FedInvent™ Patents
Patent Details for Tuesday, May 26, 2020
This page was updated on Monday, March 27, 2023 at 06:05 AM GMT
Department of Health and Human Services (HHS)
US 10660519 | Carrasco-Zevallos et al. |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Oscar M. Carrasco-Zevallos (Durham, North Carolina); Joseph A. Izatt (Durham, North Carolina); Christian B. Viehland (Durham, North Carolina); Ryan McNabb (Durham, North Carolina) |
ABSTRACT | Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography (OCT) are disclosed. According to an aspect, an imaging system includes an eye tracking device configured to determine movement of an eye. The imaging system also includes an OCT apparatus configured to generate OCT images of a retina of the eye. The OCT apparatus includes a scanner operable to be moved for relocating an OCT scan pivot at a pupil plane for image capture and during capture of the OCT images. The imaging system also includes a controller configured to control the scanner to relocate the OCT scan pivot at the pupil plane based on the determined movement of the eye. |
FILED | Friday, January 30, 2015 |
APPL NO | 15/113800 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 3/113 (20130101) A61B 3/117 (20130101) A61B 3/152 (20130101) Original (OR) Class A61B 3/1225 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660541 | Ernst et al. |
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APPLICANT(S) | The University of Hawai'i (Honolulu, Hawaii); The Queen's Medical Center (Honolulu, Hawaii) |
ASSIGNEE(S) | The University of Hawai'i (Honolulu, Hawaii); The Queen's Medical Center (Honolulu, Hawaii) |
INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Brian Keating (Chicago, Illinois); Aditya Singh (Honolulu, Hawaii); Maxim Zaitsev (Freiburg, Germany); Michael Herbst (Freiburg, Germany) |
ABSTRACT | The systems, methods, and devices described herein generally relate to achieving accurate and robust motion correction by detecting and accounting for false movements in motion correction systems used in conjunction with medical imaging and/or therapeutic systems. In other words, in some embodiments of the systems, methods, and devices described herein can be configured to detect false movements for motion correction during a medical imaging scan and/or therapeutic procedure, and thereby ensure that such false movements are not accounted for in the motion correction process. Upon detection of false movements, the imaging or therapeutic system can be configured to transiently suppress and/or subsequently repeat acquisitions. |
FILED | Tuesday, March 13, 2018 |
APPL NO | 15/920020 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/682 (20130101) A61B 5/1121 (20130101) A61B 5/1127 (20130101) A61B 5/7207 (20130101) A61B 5/7267 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/629 (20130101) G06K 9/6256 (20130101) G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/246 (20170101) G06T 7/248 (20170101) G06T 2207/10016 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30004 (20130101) G06T 2207/30204 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660550 | Lucisano et al. |
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APPLICANT(S) | GLYSENS INCORPORATED (San Diego, California) |
ASSIGNEE(S) | GLYSENS INCORPORATED (San Diego, California) |
INVENTOR(S) | Joseph Lucisano (San Diego, California); Jonathan Wilensky (San Diego, California); Robert Engler (Del Mar, California) |
ABSTRACT | Implantable sensor apparatus and methods of implantation. In one embodiment, a fully implantable, biocompatible sensor is disposed within a cavity or pocket formed within a living being, such that the sensor remains in a desired orientation and placement so as to enhance the performance of the sensor, and mitigate the effects of one or more factors potentially deleterious to the operation of the sensor and the host being. In one implementation, the sensor comprises an implantable biocompatible oxygen-based glucose sensor which is implanted deep within the being's torso tissue proximate the extant fascia, and oriented such that an active detector aspect of the device faces away from the being's skin surface. In one variant, the deep placement, orientation, and construction of the sensor itself cooperate to enhance the performance of the sensor, especially over extended periods of time, with little need for external calibration. |
FILED | Tuesday, December 29, 2015 |
APPL NO | 14/982346 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0015 (20130101) A61B 5/0031 (20130101) A61B 5/72 (20130101) A61B 5/14503 (20130101) Original (OR) Class A61B 5/14532 (20130101) A61B 5/14542 (20130101) A61B 17/32093 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14 (20130101) A61M 5/1723 (20130101) A61M 2210/1021 (20130101) A61M 2230/005 (20130101) A61M 2230/201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660621 | Markowitz et al. |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); Amitabh Chak (University Heights, Ohio); Joseph Willis (Shaker Heights, Ohio); Jeffrey Silver Taggart (Cleveland Heights, Ohio); Rebecca Blice (Akron, Ohio); Dean Secrest (Concord Township, Ohio); Dennis Siedlak (Willoughby Hills, Ohio) |
ABSTRACT | A device for collecting a biological sample in a patient includes a collection portion having a first axial end portion and a second axial end portion. The second axial end portion has a collapsed position and an expanded position. The second axial end portion moves in an axial direction relative to the first axial end portion when the second axial end portion moves between the collapsed position and the expanded position. The second axial end portion extends axially into the first axial end portion and has a concave shape when in the collapsed position. The second axial end portion is convex when in the expanded position. |
FILED | Friday, December 12, 2014 |
APPL NO | 15/103638 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Original (OR) Class A61B 2010/0216 (20130101) A61B 2010/0225 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660754 | Sierad et al. |
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APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
INVENTOR(S) | Leslie Sierad (Central, South Carolina); Richard Pascal, III (Chapin, South Carolina); Chris deBorde (Longwood, Florida); Dan Simionescu (Pendleton, South Carolina); Agneta Simionescu (Pendleton, South Carolina) |
ABSTRACT | Tissue holders that can be used for gripping natural or synthetic heart valves are described. The tissue holder can include a clamping mechanism and a spring and can be self-adjusting with regard to pressure applied to the tissue gripped in the holder. The tissue holder can be removably attached to systems for processing the tissues and can provide completely hands-free processing of a tissue from development or excisement to implantation and/or completion of testing. |
FILED | Monday, June 18, 2018 |
APPL NO | 16/010889 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2472 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660828 | Deng et al. |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Yang Deng (Edison, New Jersey); Asiri Ediriwickrema (Cary, North Carolina); William M. Saltzman (New Haven, Connecticut) |
ABSTRACT | Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins. |
FILED | Monday, September 19, 2016 |
APPL NO | 15/269456 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/90 (20130101) A61K 8/0241 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) A61K 2800/412 (20130101) A61K 2800/413 (20130101) A61K 2800/624 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) Acyclic or Carbocyclic Compounds C07C 59/06 (20130101) C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660860 | Gong et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Shaoqin Gong (Middleton, Wisconsin); Wei Xu (Middleton, Wisconsin); Yuyuan Wang (Madison, Wisconsin); Fabao Liu (Madison, Wisconsin) |
ABSTRACT | Provided herein are peptides comprising an amino acid sequence having at least about 85% sequence identity to RYRPRAPIIAVT (SEQ ID NO: 1). These cationic peptides inhibit PKM2 methylation and may be used in the treatment of breast cancer and other diseases or conditions in which PKM2 is overexpressed. Such PKM2 peptides may be delivered to cancer cells using pH sensitive unimolecular nanoparticles comprising anionic polymers. |
FILED | Thursday, February 08, 2018 |
APPL NO | 15/892140 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/513 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 38/005 (20130101) A61K 38/10 (20130101) A61K 47/60 (20170801) A61K 47/595 (20170801) Peptides C07K 7/08 (20130101) C07K 17/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660861 | Hanes et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Justin Hanes (Baltimore, Maryland); Barbara S. Slusher (Kingsville, Maryland); Anne Le (Baltimore, Maryland); Jie Fu (Baltimore, Maryland); Qingguo Xu (Baltimore, Maryland) |
ABSTRACT | Currently available glutaminase inhibitors are generally poorly soluble, metabolically unstable, and/or require high doses, which together reduce their efficacy and therapeutic index. These can be formulated into nanoparticles and delivered safely and effectively for treatment of pancreatic cancer and other glutamine addicted cancers. Studies demonstrate that nanoparticle delivery of BPTES, relative to use of BPTES alone, can be safely administered and provides dramatically improved tumor drug exposure, resulting in greater efficacy. GLS inhibitors can be administered in higher concentrations with sub-100 nm nanoparticles, since the nanoparticles package the drug into “soluble” colloidal nanoparticles, and the nanoparticles deliver higher drug exposure selectively to the tumors due to the enhanced permeability and retention (EPR) effect. These factors result in sustained drug levels above the IC50 within the tumors for days, providing significantly enhanced efficacy compared to unencapsulated drug. |
FILED | Wednesday, July 08, 2015 |
APPL NO | 15/324835 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 285/135 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660873 | Kolliputi et al. |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Narasaiah Kolliputi (Tampa, Florida); Richard F. Lockey (Tampa, Florida); Lakshmi Galam (Tampa, Florida) |
ABSTRACT | Methods of treating or preventing allergic or pulmonary diseases characterized by endothelial dysfunction with Alda-1 are presented. Treatment of pulmonary endothelial cells subjected to hyperoxia with Alda-1 showed an increase in ALDH2 activity and expression. Treatment with Alda-1 also illustrated a decrease in oxidative stress, a decrease in reactive oxygen species (ROS), a decrease in apoptosis, a decrease in inflammation and an enhancement of mitochondrial membrane potential. |
FILED | Friday, February 22, 2019 |
APPL NO | 16/282966 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 11/16 (20180101) A61P 37/08 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660874 | Bugni et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Timothy Scott Bugni (Madison, Wisconsin); Thomas Philip Wyche (Chelsea, Massachusetts); Douglas R. Braun (Mount Horeb, Wisconsin); Jeffrey S. Piotrowski (Madison, Wisconsin); Nasia Safdar (Madison, Wisconsin) |
ABSTRACT | An isolated or synthesized compound of Formula I and salts thereof are provided. A compound isolated from Actinomadura and having a chemical formula of C38H60O12 is also provided. Compositions including the compounds and methods of using the compounds to treat bacterial infections including gram positive infections such as C. difficile are also disclosed. |
FILED | Wednesday, October 28, 2015 |
APPL NO | 15/522713 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660890 | Gradilone et al. |
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APPLICANT(S) | Sergio A. Gradilone (Rochester, Minnesota); Nicholas F. LaRusso (Rochester, Minnesota) |
ASSIGNEE(S) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR) (Bethesda, Maryland) |
INVENTOR(S) | Sergio A. Gradilone (Rochester, Minnesota); Nicholas F. LaRusso (Rochester, Minnesota) |
ABSTRACT | An HDAC6-specific inhibitor (i.e., a compound of Formula I or II) is shown to reduce the pathogenesis associated with polycystic disease. Administration of an HDAC6-specific inhibitor attenuated many of the symptoms characteristic of polycystic liver disease including cyst formation, cyst growth and cholangiocyte proliferation. Treatment with a HDAC6-specific inhibitor also increased the amount of bile duct acetylated tubulin and β-catenin phosphorylation and/or acetylation while reducing bile duct β-catenin synthesis. These results demonstrate that HDAC6 is overexpressed in cystic cholangiocytes and that its pharmacological inhibition reduces cholangiocyte proliferation and cyst growth. |
FILED | Friday, October 24, 2014 |
APPL NO | 14/523319 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660896 | Strum et al. |
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APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
ASSIGNEE(S) | GI Therapeutics, Inc. (Research Triangle Park, North Carolina) |
INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Apex, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis X. Tavares (Durham, North Carolina) |
ABSTRACT | This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC) as well as renal cells, from damage associated with DNA damaging chemotherapeutic agents. In one aspect, improved protection of healthy cells is disclosed using disclosed compounds that act as highly selective and short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects undergoing DNA damaging chemotherapeutic regimens for the treatment of proliferative disorders. |
FILED | Monday, April 02, 2018 |
APPL NO | 15/943278 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/527 (20130101) Original (OR) Class A61K 31/555 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Heterocyclic Compounds C07D 487/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660909 | Zebala et al. |
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APPLICANT(S) | Syntrix Biosystems Inc. (Auburn, Washington) |
ASSIGNEE(S) | Syntrix Biosystems Inc. (Auburn, Washington) |
INVENTOR(S) | John A. Zebala (Issaquah, Washington); Dean Y. Maeda (Seattle, Washington); Aaron D. Schuler (Auburn, Washington) |
ABSTRACT | What is described is a method for treating cancer in a patient in need of such treatment through the use of an antagonist to CXCR1 and/or CXCR2 receptors by administering a therapeutically effective amount of an antagonist of CXCR1 and/or CXCR2, or pharmaceutical compositions thereof, either alone as monotherapy, or in combination with at least one other anticancer therapy. |
FILED | Friday, February 23, 2018 |
APPL NO | 15/903503 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 33/24 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/572 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660911 | Collins et al. |
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APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | James J. Collins (Newton, Massachusetts); Kyle R. Allison (Flint, Michigan); Mark P. Brynildsen (Pennington, New Jersey) |
ABSTRACT | Provided herein are compositions and methods to improve treatment of chronic infections, and reduce, delay, or inhibit formation of biofilms, using specific combinations of aminoglycoside antibiotics and high, localized concentrations of one or more PMF stimulating compounds. These novel methods are easily adapted to clinical settings as toxicity and efficacy of the antibiotics and metabolites used have already been studied in vivo, and as dosing for both the antibiotics and metabolites are known. These approaches and therapeutic methods are also useful with non-metabolic chemicals that induce proton-motive force in bacteria. |
FILED | Monday, August 27, 2018 |
APPL NO | 16/113482 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/19 (20130101) A61K 31/047 (20130101) A61K 31/7004 (20130101) A61K 31/7004 (20130101) A61K 31/7036 (20130101) Original (OR) Class A61K 31/7036 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660916 | Forman et al. |
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APPLICANT(S) | City of Hope (Duarte, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Stephen J. Forman (Duarte, California); Armen Mardiros (Duarte, California); Christine E. Brown (Duarte, California); Uma Maheswara Rao Jonnalagadda (Troy, Michigan) |
ABSTRACT | A family of chimeric antigen receptors (CARs) containing a CD123 specific scFv was developed to target different epitopes on CD123. In some embodiments, such a CD123 chimeric antigen receptor (CD123CAR) gene includes an anti-CD123 scFv region fused in frame to a modified IgG4 hinge region comprising an S228P substitution, an L235E substitution, and optionally an N297Q substitution; a costimulatory signaling domain; and a T cell receptor (TCR) zeta chain signaling domain. When expressed in healthy donor T cells (CD4/CD8), the CD123CARs redirect T cell specificity and mediated potent effector activity against CD123+ cell lines as well as primary AML patient samples. Further, T cells obtained from patients with active AML can be modified to express CD123CAR genes and are able to lyse autologous AML blasts in vitro. Finally, a single dose of 5.0×106 CAR123 T cells results in significantly delayed leukemic progression in mice. These results suggest that CD123CAR-transduced T cells may be used as an immunotherapy for the treatment of high risk AML. |
FILED | Monday, May 22, 2017 |
APPL NO | 15/601793 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/2866 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660932 | Longo et al. |
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APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Valter D. Longo (Playa del Rey, California); Roberta Buono (Los Angeles, California) |
ABSTRACT | Stem cell-based therapies can potentially reverse organ dysfunction and diseases but the removal of impaired tissue and reactivation of the program leading to organ regeneration pose major challenges. In mice, a four-day fasting mimicking diet (FMD) induces a step-wise expression of Sox17 and Pdx-1, resembling that observed during pancreatic development and followed by Ngn3-driven generation of insulin-producing β-cells. FMD cycles restore insulin secretion and glucose homeostasis in both a type 2 and type 1 diabetes mouse models. In human type 1 diabetes pancreatic islets, fasting conditions reduce PKA and mTOR activity and induce Sox2 and Ngn3 expression and insulin production. The effects of the FMD are reversed by IGF-1 treatment and recapitulated by PKA and mTOR inhibition. These results indicate that a FMD promotes the reprogramming of pancreatic cells to restore insulin generation in islets from T1D patients and reverse both T1D and T2D phenotypes in mouse models. |
FILED | Wednesday, February 15, 2017 |
APPL NO | 15/433906 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/12 (20160801) A23L 33/15 (20160801) A23L 33/16 (20160801) A23L 33/17 (20160801) A23L 33/30 (20160801) A23L 33/40 (20160801) A23L 33/115 (20160801) A23L 33/125 (20160801) A23L 33/155 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/30 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/07 (20130101) A61K 31/07 (20130101) A61K 31/51 (20130101) A61K 31/51 (20130101) A61K 31/70 (20130101) A61K 31/70 (20130101) A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 31/455 (20130101) A61K 31/455 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/525 (20130101) A61K 31/525 (20130101) A61K 31/4188 (20130101) A61K 31/4188 (20130101) A61K 31/4415 (20130101) A61K 31/4415 (20130101) A61K 33/04 (20130101) A61K 33/04 (20130101) A61K 33/06 (20130101) A61K 33/06 (20130101) A61K 33/26 (20130101) A61K 33/26 (20130101) A61K 33/32 (20130101) A61K 33/32 (20130101) A61K 33/34 (20130101) A61K 33/34 (20130101) A61K 38/02 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660933 | Song |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Wenxia Song (Olney, Maryland) |
ABSTRACT | Provided are compositions, methods and devices for prophylaxis and/or therapy of sexually transmitted bacterial infections that infect the female reproductive tract. The compositions methods and devices are used for intravaginal administration of compositions that contain a peptide agent known as PIK and/or a compound known as ML-7. Demonstrations of embodiments are provided for infection models that involve Neisseria gonorrhoeae. |
FILED | Monday, October 31, 2016 |
APPL NO | 15/749548 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 5/0817 (20130101) C07K 5/1008 (20130101) C07K 5/1019 (20130101) C07K 5/06052 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660937 | McLaughlin et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of The Leland Stanford Junio (Palo Alto, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Tracey L. McLaughlin (Stanford, California); Colleen M. Craig (Stanford, California) |
ABSTRACT | Treatment of hyperinsulinemic hypoglycemia comprises administration of an effective amount of glucagon-like peptide-1 receptor antagonist (GLP1RA) exendin(9-39). Patients suffering from hyperinsulinemic hypoglycemia after bariatric surgery or gastrointestinal surgery experience particular benefit, as there is no current method effective for their treatment. Prevention or reduction of acute adverse effects of postprandial hypoglycemia, such as palpitations, tremor, weakness, sweating, confusion, fatigue, blurred vision, seizures, or loss of consciousness, and prevention of chronic adverse effects of hyperinsulinemic hypoglycemia, such as cognitive impairment, can be achieved by treatment with GLP1RA exendin(9-39). |
FILED | Monday, May 23, 2016 |
APPL NO | 15/576646 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 38/17 (20130101) A61K 38/22 (20130101) A61K 38/26 (20130101) A61K 38/2278 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660957 | Strittmatter |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Stephen M. Strittmatter (Guilford, Connecticut) |
ABSTRACT | The present invention provides compositions and methods for treating and preventing an Aβ-modulated disease. In certain embodiments, the invention provides an inhibitor of Fyn tyrosine kinase, and methods of using the same. In certain embodiments, the inhibitor of the invention inhibits Aβ oligomer induced signaling and reduces or halts the progression of Alzheimer's Disease. |
FILED | Thursday, May 08, 2014 |
APPL NO | 14/272874 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 45/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660973 | Sullenger et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Kady-Ann C. Steen-Burrell (Durham, North Carolina); Bethany Powell Gray (Durham, North Carolina) |
ABSTRACT | Provided herein are imaging agents, antidotes to the imaging agents and methods of using the same to image a thrombus or blood clot or thrombin including sites of thrombin accumulation and to diagnose and treat thrombosis. The imaging agents include an aptamer capable of binding the thrombus or thrombin in particular linked to a reporter moiety. The imaging agents may be used to label the thrombus or sites of thrombin accumulation. Antidotes capable of binding to the aptamer in the imaging agent are also provided. The antidotes may further be linked to a quencher capable of quenching the reporter moiety. |
FILED | Thursday, April 28, 2016 |
APPL NO | 15/570065 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) Original (OR) Class A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/113 (20130101) C12N 2310/317 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/3517 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660976 | Sharma |
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FUNDED BY |
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APPLICANT(S) | Vijay Sharma (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Vijay Sharma (St. Louis, Missouri) |
ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions and methods for imaging and treating subjects with amyloidosis or multiple myeloma with or without amyloidosis. |
FILED | Tuesday, November 06, 2018 |
APPL NO | 16/181628 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) Original (OR) Class A61K 51/0455 (20130101) A61K 51/1244 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/587 (20130101) G01N 33/6896 (20130101) G01N 2333/4709 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660979 | Yarmush et al. |
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FUNDED BY |
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APPLICANT(S) | Martin L. Yarmush (Boston, Massachusetts); William G. Austen (Weston, Massachusetts); Alexander Golberg (Boston, Massachusetts); Saiqa L. Khan (Agawam, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Martin L. Yarmush (Boston, Massachusetts); William G. Austen (Weston, Massachusetts); Alexander Golberg (Boston, Massachusetts); Saiqa L. Khan (Agawam, Massachusetts) |
ABSTRACT | A system and method for controlling microbial growth on and in medical devices and implants, especially biofilm infections, involves using pulsed electric fields (PEF). To eradicate at least a portion of a biofilm on a medical implant, for example, 1500 volts can be applied through an electrode system, with pulse duration of 50 μs and pulse delivery frequency of 2 Hz. In the clinical setting, systemic microbial therapy can be combined with PEF to achieve a synergistic effect leading to improved eradication of infections. |
FILED | Thursday, August 25, 2016 |
APPL NO | 15/754439 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/00 (20130101) A61B 18/14 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/03 (20130101) Original (OR) Class A61L 2202/24 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2025/0019 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661033 | Yeates et al. |
