FedInvent™ Patents

Patent Details for Tuesday, May 05, 2020

This page was updated on Monday, March 27, 2023 at 06:04 AM GMT

Department of Defense (DOD)

10638759 — Conjugated polyelectrolytes and methods of using the same

US 10638759	Whitten et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	David G. Whitten (Albuquerque, New Mexico); Harry Craig Pappas (Albuquerque, New Mexico); Eric H. Hill (Donostia, Spain); Kirk S. Schanze (Gainesville, Florida); Anand Parthasarathy (Gainesville, Florida); Yun Huang (Gainesville, Florida); Thomas S. Corbitt (Albuquerque, New Mexico)
ABSTRACT	Various embodiments disclosed relate to conjugated polyelectrolytes and methods of using the same. Various embodiments provide a conjugated polyelectrolyte including a subunit having the structure —R¹—Y—R²—Z—. At each occurrence, R¹is independently chosen from 1,4-bonded phenylene substituted by —X—R³-R⁴j times and 2,5-bonded thiophene substituted by —X—R³-R⁴j times. At each occurrence, Y is independently chosen from a bond and —C≡C—. At each occurrence, R²is independently chosen from a bond, a substituted or unsubstituted phenylene, thiophenylene, azulenylene, heptalenylene, biphenylene, indacenylene, fluorenylene, phenanthrenylene, triphenylenylene, pyrenylene, naphthacenylene, chrysenylene, biphenylenylene, anthracenylene, and naphthylene. At each occurrence, Z is independently chosen from a bond and —C≡C—. The variables j, R³, and R⁴are as defined herein.
FILED	Thursday, August 03, 2017
APPL NO	15/668390
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/08 (20130101) A01N 33/12 (20130101) A01N 43/50 (20130101) Original (OR) Class A01N 43/90 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/24 (20130101) A61L 15/46 (20130101) A61L 2300/404 (20130101) A61L 2420/02 (20130101) Heterocyclic Compounds C07D 233/64 (20130101) C07D 409/06 (20130101)
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10638956 — Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism

US 10638956	Candell et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Lawrence M. Candell (Arlington, Massachusetts); Christopher Ferraiolo (New Bedford, Massachusetts); Gary A. Shaw (Westford, Massachusetts); Andrew M. Siegel (Arlington, Massachusetts); George Zogbi (Arlington, Massachusetts); Holly Lehmann McClung (Westborough, Massachusetts); Reed Wasson Hoyt (Cambridge, Massachusetts); Kyle Thompson (Lynnfield, Massachusetts)
ABSTRACT	Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism of a subject include measuring a respiratory quotient (RQ) level in a subject and/or optimizing and executing a nonlinear feedback model to model energy substrate utilization in the subject based on at least one of a macronutrient composition and caloric value of food consumed by the subject, an intensity and duration of activity by the subject, a rate and maximum capacity of glycogen storage in the subject, a rate and maximum capacity of de novo lipogenesis in the subject, a quality and duration of sleep by the subject, and/or an RQ level in the subject.
FILED	Thursday, December 07, 2017
APPL NO	15/835049
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/083 (20130101) Original (OR) Class A61B 5/097 (20130101) A61B 5/0816 (20130101) A61B 5/0833 (20130101) A61B 5/0836 (20130101) A61B 5/0871 (20130101) A61B 5/4866 (20130101) A61B 5/7275 (20130101) A61B 2560/0223 (20130101) A61B 2560/0247 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) G09B 19/0092 (20130101)
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10638967 — Handheld radio device for assessing cognitive, auditory, visual, and speech function

US 10638967	Yanagi
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Office of Intellectual Property, Code 36000 (San Diego, California)
ASSIGNEE(S)	United States of America as represented by the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew A. Yanagi (Jamul, California)
ABSTRACT	A handheld radio device that incorporates within equipment typically carried by a first-responder but with added functionality which enables assessments of a subject's cognitive, auditory, visual, and speech function. In addition to providing two-way tactical radio functionality, the handheld radio device operates to generate haptic, audible, and visual stimuli, and then assess a subject utilizing the handheld radio device based on the subject's responses to the stimuli on the interfaces and sensors of the handheld radio device. Because this functionality is provided in equipment this is already typically carried by the first-responder, assessments that are more forward-deployed and closer to the point and time of injury, exposure, or period of interest can occur.
FILED	Monday, July 30, 2018
APPL NO	16/048859
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/10 (20130101) A61B 5/125 (20130101) A61B 5/742 (20130101) A61B 5/1112 (20130101) A61B 5/4076 (20130101) Original (OR) Class A61B 5/4803 (20130101) A61B 5/7405 (20130101) A61B 5/7455 (20130101) A61B 5/7475 (20130101) A61B 2562/06 (20130101) A61B 2562/0219 (20130101) A61B 2562/0223 (20130101) Transmission H04B 1/38 (20130101)
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10639233 — Optimal dosages for low energy shock wave treatment of vital organs

US 10639233	Lue et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tom Lue (Hillsborough, California); Ching-Shwun Lin (San Mateo, California); Guiting Lin (San Francisco, California); HongXiu Ning (San Francisco, California)
ABSTRACT	The treatment of various sensitive organs with low energy acoustic shockwaves has been proposed. However, the prior art is lacking in guidance as to what constitutes an efficacious minimum dosage or a safe maximum dosage for various target organs and tissues. Through extensive experimentation with cultured cells, live animals, and animal disease models, the inventors of the present disclosure have determined safe and efficacious shockwave energetic dosage ranges for vital and sensitive organs, including the brain, pancreas, kidneys, liver, and spleen, as well as for skin and subcutaneous tissues, peripheral nerves, and skeletal muscles.
FILED	Friday, March 11, 2016
APPL NO	15/067342
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/008 (20130101) Original (OR) Class
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10639277 — Multi-functional echogenic immunoliposomes for directed stem cell delivery to atheroma

US 10639277	Geng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Yong-Jian Geng (Pearland, Texas); David D. McPherson (Houston, Texas); Melvin E. Klegerman (Houston, Texas)
ABSTRACT	Disclosed are multifunctional-echogenic immunoliposome (MF-ELIP) constructs and compositions, and their methods of use to deliver attached stem cells to a target tissue such as atheroma, to enhance one or more of survival, growth, migration, activity and differentiation of the targeted stem cells, for treating, deterring or preventing mammalian atheroma and coronary artery disease.
FILED	Friday, February 02, 2018
APPL NO	15/887316
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101)
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10639450 — Medical device and delivery method onto offset surface of mammal tissue

US 10639450	McMurtry et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Fibralign Corporation (Union City, California)
ASSIGNEE(S)	FIBRALIGN CORPORATION (Union City, California)
INVENTOR(S)	David H. McMurtry (Felton, California); Michael V. Paukshto (Foster City, California); Tatiana S. Zaitseva (San Jose, California)
ABSTRACT	A novel medical device and a method for delivery of a scaffold for treatment of secondary lymphedema and ischemia is provided. In some embodiments a catheter medical device and a magnetic guidance method are provided for delivering cell-seeded implants for guided lymphatic regeneration.
FILED	Wednesday, July 24, 2013
APPL NO	14/417089
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/065 (20130101) A61B 17/0401 (20130101) A61B 17/3403 (20130101) A61B 17/3468 (20130101) A61B 2017/00004 (20130101) A61B 2017/0403 (20130101) A61B 2017/0409 (20130101) A61B 2017/0412 (20130101) A61B 2017/00792 (20130101) A61B 2017/00796 (20130101) A61B 2017/320056 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/01 (20130101) Original (OR) Class A61M 25/02 (20130101) A61M 25/0127 (20130101) A61M 37/0069 (20130101) A61M 2025/0166 (20130101)
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10639592 — Chitosan-graphene oxide membranes and process of making the same

US 10639592	Griggs et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
ASSIGNEE(S)	Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The United States of America, as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Christopher S. Griggs (Vicksburg, Mississippi); Jose A. Mattei-Sosa (Vicksburg, Mississippi); Luke A. Gurtowski (Vicksburg, Mississippi); Lauren F. Greenlee (Fayetteville, Arkansas); Mojtaba Abolhassani (Yazd, Iran)
ABSTRACT	This invention relates generally to a chitosan-graphene oxide membrane and process of making the same. The nanocomposite membrane can filter water and remove contaminants without fouling like other commercially-available polymer-based water filters. The membrane can be used as a flat sheet filter or can be engineered in a spiral filtration module. The membrane is scalable and tunable for many water contaminants including pharmaceuticals, pesticides, herbicides, and other organic chemicals. The membrane uses chitosan, which is low-cost, renewable biopolymer typically considered to be a waste product and the second most abundant biopolymer on Earth, thus making the membrane an environmentally-friendly product choice.
FILED	Tuesday, July 31, 2018
APPL NO	16/050425
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 63/10 (20130101) B01D 67/0011 (20130101) B01D 67/0013 (20130101) B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/06 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/08 (20130101) B01D 71/021 (20130101) B01D 71/024 (20130101) B01D 2315/10 (20130101) B01D 2325/28 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 2101/306 (20130101) C02F 2101/308 (20130101)
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10639696 — Apparatus and method for outer surface enhancement and compaction of a cylindrical structure using glass failure generated pulse

US 10639696	Dudt et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Philip Dudt (North Bethesda, Maryland); Roshdy George Barsoum (McLean, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Philip Dudt (North Bethesda, Maryland); Roshdy George Barsoum (McLean, Virginia)
ABSTRACT	An apparatus and method for treatment of articles, using glass failure generated pulses. The apparatus and method is directed towards the hardening and compaction of an elongated cylindrical article surrounded by a glass sleeve in a confined arrangement. The apparatus includes a striker for striking the glass sleeve to create an explosive reaction that pressure-treats the cylindrical article, thereby causing the hardening and compaction.
FILED	Friday, September 29, 2017
APPL NO	15/719868
ART UNIT	3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 26/08 (20130101) Original (OR) Class Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/06 (20130101) C21D 10/00 (20130101)
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10639711 — Nanowire-based magnets and methods of making same

US 10639711	Liu
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	J. Ping Liu (Colleyville, Texas)
ABSTRACT	The present invention achieves a high-energy product using Ferromagnetic 3D elements such as nanowires and methods of making the same. The high energy products or magnets of the invention are able to achieve high magnetization and maintain the magnetic properties at a greater range of temperatures than currently known magnets. For example, a high energy product includes at least one material A selected from the group consisting essentially of Fe, Co, and Ni, wherein material A is in the form of nanowires formed by a solvothermal chemical process. A high energy product may also include at least one material A selected from the group consisting essentially of Fe, Co, and Ni, and at least one material B selected from the group consisting essentially of Fe, Co, and Ni, wherein material A and material B are in the form of an alloy of nanowires formed by a solvothermal chemical process.
FILED	Monday, June 13, 2016
APPL NO	15/180939
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0025 (20130101) Original (OR) Class B22F 9/24 (20130101) B22F 2009/245 (20130101) B22F 2301/15 (20130101) B22F 2301/35 (20130101) B22F 2998/10 (20130101) Alloys C22C 19/07 (20130101) C22C 38/10 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101)
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10639721 — Systems and methods for additive manufacturing and repair of metal components

US 10639721	Das et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Suman Das (Atlanta, Georgia); Rohan Bansal (Buffalo, New York); Justin Gambone (Watervliet, New York)
ABSTRACT	Scanning Laser Epitaxy (SLE) is a layer-by-layer additive manufacturing process that allows for the fabrication of three-dimensional objects with specified microstructure through the controlled melting and re-solidification of a metal powders placed atop a base substrate. SLE can be used to repair single crystal (SX) turbine airfoils, for example, as well as the manufacture functionally graded turbine components. The SLE process is capable of creating equiaxed, directionally solidified, and SX structures. Real-time feedback control schemes based upon an offline model can be used both to create specified defect free microstructures and to improve the repeatability of the process. Control schemes can be used based upon temperature data feedback provided at high frame rate by a thermal imaging camera as well as a melt-pool viewing video microscope. A real-time control scheme can deliver the capability of creating engine ready net shape turbine components from raw powder material.
FILED	Friday, December 16, 2016
APPL NO	15/382411
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 5/04 (20130101) B22F 5/009 (20130101) B22F 7/062 (20130101) Original (OR) Class B22F 2003/1056 (20130101) B22F 2003/1057 (20130101) B22F 2007/068 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/007 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/08 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 13/24 (20130101) C30B 13/28 (20130101) C30B 13/32 (20130101) C30B 19/08 (20130101) C30B 19/10 (20130101) C30B 29/52 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101)
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10639801 — Low strain pneumatic networks for soft robots

US 10639801	Mosadegh et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Bobak Mosadegh (Boston, Massachusetts); Robert F. Shepherd (Brooktondale, New York); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	An actuator includes a plurality of chambers comprised of an extensible material, the chambers having interior side walls and exterior walls, wherein at least a portion of the interior side wall is separated from an interior side wall of an adjacent chamber; and a strain limiting base; and a channel that fluidically interconnects the plurality of chambers, wherein the interior walls are configured to be more compliant than the exterior walls.
FILED	Wednesday, August 20, 2014
APPL NO	14/464396
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 15/12 (20130101) B25J 15/0023 (20130101) Original (OR) Class B25J 18/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/70 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/00 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/08 (20130101) F15B 15/103 (20130101)
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10639847 — Method and apparatus for volumetric manufacture of composite objects

US 10639847	Birnbaum et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Andrew J. Birnbaum (Washington, District of Columbia); Athanasios Iliopoulos (Rockville, Maryland); John Steuben (Oxen Hill, Maryland); John G. Michopoulos (Washington, District of Columbia)
ABSTRACT	A method and apparatus for volumetric manufacture of three-dimensional physical objects from a precursor material based on plans, specifications, or virtual models. A build domain is provided comprising an enclosed three-dimensional wire grid in which the wires are connected to one or more electric power sources configured to controllably and addressably apply power to one or more individual wires to cause the wires to dissipate heat produced by Joule heating to the surrounding precursor material situated within the build domain, and to further allow for the control of the three-dimensional heat distribution and accordingly temperature distribution within the build domain. By activating and deactivating one or more predetermined subsets of the wires in the build domain, the precursor can be caused to melt and/or solidify so as to form a three-dimensional object within the build domain.
FILED	Tuesday, January 23, 2018
APPL NO	15/877675
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1056 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0266 (20130101) B29C 35/0272 (20130101) B29C 64/141 (20170801) B29C 64/165 (20170801) B29C 64/264 (20170801) B29C 64/295 (20170801) Original (OR) Class B29C 2035/0211 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) B29K 2105/0002 (20130101) B29K 2105/0058 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201)
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10640377 — Method for preparing clean insulating single or few sheets of topological insulators using an ionic liquid

US 10640377	Sutto et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Thomas E. Sutto (Woodbridge, Virginia); Amy Ng (Alexandria, Virginia); Nabil D. Bassim (Silver Spring, Maryland); Todd H. Brintlinger (Washington, District of Columbia); Michael S. Osofsky (Clarksville, Maryland); Rhonda Michele Stroud (Washington, District of Columbia)
ABSTRACT	A method to produce high quality single or a few atomic layers thick samples of a topological insulating layered dichalcogenide. The overall process involves grinding layered dichalcogenides, adding them to an ionic liquid, and then using a mechanical method to cause intercalation of the ionic liquid into the van der Waals (VDW) gap between the layers of the metal chalcogenide.
FILED	Wednesday, December 27, 2017
APPL NO	15/855023
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 19/04 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/08 (20130101) C01P 2004/24 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 17/56 (20130101)
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10640720 — Process for generating cool flame and flameless fuel oxidation using non-equilibrium plasma activation

US 10640720	Ju et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Yiguang Ju (Princeton, New Jersey); Sang Hee Won (Monmouth Juncton, New Jersey); Weiqi Sun (Princeton, New Jersey)
ABSTRACT	An exemplary embodiment can be an exemplary method, which can include, for example, generating a cool flame(s) using a plasma-assisted combustion, and maintaining the cool flame(s). The cool flame(s) can have a temperature below about 1050 Kelvin, which can be about 700 Kelvin. The cool flame(s) can be further generated using a heated counterflow burning arrangement and a an ozone generating arrangement. The heated counterflow burning arrangement can include a liquid fuel vaporization arrangement. The ozone generating arrangement can include a micro plasma dielectric barrier discharge arrangement. The plasma-assisted combustion can be generated using (i) liquid n-heptane, (i) heated nitrogen, and (iii) ozone.
FILED	Friday, April 03, 2015
APPL NO	15/301590
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 10/00 (20130101) Original (OR) Class Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 99/001 (20130101) F23C 2900/99001 (20130101) F23C 2900/99005 (20130101) Removal or Treatment of Combustion Products or Combustion Residues; Flues F23J 7/00 (20130101) Feeding Fuel to Combustion Apparatus F23K 2401/10 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/342 (20130101) Y02E 20/344 (20130101)
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10640762 — Methods for enhancing bacterial cell display of proteins and peptides

US 10640762	Daugherty et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Patrick Sean Daugherty (Santa Barbara, California); Jeffrey Rice (Goleta, California)
ABSTRACT	Methods of making and using bacterial display polypeptide libraries using circularly permuted OmpX (CPX) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of CPX.
FILED	Monday, June 05, 2017
APPL NO	15/613877
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/195 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/1037 (20130101) Original (OR) Class
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10640848 — Method of creating porous structures by particle expansion

US 10640848	Atwater et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Millersville University of Pennsylvania (Millersville, Pennsylvania)
ASSIGNEE(S)	Millersville University of Pennsylvania (Millersville, Pennsylvania); The United States of America As Represented By The Secretary Of The Army (Washington, District of Columbia)
INVENTOR(S)	Mark Andrew Atwater (Quarryville, Pennsylvania); Kris Allen Darling (Havre de Grace, Maryland); Mark Allen Tschopp, Jr. (Bel Air, Maryland)
ABSTRACT	A process for producing a metal foam. The process includes mechanically working a metallic powder such that oxide particles and/or dissolved oxygen are finely dispersed within a metallic matrix of the metallic particles that make up the metallic powder. The mechanically worked metallic powder is then annealed in a reducing atmosphere, where the reducing atmosphere is an atmosphere that results in the reduction of oxide and/or dissolved oxygen into vapor or gas molecules such that intraparticle porosity is formed within the metallic matrix by conversion of the oxide particles and/or dissolved oxygen to create vapor or gas molecules.
FILED	Monday, January 07, 2019
APPL NO	16/241345
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1143 (20130101) B22F 2009/043 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/08 (20130101) Original (OR) Class
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10640873 — Optical printing systems and methods

US 10640873	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Yuebing Zheng (Austin, Texas); Bharath Bangalore Rajeeva (Austin, Texas)
ABSTRACT	Disclosed herein are methods comprising: illuminating a first location of an optothermal substrate with electromagnetic radiation; wherein the optothermal substrate converts at least a portion of the electromagnetic radiation into thermal energy; and wherein the optothermal substrate is in thermal contact with a liquid sample comprising a plurality of thermally reducible metal ions; thereby: generating a confinement region at a location in the liquid sample proximate to the first location of the optothermal substrate; trapping at least a portion of the plurality of thermally reducible metal ions within the confinement region; and thermally reducing the trapped portion of the plurality of thermally reducible metal ions; thereby: depositing a metal particle on the optothermal substrate at the first location. Also disclosed herein are systems for performing the methods described herein. Also disclosed herein are patterned substrates made by the methods described herein, and methods of use thereof.
FILED	Thursday, December 20, 2018
APPL NO	16/227292
ART UNIT	2886 — Optics
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/182 (20130101) C23C 18/1612 (20130101) Original (OR) Class C23C 18/1667 (20130101) C23C 18/1817 (20130101) C23C 18/1865 (20130101) C23C 18/1868 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 2021/651 (20130101)
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10641099 — Impingement cooling for a gas turbine engine component

US 10641099	Waite et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Ryan Alan Waite (South Windsor, Connecticut); Matthew A. Devore (Rocky Hill, Connecticut)
ABSTRACT	An impingement cooled component includes a first wall having a plurality of impingement holes and a second wall spaced apart from the first wall. The second wall is downstream of the first wall, relative to a cooling flow, the second wall has a contoured surface facing the first wall. The contoured surface includes a plurality of contours defined by at least one of a plurality of peaks and a plurality of valleys, and at least one of the contours in the plurality of contours is aligned with an axis defined by one of the impingement holes in the plurality of impingement holes.
FILED	Monday, February 09, 2015
APPL NO	14/617228
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 5/187 (20130101) F01D 5/189 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/201 (20130101) F05D 2260/2212 (20130101) F05D 2260/22141 (20130101)
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10641103 — Trailing edge configuration with cast slots and drilled filmholes

US 10641103	Spangler
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Brandon W. Spangler (Vernon, Connecticut)
ABSTRACT	A gas turbine engine component comprises a body having a leading edge and a trailing edge. At least one internal channel is formed within the body, wherein the channel includes an inlet to direct cooling flow into the body. At least one cast slot is formed in the trailing edge. At least one drilled filmhole is formed in the trailing edge, wherein the cast slot and drilled filmhole direct flow from the internal channel to an external location from the body. A gas turbine engine, a method of manufacturing a gas turbine engine component, and a method of controlling flow in a gas turbine engine component.
FILED	Thursday, January 19, 2017
APPL NO	15/409613
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2260/202 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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10641106 — Gas turbine engines with improved airfoil dust removal

US 10641106	Crites et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S)	Daniel C Crites (Mesa, Arizona); Michael Kahrs (Phoenix, Arizona); Brandan Wakefield (Phoenix, Arizona); Ardeshir Riahi (Scottsdale, Arizona)
ABSTRACT	An airfoil for a rotor blade in a gas turbine engine includes a first side wall and a second side wall joined to the first side wall at a leading edge and a trailing edge. The airfoil further includes a tip cap extending between the first and second side walls such that the tip cap and at least portions of the first and second side walls form a blade tip and an internal cooling system. The internal cooling system includes a leading edge cooling circuit, a central cooling circuit, and a trailing edge cooling circuit. Each of the internal passages within the leading edge cooling circuit, the central cooling circuit, and the trailing edge cooling circuit is bounded in the radial outward direction with a surface that has at least one escape hole or that is positively angled in the radial outward direction relative to a chordwise axis.
FILED	Monday, November 13, 2017
APPL NO	15/810809
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/50 (20130101) F05D 2240/30 (20130101) F05D 2240/307 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) F05D 2260/607 (20130101) F05D 2260/2212 (20130101)
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10641108 — Turbine blade shroud for gas turbine engine with power turbine and method of manufacturing same

US 10641108	Bergman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Russell J. Bergman (South Windsor, Connecticut); Alan W. Stoner (Manchester, Tennessee)
ABSTRACT	A blade for a gas turbine engine includes an airfoil that includes an internal passage. A shroud is arranged at an end of the airfoil and has a shroud perimeter. Axially spaced knife edges extend radially from the shroud. An area is provided between the knife edges. A pocket is recessed into the area and is circumscribed by a perimeter edge that is arranged interiorly of the shroud perimeter. An outlet fluidly connects the internal passage to the pocket.
FILED	Friday, April 06, 2018
APPL NO	15/947254
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) Original (OR) Class F01D 5/147 (20130101) F01D 5/187 (20130101) F01D 5/225 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/21 (20130101) F05D 2240/11 (20130101) F05D 2240/55 (20130101) F05D 2240/307 (20130101) F05D 2260/20 (20130101) F05D 2260/202 (20130101)
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10641123 — Generator cooling impeller and bearing/rotor cooling

US 10641123	Narcus et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Andrew R Narcus (Loxahatchee, Florida); Cheryl A Schopf (Jupiter, Florida)
ABSTRACT	A power plant for an aircraft such as a UAV with a gas turbine engine that drives an electric generator to produce electrical power. The electric generator is rotatably supported by two foil bearings. A centrifugal compressor is secured to a forward side of the generator rotor shaft. The centrifugal compressor draws in cooling air that flows through the two foil bearings and between a space formed between the rotor coil and the stator coil of the electric generator to provide for cooling of both foil bearings and the coils of the generator.
FILED	Thursday, March 22, 2018
APPL NO	15/928489
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/042 (20130101) B64C 2201/048 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 2027/026 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/76 (20130101) F05D 2260/20 (20130101) Dynamo-electric Machines H02K 5/1672 (20130101) H02K 7/1823 (20130101) H02K 9/04 (20130101)
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10641129 — Support rail truss for gas turbine engines

