FedInvent™ Patents

Patent Details for Tuesday, May 12, 2020 

This page was updated on Monday, March 27, 2023 at 06:05 AM GMT

Department of Health and Human Services (HHS) 

US 10645912 Nakauchi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE UNIVERSITY OF TOKYO (Bunkyo-ku, Japan);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) THE UNIVERSITY OF TOKYO (Bunkyo-ku, Japan);  THE BOARD OF REGENTS OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Hiromitsu Nakauchi (Tokyo, Japan);  Hideki Masaki (Tokyo, Japan);  Motoo Watanabe (Tokyo, Japan);  Irving Weissman (Stanford, California)
ABSTRACT [Problem to be Solved] The present invention provides a method for producing a chimeric animal using a primed pluripotent stem cell, a tissue stem cell, a progenitor cell, a somatic cell, or a germ cell. [Solution] The method for producing a chimeric animal according to the present invention comprises introducing a mammal-derived cell into the embryo of a mammal, the cell being primed pluripotent stem cell, tissue stem cell, progenitor cell, somatic cell, or germ cell.
FILED Wednesday, January 17, 2018
APPL NO 15/873482
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101) Original (OR) Class
A01K 2207/12 (20130101)
A01K 2227/105 (20130101)

Peptides
C07K 14/4747 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0607 (20130101)
C12N 2501/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646105 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Xingde Li (Ellicott City, Maryland);  Anqi Zhang (Baltimore, Maryland);  Jiefeng Xi (Baltimore, Maryland)
ABSTRACT The present invention is directed to an achromatic endoscope which employs a diffractive microlens. Along with a broadband rotary joint and a custom 800 nm SD-OCT system, ultrahigh-resolution 3D volumetric imaging over a large area becomes possible. The diffractive microlens can be used directly with a GRIN lens, making the endoscope design simpler and cost effective. Preliminary ex vivo 3D intraluminal imaging was performed with the endoscope in conjunction with a home-built broadband rotary joint and a spectral-domain OCT system, demonstrating the performance of the diffractive endoscope. Considering the miniature OCT imaging probe is the required component for using the OCT technology in internal organs, the proposed approach will have a broad impact on endoscopic OCT imaging by improving OCT resolution in any applications that involve a miniature OCT probe, as intravascular OCT imaging, gastrointestinal (GI) tract imaging, airway imaging etc.
FILED Wednesday, September 17, 2014
APPL NO 15/022316
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/002 (20130101)
A61B 1/00096 (20130101)
A61B 1/00172 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646165 Krishnaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
NIH Office of the Director (NIHOD)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Pavitra Krishnaswamy (Boston, Massachusetts);  Patrick L. Purdon (Somerville, Massachusetts);  Emery N. Brown (Brookline, Massachusetts)
ABSTRACT Systems and a method for reducing periodic artifacts in an electrophysiologic signal are provided. The method includes receiving a time-series electrophysiologic signal acquired from a subject and providing a regression model that defines an interference signal caused by periodic artifacts using a harmonic representation. The method also includes applying the regression model using the time-series electrophysiologic signal to define a cost function and performing an iterative optimization process to estimate regression parameters that minimize the cost function. The method further includes determining, using the regression parameters, the interference signal, and generating a corrected time-series electrophysiologic signal by reducing the interference signal.
FILED Thursday, April 10, 2014
APPL NO 14/782479
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/024 (20130101)
A61B 5/055 (20130101)
A61B 5/0476 (20130101)
A61B 5/1102 (20130101)
A61B 5/4064 (20130101)
A61B 5/7203 (20130101) Original (OR) Class
A61B 2576/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646293 Hasser et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Intuitive Surgical Operations, Inc. (Sunnyvale, California)
INVENTOR(S) Christopher J. Hasser (Los Altos, California);  Russell H. Taylor (Severna Park, Maryland);  Joshua Leven (San Francisco, California);  Michael Choti (Lutherville, Maryland)
ABSTRACT A LUS robotic surgical system is trainable by a surgeon to automatically move a LUS probe in a desired fashion upon command so that the surgeon does not have to do so manually during a minimally invasive surgical procedure. A sequence of 2D ultrasound image slices captured by the LUS probe according to stored instructions are processable into a 3D ultrasound computer model of an anatomic structure, which may be displayed as a 3D or 2D overlay to a camera view or in a PIP as selected by the surgeon or programmed to assist the surgeon in inspecting an anatomic structure for abnormalities. Virtual fixtures are definable so as to assist the surgeon in accurately guiding a tool to a target on the displayed ultrasound image.
FILED Monday, January 23, 2017
APPL NO 15/413380
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/3132 (20130101)
A61B 8/00 (20130101)
A61B 8/12 (20130101)
A61B 8/461 (20130101)
A61B 8/4218 (20130101)
A61B 8/4245 (20130101)
A61B 34/25 (20160201)
A61B 34/30 (20160201)
A61B 34/37 (20160201) Original (OR) Class
A61B 34/70 (20160201)
A61B 34/76 (20160201)
A61B 90/03 (20160201)
A61B 90/37 (20160201)
A61B 90/361 (20160201)
A61B 2017/00203 (20130101)
A61B 2034/107 (20160201)
A61B 2034/305 (20160201)
A61B 2090/364 (20160201)
A61B 2090/365 (20160201)
A61B 2090/378 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646295 Stoianovici et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Dan Stoianovici (Reistertown, Maryland);  Doru Petrisor (Lutherville, Maryland);  Dumitru Mazilu (Lutherville, Maryland);  Alexandru Patriciu (Ancaster, Canada);  Lucian Gruionu (Dolj, Romania)
ABSTRACT Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
FILED Friday, February 17, 2017
APPL NO 15/435423
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101)
A61B 34/30 (20160201)
A61B 34/70 (20160201) Original (OR) Class
A61B 90/11 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646356 Deshpande et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Ashish Deshpande (Austin, Texas);  Priyanshu Agarwal (Austin, Texas)
ABSTRACT The present disclosure includes a finger exoskeleton including a plurality of joints and a plurality of sensors configured to measure rotation of at least some of the plurality of joints of the finger exoskeleton. The finger exoskeleton also includes a series elastic actuator comprising a spring element, the series elastic actuator configured to rotate at least one of the plurality of joints. The finger exoskeleton also includes a computing device configured to control operation of the series elastic actuator based on a torque of the at least one of the plurality of joints, the torque determined at least based on the spring element and rotation of the at least one of the plurality of joints. The present disclosure also includes associated methods and hand exoskeletons.
FILED Thursday, June 16, 2016
APPL NO 15/184547
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/586 (20130101) Original (OR) Class
A61F 2002/5007 (20130101)
A61F 2002/5093 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0288 (20130101)
A61H 2201/149 (20130101)
A61H 2201/0165 (20130101)
A61H 2201/165 (20130101)
A61H 2201/501 (20130101)
A61H 2201/1215 (20130101)
A61H 2201/1635 (20130101)
A61H 2201/1676 (20130101)
A61H 2201/5038 (20130101)
A61H 2201/5043 (20130101)
A61H 2201/5046 (20130101)
A61H 2201/5069 (20130101)
A61H 2205/067 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/152 (20130101)
A63B 21/4019 (20151001)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646434 Maisel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Katharina Maisel (Troy, Michigan);  Craig W. Hendrix (Ellicott City, Maryland);  Laura Ensign (Towson, Maryland);  Edward Fuchs (Westminster, Maryland);  Richard Cone (Baltimore, Maryland);  Justin Hanes (Baltimore, Maryland)
ABSTRACT Hypotonic microbicidal compositions including an antimicrobial, such as an antiviral compound, and a pharmaceutically acceptable carrier in a solution formulation having hypotonic osmolarity have been developed for administration rectally to the gastrointestinal mucosa. In a preferred embodiment for use in preventing or decreasing HIV infection, the microbicidal is tenofovir, or a prodrug or derivative thereof. The formulations may include additional agents such as surfactants to enhance cleansing, buffers, or preservatives. Polymers may be included for osmolarity as well as comfort.
FILED Thursday, September 06, 2018
APPL NO 16/123278
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/90 (20130101)
A61K 9/06 (20130101)
A61K 9/0031 (20130101) Original (OR) Class
A61K 9/0034 (20130101)
A61K 9/5146 (20130101)
A61K 9/5153 (20130101)
A61K 31/09 (20130101)
A61K 31/09 (20130101)
A61K 31/52 (20130101)
A61K 31/352 (20130101)
A61K 31/365 (20130101)
A61K 31/365 (20130101)
A61K 31/675 (20130101)
A61K 47/10 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646436 Popov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Alexey Popov (Waltham, Massachusetts);  Elizabeth M. Enlow (Waltham, Massachusetts);  Hongming Chen (Belmont, Massachusetts);  James Bourassa (Somerville, Massachusetts)
ABSTRACT Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
FILED Friday, May 11, 2018
APPL NO 15/977911
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101) Original (OR) Class
A61K 9/5031 (20130101)
A61K 9/5123 (20130101)
A61K 9/5138 (20130101)
A61K 9/5146 (20130101)
A61K 31/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646437 Popov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Alexey Popov (Waltham, Massachusetts);  Elizabeth M. Enlow (Waltham, Massachusetts);  Hongming Chen (Belmont, Massachusetts);  James Bourassa (Somerville, Massachusetts)
ABSTRACT Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
FILED Friday, May 11, 2018
APPL NO 15/977940
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101) Original (OR) Class
A61K 9/5031 (20130101)
A61K 9/5123 (20130101)
A61K 9/5138 (20130101)
A61K 9/5146 (20130101)
A61K 31/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646438 Croyle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Maria A. Croyle (Austin, Texas);  Jin Huk Choi (Austin, Texas);  Stephen Clay Schafer (Austin, Texas)
ABSTRACT Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided.
FILED Wednesday, May 10, 2017
APPL NO 15/591725
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/006 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 47/26 (20130101)
A61K 2039/541 (20130101)
A61K 2039/5256 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/04 (20130101)
C12N 7/00 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10351 (20130101)
C12N 2760/14134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646451 Reinhard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Bjoern Markus Reinhard (Brookline, Massachusetts);  Suryaram Gummuluru (Westwood, Massachusetts)
ABSTRACT Embodiments disclosed herein relates to ganglioside GM3-containing mixed lipids nanoparticles having an overall size between 60-100 nm, the making thereof and the uses. The nanoparticles selectively targeted to CD169+ expressing cells such as dendritic cells and macrophage. The nanoparticles are endocytosed by the CD169+ expressing cells.
FILED Tuesday, May 22, 2018
APPL NO 15/986186
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101)
A61K 9/1272 (20130101)
A61K 9/5115 (20130101)
A61K 9/5123 (20130101) Original (OR) Class
A61K 9/5192 (20130101)
A61K 47/61 (20170801)
A61K 47/543 (20170801)
A61K 47/6911 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646475 Rabinowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Joshua D. Rabinowitz (Princeton, New Jersey);  Hahn Kim (Princeton, New Jersey);  Gregory S. Ducker (Rocky Hill, New Jersey);  Jonathan M. Ghergurovich (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to a method for the treatment of cancer or an autoimmune disorder, comprising the administration of a serine hydroxymethyltransferase (SHMT) inhibitor, and in particular the administration of pyrazolopyran compounds of Formula (VI) as presently described, wherein the compounds are capable of inhibiting a mammalian SHMT, such as human SHMT1 and/or SHMT2. The treatment method further comprises the optional administration of an additional agent as a rescue therapy to reduce toxicity, wherein said agent may be chosen from formate, a formate salt, folinic acid, formate ester, or leucovorin.
FILED Thursday, March 10, 2016
APPL NO 15/552442
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4162 (20130101) Original (OR) Class
A61K 31/4162 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646478 Zon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE (Boston, Massachusetts)
INVENTOR(S) Leonard Zon (Wellesley, Massachusetts);  Richard M. White (Cambridge, Massachusetts)
ABSTRACT Embodiments of the present invention are directed to methods for treatment of melanoma using an inhibitor of dihydroorotate dehydrogenase (DHODH) and to combination therapies that involve administering to a subject an inhibitor of oncogenic BRAF (e.g. BRAF(V600E)), as well as an inhibitor of dihydroorotate dehydrogenase (DHODH). Assays for identifying compounds useful for the treatment of melanoma are also provided. The methods comprise screening for compounds or agents that inhibit neural crest progenitor formation in a zebra fish model of melanoma.
FILED Friday, July 06, 2018
APPL NO 16/029265
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/42 (20130101)
A61K 31/42 (20130101)
A61K 31/44 (20130101) Original (OR) Class
A61K 31/196 (20130101)
A61K 31/381 (20130101)
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646502 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) Lawrence Livermore National Security (Livermore, California)
INVENTOR(S) Sally J. DeNardo (El Macero, California);  Gerald L. DeNardo (El Macero, California);  Rodney L. Balhorn (Livermore, California)
ABSTRACT This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
FILED Wednesday, September 13, 2017
APPL NO 15/703848
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101) Original (OR) Class
A61K 47/55 (20170801)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/545 (20170801)
A61K 47/645 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646505 Schulz et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Michael D. Schulz (South Pasadena, California);  Carl M. Blumenfeld (Weston, Florida);  Robert H. Grubbs (South Pasadena, California);  Julia R. Greer (San Marino, California);  Daryl Wei Liang Yee (Pasadena, California)
ABSTRACT This disclosure is directed to structured compositions, including DNA-functionalized scaffolds, for drug capture, and methods and devices for sequestering chemotherapeutics from physiological fluids using the functionalized scaffolds.
FILED Wednesday, September 06, 2017
APPL NO 15/696474
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101) Original (OR) Class
A61K 47/58 (20170801)
A61K 47/549 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101)
A61L 29/085 (20130101)
A61L 31/08 (20130101)
A61L 31/10 (20130101)
A61L 31/14 (20130101)
A61L 31/16 (20130101)
A61L 2300/258 (20130101)
A61L 2400/12 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/10 (20130101)
C08F 293/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646520 Pamer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Memorial Sloan-Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Eric Pamer (Montclair, New Jersey);  Peter McKenney (New York, New York);  Silvia Caballero (Cambridge, Massachusetts)
ABSTRACT The present invention relates to methods and compositions for reducing the risk and severity of vancomycin-resistant Enterococci infection or colonization. It is based, at least in part, on the discovery that a restricted fraction of the gut microbiota, including the bacteria Clostridium scindens and/or the bacteria Blautia producta contribute substantially to resistance against vancomycin-resistant Enterococci infection or colonization. Without being bound by any particular theory, it is believed that this is achieved through the biosynthesis of secondary bile acids in the case of Clostridium scindens.
FILED Tuesday, May 22, 2018
APPL NO 15/986369
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0031 (20130101)
A61K 9/0043 (20130101)
A61K 9/0053 (20130101)
A61K 35/74 (20130101)
A61K 35/741 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Enzymes
C12Y 101/00 (20130101)
C12Y 101/01201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646540 Glackin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) City of Hope (Duarte, California)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Carlotta A. Glackin (Duarte, California)
ABSTRACT The disclosure provides, inter alia, compositions comprising TWIST peptide inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.
FILED Wednesday, November 15, 2017
APPL NO 15/814204
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/555 (20130101)
A61K 31/555 (20130101)
A61K 31/4745 (20130101)
A61K 31/4745 (20130101)
A61K 33/24 (20130101)
A61K 33/24 (20130101)
A61K 38/10 (20130101) Original (OR) Class
A61K 38/1709 (20130101)
A61K 45/06 (20130101)
A61K 47/64 (20170801)
A61K 47/645 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/4702 (20130101)
C07K 2319/10 (20130101)
C07K 2319/60 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646541 Watnick
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) Randolph S. Watnick (Newton, Massachusetts)
ABSTRACT Provided herein are cyclic prosaposin peptides and compositions and uses thereof. Exemplary uses include use in the treatment of cancer or in the treatment of inflammatory diseases or disorders.
FILED Thursday, March 26, 2015
APPL NO 15/128617
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/12 (20130101) Original (OR) Class

Peptides
C07K 7/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646556 Yost et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Christian Con Yost (North Salt Lake, Utah);  Guy A. Zimmerman (Salt Lake City, Utah);  Andrew S. Weyrich (Salt Lake City, Utah)
ABSTRACT An isolated and purified peptide, neonatal NET-inhibitory Factor (nNIF), is disclosed. Methods for treatment of and prophylaxis against inflammatory disorders are also disclosed, including methods of treatment of and prophylaxis against inflammatory disorders comprising administering NET-inhibitory peptides (NIPs), which may be a nNIF, a pharmaceutically acceptable salt of a nNIF, a nNIF analog, a pharmaceutically acceptable salt of a nNIF analog, a nNIF-Related Peptide (nNRP), including the nNRP, Cancer-Associated SCM-Recognition, Immune Defense Suppression, and Serine Protease Protection Peptide (CRISPP), a pharmaceutically acceptable salt of a nNRP, a nNRP analog, or a pharmaceutically acceptable salt of a nNRP analog, to an individual.
FILED Wednesday, January 23, 2019
APPL NO 16/255545
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/57 (20130101) Original (OR) Class
A61K 38/1709 (20130101)

Peptides
C07K 14/4703 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/385 (20180101)
Y02A 50/387 (20180101)
Y02A 50/473 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646561 Galan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Jorge E. Galan (New Haven, Connecticut);  Jeongmin Song (Hamden, Connecticut)
ABSTRACT The invention provides compositions and methods for using PltA, PltB, CdtB, or a mutant thereof, in inducing or enhancing an immune response.
FILED Thursday, July 21, 2016
APPL NO 15/216373
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 39/0275 (20130101) Original (OR) Class
A61K 2039/575 (20130101)
A61K 2039/55544 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56916 (20130101)
G01N 2333/255 (20130101)
G01N 2800/709 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/59 (20180101)
Y02A 50/484 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646566 Burkhart et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) GLAXOSMITHKLINE BIOLOGICALS, SA (Rixensart, Belgium)
ASSIGNEE(S) GLAXOSMITHKLINE BIOLOGICALS S.A. (Rixensart, Belgium)
INVENTOR(S) David Burkhart (Research Triangle Park, North Carolina);  Michael Cochran (Research Triangle Park, North Carolina);  Christopher W Cluff (Research Triangle Park, North Carolina);  Daniel Larocque (Research Triangle Park, North Carolina);  Helene G Bazin-Lee (Research Triangle Park, North Carolina);  Julien St Jean (Research Triangle Park, North Carolina)
ABSTRACT The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
FILED Wednesday, March 09, 2016
APPL NO 15/556520
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/522 (20130101)
A61K 39/39 (20130101) Original (OR) Class
A61K 2039/555 (20130101)
A61K 2039/627 (20130101)
A61K 2039/55511 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646568 Wall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF TENESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
ASSIGNEE(S) UNIVERSITY OF TENESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S) Jonathan S Wall (Knoxville, Tennessee);  Stephen J Kennel (Kingston, Tennessee);  James S Foster (Knoxville, Tennessee)
ABSTRACT Disclosed are methods and compositions for targeting antibodies to amyloid deposits. For example, amyloid-reactive peptides that bind amyloid deposits are administered to a subject. Antibodies to the amyloid-reactive peptides are then administered to the subject. Upon administration of the antibodies, the amyloid-reactive peptides bind the antibodies and thus pre-target the antibodies to the amyloid deposits. In other examples, an amyloid-reactive fusion peptide contains an epitope of a known antibody. When the fusion peptide is administered to a subject, the fusion peptide binds amyloids in the subject. Administration to the subject of the known antibody that binds the epitope of the fusion peptide then targets the antibody to the amyloid deposit to which the fusion peptide is bound.
FILED Monday, July 16, 2018
APPL NO 16/036900
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1716 (20130101)
A61K 39/395 (20130101)
A61K 39/39583 (20130101) Original (OR) Class
A61K 47/66 (20170801)
A61K 47/6891 (20170801)
A61K 51/10 (20130101)
A61K 2039/505 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 14/4711 (20130101)
C07K 16/18 (20130101)
C07K 2317/34 (20130101)
C07K 2319/00 (20130101)
C07K 2319/70 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/6896 (20130101)
G01N 2333/4709 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646570 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
INVENTOR(S) Jin Xie (Athens, Georgia);  Hongmin Chen (Athens, Georgia);  Geoffrey D. Wang (Athens, Georgia)
ABSTRACT Photodynamic therapy systems comprising a nanoparticle that emits electromagnetic radiation having a first wavelength when irradiated with electromagnetic radiation, a photosensitizer which absorbs electromagnetic radiation of said first wavelength and a biocompatible mesoporous material are disclosed herein. In some examples, the photodynamic therapy system comprises a core comprising the nanoparticle, a first shell comprising the biocompatible mesoporous material, and a photosensitizer embedded in the first shell. Upon irradiation by, for example, X-rays, the nanoparticle can function as a transducer, converting X-ray photons to visible photons, and in turn, activating the photosensitizers. Methods of using the photodynamic therapy system are also disclosed.
FILED Thursday, June 18, 2015
APPL NO 15/320078
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/008 (20130101) Original (OR) Class
A61K 41/0057 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
A61N 5/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646580 Murthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia);  Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia);  Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) Niren Murthy (Berkeley, California);  Eric Seth Gilbert (Decatur, Georgia);  Xinghai Ning (Athens, Georgia);  Mark Goodman (Atlanta, Georgia);  Bryan Stubblefield (Atlanta, Georgia)
ABSTRACT This disclosure relates to conjugates for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate under conditions such that the conjugate is transported across the bacterial cell wall. Typically, the conjugate comprises an oligosaccharide and a molecule of interest. In certain embodiments, the molecule of interest may be a tracer or an antibiotic.
FILED Thursday, November 02, 2017
APPL NO 15/801892
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 45/06 (20130101)
A61K 47/61 (20170801) Original (OR) Class
A61K 49/0021 (20130101)
A61K 49/0032 (20130101)
A61K 49/0054 (20130101)
A61K 51/06 (20130101)
A61K 51/065 (20130101)

Polysaccharides; Derivatives Thereof
C08B 31/00 (20130101)

Compositions of Macromolecular Compounds
C08L 3/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646588 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Chicago, Illinois)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Zhijian Wu (Gaithersburg, Maryland);  Anand Swaroop (Gaithersburg, Maryland);  Suddhasil Mookherjee (Rockville, Maryland);  Suja Hiriyanna (Boyds, Maryland)
ABSTRACT Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
FILED Friday, March 11, 2016
APPL NO 15/556746
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101)
A61K 48/005 (20130101) Original (OR) Class

Peptides
C07K 14/4706 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/001 (20130101)
C12N 2830/008 (20130101)
C12N 2830/42 (20130101)
C12N 2830/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646590 Eberwine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) James Eberwine (Philadelphia, Pennsylvania);  Philip G. Haydon (Narberth, Pennsylvania);  Jai-Yoon Sul (Bensalem, Pennsylvania);  Hajime Takano (Lawrenceville, New Jersey);  Chia-Wen Kitty Wu (Philadelphia, Pennsylvania);  Fanyi Zeng (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) James Eberwine (Philadelphia, Pennsylvania);  Philip G. Haydon (Narberth, Pennsylvania);  Jai-Yoon Sul (Bensalem, Pennsylvania);  Hajime Takano (Lawrenceville, New Jersey);  Chia-Wen Kitty Wu (Philadelphia, Pennsylvania);  Fanyi Zeng (Philadelphia, Pennsylvania)
ABSTRACT The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the transfected cell.
FILED Tuesday, December 12, 2006
APPL NO 12/086471
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0083 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)
C12N 15/87 (20130101)
C12N 15/1079 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646591 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Xiaoyuan Chen (Potomac, Maryland);  Seulki Lee (Baltimore, Maryland);  Lei Zhu (Xiamen, China PRC)
ABSTRACT Disclosed are imaging agents having the following Formula I:
wherein F is a near infrared fluorophore, S is an enzymatically cleavable oligopeptide, Q is a fluorescence quencher molecule, and M is a moiety selected from the group consisting of PEG or derivative thereof and a targeting ligand, and wherein F, Q and M are linked to separate amino acids of the enzymatically cleavable oligopeptide. Compositions comprising such compounds, as well as methods of use, methods of identifying a cell or a population of cells in vivo expressing a protease of interest, and methods of treating a disease through imaging are also disclosed.
FILED Friday, October 28, 2016
APPL NO 15/337461
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/65 (20170801)
A61K 49/0032 (20130101) Original (OR) Class
A61K 49/0054 (20130101)
A61K 49/0056 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646614 Grinstaff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Mark W. Grinstaff (Brookline, Massachusetts);  Cynthia Ghobril (Reyersviller, France);  Michel Christophe Wathier (Allston, Massachusetts);  Marlena Dagmara Konieczynska (Lawrenceville, New Jersey)
ABSTRACT The inventions provided herein relate to dissolvable hydrogel compositions and methods of uses, e.g., but not limited to, in wound management. Accordingly, methods for wound management involving the dissolvable hydrogel compositions are also provided herein. In some embodiments, the dissolvable hydrogel composition comprises an adhesive thioester hydrogel, which can facilitate adherence of the dissolvable hydrogen composition to a surface (e.g., a wound) and can be controllably dissolved later upon addition of a thiolate compound to release the dissolvable hydrogel composition from the surface (e.g., the wound).
FILED Wednesday, May 09, 2018
APPL NO 15/975132
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/44 (20130101)
A61L 15/60 (20130101)
A61L 15/64 (20130101)
A61L 24/0015 (20130101)
A61L 24/0031 (20130101)
A61L 24/0042 (20130101)
A61L 26/008 (20130101) Original (OR) Class
A61L 26/009 (20130101)
A61L 26/0028 (20130101)
A61L 26/0066 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646617 Romero-Ortega et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Mario I. Romero-Ortega (Coppell, Texas);  Parisa Lotfi (Houston, Texas);  Benjamin R. Johnston (Arlington, Texas);  Swarupnarayan Dash (Arlington, Texas);  Joselito Razal (Wollongong, Australia);  Gordon Wallace (Wollongong, Australia)
ABSTRACT In one aspect, apparatuses for providing chemical gradients are described herein. In some embodiments, an apparatus described herein comprises a conduit having a first end and a second end, one or more microchannels disposed in the conduit and extending from the first end toward the second end, and a fiber coiled around the exterior of at least one microchannel, wherein the fiber comprises an active agent that is operable to diffuse into the interior of the microchannel.
FILED Monday, March 05, 2018
APPL NO 15/911738
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101) Original (OR) Class
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/20 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 2430/32 (20130101)