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FUNDED BY |
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APPLICANT(S) | KAER BIOTHERAPEUTICS CORPORATION (Escondido, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Donovan B Yeates (Escondido, California); Xin Heng (McKinney, Texas) |
ABSTRACT | A nozzle and a method of generating an inhalable aerosol from a liquid solution or liquid suspension and a gas by operating the nozzle. A column-like aerosol plume is generated having fluid particles within a particle free sheath of gas, the aerosol plume being generated from a compressed gas interacting within the aerosolizing space with a fluid ejected along the central axis, and generates a Venturi effect entraining gas that flows over the convex outer nozzle surface that together with the particle free sheath keeps the circumferential edge and the outer nozzle surface free of particle deposition. An aerosol exit orifice diameter is at least 1.3 times larger than the fluid exit orifice diameter; and a converging annular pressurized gas channel extending at an acute gas flow angle of 10-30° with respect to a central axis. |
FILED | Monday, February 06, 2017 |
APPL NO | 15/425529 |
ART UNIT | 3752 — Fluid Handling and Dispensing |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/001 (20140204) A61M 11/06 (20130101) Original (OR) Class A61M 2202/064 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/02 (20130101) B05B 7/10 (20130101) B05B 7/12 (20130101) B05B 7/068 (20130101) B05B 7/0475 (20130101) B05B 7/0483 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661091 | Guerin et al. |
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FUNDED BY |
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APPLICANT(S) | Bastien Guerin (Cambridge, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts); Bruce Rosen (Lexington, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Bastien Guerin (Cambridge, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts); Bruce Rosen (Lexington, Massachusetts) |
ABSTRACT | Systems and methods for designing parallel transmission radiofrequency (RF) pulses for use in a RF treatment. The methods include selecting a target region in a subject, and providing a plurality of specific absorption rate (SAR) matrices for estimation of SAR at locations within the subject. The methods also include determining a first set of SAR matrices for locations in the target region using the provided SAR matrices, and determining a second set of SAR matrices for locations not in the target region using the provided SAR matrices. The methods further include designing a plurality of RF pulses for achieving a target power deposition in the target region by using the first set of SAR matrices and the second set of SAR matrices in an optimization that determines a set of RF waveforms that produce a target average local SAR using the first set of SAR matrices while minimizing a local SAR and a global SAR using the second set of SAR matrices. |
FILED | Wednesday, March 25, 2015 |
APPL NO | 14/668393 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) A61B 2034/101 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/403 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/48 (20130101) G01R 33/5612 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662159 | Makriyannis et al. |
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FUNDED BY |
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APPLICANT(S) | MAKScientific, LLC (Burlington, Massachusetts) |
ASSIGNEE(S) | MAKSCIENTIFIC, LLC (Burlington, Massachusetts) |
INVENTOR(S) | Alexandros Makriyannis (Watertown, Massachusetts); Michael Malamas (Jamison, Pennsylvania); Manjunath Lamani (Medford, Massachusetts); Shrouq I. Farah (Everett, Massachusetts) |
ABSTRACT | Provided herein are compounds and pharmaceutical compositions for selectively inhibiting serine hydrolase a/b-hydrolase domain 6 (ABHD6) and dually inhibiting ABHD6 and monoacylglycerol lipase (MGL). The compounds and pharmaceutical compositions disclosed herein are useful for treating a number of therapeutic conditions related to cannabinergic receptor function such as pain, inflammation, neuropathy, neurodegenerative diseases, anxiety disorders, motor function disorder, metabolic disorder, glaucoma and chemotherapy-induced nausea and vomiting and cancer. |
FILED | Wednesday, November 21, 2018 |
APPL NO | 16/198261 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 205/12 (20130101) C07D 209/44 (20130101) C07D 217/04 (20130101) Original (OR) Class C07D 217/06 (20130101) C07D 223/16 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662161 | David et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Sunil Abraham David (St. Paul, Minnesota); Mallesh Beesu (Telangana, India) |
ABSTRACT | The various examples presented herein are directed to compounds of the Formula: wherein R1-R5 are defined herein, and uses of such compounds to, among other things, inhibit an immune response in a subject. |
FILED | Thursday, January 25, 2018 |
APPL NO | 15/879826 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/48 (20130101) Original (OR) Class C07D 239/49 (20130101) C07D 239/50 (20130101) C07D 403/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662164 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
INVENTOR(S) | Mayland Chang (Granger, Indiana); Shahriar Mobashery (Granger, Indiana); Edward Spink (Bollington, United Kingdom); Derong Ding (Mishawaka, Indiana); Sebastian Testero (Rosario, Argentina); Erika Leemans (Hamme, Belgium); Marc Boudreau (Durham, New Hampshire) |
ABSTRACT | The invention provides a newly discovered oxadiazole class of antibiotics. The oxadiazoles impair cell-wall biosynthesis and exhibit activities against the Gram-positive bacteria such as the bacterium Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA) and vancomycin-resistant and linezolid-resistant S. aureus. For example, 5-(1H-indol-5-yl)-3-(4-(4-(trifluoromethyl)phenoxy)phenyl)-1,2,4-oxadiazole (antibiotic 75b) was efficacious in a mouse model of MRSA infection, exhibiting a long half-life, a high volume of distribution, and low clearance. Antibiotic 75b antibiotic is bactericidal and is orally bioavailable. This class of antibiotics can be used as a therapeutic agent against infections by Gram-positive bacteria such as MRSA. |
FILED | Friday, September 25, 2015 |
APPL NO | 15/513892 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 271/06 (20130101) C07D 271/107 (20130101) Original (OR) Class C07D 413/04 (20130101) C07D 471/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65318 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662176 | Watts et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Val J. Watts (West Lafayette, Indiana); Richard M. van Rijn (West Lafayette, Indiana); Daniel P. Flaherty (West Lafayette, Indiana); Jatinder Kaur (West Lafayette, Indiana) |
ABSTRACT | The present invention relates to a method of treatment for chronic pain, opioid dependence, alcohol use disorder or autism using a class of pyrimidinone compounds, an adenylyl cyclase 1 (AC1) inhibitor. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using those compounds disclosed herein. |
FILED | Wednesday, July 18, 2018 |
APPL NO | 16/038236 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/32 (20180101) A61P 25/36 (20180101) Heterocyclic Compounds C07D 403/04 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 409/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662180 | Lawrence et al. |
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FUNDED BY |
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APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | Harshani R. Lawrence (Tampa, Florida); Said M. Sebti (Tampa, Florida); Sevil Ozcan (Lutz, Florida) |
ABSTRACT | Focused library synthesis and medicinal chemistry on an oxadiazole-isopropylamide core proteasome inhibitor provided the lead compound that strongly inhibits CT-L activity. Structure activity relationship studies indicate the amide moiety and two phenyl rings are sensitive toward synthetic modifications. Only para-substitution in the A-ring was important to maintain potent CT-L inhibitory activity. Hydrophobic residues in the A-ring's para-position and meta-pyridyl group at the B-ring significantly improved inhibition. The meta-pyridyl moiety improved cell permeability. The length of the aliphatic chain at the para position of the A-ring is critical with propyl yielding the most potent inhibitor, whereas shorter (i.e. ethyl, methyl or hydrogen) or longer (i.e. butyl, propyl and hexyl) chains demonstrating progressively less potency. Introduction of a stereogenic center next to the ether moiety (i.e. substitution of one of the hydrogens by methyl) demonstrated chiral discrimination in proteasome CT-L activity inhibition (the S-enantiomer was 35-40 fold more potent than the R-enantiomer). |
FILED | Monday, January 29, 2018 |
APPL NO | 15/882094 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 271/04 (20130101) C07D 271/06 (20130101) C07D 413/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662183 | Larsen et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
INVENTOR(S) | Scott D. Larsen (South Lyon, Michigan); Richard Neubig (East Lansing, Michigan); Andrew Haak (Rochester, Minnesota); Kim Hutchings (Dexter, Michigan); Walajapet Rajeswaran (Canton, Michigan); Dinesh Khanna (Ann Arbor, Michigan); Erika Mathes Lisabeth (Howell, Michigan) |
ABSTRACT | Disclosed herein are inhibitors of gene transcription mediated by myocardin-related transcription factor and serum response factor, or both myocardin-related transcription factor and serum response factor (“MRTF/SRF”), and methods for their use in treating or preventing cancer and fibrosis. In particular, disclosed herein are compounds of Formula (I) and Formula (II), and pharmaceutically acceptable salts thereof: wherein the substituents are as described. |
FILED | Friday, November 06, 2015 |
APPL NO | 14/934769 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 211/60 (20130101) C07D 401/06 (20130101) C07D 401/10 (20130101) C07D 405/06 (20130101) C07D 405/10 (20130101) C07D 405/14 (20130101) C07D 409/10 (20130101) C07D 413/06 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 417/10 (20130101) C07D 417/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662191 | Horenstein et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (Gainesville, Florida) |
INVENTOR(S) | Nicole Alana Horenstein (High Springs, Florida); Roger Lee Papke (Gainesville, Florida); Marta Quadri (Vigano, Italy) |
ABSTRACT | Derivatives of N,N-diethyl-N′-phenyl-piperazine, a silent agonist of the mammalian α7 nicotinic acetylcholine receptor, are provided. These silent agonists control the desensitization state of the receptor. Further provided are pharmaceutical compositions that allow the administration of the silent agonists of the disclosure to a subject animal or human in need of treatment for a pathological condition arising from such as inflammation. The novel silent agonists also may be co-administered to a patient simultaneously or consecutively with a type II positive allosteric modulator to modulate the activity of the receptor. |
FILED | Friday, October 14, 2016 |
APPL NO | 15/768175 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/42 (20130101) A61K 31/452 (20130101) A61K 31/452 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/499 (20130101) A61K 31/499 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 211/58 (20130101) C07D 211/70 (20130101) C07D 295/037 (20130101) C07D 295/073 (20130101) C07D 295/096 (20130101) C07D 295/155 (20130101) C07D 471/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662210 | Lippard et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Stephen J. Lippard (Washington, District of Columbia); Kogularamanan Suntharalingam (Boston, Massachusetts) |
ABSTRACT | Compositions and methods comprising osmium are provided. In some embodiments, the osmium compounds comprise a bidentate ligand. In some embodiments, the osmium compounds are used in method for treating cancer. |
FILED | Tuesday, March 26, 2019 |
APPL NO | 16/365561 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0026 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662215 | Renslo et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Adam R. Renslo (Oakland, California); Erica M. W. Lauterwasser (Wachenheim, Germany); Shaun D. Fontaine (Walnut Creek, California); Benjamin B. Spangler (San Francisco, California); James A. Wells (Burlingame, California) |
ABSTRACT | Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier. |
FILED | Tuesday, March 26, 2019 |
APPL NO | 16/364577 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) A61K 31/404 (20130101) A61K 31/427 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/513 (20130101) A61K 31/662 (20130101) A61K 31/4025 (20130101) A61K 31/4192 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/4985 (20130101) A61K 31/7072 (20130101) A61K 31/7076 (20130101) A61K 31/7135 (20130101) A61K 47/64 (20170801) A61K 47/6803 (20170801) A61K 51/0459 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 323/02 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 407/12 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/14 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101) C07D 491/113 (20130101) C07D 491/153 (20130101) C07D 493/04 (20130101) C07D 493/14 (20130101) C07D 519/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) C07F 9/65517 (20130101) C07F 9/65586 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 19/16 (20130101) Original (OR) Class C07H 19/167 (20130101) Peptides C07K 7/06 (20130101) Technologies for Adaptation to Climate Change Y02A 50/411 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662219 | Talley |
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FUNDED BY |
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APPLICANT(S) | EMMYON, INC. (Coralville, Iowa) |
ASSIGNEE(S) | EMMYON, INC. (Coralville, Iowa) |
INVENTOR(S) | John J Talley (St. Louis, Missouri) |
ABSTRACT | Compounds of formula I are disclosed. The compounds are useful for promoting skeletal muscle hypertrophy or treating skeletal muscle atrophy. |
FILED | Friday, October 28, 2016 |
APPL NO | 15/769428 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 21/06 (20180101) Heterocyclic Compounds C07D 307/77 (20130101) Steroids C07J 71/0005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662220 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Jun Liu (Baltimore, Maryland); Jingxin Wang (Baltimore, Maryland); Zufeng Guo (Baltimore, Maryland); Sam Hong (Baltimore, Maryland); Wukun Liu (Baltimore, Maryland); Hanjing Peng (Baltimore, Maryland); Manisha Das (Baltimore, Maryland) |
ABSTRACT | A Rapafucin library containing compounds of the general structure, (A) and (E), and a synthesis of these compounds are provided. |
FILED | Friday, February 03, 2017 |
APPL NO | 16/074017 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 1/047 (20130101) Original (OR) Class C07K 5/10 (20130101) C07K 17/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6803 (20130101) G01N 2500/00 (20130101) G01N 2570/00 (20130101) G01N 2800/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662226 | Nowick et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of Caiifomia (Oakland, California) |
INVENTOR(S) | James S. Nowick (Irvine, California); Adam G. Kreutzer (Irvine, California); Ryan K. Spencer (Ripon, California); Patrick J. Salveson (Irvine, California) |
ABSTRACT | Synthetic Aβ peptides, oligomers, their methods of synthesis, and their applications are provided. The Aβ peptides can form stable, soluble oligomers important for the advancement of knowledge, detection, and treatment of Alzheimer's disease. Antibodies specific to oligomeric Aβ and their methods of synthesis are also described. |
FILED | Thursday, October 26, 2017 |
APPL NO | 15/794776 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 1/22 (20130101) C07K 14/001 (20130101) Original (OR) Class C07K 14/4711 (20130101) C07K 16/18 (20130101) C07K 2317/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662238 | Bok et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (Buenos Aires, Argentina) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Instituto Nacional De Technologia Agropecuaria (Buenos Aires, Argentina) |
INVENTOR(S) | Karin Bok (Bethesda, Maryland); Lorena Laura Garaicoechea (Buenos Aires, Argentina); Viviana Parreno (Buenos Aires, Argentina); Andrea Pamela Aguilar (Buenos Aires, Argentina); Marina Bok (Buenos Aires, Argentina); Lisbeth Kim Green (Olney, Maryland); Stanislav Vladimirovich Sosnovtsev (North Potomac, Maryland) |
ABSTRACT | Isolated VHH monoclonal antibodies are disclosed that specifically bind to a Norovirus polypeptide. In some embodiments, the Norovirus is a Genogroup I Norovirus or a Genogroup II Norovirus. In other embodiments, the Norovirus is Norwalk or MD2004 virus. In some embodiments, the monoclonal antibodies specifically bind VP1. Also disclosed are compositions including the disclosed antibodies, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of a Norovirus in a biological sample, or detecting a Norovirus infection. Also disclosed are methods of treating and/or preventing a NoV infection. |
FILED | Thursday, May 17, 2018 |
APPL NO | 15/982998 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/16011 (20130101) C12N 2770/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662242 | Majeti et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Ravindra Majeti (Palo Alto, California); Irving L. Weissman (Stanford, California) |
ABSTRACT | Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and therapeutic targets. |
FILED | Thursday, September 14, 2017 |
APPL NO | 15/704790 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0093 (20130101) C12N 5/0694 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57426 (20130101) G01N 2500/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662246 | Wisniewski et al. |
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FUNDED BY |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Thomas Wisniewski (Staten Island, New York); Allal Boutajangout (New York, New York) |
ABSTRACT | The present invention is directed to an anti-prion monoclonal antibody and its use for the treatment of conditions associated with or mediated by proteins or peptides having a toxic oligomeric form. These conditions include, but are not limited to, Alzheimer's disease, frontotemporal dementias, traumatic brain injury, and chronic traumatic encephalopathy. |
FILED | Tuesday, July 10, 2018 |
APPL NO | 16/031418 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) C07K 16/1036 (20130101) C07K 16/2872 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662409 | Cairns et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Dana Cairns (Somerville, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
ABSTRACT | In some embodiments, the present invention provides methods including the steps of providing one or more human somatic cells, causing transient increased expression of OCT4, KLF4, SOX2, and cMYC in the somatic cells forming modified somatic cells, providing a plurality of inactivated embryonic fibroblasts, associating the modified somatic cells with the inactivated embryonic fibroblasts in a culture media comprising 20% KO DMEM xeno-free serum replacement and at least 15 ng/ml recombinant bFGF to form human induced neural stem cells. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/757056 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0623 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/67 (20130101) C12N 15/85 (20130101) C12N 2740/15041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662423 | Higgins et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Darren E. Higgins (Jamaica Plain, Massachusetts); Michael N. Starnbach (Needham, Massachusetts); Todd Gierahn (Brookline, Massachusetts); Nadia R. Roan (San Francisco, California) |
ABSTRACT | Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection. |
FILED | Monday, February 12, 2018 |
APPL NO | 15/894537 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) Peptides C07K 14/295 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1034 (20130101) C12N 15/1037 (20130101) Original (OR) Class C12N 15/1072 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662429 | Milsom et al. |
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FUNDED BY |
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APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Michael Milsom (Dossenheim, Germany); David A. Williams (Dover, Massachusetts); Richard Gregory (Brookline, Massachusetts) |
ABSTRACT | Embodiments herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies such as sickle cell disease or thalassemia by increasing the expression levels of fetal hemoglobin levels. |
FILED | Wednesday, March 27, 2019 |
APPL NO | 16/366900 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2740/10032 (20130101) C12N 2740/10043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662432 | Mirsky et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Ethan Mirsky (San Francisco, California); Karsten Temme (San Francisco, California); Christopher A. Voigt (Belmont, Massachusetts); Dehua Zhao (Allston, Massachusetts) |
ABSTRACT | Methods for making synthetic gene clusters are described. |
FILED | Friday, September 15, 2017 |
APPL NO | 15/706353 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/26 (20130101) C07K 14/255 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0095 (20130101) C12N 15/52 (20130101) C12N 15/63 (20130101) C12N 15/67 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class Enzymes C12Y 118/06001 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 30/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662464 | Broadt et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); American International Biotechnology, LLC (Richmond, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Serv (Bethesda, Maryland); American International Biotechnology, LLC (Richmond, Virginia) |
INVENTOR(S) | Trevor Lane Broadt (Frederick, Maryland); Michael D. Harwich (Richmond, Virginia); William T. Budd (Louisa, Virginia); Gregory A. Meyers (Midlothian, Virginia) |
ABSTRACT | Described herein are massively parallel sequencing methods for virus-derived therapeutics such as viral vaccines, including the PVS-RIPO vaccine. The methods allow for the determination of micro-heterogeneity and quantitation of low frequency sequence variants and in the case of PVS-RIPO, are expected to replace the monkey neurovirulence safety test (MNVT) and the mutant analysis by PCR and restriction enzyme cleavage (MAPREC) methods that are currently used to screen lots of RNA virus-derived therapeutics. |
FILED | Friday, July 29, 2016 |
APPL NO | 15/580299 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/86 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/701 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/319 (20130101) C12Q 2521/319 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2600/156 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662476 | Sadhasivam et al. |
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APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
INVENTOR(S) | Senthilkumar Sadhasivam (Mason, Ohio); Vidya Chidambaran (Cincinnati, Ohio); John McAuliffe (Cincinnati, Ohio); Kejian Zhang (Cincinnati, Ohio); Jaroslaw Meller (Cincinnati, Ohio); Cynthia A. Prows (Cincinnati, Ohio); Tsuyoshi Fukuda (Cincinnati, Ohio) |
ABSTRACT | Methods and compositions disclosed herein generally relate to methods of improving clinical and economic outcomes to address adverse effects related to anesthesia, analgesics, opioids, and inadequate pain relief. Embodiments of the invention relate to the association between genes, specific polymorphisms of genes, and non-genetic factors with inadequate pain relief and anesthesia-, analgesic, and/or opioid-related adverse effects. Embodiments of the invention can be used to determine and manage patient risk factors for development of adverse perioperative effects and can allow for personalized anesthesia and pain management for improvement of pain control and reduction of anesthesia-, analgesic-, and opioid-related adverse outcomes. These methods and compositions apply to non-surgical pain management with opioids. Therefore, patients who are genetically predisposed to risk of inadequate pain relief and/or serious side effects from anesthesia, analgesics, and/or opioids can be identified and individualized treatment plans developed for implementation by the clinician to improve clinical and economic outcomes. |
FILED | Thursday, March 08, 2018 |
APPL NO | 15/915581 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663442 | Forzani et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
INVENTOR(S) | Erica Forzani (Mesa, Arizona); Nongjian Tao (Fountain Hills, Arizona); Di Zhao (Tempe, Arizona); Francis Tsow (San Jose, California) |
ABSTRACT | A method for CO2 detection includes obtaining a gas sample; exposing a CO2 sensor to the gas sample, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface; compensating for humidity and temperature; coupling at least one light source to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change; measuring flow; and receiving signals from the at least one light source by at least one photodiode which responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity. |
FILED | Tuesday, February 19, 2019 |
APPL NO | 16/279698 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0059 (20130101) A61B 5/082 (20130101) A61B 2560/0242 (20130101) A61B 2560/0252 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8483 (20130101) G01N 33/004 (20130101) Original (OR) Class G01N 33/497 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663450 | Tian et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Francisco Bezanilla (Chicago, Illinois); Yuanwen Jiang (Chicago, Illinois); João L. Carvalho-de-Souza (Chicago, Illinois) |