US 10641129	Spangler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Brandon W. Spangler (Vernon, Connecticut); Jose R. Paulino (Saco, Maine); Craig R. McGarrah (Southington, Connecticut); Edward R. Bareiss (Stafford Springs, Connecticut); Edwin Otero (Southington, Connecticut)
ABSTRACT	A component for a gas turbine engine is disclosed. The component includes a platform and a rail having an outer radial surface and an inner radial surface, with the inner radial surface connected to the platform. The rail includes a plurality of apertures spaced circumferentially between the outer radial surface and the inner radial surface, the apertures disposed to form a truss-like structure.
FILED	Wednesday, November 08, 2017
APPL NO	15/806830
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) F01D 9/042 (20130101) F01D 11/08 (20130101) F01D 25/246 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/11 (20130101) F05D 2240/12 (20130101) F05D 2250/11 (20130101) F05D 2250/12 (20130101) F05D 2250/13 (20130101) F05D 2250/14 (20130101)
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10641180 — Hydrostatic non-contact seal with varied thickness beams

US 10641180	Gunderson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Peter E. Gunderson (West Hartford, Connecticut); Dwayne K. Mecklenburg (Stafford Springs, Connecticut)
ABSTRACT	A non-contact seal assembly includes a plurality of seal shoes arranged about a centerline in an annular array. The seal shoes include a first seal shoe extending axially along the centerline between a first shoe end and a second shoe end. A seal base circumscribes the annular array of the seal shoes. The assembly also includes a plurality of spring elements, each of the spring elements radially between and connecting a respective one of the seal shoes with the seal base. Each of the spring elements comprises a first beam having a first beam thickness and a second beam thickness, where the first and second beam thicknesses are different.
FILED	Thursday, June 15, 2017
APPL NO	15/623509
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) F01D 11/025 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/442 (20130101)
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10641184 — Dynamic flight command cross-feed for rotor speed droop reduction

US 10641184	Wulff et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	Ole Wulff (Ansonia, Connecticut); Derek Geiger (Wilton, Connecticut)
ABSTRACT	An aircraft and method of flying an aircraft are disclosed. The aircraft includes a cross-feed unit that receives a flight command for the aircraft and determines an amount of fuel for a motor of the aircraft in order to reduce a droop in the aircraft when executing the flight command at the aircraft. A fuel injector or fuel supplier provides the determined amount of fuel to the motor when the flight command is executed at the aircraft.
FILED	Wednesday, August 23, 2017
APPL NO	15/684009
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/28 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/329 (20130101) F05D 2270/07 (20130101) F05D 2270/024 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0858 (20130101)
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10641367 — Rotation of a pinion gear

US 10641367	Sharpes
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States, as represented but the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Nathan Sharpes (Abingdon, Maryland)
ABSTRACT	A pinion gear, with a varied gear ratio, can be inline with a rack. When the rack moves, the pinion gear can rotate. This rotation can cause an interior of an electrical generator to rotate. Rotation of the interior of the electrical generator can cause an electricity to be produced and outputted.
FILED	Thursday, November 30, 2017
APPL NO	15/827301
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Characteristic Features of Footwear; Parts of Footwear A43B 3/0015 (20130101) Gearing F16H 19/043 (20130101) Original (OR) Class F16H 35/02 (20130101) Dynamo-electric Machines H02K 7/1853 (20130101) H02K 7/1861 (20130101)
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10641558 — Multi-layered counterflow expanding microchannel cooling architecture and system thereof

US 10641558	Chainer et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Fanghao Yang (Somerset, New Jersey)
ABSTRACT	Devices that have integrated cooling structures for counterflow, two-phase cooling and systems thereof are provided. In one example, a first structure can comprise a first cooling channel. The first cooling channel can have a first value of width that increases as the first cooling channel extends from a first side of a heat transfer area towards a second side of the heat transfer area. Also, a second structure can comprise a second cooing channel. The second cooling channel can have a second value of width that increases as the second cooling channel extends from the second side of the heat transfer area towards the first side of the heat transfer area.
FILED	Thursday, May 09, 2019
APPL NO	16/407742
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0341 (20130101) F28D 15/00 (20130101) F28D 15/025 (20130101) F28D 15/0233 (20130101) F28D 15/0258 (20130101) F28D 15/0266 (20130101) F28D 2021/0028 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/12 (20130101) F28F 3/086 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 23/3736 (20130101) H01L 23/3737 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20309 (20130101)
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10641561 — Cased telescoped ammunition firearm with headspace reduction

US 10641561	Shipley et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Office of the Secretary of Defense (OSD) DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S)	AAI Corporation (Hunt Valley, Maryland)
ASSIGNEE(S)	AAI Corporation (Hunt Valley, Maryland)
INVENTOR(S)	Paul Andrew Shipley (Millers, Maryland); Gregory Paul Habiak (Bryn Mawr, Pennsylvania); Benjamin Tyler Cole (Baltimore, Maryland); Joshua Stephen Ruck (Baltimore, Maryland)
ABSTRACT	A weapon for firing cased telescoped (CT) ammunition includes a barrel. a chamber cavity aligned with the barrel, and a translating chamber member defining a chamber for holding a CT round for firing. The chamber member moves between a firing position in the chamber cavity and an ejection/loading position for ejecting a spent CT round and receiving a next CT round. A breech member closes a rear end of the chamber. A carrier performs a counter-recoil operation in which (1) the chamber member is moved from the ejection/loading position to the firing position with the next CT round therein, and (2) the breech is urged into a closed position against the next CT round in the chamber to remove headspace before the next CT round is fired from the weapon.
FILED	Tuesday, July 24, 2018
APPL NO	16/044384
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 3/10 (20130101) F41A 3/26 (20130101) F41A 3/30 (20130101) F41A 3/34 (20130101) Original (OR) Class F41A 9/23 (20130101) F41A 9/45 (20130101) F41A 15/14 (20130101) F41A 21/12 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/045 (20130101)
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10641584 — Energy absorbing structures for underbody blast protection

US 10641584	Bocchieri et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Robert T Bocchieri (Mountain View, California); Christina Wagner (Mountain View, California); Robert MacNeill (San Carlos, California); Steven W Kirkpatrick (Redwood City, California)
ABSTRACT	The present technology regards a de-coupled V-hull structure for use with an armored vehicle, and energy absorbing crush elements suitable for mounting the V-hull structure in a de-coupled manner to the vehicle. The energy absorbing V-hull structure includes a sloped armor structure forming a cavity having a v-shaped cross-section and a plurality of reinforcing elements, including a backbone, hull stiffeners and lateral supports. The elements are coupled together and supported by energy absorber mounts, extending along each side of the structure. Crush elements suitable for decoupling the V-hull structure are also disclosed, having a uniquely designed housing, a plurality of plates positioned within the housing, and affixation means for securing the crush element to the underside of the vehicle and to the top of the V-hull structure.
FILED	Thursday, August 02, 2018
APPL NO	16/053681
ART UNIT	3612 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Motor Vehicles; Trailers B62D 21/15 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/013 (20130101) F41H 7/042 (20130101) Original (OR) Class
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10641651 — Ultrasonic microphone and ultrasonic acoustic radio

US 10641651	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises 5 a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range
FILED	Wednesday, February 24, 2016
APPL NO	15/558467
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101)
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10641705 — Nanoplasmonic imaging technique for the spatio-temporal mapping of single cell secretions in real time

US 10641705	Raphael et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Marc P. Raphael (Springfield, Virginia); Joseph A. Christodoulides (Alexandria, Virginia); Jeff M. Byers (Fairfax Station, Virginia); James B. Delehanty (Washington, District of Columbia)
ABSTRACT	A label-free method for the spatio-temporal mapping of protein secretions from individual cells in real time by using a chip for localized surface plasmon resonance (LSPR) imaging. The chip is a glass coverslip compatible for use in a standard microscope having at least one array of functionalized plasmonic nanostructures patterned onto it. After placing a cell on the chip, the secretions from the cell are spatially and temporally mapped using LSPR imaging. Transmitted light imaging and/or fluorescence imaging may be done simultaneously with the LSPR imaging.
FILED	Monday, October 16, 2017
APPL NO	15/784433
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 21/274 (20130101) G01N 21/554 (20130101) Original (OR) Class G01N 21/648 (20130101) G01N 21/6458 (20130101) G01N 33/551 (20130101) G01N 33/54373 (20130101) G01N 2021/6491 (20130101)
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10641904 — Auxiliary global positioning system

US 10641904	Fleizach et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S)	United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gregory K. Fleizach (San Diego, California); Barry Hunt (San Diego, California)
ABSTRACT	A method of providing accurate position, navigation, and timing information comprising the steps of providing at least four transceiver devices, providing an auxiliary GPS device, and providing a receiver GPS device. Each transceiver devices receives a plurality of GPS signals from a plurality of GPS satellites, and calculates a transceiver position and transceiver velocity vector. The transceiver position, transceiver velocity vector, and GPS signal are repackaged at each transceiver into a first spread signal structure, which is transmitted from each transceiver as a first GPS-like signal. The GPS-like signal is received at an auxiliary GPS device, which generates a simulated GPS signal. This simulated GPS signal is then output and received by a simulated GPS device.
FILED	Wednesday, February 14, 2018
APPL NO	15/896974
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/09 (20130101) Original (OR) Class G01S 19/11 (20130101) G01S 19/243 (20130101) G01S 19/258 (20130101)
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10641924 — Automated tropical storm wind radii analysis and forecasting

US 10641924	Sampson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Charles R. Sampson (Aptos, California); John Knaff (Fort Collins, Colorado); Michael D. Frost (Monterey, California); Ann Schrader (Pacific Grove, California)
ABSTRACT	A computer-implemented system and methods that simplifies and improves the process for generating wind radii in tropical cyclones.
FILED	Thursday, September 07, 2017
APPL NO	15/697531
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Meteorology G01W 1/10 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/00 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101)
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10641925 — Formulation and fitting techniques for whole-atmosphere empirical models

US 10641925	Emmert et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	John T. Emmert (Dumfries, Virginia); Douglas P. Drob (Alexandria, Virginia); Julian Michael Picone (Falls Church, Virginia)
ABSTRACT	Systems and methods are provided for obtaining an empirical model of a planetary atmosphere as a function of the independent variables in a parametric formulation. Embodiments of the present disclosure can represent the temperature and individual species densities of the planetary atmosphere in the formulation, can robustly and efficiently carry out the computations needed to evaluate this formulation and to estimate the formulation's parameters, and can thereby obtain the empirical model of the planetary atmosphere.
FILED	Thursday, June 13, 2019
APPL NO	16/440092
ART UNIT	2631 — Digital Communications
CURRENT CPC	Meteorology G01W 1/10 (20130101) G01W 1/16 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/11 (20130101) G06F 2111/10 (20200101)
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10641930 — Holey optical device

US 10641930	Kildishev et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Alexander V. Kildishev (West Lafayette, Indiana); Satoshi Ishii (Hyogo, Japan); Vladimir M. Shalaev (West Lafayette, Indiana)
ABSTRACT	A method of making an optical device including forming a plurality of holes with varying radii milled vertically into a film, wherein said holes form a pattern. The radius of each hole determines an effective refractive index for said hole. The effective refractive index modifies a phase and an intensity of an incoming electromagnetic radiation as the radiation propagates through said hole. The device is configured to be operating equally for each linearly polarized radiation simultaneously, wherein the each linearly polarized radiation is normally incident on the device.
FILED	Tuesday, August 07, 2018
APPL NO	16/057130
ART UNIT	2872 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) G02B 3/08 (20130101) Original (OR) Class G02B 3/0087 (20130101) G02B 5/008 (20130101) G02B 6/262 (20130101) G02B 6/1225 (20130101) G02B 6/1226 (20130101) G02B 2207/101 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/397 (20130101) G02F 1/2255 (20130101) G02F 2203/06 (20130101) G02F 2203/13 (20130101) G02F 2203/50 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/888 (20130101)
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10641960 — Method and apparatus for assembling a fiber optic splice

US 10641960	Beranek et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Mark Beranek (Hollywood, Maryland); Nicholas Peterson (Minneapolis, Minnesota); Bradley Yost (Mechanicsville, Maryland); Michael Block (St. Leonard, Maryland)
ABSTRACT	A method and apparatus for assembling a fiber optic splice is provided. A first optical fiber end is inserted into a first clamp of the apparatus and a second optical fiber end is inserted into a second clamp of the apparatus. Situated between the first clamp and the second clamp is a curing chamber comprising a capillary tube containing resin and an ultra violet light. The first clamp moves a first distance, based on a first measured strain, towards the curing chamber. The second clamp is moved a second distance, based on a second measured strain, towards the curing chamber. The first clamp is then moved a third distance, based on a third measured strain, towards the curing chamber. The ultraviolet light is activated to cure the resin in the capillary tube.
FILED	Thursday, October 04, 2018
APPL NO	16/151992
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/25 (20130101) Original (OR) Class
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10641963 — Polarization-based filter stabilization of broadband light sources

US 10641963	Feke et al.
FUNDED BY	Department of Defense (DOD) Missile Defense Agency (MDA)
APPLICANT(S)	The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S)	Gilbert D. Feke (Windham, New Hampshire); Susannah M. Dickerson (Watertown, Massachusetts)
ABSTRACT	A broadband light source apparatus, and corresponding method, includes a broadband light source configured to provide broadband source light characterized by a source wavelength spectrum. The apparatus also includes a broadband optical filter including both a polarization changer with a length, as well as an exit polarizer. The broadband optical filter receives the source light and delivers broadband output light characterized by an output wavelength spectrum that is a function of the source wavelength spectrum and the polarization changer length and has an output centroid wavelength. The polarization changer length is configured to minimize a thermal sensitivity of the output centroid wavelength. The filter can be configured in view of a particular source wavelength spectrum to thermally stabilize the centroid wavelength and to maximize relative integrated output power passively with respect to ambient temperature fluctuations.
FILED	Friday, April 27, 2018
APPL NO	15/965821
ART UNIT	2874 — Optics
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) Optical Elements, Systems, or Apparatus G02B 6/2706 (20130101) Original (OR) Class G02B 6/2746 (20130101) G02B 6/29325 (20130101) G02B 6/29352 (20130101) G02B 6/29389 (20130101) G02B 6/29398 (20130101) G02B 27/288 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/09 (20130101) G02F 1/0136 (20130101) G02F 2203/21 (20130101) Transmission H04B 10/572 (20130101)
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10642270 — Aircrew automation system and method

US 10642270	Duda et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Aurora Flight Sciences Corporation (Manassas, Virginia)
ASSIGNEE(S)	Aurora Flight Sciences Corporation (Manassas, Virginia)
INVENTOR(S)	Jessica E. Duda (Wayland, Massachusetts); John Tylko (Manassas, Virginia); David Mindell (Manassas, Virginia); Fabrice Kunzi (Manassas, Virginia); Michael Piedmonte (Manassas, Virginia); John Allee (Manassas, Virginia); Joshua Torgerson (Manassas, Virginia); Jason Ryan (Malden, Massachusetts); James Donald Paduano (Boston, Massachusetts); John Brooke Wissler (Waltham, Virginia); Andrew Musto (Cambridge, Massachusetts); Wendy Feenstra (Manassas, Virginia)
ABSTRACT	An aircrew automation system and method for use in an aircraft. The aircrew automation system comprises one or more processors, an optical perception system, an actuation system, and a human-machine interface. The optical perception system monitors, in real-time, one or more cockpit instruments of the aircraft visually to generate flight situation data. The actuation system mechanically engages at least one flight control of the aircraft in response to the one or more flight commands. The human-machine interface provides an interface between a human pilot and the aircrew automation system. The human-machine interface comprises a display device to display a status of the aircraft and the actuation system.
FILED	Monday, July 08, 2019
APPL NO	16/504988
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 11/00 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) B64D 45/00 (20130101) B64D 2045/0075 (20130101) B64D 2045/0085 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Original (OR) Class G05D 1/101 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101)
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10642342 — Predicting voltage guardband and operating at a safe limit

US 10642342	Bertran et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Ramon Bertran (Bertran, New York); Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Jingwen Leng (Westchester, New York)
ABSTRACT	Methods and systems for executing an application includes executing an epoch of the application using a predicted minimum operational voltage that is based on a previous epoch of the application if the application is in a stable phase and using a nominal safe voltage if the application is in an unstable phase.
FILED	Wednesday, August 22, 2018
APPL NO	16/108373
ART UNIT	2187 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 1/3206 (20130101) G06F 1/3296 (20130101) Original (OR) Class Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/172 (20180101)
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10642345 — Avionics maintenance training

US 10642345	Godina et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Chad L. Godina (Elkhart, Indiana); Steven S. Montgomery (Indianapolis, Indiana); Scott E. Crawford (Prosper, Texas); Dean Allen Hoover (Noblesville, Indiana)
ABSTRACT	A virtual training system includes a computing processor, a virtual reality (VR) headset and a sensor to determine a VR hand position. The processor is configured according to computing instructions in a memory device for displaying a first VR scene that includes a first VR object. A second VR scene is displayed within a visual portal in the first VR scene that includes a second VR object. A user VR hand image is displayed in at least one of the first VR scene and the second VR scene based upon the determined VR hand position.
FILED	Tuesday, October 17, 2017
APPL NO	15/786234
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 17/00 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) Original (OR) Class G06F 3/0482 (20130101) G06F 3/0488 (20130101) G06F 3/04883 (20130101) G06F 2203/04803 (20130101) G06F 2203/04808 (20130101) Image Data Processing or Generation, in General G06T 15/20 (20130101) G06T 19/006 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/06 (20130101) G09B 5/065 (20130101)
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10642918 — Efficient publish/subscribe systems

US 10642918	Sahni et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Sartaj K. Sahni (Gainesville, Florida); Tania Banerjee (Gainesville, Florida)
ABSTRACT	A publish/subscribe system is described that can adjust to provide high performance for diverse application environments through an attribute structure based on predicates of a subscription, each attribute structure with one or more buckets to which attribute values of a subscription may be stored. Various data structures can be used in the attribute structure to locate the buckets containing the subscriptions. The data structures selected for each subscription are based on the attribute type and predicate operators of the subscription.
FILED	Friday, March 14, 2014
APPL NO	14/212107
ART UNIT	2163 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/958 (20190101) Original (OR) Class
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10642984 — Secure drive and method for booting to known good-state

US 10642984	Heagney
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Christopher Heagney (Jacksonville, Florida)
ABSTRACT	An apparatus and method of a secure drive is provided. The system includes a gate array, a non-volatile memory drive, and a power source. The non-volatile memory drive has secure, operational, and persistent memory spaces. The secure memory space is programmed with an encryption key and an encrypted disk image. In response to a power cycle, the gate array reads the encrypted disk image from the secure memory, authenticates the disk image using the encryption key, decrypts the encrypted disk image, and writes the decrypted disk image to the operational memory. The decrypted disk image is used to boot a computer. The computer is booted to a known good state each time the power is cycled.
FILED	Tuesday, June 12, 2018
APPL NO	16/006185
ART UNIT	2186 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 11/1441 (20130101) G06F 12/1408 (20130101) G06F 21/76 (20130101) G06F 21/79 (20130101) G06F 21/575 (20130101) Original (OR) Class G06F 2212/1052 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101)
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10643694 — Partial-polarization resistive electronic devices, neural network systems including partial-polarization resistive electronic devices and methods of operating the same

US 10643694	Alessandri et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S)	Cristobal Alessandri (Notre Dame, Indiana); Erich Kinder (Notre Dame, Indiana); Alan C. Seabaugh (Notre Dame, Indiana)
ABSTRACT	An electronic device can include a semiconductor material including a channel region configured to conduct a current, a source contact electrically coupled to the channel region at a first location, a drain contact electrically coupled to the channel region at a second location spaced apart from the first location, a partial-polarization material on the semiconductor material between the source contact and the drain contact opposite the channel region and a gate contact on the partial-polarization material opposite the channel region and ohmically coupled to the drain contact or ohmically coupled to the source contact.
FILED	Monday, November 05, 2018
APPL NO	16/180453
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/0635 (20130101) Static Stores G11C 13/0004 (20130101) G11C 13/004 (20130101) Original (OR) Class G11C 2213/73 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/147 (20130101)
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10643810 — Zero power plasmonic microelectromechanical device

US 10643810	Rinaldi et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Matteo Rinaldi (Boston, Massachusetts); Zhenyun Qian (Boston, Massachusetts); Sungho Kang (Boston, Massachusetts); Vageeswar Rajaram (Boston, Massachusetts)
ABSTRACT	A zero-power plasmonic microelectromechanical system (MEMS) device is capable of specifically sensing electromagnetic radiation and performing signal processing operations. Such devices are highly sensitive relays that consume no more than 10 nW of power, utilizing the energy in detected electromagnetic radiation to detect and discriminate a target without the need of any additional power source. The devices can continuously monitor an environment and wake up an electronic circuit upon detection of a specific trigger signature of electromagnetic radiation, such as vehicular exhaust, gunfire, an explosion, a fire, a human or animal, and a variety of sources of radiation from the ultraviolet to visible light, to infrared, to terahertz radiation.
FILED	Monday, August 22, 2016
APPL NO	15/753059
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0029 (20130101) B81B 2201/018 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 37/00 (20130101) Original (OR) Class H01H 37/02 (20130101) H01H 37/10 (20130101) H01H 37/46 (20130101) H01H 37/64 (20130101) H01H 37/72 (20130101) H01H 61/013 (20130101) H01H 2037/008 (20130101) H01H 2037/326 (20130101) H01H 2061/006 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0224 (20130101)
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10643961 — Substrate-less waveguide active circuit module

US 10643961	Chieh
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jia-Chi S. Chieh (San Diego, California)
ABSTRACT	A device includes an enclosure cover; a chip carrier attachable to and removable from the enclosure cover; and a ridge gap waveguide (RGW) cover. The chip carrier includes at least two cavities disposed on one surface and located on opposite sides, and each cavity has a slot extending to an opposite surface of the chip carrier. The RGW cover includes a plurality of ridges and a plurality of pillars disposed on one surface. The enclosure cover and the RGW cover are configured to connect to each other with the chip carrier located therebetween, and the opposite surface of the chip carrier faces the one surface of the RGW cover when the enclosure cover and the RGW cover are connected.
FILED	Thursday, December 20, 2018
APPL NO	16/228365
ART UNIT	2811 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4817 (20130101) H01L 23/053 (20130101) H01L 23/66 (20130101) Original (OR) Class H01L 24/48 (20130101) H01L 2223/6611 (20130101) H01L 2223/6683 (20130101) H01L 2224/48225 (20130101) H01L 2224/48455 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/123 (20130101) H01P 5/08 (20130101)
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10644114 — Reticulated shallow etch mesa isolation

US 10644114	Aifer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Edward H. Aifer (Arlington, Virginia); Igor Vurgaftman (Severna Park, Maryland); Jill A. Nolde (Arlington, Virginia); Eric M. Jackson (Alexandria, Virginia); Jerry R. Meyer (Catonsville, Maryland)
ABSTRACT	A device including an absorber layer that can be deposited on top of a bottom contact layer. Furthermore, a semi-intrinsic layer with an energy gap wider than that of the absorber layer can be deposited on top of the absorber layer. A top contact layer can be deposited on top of the semi-intrinsic layer. A conduction band and a valence band energy alignment can be positioned between the absorber layer and the top contact layer, and configured to allow photoexcited minority carriers to be collected while the flow of majority carriers from the absorber are blocked. At least one mesa can be formed by processing and removing layered materials to a depth at least near the bottom of the absorber layer. Finally, a shoulder can be formed in the at least one mesa within the semi-intrinsic layer by processing and removing the layered materials.
FILED	Wednesday, November 18, 2015
APPL NO	14/756417
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/15 (20130101) Original (OR) Class
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10644174 — High efficiency photovoltaic cells with self concentrating effect

US 10644174	Dutta
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Achyut Kumar Dutta (Sunnyvale, California)
ASSIGNEE(S)	Banpil Photonics, Inc. (Santa Clara, California)
INVENTOR(S)	Achyut Kumar Dutta (Sunnyvale, California)
ABSTRACT	This invention relates to a novel structure of photovoltaic devices (e.g. photovoltaic cells also called as solar cells) are provided. The cells are based on the micro or nano scaled structures which could not only increase the surface area but also have the capability of self-concentrating the light incident onto the photonics devices. More specifically, the structures are based on 3D structure including quintic or quintic-like shaped micor-nanostructures. By using such structures reflection loss of the light from the cell is significantly reduced, increasing the absorption, which results in increasing the conversion efficiency of the solar cell, and reducing the usage of material while increasing the flexibility of the solar cell. The structures can be also used in other optical devices wherein the reflection loss and absorption are required to enhanced to significantly improve the device performances.
FILED	Thursday, March 30, 2017
APPL NO	15/474232
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0236 (20130101) H01L 31/0296 (20130101) H01L 31/0352 (20130101) H01L 31/0547 (20141201) H01L 31/02168 (20130101) H01L 31/02363 (20130101) Original (OR) Class H01L 31/03529 (20130101) H01L 31/035281 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101)
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10644328 — Seawater electrolyte electrochemical cell

