDED BY |
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APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Daniel Jes Costinett (Knoxville, Tennessee); Chongwen Zhao (Knoxville, Tennessee) |
ABSTRACT | A transmitter for wireless power transfer is provided. The transmitter includes an input port, a first transmission port, a second transmission port, an inverter, and a controller. An input of the inverter is coupled to the input port, and an output of the inverter is coupled in parallel to the first and second transmission ports. The controller is programmed to control the inverter to modulate an output voltage at the output of the inverter such that power from the input port is transmitted at a first frequency through the first transmission port and at a second frequency through the second transmission port. |
FILED | Thursday, September 28, 2017 |
APPL NO | 15/718767 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/12 (20160201) Original (OR) Class H02J 50/40 (20160201) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33561 (20130101) H02M 7/53871 (20130101) H02M 2007/4815 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/1441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637744 | Carroll et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Thomas E. Carroll (Richland, Washington); Satish Chikkagoudar (Richland, Washington); Kristine M. Arthur-Durett (Richland, Washington); Dennis G. Thomas (Kennewick, Washington) |
ABSTRACT | A network analysis tool evaluates network flow information in complementary workflows to identify one-hop behavior of network assets and also identify multi-hop dependencies between network assets. In one workflow (e.g., using association rule learning), the network analysis tool can identify significant one-hop communication patterns to and/or from network assets, taken individually. Based on the identified one-hop behavior, the network analysis tool can discover patterns of similar communication among different network assets, which can inform decisions about deploying patch sets, mitigating damage, configuring a system, or detecting anomalous behavior. In a different workflow (e.g., using deep learning or cross-correlation analysis), the network analysis tool can identify significant multi-hop communication patterns that involve network assets in combination. Based on the identified multi-hop dependencies, the network analysis tool can discover functional relationships between network assets, which can inform decisions about configuring a system, managing critical network assets, or protecting critical network assets. |
FILED | Wednesday, April 12, 2017 |
APPL NO | 15/486162 |
ART UNIT | 2445 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/14 (20130101) H04L 41/16 (20130101) Original (OR) Class H04L 43/026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637785 | Lyle et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Joshua A. Lyle (Chicago, Illinois); Nathaniel Evans (Orland Hills, Illinois) |
ABSTRACT | Systems, methods, and storage media for utilizing software defined networking for a multiple operating system rotational environment, executing on a computing device are disclosed. Some implementations may: receive a request from a user device; modify a packet of the request with a destination address and a port of a first server; forward the modified packet of the request to a controller server; receive a flow modification from the controller server based on the modified packet; and modify further received packets from the user device based on the received flow modification. |
FILED | Thursday, August 16, 2018 |
APPL NO | 15/998485 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/38 (20130101) H04L 45/64 (20130101) H04L 47/2458 (20130101) H04L 47/2466 (20130101) Original (OR) Class H04L 47/2483 (20130101) H04L 49/254 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE47965 | Liszkai et al. |
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FUNDED BY |
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APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
ASSIGNEE(S) | NUSCALE POWER LLC (Portland, Oregon) |
INVENTOR(S) | Tamas Liszkai (Corvallis, Oregon); Seth Cadell (Corvallis, Oregon) |
ABSTRACT | A system for attenuating seismic forces includes a reactor pressure vessel containing nuclear fuel and a containment vessel that houses the reactor pressure vessel. Both the reactor pressure vessel and the containment vessel include a bottom head. Additionally, the system includes a base support to contact a support surface on which the containment vessel is positioned in a substantially vertical orientation. An attenuation device is located between the bottom head of the reactor pressure vessel and the bottom head of the containment vessel. Seismic forces that travel from the base support to the reactor pressure vessel via the containment vessel are attenuated by the attenuation device in a direction that is substantially lateral to the vertical orientation of the containment vessel. |
FILED | Tuesday, April 24, 2018 |
APPL NO | 15/961804 |
ART UNIT | 3993 — Central Reexamination Unit (Mechanical) |
CURRENT CPC | Nuclear Reactors G21C 1/322 (20130101) G21C 5/10 (20130101) G21C 9/04 (20130101) Original (OR) Class G21C 13/024 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 10631475 | Goldberg et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ken Goldberg (Mill Valley, California); Stefano Carpin (Santa Cruz, California); Stephen McKinley (Berkeley, California); Stavros Vougioukas (Davis, California); David Gealy (Arroyo Grande, California) |
ABSTRACT | According to some embodiments of the invention, an adjusting device for adjusting a passive drip irrigation valve to enable precision irrigation includes a device body configured to be at least one of hand-held or attachable to a robot, the device body having a manipulator end, and a manipulator assembly contained within and extending from the manipulator end of the device body. The manipulator assembly includes a coarse alignment adjustment assembly constructed and arranged to align the adjusting device with the passive drip irrigation valve. The manipulator assembly also includes a fine actuator configured to rotate the passive drip irrigation valve by a specified angle. |
FILED | Thursday, August 11, 2016 |
APPL NO | 15/752474 |
ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 25/02 (20130101) A01G 25/16 (20130101) Original (OR) Class Manipulators; Chambers Provided With Manipulation Devices B25J 5/007 (20130101) B25J 11/00 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 47/045 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/106 (20130101) G05B 2219/2625 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/028 (20130101) G05D 1/0246 (20130101) G05D 1/0282 (20130101) G05D 2201/0201 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10415 (20130101) Technologies for Adaptation to Climate Change Y02A 40/237 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632206 | Emrick et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Todd Emrick (South Deerfield, Massachusetts); Xiangji Chen (Woodbury, Minnesota); Samantha Page (Goleta, California) |
ABSTRACT | The invention generally relates to zwitterionic polymers (including zwitterionic copolymers), such as polymethacrylic structures, with pendent functional moieties, such as therapeutic or biologic moieties. More particularly, the invention relates to phosphorylcholine-substituted methacrylic polymers prepared by free radical polymerization and click chemistry, for example, and compositions and products comprising same, as well as related methods and uses of the compositions, for example, as biological or therapeutic agents and in drug delivery thereof. |
FILED | Thursday, June 30, 2016 |
APPL NO | 15/198372 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 47/58 (20170801) A61K 47/48176 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 220/10 (20130101) C08F 220/34 (20130101) C08F 230/02 (20130101) C08F 238/00 (20130101) C08F 293/005 (20130101) C08F 2438/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10632585 | Greenslet |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Hitomi Greenslet (Gainesville, Florida) |
ABSTRACT | Various examples are provided for hybrid tools including fixed-abrasive and loose-abrasive phases. In one example, a hybrid tool for finishing an internal surface of a workpiece includes a metallic rod and magnetic abrasive bonded to one or more defined portions of the metallic rod by an adhesive that dissolves when n contact with a lubricant used to finish the internal surface of the workpiece. In another example, a method for finishing an internal surface of a workpiece includes mounting the workpiece in a chuck of a lathe; positioning a hybrid tool inside an internal cavity of the workpiece using one or more pole-tips; providing an amount of the lubricant to the internal cavity; and rotating the workpiece with the lathe while controlling positioning of the hybrid tool inside the internal cavity using the one or more pole-types. |
FILED | Friday, April 22, 2016 |
APPL NO | 15/568494 |
ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 1/005 (20130101) Original (OR) Class B24B 5/40 (20130101) B24B 31/006 (20130101) B24B 31/112 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633493 | Scott et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Evan A. Scott (Chicago, Illinois); Sean D. Allen (Chicago, Illinois) |
ABSTRACT | Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers. |
FILED | Friday, July 21, 2017 |
APPL NO | 15/656905 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/107 (20130101) A61K 9/1273 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/436 (20130101) A61K 38/465 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 49/0047 (20130101) A61K 49/0054 (20130101) A61K 49/0065 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0861 (20130101) B01F 5/02 (20130101) B01F 5/0256 (20130101) B01F 13/0059 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/14 (20130101) Original (OR) Class C08J 2371/02 (20130101) C08J 2381/02 (20130101) C08J 2381/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Enzymes C12Y 301/03001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633556 | Tiwari et al. |
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FUNDED BY |
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APPLICANT(S) | FLORA COATINGS LLC (, None) |
ASSIGNEE(S) | FLORA COATINGS LLC (PH, Arizona) |
INVENTOR(S) | Atul Tiwari (Phoenix, Arizona); Anupama Chaturvedi (Phoenix, Arizona) |
ABSTRACT | A liquid silicone-based composition for forming a coating, the composition comprising a silazane, an organometallic compound, an alkoxysilane, and an aprotic solvent, wherein when applied to a substrate the liquid composition cures to form a quasi-ceramic coating under ambient conditions. |
FILED | Thursday, December 28, 2017 |
APPL NO | 15/857568 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/58 (20130101) C08G 79/00 (20130101) C08G 79/10 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/34 (20130101) C08K 3/36 (20130101) C08K 5/057 (20130101) C08K 5/5415 (20130101) C08K 2003/2227 (20130101) C08K 2201/011 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/14 (20130101) C09D 183/16 (20130101) C09D 183/16 (20130101) C09D 185/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633628 | Yeh et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel H. Yeh (Tampa, Florida); Ivy Lea Cormier Drexler (St. Petersburg, Florida); Melanie Pickett (Tampa, Florida); David Fulcher (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Daniel H. Yeh (Tampa, Florida); Ivy Lea Cormier Drexler (St. Petersburg, Florida); Melanie Pickett (Tampa, Florida); David Fulcher (Tampa, Florida) |
ABSTRACT | In one embodiment, an algae cultivation system includes a photobioreactor adapted for immersion in growth media contained within the growth media reactor, the photobioreactor including a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, a porous membrane filter incorporated into one of the panels that enables water, carbon dioxide, and nutrients contained within the growth media to pass into the interior space but prevents contaminants contained within the growth media from passing into the interior space, and a gas control valve incorporated into one of the panels that when open enables photosynthetic gas produced by algae growth within the container to escape but when closed prevents the photosynthetic gas from escaping so as to build pressure within the container that forces water out from the container and dewaters the algae. |
FILED | Monday, November 14, 2016 |
APPL NO | 15/350582 |
ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/22 (20130101) C12M 29/04 (20130101) C12M 29/20 (20130101) C12M 41/48 (20130101) C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633648 | Seelig et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Georg Seelig (Seattle, Washington); Anna Kuchina (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
ABSTRACT | Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers. |
FILED | Friday, February 10, 2017 |
APPL NO | 15/430108 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class C12N 15/1065 (20130101) C12N 15/1065 (20130101) C12N 15/1068 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2525/191 (20130101) C12Q 2563/103 (20130101) C12Q 2563/179 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633672 | Ozias-Akins et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
INVENTOR(S) | Peggy Ozias-Akins (Tifton, Georgia); Joann A. Conner (Tifton, Georgia) |
ABSTRACT | Methods and compositions disclosed herein generally relate to genes involved in plant reproduction and methods of using the same. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 15/031019 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8287 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633676 | Gonzalez et al. |
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FUNDED BY |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Ramon Gonzalez (Houston, Texas); James Clomburg (Houston, Texas); Clementina Dellomonaco (Wilmington, Delaware); Elliot N. Miller (Houston, Texas) |
ABSTRACT | The invention relates to recombinant microorganisms that have been engineered to produce various chemicals using genes that have been repurposed to create a reverse beta oxidation pathway. Generally speaking, the beta oxidation cycle is expressed and driven in reverse by modifying various regulation points for as many cycles as needed, and then the CoA thioester intermediates are converted to useful products by the action of termination enzymes. |
FILED | Monday, August 15, 2016 |
APPL NO | 15/237190 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/02 (20130101) C12P 5/026 (20130101) C12P 7/04 (20130101) C12P 7/16 (20130101) Original (OR) Class C12P 7/40 (20130101) C12P 7/42 (20130101) C12P 7/6409 (20130101) Enzymes C12Y 101/01035 (20130101) C12Y 102/0105 (20130101) C12Y 103/99003 (20130101) C12Y 203/01 (20130101) C12Y 402/01017 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633700 | Ju et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York) |
ABSTRACT | This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. |
FILED | Monday, November 26, 2018 |
APPL NO | 16/200564 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633701 | Weitz et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Jeremy Agresti (Richmond, California); Michael P. Weiner (Guilford, Connecticut); Adam R. Abate (Daly City, California); Tony Hung (Peachtree City, Georgia) |
ABSTRACT | The present invention relates to systems and methods for sequencing nucleic acids, including sequencing nucleic acids in fluidic droplets. In one set of embodiments, the method employs sequencing by hybridization using droplets such as microfluidic droplets. In some embodiments, droplets are formed which include a target nucleic acid, a nucleic acid probe, and at least one identification element, such as a fluorescent particle. The nucleic acid probes that hybridize to the target nucleic acid are determined, in some instances, by determining the at least one identification element. The nucleic acid probes that hybridize to the target nucleic acid may be used to determine the sequence of the target nucleic acid. In certain instances, the microfluidic droplets are provided with reagents that modify the nucleic acid probe. In some cases, a droplet, such as those described above, is deformed such that the components of the droplets individually pass a target area. |
FILED | Monday, August 07, 2017 |
APPL NO | 15/670885 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2537/143 (20130101) C12Q 2563/149 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633750 | Tessonnier et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa States University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Jean-Philippe Tessonnier (Ames, Iowa); John Edward Matthiesen (Ames, Iowa); Nacu B. Hernandez-Cantu (Ames, Iowa); Eric W. Cochran (Ames, Iowa) |
ABSTRACT | Various embodiments disclosed relate to electrocatalytic hydrogenation of muconic acid and polymers formed from the reaction products thereof. In various embodiments, the present invention provides an electrocatalytic method to prepare 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a combination thereof, from muconic acid. The method includes passing current through a catalytic cathode in a reactor including an aqueous acidic solution including muconic acid, a supporting electrolyte, and an anode, so as to generate atomic hydrogen on the cathode surface in an amount effective to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. Also disclosed is the polymerization of 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, or a combination thereof with another compound, such as a diamine or a dialcohol, to form a polymer, such as a polyamide or a polyester. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 15/524888 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/16 (20130101) C08G 69/26 (20130101) C08G 69/28 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634544 | Przybyla |
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FUNDED BY |
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APPLICANT(S) | Chirp Microsystems, Inc. (Berkeley, California) |
ASSIGNEE(S) | CHIRP MICROSYSTEMS (Bereley, California) |
INVENTOR(S) | Richard J. Przybyla (Berkeley, California) |
ABSTRACT | An ultrasonic transceiver can detect the presence of nearby moving objects while rejecting signals from stationary targets and from transmitter signal feedthrough. Data corresponding to received ultrasound signals are stored in a digital memory. For each sample in a measurement, a difference is calculated between corresponding samples in the stored data corresponding to received signals for current and previous measurements to estimate a time of flight to a moving object. |
FILED | Thursday, March 09, 2017 |
APPL NO | 15/454363 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/2962 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634604 | Grier et al. |
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FUNDED BY |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
INVENTOR(S) | David G. Grier (New York, New York); Fook Chiong Cheong (Singapore, Singapore); Ke Xiao (Elmhurst, New York) |
ABSTRACT | An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization. |
FILED | Monday, July 31, 2017 |
APPL NO | 15/665126 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1459 (20130101) G01N 15/1475 (20130101) Original (OR) Class G01N 15/1484 (20130101) G01N 2015/003 (20130101) G01N 2015/0065 (20130101) G01N 2015/1445 (20130101) G01N 2015/1454 (20130101) G01N 2015/1493 (20130101) G01N 2015/1497 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0056 (20130101) G02B 21/0068 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 2001/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634653 | Dasgupta et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); DIONEX CORPORATION (Sunnyvale, California) |
ASSIGNEE(S) | Dionex Corporation (Sunnyvale, California); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Purnendu K. Dasgupta (Arlington, Texas); Akinde F. Kadjo (Grand Prairie, Texas); Kannan Srinivasan (Tracy, California) |
ABSTRACT | Systems, methods and devices are taught for providing analytical methods for peak-shaped responses separated in time or space, including quantitation of chromatographic peaks based on a width measurement of a peak trace at a selected height as a quantitation element. Methods of treating a peak trace as a composition of exponential functions representing a leading and a trailing end are included. Methods that facilitate the detection of impurities in peak trace outputs are also included. |
FILED | Tuesday, November 28, 2017 |
APPL NO | 15/824962 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Separation B01D 15/161 (20130101) B01D 15/163 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/02 (20130101) G01N 30/16 (20130101) G01N 30/30 (20130101) G01N 30/86 (20130101) G01N 30/8637 (20130101) Original (OR) Class G01N 2030/025 (20130101) G01N 2030/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634820 | Shih et al. |
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FUNDED BY |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas) |
INVENTOR(S) | Wei-Chuan Shih (Houston, Texas); Yu-Lung Sung (Houston, Texas) |
ABSTRACT | A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate. |
FILED | Friday, May 11, 2018 |
APPL NO | 15/977019 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0048 (20130101) B29D 11/00365 (20130101) B29D 11/00442 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Original (OR) Class G02B 1/041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634899 | Gopinath et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
INVENTOR(S) | Juliet T. Gopinath (Boulder, Colorado); Emily A. Gibson (Boulder, Colorado); Victor M. Bright (Boulder, Colorado); Richard Weir (Longmont, Colorado); Diego Restrepo (Littleton, Colorado); Baris Ozbay (Denver, Colorado) |
ABSTRACT | The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques. |
FILED | Thursday, January 22, 2015 |
APPL NO | 15/113303 |
ART UNIT | 2486 — Recording and Compression |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/14 (20130101) G02B 6/06 (20130101) G02B 21/006 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) G02B 23/26 (20130101) G02B 23/243 (20130101) Original (OR) Class G02B 23/2446 (20130101) G02B 23/2469 (20130101) G02B 26/005 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 2005/2255 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636654 | Xia |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Fengnian Xia (Orange, Connecticut) |
ABSTRACT | A scalable approach for the synthesis of black phosphorus (BP) material thin films over large areas is described. A red phosphorus (RP) material thin film may be deposited on a substrate followed by conversion to a BP material thin film using high-pressure alone or high pressure and high temperature. A thin-film of dielectric material such as hexagonal boron nitride (hBN) can be formed on a RP material film before the conversion is performed to improve the crystalline quality and stability of the converted BP material. Surprisingly, an atomically sharp and defect-free interface can be formed between the converted BP material and hBN. The BP material has high crystalline uniformity and can be used to fabricate thin-film transistors and optoelectronic devices such as infrared photodetectors. |
FILED | Friday, April 06, 2018 |
APPL NO | 15/947202 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/006 (20130101) C01B 25/023 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02422 (20130101) H01L 21/02521 (20130101) H01L 21/02631 (20130101) Original (OR) Class H01L 21/6835 (20130101) H01L 23/3157 (20130101) H01L 29/26 (20130101) H01L 29/786 (20130101) H01L 29/78696 (20130101) H01L 2221/68304 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636731 | Bakir et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Muhannad S. Bakir (Atlanta, Georgia); Paul Kim Jo (Atlanta, Georgia) |
ABSTRACT | Disclosed are various embodiments that involve mechanically flexible interconnects, methods of making mechanically flexible interconnects, methods of using mechanically flexible interconnects, and the like. |
FILED | Thursday, July 14, 2016 |
APPL NO | 15/744302 |
ART UNIT | 2819 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/71 (20130101) H01L 21/4853 (20130101) H01L 23/49811 (20130101) Original (OR) Class H01L 24/16 (20130101) H01L 2924/01029 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636974 | Campos et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); BROOKHAVEN SCIENCE ASSOCIATES, LLC. (Upton, New York) |
INVENTOR(S) | Luis Miguel Campos (Brooklyn, New York); Matthew Y. Sfeir (Bethpage, New York); Jianlong Xia (New York, New York); Erik Michael Allan Busby (Patchogue, New York); Jonathan Zhaozhi Low (New York, New York) |
ABSTRACT | Embodiments of the present invention provides compounds, compositions, and methods for their preparation that provide efficient intramolecular fission, such that local order and strong nearest neighbor coupling is no longer a design constraint. Inventive materials include organic oligomers and polymers designed to exhibit strong intrachain donor-acceptor interactions and provide intramolecular singlet fission, whereby triplet populations can be generated in very high yields of, e.g., 170% or more. The inventive disclosure is directed to polymers of the general formula: [SA-SD]n with a strong electron acceptor (SA), a strong electron donor (SD), and n a positive integer equal to or greater than two; methods for their preparation and monomers used therein, blends, mixtures and formulations containing them; the use of the polymers, blends, mixtures and formulations as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations. |
FILED | Monday, October 24, 2016 |
APPL NO | 15/333043 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) C08G 2261/18 (20130101) C08G 2261/91 (20130101) C08G 2261/124 (20130101) C08G 2261/228 (20130101) C08G 2261/334 (20130101) C08G 2261/344 (20130101) C08G 2261/414 (20130101) C08G 2261/514 (20130101) C08G 2261/1412 (20130101) C08G 2261/1424 (20130101) C08G 2261/3223 (20130101) C08G 2261/3243 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0036 (20130101) Original (OR) Class H01L 51/42 (20130101) H01L 51/0043 (20130101) H01L 51/0558 (20130101) H01L 51/4253 (20130101) H01L 51/5012 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637293 | Costinett et al. |
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FUNDED BY |
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APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Daniel Jes Costinett (Knoxville, Tennessee); Chongwen Zhao (Knoxville, Tennessee) |
ABSTRACT | A transmitter for wireless power transfer is provided. The transmitter includes an input port, a first transmission port, a second transmission port, an inverter, and a controller. An input of the inverter is coupled to the input port, and an output of the inverter is coupled in parallel to the first and second transmission ports. The controller is programmed to control the inverter to modulate an output voltage at the output of the inverter such that power from the input port is transmitted at a first frequency through the first transmission port and at a second frequency through the second transmission port. |
FILED | Thursday, September 28, 2017 |
APPL NO | 15/718767 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/12 (20160201) Original (OR) Class H02J 50/40 (20160201) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33561 (20130101) H02M 7/53871 (20130101) H02M 2007/4815 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/1441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637391 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Kyusang Lee (Ann Arbor, Michigan); Matthew Shlian (Ann Arbor, Michigan); Chih-Wei Chien (Ann Arbor, Michigan); Peicheng Ku (Ann Arbor, Michigan); Aaron Lamoreux (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan) |
ABSTRACT | There is disclosed Kirigami-inspired structures for use in solar tracking applications. When coupled with thin-film active materials, the disclosed microstructures can track solar position and maximize solar power generation. In one embodiment, there is disclosed a photovoltaic system comprising a single-axis, or multi-axis solar tracking structure comprising a support structure made of a flexible material having a defined unit cell structure, and a flexible photovoltaic cell disposed on the support structure. There is also disclosed methods of making such structures in which the photovoltaic cell is mounted to the support structure by a direct-attachment bonding processes such as cold-welding. |
FILED | Friday, November 28, 2014 |
APPL NO | 15/034299 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/054 (20141201) H01L 31/1844 (20130101) H01L 31/03046 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/32 (20141201) Original (OR) Class H02S 30/20 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637575 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Chi Zhang (Madison, Wisconsin) |
ABSTRACT | A system for identifying the location of the mobile device uses standard fluorescent light fixtures commonly found in indoor environments and detects minor variations in the light output of those fixtures caused by normal manufacturing variation. These variations are catalogued as identifying fingerprints together with location of the light fixtures to provide for navigation. |
FILED | Wednesday, May 25, 2016 |
APPL NO | 15/164195 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/116 (20130101) Original (OR) Class H04B 10/1141 (20130101) Wireless Communication Networks H04W 4/02 (20130101) H04W 4/024 (20180201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637586 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ASSIGNEE(S) | National Science Foundation (Alexandria, Virginia) |
INVENTOR(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ABSTRACT | Systems and methods for underwater communication using a MIMO acoustic channel. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder. |
FILED | Friday, August 25, 2017 |
APPL NO | 15/686390 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03057 (20130101) H04L 27/0008 (20130101) H04L 2025/03426 (20130101) H04L 2025/03636 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 10632828 | Trase et al. |
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FUNDED BY |
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APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Larry M. Trase (Litchfield, Ohio); Ralph H. Jansen (Westlake, Ohio); Peter E. Kascak (Cleveland, Ohio) |
ABSTRACT | A prime mover is combined with a flywheel storage device and a control system to implement a flywheel pulse and glide system in a vehicle. In one embodiment, the control system is configured to cycle power delivery between the prime mover and the flywheel storage device to power the vehicle. The prime mover, when activated by the control system, is configured to power the vehicle and spin up the flywheel storage device to capture a sufficient amount of energy. |
FILED | Friday, March 29, 2013 |
APPL NO | 13/853308 |
ART UNIT | 3656 — Material and Article Handling |
CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/10 (20130101) Original (OR) Class B60K 6/30 (20130101) B60K 6/48 (20130101) B60K 6/105 (20130101) B60K 6/442 (20130101) B60K 6/485 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 2240/44 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/06 (20130101) B60W 30/18127 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633256 | Guo et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Haiquan Guo (Avon, Ohio); Frances I. Hurwitz (Shaker Heights, Ohio) |
ABSTRACT | Aerogels, aerogel composites and methods of making the same are discussed. One example method can include the act of creating a Boehmite colloid and adding a hydrolyzed silicon precursor to form a sol. A reinforcement can be infused with the sol, gelled to form a gel, then dried to form an aerogel composite. Such a method can also include the acts of performing one or more solvent exchanges and subjecting the gel composite to subcritical drying. Additionally, such a method can include the act of heat treating the aerogel composite. The aerogel composite can be used in high temperature, flexible seals capable of withstanding temperatures, pressures, and compression levels associated with aerodynamic heating generated during flight and in aerospace applications. The aerogel composite also can be used in thermal protection systems designed for fire protection for structures or in personnel fire protective equipment. |
FILED | Wednesday, April 19, 2017 |
APPL NO | 15/491168 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/157 (20130101) Original (OR) Class Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10634820 | Shih et al. |
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FUNDED BY |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas) |
INVENTOR(S) | Wei-Chuan Shih (Houston, Texas); Yu-Lung Sung (Houston, Texas) |
ABSTRACT | A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate. |
FILED | Friday, May 11, 2018 |
APPL NO | 15/977019 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0048 (20130101) B29D 11/00365 (20130101) B29D 11/00442 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Original (OR) Class G02B 1/041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635761 | English et al. |
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FUNDED BY |
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APPLICANT(S) | ENERGID TECHNOLOGIES CORPORATION (Cambridge, Massachusetts) |
ASSIGNEE(S) | Energid Technologies Corporation (Cambridge, Massachusetts) |
INVENTOR(S) | James D. English (Alva, Florida); Ryan S. Penning (Madison, Wisconsin); Douglas E. Barker (Somerville, Massachusetts); James A. Bacon (Bourbonnais, Illinois) |
ABSTRACT | A method, computer program product, and computer system for configuring a stochastic simulation scenario, wherein the stochastic simulation scenario may include one or more variables without a complete probability distribution. The stochastic simulation scenario may be executed to generate one or more results of the stochastic simulation scenario. At least a portion of the one or more variables without the probability distribution may be optimized using one or more optimization metrics on the one or more results of the stochastic simulation scenario. |
FILED | Friday, April 29, 2016 |
APPL NO | 15/142157 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/23446 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 2201/0213 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 17/5095 (20130101) G06F 2217/10 (20130101) G06F 2217/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10636323 | Buras et al. |
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FUNDED BY |
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APPLICANT(S) | TIETRONIX SOFTWARE, INC. (Houston, Texas) |
ASSIGNEE(S) | Tienovix, LLC (Houston, Texas) |
INVENTOR(S) | William R. Buras (Friendswood, Texas); Craig S. Russell (League City, Texas); Kyle Q. Nguyen (League City, Texas) |
ABSTRACT | A medical guidance system providing real-time, three-dimensional (3D) augmented reality (AR) feedback guidance to a novice user of medical equipment having limited medical training, to achieve improved diagnostic or treatment outcomes. |
FILED | Tuesday, January 23, 2018 |
APPL NO | 15/878314 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/52 (20130101) A61B 8/085 (20130101) A61B 8/466 (20130101) A61B 8/467 (20130101) A61B 8/4245 (20130101) A61B 8/4254 (20130101) A61B 8/4263 (20130101) A61B 34/20 (20160201) A61B 90/361 (20160201) A61B 2034/2048 (20160201) A61B 2034/2055 (20160201) A61B 2090/365 (20160201) A61B 2090/378 (20160201) A61B 2090/3945 (20160201) A61B 2562/0219 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/016 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/065 (20130101) G09B 23/286 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 40/63 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10637202 | Mitchell |
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FUNDED BY |
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APPLICANT(S) | Goodrich Corporation (Charlotte, North Carolina) |
ASSIGNEE(S) | Goodrich Corporation (Charlotte, North Carolina) |
INVENTOR(S) | Michael D. Mitchell (Albuquerque, New Mexico) |
ABSTRACT | A tool for demating multi-pin connectors includes a first fork including an inner fork member and an outer fork member operatively connected for relative movement parallel to a longitudinal fork axis. A second fork is spaced apart from the first fork wherein the second fork includes an inner fork member and an outer fork member operatively connected for relative movement parallel to the longitudinal fork axis. A handle connects the first fork to the second fork. The handle includes an outer handle member fixedly connecting the outer fork members of the first and second forks, and the handle includes an inner handle member fixedly connecting the inner fork members of the first and second forks. Relative movement of the inner and outer handle members causes relative movement of the inner and outer fork members of the first and second forks for demating multi-pin electrical connectors from sockets. |
FILED | Thursday, April 27, 2017 |
APPL NO | 15/499182 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 27/00 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 43/26 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 10633671 | Fellers et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Kansas State University Research Foundation (Manhattan, Kansas) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | John Fellers (Manhattan, Kansas); Harold N. Trick (Olsburg, Kansas); Luisa Cruz (Plant City, Florida); Jessica Rupp (Manhattan, Kansas) |
ABSTRACT | Disclosed is a dsRNA construct used to silencing specific eukaryotic translation initiation factor in plants to produce a plant resistant to viruses such as Potyviruses, Luteoviruses, and Furoviruses. More specifically, the plant would be resistant to viruses such as Wheat streak mosaic virus, Triticum mosaic virus, Soil bourne mosaic virus, or Barley yellow dwarf virus. Also disclosed are non-transgenic wheat plants having the genes for eIF(iso)4E-2 or eIF4G silenced. |
FILED | Friday, January 19, 2018 |
APPL NO | 15/875168 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8283 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10633672 | Ozias-Akins et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
INVENTOR(S) | Peggy Ozias-Akins (Tifton, Georgia); Joann A. Conner (Tifton, Georgia) |
ABSTRACT | Methods and compositions disclosed herein generally relate to genes involved in plant reproduction and methods of using the same. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 15/031019 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8287 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 10633248 | Ashikhmin |
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FUNDED BY |
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APPLICANT(S) | Alcatel Lucent (Boulogne-Billancourt, France) |
ASSIGNEE(S) | ALCATEL LUCENT (Nozay, France) |
INVENTOR(S) | Alexei Ashikhmin (Morristown, New Jersey) |
ABSTRACT | An apparatus includes a device having n input ports and n output ports. The n input ports are configured to receive n corresponding physical objects of a physically processed, quantum redundancy coded state. The n output ports are configured to output the n physical objects in the physically processed, quantum redundancy coded state. The device is configured to measure bits of a syndrome of the physically processed, quantum redundancy coded state by passing the n physical objects through the device. The device is configured to measure a parity check bit for the measured bits of the syndrome by the passing the n physical objects through the device. |
FILED | Monday, March 05, 2018 |
APPL NO | 15/911909 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Coding; Decoding; Code Conversion in General H03M 13/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10635971 | Chelian et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Suhas E. Chelian (San Jose, California); Matthias Ziegler (Agoura Hills, California); James Benvenuto (Beverly Hills, California); Jeffrey Lawrence Krichmar (Cardiff By the Sea, California); Randall C. O'Reilly (Boulder, Colorado); Rajan Bhattacharyya (Sherman Oaks, California) |
ABSTRACT | Described is a system for proactive and reactive cognitive control using a neural module. The system calculates, for each hypothesis of a set of hypotheses, a probability that an event will occur. The neural module comprises a plurality of neurons and includes the PC module, a prefrontal cortex (PFC) module, an anterior cingulate cortex (ACC) module, a locus coeruleus (LC) module, and a basal forebrain (BF) module. The set of hypotheses are related to tasks to be performed by a plurality of groups, each group having a corresponding hypothesis. For each probability, the system calculates a conflict value across all hypotheses with the ACC module, compares each conflict value to a predetermined threshold using the BF and LC modules. A determination is made whether to directly output the calculated probability or perform an additional probability calculation and output an updated probability. |
FILED | Tuesday, December 01, 2015 |
APPL NO | 14/955722 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 7/005 (20130101) G06N 20/00 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 10634584 | Farris et al. |
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FUNDED BY |
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APPLICANT(S) | The Mitre Corporation (McLean, Virginia) |
ASSIGNEE(S) | ROKU, INC. (Los Gatos, California) |
INVENTOR(S) | Michael Heath Farris (Vienna, Virginia); Kevin Robert Gemp (Falls Church, Virginia); David Masters (Great Falls, Virginia) |
ABSTRACT | A microscopic collection device, method for collecting a microscopic sample from a target surface, and the work stand for holding the microscopic collection device are provided. The microscopic collection device includes a holding element comprising a handle at one end and a collection platform connected to the holding element at a second end. The collection platform includes a collection surface on which the microscopic sample is deposited when the microscopic collection device comes into contact with the target surface. A tape is inserted through a slit and wrapped around the collection platform. The work stand includes a slit capable of holding the microscopic collection device such that the collection platform is perpendicular to the top surface of the work stand. A microscopic sample, collected using the microscopic collection device, is not only collected from the target surface but is also concentrated onto the collection face of the tape. Removal of the collection face of the tape excludes excess tape that would disrupt downstream analysis of the microscopic sample. |
FILED | Thursday, December 17, 2015 |
APPL NO | 14/973083 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 1/2813 (20130101) G01N 2001/028 (20130101) G01N 2001/2833 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 10633114 | Momoh |
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FUNDED BY |
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APPLICANT(S) | James Momoh (Upper Marlboro, Maryland) |
ASSIGNEE(S) | HOWARD UNIVERSITY (Washington, District of Columbia) |
INVENTOR(S) | James Momoh (Upper Marlboro, Maryland) |
ABSTRACT | An airport lighting system includes one or more lighting elements, a transient protection apparatus, and one or more electrical control cabinets. The transient protection apparatus is coupled to the one or more lighting elements. One or more electrical control cabinets are coupled to the transient protection apparatus. Each of the control cabinets produces one or more of control and power signals that are effective to operate the one or more lighting elements. The transient protection apparatus is configured to provide protection for one or more of the electrical control cabinets and the one or more lighting elements from electrical surges. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 16/060249 |
ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/20 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2111/06 (20130101) Traffic Control Systems G08G 5/025 (20130101) G08G 5/0026 (20130101) Emergency Protective Circuit Arrangements H02H 9/005 (20130101) H02H 9/041 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 37/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 10634820 | Shih et al. |
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FUNDED BY |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEMS (Houston, Texas) |
INVENTOR(S) | Wei-Chuan Shih (Houston, Texas); Yu-Lung Sung (Houston, Texas) |
ABSTRACT | A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate. |
FILED | Friday, May 11, 2018 |
APPL NO | 15/977019 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0048 (20130101) B29D 11/00365 (20130101) B29D 11/00442 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) Original (OR) Class G02B 1/041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 10633425 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | SILVER CREEK PHARMACEUTICALS, INC. (San Francisco, California) |
ASSIGNEE(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
INVENTOR(S) | Laura D. J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Los Angeles, California); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Tuesday, July 03, 2018 |
APPL NO | 16/026319 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/33 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 28, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200428.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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