ABSTRACT | Provided herein are Si-based materials, methods of making the Si-based materials, and methods for using the Si-based materials. In embodiments, a silicon-based material comprises an aggregate of particles, the particles comprising an ordered array of nanostructures, the nanostructures comprising amorphous silicon, wherein at least some pairs of adjacent nanostructures are connected by one or more bridges comprising amorphous silicon, the one or more bridges extending from the surface of one nanostructure of the pair to the surface of the other nanostructure in the pair. |
FILED | Wednesday, June 14, 2017 |
APPL NO | 15/623133 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/24 (20130101) C23C 16/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class G01N 33/5014 (20130101) G01N 33/5061 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663467 | Johnson |
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FUNDED BY |
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APPLICANT(S) | Raymond M. Johnson (Indianapolis, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Raymond M. Johnson (Indianapolis, Indiana) |
ABSTRACT | Methods for identifying and isolating CD8 T cells that produce interleukin-13 upon activation are provided. The present methods leverage one or more newly-identified biomarkers to identify such CD8 T cells and, in certain cases, sort the same. Certain methods comprise obtaining a sample from a mammal, quantifying a level of expression of one or more biomarkers therein, and determining if the level of expression is elevated as compared, wherein an elevated expression level is indicative of an active disease state. Antisera and antibodies are also provided. In particular, an anti-C10orf128 antiserum formulated against a particular peptide is provided, such anti-C10orf128 antiserum characterized in that it identifies a subset of CD8 T cells that produce interleukin-13 upon activation. |
FILED | Tuesday, June 20, 2017 |
APPL NO | 15/627755 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/28 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0087 (20130101) C12N 5/0638 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/6869 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/295 (20130101) G01N 2333/5409 (20130101) G01N 2333/5437 (20130101) G01N 2333/70517 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663471 | Peterson et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Kansas (Lawrence, Kansas) |
ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
INVENTOR(S) | Blake R. Peterson (Lawrence, Kansas); Digamber Rane (Lawrence, Kansas) |
ABSTRACT | A compound can be a pro-fluorophore peroxynitrite sensor that generates a fluorophore when cleaved by peroxynitrite, having a structure of Formula A: wherein: moiety A is an ER-targeting fluorophore; Y is a linker; and moiety B is a phenol, substituted or unsubstituted, wherein the structure of Formula A is less fluorescent than the ER-targeting fluorophore moiety A. |
FILED | Friday, March 22, 2019 |
APPL NO | 16/362280 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 57/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/533 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 2500/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663474 | Sidhu et al. |
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FUNDED BY |
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APPLICANT(S) | The Governing Council of the University of Toronto (Toronto, Canada); Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Governing Council of the University of Toronto (Toronto, Canada); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Sachdev S. Sidhu (Toronto, Canada); Sarah L. Barker (Toronto, Canada); Orson W. Moe (Dallas, Texas); Makoto Kuro-o (Tochigi, Japan); Johanne Pastor (Flower Mound, Texas) |
ABSTRACT | An antibody and/or binding fragment thereof, wherein the antibody and/or binding fragment thereof comprises a light chain variable region and a heavy chain variable region, the light chain variable region comprising complementarity determining region (CDR) CDR-L3 and the heavy chain variable region comprising CDR-H1, CDR-H2 and CDR-H3, with the amino acid sequences of said CDRs comprising one or more of the sequences set forth below: CDR-L3; selected from any one of SEQ ID NOs: 123, 126-130, 142, 148 or 149; CDR-H1: SEQ ID NOs: 121 or 124; CDR-H2; SEQ ID NOs: 122 or 125; and/or CDR-H3: selected from any one of SEQ ID NOs: 196-226. |
FILED | Friday, February 03, 2017 |
APPL NO | 16/075033 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2319/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/541 (20130101) G01N 33/573 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/347 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663475 | Ranum et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
INVENTOR(S) | Laura Ranum (Gainesville, Florida); Tao Zu (Gainesville, Florida) |
ABSTRACT | Disclosed herein are methods and compositions for identifying and/or treating subjects having or likely to have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD). Antibodies specific for one or more di-amino acid repeat-containing proteins are also provided herein. |
FILED | Monday, March 25, 2019 |
APPL NO | 16/362908 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Separation B01D 21/262 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/285 (20130101) G01N 2800/2835 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663553 | Ernst et al. |
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FUNDED BY |
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APPLICANT(S) | KINETICOR, INC. (Honolulu, Hawaii) |
ASSIGNEE(S) | Kineticor, Inc. (Honolulu, Hawaii) |
INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Oliver Speck (Magdeburg, Germany) |
ABSTRACT | Systems, methods, and devices for intra-scan motion correction to compensate not only from one line or acquisition step to the next, but also within each acquisition step or line in k-space. The systems, methods, and devices for intra-scan motion correction can comprise updating geometry parameters, phase, read, and/or other encoding gradients, applying a correction gradient block, and/or correcting residual errors in orientation, pose, and/or gradient/phase. |
FILED | Thursday, February 09, 2017 |
APPL NO | 15/429002 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56509 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665001 | Horstmeyer et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Roarke W. Horstmeyer (San Marino, California); Changhuei Yang (Alhambra, California) |
ABSTRACT | Certain aspects pertain to Fourier ptychographic tomographic systems and methods for acquiring a plurality of uniquely illuminated intensity measurements based on light passing through a thick sample from plane wave illumination at different angles and for constructing three-dimensional tomographic data of the thick sample by iteratively determining three-dimensional tomographic data in the Fourier domain that is self-consistent with the uniquely illuminated intensity measurements. |
FILED | Thursday, January 21, 2016 |
APPL NO | 15/003559 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665443 | Ibrahim et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Yehia M Ibrahim (Richland, Washington); Richard D. Smith (Richland, Washington) |
ABSTRACT | An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation direction, each opposing electrode arrangement including an arrangement of RF electrodes situated to receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes of the arrangement of RF electrodes so as to provide the confining of ions between the first pair of opposing electrode arrangements, and a second pair of opposing electrode arrangements that confine the ions between the second pair in the confinement volume inwardly laterally in a second confinement direction that complements the first confinement direction, each opposing electrode arrangement of the second pair including an arrangement of RF electrodes that receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes. |
FILED | Thursday, February 28, 2019 |
APPL NO | 16/289216 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/062 (20130101) H01J 49/063 (20130101) H01J 49/065 (20130101) H01J 49/0095 (20130101) Original (OR) Class H01J 49/4235 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666592 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
INVENTOR(S) | Patrick D. Hsu (San Diego, California); Silvana Konermann (San Diego, California) |
ABSTRACT | Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA. |
FILED | Monday, December 31, 2018 |
APPL NO | 16/237381 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/8201 (20130101) C12N 15/8213 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/08 (20130101) H04L 9/30 (20130101) H04L 45/745 (20130101) H04L 51/08 (20130101) H04L 51/12 (20130101) Original (OR) Class H04L 51/14 (20130101) H04L 51/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10667404 | Greenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Greenberg (Los Angeles, California); Neil Talbot (Montrose, California); Jordan Neysmith (Pasadena, California); Dilek Guven (Ankara, Turkey); James Little (Saugus, California); Brian Mech (Stevenson Ranch, California); Mark Humayun (Glendale, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California); Doheny Eye Institute (Los Angeles, California) |
INVENTOR(S) | Robert Greenberg (Los Angeles, California); Neil Talbot (Montrose, California); Jordan Neysmith (Pasadena, California); Dilek Guven (Ankara, Turkey); James Little (Saugus, California); Brian Mech (Stevenson Ranch, California); Mark Humayun (Glendale, California) |
ABSTRACT | Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue. |
FILED | Sunday, October 28, 2007 |
APPL NO | 11/926046 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/0543 (20130101) A61N 1/36036 (20170801) A61N 1/36046 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/0011 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49124 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 10660561 | Bao et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Jie Bao (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
ABSTRACT | A personal skin lesion scanner system that can facilitate early detection of changes in the appearance of a user's skin is described. The system includes a handheld device for home use, to record images of a user's skin, and software for analyzing the images. The system can automatically detect changes in the user's skin, such as changes in the size, shape, or color of a skin lesion, and alert the user if any changes are detected. |
FILED | Monday, February 25, 2013 |
APPL NO | 13/775780 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/0077 (20130101) A61B 5/444 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660569 | Simons et al. |
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FUNDED BY |
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APPLICANT(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
ASSIGNEE(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
INVENTOR(S) | Stephen Simons (Raleigh, North Carolina); Mario Aguilar-Simon (Chapel Hill, North Carolina); Patrick Connolly (Cary, North Carolina); Rolando Estrada (Chapel Hill, North Carolina); Renee Shimizu (Durham, North Carolina); Mary Whatley (Durham, North Carolina) |
ABSTRACT | Provided is an apparatus, system, and method for targeted memory enhancement. A computer processing circuit receives a plurality of electroencephalography (EEG) signals from a plurality of spatially separated EEG sensors located on the head of a subject that is asleep. A first process of the computer processing system determines a sleep state of the subject and upon determining that the subject is in sleep stage 2 or 3 based on a specific EEG signal, the processing system triggers a second process of the computer processing system that determines a transition event in the specific EEG signal, and upon detecting the transition event delivers an intervention to the subject designed to evoke a specific neurophysiological change to the subject. |
FILED | Friday, September 29, 2017 |
APPL NO | 15/720621 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/0482 (20130101) A61B 5/4812 (20130101) A61B 5/6803 (20130101) Original (OR) Class A61B 5/7282 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2230/04 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36031 (20170801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661261 | Jones et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York); LEIDOS, Inc. (Reston, Virginia) |
ASSIGNEE(S) | The Research Foundation For The State University of New York (Binghamton, New York); LEIDOS, Inc. (Reston, Virginia) |
INVENTOR(S) | Wayne E. Jones (Vestal, New York); Jian Liu (Beijing, China PRC); William E. Bernier (Endwell, New York); Julia B. Tollin (Bellmore, New York); Danielle McCarthy (Johnson City, New York); Emilly Obuya (Troy, New York); Jared DeCoste (Bel Air, Maryland) |
ABSTRACT | Mixed-phase TiO2 nanofibers prepared via a sol-gel technique followed by electrospinning and calcination are provided as photocatalysts. The calcination temperature is adjusted to control the rutile phase fraction in TiO2 nanofibers relative to the anatase phase. Post-calcined TiO2 nanofibers composed of 38 wt % rutile and 62 wt % anatase exhibited the highest initial rate constant of UV photocatalysis. This can be attributed to the combined influences of the fibers' specific surface areas and their phase compositions. |
FILED | Monday, March 14, 2016 |
APPL NO | 15/069764 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 23/06 (20130101) B01J 23/42 (20130101) B01J 31/38 (20130101) Original (OR) Class B01J 31/1691 (20130101) B01J 35/004 (20130101) B01J 35/06 (20130101) B01J 35/0013 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 37/036 (20130101) B01J 37/082 (20130101) B01J 37/086 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/725 (20130101) C02F 2305/08 (20130101) C02F 2305/10 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/624 (20130101) C04B 35/62259 (20130101) C04B 35/62675 (20130101) C04B 35/62844 (20130101) C04B 2235/85 (20130101) C04B 2235/5264 (20130101) C04B 2235/5409 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661339 | Heidloff et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Andrew J. Heidloff (West Des Moines, Iowa); Joel R. Rieken (Nevada, Iowa); Iver E. Anderson (Ames, Iowa) |
ABSTRACT | A method for gas atomization of a titanium alloy, nickel alloy, or other alumina (Al2O3)-forming alloy wherein the atomized particles are exposed as they solidify and cool in a very short time to multiple gaseous reactive agents for the in-situ formation of a passivation reaction film on the atomized particles wherein the reaction film retains a precursor halogen alloying element that is subsequently introduced into a microstructure formed by subsequent thermally processing of the atomized particles to improve oxidation resistance. |
FILED | Monday, November 06, 2017 |
APPL NO | 15/732398 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Original (OR) Class B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 3/14 (20130101) B22F 3/15 (20130101) B22F 3/225 (20130101) B22F 3/1055 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 2003/208 (20130101) B22F 2003/1051 (20130101) B22F 2009/0844 (20130101) B22F 2201/00 (20130101) B22F 2201/03 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661390 | Bandyopadhyay et al. |
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FUNDED BY |
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APPLICANT(S) | Washington State University (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | Amit Bandyopadhyay (Pullman, Washington); Susmita Bose (Pullman, Washington) |
ABSTRACT | Particular aspects provide novel devices for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior macroporous structure in which porosity may vary from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device suitable for bone tissue engineering in a recipient subject. In certain aspects, the device further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless and the growth of cells extending from the surface region inward is promoted. |
FILED | Monday, February 08, 2016 |
APPL NO | 15/017925 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) A61F 2/36 (20130101) A61F 2/367 (20130101) A61F 2/3094 (20130101) A61F 2/3676 (20130101) A61F 2/30942 (20130101) A61F 2002/2817 (20130101) A61F 2002/3093 (20130101) A61F 2002/3097 (20130101) A61F 2002/30004 (20130101) A61F 2002/30006 (20130101) A61F 2002/30011 (20130101) A61F 2002/30028 (20130101) A61F 2002/30115 (20130101) A61F 2002/30118 (20130101) A61F 2002/30179 (20130101) A61F 2002/30224 (20130101) A61F 2002/30235 (20130101) A61F 2002/30322 (20130101) A61F 2002/30593 (20130101) A61F 2002/30616 (20130101) A61F 2002/30677 (20130101) A61F 2002/30838 (20130101) A61F 2002/30909 (20130101) A61F 2230/0006 (20130101) A61F 2230/0058 (20130101) A61F 2230/0069 (20130101) A61F 2250/0014 (20130101) A61F 2250/0023 (20130101) A61F 2250/0026 (20130101) A61F 2310/00017 (20130101) A61F 2310/00023 (20130101) A61F 2310/00029 (20130101) A61F 2310/00047 (20130101) A61F 2310/00053 (20130101) A61F 2310/00113 (20130101) A61F 2310/00155 (20130101) A61F 2310/00179 (20130101) A61F 2310/00185 (20130101) A61F 2310/00227 (20130101) A61F 2310/00293 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/06 (20130101) A61L 27/42 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/427 (20130101) A61L 2300/404 (20130101) A61L 2300/406 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/105 (20130101) B22F 3/1055 (20130101) B22F 3/1109 (20130101) B22F 3/1125 (20130101) B22F 3/1146 (20130101) B22F 2207/17 (20130101) B22F 2998/00 (20130101) B22F 2998/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0006 (20130101) B23K 26/70 (20151001) B23K 26/342 (20151001) Original (OR) Class B23K 2103/14 (20180801) B23K 2103/16 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661623 | Edwards et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel J. Edwards (Alexandria, Virginia); Jeffrey W. Book (Slidell, Louisiana); Trent Young (Alexandria, Virginia); Andrew Quaid (New Orleans, Louisiana) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel J. Edwards (Alexandria, Virginia); Jeffrey W. Book (Slidell, Louisiana); Trent Young (Alexandria, Virginia); Andrew Quaid (New Orleans, Louisiana) |
ABSTRACT | A multi-modal vehicle includes a main fuselage body; one or more wings extending from the main fuselage body and having a shape configured to provide aerodynamic lift when the vehicle travels through the air and hydrodynamic lift when the vehicle travels through the water; and a buoyancy control engine situated within the vehicle and configured to control the buoyancy of the vehicle relative to surrounding water when the vehicle is submerged in water, thereby providing a buoyancy force to selectively propel the vehicle upwards and downwards, respectively, through the water. |
FILED | Thursday, March 01, 2018 |
APPL NO | 15/909508 |
ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Vehicles for Use Both on Rail and on Road; Amphibious or Like Vehicles; Convertible Vehicles B60F 5/02 (20130101) Original (OR) Class Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/22 (20130101) B63G 2008/002 (20130101) Aeroplanes; Helicopters B64C 3/10 (20130101) B64C 37/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661869 | Freeman |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Simon E. Freeman (Alexandria, Virginia) |
ABSTRACT | An acoustically stealthy, soft-bodied underwater propulsion system includes a central chord member and a series of successive muscle layers each having a skeletal mechanism and a set of actuators. Each skeletal mechanism includes a central vertebra, two or more actuator arms extending radially outward from the central vertebra and disposed axially symmetrically about the central chord member, and an actuator plate extending from a radially outward end of each actuator arm and oriented substantially transverse to the actuator arm. Each actuator is situated between an actuator plate from a first muscle layer of the series and a second muscle layer of the series. |
FILED | Wednesday, December 12, 2018 |
APPL NO | 16/218239 |
ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/1075 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/08 (20130101) B63G 2008/002 (20130101) B63G 2008/004 (20130101) Marine Propulsion or Steering B63H 1/36 (20130101) Original (OR) Class B63H 21/17 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/09 (20130101) H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661917 | Stouffer et al. |
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FUNDED BY |
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APPLICANT(S) | Charles Stouffer (Lexington Park, Maryland); Ronald Bush (Bradfordsville, Kentucky); Joan Melendez (Jacksonville, Florida); David Hohn (San Diego, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Charles Stouffer (Lexington Park, Maryland); Ronald Bush (Bradfordsville, Kentucky); Joan Melendez (Jacksonville, Florida); David Hohn (San Diego, California) |
ABSTRACT | A vent wash cover for covering an aircraft vent with a plurality of slots. The vent wash cover includes a main body, fingers, a threaded aperture, and a hollow conic section. The main body has a first end and a second end. The fingers are disposed on the first end and correspond in size and placement to the plurality of slots such that a seal is created between the fingers and plurality of slots. The threaded aperture is disposed on the second end, and corresponds to threads of a standard thread extension pole. The hollow conic section extends outward from the threaded aperture such that the threads of the standard thread extension pole can be properly aligned from a distance for insertion into the threaded aperture. |
FILED | Monday, April 16, 2018 |
APPL NO | 15/953681 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/30 (20170101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662058 | Dosev |
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FUNDED BY |
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APPLICANT(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
ASSIGNEE(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
INVENTOR(S) | Dosi Dosev (Chanhassen, Minnesota) |
ABSTRACT | A method of manufacturing a patterned aluminum nitride layer includes growing an amorphous patterned layer on a seed layer, which promotes growth of a first type aluminum nitride layer that has a disordered crystallographic structure. The seed layer promotes growth of a second type aluminum nitride layer with a vertically oriented columnar crystal structure. The method also includes depositing an aluminum nitride layer over the amorphous patterned layer and the seed layer to form the first type aluminum nitride layer with the disordered crystallographic structure over the amorphous patterned layer and the second type aluminum nitride layer with the vertically oriented columnar crystal structure over the seed layer. The method also includes depositing a masking layer over the second type aluminum nitride layer and etching away the first type aluminum nitride layer. |
FILED | Tuesday, March 05, 2019 |
APPL NO | 16/292926 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00595 (20130101) Original (OR) Class B81C 2201/0133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662062 | Qadri et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Syed B. Qadri (Fairfax Station, Virginia); Bhakta B. Rath (Oakton, Virginia); Edward P. Gorzkowski, III (Odenton, Maryland) |
ABSTRACT | Si3N4 nanotubes and nanorods wherein the nanotubes and nanorods of silicon nitride are pure α-Si3N4 formed by carbothermal reduction of SiO2 from reacting agricultural husk material in heat and forming the silicon nitride nanotubes and nanorods. |
FILED | Monday, February 04, 2019 |
APPL NO | 16/267187 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0685 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662274 | Kohl et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); Oluwadamilola Phillips (Atlanta, Georgia); Jared Schwartz (Atlanta, Georgia); Gerald Gourdin (Columbus, Ohio); Anthony Engler (Atlanta, Georgia); Jisu Jiang (Atlanta, Georgia) |
ABSTRACT | Self-immolative polymers and compositions comprising such polymers are described. The polymers are copolymers of phthalaldehyde and one or more additional aldehydes and can degrade/decompose upon exposure to a desired stimulus, like light, heat, sound, or chemical trigger. The copolymers can be linear or cyclic, and can be crosslinked or uncrosslinked. Polymer compositions, including multilayered and multiregioned compositions, containing the copolymers are disclosed. These compositions can contain agents such as crosslinking agents, crosslinking catalysts, photocatalysts, thermocatalyst, sensitizers, chemical amplifiers, freezing point depressing agent, photo-response delaying agents, and the like. Methods of making and using the copolymers are also described. |
FILED | Monday, December 04, 2017 |
APPL NO | 15/830864 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) B32B 27/42 (20130101) B32B 2307/54 (20130101) B32B 2307/716 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2/20 (20130101) C08G 6/00 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 2361/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/01 (20130101) C08K 5/01 (20130101) C08K 5/03 (20130101) C08K 5/0008 (20130101) C08K 5/10 (20130101) C08K 5/10 (20130101) C08K 5/0016 (20130101) C08K 5/17 (20130101) C08K 5/17 (20130101) C08K 5/0025 (20130101) C08K 5/42 (20130101) C08K 5/42 (20130101) C08K 5/55 (20130101) C08K 5/55 (20130101) Compositions of Macromolecular Compounds C08L 61/02 (20130101) C08L 61/02 (20130101) C08L 61/02 (20130101) C08L 61/02 (20130101) C08L 61/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662329 | Hreha et al. |