US 10644328	Smith
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	David Farnham Smith (Boulder Creek, California)
ASSIGNEE(S)	QYNERGY CORP. (Albuquerque, New Mexico)
INVENTOR(S)	David Farnham Smith (Boulder Creek, California)
ABSTRACT	An improved seawater electrochemical cell with a consumable anode and an oxygen reducing cathode is provided with a reduced distance between anode and cathode surfaces. The reduced distance does not impede the ingress of oxygen dissolved in water and the egress of reaction products from the cell and causes an increase in the volumetric energy and power density of such dissolved oxygen seawater cells.
FILED	Thursday, February 09, 2017
APPL NO	15/530631
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/34 (20130101) Original (OR) Class
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10644341 — Remotely-deployed benthic microbial fuel cell

US 10644341	Book et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jeffrey W. Book (Slidell, Louisiana); Leonard M. Tender (Bethesda, Maryland); Joel P. Golden (Fort Washington, Maryland); Andrew J. Quaid (New Orleans, Louisiana); Ian Martens (New Orleans, Louisiana)
ABSTRACT	A remotely-deployed benthic microbial fuel cell is provided, as well as a method for deploying the benthic microbial fuel cell. The remotely-deployed benthic microbial fuel cell has a mooring that includes a base unit, and a plurality of flukes mounted to a perimeter of a bottom portion of the base unit, the plurality of flukes being preconfigured to automatically move from a stored position to a deployed position. The benthic microbial fuel cell includes an anode that is mounted to the bottom portion of the base unit, and isolated from oxygenated water in an anoxic chamber by the plurality of flukes when in the deployed position. The benthic microbial fuel cell further includes a cathode that is attached to the base unit outside the anoxic chamber, where the cathode stays in oxygenated water when the remotely-deployed bottom mooring is deployed.
FILED	Wednesday, September 26, 2018
APPL NO	16/143076
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/00 (20130101) B63B 35/44 (20130101) B63B 2021/003 (20130101) B63B 2035/4466 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Original (OR) Class H01M 2250/20 (20130101)
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10644384 — Zero weight airborne antenna with near perfect radiation efficiency utilizing conductive airframe elements and method

US 10644384	Ozdemir et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Virtual EM Inc. (Ann Arbor, Michigan)
ASSIGNEE(S)	VIRTUAL EM INC. (, None)
INVENTOR(S)	Tayfun Ozdemir (Ann Arbor, Michigan); Christopher N. Davis (Ann Arbor, Michigan)
ABSTRACT	An aircraft includes a fuselage assembly including a first elongated structural member formed of electrically conductive material, at least one wing assembly including a second structural member formed of electrically conductive material, at least one horizontal stabilizer assembly including a third structural member formed of electrically conductive material, and at least one vertical stabilizer assembly including a fourth structural member formed of electrically conductive material. The wing assembly, the horizontal stabilizer, and the vertical stabilizer are each interconnected with the fuselage assembly in a flight configuration normal to the fuselage. The first, second, third and fourth structural members are electrically insulated from one another. An electronic communication device within the aircraft is configurable for selective electrical interconnection of two or more of said structural members to form a dipole or monopole type transmitting/receiving antenna.
FILED	Wednesday, September 25, 2019
APPL NO	16/582400
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/28 (20130101) Original (OR) Class H01Q 1/521 (20130101) H01Q 9/28 (20130101) H01Q 9/40 (20130101)
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10644391 — Cavity antenna with radome

US 10644391	Lavin et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Ronald O. Lavin (Gilbert, Arizona); Dennis K. McCarthy (Gilbert, Arizona); Andy H. Lee (Phoenix, Arizona); Manny S. Urcia (Wildwood, Missouri)
ABSTRACT	An antenna includes an antenna cavity structure that defines an antenna cavity and that has a cavity opening. The antenna also includes an antenna radiating element located within the cavity opening and operable to emit electromagnetic radiation that has a frequency and a wavelength and a radome structure covering the cavity opening. The radome structure includes a dielectric material and defines an antenna window that is transparent to the electromagnetic radiation. Due to the dielectric material of the radome structure, the antenna cavity has a depth less than one-fourth of the wavelength of the electromagnetic radiation and the cavity is filled with a low-dielectric material.
FILED	Tuesday, December 19, 2017
APPL NO	15/846307
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/42 (20130101) H01Q 1/422 (20130101) Original (OR) Class H01Q 7/00 (20130101) H01Q 9/0485 (20130101)
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10644539 — Method of making and using an apparatus for a locomotive micro-implant using active electromagnetic propulsion

US 10644539	Pivonka et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S)	Daniel Michael Pivonka (Palo Alto, California); Anatoly Anatolievich Yakovlev (Mountain View, California); Ada Shuk Yan Poon (Redwood City, California); Teresa H. Meng (Saratoga, California)
ABSTRACT	Described is a locomotive implant for usage within a predetermined magnetic field. In one embodiment magnetohydrodynamics is used to generate thrust with a plurality of electrodes. In another embodiment, asymmetric drag forces are used to generate thrust.
FILED	Friday, July 22, 2016
APPL NO	15/217815
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/00158 (20130101) A61B 5/07 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0116 (20130101) A61M 25/0127 (20130101) A61M 31/002 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 7/345 (20130101) H02J 50/10 (20160201) Original (OR) Class H02J 50/23 (20160201) H02J 50/27 (20160201) H02J 50/80 (20160201) H02J 50/90 (20160201)
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10645170 — Method and apparatus for control of multiple autonomous mobile nodes based on dynamic situational awareness data

US 10645170	Ranasinghe et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Episys Science, Inc. (Poway, California)
ASSIGNEE(S)	EpiSys Science, Inc. (Poway, California)
INVENTOR(S)	Nadeesha Oliver Ranasinghe (Torrance, California); Bong Kyun Ryu (Poway, California); Wei-Min Shen (Rancho Palos Verdes, California)
ABSTRACT	Techniques for autonomously establishing, maintaining, and repairing of a wireless communication network among multiple autonomous mobile nodes (AMN) are provided. The multiple AMNs are flown towards a first node. A tentacle is established with the first node and extended to cover a second node over a distance, thereby establishing a wireless communication network between the first node and the second node via the multiple AMNs. Any damage to the established wireless communication network or tentacle may be autonomously detected and repaired by using spare AMNs. Further, the communication network may be used to enable autonomous detection, tracking of the second node, as well as autonomous detection of a contamination area, based on data received from one or more sensors onboard the AMNs deployed in the air.
FILED	Saturday, December 30, 2017
APPL NO	15/859495
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Systems for Controlling or Regulating Non-electric Variables G05D 1/00 (20130101) G05D 1/104 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) G06K 9/6284 (20130101) G06K 9/6296 (20130101) G06K 9/6297 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/02 (20130101) G07C 5/08 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/021 (20130101) H04W 4/023 (20130101) H04W 24/10 (20130101) H04W 40/248 (20130101) H04W 72/0406 (20130101) H04W 76/11 (20180201) H04W 76/25 (20180201) H04W 84/005 (20130101) H04W 84/18 (20130101)
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10645367 — Systems, methods, and media for encoding and decoding signals used in time of flight imaging

US 10645367	Gupta et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Mohit Gupta (Madison, Wisconsin); Eric Breitbach (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin); Shree K. Nayar (New York, New York)
ABSTRACT	In accordance with some embodiments, systems, methods and media for encoding and decoding signals used in time-of-flight imaging are provided. In some embodiments, a method for estimating the depth of a scene is provided, comprising: causing a light source to emit modulated light toward the scene based on a modulation function; causing the image sensor to generate a first value based on the modulated light and a first demodulation function of K modulation functions, including at least one trapezoid wave; causing the image sensor to generate a second value; causing the image sensor to generate a third value; and determining a depth estimate for the portion of the scene based on the first value, the second value, and the third value.
FILED	Thursday, April 20, 2017
APPL NO	15/492969
ART UNIT	2482 — Recording and Compression
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4915 (20130101) G01S 17/32 (20130101) G01S 17/36 (20130101) G01S 17/89 (20130101) Pictorial Communication, e.g Television H04N 5/232 (20130101) H04N 13/161 (20180501) H04N 13/254 (20180501) H04N 13/271 (20180501) Original (OR) Class H04N 13/275 (20180501)
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10645378 — Focal plane illuminator for generalized photon transfer characterization of image sensor

US 10645378	Hendrickson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Aaron Hendrickson (Lexington Park, Maryland); Gary Lohman (Great Mills, Maryland)
ABSTRACT	A method and apparatus for characterizing a pixel of an image sensor is provided. The apparatus includes a narrowband, temporally incoherent, temporally stable illumination source. The narrowband light source generates a spatially coherent illumination beam. A variable optical attenuator attenuates the illumination beam resulting in an attenuated beam that does not alter the uniformity of the illumination. A focal plane integrator projects, expands, and homogenizes the attenuated beam to illuminate a focal plane of a sensor. Image sequences are collected to generate statistics for characterizing the sensor.
FILED	Monday, July 02, 2018
APPL NO	16/025406
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 26/00 (20130101) Pictorial Communication, e.g Television H04N 5/357 (20130101) H04N 5/369 (20130101) H04N 17/002 (20130101) Original (OR) Class
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10645812 — System and methods for additive manufacturing of electromechanical assemblies

US 10645812	MacCurdy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Robert MacCurdy (Ithaca, New York); Hod Lipson (New York, New York)
ABSTRACT	A hybrid additive manufacturing approach that incorporates three-dimensional (3D) printing and placement of modules selected from a library of modules to fabricate an electromechanical assembly. By virtue of fabrication of the electromechanical assembly, mechanical properties and electrical properties of the assembly are created. The invention overcomes the material and process limitations of current printable electronics approaches, enabling complete, complex electromechanical assemblies to be fabricated.
FILED	Tuesday, April 21, 2015
APPL NO	15/305962
ART UNIT	1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/00 (20170801) B29C 65/16 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 80/00 (20141201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/56 (20130101) H01L 21/67115 (20130101) H01L 21/67132 (20130101) H01L 23/5384 (20130101) H01L 23/5389 (20130101) H01L 25/18 (20130101) H01L 25/50 (20130101) H01L 25/112 (20130101) H01L 27/01 (20130101) H01L 27/13 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/14 (20130101) H05K 1/16 (20130101) H05K 1/113 (20130101) H05K 1/115 (20130101) H05K 1/117 (20130101) H05K 1/185 (20130101) Original (OR) Class H05K 1/0287 (20130101) H05K 3/0014 (20130101) H05K 3/30 (20130101) H05K 3/125 (20130101) H05K 3/284 (20130101) H05K 3/368 (20130101) H05K 3/4673 (20130101) H05K 3/4697 (20130101) H05K 2201/1003 (20130101) H05K 2201/10015 (20130101) H05K 2201/10022 (20130101) H05K 2201/10053 (20130101) H05K 2201/10106 (20130101) H05K 2201/10166 (20130101) H05K 2201/10174 (20130101) H05K 2201/10189 (20130101) H05K 2201/10636 (20130101) H05K 2203/107 (20130101) H05K 2203/1327 (20130101)
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10645840 — Active electronically steered array with waveguide manifold thermocoupled to ICS as a heatsink

US 10645840	Timmins et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	AvL Technologies, Inc. (Asheville, North Carolina)
ASSIGNEE(S)	AvL Technologies, Inc. (Asheville, North Carolina)
INVENTOR(S)	Ian J. Timmins (Seminole, Florida); Wayne Holt (Dacula, Georgia); Alan Ellis (Candler, North Carolina); Adam C. Gropp (Candler, North Carolina); Keith Edenfield (Weaverville, North Carolina); Bruce Barratt (Asheville, North Carolina)
ABSTRACT	A heatsink for heat dissipation amongst an active electronically steered array (AESA) on a printed circuit board (PCB) includes a metal plate having a first side and a second side; a plurality of integrally formed pockets on the first side of the metal plate each being sized and configured for congruent receipt of a corresponding one of a plurality of functional blocks of the AESA on the PCB; a plurality of waveguide manifolds on the second side of the metal plate including a plurality of holes that launch a wave transmission and a plurality of slots that guide the direction of the wave transmission; and wherein the metal plate prevents localized overheating amongst the AESA by positioning the metal plate on the PCB wherein the plurality of integrally formed pockets and the plurality of holes and the plurality of slots of the plurality of waveguide manifolds facilitate heat dissipation.
FILED	Monday, February 25, 2019
APPL NO	16/284824
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20154 (20130101) H05K 7/20163 (20130101) Original (OR) Class H05K 7/20536 (20130101)
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Department of Health and Human Services (HHS)

10638940 — Assessment of hemodynamic function in arrhythmia patients

US 10638940	Witschey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Walter R. T. Witschey (Philadelphia, Pennsylvania); Francisco Contijoch (San Diego, California); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Yuchi Han (Philadelphia, Pennsylvania)
ABSTRACT	Electrocardiogram (ECG)-gated cardiac magnetic resonance imaging (MRI) alone may be unable to capture the hemodynamics associated with arrhythmic events. As a result, values such as ejection fraction are acquisition dependent. The desired RR-duration determines the arrhythmia rejection. By combining real-time volume measurements with ECG recordings, beat morphologies can be categorized and a more comprehensive evaluation of ventricular function during arrhythmia can be provided.
FILED	Thursday, February 04, 2016
APPL NO	15/015373
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/02028 (20130101) Original (OR) Class A61B 5/7289 (20130101) A61B 2576/023 (20130101)
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10638949 — System and apparatus for assessing metallosis using magnetic resonance imaging

US 10638949	Koch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery (New York, New York); Medical College of Wisconsin (Milwaukee, Wisconsin)
ASSIGNEE(S)	New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery (New York, New York); Medical College of Wisconsin (Milwaukee, Wisconsin)
INVENTOR(S)	Kevin Matthew Koch (Wauwatosa, Wisconsin); Matthew F. Koff (Livingston, New Jersey); Hollis Potter (Greenwich, Connecticut)
ABSTRACT	A method includes: accessing MRI data acquired from a joint area, the MRI data including a series of spatially mapped spectral data points; generating MRI images of the joint area; receiving information encoding a region of interest that encompasses a suspected metal particle deposition area over at least one of the MRI images; constructing magnetic field maps using the MRI data, each representing off-resonance frequency shifts over the joint area; removing a background of off-resonance field inhomogeneity from the magnetic field map such that the region of interest is free from off-resonance field inhomogeneity; identifying clusters from the magnetic field maps with the background of off-resonance field inhomogeneity removed, the clusters defined over a first dimension of offset frequencies and a second dimension of cluster volumes; and computing a quantitative metric by combining information from the identified clusters according to both the first dimension and the second dimension.
FILED	Friday, April 21, 2017
APPL NO	15/494191
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/4528 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56 (20130101) G01R 33/243 (20130101) G01R 33/56536 (20130101)
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10638962 — Bio-adaptable implantable sensor apparatus and methods

US 10638962	Lucisano et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	GlySens Incorporated (San Diego, California)
ASSIGNEE(S)	GlySens Incorporated (San Diego, California)
INVENTOR(S)	Joseph Lucisano (San Diego, California); Timothy Routh (San Diego, California); Joe Lin (San Diego, California)
ABSTRACT	Biocompatible implantable sensor apparatus and methods of implantation and use. In one embodiment, the sensor apparatus is an oxygen-based glucose sensor having biocompatibility features that mitigate the host tissue response. In one variant, these features include use of a non-enzymatic membrane over each of the individual analyte detectors so as to preclude contact of the surrounding tissue with the underlying enzyme or other matrix, and mitigate vascularization, and insulation of the various electrodes and associated electrolytic processes of the sensor from the surrounding tissue. In one implementation, the sensor region of the implanted apparatus is configured to interlock or imprint the surrounding tissue so as to promote a high degree of glucose molecule diffusion into the individual detectors, and a constant and predictable sensor to blood vessel interface, yet preclude the tissue from bonding to the sensor, especially over extended periods of implant.
FILED	Wednesday, June 29, 2016
APPL NO	15/197104
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/6861 (20130101) A61B 5/14532 (20130101) A61B 5/14865 (20130101) Original (OR) Class A61B 2562/18 (20130101) A61B 2562/162 (20130101) A61B 2562/247 (20130101)
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10638981 — Method, system and computer readable medium for assessing actionable glycemic risk

US 10638981	Patek
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	Stephen D Patek (Charlottesville, Virginia)
ABSTRACT	A system, method and non-transient computer readable medium for assessing the opportunity to address either hyperglycemic or hypoglycemic risk (or both) in patients with diabetes based on historical continuous glucose monitoring (CGM) data.
FILED	Tuesday, February 16, 2016
APPL NO	15/551503
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/4839 (20130101) A61B 5/7225 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 2205/3584 (20130101) Electric Digital Data Processing G06F 17/12 (20130101) G06F 19/3418 (20130101) G06F 19/3468 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101)
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10639169 — Powered leg prosthesis and control methodologies for obtaining near normal gait

US 10639169	Goldfarb et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Michael Goldfarb (Franklin, Tennessee); Huseyin Atakan Varol (Astana, Kazakhstan); Frank Charles Sup, IV (Amherst, Massachusetts); Jason Mitchell (Greenbrier, Tennessee); Thomas J. Withrow (Brentwood, Tennessee)
ABSTRACT	A powered leg prosthesis including a powered knee joint with a knee joint and a knee motor unit for delivering power to the knee joint, a powered ankle joint coupled to the knee joint including an ankle joint and an ankle motor unit to deliver power to the ankle joint, a prosthetic foot coupled to the ankle joint, a plurality of sensors for measuring a real-time input, and controller for controlling movement of the prosthesis based on the real-time input. In the powered leg prosthesis, at least one of the knee motor unit or the ankle motor unit includes at least one drive stage, where the drive stage includes a rotary element for generating torque and at least one looped element affixed around the rotary element and configured for transmitting the torque to another rotary element coupled to a joint to be actuated.
FILED	Friday, October 16, 2015
APPL NO	14/885151
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) Original (OR) Class A61F 2/64 (20130101) A61F 2/68 (20130101) A61F 2/70 (20130101) A61F 2/6607 (20130101) A61F 2002/665 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/764 (20130101) A61F 2002/768 (20130101) A61F 2002/5073 (20130101) A61F 2002/6642 (20130101) A61F 2002/6657 (20130101) A61F 2002/6836 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/30359 (20130101) A61F 2220/0033 (20130101)
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10639175 — Porous bidirectional bellowed tracheal reconstruction device

US 10639175	Hollister et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Scott J. Hollister (Saline, Michigan); Glenn E. Green (Dexter, Michigan)
ABSTRACT	Implantable splinting devices for supporting a passageway defect in a patient that is formed from one or more support structures including a polymer or a polymer and acellularized tissue matrix that define a structural component that substantially conforms to a defective passageway of the patient. The structural component also has a plurality of pores. The implantable splinting device is capable of being placed around a trachea, a bronchi, an esophagus and a blood vessel of a patient. The implantable splinting device may also be configured for placement between the trachea, and the esophagus of a patient.
FILED	Monday, November 02, 2015
APPL NO	14/929555
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/94 (20130101) A61F 2/848 (20130101) Original (OR) Class A61F 2002/043 (20130101) A61F 2002/044 (20130101) A61F 2002/046 (20130101) A61F 2220/0008 (20130101) A61F 2220/0075 (20130101) A61F 2220/0091 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/005 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/16 (20130101) A61L 31/148 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) B29K 2105/251 (20130101) B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7534 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 67/04 (20130101)
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10639233 — Optimal dosages for low energy shock wave treatment of vital organs

US 10639233	Lue et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tom Lue (Hillsborough, California); Ching-Shwun Lin (San Mateo, California); Guiting Lin (San Francisco, California); HongXiu Ning (San Francisco, California)
ABSTRACT	The treatment of various sensitive organs with low energy acoustic shockwaves has been proposed. However, the prior art is lacking in guidance as to what constitutes an efficacious minimum dosage or a safe maximum dosage for various target organs and tissues. Through extensive experimentation with cultured cells, live animals, and animal disease models, the inventors of the present disclosure have determined safe and efficacious shockwave energetic dosage ranges for vital and sensitive organs, including the brain, pancreas, kidneys, liver, and spleen, as well as for skin and subcutaneous tissues, peripheral nerves, and skeletal muscles.
FILED	Friday, March 11, 2016
APPL NO	15/067342
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/008 (20130101) Original (OR) Class
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10639277 — Multi-functional echogenic immunoliposomes for directed stem cell delivery to atheroma

US 10639277	Geng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Yong-Jian Geng (Pearland, Texas); David D. McPherson (Houston, Texas); Melvin E. Klegerman (Houston, Texas)
ABSTRACT	Disclosed are multifunctional-echogenic immunoliposome (MF-ELIP) constructs and compositions, and their methods of use to deliver attached stem cells to a target tissue such as atheroma, to enhance one or more of survival, growth, migration, activity and differentiation of the targeted stem cells, for treating, deterring or preventing mammalian atheroma and coronary artery disease.
FILED	Friday, February 02, 2018
APPL NO	15/887316
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101)
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10639298 — Prodrugs of riluzole and their method of use

US 10639298	Wrobel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Biohaven Pharmaceutical Holding Company Ltd. (New Haven, Connecticut)
ASSIGNEE(S)	Biohaven Therapeutics Ltd. (New Haven, Connecticut)
INVENTOR(S)	Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey)
ABSTRACT	Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
FILED	Friday, February 26, 2016
APPL NO	15/549152
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/06026 (20130101)
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10639299 — Calcium sensing receptors, ligands, compositions, and methods of use

US 10639299	Yang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Georgia State University Research Foundation, Inc. (Atlanta, Georgia); University of Georgia Research Foundation, Inc. (Athens, Georgia); Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Georgia State University Research Foundation, Inc. (Atlanta, Georgia); University of Georgia Research Foundation, Inc. (Athens, Georgia); Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Jenny Jie Yang (Marietta, Georgia); Jian Hu (Atlanta, Georgia); Edward Brown (Atlanta, Georgia); Kelley Moremen (Athens, Georgia)
ABSTRACT	Described herein are compounds that can bind CaSR and/or a CaSR extracellular domain and formulations thereof. Also described herein are methods of inhibiting CaSR and/or treating a disease or disorder associated with a mutation in CaSR by administering a compound or formulation thereof described herein. Also described herein are assays that can be used to identify compounds that can bind an extracellular domain of CaSR.
FILED	Wednesday, March 29, 2017
APPL NO	16/090380
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) Original (OR) Class Peptides C07K 14/705 (20130101) C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/6872 (20130101) G01N 2500/02 (20130101)
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10639302 — Use of CDK9 inhibitors to reduce cartilage degradation

US 10639302	Haudenschild et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Dominik Haudenschild (Davis, California); Paul Di Cesare (Sacramento, California); Jasper Yik (Elk Grove, California); Blaine Christiansen (Woodland, California)
ABSTRACT	The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED	Tuesday, November 20, 2018
APPL NO	16/196955
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/453 (20130101) Original (OR) Class A61K 31/713 (20130101)
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10639306 — Aldose reductase inhibitors and uses thereof

US 10639306	Wasmuth et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Andrew Wasmuth (Brooklyn, New York); Donald W. Landry (New York, New York); Shixian Deng (White Plains, New York); Banavara L. Mylari (East Lyme, Connecticut); Ravichandran Ramasamy (Ardsley, New York); Ann Marie Schmidt (Franklin Lakes, New Jersey)
ABSTRACT	The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like.
FILED	Tuesday, March 05, 2019
APPL NO	16/293403
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/5025 (20130101) Original (OR) Class Heterocyclic Compounds C07D 487/04 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101)
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10639307 — Methods relating to the diagnosis and treatment of preeclampsia comprising administration of ADAMTS13 polypeptides

US 10639307	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Denisa D. Wagner (Dover, Massachusetts); Luise Erpenbeck (Boston, Massachusetts)
ABSTRACT	Described herein are methods, assays, and compositions relating to the treatment of thrombosis, preeclampsia, cancer, and intestinal inflammation, e.g., by administering ADAMTS13 to a subject in need of treatment.
FILED	Friday, May 13, 2016
APPL NO	15/573842
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4412 (20130101) A61K 38/36 (20130101) A61K 38/1767 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) A61P 13/12 (20180101) A61P 35/00 (20180101) A61P 43/00 (20180101)
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10639313 — Compound for inhibition of delta-5-desaturase (D5D) and treatment of cancer and inflammation

US 10639313	Qian et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	NDSU Research Foundation (Fargo, North Dakota)
ASSIGNEE(S)	NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S)	Yue (Steven) Qian (West Fargo, North Dakota); Pinjing Zhao (Fargo, North Dakota); Changhui Yan (Fargo, North Dakota)
ABSTRACT	Tricyclic compounds, including tricyclic iminodibenzylic and tricyclic iminostilbene compounds, are identified as therapeutic agents for inhibition of delta-5-desaturase (D5D) and for treating or preventing cancer and precancerous conditions, as well as autoimmune and inflammatory conditions. Pharmaceutical compositions and dietary supplements are provided, as are methods of administration and treatment.
FILED	Friday, August 31, 2018
APPL NO	16/118991
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) A61P 37/04 (20180101) Heterocyclic Compounds C07D 223/22 (20130101)
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10639321 — Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers

US 10639321	Zager et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington)
ASSIGNEE(S)	FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington)
INVENTOR(S)	Richard Zager (Mercer Island, Washington); Ali C M Johnson (Mill Creek, Washington)
ABSTRACT	The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism.
FILED	Monday, September 28, 2015
APPL NO	15/030008
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) A61K 31/555 (20130101) A61K 31/714 (20130101) Original (OR) Class A61K 33/26 (20130101) A61K 38/42 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101)
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10639345 — Compositions for preserving photoreceptor cells, retinal pigment epithelial cells, or visual function

US 10639345	Vavvas et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S)	Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S)	Demetrios G. Vavvas (Boston, Massachusetts); Georgios Trichonas (Boston, Massachusetts); Joan W. Miller (Winchester, Massachusetts); Yusuke Murakami (Newton, Massachusetts)
ABSTRACT	Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.
FILED	Friday, October 26, 2018
APPL NO	16/171837
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/028 (20130101) A61B 5/4839 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0008 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/195 (20130101) A61K 31/195 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 31/4174 (20130101) A61K 31/4174 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 38/005 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10639349 — H3T3A mutant protein efficiently reduces H3T3P and causes increased cell death of rapidly dividing cells

US 10639349	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Xin Chen (Baltimore, Maryland); Jing Xie (Ellicott City, Maryland)
ABSTRACT	The invention features compositions comprising an H3T3A mutant protein. Described herein are methods of inducing cell death in a rapidly dividing cell comprising contacting a rapidly dividing cell with an agent that reduces phosphorylation at threonine 3 of histone 3 (H3T3P), thereby inducing cell cycle arrest followed by cell death. In some cases, the rapidly dividing cell is a tumor cell, e.g., a cancer cell. The agent that reduces phosphorylation of H3T3P comprises an H3T3A mutant protein, e.g., a mutant transgenic protein. Described herein is a kit for arresting cell cycle comprising an agent that reduces phosphorylation H3T3P.
FILED	Wednesday, April 06, 2016
APPL NO	15/565120
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/47 (20130101) C07K 16/3053 (20130101) C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 2333/4722 (20130101) G01N 2800/50 (20130101)
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10639354 — Treatment of hyperinsulinemic hypoglycemia with exendin (9-39)

US 10639354	McLaughlin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S)	The BOT of The Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)
INVENTOR(S)	Tracey L. McLaughlin (Stanford, California); Colleen M. Craig (Stanford, California)
ABSTRACT	Compositions and methods for treating hyperinsulinemic hypoglycemia, such as hyperinsulinemic hypoglycemia after bariatric surgery or gastrointestinal surgery, are provided. In some embodiments, an effective amount of the glucagon-like peptide-1 receptor antagonist exendin(9-39) is subcutaneously administered twice per day.
FILED	Monday, May 23, 2016
APPL NO	15/576647
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 38/17 (20130101) A61K 38/22 (20130101) A61K 38/26 (20130101) A61K 38/2278 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101)
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10639363 — Cancer immunotherapy using virus particles

US 10639363	Steinmetz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN REVERSE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Nicole F. Steinmetz (Cleveland, Ohio); Amy M. Wen (Cleveland, Ohio); Steven Fiering (Cleveland, Ohio); Patrick H. Lizotte (Cleveland, Ohio)
ABSTRACT	A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
FILED	Monday, May 08, 2017
APPL NO	15/589677
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/544 (20130101) A61K 2039/585 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/00023 (20130101) C12N 2770/00034 (20130101) C12N 2770/00071 (20130101) C12N 2770/32022 (20130101) C12N 2770/32023 (20130101) C12N 2770/32034 (20130101) C12N 2770/32071 (20130101)
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10639366 — Use of inactivated nonreplicating modified vaccinia virus Ankara (MVA) as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors

US 10639366	Deng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Memorial Sloan-Kettering Cancer Center (New York, New York)
ASSIGNEE(S)	Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S)	Liang Deng (New York, New York); Stewart Shuman (New York, New York); Jedd D. Wolchok (New York, New York); Taha Merghoub (New York, New York); Peihong Dai (New York, New York); Weiyi Wang (New York, New York)
ABSTRACT	The present disclosure relates to infection-competent, but nonreplicative inactivated modified vaccinia Ankara (MVA) and its use as immunotherapy, alone, or in combination with immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to inducing an immune response in a subject diagnosed with a solid malignant tumor.
FILED	Thursday, February 25, 2016
APPL NO	15/553222
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/12 (20130101) A61K 39/285 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/585 (20130101) A61K 2039/5252 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24132 (20130101) C12N 2710/24134 (20130101)
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10639380 — Flavivirus-binding, entry-obstructing, protease-resistant peptide (RI57)

US 10639380	Michael et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Scott F. Michael (Estero, Florida); Sharon Isern (Estero, Florida)
ASSIGNEE(S)	ENNAID THERAPEUTICS, LLC (Alpharetta, Georgia)
INVENTOR(S)	Scott F. Michael (Estero, Florida); Sharon Isern (Estero, Florida)
ABSTRACT	The invention pertains to inhibitors bindable to regions of a virus. More particularly, the invention relates to inhibitors bindable to regions of flaviviral envelope glycoprotein, or flaviviral virus E protein, a class II viral E protein. Even more particularly, the invention relates to peptides inhibitory to virus-to-cell fusion and virus entry into animal cells. The invention also contains methods of determining said inhibitors, bindable to regions of the flaviviral E protein complex, (e.g., those of dengue and zika viruses) as candidates for in vivo anti-viral compounds that are also resistant to degradation by peptidases and thus extraordinarily suitable for oral, in addition to other, routes of administration.
FILED	Tuesday, December 06, 2016
APPL NO	15/369893
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/643 (20170801) Original (OR) Class Peptides C07K 14/001 (20130101) Technologies for Adaptation to Climate Change Y02A 50/385 (20180101) Y02A 50/391 (20180101)
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10639473 — Neural prosthesis system and method of control

US 10639473	Moss et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Christa Wheeler Moss (Cleveland Heights, Ohio); Paul Hunter Peckham (Cleveland Heights, Ohio)
ABSTRACT	Multiple designs, systems, methods and processes for control using electrical signals recorded from clinically paralyzed muscles and nerves are presented. The discomplete neural prosthesis system and method for clinically paralyzed humans utilizes a controller. The controller is adapted to receive a volitional electrical signal generated by the human that is manifest below the lesion that causes the clinical paralysis. The controller uses at least the volitional electrical signal to generate a control signal that is output back to a plant to change the state of the plant, which in one aspect is one or more of the user's paralyzed muscles to achieve a functional result or to devices in the environment around the user that are adapted to receive commands from the controller.
FILED	Friday, December 29, 2017
APPL NO	15/857971
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36003 (20130101) Original (OR) Class A61N 1/36017 (20130101) A61N 1/36067 (20130101) A61N 1/36135 (20130101)
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10640457 — Histone acetyltransferase activators and uses thereof

US 10640457	Feng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Yan Feng (Shanghai, China PRC); Mauro Fa (New York, New York); Ottavio Arancio (New York, New York); Shixian Deng (White Plains, New York); Donald W. Landry (New York, New York); Yitshak Francis (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Yan Feng (Shanghai, China PRC); Mauro Fa (New York, New York); Ottavio Arancio (New York, New York); Shixian Deng (White Plains, New York); Donald W. Landry (New York, New York); Yitshak Francis (New York, New York)
ABSTRACT	The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject.
FILED	Monday, June 11, 2012
APPL NO	13/493490
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 235/56 (20130101) C07C 235/64 (20130101) Original (OR) Class C07C 237/40 (20130101) C07C 323/42 (20130101) C07C 323/44 (20130101) C07C 323/60 (20130101) C07C 323/67 (20130101) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 213/75 (20130101) C07D 213/82 (20130101) C07D 239/52 (20130101) C07D 333/38 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) G01N 2800/2814 (20130101)
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10640494 — N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof

US 10640494	Malamas et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	NORTHEASTERN UNIVERSITY (Boston, Massachusetts)
INVENTOR(S)	Michael Malamas (Jamison, Pennsylvania); Alexandros Makriyannis (Watertown, Massachusetts); Kumara Vadivel Subramanian (Boston, Massachusetts); Kyle M. Whitten (Boston, Massachusetts); Nikolai M. Zvonok (Boston, Massachusetts); Jay Matthew West (Boston, Massachusetts); Michael McCormack (Boston, Massachusetts); Spiro Pavlopoulos (Boston, Massachusetts)
ABSTRACT	A compound is represented as Formula I, a tautomer thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof: Compounds of Formula I are inhibitors of N-acylethanolamine hydrolyzing acid amidase (NAAA).
FILED	Friday, March 30, 2018
APPL NO	15/942345
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 255/46 (20130101) C07C 331/20 (20130101) C07C 331/24 (20130101) C07C 331/26 (20130101) C07C 2601/04 (20170501) C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/12 (20130101) C07D 211/10 (20130101) C07D 211/26 (20130101) C07D 211/46 (20130101) C07D 213/30 (20130101) C07D 213/36 (20130101) C07D 213/46 (20130101) C07D 213/64 (20130101) C07D 231/12 (20130101) C07D 239/26 (20130101) C07D 239/28 (20130101) C07D 241/18 (20130101) C07D 261/08 (20130101) C07D 295/13 (20130101) C07D 295/135 (20130101) C07D 317/54 (20130101) C07D 317/58 (20130101) C07D 319/18 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) Original (OR) Class C07D 413/12 (20130101)
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10640502 — Therapeutic targeting of interleukin-1 receptor-associated kinase 4 (IRAK4) in cancers characterized by rearrangements in the mixed lineage leukemia gene (MLL-r)

US 10640502	Shilatifard et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ali Shilatifard (Chicago, Illinois); Kaiwei Liang (Chicago, Illinois); Edwin Richard Smith (Chicago, Illinois); Gary E. Schiltz (Naperville, Illinois)
ABSTRACT	Disclosed are methods for treating cancers associated with rearrangements in the mixed lineage leukemia gene (MLL-r), including MLL-r leukemia. The methods typically include administering a therapeutic amount of one or more therapeutic agents that inhibit the biological activity of one or more members of the interleukin-1 signaling pathway such inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4).
FILED	Monday, July 09, 2018
APPL NO	16/030046
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 233/88 (20130101) C07D 471/04 (20130101) Original (OR) Class
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10640508 — Diazene directed modular synthesis of compounds with quaternary carbon centers

US 10640508	Movassaghi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Mohammad Movassaghi (Arlington, Massachusetts); Petra Lindovska (Cambridge, Massachusetts)
ABSTRACT	Diazene-directed modular synthesis is described for the preparation Csp2-Csp3 and Csp3-Csp3 linkages where one or more stereogenic quaternary carbon centers are formed. The disclosed methods are directed to the preparation of compounds of Formula (I), or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, from compounds of Formula (II): wherein R¹-R⁵and q are as defined independently for each occurrence herein. A wide variety of compounds can be accessed in this manner, including oligocyclotryptamines, where the stereochemistry of each subunit is beneficially secured before fragment coupling.
FILED	Monday, October 15, 2018
APPL NO	16/161036
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class
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10640530 — Method for facilitating extraction of a fraction from a biological sample

US 10640530	Beebe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	David Beebe (Monona, Wisconsin); Lindsay Strotman (Madison, Wisconsin); Scott M. Berry (Madison, Wisconsin)
ABSTRACT	A method is provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The method includes the steps of capturing the fraction-bound solid phase substrate and bringing an isolation buffer and the fraction-bound solid phase substrate into contact to purify the captured fraction-bound solid phase substrate.
FILED	Thursday, February 08, 2018
APPL NO	15/891978
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 1/14 (20130101) Original (OR) Class C07K 1/145 (20130101)
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10640535 — Identification of MHC class I phospho-peptide antigens from breast cancer utilizing SHLA technology and complementary enrichment strategies

US 10640535	Hunt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Agenus Inc. (Lexington, Massachusetts); The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	AGENUS INC. (Lexington, Massachusetts); THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma)
INVENTOR(S)	Donald F. Hunt (Charlottesville, Virginia); Andrew Norris (Palmyra, Virginia); Ann Michelle English (Palmyra, Virginia); Jeffrey Shabanowitz (Charlottesville, Virginia); William H. Hilderbrand (Edmond, Oklahoma); Oriana E. Hawkins (Tuscola, Texas)
ABSTRACT	The present invention describes novel tumor-specific phosphorylated peptides, nucleic acids encoding those peptides, and antibodies generated against said peptides. The genes, peptides, and antibodies described herein may be used as diagnostic indicators of the presence of breast cancer and/or used in therapeutics to treat breast cancer.
FILED	Tuesday, May 28, 2013
APPL NO	14/403350
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class C07K 14/4748 (20130101) C07K 16/18 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101)
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10640553 — Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy

US 10640553	Milone et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Novartis AG (Basel, Switzerland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Novartis AG (Basel, Switzerland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Michael Milone (Cherry Hill, New Jersey); Enxiu Wang (Upper Darby, Pennsylvania)
ABSTRACT	The present invention provides compositions and methods for regulating the specificity and activity of T cells. In one embodiment, the invention provides a type of chimeric antigen receptor (CAR) wherein the CAR is termed a “KIR-CAR” which is a CAR design comprising a component of a receptor naturally found on natural killer (NK) cells. In one embodiment, the NK receptor includes but is not limited to a naturally occurring activating and inhibitory receptor of NK cells known as a killer cell immunoglobulin-like receptor (KIR).
FILED	Monday, July 24, 2017
APPL NO	15/658115
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/70503 (20130101) C07K 14/70535 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101)
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10640561 — Methods for manipulating phagocytosis mediated by CD47

US 10640561	Jaiswal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Siddhartha Jaiswal (San Francisco, California); Irving L. Weissman (Stanford, California); Ravindra Majeti (Palo Alto, California); Mark P. Chao (Mountain View, California)
ABSTRACT	Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e.g. circulating hematopoietic cells, bone marrow cells, acute leukemia cells, etc.; and solid tumor cells. In some embodiments of the invention the circulating cells are hematopoietic stem cells, or hematopoietic progenitor cells, particularly in a transplantation context, where protection from phagocytosis is desirable. In other embodiments the circulating cells are leukemia cells, particularly acute myeloid leukemia (AML), where increased phagocytosis is desirable.
FILED	Tuesday, July 18, 2017
APPL NO	15/652950
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/6851 (20170801) A61K 47/6861 (20170801) A61K 47/6863 (20170801) A61K 47/6865 (20170801) A61K 47/6867 (20170801) A61K 47/6869 (20170801) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3061 (20130101) C07K 16/3069 (20130101) C07K 2317/31 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101)
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10640569 — Human mesothelin chimeric antigen receptors and uses thereof

US 10640569	Beatty et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Novartis AG (Basel, Switzerland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Novartis AG (Basel, Switzerland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Gregory Beatty (Philadelphia, Pennsylvania); Boris Engels (Cambridge, Massachusetts); Neeraja Idamakanti (Cambridge, Massachusetts); Carl H. June (Merion Station, Pennsylvania); Andreas Loew (Cambridge, Massachusetts); Huijuan Song (Shanghai, China PRC); Qilong Wu (Shanghai, China PRC)
ABSTRACT	Provided are compositions and methods for treating diseases associated with expression of mesothelin. Also provided are a chimeric antigen receptor(CAR) specific to mesothelin, vectors encoding the same, and recombinant T cells comprising the mesothelin CAR. Further provided are methods of administering a genetically modified T cell expressing a CAR that comprises a mesothelin binding domain.
FILED	Friday, December 19, 2014
APPL NO	15/105082
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 38/00 (20130101) A61K 38/1774 (20130101) A61K 38/1793 (20130101) A61K 39/0011 (20130101) A61K 39/39558 (20130101) A61K 48/0058 (20130101) A61K 2039/505 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/7151 (20130101) C07K 14/70517 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/303 (20130101) C07K 16/3061 (20130101) C07K 16/3069 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2740/15041 (20130101)
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10640571 — Human monoclonal antibodies specific for glypican-3 and use thereof

US 10640571	Ho et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Mitchell Ho (Urbana, Maryland); Mingqian Feng (Rockville, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Wei Gao (Rockville, Maryland)
ABSTRACT	Described herein is the identification of human monoclonal antibodies that bind GPC3 or heparan sulfate (HS) chains on GPC3 with high affinity. The antibodies described herein are capable of inhibiting HCC cell growth and migration. Provided are human monoclonal antibodies specific for GPC3 or HS chains on GPC3, including immunoglobulin molecules, such as IgG antibodies, as well as antibody fragments, such as single-domain VH antibodies or single chain variable fragments (scFv). Further provided are compositions including the antibodies that bind GPC3 or HS chains on GPC3, nucleic acid molecules encoding these antibodies, expression vectors comprising the nucleic acids, and isolated host cells that express the nucleic acids. Methods of treating cancer and/or inhibiting tumor growth or metastasis are also provided. Further provided are methods of detecting cancer in a subject and confirming a diagnosis of cancer in a subject.
FILED	Friday, December 15, 2017
APPL NO	15/843256
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/6803 (20170801) A61K 47/6813 (20170801) A61K 47/6829 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 2039/505 (20130101) Peptides C07K 14/21 (20130101) C07K 16/28 (20130101) C07K 16/303 (20130101) C07K 16/3076 (20130101) Original (OR) Class C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/41 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/33 (20130101) C07K 2319/55 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/57438 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101) G01N 2400/40 (20130101)
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10640742 — Hybrid linear actuator controlled hydraulic cell stretching

US 10640742	McCarthy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Kevin John McCarthy (Shreveport, Louisiana); Deborah Jane Wassenhove-McCarthy (Shreveport, Louisiana)
ABSTRACT	A hydraulic cell stretching device comprising a source of variable pressured hydraulic fluid hydraulically coupled to a flexing chamber. The flexing chamber has at least one cell well. The cell well has a membrane subjected to the variable pressured hydraulic fluid.
FILED	Friday, September 25, 2015
APPL NO	14/865464
ART UNIT	1799 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 25/04 (20130101) C12M 35/04 (20130101) C12M 41/48 (20130101) C12M 43/00 (20130101) C12M 47/00 (20130101)
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10640744 — Electromechanical lysis of bacterial pathogens using ion concentration polarization

US 10640744	Kim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Minseok Kim (Medford, Massachusetts); Jongyoon Han (Bedford, Massachusetts)
ABSTRACT	Scalable, high throughput and power-efficient electromechanical lysis using low electric potential, which can be used for harvesting valuable intracellular biomolecules (DNA, RNA, and proteins) and metabolites (e.g., biodiesels, bioplastics, antibiotics, and antibodies), and for sterilizing large volume solutions (e.g. disinfection of bacterial contaminated drinking water). The method can be directly integrated with other microfluidic devices for all-in-one, fully integrated total-analysis systems for various bacterial (and cellular) studies and clinical applications.
FILED	Tuesday, October 10, 2017
APPL NO	15/728860
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) Original (OR) Class C12N 13/00 (20130101)
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10640747 — Biomatrix scaffolds for industrial scale dispersal

US 10640747	Roach et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Institute of Dental and Craniofacial Research (NIDCR) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Marsha Lynn Roach (Branford, Connecticut); Richard Harold Malavarca (Long Valley, New Jersey); Yunfang Wang (Beijing, China PRC); Lola M. Reid (Chapel Hill, North Carolina)
ABSTRACT	The present invention provides biomatrix scaffolds for industrial scale dispersal.
FILED	Thursday, April 12, 2018
APPL NO	15/952094
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/3604 (20130101) A61L 27/3683 (20130101) A61L 27/3691 (20130101) A61L 2430/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0068 (20130101) Original (OR) Class C12N 5/0671 (20130101) C12N 5/0693 (20130101) C12N 7/00 (20130101) C12N 2500/25 (20130101) C12N 2500/36 (20130101) C12N 2501/20 (20130101) C12N 2501/998 (20130101) C12N 2506/14 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101)
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10640750 — Ultrasound technology to control the spatial organization of cells and proteins in engineered tissues

US 10640750	Dalecki et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	University of Rochester (Rochester, New York)
ASSIGNEE(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S)	Diane Dalecki (Rochester, New York); Denise Hocking (Rochester, New York); Kelley Garvin (San Jose, California)
ABSTRACT	The present invention is directed to methods of inducing spatial organization of cells an in vitro culture system using ultrasound technology. The invention is further directed to methods of inducing extracellular matrix remodeling and neovessel formation in an in vitro culture system and generating vascularized engineered tissue constructs using ultrasound technology.
FILED	Friday, May 26, 2017
APPL NO	15/606828
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 35/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/069 (20130101) Original (OR) Class C12N 5/0656 (20130101) C12N 13/00 (20130101) C12N 2521/10 (20130101) C12N 2533/52 (20130101) C12N 2533/54 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/68 (20130101)
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10640767 — Assay for exo-site binding molecules

US 10640767	Maianti et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Juan Pablo Maianti (Revere, Massachusetts); David R. Liu (Lexington, Massachusetts)
ABSTRACT	Methods for the identification of agents the bind to exo-sites of proteins are provided. Agents identified by the methods described herein and pharmaceutical compositions comprising the identified agents are also provided. Methods of using an identified agent for the treatment or prevention of a disease, disorder, or condition are also provided, including methods of treating or preventing a disease associated with reduced, elevated, or ectopic expression or aberrant activity of a protein comprising an exo-site.
FILED	Wednesday, October 31, 2018
APPL NO	16/177141
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Original (OR) Class C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2537/159 (20130101) C12Q 2563/179 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/04 (20130101) C40B 40/10 (20130101) C40B 40/14 (20130101)
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10640771 — Compositions and methods for treating and preventing macular degeneration

US 10640771	Wadsworth et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	GENZYME CORPORATION (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S)	GENZYME CORPORATION (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE (Rockville, Maryland)
INVENTOR(S)	Samuel Wadsworth (Shrewsbury, Massachusetts); Abraham Scaria (Framingham, Massachusetts); Chi-Chao Chan (Burlingame, California)
ABSTRACT	Compositions and methods for treating macular degeneration are disclosed. The methods utilize IL17 inhibitors, such as IL17 receptors, as well as fusion proteins including an IL17 receptor fused with a multimerization domain, and recombinant viral vectors encoding such fusions.
FILED	Thursday, April 17, 2014
APPL NO	14/785159
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1793 (20130101) Peptides C07K 14/7155 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2750/14143 (20130101)
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10640785 — Virus vectors for highly efficient transgene delivery

US 10640785	Mingozzi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S)	Federico Mingozzi (Paris, France); Xavier Anguela (Philadelphia, Pennsylvania); J. Fraser Wright (Princeton, New Jersey); Katherine A. High (Merion Station, Pennsylvania)
ABSTRACT	The invention provides viral vector formulations and methods of uses thereof for delivery of transgenes or therapeutic nucleic acids to human subjects. The formulations include a vector and suitable amounts of empty capsids, viral genome-containing capsids, or viral capsid proteins which are optionally chemically or structurally modified and which bind to neutralizing anti-AAV antibodies thereby reducing or preventing antibody-mediated clearance of the vector, but still allowing the genome-containing (therapeutic) vector to transduce target cells and achieve therapeutic gene transfer.
FILED	Wednesday, November 21, 2012
APPL NO	14/360151
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14123 (20130101) C12N 2750/14143 (20130101)
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10640789 — RNA-guided transcriptional regulation

US 10640789	Church et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	George M. Church (Brookline, Massachusetts); Prashant G. Mali (Somerville, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts)
ABSTRACT	Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.
FILED	Monday, February 22, 2016
APPL NO	15/049451
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/635 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3513 (20130101) Enzymes C12Y 301/00 (20130101)
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10640802 — AfArsR gene and prokaryotic host cell

US 10640802	Rosen
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Barry P. Rosen (Coral Gables, Florida)
ABSTRACT	Disclosed are methods of detecting organic arsenicals using genetically modified cells containing an arsR gene that encodes an AfArsR (As(III)-responsive repressor) protein and an arsenical resistance operon operably linked to a green fluorescent protein gene. The cell can produce a green fluorescent protein and fluoresce in the presence of trivalent organic arsenic. Trivalent organic arsenics can be one or more of phenylarsenite, travlent roaxarsone, and methylarsenite.
FILED	Thursday, May 03, 2018
APPL NO	15/970680
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class C12Q 1/18 (20130101) C12Q 1/689 (20130101) C12Q 2600/142 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101)
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10640810 — Methods of specifically labeling nucleic acids using CRISPR/Cas

US 10640810	Xiao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Drexel University (Philadelphia, Pennsylvania); The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania); Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania); The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania); Temple University (Philadelphia, Pennsylvania)
INVENTOR(S)	Ming Xiao (Huntingdon Valley, Pennsylvania); Harold C. Riethman (Chesapeake, Virginia); Wenhui Hu (Cherry Hill, New Jersey); Jennifer McCaffrey (Collegeville, Pennsylvania)
ABSTRACT	Provided herein are methods of detecting a target nucleic acid sequence. In one embodiment, the method includes contacting genomic DNA with a guide RNA having a portion complementary to the target sequence in the genomic DNA and with Cas9 nickase to produce a single-strand break in the genomic DNA at a specific location adjacent to the target sequence. The method further includes contacting the nicked DNA with a polymerase and fluorescently labeled nucleotide. The fluorescently labeled nucleotide is incorporated into the nicked DNA at the specific location and the target nucleic acid sequence is detected via fluorescent label.
FILED	Wednesday, October 18, 2017
APPL NO	15/787319
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 2521/301 (20130101) Enzymes C12Y 301/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/6428 (20130101) G01N 2021/6439 (20130101)
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10640820 — Methods relating to the detection of recurrent and non-specific double strand breaks in the genome

US 10640820	Alt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Frederick W. Alt (Cambridge, Massachusetts); Richard L. Frock (Jamaica Plain, Massachusetts); Jiazhi Hu (Boston, Massachusetts); Robin M. Meyers (Cambridge, Massachusetts)
ABSTRACT	Described herein are methods and systems relating to high throughput, genome-wide translocation sequencing (HTGTS) and/or detection of double-stranded DNA break (DSB) locations. The methods described herein can comprise generating DSBs in a nucleic acid sequence and performing nested PCR with the primers described herein. Described herein is an enhanced HTGTS approach. The assays and methods described herein permit the measurement of various DNA double-strand break (DSB) activities either intrinsic to the biological system or from outside agents.
FILED	Friday, November 20, 2015
APPL NO	15/527790
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2523/303 (20130101) C12Q 2523/303 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2549/119 (20130101) C12Q 2549/119 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201)
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10640826 — Spatial sequencing of nucleic acids using DNA origami probes

US 10640826	Church et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	George M. Church (Brookline, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Frederic Vigneault (Ashland, Massachusetts)
ABSTRACT	A method of sequencing nucleic acids is provided using DNA origami as a barcode for a nucleic acid probe.
FILED	Thursday, February 01, 2018
APPL NO	15/886163
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2533/107 (20130101) C12Q 2563/179 (20130101) C12Q 2563/185 (20130101)
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10641739 — Method and system for oblique backscattering ultrasound transmissive contrast imaging

US 10641739	Mertz
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Jerome Charles Mertz (Newton, Massachusetts)
ABSTRACT	An Oblique Backscatter Ultrasound imaging system includes a transceiver that has an US source and a plurality of US detectors configured in receive signals off axis from the US source. While the system is arranged in a reflective configuration, the device produces transmissive contrast signals to yield improved images. The transceiver can be mounted to a movable stage or robotic arm to enable it to scan the surface of a target. Alternatively, scanning can be performed by 1D or 2D phased-array transmission or detection.
FILED	Wednesday, December 23, 2015
APPL NO	15/538802
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/15 (20130101) A61B 8/48 (20130101) A61B 8/54 (20130101) A61B 8/4218 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5261 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0681 (20130101) Original (OR) Class G01N 2291/044 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52046 (20130101) G01S 7/52085 (20130101) G01S 15/8913 (20130101)
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10641854 — Systems and methods for automatic voxel positioning in magnetic resonance spectroscopy

US 10641854	Öz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Gülin Öz (Minneapolis, Minnesota); Christophe Lenglet (Shoreview, Minnesota); Young Woo Park (Seoul, South Korea)
ABSTRACT	Systems and methods for automated voxel positioning in magnetic resonance spectroscopy (“MRS”) are provided. In some aspects, a method includes receiving magnetic resonance (“MR”) imaging data acquired from a subject using an MR imaging system and registering the MR imaging data to an atlas having a pre-defined volume of interest (“VOI”), or segmenting a region of interest (“ROI”) directly from the MR data. The method also includes generating registration parameters based on the registration, and computing a transformed VOI using the pre-defined VOI in the atlas and the registration parameters. Alternatively, the VOI may be obtained by directly estimating it from the ROI.
FILED	Friday, December 01, 2017
APPL NO	15/829625
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4625 (20130101) G01R 33/4833 (20130101) Original (OR) Class G01R 33/5608 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101)
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10641857 — Methods for optimal gradient design and fast generic waveform switching

US 10641857	Overall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	HEARTVISTA, INC. (Los Altos, California)
ASSIGNEE(S)	HeartVista, Inc. (Los Altos, California)
INVENTOR(S)	William Overall (Los Altos, California); Juan Santos (Los Altos, California)
ABSTRACT	This disclosure provides a computer-implemented method for sequencing magnetic resonance imaging waveforms using a multistage sequencing hardware. The method comprises creating, with the aid of a computer processor, an active memory region that includes waveforms and schedules being played, and creating one or more buffer memory regions that contain waveforms and schedules not currently being played. Next, the waveforms and schedules in the one or more buffer memory regions may be updated while waveforms may be played in the active memory region. Upon completion of the waveform playback in the active memory region, the active and buffer memory regions may be swapped so that the former buffer memory region becomes the active memory region, and the former active memory region becomes the buffer memory region. The method may be repeated as needed until the imaging process is completed or otherwise halted.
FILED	Friday, March 06, 2015
APPL NO	14/640685
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/543 (20130101) G01R 33/561 (20130101) G01R 33/3852 (20130101) G01R 33/4822 (20130101) G01R 33/4824 (20130101) G01R 33/5608 (20130101) Original (OR) Class
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10642014 — Biodynamic microscopes and methods of use thereof

US 10642014	Nolte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	David D. Nolte (Lafayette, Indiana); John J. Turek (West Lafayette, Indiana); Ran An (West Lafayette, Indiana)
ABSTRACT	An apparatus for viewing a biological sample that functions as both a microscope and an interferometer. A short-coherence light source directs light onto the sample. A Fourier transform lens and a pixel-array detector are positioned to collect light scattered by the sample. An optic fiber assembly conveys a reference beam from the short-coherence light source. The detector collects the reference beam and the signal beam and uses coherence gating to acquire interferometric image data. In some embodiments the axis of the incident light striking the sample and the axis of collected scattered signal light form an angle of less than 180 degrees and advantageously an angle between 120 and 150 degrees. A method of converting a microscope into an interferometer is also disclosed.
FILED	Friday, March 11, 2016
APPL NO	15/068275
ART UNIT	2488 — Recording and Compression
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/2804 (20130101) G02B 21/14 (20130101) G02B 21/24 (20130101) G02B 21/086 (20130101) G02B 21/0088 (20130101) Original (OR) Class G02B 21/365 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/212 (20130101) Holographic Processes or Apparatus G03H 1/0443 (20130101) G03H 1/0465 (20130101) G03H 2001/005 (20130101) G03H 2001/0445 (20130101) G03H 2001/0467 (20130101) G03H 2222/24 (20130101)
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10642019 — Method and apparatus for imaging unsectioned tissue specimens

US 10642019	Fujimoto et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	James G. Fujimoto (Cambridge, Massachusetts); Michael G. Giacomelli (Cambridge, Massachusetts); Tadayuki Yoshitake (Cambridge, Massachusetts); Lucas C. Cahill (Cambridge, Massachusetts)
ABSTRACT	An apparatus and method for real-time optical imaging of a tissue specimen. The apparatus comprises a primary imaging system configured to use an illumination source to acquire images of a tissue specimen through one or more spectrally separated channels, and configured to perform optical depth sectioning; an auxiliary imaging system, configured to acquire an auxiliary image of the tissue specimen; a specimen holder having a transparent window therewithin, window, the specimen holder comprising one or more position sensors, wherein the specimen holder is configured to be translatable in the specimen plane; a user input device configured to accept user input, wherein the specimen holder is configured to translate in response to the user input in real-time; a processing unit configured to execute a sequence of instructions on the sequence of images acquired by the primary imaging system, the auxiliary image, and at least one specimen holder position to generate a composite representation of the tissue specimen that includes a representation of cell nuclei in the specimen; and a display device configured to display the composite representation of the tissue specimen in real-time.
FILED	Monday, August 05, 2019
APPL NO	16/531714
ART UNIT	2488 — Recording and Compression
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/0106 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/26 (20130101) G02B 21/086 (20130101) G02B 21/0088 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class
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10642027 — 3D MEMS scanner for real-time cross-sectional endomicroscopy

US 10642027	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Thomas D. Wang (Ann Arbor, Michigan); Haijun Li (Ann Arbor, Michigan); Xiyu Duan (Ann Arbor, Michigan); Zhen Qiu (Menlo Park, California); Kenn Oldham (Ann Arbor, Michigan)
ABSTRACT	An optical probe scanning assembly for use in an optical probe includes a mirror assembly that focuses an illumination beam path and a collection beam path at a region of interest within the sample. The illumination beam and the collection beam overlap to form a confocal beam region. The mirror assembly is movable in an x-axis direction and in a y-axis direction to scan the confocal beam region within the sample. The scanning assembly further includes a scanning suspension system including a gimbal assembly connected to the mirror assembly to allow the mirror assembly to rotate about one or more axes. The mirror is thereby adapted to scan along at least two different orthogonal planes, one of which extends vertically into the sample.
FILED	Thursday, December 08, 2016
APPL NO	15/781065
ART UNIT	2872 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/313 (20130101) A61B 5/0068 (20130101) A61B 5/0073 (20130101) A61B 5/1459 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Optical Elements, Systems, or Apparatus G02B 6/26 (20130101) G02B 21/0048 (20130101) G02B 23/24 (20130101) G02B 26/103 (20130101) G02B 26/0841 (20130101) Original (OR) Class
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10643354 — Automatic system calibration method of X-ray CT

US 10643354	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)	Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S)	Ge Wang (Loudonville, New York); Mianyi Chen (Troy, New York); Yan Xi (Syracuse, New York); Wenxiang Cong (Albany, New York)
ABSTRACT	Systems and methods for geometric calibration and image reconstruction in computed tomography (CT) scanning using iterative reconstruction algorithms are provided. An iterative reconstruction algorithm can be used to reconstruct an improved image, and then the improved image can be used to adjust inaccurate parameters by using a Locally Linear Embedding (LLE) method. Adjusted parameters can then be used to reconstruct new images, which can then be used to further adjust the parameters. The steps of this iterative process can be repeated until a quality threshold is met.
FILED	Monday, March 21, 2016
APPL NO	15/558053
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/582 (20130101) A61B 6/5205 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class G06T 11/006 (20130101) G06T 2207/20 (20130101) G06T 2207/10116 (20130101) G06T 2211/412 (20130101) G06T 2211/424 (20130101)
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10643396 — Methods and software for creating a 3D image from images of multiple histological sections and for mapping anatomical information from a reference atlas to a histological image

US 10643396	Eastwood et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Microbrightfield, Inc. (Williston, Vermont)
ASSIGNEE(S)	Microbrightfield, Inc. (Williston, Vermont)
INVENTOR(S)	Brian S. Eastwood (Northampton, Massachusetts); Susan Tappan (Hinesburg, Vermont); Nathan J. O'Connor (Essex Junction, Vermont)
ABSTRACT	Methods and software assisting a user in working with images of histological sections to increase the user's productivity and decrease the need for extensive expertise in anatomy. In some embodiments, the methods include methods of assisting a user in creating a 3D volume image of a tissue block from a series of images of histological sections taken from the tissue block. In some embodiments, the methods include methods of automatedly registering a live-view or stored histological section image to a tissue block atlas. In some embodiments, the methods include methods of annotating a histological section image with information from a tissue block atlas based on user input(s) associated with the tissue block atlas. In some embodiments, the methods include methods of automatedly controlling operation of an imaging modality, such as an optical microscope, based on user input(s) associated with a tissue block atlas. These and other methods may be embodied in various configurations of software.
FILED	Monday, November 13, 2017
APPL NO	15/811039
ART UNIT	2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/194 (20170101) G06T 15/08 (20130101) G06T 19/006 (20130101) G06T 19/20 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10056 (20130101) G06T 2207/20104 (20130101) G06T 2207/20108 (20130101) G06T 2207/20128 (20130101) G06T 2207/20212 (20130101) G06T 2207/30024 (20130101) G06T 2207/30168 (20130101) G06T 2219/004 (20130101) G06T 2219/028 (20130101) G06T 2219/2004 (20130101)
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10643832 — Collection probe and methods for the use thereof

US 10643832	Eberlin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Livia Schiavinato Eberlin (Austin, Texas); Thomas Milner (Austin, Texas); Jialing Zhang (Austin, Texas); John Lin (Austin, Texas); John Rector (Austin, Texas); Nitesh Katta (Austin, Texas); Aydin Zahedivash (Austin, Texas)
ABSTRACT	Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
FILED	Thursday, August 31, 2017
APPL NO	15/692167
ART UNIT	2881 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 10/0045 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502 (20130101) B01L 2200/0605 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 30/72 (20130101) G01N 33/487 (20130101) G01N 33/574 (20130101) G01N 33/6848 (20130101) G01N 2001/028 (20130101) G01N 2001/4061 (20130101) G01N 2560/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/0031 (20130101) H01J 49/0431 (20130101) Original (OR) Class
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RE047972 — Preparation and composition of inter-alpha inhibitor proteins from human plasma for therapeutic use

US RE47972	Lim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Pro Thera Biologics, Inc. (Providence, Rhode Island)
ASSIGNEE(S)	ProThera Biologics, Inc. (Providence, Rhode Island)
INVENTOR(S)	Yow-Pin Lim (Providence, Rhode Island); Djuro Josic (Houston, Texas); Douglas C. Hixson (Boulder, Colorado)
ABSTRACT	The invention relates to Inter-alpha inhibitor proteins (IαIp). The invention further relates to processes for purification of IαIp compositions and their use for treatment of human diseases such as sepsis and septic shock, rheumatoid arthritis, cancer and infectious diseases.
FILED	Friday, April 26, 2013
APPL NO	13/871500
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Separation B01D 15/363 (20130101) B01D 15/363 (20130101) B01D 15/3804 (20130101) B01D 15/3804 (20130101) Peptides C07K 14/811 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/96 (20130101) G01N 33/566 (20130101) G01N 2030/009 (20130101) G01N 2333/81 (20130101) G01N 2800/52 (20130101)
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Department of Energy (DOE)

10639591 — Thin-film composite membrane and processes for the separation of alkenes from a gaseous feed mixture

US 10639591	Lousenberg et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Compact Membrane Systems, Inc. (Newport, Delaware)
ASSIGNEE(S)	COMPACT MEMBRANE SYSTEMS, INC. (Newport, Delaware)
INVENTOR(S)	Robert Daniel Lousenberg (Wilmington, Delaware); Kenneth Evan Loprete (Philadelphia, Pennsylvania)
ABSTRACT	This invention discloses an improved thin-film composite membrane and processes that use the membrane for the separation of gaseous mixtures that include an alkene. The membrane is particularly useful for separation of alkenes from alkanes or the separation of alkenes from other non-hydrocarbon gases. The membrane has a more mechanically durable and defect-free gas-separation layer that is fabricated from an ionomer solution that is substantially free of dissolved ionic species not associated with the ionomer and the mean helium permeability of the thin-film composite membrane is less than two times greater than the intrinsic helium permeability of the gas-separation layer.
FILED	Thursday, April 11, 2019
APPL NO	16/381333
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/36 (20130101) B01D 71/82 (20130101) B01D 2257/702 (20130101) B01D 2323/08 (20130101) B01D 2323/30 (20130101) B01D 2325/04 (20130101) B01D 2325/20 (20130101)
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10639704 — Self-aligning swaging punch and method for swaging

US 10639704	Branson et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Donald Conrad Branson (Kansas City, Missouri); Kevin Troyer (Kansas City, Missouri)
ABSTRACT	A self-aligning swaging punch is provided for adjoining together a pin and a workpiece having a pinhole. The swaging punch comprises a shaft and a tip having an open-ended cavity. The shaft transfers an axial force from a press or hammer to the tip. The tip transfers the axial force from the shaft to a top surface of the workpiece near the pinhole. The tip may be spherical in shape for evenly deforming the workpiece near the upper edge of the pinhole. The open-ended cavity receives the pin therein and allows the pin to extend at least partially into the open-ended cavity while the tip contacts the workpiece. The open-ended cavity also ensures that the swaging punch is aligned with the pinhole and perpendicular to the surface of the workpiece when the pin is inserted into the pinhole such that the workpiece evenly deforms and presses against the pin.
FILED	Thursday, September 27, 2018
APPL NO	16/144603
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 28/34 (20130101) B21D 39/06 (20130101) Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/02 (20130101) B21J 15/10 (20130101) B21J 15/36 (20130101) B21J 15/105 (20130101) Making Forged or Pressed Metal Products, e.g Horse-shoes, Rivets, Bolts or Wheels B21K 25/00 (20130101) Original (OR) Class Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 11/00 (20130101) Perforating; Punching; Cutting-out; Stamping-out; Severing by Means Other Than Cutting B26F 1/14 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49908 (20150115) Y10T 29/49913 (20150115) Y10T 29/49917 (20150115) Y10T 29/49925 (20150115) Y10T 29/49934 (20150115) Y10T 29/49936 (20150115) Y10T 29/49945 (20150115)
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10639719 — Grain boundary engineering for additive manufacturing

US 10639719	Lou et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Niskayuna, New York)
INVENTOR(S)	Xiaoyuan Lou (Rexford, New York); Evan Jarrett Dolley (Clifton Park, New York); Martin Matthew Morra (Schenectady, New York)
ABSTRACT	In one embodiment, a method of manufacturing a metal part using a laser or electron beam during a powder bed additive manufacturing process includes melting each of a number of layers of metal powder of the metal part with an effective amount of energy using the laser or electron beam to form the metal part such that at least one or more portions of the metal part have a critical amount of residual strain. The method also includes performing a heat treatment on the metal part that transforms the residual strain into substantially distributed coincidence site lattice (CSL) grain boundaries, low angle grain boundaries, or both in the metal part.
FILED	Wednesday, September 28, 2016
APPL NO	15/279182
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/24 (20130101) Original (OR) Class B22F 3/1055 (20130101) B22F 2003/248 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/34 (20130101) C21D 2201/05 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101)
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10640395 — Functionalized surfaces for the destruction of pathogens and organics

US 10640395	Stewart et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Thomas Austin Stewart (Albuquerque, New Mexico); May D. Nyman (Corvallis, Oregon)
ABSTRACT	The disclosure is directed to a surface having a binding component applied thereto for the adsorption or capture of pathogens and organic molecules or materials. The surface may be a component of a porous or nonporous substrate. The binding component may also bind a photocatalyst to the surface for photocatalytic destruction of the captured pathogens and organic molecules or materials.
FILED	Tuesday, October 23, 2018
APPL NO	16/168501
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 67/0088 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/145 (20130101) B01D 2257/91 (20130101) B01D 2325/14 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/0211 (20130101) B01J 20/3204 (20130101) B01J 20/3219 (20130101) B01J 20/3242 (20130101) B01J 20/3248 (20130101) B01J 20/3285 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) Original (OR) Class C02F 1/288 (20130101) C02F 2303/04 (20130101) C02F 2305/10 (20130101)
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10640435 — Multimetallic catalysts

US 10640435	Stair et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Peter C. Stair (Northbrook, Illinois); Jeffrey Camacho Bunquin (Westmont, Illinois); Christopher L. Marshall (Naperville, Illinois); Adam S. Hock (Chicago, Illinois)
ABSTRACT	A multimetallic catalyst having a substrate, intermediate layer and catalyst layer. The catalyst exhibits selectivity greater than 90% and a conversion rate of greater than 30%.
FILED	Tuesday, May 17, 2016
APPL NO	15/157109
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/60 (20130101) B01J 23/8926 (20130101) B01J 37/0244 (20130101) Acyclic or Carbocyclic Compounds C07C 5/3337 (20130101) Original (OR) Class C07C 5/3337 (20130101) C07C 11/06 (20130101) C07C 2521/08 (20130101) C07C 2523/06 (20130101) C07C 2523/34 (20130101) C07C 2523/42 (20130101) C07C 2523/60 (20130101) C07C 2523/656 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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10640537 — Host cells and methods using a repressor polypeptide and an inducible promoter for gene expression

US 10640537	Ruegg
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Thomas L. Ruegg (Berkeley, California)
ABSTRACT	The present invention provides for a system comprising (a) a first nucleic acid comprising a nucleotide sequence encoding a nucleotide sequence of interest operatively linked to a promoter comprising a repressor polypeptide binding site, and (b) a second nucleic acid comprising a nucleotide sequence encoding a repressor polypeptide having at least 70% amino acid identity with EilR, SmvR, KmrR, RcdA, or QacR; wherein expression of the nucleotide sequence of interest from the promoter is induced by the presence of a hydrophobic inducer, such as a hydrophobic cation inducer, such as a triarylmethane, acridine, phenazine, phenothiazine, or xanthene.
FILED	Friday, July 01, 2016
APPL NO	15/201248
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/245 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101)
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10640746 — Synthetic methylotrophs

US 10640746	Papoutsakis et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	UNIVERSITY OF DELAWARE (Newark, Delaware)
ASSIGNEE(S)	University of Delaware (Newark, Delaware)
INVENTOR(S)	Eleftherios T. Papoutsakis (Newark, Delaware); William Brian Whitaker (Wilmington, Delaware); Robert Kyle Bennett (Elkton, Maryland)
ABSTRACT	The present invention provides a non-naturally occurring microbe capable of growing in a medium comprising methanol, comprising a heterologous polynucleotide encoding a heterologous methanol dehydrogenase (MDH) derived from a Corynebacterium organism (Cor), wherein the MDH is expressed in the microbe, and wherein the MDH exhibits a Km of no more than 3 mM for methanol. Also provided are uses of the non-naturally occurring microbe for oxidizing methanol and producing a metabolite as well as the preparation of the non-naturally occurring microbe.
FILED	Friday, January 13, 2017
APPL NO	16/070318
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/32 (20130101) Original (OR) Class C12N 9/0006 (20130101) C12N 15/52 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/15 (20130101) C12R 1/19 (20130101) Enzymes C12Y 101/01244 (20130101)
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10640789 — RNA-guided transcriptional regulation

US 10640789	Church et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	George M. Church (Brookline, Massachusetts); Prashant G. Mali (Somerville, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts)
ABSTRACT	Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.
FILED	Monday, February 22, 2016
APPL NO	15/049451
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/635 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3513 (20130101) Enzymes C12Y 301/00 (20130101)
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10640858 — Methods for preparing superalloy articles and related articles

US 10640858	Detor et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Andrew Joseph Detor (Albany, New York); Richard DiDomizio (Charlton, New York); Timothy Hanlon (Town Glenmont, New York); Chen Shen (Schenectady, New York); Ning Zhou (Clifton Park, New York)
ABSTRACT	A method for preparing an improved article including a nickel-based superalloy is presented. The method includes heat-treating a workpiece including a nickel-based superalloy at a temperature above the gamma-prime solvus temperature of the nickel-based superalloy and cooling the heat-treated workpiece with a cooling rate less than 50 degrees Fahrenheit/minute from the temperature above the gamma-prime solvus temperature of the nickel-based superalloy so as to obtain a cooled workpiece. The cooled workpiece includes a coprecipitate of a gamma-prime phase and a gamma-double-prime phase, wherein the gamma-prime phase of the coprecipitate has an average particle size less than 250 nanometers. An article having a minimum dimension greater than 6 inches is also presented. The article includes a material having a coprecipitate of a gamma-prime phase and a gamma-double-prime phase, wherein the gamma-prime phase of the coprecipitate has an average particle size less than 250 nanometers.
FILED	Thursday, June 30, 2016
APPL NO	15/198658
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Alloys C22C 19/03 (20130101) C22C 19/05 (20130101) C22C 19/055 (20130101) C22C 19/056 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Original (OR) Class
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10640954 — Sorption-based atmospheric water harvesting device

US 10640954	Kim et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S)	Hyunho Kim (Cambridge, Massachusetts); Sungwoo Yang (Cambridge, Massachusetts); Shankar Narayanan (Colonie, New York); Ari Samuel Umans (Belmont, Massachusetts); Evelyn N. Wang (Cambridge, Massachusetts); Sameer R. Rao (Cambridge, Massachusetts)
ABSTRACT	A water-harvesting system can operate with a material that can take up and release water with minimum energy requirements and powered by low-grade energy sources, such as sunlight, in order to potentially allow its deployment into households, especially those located in sunny regions. A water-harvesting method and system can include vapor adsorption using a porous metal-organic framework. In certain embodiments, the porous metal-organic framework can include metal-organic framework in ambient air with low relative humidity, typical of the levels found in most dry regions of the world.
FILED	Thursday, November 30, 2017
APPL NO	15/828397
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 5/0003 (20130101) B01D 5/006 (20130101) B01D 5/0015 (20130101) B01D 15/36 (20130101) B01D 53/261 (20130101) B01D 2253/204 (20130101) B01D 2257/80 (20130101) B01D 2258/06 (20130101) B01D 2259/80 (20130101) B01D 2259/40098 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/103 (20130101) B01J 20/226 (20130101) B01J 20/324 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/3238 (20130101) B01J 20/28047 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/288 (20130101) C02F 2201/001 (20130101) C02F 2201/32 (20130101) Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 3/28 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 20/109 (20180101)
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10641175 — Panel fuel injector

US 10641175	Berry et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenecady, New York)
INVENTOR(S)	Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (Pittsburgh, Pennsylvania)
ABSTRACT	The present disclosure is directed to a panel fuel injector having a first side wall that defines a plurality of first side injection outlets and a second side wall that defines a plurality of second side injection outlets. A premix air plenum, a fuel plenum, a plurality of first side premixing channels and a plurality of second side premixing channels are defined between the first side wall and the second side wall. Each first side premixing channel is in fluid communication with the premix air plenum, the fuel plenum and a respective first side injection outlet of the plurality of first side injection outlets. Each second side premixing channel is in fluid communication with the premix air plenum, the fuel plenum and a respective second side injection outlet of the plurality of second side injection outlets.
FILED	Friday, February 24, 2017
APPL NO	15/442227
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/22 (20130101) F02C 7/222 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/005 (20130101) F23R 3/06 (20130101) F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/34 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101)
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10641176 — Combustion system with panel fuel injector

US 10641176	Berry et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (Pittsburgh, Pennsylvania)
ABSTRACT	The present disclosure is directed to an annular combustion system. The annular combustion system includes an inner liner and an outer liner that define therebetween an annulus that circumscribes a centerline of the combustion system. The annulus includes a plurality of primary combustion zones defined at an upstream end thereof and further defines a plurality of secondary combustion zones downstream of the primary combustion zones. The annular combustion system further includes a plurality of fuel nozzles where at least one fuel nozzle discharges a combustible mixture into a respective primary combustion zone of the plurality of primary combustion zones. A plurality of panel fuel injectors is disposed between adjacent fuel nozzles. The plurality of panel fuel injectors extends in an axially downstream direction so as to separate adjacent primary combustion zones. Each panel fuel injector discharges a combustible mixture into at least one secondary combustion zone.
FILED	Friday, February 24, 2017
APPL NO	15/442255
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/22 (20130101) F02C 7/222 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/005 (20130101) F23R 3/06 (20130101) F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/34 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101)
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10641177 — Apparatus and process of retrofitting a combined cycle power plant

US 10641177	Brostmeyer et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Joseph D. Brostmeyer (Jupiter, Florida); Russell B. Jones (North Palm Beach, Florida); Justin T. Cejka (Palm Beach Gardens, Florida); John A. Orosa (Palm Beach Gardens, Florida); John E. Ryznic (Jupiter, Florida)
ABSTRACT	A process for retrofitting an electric power plant that uses two 60 Hertz large frame heavy duty industrial gas turbine engines to drive electric generators and produce electricity, where each of the two industrial engines can produce up to 350 MW of output power. The process replaces the two 350 MW industrial engines with one twin spool industrial gas turbine engine that is capable of producing at least 700 MW of output power. Thus, two prior art industrial engines can be replaced with one industrial engine that can produce power equal to the two prior art industrial engines.
FILED	Wednesday, March 23, 2016
APPL NO	15/549050
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 25/08 (20130101) F01D 25/12 (20130101) Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 23/10 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) F02C 3/13 (20130101) F02C 6/08 (20130101) F02C 6/18 (20130101) F02C 7/185 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/76 (20130101) F05D 2230/80 (20130101) F05D 2260/211 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/16 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101)
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10641491 — Cooling of integrated combustor nozzle of segmented annular combustion system

US 10641491	Berry et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Jonathan Dwight Berry (Simpsonville, South Carolina); Stanley Kevin Widener (Greenville, South Carolina); Michael John Hughes (State College, Pennsylvania)
ABSTRACT	A segmented annular combustion system includes integrated combustor nozzles, each of which has a fuel injection panel disposed radially between an inner liner segment and an outer liner segment. The fuel injection panel includes an aft end portion, a first side wall, a second side wall, premixing channels defined between the first side wall and the side wall, and injection outlets defined along at least one of the first side wall and the second side wall. The aft end portion defines a turbine nozzle portion. An interior portion between the first side wall and the second side wall includes walls that extend between the first and second side walls, thereby partitioning the interior portion into discrete air cavities. The air cavities and the liner segments may be cooled by impingement inserts or panels.
FILED	Tuesday, March 21, 2017
APPL NO	15/464425
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/286 (20130101) F23R 3/346 (20130101) F23R 2900/03044 (20130101)
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10641524 — High temperature synthesis for power production and storage

US 10641524	Lavine et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Adrienne Gail Lavine (Sherman Oaks, California); Richard Edward Wirz (Los Angeles, California); Hamarz Aryafar (Los Angeles, California); Chen Chen (Los Angeles, California); Keith Lovegrove (O'Connor, Australia)
ABSTRACT	Thermochemical energy storage (TCES) for concentrating solar power (CSP) systems provides higher energy density than sensible energy storage systems. An ammonia-based TCES system dissociates endothermically into hydrogen and nitrogen. The stored energy is released when supercritical hydrogen and nitrogen react exothermically to synthesize ammonia. Prior ammonia synthesis systems are unable to produce temperatures consistent with modern power blocks requiring a working fluid, for example steam or carbon dioxide, to be heated to greater than 600° C., for example about 650° C. An ammonia synthesis system heats steam from, for example 350° C. to 650° C. under pressure of about 26 MPa. The hydrogen and nitrogen are preheated with a flow of supercritical fluid prior to the synthesis step to provide reaction rates sufficient to heat power block working fluid to the desired temperature.
FILED	Monday, June 27, 2016
APPL NO	15/739125
ART UNIT	3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 5/00 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 45/04 (20130101) F04B 45/043 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) F24S 23/71 (20180501) F24S 23/74 (20180501) F24S 60/00 (20180501) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/003 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 10/45 (20130101) Y02E 60/142 (20130101) Y02E 70/30 (20130101)
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10641572 — Microwave ignition of energetic material housed within a gun

US 10641572	Perry et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	William Lee Perry (Los Alamos, New Mexico); Amanda Lynn Duque (Los Alamos, New Mexico)
ABSTRACT	The systems and methods for microwave ignition of energetic material housed within a gun (e.g., primers and/or propellants) allow for the use of insensitive energetic materials and/or insensitive gas-generating materials in place of sensitive energetic materials relied upon by mechanical ignition systems. In some embodiments, the use of insensitive energetic materials and/or insensitive gas-generating materials increase the safety and reliability of guns that would otherwise need to depend on sensitive energetic material required by mechanical or laser ignition mechanisms. Additionally, in some embodiments, the systems and methods provide greater versatility with respect to the variety of energetic materials that may be employed within guns.
FILED	Wednesday, April 19, 2017
APPL NO	15/491314
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 19/58 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/08 (20130101)
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10641651 — Ultrasonic microphone and ultrasonic acoustic radio

US 10641651	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises 5 a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range
FILED	Wednesday, February 24, 2016
APPL NO	15/558467
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101)
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10641733 — Active mechanical-environmental-thermal MEMS device for nanoscale characterization

US 10641733	Jungjohann et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Katherine L. Jungjohann (Albuquerque, New Mexico); William Mook (Albuquerque, New Mexico); Claire Chisholm (Albuquerque, New Mexico); Michael Shaw (Tijeras, New Mexico); Khalid M. Hattar (Albuquerque, New Mexico); Paul C. Galambos (Albuquerque, New Mexico); Andrew Jay Leenheer (Albuquerque, New Mexico); Sean J. Hearne (Albuquerque, New Mexico)
ABSTRACT	A microelectromechanical system (MEMS) device can be used for quantitative mechanical testing of materials within a controlled (chemical and temperature) environment, with the ability for electrochemical control to the specimen, that is coupled with a complimentary in-situ characterization technique.
FILED	Monday, March 19, 2018
APPL NO	15/925118
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/02 (20130101) G01N 3/08 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 30/6095 (20130101) G01N 2203/0017 (20130101) G01N 2203/0286 (20130101)
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10641840 — Systems, methods and patches for monitoring a structural health of a connector in overhead transmission lines

US 10641840	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Hong Wang (Oak Ridge, Tennessee); Jy-An Wang (Oak Ridge, Tennessee); Fei Ren (Philadelphia, Pennsylvania)
ABSTRACT	Systems, methods and piezoelectric patches are provided for monitoring the structural health of connectors in overhead transmission lines. A plurality of piezoelectric patches is mounted to different locations on the connector. At least one of the patches is actuated using an AC voltage and certain electrical properties either from the same patch or of a different patch are evaluated over time to determine the structural health of the connectors.
FILED	Thursday, January 25, 2018
APPL NO	15/880081
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 29/22 (20130101) G01R 31/66 (20200101) Original (OR) Class G01R 31/085 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) H01L 41/042 (20130101) H01L 41/047 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/6683 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 7/00 (20130101) Transmission H04B 3/54 (20130101)
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10641912 — “4H” X-ray camera

US 10641912	Wang
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Zhehui Wang (Los Alamos, New Mexico)
ABSTRACT	A 4H X-ray camera includes a high speed, high atomic number (Z), high spatial resolution sensor for sensing X-rays having energy over 30 keV and high speed readout electronics, and the high speed, high atomic number (Z), high spatial resolution sensor is coupled to the high speed readout electronics.
FILED	Wednesday, June 14, 2017
APPL NO	15/622557
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 1/247 (20130101) G01T 1/2928 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0304 (20130101)
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10642123 — Self-powered and reversible light-directed electrophoretic deposition device for use in smart windows and photodetector displays

US 10642123	Mora et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Jeronimo Mora (Oakland, California); Brian Giera (Oakland, California); Jessica Katheryn Dudoff (Northglenn, Colorado); Elaine Lee (Brooklyn, New York)
ABSTRACT	According to one embodiment, a method includes receiving light on a photoconductive layer of an electrophoretic deposition (EPD) device, the EPD device having a chamber defined by a first sheet, a second sheet and a spacer between the first and second sheets, where the first sheet is nonopaque and includes the photoconductive layer, where the second sheet is nonopaque and spaced from the first sheet, where a fluidic solution having a plurality of particles is in the chamber. The particles in the solution are attracted from suspension to illuminated portions of the photoconductive layer in the absence of an external voltage applied to the first and second sheets. The particles become deposited on the illuminated portions of the photoconductive layer.
FILED	Monday, June 24, 2019
APPL NO	16/450773
ART UNIT	2872 — Optics
CURRENT CPC	Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/02 (20130101) C25D 13/22 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) E06B 2009/2464 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/167 (20130101) Original (OR) Class G02F 1/1354 (20130101) G02F 1/13394 (20130101)
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10642253 — System, method, and computer program for creating geometry-compliant lattice structures

US 10642253	Vernon
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Gregory John Vernon (Kansas City, Missouri)
ABSTRACT	A system and method of creating a shape-conforming lattice structure for a part formed via additive manufacturing. The method includes receiving a computer model of the part and generating a finite element mesh. A lattice structure including a number of lattice cellular components may also be generated. Some of the mesh elements of the finite element mesh may be deformed so that the finite element mesh conforms to the overall shape of the part. The lattice structure may then be deformed so that the lattice structure has a cellular periodicity corresponding to the finite elements of the finite element mesh. In this way, the part retains the benefits of its overall shape and the benefits of lattice features without introducing structural weak points, directional stresses, and other structural deficiencies.
FILED	Wednesday, March 27, 2019
APPL NO	16/366690
ART UNIT	2892 — Semiconductors/Memory
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/265 (20151101)
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10643031 — System and method of content based recommendation using hypernym expansion

US 10643031	Potok et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Thomas E. Potok (Oak Ridge, Tennessee); Robert M. Patton (Knoxville, Tennessee); Sreenivas R. Sukumar (Oak Ridge, Tennessee)
ABSTRACT	A system and method for document recommendation combines linguistic and term frequency approaches in order to improve overall performance and recommendation. Hypernyms are added to the source document set so that related documents can be recommended from the source document set. There are a variety of different parameters to configure that change operation of the document recommendation system.
FILED	Friday, March 10, 2017
APPL NO	15/455260
ART UNIT	2168 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/3338 (20190101) G06F 16/3347 (20190101) G06F 19/30 (20130101) G06F 40/30 (20200101) Original (OR) Class G06F 40/242 (20200101)
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10643156 — Precision snow removal analysis

US 10643156	Omitaomu et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Olufemi A. Omitaomu (Knoxville, Tennessee); Budhendra L. Bhaduri (Knoxville, Tennessee)
ABSTRACT	A method for precision snow removal analysis provides a melt rate in inches per day for roadways in a geometric region is provided. Elevation data is used to calculate upward looking hemispherical viewsheds at each roadway coordinate to determine the total solar radiation. The snowmelt capacity and slope are determined at each coordinate and the data is displayed on a geographical map of the roadway. The processing speed of the computer is improved since the snowmelt capacity is only determined for a roadway subset of the region coordinates.
FILED	Wednesday, March 15, 2017
APPL NO	15/459036
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) G01S 17/95 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 99/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/063 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 90/19 (20180101)
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10643756 — Mobile heat pipe cooled fast reactor system

US 10643756	McClure et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Patrick Ray McClure (Los Alamos, New Mexico); David Duff Dixon (Elder, South Dakota); David Irvin Poston (Los Alamos, New Mexico); Richard J. Kapernick (Los Alamos, New Mexico); Robert Stowers Reid (Los Alamos, New Mexico); Venkateswara Rao Dasari (Los Alamos, New Mexico)
ABSTRACT	A mobile heat pipe cooled fast nuclear reactor may be configured for transportation to remote locations and may be able to provide 0.5 to 2 megawatts of power. The mobile heat pipe cooled fast reactor may contain a plurality of heat pipes that are proximate to a plurality of fuel pins inside the reactor. The plurality of heat pipes may extend out of the reactor. The reactor may be configured to be placed in a standard shipping container, and may further be configured to be contained within a cask and attached to a skid for easier transportation.
FILED	Tuesday, April 15, 2014
APPL NO	14/773405
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Nuclear Reactors G21C 1/02 (20130101) G21C 15/257 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/34 (20130101)
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10643776 — System and method for the recycling of rare earth magnets

US 10643776	McIntyre
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Timothy J. McIntyre (Farragut, Tennessee)
ABSTRACT	A system and a method for separating and recycling magnets made from rare earth elements from an article of manufacture used an alignment device to property position the rare earth magnet for processing. Once proper alignment is made, a separating device removes the magnet and a portion of the article. A heating device demagnetizes the magnets and vibration causes the magnets to separate from the portion of the article. Electromagnets remove the portion of the article and the rare earth magnets pass through for reclamation.
FILED	Wednesday, November 02, 2016
APPL NO	15/341057
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/26 (20130101) B03C 1/0335 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 13/006 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/103 (20130101) H05B 2206/023 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/24 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/541 (20150501)
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10645793 — Automatic tuning of dressed multicell cavities using pressurized balloons

US 10645793	Hassan et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Fermi National Accelerator Laboratory (FNAL) Federally Funded Research and Development Center (FFRDC) Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S)	Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S)	FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
INVENTOR(S)	Mohamed Awida Hassan (Aurora, Illinois); Donato Passarelli (Aurora, Illinois)
ABSTRACT	A method and system for automatically tuning hollow structures, can include pressurized balloons located in one or more targeted cells of a hollow structure of a device having a hollow structures and respective cells. A pressurized balloon can be inserted into a targeted cell so as to localize plastic deformation to the targeted cell using prescribed values of global force and balloon pressure. A pair of inflate/deflate rods associated with an independent air supply for the pressurized balloon can inflate or deflate the pressurized balloon without affecting other pressurized balloons. The pair of inflate/deflate rods can be automatically insertable or removable from the hollow structure by controlled motorized motions.
FILED	Saturday, October 26, 2019
APPL NO	16/664843
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) Original (OR) Class
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10645842 — Cold plate with combined inclined impingement and ribbed channels

US 10645842	Parida
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Pritish R. Parida (Fishkill, New York)
ABSTRACT	Heat transfer devices and methods for making the same that include a first enclosure having at least one inlet port; a second enclosure having a bottom plate and one or more dividing walls to establish channels, at least one internal surface of each channel having rib structures to create turbulence in a fluid flow; and a jet plate connecting the first enclosure and the second enclosure having impinging jets that convey fluid from the first enclosure to the channels, said impinging jets being set at an angular deviation from normal to cause local acceleration of fluid and to increase a local heat transfer rate.
FILED	Wednesday, September 23, 2015
APPL NO	14/862793
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 3/048 (20130101) F28F 13/02 (20130101) F28F 2215/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/467 (20130101) H01L 23/4735 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20218 (20130101) H05K 7/20254 (20130101) Original (OR) Class H05K 7/20263 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4935 (20150115) Y10T 29/49359 (20150115)
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National Science Foundation (NSF)

10639363 — Cancer immunotherapy using virus particles

US 10639363	Steinmetz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN REVERSE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Nicole F. Steinmetz (Cleveland, Ohio); Amy M. Wen (Cleveland, Ohio); Steven Fiering (Cleveland, Ohio); Patrick H. Lizotte (Cleveland, Ohio)
ABSTRACT	A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
FILED	Monday, May 08, 2017
APPL NO	15/589677
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/544 (20130101) A61K 2039/585 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/00023 (20130101) C12N 2770/00034 (20130101) C12N 2770/00071 (20130101) C12N 2770/32022 (20130101) C12N 2770/32023 (20130101) C12N 2770/32034 (20130101) C12N 2770/32071 (20130101)
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10639371 — Thermoresponsive bioconjugates and their controlled delivery of cargo

US 10639371	Kiick et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Kristi Kiick (Rising Sun, Maryland); Tianzhi Luo (Newark, Delaware)
ASSIGNEE(S)	University of Delaware (Newark, Delaware)
INVENTOR(S)	Kristi Kiick (Rising Sun, Maryland); Tianzhi Luo (Newark, Delaware)
ABSTRACT	The present invention provides a bioconjugate. The bioconjugate comprises a first molecule comprising an elastin-like peptide (ELP), a second molecule capable of self-associating into an oligomer, and a linker connecting the first molecule with the second molecule. The bioconjugate is self-assembled into particles, which are disassembled when the temperature is increased. Also provided is a method for delivering a bioconjugate to a target matrix, comprising (a) introducing a bioconjugate self-assembled into particles to a target matrix, wherein the bioconjugate comprises a first molecule comprising an elastin-like peptide (ELP), a second molecule capable of self-associating into an oligomer, and a linker connecting the first molecule with the second molecule, and (b) increasing the temperature of the target matrix to disassemble the particles at the target matrix.
FILED	Friday, July 29, 2016
APPL NO	15/747552
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/39 (20130101) A61K 41/0028 (20130101) Original (OR) Class A61K 47/62 (20170801) A61K 47/6907 (20170801) A61K 47/6931 (20170801) A61K 47/6935 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 35/00 (20180101) Peptides C07K 14/78 (20130101)
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10639593 — Methods to enhance separation performance of metal-organic framework membranes

US 10639593	Jeong et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Hae-Kwon Jeong (College Station, Texas); Hyuk Taek Kwon (College Station, Texas)
ABSTRACT	A method produces a metal-organic framework on a surface of another metal-organic framework. One embodiment comprises contacting the first metal-organic framework with a ligand and solvent solution; wherein the first metal-organic framework comprises a first ligand and a first metal; wherein the ligand and solvent solution comprises a second ligand that is different from the first ligand in the first metal-organic framework; and allowing the second ligand from the ligand and solvent solution to exchange with the first ligand present in the first metal-organic framework for a period of time suitable to produce the second metal-organic framework on the surface of the first metal-organic framework.
FILED	Thursday, September 14, 2017
APPL NO	15/704785
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) Original (OR) Class B01D 2325/02 (20130101)
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10639620 — Catalyst for ring expansion metathesis polymerization of cyclic monomers

US 10639620	Veige et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Adam S. Veige (Gainesville, Florida); Stella Almeida Gonsales (Gainesville, Florida)
ABSTRACT	A tetraanionic OCO pincer ligand metal-oxo-alkylidene complex is prepared from a trianionic pincer ligand supported metal-alkylidyne. The metal can be tungsten or other group 5-7 transition metal. The tetraanionic pincer ligand metal-oxo-alkylidene complex, a trianionic OCO pincer ligand metal complex, or a trianionic ONO pincer ligand metal complex can be used to polymerize cycloalkenes. The poly(cycloalkene)s are predominantly cis-alkene macrocyclics.
FILED	Monday, September 19, 2016
APPL NO	15/760730
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/223 (20130101) Original (OR) Class B01J 31/2243 (20130101) B01J 31/2265 (20130101) B01J 31/2286 (20130101) B01J 2231/14 (20130101) B01J 2231/543 (20130101) B01J 2531/66 (20130101) B01J 2531/0244 (20130101) B01J 2540/10 (20130101) B01J 2540/225 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/69 (20130101) C08F 32/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 2261/13 (20130101) C08G 2261/418 (20130101) C08G 2261/3324 (20130101)
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10640649 — Solvent-free supersoft and superelastic materials

US 10640649	Sheiko et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Sergei Sheiko (Chapel Hill, North Carolina); Mohammad Vatankhah Varnoosfaderani (Carrboro, North Carolina); Will Daniel (Carrboro, North Carolina)
ABSTRACT	The invention generally relates to compositions comprising polymer bottle brush and comb networks and methods of making polymer networks. Specifically, the disclosed polymer networks are prepared by polymerizing a siloxane monomer in the presence of a crosslinker. Alternatively, the disclosed polymer networks can be prepared by polymerizing a siloxane monomer in the presence of a radical initiator. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Friday, July 22, 2016
APPL NO	15/742741
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) C08F 220/16 (20130101) C08F 220/16 (20130101) C08F 230/08 (20130101) C08F 230/08 (20130101) C08F 236/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/442 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 83/00 (20130101) C08L 83/06 (20130101) Original (OR) Class C08L 83/06 (20130101)
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10640707 — Compositions comprising anisotropic nanoparticle liquid crystal dispersions having tunable optical properties

US 10640707	Liu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Quingkun Liu (Boulder, Colorado); Ivan Smalyukh (Boulder, Colorado)
ABSTRACT	Disclosed herein are compositions, comprising one or more types of surface modified anisotropic nanoparticles dispersed in a liquid crystal. The compositions provide tunable methods for modifying light and energy flow.
FILED	Tuesday, September 22, 2015
APPL NO	15/512793
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/22 (20130101) Original (OR) Class C09K 2019/122 (20130101) C09K 2019/521 (20130101) C09K 2019/3009 (20130101)
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10640781 — Modification of transcriptional repressor binding site in NF-YC4 promoter for increased protein content and resistance to stress

US 10640781	Li et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Ling Li (Mississippi State, Iowa); Eve Syrkin Wurtele (Ames, Iowa)
ABSTRACT	Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; hybrid plants; and seeds.
FILED	Wednesday, February 17, 2016
APPL NO	15/550781
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) A01H 5/00 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8205 (20130101) C12N 15/8216 (20130101) C12N 15/8241 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) Original (OR) Class C12N 15/8279 (20130101)
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10640813 — Exchange-induced remnant magnetization for label-free detection of DNA, micro-RNA, and DNA/RNA-binding biomarkers

US 10640813	Xu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	University of Houston System (Houston, Texas)
INVENTOR(S)	Shoujun Xu (Houston, Texas); Li Yao (Houston, Texas); Yuhong Wang (Houston, Texas); Qiongzheng Hu (Houston, Texas); Haopeng Yang (Houston, Texas)
ABSTRACT	A method of using an exchange-induced remnant magnetization (EXIRM) technique for label free detection of short strands of nucleotides and cancer biomarkers, such as DNA and microRNA strands, DNA/RNA-binding biomarkers, and cancer-specific antigens, with high sensitivity, high specificity, and broad dynamic range. The method may provide a label-free approach aimed to facilitate high reliability, and to require a minimum amount of biochemical reagents.
FILED	Thursday, October 25, 2018
APPL NO	16/170208
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class
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10640915 — Moisture control fabrics

US 10640915	Xing et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	DRYCO, INC. (Brooklyn, New York)
ASSIGNEE(S)	DRYCO, INC. (Brooklyn, New York)
INVENTOR(S)	Siyuan Xing (Newark, California); Rachel Foote (San Leandro, California)
ABSTRACT	The present disclosure provides articles of manufacture with improved moisture control as well as methods of making such articles. In some embodiments, provided herein the article has a fabric with an outer hydrophobic surface and an inner surface with hydrophobic and hydrophilic regions where the hydrophilic regions can form a pattern, allowing moisture to collect and move through the pattern, and the hydrophobic regions prevent the whole inner surface from becoming moist and the outer hydrophobic regions does not show moisture. The fabric may be used to make garments. The entire inner surface of the garment may be patterned with hydrophilic patterns for partial absorption, and the entire outer surface of the garment is hydrophobic, thereby preventing perspiration from being seen from outside of the garment. Further provided herein are methods of making fabrics with improved moisture control including by printing or knitting.
FILED	Tuesday, April 09, 2019
APPL NO	16/378752
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Shirts; Underwear; Baby Linen; Handkerchiefs A41B 9/06 (20130101) A41B 11/00 (20130101) A41B 17/00 (20130101) A41B 2400/62 (20130101) A41B 2500/20 (20130101) Corsets; Brassieres A41C 3/00 (20130101) Outerwear; Protective Garments; Accessories A41D 1/06 (20130101) A41D 1/14 (20130101) A41D 1/22 (20130101) A41D 3/02 (20130101) A41D 31/02 (20130101) A41D 2500/20 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/04 (20130101) B32B 5/08 (20130101) B32B 5/26 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 25/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 15/21 (20130101) Original (OR) Class D06M 2200/12 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/021 (20130101) D10B 2501/00 (20130101)
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10641651 — Ultrasonic microphone and ultrasonic acoustic radio

US 10641651	Zhou et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises 5 a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range
FILED	Wednesday, February 24, 2016
APPL NO	15/558467
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101)
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10641694 — Measuring interfacial tension using electrostatic oscillations

US 10641694	Narayanan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); NATIONAL SCIENCE FOUNDATION (Alexandria, Virginia)
INVENTOR(S)	Ranganathan Narayanan (Gainesville, Florida); Kevin L. Ward (Gainesville, Florida)
ABSTRACT	An exemplary embodiment of an interfacial tension measurement system of the present disclosure is one in which Faraday waves or instability are formed within a vessel of fluids to be tested via electrostatic oscillations. Then, by tracking the amplitude of an applied electrical voltage having an AC harmonic load to the mixture of fluids that result in a Faraday instability, as well as the wavelength of the instability, the interfacial tension measurement system determines the interfacial tension between layers of immiscible liquids present in the vessel.
FILED	Friday, April 13, 2018
APPL NO	15/953026
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/02 (20130101) Original (OR) Class
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10642014 — Biodynamic microscopes and methods of use thereof

US 10642014	Nolte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	David D. Nolte (Lafayette, Indiana); John J. Turek (West Lafayette, Indiana); Ran An (West Lafayette, Indiana)
ABSTRACT	An apparatus for viewing a biological sample that functions as both a microscope and an interferometer. A short-coherence light source directs light onto the sample. A Fourier transform lens and a pixel-array detector are positioned to collect light scattered by the sample. An optic fiber assembly conveys a reference beam from the short-coherence light source. The detector collects the reference beam and the signal beam and uses coherence gating to acquire interferometric image data. In some embodiments the axis of the incident light striking the sample and the axis of collected scattered signal light form an angle of less than 180 degrees and advantageously an angle between 120 and 150 degrees. A method of converting a microscope into an interferometer is also disclosed.
FILED	Friday, March 11, 2016
APPL NO	15/068275
ART UNIT	2488 — Recording and Compression
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/2804 (20130101) G02B 21/14 (20130101) G02B 21/24 (20130101) G02B 21/086 (20130101) G02B 21/0088 (20130101) Original (OR) Class G02B 21/365 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/212 (20130101) Holographic Processes or Apparatus G03H 1/0443 (20130101) G03H 1/0465 (20130101) G03H 2001/005 (20130101) G03H 2001/0445 (20130101) G03H 2001/0467 (20130101) G03H 2222/24 (20130101)
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10642407 — Method and apparatus for classifying touch events on a touch sensitive surface

US 10642407	Harrison et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Christopher Harrison (Pittsburgh, Pennsylvania); Julia Schwarz (Pittsburgh, Pennsylvania); Scott E. Hudson (Pittsburgh, Pennsylvania)
ABSTRACT	An apparatus classifies touch events. The apparatus includes a touch sensitive surface configured to generate a touch event when an object touches the touch sensitive surface. The touch event entails a mechanical vibration upon contact with the surface. The apparatus includes a touch event detector configured to detect the onset of a touch, and a touch event classifier configured to classify the touch event to identify the object used for the touch event. The mechanical vibration is created via any one of finger parts including a tip, a pad, a fingernail, and a knuckle, each of which has a unique feature different from each other.
FILED	Friday, December 08, 2017
APPL NO	15/836798
ART UNIT	2628 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/043 (20130101) G06F 3/044 (20130101) G06F 3/0416 (20130101) Original (OR) Class G06F 3/0433 (20130101) G06F 2200/1636 (20130101) G06F 2203/04106 (20130101)
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10642419 — Probabilistic palm rejection using spatiotemporal touch features and iterative classification

US 10642419	Schwarz et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Julia Schwarz (Pittsburgh, Pennsylvania); Chris Harrison (Pittsburgh, Pennsylvania)
ABSTRACT	The disclosed subject matter is a palm rejection technique utilizing temporal features, iterative classification, and probabilistic voting. Touch events are classified based on features periodically extracted from time windows of increasing size, always centered at the birth of the event. The classification process uses a series of decision trees acting on said features.
FILED	Monday, July 23, 2018
APPL NO	16/042836
ART UNIT	2622 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/0418 (20130101) Original (OR) Class
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10642945 — Structural weak spot analysis

US 10642945	Zhou et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Qingnan Zhou (New York, New York); Denis Zorin (New York, New York); Julian Panetta (New York, New York)
ABSTRACT	A system and methods for weak spot analysis. A mesh shape is preprocessed to approximate an input model for an object. The mesh shape is analyzed with modal analysis to identify weak regions. A method and system for determining weak spots in an object. The method and system uses an optimization problem which is solved to determine a pressure distribution on the object maximizing maximal principal stress by solving a set of optimization problems maximizing stress for each point of the object.
FILED	Wednesday, October 23, 2013
APPL NO	14/438181
ART UNIT	2127 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class
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10642975 — System and methods for automatically detecting deceptive content

US 10642975	Ott et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS) Directorate for Social, Behavioral and Economic Sciences (SBE) Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Myle Ott (Ithaca, New York); Yejin Choi (Westbury, New York); Claire Cardie (Ithaca, New York); Jeffrey Hancock (Ithaca, New York)
ABSTRACT	Systems and methods for detecting deceptive opinion spam. Certain embodiments include a classifier with improved accuracy for detecting deceptive opinion entries. A feature analysis of learned models reveals a relationship between deceptive opinions and imaginative writing. By modeling deception in a generative framework, the prevalence of deception in two popular online review communities may be determined. Deceptive opinion spam is a rapidly growing and widespread problem, especially in review communities with minimal posting requirements.
FILED	Thursday, October 18, 2012
APPL NO	14/352350
ART UNIT	2123 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/274 (20130101) G06F 21/552 (20130101) Original (OR) Class G06F 2221/034 (20130101)
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10643397 — Window-shaping virtual reality system

US 10643397	Huo et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Ke Huo (West Lafayette, Indiana); Vinayak Raman Krishnamurthy (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana)
ABSTRACT	A virtual reality system, comprising an electronic 2d interface having a depth sensor, the depth sensor allowing a user to provide input to the system to instruct the system to create a virtual 3D object in a real-world environment. The virtual 3D object is created with reference to at least one external physical object in the real-world environment, with the external physical object concurrently displayed with the virtual 3D object by the interface. The virtual 3D object is based on physical artifacts of the external physical object.
FILED	Monday, March 19, 2018
APPL NO	15/925758
ART UNIT	2623 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/041 (20130101) G06F 3/0482 (20130101) G06F 3/03545 (20130101) G06F 3/04815 (20130101) G06F 3/04883 (20130101) G06F 2203/04104 (20130101) G06F 2203/04808 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) G06T 7/40 (20130101) G06T 15/04 (20130101) G06T 17/20 (20130101) G06T 19/006 (20130101) G06T 19/20 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2219/2004 (20130101) G06T 2219/2016 (20130101) G06T 2219/2021 (20130101)
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10643487 — Communication and skills training using interactive virtual humans

US 10643487	Lok et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida); Augusta University Research Institute, Inc. (Augusta, Georgia)
ASSIGNEE(S)	August University Research Institute, Inc. (Augusta, Georgia); University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Benjamin Chak Lum Lok (Gainesville, Florida); David Scott Lind (Martinez, Georgia); Juan Carlos Cendan (Gainesville, Florida); Andrew Brian Raij (Winter Park, Florida); Brent H. Rossen (Gainesville, Florida); Aaron Andrew Kotranza (Gainesville, Florida); Kyle John Johnsen (Athens, Georgia)
ABSTRACT	A system for providing interaction between a virtual human and a user, the system comprising: a tangible interface providing a physical interface between the user and the virtual human, an imaging system directed towards the physical interface to provide images of the user interacting with the tangible interface; a tracking system tracking at least one position or the user; a microphone capturing speech from the user; a simulation system receiving inputs from the tangible interface, the imaging system, the tracking system and the microphone, the simulation system generating output signals corresponding to the virtual human; and a display presenting the output signals to the user.
FILED	Monday, April 30, 2018
APPL NO	15/967205
ART UNIT	2625 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 19/00 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/00 (20130101) Original (OR) Class G09B 23/28 (20130101)
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10643694 — Partial-polarization resistive electronic devices, neural network systems including partial-polarization resistive electronic devices and methods of operating the same

US 10643694	Alessandri et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S)	Cristobal Alessandri (Notre Dame, Indiana); Erich Kinder (Notre Dame, Indiana); Alan C. Seabaugh (Notre Dame, Indiana)
ABSTRACT	An electronic device can include a semiconductor material including a channel region configured to conduct a current, a source contact electrically coupled to the channel region at a first location, a drain contact electrically coupled to the channel region at a second location spaced apart from the first location, a partial-polarization material on the semiconductor material between the source contact and the drain contact opposite the channel region and a gate contact on the partial-polarization material opposite the channel region and ohmically coupled to the drain contact or ohmically coupled to the source contact.
FILED	Monday, November 05, 2018
APPL NO	16/180453
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/0635 (20130101) Static Stores G11C 13/0004 (20130101) G11C 13/004 (20130101) Original (OR) Class G11C 2213/73 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/147 (20130101)
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10644144 — Growth of cubic crystalline phase structure on silicon substrates and devices comprising the cubic crystalline phase structure

US 10644144	Brueck et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Steven R. J. Brueck (Albuquerque, New Mexico); Seung-Chang Lee (Albuquerque, New Mexico); Christian Wetzel (Troy, New York); Mark Durniak (Troy, New York)
ABSTRACT	A transistor comprises a substrate comprising a Group III/V compound semiconductor material having a cubic crystalline phase structure positioned on a hexagonal crystalline phase layer having a first region and a second region, the cubic crystalline phase structure being positioned between the first region and the second region of the hexagonal crystalline phase layer. A source region and a drain region are both positioned in the Group III/V compound semiconductor material. A channel region is in the Group III/V compound semiconductor material. A gate is over the channel region. An optional backside contact can also be formed. A source contact and electrode are positioned to provide electrical contact to the source region. A drain contact and electrode are positioned to provide electrical contact to the drain region. Methods of forming transistors are also disclosed.
FILED	Wednesday, November 14, 2018
APPL NO	16/191197
ART UNIT	2813 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0243 (20130101) H01L 21/0251 (20130101) H01L 21/0254 (20130101) H01L 21/02381 (20130101) H01L 21/02395 (20130101) H01L 21/02433 (20130101) H01L 21/02458 (20130101) H01L 21/02494 (20130101) H01L 21/02502 (20130101) H01L 21/02587 (20130101) H01L 21/02609 (20130101) H01L 21/7806 (20130101) H01L 21/30604 (20130101) H01L 29/04 (20130101) H01L 29/045 (20130101) H01L 29/78 (20130101) H01L 29/205 (20130101) H01L 29/402 (20130101) H01L 29/0657 (20130101) H01L 29/0847 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/42316 (20130101) H01L 29/66462 (20130101) H01L 33/007 (20130101) H01L 33/24 (20130101) H01L 33/32 (20130101) H01L 33/0079 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/22 (20130101) H01S 5/227 (20130101) H01S 5/3203 (20130101) H01S 5/34333 (20130101)
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10644735 — Circuits and methods for detecting interferers

US 10644735	Kinget et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Peter R. Kinget (Summit, New Jersey); John Wright (New York, New York); Rabia Tugce Yazicigil (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Peter R. Kinget (Summit, New Jersey); John Wright (New York, New York); Rabia Tugce Yazicigil (New York, New York)
ABSTRACT	Mechanisms for interferer detection can detect interferers by detecting elevated signal amplitudes in one or more of a plurality of bins (or bands) in a frequency range between a maximum frequency (f_MAX) and a minimum frequency (f_MIN). To perform rapid interferer detection, the mechanisms downconvert an input signal x(t) with a local oscillator (LO) to a complex baseband signal x_I(t)+jx_Q(t). x_I(t) and x_Q(t) are then multiplied by m unique pseudorandom noise (PN) sequences (e.g., Gold sequences) g_m(t) to produce m branch signals for I and m branch signals for Q. The branch signals are then low pass filtered, converted from analog to digital form, and pairwise combined by a pairwise complex combiner. Finally, a support recovery function is used to identify interferers.
FILED	Monday, August 14, 2017
APPL NO	15/676610
ART UNIT	2633 — Digital Communications
CURRENT CPC	Transmission H04B 1/1027 (20130101) Original (OR) Class H04B 17/345 (20150115) Multiplex Communication H04J 13/0029 (20130101)
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10644771 — Using artificial signals to maximize capacity and secrecy of multiple-input multiple-output (MIMO) communication

US 10644771	Pekoz et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Berker Pekoz (Tampa, Florida); Mohammed Hafez (Lutz, Florida); Selcuk Kose (Pittsford, New York); Huseyin Arslan (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Berker Pekoz (Tampa, Florida); Mohammed Hafez (Lutz, Florida); Selcuk Kose (Pittsford, New York); Huseyin Arslan (Tampa, Florida)
ABSTRACT	A system and method for increasing the capacity of a Multiple-Input Multiple-Output (MIMO) system at desired user's locations and reducing the capacity at locations, other than that of the desired user, while also providing secrecy. Knowing the channel coefficient between each transmitter and receiver antenna pair at the transmitter, the method of the present invention calculates the artificial signal that minimizes the Euclidean distance between the desired and received data symbols if the precoding/combining matrix pair from the set that has the minimum Euclidean distance to the singular value decomposition (SVD) of the channel matrix is used for transmission and reception. The artificial signal may be fed to the precoder, instead of the actual desired data symbols, or may be transmitted directly to reduce computational complexity, power consumption and processing delay if the hardware configuration allows.
FILED	Tuesday, December 03, 2019
APPL NO	16/702068
ART UNIT	2637 — Optical Communications
CURRENT CPC	Transmission H04B 7/046 (20130101) Original (OR) Class H04B 7/0417 (20130101) H04B 7/0626 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0042 (20130101) H04L 25/0204 (20130101)
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10644801 — Proactive channel probing for wavelength switching in optical transmission systems

US 10644801	Kilper et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Daniel Kilper (Tucson, Arizona); Weiyang Mo (Tucson, Arizona); Houman Rastegarfar (Tucson, Arizona); Mariya A. Bhopalwala (Tucson, Arizona)
ABSTRACT	A proactive and non-obtrusive channel probing scheme is provided to accurately predict channel power, gain, and optical signal to noise ratio (OSNR) without disrupting the existing connections. In one example, using a probe signal with 5 μs pulse duration in a single-hop network, rapid wavelength switching is achieved with power excursions less than or equal to 0.2 dB for different loading configurations.
FILED	Thursday, June 29, 2017
APPL NO	16/311215
ART UNIT	2637 — Optical Communications
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1301 (20130101) Transmission H04B 10/296 (20130101) H04B 10/0775 (20130101) H04B 10/2935 (20130101) H04B 10/2942 (20130101) Original (OR) Class H04B 2210/078 (20130101) Multiplex Communication H04J 14/02 (20130101) H04J 14/0241 (20130101) H04J 14/0278 (20130101)
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10645812 — System and methods for additive manufacturing of electromechanical assemblies

US 10645812	MacCurdy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Robert MacCurdy (Ithaca, New York); Hod Lipson (New York, New York)
ABSTRACT	A hybrid additive manufacturing approach that incorporates three-dimensional (3D) printing and placement of modules selected from a library of modules to fabricate an electromechanical assembly. By virtue of fabrication of the electromechanical assembly, mechanical properties and electrical properties of the assembly are created. The invention overcomes the material and process limitations of current printable electronics approaches, enabling complete, complex electromechanical assemblies to be fabricated.
FILED	Tuesday, April 21, 2015
APPL NO	15/305962
ART UNIT	1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/00 (20170801) B29C 65/16 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 80/00 (20141201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/56 (20130101) H01L 21/67115 (20130101) H01L 21/67132 (20130101) H01L 23/5384 (20130101) H01L 23/5389 (20130101) H01L 25/18 (20130101) H01L 25/50 (20130101) H01L 25/112 (20130101) H01L 27/01 (20130101) H01L 27/13 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/14 (20130101) H05K 1/16 (20130101) H05K 1/113 (20130101) H05K 1/115 (20130101) H05K 1/117 (20130101) H05K 1/185 (20130101) Original (OR) Class H05K 1/0287 (20130101) H05K 3/0014 (20130101) H05K 3/30 (20130101) H05K 3/125 (20130101) H05K 3/284 (20130101) H05K 3/368 (20130101) H05K 3/4673 (20130101) H05K 3/4697 (20130101) H05K 2201/1003 (20130101) H05K 2201/10015 (20130101) H05K 2201/10022 (20130101) H05K 2201/10053 (20130101) H05K 2201/10106 (20130101) H05K 2201/10166 (20130101) H05K 2201/10174 (20130101) H05K 2201/10189 (20130101) H05K 2201/10636 (20130101) H05K 2203/107 (20130101) H05K 2203/1327 (20130101)
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National Aeronautics and Space Administration (NASA)

10639802 — Systems and methods for post-treatment of dry adhesive microstructures

US 10639802	Dadkhah Tehrani et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	ONROBOT LOS ANGELES INC. (Los Angeles, California)
ASSIGNEE(S)	ONROBOT LOS ANGELES INC. (Los Angeles, California)
INVENTOR(S)	Mohammad Dadkhah Tehrani (Los Angeles, California); Nicholas Wettels (Los Angeles, California)
ABSTRACT	Provided are systems and methods for the post-treatment of dry adhesive microstructures. The microstructures may be post-treated to comprise mushroom-like flaps at their tips to interface with the contact surface. In some aspects, a change in material composition of the microstructures in a dry adhesive may affect mechanical properties to enhance or diminish overall adhesive performance. For example, conductive additives can be added to the material to improve adhesive performance. In other aspects, microstructures comprising conductive material may allow for pre-load engagement sensing systems to be integrated into the microstructures.
FILED	Tuesday, May 07, 2019
APPL NO	16/405398
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 15/0085 (20130101) Original (OR) Class Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2207/056 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00 (20130101) B81C 1/00206 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/041 (20170501) C08K 2201/001 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) C09J 9/02 (20130101) C09J 11/04 (20130101) C09J 201/00 (20130101) C09J 2201/626 (20130101)
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10640720 — Process for generating cool flame and flameless fuel oxidation using non-equilibrium plasma activation

US 10640720	Ju et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Yiguang Ju (Princeton, New Jersey); Sang Hee Won (Monmouth Juncton, New Jersey); Weiqi Sun (Princeton, New Jersey)
ABSTRACT	An exemplary embodiment can be an exemplary method, which can include, for example, generating a cool flame(s) using a plasma-assisted combustion, and maintaining the cool flame(s). The cool flame(s) can have a temperature below about 1050 Kelvin, which can be about 700 Kelvin. The cool flame(s) can be further generated using a heated counterflow burning arrangement and a an ozone generating arrangement. The heated counterflow burning arrangement can include a liquid fuel vaporization arrangement. The ozone generating arrangement can include a micro plasma dielectric barrier discharge arrangement. The plasma-assisted combustion can be generated using (i) liquid n-heptane, (i) heated nitrogen, and (iii) ozone.
FILED	Friday, April 03, 2015
APPL NO	15/301590
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 10/00 (20130101) Original (OR) Class Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 99/001 (20130101) F23C 2900/99001 (20130101) F23C 2900/99005 (20130101) Removal or Treatment of Combustion Products or Combustion Residues; Flues F23J 7/00 (20130101) Feeding Fuel to Combustion Apparatus F23K 2401/10 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/342 (20130101) Y02E 20/344 (20130101)
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10640873 — Optical printing systems and methods

US 10640873	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Aeronautics and Space Administration (NASA)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Yuebing Zheng (Austin, Texas); Bharath Bangalore Rajeeva (Austin, Texas)
ABSTRACT	Disclosed herein are methods comprising: illuminating a first location of an optothermal substrate with electromagnetic radiation; wherein the optothermal substrate converts at least a portion of the electromagnetic radiation into thermal energy; and wherein the optothermal substrate is in thermal contact with a liquid sample comprising a plurality of thermally reducible metal ions; thereby: generating a confinement region at a location in the liquid sample proximate to the first location of the optothermal substrate; trapping at least a portion of the plurality of thermally reducible metal ions within the confinement region; and thermally reducing the trapped portion of the plurality of thermally reducible metal ions; thereby: depositing a metal particle on the optothermal substrate at the first location. Also disclosed herein are systems for performing the methods described herein. Also disclosed herein are patterned substrates made by the methods described herein, and methods of use thereof.
FILED	Thursday, December 20, 2018
APPL NO	16/227292
ART UNIT	2886 — Optics
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/182 (20130101) C23C 18/1612 (20130101) Original (OR) Class C23C 18/1667 (20130101) C23C 18/1817 (20130101) C23C 18/1865 (20130101) C23C 18/1868 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 2021/651 (20130101)
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10641615 — Methods and apparatus for displaying flight interval management data for selecting appropriate flight management settings

US 10641615	Mohan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S)	Rajeev Mohan (Bangalore, India); Ravish Udupa (Bangalore, India); Ruben Carrillo (Phoenix, Arizona); Shashi Kumar Namde (Bangalore, India)
ABSTRACT	A method and system for aircraft management for selecting a speeding profile mode for phases of a flight plan including: retrieving assigned space goals (ASG) corresponding to a plurality of achieve by point (ABP) designations for a target flight path of the aircraft wherein the target flight path is associated with a target aircraft; determining a target air speed and applicable speed profile modes by retrieving prior information of traffic history and flight plans of the target aircraft to achieve the ABP designations corresponding to an ASG retrieved; selecting from a plurality of applicable speed profile modes, at least one applicable speed profile mode for a phase of the target flight plan for the aircraft; and comparing statuses of the aircraft of at least a status of fuel remaining for a combination of the selection of the applicable speed profile mode and the phase of the target flight plan.
FILED	Friday, August 11, 2017
APPL NO	15/675256
ART UNIT	3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/00 (20130101) Original (OR) Class Traffic Control Systems G08G 5/003 (20130101) G08G 5/0013 (20130101) G08G 5/0021 (20130101) G08G 5/025 (20130101) G08G 5/0047 (20130101) G08G 5/0052 (20130101) G08G 5/0078 (20130101)
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10641616 — Remote sensing calibration, validation, and signature characterization from unmanned aircraft systems

US 10641616	Padula et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	GeoThinkTank LLC (Alelxandria, Virginia)
ASSIGNEE(S)
INVENTOR(S)	Francis Padula (Alexandria, Virginia); Aaron Pearlman (Alexandria, Virginia)
ABSTRACT	A method, computer program product and system where a processor(s) configures sensor(s) on an unmanned aircraft system, to capture data related to a surface of a defined geographic area. The processor(s) navigate the unmanned aircraft system in a repeatable defined travel path proximate to the defined geographic area, such that the sensor(s) capture surface data related to the defined geographic area during the navigating, wherein a position of the unmanned aircraft system in the travel path is within a satellite view geometry of a satellite. The processor(s) maintain the unmanned aircraft system at a distance from the surface at which atmosphere does not obscure the data and obtain the data collected by the sensor(s). The processor(s) compares the data collected by the sensor(s) to data collected by one or more instruments on the satellite related to the defined geographic area to determine is the instrument(s) of the satellite are calibrated.
FILED	Thursday, February 02, 2017
APPL NO	15/423372
ART UNIT	2865 — Printing/Measuring and Testing
CURRENT CPC	Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/123 (20130101) B64C 2201/127 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/1014 (20130101) B64G 1/1021 (20130101) B64G 3/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3661 (20130101) G01C 25/00 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/00 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101)
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10641694 — Measuring interfacial tension using electrostatic oscillations

US 10641694	Narayanan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); NATIONAL SCIENCE FOUNDATION (Alexandria, Virginia)
INVENTOR(S)	Ranganathan Narayanan (Gainesville, Florida); Kevin L. Ward (Gainesville, Florida)
ABSTRACT	An exemplary embodiment of an interfacial tension measurement system of the present disclosure is one in which Faraday waves or instability are formed within a vessel of fluids to be tested via electrostatic oscillations. Then, by tracking the amplitude of an applied electrical voltage having an AC harmonic load to the mixture of fluids that result in a Faraday instability, as well as the wavelength of the instability, the interfacial tension measurement system determines the interfacial tension between layers of immiscible liquids present in the vessel.
FILED	Friday, April 13, 2018
APPL NO	15/953026
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/02 (20130101) Original (OR) Class
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10643754 — Passive reactivity control of nuclear thermal propulsion reactors

US 10643754	Venneri et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Ultra Safe Nuclear Corporation (Los Alamos, New Mexico)
ASSIGNEE(S)	Ultra Safe Nuclear Corporation (Seattle, Washington)
INVENTOR(S)	Paolo Francesco Venneri (Los Alamos, New Mexico); Michael John Eades (Los Alamos, New Mexico)
ABSTRACT	Passive reactivity control technologies that enable reactivity control of a nuclear thermal propulsion (NTP) system with little to no active mechanical movement of circumferential control drums. By minimizing or eliminating the need for mechanical movement of the circumferential control drums during an NTP burn, the reactivity control technologies simplify controlling an NTP reactor and increase the overall performance of the NTP system. The reactivity control technologies mitigate and counteract the effects of xenon, the dominant fission product contributing to reactivity transients. Examples of reactivity control technologies include, employing burnable neutron poisons, tuning hydrogen pressure, adjusting wait time between burn cycles or merging burn cycles, and enhancement of temperature feedback mechanisms. The reactivity control technologies are applicable to low-enriched uranium NTP systems, including graphite composite fueled and tungsten ceramic and metal matrix (CERMET), or any moderated NTP system, such as highly-enriched uranium graphite composite NTP systems.
FILED	Monday, March 13, 2017
APPL NO	15/457030
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/408 (20130101) Jet-propulsion Plants F02K 9/00 (20130101) F02K 9/48 (20130101) Nuclear Reactors G21C 3/64 (20130101) G21C 3/336 (20130101) G21C 7/04 (20130101) Original (OR) Class G21C 13/032 (20130101) Nuclear Power Plant G21D 5/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) Y02E 30/39 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10645803 — Soft, multilayered electronics for wearable devices and methods to produce the same

US 10645803	Majidi et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S)	Carmel Majidi (Pittsburgh, Pennsylvania); Michael D. Bartlett (Pittsburgh, Pennsylvania); Eric J. Markvicka (Pittsburgh, Pennsylvania)
ABSTRACT	Disclosed herein is an efficient fabrication approach to create highly customizable wearable electronics through rapid laser machining and adhesion-controlled soft materials assembly. Well-aligned, multi-layered materials can be created from 2D and 3D elements that stretch and bend while seamlessly integrating with rigid components such as microchip integrated circuits (IC), discrete electrical components, and interconnects. These techniques are applied using commercially available materials. These materials and methods enable custom wearable electronics while offering versatility in design and functionality for a variety of bio-monitoring applications.
FILED	Wednesday, September 12, 2018
APPL NO	16/129717
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/1123 (20130101) A61B 5/6825 (20130101) A61B 5/6832 (20130101) A61B 2562/12 (20130101) A61B 2562/0261 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/189 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 1/0393 (20130101) H05K 3/0032 (20130101) H05K 3/303 (20130101) H05K 2201/0162 (20130101) H05K 2201/10151 (20130101) H05K 2203/107 (20130101) H05K 2203/166 (20130101)
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Department of Agriculture (USDA)

10638745 — Repellent and attractant composition for dichromatic animals

US 10638745	Werner et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, Represented by the Secretary of Agriculture (Washington, District of Columbia); Arkion Life Sciences, LLC (New Castle, Delaware)
ASSIGNEE(S)	Arkion Life Sciences, LLC (New Castle, Delaware); United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Scott J. Werner (Wellington, Colorado); Kenneth E. Ballinger, Jr. (Kennett Square, Pennsylvania)
ABSTRACT	The combination of a repellent agent or an attractant agent with a wavelength-specific visual cue agent has been found to produce an unexpected and synergistic effect of increased repellency or attraction in dichromatic animals who are not maximally sensitive to the wavelength of the repellent or attractant agent. The method of the invention may be used to repel dichromatic-animal pests; or to prevent or minimize monetary damage, particularly to agricultural products, natural resources or private property. The method of the invention may also be used to attract dichromatic animals for the purpose of agricultural production, recreational opportunities (e.g., wild-rodent feeders), or the effective administration of target-animal pharmaceuticals or mitigation techniques.
FILED	Wednesday, January 04, 2017
APPL NO	15/398060
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 29/08 (20130101) Original (OR) Class Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 33/04 (20130101) A01N 35/04 (20130101) A01N 35/06 (20130101) A01N 35/06 (20130101) A01N 37/04 (20130101) A01N 37/10 (20130101) A01N 43/90 (20130101) A01N 47/22 (20130101) A01N 53/00 (20130101) A01N 57/16 (20130101)
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10638754 — Methods of attracting Drosophila suzukii using acetoin blend

US 10638754	Zhang et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Aijun Zhang (Laurel, Maryland); Yan Feng (Frederick, Maryland)
ABSTRACT	Methods of attracting Drosophila suzukii, involving treating an object or area with a Drosophila suzukii attracting effective amount of a composition containing acetoin and at least one compound selected from ethyl octanoate, acetic acid, ethyl acetate, phenethyl alcohol, or mixtures thereof; wherein said composition does not contain ethanol.
FILED	Thursday, September 06, 2018
APPL NO	16/123496
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 35/02 (20130101) Original (OR) Class A01N 35/02 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 65/34 (20130101) Technologies for Adaptation to Climate Change Y02A 50/326 (20180101)
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10640792 — Fermentation control for optimization of syngas utilization

US 10640792	Atiyeh et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) Department of Transportation (USDOT)
APPLICANT(S)	THE BOARD OF REGENTS FOR OKLAHOMA SATE UNIVERSITY (Stillwater, Oklahoma)
ASSIGNEE(S)	The Board of Regents for Oklahoma State University (Stillwater, Oklahoma)
INVENTOR(S)	Hasan K. Atiyeh (Stillwater, Oklahoma); John Randall Phillips (Middletown, Delaware); Raymond L. Huhnke (Stillwater, Oklahoma)
ABSTRACT	Controlling the gas inlet flow rate and energy input to a fermentation reactor to maximize conversion of syngas by maximizing uptake of hydrogen into a medium relative to carbon dioxide and carbon monoxide based on determined volumetric mass transfer coefficients for hydrogen, carbon monoxide, and carbon dioxide.
FILED	Friday, November 13, 2015
APPL NO	15/526558
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/54 (20130101) C12P 7/065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 3/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101)
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PP031719 — Cotoneaster plant named ‘Emerald Sprite’

US PP31719	Contreras
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	Oregon State University (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Ryan N. Contreras (Corvallis, Oregon)
ABSTRACT	‘Emerald Sprite’ is a new Cotoneaster cultivar with a highly compact, mounding habit, extremely dense foliage, short internodes, and improved fire blight resistance.
FILED	Friday, September 21, 2018
APPL NO	16/350082
ART UNIT	1661 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/00 (20180501) Original (OR) Class
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Department of Commerce (DOC)

10639634 — Vacuum compatible fluid sampler

US 10639634	Liddle et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S)	GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S)	J. Alexander Liddle (Rockville, Maryland); Samuel M. Stavis (North Potomac, Maryland); Glenn E. Holland (Rockville, Maryland)
ABSTRACT	A fluid sampler includes: a sample cell that includes: a substrate comprising: a first port; a second port in fluid communication with the first port; a viewing reservoir in fluid communication with the first port and the second port and that receives the fluid from the first port and communicates the fluid to the second port, the viewing reservoir including: a first view membrane; a second view membrane; and a pillar interposed between the first view membrane and second view membrane, the pillar separating the first view membrane from the second view membrane at a substantially constant separation distance such that a volume of the viewing reservoir is substantially constant and invariable with respect to a temperature and invariable with respect to a pressure to which the sample cell is subjected.
FILED	Thursday, June 01, 2017
APPL NO	15/611557
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502707 (20130101) B01L 9/00 (20130101) B01L 2200/12 (20130101) B01L 2300/06 (20130101) B01L 2300/046 (20130101) B01L 2300/0609 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 23/02 (20130101) G01N 23/04 (20130101) G01N 23/2251 (20130101) G01N 27/4473 (20130101) G01N 27/44791 (20130101) G01N 35/0099 (20130101) G01N 2223/307 (20130101) G01N 2223/418 (20130101) G01N 2223/638 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/16 (20130101) H01J 37/20 (20130101) H01J 2237/2002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/31122 (20130101) H01L 21/47573 (20130101) H01L 2924/1067 (20130101)
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10640850 — Nanoparticle-stabilized immiscible alloys

US 10640850	Li et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Xiaochun Li (Manhattan Beach, California); Lianyi Chen (Madison, Wisconsin); Jiaquan Xu (Madison, Wisconsin)
ABSTRACT	Solid immiscible alloys and methods for making the solid immiscible alloys are provided. The microstructure of the immiscible alloys is characterized by a minority phase comprising a plurality of particles of an inorganic material dispersed in a majority phase comprising a continuous matrix of another inorganic material. The methods utilize nanoparticles to control both the collisional growth and the diffusional growth of the minority phase particles in the matrix during the formation of the alloy microstructure.
FILED	Wednesday, June 27, 2018
APPL NO	16/020175
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/016 (20130101) Alloys C22C 1/02 (20130101) C22C 1/06 (20130101) C22C 1/026 (20130101) C22C 1/1036 (20130101) C22C 21/00 (20130101) C22C 21/003 (20130101) Original (OR) Class C22C 32/0047 (20130101) C22C 2001/1047 (20130101)
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10641655 — Direct absolute spectrometer for direct absolute spectrometry

US 10641655	Ma et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S)	GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S)	Lijun Ma (Rockville, Maryland); Xiao Tang (Gaithersburg, Maryland); Oliver Slattery (Gaithersburg, Maryland)
ABSTRACT	A direct absolute spectrometer includes: a first light source; a second light source; an optical combiner that produces dual light; an optical cell that receives the dual light; an electromagnetically induced transparent medium that is optically transparent to single photon light in a presence of pump light, such that output light is produced; and a filter that filters output light and provides EIT light free from, wherein electromagnetically induced transparent EIT light is a direct and absolute metric of a linewidth and a wavelength of single photon light such that the direct absolute spectrometer provides direct and absolute determination of the linewidth of the single photon light and direct and absolute determination of wavelength at a maximum of intensity of the single photon light.
FILED	Thursday, July 19, 2018
APPL NO	16/039391
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/42 (20130101) G01J 3/0213 (20130101) Original (OR) Class G01J 3/0237 (20130101)
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10641663 — Dynamic force contactor, providing a dynamic force, and calibrating a force sensor to be traceable to the international system of units

US 10641663	Chijioke et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S)	GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S)	Akobuije D Chijioke (Silver Spring, Maryland); Nicholas Vlajic (Frederick, Maryland)
ABSTRACT	A dynamic force contactor includes: a magnet that provides a magnetic field; an electrical conductor that provides an electric field perpendicular to the magnetic field, the electric field from the electrical conductor in combination with the magnetic field from the magnet providing a Lorentzian force; an armature disposed proximate to the magnet, the electrical conductor disposed on the armature such that the armature reciprocates in a reciprocating direction relative to the magnet in response to the Lorentzian force and that produces the dynamic force; and a dynamic force mediator in communication with the electrical conductor and the armature such that: the dynamic force mediator monitors an alternating voltage across the electrical conductor; the dynamic force mediator monitors an alternating current through the electrical conductor; and the dynamic force mediator monitors a reciprocation velocity of the armature.
FILED	Thursday, September 13, 2018
APPL NO	16/130471
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/122 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/064 (20130101) H01F 7/066 (20130101) H01F 7/081 (20130101) H01F 7/121 (20130101) H01F 7/122 (20130101) H01F 7/1844 (20130101)
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Small Business Administration (SBA)

10639802 — Systems and methods for post-treatment of dry adhesive microstructures

US 10639802	Dadkhah Tehrani et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	ONROBOT LOS ANGELES INC. (Los Angeles, California)
ASSIGNEE(S)	ONROBOT LOS ANGELES INC. (Los Angeles, California)
INVENTOR(S)	Mohammad Dadkhah Tehrani (Los Angeles, California); Nicholas Wettels (Los Angeles, California)
ABSTRACT	Provided are systems and methods for the post-treatment of dry adhesive microstructures. The microstructures may be post-treated to comprise mushroom-like flaps at their tips to interface with the contact surface. In some aspects, a change in material composition of the microstructures in a dry adhesive may affect mechanical properties to enhance or diminish overall adhesive performance. For example, conductive additives can be added to the material to improve adhesive performance. In other aspects, microstructures comprising conductive material may allow for pre-load engagement sensing systems to be integrated into the microstructures.
FILED	Tuesday, May 07, 2019
APPL NO	16/405398
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 15/0085 (20130101) Original (OR) Class Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2207/056 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00 (20130101) B81C 1/00206 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/041 (20170501) C08K 2201/001 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) C09J 9/02 (20130101) C09J 11/04 (20130101) C09J 201/00 (20130101) C09J 2201/626 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10640915 — Moisture control fabrics

US 10640915	Xing et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	DRYCO, INC. (Brooklyn, New York)
ASSIGNEE(S)	DRYCO, INC. (Brooklyn, New York)
INVENTOR(S)	Siyuan Xing (Newark, California); Rachel Foote (San Leandro, California)
ABSTRACT	The present disclosure provides articles of manufacture with improved moisture control as well as methods of making such articles. In some embodiments, provided herein the article has a fabric with an outer hydrophobic surface and an inner surface with hydrophobic and hydrophilic regions where the hydrophilic regions can form a pattern, allowing moisture to collect and move through the pattern, and the hydrophobic regions prevent the whole inner surface from becoming moist and the outer hydrophobic regions does not show moisture. The fabric may be used to make garments. The entire inner surface of the garment may be patterned with hydrophilic patterns for partial absorption, and the entire outer surface of the garment is hydrophobic, thereby preventing perspiration from being seen from outside of the garment. Further provided herein are methods of making fabrics with improved moisture control including by printing or knitting.
FILED	Tuesday, April 09, 2019
APPL NO	16/378752
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Shirts; Underwear; Baby Linen; Handkerchiefs A41B 9/06 (20130101) A41B 11/00 (20130101) A41B 17/00 (20130101) A41B 2400/62 (20130101) A41B 2500/20 (20130101) Corsets; Brassieres A41C 3/00 (20130101) Outerwear; Protective Garments; Accessories A41D 1/06 (20130101) A41D 1/14 (20130101) A41D 1/22 (20130101) A41D 3/02 (20130101) A41D 31/02 (20130101) A41D 2500/20 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/04 (20130101) B32B 5/08 (20130101) B32B 5/26 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 25/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 15/21 (20130101) Original (OR) Class D06M 2200/12 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/021 (20130101) D10B 2501/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10643754 — Passive reactivity control of nuclear thermal propulsion reactors

US 10643754	Venneri et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Ultra Safe Nuclear Corporation (Los Alamos, New Mexico)
ASSIGNEE(S)	Ultra Safe Nuclear Corporation (Seattle, Washington)
INVENTOR(S)	Paolo Francesco Venneri (Los Alamos, New Mexico); Michael John Eades (Los Alamos, New Mexico)
ABSTRACT	Passive reactivity control technologies that enable reactivity control of a nuclear thermal propulsion (NTP) system with little to no active mechanical movement of circumferential control drums. By minimizing or eliminating the need for mechanical movement of the circumferential control drums during an NTP burn, the reactivity control technologies simplify controlling an NTP reactor and increase the overall performance of the NTP system. The reactivity control technologies mitigate and counteract the effects of xenon, the dominant fission product contributing to reactivity transients. Examples of reactivity control technologies include, employing burnable neutron poisons, tuning hydrogen pressure, adjusting wait time between burn cycles or merging burn cycles, and enhancement of temperature feedback mechanisms. The reactivity control technologies are applicable to low-enriched uranium NTP systems, including graphite composite fueled and tungsten ceramic and metal matrix (CERMET), or any moderated NTP system, such as highly-enriched uranium graphite composite NTP systems.
FILED	Monday, March 13, 2017
APPL NO	15/457030
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/408 (20130101) Jet-propulsion Plants F02K 9/00 (20130101) F02K 9/48 (20130101) Nuclear Reactors G21C 3/64 (20130101) G21C 3/336 (20130101) G21C 7/04 (20130101) Original (OR) Class G21C 13/032 (20130101) Nuclear Power Plant G21D 5/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) Y02E 30/39 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10645840 — Active electronically steered array with waveguide manifold thermocoupled to ICS as a heatsink

US 10645840	Timmins et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	AvL Technologies, Inc. (Asheville, North Carolina)
ASSIGNEE(S)	AvL Technologies, Inc. (Asheville, North Carolina)
INVENTOR(S)	Ian J. Timmins (Seminole, Florida); Wayne Holt (Dacula, Georgia); Alan Ellis (Candler, North Carolina); Adam C. Gropp (Candler, North Carolina); Keith Edenfield (Weaverville, North Carolina); Bruce Barratt (Asheville, North Carolina)
ABSTRACT	A heatsink for heat dissipation amongst an active electronically steered array (AESA) on a printed circuit board (PCB) includes a metal plate having a first side and a second side; a plurality of integrally formed pockets on the first side of the metal plate each being sized and configured for congruent receipt of a corresponding one of a plurality of functional blocks of the AESA on the PCB; a plurality of waveguide manifolds on the second side of the metal plate including a plurality of holes that launch a wave transmission and a plurality of slots that guide the direction of the wave transmission; and wherein the metal plate prevents localized overheating amongst the AESA by positioning the metal plate on the PCB wherein the plurality of integrally formed pockets and the plurality of holes and the plurality of slots of the plurality of waveguide manifolds facilitate heat dissipation.
FILED	Monday, February 25, 2019
APPL NO	16/284824
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20154 (20130101) H05K 7/20163 (20130101) Original (OR) Class H05K 7/20536 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

10640792 — Fermentation control for optimization of syngas utilization

US 10640792	Atiyeh et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) Department of Transportation (USDOT)
APPLICANT(S)	THE BOARD OF REGENTS FOR OKLAHOMA SATE UNIVERSITY (Stillwater, Oklahoma)
ASSIGNEE(S)	The Board of Regents for Oklahoma State University (Stillwater, Oklahoma)
INVENTOR(S)	Hasan K. Atiyeh (Stillwater, Oklahoma); John Randall Phillips (Middletown, Delaware); Raymond L. Huhnke (Stillwater, Oklahoma)
ABSTRACT	Controlling the gas inlet flow rate and energy input to a fermentation reactor to maximize conversion of syngas by maximizing uptake of hydrogen into a medium relative to carbon dioxide and carbon monoxide based on determined volumetric mass transfer coefficients for hydrogen, carbon monoxide, and carbon dioxide.
FILED	Friday, November 13, 2015
APPL NO	15/526558
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/54 (20130101) C12P 7/065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 3/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

10645068 — Methods and systems for secure digital credentials

US 10645068	Bonnell et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Clayton C Bonnell (Fairfax, Virginia); Kelley A Sullivan (Washington, District of Columbia)
ABSTRACT	Methods and systems for resetting a digital credential within a digital credential based authentication system. The method includes logging a first administrative user into the digital credential system, receiving, from the first administrative user, a first portion of authentication credentials for a first customer, validating, by the first administrative user using the digital credential system, the first portion, logging a second administrative user into the digital credential system, receiving, from the second administrative user, a second portion of authentication credentials for the first customer, receiving the second portion by the second administrative user, validating, by the second administrative user using the digital credential system, the second portion; and resetting the authentication credentials based on the validation of the first portion and second portion.
FILED	Wednesday, December 21, 2016
APPL NO	15/387473
ART UNIT	2492 — Cryptography and Security
CURRENT CPC	Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/06 (20130101) H04L 63/08 (20130101) Original (OR) Class H04L 63/18 (20130101) H04L 63/083 (20130101) H04L 63/102 (20130101) H04L 63/107 (20130101) H04L 63/0853 (20130101) H04L 63/0892 (20130101) H04L 2463/082 (20130101) Wireless Communication Networks H04W 12/00503 (20190101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10644218 — Multichip device with temperature isolating bump bonds

US 10644218	Hathaway et al.
FUNDED BY
APPLICANT(S)	Aaron Ashley Hathaway (Baltimore, Maryland); Robert Miles Young (Ellicott City, Maryland); Patrick Alan Loney (Fairview Park, Ohio); Justin Hackley (Catonsville, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Aaron Ashley Hathaway (Baltimore, Maryland); Robert Miles Young (Ellicott City, Maryland); Patrick Alan Loney (Fairview Park, Ohio); Justin Hackley (Catonsville, Maryland)
ABSTRACT	A superconducting structure is provided that comprises a first superconducting device coupled to a second superconducting device employing a plurality of superconducting bump bond structures. Each of the plurality of superconducting bump bond structures comprise a first normal metal layer disposed on the top surface of a given one of a plurality of first contact pads, a second normal metal layer disposed on the top surface of a given one of a plurality of second contact pads, and a superconducting metal layer disposed between the first normal metal layer and the second normal metal layer. The metal thicknesses of each of the first normal metal layer, the second normal metal layer, and the specific material of the superconducting metal and normal metal are selected to inhibit the transfer of heat between the first superconducting device and the second superconducting device.
FILED	Wednesday, March 13, 2019
APPL NO	16/352512
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/04 (20130101) H01L 39/12 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10644271 — Packaging material for electrochemical cells

US 10644271	Amatucci et al.
FUNDED BY
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Glenn G. Amatucci (Peapack, New Jersey); Anna B. Halajko (Parlin, New Jersey); Linda Wu Sung (Morris Plains, New Jersey); Anthony Ferrer (North Brunswick, New Jersey)
ABSTRACT	The described invention relates to the use of parylene and composites of parylene as a flexible, sealable, and near hermetic barrier packaging material for nonaqueous electrochemical cells. Additionally, the invention relates to the technique of sealing of battery packaging material through the use of ultrasonic energy, and to the use of a low melting temperature inorganic barrier, which is predisposed between higher melting temperature polymer layers, that can be sealed to form a truly hermetic barrier at the interface.
FILED	Monday, June 25, 2018
APPL NO	16/017927
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/0287 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10644314 — Electrode material for lithium batteries

US 10644314	Amatucci et al.
FUNDED BY
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Glenn Amatucci (Peapack, New Jersey); Matthew Y. Lu (North Brunswick, New Jersey); Fadwa Badway (Old Bridge, New Jersey)
ABSTRACT	Substitution of tantalum into the lattice of monoclinic niobium phosphate results in improved reversibility, near 0% irreversible loss, and similar excellent 20 C high rate behavior in large grain material without the formation of electronically conducting nanocomposites. Tantalum substitution into niobium pentaphosphate enables an improved stabilization of the difficult to fabricate monoclinic niobium phosphate phase. Such tantalum-substituted niobium phosphates show excellent potential for use as electrodes in lithium or lithium-ion batteries.
FILED	Tuesday, December 06, 2016
APPL NO	15/776268
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2006/40 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/5825 (20130101) Original (OR) Class H01M 10/052 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 05, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200505.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital