FedInvent™ Patents
Patent Details for Tuesday, May 19, 2020
This page was updated on Monday, March 27, 2023 at 06:05 AM GMT
Department of Health and Human Services (HHS)
| US 10653123 | Haining et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | William N. Haining (Newton, Massachusetts); Arlene H. Sharpe (Brookline, Massachusetts); Jernej Godec (Brookline, Massachusetts) |
| ABSTRACT | The invention provides methods and compositions for perturbing gene expression in hematopoietic cell lineages in vivo. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 15/314251 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2227/105 (20130101) A01K 2267/025 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 49/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) C12N 5/0636 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2740/15041 (20130101) C12N 2740/15043 (20130101) C12N 2840/002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5052 (20130101) G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653140 | Davies |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | David G. Davies (Binghamton, New York) |
| ABSTRACT | One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: H3C—(CH2)n—CHm where |
| FILED | Thursday, July 18, 2013 |
| APPL NO | 13/945207 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/02 (20130101) A01N 37/06 (20130101) Original (OR) Class A01N 37/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/361 (20130101) A61K 8/4973 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653321 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Bin Huang (St. Louis, Missouri); Jun Xia (St. Louis, Missouri); Konstantin Maslov (St. Louis, Missouri); Mark Anastasio (St. Louis, Missouri) |
| ABSTRACT | Systems and methods for improving limited-view photoacoustic tomography using an acoustic reflector are described. In particular, an acoustic reflector and ultrasonic transducer array are integrated to provide a virtual array that enhances the field of view of the ultrasonic transducer array, thereby improving the quality of photoacoustic tomography images obtained using the systems and methods described herein. |
| FILED | Wednesday, November 12, 2014 |
| APPL NO | 15/036303 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Original (OR) Class A61B 8/4245 (20130101) A61B 8/4483 (20130101) A61B 2503/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653346 | Zarandi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Soroush Mohammad Mirzaei Zarandi (La Habra, California); Bruce J. Tromberg (Irvine, California); Thomas D. O'Sullivan (Laguna Hills, California); Siavash Sedighzadeh Yazdi (Irvine, California); Albert Cerussi (Cupertino, California) |
| ABSTRACT | A low cost portable high speed quantitative system for diffuse optical spectroscopic imaging of human tissue. The hybrid system (CWFD) can measure absolute optical properties from 660 nm to 980 nm and recover all tissue chromophore concentrations. The standalone FD module can be utilized to measure scattering at every measurement and recover deoxygenated and oxygenated hemoglobin concentrations. The CW module can operate concurrently with the FD module to also measure water and lipid. The high temporal resolution and large signal-to-noise ratio of the CWFD system may be used to explore tissue oximetry, vascular occlusion, and paced breathing models to measure and analyze tissue hemodynamics response to changes in blood flow. Continuous monitoring of vasculature response to various modified blood perfusion conditions can provide information about local tissue metabolism and physiological state (dysfunction). |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416942 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0816 (20130101) A61B 5/02416 (20130101) A61B 5/7278 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653371 | Heuscher et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Dominic Heuscher (Salt Lake City, Utah); Frederic Noo (Salt Lake City, Utah) |
| ABSTRACT | A collimator for a computed tomography imaging device can include first and second leaves positioned on opposing sides of a primary radiation delivery window. The first and second leaves can include first and second gratings having a plurality of attenuating members with a plurality of secondary radiation delivery windows extending between adjacent attenuating members. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 14/848102 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/06 (20130101) A61B 6/027 (20130101) A61B 6/032 (20130101) A61B 6/469 (20130101) A61B 6/481 (20130101) A61B 6/488 (20130101) A61B 6/507 (20130101) A61B 6/542 (20130101) A61B 6/4035 (20130101) Original (OR) Class A61B 6/5205 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653381 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | KINETICOR, INC. (Honolulu, Hawaii); THE UNIVERSITY OF HAWAII (Honolulu, Hawaii); THE QUEEN'S MEDICAL CENTER (Honolulu, Hawaii) |
| ASSIGNEE(S) | Kineticor, Inc. (Honolulu, Hawaii); The University of Hawaii (Honolulu, Hawaii); The Queen's Medical Center (Honolulu, Hawaii) |
| INVENTOR(S) | Jeffrey N. Yu (Honolulu, Hawaii); Thomas Michael Ernst (Honolulu, Hawaii) |
| ABSTRACT | The disclosure herein provides methods, systems, and devices for tracking motion of a patient or object of interest during biomedical imaging and for compensating for that motion in the biomedical imaging scanner and/or the resulting images to reduce or eliminate motion artifacts. In an embodiment, a motion tracking system is configured to overlay tracking data over biomedical imaging data in order to display the tracking data along with its associated image data. In an embodiment, a motion tracking system is configured to overlay tracking data over biomedical imaging data in order to display the tracking data along with its associated image data. In an embodiment, one or more detectors are configured to detect images of a patient, and a detector processing interface is configured to analyze the images to estimate motion or movement of the patient and to generate tracking data describing the patient's motion. The detector processing interface is configured to send the tracking data to a scanner controller to enable adjustment of scanning parameters in real-time in response to the patient's motion. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/696920 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/721 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/0492 (20130101) A61B 6/527 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/283 (20130101) G01R 33/5608 (20130101) G01R 33/56509 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/73 (20170101) G06T 7/207 (20170101) G06T 2200/04 (20130101) G06T 2207/10072 (20130101) G06T 2207/30004 (20130101) G06T 2211/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653650 | Chandraratna et al. |
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| FUNDED BY |
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| APPLICANT(S) | Io Therapeutics, Inc. (Santa Ana, California); Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Io Therapeutics, Inc. (Houston, Texas); Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Roshantha A. Chandraratna (Laguna Hills, California); Ethan Dmitrovsky (Hanover, New Hampshire); Elizabeth Nowak (West Lebanon, New Hampshire); Randolph Noelle (Plainfield, New Hampshire); Martin E. Sanders (Santa Ana, California) |
| ABSTRACT | The present specification provides RXR agonists with both remyelination promotion and immunomodulatory activities, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat a demyelination-related disorder by both promoting remyelination of neurons and modulating the immune system. |
| FILED | Monday, October 06, 2014 |
| APPL NO | 14/507730 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/192 (20130101) Original (OR) Class A61K 31/216 (20130101) A61K 31/343 (20130101) A61K 31/353 (20130101) A61K 31/4704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653676 | D'Andrea et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Alan D. D'Andrea (Winchester, Massachusetts); Gregory D. Cuny (Houston, Texas); Ross L. Stein (Cambridge, Massachusetts); Marcie Glicksman (Winchester, Massachusetts); April Case (Watertown, Massachusetts); Jun Xian (Sharon, Massachusetts); David Wilson (Lawrence, Kansas); Min Huang (Shanghai, China PRC) |
| ABSTRACT | Provided are small molecule inhibitors of ubiquitin specific protease 1 (USP1) activity and methods for their use in treating and characterizing cancers. The small molecule USP1 inhibitors of the invention are particularly useful in the treatment of cancers that are resistant to DNA cross-linking agents. |
| FILED | Thursday, November 03, 2016 |
| APPL NO | 15/342175 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/423 (20130101) Original (OR) Class A61K 31/472 (20130101) A61K 31/4725 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 225/30 (20130101) Heterocyclic Compounds C07D 217/24 (20130101) C07D 263/60 (20130101) C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653679 | Abramovitch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Robert Abramovitch (East Lansing, Michigan); Benjamin K. Johnson (Lansing, Michigan); Christopher J. Colvin (East Lansing, Michigan) |
| ABSTRACT | The present disclosure provides, among other things, compositions and methods useful for inhibiting bacteria, such as Mycobacterium tuberculosis. These compositions and methods find many uses in medicine and research, e.g., treating subjects afflicted with active or latent bacterial infections. The compositions described herein are also useful for decontaminating surfaces (e.g., surgical tools or implants). |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/572121 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Original (OR) Class A61K 45/06 (20130101) Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653682 | Suto et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Vandana V. Gupta (Birmingham, Alabama); Bini Mathew (Hoover, Alabama); Joanne Murphy-Ullrich (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is concerned with oxadiazole and thiadiazole analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, and methods of treating fibrotic conditions using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172312 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/433 (20130101) Original (OR) Class A61K 31/4245 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653698 | Yeager et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mezzion Pharma Co., Ltd. (Seoul, South Korea); Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Mezzion Pharma Co., Ltd. (Seoul, South Korea); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James L. Yeager (Lake Forest, Illinois); David J. Goldberg (Philadelphia, Pennsylvania); Stephen M. Paridon (Strafford, Pennsylvania) |
| ABSTRACT | The present invention relates generally to the field of using udenafil or a pharmaceutically acceptable salt thereof in patients who have undergone the Fontan operation. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 15/887523 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/519 (20130101) A61K 31/522 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653714 | de la Motte et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Carol de la Motte (Broadview Heights, Ohio); Sean Kessler (Rocky River, Ohio); David Richard Hill (Ypsilanti, Michigan) |
| ABSTRACT | Compositions and methods are provided for enhancing the expression of human beta defensin 2 (HBD2) in human colon epithelium cells. The method comprises orally administering a composition comprising hyaluronan, where said hyaluronan has a molecular weight within the range of about 35 kDa. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/798848 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/19 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/728 (20130101) Original (OR) Class A61K 38/40 (20130101) A61K 47/61 (20170801) A61K 47/644 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653727 | Myles et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Ian Antheni Myles (Bethesda, Maryland); Sandip K. Datta (Bethesda, Maryland) |
| ABSTRACT | Pharmaceutical compositions are disclosed that includes a therapeutically effective amount of a purified viable Gram negative bacteria and a pharmaceutically acceptable carrier. The pharmaceutical compositions are formulated for topical administration. Methods of treating atopic dermatitis using these pharmaceutical compositions are also disclosed. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522379 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 35/74 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653728 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Laura M. Cox (Brookline, Massachusetts); Martin J. Blaser (New York, New York) |
| ABSTRACT | The application relates to methods based on modulating mammalian intestinal microbiota and related probiotic and prebiotic compositions. Specifically, the application relates to the use of novel bacterial genera Ileibacterium and Dubosiella, including their species I. valens (I. valens) and Dubosiella newyorkensis (D. newy), respectively, and closely related OTUs within the family Erysipelotrichaceae that resemble either Ileibacterium spp. or Dubosiella spp. with 90% 16S rRNA sequence identity, for modulating weight and intestinal inflammation and immunity (including modulating intestinal immune gene expression such as, e.g., modulating expression of RORγT, IL-17A, IL-17F, RegIIIγ, Relmβ, and Defβ), as well as for treatment and diagnosis of (i) obesity and related conditions such as metabolic syndrome and diabetes mellitus; (ii) allergic and autoimmune diseases, and (iii) gastrointestinal disorders (such as, e.g., inflammatory bowel disease (IBD), ulcerative colitis, Crohn's disease, and celiac disease). |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786483 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653747 | Anantharamaiah et al. |
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| FUNDED BY |
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| APPLICANT(S) | UAB RESEARCH FOUNDATION (Birmingham, Alabama); LIPIMETIX DEVELOPMENT, LLC (Natick, Massachusetts) |
| ASSIGNEE(S) | UAB RESEARCH FOUNDATION (Birmingham, Alabama); LIPIMETIX DEVELOPMENT, LLC (Natick, Massachusetts) |
| INVENTOR(S) | Gattadahalli M. Anantharamaiah (Birmingham, Alabama); Dennis Goldberg (Sudbury, Massachusetts) |
| ABSTRACT | Disclosed are synthetic apolipoprotein E-mimicking peptides, derivatives thereof, and related peptides, which are useful as therapeutic agents for reducing plasma cholesterol; synthetic methods of making the peptides; pharmaceutical compositions comprising the peptides, and methods of treating lipid and metabolic disorders using the disclosed synthetic apolipoprotein E-mimicking peptides and compositions thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 15/329735 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 9/10 (20180101) Peptides C07K 14/775 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653749 | Ghosh |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Pradipta Ghosh (San Diego, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Pradipta Ghosh (San Diego, California) |
| ABSTRACT | The invention provides cell-permeable Ga-Interacting Vesicle associated protein (GIV)-derived peptides and their use for treatment of diverse diseases. The invention further provides C-terminus of Ga-Interacting Vesicle associated protein (GIV-CT)-based peptides and GIV-CT encoding vectors and methods of use thereof, for successfully manipulating the diverse pathophysiologic processes in which GIV has been implicated. In one aspect, the invention provides cell-permeable peptides PTD-GIV-CT comprising (i) a peptide transduction domain (PTD) and (ii) a C-terminus of Ga-Interacting Vesicle associated protein (GIV-CT) or a mutant thereof. In one embodiment, said peptides are capable of activating Gi downstream of receptor tyrosine kinases (RTKs). The invention also provides pharmaceutical compositions comprising one or more of the peptides of the invention as well as vectors encoding such peptides. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/565192 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/179 (20130101) Original (OR) Class A61K 38/1741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/005 (20130101) C07K 14/4703 (20130101) C07K 14/4705 (20130101) C07K 19/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/10 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/33 (20130101) C07K 2319/43 (20130101) C07K 2319/74 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653750 | Lockwood et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Charles Joseph Lockwood (Tampa, Florida); Umit Ali Kayisli (Wesley Chapel, Florida); Murat Basar (New Haven, Connecticut); Ozlem Guzeloglu-Kayisli (Wesley Chapel, Florida); Nihan Semerci (Tampa, Florida); Frederick Schatz (Tampa, Florida) |
| ABSTRACT | The present invention concerns compositions and methods for inhibition of abnormal uterine bleeding (AUB), such as that associated with use of long-acting progestin-only contraceptives (LAPCs). An aspect of the invention concerns compositions comprising chemokine (C-C motif) ligand 2 (CCL2), or a biologically active fragment thereof, which may administered to subjects for inhibition of AUB. Another aspect of the invention concerns methods for inhibiting AUB, comprising administering an effective amount of CCL2, or a biologically active fragment thereof, to a subject in need thereof. Another aspect of the invention concerns a kit for inhibiting AUB. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/561158 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 31/57 (20130101) A61K 38/195 (20130101) Original (OR) Class A61K 38/195 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653752 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Bolder Bio Technology, Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox (Louisville, Colorado); Christie M. Orschell (Indianapolis, Indiana) |
| ABSTRACT | Methods and compositions for the use of long-acting hematopoietic factor protein analogs for accelerating hematopoietic recovery in subjects who have been or will be exposed to radiation are disclosed. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997406 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/27 (20130101) A61K 38/193 (20130101) A61K 38/2073 (20130101) Original (OR) Class A61K 47/60 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653756 | Turtle et al. |
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| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Cameron J. Turtle (Seattle, Washington); Stanley R. Riddell (Sammamish, Washington) |
| ABSTRACT | This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8+ T cell subsets (CMhi and EMhi) with high surface expression of CD161 and/or IL-18Rα and the capacity to rapidly efflux the fluorescent dye Rh123. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903214 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/00 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/515 (20130101) A61K 2039/572 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 2501/599 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 2333/54 (20130101) G01N 2333/70557 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653760 | Lucas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Alexandra Rose Lucas (Gainesville, Florida) |
| ABSTRACT | Disclosed here are polypeptides, derived from the Myxomavirus-derived secreted glycoprotein, M-T7, comprising point mutations that interfere with chemokine-glycosaminoglycan binding. Compositions containing such M-T7 derived polypeptides with point mutations are therefore useful in preventing, blocking and/or reducing rejection of a transplant. |
| FILED | Thursday, July 07, 2016 |
| APPL NO | 15/742092 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001 (20130101) Original (OR) Class A61K 39/275 (20130101) A61K 2039/58 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653770 | Harrison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stephen C. Harrison (Brighton, Massachusetts); Bing Chen (Chestnut Hill, Massachusetts); Dan Barouch (Boston, Massachusetts); Joseph P. Nkolola (Watertown, Massachusetts); Michael Scott Seaman (West Roxbury, Massachusetts) |
| ABSTRACT | Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/579025 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16051 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653775 | Schwarz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Edward M. Schwarz (Rochester, New York); Mark A. Sullivan (Fairport, New York); John L. Daiss (Rochester, New York) |
| ABSTRACT | The present invention is directed to a monoclonal antibody that binds specifically to a Staphylococcus aureus glucosaminidase and inhibits in vivo growth of S. aureus. Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating S. aureus infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/221442 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) A61F 2/30 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/1271 (20130101) C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653786 | Kaplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Xiaoqin Wang (Winchester, Massachusetts); Vijay John (New Orleans, Louisiana); Noshir Pesika (New Orleans, Louisiana); Rubo Zheng (New Orleans, Louisiana) |
| ABSTRACT | Provided herein relates to compositions and methods for lubrication of a surface. The surface amenable to the compositions and methods described herein can be a non-biological surface, a biological surface, or a combination thereof. In some embodiments, the composition comprising a phospholipid-coated silk microsphere can be used for lubrication of a surface. In some embodiments, the composition comprising a phospholipid-coated silk microsphere can be used for joint lubrication, e.g., for treatment of joint disorders such as arthritis. |
| FILED | Thursday, April 25, 2013 |
| APPL NO | 14/390351 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1617 (20130101) A61K 45/06 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/28 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/3645 (20130101) A61L 2300/622 (20130101) A61L 2400/10 (20130101) A61L 2430/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653789 | Camacho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/556798 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653793 | Goldenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | David M. Goldenberg (Mendham, New Jersey); Serengulam V. Govindan (Summit, New Jersey) |
| ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/143680 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7088 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 41/0038 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6851 (20170801) Original (OR) Class A61K 47/6855 (20170801) A61K 47/6859 (20170801) A61K 47/6863 (20170801) A61K 47/6889 (20170801) A61K 51/1045 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) A61N 2005/1021 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3076 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653800 | McNamara, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); INTEGRATED DNA TECHNOLOGIES, INC. (Coralville, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); Integrated DNA Technologies, Inc. (Coralville, Iowa) |
| INVENTOR(S) | James O. McNamara, II (Iowa City, Iowa); Katie R. Flenker (Iowa City, Iowa); Lingyan Huang (Coralville, Iowa); Alexander R. Horswill (Iowa City, Iowa); Mark A. Behlke (Coralville, Iowa); Frank J. Hernandez (Iowa City, Iowa) |
| ABSTRACT | The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., ribonuclease) substrates, and probes and compositions useful in detection assays. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 15/430217 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0052 (20130101) A61K 49/0054 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/689 (20130101) C12Q 1/6818 (20130101) C12Q 1/6823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/569 (20130101) G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653801 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Zheng Han (Cleveland, Ohio); Hui Zhu (Cleveland, Ohio) |
| ABSTRACT | A compound includes at least one targeting peptide coupled to a detectable moiety. The targeting peptide binds to EDB-FN or EDA-FN and includes at least one of amino acid sequence selected from the group consisting of SEQ ID NOs: 1-30. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/188881 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) A61K 49/0056 (20130101) Original (OR) Class A61K 51/082 (20130101) Peptides C07K 7/06 (20130101) C07K 14/78 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/78 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653803 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Liangfang Zhang (San Diego, California) |
| ABSTRACT | Living cells, such as red blood cells (RBCs) modified with functional micromotors with the aid of ultrasound propulsion and magnetic guidance. Iron oxide nanoparticles are loaded into the RBCs, where their asymmetric distribution within the cells results in a net magnetization, thus enabling magnetic alignment and guidance under acoustic propulsion. The RBC motors display efficient guided and prolonged propulsion in various biological fluids, including undiluted whole blood. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/356977 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/5094 (20130101) A61K 9/5115 (20130101) A61K 35/18 (20130101) A61K 41/00 (20130101) A61K 47/6901 (20170801) A61K 49/0067 (20130101) A61K 49/0097 (20130101) Original (OR) Class A61K 2035/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653805 | Reiner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Thomas Reiner (Weehawken, New Jersey); Edmund J. Keliher (Topsfield, Massachusetts); Ralph Weissleder (Peabody, Massachusetts) |
| ABSTRACT | This document relates to compounds useful for targeting PARP1. Also provided herein are methods for using such compounds to detect and image cancer cells. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/147370 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0021 (20130101) A61K 51/0459 (20130101) Original (OR) Class A61K 51/1251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653806 | Pomper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Martin G. Pomper (Baltimore, Maryland); Sangeeta Ray (Ellicott City, Maryland); Ronnie C. Mease (Fairfax, Virginia); Hassan Shallal (Baltimore, Maryland) |
| ABSTRACT | The present invention provides bivalent and multivalent ligands with a view to improving the affinity and pharmacokinetic properties of a urea class of PSMA inhibitors. The compounds and their synthesis can be generalized to multivalent compounds of other target antigens. Because they present multiple copies of the pharmacophore, multivalent ligands can bind to receptors with high avidity and affinity, thereby serving as powerful inhibitors. The modular multivalent scaffolds of the present invention, in one or more embodiments, contains a lysine-based (α-, ε-) dialkyne residue for incorporating two or more antigen binding moieties, such as PSMA binding Lys-Glu urea moieties, exploiting click chemistry and one or more additional lysine residues for subsequent modification with an imaging and/or therapeutic nuclides or a cytotoxic ligands for tumor cell killing. |
| FILED | Monday, February 05, 2018 |
| APPL NO | 15/888634 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 51/088 (20130101) Original (OR) Class A61K 51/0482 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 5/0217 (20130101) C07K 5/0815 (20130101) C07K 5/0821 (20130101) C07K 5/06086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653813 | Stewart |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Russell J. Stewart (Salt Lake City, Utah) |
| ABSTRACT | Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 15/833157 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/06 (20130101) A61L 24/10 (20130101) A61L 24/0015 (20130101) A61L 24/043 (20130101) A61L 24/043 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/54 (20130101) A61L 2300/62 (20130101) A61L 2430/16 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 8/06 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654715 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioNano Genomics, Inc. (San Diego, California) |
| ASSIGNEE(S) | BIONANO GENOMICS, INC. (San Diego, California) |
| INVENTOR(S) | Han Cao (San Diego, California); Michael David Austin (San Diego, California); Parikshit A. Deshpande (San Diego, California); Mark Kunkel (San Diego, California); Alexey Y. Sharonov (San Diego, California); Michael Kochersperger (San Diego, California) |
| ABSTRACT | Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided. |
| FILED | Tuesday, December 20, 2016 |
| APPL NO | 15/385302 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/10 (20130101) B01L 2200/0663 (20130101) B01L 2200/0689 (20130101) B01L 2300/168 (20130101) B01L 2300/0816 (20130101) B01L 2300/0851 (20130101) B01L 2300/0858 (20130101) B01L 2300/0864 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) B01L 2400/0442 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) Original (OR) Class B81C 2201/019 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/0346 (20130101) G01N 2021/6439 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4981 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654785 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Travis J. Williams (Los Angeles, California); Zhiyao Lu (Duarte, California); Valery Cherepakhin (Los Angeles, California) |
| ABSTRACT | Conversion of vegetable-derived triglycerides to fatty acid methyl esters (FAMEs) is a popular approach to the generation of biodiesel fuels and the basis of a growing industry. Drawbacks of the strategy are that (a) the glycerol backbone of the triglyceride is discarded as waste in this synthesis, and (2) many natural triglycerides are multiply-unsaturated or fully saturated, giving inferior performance and causing engine problems with long-term use. Here, we show that catalysis by iridium complex 1 can address both of these problems through selective reduction of triglycerides high in polyunsaturated fatty esters to FAMEs with high oleate concentration. This is realized using hydrogen imbedded in the triglyceride backbone, concurrently generating lactate as a value-added C3 product. Additional methanol or glycerol as a hydrogen source enables reduction of corn and soybean oils to >80% oleate. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/193590 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) Acyclic or Carbocyclic Compounds C07C 51/09 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 17/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654801 | El-Deiry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wafik S. El-Deiry (Philadelphia, Pennsylvania); Xiaobing Tian (Philadelphia, Pennsylvania); Shengliang Zhang (Philadelphia, Pennsylvania) |
| ABSTRACT | Prodigiosin analogs which reactivate the p53 pathway are provided, as well as compositions of these compounds, and methods for reactivation of the p53 pathway using these compounds are provided. The prodigiosin analogs may be used to treat cancer in which p53 mutation plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among others. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 16/091701 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4025 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 207/36 (20130101) Original (OR) Class C07D 403/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654807 | David et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University Of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Sunil Abraham David (St. Paul, Mississippi); Hari Prasad Kokatla (Telangana, India); Diptesh Sil (Gujarat, India); Subbalakshmi Malladi (Lawrence, Kansas); Lauren Miranda Fox (Lawrence, Kansas) |
| ABSTRACT | Compounds described herein can be used for therapeutic purposes. The compounds can be TLR agonists, such as TLR8 agonists. The compounds can be included in pharmaceutical compositions and used for therapies were being a TLR8 agonist is useful. The pharmaceutical compositions can include any ingredients, such as carries, diluents, excipients, fillers or the like that are common in pharmaceutical compositions. The compounds can be those illustrated or described herein as well as derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combinations thereof. As such, the compounds can be used as adjuvants in vaccines as well as for other therapeutic purposes described herein. The compounds can have any one of the formulae described herein or derivative thereof. |
| FILED | Friday, December 19, 2014 |
| APPL NO | 15/106488 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 39/39 (20130101) A61K 2039/55 (20130101) A61K 2039/57 (20130101) A61K 2039/55511 (20130101) Heterocyclic Compounds C07D 215/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654811 | Andersen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada) |
| ASSIGNEE(S) | The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada) |
| INVENTOR(S) | Raymond John Andersen (Vancouver, Canada); Javier Garcia Fernandez (Asturias, Spain); Kunzhong Jian (Vancouver, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada) |
| ABSTRACT | Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided. |
| FILED | Wednesday, January 13, 2016 |
| APPL NO | 15/543389 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 31/4192 (20130101) A61K 31/4192 (20130101) A61K 31/5375 (20130101) A61K 31/5375 (20130101) A61K 45/06 (20130101) A61K 51/0453 (20130101) A61K 51/0459 (20130101) A61K 51/0463 (20130101) A61K 51/0465 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 233/60 (20130101) C07D 249/04 (20130101) Original (OR) Class C07D 265/30 (20130101) C07D 295/084 (20130101) C07D 295/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654841 | Benner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven A Benner (Gainesville, Florida); Nicole A Leal (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A Benner (Gainesville, Florida); Nicole A Leal (Gainesville, Florida) |
| ABSTRACT | This invention claims processes that comprise the appending of nucleotides having a 3′-ONH2 moiety to the 3′-ends of oligonucleotide primers using 3′-deoxynucleoside triphosphates of 2′-deoxynucleoside derivatives that have, instead of a 3′-OH moiety, a 3′-ONH2 moiety, where the nucleotides contain non-standard nucleobases. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786086 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 413/14 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2310/33 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654847 | Lindsley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Michael R. Wood (Westwood, Massachusetts); Corey R. Hopkins (Nolensville, Tennessee); Bruce J. Melancon (South Bend, Indiana); Michael S. Poslusney (Owings Mills, Maryland); Darren W. Engers (Brentwood, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChR M1); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902547 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 275/06 (20130101) C07D 401/10 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 405/10 (20130101) C07D 417/10 (20130101) C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654869 | Tse-Dinh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida International University Board of Trustees (Miami, Florida); University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida); UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Yuk-Ching Tse-Dinh (Coral Gables, Florida); Dianqing Sun (Hilo, Hawaii) |
| ABSTRACT | The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291408 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) Heterocyclic Compounds C07D 498/04 (20130101) Original (OR) Class C07D 498/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654875 | McKinlay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Colin J. McKinlay (Alberton, California); Paul A. Wender (Menlo Park, California); Robert M. Waymouth (Palo Alto, California) |
| ABSTRACT | Guanidinium-rich oligophosphotriesters transporter compounds and methods of making and using the same are provided. Also provided are pharmaceutical compositions that include the subject transporter compounds, where the transporter can be joined to a cargo of interest, and is formulated with a pharmaceutically acceptable excipient. Formulations may be provided in a unit dose, where the dose provides an amount of the compound effective to afford a desired therapeutic effect. Methods of using the subject transporter compounds to deliver a cargo moiety to a cell are provided, where the method can include contacting a target cell with the transporter compound. The subject methods can be performed in vitro or in vivo. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/773725 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 47/548 (20170801) A61K 47/605 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) C07F 9/098 (20130101) Original (OR) Class C07F 9/65512 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654898 | Collins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Serices (Bethesda, Maryland) |
| INVENTOR(S) | Peter Collins (Silver Spring, Maryland); Bo Liang (Boyds, Maryland); Shirin Munir (Bethesda, Maryland); Anne Schaap Nutt (Austin, Texas); Ursula Buchholz (Silver Spring, Maryland); Natalie Mackow (East Setauket, New York); Peter Kwong (Washington, District of Columbia); Barney Graham (Rockville, Maryland); Jason McLellan (Norwich, Vermont) |
| ABSTRACT | Recombinant paramyxoviruses including a viral genome encoding a heterologous gene are provided. In several embodiments, the recombinant paramyxovirus is a recombinant parainfluenza virus, such as a recombinant PIV3 including a viral genome encoding a heterologous respiratory syncytial virus F ectodomain linked to the transmembrane domain and the cytoplasmic tail of the F protein from the PIV3. Nucleic acid molecules including the genome of a recombinant paramyxoviruses are also provided. The recombinant viruses may advantageously be used in vaccine formulations, such as for vaccines against parainfluenza virus and respiratory syncytial virus. |
| FILED | Wednesday, January 20, 2016 |
| APPL NO | 15/545218 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/03 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/00022 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) C12N 2760/18622 (20130101) C12N 2760/18634 (20130101) C12N 2760/18641 (20130101) C12N 2760/18643 (20130101) C12N 2760/18671 (20130101) C12N 2760/18722 (20130101) C12N 2760/18734 (20130101) C12N 2760/18741 (20130101) C12N 2760/18743 (20130101) C12N 2760/18771 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654902 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | June R. Scott (Atlanta, Georgia); Dorothea Zähner (Atlanta, Georgia); Bernard Quigley (Atlanta, Georgia) |
| ABSTRACT | Provided herein are methods and compositions for the display of polypeptides of interest on the tip of pili of Gram-positive bacteria. According to the present invention, the polypeptide of interest is amino terminal to a Gram-positive bacterial pilus tip protein or an active variant or fragment thereof, wherein the active variant or fragment comprises a cleaved cell wall sorting signal (CWSS) motif. The Gram-positive bacterium displaying a polypeptide of interest on the tip of pili that are disclosed herein are useful, for example, in methods for immunizing a subject with an antigen and methods for removing contaminants from a composition. |
| FILED | Tuesday, October 14, 2014 |
| APPL NO | 14/513797 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/09 (20130101) A61K 39/092 (20130101) A61K 39/0258 (20130101) A61K 2039/523 (20130101) A61K 2039/6068 (20130101) Peptides C07K 14/245 (20130101) C07K 14/315 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/035 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) C12N 15/62 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Enzymes C12Y 304/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654905 | Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); United States Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health (Bethesda, Maryland) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); National Institutes of Health, a component of the US Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christopher K. Garcia (Menlo Park, California); Suman Mitra (Bethesda, Maryland); Warren J. Leonard (Bethesda, Maryland); Aaron M. Ring (Palo Alto, California) |
| ABSTRACT | Novel human interleukin-2 (IL-2) muteins or variants thereof are provided. In particular, provided are IL-2 muteins that have an increased binding capacity for IL-2Rβ receptor and a decreased binding capacity for IL-2Rγc receptor, as compared to wild-type IL-2. Such IL-2 muteins are useful, for example, as IL-2 partial agonist and antagonists in applications where reduction or inhibition of one or more IL-2 and/or IL-15 functions is useful (e.g., in the treatment of graft versus host disease (GVHD) and adult T cell leukemia). Also provided are nucleic acids encoding such IL-2 muteins, methods of making such IL-2 muteins, pharmaceutical compositions that include such IL-2 muteins and methods of treatment using such pharmaceutical compositions. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175709 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654908 | Zarling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Angela Zarling (Richmond, Virginia); Victor H. Engelhard (Crozet, Virginia); Kara L. Cummings (Charlottesville, Virginia); Rebecca C. Obeng (Charlottesville, Virginia) |
| ABSTRACT | Provided are isolated TCRs, TCR-like molecules, and portions thereof that bind to phosphopeptide-HLA-A2 complexes. The isolated TCRs, TCR-like molecules, or portions are optionally soluble TCRs, TCR-like molecules, or portions. Also provided are isolated nucleic acids encoding the disclosed TCRs, TCR-like molecules, or portions; host cells that contain the disclosed TCRs, TCR-like molecules, or portions; pharmaceutical compositions that include the disclosed TCRs, TCR-like molecules, portions, nucleic acids, and/or T cells; kits; and methods of using the same. |
| FILED | Wednesday, April 15, 2015 |
| APPL NO | 15/303677 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 38/19 (20130101) A61K 38/19 (20130101) A61K 38/1774 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) A61K 45/06 (20130101) A61K 47/6425 (20170801) A61K 2039/5158 (20130101) A61K 2039/55533 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/566 (20130101) G01N 33/574 (20130101) G01N 33/56977 (20130101) G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654910 | Spencer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | H. Trent Spencer (Marietta, Georgia); Christopher Doering (Atlanta, Georgia); Philip M. Zakas (Atlanta, Georgia); Eric Gaucher (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to recombinant or chimeric FVIII proteins, variants, and vectors encoding the proteins containing one or more ancestral mutations. In certain embodiments, one or more protein domains comprise amino acid sequences that are derived from ancestrally reconstructed amino acid sequences. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising the proteins or vectors and related methods of inducing blood clotting. |
| FILED | Wednesday, January 27, 2016 |
| APPL NO | 15/547742 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654916 | Bennett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey L. Bennett (Aurora, Colorado); Gregory P. Owens (Aurora, Colorado); Alan S. Verkman (San Francisco, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (Oakland, California); THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Jeffrey L. Bennett (Aurora, Colorado); Gregory P. Owens (Aurora, Colorado); Alan S. Verkman (San Francisco, California) |
| ABSTRACT | The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis. |
| FILED | Monday, April 23, 2012 |
| APPL NO | 14/113061 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2317/21 (20130101) C07K 2317/71 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654919 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/760660 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654925 | Larrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CTS Biopharma LLC (Sunnvale, California) |
| ASSIGNEE(S) | CTS Biopharma LLC (Sunnyvale, California) |
| INVENTOR(S) | James W. Larrick (Sunnyvale, California); John M. Wages (Tupelo, Mississippi); Andrew R. Mendelsohn (Palo Alto, California); Vikram Sharma (San Francisco, California); Bo Yu (Sunnyvale, California) |
| ABSTRACT | The present disclosure provides chimeric, humanized and human monoclonal antibodies (mAbs) and fragments thereof that specifically bind to marinobufagenin (MBG) with high affinity. The anti-MBG mAbs and fragments thereof can be used to treat MBG-associated disorders, including hypertensive disorders and fibrotic disorders, optionally in combination with an additional therapeutic agent. Furthermore, the anti-MBG mAbs and fragments thereof can be used for diagnostic purposes, including to detect MBG in biological samples and to diagnose MBG-associated disorders. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447181 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 16/26 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654943 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | David Ho (Chappaqua, New York); Jian Yu (New York, New York); Xin Yao (New York, New York); Yaoxing Huang (New York, New York) |
| ABSTRACT | Provided are tri-specific fusion antibodies created to target multiple epitopes of the Human Immunodeficiency Virus (HIV). The fusion antibodies provide improved potency and breadth against HIV as compared to monospecific and bispecific antibodies, and additionally provide a high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins. |
| FILED | Thursday, June 02, 2016 |
| APPL NO | 15/579280 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/468 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/76 (20130101) C07K 2317/90 (20130101) C07K 2317/565 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655098 | Ingber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald E. Ingber (Boston, Massachusetts); Hyun Jung Kim (Brookline, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Hyun Jung Kim (Brookline, Massachusetts) |
| ABSTRACT | The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 14/001838 |
| ART UNIT | 1799 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/08 (20130101) C12M 23/38 (20130101) C12M 25/02 (20130101) Original (OR) Class C12M 27/02 (20130101) C12M 29/04 (20130101) C12M 29/06 (20130101) C12M 41/12 (20130101) C12M 41/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655109 | Collins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter L. Collins (Silver Spring, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Cindy Luongo (Bethesda, Maryland) |
| ABSTRACT | Provided herein are novel recombinant respiratory syncytial viruses (RSV) having an attenuated phenotype that contain mutations in the M2-2 open reading frame that interfere with the expression of the M2-2 protein. The M2-2 mutations may be present in combination with mutations at other loci. Using methods described herein, combinations of mutations are provided to achieve desired levels of attenuation. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Also provided are polynucleotide sequences of the described viruses, as well as methods for producing and using the viruses. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 16/061314 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/522 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/18521 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655126 | Rincon et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Vermont and State Agricultural College (Burlington, Vermont); Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGUNE (Derio, Spain) |
| ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont); Asociacion Centro de Investigacion Cooperativa en Biociencias-CIC bioGune (Derio, Spain) |
| INVENTOR(S) | Mercedes Rincon (Burlington, Vermont); Maria Luz Martinez Chantar (Derio, Spain); Juan Anguita (Derio, Spain); Oliver Dienz (Shelburne, Vermont) |
| ABSTRACT | Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to decrease MCJ polypeptide activity in cells, tissues, and/or subjects as a treatment for a drug-induced disease or condition are provided. |
| FILED | Saturday, July 09, 2016 |
| APPL NO | 15/743096 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655130 | Glimcher et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Laurie H. Glimcher (New York, New York); Xi Chen (Malden, Massachusetts) |
| ABSTRACT | Described herein is a previously unknown function of XBP1 in triple-negative breast cancer (TNBC). It is shown that XBP1 is preferentially spliced and activated in TNBC, and that deletion of XBP1 significantly blocks triple negative breast tumor growth. Strikingly, XBP1 is required for the self-renewal of breast tumor initiating cells (TICs). Genome-wide mapping of the XBP1 transcriptional regulatory network identified a fundamental role for XBP1 in regulating the response to hypoxia via the transcription factor hypoxia-inducible factor 1α (HIF1α). Importantly, activation of this pathway appears to carry prognostic implications, as expression of the XBP1-dependent signature is associated with shorter survival times in human TNBC. |
| FILED | Thursday, February 23, 2017 |
| APPL NO | 15/441103 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) Enzymes C12Y 207/11001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57415 (20130101) G01N 2500/04 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655135 | Daniell |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 14/353980 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) A61K 38/51 (20130101) A61K 38/162 (20130101) A61K 38/164 (20130101) A61K 38/2278 (20130101) Peptides C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655172 | Rank et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | David R. Rank (Pacific Grove, California); Jeffrey Wegener (Cupertino, California); Jonas Korlach (Newark, California); Daniel Roitman (Menlo Park, California); Yue Xu (Fremont, California); John Lyle (Redwood Shores, California); Stephen Turner (Kirkland, Washington); Paul Peluso (East Palo Alto, California); Geoff Otto (Brookline, Massachusetts); Ronald L. Cicero (Palo Alto, California) |
| ABSTRACT | Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate. |
| FILED | Friday, June 27, 2014 |
| APPL NO | 14/318324 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0045 (20130101) B01J 2219/0061 (20130101) B01J 2219/00427 (20130101) B01J 2219/00605 (20130101) B01J 2219/00612 (20130101) B01J 2219/00617 (20130101) B01J 2219/00626 (20130101) B01J 2219/00635 (20130101) B01J 2219/00637 (20130101) B01J 2219/00639 (20130101) B01J 2219/00659 (20130101) B01J 2219/00711 (20130101) B01J 2219/00722 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2527/127 (20130101) C12Q 2565/629 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655173 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Joshua Asher Weinstein (Cambridge, Massachusetts); Aviv Regev (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to molecular microscopy or volumetric imaging by proximal unique molecular identifiers (“UID”) reaction (“VIPUR”) microscopy methods to record the cellular co-localization and/or spatial distributions of arbitrary nucleic acid sequences, or other biomolecules tagged with nucleic sequences. The method involves one or both of two DNA sequence-components such as an α-UID, which may identify the targeted sequences-of-interest themselves and/or spatial beacons relative to which their distances are measured, and a- β-UID, which labels α-UID association events. |
| FILED | Friday, October 17, 2014 |
| APPL NO | 15/030154 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6846 (20130101) C12Q 1/6846 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2533/107 (20130101) C12Q 2543/101 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655182 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Barbara Murphy (Pelham Manor, New York); Weijia Zhang (Cresskill, New Jersey) |
| ABSTRACT | Disclosed herein is a method for diagnosing a renal allograft recipient's risk for developing fibrosis of the allograft and allograft loss. The method includes determining the expression levels of certain microRNAs, which have been determined to be predictive of an allograft recipient's risk. Also disclosed herein is a method of treating a renal allograft recipient to inhibit fibrosis of the allograft and allograft loss, as well as kits for use in the methods disclosed herein. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/424014 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/343 (20130101) A61K 31/436 (20130101) A61K 31/573 (20130101) A61K 31/4412 (20130101) A61K 31/5377 (20130101) A61K 38/13 (20130101) A61K 38/18 (20130101) A61K 38/1774 (20130101) A61K 38/1875 (20130101) A61K 38/2221 (20130101) Peptides C07K 14/70521 (20130101) C07K 2319/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) G01N 2800/245 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655183 | Gerner et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Eugene Gerner (Tucson, Arizona); Patricia Thompson (Tucson, Arizona); Tracy Brooks (Oxford, Mississippi); Jenaro Garcia-Huidobro (Tucson, Arizona) |
| ABSTRACT | The present invention provides methods and kits a) for preventing and/or treating cancer (e.g., colorectal cancer, neuroblastoma) that is linked, in part, to high levels of ODC activity and increased cellular polyamine content, b) for predicting cancer patient survival, especially cancer patient's whose cancer is linked, in part, to high levels of ODC activity and increased cellular polyamine contents, and c) for selecting the corresponding treatment options for such patients based on the allelic nucleotide sequence or SNP at positions +263 and/or +316 of the ODC1 gene as well as cancer treatment methods, in each case, which include the determination of the ODC1 genotype at the +263 and/or +316 positions, as a means to guide treatment selection. |
| FILED | Wednesday, June 18, 2014 |
| APPL NO | 15/319857 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/198 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655184 | Adai et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTERPACE DIAGNOSTICS, LLC (Parsippany, New Jersey) |
| ASSIGNEE(S) | INTERPACE DIAGNOSTICS, LLC (Parsippany, New Jersey) |
| INVENTOR(S) | Alex Adai (Austin, Texas); Anna Szafranska-Schwarzbach (Austin, Texas); Bernard Andruss (Austin, Texas); Stephan Albrecht Hahn (Bochum, Germany) |
| ABSTRACT | Provided are methods and compositions for identifying a miRNA profile for a particular condition, such as pancreatic disease, and using the profile in assessing the condition of a patient. |
| FILED | Wednesday, April 19, 2017 |
| APPL NO | 15/491399 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655189 | Alland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | David Alland (Bernardsville, New Jersey); Soumitesh Chakravorty (Somerset, New Jersey) |
| ABSTRACT | This invention relates to nucleic acids, reagents and methods for detecting Rifampicin-resistant Mycobacterium tuberculosis in a sample from a subject. In one aspect, the invention provides methods of detecting Rifampicin resistant M. tuberculosis in a sample comprising (a) amplifying a nucleic acid containing the rifampicin resistance determining region (RRDR) of the rpoB gene in a sample to provide an amplified nucleic acid; (b) probing the amplified nucleic acid with at least three molecular beacon probes for an RRDR mutant target; (c) conducting melting temperature (Tm) analysis to determine a Tm value for each probe; and (d) comparing the Tm value for each probe with a Tm value for a wild-type RRDR region, wherein a Tm value for at least one of the molecular beacon probes that is greater than the Tm value for the wild-type RRDR indicates the presence of rifampicin resistant M. tuberculosis in the sample. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650123 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656117 | Mayer et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Michael Mayer (Ann Arbor, Michigan); Erik Yusko (Seattle, Washington) |
| ABSTRACT | Physical parameters of macromolecules are determined by measuring electrical current I over time for translocation events as the macromolecules in solution move between two liquid compartments that are separated by and fluidically coupled through a synthetic nanopore. Values of charge, volume, shape, rotational diffusion coefficient, and dipole moment are derived from the measurements. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436591 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656229 | Meade et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Thomas J. Meade (Wilmette, Illinois); Hsiang-Hua Hung (Chicago, Illinois) |
| ABSTRACT | Provided herein is technology relating to magnetic resonance imaging contrast agents and particularly, but not exclusively, to methods and systems for visualizing one or more magnetic resonance imaging contrast agent. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/479821 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/055 (20130101) A61B 5/7267 (20130101) A61B 6/037 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/481 (20130101) G01R 33/5601 (20130101) Original (OR) Class G01R 33/5616 (20130101) G01R 33/5617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656403 | Shroff et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hari Shroff (Washington, District of Columbia); Andrew York (Bethesda, Maryland) |
| ABSTRACT | A structured illumination microscopy (SIM) system for generating single focal point patterns of a sample is disclosed. The SIM system performs a focusing, scaling and summing operation on each single focal point that completely scan the sample to produce a high resolution composite image. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/387842 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2021/6478 (20130101) G01N 2201/0633 (20130101) Optical Elements, Systems, or Apparatus G02B 21/004 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0072 (20130101) Original (OR) Class G02B 21/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656885 | Hamlen |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Kevin W. Hamlen (Richardson, Texas) |
| ABSTRACT | The present disclosure is directed to a method of creating an object flow integrity (OFI) library module, capable of redirecting an object-like programmatic call, by initiating a multi-pass, recursive process to analyze a module's interfaces, function parameters, and data types. In another aspect, a method is disclosed to modify the binary code of an untrusted module to enable its usage of the OFI library module. In another aspect, during runtime operations of an untrusted module, the OFI library module can receive an object from a caller module, substitute a proxy object, stored in a secure location, and continue the programmatic call using the proxy object. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/173358 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/1222 (20130101) Original (OR) Class G06F 16/1734 (20190101) G06F 21/6209 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 15/4095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657634 | Green |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Jason Green (Bloomington, Indiana) |
| ABSTRACT | Methods for processing an image comprising assigning values to a plurality of pixels of an image, placing the values of the plurality of pixels in an array, determining a method to reference the array values with indices, determining a method to rank or sort the values, sorting the array of values and storing the indices that would sort the array, sorting the array of indices and storing the indices that would sort the array in an array of values, recursively applying these methods, changing methods configurations and/or reusing them during processing, and altering an array based on a sorted array's values and/or indices are disclosed. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/781239 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4652 (20130101) Image Data Processing or Generation, in General G06T 1/0042 (20130101) G06T 7/0002 (20130101) Original (OR) Class G06T 2207/10024 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 5/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657645 | Parsey et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Ramin Parsey (Mountain Lakes, New Jersey); Arthur Mikhno (New City, New York) |
| ABSTRACT | The subject matter disclosed herein relates to methods for diagnosing a neurological disorder in a subject. In certain aspects, the methods described herein involve determining one or more critical areas in the brain from molecular Magnetic Resonance Imaging (MRI) data where two groups differ and measuring MRI signal within determined critical areas in a new subject in order to assign risk or diagnosis. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869851 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/4088 (20130101) A61B 5/7275 (20130101) A61B 6/037 (20130101) A61B 6/56 (20130101) A61B 6/501 (20130101) A61B 6/563 (20130101) A61B 6/5247 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/10 (20130101) G01R 33/0023 (20130101) G01R 33/481 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/6267 (20130101) G06K 2009/4666 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0014 (20130101) Original (OR) Class G06T 7/0016 (20130101) G06T 7/41 (20170101) G06T 2200/04 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/20021 (20130101) G06T 2207/20076 (20130101) G06T 2207/20128 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658081 | Traughber et al. |
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| FUNDED BY |
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| APPLICANT(S) | ELOQUENCE COMMUNICATIONS, INC. (Seattle, Washington) |
| ASSIGNEE(S) | Eloquence Communications, Inc. (Seattle, Washington) |
| INVENTOR(S) | Bryan James Traughber (Shaker Heights, Ohio); Lance S. Patak (Seattle, Washington) |
| ABSTRACT | A provider device for advanced patient communication and methods for making and using same. According to one embodiment, a provider device comprises a receiver for receiving one or more messages from a central processing server, each of the one or more messages reflecting a patient request, an urgency level associated with the patient request, one or more action items associated with the patient request, and a lapse in time since receiving the patient request. The provider device also includes a display for displaying, based on the one or more messages, a patient listing including status information corresponding to one or more patients. |
| FILED | Wednesday, May 18, 2016 |
| APPL NO | 15/158070 |
| ART UNIT | 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0022 (20130101) A61B 5/7282 (20130101) A61B 5/7475 (20130101) A61B 2560/045 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 5/222 (20130101) G08B 21/0211 (20130101) G08B 21/0277 (20130101) G08B 25/10 (20130101) G08B 25/016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 15/00 (20180101) G16H 40/20 (20180101) G16H 40/63 (20180101) Original (OR) Class Telephonic Communication H04M 1/72527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658530 | Goldan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Amirhossein Goldan (Stony Brook, New York); Wei Zhao (East Setauket, New York) |
| ABSTRACT | Provided is a field shaping multi-well detector and method of fabrication thereof. The detector is configured by depositing a pixel electrode on a substrate, depositing a first dielectric layer, depositing a first conductive grid electrode layer on the first dielectric layer, depositing a second dielectric layer on the first conductive grid electrode layer, depositing a second conductive grid electrode layer on the second dielectric layer, depositing a third dielectric layer on the second conductive grid electrode layer, depositing an etch mask on the third dielectric layer. Two pillars are formed by etching the third dielectric layer, the second conductive grid electrode layer, the second dielectric layer, the first conductive grid electrode layer, and the first dielectric layer. A well between the two pillars is formed by etching to the pixel electrode, without etching the pixel electrode, and the well is filled with a-Se. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 16/068563 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1461 (20130101) H01L 27/1463 (20130101) H01L 27/14612 (20130101) H01L 27/14632 (20130101) H01L 27/14636 (20130101) H01L 27/14643 (20130101) H01L 27/14659 (20130101) H01L 27/14692 (20130101) H01L 27/14696 (20130101) H01L 31/105 (20130101) H01L 31/107 (20130101) H01L 31/0272 (20130101) Original (OR) Class H01L 31/0376 (20130101) H01L 31/02161 (20130101) H01L 31/022408 (20130101) H01L 31/035209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659328 | Sundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vinaitheerthan Sundaram (West Lafayette, Indiana); Patrick Eugster (West Lafayette, Indiana); Xiangyu Zhang (West Lafayette, Indiana) |
| ABSTRACT | A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. The stored packet-identification value is then increased and the process repeats. To receive data, an expected identification value is stored in association with the identifier. A packet and a packet-identification value are received from the network device. The identifier and an indication of receipt are stored. If the received value does not match the expected value for the identifier, the received value is stored. If the values match, the stored packet-identification value and identifier are recorded. If the received value exceeds the expected value, the stored packet-identification value, the identifier and the received identifier are recorded. Subsequently, the stored expected value is increased. The process repeats. Network devices and systems are described. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367383 |
| ART UNIT | 2466 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3636 (20130101) G06F 16/1744 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 69/04 (20130101) H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10653319 | Vakoc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Benjamin Vakoc (Arlington, Massachusetts); Meena Siddiqui (Boston, Massachusetts); Serhat Tozburun (Malden, Massachusetts) |
| ABSTRACT | An apparatus can be provided which can include a laser arrangement which can be configured to provide a laser radiation, and can include an optical cavity. The optical cavity can include a dispersive optical first arrangement which can be configured to receive and disperse at least one first electro-magnetic radiation so as to provide at least one second electro-magnetic radiation. Such cavity can also include an active optical modulator second arrangement which can be configured to receive and modulate the at least one second radiation so as to provide at least one third electro-magnetic radiation. The optical cavity can further include a dispersive optical third arrangement which can be configured to receive and disperse at least one third electro-magnetic radiation so as to provide at least one fourth electro-magnetic radiation. For example, actions by the first, second and third arrangements can cause a spectral filtering of the fourth electro-magnetic radiation(s) relative to the first electro-magnetic radiation(s). The laser radiation can be associated with the fourth radiation(s), and a wavelength of the laser radiation can be controlled by the spectral filtering caused by the actions by the first, second and third arrangements. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/051014 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/0075 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) G01B 9/02005 (20130101) G01B 9/02007 (20130101) G01B 9/02008 (20130101) G01B 9/02014 (20130101) G01B 9/02044 (20130101) G01B 9/02091 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/0811 (20130101) H01S 3/1062 (20130101) H01S 3/1109 (20130101) H01S 3/06725 (20130101) H01S 3/06791 (20130101) H01S 3/08004 (20130101) H01S 5/50 (20130101) H01S 2301/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653330 | Angle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PARADROMICS, INC. (Austin, Texas) |
| ASSIGNEE(S) | PARADROMICS, INC. (Austin, Texas) |
| INVENTOR(S) | Matthew Angle (Austin, Texas); Edmund Huber (San Francisco, California); Robert Edgington (Austin, Texas) |
| ABSTRACT | Systems and methods for processing neural signals are provided. A neural data analysis system may comprise a feature extraction module configured to extract a plurality of features from neural signal waveforms obtained by an implanted neural interface probe with a plurality of channels or electrodes, and transmit the extracted features as a plurality of discrete outputs. The neural data analysis system may also comprise a feature-event coalescence module configured to receive the plurality of discrete outputs from the feature extraction module, and construct a model-based inference of bioelectric activity based on feature event statistics, prior knowledge of bioelectric signals, and/or a behavioral model of the feature extraction module. The neural data analysis system may further comprise an approximator module configured to receive a plurality of coalesced events from the feature-event coalescence module, and apply a series of transformations to the coalesced event data to generate a higher entropy neural code. |
| FILED | Wednesday, February 13, 2019 |
| APPL NO | 16/275205 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04 (20130101) A61B 5/048 (20130101) A61B 5/0478 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4064 (20130101) A61B 5/6868 (20130101) A61B 5/7239 (20130101) A61B 5/7242 (20130101) A61B 5/7246 (20130101) A61B 5/7253 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10653342 — Soft, wearable microfluidic systems capable of capture, storage, and sensing of biofluids
| US 10653342 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Jungil Choi (Chicago, Illinois); Sungbong Kim (Champaign, Illinois) |
| ABSTRACT | The invention provides systems for handling biofluids including the transport, capture, collection, storage, sensing, and/or evaluation of biofluids released by tissue. Systems of some aspects provide a versatile platform for characterization of a broad range of physical and/or chemical biofluid attributes in real time and over clinically relevant timeframes. Systems of some aspects provide for collection and/or analysis of biofluids from conformal, watertight tissue interfaces over time intervals allowing for quantitative temporal and/or volumetric characterization of biofluid release, such as release rates and release volumes. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625087 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/6833 (20130101) A61B 5/14517 (20130101) Original (OR) Class A61B 2560/0214 (20130101) A61B 2560/0462 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2300/0803 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653362 | Chon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts) |
| ASSIGNEE(S) | Wavefront Research Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | Ki H. Chon (Worcester, Massachusetts); Jo Woon Chong (Worcester, Massachusetts); Duy Dao (Malden, Massachusetts); Hamed Salehizadeh (Worcester, Massachusetts) |
| ABSTRACT | A pulse oximeter embedded with a motion and noise artifact (MNA) detection algorithm based on extraction of time-varying spectral features that are unique to the clean and corrupted components. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/010345 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/725 (20130101) A61B 5/1455 (20130101) A61B 5/02416 (20130101) A61B 5/7207 (20130101) Original (OR) Class A61B 5/7257 (20130101) A61B 5/7267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653422 | Rago et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARSENAL MEDICAL, INC. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Arsenal Medical, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Adam Rago (Falmouth, Massachusetts); John Marini (Milford, Connecticut); Gregory T. Zugates (Chelmsford, Massachusetts); Marc Helmick (Brighton, Massachusetts); Upma Sharma (Somerville, Massachusetts) |
| ABSTRACT | Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/729993 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12 (20130101) Original (OR) Class A61B 2017/12004 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0036 (20130101) A61L 24/046 (20130101) A61L 24/046 (20130101) A61L 2400/04 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 13/003 (20130101) A61M 2205/3341 (20130101) A61M 2205/3344 (20130101) A61M 2210/12 (20130101) A61M 2210/1021 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653516 | Eastwood |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gov of the United States, as rep. by US Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Matthew A Eastwood (Travis AFB, California) |
| ABSTRACT | An artificial muscle including an internal electromechanically charged rod extending beyond two attach points. A plurality of mesh cylinders having a mesh cylinder top and a mesh cylinder bottom surrounding the charged rod. A fiber surrounding the mesh cylinders and mechanically attached to the mesh cylinders at an attachment spacing and wherein an electromagnetic source activates the artificial muscle through at least one microprocessor. The artificial muscle fiber may be nylon and the attach points may be titanium. The artificial muscle fiber may be coated with nylon. The artificial muscle fiber may contain a viscous fluid. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043672 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class A61F 2/68 (20130101) A61F 2002/705 (20130101) A61F 2002/0894 (20130101) A61F 2002/6863 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653757 | Yeaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael R. Yeaman (Redondo Beach, California); John E. Edwards, Jr. (Palos Verdes Estates, California); Scott G. Filler (Rancho Palos Verdes, California); Ashraf S. Ibrahim (Irvine, California); Yue Fu (Carson, California); John P. Hennessey, Jr. (Lower Gwynedd, Pennsylvania) |
| ASSIGNEE(S) | NovaDigm Therapeutics, Inc. (Grand Forks, North Dakota); Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (Torrance, California) |
| INVENTOR(S) | Michael R. Yeaman (Redondo Beach, California); John E. Edwards, Jr. (Palos Verdes Estates, California); Scott G. Filler (Rancho Palos Verdes, California); Ashraf S. Ibrahim (Irvine, California); Yue Fu (Carson, California); John P. Hennessey, Jr. (Lower Gwynedd, Pennsylvania) |
| ABSTRACT | The invention features a method of vaccinating a mammal against Staphylococcus aureus which includes the steps of: a) identifying a mammal at risk for the development of a Staphylococcus aureus skin or soft tissue infection; and b) administering to said mammal an immunogenic amount of a vaccine that includes a polypeptide including an isolated agglutinin-like sequence (Als) 3 protein (Als3p), or an immunogenic fragment thereof, in a pharmaceutically acceptable medium. |
| FILED | Friday, July 20, 2012 |
| APPL NO | 14/234269 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/58 (20130101) A61K 2039/55505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653768 | Mutzke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CureVac Real Estate GmbH (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac Real Estate GmbH (Tübingen, Germany) |
| INVENTOR(S) | Thorsten Mutzke (Reutlingen, Germany); Markus Kreuz (Kohlberg, Germany); Stefanie Sewing (Tübingen, Germany); Fabian Johannes Eber (Stuttgart, Germany); Wenke Wagner (Reutlingen, Germany); Michael Sonntag (Tübingen, Germany); Michael Wiggenhorn (München, Germany); Katharina Kolland (Augsburg, Germany) |
| ABSTRACT | The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/566010 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) A61K 9/5192 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 47/6455 (20170801) A61K 2039/55555 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653786 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Xiaoqin Wang (Winchester, Massachusetts); Vijay John (New Orleans, Louisiana); Noshir Pesika (New Orleans, Louisiana); Rubo Zheng (New Orleans, Louisiana) |
| ABSTRACT | Provided herein relates to compositions and methods for lubrication of a surface. The surface amenable to the compositions and methods described herein can be a non-biological surface, a biological surface, or a combination thereof. In some embodiments, the composition comprising a phospholipid-coated silk microsphere can be used for lubrication of a surface. In some embodiments, the composition comprising a phospholipid-coated silk microsphere can be used for joint lubrication, e.g., for treatment of joint disorders such as arthritis. |
| FILED | Thursday, April 25, 2013 |
| APPL NO | 14/390351 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1617 (20130101) A61K 45/06 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/28 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/3645 (20130101) A61L 2300/622 (20130101) A61L 2400/10 (20130101) A61L 2430/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653797 | Ruoslahti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Erkki Ruoslahti (La Jolla, California); Aman Mann (La Jolla, California); Pablo Scodeller (La Jolla, California); Sazid Hussain (La Jolla, California) |
| ABSTRACT | Disclosed are methods and compositions for selectively targeting sites of traumatic brain injury (TBI). A brain injury-specific 4-amino acid peptide (sequence CAQK), identified by in vivo phage display screening in mice with acute brain injury, shows selective binding to mouse and human brain injury lesions, and when systemically injected, specifically homes to sites of injury in penetrating and non-penetrating (controlled cortical impact) brain injury models. Also disclosed are methods and compositions for delivering therapeutic compounds to such sites. CAQK-coated nanoparticles containing silencing oligonucleotides provide an alternative to local delivery of therapeutics, which is invasive and can add complications to the injury. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/756947 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5115 (20130101) A61K 47/62 (20170801) A61K 47/6425 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 48/005 (20130101) A61K 48/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Peptides C07K 5/1013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653803 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Liangfang Zhang (San Diego, California) |
| ABSTRACT | Living cells, such as red blood cells (RBCs) modified with functional micromotors with the aid of ultrasound propulsion and magnetic guidance. Iron oxide nanoparticles are loaded into the RBCs, where their asymmetric distribution within the cells results in a net magnetization, thus enabling magnetic alignment and guidance under acoustic propulsion. The RBC motors display efficient guided and prolonged propulsion in various biological fluids, including undiluted whole blood. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/356977 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/5094 (20130101) A61K 9/5115 (20130101) A61K 35/18 (20130101) A61K 41/00 (20130101) A61K 47/6901 (20170801) A61K 49/0067 (20130101) A61K 49/0097 (20130101) Original (OR) Class A61K 2035/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653813 | Stewart |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Russell J. Stewart (Salt Lake City, Utah) |
| ABSTRACT | Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 15/833157 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/06 (20130101) A61L 24/10 (20130101) A61L 24/0015 (20130101) A61L 24/043 (20130101) A61L 24/043 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/54 (20130101) A61L 2300/62 (20130101) A61L 2430/16 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 8/06 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653817 | Francis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMBODY INC. (Norfolk, Virginia) |
| ASSIGNEE(S) | EMBODY INC. (Norfolk, Virginia) |
| INVENTOR(S) | Michael P. Francis (Norfolk, Virginia); Yas Maghdouri-White (Norfolk, Virginia); Hilary Wriggers (Norfolk, Virginia); Nardos Sori (Norfolk, Virginia); Stella Petrova (Norfolk, Virginia); Seth Polk (Norfolk, Virginia); Nicholas Thayer (Norfolk, Virginia) |
| ABSTRACT | Compositions and blends of biopolymers and bio-acceptable polymers are described, along with the use of benign solvent systems to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222350 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/3662 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 27/3834 (20130101) A61L 2430/10 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 89/06 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) D01D 5/0038 (20130101) D01D 5/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653880 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eastern Virginia Medical School (Norfolk, Virginia); Old Dominion University Research Foundation (Norfolk, Virginia) |
| ASSIGNEE(S) | Eastern Virginia Medical School (Norfolk, Virginia); Old Dominion University Research Foundation (Norfolk, Virginia) |
| INVENTOR(S) | Stephen J. Beebe (Norfolk, Virginia); Karl H. Schoenbach (Norfolk, Virginia) |
| ABSTRACT | A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nsPEF's”). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell. In a preferred embodiment, the present invention is directed to a method of enhancing gene expression in a cell comprising the application of nanosecond pulse electric fields to said cell. An apparatus for generating long and short pulses according to the present invention is also provided. The apparatus includes a pulse generator capable of producing a first pulse having a long duration and low voltage amplitude and a second pulse having a short duration and high voltage amplitude. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 15/654625 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) A61N 1/0412 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654086 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ryan Bruce Anderson (Great Mills, Maryland); Bradley Yost (Lexington Park, Maryland); Matthew Stone (Lexington Park, Maryland); Tiffany Lei (La Plata, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Bruce Anderson (Great Mills, Maryland); Bradley Yost (Lexington Park, Maryland); Matthew Stone (Lexington Park, Maryland); Tiffany Lei (La Plata, Maryland) |
| ABSTRACT | A tensioning device for a sheet of material that includes a first ring with protrusions, a second ring, and a shaft. The first ring and the second ring are positioned such that the sheet of material can be clamped between the first ring and the second ring. The shaft has an outer surface, the outer surface includes a spiral race such that the protrusions of the first ring follow the spiral race, allowing the first ring and the second ring to displace linearly causing the sheet of material to be stretched. The spiral race includes a plurality of notches that correspond to the protrusions. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949549 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 11/02 (20130101) Original (OR) Class B21D 25/02 (20130101) B21D 25/04 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 55/165 (20130101) Gearing F16H 25/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654168 | Khripin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Alex Khripin (Waltham, Massachusetts); Alfred Anthony Rizzi (Cambridge, Massachusetts) |
| ABSTRACT | A control system may receive a first plurality of measurements indicative of respective joint angles corresponding to a plurality of sensors connected to a robot. The robot may include a body and a plurality of jointed limbs connected to the body associated with respective properties. The control system may also receive a body orientation measurement indicative of an orientation of the body of the robot. The control system may further determine a relationship between the first plurality of measurements and the body orientation measurement based on the properties associated with the jointed limbs of the robot. Additionally, the control system may estimate an aggregate orientation of the robot based on the first plurality of measurements, the body orientation measurement, and the determined relationship. Further, the control system may provide instructions to control at least one jointed limb of the robot based on the estimated aggregate orientation of the robot. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/137796 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1664 (20130101) B25J 9/1694 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 57/032 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/39082 (20130101) G05B 2219/39215 (20130101) G05B 2219/39325 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 2201/0217 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/09 (20130101) Y10S 901/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654588 | Bajekal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Sanjay Bajekal (Simsbury, Connecticut); Brian Dean Bouquillon (Fort Worth, Texas); Cagatay Tokgoz (South Windsor, Connecticut) |
| ABSTRACT | A method of data collection from a rotor system of an aircraft includes positioning a plurality of sensors at a plurality of locations of a rotating portion of the rotor system. One or more antennae are located at one or more rotationally fixed locations of the aircraft. Rotor system data is collected via the sensors and is wirelessly transmitted from the sensors to the antennae and is transferred from the antennae to a gateway where it is normalized and synchronized. In another embodiment, a data collection system for a rotor includes a plurality of sensors located at rotating locations of the rotor, the sensors configured to collect and wirelessly transmit rotor data. Antennae are located at a fixed location of the aircraft. The antennae are configured to send and receive data from the sensors. A gateway is connected to the antennae to normalize and synchronize the rotor data. |
| FILED | Thursday, March 26, 2015 |
| APPL NO | 15/301104 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/06 (20130101) B64C 27/008 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/0005 (20130101) Original (OR) Class B64D 2045/0085 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0841 (20130101) Selecting H04Q 9/00 (20130101) H04Q 2209/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654595 | Reed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Phillippe L. Reed (Charleston, South Carolina) |
| ABSTRACT | A vehicle, such as a satellite or other spacecraft, includes an electrodynamic tether connected thereto. A processor, contained within the vehicle and connected to the electrodynamic tether, is configured to cause a current to be directed to the electrodynamic tether to cause a change in motion of the vehicle. Sensors, such as an attitude sensor, a position sensor, a magnetometer, and an ionosphere sensor, are contained within the vehicle and are connected to the processor. The processor is configured to direct current to the electrodynamic tether based upon input received from the sensors to maintain the vehicle within a specified orbit, such as a highly-inclined eccentric orbit over the polar or other high-latitude region, or to change the vehicle's orbit. The processor may be configured in a closed-loop configuration to account for measured errors by the sensors position, attitude, ionospheric charge density, and/or the Earth's magnetic field. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 15/682761 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/32 (20130101) B64G 1/36 (20130101) B64G 1/40 (20130101) B64G 1/42 (20130101) B64G 1/242 (20130101) B64G 1/648 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654919 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York); Simone Mader (Woodside, New York); Lior Brimberg (Bayside, New York); Peter Gregersen (Larchmont, New York) |
| ABSTRACT | Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/760660 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/38 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655185 | Chakrabarti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); University of Center Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ratna Chakrabarti (Winter Springs, Florida); Richard Ottman (Orlando, Florida); Domenico Coppola (Tampa, Florida); Nupam Mahajan (Tampa, Florida) |
| ABSTRACT | A biomarker is disclosed that can distinguish aggressive epithelial tumors in a tissue biopsy from, for example, normal, hyperplastic, and benign neoplastic tumors. The biomarker can also identify epithelial tumors that have become resistant to hormone therapy. Therefore, methods are disclosed for providing diagnosis and prognosis of a subject having, or suspected of having, an epithelial tumor, such as a prostate tumor. |
| FILED | Tuesday, November 10, 2015 |
| APPL NO | 15/525787 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655350 | Hartmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Dale R Hartmann (Front Royal, Virginia); Tara C Brady (Kearneysville, West Virginia); Michael D. Bluhm (Shawnee, Kansas) |
| ABSTRACT | The disclosed invention is a housing apparatus comprised of foundation boxes, foundation box lids, in situ ballast material placed within the foundation boxes, floor panels, wall panels, binding strips, stackable trussed roof segments, roof gables, and load transferring batten strips. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/815652 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/3205 (20130101) E04B 1/3483 (20130101) E04B 1/34321 (20130101) E04B 1/34336 (20130101) E04B 2/84 (20130101) E04B 7/022 (20130101) E04B 2001/2644 (20130101) E04B 2001/3241 (20130101) E04B 2001/3252 (20130101) E04B 2001/34389 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) Original (OR) Class E04H 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655487 | Sonokawa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Masayoshi Sonokawa (West Hartford, Connecticut); Rachel A. McGrath (Hartford, Connecticut) |
| ABSTRACT | An annular stator seal support extends radially between a radial inner support side and a radial outer support side. A secondary seal includes a first radially extending secondary seal sidewall surface, a second radially extending secondary seal sidewall surface and a third radially extending secondary seal sidewall surface. An annular stator sleeve support includes a channel radially distal the radial inner support side, the channel includes a first radially extending channel sidewall and a second radially extending channel sidewall located axially forward of the first radially extending channel sidewall, and a third radially extending channel sidewall located axially behind the first radially extending channel sidewall. The first radially extending seal sidewall surface contacts the first radially extending channel sidewall, and the second radially extending channel sidewall is axially spaced from the second radially extending secondary seal sidewall surface. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897748 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) F05D 2240/58 (20130101) Pistons; Cylinders; Sealings F16J 15/002 (20130101) F16J 15/164 (20130101) F16J 15/344 (20130101) F16J 15/441 (20130101) F16J 15/3452 (20130101) F16J 15/3464 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655496 | Mongillo, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Adam P. Generale (Dobbs Ferry, New York) |
| ABSTRACT | Component for gas turbine engines are provided. The components include a platform, the platform defining a platform cavity on a first side, an airfoil extending from a second side of the platform, wherein the airfoil comprises at least one airfoil cavity located within the airfoil, the at least one airfoil cavity fluidly connected to the platform cavity through an airfoil cavity inlet, and a platform flow turning element positioned on the first side of the platform, the platform flow turning element having a turning portion and a tapering portion, wherein the turning portion directs incoming air to turn from the platform cavity into the airfoil cavity and the tapering portion extends through the airfoil cavity inlet and into the airfoil cavity. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/852198 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/141 (20130101) F01D 5/147 (20130101) F01D 5/187 (20130101) F01D 5/188 (20130101) F01D 9/02 (20130101) F01D 9/042 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/80 (20130101) F05D 2240/81 (20130101) F05D 2260/20 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655663 | Jacobs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Harry Robert Jacobs (Fort Worth, Texas); Brian Beavers (Fort Worth, Texas); Derek Michael Newman (Fort Worth, Texas) |
| ABSTRACT | In an embodiment, a system includes a first structure comprising a first aperture and a second structure comprising a second aperture. The system also includes a first pin configured to be inserted into the first aperture of the first structure and a retaining device configured to be coupled to the first pin. The system further includes a second pin configured to be inserted into the second aperture of the second structure and coupled to the first pin. The first pin includes a first shoulder and a second shoulder, the first shoulder having a different diameter than the second shoulder. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/720481 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/12 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/02 (20130101) F16B 5/08 (20130101) F16B 13/0825 (20130101) Original (OR) Class F16B 19/00 (20130101) F16B 19/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655870 | Lowenstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AIL RESEARCH INC. (Princeton Junction, New Jersey) |
| ASSIGNEE(S) | AIL RESEARCH, INC. (Hopewell, New Jersey) |
| INVENTOR(S) | Andrew Lowenstein (Princeton Junction, New Jersey) |
| ABSTRACT | A device for cooling and dehumidifying a first stream of air includes a first heat exchanger that cools the first stream of air from a first temperature to a lower second temperature, an absorber, a regenerator and one or more pumps and conduits. The device operates under conditions where liquid desiccant removes moisture from the first stream of air in the absorber and the second temperature of the first stream of air that leaves the first heat exchanger is lower than the temperature of the liquid desiccant supplied to the absorber. |
| FILED | Friday, October 24, 2014 |
| APPL NO | 15/504528 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 3/1429 (20130101) F24F 2003/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656016 | Burghoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Burghoff (Cambridge, Massachusetts); Yang Yang (Cambridge, Massachusetts); Qing Hu (Wellesley, Massachusetts) |
| ABSTRACT | According to one aspect, a multi-heterodyne system is disclosed, which comprises a first laser source for generating multi-mode radiation having a frequency spectrum characterized by a first plurality of phase coherent frequencies, and a second laser source for generating multi-mode radiation having a frequency spectrum characterized by a second plurality of phase coherent frequencies. The system further comprises at least one detector for detecting a combination of the multi-mode radiation generated by the first and second laser sources so as to provide a multi-heterodyne signal having a frequency spectrum characterized by a plurality of beat frequencies, each beat frequency corresponding to a pairwise difference in the first and second plurality of phase coherent frequencies. The system further comprises an analyzer for receiving said multi-heterodyne signal and configured to employ a predictive model of the multi-heterodyne signal to provide estimates of any of phase error and timing error associated with the beat frequencies. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148794 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/28 (20130101) Original (OR) Class G01J 3/42 (20130101) G01J 3/108 (20130101) G01J 3/2803 (20130101) G01J 3/4531 (20130101) G01J 9/04 (20130101) G01J 2003/102 (20130101) G01J 2003/284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656149 | Chou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (PRINCETON, New Jersey) |
| INVENTOR(S) | Stephen Y. Chou (Princeton, New Jersey); Liang-Cheng Zhou (Princeton, New Jersey) |
| ABSTRACT | This disclosure provides, among other things, a method of sample analysis, that comprises: (a) binding target analytes to capture agents that are attached to a surface of a plate, wherein the plate comprises (i) a sensing amplification layer comprises nanostructures that enhance signals and (ii) the capture agents are attached to said sensing amplification layer; (b) reading the plate with a reading device to produce an image of signals that represent individual binding events; and (c) identifying and counting individual binding events in an area of the image, thereby providing an estimate of the amount of one or more analytes in the sample. A system for performing the method is also provided. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/775638 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54386 (20130101) Original (OR) Class G01N 33/57473 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656171 | Pleiman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Brock J. Pleiman (Mason, Ohio); Angela R. Scribben (Springfield, Ohio); Frank C. Semmelmayer (Dayton, Ohio); Kevin L. King (Springfield, Ohio) |
| ABSTRACT | An air speed probe with a cylindrical probe body having a length, and a frusto-conical tip at an end of the cylindrical probe body. A center bore with a first diameter and first depth is formed in a center of the tip and coaxially disposed along a portion of the length of the cylindrical probe body. Radial bores with second diameters and second depths are formed in a sidewall of the tip, where the first diameter is wider than the second diameter, and the first depth is shallower than the second depth. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209335 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/34 (20130101) G01F 1/206 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/16 (20130101) Original (OR) Class G01P 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656282 | Irish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Andrew Irish (Mountain View, California); Jason Isaacs (Camarillo, California); Upamanyu Madhow (Santa Barbara, California) |
| ABSTRACT | A method of determining location of a user device includes receiving global navigation satellite system (GNSS) fix data that represents GNSS calculated position of the user device. The method further includes receiving signal strength data associated with each satellite communicating with the user device, and receiving map information regarding environment surrounding the user device. The received GNSS fix data and signal strength data is provided to a non-linear filter, wherein the non-linear filter fuses the GNSS fix data and signal strength data to generate an updated position estimate of the user device. In addition, the non-linear filter utilizes probabilistic shadow matching estimates that represent a likelihood of received signal strength data as a function of hypothesized user device locations within the environment described by the received map information. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/211808 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/22 (20130101) Original (OR) Class G01S 19/42 (20130101) G01S 19/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10656354 — Apparatus providing simplified alignment of optical fiber in photonic integrated circuits
| US 10656354 | Sandhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Gurtej Sandhu (Boise, Idaho); Roy Meade (Boise, Idaho); Lei Bi (Boise, Idaho); John Smythe (Boise, Idaho) |
| ABSTRACT | A structure for optically aligning an optical fiber to a photonic device and method of fabrication of same. The structure optically aligns an optical fiber to the photonic device using a lens between the two which is moveable by actuator heads. The lens is moveable by respective motive sources associated with the actuator heads. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/936033 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) G02B 6/32 (20130101) G02B 6/4204 (20130101) G02B 6/4206 (20130101) G02B 6/4225 (20130101) G02B 6/4226 (20130101) Original (OR) Class G02B 6/4227 (20130101) G02B 6/4239 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/42 (20150115) Y10T 29/49 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656497 | Lentz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joshua Lentz (Niceville, Florida) |
| ABSTRACT | A scene projector includes a first cycloidal diffractive waveplate (CDW) having first pixels that are switchable such that light from a zero order passes through along an optical axis and light from plus and minus first orders is deflected away from the optical axis, and a second CDW downstream of the first CDW that includes second pixels positioned to receive diffracted orders of light from the first CDW, where there are at least three second pixels for one first pixel corresponding to each diffracted order received from the first pixel. The scene projector may further include a first reflective surface and a second reflective surface each positioned to receive diffracted orders of light from the second CDW, where each reflective surface directs light toward a grating structure. The scene projector may independently control a degree of polarization, angle of linear polarization, and intensity for light output therefrom. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/268980 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class G02F 2203/22 (20130101) G02F 2203/24 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/20 (20130101) G03B 21/2073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656609 | Ilic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Marija Ilic (Sudbury, Massachusetts); Xia Miao (Cambridge, Massachusetts); Rupamathi Jaddivada (Cambridge, Massachusetts) |
| ABSTRACT | Described are concepts, systems and methods for operating microgrid systems both during normal operation conditions and during sudden, unexpected occurrences of a fault which results in a source becoming disconnected from a primary supply. This is achieved through control systems and method based upon multi-layered modeling of system controllable components and their interactions. This approach results in controllable components capable of operation in a “plug-and-play” manner. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965823 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 17/02 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/537 (20130101) H02M 7/53871 (20130101) H02M 2001/0019 (20130101) H02M 2001/0022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656623 | Capobianco, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Vincent John Capobianco, Jr. (Laguna Niguel, California) |
| ABSTRACT | A system is configured to determine the calibration accuracy of an additive manufacturing machine for each of fourteen (14) geometric dimensioning and tolerancing parameters. The system also allows for the comparison of the calibration accuracy of multiple additive manufacturing machines. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/079178 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656885 | Hamlen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Kevin W. Hamlen (Richardson, Texas) |
| ABSTRACT | The present disclosure is directed to a method of creating an object flow integrity (OFI) library module, capable of redirecting an object-like programmatic call, by initiating a multi-pass, recursive process to analyze a module's interfaces, function parameters, and data types. In another aspect, a method is disclosed to modify the binary code of an untrusted module to enable its usage of the OFI library module. In another aspect, during runtime operations of an untrusted module, the OFI library module can receive an object from a caller module, substitute a proxy object, stored in a secure location, and continue the programmatic call using the proxy object. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/173358 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/1222 (20130101) Original (OR) Class G06F 16/1734 (20190101) G06F 21/6209 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 15/4095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657197 | Sharp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Etegent Technologies Ltd. (Cincinnati, Ohio) |
| ASSIGNEE(S) | Etegent Technologies. Ltd. (Cincinnati, Ohio) |
| INVENTOR(S) | Thomas D. Sharp (Terrace Park, Ohio); Richard Allan Roth, II (Cincinnati, Ohio); Uriah M. Ligget (Independence, Kentucky); Joe Kesler (Cincinnati, Ohio) |
| ABSTRACT | Methods manage non-destructive evaluation (“NDE”) data. NDE data for an asset is received and at least one alignment algorithm to align the NDE data to a simulated model associated therewith is determined. The NDE data is automatically aligned to the simulated model, a display representation that visually represents the aligned NDE data on the simulated model is generated, and information about the aligned NDE data is exported. Additionally, second NDE data associated with the at least a portion of the asset may also be received, at least one alignment algorithm to align the data determined, and the second NDE data aligned. Respective indications associated with the first and second NDE data may be determined and visually represented on the simulated model. Moreover, a shot descriptor file may be analyzed to determine whether additional NDE data is required to complete an alignment of NDE data. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/799583 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/10 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658424 | Oliver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | William D. Oliver (Arlington, Massachusetts); Rabindra N. Das (Lexington, Massachusetts); David J. Hover (Somerville, Massachusetts); Danna Rosenberg (Arlington, Massachusetts); Xhovalin Miloshi (Needham, Massachusetts); Vladimir Bolkhovsky (Framingham, Massachusetts); Jonilyn L. Yoder (Billerica, Massachusetts); Corey W. Stull (Leominster, Massachusetts); Mark A. Gouker (Belmont, Massachusetts) |
| ABSTRACT | A superconducting integrated circuit includes at least one superconducting resonator, including a substrate, a conductive layer disposed over a surface of the substrate with the conductive layer including at least one conductive material including a substantially low stress polycrystalline Titanium Nitride (TiN) material having an internal stress less than about two hundred fifty MPa (magnitude) such that the at least one superconducting resonator and/or qubit (hereafter called “device”) is provided as a substantially high quality factor, low loss superconducting device. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/745914 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) Original (OR) Class H01L 39/045 (20130101) H01L 39/223 (20130101) H01L 39/2416 (20130101) H01L 39/2493 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658723 | Kho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Yong Kho (Chula Vista, California); Jia-Chi S. Chieh (San Diego, California) |
| ABSTRACT | A high pass filter includes: an input-impedance-matching taper transition metal layer having an IMT input end and an IMT output end, the IMT input end having an IMT input end width, the IMT output end having an IMT output end width that is wider than the IMT input end width; a substrate integrated waveguide having a SIW input end and a SIW output end; and an output-impedance-matching taper transition metal layer having an OMT input end and an OMT output end, the OMT input end having an OMT input end width, the OMT output end having an OMT output end width that is wider than the OMT input end width. The substrate integrated waveguide is arranged such that the IMT output end is electrically connected to the SIW input end and such that the OMT input end is electrically connected to the SIW output end. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/452182 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/2135 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 23/00 (20130101) Transmission H04B 1/1638 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/025 (20130101) H05K 1/115 (20130101) H05K 1/0242 (20130101) H05K 2201/09827 (20130101) H05K 2201/10098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658741 | Zekios et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ABSTRACT | Multiple-input-multiple-output (MIMO) antenna devices and methods of using and fabricating the same are provided. A MIMO antenna device can include a substrate that is capable of being folded and an antenna element disposed thereon. The antenna element can be disposed on the substrate in a polygon shape such as a rectangle or a square. The substrate can have predefined folding lines such that the substrate can be folded into different positions. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/454448 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658845 | Zhou |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GE Energy Power Conversion Technology Limited (Rugby, Warwickshire, United Kingdom) |
| ASSIGNEE(S) | GE ENERGY POWER CONVERSION TECHNOLOGY LIMITED (Warwickshire, United Kingdom) |
| INVENTOR(S) | Zhi Zhou (Selkirk, New York) |
| ABSTRACT | There is provided a system that includes a processor. The system also includes a memory that stores instructions; when executed by the processor, the instructions configure the processor to perform certain operations. The operations include receiving sensor measurements from an electric power source or device and generating, based on the sensor measurements, a droop control procedure that includes a droop control curve having a non-constant slope. The operations further include regulating a power delivery from the electric power source or device to a bus according to the droop control procedure. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/838101 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/2639 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/28 (20130101) H02J 3/32 (20130101) H02J 3/381 (20130101) H02J 4/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659075 | Inamdar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hypres, Inc. (Elmsford, New York) |
| ASSIGNEE(S) | Hypres Inc. (Elmsford, New York) |
| INVENTOR(S) | Amol Inamdar (Elmsford, New York); Deepnarayan Gupta (Briarcliff Manor, New York) |
| ABSTRACT | Superconductor analog-to-digital converters (ADC) offer high sensitivity and large dynamic range. One approach to increasing the dynamic range further is with a subranging architecture, whereby the output of a coarse ADC is converted back to analog and subtracted from the input signal, and the residue signal fed to a fine ADC for generation of additional significant bits. This also requires a high-gain broadband linear amplifier, which is not generally available within superconductor technology. In a preferred embodiment, a distributed digital fluxon amplifier is presented, which also integrates the functions of integration, filtering, and flux subtraction. A subranging ADC design provides two ADCs connected with the fluxon amplifier and subtractor circuitry that would provide a dynamic range extension by about 30-35 dB. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297571 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/245 (20130101) H03M 1/0854 (20130101) H03M 3/458 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659229 | Smayling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Multibeam Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. Smayling (Fremont, California); David K. Lam (Saratoga, California); Theodore A. Prescop (San Jose, California); Kevin M. Monahan (Cupertino, California) |
| ABSTRACT | Methods, systems and devices for using charged particle beams (CPBs) to write different die-specific, non-volatile, electronically readable data to different dies on a substrate. CPBs can fully write die-specific data within the chip interconnect structure during the device fabrication process, at high resolution and within a small area, allowing one or multiple usefully-sized values to be securely written to service device functions. CPBs can write die-specific data in areas readable or unreadable through a (or any) communications bus. Die-specific data can be used for, e.g.: encryption keys; communications addresses; manufacturing information (including die identification numbers); random number generator improvements; or single, nested, or compartmentalized security codes. Die-specific data and locations for writing die-specific data can be kept in encrypted form when not being written to the substrate to conditionally or permanently prevent any knowledge of said data and locations. |
| FILED | Thursday, February 14, 2019 |
| APPL NO | 16/276047 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 3/067 (20130101) G06F 3/0623 (20130101) G06F 3/0659 (20130101) G06F 21/72 (20130101) G06F 21/73 (20130101) G06F 21/75 (20130101) G06F 21/606 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/263 (20130101) H01L 21/3065 (20130101) H01L 23/544 (20130101) H01L 23/573 (20130101) H01L 2223/54413 (20130101) H01L 2223/54433 (20130101) H01L 2223/54473 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/32 (20130101) Original (OR) Class H04L 9/0861 (20130101) H04L 9/0866 (20130101) H04L 2209/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659558 | Agrawal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dakshi Agrawal (Monsey, New York); Vasileios Pappas (Elmsford, New York); Ramya Raghavendra (White Plains, New York); Mudhakar Srivatsa (White Plains, New York); Dinesh C. Verma (New Castle, New York); Ho Y. Wong (Ossining, New York) |
| ABSTRACT | A method, system and computer program product for transmitting content across a link in a communications network. In an embodiment, the method comprises examining traffic in the network at a sender end of the link to determine if the traffic is carrying compressed content; when the traffic is carrying compressed content, decompressing at least one portion of the compressed content; and checking a cache to determine if the cache has content matching the at least one decompressed portion of the content. In an embodiment, the method further comprises when the cache has content matching the at least one decompressed portion of the content, determining an identifier associated with the at least one decompressed portion of the content; and using the identifier to reconstruct, at a receiving end of the link, the at least one decompressed portion of the content. In one embodiment, the at least one decompressed portion of the content from the traffic is replaced with an index, the index is compressed to form the associated identifier, and the associated identifier is sent to the receiving end of the link. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/147546 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Transmission H04B 1/66 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/06 (20130101) H04L 29/08072 (20130101) H04L 67/2842 (20130101) H04L 67/2885 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10653140 | Davies |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | David G. Davies (Binghamton, New York) |
| ABSTRACT | One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: H3C—(CH2)n—CHm where |
| FILED | Thursday, July 18, 2013 |
| APPL NO | 13/945207 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/02 (20130101) A01N 37/06 (20130101) Original (OR) Class A01N 37/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/361 (20130101) A61K 8/4973 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653638 | Jabbarzadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Ehsan Jabbarzadeh (Columbia, South Carolina); Wesley F. Taylor (Cayce, South Carolina) |
| ABSTRACT | A pimarane diterpenoid, having the following structure: or a tautomer thereof in which R1 and R2 are independently selected from —H, C1-10 alkyl, C1-10 alkoxy, C1-10 alkenyl, C1-10 alkenoxy, —OH, —OAc, —CHO, -Ph, —OC6H5, —OC6H4OH, —COC6H5, —OCONH2, —OCONHCH3, —OCOC6H4NH2, —NH2, or ═O based on an isolate from the plant Hymenocrater elegans is utilized in the prevention of growth and development of pathogenic cells, e.g., cancer cells. The compound shows efficacy in treatment and prevention of a wide range of cancer types as well as other neoplastic diseases as a chemo-preventative, a primary or secondary cytotoxic agent, a sensitizer for other therapies, or one component of a combinatorial treatment. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/004538 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/047 (20130101) Original (OR) Class A61K 31/7072 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653784 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yuan Yao (West Lafayette, Indiana); Jingmin Zhang (West Lafayette, Indiana) |
| ABSTRACT | A material comprising a highly branched carbohydrate polymer, a polyalkylene glycol (or polyalkylene oxide) linked to the highly branched carbohydrate polymer, and a hydrophobic or amphiphilic group linked to the highly branched carbohydrate polymer and/or the polyalkylene glycol (or polyalkylene oxide), is described. Methods of making and using the material, as well as a soluble composition that contains the material and a hydrophobic solute compound, are also described. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/764624 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/1676 (20130101) A61K 9/1682 (20130101) A61K 9/5161 (20130101) A61K 31/12 (20130101) A61K 31/167 (20130101) A61K 31/337 (20130101) A61K 31/343 (20130101) A61K 31/496 (20130101) A61K 31/635 (20130101) A61K 47/36 (20130101) Original (OR) Class A61K 47/38 (20130101) A61K 47/40 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0009 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 2305/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653789 | Camacho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/556798 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653818 | Yoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Yong-Kyu Yoon (Gainesville, Florida); Sheng-Po Fang (Gainesville, Florida) |
| ABSTRACT | Various examples are provided for magnetic particle imbedded nanofibrous membranes. In one example, among others, a nanofibrous membrane includes one or more electrospun nanofibers forming form a layer of nanofibers, and a plurality of magnetic nanoparticles embedded in the one or more electrospun nanofibers. In another example, a method includes generating one or more electrospun nanofibers including magnetic nanoparticles from one or more nozzles positioned over a substrate to form a magnetic nanofibrous layer, and affixing the magnetic nanofibrous layer to a support structure. In another example, a system includes a magnetic nanofibrous membrane affixed to a support structure, and a magnetic field generator configured to generate a magnetic field that passes through the magnetic nanofibrous membrane. |
| FILED | Friday, January 23, 2015 |
| APPL NO | 15/113633 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/042 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/446 (20130101) Original (OR) Class A61L 27/446 (20130101) A61L 2300/102 (20130101) A61L 2400/12 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) D01D 5/0061 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654040 | Khalilabad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Pooyan Tirandazi Khalilabad (Jamaica Plain, Massachusetts); Carlos H. Hidrovo Chaves (Boston, Massachusetts) |
| ABSTRACT | Embodiments are directed to a platform for liquid droplet generation and isolation for biochemical sensing and testing. An embodiment includes generator, fluid-exchange, and manipulator structures that are vertically aligned on a substrate to form a collection chamber. The generator structure is configured to form liquid droplets from a stream of liquid using gas. The fluid-exchange structure is connected to the generator structure to receive the liquid droplets in a carrier liquid held in the collection chamber. The manipulator structure is connected to receive the liquid droplets in the carrier liquid via an inlet. The manipulator structure defines a manipulator chamber connected to the inlet and has a first outlet and a second outlet and a filter capable of filtering the liquid droplets from the carrier liquid. The first outlet enables removal of the liquid droplets filtered and the second outlet enables removal of the carrier liquid. |
| FILED | Friday, August 18, 2017 |
| APPL NO | 15/680659 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502723 (20130101) B01L 3/502753 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/0673 (20130101) B01L 2300/12 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654107 | Manuel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); UTBATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Michele Viola Manuel (Gainesville, Florida); Hunter B. Henderson (Gainesville, Florida); Orlando Rios (Oak Ridge, Tennessee); Gerard M. Ludtka (Oak Ridge, Tennessee) |
| ABSTRACT | Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nickel. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 16/394531 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0044 (20130101) B22F 9/04 (20130101) B22F 9/06 (20130101) Original (OR) Class B22F 2009/042 (20130101) B22F 2009/045 (20130101) B22F 2202/01 (20130101) B22F 2202/05 (20130101) B22F 2202/07 (20130101) B22F 2301/058 (20130101) B22F 2302/10 (20130101) B22F 2302/20 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/1084 (20130101) C22C 1/1084 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/00 (20130101) C25D 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654780 | Jasti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Ramesh Jasti (Eugene, Oregon); Jeff Van Raden (Eugene, Oregon); Erik Leonhardt (Eugene, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of halogenated nanohoop compounds and assemblies thereof that can be used to for a variety of biological and chemical applications. The halogenated nanohoop compounds described herein exhibit non-covalent interactions that promote their ability to stack and form column-like assemblies having uniform pore size and that do not exhibit structural defects typically associated with other column-like structures, such as carbon nanotubes. Assemblies described herein also are capable of non-covalent interactions with other assemblies and thus can be used to form networks of the assemblies described herein. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/900529 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) B01J 20/3085 (20130101) B01J 20/28007 (20130101) B01J 31/0231 (20130101) B01J 35/0006 (20130101) B01J 37/22 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Acyclic or Carbocyclic Compounds C07C 17/263 (20130101) C07C 25/18 (20130101) Original (OR) Class C07C 2603/92 (20170501) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/005 (20130101) H01L 51/0071 (20130101) H01L 51/0093 (20130101) H01L 51/424 (20130101) H01L 51/0558 (20130101) H01L 51/0575 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/60 (20130101) H01M 4/62 (20130101) H01M 4/9008 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654785 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Travis J. Williams (Los Angeles, California); Zhiyao Lu (Duarte, California); Valery Cherepakhin (Los Angeles, California) |
| ABSTRACT | Conversion of vegetable-derived triglycerides to fatty acid methyl esters (FAMEs) is a popular approach to the generation of biodiesel fuels and the basis of a growing industry. Drawbacks of the strategy are that (a) the glycerol backbone of the triglyceride is discarded as waste in this synthesis, and (2) many natural triglycerides are multiply-unsaturated or fully saturated, giving inferior performance and causing engine problems with long-term use. Here, we show that catalysis by iridium complex 1 can address both of these problems through selective reduction of triglycerides high in polyunsaturated fatty esters to FAMEs with high oleate concentration. This is realized using hydrogen imbedded in the triglyceride backbone, concurrently generating lactate as a value-added C3 product. Additional methanol or glycerol as a hydrogen source enables reduction of corn and soybean oils to >80% oleate. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/193590 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) Acyclic or Carbocyclic Compounds C07C 51/09 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 17/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/026 (20130101) C10L 2200/0476 (20130101) C10L 2270/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654875 | McKinlay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Colin J. McKinlay (Alberton, California); Paul A. Wender (Menlo Park, California); Robert M. Waymouth (Palo Alto, California) |
| ABSTRACT | Guanidinium-rich oligophosphotriesters transporter compounds and methods of making and using the same are provided. Also provided are pharmaceutical compositions that include the subject transporter compounds, where the transporter can be joined to a cargo of interest, and is formulated with a pharmaceutically acceptable excipient. Formulations may be provided in a unit dose, where the dose provides an amount of the compound effective to afford a desired therapeutic effect. Methods of using the subject transporter compounds to deliver a cargo moiety to a cell are provided, where the method can include contacting a target cell with the transporter compound. The subject methods can be performed in vitro or in vivo. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/773725 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 47/548 (20170801) A61K 47/605 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) C07F 9/098 (20130101) Original (OR) Class C07F 9/65512 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654879 | Narayan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Sri Narayan (Arcadia, California); Travis J. Williams (Los Angeles, California); Zhiyao Lu (Duarte, California); Debanjan Mitra (Los Angeles, California) |
| ABSTRACT | A compound having formula I that is useful for C═O reduction is provided: wherein: M is a transition metal; X1, X2 are each independently a counterion; and R1, R2, R3 are each independently H, C1-6 alkyl, C6-15 aryl, or C6-15 heteroaryl. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 15/723998 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 29/157 (20130101) C07C 29/159 (20130101) C07C 29/159 (20130101) C07C 31/04 (20130101) C07C 31/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/04 (20130101) Original (OR) Class C07F 15/045 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656016 | Burghoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Burghoff (Cambridge, Massachusetts); Yang Yang (Cambridge, Massachusetts); Qing Hu (Wellesley, Massachusetts) |
| ABSTRACT | According to one aspect, a multi-heterodyne system is disclosed, which comprises a first laser source for generating multi-mode radiation having a frequency spectrum characterized by a first plurality of phase coherent frequencies, and a second laser source for generating multi-mode radiation having a frequency spectrum characterized by a second plurality of phase coherent frequencies. The system further comprises at least one detector for detecting a combination of the multi-mode radiation generated by the first and second laser sources so as to provide a multi-heterodyne signal having a frequency spectrum characterized by a plurality of beat frequencies, each beat frequency corresponding to a pairwise difference in the first and second plurality of phase coherent frequencies. The system further comprises an analyzer for receiving said multi-heterodyne signal and configured to employ a predictive model of the multi-heterodyne signal to provide estimates of any of phase error and timing error associated with the beat frequencies. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148794 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/28 (20130101) Original (OR) Class G01J 3/42 (20130101) G01J 3/108 (20130101) G01J 3/2803 (20130101) G01J 3/4531 (20130101) G01J 9/04 (20130101) G01J 2003/102 (20130101) G01J 2003/284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656493 | Heikenfeld et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Jason Charles Heikenfeld (Cincinnati, Ohio); Sayantika Mukherjee (Cincinnati, Ohio) |
| ABSTRACT | A laminate which can serve as either a smart window or a smart mirror is formed using first and second substrates coated with transparent first and second electrodes which are separated by foraminous layer and a third grid-like linear electrode insulated from the first and second electrodes The foraminous layer includes spacers defining a cell space which is filled with a colloidal ink having first and second particles. The first particles have a positive charge and a first color and second particles having a negative charge and a second color different from the first color. By altering the voltages of the first, second and third electrodes, one can achieve different light transmission characteristics which, for example, can alter the color temperature of the light transmitted through the laminate or enhance reflective colors. |
| FILED | Wednesday, December 02, 2015 |
| APPL NO | 15/552974 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) E06B 2009/2464 (20130101) Optical Elements, Systems, or Apparatus G02B 26/007 (20130101) G02B 26/026 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/167 (20130101) Original (OR) Class G02F 1/1676 (20190101) G02F 2001/1678 (20130101) G02F 2202/28 (20130101) G02F 2203/03 (20130101) G02F 2203/055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656885 | Hamlen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Kevin W. Hamlen (Richardson, Texas) |
| ABSTRACT | The present disclosure is directed to a method of creating an object flow integrity (OFI) library module, capable of redirecting an object-like programmatic call, by initiating a multi-pass, recursive process to analyze a module's interfaces, function parameters, and data types. In another aspect, a method is disclosed to modify the binary code of an untrusted module to enable its usage of the OFI library module. In another aspect, during runtime operations of an untrusted module, the OFI library module can receive an object from a caller module, substitute a proxy object, stored in a secure location, and continue the programmatic call using the proxy object. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/173358 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/1222 (20130101) Original (OR) Class G06F 16/1734 (20190101) G06F 21/6209 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 15/4095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657385 | Laput et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania); University of Rochester (New York, New York) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Pro fit Corporation (Pittsburgh, Pennsylvania); UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Gierad Laput (Pittsburgh, Pennsylvania); Christopher Harrison (Pittsburgh, Pennsylvania); Jeffrey P. Bigham (Pittsburgh, Pennsylvania); Walter S. Lasecki (Ann Arbor, Michigan); Bo Robert Xiao (Pittsburgh, Pennsylvania); Jason Wiese (San Francisco, California) |
| ABSTRACT | The disclosure describes a sensor system that provides end users with intelligent sensing capabilities, and embodies both crowd sourcing and machine learning together. Further, a sporadic crowd assessment is used to ensure continued sensor accuracy when the system is relying on machine learning analysis. This sensor approach requires minimal and non-permanent sensor installation by utilizing any device with a camera as a sensor host, and provides human-centered and actionable sensor output. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/561407 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 3/01 (20130101) G06F 17/18 (20130101) G06F 40/40 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/036 (20130101) G06K 9/00771 (20130101) Original (OR) Class G06K 9/00993 (20130101) G06K 9/6212 (20130101) G06K 9/6259 (20130101) G06K 9/6262 (20130101) Computer Systems Based on Specific Computational Models G06N 5/041 (20130101) G06N 20/00 (20190101) G06N 20/10 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657494 | Juola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Patrick Juola (Pittsburgh, Pennsylvania); James Orlo Overly (Punxsutawney, Pennsylvania); John Isaac Noecker, Jr. (Schuylkill Haven, Pennsylvania); Michael Ryan (Pittsburgh, Pennsylvania); Christine Gray (Jefferson Hills, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Patrick Juola (Pittsburgh, Pennsylvania); James Orlo Overly (Punxsutawney, Pennsylvania); John Isaac Noecker, Jr. (Schuylkill Haven, Pennsylvania); Michael Ryan (Pittsburgh, Pennsylvania); Christine Gray (Jefferson Hills, Pennsylvania) |
| ABSTRACT | Novel distractorless authorship verification technology optionally combines with novel algorithms to solve authorship attribution as to an open set of candidates—such as without limitation by analyzing the voting of “mixture of experts” and outputting the result to a user using the following: if z (z=pi−pj√pi+pj−(pi−pj)2/n) is larger than a first predetermined threshold then author j cannot be the correct author; or if z (z=pi−pj√pi+pj−(pi−pj)2/n) is smaller than a second predetermined threshold then author i cannot be the correct author; or if no author garners significantly more votes than all other contenders then none of the named authors is the author of a document in question—in a number of novel applications. Personality profiling and authorship attribution may also be used to verify user identity to a computer. |
| FILED | Friday, May 04, 2012 |
| APPL NO | 14/114956 |
| ART UNIT | 3688 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) G06F 40/253 (20200101) G06F 2221/2131 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Original (OR) Class G06Q 50/184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657651 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Jia Li (State College, Pennsylvania); James Z. Wang (State College, Pennsylvania) |
| ABSTRACT | Systems, methods, and computer-readable media for electronically assessing a visual significance of pixels or regions in an electronic image are disclosed. A method includes receiving the electronic image, performing a composition analysis on the electronic image, the composition analysis includes partitioning the electronic image into a plurality of segments or a plurality of parts, constructing an attributed composition graph having a plurality of nodes, where each node corresponds to a segment or a part and where each node includes one or more attributes, modeling the visual significance of the electronic image based on the attributed composition graph using a statistical modeling process or a computational modeling process to obtain a plurality of values, and constructing a composition significance map having a significance score for each segment or each part according to the values obtained from the statistical modeling process or the computational modeling process. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/212942 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/12 (20170101) G06T 7/143 (20170101) Original (OR) Class G06T 7/162 (20170101) G06T 7/194 (20170101) G06T 2207/10024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657802 | Guerin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Kelleher Guerin (Baltimore, Maryland); Gregory Hager (Baltimore, Maryland) |
| ABSTRACT | Provided is a method, device, and computer-readable medium for controlling a robot graphic user interface (“RGUI”) on a mobile device. The method can include determining a distance, a position, or both of the mobile device with respect to a first robot; and causing, by a processor, a first RGUI to be displayed on a display of the mobile device based on the determining. |
| FILED | Wednesday, November 02, 2016 |
| APPL NO | 15/341136 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/409 (20130101) G05B 2219/39384 (20130101) G05B 2219/40382 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101) Original (OR) Class G08C 2201/20 (20130101) G08C 2201/30 (20130101) G08C 2201/70 (20130101) G08C 2201/91 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657948 | Braasch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Jonas Braasch (Latham, New York); Alana Gloria DeLoach (Troy, New York); Jeffrey Parkman Carter (Cohoes, New York) |
| ABSTRACT | A system, method and program product for generating sound masking in an open-plan space. A method is disclosed that includes: establishing a set of acoustic criteria for the space that specifies minimum output levels at a set of specified frequencies; mixing sound samples to create an audio output stream for use as sound masking when broadcast over at least one speaker using a power amplifier; and processing the audio output stream, wherein the processing includes: analyzing the audio output stream with a spectrum analyzer to determine if the minimum output levels at the set of specified frequencies are met; and level adjusting the audio output stream with an equalizer to ensure that minimum output levels at the set of specified frequencies are met but do not exceed a given threshold above the minimum level. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568909 |
| ART UNIT | 2655 — Digital Audio Data Processing |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/175 (20130101) Original (OR) Class Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/18 (20130101) Control of Amplification H03G 5/165 (20130101) Secret Communication; Jamming of Communication H04K 3/42 (20130101) H04K 3/43 (20130101) H04K 3/84 (20130101) H04K 3/94 (20130101) H04K 3/825 (20130101) H04K 2203/12 (20130101) H04K 2203/34 (20130101) H04K 2203/36 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 3/04 (20130101) H04R 29/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658091 | Kandel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Hom Kandel (Tallahassee, Florida); Jun Lu (Tallahassee, Florida) |
| ABSTRACT | A coating mixture comprising at least one ceramic powder and a first and second binder that when applied to a substrate and heat treated produces a thin ceramic electrical insulation coating suitable for superconducting magnet applications. |
| FILED | Monday, July 14, 2014 |
| APPL NO | 14/330326 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/0254 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/46 (20130101) H01B 3/447 (20130101) H01B 3/448 (20130101) Original (OR) Class H01B 12/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658567 | Merrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nano Composite Products, Inc. (Orem, Utah) |
| ASSIGNEE(S) | NANO COMPOSITE PRODUCTS, INC. (Orem, Utah) |
| INVENTOR(S) | Aaron Jake Merrell (Orem, Utah); David T. Fullwood (Provo, Utah); Anton E. Bowden (Lindon, Utah); Taylor D. Remington (Provo, Utah) |
| ABSTRACT | In one general aspect, an apparatus comprises a material including a non-layered mixture of an polymeric foam with a plurality of voids; and a plurality of conductive fillers disposed in the polymeric foam. The apparatus may produce an electrical response to deformation and, thus, function as a strain gauge. The electrical response may be a decrease in electrical resistance. The electrical response may be an electric potential generated. The conductive fillers may include conductive nanoparticles and/or conductive stabilizers. In another general aspect, a method of measuring compression strain includes detecting, along a first axis, an electrical response generated in response to an impact to a uniform composite material that includes conductive fillers and voids disposed throughout an elastomeric polymer, and determining a deformation of the impact based on the electrical response. The impact may be along a second axis different from the first axis. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384609 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) G01L 1/18 (20130101) G01L 1/20 (20130101) G01L 5/0052 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/37 (20130101) H01L 41/183 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658920 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Jiangbiao He (Schenectady, New York); Nabeel A. O. Demerdash (New Berlin, Wisconsin) |
| ABSTRACT | Systems and methods of fault tolerant power conversion include an inverter with a plurality of inverter phase legs. Each phase leg includes a positive switch, a negative switch, and a bi-directional midpoint switch. Redundant phase leg includes a positive redundant switch connected between the positive switches and the bi-directional midpoint switches. The redundant phase leg includes a negative redundant switch connected between the negative switches and the bi-directional midpoint switches. Upon detection of a fault condition in at least one switch of the plurality of inverted phase legs, one of the positive redundant switch and the negative redundant switch is closed to bypass at least one switch with the fault condition to maintain operation of the power converter. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/775246 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 1/083 (20130101) H02M 7/487 (20130101) H02M 7/5395 (20130101) H02M 2001/0058 (20130101) H02M 2001/325 (20130101) H02M 2001/327 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/08 (20130101) H02P 29/028 (20130101) H02P 29/032 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659328 | Sundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vinaitheerthan Sundaram (West Lafayette, Indiana); Patrick Eugster (West Lafayette, Indiana); Xiangyu Zhang (West Lafayette, Indiana) |
| ABSTRACT | A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. The stored packet-identification value is then increased and the process repeats. To receive data, an expected identification value is stored in association with the identifier. A packet and a packet-identification value are received from the network device. The identifier and an indication of receipt are stored. If the received value does not match the expected value for the identifier, the received value is stored. If the values match, the stored packet-identification value and identifier are recorded. If the received value exceeds the expected value, the stored packet-identification value, the identifier and the received identifier are recorded. Subsequently, the stored expected value is increased. The process repeats. Network devices and systems are described. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367383 |
| ART UNIT | 2466 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3636 (20130101) G06F 16/1744 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) Original (OR) Class H04L 45/74 (20130101) H04L 69/04 (20130101) H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10654009 | Yelvington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| ASSIGNEE(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| INVENTOR(S) | Paul E. Yelvington (Rockledge, Florida); Nicholas R. Schwartz (Rockledge, Florida); Michael J. Blaise (Melbourne, Florida) |
| ABSTRACT | A Venturi draft tube spouted bed and method are disclosed that enables scale-up with small particles and improves heat and mass transfer by increasing material turnover rate. A Venturi-style eductor has been incorporated into the spouted bed draft tube to provide suction at the bottom of the bed to better entrain material and reduce the propensity for dead zones at the bottom of the narrow conical section. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906299 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/043 (20130101) Original (OR) Class B01F 2003/125 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/006 (20130101) B01J 2/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654107 | Manuel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); UTBATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Michele Viola Manuel (Gainesville, Florida); Hunter B. Henderson (Gainesville, Florida); Orlando Rios (Oak Ridge, Tennessee); Gerard M. Ludtka (Oak Ridge, Tennessee) |
| ABSTRACT | Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nickel. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 16/394531 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0044 (20130101) B22F 9/04 (20130101) B22F 9/06 (20130101) Original (OR) Class B22F 2009/042 (20130101) B22F 2009/045 (20130101) B22F 2202/01 (20130101) B22F 2202/05 (20130101) B22F 2202/07 (20130101) B22F 2301/058 (20130101) B22F 2302/10 (20130101) B22F 2302/20 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/1084 (20130101) C22C 1/1084 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/00 (20130101) C25D 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654772 | Vajda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Stefan Vajda (Lisle, Illinois); Avik Halder (Clarendon Hills, Illinois); Larry A. Curtiss (Downers Grove, Illinois) |
| ABSTRACT | The invention provides a method for generating alkenes, the method having the steps of contacting an alkane with catalyst clusters no greater than 10 nm for a time sufficient to convert the alkane to alkene. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/128105 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/72 (20130101) Acyclic or Carbocyclic Compounds C07C 5/48 (20130101) Original (OR) Class C07C 11/06 (20130101) C07C 2521/18 (20130101) C07C 2523/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655233 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kyoung-Shin Choi (Fitchburg, Wisconsin); Hyun Gil Cha (Madison, Wisconsin) |
| ABSTRACT | Electrochemical and photoelectrochemical cells for the oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid and/or 2,5-diformylfuran are provided. Also provided are methods of using the cells to carry out the electrochemical and photoelectrochemical oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid and/or 2,5-diformylfuran. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/421750 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/02 (20130101) Original (OR) Class C25B 9/00 (20130101) C25B 9/06 (20130101) C25B 11/12 (20130101) C25B 11/0405 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2004 (20130101) H01G 9/2027 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101) Y02E 60/366 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/135 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655541 | Berry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schnectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Michael John Hughes (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to a segmented annular combustion system including a first panel fuel injector including a premix air plenum, a fuel plenum, and a plurality of first side premixing channels, where each first side premixing channel is in fluid communication with the premix air plenum, the fuel plenum, and a respective first side injection aperture of a plurality of first side injection apertures. A second panel fuel injector is circumferentially spaced from the first panel fuel injector and includes a premix air plenum, a fuel plenum, and a plurality of second side premixing channels where each second side premixing channel is in fluid communication with the premix air plenum, the fuel plenum, and a respective second side injection aperture of a plurality of second side injection apertures. A fuel nozzle is disposed circumferentially between the first panel fuel injection and the second panel fuel injector. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/442292 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/22 (20130101) F02C 7/222 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/005 (20130101) F23R 3/06 (20130101) F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/34 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655911 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho); Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Klingler (Idaho Falls, Idaho) |
| ASSIGNEE(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho); Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Klingler (Idaho Falls, Idaho) |
| ABSTRACT | A method of liquefying natural gas. The method comprises cooling a gaseous natural gas process stream with a refrigerant flowing in a path isolated from the natural gas process stream. The refrigerant may differ in composition from a composition of the natural gas process stream, and the refrigerant composition may be selected to enhance efficiency of the refrigerant path with regard to a specific composition of the natural gas process stream. The refrigeration path may be operated at pressures, temperatures and flow rates differing from those of the natural gas process stream. Other methods of liquefying natural gas are described. A natural gas liquefaction plant is also described. |
| FILED | Wednesday, June 20, 2012 |
| APPL NO | 13/528246 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 1/004 (20130101) F25J 1/005 (20130101) F25J 1/0022 (20130101) Original (OR) Class F25J 1/025 (20130101) F25J 1/0042 (20130101) F25J 1/0045 (20130101) F25J 1/0052 (20130101) F25J 1/0204 (20130101) F25J 1/0208 (20130101) F25J 1/0212 (20130101) F25J 1/0219 (20130101) F25J 2205/10 (20130101) F25J 2205/20 (20130101) F25J 2205/84 (20130101) F25J 2210/06 (20130101) F25J 2220/66 (20130101) F25J 2235/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10655939 | Ripley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Reston, Virginia) |
| ASSIGNEE(S) | Consolidate Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Edward B. Ripley (Knoxville, Tennessee); Jacob Miller (Oliver Springs, Tennessee); Michael J. Renner (Oak Ridge, Tennessee); Walter Duerksen (Norris, Tennessee); Jonathan Morrell (Knoxville, Tennessee) |
| ABSTRACT | A thermal protection barrier including a base layer having a plurality of baffles with perforated walls and a high melting temperature granular media disposed within the plurality of baffles. When the base layer is breached by a thermal threat, the granular media is operable to flow through the perforated walls of the plurality of baffles to provide a controlled flow of granular media to an area proximate the breach for thwarting the thermal threat. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994055 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 5/16 (20130101) B32B 5/18 (20130101) B32B 9/007 (20130101) B32B 9/048 (20130101) B32B 18/00 (20130101) B32B 2264/12 (20130101) B32B 2264/102 (20130101) B32B 2264/108 (20130101) B32B 2266/0214 (20130101) B32B 2307/306 (20130101) B32B 2307/714 (20130101) B32B 2315/02 (20130101) B32B 2325/00 (20130101) B32B 2375/00 (20130101) B32B 2571/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/941 (20130101) E04B 2103/02 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0428 (20130101) Original (OR) Class F41H 5/0492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656116 | Burge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott R. Burge (Tempe, Arizona); Russell G. Burge (Mountain View, California); David A. Hoffman (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott R. Burge (Tempe, Arizona); Russell G. Burge (Mountain View, California); David A. Hoffman (Tempe, Arizona) |
| ABSTRACT | A microbial sensor, system, and method that can be used to determine a chemical environment and/or substrate concentrations in anaerobic or aerobic environments, such as soils, sediments and ground waters, are disclosed. An exemplary system uses one or more (e.g., inert) measurement electrodes and a reference electrode. The reference electrode can include an electrode exposed to atmospheric oxygen (e.g., a cathode) or an electrode exposed to stable anaerobic or aerobic conditions. The exemplary microbial sensor system measures open-circuit voltage to characterize the chemical (oxidizing or reducing) environment and/or recovery voltage to measure substrate concentrations in the subsurface. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125488 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 27/4035 (20130101) G01N 27/4163 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656287 | Gotthold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | David W. Gotthold (Richland, Washington); Andrew J. Stevens (Richland, Washington); Nigel D. Browning (Richland, Washington); Eric Jensen (Richland, Washington); Nathan L. Canfield (Richland, Washington); Alan G. Joly (Richland, Washington) |
| ABSTRACT | A method includes directing a probe beam to a target that includes an array of data portions in a data storage medium arranged so that a beam area of the probe beam extends across a plurality of adjacent data portions, the array including a data portion subset with each data portion of the subset responsive to the probe beam to produce a response illumination, receiving the response illumination at a detector, and determining data values corresponding to the plurality of adjacent data portions based on the received response illumination. Apparatus and systems are also disclosed. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374358 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/00 (20130101) G01T 1/115 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/0325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656443 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire); LaXense Inc. (Walnut, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); LAXENSE INC. (Walnut, California); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jifeng Liu (Hanover, New Hampshire); Xiaoxin Wang (Hanover, New Hampshire); Juejun Hu (Newton, Massachusetts); Xiaochen Sun (Chino Hills, California); Tian Gu (Fairfax, Virginia) |
| ABSTRACT | An optical interconnect system has first and second waveguides each with wedge-shaped cross-section at a first end, disposed over an optical modulator. The optical modulator is a surface-plasmon multi quantum well (SP-MQW) modulator, the first waveguide an input waveguide and the second waveguide configured an output waveguide. In embodiments the SP-MQW modulator has multiple semiconductor layers disposed atop a lower metal layer between 10 and 300 nanometers thick and configured such that incident light is reflected at the lower metal layer unless a voltage is applied to the semiconductor layers, when incident light is coupled into a surface plasmon mode in the lower metal layer. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923986 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/017 (20130101) Original (OR) Class G02F 2001/0151 (20130101) G02F 2001/0157 (20130101) G02F 2202/101 (20130101) G02F 2202/108 (20130101) G02F 2203/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657301 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Byoung Park (Albuquerque, New Mexico); Barry L. Roberts (Edgewood, New Mexico); Steven R. Sobolik (Albuquerque, New Mexico); Moo Y. Lee (Placitas, New Mexico) |
| ABSTRACT | Systems, methods and computer program products for creating 3D representations of bodies are disclosed. The systems, methods and computer program products include the construction of FE meshes representing complex geometries. The complex geometries may be artificially or naturally formed or designed geometries. The techniques reduce the number of elements as much as possible to save on computer run time while maintaining computational accuracy. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/435904 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/0088 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/00 (20141201) Electric Digital Data Processing G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657456 | Kharzeev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York) |
| ASSIGNEE(S) | BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Dmitri Kharzeev (Port Jefferson, New York); Qiang Li (Upton, New York) |
| ABSTRACT | An apparatus for performing quantum computing includes multiple qubits, each of at least a subset of the qubits comprising a loop formed of a Dirac or Weyl semimetal and having at least two stable quantum states. The apparatus further includes at least one terahertz cavity coupled with the qubits, the terahertz cavity being configured to detect the quantum states of the qubits. Each of at least the subset of qubits is configured to receive a circularly polarized radiation source. The radiation source is adapted to excite a chiral current in each of at least the subset of qubits, the quantum states of the plurality of qubits being a function of the chiral current. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443170 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658170 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eden Park Illumination (Champaign, Illinois) |
| ASSIGNEE(S) | Eden Park Illumination (Champaign, Illinois) |
| INVENTOR(S) | Sung-Jin Park (Champaign, Illinois); Cyrus M. Herring (Urbana, Illinois); James Gary Eden (Champaign, Illinois) |
| ABSTRACT | A plasma lamp includes plates that are approximately parallel, with at least one array of microcavities formed in a surface of at least one plate. When desirable, the plates are separated a fixed distance by spacers with at least one spacer being placed near the plate's edge to form a hermetic seal therewith. A gas makes contact with the microcavity array. Electrodes capable of delivering a time-varying voltage are located on the surface of each plate. At least one electrode is located on an exterior surface of at least one interior plate. Optionally, protective windows may be placed over the electrodes. The application of the time-varying voltage interacts with the gas to form a glow discharge plasma in the microcavities and the fixed volume between the plates (when present). The glow discharge plasma efficiently and uniformly emits UV/VUV radiation over the entire surface of the lamp. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 16/312540 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/26 (20130101) A61L 2202/11 (20130101) A61L 2202/24 (20130101) A61L 2202/26 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 2201/3228 (20130101) C02F 2303/04 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 25/12 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/39 (20130101) H01J 9/248 (20130101) H01J 9/268 (20130101) H01J 11/12 (20130101) H01J 11/18 (20130101) H01J 11/36 (20130101) H01J 11/38 (20130101) H01J 61/16 (20130101) H01J 61/025 (20130101) H01J 61/42 (20130101) H01J 61/125 (20130101) H01J 61/305 (20130101) Original (OR) Class H01J 65/046 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658560 | Morelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Donald T. Morelli (White Lake, Michigan); Xu Lu (Lansing, Michigan); Vidvuds Ozolins (Los Angeles, California) |
| ABSTRACT | Thermoelectric materials based on tetrahedrite structures for thermoelectric devices and methods for producing thermoelectric materials and devices are disclosed. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604011 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/547 (20130101) C04B 35/645 (20130101) C04B 35/6262 (20130101) C04B 35/62645 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/81 (20130101) C04B 2235/662 (20130101) C04B 2235/3262 (20130101) C04B 2235/3272 (20130101) C04B 2235/3281 (20130101) C04B 2235/3284 (20130101) C04B 2235/3291 (20130101) C04B 2235/3294 (20130101) C04B 2235/6562 (20130101) C04B 2235/6565 (20130101) C04B 2235/6567 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class H01L 35/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658678 | Tong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | YuYe J. Tong (Gaithersburg, Maryland); Dejun Chen (Arlington, Virginia) |
| ABSTRACT | Provided are electrocatalysts, fuel cells, methods of making fuel cells, and methods of generating an electric current, each featuring a platinum (Pt)-containing substrate in contact with an aqueous solution comprising Pb2+. Electrocatalysts of the invention are formed via underpotential deposition (UPD) when a trace amount of Pb2+ is present in the electrolyte of a half anodic cell for oxidizing formic acid using Pt as the anode. Surprisingly, the UPD process dramatically enhances the activity of formic acid oxidation, at least as much as 10-fold compared with palladium (Pd) black. In an embodiment, the electrocatalyst comprises a Pt-containing substrate, a submonolayer of lead (Pb) adsorbed onto the Pt-containing substrate, and an aqueous solution comprising Pb2+, wherein the concentration of Pb2+ in the aqueous solution is 10 to 500 μm. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 14/739063 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) H01M 4/926 (20130101) Original (OR) Class H01M 8/1009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658848 | Brushett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Fikile Richard Brushett (Cambridge, Massachusetts); Andrew Norbert Jansen (Bolingbrook, Illinois); John Thomas Vaughey (Elmhurst, Illinois); Liang Su (Medfield, Massachusetts); Jarrod D. Milshtein (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are redox flow batteries comprising a first aqueous electrolyte comprising a first type of redox active material and a second aqueous electrolyte comprising a second type of redox active material. The first type of redox active material may comprise one or more types of quinoxalines, or salts thereof. Methods for storing and releasing energy utilizing the described redox flow batteries are also provided. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 15/785009 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/608 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/0215 (20130101) H01M 8/0236 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658941 | Dame et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Mark Dame (Niskayuna, New York); Jiangbiao He (Niskayuna, New York); Di Zhang (Niskayuna, New York) |
| ABSTRACT | In an embodiment, a three-level active neutral-point clamped (ANPC) converter system is provided. The system includes first and second Direct Current (DC)-bus structures that include at least one of a number of DC-bus capacitors on printed circuit boards (PCBs). The PCBs are laminated together with an air gap (e.g., one or more millimeters) in between for a thermal dissipation and an insulation creepage. The three DC-bus terminals include PCBs, and are electrically connected to the three-level power converter, which are typically mounted on a heatsink or a cold plate. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955064 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/003 (20130101) Original (OR) Class H02M 7/487 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/144 (20130101) H05K 1/0231 (20130101) H05K 7/209 (20130101) H05K 2201/042 (20130101) H05K 2201/10015 (20130101) H05K 2201/10272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659314 | Dearien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| ASSIGNEE(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| INVENTOR(S) | Jason A. Dearien (Moscow, Idaho); Rhett Smith (Kuna, Idaho); Marc Ryan Berner (Monroe, Washington) |
| ABSTRACT | The present disclosure pertains to systems and methods for automating the configuration of communication hosts in a software defined network (SDN) associated with an electric power transmission and distribution system. The systems and methods presented herein may utilize communication host profiles to specify various repeatable attributes and customizable attributes that may be utilized to configure the communication host and the SDN. In one embodiment, a system may comprise a communication host profile subsystem configured to select a communication host profile associated with a communication host. The host communication profile subsystem may configure the communication host based on one or more repeatable attributes and on one or more customizable attributes specified in the host communication profile. A traffic routing system may further configure a plurality of communication flows in the SDN based on the communication host based on the host communication profile. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/803688 |
| ART UNIT | 2442 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/20 (20130101) Original (OR) Class H04L 43/0829 (20130101) H04L 43/0864 (20130101) H04L 67/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659476 | Ramanujan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Ranga Ramanujan (Medina, Minnesota); Benjamin L. Burnett (Prior Lake, Minnesota) |
| ABSTRACT | This disclosure is directed to monitoring a crypto-partitioned, or cipher-text, wide-area network (WAN). A first computing device may be situated in a plain-text portion of a first enclave behind a first inline network encryptor (INE). A second device may be positioned in a plain-text portion of a second enclave behind a second INE. The two enclaves may be separated by a cipher-text WAN, over which the two enclaved may communicate. The first computing device may receive a data packet from the second computing device. The first computing device may then determine contents of a header of the data packet. The first computing device may, based at least in part on the contents of the header of the data packet, determine a status of the cipher-text WAN. |
| FILED | Monday, September 12, 2016 |
| APPL NO | 15/262979 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2854 (20130101) H04L 63/1408 (20130101) Original (OR) Class H04L 63/1441 (20130101) H04L 63/1458 (20130101) H04L 63/1483 (20130101) H04L 69/22 (20130101) H04L 2463/121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10653280 | Torres et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Miguel Angel Torres (S. Windsor, Connecticut); Thomas J. Stapleton (Southwick, Massachusetts) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Miguel Angel Torres (S. Windsor, Connecticut); Thomas J. Stapleton (Southwick, Massachusetts) |
| ABSTRACT | A method of treating fecal waste according to an example of the present disclosure includes bringing a reactor containing fecal matter to a first temperature and a first pressure, exposing the reactor to an environment with a second temperature and a second pressure such that the water in the fecal waste undergoes flash evaporation, and pyrolizing the fecal waste. A fecal waste processing unit is also disclosed. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872533 |
| ART UNIT | 3754 — Fluid Handling and Dispensing |
| CURRENT CPC | Sanitary Equipment Not Otherwise Provided for; Toilet Accessories A47K 11/023 (20130101) Original (OR) Class Presses in General B30B 1/32 (20130101) B30B 9/04 (20130101) B30B 15/34 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) Gathering or Removal of Domestic or Like Refuse B65F 1/1405 (20130101) Cremation Furnaces; Consuming Waste Products by Combustion F23G 5/0276 (20130101) F23G 2202/30 (20130101) F23G 2203/60 (20130101) F23G 2900/7003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654592 | Mata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Marianne E. Mata (Chicago, Illinois); Martin E. Lozano (Chicago, Illinois); Tyler C. Staudinger (Chicago, Illinois); John H. Blumer (Chicago, Illinois); Mark W. Henley (Chicago, Illinois) |
| ABSTRACT | A fuel cell-based power system comprises a fuel cell configured for continuously receiving a first reactant and a second reactant to produce chemical reactions that generate electrical power, water, and heat, a coolant subsystem configured for circulating a primary coolant in association with the fuel cell, thereby absorbing the generated heat, a tank configured for storing a reactant, and a reactant distribution subsystem configured for conveying the reactant from the tank to an independent system, the fuel cell as the first reactant, and the coolant subsystem as a secondary coolant to remove the absorbed heat from the primary coolant and/or a water accumulator. The secondary coolant may be conveyed to a gas thruster as a gas after the absorbed heat has been removed from the secondary coolant. The reactant may be boil off of a cryogenic liquid or vapor or gas transformed from a cryogenic liquid via a heater. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/043437 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/42 (20130101) Original (OR) Class B64G 1/402 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04014 (20130101) H01M 8/04208 (20130101) H01M 8/04701 (20130101) H01M 2250/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Y02T 50/62 (20130101) Y02T 90/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654593 | Veselka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Dennis Veselka (Oviedo, Florida); John B. Lauger (Webster, Texas); Brian R. Dunaway (League City, Texas); Daniel J. Leonard (Seabrook, Texas) |
| ABSTRACT | A pressure control system includes at least one tank storing a mixture of oxygen and nitrogen. The system further includes a first branch of a pressure control line configured to transport a first portion of the mixture of oxygen and nitrogen to a pressurized enclosed volume. The system also includes a second branch of the pressure control line configured to transport a second portion of the mixture of oxygen and nitrogen to at least one flight suit removably coupled to the second branch. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655756 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/50 (20130101) Original (OR) Class B64G 1/60 (20130101) B64G 6/00 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/02 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 7/00 (20130101) F17C 13/04 (20130101) F17C 2205/0332 (20130101) F17C 2221/03 (20130101) F17C 2270/0186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10654756 | Raj |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Sai V. Raj (Strongsville, Ohio) |
| ABSTRACT | An engineered ceramic matrix is provided to blunt and self-heal matrix cracks to reduce oxygen ingress into a fiber reinforced composite. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875283 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/657 (20130101) C04B 35/806 (20130101) Original (OR) Class C04B 35/6261 (20130101) C04B 35/6264 (20130101) C04B 41/009 (20130101) C04B 41/87 (20130101) C04B 41/5064 (20130101) C04B 2235/606 (20130101) C04B 2235/616 (20130101) C04B 2235/728 (20130101) C04B 2235/3826 (20130101) C04B 2235/3873 (20130101) C04B 2235/3891 (20130101) C04B 2235/5244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656109 | Fesmire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | James E. Fesmire (Titusville, Florida); Wesley L. Johnson (Middleburg Heights, Ohio); Jared P. Sass (Rockledge, Florida) |
| ABSTRACT | A test apparatus for evaluating thermal properties of a test specimen across a wide range of thermal conductivities and temperature ranges using a flat plate cup cryostat. The test apparatus includes: a heater assembly having an upper surface to receive a test specimen; a cold plate positioned on top of the test specimen; a vessel comprising an outer cylindrical tube closed on a bottom end by the cold plate; an inner cylindrical tube concentrically received in an upper portion of the outer cylindrical tube above the vessel to vent the vessel; insulation material surrounding at least the heater assembly, test specimen, cold plate, and vessel; a sensor that detects boiloff or evaporation rate of liquid from the vessel vented from the inner cylindrical tube; temperature sensors positioned to detect temperatures of the heater assembly and the cold plate; and a data recording device to record the boiloff or evaporation rates and temperature values. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/603393 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656131 | Bailey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Steven A. Bailey (Gambrills, Maryland); Thomas Hanisco (Takoma Park, Maryland) |
| ABSTRACT | Cavity enhanced absorption spectroscopy (CEAS) may include a pulsed light emitting diode (LED) configured to emit a light towards a photomultiplier tube (PMT). CEAS may also include a cell, which includes a pair of reflective mirrors located at opposite ends of the cell. The pair of mirrors are configured to bounce the light back and forth a plurality of times increasing the effective path length of the cell. The PMT is configured to detect the emitted light for ozone absorption measurement. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/109093 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 33/0039 (20130101) Original (OR) Class G01N 2021/1704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657371 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sabrina N. Thompson (Greenbelt, Maryland); Sean R. Semper (Greenbelt, Maryland); Philip C. Calhoun (Greenbelt, Maryland); Neerav Shah (Greenbelt, Maryland) |
| ABSTRACT | A miniaturized astrometric alignment sensor may detect stellar objects and targets from which both stellar and object tracking are performed. The sensor may search for one or more bright opens in an image captured by a camera of a space vehicle, and determine if the one or more bright objects is a genuine star or a secondary element. The sensor may also catalog entries of identified stars after three or more bright objects are determined to be genuine stars, and display the cataloged entries of the identified stars, wherein the cataloged entries comprises positional and velocity of the space vehicle in relation of the identified stars and a sensor body reference frame. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/145570 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/025 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/40 (20130101) G06K 9/0063 (20130101) Original (OR) Class G06K 9/4647 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 7/246 (20170101) G06T 2207/10032 (20130101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657716 | Clausen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Matthew C. Clausen (Los Angeles, California); Charles Goddard (Los Angeles, California); Garrett K. Johnson (Pasadena, California); Marsette A. Vona, III (Los Angeles, California); Victor X. Luo (Pasadena, California); Jeffrey S. Norris (Saratoga, California); Anthony J. Valderrama (Pasadena, California) |
| ABSTRACT | A method, apparatus, and system provide the ability to control navigation of a three-dimensional (3D) computer aided design (CAD) model in an augmented reality space. The 3D CAD model is rendered in the augmented reality space and appears as if it is present in a physical space at true scale. A virtual camera is defined as fixed to a current pose of a user's head. A virtual line segment S is constructed coincident with a ray R from a center of projection P of the virtual camera and a center pixel of the virtual camera. A check for geometric intersections between the virtual line segment S and surfaces of scene elements is conducted. Upon intersecting with a part of the model, a gaze cursor is rendered at an intersection point C closest to the center of projection P. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914692 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/017 (20130101) G06F 3/0482 (20130101) Image Data Processing or Generation, in General G06T 19/003 (20130101) Original (OR) Class G06T 19/006 (20130101) G06T 19/20 (20130101) G06T 2210/21 (20130101) G06T 2219/004 (20130101) G06T 2219/024 (20130101) G06T 2219/2016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10658756 | Marrero-Fontanez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Victor J. Marrero-Fontanez (Greenbelt, Maryland); Cornelis F. Du Toit (Ellicott City, Maryland) |
| ABSTRACT | An earth coverage antenna system includes a reflector, a feed horn and a strut. The reflector has a circularly symmetric reflector surface. The feed horn is positioned on the symmetry axis of the reflector and is attached to the strut. The feed horn transmits RF microwave energy toward the reflector surface. The antenna system further includes two cables that prevent side-ways movement of the strut. The antenna system further includes a lens assembly that directs microwave energy away from the central region of the reflector. The antenna system further includes a microwave energy scattering device disposed at the center of the reflector to scatter microwave energy away from the feed horn. The reflector surface is defined by a perturbed parabolic geometrical shape that is swept around the symmetry axis. The reflector reflects most microwave energy towards the earth's horizon, but diverts enough microwave energy towards the regions closer to nadir so as to maintain an isoflux of energy on the earth's surface. The reflector shape is optimized to minimize flux ripples caused by interference of the microwave energy scattered from the microwave energy scattering device. |
| FILED | Thursday, December 28, 2017 |
| APPL NO | 15/857021 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/288 (20130101) H01Q 3/2664 (20130101) H01Q 15/147 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659094 | Knuble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Knuble (Washington, District of Columbia); Jeffrey Piepmeier (Greenbelt, Maryland); Kevin Horgan (Washington, District of Columbia); Jared Lucey (Columbia, Maryland) |
| ABSTRACT | A microwave radiometer with reduced volume, mass, phase noise, and power requirements and increased harmonic rejection, includes a fixed number of frequency banks configured to provide signals within separate, non-overlapping local oscillation frequency bands, a detection circuit configured to detect one or more microwave RF signals, and an RF downconverter configured to mix the signals within the separate, non-overlapping local oscillation frequency bands with the one or more microwave RF signals to provide a continuous range of down converted frequencies. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/371254 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/18 (20130101) H04B 1/0028 (20130101) H04B 1/1615 (20130101) Original (OR) Class H04B 1/1638 (20130101) H04B 7/18515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659991 | Pedersen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Liam Pedersen (San Francisco, California); Maarten Sierhuis (San Francisco, California); Hans Utz (Campbell, California); Mauro Della Penna (San Francisco, California); Terrence Fong (Moffett Field, California); Mark Allan (Campbell, California); Maria Bualat (San Jose, California); Eric Schafer (Kentfield, California) |
| ABSTRACT | Methods, apparatuses, systems, and non-transitory computer readable storage media for providing bandwidth constrained image processing are described. The disclosed technology determines a data transfer rate of at least one signal received from a vehicle, the at least one signal including state/status data of the vehicle. In response to determining that the data transfer rate satisfies a data transfer rate criterion, a location of the vehicle and a location of at least one of a plurality of objects that obstruct the at least one signal is determined using the state data and external data associated with the vehicle. The disclosed technology generates optimized state data using the state data and the external data. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 16/461104 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) G05D 1/0038 (20130101) G05D 2201/0213 (20130101) Image Data Processing or Generation, in General G06T 1/0007 (20130101) G06T 3/40 (20130101) G06T 5/002 (20130101) G06T 5/008 (20130101) G06T 2200/16 (20130101) G06T 2207/20104 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0894 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 4/029 (20180201) H04W 28/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10656293 | Griffin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sean Robert Griffin (Slidell, Louisiana); Bradley Bruce Lingsch (Diamondhead, Mississippi) |
| ASSIGNEE(S) | Proteus Technologies (Slidell, Louisiana) |
| INVENTOR(S) | Sean Robert Griffin (Slidell, Louisiana); Bradley Bruce Lingsch (Diamondhead, Mississippi) |
| ABSTRACT | This invention provides a system apparatus and method for ship-towed deployment of a non-linear volumetric array of hydrophones, allowing line-intersect or line-transect sampling of marine mammal populations through passive acoustic monitoring, enabling unambiguous real-time three-dimensional localization of single sounds received through a low-cost, modular, robust, stable, small, light, neutrally to slightly negatively buoyant volumetric array having low self-noise and low flow noise, that avoids putting high tension on the tow cable and that is compatible with standard hydrophones, instrumentation, cabling, and analytical software. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/238806 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/18 (20130101) G01S 5/22 (20130101) G01S 19/13 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657378 | Bovik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Alan Bovik (Austin, Texas); Todd Goodall (Austin, Texas) |
| ABSTRACT | A method, system and computer program product for classifying an image or video. An image or video to be classified is received. Scene statistics (statistical model of pictures, images or videos representative of pictures, images or videos, respectively, that are captured of the physical world) of the image or video are captured. A model (a statistical model that describes a set of probability distributions) of the image or video is then created using the captured scene statistics. A comparison between the model of the image or video with two other models of images or videos is performed, such as a model of visible light images or videos and a model of infrared images or videos. The received image or video is then classified (e.g., classified as corresponding to a visible light image) based on the comparison. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/754249 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00684 (20130101) G06K 9/00718 (20130101) Original (OR) Class G06K 9/00744 (20130101) G06K 9/00771 (20130101) G06K 9/6212 (20130101) G06K 9/6277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10655132 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Weijuan Yang (Miami, Florida); Haixiang Yu (Miami, Florida); Yingzhu Liu (Miami, Florida); Yi Xiao (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Weijuan Yang (Miami, Florida); Haixiang Yu (Miami, Florida); Yingzhu Liu (Miami, Florida); Yi Xiao (Miami, Florida) |
| ABSTRACT | The subject invention provides a novel SELEX strategy for isolating cross-reactive aptamers that recognize a core structure of a small-molecule family and bind to each structurally-similar molecule in said family. The subject invention also provides methods, assays, and products for detecting small-molecule targets of the family in a sample in both clinical and field settings. Such method is based on an aptamer sensor that reports the presence of small-molecule targets via a sensitive colorimetric signal for naked-eye detection. The subject invention further provides exonuclease-based methods for generating structure-switching aptamers from fully folded aptamers and developing electrochemical aptamer-based (E-AB) sensors for rapid and sensitive detection of synthetic cathinones. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/174764 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/167 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10657413 | Kalivas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IDAHO STATE UNIVERSITY (Pocatello, Idaho) |
| ASSIGNEE(S) | Idaho State University (Idaho Falls, Idaho) |
| INVENTOR(S) | John Kalivas (Pocatello, Idaho); Rene Rodriguez (Pocatello, Idaho); Ikwulono David Unobe (Pocatello, Idaho); Lisa Lau (Idaho Falls, Idaho) |
| ABSTRACT | Methods for identifying marks in a defaced metal surface by use of computer-implemented processing of images obtained according to a thermal lock-in imaging technique are described. Methods include processing phase images and/or amplitude images according to principal component analysis of a concatenated input matrix and development of a score image for each principal component determined by the analysis. Score images or extracted features of score images (e.g., Zernike moments) are compared to images/features in a reference data library and based upon the comparison, the defaced mark can be identified. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/365832 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/623 (20130101) G06K 9/6202 (20130101) G06K 9/6215 (20130101) Original (OR) Class G06K 9/6247 (20130101) G06K 9/6288 (20130101) Image Data Processing or Generation, in General G06T 7/001 (20130101) G06T 2207/10048 (20130101) G06T 2207/30136 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10654610 | Lee, Sr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | James Edward Lee, Sr. (St. Leonard, Maryland) |
| ABSTRACT | Embodiments of a reusable stackable shipping box are provided herein. The reusable stackable shipping box may be reused and cleaned without causing harm to the integrity of the box. In addition, the box is slightly tapered in shape such that the box may be stacked upon and within other boxes for ease in shipping and organization. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 16/421336 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 5/001 (20130101) Original (OR) Class B65D 5/10 (20130101) B65D 5/14 (20130101) B65D 5/0245 (20130101) B65D 5/0281 (20130101) B65D 5/4266 (20130101) B65D 5/4608 (20130101) B65D 5/48024 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/807 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10659413 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leo J. Campbell (Arlington, Virginia); Jon L. Cook (Alexandria, Virginia); Wayne H. Orbke (Germantown, Tennessee); Christine Ray (Washington, District of Columbia); Cathy M. Rogerson (Annandale, Virginia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Leo J. Campbell (Arlington, Virginia); Jon L. Cook (Alexandria, Virginia); Wayne H. Orbke (Germantown, Tennessee); Christine Ray (Washington, District of Columbia); Cathy M. Rogerson (Annandale, Virginia) |
| ABSTRACT | An electronic account is provided to a customer to enable the customer to access electronic services, such as e-mail and electronic transactions. The electronic account links an electronic address of the customer to a physical address of the customer. Using the electronic account, electronic services can be provided to the customer at either the electronic or physical address, or both. The services can be both secure and non-secure and can be provided by any service provider, such as an online merchant, a government agency, or a bank. |
| FILED | Monday, March 25, 2013 |
| APPL NO | 13/849851 |
| ART UNIT | 2458 — Computer Networks |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/107 (20130101) G06Q 20/04 (20130101) G06Q 20/10 (20130101) G06Q 20/14 (20130101) G06Q 20/40 (20130101) G06Q 20/102 (20130101) G06Q 20/401 (20130101) G06Q 20/3674 (20130101) G06Q 20/3821 (20130101) G06Q 20/4012 (20130101) G06Q 30/0601 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/06 (20130101) H04L 51/14 (20130101) H04L 51/20 (20130101) Original (OR) Class H04L 51/28 (20130101) H04L 63/08 (20130101) H04L 63/083 (20130101) H04L 63/102 (20130101) H04L 63/123 (20130101) H04L 63/0823 (20130101) H04L 63/1408 (20130101) H04L 67/306 (20130101) H04L 69/329 (20130101) H04L 2463/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10655135 | Daniell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 14/353980 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) A61K 38/51 (20130101) A61K 38/162 (20130101) A61K 38/164 (20130101) A61K 38/2278 (20130101) Peptides C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10656102 | Regensburger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Joe Regensburger (Grove City, Ohio); Douglas Mooney (Columbus, Ohio); Laura Aume (Circleville, Ohio); Amir Rahimi (Powell, Ohio); Joe Cochran (Egg Harbor Township, New Jersey) |
| ABSTRACT | A method for evaluating system performance can include comparing a test average of instances of variables of test system variables to a baseline average of a baseline variables. Each of the instances of the variable of the test system variables may be shifted by a shift amount for a subset of the variables. A modified test data set may be generated from the shifted test data set. The modified test data set may be transformed with a sparse principal component analysis into test components. The test components may be compared to baseline components using a Hotelling T2 as a test statistic. Performance of the system may be quantified based upon the test statistic. |
| FILED | Thursday, October 22, 2015 |
| APPL NO | 14/919957 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) Original (OR) Class G01N 2223/302 (20130101) G01N 2223/419 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6247 (20130101) G06K 9/6249 (20130101) G06K 9/6265 (20130101) G06K 2209/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10655104 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | R. Lane Smith (Palo Alto, California); Dennis R. Carter (Stanford, California); David J. Schurman (Stanford, California) |
| ABSTRACT | A method for in vivo, ex vivo and in vitro regeneration of cartilage and collagen. In vivo, ex vivo and in vitro regeneration and de novo formation of articular cartilage and collagen by intermittently applied hydrostatic pressure. The application of external interval loading consisting of repeated periods of applied hydrostatic pressure followed and interrupted by periods of recovery. The application of the intermittent hydrostatic pressure at physiological levels 5-10 MPA for an interval of 4 hours followed by a recovery period up to about 20 hours, said pressure applied to the cartilage cells in vitro, explants of cartilage ex vivo and in vivo to cartilage that remains intact within to joint space of diarthrotic joints. The interval loading results in the selective inhibition of matrix degrading enzymes, pro-inflammatory cytokines and chemokines that attract inflammatory cells into the joint cavity and in selective decrease of gene expression of growth factors that are inhibitory to type II collagen expression. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 14/553869 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) A61F 2/28 (20130101) A61F 2/3094 (20130101) A61F 2/30756 (20130101) A61F 2240/001 (20130101) A61F 2310/00365 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2521/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10655870 | Lowenstein |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AIL RESEARCH INC. (Princeton Junction, New Jersey) |
| ASSIGNEE(S) | AIL RESEARCH, INC. (Hopewell, New Jersey) |
| INVENTOR(S) | Andrew Lowenstein (Princeton Junction, New Jersey) |
| ABSTRACT | A device for cooling and dehumidifying a first stream of air includes a first heat exchanger that cools the first stream of air from a first temperature to a lower second temperature, an absorber, a regenerator and one or more pumps and conduits. The device operates under conditions where liquid desiccant removes moisture from the first stream of air in the absorber and the second temperature of the first stream of air that leaves the first heat exchanger is lower than the temperature of the liquid desiccant supplied to the absorber. |
| FILED | Friday, October 24, 2014 |
| APPL NO | 15/504528 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 3/1429 (20130101) F24F 2003/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10658091 | Kandel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Hom Kandel (Tallahassee, Florida); Jun Lu (Tallahassee, Florida) |
| ABSTRACT | A coating mixture comprising at least one ceramic powder and a first and second binder that when applied to a substrate and heat treated produces a thin ceramic electrical insulation coating suitable for superconducting magnet applications. |
| FILED | Monday, July 14, 2014 |
| APPL NO | 14/330326 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/0254 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/46 (20130101) H01B 3/447 (20130101) H01B 3/448 (20130101) Original (OR) Class H01B 12/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10653691 | Tesar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Paul J. Tesar (Wickliffe, Ohio); Fadi J. Najm (Cleveland, Ohio); Robert H. Miller (Cleveland, Ohio) |
| ABSTRACT | A method of promoting remyelination in a subject in need thereof includes administering to the subject a therapeutically effective amount of at least one (1,3) Diazole compound, wherein the therapeutically effective amount is the amount effective to induce endogenous oligodendrocyte precursor cell (OPC) differentiation in the subject's central nervous system. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230576 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/573 (20130101) A61K 31/4174 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10653769 | Pushko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEDIGEN, INC. (Frederick, Maryland) |
| ASSIGNEE(S) | MEDIGEN, INC. (Frederick, Maryland) |
| INVENTOR(S) | Peter Pushko (Frederick, Maryland); Igor Lukashevich (Cockeysville, Maryland) |
| ABSTRACT | Described herein are iDNA vectors and vaccines and methods for using the same. The iDNA generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses, particularly yellow fever virus and Venezuelan equine encephalitis virus. When iDNA is injected into the vaccine recipient, RNA of live attenuated virus is generated by in vivo transcription in the recipient's tissues. This initiates production of progeny attenuated viruses in the tissues of the vaccine recipient, as well as elicitation of an effective immune response protecting against wild-type, non-attenuated virus. |
| FILED | Thursday, April 19, 2018 |
| APPL NO | 15/957550 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/193 (20130101) Original (OR) Class A61K 2039/53 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 2770/24134 (20130101) C12N 2770/24161 (20130101) C12N 2770/36134 (20130101) C12N 2770/36161 (20130101) Technologies for Adaptation to Climate Change Y02A 50/388 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10656235 | Bowden |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | James M. Bowden (Forney, Texas) |
| ABSTRACT | The concepts, systems and method described herein provide direction finding (DF) methods based on a minimum distance (MINDIST) search to principal components. In an embodiment, the method includes capturing samples of data from one or more array elements. The samples may be samples of a signal received at the array elements. The method includes generating a spatial sample covariance matrix (SCM) using the samples of data, extracting principal components from the SCM and generating a principal component table using angle and frequency measurement for each of the principal components. The method further includes determining a distance between a test point and each value in the principal component table and identifying a minimum distance point corresponding to a direction of the received signal. The minimum distance point may correspond to direction of arrival of a signal on the one or more array elements. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267564 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/48 (20130101) Original (OR) Class G01S 3/465 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 19, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200519.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page