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FUNDED BY |
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APPLICANT(S) | Jalapeno Holdings, LLC (Bellbrook, Ohio) |
ASSIGNEE(S) | Jalapeno Holdings, LLC (Bellbrook, Ohio) |
INVENTOR(S) | Richard D. Hreha (Centerville, Ohio); Joel P. Brubaker (Dayton, Ohio); Frank M. Zalar (Beavercreek Township, Ohio); Michael D. Rauscher (Beavercreek, Ohio) |
ABSTRACT | Chemical compositions are provided having a structure in accordance with with the R group having a structure in accordance with R1 includes an alkyl group, R2 includes an alkylene group, and R3 includes an alkylene group in accordance with (CH2), with x≥2, and R4 includes the structure of Formula (II) or Formula (III). R5 includes a meta-substituted or para-substituted phenyl moiety. Additionally, elastomers produced by cross-linking the chemical composition of Formula (I) are provided. |
FILED | Tuesday, June 26, 2018 |
APPL NO | 16/019015 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/388 (20130101) C08G 77/445 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 5/047 (20130101) C08J 2383/10 (20130101) C08J 2477/10 (20130101) Compositions of Macromolecular Compounds C08L 77/10 (20130101) C08L 83/04 (20130101) Original (OR) Class C08L 2312/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662338 | Matzdorf et al. |
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FUNDED BY |
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APPLICANT(S) | Craig Matzdorf (Hollywood, Maryland); Joshua Walles (California, Maryland); Kaitlyn Thompson (San Diego, California) |
ASSIGNEE(S) | The United States of America as represented by the secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Craig Matzdorf (Hollywood, Maryland); Joshua Walles (California, Maryland); Kaitlyn Thompson (San Diego, California) |
ABSTRACT | Composition and process for preparing corrosion-resistant passive coatings on bulk-aluminum alloys and aluminum powder-pigments; said coatings derived from an acidic aqueous composition consisting essentially of potassium hexafluorozirconate, basic chromium sulfate and potassium tetrafluoroborate. |
FILED | Thursday, September 06, 2018 |
APPL NO | 16/123605 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/084 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/34 (20130101) C23C 22/83 (20130101) C23C 24/10 (20130101) C23C 2222/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
10662415 — Engineered biosynthetic pathways for production of (6E)-8-hydroxygeraniol by fermentation
US 10662415 | Tracewell et al. |
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FUNDED BY |
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APPLICANT(S) | Zymergen Inc. (Emeryville, California) |
ASSIGNEE(S) | Zymergen Inc. (Emeryville, California) |
INVENTOR(S) | Cara Ann Tracewell (Walnut Creek, California); Steven M. Edgar (Albany, California); Stepan Tymoshenko (Emeryville, California); Alexander Glennon Shearer (San Francisco, California) |
ABSTRACT | The present disclosure describes the engineering of microbial cells for fermentative production of (6E)-8-hydroxygeraniol and provides novel engineered microbial cells and cultures, as well as related (6E)-8-hydroxygeraniol production method. |
FILED | Monday, June 24, 2019 |
APPL NO | 16/450780 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 9/0006 (20130101) C12N 9/16 (20130101) Original (OR) Class C12N 9/0073 (20130101) C12N 9/90 (20130101) C12N 9/1085 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/18 (20130101) Enzymes C12Y 101/01034 (20130101) C12Y 114/13152 (20150701) C12Y 205/0101 (20130101) C12Y 205/01001 (20130101) C12Y 301/07011 (20150701) C12Y 503/03002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662426 | Lynch et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Ashley Delanie Trahan (Hillsborough, North Carolina); Daniel Rodriguez (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina); Charles Bridwell Cooper (Durham, North Carolina); Ahmet Bozdag (Raleigh, North Carolina) |
ABSTRACT | This invention relates to metabolically engineered microorganisms, such as bacterial and or fungal strains, and bioprocesses utilizing such strains. These strains enable the dynamic control of metabolic pathways, which can be used to optimize production. Dynamic control over metabolism is accomplished via a combination of methodologies including but not limited to transcriptional silencing and controlled enzyme proteolysis. These microbial strains are utilized in a multi-stage bioprocess encompassing at least two stages, the first stage in which microorganisms are grown and metabolism can be optimized for microbial growth and at least one other stage in which growth can be slowed or stopped, and dynamic changes can be made to metabolism to improve the production of desired product, such as a chemical or fuel. |
FILED | Thursday, June 11, 2015 |
APPL NO | 15/317768 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/111 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2320/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662457 | Dresios et al. |
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FUNDED BY |
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APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
INVENTOR(S) | John Dresios (Carlsbad, California); Richard Holmes Griffey (Vista, California); Challise J. Sullivan (San Diego, California); Erik D. Pendleton (San Diego, California); Henri M. Sasmor (Oceanside, California); William L. Hicks (San Diego, California); Eric M. Amendt (San Diego, California) |
ABSTRACT | A portable fluidic platform for rapid and flexible end-to-end production of recombinant protein biologics includes a bioreactor system hosting stable and robust cell-free translation systems that is fluidically integrated with modular protein separation functionalities (e.g., size exclusion, ion exchange or affinity chromatography systems) for purification of the cell-free expressed product and which are configurable for process-specific isolation of different proteins, as well as for formulation. The bioreactor utilizes lysates from engineered eukaryotic (e.g., yeast) or prokaryotic (e.g., bacterial) strains that contain factors for protein folding and posttranslational modifications. Combination of various purification modules on the same fluidic platform allows flexibility of re-routing for purification of different proteins depending on specific target requirements. Protein synthesis and purification modules are integrated into self-contained disposable fluidic cartridge that eliminates cross-contamination between runs. The platform allows for flexible production of protein biologics within 24 hours (from DNA to purified product). |
FILED | Friday, February 16, 2018 |
APPL NO | 15/898273 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662792 | Harris et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Meggan Harris (Colchester, Connecticut); Alexander W. Williams (Windsor Locks, Connecticut); Sheree R. Swenson-Dodge (Lebanon, Connecticut) |
ABSTRACT | A cooling arrangement for a turbine engine includes a cooling source and first and second structures. A ceramic-based composite cooling tube fluidly provides a fluid connection between the first and second structures. The cooling tube is configured to transfer a cooling fluid from the cooling source to the second structure. |
FILED | Thursday, January 29, 2015 |
APPL NO | 15/113116 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 25/005 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101) F05D 2240/15 (20130101) F05D 2260/20 (20130101) F05D 2260/98 (20130101) F05D 2260/232 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662797 | Roy Thill |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Carson A. Roy Thill (South Berwick, Maine) |
ABSTRACT | A multi-plane annular brush seal includes a front plate, a back plate, and a plurality of bristles. Each of the plurality of bristles has a first lengthwise portion extending from the base end, a second lengthwise portion, and a third lengthwise portion. The front plate and back plate are configured to maintain the bristle first lengthwise portions substantially parallel to a first plane, the second lengthwise portion of the bristles through a transition region, and the bristle third lengthwise portions substantially parallel to a second plane. The first plane is skewed from the second plane by an obtuse angle. At least some of the bristle second lengthwise portions are maintained in contact with the front plate through the transition region and at least some of the bristle second lengthwise portions are maintained in contact with the back plate through the transition region. |
FILED | Thursday, April 05, 2018 |
APPL NO | 15/946143 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/06 (20130101) Pistons; Cylinders; Sealings F16J 15/3288 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663167 | Dziech |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Aaron Michael Dziech (Crittenden, Kentucky) |
ABSTRACT | Combustor assemblies are provided. An exemplary combustor assembly comprises an annular ceramic matrix composite (CMC) inner liner including an inner liner flange, an annular CMC outer liner including an outer liner flange, and an annular CMC combustor dome comprising a plurality of tiles positioned circumferentially adjacent one another. Each tile has a first end radially opposite a second end. The CMC inner liner, outer liner, and combustor dome form a combustor, and the CMC combustor dome is positioned at a combustor forward end. The combustor assembly also comprises a support structure for supporting the combustor and including an annular frame having a frame channel defining a groove and an inner and outer support flanges. The first end of each tile is disposed within the frame channel groove. The inner liner flange is secured to the inner support flange and the outer liner flange is secured to the outer support flange. |
FILED | Friday, June 16, 2017 |
APPL NO | 15/625489 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/15 (20130101) F05D 2240/35 (20130101) F05D 2240/90 (20130101) Casings, Linings, Walls or Doors Specially Adapted for Combustion Chambers, e.g Firebridges; Devices for Deflecting Air, Flames or Combustion Products in Combustion Chambers; Safety Arrangements Specially Adapted for Combustion Apparatus; Details of Combustion Chambers, Not Otherwise Provided for F23M 5/00 (20130101) F23M 5/04 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/007 (20130101) Original (OR) Class F23R 3/50 (20130101) F23R 3/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663272 | Diviacchi et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Giancarlo Diviacchi (Baltimore, Maryland); Joseph A Domanico (Bel Air, Maryland); Joseph E May (Clemont, Florida); David R Redding (Jarrettsville, Maryland) |
ABSTRACT | The present invention is directed to a novel, low-toxicity and environmentally-friendly violet smoke generating composition. The composition comprises a mixture of at least one red dye and at least one blue dye, a coolant, an oxidizer, a binder, and a non-sulfur particulate fuel that is also a burn-control agent having two different particle size distributions. Preferably the fuel comprises a mixture of granulated sucrose and sucrose 10×. |
FILED | Tuesday, November 06, 2018 |
APPL NO | 16/181580 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/48 (20130101) Original (OR) Class Digital Fluid-pressure Computing Devices G06D 3/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663389 | O'Brien et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Casey P. O'Brien (Granger, Indiana); Ivan C. Lee (Burtonsville, Maryland); Zachary W. Dunbar (Annandale, Virginia) |
ABSTRACT | A permeation cell device includes a body component, a wire mesh support structure positioned in the body component, a membrane over the wire mesh support structure, a pair of compressible gaskets sandwiching the membrane, and a flange compressing the membrane. A spectroscopic device contains the permeation cell device. At least one mechanism simultaneously performs an infrared-reflection absorption spectroscopic analysis of a surface of the membrane as a fluid permeates on the membrane and measures a trans-membrane fluid permeation rate across the membrane. The wire mesh support structure may be configured to provide mechanical support to the non-opaque membrane at a pressure of at least 1 atm. The permeation cell device and the spectroscopic device may collectively create a pair of separate isolated compartments. The body component may include a material that is non-permeable to the fluid. |
FILED | Thursday, March 29, 2018 |
APPL NO | 15/939333 |
ART UNIT | 2854 — Printing/Measuring and Testing |
CURRENT CPC | Separation B01D 53/228 (20130101) B01D 65/10 (20130101) B01D 71/022 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0806 (20130101) G01N 15/0826 (20130101) Original (OR) Class G01N 21/3504 (20130101) G01N 2021/3595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663450 | Tian et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Francisco Bezanilla (Chicago, Illinois); Yuanwen Jiang (Chicago, Illinois); João L. Carvalho-de-Souza (Chicago, Illinois) |
ABSTRACT | Provided herein are Si-based materials, methods of making the Si-based materials, and methods for using the Si-based materials. In embodiments, a silicon-based material comprises an aggregate of particles, the particles comprising an ordered array of nanostructures, the nanostructures comprising amorphous silicon, wherein at least some pairs of adjacent nanostructures are connected by one or more bridges comprising amorphous silicon, the one or more bridges extending from the surface of one nanostructure of the pair to the surface of the other nanostructure in the pair. |
FILED | Wednesday, June 14, 2017 |
APPL NO | 15/623133 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/24 (20130101) C23C 16/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class G01N 33/5014 (20130101) G01N 33/5061 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663579 | Stanley et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Byron McCall Stanley (Newton, Massachusetts); Matthew Tyler Cornick (San Diego, California) |
ABSTRACT | A method for extending a surface penetrating radar (SPR) footprint for performing localization with an SPR system is disclosed. The method may include may include transmitting at least one SPR signal from at least one SPR transmit element. The method may further include receiving a response signal via at least two SPR receive elements, the response signal including, at least in part, a reflection of the SPR signal from an object. The method may also include determining that the object is in a region of interest outside a footprint of the SPR system based on a difference in phase at which the response signal is received at the at least two SPR receive elements. The method may additionally include performing localization of a vehicle using the SPR system based at least in part on the object. |
FILED | Monday, January 29, 2018 |
APPL NO | 15/882986 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/06 (20130101) B60W 2550/14 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/26 (20130101) G01C 21/3602 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/411 (20130101) G01S 13/87 (20130101) G01S 13/89 (20130101) G01S 13/862 (20130101) G01S 13/865 (20130101) G01S 13/867 (20130101) G01S 13/872 (20130101) G01S 13/885 (20130101) Original (OR) Class G01S 13/951 (20130101) G01S 2013/9327 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663614 | Wiegert et al. |
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FUNDED BY |
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APPLICANT(S) | Roy F. Wiegert (Panama City, Florida); Kurt A. Giardina (Panama City, Florida) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Roy F. Wiegert (Panama City, Florida); Kurt A. Giardina (Panama City, Florida) |
ABSTRACT | A magnetic anomaly sensing system and method uses two triaxial magnetometer (TM) sensors arranged in a one-dimensional array with the sensors' magnetic sensing axes being parallel to one another. The sensors are spaced-apart from one another along one of the sensing axes by a distance D with a midpoint between the sensors along the one sensing axis being located a distance Z from a reference datum. A processor implements an iterative process to include generating scalar magnitudes of a magnetic anomaly field measured at each of the sensors where the magnetic anomaly field is associated with a magnetic object. A scalar range from the sensors to the magnetic object is generated based on the distance D, the distance Z, and the scalar magnitudes. A magnetic dipole moment of the magnetic object is generated using the scalar range and the scalar magnitudes. |
FILED | Friday, August 04, 2017 |
APPL NO | 15/669164 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 7/06 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/08 (20130101) G01V 3/165 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663631 | Mikkelsen et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Maiken H. Mikkelsen (Durham, North Carolina); David R. Smith (Durham, North Carolina); Gleb M. Akselrod (Durham, North Carolina) |
ABSTRACT | Nanopatch antennas and related methods for enhancing and tailoring are disclosed. According to an aspect, an apparatus includes a conductive material defining a substantially planar surface. The apparatus also includes a conductive nanostructure defining a substantially planar surface. The conductive material and the conductive nanostructure are positioned such that the planar surface of the conductive material faces the planar surface of the conductive nanostructure, such that the planar surfaces are substantially parallel, and such that the planar surfaces are spaced by a selected distance. The apparatus also includes an optically-active material positioned between the planar surfaces. |
FILED | Saturday, October 10, 2015 |
APPL NO | 15/508198 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) H01L 33/26 (20130101) H01L 33/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663666 | Lloyd et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey M. Lloyd (San Diego, California); Brandon J. Wiedemeier (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey M. Lloyd (San Diego, California); Brandon J. Wiedemeier (San Diego, California) |
ABSTRACT | This invention is a method and system for addressing structural weaknesses and geometric differentials introduced to a cable when splicing optic fibers. The apparatus and method utilize structurally integrated layers of protective polymers and bonding materials selected for strength and flexibility relative to their thickness. This results in an apparatus having a minimally increased circumference compared to the cable. The method and apparatus include one or more strengthening layers which allow the repaired cable substantially similar flexibility compared to the cable, but prevent formation of sharp bends or kinks. The strengthening layers also allow the repaired cable a resistance to tension similar to the original cable. The method and apparatus further include an outer layer having a geometric configuration which includes sloped terminating ends designed to prevent the reinforced area of the cable from being damaged by the force of objects or substances in contact with cable. |
FILED | Thursday, December 05, 2013 |
APPL NO | 14/098027 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2011/0075 (20130101) Optical Elements, Systems, or Apparatus G02B 6/2558 (20130101) Original (OR) Class G02B 6/4433 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663667 | Frantz et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jesse A. Frantz (Washington, District of Columbia); Lynda E. Busse (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Ishwar D. Aggarwal (Waxhaw, North Carolina); Catalin M. Florea (Washington, District of Columbia) |
ABSTRACT | A system and method for creating a random anti-reflective surface structure on an optical fiber including a holder configured to hold the optical fiber comprising a groove and a fiber connector, an adhesive material to hold the optical fiber in the holder and fill any gap between the optical fiber and the holder, a glass to cover the adhesive material and the optical fiber, and a reactive ion etch device. The reactive ion etch device comprises a plasma and is configured to expose an end face of the optical fiber to the plasma. The plasma is configured to etch a random anti-reflective surface structure on the end face of the optical fiber. |
FILED | Friday, November 09, 2018 |
APPL NO | 16/185219 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/68 (20130101) C03C 2218/34 (20130101) Optical Elements, Systems, or Apparatus G02B 5/0268 (20130101) G02B 5/1857 (20130101) G02B 6/262 (20130101) Original (OR) Class G02B 6/3584 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 2001/4645 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663766 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
INVENTOR(S) | Zhizhen Ma (Arlington, Virginia); Volker J. Sorger (Alexandria, Virginia) |
ABSTRACT | An electro-optical modulator using a graphene-based plasmonic slot is disclosed. The electro-optical modulator is comprised of a substrate layer, a dielectric spacer, a graphene layer, a first metal layer, and a second metal layer. The metal layers create a plasmonic slot that modulates between a light absorptive and light transparent state depending on the application of voltage across the modulator. Two or four graphene layers may be used to reduce power consumption and the size of the modulator. |
FILED | Monday, February 26, 2018 |
APPL NO | 15/905167 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/17 (20130101) G02F 1/0018 (20130101) Original (OR) Class G02F 1/0081 (20130101) G02F 1/0107 (20130101) G02F 1/174 (20130101) G02F 2201/06 (20130101) G02F 2202/02 (20130101) G02F 2202/10 (20130101) G02F 2202/16 (20130101) G02F 2203/10 (20130101) G02F 2203/48 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663773 | van 't Erve et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Olaf M. J. van 't Erve (Falls Church, Virginia); Connie H. Li (Alexandria, Virginia); Berend T. Jonker (Waldorf, Maryland); Aubrey T. Hanbicki (Washington, District of Columbia); Kathleen M. Mccreary (Washington, District of Columbia) |
ABSTRACT | The spin-Hall effect can be used to modulate the linear polarization of light via the magneto-optical Kerr effect. A central area of an outer surface of an added layer atop a spin Hall material is illuminated while simultaneously passing a modulated electric current through the material, so that reflected light has a new linear polarization that differs from the initial linear polarization to a degree depending on the amplitude of the modulated electric current. |
FILED | Monday, October 29, 2018 |
APPL NO | 16/173724 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0136 (20130101) Original (OR) Class G02F 1/0353 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663859 | Meade et al. |
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FUNDED BY |
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APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
INVENTOR(S) | Roy E. Meade (Boise, Idaho); Gurtej S. Sandhu (Boise, Idaho) |
ABSTRACT | A method of forming a photonic device structure comprises forming a photoresist over a photonic material over a substrate. The photoresist is exposed to radiation through a gray-tone mask to form at least one photoexposed region and at least one non-photoexposed region of the photoresist. The at least one photoexposed region of the photoresist or the at least one non-photoexposed region of the photoresist is removed to form photoresist features. The photoresist features and unprotected portions of the photonic material are removed to form photonic features. Other methods of forming a photonic device structure, and a method of forming an electronic device are also described. |
FILED | Wednesday, February 28, 2018 |
APPL NO | 15/908355 |
ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/00 (20130101) G02B 6/136 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) Original (OR) Class G03F 7/70283 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664141 | Keel et al. |
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FUNDED BY |
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APPLICANT(S) | Paul Erich Keel (Cambridge, Massachusetts); Jeffrey Huang (Lausanne, Switzerland) |
ASSIGNEE(S) | Paul Erich Keel (Cambridge, Massachusetts) |
INVENTOR(S) | Paul Erich Keel (Cambridge, Massachusetts); Jeffrey Huang (Lausanne, Switzerland) |
ABSTRACT | A computer-implemented method of interacting with at least one data item includes storing, in a database system, a configuration, of each of the data items as a distinct information object, in which each information object has an association with a picture, a heading, and a link to the corresponding data item. The method additionally uses the stored configurations to make available for display a representation of each of at least two of the information objects in a uniform format, wherein the format includes a card, and, within the card, the picture, the heading, a set of indicators, the set of indicators having at least one member, and a function mechanism giving graphical access to a set of functions. |
FILED | Wednesday, November 08, 2017 |
APPL NO | 15/806912 |
ART UNIT | 2173 — Graphical User Interface and Document Processing |
CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04817 (20130101) G06F 3/04842 (20130101) Original (OR) Class G06F 16/22 (20190101) G06F 16/29 (20190101) G06F 16/258 (20190101) G06F 16/9535 (20190101) G06F 16/9537 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/046 (20130101) H04L 67/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/99933 (20130101) Y10S 707/99943 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664241 | Aly et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Mohamed Ezzat El Hadedy Aly (Champaign, Illinois); Kevin Skadron (Charlottesville, Virginia) |
ABSTRACT | A method operating a memory system, can be provided by reading a plurality of data words from a memory system, where each of the plurality of data words is stored in the memory system in a first dimension-major order. The plurality of data words can be shifted into a transpose memory system in the first dimension in parallel with one another using first directly time adjacent clock edges to store a plurality of transposed data words in a second dimension-major order in the transpose memory system relative to the memory system. The plurality of transposed data words can be shifted out of the transpose memory system in the second dimension using second directly time adjacent clock edges. |
FILED | Friday, October 13, 2017 |
APPL NO | 15/783548 |
ART UNIT | 2137 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 7/785 (20130101) Original (OR) Class G06F 9/30032 (20130101) G06F 12/1009 (20130101) G06F 15/8007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664560 | Pal et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Deepankar Pal (Jeffersonville, Indiana); Nachiket Patil (Louisville, Kentucky); Brent Stucker (Louisville, Kentucky) |
ABSTRACT | Simulation systems, manufacturing systems, software products and controllers are provided with multi-scale modeling in which a coarse mesh and a fine mesh that models a stimulus are decoupled. The fine mesh can be moved within the coarse mesh with a cut and paste operation. The coarse mesh is updated by sparsely propagated effects through the coarse mesh. Simulations of the invention can be conducted in real-time, and be used as controllers in manufacturing systems, such as additive manufacturing systems. A number of efficient methods are provided for solving meshing determinations that arise from movement of a stimulus modeled within a fine mesh. |
FILED | Friday, December 19, 2014 |
APPL NO | 15/105683 |
ART UNIT | 2127 — AI & Simulation/Modeling |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1057 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/12 (20130101) G06F 2217/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664625 | Kane |
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FUNDED BY |
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APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Michael G. Kane (Princeton, New Jersey) |
ABSTRACT | A device includes a substrate, an array of metal pads on a first surface of the substrate, a carbon polymer composite covering the array of metal pads, the composite having variations that result in random resistance values between the metal pads usable as a random code. A method of manufacturing a secure device, including forming an array of metal pads on a dielet substrate, the dielet substrate containing at least one memory in which is stored an encryption key, and an RF communication section, covering the array of metal pads with a carbon polymer composite such that variations in the carbon concentration in the polymer forms a unique pattern of resistance, attaching the dielet substrate to a host component, receiving a request from a security server for a unique code determined by the unique pattern of resistance, and using the encryption key, encrypting and providing the unique code to the security server. |
FILED | Wednesday, January 06, 2016 |
APPL NO | 15/542469 |
ART UNIT | 2493 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/73 (20130101) G06F 21/86 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/073 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 63/0428 (20130101) H04L 2209/12 (20130101) H04L 2209/805 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664764 | Gundecha et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Tempe, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
INVENTOR(S) | Pritam Gundecha (Tempe, Arizona); Jiliang Tang (Tempe, Arizona); Huan Liu (Tempe, Arizona) |
ABSTRACT | Embodiments of a system for determining personal attributes based on public interaction data are illustrated. In one embodiment, the system employs a process for predicting personal attributes based on public interaction data by constructing matrices based on user interactions drawn from public posts on a social media website. The process may further learn a compact representation for a plurality of users based on public posts using the matrices, extract the compact representation of one or more users that have been labeled, and apply a classifier to learn about a particular personal attribute. Through this, a prediction of personal attributes of users that have not been labeled may be obtained. |
FILED | Monday, May 23, 2016 |
APPL NO | 15/161855 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665529 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | James Paul Smith (Chelmsford, Massachusetts); Bernard A. Malouin, Jr. (Westford, Massachusetts); Eric A. Browne (Westford, Massachusetts) |
ABSTRACT | The present invention generally relates to a modular microjet cooler. The modular microjet cooler may be attached to a packaged heat generating device that is mounted on a printed circuit board. The modular microjet cooler has an inlet allowing supply fluid to be directed through microjet nozzles toward an impingement surface on the packaged device. The modular microjet cooler also has one or more outlets that allow exhaust fluid to be removed. The modular microjet cooler is attached to the device after it has been packaged. Further, the modular microjet cooler may be attached to the packaged device either before or after it is mounted to the printed circuit board. |
FILED | Thursday, July 19, 2018 |
APPL NO | 16/039492 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/13 (20130101) H01L 23/4735 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20927 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665630 | Vincentsen et al. |
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FUNDED BY |
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APPLICANT(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
ASSIGNEE(S) | Wavefront Research, Inc. (Nothampton, Pennsylvania) |
INVENTOR(S) | David M. Vincentsen (Bethlehem, Pennsylvania); Jonas D. Corl (Bethlehem, Pennsylvania); Thomas A. Mitchell (Nazareth, Pennsylvania); Michelle M. Stone (Hellertown, Pennsylvania); Thomas W. Stone (Hellertown, Pennsylvania); Randall C. Veitch (Walnutport, Pennsylvania) |
ABSTRACT | The present disclosure provides an optoelectronic module. In one aspect, the optoelectronic module includes an insertion member including a housing insert and an imager disposed in the housing insert, and a receiving member including an interposer, a housing disposed on the interposer, and an optoelectronic device electrically connected to said interposer. The housing of the receiving member is configured to engage and receive the housing insert of the insertion member. The optoelectronic device of the receiving member is configured to align with the imager of the insertion member. |
FILED | Monday, August 05, 2019 |
APPL NO | 16/532116 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14636 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665730 | Pepin |
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FUNDED BY |
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APPLICANT(S) | Karl A. Pepin (Cape Porpoise, Maine) |
ASSIGNEE(S) | Pepin Technologies LLC. (Cape Porpoise, Maine) |
INVENTOR(S) | Karl A. Pepin (Cape Porpoise, Maine) |
ABSTRACT | A fabric comprising a plurality of photovoltaic filaments includes a conductive bus structure woven into the selvage edge of the fabric, providing a robust and flexible electrical connection from the positive and negative electrode leads of the photovoltaic filaments. The bus structure may be formed in segments which can include any combination of series and parallel configurations to accommodate loads requiring specified voltage and current. |
FILED | Friday, October 20, 2017 |
APPL NO | 15/789110 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Woven Fabrics; Methods of Weaving; Looms D03D 1/0076 (20130101) D03D 5/00 (20130101) D03D 13/004 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/16 (20130101) D10B 2401/18 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/304 (20130101) H01L 31/042 (20130101) H01L 31/0201 (20130101) Original (OR) Class H01L 31/0508 (20130101) H01L 31/02167 (20130101) H01L 31/035281 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665797 | Mei et al. |
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FUNDED BY |
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APPLICANT(S) | WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina); University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina); UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
INVENTOR(S) | Yaochuan Mei (Winston-Salem, North Carolina); Oana Diana Jurchescu (Winston-Salem, North Carolina); Zeev Valentine Vardeny (Salt Lake City, Utah); Chuang Zhang (Salt Lake City, Utah) |
ABSTRACT | In one aspect, field effect transistors are described herein employing channels formed of hybrid halide perovskite materials. For example, a field effect transistor comprises a source terminal, a drain terminal and a gate terminal wherein a dielectric layer is positioned between the gate terminal and the source and drain terminals. A channel layer is in electrical communication with the source terminal and the drain terminal, the channel layer comprising an organic-inorganic perovskite in contact with a polymeric surface of the dielectric layer. |
FILED | Wednesday, November 09, 2016 |
APPL NO | 15/774944 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/005 (20130101) H01L 51/052 (20130101) H01L 51/0077 (20130101) H01L 51/105 (20130101) H01L 51/0541 (20130101) H01L 51/0545 (20130101) H01L 51/0558 (20130101) H01L 51/0566 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665961 | McMahon et al. |
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FUNDED BY |
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APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Benjamin G. McMahon (Nottingham, New Hampshire); Christopher K. Cheung (Newton, Massachusetts); Robert W. Rogers (Rochester, New Hampshire); Court E. Rossman (Merrimack, New Hampshire) |
ABSTRACT | A dual mode array antenna including a ground plane, a plurality of antenna elements, a tuning mechanism for tuning the array antenna to a resonant frequency, and a base defining a cavity having a depth that is less than half of a wavelength at an upper frequency of the array antenna is disclosed. Each of the plurality of antenna elements includes at least one spiral arm and each of the plurality of antenna elements is embedded in the cavity. The dual mode array antenna operates between the upper frequency and a lower frequency and may operate in one or more resonant frequencies. |
FILED | Wednesday, November 21, 2018 |
APPL NO | 16/197703 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 1/247 (20130101) H01Q 1/523 (20130101) H01Q 3/38 (20130101) H01Q 21/22 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666007 | Berkenbush et al. |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Richard E. Berkenbush (Pompton Plains, New Jersey); James W. Holley (Hackettstown, New Jersey) |
ABSTRACT | A cable connector wrench and method of operation that in one example has a shaft with a pair of asymmetrical jaws at one end and a handle coupled to the other end. The two jaws form an assembly in which the jaws are joined with a pivot. The fixed jaw is attachable to the shaft and the movable jaw is coupled to the fixed jaw. The movable jaw and the fixed jaw cooperate to engage a connector of a cabled assembly wherein the connector wrench is adapted for tightening or loosening the connector of the cabled assembly. |
FILED | Wednesday, April 25, 2018 |
APPL NO | 15/962788 |
ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 13/06 (20130101) B25B 13/28 (20130101) B25B 13/30 (20130101) B25B 13/481 (20130101) B25B 13/5016 (20130101) B25B 23/142 (20130101) Handles for Hand Implements B25G 1/005 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 43/26 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666191 | Valdes-Garcia et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alberto Valdes-Garcia (Chappaqua, New York); Bodhisatwa Sadhu (Fishkill, New York) |
ABSTRACT | A voltage controlled oscillator (VCO), a method of designing a voltage controlled oscillator, and a design structure comprising a semiconductor substrate including a voltage controlled oscillator are disclosed. In one embodiment, the VCO comprises an LC tank circuit for generating an oscillator output at an oscillator frequency, and an oscillator core including cross-coupled semiconductor devices to provide feedback to the tank circuit. The VCO further comprises a supply node, a tail node, and a noise by-pass circuit connected to the supply and tail nodes, in parallel with the tank circuit and the oscillator core. The by-pass circuit forms a low-impedance path at a frequency approximately twice the oscillator frequency to at least partially immunize the oscillator core from external noise and to reduce noise contribution from the cross-coupled semiconductor devices. |
FILED | Tuesday, December 05, 2017 |
APPL NO | 15/832069 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 17/505 (20130101) G06F 17/5045 (20130101) G06F 17/5063 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 1/00 (20130101) H03B 5/1212 (20130101) Original (OR) Class H03B 5/1215 (20130101) H03B 5/1228 (20130101) H03B 5/1243 (20130101) H03B 5/1281 (20130101) H03B 2200/009 (20130101) H03B 2200/0038 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666273 | Sternberg et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Oren Sternberg (San Diego, California); John Rockway (San Diego, California); Mitchell Lerner (San Diego, California); Israel Perez (San Diego, California); Nicholas Lumsden (Escondido, California) |
ABSTRACT | A system includes a very low frequency (VLF) antenna connected to a circuit that has a high pass filter and a low pass filter. The circuit is configured for noise reduction and frequency localization of detected VLF signals. A receiver is configured to receive filtered VLF signals output by the circuit and to separate desired signals for processing. A display is configured to provide a user with visual feedback based at least in part on an even signature extracted by a digital signal processor (DSP). |
FILED | Wednesday, January 09, 2019 |
APPL NO | 16/243830 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/02 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) G01S 5/0215 (20130101) G01S 7/288 (20130101) G01S 2007/2883 (20130101) Electric Digital Data Processing G06F 17/142 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/093 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666307 | Wang |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Xiao-Yu Wang (Watertown, Massachusetts) |
ABSTRACT | A nonlinear compensator is provided to include a decomposition circuit and a plurality of filter elements. The decomposition circuit has a nonlinear frequency response characteristic and the decomposition circuit is configured to receive an input signal and decompose the input signal into decomposed signals corresponding to positive and negative frequency signal components of the input signal. Each of the plurality of filter elements is configured to receive at least portions of the decomposed signals and apply filter element characteristics to the decomposed signals with the filter element characteristics that are matched to the nonlinear frequency response of the decomposition circuit. |
FILED | Friday, July 20, 2018 |
APPL NO | 16/041060 |
ART UNIT | 2633 — Digital Communications |
CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/0261 (20130101) H03H 21/0012 (20130101) Coding; Decoding; Code Conversion in General H03M 1/12 (20130101) H03M 1/0626 (20130101) H03M 1/1033 (20130101) Transmission H04B 1/10 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03261 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666348 | Legare |
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FUNDED BY |
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APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | David J. Legare (Ava, New York) |
ABSTRACT | An apparatus, system, and method for a receive function in a phased array including an M by N array of antenna elements, where M and N are the number of rows and columns, respectively, in the array of antenna elements. Each antenna element is provided with a combiner. The phased array apparatus and system includes M row beam-formers plus N column beam-formers. The row beam-formers supply a progressively phase-shifted carrier signal to the combiners where the signal received by the corresponding antenna element is combined with a phase-shifted carrier signal. The outputs of the combiners in each column of antenna elements is sent to a corresponding column beam-former. The outputs of the column beam-formers are combined to recover the signal that is desired to be received. |
FILED | Monday, January 07, 2019 |
APPL NO | 16/240985 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/38 (20130101) H01Q 21/22 (20130101) Transmission H04B 7/0885 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666677 | Casey et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Will Casey (Columbia, Michigan); Bhubaneswar Mishra (Great Neck, New York) |
ABSTRACT | An exemplary system method, and computer-accessible medium for initiating a protocol(s) can be provided, which can include, for example, generating a digitally encrypted perishable object(s), distributing the digitally encrypted perishable object(s) to a cyber-physical entity(s), determining if the cyber-physical entity(s) has received the digitally encrypted perishable object(s), and initiating at a predetermined protocol(s) based on the determination. |
FILED | Wednesday, September 23, 2015 |
APPL NO | 14/862808 |
ART UNIT | 2433 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 9/3271 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US D885422 | Burnett et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Gregory M Burnett (Dayton, Ohio); Isaiah L Bragg (Xenia, Ohio); Noah W Bragg (Beavercreek, Ohio); Jared S Dewey (Tucson, Arizona); Matthew R. Weber (Beavercreek, Ohio) |
ABSTRACT | |
FILED | Friday, February 08, 2019 |
APPL NO | 29/679652 |
ART UNIT | 2916 — Design |
CURRENT CPC | Recording, communication, or information retrieval equipment D14/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D885423 | Burnett et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Gregory M Burnett (Dayton, Ohio); Isaiah L Bragg (Xenia, Ohio); Noah W Bragg (Beavercreek, Ohio); Matthew R. Weber (Beavercreek, Ohio); Jared S Dewey (Tucson, Arizona) |
ABSTRACT | |
FILED | Friday, February 08, 2019 |
APPL NO | 29/679659 |
ART UNIT | 2916 — Design |
CURRENT CPC | Recording, communication, or information retrieval equipment D14/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D885424 | Burnett et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Gregory M Burnett (Dayton, Ohio); Isaiah L Bragg (Xenia, Ohio); Noah W Bragg (Beavercreek, Ohio); Matthew R. Weber (Beavercreek, Ohio); Jared S Dewey (Tucson, Arizona) |
ABSTRACT | |
FILED | Tuesday, April 02, 2019 |
APPL NO | 29/686058 |
ART UNIT | 2916 — Design |
CURRENT CPC | Recording, communication, or information retrieval equipment D14/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 10660340 | Labbe et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Jessy L. Labbe (Oak Ridge, Tennessee); Wellington Muchero (Oak Ridge, Tennessee); Cyd Elizabeth Hamilton (Oak Ridge, Tennessee); Dale A. Pelletier (Oak Ridge, Tennessee) |
ABSTRACT | The present disclosure provides agricultural compositions and methods of using these compositions to increase plant growth, pathogen resistance and drought tolerance. The agricultural compositions disclosed herein comprise mixtures of mutualistic beneficial fungi such as Laccaria bicolor and Piriformispora indica, and bacterial strains of Pseudomonas. |
FILED | Wednesday, October 26, 2016 |
APPL NO | 15/334793 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) A01N 63/27 (20200101) A01N 63/27 (20200101) A01N 63/30 (20200101) Original (OR) Class A01N 63/30 (20200101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/39 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10660874 | Bugni et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Timothy Scott Bugni (Madison, Wisconsin); Thomas Philip Wyche (Chelsea, Massachusetts); Douglas R. Braun (Mount Horeb, Wisconsin); Jeffrey S. Piotrowski (Madison, Wisconsin); Nasia Safdar (Madison, Wisconsin) |
ABSTRACT | An isolated or synthesized compound of Formula I and salts thereof are provided. A compound isolated from Actinomadura and having a chemical formula of C38H60O12 is also provided. Compositions including the compounds and methods of using the compounds to treat bacterial infections including gram positive infections such as C. difficile are also disclosed. |
FILED | Wednesday, October 28, 2015 |
APPL NO | 15/522713 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661339 | Heidloff et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Andrew J. Heidloff (West Des Moines, Iowa); Joel R. Rieken (Nevada, Iowa); Iver E. Anderson (Ames, Iowa) |
ABSTRACT | A method for gas atomization of a titanium alloy, nickel alloy, or other alumina (Al2O3)-forming alloy wherein the atomized particles are exposed as they solidify and cool in a very short time to multiple gaseous reactive agents for the in-situ formation of a passivation reaction film on the atomized particles wherein the reaction film retains a precursor halogen alloying element that is subsequently introduced into a microstructure formed by subsequent thermally processing of the atomized particles to improve oxidation resistance. |
FILED | Monday, November 06, 2017 |
APPL NO | 15/732398 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Original (OR) Class B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 1/02 (20130101) B22F 3/14 (20130101) B22F 3/15 (20130101) B22F 3/225 (20130101) B22F 3/1055 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 9/082 (20130101) B22F 2003/208 (20130101) B22F 2003/1051 (20130101) B22F 2009/0844 (20130101) B22F 2201/00 (20130101) B22F 2201/03 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661502 | Green |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
INVENTOR(S) | Nicholas Green (Lees Summit, Missouri) |
ABSTRACT | An additive manufacturing system and method for forming a part of dissimilar materials. The additive manufacturing system may include a build platform, a recoater for dispensing build powder onto the build platform, an energy source, a foil feed assembly, and a controller for controlling actuation of these components. The method of forming the part may include the steps of depositing a layer of build powder onto the build platform surface, melting selected portions of the layer of build powder, applying a sheet of foil over the layer of build powder, melting selected portions of the sheet of foil onto the layer of build powder, removing the sheet of foil from the layer of build powder, and then lowering the build platform surface to prepare for deposition of a next layer of the build powder. These steps are then repeated one or more times, thereby forming the part. |
FILED | Tuesday, December 08, 2015 |
APPL NO | 14/962295 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/141 (20170801) Original (OR) Class B29C 64/147 (20170801) B29C 64/153 (20170801) B29C 64/218 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661549 | Jackson et al. |
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FUNDED BY |
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APPLICANT(S) | Julie A. Jackson (Livermore, California); Eric Duoss (Dublin, California); Alexandra Golobic (Oakland, California); Mark Christian Messner (Tracy, California); Christopher Spadaccini (Oakland, California); Kenneth J. Loh (San Diego, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the Univeristy of California (Oakland, California) |
INVENTOR(S) | Julie A. Jackson (Livermore, California); Eric Duoss (Dublin, California); Alexandra Golobic (Oakland, California); Mark Christian Messner (Tracy, California); Christopher Spadaccini (Oakland, California); Kenneth J. Loh (San Diego, California) |
ABSTRACT | The present disclosure relates to a method of forming an energy absorbing three dimensional (3D) structure. The method involves forming an outer shell for the 3D structure from a shell material, the outer shell having a void forming a core volume. The method also involves filling the core volume with a transformative liquid. When the 3D structure is fully formed, the transformative liquid is encapsulated within the outer shell and provides enhanced energy absorbing properties to the 3D structure. |
FILED | Wednesday, August 17, 2016 |
APPL NO | 15/239306 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0008 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Original (OR) Class Springs; Shock-absorbers; Means for Damping Vibration F16F 9/532 (20130101) F16F 9/535 (20130101) F16F 2226/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661908 | Boreyko et al. |
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FUNDED BY |
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APPLICANT(S) | Jonathan B. Boreyko (Christiansburg, Virginia); Saurabh Nath (Blacksburg, Virginia); Caitlin Bisbano (Blacksburg, Virginia); Grady J. Iliff (Hamilton, Virginia); Ryan Hansen (Manhattan, Kansas); C. Patrick Collier (Oak Ridge, Tennessee) |
ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia); UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Jonathan B. Boreyko (Christiansburg, Virginia); Saurabh Nath (Blacksburg, Virginia); Caitlin Bisbano (Blacksburg, Virginia); Grady J. Iliff (Hamilton, Virginia); Ryan Hansen (Manhattan, Kansas); C. Patrick Collier (Oak Ridge, Tennessee) |
ABSTRACT | A method and device for reducing ice and frost on a surface comprising a wettable pattern on a surface. The pattern is wetted with water which is frozen into ice to create overlapping hygroscopic that cover the surface. |
FILED | Wednesday, October 04, 2017 |
APPL NO | 15/724995 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/38 (20130101) B05D 7/24 (20130101) B05D 2350/33 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 15/06 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 47/006 (20130101) Producing, Working or Handling Ice F25C 1/06 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 21/04 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 19/02 (20130101) F28F 19/006 (20130101) F28F 2245/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662065 | Steinhardt et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Paul J. Steinhardt (Princeton, New Jersey); Salvatore Torquato (Princeton, New Jersey); Miroslav Hejna (Princeton, New Jersey) |
ABSTRACT | This invention is in the field of physical chemistry and relates to novel hyperuniform and nearly hyperuniform random network materials and methods of making said materials. Methods are described for controlling or altering the band gap of a material, and in particular commercially useful materials such as amorphous silicon. These methods can be exploited in the design of semiconductors, transistors, diodes, solar cells and the like. |
FILED | Friday, April 27, 2018 |
APPL NO | 15/965206 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/02 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/03762 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/548 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662082 | Subban et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Chinmayee V. Subban (Hayward, California); Ashok J. Gadgil (El Cerrito, California); Robert Kostecki (Lafayette, California); Guoying Chen (Oakland, California) |
ABSTRACT | The present disclosure provides a device comprising or configured to comprise composite resin electrodes. Further provided are methods of using the device for selectively removing dissolved ions from water. |
FILED | Friday, December 15, 2017 |
APPL NO | 15/843712 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) Original (OR) Class C02F 1/4604 (20130101) C02F 1/4691 (20130101) C02F 1/46109 (20130101) C02F 2001/46138 (20130101) C02F 2001/46157 (20130101) C02F 2101/14 (20130101) C02F 2101/103 (20130101) C02F 2103/06 (20130101) C02F 2103/08 (20130101) C02F 2103/10 (20130101) C02F 2103/32 (20130101) C02F 2201/4613 (20130101) C02F 2303/16 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662289 | Beckham et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Gregg Tyler Beckham (Golden, Colorado); Nicholas Rorrer (Golden, Colorado); Derek Richard Vardon (Lakewood, Colorado) |
ABSTRACT | The present disclosure relates to a polymer that includes a first repeat unit having the structure where m is between 1 and 1,000, R1 includes a first organic group, and R2 includes a second organic group. |
FILED | Monday, April 02, 2018 |
APPL NO | 15/942703 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/28 (20130101) C08G 69/265 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662456 | Shasky et al. |
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FUNDED BY |
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APPLICANT(S) | Novozymes A/S (Bagsvaerd, Denmark) |
ASSIGNEE(S) | Novozymes A/s (Bagsvaerd, Germany) |
INVENTOR(S) | Jeffrey Shasky (Davis, California); Suchindra Maiyuran (Gold River, California); Amanda Fischer (Davis, California) |
ABSTRACT | The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions. |
FILED | Wednesday, February 06, 2019 |
APPL NO | 16/268922 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/38 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01037 (20130101) C12Y 302/01091 (20130101) C12Y 302/01176 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662509 | Balachandran et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Uthamalingam Balachandran (Willowbrook, Illinois); Beihai Ma (Naperville, Illinois); Stephen E. Dorris (Lagrange Park, Illinois) |
ABSTRACT | A method for making covetic metal-carbon composites or compositions by electron beam melt heating under vacuum (pressure <10−3 Torr) is described herein. This fabrication method is advantageous, in that it provides oxygen-free covetic materials in a process that allows precise control of the composition of the covetic material to be produced. The method described herein also can be applied to produce multi-element-carbon composites within a metal or alloy matrix, including high melting temperature materials such as ceramic particles or prefabricated nano- or micro-structures, such as carbon nanotubes or graphene compounds. The covetic reaction between metal and carbon takes place under the influence of flowing electrons through the melted metal-carbon precursor. This process creates strong bonding between nanocarbon structure and the metal elements in the melt. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/261205 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 21/005 (20130101) B22D 23/06 (20130101) B22D 27/15 (20130101) B22D 29/00 (20130101) B22D 30/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2202/06 (20130101) B22F 2202/11 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/02 (20130101) C22C 1/05 (20130101) C22C 26/00 (20130101) C22C 32/0084 (20130101) Original (OR) Class C22C 2001/1047 (20130101) C22C 2001/1047 (20130101) C22C 2026/002 (20130101) Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 17/0016 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/12 (20130101) F27D 13/00 (20130101) F27D 2007/066 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662548 | Mackintosh et al. |
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FUNDED BY |
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APPLICANT(S) | Leading Edge Crystal Technologies, Inc. (Gloucester, Massachusetts) |
ASSIGNEE(S) | Leading Edge Crystal Technologies, Inc. (Gloucester, Massachusetts) |
INVENTOR(S) | Brian H. Mackintosh (Concord, Massachusetts); Peter L. Kellerman (Essex, Massachusetts); Dawei Sun (Nashua, New Hampshire) |
ABSTRACT | An apparatus for growing a crystalline sheet from a melt includes a cold block assembly. The cold block assembly may include a cold block and a shield surrounding the cold block and being at an elevated temperature with respect to that of the cold block, the shield defining an opening disposed along a surface of the cold block proximate a melt surface that defines a cold area comprising a width along a first direction of the cold block, the cold area operable to provide localized cooling of a region of the melt surface proximate the cold block. The apparatus may further include a crystal puller arranged to draw a crystalline seed in a direction perpendicular to the first direction when the cold block assembly is disposed proximate the melt surface. |
FILED | Friday, March 16, 2018 |
APPL NO | 15/923360 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 15/06 (20130101) C30B 15/14 (20130101) Original (OR) Class C30B 29/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 117/1008 (20150115) Y10T 117/1044 (20150115) Y10T 117/1048 (20150115) Y10T 117/1068 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662550 | Zeng et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Diamond Technologies, Inc. (Romeoville, Illinois) |
ASSIGNEE(S) | JOHN CRANE INC. (Chicago, Illinois) |
INVENTOR(S) | Hongjun Zeng (Naperville, Illinois); Nicolaie A. Moldovan (Plainfield, Illinois) |
ABSTRACT | A method for forming diamond nanostructures with large specific area can include forming porous diamond nanostructures by means of selectively etching sp2-bonded carbon and partially removing sp3-bonded carbon in nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD® diamond). The diamond nanostructures achieved from the disclosed method can include a long shaft surrounded by a school of barbs. The nanostructure can provide a significantly larger surface area than diamond without such a nanostructure and its fabrication provides relative ease of manufacture compared to traditional techniques. |
FILED | Thursday, November 02, 2017 |
APPL NO | 15/801759 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/26 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/30 (20130101) C01P 2006/12 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662552 | Chen |
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FUNDED BY |
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APPLICANT(S) | Xing Chen (Plainfield, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Xing Chen (Plainfield, Illinois) |
ABSTRACT | The invention provides a method for producing fibers, the method having the steps of producing electrospun fiber; and directing the fiber to a plurality of targets, whereby only one of the targets is grounded at any one time. Also provided is a system for producing anisotropic fibers having a reservoir of electrospun fiber constituent' wherein an egress point of the reservoir is electrically charged; a plurality of electrodes opposed to the egress point, wherein only one of the electrodes is grounded at any one time while the remaining electrodes are at an initial floating voltage state; and a target substrate disposed between the egress point and the plurality of electrodes. |
FILED | Thursday, August 18, 2016 |
APPL NO | 15/240168 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662823 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | Modine Manufacturing Company (Racine, Wisconsin); Cummins Inc. (, None) |
ASSIGNEE(S) | MODINE MANUFACTURING COMPANY (Racine, Wisconsin); CUMMINS INC. (Columbus, Indiana) |
INVENTOR(S) | Gregory Gerald Hughes (Milwaukee, Wisconsin); Michael J. Reinke (Franklin, Wisconsin); Tony Rousseau (Racine, Wisconsin); Timothy C. Ernst (Columbus, Indiana); James Zigan (Versailles, Indiana); Christopher Nelson (Columbus, Indiana) |
ABSTRACT | A power generation system having a combustion engine with a Rankine bottoming cycle, the system including a first flow path for a process fluid and a second flow path for a working fluid, and a heat exchanger arranged along both the first and the second flow paths to transfer waste heat from the process fluid to the working fluid. The heat exchanger includes a first flow conduit being bounded by a first wall section and configured to convey the process fluid, a second flow conduit to convey the working fluid, the second flow conduit being bounded by a second wall section spaced apart from the first wall section to define a gap therebetween, and a thermally conductive structure arranged within the gap and joined to the first and second wall sections to transfer heat therebetween, the gap being fluidly isolated from both the process fluid and the working fluid. |
FILED | Tuesday, September 24, 2013 |
APPL NO | 14/430796 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/16 (20130101) F01K 23/10 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/0025 (20130101) F28D 9/00 (20130101) F28D 15/00 (20130101) F28D 21/0003 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 3/005 (20130101) F28F 3/027 (20130101) F28F 9/001 (20130101) F28F 9/0246 (20130101) F28F 2265/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662918 | Thresher et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Robert Thresher (Golden, Colorado); Michael Lawson (Golden, Colorado); Nathan Tom (Golden, Colorado); Jason Cotrell (Golden, Colorado); Yi-Hsiang Yu (Golden, Colorado); Alan Wright (Golden, Colorado) |
ABSTRACT | Described herein are wave energy conversion systems including actuated geometry components. An example system may include at least one body portion configured to transfer wave energy to a power take off device, and at least one actuated geometry component that is connected to the at least one body portion, the at least one actuated geometry component operable to modify a geometric profile of the system. |
FILED | Thursday, August 02, 2018 |
APPL NO | 16/053327 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Machines or Engines for Liquids F03B 13/16 (20130101) Original (OR) Class F03B 13/20 (20130101) F03B 13/142 (20130101) F03B 13/182 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2250/00 (20130101) F05B 2250/02 (20130101) F05B 2270/20 (20130101) F05B 2270/30 (20130101) F05B 2270/324 (20130101) F05B 2270/325 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/32 (20130101) Y02E 10/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663040 | Shu et al. |
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FUNDED BY |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Deming Shu (Darien, Illinois); Barry Lai (Woodridge, Illinois); Steven P. Kearney (Lombard, Illinois); Jayson W. Anton (Chicago, Illinois); Wenjun Liu (Bolingbrook, Illinois); Jorg M. Maser (Oak Park, Illinois); Christian Roehrig (Plainfield, Illinois); Jonathan Z. Tischler (Lisle, Illinois) |
ABSTRACT | An enhanced method and precision nanopositioning apparatus for implementing enhanced nanopositioning performance is provided. The nanopositioning apparatus includes a vertical linear nanopositioning flexure stage and a horizontal linear nanopositioning flexure stage. The vertical linear nanopositioning flexure stage includes a stage base, a symmetrically configured flexure linear guiding mechanism with precision motion enhancement structure, and a stage carriage. The horizontal linear nanopositioning flexure stage is mounted on the stage carriage of the vertical linear nanopositioning flexure stage, and includes a middle-bar relative position control mechanism to enhance the stiffness of a flexure linear guiding mechanism. |
FILED | Thursday, July 27, 2017 |
APPL NO | 15/662086 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Gearing F16H 21/04 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 2/028 (20130101) H02N 2/043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663228 | Birkmire et al. |
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FUNDED BY |
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APPLICANT(S) | JLN Solar, Inc. (Mill Valley, California) |
ASSIGNEE(S) | JLN SOLAR, INC. (Mill Valley, California) |
INVENTOR(S) | Robert W. Birkmire (Newark, Delaware); Gregory M. Hanket (Newark, Delaware) |
ABSTRACT | A thermal evaporation sources are described. These thermal evaporation sources include a crucible configured to contain a volume of evaporant and a vapor space above the evaporant. |
FILED | Monday, July 10, 2017 |
APPL NO | 15/645927 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/243 (20130101) C23C 14/543 (20130101) Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 14/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663367 | Dittberner et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Matthias Dittberner (Yorktown Heights, New York); Levente Klein (Tuckahoe, New York) |
ABSTRACT | A method, a system and an apparatus for adaptively sensing a gas leak. The method includes: obtaining wind data from a wind sensor, identifying at least one wireless mote in a plurality of wireless motes that is most likely to detect a gas plume from the wind data, activating the identified at least one wireless mote to trigger measuring gas concentration of the gas plume, and identifying the location of the gas leak if the gas concentration is above a predetermined threshold. Also included is a system for adaptively sensing a gas leak having a wind sensor, a plurality of wireless motes and a server in communication therewith. An apparatus for adaptively sensing a gas leak in an industrial site is also provided. |
FILED | Friday, July 28, 2017 |
APPL NO | 15/662730 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/16 (20130101) Original (OR) Class G01M 3/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 27/045 (20130101) G01N 33/0031 (20130101) Meteorology G01W 1/00 (20130101) G01W 2001/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663662 | Gehl et al. |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Michael Gehl (Albuquerque, New Mexico); Christopher DeRose (Victor, New York) |
ABSTRACT | A hybrid spiral waveguide geometry is proposed that exhibits essentially zero curvature (i.e., infinite bend radius) at the center of the spiral (similar to a Fermat spiral), with the curvature then increasing in value as the spiral moves outward. Advantageously, as the spiral moves away from the center, the spacing between adjacent waveguides quickly approaches a constant value (similar to an Archimedean spiral). This hybrid spiral structure has been found to allow for a high density waveguide to be created with lower loss and requiring a smaller size than many conventional spiral configurations and finds use in optical delay lines, amplifiers and arrayed waveguide gratings. |
FILED | Monday, April 29, 2019 |
APPL NO | 16/397624 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) G02B 6/125 (20130101) Original (OR) Class G02B 6/12009 (20130101) G02B 6/12033 (20130101) G02B 2006/12061 (20130101) G02B 2006/12085 (20130101) G02B 2006/12097 (20130101) G02B 2006/12142 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/0147 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663932 | Pratt et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Richard M. Pratt (Richland, Washington); Donald J. Hammerstrom (West Richland, Washington); Michael C. W. Kintner-Meyer (Richland, Washington); Francis K. Tuffner (Richland, Washington) |
ABSTRACT | Disclosed herein are representative embodiments of methods, apparatus, and systems for charging and discharging an energy storage device connected to an electrical power distribution system. In one exemplary embodiment, a controller monitors electrical characteristics of an electrical power distribution system and provides an output to a bi-directional charger causing the charger to charge or discharge an energy storage device (e.g., a battery in a plug-in hybrid electric vehicle (PHEV)). The controller can help stabilize the electrical power distribution system by increasing the charging rate when there is excess power in the electrical power distribution system (e.g., when the frequency of an AC power grid exceeds an average value), or by discharging power from the energy storage device to stabilize the grid when there is a shortage of power in the electrical power distribution system (e.g., when the frequency of an AC power grid is below an average value). |
FILED | Thursday, April 13, 2017 |
APPL NO | 15/487310 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/16 (20190201) B60L 53/30 (20190201) B60L 53/51 (20190201) B60L 53/53 (20190201) B60L 53/56 (20190201) B60L 53/63 (20190201) B60L 53/65 (20190201) B60L 53/305 (20190201) B60L 55/00 (20190201) B60L 58/13 (20190201) B60L 2210/30 (20130101) B60L 2210/40 (20130101) B60L 2240/70 (20130101) B60L 2240/80 (20130101) B60L 2250/12 (20130101) B60L 2260/58 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/02 (20130101) Original (OR) Class G05B 15/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/44 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/24 (20130101) H02J 3/32 (20130101) H02J 7/0047 (20130101) H02J 7/0068 (20130101) H02J 13/0013 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/2607 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/721 (20130101) Y02E 60/722 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/705 (20130101) Y02T 10/7005 (20130101) Y02T 10/7044 (20130101) Y02T 10/7088 (20130101) Y02T 10/7094 (20130101) Y02T 10/7241 (20130101) Y02T 10/7291 (20130101) Y02T 90/14 (20130101) Y02T 90/16 (20130101) Y02T 90/121 (20130101) Y02T 90/127 (20130101) Y02T 90/128 (20130101) Y02T 90/163 (20130101) Y02T 90/168 (20130101) Y02T 90/169 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/14 (20130101) Y04S 10/126 (20130101) Y04S 30/12 (20130101) Y04S 30/14 (20130101) Y04S 40/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/527 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665396 | Ruther et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Rose E. Ruther (Oak Ridge, Tennessee); Frank M. Delnick (Maryville, Tennessee); Jagjit Nanda (Knoxville, Tennessee) |
ABSTRACT | A supercapacitor according to the present invention includes a negative carbon-comprising electrode which does not intercalate sodium, and a positive carbon-comprising electrode. An electrolyte composition comprises sodium hexafluorophosphate and a non-aqueous solvent comprising at least one selected from the group consisting of ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, and tetraethylene glycol dimethyl ether. The supercapacitor has an electrochemical voltage window of from +0.0 V to 3.5 V (full cell voltage). The electrolyte has an electrochemical voltage window of from +0.05 V to 3.9 V vs. Na/Na+. A method of making and a method of operating a supercapacitor is also disclosed. |
FILED | Friday, January 17, 2020 |
APPL NO | 16/746503 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/06 (20130101) H01G 11/24 (20130101) H01G 11/32 (20130101) H01G 11/38 (20130101) H01G 11/60 (20130101) Original (OR) Class H01G 11/62 (20130101) H01G 11/84 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665402 | Sommerer et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Timothy John Sommerer (Ballston Spa, New York); Joseph Darryl Michael (Delmar, New York) |
ABSTRACT | A high voltage gas switch includes a gas-tight housing containing an ionizable gas at a preselected gas pressure. The gas switch includes a gas-tight housing containing an ionizable gas at a gas pressure selected based upon a Paschen curve for the ionizable gas, where the Paschen curve plots breakdown voltages of the ionizable gas as a function of gas pressure multiplied by grid-to-anode distance, and where values of gas pressure multiplied by grid-to-anode distance increase over at least a portion of the Paschen curve in conjunction with increasing breakdown voltages. The gas switch also includes an anode disposed within the gas-tight housing, a cathode disposed within the gas-tight housing, and a control grid positioned between the anode and the cathode, where the control grid is spaced apart from the anode by a grid-to-anode distance selected based upon a desired operating voltage. |
FILED | Thursday, February 08, 2018 |
APPL NO | 15/891539 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/025 (20130101) Original (OR) Class H01H 33/53 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 17/06 (20130101) H01J 17/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665443 | Ibrahim et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Yehia M Ibrahim (Richland, Washington); Richard D. Smith (Richland, Washington) |
ABSTRACT | An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation direction, each opposing electrode arrangement including an arrangement of RF electrodes situated to receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes of the arrangement of RF electrodes so as to provide the confining of ions between the first pair of opposing electrode arrangements, and a second pair of opposing electrode arrangements that confine the ions between the second pair in the confinement volume inwardly laterally in a second confinement direction that complements the first confinement direction, each opposing electrode arrangement of the second pair including an arrangement of RF electrodes that receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes. |
FILED | Thursday, February 28, 2019 |
APPL NO | 16/289216 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/062 (20130101) H01J 49/063 (20130101) H01J 49/065 (20130101) H01J 49/0095 (20130101) Original (OR) Class H01J 49/4235 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665447 | Jordan et al. |
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FUNDED BY |
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APPLICANT(S) | BNNT, LLC (Newport News, Virginia); JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
ASSIGNEE(S) | BNNT, LLC (Newport News, Virginia); Jefferson Science Associates, LLC (Newport News, Virginia) |
INVENTOR(S) | Kevin C. Jordan (Newport News, Virginia); Thomas G. Dushatinski (Chesapeake, Virginia); Michael W. Smith (Newport News, Virginia); Jonathan C. Stevens (Williamsburg, Virginia); R. Roy Whitney (Newport News, Virginia) |
ABSTRACT | Transition radiation from nanotubes, nanosheets, and nanoparticles and in particular, boron nitride nanomaterials, can be utilized for the generation of light. Wavelengths of light of interest for microchip lithography, including 13.5 nm (91.8 eV) and 6.7 nm (185 eV), can be generated at useful intensities, by transition radiation light sources. Light useful for monitoring relativistic charged particle beam characteristics such as spatial distribution and intensity can be generated. |
FILED | Wednesday, March 06, 2019 |
APPL NO | 16/294015 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 63/02 (20130101) H01J 63/06 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/00 (20130101) H01S 3/169 (20130101) X-ray Technique H05G 2/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) H05H 9/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665803 | Rand et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
ASSIGNEE(S) | THE TRUSTEEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Barry P. Rand (Princeton, New Jersey); YunHui L. Lin (West Windsor, New Jersey) |
ABSTRACT | In one aspect, solid-state organic intermediate-band photovoltaic devices are provided. A solid-state organic intermediate-band photovoltaic device, in some embodiments, comprises an organic electron donor and an organic electron acceptor, wherein the organic electron donor comprises a singlet energy level separated from a triplet energy level by an energy gap. The device also comprises a triplet sensitizer comprising singlet and triplet energy levels falling within the singlet-triplet energy gap of the electron donor. |
FILED | Friday, April 21, 2017 |
APPL NO | 16/094980 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/04 (20130101) H01L 33/06 (20130101) H01L 51/0035 (20130101) H01L 51/0037 (20130101) H01L 51/0046 (20130101) H01L 51/50 (20130101) H01L 51/0056 (20130101) H01L 51/0057 (20130101) H01L 51/0068 (20130101) H01L 51/0072 (20130101) H01L 51/0087 (20130101) H01L 51/4246 (20130101) Original (OR) Class H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666051 | Venkatasubramanian et al. |
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FUNDED BY |
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APPLICANT(S) | Washington State University (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | Vaithianathan Venkatasubramanian (Pullman, Washington); Ebrahim Rezaei (Pullman, Washington) |
ABSTRACT | Electrical circuit control techniques in power systems are disclosed herein. In one embodiment, a supervisory computer in the power system can be configured to fit phasor measurement data from phasor measurement units into a Gaussian distribution with a corresponding Gaussian confidence level. When the Gaussian confidence level of the fitted Gaussian distribution is above a Gaussian confidence threshold, the supervisory computer can be configured to perform an ambient analysis on the received phasor measurement data to determine an operating characteristic of the power system. The supervisory computer can then automatically applying at least one electrical circuit control action to the power system in response to the determined operating characteristic. |
FILED | Wednesday, June 27, 2018 |
APPL NO | 16/020781 |
ART UNIT | 2185 — Computer Architecture and I/O |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2513 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 9/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/24 (20130101) Original (OR) Class H02J 3/1835 (20130101) H02J 3/1878 (20130101) H02J 13/0017 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/728 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/265 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666054 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
INVENTOR(S) | David G. Wilson (Tijeras, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Wayne W. Weaver (Hancock, Michigan); Steven F. Glover (Albuquerque, New Mexico) |
ABSTRACT | A method for designing feedforward and feedback controllers for integration of stochastic sources and loads into a nonlinear networked AC/DC microgrid system is provided. A reduced order model for general networked AC/DC microgrid systems is suitable for HSSPFC control design. A simple feedforward steady state solution is utilized for the feedforward controls block. Feedback control laws are provided for the energy storage systems. A HSSPFC controller design is implemented that incorporates energy storage systems that provides static and dynamic stability conditions for both the DC random stochastic input side and the AC random stochastic load side. Transient performance was investigated for the feedforward/feedback control case. Numerical simulations were performed and provided power and energy storage profile requirements for the networked AC/DC microgrid system overall performance. The HSSPFC design can be implemented in the Matlab/Simulink environment that is compatible with real time simulation/controllers. |
FILED | Thursday, May 17, 2018 |
APPL NO | 15/982850 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/30 (20130101) H02J 3/32 (20130101) H02J 3/381 (20130101) H02J 3/382 (20130101) Original (OR) Class H02J 7/34 (20130101) H02J 2203/20 (20200101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) Y02E 10/563 (20130101) Y02E 10/763 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666222 | Eichenfield et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Matt Eichenfield (Albuquerque, New Mexico); Roy Olsson (Arlington, Virginia); Anna Tauke-Pedretti (Albuquerque, New Mexico); Andrew Leenheer (Albuquerque, New Mexico); Aleem Siddiqui (Albuquerque, New Mexico); Thomas A. Friedmann (Albuquerque, New Mexico) |
ABSTRACT | An amplifying radiofrequency device includes a piezoelectric film and a semiconductor amplifier layer. The piezoelectric film is conformed as an acoustic waveguide. The piezoelectric film has a principal acoustic propagation direction parallel to the principal conduction direction of the amplifier layer. Interdigitated transducers are positioned on the piezoelectric film to respectively launch an acoustic wave in response to an input RF signal, and transduce the acoustic wave back to an output RF signal. There is a distance of less than the acoustic wavelength between the semiconductor amplifier layer and the piezoelectric film. The piezoelectric film has a thickness of less than the acoustic wavelength. According to a method for making such a device, a stack of III-V layers is epitaxially grown on a III-V substrate, wherein the stack comprises a first etch stop layer, a second etch stop layer, an amplifier layer, and a contact layer. The stack is bonded to a lithium niobate film. The III-V substrate is removed by etching down to the first etch stop layer. Deposition windows are opened by etching from the first etch stop layer down to the contact layer. Metal contact electrodes are deposited in the deposition windows. |
FILED | Thursday, September 28, 2017 |
APPL NO | 15/718817 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/047 (20130101) H01L 41/313 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/08 (20130101) H03H 9/058 (20130101) H03H 9/02559 (20130101) H03H 9/02566 (20130101) H03H 9/02976 (20130101) Original (OR) Class H03H 9/14514 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
10660850 — Compositions and methods of making brittle-matrix particles through blister pack freezing
US 10660850 | Johnston et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Keith P. Johnston (Austin, Texas); Joshua Engstrom (Spotswood, New Jersey); Jasmine Rowe (Austin, Texas); Alan B. Watts (Plainsboro, New Jersey); Robert O. Williams, III (Austin, Texas) |
ABSTRACT | The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. |
FILED | Thursday, August 29, 2019 |
APPL NO | 16/555165 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) Original (OR) Class A61K 9/0075 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
10661180 — Method and system modeling social identity in digital media with dynamic group membership
US 10661180 | Harrell, Jr. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Douglas Alan Harrell, Jr. (Cambridge, Massachusetts) |
ABSTRACT | A digital media system models social categories of a virtual identity. The system, defines a plurality of modeling categories according to the virtual identity and models a degree of a membership in a category for a member of the category. Each category has a feature shared in varying degrees by one or more members of the category. The system simulates changes to the membership and determines a naturalization trajectory having a change of the degree of membership in a category over time of the virtual identity. The degree of membership includes a gradient value in a category feature and an interface configured to represent a category membership that dynamically changes as category membership changes. |
FILED | Thursday, January 10, 2019 |
APPL NO | 16/244514 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/55 (20140902) A63F 13/58 (20140902) A63F 13/79 (20140902) Original (OR) Class A63F 13/795 (20140902) A63F 13/822 (20140902) A63F 2300/65 (20130101) A63F 2300/807 (20130101) A63F 2300/5546 (20130101) A63F 2300/5553 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 16/335 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/01 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/32 (20130101) H04L 67/306 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661251 | Gilliland, III et al. |
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FUNDED BY |
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APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia) |
ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
INVENTOR(S) | Stanley Eugene Gilliland, III (North Chesterfield, Virginia); Bernard Frank Gupton (Richmond, Virginia); Caleb June Kong (Richmond, Virginia); Brian Raymond Clark (Richmond, Virginia) |
ABSTRACT | High activity metal nanoparticle catalysts, such as Pd or Pt nanoparticle catalysts, are provided. Adsorption of metal precursors such as Pd or Pt precursors onto carbon based materials such as graphene followed by solventless (or low-solvent) microwave irradiation at ambient conditions results in the formation of catalysts in which metal nanoparticles are supported on i) the surface of the carbon based materials and ii) in/on/within defects/holes in the carbon based materials. |
FILED | Tuesday, November 27, 2018 |
APPL NO | 16/201222 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/42 (20130101) Original (OR) Class B01J 23/44 (20130101) B01J 35/002 (20130101) B01J 35/006 (20130101) B01J 35/0013 (20130101) B01J 37/16 (20130101) B01J 37/035 (20130101) B01J 37/0201 (20130101) B01J 37/0236 (20130101) B01J 37/346 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0801 (20130101) C07F 7/0829 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10661273 | Ok et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Jong G. Ok (Seoul, South Korea); Lingjie J. Guo (Ann Arbor, Michigan); Long Chen (Ann Arbor, Michigan); Ashwin Panday (Ann Arbor, Michigan) |
ABSTRACT | Methods of forming two-dimensional nanopatterns are provided. The method may comprise periodically contacting a vibrating tool comprising a patterned grating edge with a substrate along a first direction in a grating-vibrational indentation patterning process. The patterned grating edge defines a plurality of rows and a plurality of interspersed troughs. The periodic contacting creates a two dimensional array of discontinuous voids in a single-stroke across the surface of the substrate. In other aspects, a microfluidic device for selective arrangement of a microspecies or nanospecies is provided, that includes a substrate comprising a surface defining a two-dimensional pattern of microvoids or nanovoids. In yet other aspects, the present disclosure provides a method for selective arrangement of a microspecies or nanospecies on a substrate. |
FILED | Thursday, October 13, 2016 |
APPL NO | 15/293134 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2300/0893 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) B81B 2203/033 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) B81C 1/0046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662070 | Rimer et al. |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
INVENTOR(S) | Jeffrey D. Rimer (Houston, Texas); Manjesh Kumar (Houston, Texas) |
ABSTRACT | Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/μm2 or greater. |
FILED | Thursday, November 08, 2018 |
APPL NO | 16/183862 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/06 (20130101) B01J 29/035 (20130101) B01J 29/85 (20130101) B01J 29/7015 (20130101) B01J 35/002 (20130101) B01J 35/023 (20130101) B01J 35/0033 (20130101) B01J 47/00 (20130101) B01J 2229/62 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/04 (20130101) C01B 39/54 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/20 (20130101) C01P 2004/38 (20130101) C01P 2004/60 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/14 (20130101) C30B 29/34 (20130101) C30B 29/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662086 | Foster et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | John E. Foster (Ann Arbor, Michigan); Selman Mujovic (Jamaica, New York) |
ABSTRACT | A system for water purification having a water inlet being distributed into a plurality of streams defining extended dielectric barrier layers with high surface area to volume ratios and a plasma disposed between at least a pair of the plurality of water streams forming a surface plasma attachment producing radicals that treat the water via diffusion. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/577478 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/72 (20130101) C02F 1/78 (20130101) C02F 1/722 (20130101) C02F 1/4608 (20130101) Original (OR) Class C02F 2101/308 (20130101) C02F 2201/007 (20130101) C02F 2201/46 (20130101) C02F 2305/023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662295 | Maynard |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California) |
ABSTRACT | Trehalose-based hydrogels and methods of making such hydrogels are disclosed. Specifically, a method of creating a trehalose-based hydrogel, comprising the steps of: a) forming a trehalose homopolymer or co-polymer; b) preparing a cross-linker; and c) reacting the trehalose homopolymer or co-polymer with the cross-linker to form the trehalose-based hydrogel. |
FILED | Wednesday, August 12, 2015 |
APPL NO | 15/503348 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Fodder A23K 20/163 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 47/32 (20130101) A61K 47/36 (20130101) A61K 2300/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/22 (20130101) C08F 12/32 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/34 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 2325/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/96 (20130101) Enzymes C12Y 301/03026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662383 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Fanglin Chen (Irmo, South Carolina); Libin Lei (Columbia, South Carolina); Tong Liu (Columbia, South Carolina); Shumin Fang (Columbia, South Carolina) |
ABSTRACT | A method for generating hydrocarbons using a solid oxide electrolysis cell (SOEC) and a Fischer-Tropsch unit in a single microtubular reactor is described. This method can directly synthesize hydrocarbons from carbon dioxide and water. The method integrates high temperature co-electrolysis of H2O and CO2 and low temperature Fischer-Tropsch (F-T) process in a single microtubular reactor by designation of a temperature gradient along the axial length of the microtubular reactor. In practice, methods disclosed herein can provide direct conversion of CO2 to hydrocarbons for use as feedstock or energy storage. |
FILED | Friday, May 17, 2019 |
APPL NO | 16/415513 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/10 (20130101) B01J 23/78 (20130101) B01J 23/83 (20130101) Acyclic or Carbocyclic Compounds C07C 1/10 (20130101) C07C 1/12 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/34 (20130101) C10G 2/35 (20130101) Original (OR) Class C10G 2/40 (20130101) C10G 2/50 (20130101) C10G 2/332 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) C25B 9/10 (20130101) C25B 15/02 (20130101) C25B 15/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662402 | Lipkens et al. |
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FUNDED BY |
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APPLICANT(S) | FloDesign Sonics, Inc. (Wilbraham, Massachusetts) |
ASSIGNEE(S) | FloDesign Sonics, Inc. (Wilbraham, Massachusetts) |
INVENTOR(S) | Bart Lipkens (Bloomfield, Connecticut); Erik Miller (Belchertown, Massachusetts); Benjamin Ross-Johnsrud (Wilbraham, Massachusetts); Walter M. Presz, Jr. (Wilbraham, Massachusetts); Kedar Chitale (Vernon, Connecticut); Thomas J. Kennedy, III (Wilbraham, Massachusetts); Lauryn Winiarski (Agawam, Massachusetts) |
ABSTRACT | Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn. |
FILED | Tuesday, September 05, 2017 |
APPL NO | 15/696176 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 17/04 (20130101) B01D 17/06 (20130101) B01D 21/283 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0644 (20130101) Apparatus for Enzymology or Microbiology; C12M 29/10 (20130101) C12M 29/18 (20130101) C12M 33/08 (20130101) C12M 35/04 (20130101) C12M 47/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/0973 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662426 | Lynch et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Ashley Delanie Trahan (Hillsborough, North Carolina); Daniel Rodriguez (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina); Charles Bridwell Cooper (Durham, North Carolina); Ahmet Bozdag (Raleigh, North Carolina) |
ABSTRACT | This invention relates to metabolically engineered microorganisms, such as bacterial and or fungal strains, and bioprocesses utilizing such strains. These strains enable the dynamic control of metabolic pathways, which can be used to optimize production. Dynamic control over metabolism is accomplished via a combination of methodologies including but not limited to transcriptional silencing and controlled enzyme proteolysis. These microbial strains are utilized in a multi-stage bioprocess encompassing at least two stages, the first stage in which microorganisms are grown and metabolism can be optimized for microbial growth and at least one other stage in which growth can be slowed or stopped, and dynamic changes can be made to metabolism to improve the production of desired product, such as a chemical or fuel. |
FILED | Thursday, June 11, 2015 |
APPL NO | 15/317768 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/111 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2320/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662432 | Mirsky et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Ethan Mirsky (San Francisco, California); Karsten Temme (San Francisco, California); Christopher A. Voigt (Belmont, Massachusetts); Dehua Zhao (Allston, Massachusetts) |
ABSTRACT | Methods for making synthetic gene clusters are described. |
FILED | Friday, September 15, 2017 |
APPL NO | 15/706353 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/26 (20130101) C07K 14/255 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0095 (20130101) C12N 15/52 (20130101) C12N 15/63 (20130101) C12N 15/67 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class Enzymes C12Y 118/06001 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 30/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662448 | Jeffries et al. |
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FUNDED BY |
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APPLICANT(S) | Xylome Corporation (Madison, Wisconsin) |
ASSIGNEE(S) | XYLOME CORPORATION (Madison, Wisconsin) |
INVENTOR(S) | Thomas W. Jeffries (Madison, Wisconsin); David Z. Mokry (Madison, Wisconsin); Christopher H. Calvey (Madison, Wisconsin) |
ABSTRACT | Lipogenic yeasts bioengineered to overexpress genes for lipid production, and methods of use thereof. The yeasts are modified to express, constitutively express, or overexpress an acetyl-CoA carboxylase, an alpha-amylase, an ATP citrate lyase, a diacylglycerol acyltransferase, a fatty acid synthase, a glycerol kinase, a 6-phosphogluconate dehydrogenase, a glycerol-3-phosphate dehydrogenase, a malic enzyme, a fatty acyl-CoA reductase, a delta-9 acyl-CoA desaturase, a glycerol-3-phosphate acyltransferase, a lysophosphatidate acyltransferase, a glucose-6-phosphate dehydrogenase, a beta-glucosidase, a hexose transporter, a glycerol transporter, a glycoside hydrolase enzyme, an auxiliary activity family 9 enzyme, or combinations thereof. The yeasts in some cases are also modified to reduce or ablate activity of certain proteins. The methods include cultivating the yeast to convert low value soluble organic stillage byproducts into lipids suitable for biodiesel production and other higher value uses. |
FILED | Thursday, August 17, 2017 |
APPL NO | 15/679825 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 15/81 (20130101) C12N 15/1096 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 7/649 (20130101) Original (OR) Class C12P 7/6463 (20130101) C12P 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/40 (20130101) C12Q 1/48 (20130101) C12Q 1/527 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662472 | Ju et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Zengmin Li (Flushing, New York); John Robert Edwards (St. Louis, Missouri); Yasuhiro Itagaki (New York, New York) |
ABSTRACT | This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. |
FILED | Monday, November 26, 2018 |
APPL NO | 16/200557 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6872 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/117 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/101 (20130101) C12Q 2535/101 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663450 | Tian et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Francisco Bezanilla (Chicago, Illinois); Yuanwen Jiang (Chicago, Illinois); João L. Carvalho-de-Souza (Chicago, Illinois) |
ABSTRACT | Provided herein are Si-based materials, methods of making the Si-based materials, and methods for using the Si-based materials. In embodiments, a silicon-based material comprises an aggregate of particles, the particles comprising an ordered array of nanostructures, the nanostructures comprising amorphous silicon, wherein at least some pairs of adjacent nanostructures are connected by one or more bridges comprising amorphous silicon, the one or more bridges extending from the surface of one nanostructure of the pair to the surface of the other nanostructure in the pair. |
FILED | Wednesday, June 14, 2017 |
APPL NO | 15/623133 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/24 (20130101) C23C 16/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class G01N 33/5014 (20130101) G01N 33/5061 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663750 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, a body (Denver, Colorado) |
INVENTOR(S) | Juin-Yann Yu (Boulder, Colorado); Carol J. Cogswell (Boulder, Colorado); Simeng Chen (Boulder, Colorado); Robert H. Cormack (Erie, Colorado); Jian Xing (Boulder, Colorado) |
ABSTRACT | Apparatus and methods for super-resolution imaging of extended objects utilize a scanned illumination source with a small spot size. Sub-images composed of highly-overlapping point spread functions are captured and each sub-image is iteratively compared to a series of brightness combinations of template point spread functions in a dictionary. The dictionary is composed of highly-overlapping point spread functions. Each sub-image is associated with a best-match template combination solution, and the best-match reconstructions created by best-match solutions are combined into a super-resolution image of the object. |
FILED | Wednesday, March 15, 2017 |
APPL NO | 16/085524 |
ART UNIT | 2484 — Recording and Compression |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/002 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) Original (OR) Class G02B 27/0075 (20130101) Image Data Processing or Generation, in General G06T 3/4053 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664241 | Aly et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Mohamed Ezzat El Hadedy Aly (Champaign, Illinois); Kevin Skadron (Charlottesville, Virginia) |
ABSTRACT | A method operating a memory system, can be provided by reading a plurality of data words from a memory system, where each of the plurality of data words is stored in the memory system in a first dimension-major order. The plurality of data words can be shifted into a transpose memory system in the first dimension in parallel with one another using first directly time adjacent clock edges to store a plurality of transposed data words in a second dimension-major order in the transpose memory system relative to the memory system. The plurality of transposed data words can be shifted out of the transpose memory system in the second dimension using second directly time adjacent clock edges. |
FILED | Friday, October 13, 2017 |
APPL NO | 15/783548 |
ART UNIT | 2137 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 7/785 (20130101) Original (OR) Class G06F 9/30032 (20130101) G06F 12/1009 (20130101) G06F 15/8007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664560 | Pal et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Deepankar Pal (Jeffersonville, Indiana); Nachiket Patil (Louisville, Kentucky); Brent Stucker (Louisville, Kentucky) |
ABSTRACT | Simulation systems, manufacturing systems, software products and controllers are provided with multi-scale modeling in which a coarse mesh and a fine mesh that models a stimulus are decoupled. The fine mesh can be moved within the coarse mesh with a cut and paste operation. The coarse mesh is updated by sparsely propagated effects through the coarse mesh. Simulations of the invention can be conducted in real-time, and be used as controllers in manufacturing systems, such as additive manufacturing systems. A number of efficient methods are provided for solving meshing determinations that arise from movement of a stimulus modeled within a fine mesh. |
FILED | Friday, December 19, 2014 |
APPL NO | 15/105683 |
ART UNIT | 2127 — AI & Simulation/Modeling |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1057 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/12 (20130101) G06F 2217/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664685 | Hoffman et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Zachary R. Hoffman (Boston, Massachusetts); Charles A. DiMarzio (Cambridge, Massachusetts) |
ABSTRACT | Methods, systems, and devices described herein enable single-image optical sectioning, even at depth within turbid media, such as human skin or other tissue. Embodiments can eliminate the need for multiple image samples or raster scans, making in-vivo or live biological imaging easier and faster than multi-image sectioning techniques. Better contrast and resolution than traditional three-phase structured illumination microscopy (SIM) is possible in turbid media. Embodiments enable imaging of cell nuclei. Resolution and contrast resulting from disclosed embodiments are less sensitive to motion of or within patients or other targets than confocal microscopy and three-phase SIM techniques. Three-dimensional images of target specimens can be provided based on a group of single-image optical sections. Real-time imaging can also be provided. |
FILED | Friday, February 02, 2018 |
APPL NO | 15/887966 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/365 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) Original (OR) Class G06K 9/346 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10664978 | Newby et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Jay Mack Newby (Carrboro, North Carolina); M. Gregory Forest (Chapel Hill, North Carolina); Samuel Kit Bunn Lai (Carrboro, North Carolina) |
ABSTRACT | A method for using a synthetically trained neural network for tracking particle movement in video microscopy data includes receiving, as input, video microscopy data representing images of particles that move between video frames. The method includes using a synthetically trained neural network to track movement of the particles between the video frames, wherein the synthetically trained neural network comprises a neural network that is trained on a plurality of different simulated video microscopy data sets. The method further includes outputting, by the synthetically trained neural network, an indication of movement of the particles between the video frames. |
FILED | Tuesday, April 09, 2019 |
APPL NO | 16/379466 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665329 | Eiler et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); Thermo Fisher Scientific (Bremen) GmbH (Bremen, Germany) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THERMO FISHER SCIENTIFIC (BREMEN) GMBH (Bremen, Germany) |
INVENTOR(S) | John M. Eiler (Pasadena, California); Johannes Schwieters (Ganderkesee, Germany) |
ABSTRACT | A mass spectrometer including an entrance slit, an energy filter, a momentum filter and a detector array, the entrance slit, energy filter and momentum filter being configured to provide molecular analyte ions to the detector array at a mass resolution of about 20,000 or greater. A method for determining the isotopic composition of an analyte in a sample includes converting the analyte to molecular analyte ions, separating the molecular analyte ions using an entrance slit, separating the molecular analyte ions according to their energy levels, separating the molecular analyte ions according to their momenta, detecting two or more of the molecular analyte ions at a mass resolution of about 20,000 or greater to produce molecular analyte ion data; and analyzing the molecular analyte data to determine the isotopic composition of at least a portion of the analyte. |
FILED | Wednesday, June 07, 2017 |
APPL NO | 15/616533 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665634 | Zhao et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Qingyuan Zhao (Malden, Massachusetts); Karl K. Berggren (Arlington, Massachusetts) |
ABSTRACT | An integrated, superconducting imaging sensor may be formed from a single, meandering nanowire. The sensor is capable of single-photon (or single-event) detection and imaging with ˜10 micron spatial resolution and sub-100-picosecond temporal resolution. The sensor may be readily scaled to large areas. |
FILED | Thursday, February 02, 2017 |
APPL NO | 15/423446 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/44 (20130101) G01J 3/0286 (20130101) G01J 3/2803 (20130101) G01J 5/20 (20130101) G01J 5/023 (20130101) G01J 5/061 (20130101) G01J 2001/442 (20130101) G01J 2001/4446 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 27/18 (20130101) Original (OR) Class H01L 39/10 (20130101) H01L 39/16 (20130101) H01L 39/125 (20130101) H01L 39/2416 (20130101) H01L 2223/6627 (20130101) H01L 2223/6672 (20130101) Pictorial Communication, e.g Television H04N 5/378 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665896 | Long et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jeffrey R. Long (Oakland, California); Jeffrey F. Van Humbeck (Watertown, Massachusetts); Jordan C. Axelson (Berkeley, California) |
ABSTRACT | The disclosure provides for polymer networks having the general structure: that can effectively serve as a single-ion conducting electrolyte. |
FILED | Friday, June 10, 2016 |
APPL NO | 15/580655 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/13 (20170101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/00 (20130101) C08G 65/337 (20130101) C08G 65/338 (20130101) C08G 75/14 (20130101) C08G 79/08 (20130101) C08G 81/00 (20130101) C08G 83/00 (20130101) Compositions of Macromolecular Compounds C08L 71/00 (20130101) C08L 85/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666091 | Joannopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. A third high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. The source resonator and at least one of the second resonator and third resonator may be coupled to transfer electromagnetic energy from said source resonator to said at least one of the second resonator and third resonator. |
FILED | Thursday, November 08, 2018 |
APPL NO | 16/184354 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/50 (20190201) B60L 53/12 (20190201) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) Antennas, i.e Radio Aerials H01Q 9/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 10/7005 (20130101) Y02T 10/7072 (20130101) Y02T 10/7088 (20130101) Y02T 90/14 (20130101) Y02T 90/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/25 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666504 | Bhatia et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Udit Bhatia (Boston, Massachusetts); Devashish Kumar (Boston, Massachusetts); Evan Kodra (Cambridge, Massachusetts); Auroop R. Ganguly (Medford, Massachusetts) |
ABSTRACT | A method and system for providing a recovery sequence for a network from a state of disruption to a state of partial or complete functionality are provided. The method and system can measure the response of a network to one or multiple hazards and can generate and compare the effectiveness of multiple recovery strategies in a quantitative and generalizable manner, providing a user with practical tools to implement an efficient restoration of the network. |
FILED | Friday, June 07, 2019 |
APPL NO | 16/434443 |
ART UNIT | 2414 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0672 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
10663350 — Two-dimensional phononic metamaterial filter structure for ultra-low-background detectors
US 10663350 | Wollack et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administration of NASA (Washington, District of Columbia) |
INVENTOR(S) | Edward J. Wollack (Clarksville, Maryland); David T. Chuss (Beryn, Pennsylvania); Kevin L. Denis (Crofton, Maryland); Samuel H. Moseley (University Park, Maryland); Karwan Rostem (Glenarden, Maryland) |
ABSTRACT | A phononic filter includes a metamaterial body including a membrane including a crystalline or amorphous dielectric material, an elemental superconductor or an alloyed superconductor; and a plurality of spaced features. The spaced features includes holes, spacings, or apertures in the metamaterial body. |
FILED | Friday, June 22, 2018 |
APPL NO | 16/015450 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/06 (20130101) Original (OR) Class G01J 5/20 (20130101) G01J 5/0205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10663376 | Agui et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Juan H. Agui (Strongsville, Ohio); Rajagopal Vijayakumar (Liverpool, New York) |
ABSTRACT | An apparatus includes a motor having a first shaft extending therefrom. The motor is configured to apply energy to the first shaft. A particle cartridge mechanically is coupled to the motor via the first shaft. The particle cartridge includes a screen separating an internal volume of the particle cartridge from an environment of the apparatus, and a plurality of particles disposed within the internal volume. A particle manipulation element is mechanically coupled to the first shaft and in contact with the plurality of particles. The particle manipulation element moves in response to the energy being applied to the first shaft to force some of the particles through the screen and into the environment of the apparatus. |
FILED | Monday, September 17, 2018 |
APPL NO | 16/133141 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Separation B01D 45/08 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 12/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2208 (20130101) Original (OR) Class G01N 2001/2223 (20130101) G01N 2015/0261 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665115 | Fragoso et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Anthony T. S. Fragoso (Los Angeles, California); Larry H. Matthies (Northridge, California); Roland Brockers (Pasadena, California); Richard M. Murray (Pasadena, California) |
ABSTRACT | A method, device, framework, and system provide the ability to control an unmanned aerial vehicle (UAV) to avoid obstacle collision. Range data of a real-world scene is acquired using range sensors (that provide depth data to visible objects). The range data is combined into an egospace representation (consisting of pixels in egospace). An apparent size of each of the visible objects is expanded based on a dimension of the UAV. An assigned destination in the real world scene based on world space is received and transformed into egospace coordinates in egospace. A trackable path from the UAV to the assigned destination through egospace that avoids collision with the visible objects (based on the expanded apparent sizes of each of the visible objects) is generated. Inputs that control the UAV to follow the trackable path are identified. |
FILED | Thursday, December 29, 2016 |
APPL NO | 15/394647 |
ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/126 (20130101) B64C 2201/127 (20130101) B64C 2201/141 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/005 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/86 (20200101) G01S 17/89 (20130101) G01S 17/933 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/102 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/00624 (20130101) G06K 9/6202 (20130101) Traffic Control Systems G08G 5/045 (20130101) G08G 5/0069 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10665310 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Yue Li (Pasadena, California); Jehoshua Bruck (La Cañada Flintridge, California) |
ABSTRACT | A radiation hardened NAND flash memory data storage device suitable for space flight having a plurality of memory cells configured to store data values in accordance with a predetermined rank modulation scheme and a memory controller that receives a current error count from an error decoder of the data device for one or more data operations of the flash memory device and selects an operating mode for data scrubbing in accordance with the received error count and a program cycles count. Methods of operating the data storage device are also described. |
FILED | Monday, January 28, 2019 |
APPL NO | 16/259143 |
ART UNIT | 2825 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 16/10 (20130101) G11C 16/16 (20130101) G11C 16/0466 (20130101) G11C 16/3495 (20130101) Original (OR) Class G11C 29/44 (20130101) G11C 2029/0409 (20130101) G11C 2211/5641 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10667398 | Petrick et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | David J. Petrick (Severna Park, Maryland); Alessandro D. Geist (Bethesda, Maryland); Thomas P. Flatley (Huntington, Maryland) |
ABSTRACT | The present invention relates to a single board computer system with an improved memory and layout. The unique layout of the printed circuit board of the present invention allows for different parts to be placed in a back-to-back configuration to minimize the dimensions of the printed circuit board. This includes a high-performance radiation-hardened reconfigurable FPGA, for processing computation-intensive space systems, disposed on both sides of the printed circuit board. Four dual double data rate synchronous dynamic random-access memories (DDR2 SDRAMs) disposed on both the top side and on the bottom side of the printed circuit board reduce an operating voltage of said printed circuit board. A layout stack-up of the printed circuit board includes twenty-two symmetrical layers including ten ground layers, four power layers, six signal layers, a top layer, and a bottom layer. |
FILED | Wednesday, September 26, 2018 |
APPL NO | 16/142183 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/0727 (20130101) G06F 11/0793 (20130101) Pulse Technique H03K 19/0033 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/115 (20130101) H05K 1/181 (20130101) Original (OR) Class H05K 1/0203 (20130101) H05K 1/0298 (20130101) H05K 2201/093 (20130101) H05K 2201/09327 (20130101) H05K 2201/09509 (20130101) H05K 2201/10159 (20130101) H05K 2201/10212 (20130101) H05K 2201/10522 (20130101) H05K 2201/10545 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 10662384 | Rovani, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
ASSIGNEE(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
INVENTOR(S) | Joseph F. Rovani, Jr. (Laramie, Wyoming); Jeramie Joseph Adams (Laramie, Wyoming); Ryan Bradley Boysen (Laramie, Wyoming); Jean-Pascal Planche (Laramie, Wyoming); Nicholas David Bolton (Laramie, Wyoming) |
ABSTRACT | The present invention is generally related to the analysis of chemical compositions of hydrocarbons and hydrocarbon blends. This method applies specifically to the problem of analyzing extremely complex hydrocarbon-containing mixtures when the number and diversity of molecules makes it impossible to realistically identify and quantify them individually in a reasonable timeframe and cost. The advantage to this method over prior art is the ability to separate and identify chemical constituents and solvent fractions based on their solvent-solubility characteristics, their high performance liquid chromatographic (HPLC) adsorption and desorption behaviors, and their interactions with stationary phases; and subsequently identify and quantify them at least partially using various combinations of non-destructive HPLC, destructive HPLC, and stand-alone detectors presently not routinely used for HPLC but reconfigured to obtain spectra on the fly. This analytical method is especially useful for, but not limited to, asphalt binders and asphalt binder blends, modified asphalts, asphalt modifiers, asphalt additives, polymer-modified asphalts, asphalts containing rejuvenators and softening agents, asphalts containing recycled products, aged asphalts, and air-blown asphalts, which may contain wide varieties of different types of additives and chemistries, and forensic applications, and environmental pollutant identification. |
FILED | Wednesday, November 07, 2018 |
APPL NO | 16/183649 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 15/00 (20130101) B01D 15/265 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/281 (20130101) B01J 20/283 (20130101) B01J 20/284 (20130101) B01J 20/286 (20130101) B01J 20/287 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/003 (20130101) Original (OR) Class C10G 25/12 (20130101) C10G 53/08 (20130101) C10G 2400/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/14 (20130101) G01N 30/461 (20130101) G01N 30/468 (20130101) G01N 33/2823 (20130101) G01N 33/2835 (20130101) G01N 2030/027 (20130101) G01N 2030/085 (20130101) G01N 2030/143 (20130101) G01N 2030/8854 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10662535 | Alnaser et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Tulsa (Tulsa, Oklahoma) |
ASSIGNEE(S) | The University of Tulsa (Tulsa, Oklahoma) |
INVENTOR(S) | Ibrahim A. Alnaser (Tulsa, Oklahoma); Michael Keller (Tulsa, Oklahoma) |
ABSTRACT | A process to detect damage to a bonded composite repair of metal equipment. The process includes the steps of monitoring electrical resistance in a direct current impressed current cathodic protection circuit having a power supply and an anode in electrical communication with metal equipment having a bonded composite repair thereto. Deterioration of the bonded composite repair is detected based on a change in the electrical resistance of the circuit. |
FILED | Friday, July 13, 2018 |
APPL NO | 16/034826 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/22 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 31/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 10663446 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | FREMONTA Corporation (Fremont, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
ASSIGNEE(S) | FREMONTA Corporation (Fremont, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
INVENTOR(S) | Florence Wu (Milpitas, California); Yongqing Huang (Newark, California); Terrance Arthur (Hastings, Nebraska); Tommy Wheeler (Clay Center, Nebraska) |
ABSTRACT | Systems and methods for sampling within a conveyance system are provided herein, such systems and methods being particularly useful in batch sampling of food products for a targeted biological agent. In one aspect, the sampling system includes a conveyance system and one or more sampling devices positioned along a conveyance path such that at least one portion of the batch contacts a sampling medium of the one or more sampling devices. In another aspect, sampling devices are provided that allow a sampling member to be secured in a sampling position for batch testing and readily removed after sampling and tested. The systems, devices and methods herein provide improved sampling coverage of the entire batch and reduce waste and inefficiency as compared to conventional batch sampling methods. |
FILED | Wednesday, February 18, 2015 |
APPL NO | 14/625308 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 1/04 (20130101) G01N 1/20 (20130101) G01N 33/12 (20130101) Original (OR) Class G01N 35/02 (20130101) G01N 2001/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 10660553 | Abee |
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FUNDED BY |
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APPLICANT(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | U.S. Department of Veteran Affairs (Washington, District of Columbia) |
INVENTOR(S) | Catherine P. Abee (McKees Rocks, Pennsylvania) |
ABSTRACT | Method and apparatus for providing reliable blood oxygen (SaO2) and heart rate measurements includes a chemical energy heating source in conjunction with a harness that is adapted to secure the chemical energy heating source and a pulse oximeter probe proximate to a region of the body which is to be warmed prior to measurement. Preferably, the chemical energy heating source is in the form a mixture including a metal powder, which releases heat at a predetermined rate via oxidation of the metal powder when exposed to the atmosphere. The apparatus may be designed to be reusable or disposable and can be used in a transmission or reflectance mode, or both. |
FILED | Thursday, September 07, 2017 |
APPL NO | 15/698370 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1491 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/14551 (20130101) A61B 5/14552 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
European Union (EU)
US 10663601 | Curran et al. |
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FUNDED BY |
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APPLICANT(S) | The European Union, represented by the European Commission (Brussels, Belgium) |
ASSIGNEE(S) | THE EUROPEAN UNION (Brussels, Belgium) |
INVENTOR(S) | James T Curran (Ispra, Italy); Michele Bavaro (Sesto Calende, Italy); Joaquim Fortuny-Guasch (Taino, Italy) |
ABSTRACT | The invention provides an atmospheric monitoring and measurement system based on the processing of global navigation satellite system radio-frequency signals. The invention is characterized by an open-loop demodulation architecture to extract amplitude and phase information from the received satellite signals, and a signal processing technique which can provide statistics relating to the amplitude and phase variations induced by the atmosphere. |
FILED | Friday, March 27, 2015 |
APPL NO | 15/300028 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/00 (20130101) G01S 19/24 (20130101) G01S 19/40 (20130101) Original (OR) Class G01S 19/072 (20190801) G01S 19/243 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 10664241 | Aly et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Mohamed Ezzat El Hadedy Aly (Champaign, Illinois); Kevin Skadron (Charlottesville, Virginia) |
ABSTRACT | A method operating a memory system, can be provided by reading a plurality of data words from a memory system, where each of the plurality of data words is stored in the memory system in a first dimension-major order. The plurality of data words can be shifted into a transpose memory system in the first dimension in parallel with one another using first directly time adjacent clock edges to store a plurality of transposed data words in a second dimension-major order in the transpose memory system relative to the memory system. The plurality of transposed data words can be shifted out of the transpose memory system in the second dimension using second directly time adjacent clock edges. |
FILED | Friday, October 13, 2017 |
APPL NO | 15/783548 |
ART UNIT | 2137 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 7/785 (20130101) Original (OR) Class G06F 9/30032 (20130101) G06F 12/1009 (20130101) G06F 15/8007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 10663500 | Hoff |
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FUNDED BY |
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APPLICANT(S) | Clean Power Research, L.L.C. (Napa, California) |
ASSIGNEE(S) | CLEAN POWER RESEARCH, L.L.C. (Napa, California) |
INVENTOR(S) | Thomas E. Hoff (Napa, California) |
ABSTRACT | The accuracy of photovoltaic simulation modeling is predicated upon the selection of a type of solar resource data appropriate to the form of simulation desired. Photovoltaic power simulation requires irradiance data. Photovoltaic energy simulation requires normalized irradiation data. Normalized irradiation is not always available, such as in photovoltaic plant installations where only point measurements of irradiance are sporadically collected or even entirely absent. Normalized irradiation can be estimated through several methodologies, including assuming that normalized irradiation simply equals irradiance, directly estimating normalized irradiation, applying linear interpolation to irradiance, applying linear interpolation to clearness index values, and empirically deriving irradiance weights. The normalized irradiation can then be used to forecast photovoltaic fleet energy production. |
FILED | Monday, June 03, 2019 |
APPL NO | 16/429534 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 21/1331 (20130101) Original (OR) Class Meteorology G01W 1/02 (20130101) G01W 1/12 (20130101) Electric Digital Data Processing G06F 17/11 (20130101) G06F 17/16 (20130101) G06F 30/20 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/04 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) H02J 2203/20 (20200101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/00 (20130101) H02S 50/15 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101) Y02E 60/76 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/30 (20151101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 10664749 | Pilly et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Praveen K. Pilly (West Hills, California); Michael D. Howard (Westlake Village, California); Rajan Bhattacharyya (Sherman Oaks, California) |
ABSTRACT | Described is a system for storing and retrieving a memory in context. A memory formed for a given context is encoded in a neural model of the entorhinal-hippocampal system, forming a context-appropriate memory. The context-appropriate memory is comprised of an association between presented environmental cues and presence of a rewarded event. The system is able to discriminate between environmental cues in an environment surrounding a vehicle and retrieve at least one encoded context-appropriate memory. Using the at least one retrieved encoded context-appropriate memory, the system determines whether to initiate a collision avoidance operation to cause the vehicle to proactively avoid a collision. |
FILED | Thursday, April 07, 2016 |
APPL NO | 15/093730 |
ART UNIT | 2125 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10666248 | Cosand |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Albert E. Cosand (Agoura Hills, California) |
ABSTRACT | A circuit biases an input transistor by using a voltage on a reference transistor having open gate connection and operating at the same current density as the input transistor to null current leakage at the gate of the input transistor. The input transistor is biased based on the voltage on the zero-gate-current reference transistor. The bias condition for the input transistor to operate at a zero gate current is determined by leaving the gate terminal of the reference transistor open-circuited, thus zero gate current, forcing a desired current through the reference transistor, and measuring a drain-source voltage of the reference transistor. When the input terminal of the input transistor has an ancillary circuitry that may contribute gate leakage current, the same ancillary circuitry can be coupled to the gate of the reference transistor. |
FILED | Thursday, April 18, 2019 |
APPL NO | 16/387532 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Amplifiers H03F 3/45071 (20130101) H03F 2200/129 (20130101) H03F 2200/156 (20130101) H03F 2200/471 (20130101) H03F 2203/45116 (20130101) H03F 2203/45534 (20130101) Pulse Technique H03K 17/165 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 26, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200526.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page