Compositions of Macromolecular Compounds
C08L 5/12 (20130101)
C08L 67/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646650 Cinar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Ali Cinar (Wilmette, Illinois);  Kamuran Turksoy (Chicago, Illinois);  Iman Hajizadeh (Chicago, Illinois)
ASSIGNEE(S) ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois)
INVENTOR(S) Ali Cinar (Wilmette, Illinois);  Kamuran Turksoy (Chicago, Illinois);  Iman Hajizadeh (Chicago, Illinois)
ABSTRACT Methods and modules for using physiological (biometric) variables to advance the state of the artificial pancreas. The method and system includes one or more modules for recursive model identification, hypoglycemia early alert and alarm, adaptive control, hyperglycemia early alert and alarm, plasma insulin concentration estimation, assessment of physical activity (e.g., presence, type, duration, expected effects on insulin sensitivity and GC), detection of acute stress and assessment of its impact on insulin sensitivity, detection of sleep and its stages and assessment of sleep stages on GC, sensor fault detection and diagnosis, software and controller performance evaluation and adjustment and/or pump fault detection and diagnosis.
FILED Thursday, June 02, 2016
APPL NO 15/171355
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7275 (20130101)
A61B 5/14503 (20130101)
A61B 5/14532 (20130101)
A61B 2560/0276 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/142 (20130101)
A61M 5/1723 (20130101) Original (OR) Class
A61M 2005/14208 (20130101)
A61M 2205/50 (20130101)
A61M 2205/3523 (20130101)
A61M 2230/201 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/63 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646685 Rea et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Rensselaer Polytechnic Institute (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Mark S. Rea (Melrose, New York);  Mariana Gross Figueiro (Troy, New York);  Martin B. Overington (Germantown, New York);  Jean Paul Freyssinier (Troy, New York);  Robert White (Niles, Michigan)
ABSTRACT Multipurpose lighting systems and methods of providing controllable lighting are provided. A lighting system includes a sheet of flexible material, a plurality of light sources and a controller. The plurality of light sources are attached to the sheet of flexible material and configured to emit diffused light. The controller is coupled to the plurality of light sources and is configured to control one or more of the plurality of light sources according to one of a plurality of prescribed lighting characteristics associated with a respective plurality of different lighting tasks. In some examples, the lighting system includes a camera coupled to the sheet of flexible material configured to capture at least one image of an object synchronously with the light emitted by the plurality of light sources.
FILED Tuesday, December 02, 2014
APPL NO 15/309571
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 11/00 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/0044 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0618 (20130101)
A61N 2005/0626 (20130101)
A61N 2005/0637 (20130101)
A61N 2005/0652 (20130101)
A61N 2005/0662 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 33/086 (20130101)
H05B 33/0842 (20130101)
H05B 37/0281 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 20/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646723 Reich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Daniel H. Reich (Baltimore, Maryland);  Collin L. Broholm (Ellicott City, Maryland);  David Zee (Ellicott City, Maryland);  Dale Roberts (Halethorpe, Maryland);  Michael C. Schubert (Parkton, Maryland);  Jorge Otero-Millan (Baltimore, Maryland);  Bryan Ward (Baltimore, Maryland)
ABSTRACT The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.
FILED Friday, August 04, 2017
APPL NO 15/668896
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/02 (20130101)
A61N 2/004 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646824 Yelvington et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Mainstream Engineering Corporation (Rockledge, Florida)
ASSIGNEE(S) Mainsteam Engineering Corporation (Rockledge, Florida)
INVENTOR(S) Paul E. Yelvington (Rockledge, Florida);  Alex Paulsen (Rockledge, Florida);  Andrew Carpenter (Rockledge, Florida);  Tyler Kunsa (Melbourne, Florida);  Ted Amundsen (Satellite Beach, Florida);  Nicholas Schwartz (Rockledge, Florida)
ABSTRACT A catalytic cookstove, for use in cooking, heating, and lighting, is disclosed for reducing particulate matter and carbon monoxide emissions. A non-platinum group metal catalyst promotes oxidation of particulate matter and carbon monoxide to produce carbon dioxide. Additionally, a passive damper automatically adjusts the fuel-to-air ratio based upon the size of fuel fed to the stove to ensure catalyst light off.
FILED Tuesday, June 12, 2018
APPL NO 16/005897
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Separation
B01D 53/864 (20130101) Original (OR) Class
B01D 2201/62 (20130101)
B01D 2255/2022 (20130101)
B01D 2255/20707 (20130101)
B01D 2257/502 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101)
B01J 23/04 (20130101)
B01J 35/04 (20130101)

Domestic Stoves or Ranges for Solid Fuels; Implements for Use in Connection With Stoves or Ranges
F24B 1/08 (20130101)
F24B 1/1895 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647037 Rodriguez et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
INVENTOR(S) Jennifer N. Rodriguez (Lathrop, California);  Duncan J. Maitland (College Station, Texas);  Thomas S. Wilson (San Leandro, California)
ABSTRACT Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
FILED Tuesday, August 09, 2016
APPL NO 15/232619
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/5663 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2075/00 (20130101)
B29K 2105/046 (20130101)
B29K 2995/0093 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/18 (20130101)
B32B 5/32 (20130101)
B32B 2266/08 (20130101)
B32B 2266/0278 (20130101)
B32B 2535/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/3228 (20130101)
C08G 18/3278 (20130101)
C08G 18/3284 (20130101)
C08G 2101/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/38 (20130101)
C08J 2205/052 (20130101)
C08J 2207/10 (20130101)
C08J 2375/04 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647658 Verdin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The J. David Gladstone Institutes (San Francisco, California);  The Regents of the University of California (Oakland, California);  Ithaca College (Ithaca, New York)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California);  The Regents of The University Of California (Oakland, California);  Ithaca College (Ithaca, New York)
INVENTOR(S) Eric Verdin (Mill Valley, California);  Scott Michael Ulrich (Brooktondale, New York);  John C. Newman (San Francisco, California)
ABSTRACT Aspects of the present disclosure include fatty acid β-hydroxyester compounds (e.g., fatty acid esters of β-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid β-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
FILED Wednesday, July 31, 2019
APPL NO 16/528524
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 33/12 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)
A23V 2200/322 (20130101)
A23V 2250/54 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/23 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 13/12 (20180101)
A61P 25/08 (20180101)
A61P 25/16 (20180101)
A61P 25/28 (20180101)
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 69/34 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647664 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina);  University of North Carolina (Chapel Hill, North Carolina)
INVENTOR(S) Pei Zhou (Cary, North Carolina);  Eric J. Toone (Durham, North Carolina);  Robert A. Nicholas (Chapel Hill, North Carolina)
ABSTRACT Disclosed are compounds of formulae: (I), and (II) and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R21, R22, R23, R34, R37, R33, R39, D, Q, Y, X, X1, X3, and X4 are defined herein. These compounds are useful for treating Gram-negative bacteria infections.
FILED Monday, August 18, 2014
APPL NO 14/912134
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/5375 (20130101)

Acyclic or Carbocyclic Compounds
C07C 259/06 (20130101) Original (OR) Class
C07C 317/44 (20130101)

Heterocyclic Compounds
C07D 213/64 (20130101)
C07D 231/12 (20130101)
C07D 295/135 (20130101)
C07D 295/155 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/47 (20180101)
Y02A 50/402 (20180101)
Y02A 50/473 (20180101)
Y02A 50/475 (20180101)
Y02A 50/481 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647671 Wuest
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) William M. Wuest (Wallingford, Pennsylvania)
ABSTRACT The present invention includes novel analogs of promysalin useful in preventing or treating a microbial infection. The present invention also includes methods preventing or treating a microbial infection in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention.
FILED Tuesday, April 18, 2017
APPL NO 16/091685
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/401 (20130101)
A61K 31/401 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Heterocyclic Compounds
C07D 207/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647709 Thatcher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Gregory R. J. Thatcher (Chicago, Illinois);  Isaac Thomas Schiefer (Chicago, Illinois);  Ottavio Arancio (New York, New York);  Mauro Fa (New York, New York)
ABSTRACT The invention provides for novel cysteine protease inhibitors and compositions comprising novel cysteine protease derivatives. The invention further provides for methods for treatment of neurodegenerative diseases comprising administration novel cysteine protease inhibitors or compositions comprising novel cysteine protease inhibitors. In some embodiments, the cysteine protease inhibitors are calpain inhibitors.
FILED Friday, June 24, 2016
APPL NO 15/192113
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 303/48 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)
C07D 417/12 (20130101) Original (OR) Class
C07D 417/14 (20130101)
C07D 495/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647725 Sucheck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The University of Toledo (Toledo, Ohio);  Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio);  Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Steven Sucheck (Toledo, Ohio);  Sandeep Thanna (Toledo, Ohio);  Richard Slayden (Fort Collins, Colorado)
ABSTRACT 2-Aminothiophene derivatives, uses of the same, and methods of making the same, are described.
FILED Friday, April 21, 2017
APPL NO 16/094770
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/06 (20180101)

Heterocyclic Compounds
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647743 Horne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) William Seth Horne (Madison, Wisconsin);  Samuel H. Gellman (Madison, Wisconsin);  Lisa M. Johnson (Marshall, Minnesota)
ABSTRACT Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising α-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the α-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with β-amino acid residues, and the α-amino acid residues are distributed in a repeating pattern.
FILED Wednesday, March 06, 2013
APPL NO 13/786673
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/006 (20130101) Original (OR) Class
C07K 1/107 (20130101)
C07K 7/02 (20130101)
C07K 14/00 (20130101)
C07K 14/001 (20130101)
C07K 14/005 (20130101)
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647748 Kong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Leopold Kong (Bethesda, Maryland);  Ian A. Wilson (La Jolla, California);  Natalia De Val (San Diego, California);  Andrew B. Ward (San Diego, California);  Dennis Burton (La Jolla, California);  Linling He (San Diego, California);  Jiang Zhu (San Diego, California)
ABSTRACT The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
FILED Wednesday, October 31, 2018
APPL NO 16/176200
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 47/64 (20170801)
A61K 47/6929 (20170801)
A61K 2039/645 (20130101)
A61K 2039/5258 (20130101)
A61K 2039/6031 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647754 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Weizao Chen (Frederick, Maryland);  Prabakaran Ponraj (Frederick, Maryland)
ABSTRACT The invention provides a polypeptide comprising a single domain CD4, as well as a fusion protein comprising the single domain CD4 and one or more fusion partners. A nucleic acid encoding the polypeptide or fusion protein, as well as compositions or cells comprising the polypeptide, fusion protein, or nucleic acid also are provided.
FILED Monday, October 16, 2017
APPL NO 15/784988
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/162 (20130101)
A61K 38/1774 (20130101)
A61K 47/6425 (20170801)

Peptides
C07K 14/70514 (20130101) Original (OR) Class
C07K 16/1063 (20130101)
C07K 2319/00 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647960 Eberwine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) James Eberwine (Philadelphia, Pennsylvania);  Jai-Yoon Sul (Bensalem, Pennsylvania);  Chia-Wen Wu (Philadelphia, Pennsylvania);  Fanyi Zeng (Philadelphia, Pennsylvania);  Junhyong Kim (Narbeth, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) James Eberwine (Philadelphia, Pennsylvania);  Jai-Yoon Sul (Bensalem, Pennsylvania);  Chia-Wen Wu (Philadelphia, Pennsylvania);  Fanyi Zeng (Philadelphia, Pennsylvania);  Junhyong Kim (Narbeth, Pennsylvania)
ABSTRACT The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
FILED Tuesday, April 06, 2010
APPL NO 12/755277
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/062 (20130101) Original (OR) Class
C12N 5/0622 (20130101)
C12N 5/0657 (20130101)
C12N 2501/998 (20130101)
C12N 2506/00 (20130101)
C12N 2506/08 (20130101)
C12N 2506/1307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647961 Cohen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota);  UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  University of Washington (Seattle, Washington)
INVENTOR(S) Peter A. Cohen (Scottsdale, Arizona);  Sandra J. Gendler (Scottsdale, Arizona);  Latha B. Pathangey (Scottsdale, Arizona);  Dustin B. McCurry (Phoenix, Arizona);  Jessica E. Gorman (Scottsdale, Arizona);  Mary L. Disis (Renton, Washington)
ABSTRACT This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
FILED Friday, August 12, 2016
APPL NO 15/754216
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 2039/5158 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 2501/22 (20130101)
C12N 2501/51 (20130101)
C12N 2501/515 (20130101)
C12N 2501/2307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647964 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
NIH Office of the Director (NIHOD)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Board of Regents of the University of Nebraska (Lincoln, Nebraska);  Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Board of Regents of the University of Nebraska (Lincoln, Nebraska);  Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Gregory A. Smith (Oak Park, Illinois);  Patricia Jane Sollars (Lincoln, Nebraska);  Gary Edward Pickard (Lincoln, Nebraska);  Ekaterina E. Heldwein (Belmont, Massachusetts)
ABSTRACT Provided herein are compositions and methods for vaccination and research applications. In particular, provided herein are non-neuroinvasive herpesviruses and alpha herpesviruses and uses thereof.
FILED Friday, March 04, 2016
APPL NO 15/555873
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/763 (20130101)
A61K 39/12 (20130101)
A61K 39/25 (20130101)
A61K 39/245 (20130101)
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 2299/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2710/16034 (20130101)
C12N 2710/16621 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16632 (20130101)
C12N 2710/16633 (20130101)
C12N 2710/16634 (20130101)
C12N 2710/16643 (20130101)
C12N 2710/16721 (20130101)
C12N 2710/16722 (20130101)
C12N 2710/16732 (20130101)
C12N 2710/16733 (20130101)
C12N 2710/16734 (20130101)
C12N 2710/16743 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647983 Krainer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
ASSIGNEE(S) Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S) Adrian Krainer (Huntington Station, New York);  Isabel Aznarez (Queens, New York);  Tomoki Nomakuchi (Syosset, New York)
ABSTRACT The present disclosure relates to compositions and methods for inhibiting nonsense-mediated mRNA decay in a gene-specific manner, for example in the treatment of diseases or disorders caused by nonsense mutations.
FILED Thursday, September 04, 2014
APPL NO 14/916561
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/726 (20130101)
A61K 31/4245 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2320/30 (20130101)
C12N 2320/31 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648000 Hauswirth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) William W. Hauswirth (Gainesville, Florida);  Sanford L. Boye (Gainesville, Florida);  Daniel M. Lipinski (Milwaukee, Wisconsin);  Michael E. Boulton (Chelsea, Alabama);  Shannon E. Boye (Gainesville, Florida)
ABSTRACT Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian vascular system, and complications from Type I diabetes. Also disclosed are methods for systemic and tissue-localized delivery of therapeutic rAAV-based gene expression cassettes to vascular endothelial cells, tissues, and organs, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications including the treatment of vasculitis, and complications arising from Type I diabetes, such as macular edema, nephropathy, diabetic retinopathy, and the like.
FILED Tuesday, February 16, 2016
APPL NO 15/550864
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/50 (20130101)
A61K 48/0058 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/78 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14121 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/008 (20130101)
C12N 2830/15 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 305/04016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648002 Webber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Beau R. Webber (Minneapolis, Minnesota);  Mark J. Osborn (Minneapolis, Minnesota);  Jakub Tolar (Minneapolis, Minnesota);  Bruce R. Blazar (Golden Valley, Minnesota)
ABSTRACT Methods of gene correction, methods of generating induced pluripotent stem cells (iPSCs), and methods of deriving multi-lineage cell types with therapeutic value. In some embodiments, the gene correction affects the expression and/or function of the functional type VII collagen protein (C7).
FILED Wednesday, November 22, 2017
APPL NO 15/820653
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/78 (20130101)
C07K 2319/81 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0629 (20130101)
C12N 5/0647 (20130101)
C12N 5/0652 (20130101)
C12N 5/0656 (20130101)
C12N 5/0696 (20130101)
C12N 15/102 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2500/38 (20130101)
C12N 2500/90 (20130101)
C12N 2501/155 (20130101)
C12N 2501/727 (20130101)
C12N 2502/28 (20130101)
C12N 2506/45 (20130101)
C12N 2506/1307 (20130101)
C12N 2510/00 (20130101)
C12N 2533/54 (20130101)
C12N 2760/18843 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648012 Akabas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Myles Akabas (Scarsdale, New York);  Ithiel James Frame (Bronx, New York);  Roman Deniskin (Bronx, New York)
ABSTRACT Methods and systems for identifying inhibitors of Equilibrative Nucleoside Transporters are provided. Methods and systems for identifying inhibitors of Concentrative Nucleoside Transporters are also provided.
FILED Wednesday, January 08, 2014
APPL NO 14/759973
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/44 (20130101)
C07K 14/445 (20130101)
C07K 14/705 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)
C12Q 1/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648014 Parker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Laurie L Parker (Minneapolis, Minnesota);  Robert John Schuster (West Lafayette, Indiana)
ABSTRACT Disclosed are compositions and methods for measuring tyrosine kinase activity using degradation resistant biosensors comprising a reporter sequence, a target sequence, and a transduction sequence. In certain embodiments, the invention includes a biosensor comprising a peptide comprising a reporter sequence, i.e., an amino acid sequence including a tyrosine residue that can be phosphorylated by a tyrosine kinase. In certain embodiments, a biosensor comprises a reporter sequence configured to resist degradation from proteases, a targeting sequence coupled to the reporter sequence and configured to bind to a protein interaction domain of a kinase, and a transduction sequence coupled to the targeting sequence.
FILED Wednesday, April 29, 2015
APPL NO 15/309002
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2440/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648020 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Bernd Zetsche (Gloucester, Massachusetts);  Jonathan S. Gootenberg (Cambridge, Massachusetts);  Omar O Abudayyeh (Boston, Massachusetts);  Ian Slaymaker (Cambridge, Massachusetts)
ABSTRACT The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. Methods for making and using and uses of such systems, methods, and compositions and products from such methods and uses are also disclosed and claimed.
FILED Sunday, December 17, 2017
APPL NO 15/844608
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6832 (20130101) Original (OR) Class
C12Q 2521/301 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648033 Khatri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Purvesh Khatri (Menlo Park, California);  Timothy E. Sweeney (San Francisco, California)
ABSTRACT Biomarkers and methods of using them for aiding diagnosis, prognosis, and treatment of critically ill patients are disclosed. In particular, the invention relates to the use of biomarkers for prognosis of mortality in critically ill patients with sepsis, severe trauma, or burns.
FILED Monday, May 20, 2019
APPL NO 16/417358
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2537/165 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/06 (20130101)
C40B 40/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/6893 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648035 Agarwal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Rachana Agarwal (Ellicott City, Maryland);  Stephen J. Meltzer (Lutherville, Maryland)
ABSTRACT The present invention relates to the field of gastric cancer. More specifically, the present invention provides methods and compositions for diagnosing and treating gastric cancer. In a specific embodiment, a method for diagnosing gastric cancer or a likelihood thereof in a patient comprises the steps of (a) providing a sample from the patient; (b) measuring the methylation levels of one or more biomarkers in the sample collected from the patient; and (c) predicting gastric cancer in the patient if the biomarkers are hypermethylated. In a more specific embodiment, the one or more biomarkers comprises tight junction protein claudin-1 1 (CLD-N11), the transcription factor BarH-like homeobox (BARX1), basonuclin1 (BNC1), Coagulation factor C homolog (COCH), filamin C gamma (FLNC), cytoglobin B (CYGB), glutamine-fructose-6-phospahe-transaminase-2 (GFPT2), heat-shock-70 kDa protein-6 (HSPA6), snail homolog 1 (SNAL1), skin calmodulin-related factor (SCARF), and tumor protein p53 binding protein 2 (TP53BP2).
FILED Tuesday, November 26, 2013
APPL NO 14/646774
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/154 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57446 (20130101)
G01N 2440/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648040 Mulé et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
ASSIGNEE(S) H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
INVENTOR(S) James J. Mulé (Odessa, Florida);  Domenico Coppola (Tampa, Florida);  Timothy J. Yeatman (Thonotosassa, Florida);  Audrey Loboda (Philadelphia, Pennsylvania);  Michael V. Nebozhyn (Yeadon, Pennsylvania)
ABSTRACT This invention relates to methods for treating subjects with breast cancer, based on tumor expression levels of chemokines.
FILED Friday, July 06, 2018
APPL NO 16/029499
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/57407 (20130101)
G01N 33/57415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648917 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Jimin Peter Kim (State College, Pennsylvania);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing includes disposing a fluorophore in a biological environment, wherein the fluorophore includes a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further includes exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, includes hydrogen ions, halide ions, and/or halogens.
FILED Wednesday, April 06, 2016
APPL NO 15/564561
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 57/00 (20130101)
C09B 69/109 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1018 (20130101)
C09K 2211/1466 (20130101)
C09K 2211/1483 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 21/77 (20130101) Original (OR) Class
G01N 21/6428 (20130101)
G01N 31/16 (20130101)
G01N 31/221 (20130101)
G01N 2021/6432 (20130101)
G01N 2021/7786 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/19 (20150115)
Y10T 436/145555 (20150115)
Y10T 436/173845 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648966 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Peixuan Guo (Lexington, Kentucky);  Shaoying Wang (Lexington, Kentucky)
ABSTRACT A conductive channel-containing membrane includes a membrane layer, and a SPP1 connector polypeptide variant that is incorporated into the membrane layer to form an aperture through which conductance can occur when an electrical potential is applied across the membrane. A method of sensing a molecule, such as a polypeptide or nucleic acid molecule, makes use of the conductive channel-containing membrane. A method of DNA sequence makes use of the conductive channel-containing membrane.
FILED Friday, January 15, 2016
APPL NO 15/543821
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2795/10322 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44791 (20130101)
G01N 33/48721 (20130101) Original (OR) Class
G01N 2333/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648977 Walston et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Aging (NIA)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Jeremy D. Walston (Baltimore, Maryland);  Peter M. Abadir (Woodstock, Maryland);  Alka Jain (Columbia, Maryland);  Neal Fedarko (Columbia, Maryland)
ABSTRACT The invention described herein provides methods for treating a disease or disorder associated with angiotensin receptor signaling in a patient exhibiting elevated levels of ATIR autoantibodies. The invention also provides methods of identifying a patient suffering from a disease or disorder associated with angiotensin receptor signaling that may benefit from treatment with an angiotensin receptor blocker. Patients with elevated levels of ATIR autoantibodies are identified as candidates that particularly benefit from treatment with an angiotensin receptor blocker.
FILED Friday, October 28, 2016
APPL NO 15/769617
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/41 (20130101)
A61K 31/513 (20130101)
A61K 31/4178 (20130101)
A61K 31/4184 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648982 Kalkum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Markus Kalkum (Azusa, California);  Karine Bagramyan (North Hollywood, California);  Diana Diaz-Arevalo (Monrovia, California);  James I. Ito (La Verne, California);  Sanjeet Dadwal (Duarte, California)
ABSTRACT Provided herein are methods for detecting an Aspergillus protease in a sample, diagnosing a subject with aspergillosis caused by an Aspergillus infection based on the presence of an Aspergillus protease in a sample, and methods of aspergillosis treatment that incorporate these diagnostic methods. In certain embodiments, the Aspergillus protease is Asp f2, and the Aspergillus infection is caused A. fumigatus, A. flavus, A. versicolor, A. niger, or A. terreus. Also provided herein are antibodies and kits for use in these methods, including novel antibodies specific for Asp f2.
FILED Monday, August 15, 2016
APPL NO 15/236988
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/04 (20130101)
A61K 38/06 (20130101)
A61K 38/07 (20130101)
A61K 38/10 (20130101)
A61K 38/16 (20130101)
A61K 39/0002 (20130101)

Peptides
C07K 16/14 (20130101)
C07K 16/40 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/37 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101) Original (OR) Class
G01N 33/577 (20130101)
G01N 33/54313 (20130101)
G01N 33/56961 (20130101)
G01N 2333/38 (20130101)
G01N 2333/962 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649053 Hu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peng Hu (Beverly Hills, California)
ABSTRACT Disclosed herein are methods and systems for clinical practice of medical imaging on patients with metal-containing devices, such as implanted cardiac devices. In particular, Disclosed herein are methods and systems for improved late gadolinium enhancement (LGE) MRI for assessing myocardial viability for patients with implanted cardiac devices, i.e., cardiac pacemakers and implantable cardiac defibrillators.
FILED Friday, November 01, 2013
APPL NO 14/440346
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/044 (20130101)
A61B 5/055 (20130101)
A61B 5/02028 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/103 (20130101)
A61K 49/105 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5601 (20130101)
G01R 33/5602 (20130101) Original (OR) Class
G01R 33/5635 (20130101)
G01R 33/56325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649914 Caccamo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Marco Caccamo (Urbana, Illinois);  Rodolfo Pellizzoni (Waterloo, Canada);  Renato Mancuso (Urbana, Illinois);  Rohan Tabish (Urbana, Illinois);  Saud Wasly (Jeddah, Saudi Arabia)
ABSTRACT An embodiment may involve determining that a first logical partition of a scratchpad memory coupled to a processor core is empty and a first application is scheduled to execute; instructing a direct memory access (DMA) engine to load the first application into the first logical partition and then instructing the processor core to execute the first application from the first logical partition; while the first application is being executed from the first logical partition, determining that a second logical partition of the scratchpad memory is empty and a second application is scheduled to execute; instructing the DMA engine to load the second application into the second logical partition; determining that execution of the first application has completed; and instructing the DMA engine to unload the first application from the first logical partition and instructing the processor core to execute the second application from the second logical partition.
FILED Friday, June 30, 2017
APPL NO 15/639666
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 3/0611 (20130101)
G06F 3/0659 (20130101)
G06F 3/0683 (20130101)
G06F 9/5077 (20130101)
G06F 12/1081 (20130101) Original (OR) Class
G06F 13/30 (20130101)
G06F 2212/656 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650228 Roberson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David P. Roberson (Cambridge, Massachusetts);  Clifford J. Woolf (Newton, Massachusetts);  Michael T. Do (Brookline, Massachusetts);  Alexander B. Wiltschko (Brookline, Massachusetts);  Sandeep Robert Datta (Newton, Massachusetts)
ABSTRACT A device for detecting and recording animal behavior is provided. The device includes at least one corral that defines a contained field, the base surface of the at least one corral being sensitive to the animal's footprint. The device also includes an image capturing device that cooperates with the base surface to capture a first video frame in which at least one of a tail, body and head of the animal is illuminated by a light below the animal and a second video frame in which both a profile of a full footprint and a profile of a toe print of the animal when the animal is standing on its toes is illuminated by a light that is totally internally reflected within the base surface. A control system is arranged to control the image capturing device to capture the first and second video frames.
FILED Friday, September 16, 2016
APPL NO 15/760792
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 1/031 (20130101)
A01K 29/005 (20130101)

Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/112 (20130101)
A61B 5/165 (20130101)
A61B 5/1113 (20130101)
A61B 5/1118 (20130101)
A61B 5/4824 (20130101)
A61B 5/7267 (20130101)
A61B 2503/40 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/209 (20130101)
G06K 9/00335 (20130101)
G06K 9/00348 (20130101) Original (OR) Class
G06K 9/00362 (20130101)
G06K 9/2027 (20130101)
G06K 9/2036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650512 Hoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Benjamin A. Hoff (Ann Arbor, Michigan);  Craig Galban (Ann Arbor, Michigan);  Brian D. Ross (Ann Arbor, Michigan)
ABSTRACT Computer-implemented methods are used to analyze a medical image to assess the state of the sample region. In at least one embodiment, the method comprises receiving at least one medical image collected previously from an image source, the at least one medical image comprising a plurality of voxels, each characterized by a signal value; classifying the signal value of each voxel as representing one of healthy tissue or diseased tissue based on a threshold value; and analyzing at least one topographical feature of the at least one medical image.
FILED Wednesday, June 14, 2017
APPL NO 15/623151
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/60 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/30061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650515 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Satish Viswanath (Pepper Pike, Ohio);  Jacob Antunes (Cincinnati, Ohio);  Pallavi Tiwari (Shaker Heights, Ohio)
ABSTRACT Embodiments access an image of a region of interest (ROI) demonstrating cancerous pathology; extract radiomic features from the ROI; define a radiomic feature expression scene based on the ROI and radiomic features; generate a cluster map by superpixel clustering the expression scene; generate an expression map by repartitioning the cluster map into expression levels; compute a textural and spatial phenotypes for the expression map based on the expression levels; construct a radiomic spatial textural (RADISTAT) descriptor by concatenating the textural and spatial phenotypes; provide the RADISTAT descriptor to a machine learning classifier; receive, from the machine learning classifier, a first probability that the ROI is a responder or non-responder, or a second probability that the ROI will experience long-term survival or short-term survival, based, at least in part, on the RADISTAT descriptor; and generate a classification of the ROI as a responder or non-responder, or long-term survivor or short-term survivor.
FILED Wednesday, May 23, 2018
APPL NO 15/987137
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/52 (20130101)
G01N 2800/54 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5601 (20130101)
G01R 33/5602 (20130101)
G01R 33/5608 (20130101)
G01R 33/56341 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/1611 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/3241 (20130101)
G06K 9/6218 (20130101)
G06K 9/6267 (20130101)
G06K 2209/05 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10072 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650519 Parsey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Ramin Parsey (Mountain Lakes, New Jersey);  Arthur Mikhno (New City, New York)
ABSTRACT The subject matter disclosed herein relates to methods for diagnosing a neurological disorder in a subject. In certain aspects, the methods described herein involve determining one or more critical areas in the brain from PET data where two groups differ and measuring PET signal within determined critical areas in a new subject in order to assign risk or diagnosis.
FILED Tuesday, September 29, 2015
APPL NO 14/869862
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/165 (20130101)
A61B 5/4088 (20130101)
A61B 5/7275 (20130101)
A61B 6/037 (20130101)
A61B 6/56 (20130101)
A61B 6/501 (20130101)
A61B 6/563 (20130101)
A61B 6/5247 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/10 (20130101)
G01R 33/0023 (20130101)
G01R 33/481 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/52 (20130101)
G06K 9/6267 (20130101)
G06K 2009/4666 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/0014 (20130101) Original (OR) Class
G06T 7/0016 (20130101)
G06T 7/41 (20170101)
G06T 2200/04 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/20128 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652444 Horstmeyer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Roarke W. Horstmeyer (San Marino, California);  Guoan Zheng (Vernon, Connecticut);  Changhuei Yang (Alhambra, California)
ABSTRACT Certain embodiments pertain to Multiplexed Fourier Ptychographic imaging systems and methods. In one example, the Multiplexed Fourier Ptychographic imaging system includes an LED array configured to illuminate a sequence of LED patterns for illuminating a sample being imaged. The system includes LED circuitry configured to independently control power to turn on multiple LEDs simultaneously in each LED pattern of the array. The system has a light detector that acquires a first set of lower resolution images of the sample each image acquired during exposure time during illumination by a unique LED pattern. The system uses the first set of lower resolution images to generate a second set of lower resolution images associated with each LED in the LED array and iteratively updates overlapping regions in the Fourier domain with the second set of lower resolution images to generate a higher resolution image.
FILED Friday, December 04, 2015
APPL NO 14/960252
ART UNIT 2489 — Computer Networks
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/002 (20130101)
G02B 21/365 (20130101)
G02B 21/367 (20130101)
G02B 27/58 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00134 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 7/00 (20130101)

Pictorial Communication, e.g Television
H04N 5/265 (20130101)
H04N 5/2256 (20130101) Original (OR) Class
H04N 5/23229 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652527 Achilefu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Samuel Achilefu (St. Louis, Missouri)
ABSTRACT A compound of formula (I) is provided having the structure: cypate-cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH, and each amino acid is independently in a D or L configuration. Also provided are pharmaceutical compositions that include the compound of formula (I) and its use in treating cancer by administering it to a patient in need thereof.
FILED Tuesday, November 13, 2018
APPL NO 16/189551
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0005 (20130101)
A61B 1/0692 (20130101)
A61B 34/25 (20160201)
A61B 90/30 (20160201)
A61B 90/36 (20160201)
A61B 90/361 (20160201)
A61B 2090/364 (20160201)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0032 (20130101)
A61K 49/0034 (20130101)
A61K 49/0056 (20130101)

Peptides
C07K 7/06 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/017 (20130101)

Pictorial Communication, e.g Television
H04N 5/374 (20130101)
H04N 13/344 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE47983 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Thursday, June 28, 2018
APPL NO 16/022679
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10645924 Bertrand
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United States of America as represented by the Secretary of the Navy (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Jacques C Bertrand (Gainesville, Florida)
ABSTRACT The invention relates to compositions comprising one or more insecticides and further comprising a carrier composition comprising one or more glycols, and methods of controlling an insect population comprising applying said compositions to the insect habitat using a thermal fogger.
FILED Tuesday, April 18, 2017
APPL NO 15/489769
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/02 (20130101)
A01N 25/02 (20130101)
A01N 25/04 (20130101) Original (OR) Class
A01N 25/06 (20130101)
A01N 25/06 (20130101)
A01N 63/00 (20130101)
A01N 63/00 (20130101)
A01N 63/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646462 D'Agostino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Dominic Paul D'Agostino (Tampa, Florida);  Patrick Arnold (Champaign, Illinois);  Shannon Kesl (Long Beach, California)
ABSTRACT Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.
FILED Thursday, June 01, 2017
APPL NO 15/610668
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 2/52 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/22 (20130101)
A61K 31/22 (20130101)
A61K 31/23 (20130101) Original (OR) Class
A61K 31/23 (20130101)
A61K 31/047 (20130101)
A61K 31/047 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646985 Moan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brad Moan (Greenwood, Indiana);  Eric Scheid (Bloomington, Indiana)
ABSTRACT A method employing an apparatus in conjunction with a hammer-drill to penetrate composite metal and non-metal structure or structures including, for example, thick metal or rebar encountered during concrete, rock or masonry boring operations without requiring a change in drill equipment.
FILED Monday, September 12, 2016
APPL NO 15/262756
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Turning; Boring
B23B 51/00 (20130101)
B23B 51/02 (20130101)
B23B 51/0009 (20130101)
B23B 51/009 (20130101)
B23B 2226/75 (20130101)
B23B 2228/36 (20130101)
B23B 2231/02 (20130101)
B23B 2251/54 (20130101)
B23B 2251/60 (20130101)

Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/28 (20130101)

Percussive Tools
B25D 17/02 (20130101) Original (OR) Class
B25D 2217/0007 (20130101)

Working Stone or Stone-like Materials
B28D 1/146 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 10/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 408/906 (20150115)
Y10T 408/907 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647071 Sherman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armament Research, Development and Engineering Center (ARDEC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Powdermet, Inc. (Euclid, Ohio)
ASSIGNEE(S) Powdermet Inc. (Euclid, Ohio)
INVENTOR(S) Andrew Sherman (Mentor, Ohio);  Haixong Tang (Euclid, Ohio);  Brian Doud (Cleveland Heights, Ohio)
ABSTRACT A composite film having a high dielectric permittivity engineered particles dispersed in a high breakdown strength polymer material to achieve high energy density.
FILED Monday, October 17, 2016
APPL NO 15/294936
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/02 (20130101)
B29C 39/003 (20130101)
B29C 55/04 (20130101)
B29C 55/12 (20130101)
B29C 70/60 (20130101) Original (OR) Class
B29C 70/882 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/162 (20130101)
B29K 2509/02 (20130101)
B29K 2995/0006 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/34 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/12 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 4/18 (20130101)
H01G 4/32 (20130101)
H01G 4/33 (20130101)
H01G 4/186 (20130101)
H01G 4/206 (20130101)
H01G 4/306 (20130101)
H01G 4/1227 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647410 Higbie et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Aviation and Missile Center (CCDC AVMC)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Robert Higbie (Haslet, Texas);  David Littlejohn (Haslet, Texas)
ABSTRACT A spinner assembly includes a cone-shaped member having a plurality of blade openings. The cone-shaped member is receivable about a shaft at a first location. A bulkhead frame is connected to the cone-shaped member. At least one strut is configured to couple the bulkhead frame to the shaft at a second location. The at least one strut includes at least one arm having a longitudinal rigid member and at least one flexure region that defines an axis about which the at least one arm bends.
FILED Monday, August 01, 2016
APPL NO 15/225234
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 11/14 (20130101) Original (OR) Class
B64C 27/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647420 Kopanski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Krzysztof Kopanski (Trumbull, Connecticut);  Justin Thomas (New Haven, Connecticut)
ABSTRACT An aircraft rotor blade includes a surface of the rotor blade, at least one main hole that extends through the surface and has a width and a length, and at least one leader hole that extends through the surface and has a length that is less than the length of the main hole and arranged spaced from and adjacent the main hole. The leader hole gradually increases in width from a first end of the leader hole opposite the main hole to an opposed second end of the leader hole proximate the main hole to operatively gradually distribute stress in the leader and main holes and rotor blade and reduce an amount of the stress exerted therein.
FILED Thursday, October 15, 2015
APPL NO 15/533502
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/06 (20130101)
B64C 27/008 (20130101)
B64C 27/473 (20130101) Original (OR) Class
B64C 2027/4736 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647442 Alber
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Mark R. Alber (Milford, Connecticut)
ABSTRACT A vertical take-off and landing (VTOL) aircraft is provided and includes wings, first and second nacelles supported on each of the wings, each of the first and second nacelles including a propeller drivable to generate aircraft thrust, and an asymmetrical power generation unit. The asymmetrical power generation unit includes a single engine unit disposed in only one of the first and second nacelles to generate power to drive the propellers of both the first and second nacelles.
FILED Monday, November 16, 2015
APPL NO 15/543443
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/82 (20130101)
B64C 29/02 (20130101)
B64C 39/024 (20130101)
B64C 2201/028 (20130101)
B64C 2201/088 (20130101)
B64C 2201/104 (20130101)
B64C 2201/165 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/06 (20130101)
B64D 27/12 (20130101)
B64D 35/04 (20130101) Original (OR) Class

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647758 Wilson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) James M. Wilson (Philadelphia, Pennsylvania);  Anna Tretiakova (Woburn, Massachusetts)
ABSTRACT A recombinant adeno-associated virus (AAV) having an AAV capsid and packaged therein a heterologous nucleic acid which expresses two functional antibody constructs in a cell is described. Also described are antibodies comprising a heavy chain and a light chain from a heterologous antibody. In one embodiment, the antibodies are co-expressed from a vector containing: a first expression cassette which encodes at least a first open reading frame (ORF) for a first immunoglobulin under the control of regulatory control sequences which direct expression thereof; and a second expression cassette which comprises a second ORF, a linker, and a third ORF under the control of regulatory control sequences which direct expression thereof, wherein the second and third ORF for a second and third immunoglobulin construct. The vector co-expressing these two antibody constructs is in one embodiment an AAV, in which the 5′ and 3′ ITRs flank the expression cassettes and regulatory sequences.
FILED Tuesday, July 02, 2019
APPL NO 16/460623
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0008 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 16/1018 (20130101) Original (OR) Class
C07K 2317/14 (20130101)
C07K 2317/31 (20130101)
C07K 2317/51 (20130101)
C07K 2317/52 (20130101)
C07K 2317/515 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2750/14121 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/30 (20130101)
C12N 2830/50 (20130101)
C12N 2830/205 (20130101)
C12N 2840/203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647878 Webster et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Dean C. Webster (Fargo, North Dakota);  Teluka Galhenage (Fargo, North Dakota)
ABSTRACT The invention is directed to curable polyurethane coating compositions which may be used to form fouling release coatings, e.g., for use in protecting boat hulls. The curable polyurethane coating compositions of the invention comprise (a) a prepolymer made by reacting at least one polyisocyanate with (i) at least one monocarbinol-terminated poly(dimethylsiloxane), (ii) at least one methoxy-terminated poly(ethylene glycol), or (iii) mixtures thereof, (b) at least one polyol, and (c) at least one polyisocyanate crosslinker. The invention also relates to the prepolymer used in the curable coating compositions. The invention further relates to methods for reducing or preventing biofouling of a surface exposed to an aqueous environment comprising the steps of coating the surface with a curable coating composition of the invention to form a coated surface, and curing the coating coating composition on the coated surface.
FILED Wednesday, June 01, 2016
APPL NO 15/576399
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/283 (20130101)
C08G 18/289 (20130101)
C08G 18/725 (20130101)
C08G 18/755 (20130101)
C08G 18/792 (20130101)
C08G 18/6229 (20130101)
C08G 18/8064 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1637 (20130101)
C09D 175/04 (20130101)
C09D 175/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647998 Wilson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) James M. Wilson (Philadelphia, Pennsylvania);  Anna Tretiakova (Philadelphia, Pennsylvania)
ABSTRACT Described herein are synonymously altered gene sequences which express protein in differing levels within secretory as compared to non-secretory target tissue. An expression cassette comprising an open reading frame (ORF) for a protein under the control of regulatory sequences which direct expression of the product in cell, which ORF has been modified to preferentially increase expression levels in a selected tissue, wherein the modified ORF is characterized by a triplet frequency of any one of Tables 3-12, 16 or 17.
FILED Tuesday, June 20, 2017
APPL NO 15/627805
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
C12N 2800/22 (20130101)
C12N 2830/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648006 Arnold et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) The California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Frances Arnold (Pasadena, California);  Peter Meinhold (Pasadena, California);  Matthew W. Peters (Pasadena, California);  Rudi Fasan (Brea, California);  Mike M. Y. Chen (Pasadena, California)
ABSTRACT This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells.
FILED Friday, March 30, 2018
APPL NO 15/942001
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/32 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0042 (20130101)
C12N 9/0071 (20130101)
C12N 9/0077 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/04 (20130101) Original (OR) Class
C12P 7/06 (20130101)

Enzymes
C12Y 106/02004 (20130101)
C12Y 114/15 (20130101)
C12Y 114/14001 (20130101)
C12Y 114/15003 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/17 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648058 Phillips
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jonathan Phillips (Pacific Grove, California)
ABSTRACT A system and method of providing metal comprising objects via additive manufacturing techniques using an RES mixture. The RES process mixes a precursor compound and a chemical agent which thermally decomposes to form typically CO, H2, NHx, or some other reducing agent. Using the RES mixture, the additive manufacturing device reproduces an object from a sliced object model file layer-by-layer. Heat is applied to the patterned RES mixture to thermally decompose the chemical agent and reduce the precursor compound to a reduced metal species. This heating and reduction transforms the RES mixture from a general paste having little to no shear strength to an solid form exhibiting a much greater shear strength, allowing layer-by-layer generation of 3D object components.
FILED Thursday, March 22, 2018
APPL NO 15/928459
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/008 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/153 (20170801)
B29C 64/165 (20170801)
B29C 64/188 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 5/10 (20130101)
C22B 5/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648064 Atwater et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Millersville University of Pennsylvania (Millersville, Pennsylvania)
ASSIGNEE(S) Millersville University of Pennsylvania (Millersville, Pennsylvania);  The United States Of America As Represented By The Secretary Of The Army (Washington, District of Columbia)
INVENTOR(S) Mark Andrew Atwater (Sunbury, Pennsylvania);  Kris Allen Darling (Havre de Grace, Maryland);  Mark Allen Tschopp, Jr. (Bel Air, Maryland)
ABSTRACT A process for producing a metal foam includes mechanically working a metallic powder such that oxide particles are finely dispersed within a metallic matrix and annealing the mechanically worked metallic powder in a vacuum the annealed metallic powder such that intraparticle porosity is formed by decomposition of the oxide particles at elevated temperature to reduce the oxide particles to metallic form and liberate the oxygen atoms in gaseous form, thereby creating porosity.
FILED Tuesday, May 07, 2019
APPL NO 16/405265
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/1143 (20130101)
B22F 2009/043 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)

Alloys
C22C 1/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648065 Coyle et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Dennis Joseph Coyle (Clifton Park, New York);  Henry Charles McGuigan (Duanesburg, New York);  Krishnan Balaji Thattai Parthasarathy (Clifton Park, New York);  Matthew Hockemeyer (Albany, New York);  Daniel Gene Dunn (Guilderland, New York)
ABSTRACT Systems and methods for manufacturing unidirectional fiber prepreg tapes for CMC articles are provided. In one exemplary aspect, the method includes casting a matrix material on a carrier film to form a matrix film. The matrix material of the matrix film is then allowed to dry for a predetermined time. The matrix film is then wrapped on a drum and the matrix material is wet to a predetermined viscosity with a solvent. Thereafter, a fiber tow that includes of a plurality of fibers is wound about the drum so that the fiber tow penetrates into the matrix material and the matrix material impregnates the fiber tow to form the prepreg tape.
FILED Friday, December 01, 2017
APPL NO 15/829484
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/40 (20130101)
B28B 1/42 (20130101)
B28B 23/0006 (20130101)

Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics
B29B 15/12 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 37/0075 (20130101)
B29C 70/443 (20130101)
B29C 70/543 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 18/00 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/62868 (20130101)
C04B 35/62871 (20130101)
C04B 35/62894 (20130101)
C04B 2235/616 (20130101)
C04B 2235/5268 (20130101)
C04B 2235/6025 (20130101)
C04B 2235/6028 (20130101)
C04B 2237/38 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/10 (20130101)
C08J 5/24 (20130101)

Alloys
C22C 47/14 (20130101)
C22C 47/064 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648340 Darrow, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) David A. Darrow, Jr. (Stratford, Connecticut)
ABSTRACT A composite spar having an upper and lower wall region connected by leading and trailing edge regions is provided including a plurality of first laminates and a plurality of second laminates. The plurality of first laminates includes one or more intermediate modulus graphite plies having an intermediate modulus. The plurality of first laminates is arranged in one or more intermediate modulus layers to form at least a portion of the upper wall region, lower wall region, leading edge region and trailing edge region. The plurality of second laminates includes one or more high modulus graphite plies having a high modulus. The plurality of second laminates is arranged in one or more high modulus layers. The high modulus layers are generally interposed between intermediate modulus layers.
FILED Thursday, August 07, 2014
APPL NO 14/915162
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/20 (20130101)
B29C 70/30 (20130101)

Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 99/0025 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2105/106 (20130101)
B29K 2105/253 (20130101)
B29K 2307/04 (20130101)
B29K 2995/0082 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/082 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/147 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648361 Hagen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Gregory S. Hagen (Glastonbury, Connecticut)
ABSTRACT A debris monitoring system has a first sensor configured to generate a first signal indicating a presence of a metallic particle in a lubrication system. A second sensor is configured to generate a second signal indicating the presence of a metallic particle in the lubrication system. A signal processor is configured to determine a presence of a metallic particle in a fluid passage based on a comparison of at least the first signal and the second signal; the second signal being used to verify accuracy of the first signal. A gas turbine engine and a method for monitoring a fluid passage for debris are also disclosed.
FILED Tuesday, July 26, 2016
APPL NO 15/219335
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 21/003 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 7/06 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/35 (20130101)
F05D 2260/98 (20130101)

Lubricating
F16N 29/04 (20130101)
F16N 2250/32 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 15/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/2858 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648491 Limb et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Scott J. H. Limb (Palo Alto, California);  Gregory L. Whiting (Menlo Park, California)
ABSTRACT A stress-engineered frangible structure includes multiple discrete glass members interconnected by inter-structure bonds to form a complex structural shape. Each glass member includes strengthened (i.e., by way of stress-engineering) glass material portions that are configured to transmit propagating fracture forces throughout the glass member. Each inter-structure bond includes a bonding member (e.g., glass-frit or adhesive) connected to weaker (e.g., untreated, unstrengthened, etched, or thinner) glass member region(s) disposed on one or both interconnected glass members that function to reliably transfer propagating fracture forces from one glass member to other glass member. An optional trigger mechanism generates an initial fracture force in a first (most-upstream) glass member, and the resulting propagating fracture forces are transferred by way of inter-structure bonds to all downstream glass members. One-way crack propagation is achieved by providing a weaker member region only on the downstream side of each inter-structure bond.
FILED Tuesday, February 12, 2019
APPL NO 16/273397
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 17/00 (20130101)
B32B 17/10137 (20130101)

Manufacture, Shaping, or Supplementary Processes
C03B 23/20 (20130101)
C03B 23/203 (20130101)
C03B 27/00 (20130101)

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 15/00 (20130101)
C03C 21/00 (20130101)
C03C 21/001 (20130101)
C03C 21/002 (20130101)
C03C 27/06 (20130101)
C03C 27/10 (20130101)
C03C 27/044 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 1/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648583 Wiedemeier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brandon J. Wiedemeier (San Diego, California);  Tyler J. Harrison (San Diego, California);  Gregory W. Anderson (San Diego, California);  Carl E. Lostrom (San Diego, California)
ABSTRACT A pressure-compensated rupture disk assembly and method for subsea protection of a pressure vessel. The assembly and method incorporate a piston device, a dynamic piston seal configured to move the piston device when a predetermined pressure is reached; and a rupture disk adjacent the piston device, the rupture disk having a first pressure on a piston side and a second pressure on a second side, the rupture disk being configured to open when a predetermined pressure is exceeded.
FILED Friday, July 27, 2018
APPL NO 16/047067
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 17/162 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648619 Cornman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United States of America as Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jacob K. Cornman (Panama City, Florida);  Brian W. Toole (Panama City, Florida);  Kirk W. Vanzandt (Panama City, Florida)
ABSTRACT A pneumatic valve controller is provided for use with a refillable gas tank that has an inlet and an outlet with a spring-loaded valve disposed in the outlet. The spring-loaded valve is biased to define a flow path between an interior of the gas tank and the outlet. The controller's housing includes a cylinder with a gas filling port in fluid communication with a first axial end of the cylinder. The cylinder's second axial end is open and aligned with the spring-loaded valve. A piston is disposed in the cylinder. A check valve has an input and an output with the input in fluid communication with the gas filling port and the output in fluid communication with the inlet of the gas tank.
FILED Thursday, September 06, 2018
APPL NO 16/123050
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 15/063 (20130101)

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 5/06 (20130101) Original (OR) Class
F17C 5/007 (20130101)
F17C 13/04 (20130101)
F17C 2205/0335 (20130101)
F17C 2205/0388 (20130101)
F17C 2221/011 (20130101)
F17C 2227/04 (20130101)
F17C 2270/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648863 Ifarraguerri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Leidos, Inc. (Reston, Virginia)
ASSIGNEE(S) Leidos, Inc. (Reston, Virginia)
INVENTOR(S) Augie Ifarraguerri (Arlington, Virginia);  Brian Gorin (Setauket, New York);  J. Frank Camacho (Albuquerque, New Mexico);  Noah Christian (San Diego, California);  Robert Rice (Simi Valley, California)
ABSTRACT A system and process scans a target area at a distance of 3-30 m for one or more materials. Scanning is performed by a coherent transmit beam aimed with the help of a thermal camera. The active source of the beam is a supercontinuum (SC) laser. The transmitted source beam is modulated by a high-speed Fourier-transform spectrometer prior to interaction with the target. Target reflected source beam is detected by an infrared detector, along with a reference portion of the transmitted source beam, as a series of interferograms; passed through a digitizer for digitizing the interferograms; and processed to producing spectrograms, wherein the spectrograms are indicative of one or more materials on the target.
FILED Tuesday, May 15, 2018
APPL NO 15/979534
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/108 (20130101) Original (OR) Class
G01J 3/0275 (20130101)
G01J 3/4537 (20130101)
G01J 2003/423 (20130101)
G01J 2003/2813 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/359 (20130101)
G01N 2201/0612 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 2001/3528 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648882 Pickl et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)
INVENTOR(S) Carl Pickl (New Carlisle, Ohio);  James L. Rutledge (Fairborn, Ohio);  Marc D. Polanka (Huber Heights, Ohio);  Brian Crabtree (Beavercreek, Ohio);  Christopher Harkless (Vandalia, Ohio)
ABSTRACT A wake generator for placement in a wind tunnel between a wind source and a test object includes a first frame member having a first track formed thereon, where the first track has a shape including a first side that is substantially rounded and a second side that is substantially flat. The wake generator may include a mounting plate disposed within a perimeter of the first track, where the mounting plate is rotatable relative to the first frame member about a first axis. The wake generator may allow for better simulation of unsteady turbine wakes that influence cooling flow. The wake generator may also include a plurality of bars slidably engaged to the mounting plate and structurally configured to traverse along the first track when the mounting plate is rotated about the first axis.
FILED Wednesday, January 31, 2018
APPL NO 15/884865
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/08 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 9/04 (20130101)
G01M 9/065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648896 Ture et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation Applied Technology Directorate (AATD)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Cody Michael Ture (Fairport, New York);  Christopher M. Minnella (Pittsford, New York)
ABSTRACT An apparatus for assessment of a fluid system includes a scaffold housing with a plurality of internal cavities; a debris monitor module assembly to be selectively inserted into a first cavity of the plurality of internal cavities, the debris monitor module assembly to determine wear debris information in a lubricant; a lubricant condition monitor module assembly to be selectively inserted into a second cavity of the plurality of internal cavities, the lubricant condition monitor module assembly to determine lubricant condition information in the lubricant; and a processing module assembly that is configured to be selectively inserted into a third cavity of the plurality of internal cavities, the processing module assembly to provide communication to an external interface of at least one of the wear debris information and the lubricant condition information.
FILED Friday, September 11, 2015
APPL NO 15/525754
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0656 (20130101) Original (OR) Class
G01N 33/2858 (20130101)
G01N 33/2888 (20130101)
G01N 2015/1062 (20130101)
G01N 2015/1486 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648933 Clevenson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Hannah A. Clevenson (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT A light-trapping geometry enhances the sensitivity of strain, temperature, and/or electromagnetic field measurements using nitrogen vacancies in bulk diamond, which have exterior dimensions on the order of millimeters. In an example light-trapping geometry, a laser beam enters the bulk diamond, which may be at room temperature, through a facet or notch. The beam propagates along a path inside the bulk diamond that includes many total internal reflections off the diamond's surfaces. The NVs inside the bulk diamonds absorb the beam as it propagates. Photodetectors measure the transmitted beam or fluorescence emitted by the NVs. The resulting transmission or emission spectrum represents the NVs' quantum mechanical states, which in turn vary with temperature, magnetic field strength, electric field strength, strain/pressure, etc.
FILED Wednesday, December 26, 2018
APPL NO 16/232137
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/006 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/323 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648934 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Donggyu Kim (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Donggyu Kim (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT A method includes applying, to a sample exhibiting optical scattering and having a emission particles distributed therein that exhibit spin-dependent fluorescence, a magnetic field to shift a resonance frequency of each emission particle in a position-dependent manner. The method also includes exciting the sample with an excitation beam that causes at least one emission particle to emit spin-dependent fluorescence and detecting the emitted spin-dependent fluorescence. The method also includes estimating a position of the emission particle(s) within the sample based on the spin-dependent fluorescence, the resonance frequency, and the magnetic field. The method also includes estimating optical transmission information for the sample based on a wavefront of the excitation beam and the estimated position. The optical transmission information including a measure of an optical field at each position of an emission particle.
FILED Thursday, January 17, 2019
APPL NO 16/250524
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/006 (20130101) Original (OR) Class
G01N 24/10 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 60/20 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/323 (20130101)

Optical Elements, Systems, or Apparatus
G02B 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648955 DeGreeff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lauryn E. DeGreeff (Washington, District of Columbia);  Christopher J. Katilie (Washington, District of Columbia)
ABSTRACT A method of detecting an analyte by: providing a derivatizing agent that is reactive with the analyte; delivering the derivatizing agent into a chamber; delivering a sample of a gas suspected of containing the analyte into the chamber before or after delivering the derivatizing agent, while the chamber is maintained at a temperature that retains the derivatizing agent and any analyte and that allows reaction between the derivatizing agent and any analyte in the chamber to form a derivatized analyte; warming the chamber to cause evaporation of any derivatized analyte; and delivering the derivatized analyte in the chamber into a gas chromatograph column.
FILED Friday, February 23, 2018
APPL NO 15/903166
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/96 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/06 (20130101)
G01N 30/12 (20130101) Original (OR) Class
G01N 30/20 (20130101)
G01N 30/30 (20130101)
G01N 2030/025 (20130101)
G01N 2030/042 (20130101)
G01N 2030/067 (20130101)
G01N 2030/126 (20130101)
G01N 2030/201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648958 Strong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Veronica A. Strong (Portland, Oregon);  Maher F. El-Kady (Los Angeles, California);  Richard Barry Kaner (Pacific Palisades, California)
ABSTRACT An interconnected corrugated carbon-based network comprising a plurality of expanded and interconnected carbon layers is disclosed. In one embodiment, each of the expanded and interconnected carbon layers is made up of at least one corrugated carbon sheet that is one atom thick. In another embodiment, each of the expanded and interconnected carbon layers is made up of a plurality of corrugated carbon sheets that are each one atom thick. The interconnected corrugated carbon-based network is characterized by a high surface area with highly tunable electrical conductivity and electrochemical properties.
FILED Wednesday, February 08, 2017
APPL NO 15/427210
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/26 (20130101)
B32B 3/28 (20130101)
B32B 9/007 (20130101)
B32B 9/041 (20130101)
B32B 9/045 (20130101)
B32B 18/00 (20130101)
B32B 27/32 (20130101)
B32B 2307/75 (20130101)
B32B 2307/202 (20130101)
B32B 2307/732 (20130101)
B32B 2429/02 (20130101)
B32B 2457/00 (20130101)
B32B 2457/08 (20130101)
B32B 2457/10 (20130101)
B32B 2457/12 (20130101)
B32B 2457/20 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/23 (20170801)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 2237/72 (20130101)
C04B 2237/086 (20130101)
C04B 2237/363 (20130101)
C04B 2237/592 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/0037 (20130101) Original (OR) Class

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 5/02 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/245 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648959 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Chongwu Zhou (Los Angeles, California);  Ahmad Abbas (Los Angeles, California)
ABSTRACT The inventors experimentally demonstrated NO2 gas sensing performance of multilayer black phosphorous (BP) field effect transistors. The BP sensors were sensitive to NO2 concentration down to 5 ppb making them comparable in sensitivity to the best 2D material based sensors. Raman spectroscopy comparison revealed no apparent change in the spectra before and after exposure to NO2, which shows that thick BP flakes can maintain their relative stability after sensing. Moreover, the BP device sensing performance fitted well with the Langmuir Isotherm for molecules adsorbed on a surface, which confirms charge transfer as the dominant mechanism for sensing. The systematic increase in conductance with increasing NO2 concentrations suggests NO2 molecules withdraw electrons and dope BP flakes with holes. These results lay the ground work for BP to be applied to various sensing applications including chemical, gas, and bio-sensors.
FILED Friday, May 05, 2017
APPL NO 15/587914
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/004 (20130101)
B23K 2101/38 (20180801)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/122 (20130101)
G01N 27/4141 (20130101)
G01N 33/0037 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 50/245 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648977 Walston et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Aging (NIA)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Jeremy D. Walston (Baltimore, Maryland);  Peter M. Abadir (Woodstock, Maryland);  Alka Jain (Columbia, Maryland);  Neal Fedarko (Columbia, Maryland)
ABSTRACT The invention described herein provides methods for treating a disease or disorder associated with angiotensin receptor signaling in a patient exhibiting elevated levels of ATIR autoantibodies. The invention also provides methods of identifying a patient suffering from a disease or disorder associated with angiotensin receptor signaling that may benefit from treatment with an angiotensin receptor blocker. Patients with elevated levels of ATIR autoantibodies are identified as candidates that particularly benefit from treatment with an angiotensin receptor blocker.
FILED Friday, October 28, 2016
APPL NO 15/769617
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/41 (20130101)
A61K 31/513 (20130101)
A61K 31/4178 (20130101)
A61K 31/4184 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649016 Rivera
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) David F Rivera (Westerly, Rhode Island)
ABSTRACT A probe is provided for measuring permittivity of a dielectric material. The probe includes side electrodes and a pivotable center electrode with a bulbous tip to contact the material. A mounting harness supports the side electrodes and a feed connector with the center electrode soldered to the connector. The tip includes a contoured surface for measurement and rotation on the material. The bulbous tip can rest perpendicularly or in a pivoted position on the material without a loss of measurement accuracy. A saddle ensures that a measurement of the reflection coefficient is near the bulbous tip. In use, a voltage wave generated by a vector network analyzer is guided between the electrodes toward the tip and into the material. The material reflects this voltage wave back to the analyzer. The ratio of the reflected and forward voltages forms a reflection coefficient as a baseline for measuring permittivity.
FILED Tuesday, November 20, 2018
APPL NO 16/195897
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 27/267 (20130101)
G01R 27/2623 (20130101)
G01R 27/2676 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649051 Dolgin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Benjamin P. Dolgin (Alexandria, Virginia);  Thomas Lavedas (Dulles, Virginia);  Joseph J. Fraundorfer (Bethesda, Maryland)
ABSTRACT A system and method for detecting a nucleus of interest in a chemical using a nuclear quadrupole resonance transition. An excitation pulse is used to excite one or more nuclei of interest, if they present in a sample, to an excited state, the energy of which depends on the magnetic field in the sample. The magnetic field in the sample is modulated, after the end of the excitation pulse, while the nuclei of interest decay from the excited state, so that the radiation they emit is frequency modulated. The frequency modulation is detected in the emitted radiation. In some embodiments a DC magnetic field is applied to the sample, during the application of the excitation pulse, to tune the frequency of the transition being excited.
FILED Thursday, December 21, 2017
APPL NO 15/851620
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/084 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/441 (20130101) Original (OR) Class
G01R 33/445 (20130101)
G01R 33/446 (20130101)
G01R 33/4608 (20130101)
G01R 33/4616 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649075 Schuman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) SRC, Inc. (North Syracuse, New York)
ASSIGNEE(S) SRC, Inc. (North Syracuse, New York)
INVENTOR(S) Harvey K. Schuman (Fayetteville, New York);  Ping G. Li (Elmhurst, New York)
ABSTRACT The present invention is directed to a method for processing radar signals in a distributed array radar that includes a first airborne platform and at least one second airborne platform. Doppler filtered radar return samples are obtained and a weight value is calculated as a function of first clutter signals and second clutter signals. The weight value is employed in a weight vector that is computed, as well, from a steering vector that need not be matched to the target vector. The weight vector is applied to a signal vector corresponding to the Doppler filtered radar return samples. An open loop feedback is implemented and configured to create beam pattern nulls at angles corresponding to the plurality of first interference signals within each of the Doppler bins without substantially tracking a position or velocity of the first airborne platform or the at least one second airborne platform.
FILED Tuesday, September 26, 2017
APPL NO 15/715492
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/288 (20130101)
G01S 7/414 (20130101)
G01S 13/003 (20130101)
G01S 13/87 (20130101)
G01S 13/5244 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649080 Ranney et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kenneth Irving Ranney (Rockville, Maryland);  Gregory James Mazzaro (Charleston, South Carolina);  Kyle Alexander Gallagher (Derwood, Maryland);  Stephen Freeman (Ellicott City, Maryland)
ABSTRACT A radar assembly for receiving signals at spaced frequencies from an unknown transmitting source comprising a receiver operative to receive signals; the receiver comprising a series of channels, each channel comprising a low pass filter configured to allow passage of a signal from an unknown transmitting source, an analog to digital converter configured to transform the signal from the unknown transmitting source to a digital signal, a Hilbert transform configured to transform the digital signal from the unknown transmitting source into a single sideband signal, a Fourier transform configured to transform the single sideband signal into a plurality of regularly spaced frequency samples, and an inverse Fourier transform for extracting regularly spaced frequency samples; whereby extracted pulses form a train of pulses that are inputted into an imager which utilizes synthetic aperture radar to form an image of the area of interest containing the unknown transmitting device and method thereof.
FILED Tuesday, August 08, 2017
APPL NO 15/671579
ART UNIT 2865 — Printing/Measuring and Testing
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 1/30 (20130101)
G01S 13/003 (20130101)
G01S 13/583 (20130101)
G01S 13/784 (20130101)
G01S 13/9011 (20130101) Original (OR) Class
G01S 13/9017 (20130101)
G01S 13/9058 (20190501)
G01S 19/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649117 Lewellen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico);  Government of the United States of America as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S)
INVENTOR(S) John Lewellen (Los Alamos, New Mexico);  John Harris (Albuquerque, New Mexico)
ABSTRACT A “multicube” retroreflector may include “nested” corner cubes. Such a design combines the ease of fabrication of conventional corner cubes (e.g., stamping from a sheet) and the ability to easily and densely package them with a greater range of angles over which light will be reflected back towards the source. Such multicube retroreflectors may reflect 50% more light than corner cube retroreflectors. A retroreflector, or an array of retroreflectors, may be used as part of a communication system. A modulated retroreflector or an array thereof can form the basis of a unique communication system. For instance, by using a modulated retroreflector, or an array of such retroreflectors, a host system (e.g., an aircraft) can receive data from a remote system (e.g., a drone, an air-dropped sensor package, etc.) in a way that is difficult to intercept, and minimizes the power, computation, and antenna pointing requirements for the remote system.
FILED Tuesday, November 21, 2017
APPL NO 15/818809
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/122 (20130101) Original (OR) Class
G02B 26/0816 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649142 Thapa et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rajesh Thapa (Manassas, Virginia);  Rafael R. Gattass (Washington, District of Columbia);  Daniel J. Gibson (Falls Church, Virginia);  Woohong Kim (Washington, District of Columbia);  L. Brandon Shaw (Woodbridge, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia)
ABSTRACT Systems and methods are disclosed for splicing crystal fibers to silica glass fibers. Embodiments of the present disclosure provide mechanically stable bonds with negligible optical transmission loss by splicing fibers through a thermally enhanced reaction bonding process at lower temperatures than the melting point of the crystal. In an embodiment, mixing of the materials at elevated temperatures forms a stable intermediary material which enhances strength and reduces the transmission losses.
FILED Friday, June 28, 2019
APPL NO 16/456262
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/02 (20130101)
G02B 6/2551 (20130101) Original (OR) Class
G02B 6/2553 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649161 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) NANOPRECISION PRODUCTS, INC. (El Segundo, California)
ASSIGNEE(S) CUDOQUANTA FLORIDA, INC. (Sarasota, Florida)
INVENTOR(S) Shuhe Li (Pasadena, California);  Robert Ryan Vallance (Newbury Park, California);  Michael K. Barnoski (Pacific Palisades, California)
ABSTRACT A hermetic optical fiber alignment assembly, including a first ferrule portion having a first surface provided with a plurality of grooves receiving the end sections of optical fibers, wherein the grooves define the location and orientation of the end sections with respect to the first ferrule portion, and a second ferrule portion having a second surface facing the first surface of the first ferrule, wherein the first ferrule portion is attached to the second ferrule portion with the first surface against the second surface, wherein a cavity is defined between the first ferrule portion and the second ferrule portion, wherein the cavity is wider than the grooves, and wherein a suspended section of each optical fiber is suspended in the cavity, and wherein the cavity is sealed with a sealant. The sealant extends around the suspended sections of the optical fibers within the cavity. An aperture is provided in at least one of the first ferrule portion and the second ferrule portion, exposing the cavity, wherein the sealant is feed through the aperture. In another aspect, the hermetic assembly provides optical alignment and a hermetic feedthrough for an opto-electronic module. In a further aspect, the hermetic assembly provides alignment and a terminal for access to an opto-electronic module.
FILED Tuesday, July 17, 2018
APPL NO 16/037705
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/3636 (20130101)
G02B 6/3838 (20130101)
G02B 6/3839 (20130101)
G02B 6/3861 (20130101)
G02B 6/3885 (20130101)
G02B 6/4214 (20130101)
G02B 6/4219 (20130101)
G02B 6/4248 (20130101) Original (OR) Class
G02B 6/4253 (20130101)
G02B 6/4292 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/4998 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649240 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Zhenqiang Ma (Middleton, Wisconsin);  Chang-Beom Eom (Madison, Wisconsin);  Jaeseong Lee (San Jose, California);  Daesu Lee (Madison, Wisconsin);  Sang June Cho (Fitchburg, Wisconsin);  Dong Liu (Madison, Wisconsin)
ABSTRACT Switches for electromagnetic radiation, including radiofrequency switches and optical switches, are provided. Also provided are methods of using the switches. The switches incorporate layers of high quality VO2 that are composed of a plurality of connected crystalline VO2 domains having the same crystal structure and orientation.
FILED Wednesday, January 02, 2019
APPL NO 16/237804
ART UNIT 2883 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0054 (20130101) Original (OR) Class
G02F 1/0147 (20130101)
G02F 1/313 (20130101)
G02F 2202/105 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649306 Skirlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Scott A. Skirlo (Boston, Massachusetts);  Cheryl Marie Sorace-Agaskar (Bedford, Massachusetts);  Marin Soljacic (Belmont, Massachusetts);  Simon Verghese (Arlington, Massachusetts);  Jeffrey S. Herd (Rowley, Massachusetts);  Paul William Juodawlkis (Arlington, Massachusetts);  Yi Yang (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts);  Mihika Prabhu (Cambridge, Massachusetts)
ABSTRACT An integrated optical beam steering device includes a planar dielectric lens that collimates beams from different inputs in different directions within the lens plane. It also includes an output coupler, such as a grating or photonic crystal, that guides the collimated beams in different directions out of the lens plane. A switch matrix controls which input port is illuminated and hence the in-plane propagation direction of the collimated beam. And a tunable light source changes the wavelength to control the angle at which the collimated beam leaves the plane of the substrate. The device is very efficient, in part because the input port (and thus in-plane propagation direction) can be changed by actuating only log2 N of the N switches in the switch matrix. It can also be much simpler, smaller, and cheaper because it needs fewer control lines than a conventional optical phased array with the same resolution.
FILED Monday, February 25, 2019
APPL NO 16/284161
ART UNIT 2883 — Optics
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4813 (20130101)
G01S 7/4814 (20130101)
G01S 7/4817 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/2955 (20130101)
G02F 1/3136 (20130101) Original (OR) Class
G02F 2001/311 (20130101)
G02F 2201/02 (20130101)
G02F 2201/06 (20130101)
G02F 2201/302 (20130101)
G02F 2203/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649970 Saxe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) INVINCEA, INC. (Fairfax, Virginia)
ASSIGNEE(S) Invincea, Inc. (Reston, Virginia)
INVENTOR(S) Joshua Daniel Saxe (Washington, District of Columbia);  David Peter Mentis (Fairfax, Virginia);  Anthony Chungku Wong (Arlington, Virginia)
ABSTRACT In some embodiments, a method includes receiving a plurality of descriptors via a network. Each descriptor includes at least one of a descriptor component or a keyword. The method further includes storing the plurality of descriptors in a database, and generating a database index of the plurality of descriptors based on at least one of the descriptor component or the keyword for each descriptor of the plurality of descriptors. The method further includes storing the database index in the database. The method further includes receiving a file component extracted from a file and identifying, based on the file component, a set of descriptors from the plurality of descriptors. The method further includes inferring, based on the set of descriptors, a measure of likelihood of a functionality associated with the file, and transmitting an indication of the measure to a user.
FILED Friday, March 14, 2014
APPL NO 14/212659
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/2272 (20190101) Original (OR) Class
G06F 16/24558 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650012 Wroblewski
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ronald J. Wroblewski (San Diego, California)
ABSTRACT A method involves receiving, from a user, a user query for data contained within a multi-dimensional dataset comprising a plurality of data objects, generating a multi-dimensional search box for use in searching the multi-dimensional dataset according to the user query, wherein the size of the multi-dimensional search box is approximated based upon a percentage of the scale of the dataset and upon the standard deviation of the data object distribution of the dataset, searching the multi-dimensional dataset using the multi-dimensional search box, and returning, to the user, data from the multi-dimensional dataset contained within the multi-dimensional search box. The multi-dimensional search box may be generated in part by modeling the range of values as an arbitrary start point within the multi-dimensional data set with extents that are Gaussian distributed with a standard deviation less than the scale of the data set.
FILED Thursday, December 15, 2016
APPL NO 15/379998
ART UNIT 2153 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/22 (20190101)
G06F 16/248 (20190101) Original (OR) Class
G06F 16/283 (20190101)
G06F 16/2462 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650110 Van Vaerenbergh et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Thomas Van Vaerenbergh (Palo Alto, California);  Jason Pelc (Palo Alto, California)
ABSTRACT A photonic circuit design system includes a photonic circuit design tool to facilitate user inputs to generate a photonic circuit netlist comprising a photonic design component of a photonic circuit design. The system includes a memory system to store the photonic circuit netlist and a component library comprising a plurality of predetermined photonic design components from which the photonic design component is selected. The component library further includes physical data associated with physical characteristics of the plurality of predetermined photonic design components. The system further includes a photonic circuit generator to access the photonic circuit netlist from the memory and the associated photonic design component from the component library based on the photonic circuit netlist and to implement hierarchical algorithm associated with a physical layout and an optical interconnection of the photonic design component in a photonic circuit package based on the physical characteristics to generate the photonic circuit design.
FILED Wednesday, July 08, 2015
APPL NO 15/741761
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/43 (20130101)
G02B 6/122 (20130101)

Electric Digital Data Processing
G06F 17/505 (20130101) Original (OR) Class
G06F 17/5045 (20130101)
G06F 17/5068 (20130101)
G06F 17/5072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650301 Alvarez-Icaza Rivera et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Rodrigo Alvarez-Icaza Rivera (Mountain View, California);  Rathinakumar Appuswamy (San Jose, California);  John V. Arthur (Mountain View, California);  Andrew S. Cassidy (San Jose, California);  Bryan L. Jackson (Fremont, California);  Paul A. Merolla (Palo Alto, California);  Dharmendra S. Modha (San Jose, California);  Jun Sawada (Austin, Texas)
ABSTRACT Embodiments of the invention provide a neurosynaptic system comprising a delay unit for receiving and buffering axonal inputs, and a neural computation unit for generating neuronal outputs by performing a set of computations based on at least one axonal input received by the delay unit. The system further comprises a permutation unit for receiving external inputs to the system, and transmitting external outputs from the system. The permutation unit maps each external input received as either an axonal input to the delay unit or an external output from the system. The permutation unit maps each neuronal output generated by the neural computation unit as either an axonal input to the delay unit or an external output from the system. The neural computation unit comprises multiple electronic neurons, multiple electronic axons, and a plurality of electronic synapse devices interconnecting the neurons with the axons.
FILED Thursday, May 08, 2014
APPL NO 14/273487
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101) Original (OR) Class
G06N 3/049 (20130101)
G06N 3/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650309 Andreopoulos et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Alexander Andreopoulos (San Jose, California);  Steven K. Esser (San Jose, California);  Jeffrey A. Kusnitz (Campbell, California)
ABSTRACT High dynamic range, high class count, high input rate winner-take-all on neuromorphic hardware is provided. In some embodiments, a plurality of thermometer codes are received by a neurosynaptic core. The plurality of thermometer codes are split into a plurality of intervals. One of the plurality of intervals is selected. A local maximum is determined within the one of the plurality of intervals. A global maximum is determined based on the local maximum.
FILED Tuesday, August 09, 2016
APPL NO 15/232370
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/049 (20130101)
G06N 3/063 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650499 Fleizach
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gregory K. Fleizach (San Diego, California)
ABSTRACT A memory device receives an original input image having at least one horizontal reticle or at least one vertical reticle. The memory device also receives a horizontal reticle mask image for horizontal reticles and/or a vertical reticle mask image for vertical reticles. A processor inpaints three regions: (1) vertical reticles with a horizontal filter, (2) horizontal reticles with a vertical filter, and (3) an intersection of the horizontal and vertical reticles with a two dimensional filter. A single inpainted image is produced. The processor determines whether a maximum change in any one of the first inpainted region, the second inpainted region or the third inpainted region equals or exceeds a predetermined threshold, and if so, repeating the inpainting steps. Once the maximum change in pixel intensity is less than the predetermined threshold the processing stops.
FILED Thursday, July 26, 2018
APPL NO 16/046705
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/005 (20130101) Original (OR) Class
G06T 5/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650515 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Satish Viswanath (Pepper Pike, Ohio);  Jacob Antunes (Cincinnati, Ohio);  Pallavi Tiwari (Shaker Heights, Ohio)
ABSTRACT Embodiments access an image of a region of interest (ROI) demonstrating cancerous pathology; extract radiomic features from the ROI; define a radiomic feature expression scene based on the ROI and radiomic features; generate a cluster map by superpixel clustering the expression scene; generate an expression map by repartitioning the cluster map into expression levels; compute a textural and spatial phenotypes for the expression map based on the expression levels; construct a radiomic spatial textural (RADISTAT) descriptor by concatenating the textural and spatial phenotypes; provide the RADISTAT descriptor to a machine learning classifier; receive, from the machine learning classifier, a first probability that the ROI is a responder or non-responder, or a second probability that the ROI will experience long-term survival or short-term survival, based, at least in part, on the RADISTAT descriptor; and generate a classification of the ROI as a responder or non-responder, or long-term survivor or short-term survivor.
FILED Wednesday, May 23, 2018
APPL NO 15/987137
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/52 (20130101)
G01N 2800/54 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5601 (20130101)
G01R 33/5602 (20130101)
G01R 33/5608 (20130101)
G01R 33/56341 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/1611 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/3241 (20130101)
G06K 9/6218 (20130101)
G06K 9/6267 (20130101)
G06K 2209/05 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10072 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650981 Surendranath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yogesh Surendranath (Cambridge, Massachusetts);  Stefan M. Kilyanek (Fayetteville, Arkansas);  Sterling B. Chu (Cambridge, Massachusetts)
ABSTRACT Disclosed herein is an electrode material comprising a carbon-containing substrate, comprising a surface and a plurality of RF moieties wherein each RF moiety is covalently bound to the surface; and each RF moiety comprises a fluorine atom. Also, disclosed herein is a method of preparing an electrode material.
FILED Monday, February 01, 2016
APPL NO 15/012089
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 11/12 (20130101)
C25B 11/14 (20130101)
C25B 11/0405 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/042 (20130101) Original (OR) Class
H01G 11/26 (20130101)
H01G 11/38 (20130101)
H01G 11/50 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/049 (20130101)
H01M 4/96 (20130101)
H01M 4/587 (20130101)
H01M 4/9083 (20130101)
H01M 8/20 (20130101)
H01M 8/188 (20130101)
H01M 10/054 (20130101)
H01M 10/0525 (20130101)
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)
Y02E 60/528 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651112 Malouin, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute Of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Bernard A. Malouin, Jr. (Westford, Massachusetts);  James Paul Smith (Chelmsford, Massachusetts);  Eric A. Browne (Westford, Massachusetts)
ABSTRACT The present invention generally relates to a microjet array for use as a thermal management system for a heat generating device, such as an RF device. The microjet array is formed in a jet plate, which is attached directly to the substrate containing the heat generating device. Additional enhancing features are used to further improve the heat transfer coefficient above that inherently achieved by the array. Some of these enhancements may also have other functions, such as adding mechanical structure, electrical connectivity or pathways for waveguides. This technology enables higher duty cycles, higher power levels, increased component lifetime, and/or improved SWaP for RF devices operating in airborne, naval (surface and undersea), ground, and space environments. This technology serves as a replacement for existing RF device thermal management solutions, such as high-SWaP finned heat sinks and cold plates.
FILED Monday, October 30, 2017
APPL NO 15/797784
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 1/0246 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/12 (20130101)
F28F 13/06 (20130101)
F28F 2260/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4871 (20130101)
H01L 23/4735 (20130101) Original (OR) Class

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20254 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651361 Brink et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Markus Brink (White Plains, New York);  Antonio D. Corcoles-Gonzalez (Mount Kisco, New York);  Jay M. Gambetta (Yorktown Heights, New York);  Sami Rosenblatt (White Plains, New York);  Firat Solgun (Ossining, New York)
ABSTRACT A technique relates a structure. An inductive element is on a first surface. A capacitive element is on the first surface and a second surface. An interconnect structure is between the first surface and the second surface.
FILED Wednesday, January 16, 2019
APPL NO 16/248981
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/481 (20130101)
H01L 24/13 (20130101)
H01L 27/18 (20130101)
H01L 39/025 (20130101) Original (OR) Class
H01L 39/223 (20130101)
H01L 39/2493 (20130101)
H01L 2224/13101 (20130101)
H01L 2224/13101 (20130101)
H01L 2224/73207 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/014 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 5/028 (20130101)
H01P 7/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651409 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Jinsong Huang (Lincoln, Nebraska);  Fawen Guo (Lincoln, Nebraska);  Liang Shen (Lincoln, Nebraska)
ABSTRACT A photodetector includes an anode that is transparent or partially transparent to light, a cathode and an active layer disposed between the anode and the cathode. The active layer includes a nanocomposite material that has a polymer blended with nanoparticles or organic electron trapping particles. The photodetector has a low dark current when not illuminated by light and has a high conductivity when illuminated by light, in which the light passes the anode and is absorbed by the active layer. The active layer has a thickness selected such that the photodetector has a narrowband spectral response.
FILED Tuesday, November 29, 2016
APPL NO 15/364064
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0036 (20130101)
H01L 51/0042 (20130101)
H01L 51/0072 (20130101)
H01L 51/0094 (20130101)
H01L 51/426 (20130101)
H01L 51/4273 (20130101) Original (OR) Class
H01L 2031/0344 (20130101)
H01L 2251/301 (20130101)
H01L 2251/303 (20130101)
H01L 2251/308 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651478 Pietron et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jeremy J Pietron (Washington, District of Columbia);  Michael B. Pomfret (Washington, District of Columbia);  Christopher N. Chervin (Washington, District of Columbia);  Debra R Rolison (Arlington, Virginia);  Jeffrey W Long (Alexandria, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jeremy J Pietron (Washington, District of Columbia);  Michael B. Pomfret (Washington, District of Columbia);  Christopher N. Chervin (Washington, District of Columbia);  Debra R Rolison (Arlington, Virginia);  Jeffrey W Long (Alexandria, Virginia)
ABSTRACT An article having a titanium, titanium carbide, titanium nitride, tantalum, aluminum, silicon, or stainless steel substrate, a RuO2 coating on a portion of the substrate; and a plurality of platinum nanoparticles on the RuO2 coating. The RuO2 coating contains nanoparticles of RuO2. A method of: immersing the substrate in a solution of RuO4 and a nonpolar solvent at a temperature that is below the temperature at which RuO4 decomposes to RuO2 in the nonpolar solvent in the presence of the article; warming the article and solution to ambient temperature under ambient conditions to cause the formation of a RuO2 coating on a portion of the article; and electrodepositing platinum nanoparticles on the RuO2 coating.
FILED Friday, December 21, 2012
APPL NO 13/723878
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/1216 (20130101)
C23C 18/1225 (20130101)
C23C 18/1295 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 5/34 (20130101)
C25D 15/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/92 (20130101)
H01M 4/925 (20130101)
H01M 4/8853 (20130101) Original (OR) Class
H01M 8/08 (20130101)
H01M 8/0236 (20130101)
H01M 8/1011 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/523 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651687 Chandrakasan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Anantha P. Chandrakasan (Belmont, Massachusetts);  Nachiket V. Desai (Cambridge, Massachusetts);  Chiraag Juvekar (Cambridge, Massachusetts);  Shubham Chandak (Menlo Park, California)
ABSTRACT A method and apparatus for achieving detuning for a resonant wireless power transfer system including cryptography is described. Detuning for a resonant wireless power transfer system including cryptography allows for detuning a wireless receiver based upon authentication between the wireless receiver and a wireless charger.
FILED Thursday, February 08, 2018
APPL NO 15/892158
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201) Original (OR) Class
H02J 50/80 (20160201)
H02J 50/90 (20160201)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/006 (20130101)
H04L 9/0662 (20130101)
H04L 9/3271 (20130101)
H04L 2209/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652013 Kwiat et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Duke University (Durham, North Carolina)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Duke University (Durham, North Carolina)
INVENTOR(S) Paul G. Kwiat (Savoy, Illinois);  Daniel J. Gauthier (Columbus, Ohio)
ABSTRACT A system, and methods, for transmitting quantum states between a first node and a second node, or among more than two nodes. Each node is characterized by an instantaneous spatial position, and the instantaneous spatial position of the second node is repositionable within a frame of reference associated with the first node. A hovering drone is adapted either for running a quantum key transmission protocol in secure communication with the first node, and/or for running a quantum key reception protocol in secure communication with the second node. Either drone may serve as a relay of optical data between a base station and another drone. Secure communication among more than two nodes may be reconfigured.
FILED Monday, May 20, 2019
APPL NO 16/416455
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Transmission
H04B 10/70 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0822 (20130101) Original (OR) Class
H04L 9/0852 (20130101)
H04L 9/0869 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652225 Koved et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lawrence Koved (Pleasantville, New York);  Bo Zhang (Hoboken, New Jersey)
ABSTRACT Using a stochastic queuing model to determine adjustments to be made to authentication system operation. In light of operational parameter values and the stochastic queuing model, a determination is made that adjusting the value of a particular parameter for handling authentication requests is likely to improve some aspect of system performance, and the request handling parameter is adjusted accordingly.
FILED Wednesday, June 24, 2015
APPL NO 14/748266
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/32 (20130101)
H04L 63/08 (20130101) Original (OR) Class
H04L 63/20 (20130101)
H04L 63/105 (20130101)

Wireless Communication Networks
H04W 12/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652353 Dinan et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) James Dinan (Hudson, Massachusetts);  Venkata Krishnan (Ashland, Massachusetts);  Srinivas Sridharan (Bangalore, India);  David A. Webb (Groton, Massachusetts)
ABSTRACT Technologies for communication with direct data placement include a number of computing nodes in communication over a network. Each computing node includes a many-core processor having an integrated host fabric interface (HFI) that maintains an association table (AT). In response to receiving a message from a remote device, the HFI determines whether the AT includes an entry associating one or more parameters of the message to a destination processor core. If so, the HFI causes a data transfer agent (DTA) of the destination core to receive the message data. The DTA may place the message data in a private cache of the destination core. Message parameters may include a destination process identifier or other network address and a virtual memory address range. The HFI may automatically update the AT based on communication operations generated by software executed by the processor cores. Other embodiments are described and claimed.
FILED Thursday, September 24, 2015
APPL NO 14/864369
ART UNIT 2449 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 15/17337 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/2852 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652666 Mayo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Nathanael K Mayo (Bristol, Rhode Island);  John B Blottman (North Andover, Massachusetts)
ABSTRACT A thermoacoustic device is provided with a housing having at least one open face. An active element is supported within the housing, and at least two electrodes are provided in electrical contact with the active element. A membrane is provided to cover each open face of the housing. The housing and membrane assembly is filled with a liquid. A signal lead is joined to the electrodes within the housing to communicate with the exterior of the housing. The active element can be made from a carbon nanotube sheet, and a gas can be provided in contact with the active element.
FILED Friday, September 21, 2018
APPL NO 16/137668
ART UNIT 2653 — Videophones and Telephonic Communications
CURRENT CPC
Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/06 (20130101)
H04R 1/025 (20130101)
H04R 23/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10653022 McDowell
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Navy Engineering Logistics Office (NELO)
APPLICANT(S) CACI, INC. - FEDERAL (Arlington, Virginia)
ASSIGNEE(S) CACI, Inc.-Federal (Arlington, Virginia)
INVENTOR(S) David McDowell (Arlington, Virginia)
ABSTRACT The housing relates to apparatus, systems, and methods for robust, adaptable, and deployable computing devices and radio systems. An embodiment can be the housing for a C-sUAS that can be deployed to detect, identify, locate and defeat hostile sUASs and locate the sUAS operators and that can be ruggedized and efficiently deployed for use in various power- and space-constrained mobile platforms and at fixed locations. An embodiment can be housing for a C-sUAS that operates under severe environmental conditions.
FILED Wednesday, July 10, 2019
APPL NO 16/508225
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/02 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/04 (20130101)
H05K 5/06 (20130101)
H05K 5/023 (20130101)
H05K 5/0204 (20130101)
H05K 5/0213 (20130101) Original (OR) Class
H05K 5/0247 (20130101)
H05K 7/20145 (20130101)
H05K 7/20336 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10653035 Chainer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Timothy Joseph Chainer (Putnam Valley, New York);  Pritish Ranjan Parida (Stamford, Connecticut);  Fanghao Yang (Somerset, New Jersey)
ABSTRACT Techniques that facilitate two-phase liquid cooling of an electronic device are provided. In one example, an apparatus, such as a cold plate device, comprises a first stackable layer and a second stackable layer. The first stackable layer comprises a first channel formed within the first stackable layer. The first channel comprises a first channel width and the first channel receives a coolant fluid via an inlet port of the apparatus. The second stackable layer comprises a second channel that provides a path for the coolant fluid to flow between the first channel and an outlet port of the apparatus. A width of the second channel increases along a flow direction of the coolant fluid that flows between the inlet port and the outlet port.
FILED Thursday, March 29, 2018
APPL NO 15/939797
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/12 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4882 (20130101)
H01L 23/473 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20254 (20130101) Original (OR) Class
H05K 7/20272 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE47983 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Thursday, June 28, 2018
APPL NO 16/022679
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10645886 Kremer et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) James Kremer (Lansing, Michigan);  James M. Tiedje (Lansing, Michigan);  Sheng-Yang He (Okemos, Michigan)
ABSTRACT The disclosure relates to a plant growth apparatus and related system to grow and maintain plants under controlled biotic conditions, for example to grow axenic (microbe-free) plants, gnotobiotic (defined microbiota) plants, and holoxenic (complex, or undefined microbiota) plants. This system allows aseptic bottom irrigation with water, soluble nutrients, chemicals, and/or microbiota. Plants can be inverted for dipping and/or vacuum infiltration. The system also allows for passive (gravity) drainage, thereby allowing for gas exchange and preventing root anoxia. A variety of plant growth substrates can be used within the plant growth apparatus as a plant growth medium. The plant growth apparatus, containing the growth substrate medium, can be completely flushed via the drainage port to remove potential toxic byproducts of the sterilization processes. The entire system is suitably constructed using autoclavable material.
FILED Friday, January 27, 2017
APPL NO 15/417522
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 7/00 (20130101)
A01G 9/00 (20130101)
A01G 9/02 (20130101)
A01G 22/00 (20180201) Original (OR) Class
A01G 24/00 (20180201)
A01G 31/02 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 60/216 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10645934 Newman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Lee Newman (Camillus, New York);  Daniel van der Lelie (Chapel Hill, North Carolina);  Safiyh Taghavi (Chapel Hill, North Carolina)
ASSIGNEE(S) BROOKHAVEN SCIENCE ASSOCIATES/BROOKHAVEN NATIONAL LABORATORY (Upton, New York)
INVENTOR(S) Lee Newman (Camillus, New York);  Daniel van der Lelie (Chapel Hill, North Carolina);  Safiyh Taghavi (Chapel Hill, North Carolina)
ABSTRACT The present invention relates to a novel species of Enterobacter, Enterobacter sp. 638, and to its use in connection, for example, with a method for increasing growth in a plant, increasing biomass in a plant, increasing fruit and/or seed productivity in a plant, increasing disease tolerance and/or resistance in a plant, and increasing drought tolerance and/or resistance in a plant, as compared to a control or wild-type plant grown under identical conditions without application of the inventive method or composition. The methods include applying an effective amount of a composition, which includes an isolated culture of Enterobacter sp. 638, to the plant.
FILED Thursday, March 10, 2011
APPL NO 13/634135
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 31/02 (20130101)
A01N 31/04 (20130101)
A01N 35/02 (20130101)
A01N 37/40 (20130101)
A01N 43/38 (20130101)
A01N 63/00 (20130101) Original (OR) Class
A01N 63/00 (20130101)
A01N 63/02 (20130101)
A01N 63/04 (20130101)
A01N 63/10 (20200101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 1/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646502 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) Lawrence Livermore National Security (Livermore, California)
INVENTOR(S) Sally J. DeNardo (El Macero, California);  Gerald L. DeNardo (El Macero, California);  Rodney L. Balhorn (Livermore, California)
ABSTRACT This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
FILED Wednesday, September 13, 2017
APPL NO 15/703848
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101) Original (OR) Class
A61K 47/55 (20170801)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/545 (20170801)
A61K 47/645 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646505 Schulz et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Michael D. Schulz (South Pasadena, California);  Carl M. Blumenfeld (Weston, Florida);  Robert H. Grubbs (South Pasadena, California);  Julia R. Greer (San Marino, California);  Daryl Wei Liang Yee (Pasadena, California)
ABSTRACT This disclosure is directed to structured compositions, including DNA-functionalized scaffolds, for drug capture, and methods and devices for sequestering chemotherapeutics from physiological fluids using the functionalized scaffolds.
FILED Wednesday, September 06, 2017
APPL NO 15/696474
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101) Original (OR) Class
A61K 47/58 (20170801)
A61K 47/549 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101)
A61L 29/085 (20130101)
A61L 31/08 (20130101)
A61L 31/10 (20130101)
A61L 31/14 (20130101)
A61L 31/16 (20130101)
A61L 2300/258 (20130101)
A61L 2400/12 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/10 (20130101)
C08F 293/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646598 Conti et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Peter S. Conti (Pasadena, California);  Hancheng Cai (Alhambra, California);  Zibo Li (Logan, Utah);  Shuanglong Liu (Alhambra, California)
ABSTRACT Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula where A is a functional group selected from group consisting of an amine, a carboxylic acid, an ester, a carbonyl, a thiol, an azide and an alkene, and B is a functional group selected from the group consisting of hydrogen, an amine, a carboxylic acid, and ester, a carbonyl, a thiol, an azide and an alkene. Also disclosed are conjugate of the BFC and a targeting moiety, which may be a peptide or antibody. Also disclosed are metal complexes of the BFC/targeting moiety conjugates that are useful as radiopharmaceuticals, imaging agents or contrast agents.
FILED Monday, June 27, 2016
APPL NO 15/194425
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/082 (20130101)
A61K 51/088 (20130101)
A61K 51/0474 (20130101) Original (OR) Class
A61K 51/0482 (20130101)
A61K 51/1093 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 487/08 (20130101)

Peptides
C07K 5/1021 (20130101)
C07K 7/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646821 Glatzmaier
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Gregory C. Glatzmaier (Golden, Colorado)
ABSTRACT Techniques for hydrogen sensing and mitigation are provided. As one example, a device includes a chamber and a membrane that is permeable to a first gas and is impermeable to a second gas. The membrane separates the chamber from a gas mixture that contains the first gas, such that the first gas in the gas mixture can only enter the chamber via the membrane. The device also includes a pressure sensor configured to measure a pressure within the chamber.
FILED Thursday, October 12, 2017
APPL NO 15/782198
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/228 (20130101) Original (OR) Class
B01D 53/326 (20130101)
B01D 69/12 (20130101)
B01D 71/022 (20130101)
B01D 2256/16 (20130101)
B01D 2257/102 (20130101)
B01D 2257/7027 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/0606 (20130101)
H01M 8/0687 (20130101)
H01M 8/04089 (20130101)
H01M 8/04365 (20130101)
H01M 8/04425 (20130101)
H01M 8/04798 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646846 Jung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yung Joon Jung (Lexington, Massachusetts);  Hyun Young Jung (Malden, Massachusetts);  Swastik Kar (Belmont, Massachusetts);  Chi Won Ahn (Deajeon, South Korea);  Mildred Dresselhaus (Arlington, Massachusetts);  Paulo Antonio Trindade Araujo (Belo Horizonte-MG, Brazil)
ABSTRACT Inter-allotropic transformations of carbon are provided using moderate conditions including alternating voltage pulses and modest temperature elevation. By controlling the pulse magnitude, small-diameter single-walled carbon nanotubes are transformed into larger-diameter single-walled carbon nanotubes, multi-walled carbon nanotubes of different morphologies, and multi-layered graphene nanoribbons.
FILED Monday, September 14, 2015
APPL NO 15/510789
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/087 (20130101) Original (OR) Class
B01J 2219/0803 (20130101)
B01J 2219/0879 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/16 (20170801)
C01B 32/18 (20170801)
C01B 32/168 (20170801)
C01B 32/184 (20170801)
C01B 2202/08 (20130101)
C01B 2204/04 (20130101)
C01B 2204/06 (20130101)
C01B 2204/22 (20130101)
C01B 2204/24 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/734 (20130101)
Y10S 977/842 (20130101)
Y10S 977/932 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646921 Yang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Peidong Yang (Kensington, California);  Nigel H. Becknell (Albany, California);  Yoonkook Son (Emeryville, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peidong Yang (Kensington, California);  Nigel H. Becknell (Albany, California);  Yoonkook Son (Emeryville, California)
ABSTRACT Described herein are metallic excavated nanoframes and methods for producing metallic excavated nanoframes. A method may include providing a solution including a plurality of excavated nanoparticles dispersed in a solvent, and exposing the solution to chemical corrosion to convert the plurality of excavated nanoparticles into a plurality of excavated nanoframes.
FILED Monday, March 26, 2018
APPL NO 15/935331
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/892 (20130101)
B01J 35/002 (20130101)
B01J 35/026 (20130101)
B01J 35/0033 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0018 (20130101) Original (OR) Class
B22F 1/0085 (20130101)
B22F 1/0088 (20130101)
B22F 7/008 (20130101)
B22F 2001/0029 (20130101)
B22F 2001/0037 (20130101)
B22F 2301/10 (20130101)
B22F 2301/15 (20130101)
B22F 2301/25 (20130101)
B22F 2301/35 (20130101)
B22F 2303/40 (20130101)
B22F 2998/10 (20130101)

Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof
B82B 3/008 (20130101)
B82B 3/0038 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 11/0494 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646960 Rubenchik et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Alexander M. Rubenchik (Livermore, California);  Manyalibo Joseph Matthews (Livermore, California);  Johannes Trapp (Dresden, Germany)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Alexander M. Rubenchik (Livermore, California);  Manyalibo Joseph Matthews (Livermore, California);  Johannes Trapp (Dresden, Germany)
ABSTRACT The present disclosure relates to a powdered bed fusion additive manufacturing (PBFAM) apparatus. The apparatus uses a container for holding a quantity of powdered material. The container has a bottom wall for supporting the powdered material, wherein the bottom wall is made from the same material as the powdered material. A temperature sensing subsystem is coupled to a portion of the container for detecting a temperature of the container. A laser generates an optical beam directed at the powdered material held by the container for melting the powdered material. A controller receives temperature information from the temperature sensing subsystem and determines an absorptivity of the powdered material based on the temperature information.
FILED Tuesday, October 03, 2017
APPL NO 15/723922
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/0006 (20130101)
B23K 26/034 (20130101)
B23K 26/083 (20130101)
B23K 26/342 (20151001) Original (OR) Class
B23K 26/0626 (20130101)
B23K 26/0869 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/153 (20170801)
B29C 64/255 (20170801)
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646964 Stagon et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  University of North Florida Board of Trustees (Jacksonville, Florida)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  University of North Florida Board of Trustees (Jacksonville, Florida)
INVENTOR(S) Stephen Peter Stagon (Jacksonville, Florida);  Hanchen Huang (Boston, Massachusetts);  Paul Robert Elliott (Boston, Massachusetts)
ABSTRACT Bonded surfaces are formed by adhering first nanorods and second nanorods to respective first and second surfaces. The first shell is formed on the first nanorods and the second shell is formed on the second nanorods, wherein at least one of the first nanorods and second nanorods, and the first shell and the second shell are formed of distinct metals. The surfaces are then exposed to at least one condition that causes the distinct metals to form an alloy, such as eutectic alloy having a melting point below the temperature at which the alloy is formed, thereby bonding the surfaces upon which solidification of the alloy.
FILED Tuesday, July 19, 2016
APPL NO 15/746536
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 35/02 (20130101)
B23K 35/26 (20130101)
B23K 35/0227 (20130101)
B23K 35/0261 (20130101)
B23K 35/264 (20130101) Original (OR) Class
B23K 2101/40 (20180801)
B23K 2101/42 (20180801)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 24/27 (20130101)
H01L 24/29 (20130101)
H01L 24/32 (20130101)
H01L 24/83 (20130101)
H01L 2224/293 (20130101)
H01L 2224/293 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/2745 (20130101)
H01L 2224/2782 (20130101)
H01L 2224/2919 (20130101)
H01L 2224/2929 (20130101)
H01L 2224/3201 (20130101)
H01L 2224/3201 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/04026 (20130101)
H01L 2224/05082 (20130101)
H01L 2224/05124 (20130101)
H01L 2224/05124 (20130101)
H01L 2224/05144 (20130101)
H01L 2224/05144 (20130101)
H01L 2224/05155 (20130101)
H01L 2224/05155 (20130101)
H01L 2224/05164 (20130101)
H01L 2224/05164 (20130101)
H01L 2224/05166 (20130101)
H01L 2224/05166 (20130101)
H01L 2224/05171 (20130101)
H01L 2224/05171 (20130101)
H01L 2224/05178 (20130101)
H01L 2224/05178 (20130101)
H01L 2224/05181 (20130101)
H01L 2224/05181 (20130101)
H01L 2224/05184 (20130101)
H01L 2224/05184 (20130101)
H01L 2224/05186 (20130101)
H01L 2224/05186 (20130101)
H01L 2224/05186 (20130101)
H01L 2224/05186 (20130101)
H01L 2224/05583 (20130101)
H01L 2224/05618 (20130101)
H01L 2224/05618 (20130101)
H01L 2224/05624 (20130101)
H01L 2224/05624 (20130101)
H01L 2224/05639 (20130101)
H01L 2224/05639 (20130101)
H01L 2224/05647 (20130101)
H01L 2224/05647 (20130101)
H01L 2224/05655 (20130101)
H01L 2224/05655 (20130101)
H01L 2224/05664 (20130101)
H01L 2224/05664 (20130101)
H01L 2224/05669 (20130101)
H01L 2224/05669 (20130101)
H01L 2224/8385 (20130101)
H01L 2224/27418 (20130101)
H01L 2224/27444 (20130101)
H01L 2224/27444 (20130101)
H01L 2224/27452 (20130101)
H01L 2224/29005 (20130101)
H01L 2224/29005 (20130101)
H01L 2224/29109 (20130101)
H01L 2224/29111 (20130101)
H01L 2224/29116 (20130101)
H01L 2224/29124 (20130101)
H01L 2224/29139 (20130101)
H01L 2224/29144 (20130101)
H01L 2224/29147 (20130101)
H01L 2224/29205 (20130101)
H01L 2224/29209 (20130101)
H01L 2224/29211 (20130101)
H01L 2224/29213 (20130101)
H01L 2224/29299 (20130101)
H01L 2224/29299 (20130101)
H01L 2224/29309 (20130101)
H01L 2224/29311 (20130101)
H01L 2224/29313 (20130101)
H01L 2224/29313 (20130101)
H01L 2224/29316 (20130101)
H01L 2224/29318 (20130101)
H01L 2224/29318 (20130101)
H01L 2224/29324 (20130101)
H01L 2224/29324 (20130101)
H01L 2224/29339 (20130101)
H01L 2224/29339 (20130101)
H01L 2224/29344 (20130101)
H01L 2224/29344 (20130101)
H01L 2224/29347 (20130101)
H01L 2224/29347 (20130101)
H01L 2224/32012 (20130101)
H01L 2224/32501 (20130101)
H01L 2224/32506 (20130101)
H01L 2224/83099 (20130101)
H01L 2224/83193 (20130101)
H01L 2224/83203 (20130101)
H01L 2224/83203 (20130101)
H01L 2224/83805 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/0102 (20130101)
H01L 2924/01014 (20130101)
H01L 2924/01014 (20130101)
H01L 2924/01322 (20130101)
H01L 2924/05341 (20130101)
H01L 2924/05432 (20130101)
H01L 2924/05442 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646969 Ranjan
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut)
ASSIGNEE(S) HAMILTON SUNSTRAND CORPORATION (Windsor Locks, Connecticut)
INVENTOR(S) Ram Ranjan (West Hartford, Connecticut)
ABSTRACT A heat exchanger includes a first additively manufactured layer including axial fins extending in a first direction and transverse fins extending in a second direction transverse to the first direction, the first layer defining a flow path in the first direction. The heat exchanger also includes a second additively manufactured layer including axial fins extending in the second and transverse fins extending in the first direction, the second layer defining a second flow path in the second direction.
FILED Wednesday, December 02, 2015
APPL NO 14/956439
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/26 (20130101) Original (OR) Class

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 9/0037 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/02 (20130101)
F28F 13/18 (20130101)
F28F 21/04 (20130101)
F28F 2250/106 (20130101)
F28F 2255/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647037 Rodriguez et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
INVENTOR(S) Jennifer N. Rodriguez (Lathrop, California);  Duncan J. Maitland (College Station, Texas);  Thomas S. Wilson (San Leandro, California)
ABSTRACT Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
FILED Tuesday, August 09, 2016
APPL NO 15/232619
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/5663 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2075/00 (20130101)
B29K 2105/046 (20130101)
B29K 2995/0093 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/18 (20130101)
B32B 5/32 (20130101)
B32B 2266/08 (20130101)
B32B 2266/0278 (20130101)
B32B 2535/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/3228 (20130101)
C08G 18/3278 (20130101)
C08G 18/3284 (20130101)
C08G 2101/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/38 (20130101)
C08J 2205/052 (20130101)
C08J 2207/10 (20130101)
C08J 2375/04 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647061 Kelly et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Brett Kelly (Berkeley, California);  Robert Panas (Dublin, California);  Maxim Shusteff (Oakland, California);  Christopher Spadaccini (Oakland, California);  Hayden Taylor (Berkeley, California);  Indrasen Bhattacharya (Berkeley, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Brett Kelly (Berkeley, California);  Robert Panas (Dublin, California);  Maxim Shusteff (Oakland, California);  Christopher Spadaccini (Oakland, California);  Hayden Taylor (Berkeley, California);  Indrasen Bhattacharya (Berkeley, California)
ABSTRACT A method of forming a three dimensional (3D) object is disclosed. The method may involve providing a volume of photo-curable resin contained within an optically transparent resin container, and simultaneously directing optical projections from an optical subsystem at a plurality of angles θ through the volume of photo-curable resin. The optical beams are directed about a z axis extending through the volume of photo-curable resin. Each of the projections is provided with a calculated 2D spatial intensity function which creates a 3D intensity map. The projections act over a fixed temporal exposure period, during which the net exposure dose is sufficient to cure select portions of the volume of photo-curable resin, and to leave other portions uncured, to form a desired 3D part.
FILED Friday, May 12, 2017
APPL NO 15/593947
ART UNIT 1749 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801)
B29C 64/232 (20170801)
B29C 64/241 (20170801)
B29C 64/245 (20170801)
B29C 64/264 (20170801)
B29C 64/277 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647064 Farmer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Joseph C. Farmer (Tracy, California);  Alexander M. Rubenchik (Livermore, California);  Raymond J. Beach (Livermore, California);  Robert J. Deri (Pleasanton, California);  Edward I. Moses (Livermore, California);  Bassem S. El-Dasher (Livermore, California);  Sarath K. Menon (Monterey, California);  Terry McNelley (Monterey, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Joseph C. Farmer (Tracy, California);  Alexander M. Rubenchik (Livermore, California);  Raymond J. Beach (Livermore, California);  Robert J. Deri (Pleasanton, California);  Edward I. Moses (Livermore, California);  Bassem S. El-Dasher (Livermore, California);  Sarath K. Menon (Monterey, California);  Terry McNelley (Monterey, California)
ABSTRACT An apparatus for use in a friction stir operation, such as friction stir welding (FSW) or friction stir processing (FSP). The apparatus may have a rotating tool adapted to be plunged into a material, where the material is susceptible to being softened by heating. The rotating tool may further be adapted to be advanced along a surface of the material. An optical energy generating subsystem may be used to heat a portion of the material using optical energy as the tool is advanced along the material.
FILED Tuesday, October 16, 2012
APPL NO 14/360570
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/1245 (20130101)
B23K 31/02 (20130101)
B23K 2201/18 (20130101)
B23K 2203/10 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/06 (20130101)
B29C 65/72 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647580 Ye et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Jianchao Ye (Tracy, California);  Juergen Biener (San Leandro, California);  Patrick Campbell (Oakland, California);  Wen Chen (Livermore, California);  Julie A. Jackson (Livermore, California);  Bryan D. Moran (Pleasanton, California);  James Oakdale (Castro Valley, California);  William Smith (Oakland, California);  Christopher Spadaccini (Oakland, California);  Marcus A. Worsley (Hayward, California);  Xiaoyu Zheng (Blacksburg, Virginia)
ABSTRACT In one embodiment, a composition of matter includes: a plurality of ligaments each independently comprising one or more layers of graphene; where the plurality of ligaments are arranged according to a deterministic three-dimensional (3D) pattern. In another embodiment, a method of forming a deterministic three-dimensional (3D) architecture of graphene includes: forming or providing a substrate structurally characterized by a predefined 3D pattern; forming one or more layers of metal on surfaces of the substrate; and forming one or more layers of graphene on surfaces of the metal.
FILED Thursday, January 26, 2017
APPL NO 15/417134
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/182 (20170801) Original (OR) Class
C01B 32/184 (20170801)
C01B 32/186 (20170801)
C01B 2204/02 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/03 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/734 (20130101)
Y10S 977/842 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647622 Dagle et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Robert A. Dagle (Richland, Washington);  Vanessa M. Dagle (Richland, Washington)
ABSTRACT A simplified processes for producing desired chemicals such as butenes from feedstock mixtures containing ethanol. In one set of embodiments this is performed in a single step, wherein a feed containing ethanol in a gas phase is passed over an acidic metal oxide catalyst having a transition metal dispersion of at least 5% on a metal oxide support. The ethanol content of the feedstock mixture may vary from 10 to 100 percent of the feed and in those non-eat applications the ethanol feed may contain water.
FILED Thursday, May 31, 2018
APPL NO 15/994531
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/066 (20130101)
B01J 29/035 (20130101)
B01J 35/1019 (20130101)

Acyclic or Carbocyclic Compounds
C07C 1/20 (20130101) Original (OR) Class
C07C 11/08 (20130101)
C07C 2521/06 (20130101)
C07C 2529/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647625 Dagle et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Vanessa Dagle (Richland, Washington);  Robert A. Dagle (Richland, Washington)
ABSTRACT A process for producing 1,3-butadiene (BD) from ethanol in a single step by s7passing a mixture containing ethanol in a gas phase over a multifunctional catalyst having a transition metal dispersion of at least 30% on a silica metal oxide support. In some examples the multifunctional catalyst comprises a silica metal oxide having a surface area of at least 200 m{circumflex over ( )}2/g. The multifunctional catalyst can include a transition metal oxide, a silica metal oxide made from a high purity silica gel, mesoporous silica and fumed silica, such as high purity SBA16, SBA15, or Davisil grade 646.
FILED Monday, December 11, 2017
APPL NO 15/837382
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/20 (20130101)
C07C 1/20 (20130101)
C07C 1/24 (20130101) Original (OR) Class
C07C 11/167 (20130101)
C07C 2521/06 (20130101)
C07C 2521/08 (20130101)
C07C 2523/42 (20130101)
C07C 2523/46 (20130101)
C07C 2523/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647748 Kong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Leopold Kong (Bethesda, Maryland);  Ian A. Wilson (La Jolla, California);  Natalia De Val (San Diego, California);  Andrew B. Ward (San Diego, California);  Dennis Burton (La Jolla, California);  Linling He (San Diego, California);  Jiang Zhu (San Diego, California)
ABSTRACT The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
FILED Wednesday, October 31, 2018
APPL NO 16/176200
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 47/64 (20170801)
A61K 47/6929 (20170801)
A61K 2039/645 (20130101)
A61K 2039/5258 (20130101)
A61K 2039/6031 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647914 Zaitseva et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Natalia P. Zaitseva (Livermore, California);  M. Leslie Carman (San Ramon, California);  Andrew M. Glenn (Livermore, California);  Andrew Neil Mabe (Livermore, California);  Stephen A. Payne (Castro Valley, California)
ABSTRACT Scintillating plastics resistant to crazing and fogging, methods of making and using the same are disclosed. The scintillating plastics include: one or more primary polymers present in an amount ranging from about 40 wt % to about 95 wt %; one or more secondary polymers present in an amount ranging from about 1 wt % to about 60 wt %; and one or more fluors present in an amount ranging from about 0.1 wt % to about 50 wt %. Methods of making such plastics include: creating a homogenous mixture of precursor materials including primary polymer, secondary polymer, and fluor in the amounts set forth above; and polymerizing the homogenous mixture. Methods of using such plastics include: exposing the scintillating plastic to one or more extreme environmental conditions for a predetermined amount of time without generating crazing or fogging within the scintillating plastic. Various additional features and specific embodiments of these inventive concepts are also disclosed.
FILED Friday, March 17, 2017
APPL NO 15/462512
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 11/025 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 1/2033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647938 Lahouij et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland);  UCHICAGO ARGONNE, LLC (Chicago, Illinois);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) PIXELLIGENT TECHNOLOGIES, LLC (Baltimore, Maryland);  UCHICAGO ARGONNE, LLC (Chicago, Illinois);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Imene Lahouij (Philadelphia, Pennsylvania);  Robert Carpick (Philadelphia, Pennsylvania);  Andrew Jackson (Baltimore, Maryland);  Harman Khare (Philadelphia, Pennsylvania);  Nitya Gosvami (Philadelphia, Pennsylvania);  Nicholaos G. Demas (Chicago, Illinois);  Robert A. Erck (Chicago, Illinois);  Aaron C. Greco (Chicago, Illinois);  George R. Fenske (Chicago, Illinois);  Wei Xu (Baltimore, Maryland);  Gregory Cooper (Baltimore, Maryland);  Zhiyun Chen (Baltimore, Maryland)
ABSTRACT The presently disclosed technology relates to a nano-additives to improve the performance of lubricants, oils, and greases. More specifically, the presently disclosed technology relates to applying capped metal oxide nanoparticles, such as capped zirconia nanoparticles, in the lubricants to produce a tribofilms on the lubricating surfaces to provide wear protection to the said surfaces. Also, the interaction of the capped zirconia nanoparticles with other commonly used additives in lubricants may further optimize the performance of the resulting tribofilms.
FILED Wednesday, May 04, 2016
APPL NO 15/569271
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/10 (20130101) Original (OR) Class
C10M 141/10 (20130101)
C10M 171/06 (20130101)
C10M 2201/14 (20130101)
C10M 2203/1006 (20130101)
C10M 2205/00 (20130101)
C10M 2205/0285 (20130101)
C10M 2207/2805 (20130101)
C10M 2209/1033 (20130101)
C10M 2223/045 (20130101)
C10M 2229/025 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2210/04 (20130101)
C10N 2220/082 (20130101)
C10N 2220/084 (20130101)
C10N 2230/58 (20130101)
C10N 2240/02 (20130101)
C10N 2240/04 (20130101)
C10N 2240/10 (20130101)
C10N 2250/10 (20130101)
C10N 2250/121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648009 McBrayer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes, Inc. (Davis, California)
ASSIGNEE(S) Novoyzmes, Inc. (Davis, California)
INVENTOR(S) Brett McBrayer (Davis, California);  Tarana Shaghasi (Davis, California);  Elena Vlasenko (Davis, California)
ABSTRACT The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.
FILED Wednesday, August 29, 2018
APPL NO 16/115930
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/22 (20130101)
C12N 9/248 (20130101)
C12N 9/2402 (20130101)
C12N 9/2437 (20130101)
C12N 9/2445 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/12 (20130101)
C12P 19/14 (20130101) Original (OR) Class
C12P 21/02 (20130101)
C12P 2203/00 (20130101)

Enzymes
C12Y 302/01 (20130101)
C12Y 302/01004 (20130101)
C12Y 302/01008 (20130101)
C12Y 302/01021 (20130101)
C12Y 302/01037 (20130101)
C12Y 302/01091 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648063 Mudring et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Anja-Verena Mudring (Stockholm, Sweden);  Denis Prodius (Ames, Iowa);  Cajetan Ikenna Nlebedim (Ames, Iowa)
ABSTRACT A chemical dissolution method is provided for use in recycling rare earth metal-containing material such as permanent magnet material including end-of-life magnet shapes, magnet scrap and Terfenol-D alloy material by mixing the rare earth metal-containing material and an aqueous solution of a copper (II) salt to dissolve the material in the solution. The dissolved rare earth metal is then precipitated from the aqueous solution as a rare earth metal compound, such as a rare earth metal oxalate, sulfate or phosphate from which rare earth metal oxide can be obtained.
FILED Monday, June 25, 2018
APPL NO 15/998079
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Production and Refining of Metals; Pretreatment of Raw Materials
C22B 7/006 (20130101)
C22B 59/00 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 10/234 (20151101)
Y02P 10/236 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648091 Kuhl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Opus 12 Incorporated (Berkeley, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) Opus 12 Inc. (Berkeley, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Kendra P. Kuhl (Berkeley, California);  Etosha R. Cave (Berkeley, California);  George Leonard (Berkeley, California)
ABSTRACT A platform technology that uses a novel membrane electrode assembly including a cathode layer comprising a reduction catalyst and a first anion-and-cation-conducting polymer, an anode layer comprising an oxidation catalyst and a cation-conducting polymer, a membrane layer comprising a cation-conducting polymer, the membrane layer arranged between the cathode layer and the anode layer and conductively connecting the cathode layer and the anode layer, in a COx reduction reactor has been developed. The reactor can be used to synthesize a broad range of carbon-based compounds from carbon dioxide.
FILED Wednesday, May 03, 2017
APPL NO 15/586173
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/04 (20130101)
C25B 9/10 (20130101) Original (OR) Class
C25B 11/0405 (20130101)
C25B 11/0415 (20130101)
C25B 13/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648224 Briese et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) GED INTEGRATED SOLUTIONS, INC. (Twinsburg, Ohio)
ASSIGNEE(S) GED Integrated Solutions, Inc. (Twinsburg, Ohio)
INVENTOR(S) William A. Briese (Hinckley, Ohio);  John Grismer (Cuyahoga Falls, Ohio);  Timothy B. McGlinchy (Twinsburg, Ohio)
ABSTRACT An insulating glass unit (IGU) assembly line comprising a registration station capable of interleaving double and triple pane IGUs in accordance with an IOU production schedule. Visual indicators or prompts instruct operators at the assembly line in configuring a sequence of IGUs. Triple pane IGUs are assembled with minimal contamination of a center glass lite. A non-contact Bernoulli pad is used to lift a glass lite off from a horizontal or vertical support that conveys it from a glass washer to the registration station. Each of multiple pads has a capacity to lift approximately seven to ten pounds. Use of multiple pads per glass sheet or lite allows lites having dimensions up to 70 by 100 inches (assuming glass thickness of one quarter inch) to be assembled.
FILED Monday, November 28, 2016
APPL NO 15/361811
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 19/00 (20130101)

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 15/28 (20130101)
B65G 37/00 (20130101)
B65G 49/061 (20130101)
B65G 49/067 (20130101)
B65G 51/03 (20130101)

Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 3/673 (20130101)
E06B 3/67326 (20130101) Original (OR) Class
E06B 3/67365 (20130101)
E06B 3/67369 (20130101)
E06B 3/67382 (20130101)
E06B 2003/66395 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/53 (20150115)
Y10T 29/534 (20150115)
Y10T 29/49826 (20150115)
Y10T 29/49828 (20150115)
Y10T 29/49829 (20150115)
Y10T 29/49885 (20150115)
Y10T 29/49904 (20150115)
Y10T 29/53409 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648616 Garosshen et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNITED TECHNOLOGIES RESEARCH CENTER (East Hartford, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Thomas J. Garosshen (Glastonbury, Connecticut);  Ellen Y. Sun (South Windsor, Connecticut);  Paul F. Croteau (Columbia, Connecticut);  Andrzej Ernest Kuczek (Bristol, Connecticut);  Tahany Ibrahim El-Wardany (Bloomfield, Connecticut);  Wenping Zhao (Glastonbury, Connecticut);  Justin R. Hawkes (Marlborough, Connecticut);  John A. Sharon (Manchester, Connecticut);  John P. Wesson (West Hartford, Connecticut);  Daniel V. Viens (Mansfield Center, Connecticut)
ABSTRACT A pressure vessel assembly includes a plurality of lobes, each lobe having at least one vertically arranged interior wall, the lobes positioned in a side by side arrangement such that a first interior wall of a first lobe is positioned adjacent a second interior wall of a second lobe, the first interior wall having a first wall top and bottom side, the second interior wall having a second wall top and bottom side, the first wall top side joined to the second wall top side and the first wall bottom side joined to the second wall bottom side. Also included are first and second end wall surfaces of each of the plurality of lobes. Further included is a plurality of end caps, each of the end caps joined to the end wall surfaces of the lobes, each of the end caps joined to at least one adjacent end cap.
FILED Tuesday, October 07, 2014
APPL NO 15/517010
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 15/0006 (20130101)

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 1/14 (20130101) Original (OR) Class
F17C 1/16 (20130101)
F17C 2201/056 (20130101)
F17C 2201/0152 (20130101)
F17C 2203/0617 (20130101)
F17C 2203/0643 (20130101)
F17C 2203/0646 (20130101)
F17C 2203/0663 (20130101)
F17C 2209/221 (20130101)
F17C 2209/222 (20130101)
F17C 2209/225 (20130101)
F17C 2209/2181 (20130101)
F17C 2221/012 (20130101)
F17C 2221/031 (20130101)
F17C 2221/033 (20130101)
F17C 2221/035 (20130101)
F17C 2223/035 (20130101)
F17C 2223/0123 (20130101)
F17C 2260/018 (20130101)
F17C 2270/0168 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/321 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648697 Wagner et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Michael Wagner (Highlands Ranch, Colorado);  Zhiwen Ma (Golden, Colorado);  Janna Martinek (Lafayette, Colorado);  Ty Neises (Broomfield, Colorado);  Craig Turchi (Lakewood, Colorado)
ABSTRACT An aspect of the present disclosure is a receiver for receiving radiation from a heliostat array that includes at least one external panel configured to form an internal cavity and an open face. The open face is positioned substantially perpendicular to a longitudinal axis and forms an entrance to the internal cavity. The receiver also includes at least one internal panel positioned within the cavity and aligned substantially parallel to the longitudinal axis, and the at least one internal panel includes at least one channel configured to distribute a heat transfer medium.
FILED Monday, March 05, 2018
APPL NO 15/911723
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Producing or Use of Heat Not Otherwise Provided For
F24J 2/46 (20130101)

Solar Heat Collectors; Solar Heat Systems
F24S 10/70 (20180501)
F24S 10/72 (20180501) Original (OR) Class
F24S 20/20 (20180501)
F24S 80/00 (20180501)
F24S 2020/18 (20180501)
F24S 2080/05 (20180501)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/41 (20130101)
Y02E 10/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648743 Kozubal et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Eric Kozubal (Superior, Colorado);  Jason David Woods (Boulder, Colorado);  Eric Jason Bonnema (Littleton, Colorado);  Ramin Teimouri Faramarzi (Pacific Palisades, California)
ABSTRACT A system comprising a first plurality of microchannels, a second plurality of microchannels in thermal communication with the first plurality of microchannels such that the first plurality of microchannels and second plurality of microchannels form a heat exchanger, and a phase change composite in thermal communication with the heat exchanger and methods of operating are disclosed herein.
FILED Tuesday, May 29, 2018
APPL NO 15/991275
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 5/0021 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 25/005 (20130101)
F25B 39/02 (20130101)
F25B 2400/24 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/0025 (20130101)
F28D 7/0091 (20130101) Original (OR) Class
F28D 15/0266 (20130101)
F28D 20/021 (20130101)
F28D 20/023 (20130101)
F28D 2015/0225 (20130101)
F28D 2021/0066 (20130101)
F28D 2021/0068 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/022 (20130101)
F28F 2260/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648786 Mann et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) NANOHMICS, INC. (Austin, Texas)
ASSIGNEE(S) NANOHMICS, INC. (Austin, Texas)
INVENTOR(S) Chris W Mann (Austin, Texas);  Sebastian Liska (Austin, Texas);  Joshua C Ruedin (Austin, Texas)
ABSTRACT A magnetoelastic sensor is provided for analyzing strain induced by a force causing mechanical deformation of a region of a substrate. The sensor includes a substrate that has a non-deformable region and a mechanically deformable region, the mechanically deformable region coupled to the non-deformable region by a linking structure. The sensor also has a transformer having a magnetic flux guide. The flux guide includes a magnetoelastic section having a magnetoelastic subsection configured to be strainable by deformation of the mechanically deformable region. In transformer embodiments, one or more drive coil and/or pickup coil has a width greater than the minimal width of the linking structure. Sensor embodiments include numerous configurations. The sensor is useful in methods for analyzing strain and force.
FILED Wednesday, August 29, 2018
APPL NO 16/116864
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 7/24 (20130101) Original (OR) Class

Coin-freed or Like Apparatus
G07F 7/00 (20130101)
G07F 7/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649102 Elmer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) John W. Elmer (Danville, California);  Alan T. Teruya (Livermore, California)
ABSTRACT Apparatus and method for analyzing an electron beam including a circular sensor disk adapted to receive the electron beam, an inner semi-circular slit in the circular sensor disk; an outer semi-circular slit in the circular sensor disk wherein the outer semi-circular slit is spaced from the first semi-circular slit by a fixed distance; a system for sweeping the electron beam radially outward from the central axis to the inner semi-circular slit and outer second semi-circular slit; a sensor structure operatively connected to the circular sensor disk wherein the sensor structure receives the electron beam when it passes over the inner semi-circular slit and the outer semi-circular slit; and a device for measuring the electron beam that is intercepted by the inner semi-circular slit and the outer semi-circular slit.
FILED Thursday, September 06, 2018
APPL NO 16/123069
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/2985 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 37/244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649117 Lewellen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico);  Government of the United States of America as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S)
INVENTOR(S) John Lewellen (Los Alamos, New Mexico);  John Harris (Albuquerque, New Mexico)
ABSTRACT A “multicube” retroreflector may include “nested” corner cubes. Such a design combines the ease of fabrication of conventional corner cubes (e.g., stamping from a sheet) and the ability to easily and densely package them with a greater range of angles over which light will be reflected back towards the source. Such multicube retroreflectors may reflect 50% more light than corner cube retroreflectors. A retroreflector, or an array of retroreflectors, may be used as part of a communication system. A modulated retroreflector or an array thereof can form the basis of a unique communication system. For instance, by using a modulated retroreflector, or an array of such retroreflectors, a host system (e.g., an aircraft) can receive data from a remote system (e.g., a drone, an air-dropped sensor package, etc.) in a way that is difficult to intercept, and minimizes the power, computation, and antenna pointing requirements for the remote system.
FILED Tuesday, November 21, 2017
APPL NO 15/818809
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/122 (20130101) Original (OR) Class
G02B 26/0816 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649198 Miller et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Micah D. Miller (Richland, Washington);  James Preston McKinley (Richland, Washington)
ABSTRACT Sample handling, processing and analysis methods and apparatus are described. According to one aspect, a sample processing method includes providing a sample, providing a reference frame which comprises a plurality of markers arranged in a predefined pattern, wherein individual ones of the markers are uniquely identifiable from others of the markers, and associating the reference frame comprising the markers with the sample. The markers are amenable to human or machine reading and for computational manipulation in some examples.
FILED Friday, March 11, 2016
APPL NO 15/068447
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2813 (20130101)
G01N 2001/282 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/34 (20130101)
G02B 21/367 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649514 Huang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Wei Huang (Austin, Texas);  Yazhou Zu (Austin, Texas);  Indrani Paul (Austin, Texas)
ABSTRACT A method and apparatus for managing processing power determine a supply voltage to supply to a processing unit, such as a central processing unit (CPU) or graphics processing unit (GPU), based on temperature inversion based voltage, frequency, temperature (VFT) data. The temperature inversion based VFT data includes supply voltages and corresponding operating temperatures that cause the processing unit's transistors to operate in a temperature inversion region. In one example, the temperature inversion based VFT data includes lower supply voltages and corresponding higher temperatures in a temperature inversion region of a processing unit. The temperature inversion based VFT data is based on an operating frequency of the processing unit. The apparatus and method adjust a supply voltage to the processing unit based on the temperature inversion based VFT data.
FILED Friday, September 23, 2016
APPL NO 15/274697
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649663 James et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Conrad D. James (Albuquerque, New Mexico);  Tu-Thach Quach (Albuquerque, New Mexico);  Sapan Agarwal (Dublin, California);  James Bradley Aimone (Albuquerque, New Mexico)
ABSTRACT A method and system for accessing a memory for a data processing system. The method comprises sending a read request for a plurality of locations in the memory to read the plurality of locations in parallel based on an upper bound for reading the memory. The upper bound for a number of locations is based on a group of constraints for the memory. The method receives a summed value of a plurality of memory values in the plurality of locations in the memory.
FILED Monday, July 31, 2017
APPL NO 15/665075
ART UNIT 2139 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 3/061 (20130101) Original (OR) Class
G06F 3/0638 (20130101)
G06F 3/0679 (20130101)
G06F 9/52 (20130101)
G06F 12/1441 (20130101)
G06F 2212/1052 (20130101)

Coding; Decoding; Code Conversion in General
H03M 7/3062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650700 White et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livemore, California)
INVENTOR(S) Gregory K. White (Livermore, California);  William H. Dunlop (Livermore, California);  T R Koncher (Brentwood, California);  Steve Kreek (Livermore, California)
ABSTRACT An incident simulation system supports an incident exercise in a virtual environment. The incident simulation system accesses a simulation plan defining an incident within a theater of operation. The incident simulation system simulates the incident exercise by displaying, to a participant in the incident exercise, images representing what the participant would see within the theater of operation as the participant moves within the theater of operation. The incident simulation system further simulates the incident by generating incident data indicating effects of the incident at target locations and at target times as the participant moves within the theater of operation. The incident simulation system further simulates the incident by displaying to the participant images representing the user experience that a detector would provide based on the generated incident data.
FILED Thursday, January 08, 2015
APPL NO 14/592854
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/02 (20130101)
G09B 19/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651048 Henry et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael David Henry (Albuquerque, New Mexico);  Travis Ryan Young (Albuquerque, New Mexico);  Erica Ann Douglas (Albuquerque, New Mexico)
ABSTRACT A fabrication process employing the use of ScAlN as an etch mask is disclosed. The ScAlN etch mask is chemically nonvolatile in fluorine-based etch chemistries and has a low sputter yield, resulting in greater etch mask selectivity and reduced surface roughness for silicon and other semiconductor materials. The ScAlN etch mask has an etch mask selectivity of greater than 200,000:1 relative to silicon compared to an etch mask selectivity of less than 40,000:1 for a prior art AlN etch mask relative to silicon. Further, due to reduced sputtering of the ScAlN etch mask, and thus reduced micromasking, the ScAlN etch mask yielded a surface roughness of 0.6 μm compared to a surface roughness of 2.8 μm for an AlN etch mask.
FILED Monday, August 12, 2019
APPL NO 16/537953
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02271 (20130101)
H01L 21/32133 (20130101) Original (OR) Class
H01L 21/68778 (20130101)
H01L 23/53214 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651323 Gessert
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Timothy A. Gessert (Conifer, Colorado)
ABSTRACT Disclosed embodiments include CdS/CdTe PV devices (100) having a back contact (110,112) with oxygen gettering capacity. Also disclosed are back contact structures (110, 112) and methods of forming a back contact in a CdS/CdTe PV device (100). The described contacts and methods feature a contact having a contact interface layer (100) comprising a contact interface material, a p-type dopant and a gettering metal.
FILED Tuesday, August 21, 2018
APPL NO 16/106571
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/3429 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02562 (20130101)
H01L 31/1828 (20130101)
H01L 31/02963 (20130101)
H01L 31/03925 (20130101)
H01L 31/022425 (20130101)
H01L 31/022441 (20130101) Original (OR) Class
H01L 31/022466 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651449 Kotov et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Nicholas A. Kotov (Ann Arbor, Michigan);  Siu-On Tung (Ann Arbor, Michigan);  Szu-Shen Ho (Ann Arbor, Michigan);  Samantha Rahmani (Canton, Michigan)
ABSTRACT Ion conducting membranes based on aramid nanofibers (ANFs) can be prepared using layer-by-layer assembly, sol-gel processing, evaporation, spin coating, doctor blading, or other methods. Porosity is controlled through choice of additives and processing.
FILED Thursday, February 19, 2015
APPL NO 15/120301
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/145 (20130101)
H01M 2/162 (20130101)
H01M 2/1686 (20130101) Original (OR) Class
H01M 4/382 (20130101)
H01M 8/20 (20130101)
H01M 8/188 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101)
H01M 10/0585 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/528 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651461 Bell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents, The University of Texas System (Edinburg, Texas)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents, The University of Texas System (Edinburg, Texas)
INVENTOR(S) Nelson S. Bell (Albuquerque, New Mexico);  Nancy A. Missert (Tijeras, New Mexico);  Karen Lozano (McAllen, Texas);  Yatinkumar N. Rane (Edinburg, Texas)
ABSTRACT A novel lithium battery cathode, a lithium ion battery using the same and processes and preparation thereof are disclosed. The battery cathode is formed by force spinning. Fiber spinning allows for the formation of core-shell materials using material chemistries that would be incompatible with prior spinning techniques. A fiber spinning apparatus for forming a coated fiber and a method of forming a coated fiber are also disclosed.
FILED Tuesday, May 01, 2018
APPL NO 15/968159
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/13 (20130101)
H01M 4/131 (20130101)
H01M 4/139 (20130101)
H01M 4/366 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/1391 (20130101)
H01M 10/052 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651504 Cheng et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Wildcat Discovery Technologies, Inc. (San Diego, California)
ASSIGNEE(S) Wildcat Discovery Technologies, Inc. (San Diego, California)
INVENTOR(S) Gang Cheng (San Diego, California);  Deidre Strand (San Diego, California);  Ye Zhu (San Diego, California);  Marissa Caldwell (San Diego, California)
ABSTRACT Additives to electrolytes that enable the formation of comparatively more robust SEI films on silicon anodes. The SEI films in these embodiments are seen to be more robust in part because the batteries containing these materials have higher coulombic efficiency and longer cycle life than comparable batteries without such additives.
FILED Friday, April 13, 2018
APPL NO 15/953130
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 10/0569 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651521 Onnerud et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
ASSIGNEE(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
INVENTOR(S) Tord Per Jens Onnerud (Wilton, Connecticut);  Jay Jie Shi (Acton, Massachusetts);  Ricky Edward Bowersock (Augusta, Georgia);  Gary Eugene Gayman (Augusta, Georgia);  Jason Peter Street (Augusta, Georgia)
ABSTRACT Lithium ion batteries are provided that include materials that provide advantageous endothermic functionalities contributing to the safety and stability of the batteries. The endothermic materials may include a ceramic matrix incorporating an inorganic gas-generating endothermic material. If the temperature of the lithium ion battery rises above a predetermined level, the endothermic materials serve to provide one or more functions to prevent and/or minimize the potential for thermal runaway, e.g., thermal insulation (particularly at high temperatures); (ii) energy absorption; (iii) venting of gases produced, in whole or in part, from endothermic reaction(s) associated with the endothermic materials, (iv) raising total pressure within the battery structure; (v) removal of absorbed heat from the battery system via venting of gases produced during the endothermic reaction(s) associated with the endothermic materials, and/or (vi) dilution of toxic gases (if present) and their safe expulsion from the battery system.
FILED Thursday, May 21, 2015
APPL NO 15/312888
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Fire-fighting
A62C 3/16 (20130101)
A62C 99/0018 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 5/18 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/06 (20130101)
H01G 11/10 (20130101)
H01G 11/66 (20130101)
H01G 11/74 (20130101)
H01G 11/78 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/02 (20130101)
H01M 2/127 (20130101)
H01M 2/0267 (20130101)
H01M 2/1016 (20130101)
H01M 2/1094 (20130101)
H01M 2/1258 (20130101)
H01M 10/0525 (20130101)
H01M 10/0587 (20130101)
H01M 10/617 (20150401)
H01M 10/653 (20150401)
H01M 10/658 (20150401) Original (OR) Class
H01M 2200/20 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651645 Cui et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) ABB Inc. (Cary, North Carolina)
ASSIGNEE(S) ABB Inc. (Cary, North Carolina)
INVENTOR(S) Tao Cui (Raleigh, North Carolina);  Reynaldo Nuqui (Cary, North Carolina);  Dmitry Ishchenko (Cary, North Carolina);  Zhenyuan Wang (Morrisville, North Carolina)
ABSTRACT Systems and methods for fault detection and protection in electric power systems that evaluates electromagnetic transients caused by faults. A fault can be detected using sampled data from a first monitored point in the power system. Detection of fault transients and associated characteristics, including transient direction, can also be extracted through evaluation of sample data from other monitored points in the power system. A monitoring device can evaluate whether to trip a switching device in response to the detection of the fault and based on confirmation of an indication of detection of fault transients at the other monitored points of the power system. The determination of whether to trip or activate the switching device can also be based on other factors, including the timing of receipt of an indication of the detection of the fault transients and/or an evaluation of the characteristics of the detected transients.
FILED Monday, March 21, 2016
APPL NO 15/075845
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/08 (20130101)

Emergency Protective Circuit Arrangements
H02H 1/04 (20130101)
H02H 1/043 (20130101)
H02H 1/046 (20130101)
H02H 7/28 (20130101) Original (OR) Class
H02H 7/261 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651652 Lian et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jianming Lian (Richland, Washington);  Yannan Sun (Richland, Washington);  Laurentiu D. Marinovici (Richland, Washington);  Karanjit Kalsi (Pasco, Washington);  Jacob Hansen (Seattle, Washington)
ABSTRACT Systems, methods, and computer media for managing frequency response in a power grid are provided herein. Individual grid-connected electrical devices can be turned on and/or off by corresponding frequency-responsive load controllers when frequency deviations beyond a threshold are detected. Each controller selects, for the corresponding electrical device, a frequency threshold from available frequencies in a frequency range. If the selected frequency falls within a deadband frequency range, then the controller sets the frequency threshold to a frequency outside of the deadband (e.g., to a closest available frequency outside of the deadband). On a system-wide level, this approximates a uniform distribution of frequency thresholds over the entire frequency range, including the deadband, and achieves the proper power-to-frequency relationship for grid stability. A supervisory coordinator can determine the frequency range from which a frequency threshold is selected based on aggregated power information for devices and controllers throughout the grid.
FILED Friday, April 22, 2016
APPL NO 15/746258
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/00 (20130101)
H02J 3/12 (20130101)
H02J 3/14 (20130101) Original (OR) Class
H02J 3/24 (20130101)
H02J 3/46 (20130101)
H02J 7/00 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/3225 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 20/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651785 Keenihan et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) DOW GLOBAL TECHNOLOGIES LLC (Midland, Michigan)
ASSIGNEE(S) DOW GLOBAL TECHNOLOGIES LLC (Midland, Michigan)
INVENTOR(S) James R. Keenihan (Midland, Michigan);  Leonardo C. Lopez (Midland, Michigan);  Joseph A. Langmaid (Caro, Michigan);  Shane Washburn (Oakland, California);  Darius Eghbal (Oakland, California);  Vijay Karthik Koneru (Santa Clara, California);  Kelvin L. Leung (Mountain View, California)
ABSTRACT A photovoltaic assembly comprising; (a) at least two photovoltaic components that are adjacent to each other in a first direction, each photovoltaic component comprising (i) a partial recess in communication with the partial recess in an adjacent photovoltaic component and (ii) one or more connector receptors aligned in a second direction which is non-parallel to the first direction; (b) a connector located at feast partially in the partial recess of the photovoltaic component and at least partially in the partial recess of the adjacent photovoltaic component so that the connector connects the photovoltaic component to the adjacent photovoltaic component, the connector comprising: (i) a flexible housing having a first end and a second end; (ii) one or more connection ports at the first end; (iii) one or more connection ports at the second end; and (iv) one more flexible electrical conductors that extend from the one or more connection ports at the first end to the one or more connection ports at the second end; wherein the connector is flexible so that the first end and the second end are movable relative to each other in a plane, out of the plane, or both; wherein the one or more connection ports at the first end and the one or more connection ports at the second end form a connection with the one or more connector receptors of the photovoltaic component and the adjacent photovoltaic component so that the connector electrically connects the photovoltaic component to the adjacent photovoltaic component.
FILED Wednesday, June 04, 2014
APPL NO 14/898608
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/25 (20141201)
H02S 40/34 (20141201) Original (OR) Class
H02S 40/36 (20141201)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 10/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652072 Moradi et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Hussein Moradi (Idaho Falls, Idaho);  Behrouz Farhang (Salt Lake City, Utah)
ABSTRACT Circularly pulse-shaped waveforms for communication systems are disclosed herein, including a single carrier modulation in which pulse-shaping is performed using a circular convolution by the transmitter for various modulation schemes. A transmitter, related method, and corresponding receiver are also disclosed for demodulation of the single carrier circularly pulse-shaped signal and data extraction.
FILED Friday, May 12, 2017
APPL NO 15/593691
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0413 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/265 (20130101)
H04L 27/2614 (20130101)
H04L 27/2628 (20130101)
H04L 27/2636 (20130101)
H04L 27/3494 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10653044 Chainer et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Timothy J. Chainer (Putnam Valley, New York);  Pritish R. Parida (Fishkill, New York);  Mark D. Schultz (Ossining, New York)
ABSTRACT A method for controlling a cooling system based on a heat dissipation of an electronic module and an ambient air temperature includes determining a combination of individual controls on components of the cooling system that achieve a specific amount of cooling based on a cooling power relationship for the plurality of components, the heat dissipation of the electronic module and the ambient air temperature, and applying the individual controls to the plurality of components.
FILED Thursday, January 10, 2013
APPL NO 13/738980
ART UNIT 2118 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20836 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10646356 Deshpande et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Ashish Deshpande (Austin, Texas);  Priyanshu Agarwal (Austin, Texas)
ABSTRACT The present disclosure includes a finger exoskeleton including a plurality of joints and a plurality of sensors configured to measure rotation of at least some of the plurality of joints of the finger exoskeleton. The finger exoskeleton also includes a series elastic actuator comprising a spring element, the series elastic actuator configured to rotate at least one of the plurality of joints. The finger exoskeleton also includes a computing device configured to control operation of the series elastic actuator based on a torque of the at least one of the plurality of joints, the torque determined at least based on the spring element and rotation of the at least one of the plurality of joints. The present disclosure also includes associated methods and hand exoskeletons.
FILED Thursday, June 16, 2016
APPL NO 15/184547
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/586 (20130101) Original (OR) Class
A61F 2002/5007 (20130101)
A61F 2002/5093 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0288 (20130101)
A61H 2201/149 (20130101)
A61H 2201/0165 (20130101)
A61H 2201/165 (20130101)
A61H 2201/501 (20130101)
A61H 2201/1215 (20130101)
A61H 2201/1635 (20130101)
A61H 2201/1676 (20130101)
A61H 2201/5038 (20130101)
A61H 2201/5043 (20130101)
A61H 2201/5046 (20130101)
A61H 2201/5069 (20130101)
A61H 2205/067 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/152 (20130101)
A63B 21/4019 (20151001)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646452 Dave et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey);  Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Rajesh N. Dave (Princeton, New Jersey);  Ramani Susarla (Broad View Heights, Ohio);  Boris Khusid (New Providence, New Jersey);  Anagha A. Bhakay (Philadelphia, Pennsylvania);  Ecevit A. Bilgili (Woodbridge, New Jersey);  Fernando Muzzio (Pennington, New Jersey)
ABSTRACT The present disclosure provides improved stripfilm based pharmaceutical products (e.g., for enhancing dissolution and bioavailability). More particularly, the present disclosure provides improved systems/methods for fabricating stripfilm based pharmaceutical products by utilizing higher viscosity film forming precursors and drying methods that accomplish improved/faster drying and provide improved/excellent content uniformity of active pharmaceutical agents in the stripfilm based pharmaceutical products. Exemplary systems/methods advantageously use high viscosity, bio-compatible polymeric precursors, (optional use of surface modified drug powders), and convective drying for fabrication of thin films loaded with nano and/or micro sized particles of poorly water-soluble active pharmaceutical ingredients (APIs) to achieve improved active content uniformity and very fast dissolution from poorly water soluble actives, while accomplishing fast drying during the fabrication process. The present disclosure provides for the fast drying (e.g., via low temperature forced convection) of biocompatible polymer films loaded with poorly water-soluble drug nano-particles.
FILED Monday, March 17, 2014
APPL NO 14/777191
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00063 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/006 (20130101)
A61K 9/0056 (20130101)
A61K 9/7007 (20130101) Original (OR) Class
A61K 31/216 (20130101)
A61K 31/343 (20130101)
A61K 47/32 (20130101)
A61K 47/38 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/003 (20130101)
B29C 39/14 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2007/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646580 Murthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia);  Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia);  Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) Niren Murthy (Berkeley, California);  Eric Seth Gilbert (Decatur, Georgia);  Xinghai Ning (Athens, Georgia);  Mark Goodman (Atlanta, Georgia);  Bryan Stubblefield (Atlanta, Georgia)
ABSTRACT This disclosure relates to conjugates for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate under conditions such that the conjugate is transported across the bacterial cell wall. Typically, the conjugate comprises an oligosaccharide and a molecule of interest. In certain embodiments, the molecule of interest may be a tracer or an antibiotic.
FILED Thursday, November 02, 2017
APPL NO 15/801892
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 45/06 (20130101)
A61K 47/61 (20170801) Original (OR) Class
A61K 49/0021 (20130101)
A61K 49/0032 (20130101)
A61K 49/0054 (20130101)
A61K 51/06 (20130101)
A61K 51/065 (20130101)

Polysaccharides; Derivatives Thereof
C08B 31/00 (20130101)

Compositions of Macromolecular Compounds
C08L 3/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646846 Jung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yung Joon Jung (Lexington, Massachusetts);  Hyun Young Jung (Malden, Massachusetts);  Swastik Kar (Belmont, Massachusetts);  Chi Won Ahn (Deajeon, South Korea);  Mildred Dresselhaus (Arlington, Massachusetts);  Paulo Antonio Trindade Araujo (Belo Horizonte-MG, Brazil)
ABSTRACT Inter-allotropic transformations of carbon are provided using moderate conditions including alternating voltage pulses and modest temperature elevation. By controlling the pulse magnitude, small-diameter single-walled carbon nanotubes are transformed into larger-diameter single-walled carbon nanotubes, multi-walled carbon nanotubes of different morphologies, and multi-layered graphene nanoribbons.
FILED Monday, September 14, 2015
APPL NO 15/510789
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/087 (20130101) Original (OR) Class
B01J 2219/0803 (20130101)
B01J 2219/0879 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/16 (20170801)
C01B 32/18 (20170801)
C01B 32/168 (20170801)
C01B 32/184 (20170801)
C01B 2202/08 (20130101)
C01B 2204/04 (20130101)
C01B 2204/06 (20130101)
C01B 2204/22 (20130101)
C01B 2204/24 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/734 (20130101)
Y10S 977/842 (20130101)
Y10S 977/932 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10646896 Schwartz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Jeffrey Schwartz (Princeton, New Jersey);  Joshua Spechler (Cherry Hill, New Jersey);  Romain Fardel (New York, New York);  Kelly Lim (Princeton, New Jersey)
ABSTRACT A construct that supports cell attachment and alignment including a substrate that is incompatible with photolithography conditions, containing a physical pattern in at least part of one surface, the physical pattern optionally bearing a coating of a metal alkoxide, oxide or mixed oxide-alkoxide thereon and a Self-Assembled Monolayer of Phosphonate (SAMP) covalently attached thereto, which phosphonate contains functionality adapted for cell binding. The construct optionally also contains cells attached thereto. Also disclosed are methods of preparing such a construct.
FILED Thursday, July 13, 2017
APPL NO 15/649033
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/32 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2533/32 (20130101)
C12N 2535/10 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647671 Wuest
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) William M. Wuest (Wallingford, Pennsylvania)
ABSTRACT The present invention includes novel analogs of promysalin useful in preventing or treating a microbial infection. The present invention also includes methods preventing or treating a microbial infection in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention.
FILED Tuesday, April 18, 2017
APPL NO 16/091685
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/401 (20130101)
A61K 31/401 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Heterocyclic Compounds
C07D 207/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647733 Lin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Wenbin Lin (Chicago, Illinois);  Kuntal Manna (Chicago, Illinois);  Teng Zhang (Chicago, Illinois)
ABSTRACT Metal-organic framework (MOFs) compositions based on nitrogen donor-based organic bridging ligands, including ligands based on 1,3-diketimine (NacNac), bipyridines and salicylaldimine, were synthesized and then post-synthetically metalated with metal precursors, such as complexes of first row transition metals. Metal complexes of the organic bridging ligands could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.
FILED Monday, March 30, 2015
APPL NO 15/129853
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/18 (20130101)
B01J 31/1691 (20130101)
B01J 31/1815 (20130101)
B01J 2531/16 (20130101)
B01J 2531/48 (20130101)
B01J 2531/824 (20130101)
B01J 2531/827 (20130101)
B01J 2531/842 (20130101)
B01J 2531/845 (20130101)
B01J 2531/847 (20130101)

Acyclic or Carbocyclic Compounds
C07C 5/03 (20130101)
C07C 37/07 (20130101)
C07C 41/20 (20130101)
C07C 209/02 (20130101)

Heterocyclic Compounds
C07D 207/04 (20130101)
C07D 207/06 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/025 (20130101)
C07F 7/003 (20130101) Original (OR) Class
C07F 7/1876 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/544 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647810 Loy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Douglas A. Loy (Tucson, Arizona);  Peter McFadden (Tucson, Arizona);  Robb E. Bagge (Tucson, Arizona)
ABSTRACT Thermally reworkable epoxy resins prepared through a Diels-Alder reaction are described herein. A maleimide component is reacted with an electron donating component having a furan ring attached to an epoxy ether to produce the epoxy resins. The epoxy component generated by this method can be cured with different diamines lo form a robust network of epoxy material. The robust epoxy material is used as a reversible thermoset and as an adhesive. The robust epoxy network is heated at 90° C. temperature in a retro Diels-Alder fashion to produce colorless starting materials of the maleimide component and the furan component.
FILED Tuesday, August 09, 2016
APPL NO 15/751807
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 59/022 (20130101)
C08G 59/24 (20130101)
C08G 59/26 (20130101)
C08G 59/306 (20130101) Original (OR) Class
C08G 59/504 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 163/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647953 Schlenoff et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Joseph B. Schlenoff (Tallahassee, Florida);  Carlos Arias (Tallahassee, Florida)
ABSTRACT An article suitable for inducing quasispherical cell clustering is provided. The article comprising: a layer suitable for culturing quasispherical cell clusters, the layer comprising a bulk region comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte and at least one predominantly negatively charged positive polyelectrolyte, a back surface region, and a front surface region, wherein the front surface region comprises a net negative fixed surface charge density of between about 0.4 micromole per m2 and about 1.5 micromole per m2.
FILED Monday, January 25, 2016
APPL NO 15/005115
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/20 (20130101) Original (OR) Class
C12M 25/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647954 Kozbial
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) FLASKWORKS, LLC (Newton, Massachusetts)
ASSIGNEE(S) FLASKWORKS, LLC (Newton, Massachusetts)
INVENTOR(S) Andrew Kozbial (East Boston, Massachusetts)
ABSTRACT A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
FILED Thursday, November 15, 2018
APPL NO 16/192062
ART UNIT 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/20 (20130101)
C12M 23/22 (20130101)
C12M 23/34 (20130101) Original (OR) Class
C12M 23/38 (20130101)
C12M 25/14 (20130101)
C12M 29/10 (20130101)
C12M 41/00 (20130101)
C12M 41/48 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101)
C12N 2506/115 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648006 Arnold et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) The California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Frances Arnold (Pasadena, California);  Peter Meinhold (Pasadena, California);  Matthew W. Peters (Pasadena, California);  Rudi Fasan (Brea, California);  Mike M. Y. Chen (Pasadena, California)
ABSTRACT This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells.
FILED Friday, March 30, 2018
APPL NO 15/942001
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/32 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0042 (20130101)
C12N 9/0071 (20130101)
C12N 9/0077 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/04 (20130101) Original (OR) Class
C12P 7/06 (20130101)

Enzymes
C12Y 106/02004 (20130101)
C12Y 114/15 (20130101)
C12Y 114/14001 (20130101)
C12Y 114/15003 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/17 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648028 Ju et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Zengmin Li (Flushing, New York);  John Robert Edwards (St. Louis, Missouri);  Yasuhiro Itagaki (New York, New York)
ABSTRACT This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose.
FILED Monday, November 26, 2018
APPL NO 16/200549
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/11 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/14 (20130101)
C07H 21/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 1/6872 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6876 (20130101)
C12Q 2525/117 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2535/101 (20130101)
C12Q 2535/101 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/107 (20130101)
C12Q 2563/107 (20130101)
C12Q 2565/501 (20130101)
C12Q 2565/501 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648917 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
INVENTOR(S) Jian Yang (State College, Pennsylvania);  Jimin Peter Kim (State College, Pennsylvania);  Zhiwei Xie (State College, Pennsylvania)
ABSTRACT In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing includes disposing a fluorophore in a biological environment, wherein the fluorophore includes a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further includes exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, includes hydrogen ions, halide ions, and/or halogens.
FILED Wednesday, April 06, 2016
APPL NO 15/564561
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 57/00 (20130101)
C09B 69/109 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1018 (20130101)
C09K 2211/1466 (20130101)
C09K 2211/1483 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 21/77 (20130101) Original (OR) Class
G01N 21/6428 (20130101)
G01N 31/16 (20130101)
G01N 31/221 (20130101)
G01N 2021/6432 (20130101)
G01N 2021/7786 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/19 (20150115)
Y10T 436/145555 (20150115)
Y10T 436/173845 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648957 Khusid et al.
FUNDED BY
Department of the Interior (DOI)
Bureau of Reclamation (USBR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Industry-University Cooperative Research Centers (IUCRC)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey);  Government of the United States of America, as Represented by The U.S. Department of Interior, The Bureau of Reclamation (Denver, Colorado)
ASSIGNEE(S) Government of the United States of America, The Bureau of Reclamation (Denver, Colorado);  New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Boris Khusid (New Providence, New Jersey);  Katherine L. Guerra (Golden, Colorado);  Frank Leitz (Evergreen, Colorado);  Yueyang Shen (Ithaca, New York);  Ezinwa O. Elele (Newark, New Jersey);  Qian Lei (Newark, New Jersey)
ABSTRACT A benchtop device flow setup for determining the effectiveness of magnetic treatment of feed water for reducing mineral scaling includes two similar branches, both equipped with a reverse osmosis membrane and a pump that operate in the transient regime at the same flow rate and transmembrane pressure. The flow setup is further fed with a solution at the same level of supersaturation measured in a stirred reactor, however, only one branch exposes the feed to a magnetic field.
FILED Friday, December 22, 2017
APPL NO 15/851776
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Separation
B01D 61/10 (20130101)
B01D 61/025 (20130101)
B01D 2311/04 (20130101)
B01D 2311/04 (20130101)
B01D 2311/24 (20130101)
B01D 2311/243 (20130101)
B01D 2311/246 (20130101)
B01D 2311/2607 (20130101)
B01D 2311/2642 (20130101)
B01D 2311/2642 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/008 (20130101)
C02F 1/441 (20130101)
C02F 1/481 (20130101)
C02F 1/484 (20130101)
C02F 2209/001 (20130101)
C02F 2209/05 (20130101)
C02F 2209/11 (20130101)
C02F 2303/22 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0606 (20130101)
G01N 15/0612 (20130101)
G01N 15/0618 (20130101)
G01N 15/0625 (20130101)
G01N 15/0656 (20130101)
G01N 31/02 (20130101) Original (OR) Class
G01N 33/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649914 Caccamo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Marco Caccamo (Urbana, Illinois);  Rodolfo Pellizzoni (Waterloo, Canada);  Renato Mancuso (Urbana, Illinois);  Rohan Tabish (Urbana, Illinois);  Saud Wasly (Jeddah, Saudi Arabia)
ABSTRACT An embodiment may involve determining that a first logical partition of a scratchpad memory coupled to a processor core is empty and a first application is scheduled to execute; instructing a direct memory access (DMA) engine to load the first application into the first logical partition and then instructing the processor core to execute the first application from the first logical partition; while the first application is being executed from the first logical partition, determining that a second logical partition of the scratchpad memory is empty and a second application is scheduled to execute; instructing the DMA engine to load the second application into the second logical partition; determining that execution of the first application has completed; and instructing the DMA engine to unload the first application from the first logical partition and instructing the processor core to execute the second application from the second logical partition.
FILED Friday, June 30, 2017
APPL NO 15/639666
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 3/0611 (20130101)
G06F 3/0659 (20130101)
G06F 3/0683 (20130101)
G06F 9/5077 (20130101)
G06F 12/1081 (20130101) Original (OR) Class
G06F 13/30 (20130101)
G06F 2212/656 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650280 Cox et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) David Cox (Somerville, Massachusetts);  Walter Scheirer (Somerville, Massachusetts);  Samuel Anthony (Cambridge, Massachusetts);  Ken Nakayama (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) David Cox (Somerville, Massachusetts);  Walter Scheirer (Somerville, Massachusetts);  Samuel Anthony (Cambridge, Massachusetts);  Ken Nakayama (Cambridge, Massachusetts)
ABSTRACT In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least its part on the human-weighted loss function.
FILED Thursday, April 11, 2019
APPL NO 16/381291
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00288 (20130101)
G06K 9/627 (20130101)
G06K 9/6263 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650667 Afghah et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona);  The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Michigan);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Fatemeh Afghah (Flagstaff, Arizona);  Abolfazl Razi (Flagstaff, Arizona);  Kayvan Najarian (Flagstaff, Arizona);  Sayedmohammadreza Soroushmehr (Flagstaff, Arizona)
ABSTRACT Implementations of a system for determining the relevancy of a plurality of alarms may include: a plurality of sensors configured to be coupled to a patient, wherein the plurality of sensors is configured to gather physiological data, a medical monitoring device coupled to the plurality of sensors through a telecommunication channel, and wherein the medical monitoring device is configured to determine a physiological state of the patient using the physiological data. The medical monitoring device may be further configured to issue a plurality of alarm states, and a processing unit coupled to the medical monitoring device through a telecommunication channel, is then configured to evaluate the plurality of alarm states, determine the relevancy of each alarm state of the plurality of alarm states, and issue one or more alarms corresponding with each relevant alarm state to a computing device associated with a user.
FILED Monday, November 19, 2018
APPL NO 16/195585
ART UNIT 2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/046 (20130101)
A61B 5/0464 (20130101)
A61B 5/746 (20130101)
A61B 5/14542 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/0453 (20130101)
G08B 29/185 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650982 Jung et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Yeonwoong Jung (Oviedo, Florida);  Nitin Choudhary (Orlando, Florida);  Jayan Thomas (Orlando, Florida)
ABSTRACT A method for the fabrication of h-WO3/WS2 core/shell nanowires and their use in flexible supercapacitor applications. The novel nanowire assemblies exhibit multifold advantages desired for high-performance supercapacitors, including superior material properties and electrode design. The material design principle can be extended to other material systems, implying its great potential for a variety of energy storage devices compatible with emerging flexible and wearable technologies.
FILED Friday, December 08, 2017
APPL NO 15/836338
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/24 (20130101)
H01G 11/28 (20130101) Original (OR) Class
H01G 11/36 (20130101)
H01G 11/48 (20130101)
H01G 11/68 (20130101)
H01G 11/86 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651449 Kotov et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Nicholas A. Kotov (Ann Arbor, Michigan);  Siu-On Tung (Ann Arbor, Michigan);  Szu-Shen Ho (Ann Arbor, Michigan);  Samantha Rahmani (Canton, Michigan)
ABSTRACT Ion conducting membranes based on aramid nanofibers (ANFs) can be prepared using layer-by-layer assembly, sol-gel processing, evaporation, spin coating, doctor blading, or other methods. Porosity is controlled through choice of additives and processing.
FILED Thursday, February 19, 2015
APPL NO 15/120301
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/145 (20130101)
H01M 2/162 (20130101)
H01M 2/1686 (20130101) Original (OR) Class
H01M 4/382 (20130101)
H01M 8/20 (20130101)
H01M 8/188 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101)
H01M 10/0585 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/528 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651461 Bell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents, The University of Texas System (Edinburg, Texas)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents, The University of Texas System (Edinburg, Texas)
INVENTOR(S) Nelson S. Bell (Albuquerque, New Mexico);  Nancy A. Missert (Tijeras, New Mexico);  Karen Lozano (McAllen, Texas);  Yatinkumar N. Rane (Edinburg, Texas)
ABSTRACT A novel lithium battery cathode, a lithium ion battery using the same and processes and preparation thereof are disclosed. The battery cathode is formed by force spinning. Fiber spinning allows for the formation of core-shell materials using material chemistries that would be incompatible with prior spinning techniques. A fiber spinning apparatus for forming a coated fiber and a method of forming a coated fiber are also disclosed.
FILED Tuesday, May 01, 2018
APPL NO 15/968159
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/13 (20130101)
H01M 4/131 (20130101)
H01M 4/139 (20130101)
H01M 4/366 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/1391 (20130101)
H01M 10/052 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652073 Talla et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Vamsi Talla (Seattle, Washington);  Joshua R. Smith (Seattle, Washington);  Shyamnath Gollakota (Seattle, Washington);  Bryce Kellogg (Seattle, Washington)
ABSTRACT Examples described herein include backscatter devices which may transmit orthogonal frequency division multiplexing (OFDM) signals. Techniques for complex analog backscatter are described. Examples of impedance circuitry are described which may be used to provide real and imaginary components of impedance in accordance with inphase and quadrature bits.
FILED Tuesday, April 04, 2017
APPL NO 16/091085
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/0007 (20130101)
H04L 5/0023 (20130101)
H04L 25/0278 (20130101)
H04L 27/0002 (20130101)
H04L 27/26 (20130101)
H04L 27/34 (20130101)
H04L 27/365 (20130101) Original (OR) Class
H04L 27/2626 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652237 Mosenia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Arsalan Mosenia (Princeton, New Jersey);  Susmita Sur-Kolay (Kolkata, India);  Anand Raghunathan (West Lafayette, Indiana);  Niraj K. Jha (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey);  INDIAN STATISTICAL INSTITUTE (Kolkata, India);  PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Arsalan Mosenia (Princeton, New Jersey);  Susmita Sur-Kolay (Kolkata, India);  Anand Raghunathan (West Lafayette, Indiana);  Niraj K. Jha (Princeton, New Jersey)
ABSTRACT A user authentication system for an electronic device for use with a plurality of wireless wearable medical sensors (WMSs) and a wireless base station that receives a biomedical data stream (biostream) from each WMS. The system includes a BioAura engine located on a server, the server has a wireless transmitter/receiver with receive buffers that store the plurality of biostreams, the BioAura engine has a look up stage and a classifier, the classifier generates an authentication output based on the plurality of biostreams, the authentication output authenticates the user's access to the electronic device. The wireless base station has a transmitter/receiver having receive buffers that store the biomedical data from each WMS, the wireless base station has a communication engine that retrieves the biostream from each WMS and transmits the plurality of biostreams to the server.
FILED Monday, February 06, 2017
APPL NO 15/425440
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/021 (20130101)
A61B 5/024 (20130101)
A61B 5/117 (20130101)
A61B 5/0816 (20130101)
A61B 5/14542 (20130101)

Electric Digital Data Processing
G06F 21/32 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 40/63 (20180101)
G16H 40/67 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0861 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 12/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE47983 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Xiaohu Gao (Shoreline, Washington);  Pavel Zrazhevskiy (Redmond, Washington)
ABSTRACT Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label moiety via a double-stranded nucleic acid linker or via an adaptor molecule. The affinity molecule and the label moiety can be linked to different strands of the double-stranded nucleic acid linker. Compositions can be used in any biological assays for detection, identification and/or quantification of target molecules or analytes, including multiplex staining for molecular profiling of individual cells or cellular populations. For example, the compositions can be adapted for use in immunofluorescence, fluorescence in situ hybridization, immunohistochemistry, western blot, and the like.
FILED Thursday, June 28, 2018
APPL NO 16/022679
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 2563/155 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/587 (20130101)
G01N 33/588 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10647081 Hull et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) John R. Hull (Sammamish, Washington);  Cameron Kai-Ming Chen (Seattle, Washington);  John Dalton Williams (Decatur, Alabama)
ABSTRACT A honeycomb thermal insulation structure may comprise a first facesheet, a second facesheet, and a honeycomb core between the first facesheet and the second facesheet. The honeycomb core may include a plurality of honeycomb unit cells each composed of walls having a height and spaced by a distance. The walls of the honeycomb cells may have perforations. The honeycomb thermal insulation structure may further comprise a non-convective gas loaded in the honeycomb unit cells between the walls. A flow of the gas through the perforations may be substantially absent.
FILED Friday, March 31, 2017
APPL NO 15/476188
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/12 (20130101) Original (OR) Class
B32B 3/266 (20130101)
B32B 27/34 (20130101)
B32B 37/146 (20130101)
B32B 38/0008 (20130101)
B32B 2038/047 (20130101)
B32B 2307/304 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647439 Beach
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Raymond F. Beach (North Olmsted, Ohio)
ABSTRACT A hybrid propulsion system for an aircraft is provided that includes a turbine engine, a first electric machine assembly connected to the turbine engine, a second electric machine assembly driven by the first electric machine assembly, and multiple third electric machine assemblies driven by the first electric machine assembly, wherein the multiple third electric machines provide a thrust output to propel the aircraft.
FILED Monday, September 09, 2019
APPL NO 16/564382
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/10 (20130101)
B64D 27/24 (20130101) Original (OR) Class
B64D 2027/026 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 903/96 (20130101)
Y10S 903/906 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647451 Vandervort
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Robert E. Vandervort (Costa Mesa, California)
ABSTRACT A system, method, and apparatus for a vented launch vehicle adaptor (LVA) for a manned spacecraft with a “pusher” launch abort system are disclosed. The disclosed LVA provides a structural interface between a commercial crew vehicle (CCV) crew module/service module (CM/SM) spacecraft and an expendable launch vehicle. The LVA provides structural attachment of the module to the launch vehicle. It also provides a means to control the exhaust plume from a pusher-type launch abort system that is integrated into the module. In case of an on-pad or ascent abort, which requires the module to jettison away from the launch vehicle, the launch abort system exhaust plume must be safely directed away from critical and dangerous portions of the launch vehicle in order to achieve a safe and successful jettison.
FILED Friday, April 28, 2017
APPL NO 15/581979
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/002 (20130101)
B64G 1/12 (20130101)
B64G 1/52 (20130101) Original (OR) Class
B64G 1/641 (20130101)
B64G 1/645 (20130101)
B64G 2001/525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648670 Sadil et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Andreas Sadil (Newington, Connecticut);  Russell B. Hanson (Jupiter, Florida);  Raymond Lamoureux (Marlborough, Connecticut);  Dave J. Hyland (Portland, Connecticut)
ABSTRACT An assembly for a turbine engine includes a combustor bulkhead, a swirler and a mounting strap. The swirler includes a mounting lug and a tubular swirler body that extends along an axis. The mounting lug projects radially out from the swirler body. The mounting strap is attached to the combustor bulkhead. The mounting lug is axially restrained between the combustor bulkhead and the mounting strap.
FILED Monday, August 17, 2015
APPL NO 14/827895
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/20 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/14 (20130101) Original (OR) Class
F23R 3/60 (20130101)
F23R 3/283 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648806 Hesh et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Scott V. Hesh (Greenbackville, Virginia);  Taylor A. Green (Pocomoke City, Maryland);  Joshua T. Yacobucci (Greenbackville, Virginia)
ABSTRACT A microcontroller controlled altimeter includes a microcontroller, a digital altitude pressure sensor with a pressure indicating output coupled to the microprocessor, and at least one Form A solid state relay coupled to the microcontroller, where the microcontroller is configured to provide control signals to the at least one Form A solid state relay to provide an open circuit between normally open and common terminals of the at least one Form A solid state relay if the digital altitude pressure sensor output is less than, or equal to, a setpoint for the at least one Form A relay, and provide continuity between the normally open and common terminals of the at least one Form A solid state relay if the digital altitude pressure sensor output is greater than the setpoint for the at least one Form A relay.
FILED Thursday, June 15, 2017
APPL NO 15/623889
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 5/06 (20130101) Original (OR) Class

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 11/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10648807 Hesh
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Scott V. Hesh (Greenbackville, Virginia)
ABSTRACT The invention disclosed herein includes various embodiments and components of a solid state analog altimeter switch useful for generating switching signals based on altitude determined from barometric pressure. Embodiments of the solid state analog altimeter switch disclosed herein are designed to be extremely accurate, small, robust and inexpensive to produce. Such solid state analog altimeter switches are particularly useful for generating switching events based on predetermined altitudes in sounding rockets.
FILED Tuesday, December 19, 2017
APPL NO 15/846431
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 5/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649081 Rincon et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washinton, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrators of NASA (Washington, District of Columbia)
INVENTOR(S) Rafael F. Rincon (Greenbelt, Maryland);  Kenneth J. Ranson (West River, Maryland);  Temilola E. Fatoyinbo Agueh (Washington, District of Columbia);  Lynn M. Carter (Greenbelt, Maryland)
ABSTRACT The present invention relates to an advanced spaceborne Synthetic Aperture Radar (SAR) system and method that can provide high resolution measurements of the Earth or planetary surface, overcoming limitations in conventional SAR systems, and reduce development costs. The present invention utilizes advanced and innovative techniques, such as software defined waveforms, digital beamforming (DBF) and reconfigurable hardware, to provide radar capabilities not possible with conventional radar instruments, while reducing the radar development cost. The SAR system architecture employs a modular, low power, lightweight design approach to meet stringent spaceborne radar instrument requirements. Thus, the present invention can enable feasible Earth and planetary missions that address a vast number survey goals, including the measurement of ecosystem structure and extent, surface and sub-surface topography, subsurface stratigraphy, soil freeze-thaw, ice sheet composition and extent, glacier depth, and surface water, among many others.
FILED Friday, September 29, 2017
APPL NO 15/719835
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/032 (20130101)
G01S 13/90 (20130101)
G01S 13/904 (20190501) Original (OR) Class
G01S 13/9023 (20130101)
G01S 13/9047 (20190501)
G01S 13/9076 (20190501)

Antennas, i.e Radio Aerials
H01Q 1/288 (20130101)
H01Q 9/0414 (20130101)
H01Q 21/0025 (20130101)
H01Q 21/065 (20130101)
H01Q 23/00 (20130101)
H01Q 25/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10649949 Suarez et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) George Suarez (Columbia, Maryland);  Jeffrey J. Dumonthier (Ashburn, Virginia)
ABSTRACT The invention is a microcircuit configured as a compact, radiation hardened, low-power general purpose I/O expander. The expander may be controlled by an external microcontroller or central processing unit through a serial interface. The expander provides a simple solution to miniaturize static parallel I/O signals using a simplified serial interface such as I2C or SPI.
FILED Tuesday, December 19, 2017
APPL NO 15/846821
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 13/24 (20130101)
G06F 13/1673 (20130101)
G06F 13/4068 (20130101)
G06F 13/4282 (20130101) Original (OR) Class
G06F 2213/0016 (20130101)
G06F 2213/2414 (20130101)

Pulse Technique
H03K 19/0033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651034 Choi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Sang H. Choi (Poquson, Virginia);  Adam J. Duzik (Yorktown, Virginia)
ABSTRACT A method of forming an epitaxial layer on a substrate such as a sapphire wafer that does not readily absorb thermal radiation. The method includes coating a first side surface of the substrate with an energy-absorbing opaque material. The opaque material forms a thermally absorptive coating on the substrate. The coated substrate may be heated to remove contaminants from the thermally absorptive coating. The coated substrate is positioned in a vacuum deposition chamber and heated by directing radiative energy onto the thermally absorptive coating. An epitaxial layer such as GaN or SiGe is formed on a second side surface of the substrate opposite the thermally absorptive coating.
FILED Thursday, March 30, 2017
APPL NO 15/474234
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 23/025 (20130101)
C30B 23/063 (20130101)
C30B 29/52 (20130101)
C30B 29/406 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0242 (20130101)
H01L 21/0254 (20130101)
H01L 21/02376 (20130101)
H01L 21/02422 (20130101)
H01L 21/02532 (20130101)
H01L 21/02658 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651815 Huang
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Wei-Chung Huang (College Park, Maryland)
ABSTRACT A passive phase shifter includes a reference line and a half-wavelength transmission line, where the half-wavelength transmission line is loaded with a perpendicular quarter wavelength rectangular stub and a quarter wavelength radial stub structure connected in series.
FILED Thursday, June 21, 2018
APPL NO 16/014105
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/184 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/36 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 7/21 (20130101) Original (OR) Class
H03H 7/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10651099 Abraham et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David W. Abraham (Croton, New York);  John M. Cotte (New Fairfield, Connecticut)
ABSTRACT Semiconductor devices and electronics packaging methods include integrated circuit chips having redundant signal bond pads along with signal bond pads connected to the same signal port for non-destructive testing of the integrated circuit chips prior to packaging. Electrical testing is made via the redundant signal bond after which qualified integrated circuit chips can be attached to a pristine and bumped final interposer or printed circuit board to provide increased reliability to the assembled electronic package.
FILED Wednesday, November 15, 2017
APPL NO 15/813547
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/0466 (20130101)
G01R 1/0483 (20130101)
G01R 31/2884 (20130101)
G01R 31/2886 (20130101)
G01R 31/2889 (20130101)
G01R 31/2894 (20130101)
G01R 31/31713 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02057 (20130101)
H01L 21/67271 (20130101)
H01L 22/20 (20130101)
H01L 22/32 (20130101) Original (OR) Class
H01L 24/03 (20130101)
H01L 24/06 (20130101)
H01L 24/13 (20130101)
H01L 24/16 (20130101)
H01L 24/81 (20130101)
H01L 2224/131 (20130101)
H01L 2224/131 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/0401 (20130101)
H01L 2224/0567 (20130101)
H01L 2224/0567 (20130101)
H01L 2224/0568 (20130101)
H01L 2224/0568 (20130101)
H01L 2224/0603 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/05099 (20130101)
H01L 2224/05568 (20130101)
H01L 2224/05605 (20130101)
H01L 2224/05605 (20130101)
H01L 2224/05609 (20130101)
H01L 2224/05609 (20130101)
H01L 2224/05611 (20130101)
H01L 2224/05611 (20130101)
H01L 2224/05617 (20130101)
H01L 2224/05617 (20130101)
H01L 2224/05618 (20130101)
H01L 2224/05618 (20130101)
H01L 2224/05624 (20130101)
H01L 2224/05624 (20130101)
H01L 2224/05663 (20130101)
H01L 2224/05663 (20130101)
H01L 2224/05663 (20130101)
H01L 2224/05666 (20130101)
H01L 2224/05666 (20130101)
H01L 2224/05672 (20130101)
H01L 2224/05672 (20130101)
H01L 2224/05676 (20130101)
H01L 2224/05676 (20130101)
H01L 2224/05678 (20130101)
H01L 2224/05678 (20130101)
H01L 2224/05679 (20130101)
H01L 2224/05679 (20130101)
H01L 2224/05681 (20130101)
H01L 2224/05681 (20130101)
H01L 2224/05683 (20130101)
H01L 2224/05683 (20130101)
H01L 2224/05684 (20130101)
H01L 2224/05684 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/16238 (20130101)
H01L 2224/81191 (20130101)
H01L 2224/81192 (20130101)
H01L 2224/81203 (20130101)
H01L 2224/81203 (20130101)
H01L 2224/81815 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/14 (20130101)
H01L 2924/01006 (20130101)
H01L 2924/01057 (20130101)
H01L 2924/01072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651942 Li et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Cheng Li (Palo Alto, California);  Jim Huang (Palo Alto, California);  Ashkan Seyedi (Palo Alto, California);  Marco Fiorentino (Mountain View, California);  Raymond G. Beausoleil (Seattle, Washington)
ABSTRACT One example includes a bias-based Mach-Zehnder modulation (MZM) system. The system includes a Mach-Zehnder modulator to receive and split an optical input signal and to provide an intensity-modulated optical output signal based on a high-frequency data signal to modulate a relative phase of the split optical input signal to transmit data and based on a bias voltage to modulate the relative phase of the split optical input signal to tune the Mach-Zehnder modulator. The system also includes a bias feedback controller to compare a detection voltage associated with the intensity-modulated output signal with a reference voltage to measure an extinction ratio associated with an optical power of the intensity-modulated optical output signal and to adjust the bias voltage based on the comparison to substantially maximize the extinction ratio.
FILED Thursday, February 14, 2019
APPL NO 16/275727
ART UNIT 2637 — Optical Communications
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0102 (20130101)
G02F 1/0123 (20130101)
G02F 1/225 (20130101)
G02F 2001/212 (20130101)

Transmission
H04B 10/503 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10652353 Dinan et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) James Dinan (Hudson, Massachusetts);  Venkata Krishnan (Ashland, Massachusetts);  Srinivas Sridharan (Bangalore, India);  David A. Webb (Groton, Massachusetts)
ABSTRACT Technologies for communication with direct data placement include a number of computing nodes in communication over a network. Each computing node includes a many-core processor having an integrated host fabric interface (HFI) that maintains an association table (AT). In response to receiving a message from a remote device, the HFI determines whether the AT includes an entry associating one or more parameters of the message to a destination processor core. If so, the HFI causes a data transfer agent (DTA) of the destination core to receive the message data. The DTA may place the message data in a private cache of the destination core. Message parameters may include a destination process identifier or other network address and a virtual memory address range. The HFI may automatically update the AT based on communication operations generated by software executed by the processor cores. Other embodiments are described and claimed.
FILED Thursday, September 24, 2015
APPL NO 14/864369
ART UNIT 2449 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 15/17337 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/2852 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10647071 Sherman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armament Research, Development and Engineering Center (ARDEC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Powdermet, Inc. (Euclid, Ohio)
ASSIGNEE(S) Powdermet Inc. (Euclid, Ohio)
INVENTOR(S) Andrew Sherman (Mentor, Ohio);  Haixong Tang (Euclid, Ohio);  Brian Doud (Cleveland Heights, Ohio)
ABSTRACT A composite film having a high dielectric permittivity engineered particles dispersed in a high breakdown strength polymer material to achieve high energy density.
FILED Monday, October 17, 2016
APPL NO 15/294936
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/02 (20130101)
B29C 39/003 (20130101)
B29C 55/04 (20130101)
B29C 55/12 (20130101)
B29C 70/60 (20130101) Original (OR) Class
B29C 70/882 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/162 (20130101)
B29K 2509/02 (20130101)
B29K 2995/0006 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/34 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/12 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 4/18 (20130101)
H01G 4/32 (20130101)
H01G 4/33 (20130101)
H01G 4/186 (20130101)
H01G 4/206 (20130101)
H01G 4/306 (20130101)
H01G 4/1227 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10647938 Lahouij et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland);  UCHICAGO ARGONNE, LLC (Chicago, Illinois);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) PIXELLIGENT TECHNOLOGIES, LLC (Baltimore, Maryland);  UCHICAGO ARGONNE, LLC (Chicago, Illinois);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Imene Lahouij (Philadelphia, Pennsylvania);  Robert Carpick (Philadelphia, Pennsylvania);  Andrew Jackson (Baltimore, Maryland);  Harman Khare (Philadelphia, Pennsylvania);  Nitya Gosvami (Philadelphia, Pennsylvania);  Nicholaos G. Demas (Chicago, Illinois);  Robert A. Erck (Chicago, Illinois);  Aaron C. Greco (Chicago, Illinois);  George R. Fenske (Chicago, Illinois);  Wei Xu (Baltimore, Maryland);  Gregory Cooper (Baltimore, Maryland);  Zhiyun Chen (Baltimore, Maryland)
ABSTRACT The presently disclosed technology relates to a nano-additives to improve the performance of lubricants, oils, and greases. More specifically, the presently disclosed technology relates to applying capped metal oxide nanoparticles, such as capped zirconia nanoparticles, in the lubricants to produce a tribofilms on the lubricating surfaces to provide wear protection to the said surfaces. Also, the interaction of the capped zirconia nanoparticles with other commonly used additives in lubricants may further optimize the performance of the resulting tribofilms.
FILED Wednesday, May 04, 2016
APPL NO 15/569271
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/10 (20130101) Original (OR) Class
C10M 141/10 (20130101)
C10M 171/06 (20130101)
C10M 2201/14 (20130101)
C10M 2203/1006 (20130101)
C10M 2205/00 (20130101)
C10M 2205/0285 (20130101)
C10M 2207/2805 (20130101)
C10M 2209/1033 (20130101)
C10M 2223/045 (20130101)
C10M 2229/025 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2210/04 (20130101)
C10N 2220/082 (20130101)
C10N 2220/084 (20130101)
C10N 2230/58 (20130101)
C10N 2240/02 (20130101)
C10N 2240/04 (20130101)
C10N 2240/10 (20130101)
C10N 2250/10 (20130101)
C10N 2250/121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10648030 Curry et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S) Affymetrix, Inc. (Carlsbad, California);  The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) Affymetrix, Inc. (Carlsbad, California)
INVENTOR(S) John D. Curry (Concord, California);  Heather Koshinsky (El Cerrito, California);  Amanda Kay Lindholm-Perry (Clay Center, Nebraska);  Richard Mark Thallman (Blue Hill, Nebraska)
ABSTRACT The disclosure provides a method of determining the presence or absence of a plurality of target polynucleotides in a sample including combining a sample that may comprise one or more of the plurality of target polynucleotides with a plurality of sets of complementary polynucleotides; incubating the polynucleotides under conditions that allow hybridization of complementary sequences; joining the first and second complementary polynucleotides to form one or more product polynucleotides; and detecting the presence or absence of one or more product polynucleotides to determine the presence or absence of one or more of the plurality of target polynucleotides in the sample.
FILED Monday, January 14, 2013
APPL NO 13/824348
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6862 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2523/109 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2531/137 (20130101)
C12Q 2533/107 (20130101)
C12Q 2533/107 (20130101)
C12Q 2535/131 (20130101)
C12Q 2535/131 (20130101)
C12Q 2535/131 (20130101)
C12Q 2535/131 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5308 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10648003 Padidam
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Intrexon Corporation (Blacksburg, Virginia)
ASSIGNEE(S) Intrexon Corporation (Blacksburg, Virginia)
INVENTOR(S) Malla Padidam (Chalfont, Pennsylvania)
ABSTRACT The present invention provides a method for obtaining site-specific recombination in a eukaryotic cell, the method comprising providing a eukaryotic cell that comprises a first recombination attachment site and a second recombination attachment site; contacting the first and second recombination attachment sites with a prokaryotic recombinase polypeptide, resulting in recombination between the recombination attachment sites, wherein the recombinase polypeptide can mediate recombination between the first and second recombination attachment sites, the first recombination attachment site is a phage genomic recombination attachment site (attP) or a bacterial genomic recombination attachment site (attB), the second recombination site is attB or attP, and the recombinase is selected from the group consisting of a Listeria monocytogenes phage recombinase, a Streptococcus pyogenes phage recombinase, a Bacillus subtilis phage recombinase, a Mycobacterium tuberculosis phage recombinase and a Mycobacterium smegmatis phage recombinase, provided that when the first recombination attachment site is attB, the second recombination attachment site is attP and when the first recombination attachment site is attP, the second recombination attachment site is attB. The invention also describes compositions, vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors and methods of the present invention are also useful in gene therapy applications.
FILED Friday, June 08, 2018
APPL NO 16/003266
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/00 (20130101)
C12N 9/22 (20130101)
C12N 15/52 (20130101)
C12N 15/79 (20130101)
C12N 15/907 (20130101) Original (OR) Class

Enzymes
C12Y 301/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 10651686 White et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard M. White (Berkeley, California);  Zhiwei Wu (Berkeley, California)
ABSTRACT An apparatus for harvesting power from a current carrying conductor without electrically contacting the conductor is provided. The apparatus employs a coil with core and flux concentrators of high magnetic permeability steel that redirect the time-varying magnetic flux of the conductor to interact more strongly with the coil, and increase the coil's output voltage and power. A voltage converter may be used with a DC voltage output that can continually charge batteries or supercapacitors as well as provide energy for sensors, accelerometers, long-range radios to transmit data on local powerline conditions, and LEDs and buzzers. The apparatus may also have powered environmental sensors for measuring the concentrations of airborne particulate matter such as diesel exhaust and smoke, as well as toxic gases, greenhouse gases, allergenic pollens etc. The apparatus has a housing that is oriented and coupled to the conductor with a coupling.
FILED Thursday, August 03, 2017
APPL NO 15/668479
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 38/14 (20130101)
H01F 38/28 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/04 (20130101)
H02J 7/025 (20130101)
H02J 50/12 (20160201) Original (OR) Class

Transmission
H04B 1/02 (20130101)
H04B 3/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10647612 Shi et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S) Xianming Shi (Pullman, Washington);  Gang Xu (Pullman, Washington)
ASSIGNEE(S) Washington State University (Pullman, Washington)
INVENTOR(S) Xianming Shi (Pullman, Washington);  Gang Xu (Pullman, Washington)
ABSTRACT A composition comprising: (a) fly ash cementitious binder; and (b) a chemical activator selected from sodium silicate, potassium silicate, sodium sulfate, sodium phosphate, calcium sulfate, potassium sulfate, potassium phosphate, CaO, Fe2O3, sodium chloride, calcium chloride, fine fraction of concrete waste from construction or demolition, cement kiln dust, or a combination thereof, wherein the fly ash is the only cementitious binder present in the composition and the CaO activator, if present, is present in an amount ≤10 weight percent, based on the total dry weight of the composition.
FILED Friday, August 26, 2016
APPL NO 15/753534
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 12/04 (20130101)
C04B 14/024 (20130101)
C04B 14/026 (20130101)
C04B 14/026 (20130101)
C04B 18/16 (20130101)
C04B 18/162 (20130101)
C04B 18/162 (20130101)
C04B 22/06 (20130101)
C04B 22/16 (20130101)
C04B 22/16 (20130101)
C04B 22/064 (20130101)
C04B 22/064 (20130101)
C04B 22/124 (20130101)
C04B 22/124 (20130101)
C04B 22/143 (20130101)
C04B 22/143 (20130101)
C04B 22/147 (20130101)
C04B 22/147 (20130101)
C04B 28/021 (20130101) Original (OR) Class
C04B 28/021 (20130101)
C04B 2103/10 (20130101)
C04B 2103/0014 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/95 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10646715 Walter et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) James Walter (Oak Park, Illinois);  Donald Thomas (Salinas, California);  Scott Sayers (Hinsdale, Illinois);  Sanjay Singh (Oakbrook Terrace, Illinois);  Raymond Dieter (Glen Ellyn, Illinois)
ABSTRACT The vagus nerve and branches of the vagus nerve are stimulated below the laryngeal nerve branch bifurcation in order to induce desired parasympathetic responses, such as decreased heart rate, without also triggering any adverse sympathetic responses. Stimulating surfaces of an open field bipolar electrode are positioned on or inserted through the pleural membrane overlying the vagus nerve at a location having substantially no cardiac sympathetic fibers adjacent to the vagus nerve. The open field bipolar electrodes can be securable-wire, needle, plate, or any other type of electrode suitable for being secured to the pleural membrane using one or more fastening mechanisms. Electrical stimuli are generated by a stimulator connected to the stimulating surfaces of the open field bipolar electrode by one or more leads.
FILED Thursday, July 23, 2015
APPL NO 15/328386
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0551 (20130101)
A61N 1/0558 (20130101)
A61N 1/36053 (20130101)
A61N 1/36114 (20130101) Original (OR) Class
A61N 1/36171 (20130101)
A61N 1/36175 (20130101)
A61N 1/37235 (20130101)
A61N 1/37247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 10648957 Khusid et al.
FUNDED BY
Department of the Interior (DOI)
Bureau of Reclamation (USBR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Industry-University Cooperative Research Centers (IUCRC)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey);  Government of the United States of America, as Represented by The U.S. Department of Interior, The Bureau of Reclamation (Denver, Colorado)
ASSIGNEE(S) Government of the United States of America, The Bureau of Reclamation (Denver, Colorado);  New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Boris Khusid (New Providence, New Jersey);  Katherine L. Guerra (Golden, Colorado);  Frank Leitz (Evergreen, Colorado);  Yueyang Shen (Ithaca, New York);  Ezinwa O. Elele (Newark, New Jersey);  Qian Lei (Newark, New Jersey)
ABSTRACT A benchtop device flow setup for determining the effectiveness of magnetic treatment of feed water for reducing mineral scaling includes two similar branches, both equipped with a reverse osmosis membrane and a pump that operate in the transient regime at the same flow rate and transmembrane pressure. The flow setup is further fed with a solution at the same level of supersaturation measured in a stirred reactor, however, only one branch exposes the feed to a magnetic field.
FILED Friday, December 22, 2017
APPL NO 15/851776
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Separation
B01D 61/10 (20130101)
B01D 61/025 (20130101)
B01D 2311/04 (20130101)
B01D 2311/04 (20130101)
B01D 2311/24 (20130101)
B01D 2311/243 (20130101)
B01D 2311/246 (20130101)
B01D 2311/2607 (20130101)
B01D 2311/2642 (20130101)
B01D 2311/2642 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/008 (20130101)
C02F 1/441 (20130101)
C02F 1/481 (20130101)
C02F 1/484 (20130101)
C02F 2209/001 (20130101)
C02F 2209/05 (20130101)
C02F 2209/11 (20130101)
C02F 2303/22 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0606 (20130101)
G01N 15/0612 (20130101)
G01N 15/0618 (20130101)
G01N 15/0625 (20130101)
G01N 15/0656 (20130101)
G01N 31/02 (20130101) Original (OR) Class
G01N 33/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 10648863 Ifarraguerri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Leidos, Inc. (Reston, Virginia)
ASSIGNEE(S) Leidos, Inc. (Reston, Virginia)
INVENTOR(S) Augie Ifarraguerri (Arlington, Virginia);  Brian Gorin (Setauket, New York);  J. Frank Camacho (Albuquerque, New Mexico);  Noah Christian (San Diego, California);  Robert Rice (Simi Valley, California)
ABSTRACT A system and process scans a target area at a distance of 3-30 m for one or more materials. Scanning is performed by a coherent transmit beam aimed with the help of a thermal camera. The active source of the beam is a supercontinuum (SC) laser. The transmitted source beam is modulated by a high-speed Fourier-transform spectrometer prior to interaction with the target. Target reflected source beam is detected by an infrared detector, along with a reference portion of the transmitted source beam, as a series of interferograms; passed through a digitizer for digitizing the interferograms; and processed to producing spectrograms, wherein the spectrograms are indicative of one or more materials on the target.
FILED Tuesday, May 15, 2018
APPL NO 15/979534
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/108 (20130101) Original (OR) Class
G01J 3/0275 (20130101)
G01J 3/4537 (20130101)
G01J 2003/423 (20130101)
G01J 2003/2813 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/359 (20130101)
G01N 2201/0612 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 2001/3528 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 10650479 Luckay et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ryan M. Luckay (Washington, District of Columbia);  Robert E. Dixon, Jr. (Washington, District of Columbia);  Jim E. Lee (Washington, District of Columbia)
ABSTRACT Systems and methods of tracking distribution items using hardware components on or in the distribution items. Shippers and recipients of distribution items can track or locate a distribution item, especially a high value item, if the distribution item is lost, misrouted, or delayed.
FILED Thursday, January 04, 2018
APPL NO 15/862003
ART UNIT 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10108 (20130101)
G06K 19/025 (20130101)
G06K 19/07758 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/28 (20130101)
G06Q 50/28 (20130101) Original (OR) Class

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 3/1016 (20130101)
G08B 21/0275 (20130101)

Wireless Communication Networks
H04W 12/00407 (20190101)
H04W 24/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10647449 Wasson et al.
FUNDED BY
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Christopher James Wasson (Torrance, California);  Bradley Whitten Taylor (Lawndale, California);  Richard A. Fowell (Rolling Hills Estates, California)
ABSTRACT According to an embodiment, a system includes a controller configured to determine a set of background light intensities associated with a satellite, where each background light intensity corresponds to at least one of an orientation and a position of a light source relative to the satellite, to determine a set of relative orientations of the light source corresponding to the set of background light intensities, and to generate an image of the satellite based, at least in part, on the determined set of background light intensities and the determined set of relative orientations of the light source.
FILED Wednesday, May 30, 2018
APPL NO 15/993570
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/22 (20130101) Original (OR) Class
B64G 1/1021 (20130101)
B64G 2001/1028 (20130101)

Pictorial Communication, e.g Television
H04N 5/341 (20130101)
H04N 5/2354 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650319 Medford
FUNDED BY
APPLICANT(S) James Redding Medford (Baltimore, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) James Redding Medford (Baltimore, Maryland)
ABSTRACT Systems and methods are provided for flux control of a qubit. A quantum system includes a microwave transmitter configured to provide a continuous microwave tone, and a qubit configured such that a portion of an energy spectrum of the qubit is responsive to an applied flux. The qubit also has an inductive element responsive to the continuous microwave tone to produce a Rabi oscillation within the qubit. A flux source is configured to apply a flux to the qubit.
FILED Friday, February 06, 2015
APPL NO 14/616473
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Transmission
H04B 10/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10650323 Epstein et al.
FUNDED BY
APPLICANT(S) Ryan J. Epstein (Denver, Colorado);  David George Ferguson (Takoma Park, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Ryan J. Epstein (Denver, Colorado);  David George Ferguson (Takoma Park, Maryland)
ABSTRACT Systems and methods are provided for coupling two flux qubits. A quantum circuit assembly includes a first flux qubit, having at least two potential energy minima, and a second flux qubit, having at least two potential energy minima. A system formed by the first and second qubits has at least four potential energy minima prior to coupling, each of the four potential energy minima containing at least one eigenstate of a system comprising the first flux qubit and the second flux qubit. A coupler creates a first tunneling path between a first potential energy minimum of the system and a second potential energy minimum of the system, and a second tunneling path between a third potential energy minimum of the system and a fourth potential energy minimum of the system. The coupler creates the first and second tunneling paths between potential energy minima representing states of equal bit parity.
FILED Wednesday, January 23, 2019
APPL NO 16/255588
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Pulse Technique
H03K 19/195 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10651233 Hartman et al.
FUNDED BY
APPLICANT(S) Jeffrey David Hartman (Severn, Maryland);  Justin C. Hackley (Catonsville, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Jeffrey David Hartman (Severn, Maryland);  Justin C. Hackley (Catonsville, Maryland)
ABSTRACT A superconducting structure includes a first superconducting device having a plurality of first superconducting contact pads disposed on a top side of a first superconducting device, a second superconducting device having a plurality of second superconducting contact pads disposed on a bottom side of a second superconducting device, and a plurality of superconducting bump structures with a given bump structure coupling respective superconducting contact pads of the plurality of first superconducting contact pads and the second plurality of superconducting pads to one another to bond the first superconducting device to the second superconducting device. Each superconducting bump structure includes a first under bump metallization (UBM) layer disposed on the top surface of a given superconducting contact pad, a second UBM layer disposed on the top surface of a given superconducting contact pads, and a superconducting metal layer coupling the first UBM layer to the second UBM layer.
FILED Tuesday, August 21, 2018
APPL NO 16/107321
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 24/13 (20130101)
H01L 24/81 (20130101)
H01L 27/18 (20130101) Original (OR) Class
H01L 39/24 (20130101)
H01L 2224/0401 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13144 (20130101)
H01L 2224/13166 (20130101)
H01L 2224/13169 (20130101)
H01L 2224/13171 (20130101)
H01L 2224/16148 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

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THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 12, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

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THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

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Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
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FILED
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

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CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

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The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

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You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200512.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital