FedInvent™ Patents

Patent Details for Tuesday, June 16, 2020 

This page was updated on Monday, March 27, 2023 at 06:06 AM GMT

Department of Health and Human Services (HHS) 

US 10682108 Ma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
INVENTOR(S) Ruibin Ma (Durham, North Carolina);  Rui Wang (Chapel Hill, North Carolina);  Stephen Murray Pizer (Chapel Hill, North Carolina);  Jan-Michael Frahm (Chapel Hill, North Carolina);  Julian Gary Rosenman (Chapel Hill, North Carolina);  Sarah Kelly McGill (Chapel Hill, North Carolina)
ABSTRACT Methods, systems, and computer readable media for deriving a three-dimensional (3D) surface from colonoscopic video are disclosed. According to one method for deriving a 3D surface from colonoscopic video, the method comprises: performing video frame preprocessing to identify a plurality of keyframes of a colonoscopic video, wherein the video frame preprocessing includes informative frame selection and keyframe selection; generating, using a recurrent neural network and direct sparse odometry, camera poses and depth maps for the keyframes; and fusing, using SurfelMeshing and the camera poses, the depth maps into a three-dimensional (3D) surface of a colon portion, wherein the 3D surface indicates at least one region of the colon portion that was not visualized.
FILED Tuesday, July 16, 2019
APPL NO 16/513632
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/31 (20130101)
A61B 6/466 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/20 (20130101)
G06T 7/136 (20170101)
G06T 15/205 (20130101)
G06T 2207/30032 (20130101)
G06T 2219/2004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682147 Grant et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of America, as represented by the Secretary of Defense (Washington, District of Columbia)
INVENTOR(S) Gerald Grant (Goshen, Kentucky);  Peter Liacouras (North Potomac, Maryland);  Chad Gordon (Lutherville, Maryland);  Ryan Murphy (Columbia, Maryland);  Mehran Armand (Fulton, Maryland)
ABSTRACT A surgical guide assembly having an attachment device configured to be coupled to a bone. A cut location indicator is coupled to the attachment device. The cut location indicator identifies a location where the bone is to be cut. An arm is coupled to the attachment device, the cut location indicator, or both. A support structure is coupled to the arm. The support structure is configured to have a trackable feature coupled thereto.
FILED Monday, November 24, 2014
APPL NO 15/100252
ART UNIT 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/15 (20130101) Original (OR) Class
A61B 17/176 (20130101)
A61B 17/1695 (20130101)
A61B 17/1739 (20130101)
A61B 17/8085 (20130101)
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 2034/105 (20160201)
A61B 2034/108 (20160201)
A61B 2034/2051 (20160201)
A61B 2034/2055 (20160201)
A61B 2034/2065 (20160201)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2803 (20130101)

Electric Digital Data Processing
G06F 19/3481 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/50 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/26 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682260 Laulicht et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Bryan Laulicht (Cambridge, Massachusetts);  Jeffrey M. Karp (Brookline, Massachusetts);  Robert S. Langer (Newton, Massachusetts)
ABSTRACT Methods and compositions for securing to and removing adhesive tapes from substrates, e.g., delicate substrates such as skin, are described. The methods include providing an adhesive tape comprising an adhesive layer and a support layer in contact with the adhesive layer. A first adhesion level between the adhesive layer and the support layer is, or can be controlled to be, less than a second adhesion level between the adhesive layer and the substrate. The methods further include applying the adhesive tape to the substrate by contacting the adhesive layer to the substrate while the support layer remains in contact with the adhesive layer; and removing the support layer from the substrate by separating the support layer from the adhesive layer.
FILED Monday, March 05, 2018
APPL NO 15/911370
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/024 (20130101) Original (OR) Class
A61F 13/025 (20130101)
A61F 13/0246 (20130101)
A61F 13/0253 (20130101)
A61F 13/0256 (20130101)
A61F 13/0259 (20130101)
A61F 13/0269 (20130101)
A61F 2013/008 (20130101)
A61F 2013/0071 (20130101)
A61F 2013/00412 (20130101)
A61F 2013/00676 (20130101)
A61F 2013/00685 (20130101)
A61F 2013/00702 (20130101)
A61F 2013/00748 (20130101)
A61F 2013/00804 (20130101)
A61F 2013/00838 (20130101)
A61F 2013/15569 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/5021 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 37/26 (20130101)
B32B 38/10 (20130101)
B32B 2037/268 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 7/255 (20180101)
C09J 2205/302 (20130101)
C09J 2467/006 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2839 (20150115)
Y10T 428/24851 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682309 Elbert et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Donald L. Elbert (Austin, Texas);  Jacob Roam (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Donald L. Elbert (Austin, Texas);  Jacob Roam (St. Louis, Missouri)
ABSTRACT Disclosed herein is a device and method for regenerating tissue using a modular scaffold having a gradient of enzymatic degradability. The disclosure further relates to scaffolds made of microparticles comprising a cross-linked water-soluble polymer or cross-linked water-soluble polymers and a process for forming thereof.
FILED Tuesday, October 16, 2018
APPL NO 16/161809
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101) Original (OR) Class
A61K 47/36 (20130101)
A61K 47/65 (20170801)
A61K 47/6903 (20170801)
A61K 47/6933 (20170801)
A61K 47/6935 (20170801)

Peptides
C07K 14/78 (20130101)
C07K 14/475 (20130101)
C07K 14/4756 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/0075 (20130101)
C08B 37/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682320 Barnett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) West Virginia University (Morgantown, West Virginia);  University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Temple University-Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) West Virginia University (Morgantown, West Virginia);  Temple University-Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania);  University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) John B. Barnett (Morgantown, West Virginia);  Harry C. Blair (Pittsburgh, Pennsylvania);  Jonathan Soboloff (Cheltenham, Pennsylvania)
ABSTRACT This invention provides a composition comprising Formula I, or salt thereof,
wherein X is either chlorine or bromine, Y is either hydrogen or an alkyl group having a carbon chain length from 1 to 5 carbon atoms, and R is an alkyl group having a carbon chain length from 1 to 5 carbon atoms, except that X is not chlorine when Y is hydrogen and R is an ethyl group. A method of preventing bone erosion in a patient and a method of reducing inflammation in a patient using the compositions of Formula I are disclosed.
FILED Wednesday, April 17, 2013
APPL NO 13/864438
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/167 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682339 Cox et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute on Minority Health and Health Disparities (NIMHD)
APPLICANT(S) Marc Cox (El Paso, Texas);  Artem Cherkasov (El Paso, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas);  THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada)
INVENTOR(S) Marc Cox (El Paso, Texas);  Artem Cherkasov (El Paso, Texas)
ABSTRACT Embodiments of the current invention include methods and compositions for regulating the activity of hormone receptors.
FILED Friday, May 17, 2019
APPL NO 16/415141
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4184 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 235/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682341 Prossnitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Eric R. Prossnitz (Albuquerque, New Mexico);  Matthias Barton (Zurich, Switzerland);  Matthias R. Meyer (Stallikon, Switzerland)
ABSTRACT The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).
FILED Wednesday, January 30, 2019
APPL NO 16/262461
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/16 (20130101)
A61K 31/435 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 31/437 (20130101)
A61K 31/4355 (20130101)
A61K 31/7088 (20130101)
A61K 38/28 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682347 Govindan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Immunomedics, Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Immunomedics, Inc. (Morris Plains, New Jersey)
INVENTOR(S) Serengulam V. Govindan (Summit, New Jersey);  David M. Goldenberg (Mendham, New Jersey)
ABSTRACT The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy.
FILED Friday, September 28, 2018
APPL NO 16/145755
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/481 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/454 (20130101)
A61K 31/513 (20130101)
A61K 31/675 (20130101)
A61K 31/713 (20130101)
A61K 31/4184 (20130101)
A61K 31/4375 (20130101)
A61K 31/4745 (20130101) Original (OR) Class
A61K 31/7088 (20130101)
A61K 45/06 (20130101)
A61K 47/6803 (20170801)
A61K 47/6851 (20170801)
A61K 47/6853 (20170801)
A61K 2039/55 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/32 (20130101)
C07K 16/303 (20130101)
C07K 16/2803 (20130101)
C07K 16/2833 (20130101)
C07K 16/2887 (20130101)
C07K 16/3007 (20130101)
C07K 16/3015 (20130101)
C07K 16/3023 (20130101)
C07K 16/3061 (20130101)
C07K 16/3092 (20130101)
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682349 Bassaganya-Riera et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Landos Biopharma, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) LANDOS BIOPHARMA, INC. (Blacksburg, Virginia)
INVENTOR(S) Josep Bassaganya-Riera (Blacksburg, Virginia);  Adria Carbo Barrios (Blacksburg, Virginia);  Richard Gandour (Blacksburg, Virginia);  Julian D. Cooper (Blacksburg, Virginia);  Raquel Hontecillas (Blacksburg, Virginia)
ABSTRACT Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including infectious disease, autoimmune disease, diabetes, and a chronic inflammatory disease.
FILED Tuesday, October 15, 2019
APPL NO 16/653446
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/423 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)

Acyclic or Carbocyclic Compounds
C07C 65/40 (20130101)

Heterocyclic Compounds
C07D 213/69 (20130101)
C07D 213/79 (20130101)
C07D 307/60 (20130101)
C07D 307/68 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 403/14 (20130101)
C07D 413/12 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682367 Fuchs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
NIH Office of the Director (NIHOD)
APPLICANT(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S) James Fuchs (Columbus, Ohio);  Alan Douglas Kinghorn (Columbus, Ohio);  Andrew Huntsman (Fort Jennings, Ohio)
ABSTRACT Described are arylnaphthalene lactone derivatives. Also disclosed herein are methods of use of the arylnaphthalene lactone derivatives as anticancer agents.
FILED Wednesday, April 26, 2017
APPL NO 16/079754
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/365 (20130101)
A61K 31/7048 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2121/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 17/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682374 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Intstitute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yizhou Dong (Dublin, Ohio);  Kevin Thomas Love (Boston, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Daniel Griffith Anderson (Framingham, Massachusetts);  Delai Chen (Cambridge, Massachusetts);  Yi Chen (Cambridge, Massachusetts);  Arturo Jose Vegas (Belmont, Massachusetts);  Akinleye C. Alabi (Ithaca, New York);  Yunlong Zhang (Cambridge, Massachusetts)
ABSTRACT Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein:
wherein m, n, p, R′, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.
FILED Monday, September 10, 2018
APPL NO 16/126897
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)
A61K 31/7105 (20130101) Original (OR) Class
A61K 47/22 (20130101)
A61K 2121/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 229/12 (20130101)
C07C 229/22 (20130101)
C07C 229/24 (20130101)
C07C 229/26 (20130101)
C07C 229/36 (20130101)
C07C 237/08 (20130101)
C07C 237/12 (20130101)
C07C 271/22 (20130101)
C07C 279/14 (20130101)
C07C 323/58 (20130101)

Heterocyclic Compounds
C07D 207/16 (20130101)
C07D 209/20 (20130101)
C07D 209/24 (20130101)
C07D 233/64 (20130101)
C07D 241/08 (20130101)
C07D 265/32 (20130101)
C07D 403/06 (20130101)
C07D 413/06 (20130101)
C07D 487/04 (20130101)
C07D 487/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/88 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/15 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/463 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682378 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Tong Zhang (Lebanon, New Hampshire);  Charles L. Sentman (Grantham, New Hampshire)
ABSTRACT The invention is directed to T cells and other cells that express chimeric NK-p30 receptors (“chimeric NKp30 T cells”), methods of making and using chimeric NKp30 T cells, and methods of using these chimeric NKp30 T cells, isolated populations thereof, and compositions comprising the same. In another aspect, said chimeric NKp30 T cells are further designed to express a functional non-TCR receptor. The disclosure also pertains to methods of making said chimeric NKp30 T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said chimeric NKp30 T cells, populations thereof, or compositions comprising the same.
FILED Monday, December 04, 2017
APPL NO 15/830605
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 38/00 (20130101)

Peptides
C07K 14/70503 (20130101)
C07K 14/70521 (20130101)
C07K 14/70575 (20130101)
C07K 14/70578 (20130101)
C07K 14/70596 (20130101)
C07K 2319/00 (20130101)
C07K 2319/03 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 2800/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682379 Myles et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S) Ian Antheni Myles (Bethesda, Maryland);  Sandip K. Datta (Bethesda, Maryland)
ABSTRACT Pharmaceutical compositions are disclosed that includes a therapeutically effective amount of a purified viable gram negative bacteria and a pharmaceutically acceptable carrier. The pharmaceutical compositions are formulated for topical administration. Methods of treating atopic dermatitis using these pharmaceutical compositions are also disclosed.
FILED Wednesday, January 16, 2019
APPL NO 16/249721
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0014 (20130101)
A61K 35/74 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 17/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682392 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  ACCELERON PHARMA, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE BRINGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  ACCELERON PHARMA, INC. (Cambridge, Massachusetts)
INVENTOR(S) Paul Yu (Boston, Massachusetts);  Asya Grinberg (Lexington, Massachusetts);  Dianne S. Sako (Medford, Massachusetts);  Roselyne Castonguay (Malden, Massachusetts);  Rita Steeves (Stoneham, Massachusetts);  Ravindra Kumar (Acton, Massachusetts)
ABSTRACT In some aspects, the invention teaches pharmaceutical compositions that include a TGF-beta ligand trap, and methods of using a TGF-beta ligand trap to treat, prevent, or reduce the progression rate of pulmonary hypertension (PH). The invention also provides methods of using a TGF-beta ligand trap to treat, prevent, or reduce the progression rate of a variety of conditions including, but not limited to, pulmonary vascular remodeling, pulmonary fibrosis, right ventricular hypertrophy, diseases associated with excessive TGF-beta signaling, diseases associated with excessive GDF15 signaling, and diseases associated with excessive PAI-1 signaling. The invention further provides methods of using a TGF-beta ligand trap to reduce right ventricular systolic pressure in a subject.
FILED Friday, November 21, 2014
APPL NO 15/037852
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/179 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/12 (20180101)

Peptides
C07K 14/71 (20130101)
C07K 19/00 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682393 Srinivasan
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Emory University (Atlanta, Georgia);  U.S. Government represented by the United States Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  The United States Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Shanthi Srinivasan (Atlanta, Georgia)
ABSTRACT The disclosure relates to therapeutic methods for regulating weight gain, metabolic syndrome, and insulin resistance. In certain embodiments, the disclosure relates to methods of treating or preventing obesity, metabolic syndrome, or insulin resistance by administering an effective amount of a pharmaceutical composition comprising one or more GDNF receptor agonists to a subject in need thereof.
FILED Tuesday, July 17, 2018
APPL NO 16/037268
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/185 (20130101) Original (OR) Class

Peptides
C07K 14/475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682397 Auerbach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Duke University (Durham, North Carolina)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Duke University (Durham, North Carolina)
INVENTOR(S) Benjamin David Auerbach (Buffalo, New York);  Mark Firman Bear (Boston, Massachusetts);  Laura Jane Stoppel (Cambridge, Massachusetts);  Robert J. Lefkowitz (Durham, North Carolina)
ABSTRACT Disclosed herein are novel methodologies of treating fragile X syndrome and related disorders by inhibiting mGlu5-relevant signaling pathways via the reduction of β-arrestin2 protein levels or the diminution of mGlu5 and β-arrestin2 protein interactions.
FILED Wednesday, November 30, 2016
APPL NO 15/364332
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2217/15 (20130101)
A01K 2217/075 (20130101)
A01K 2217/077 (20130101)
A01K 2227/105 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101) Original (OR) Class
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/115 (20130101)
C12N 15/1138 (20130101)
C12N 2310/10 (20130101)
C12N 2310/11 (20130101)
C12N 2310/12 (20130101)
C12N 2310/14 (20130101)
C12N 2310/16 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3231 (20130101)
C12N 2310/3233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682399 Hunt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia);  The University of Birmingham (Birmingham, United Kingdom)
ASSIGNEE(S) The University of Birmingham (Birmingham, United Kingdom);  University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Donald F. Hunt (Charlottesville, Virginia);  Jeffrey Shabanowitz (Charlottesville, Virginia);  Jennifer G. Abelin (Sommers, Connecticut);  Mark Cobbold (Birmingham, United Kingdom);  Sarah Amy Penny (Birmingham, United Kingdom)
ABSTRACT A set of target peptides are presented by HLA A*0201, B*0301, B*0702 and B*2705 on the surface of disease cells. They are envisioned to, among other things, stimulate an immune response to the proliferative disease, e.g., colorectal cancer, to function as immunotherapeutics in adoptive T cell therapy or as a vaccine, facilitate antibody recognition of tumor boundaries in surgical pathology samples, act as biomarkers for early detection and/or diagnosis of the disease, and/or act as targets in the generation antibody-like molecules which recognize the target-peptide/MHC complex.
FILED Thursday, September 05, 2013
APPL NO 14/425946
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101) Original (OR) Class
A61K 2039/555 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57419 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682400 Ali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Omar Abdel-Rahman Ali (Cambridge, Massachusetts);  David J. Mooney (Sudbury, Massachusetts);  Glenn Dranoff (Lexington, Massachusetts)
ABSTRACT The present invention comprises compositions, methods, and devices for enhancing an endogenous immune response against a cancer. Devices and methods provide therapeutic immunity to subjects against cancer.
FILED Thursday, April 30, 2015
APPL NO 15/303985
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/3955 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101)
A61K 2039/54 (20130101)
A61K 2039/507 (20130101)
A61K 2039/5152 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55522 (20130101)
A61K 2039/55561 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/2803 (20130101)
C07K 16/2818 (20130101)
C07K 16/3053 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682410 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Lexington, Massachusetts);  John Anthony Zuris (Cambridge, Massachusetts);  David B. Thompson (Cambridge, Massachusetts)
ABSTRACT Compositions, methods, strategies, kits, and systems for the supercharged protein-mediated delivery of functional effector proteins into cells in vivo, ex vivo, or in vitro are provided. Compositions, methods, strategies, kits, and systems for delivery of functional effector proteins using cationic lipids and cationic polymers are also provided. Functional effector proteins include, without limitation, transcriptional modulators (e.g., repressors or activators), recombinases, nucleases (e.g., RNA-programmable nucleases, such as Cas9 proteins; TALE nuclease, and zinc finger nucleases), deaminases, and other gene modifying/editing enzymes. Functional effector proteins include TALE effector proteins, e.g., TALE transcriptional activators and repressors, as well as TALE nucleases. Compositions, methods, strategies, and systems for the delivery of functional effector proteins into cells is useful for therapeutic and research purposes, including, but not limited to, the targeted manipulation of a gene associated with disease, the modulation of the expression level of a gene associated with disease, and the programming of cell fate.
FILED Friday, September 05, 2014
APPL NO 14/916679
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 38/45 (20130101)
A61K 38/465 (20130101)
A61K 38/1767 (20130101)
A61K 47/12 (20130101) Original (OR) Class

Peptides
C07K 14/00 (20130101)
C07K 14/195 (20130101)
C07K 14/463 (20130101)
C07K 14/4702 (20130101)
C07K 14/43595 (20130101)
C07K 2319/60 (20130101)
C07K 2319/80 (20130101)
C07K 2319/85 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/22 (20130101)
C12N 9/96 (20130101)
C12N 9/1241 (20130101)

Enzymes
C12Y 207/07 (20130101)
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682411 Monson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
ASSIGNEE(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
INVENTOR(S) Ellen K. Monson (Cincinnati, Ohio);  Xiaochen Wei (Fort Mitchell, Kentucky);  Ray Takigiku (Covington, Kentucky);  Charles A. Cruze, III (West Chester, Ohio);  Joseph W. Wyse (Nicholasville, Kentucky)
ABSTRACT Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers.
FILED Friday, November 02, 2018
APPL NO 16/179139
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/127 (20130101)
A61K 38/18 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101) Original (OR) Class
A61K 47/18 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682413 Yang
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Fedora Pharmaceuticals Inc. (Edmonton, Canada);  Meiji Seika Pharma Co., Ltd. (Tokyo, Japan)
ASSIGNEE(S) FEDORA PHARMACEUTICALS INC. (Edmonton, Alberta, Canada);  MEIJI SEIKA PHARMA CO., LTD. (Tokyo, Japan)
INVENTOR(S) Kewei Yang (Basel, Switzerland)
ABSTRACT The present invention relates to a pharmaceutical composition and a lyophilisate of a diazabicyclooctane derivative represented by Compound I, a process for producing the same and methods for using the same.
FILED Tuesday, September 25, 2018
APPL NO 16/140608
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 31/437 (20130101)
A61K 31/439 (20130101)
A61K 47/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682415 Kwon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Michigan)
INVENTOR(S) Glen S. Kwon (Madison, Wisconsin);  Hyunah Cho (Madison, Wisconsin)
ABSTRACT The invention provides a drug delivery system for a combination of therapeutic agents. The system includes a water soluble biodegradable ABA-type triblock copolymer that possesses thermosensitive gelation properties. The system can form a stable thermogel that includes a combination of therapeutic agents including, for example, rapamycin, paclitaxel, and 17-AAG. After administration to a subject, the drugs are released at a controlled rate from the thermogel, which biodegrades into non-toxic components. The polymer system can also function to increase the solubility and stability of drugs in the composition.
FILED Tuesday, July 22, 2014
APPL NO 14/337929
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/395 (20130101)
A61K 31/395 (20130101)
A61K 31/436 (20130101)
A61K 31/436 (20130101)
A61K 47/34 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682422 Saltzman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) W. Mark Saltzman (New Haven, Connecticut);  Junwei Zhang (New Haven, Connecticut);  Jiangbing Zhou (Cheshire, Connecticut);  Zhaozhong Jiang (New Haven, Connecticut)
ABSTRACT Poly(amine-co-ester-co-ortho ester) polymers, methods of forming active agent-load nanoparticles therefrom, and methods of using the nanoparticles for drug delivery are disclosed. The nanoparticles can be coated with an agent that reduces surface charge, an agent that increases cell-specific targeting, or a combination thereof. Typically, the loaded nanoparticles are less toxic, more efficient at drug delivery, or a combination thereof compared to a control or other transfection reagents.
FILED Wednesday, November 18, 2015
APPL NO 15/527285
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101)
A61K 9/5146 (20130101)
A61K 31/7088 (20130101)
A61K 47/34 (20130101)
A61K 47/593 (20170801)
A61K 47/6935 (20170801)
A61K 48/0041 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/685 (20130101)
C08G 63/6856 (20130101)
C08G 2650/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682424 Fishell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Gordon Fishell (Larchmont, New York);  Jordane Dimidschstein (Seraing, Belgium)
ABSTRACT Provided are compositions and methods for prophylaxis and/or therapy of disorders that involve seizures. The compositions and methods relate to a recombinant adeno-associated virus (rAAV) comprising a I56i enhancer sequence, and a sequence encoding hM3Dq modified muscarinic receptor (Gq-DREADD). The method includes introducing the rAAV into interneurons of an individual such that Gq-DREADD is expressed in interneurons of the individual. The method can further comprise administering to the individual an agonist of the Gq-DREADD, such for reducing or preventing seizures.
FILED Thursday, March 31, 2016
APPL NO 15/561547
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/1796 (20130101)
A61K 48/0066 (20130101) Original (OR) Class

Peptides
C07K 14/705 (20130101)
C07K 14/723 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2750/14121 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/008 (20130101)
C12N 2830/30 (20130101)
C12N 2830/42 (20130101)
C12N 2830/48 (20130101)
C12N 2830/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682425 Zanetti
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Maurizio Zanetti (La Jolla, California)
ABSTRACT Provided are engineered B lymphocytes modified to express one or several different types of microRNAs or anti-miRs where in one embodiments the lymphocytes contain multiple copy numbers of nucleic acids encoding the one or several different types of miRs or anti-miRs. Provided are compositions and methods for treating, ameliorating, or preventing a cancer cell, a breast cancer cell or a triple negative breast cancer, or a breast cancer cell that tests negative for estrogen receptors, progesterone receptors, or HER2, comprising or by administering a composition, formulation or pharmaceutical composition comprising a microRNA or anti-miR. Provided are methods for treating an inflammation, a disease, a condition, infection or cancer capable of being treated by modulation or inhibition or expression of an miRNA or anti-miRs by administering to an individual in need thereof a B lymphocyte that secretes a microRNA or anti-miR, or a B lymphocyte supernatant, extracellular vesicle or exosome having a microRNA or anti-miR.
FILED Thursday, December 14, 2017
APPL NO 15/841709
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/5068 (20130101)
A61K 9/5176 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 31/7105 (20130101)
A61K 35/17 (20130101)
A61K 48/0066 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0635 (20130101)
C12N 15/85 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682442 Puleo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) David Puleo (Lexington, Kentucky);  Todd Milbrandt (Lexington, Kentucky);  James Zach Hilt (Lexington, Kentucky);  Paul Fisher (Lexington, Kentucky);  Vishwas Talwalkar (Lexington, Kentucky)
ABSTRACT The present invention relates to an injectable system combining a hydrogel, a bioceramic and a degradable matrix that provides for sustained drug delivery and structural support to recovering tissue, such as bone and the periodontium.
FILED Friday, April 03, 2015
APPL NO 14/678479
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 31/65 (20130101)
A61K 31/366 (20130101)
A61K 31/663 (20130101)
A61K 47/36 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/12 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101) Original (OR) Class
A61L 2300/602 (20130101)
A61L 2400/06 (20130101)
A61L 2430/02 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682490 Tsai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Li-Huei Tsai (Cambridge, Massachusetts);  Emery Brown (Brookline, Massachusetts);  Hannah Iaccarino (Somerville, Massachusetts);  Anthony James Martorell (Cambridge, Massachusetts);  Chinnakkaruppan Adaikkan (Somerville, Massachusetts)
ABSTRACT A method includes administering a non-invasive stimulus to a subject having a frequency of about 35 Hz to about 45 Hz to induce synchronized gamma oscillations in at least one brain region of the subject.
FILED Thursday, April 04, 2019
APPL NO 16/375393
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 23/00 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/0022 (20130101)
A61M 2021/0027 (20130101)
A61M 2021/0044 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 5/0618 (20130101)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0662 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683270 Kunos et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) George Kunos (Bethesda, Maryland);  Malliga Iyer (Germantown, Maryland);  Resat Cinar (Bethesda, Maryland);  Kenner C. Rice (Bethesda, Maryland)
ABSTRACT A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold.
FILED Thursday, August 10, 2017
APPL NO 15/674365
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 231/06 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 403/12 (20130101)
C07D 409/12 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683272 Ray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Sangeeta Ray (Ellicott City, Maryland);  Martin G. Pomper (Baltimore, Maryland);  Thomas J. Meade (Evanston, Illinois);  Ronnie C. Mease (Fairfax, Virginia);  Ying Chen (Timmonium, Maryland);  Xing Yang (Baltimore, Maryland);  Matthew Rotz (Carlsbad, California)
ABSTRACT Low-molecular weight gadolinium (Gd)-based MR contrast agents for PSMA-specific Ti-weighted MR imaging are disclosed. The (Gd)-based MR contrast agents exhibit high binding affinity for PSMA and exhibit specific Ti contrast enhancement at PSMA+ cells. The PSMA-targeted Gd-based MR contrast agents can be used for PSMA-targeted imaging in vivo. 86Y-labeled PSMA-binding ureas also are provided, wherein the PSMA-binding ureas also are suitable for use with other radiotherapeutics.
FILED Wednesday, May 06, 2015
APPL NO 15/309009
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0002 (20130101)
A61K 49/12 (20130101)
A61K 49/106 (20130101)
A61K 49/108 (20130101)
A61K 51/06 (20130101)
A61K 51/0402 (20130101)
A61K 51/0482 (20130101)
A61K 51/0497 (20130101)

Heterocyclic Compounds
C07D 257/02 (20130101) Original (OR) Class
C07D 403/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683277 Jacobson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Kenneth A. Jacobson (Silver Spring, Maryland);  Anna Junker (Wallenhorst, Germany);  Elisa Uliassi (Bologna, Italy);  Evgeny Kiselev (Rockville, Maryland)
ABSTRACT Described are compounds, which are antagonists of the P2Y14 receptor, for example, a compound of formula (I) in which ring A, R1, R2, R3, and n are as described herein. Also provided are dendron conjugates comprising the compounds, and methods of using the compounds, including a method of treating a disorder, such as inflammation, diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, a condition associated with metabolic syndrome, and asthma, and a method of antagonizing P214 receptor activity in a cell.
FILED Friday, September 23, 2016
APPL NO 15/762852
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 211/18 (20130101)
C07D 401/06 (20130101)
C07D 401/10 (20130101) Original (OR) Class
C07D 401/14 (20130101)
C07D 405/14 (20130101)
C07D 409/14 (20130101)
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683288 Leighton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) James Leighton (New York, New York);  Stephen Ho (New York, New York);  Corinne Foley (New York, New York)
ABSTRACT A compound having the structure:
FILED Friday, July 22, 2016
APPL NO 15/747313
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 313/00 (20130101)
C07D 405/06 (20130101)
C07D 413/06 (20130101)
C07D 417/04 (20130101)
C07D 417/06 (20130101) Original (OR) Class
C07D 493/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683316 Kash et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Washington, District of Columbia);  TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) John C. Kash (Potomac, Maryland);  Jeffery K. Taubenberger (Springfield, Virginia);  Rodney L. Levine (Rockville, Maryland);  Susan Doctrow (Arlington, Massachusetts)
ABSTRACT The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
FILED Friday, November 09, 2012
APPL NO 14/357556
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 13/005 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683318 Burke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Martin D. Burke (Champaign, Illinois);  Brice E. Uno (Highland Park, Illinois);  Souvik Rakshit (Uluberia, India)
ABSTRACT Disclosed is a simplified, readily scalable series of individual methods that collectively constitute a method for the synthesis of C2′epiAmB, an efficacious and reduced-toxicity derivative of amphotericin B (AmB), beginning from AmB. Also provided are various compounds corresponding to intermediates in accordance with the series of methods.
FILED Monday, October 01, 2018
APPL NO 16/148255
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 17/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683333 Raleigh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Daniel Raleigh (Stony Brook, New York);  Hui Wang (East Setauket, New York);  Ping Cao (New York, New York);  Andisheh Abedini (New York, New York)
ABSTRACT Isolated non-naturally occurring, mutant-human islet amyloid polypeptides (hIAPP) are disclosed. These polypeptides can be formulated or co-formulated at physiological pH, which enable the polypeptides of the instant disclosure to be delivered to a subject having an amyloid-based disease in a single injection with an insulin agent. Methods and compositions for treating amyloid-based disease in a subject in need thereof, by administering an effective amount of an isolated, mutant-hIAPP polypeptide, including formulations or co-formulations thereof are also disclosed.
FILED Wednesday, July 11, 2018
APPL NO 16/032328
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/22 (20130101)
A61K 38/28 (20130101)
A61K 38/28 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/001 (20130101)
C07K 14/575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683347 Mirza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) XOMA Technology Ltd. (Emeryville, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) XOMA Technology Ltd. (Emeryville, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Amer M. Mirza (San Francisco, California);  Rosemary J. Akhurst (Tiburon, California);  Ou Li (Dublin, California)
ABSTRACT The present disclosure relates, in general, to combination therapy using an inhibitor of transforming growth factor beta (TGFβ) and an inhibitor of programmed cell death protein 1 (PD-1) for treating cancer or preventing recurrence of cancer diseases such as lung cancer, prostate cancer, breast cancer, hepatocellular cancer, esophageal cancer, colorectal cancer, pancreatic cancer, bladder cancer, kidney cancer, ovarian cancer, stomach cancer, fibrotic cancer, glioma and melanoma, and metastases thereof.
FILED Monday, December 17, 2018
APPL NO 16/222725
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/57 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 16/2818 (20130101)
C07K 2317/51 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683361 Banchereau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) Jacques F. Banchereau (Montclair, New Jersey);  Gerard Zurawski (Midlothian, Texas);  Sandra Zurawski (Midlothian, Texas);  SangKon Oh (Baltimore, Maryland)
ABSTRACT The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
FILED Thursday, September 27, 2018
APPL NO 16/143995
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 2039/6056 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/2878 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/74 (20130101)
C07K 2317/80 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2317/626 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16222 (20130101)
C12N 2740/16322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683362 Pastan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Ira H. Pastan (Potomac, Maryland);  John Weldon (Columbia, Maryland);  Richard Beers (Rockville, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Ira H. Pastan (Potomac, Maryland);  John Weldon (Columbia, Maryland);  Richard Beers (Rockville, Maryland)
ABSTRACT Mesothelin is a differentiation antigen present on the surface of ovarian cancers, mesotheliomas and several other types of human cancers. Because among normal tissues, mesothelin is only present on mesothelial cells, it represents a good target for antibody mediated delivery of cytotoxic agents. The present invention is directed to improved recombinant immunotoxins comprising anti-mesothelin antibodies, including Fv molecules with particularly high affinity for mesothelin, and a Pseudomonas Exotoxin moiety which has been modified to reduce its immunogenicity and protease sensitivity and providing a better cytotoxicity for cells which express mesothelin. The RITs are well-suited for the treatment of cancers of the ovary, stomach, squamous cells, mesotheliomas and other malignant cells expressing mesothelin.
FILED Friday, May 04, 2012
APPL NO 14/115131
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 47/6829 (20170801)
A61K 47/6851 (20170801)

Peptides
C07K 14/21 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 2317/56 (20130101)
C07K 2319/32 (20130101)
C07K 2319/50 (20130101)
C07K 2319/55 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683379 Anderson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel Griffith Anderson (Framingham, Massachusetts);  Eric Andrew Appel (Cambridge, Massachusetts);  Yizhou Dong (Dublin, Ohio);  Robert S. Langer (Newton, Massachusetts);  Benjamin C. Tang (Cambridge, Massachusetts);  Omid Veiseh (Cambridge, Massachusetts);  Weiheng Wang (Bedford, Massachusetts);  Matthew J. Webber (Cambridge, Massachusetts);  Kun Xue (Cambridge, Massachusetts)
ABSTRACT Described herein are polymers, polymeric gels, or a composition thereof, for drug delivery. The polymers, which include boronic-acid containing moieties (e.g.,
and polyol-containing moieties (e.g.,
are prepared by free-radical polymerization and can self-assemble into polymeric gels such as hydrogels. Also provided are methods or preparing the polymers, kits involving the polymers and/or polymeric gels or a composition thereof, for use as materials or delivery applications of an agent to a subject.
FILED Wednesday, March 23, 2016
APPL NO 15/078685
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/32 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/28 (20130101)
C08F 8/28 (20130101)
C08F 8/28 (20130101)
C08F 8/28 (20130101)
C08F 120/56 (20130101)
C08F 120/60 (20130101)
C08F 120/60 (20130101)
C08F 130/06 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 220/60 (20130101)
C08F 230/06 (20130101) Original (OR) Class
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 230/06 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2220/603 (20130101)
C08F 2800/10 (20130101)
C08F 2810/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683476 Costa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York)
INVENTOR(S) Kevin David Costa (New York, New York);  Timothy James Cashman (New York, New York);  Peter Constantine Backeris (Union City, New Jersey)
ABSTRACT A bioreactor system for preparing a cardiac organoid chamber and for subsequent testing thereof is described herein and shown in the exemplary drawing figures. The bioreactor system includes a first vessel having a hollow interior and an open top. A first cover is mated with the open top of the first vessel. The first cover has a first opening formed therein. The system further includes a cannula having a lumen that extends from an open first end to an open second end. The cannula is disposed within the first opening of the first cover such that a portion of the cannula lies below the first cover and for insertion into the hollow interior of the first vessel. A porous ring is coupled to the cannula at or proximate the open second end thereof. The system also includes a balloon catheter having an inflatable balloon at a distal end of a catheter shaft. The balloon catheter is adapted to pass through the lumen of the cannula when the balloon is in a deflated state. The balloon catheter is axially adjustable within the lumen to allow the balloon in an inflated state to be disposed adjacent: (1) the open second end of the cannula; and (2) the porous ring for preparing the cardiac organoid chamber about the inflated balloon and porous ring. The cannula and porous ring construction and combination allows for the balloon to be deflated and removed from the lumen of the cannula while the engineered cardiac organoid chamber remains attached to the porous ring. This permits the testing of organoid pump function, such as organoid pressure and volume characteristics, without having to transfer the engineered cardiac organoid from one tool (e.g., an incubation tool) to another tool (e.g., a functional testing apparatus).
FILED Friday, May 29, 2015
APPL NO 15/314870
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101) Original (OR) Class
C12M 23/00 (20130101)
C12M 23/26 (20130101)
C12M 23/38 (20130101)
C12M 35/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683490 Chavez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Alejandro Chavez (New York, New York);  Frank J. Poelwijk (Dallas, Texas);  George M. Church (Brookline, Massachusetts)
ABSTRACT Methods of making mutant Cas9 proteins are described.
FILED Thursday, June 13, 2019
APPL NO 16/440241
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)

Enzymes
C12Y 301/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 2333/922 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683498 Armstrong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) COFACTOR GENOMICS, INC. (St. Louis, Missouri)
ASSIGNEE(S) COFACTOR GENOMICS, INC. (St. Louis, Missouri)
INVENTOR(S) Jon R Armstrong (St. Louis, Missouri);  Jeffrey F Hiken (St. Louis, Missouri)
ABSTRACT Provided herein are methods of amplifying nucleic acids. In particular, methods are provided for amplifying circular RNA molecules. In certain embodiments, circular DNA molecules for amplification are generated from circular RNA molecules.
FILED Friday, May 20, 2016
APPL NO 15/575681
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Corsets; Brassieres
A41C 3/02 (20130101)
A41C 3/0064 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683506 Zu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE METHODIST HOSPITAL SYSTEM (Houston, Texas)
ASSIGNEE(S)
INVENTOR(S) Youli Zu (Bellaire, Texas)
ABSTRACT Disclosed are compositions and methods relating to nucleic acid aptamers that specifically target CD117 protein and also selective binding to CD117-expressing cells. The ligand-drug conjugates specifically target CD117-expressing cells and subsequently internalize into the cells, leading apoptosis, growth inhibition, and death of cells of interest and no off-target toxicity to CD117-negative normal cells.
FILED Friday, April 08, 2016
APPL NO 15/565667
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/475 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
C12N 2310/351 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57407 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683507 Xiao et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Yi Xiao (Miami, Florida);  Haixiang Yu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Miami, Florida);  Haixiang Yu (Miami, Florida)
ABSTRACT The subject invention provides methods, assays, and products for detecting small molecules in a sample, in particular, in both clinical and field settings. The method for detecting a small-molecule target, preferably, a synthetic cathinone in a sample comprises contacting the sample with an aptamer-based sensor selective for the small-molecule target, and detecting the small-molecule target in the sample. Specifically, the method utilizes an aptamer-based sensor comprising a dye binding to a three-way junction binding domain of an aptamer. Binding of small-molecule target to the aptamer displaces the dye, generating a spectroscopic signal that can be used for detection of the small-molecule target and quantitative measurement of the target concentration.
FILED Tuesday, February 20, 2018
APPL NO 15/900061
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 225/10 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 23/0066 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
C12N 2310/3517 (20130101)
C12N 2320/13 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683510 Boyden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Edward S. Boyden (Cambridge, Massachusetts);  Katarzyna P. Adamala (Cambridge, Massachusetts);  Daniel A. Martin-Alarcon (Cambridge, Massachusetts)
ABSTRACT The invention, in some aspects relates to compositions comprising synthetic minimal cells (SMCs) and use of SMCs, pluralities of SMCs in relation to engineering genetic circuit interactions.
FILED Sunday, February 12, 2017
APPL NO 15/430502
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683534 Stevens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) BioSpyder Technologies, Inc. (Carlsbad, California)
ASSIGNEE(S) BioSpyder Technologies, Inc. (Carlsbad, California)
INVENTOR(S) Anthony Stevens (San Diego, California);  Bruce Seligmann (Tuscon, Arizona);  Joanne M. Yeakley (Encinitas, California);  Joel McComb (Rancho Santa Fe, California)
ABSTRACT Ligation assays in liquid phase for detecting nucleic acid sequences.
FILED Thursday, December 22, 2016
APPL NO 15/387650
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6827 (20130101) Original (OR) Class
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6827 (20130101)
C12Q 2521/307 (20130101)
C12Q 2521/319 (20130101)
C12Q 2521/325 (20130101)
C12Q 2521/325 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/161 (20130101)
C12Q 2525/161 (20130101)
C12Q 2525/185 (20130101)
C12Q 2525/185 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/197 (20130101)
C12Q 2525/207 (20130101)
C12Q 2533/101 (20130101)
C12Q 2533/101 (20130101)
C12Q 2533/107 (20130101)
C12Q 2533/107 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2561/125 (20130101)
C12Q 2563/149 (20130101)
C12Q 2565/629 (20130101)
C12Q 2565/629 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683544 Cairns et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Nigel J. Cairns (St. Louis, Missouri);  Robert H. Baloh (St. Louis, Missouri);  Alan Pestronk (St. Louis, Missouri);  Michael A. Gitcho (St. Louis, Missouri);  Alison M. Goate (St. Louis, Missouri)
ABSTRACT The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
FILED Tuesday, November 08, 2016
APPL NO 15/346268
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683552 McCarroll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE INC. (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) Presidents and Fellows of Harvard College (Cambridge, Massachusetts);  The Broad Institute, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Steven Andrew McCarroll (Cambridge, Massachusetts);  Giulio Genovese (Cambridge, Massachusetts)
ABSTRACT The present invention relates to clonal expansion of somatic cells in subjects, and acquired selective advantage of cell clones during the lifetime of a subject. In particular, the invention relates to methods for predicting the development of cancer based on the observation of specific genetic mutations in somatic cell clones, as well as to methods for treating or preventing cancer in a subject, in which clonal expansion of cells comprising specific modifications is observed.
FILED Monday, November 23, 2015
APPL NO 15/528807
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/91017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683554 Kennedy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Richard B. Kennedy (Rochester, Minnesota);  Gregory A. Poland (Marco Island, Florida);  Inna G. Ovsyannikova (Rochester, Minnesota);  Iana H. Haralambieva (Rochester, Minnesota)
ABSTRACT This document provides methods and materials involved in using measles viruses. For example, methods and materials for identifying mammals (e.g., humans) likely to respond to standard measles virus vaccines or standard measles virus-based therapies as well as methods and materials for identifying mammals (e.g., humans) unlikely to respond to standard measles virus vaccines or standard measles virus-based therapies are provided.
FILED Tuesday, February 27, 2018
APPL NO 15/907056
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/165 (20130101)
A61K 2039/572 (20130101)
A61K 2039/575 (20130101)
A61K 2039/55588 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/12 (20180101)
A61P 31/14 (20180101)
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/18434 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683558 Thomas et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland)
ASSIGNEE(S) THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETRARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland)
INVENTOR(S) Jennifer Thomas (Atlanta, Georgia);  Xin Wang (Lilburn, Georgia);  Cynthia Hatcher (Atlanta, Georgia);  Raydel Anderson (Lawrenceville, Georgia);  Mary Jordan Theodore (Atlanta, Georgia);  Leonard W. Mayer (Decatur, Georgia)
ABSTRACT A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
FILED Tuesday, January 31, 2017
APPL NO 15/420836
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 1/701 (20130101)
C12Q 2600/16 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684240 Sorgenfrei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Trustees Of Columbia University In the City of New York (New York, New York)
ASSIGNEE(S) The Trustees Of Columbia University In the City of New York (New York, New York)
INVENTOR(S) Sebastian Sorgenfrei (Portland, Oregon);  Kenneth L. Shepard (Ossining, New York);  Chien-Yang Chiu (Goleta, California);  Colin Nuckolls (New York, New York);  Steven Warren (White Plains, New York)
ABSTRACT A method for single-molecule detection is provided and uses a carbon nanotube having a probe entity attached thereto to define a first state of the carbon nanotube. The carbon nanotube is introduced to a target entity to define a second state of the carbon nanotube. The electrical conductance of the carbon nanotube in the first and second states is compared to detect the presence of a biomolecular entity. A system for single-molecule detection including a carbon nanotube is also provided.
FILED Thursday, December 28, 2017
APPL NO 15/857010
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/041 (20130101) Original (OR) Class
G01N 27/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684250 Yun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Minhee Yun (Pittsburgh, Pennsylvania);  David Schwartzman (Pittsburgh, Pennsylvania);  Jiyong Huang (Pittsburgh, Pennsylvania)
ABSTRACT A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire.
FILED Monday, April 25, 2016
APPL NO 15/137921
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4145 (20130101) Original (OR) Class
G01N 27/4146 (20130101)
G01N 33/552 (20130101)
G01N 33/5438 (20130101)
G01N 33/54366 (20130101)
G01N 33/54373 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/762 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684274 Adzhubei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia);  Alexei Adzhubei (Moscow, Russian Federation)
ASSIGNEE(S) THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONLLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia)
INVENTOR(S) Alexei Adzhubei (Moscow, Russian Federation);  Michael Bukrinsky (Potomac, Maryland);  Ruth Hunegnaw (Arlington, Virginia)
ABSTRACT The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
FILED Thursday, January 12, 2017
APPL NO 16/069483
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/18 (20130101)
A61K 31/167 (20130101)
A61K 31/404 (20130101)

Acyclic or Carbocyclic Compounds
C07C 223/06 (20130101)
C07C 381/00 (20130101)

Heterocyclic Compounds
C07D 209/56 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/502 (20130101)
G01N 33/5041 (20130101) Original (OR) Class
G01N 2333/163 (20130101)
G01N 2333/4727 (20130101)
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684287 Tang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Shaogeng Tang (Stanford, California);  Peter S. Kim (Stanford, California)
ABSTRACT Variants of human PD-1 comprising one or more of amino acid substitutions in residues corresponding to N74, T76 and A132 of SEQ ID NO:1 are described. Also described are structures, obtained using X-ray crystallography, of the human PD-1/PD-L2 complex and mutant PD-1 variants. The structures of human PD-1 described in the present disclosure are useful in drug discovery, including small-molecule drug discovery. Accordingly, methods of using the structures in drug discovery are also described.
FILED Monday, February 10, 2020
APPL NO 16/786409
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101) Original (OR) Class
G01N 2333/70521 (20130101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/30 (20190201)
G16C 20/64 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684292 Bowler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) NATIONAL JEWISH HEALTH (Denver, Colorado)
ASSIGNEE(S) National Jewish Health (Denver, Colorado)
INVENTOR(S) Russell P. Bowler (Denver, Colorado)
ABSTRACT Disclosed are methods of identifying, predicting and treating subjects at risk for exacerbation or the presence of a respiratory disease, by detecting expression levels of one or more proteins associated with the respiratory disease.
FILED Tuesday, March 13, 2018
APPL NO 15/919560
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/50 (20130101)
G01N 2800/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684337 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Mental Health (NIMH)
APPLICANT(S) Xiaoping Wu (Shoreview, Minnesota);  Pierre-Francois Van De Moortele (Minneapolis, Minnesota);  Sebastian Schmitter (Minneapolis, Minnesota);  Kamil Ugurbil (Minneapolis, Minnesota);  Edward Auerbach (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Xiaoping Wu (Shoreview, Minnesota);  Pierre-Francois Van De Moortele (Minneapolis, Minnesota);  Sebastian Schmitter (Minneapolis, Minnesota);  Kamil Ugurbil (Minneapolis, Minnesota);  Edward Auerbach (Minneapolis, Minnesota)
ABSTRACT A method for designing one or more multichannel, multiband radio frequency (“RF”) pulses for use with a magnetic resonance imaging (“MRI”) system is provided. The method includes determining a number of RF amplitude modulations and a number of RF phase modulations for each channel in a multichannel RF coil by minimizing an objective function that includes a complex-valued vector. The objective function also contains a system matrix that accounts for both a spatial sensitivity profile of each channel in the multichannel RF coil and a magnetic field map for each excitation band in the multiband RF pulse.
FILED Friday, January 24, 2014
APPL NO 14/762093
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/36 (20130101)
G01R 33/246 (20130101)
G01R 33/543 (20130101) Original (OR) Class
G01R 33/3607 (20130101)
G01R 33/4818 (20130101)
G01R 33/4835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684339 An et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S) Hongyu An (St. Louis, Missouri);  Meher Juttukonda (Nashville, Tennessee);  Cihat Eldeniz (St. Louis, Missouri);  Yasheng Chen (St. Louis, Missouri)
ABSTRACT Systems and methods for producing pseudo-CT images using a dual flip angle multi-echo ultra-short echo time (DUFA-MUTE) MRI method are disclosed. The DUFA-MUTE MRI imaging method includes obtaining MR signals according to a DUFA-MUTE MRI sequence that includes first and second multiple ultrashort echo time (MUTE) sequence characterized by first and second flip angles FA1/FA2, and in which both MUTE sequences obtain MR signals at first and second echo times TE1/TE2. HU values are assigned to each imaged voxel based on each voxel's R1 value calculated from the MR signals, as well as each voxel's assigned tissue type. The imaged voxels and assigned HU values are combined to produce a pseudo-CT image. Pseudo-CT images optionally form the basis for attenuation maps suitable for use in combined PET/MRI systems and/or electron density maps suitable for use in radiation therapy systems.
FILED Tuesday, January 16, 2018
APPL NO 15/872407
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101)
A61B 5/055 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1039 (20130101)
A61N 2005/1055 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4812 (20130101)
G01R 33/4816 (20130101)
G01R 33/5608 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684344 Daniel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Bruce L. Daniel (Stanford, California);  Brian A. Hargreaves (Menlo Park, California);  Subashini Srinivasan (Palo Alto, California)
ABSTRACT Improved motion correction for magnetic resonance imaging is provided. An MR imaging method provides a first sequence of MR images and a second sequence of MR images where: 1) the two sequences are inherently spatially co-registered and synchronous with each other; 2) the first sequence includes signal variation due to one or more causes other than motion or deformation; and 3) the second sequence does not include the signal variation of the first sequence. In this situation, the second sequence can be used to perform motion correction for the first sequence. One example of this approach is Dixon MR imaging, where the water images are the first sequence and the fat images are the second sequence.
FILED Friday, March 31, 2017
APPL NO 15/476810
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4828 (20130101)
G01R 33/5601 (20130101)
G01R 33/56509 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684417 Backman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  AMERICAN BIOOPTICS, LLC (Chicago, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  AMERICAN BIOOPTICS, LLC (Chicago, Illinois)
INVENTOR(S) Vadim Backman (Chicago, Illinois);  Jeremy D. Rogers (Madison, Wisconsin);  Nikhil N. Mutyal (Evanston, Illinois);  Bradley Gould (Evanston, Illinois);  Andrew J. Radosevich (Evanston, Illinois);  The Quyen Nguyen (Evanston, Illinois)
ABSTRACT Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.
FILED Thursday, February 01, 2018
APPL NO 15/886431
ART UNIT 2874 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)
A61B 5/0084 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/474 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/262 (20130101) Original (OR) Class
G02B 6/3807 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684458 Chung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jaebum Chung (Pasadena, California);  Changhuei Yang (South Pasadena, California)
ABSTRACT Aberration-corrected incoherent imaging methods and systems that can acquire a sequence of coherent images and an incoherent image of a specimen, implement an embedded pupil function recovery process in junction with Fourier ptychographic technique to construct an improved resolution image and pupil function of the imaging system using the sequence of coherent images, determine an optical transfer function based on the estimated pupil function, and remove the aberration from the incoherent image using a deconvolution process to generate an aberration-corrected incoherent image.
FILED Friday, March 11, 2016
APPL NO 15/068389
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/008 (20130101)
G02B 21/0072 (20130101) Original (OR) Class
G02B 21/0076 (20130101)
G02B 27/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685045 Orlova et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Darya Y. Orlova (Menlo Park, California);  Stephen W. Meehan (Burnaby, Canada);  Wayne A. Moore (San Francisco, California);  Guenther Walther (Mountain View, California);  David R. Parks (San Francisco, California);  Leonore A. Herzenberg (Stanford, California);  Connor Meehan (Burnaby, Canada)
ASSIGNEE(S) The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Darya Y. Orlova (Menlo Park, California);  Stephen W. Meehan (Burnaby, Canada);  Wayne A. Moore (San Francisco, California);  Guenther Walther (Mountain View, California);  David R. Parks (San Francisco, California);  Leonore A. Herzenberg (Stanford, California);  Connor Meehan (Burnaby, Canada)
ABSTRACT Some embodiments provide methods, systems and computer-readable media that employ adaptive binning and dissimilarity scores based on a quadratic form distance for multidimensional data for matching clusters in data corresponding to different sample. Some embodiments provide methods, systems and computer-readable media for rendering a first interactive display including a two-dimensional plot of at least a portion of a multidimensional data set and a corresponding second interactive display including a plurality of single parameter charts or histograms, each displaying information corresponding to one-dimensional measurements of a different parameter in the multidimensional data set.
FILED Monday, July 17, 2017
APPL NO 15/652194
ART UNIT 2154 — Data Bases & File Management
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1429 (20130101)
G01N 15/1459 (20130101)
G01N 2015/0065 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1402 (20130101)
G01N 2015/1477 (20130101)

Electric Digital Data Processing
G06F 3/0482 (20130101)
G06F 3/04847 (20130101)
G06F 16/283 (20190101)
G06F 16/287 (20190101) Original (OR) Class
G06F 16/24575 (20190101)

Image Data Processing or Generation, in General
G06T 11/206 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685114 Scaife et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Walter N. Scaife (Gainesville, Florida);  Patrick G. Traynor (Gainesville, Florida);  Henry Carter (Bryn Mawr, Pennsylvania);  Kevin Butler (Gainesville, Florida)
ABSTRACT Techniques and systems are described for detecting malware's bulk transformation of a user's data before the malware is able to complete the data transformation. Included are methods and systems for enabling malware detection by monitoring the file operations of a computer application or process for particular kinds of suspicious data transformation indicators. Indicators include primary indicators, such as file-type signature changes, notable changes in file data entropy, and out-of-range similarity measurements between the read and write versions of file data, as well as secondary indicators, such as a large number of file deletions and a large reduction in the number of file-types written versus read by a process over time. When indicators are triggered by a process, an adjustment to the process' malware score is made; in the event that the process' malware score reaches a malware detection threshold, the process is marked as malware and appropriate actions are taken.
FILED Friday, September 23, 2016
APPL NO 15/759014
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/565 (20130101)
G06F 21/566 (20130101) Original (OR) Class
G06F 21/6218 (20130101)
G06F 2221/034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685142 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) XiaoFeng Wang (Bloomington, Indiana);  Kan Yuan (Bloomington, Indiana);  Xiaoyong Zhou (Sunnyvale, California);  Muhammad Naveed (Urbana, Illinois);  Soteris Demetriou (Urbana, Illinois);  Carl Gunter (Urbana, Illinois)
ABSTRACT The present disclosure provides a security enhanced channel control system useable on a wireless device comprising a policy module including at least one processor and memory, the policy module configured to store, in the memory, one or more security policies and apply a compliance check to a first system layer and a second system layer; and a first policy base stored in the memory of the policy module, the first policy base being associated with a mandatory access control (“MAC”) base and defining one more security polices for access to a plurality of channels associated with the first and second system layers. The policy module cooperates with the first policy base to establish one or more access control rules that are applied to at least one of the plurality of channels to preclude an unauthorized application from accessing at least one of the channels.
FILED Tuesday, February 02, 2016
APPL NO 15/547402
ART UNIT 2493 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6281 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10682081 Hirshfield et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Outerfacing Technology LLC (Boulder, Colorado)
ASSIGNEE(S) Outerfacing Technology LLC (Boulder, Colorado)
INVENTOR(S) Leanne Hirshfield (Boulder, Colorado);  Christopher M. Meier (Lake Mills, Wisconsin)
ABSTRACT A method, system, and computer program product include aiming a light source at an object, where the light source is communicatively coupled to the processor, and where the light source and the image capture device are both positioned at pre-defined distances from a the object and are not in contact with the object. The processor enables the image capture device, to capture measurements of reflected light, where the reflected light comprises the light from the source as the light is reflected out of the object, where the image capture device is communicatively coupled to the processor, and where an image comprises the measurements. The processor obtains the image and locates data indicating a center of the light source in the image. The processor extracts intensities of the reflected light at a pixel location measured to be a predefined distance from the center of the light source in the image.
FILED Wednesday, December 21, 2016
APPL NO 15/386488
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/0075 (20130101)
A61B 5/4064 (20130101)
A61B 5/14553 (20130101) Original (OR) Class
A61B 2562/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682147 Grant et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of America, as represented by the Secretary of Defense (Washington, District of Columbia)
INVENTOR(S) Gerald Grant (Goshen, Kentucky);  Peter Liacouras (North Potomac, Maryland);  Chad Gordon (Lutherville, Maryland);  Ryan Murphy (Columbia, Maryland);  Mehran Armand (Fulton, Maryland)
ABSTRACT A surgical guide assembly having an attachment device configured to be coupled to a bone. A cut location indicator is coupled to the attachment device. The cut location indicator identifies a location where the bone is to be cut. An arm is coupled to the attachment device, the cut location indicator, or both. A support structure is coupled to the arm. The support structure is configured to have a trackable feature coupled thereto.
FILED Monday, November 24, 2014
APPL NO 15/100252
ART UNIT 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/15 (20130101) Original (OR) Class
A61B 17/176 (20130101)
A61B 17/1695 (20130101)
A61B 17/1739 (20130101)
A61B 17/8085 (20130101)
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 2034/105 (20160201)
A61B 2034/108 (20160201)
A61B 2034/2051 (20160201)
A61B 2034/2055 (20160201)
A61B 2034/2065 (20160201)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2803 (20130101)

Electric Digital Data Processing
G06F 19/3481 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/50 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/26 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682397 Auerbach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Duke University (Durham, North Carolina)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Duke University (Durham, North Carolina)
INVENTOR(S) Benjamin David Auerbach (Buffalo, New York);  Mark Firman Bear (Boston, Massachusetts);  Laura Jane Stoppel (Cambridge, Massachusetts);  Robert J. Lefkowitz (Durham, North Carolina)
ABSTRACT Disclosed herein are novel methodologies of treating fragile X syndrome and related disorders by inhibiting mGlu5-relevant signaling pathways via the reduction of β-arrestin2 protein levels or the diminution of mGlu5 and β-arrestin2 protein interactions.
FILED Wednesday, November 30, 2016
APPL NO 15/364332
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2217/15 (20130101)
A01K 2217/075 (20130101)
A01K 2217/077 (20130101)
A01K 2227/105 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101) Original (OR) Class
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/115 (20130101)
C12N 15/1138 (20130101)
C12N 2310/10 (20130101)
C12N 2310/11 (20130101)
C12N 2310/12 (20130101)
C12N 2310/14 (20130101)
C12N 2310/16 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3231 (20130101)
C12N 2310/3233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682530 Maharbiz et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michel M. Maharbiz (El Cerrito, California);  Dongjin Seo (Albany, California);  Konlin Shen (Oakland, California);  Jose M. Carmena (Berkeley, California);  Ryan Neely (El Cerrito, California);  Elad Alon (Oakland, California);  Jan Rabaey (Berkeley, California)
ABSTRACT Described herein are implantable devices configured to detect an electrophysiological signal. Certain exemplary implantable devices comprise a first electrode and a second electrode configured to engage a tissue and detect an electrophysiological signal; an integrated circuit comprising a multi-transistor circuit and a modulation circuit configured to modulate a current based on the electrophysiological signal; and an ultrasonic transducer configured to emit an ultrasonic backscatter encoding the electrophysiological signal from the tissue based on the modulated current. Also described herein are systems that include one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Further described are computer systems for operating one or more implantable devices, and methods of detecting an electrophysiological signal in a tissue.
FILED Monday, April 29, 2019
APPL NO 16/398086
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 5/076 (20130101)
A61B 5/686 (20130101)
A61B 5/4836 (20130101)
A61B 6/4258 (20130101)
A61B 8/48 (20130101)
A61B 8/085 (20130101)
A61B 8/0808 (20130101)
A61B 8/0875 (20130101)
A61B 2505/05 (20130101)
A61B 2560/0219 (20130101)
A61B 2562/12 (20130101)
A61B 2562/028 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 39/0208 (20130101)
A61M 2205/04 (20130101)
A61M 2205/825 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/372 (20130101)
A61N 1/0534 (20130101)
A61N 1/3605 (20130101)
A61N 1/3787 (20130101)
A61N 1/37205 (20130101)
A61N 5/1071 (20130101)
A61N 7/02 (20130101) Original (OR) Class
A61N 2005/1087 (20130101)
A61N 2007/0021 (20130101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/327 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/15 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682638 Rhodes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Texas State University (San Marcos, Texas)
ASSIGNEE(S) Texas State University San Marcos (San Marcos, Texas)
INVENTOR(S) Christopher P. Rhodes (San Marcos, Texas);  Jose Fernando Godinez-Salomon (Austin, Texas)
ABSTRACT In some embodiments, a method may include forming a catalytic nanoarchitecture. The method may include heating a non-catalytic metal compound within a specified temperature range and atmosphere in the presence of a catalytic metal. In some embodiments, heating the non-catalytic metal may include heating within a hydrogen-containing atmosphere. The method may include transforming a first architecture of the non-catalytic metal to a second architecture. The second architecture may include openings in the second architecture. The method may include incorporating the catalytic metal into the openings in the second architecture such that the catalytic metal is integrated into the second architecture. In some embodiments, the method may include increasing a catalytic activity of the catalytic metal by integrating the catalytic metal into the second architecture.
FILED Friday, October 20, 2017
APPL NO 15/789651
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/40 (20130101)
B01J 23/48 (20130101)
B01J 23/892 (20130101)
B01J 35/002 (20130101)
B01J 35/006 (20130101)
B01J 35/0013 (20130101)
B01J 35/023 (20130101)
B01J 35/0033 (20130101)
B01J 35/0053 (20130101)
B01J 35/1014 (20130101)
B01J 35/1057 (20130101)
B01J 35/1061 (20130101) Original (OR) Class
B01J 35/1066 (20130101)
B01J 37/08 (20130101)
B01J 37/16 (20130101)
B01J 37/0217 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2004/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682759 Oelrich
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rosemarie Yagoda Oelrich (Virginia Beach, Virginia)
ABSTRACT Typical inventive practice allocates functions between human and robot, interacting in an unmanned system. Analyses are performed of: mission system; function allocation; and, human-robot interaction automation allocation. Mission system analysis includes: identification of mission system needs, mission system integration parameters, and mission capability configuration; and, mission system report creation (at least partially based on these identifications). Function allocation analysis includes: mission activity analysis; functional allocation report creation (at least partially based on the mission activity analysis); unmanned system safety analysis; and, unmanned system safety report creation (at least partially based on the unmanned system safety analysis). Human-robot interaction automation allocation analysis includes: identification of unmanned system capabilities, unmanned system mission safety considerations, and human-robot interaction configuration; human-robot interaction test-and-evaluation plan creation (at least partially based on these identifications); human-robot interaction performance evaluation; and, human-robot interaction configuration final report creation (at least partially based on the human-robot interaction performance evaluation).
FILED Friday, October 26, 2012
APPL NO 13/662137
ART UNIT 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1656 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683060 Henry et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Christopher P. Henry (Thousand Oaks, California);  Sloan P. Smith (Calabasas, California);  David W. Shahan (Los Angeles, California);  Joseph Creecy (Malibu, California);  Jeffrey Bowles (Malibu, California);  Christopher Swanhart (Malibu, California);  Robert Walling (Malibu, California)
ABSTRACT A watercraft includes a hull having inner and outer surfaces and at least one collapsible strake coupled to the hull. The collapsible strake includes a movable skin hingedly coupled to the hull. The collapsible strake also includes a dampening element and a negative stiffness element each extending from an inner surface of the movable skin to the outer surface of the hull. The movable skin is configured to rotate between an uncollapsed configuration having a first stiffness and a collapsed configuration having a second stiffness greater than the first stiffness.
FILED Wednesday, January 02, 2019
APPL NO 16/238251
ART UNIT 3617 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 1/04 (20130101)
B63B 1/22 (20130101) Original (OR) Class
B63B 3/24 (20130101)
B63B 2001/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683083 Baltrusch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
APPLICANT(S) SURVICE Engineering Company (Belcamp, Maryland)
ASSIGNEE(S) SURVICE Engineering Company (Belcamp, Maryland)
INVENTOR(S) Robert Eric Baltrusch (Newark, Delaware);  Mark Thomas Butkiewicz (North East, Maryland);  Shawn Thomas Recker (Bel Air, Maryland);  Joel Henry Witman (Essex, Maryland)
ABSTRACT An integrated logistics asset guidance system uses a handheld housing that is programmed by a user to formulate a brief discrete message. The message is combined with a GPS coordinate captured by a GPS receiver within the housing with the message and coordinate are transmitted by a satcom transmitter within the housing using military secure encrypted communications protocols to a base station transceiver via a satellite. The transceiver retransmits the GPS coordinate and message via the satellite to a logistics asset so that the logistics asset can travel to the location indicated by the GPS coordinate, the logistics asset delivering supplies requested by the message sent.
FILED Sunday, September 01, 2019
APPL NO 16/558129
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Aeroplanes; Helicopters
B64C 19/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683107 Fuller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Jerome K. Fuller (Lake Balboa, California);  Alexander August-Schmidt (Los Angeles, California);  Geoffrey A. Maul (Huntington Beach, California);  Cody L. Shaw (Green Cove Springs, Florida)
ABSTRACT A release apparatus includes a base member and a channel having a first portion and a second portion. A first rod positioned within the first portion includes a first end portion having a first coupling device and a second end portion coupled to a first portion of a panel assembly. A second rod positioned within the channel's second portion includes a first end portion having a second coupling device such that the second coupling device is positioned proximate to the first coupling device. The second rod includes a second end portion coupled to a second portion of the panel assembly. First and second coupling devices rotate such that a linear force is generated between the first and second rods, enabling the first rod second end portion and the second rod second end portion to simultaneously release the first and second portions of the panel assembly, respectively.
FILED Friday, August 04, 2017
APPL NO 15/669175
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/66 (20130101)
B64G 1/222 (20130101) Original (OR) Class

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 1/0014 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/08 (20130101)
H01Q 1/288 (20130101)
H01Q 1/1235 (20130101)
H01Q 15/161 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 403/593 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683388 Wagener et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Kenneth B. Wagener (Gainesville, Florida);  Michael H. Bell (Gainesville, Florida)
ABSTRACT A method of carrying out a metathesis reaction includes the combination of at least one alkene or non conjugated diene with a Ruthenium-based catalyst with an cyclic(alkyl)(amino)carbene ligand to form a reaction mixture and heating the reaction mixture to a temperature of 100° C. or greater. The reaction can be an ADMET, ROMP, a metathesis ring-closure or an olefin exchange reaction.
FILED Thursday, August 16, 2018
APPL NO 15/998762
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/2278 (20130101)
B01J 2231/14 (20130101)
B01J 2231/543 (20130101)
B01J 2531/821 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101) Original (OR) Class
C08G 61/12 (20130101)
C08G 75/20 (20130101)
C08G 2261/122 (20130101)
C08G 2261/344 (20130101)
C08G 2261/418 (20130101)
C08G 2261/419 (20130101)
C08G 2261/724 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683559 Peralta-Yahya et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Pamela Peralta-Yahya (Atlanta, Georgia);  Kuntal Mukherjee (Atlanta, Georgia);  Souryadeep Bhattacharyya (Atlanta, Georgia);  Stephen Sarria (Atlanta, Georgia)
ABSTRACT Provided herein are GPCR-based chemical biosensors that can have a sensing unit, a processing unit, and a response unit that can be used to detect a chemical of interest. Also provided herein are methods of making and using the GPCR-based chemical biosensors.
FILED Monday, November 06, 2017
APPL NO 15/804639
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/81 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/92 (20130101)
G01N 33/582 (20130101)
G01N 2333/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683735 McCarthy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America As Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Daniel McCarthy (LaPlata, Maryland);  Lee Foltz (Indian Head, Maryland);  Angel Diaz (Indian Head, Maryland);  David Rivera Marchand (Alexandria, Virginia)
ABSTRACT A shaped charge includes a casing with a liner disposed therein. The liner has two spaced-apart and nested walls with each wall having an identical ogive shape. An explosive material fills a portion of the casing up to one of the walls. A loose particulate material is disposed between the walls. A blasting cap is coupled to a first axial end of the casing adjacent to the explosive material, and a sealing cap is coupled to a second axial end of the casing.
FILED Wednesday, May 01, 2019
APPL NO 16/501559
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/117 (20130101) Original (OR) Class

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 1/028 (20130101)
F42B 1/032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683760 Kaufman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of the Navy (DON)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Eleanor D. Kaufman (Cromwell, Connecticut);  Matthew A. Devore (Rocky Hill, Connecticut)
ABSTRACT A component for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, a platform having an outer surface and an inner surface that axially extend between a leading edge portion and a trailing edge portion. At least one augmentation feature is disposed on at least the leading edge portion or the trailing edge portion of the outer surface of the platform.
FILED Friday, May 15, 2015
APPL NO 14/713186
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/145 (20130101) Original (OR) Class
F01D 5/187 (20130101)
F01D 9/041 (20130101)
F01D 25/12 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/81 (20130101)
F05D 2260/2212 (20130101)
F05D 2260/2214 (20130101)
F05D 2260/22141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684213 Delbridge et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jamaal D. Delbridge (Woodbridge, Virginia);  Erick O. Satchell (Waldorf, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jamaal D. Delbridge (Woodbridge, Virginia);  Erick O. Satchell (Waldorf, Maryland)
ABSTRACT A freestanding coating membrane is fabricated and is tested for ionic transport. An adhesive liner is situated on a flat surface, paint is poured on the liner, a leveling blade is used to impart a uniform thickness to the uncured paint, the paint when completely cured is peeled from the liner, and the thickness of the resultant freestanding membrane is measured. Saline water is placed in an open-ended reservoir in communication with an assembly holding the freestanding membrane and containing deionized water. A pump causes water to circulate through the assembly via a conduit, which is connected at both ends to the assembly. The electrical conductivity of the circulating water is monitored for an appropriate duration for indication of salt concentration. The conductivity is initially low because the circulating water is originally deionized, and gradually increases commensurately with the amount of salt (e.g., chloride) ions passing through the membrane.
FILED Wednesday, April 20, 2016
APPL NO 15/133464
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 17/02 (20130101) Original (OR) Class
G01N 27/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684240 Sorgenfrei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Trustees Of Columbia University In the City of New York (New York, New York)
ASSIGNEE(S) The Trustees Of Columbia University In the City of New York (New York, New York)
INVENTOR(S) Sebastian Sorgenfrei (Portland, Oregon);  Kenneth L. Shepard (Ossining, New York);  Chien-Yang Chiu (Goleta, California);  Colin Nuckolls (New York, New York);  Steven Warren (White Plains, New York)
ABSTRACT A method for single-molecule detection is provided and uses a carbon nanotube having a probe entity attached thereto to define a first state of the carbon nanotube. The carbon nanotube is introduced to a target entity to define a second state of the carbon nanotube. The electrical conductance of the carbon nanotube in the first and second states is compared to detect the presence of a biomolecular entity. A system for single-molecule detection including a carbon nanotube is also provided.
FILED Thursday, December 28, 2017
APPL NO 15/857010
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/041 (20130101) Original (OR) Class
G01N 27/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684247 Gupta
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (Palo Alto, California)
INVENTOR(S) Chaitanya Gupta (Foster City, California)
ABSTRACT Aspects of a biosensor platform system and method are described. In one embodiment, the biosensor platform system includes a fluidic system and tunneling biosensor interface coupled to the fluidic system. The tunneling biosensor interface may include a transducing electrode array having at least one dielectric thin film deposited on an electrode array. The biosensor platform system may further include processing logic operatively coupled to the transducing electrode array. In operation, the application of an electromagnetic field at an interface between an electrode and an electrolyte in the system, for example, may result in the transfer of charge across the interface. The transfer of charge is, in turn, characterized by electromagnetic field-mediated tunneling of electrons that may be assisted by exchange of energy with thermal vibrations at the interface. Various analytes, for example, and other compositions can be identified by analysis of the transfer of charge.
FILED Wednesday, September 05, 2018
APPL NO 16/122346
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684266 Swager et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Sophie Liu (Cambridge, Massachusetts);  Graham Thomas Sazama (Chestnut Hill, Massachusetts)
ABSTRACT A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region can include a complex, and the complex can include a carbon nanotube that is functionalized by a porphyrin.
FILED Saturday, April 02, 2016
APPL NO 15/089526
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 33/12 (20130101) Original (OR) Class
G01N 33/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684324 Barrett
FUNDED BY
Department of Defense (DOD)
Office of the Secretary of Defense (OSD)
DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S) Science Applications International Corporation (Reston, Virginia)
ASSIGNEE(S) SAIC (Reston, Virginia)
INVENTOR(S) David Michael Barrett (Burtonsville, Maryland)
ABSTRACT Systems, methods, and apparatuses are described for verifying the authenticity of an integrated circuit device. An integrated test apparatus may use quiescent current and/or conducted electromagnetic interference readings to determine if a device under test matches the characteristics of an authenticated device. Deviations from the characteristics of the authenticated device may be indicative of a counterfeit device.
FILED Friday, December 13, 2019
APPL NO 16/713413
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3008 (20130101) Original (OR) Class
G01R 31/31905 (20130101)
G01R 31/318588 (20130101)

Electric Digital Data Processing
G06F 21/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684336 Vermilyea et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S) Mark Ernest Vermilyea (Schenectady, New York);  Justin Michael Ricci (Schenectady, New York);  Christina Vasil (Troy, New York);  Ek Tsoon Tan (Halfmoon, New York);  Eric William Fiveland (Schenectady, New York);  Yihe Hua (Rexford, New York);  Thomas Kwok-Fah Foo (Clifton Park, New York)
ABSTRACT An imaging device may include a patient bore to house a subject to be imaged, wherein the patient bore includes one or more bore tubes. The imaging device may also include a gradient coil surrounding, at least partially, the patient bore and a radio frequency (RF) shield located outside the one or more bore tubes. Additionally, the imaging device may include an RF coil located within at least one of the bore tubes.
FILED Wednesday, October 24, 2018
APPL NO 16/169536
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/422 (20130101) Original (OR) Class
G01R 33/3403 (20130101)
G01R 33/3856 (20130101)
G01R 33/34092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684353 Kusters, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Applied Physical Sciences Corp. (Groton, Connecticut)
ASSIGNEE(S) Applied Physical Sciences Corp. (Groton, Connecticut)
INVENTOR(S) John G. Kusters, Jr. (Groton, Connecticut);  Jason P. Rudzinsky (Groton, Connecticut);  Benjamin S. H. Connell (Groton, Connecticut);  Christopher S. Brundick (Groton, Connecticut);  Kevin Cockrell (Groton, Connecticut);  William M. Milewski (Groton, Connecticut)
ABSTRACT Systems and methods for ship motion forecasting are described herein. These ship motion forecasting systems can enable accurate real-time forecasting of waves and resultant vessel motions, and the useful displaying of such forecasts to users. In general, the ship motion forecasting systems and methods provide users with useful indications of ship motion forecasts by generating scrolling graphical representations of the ship motion forecasts. For example, the systems can be implemented to display on a first window portion a plurality of graphical representations of ship motion forecasts generated over a plurality of forecast cycles, where the graphical representations of new ship motion forecasts are added as generated, and where the graphical representations of previously generated ship motion forecasts are scrolled as new ship motion forecasts are added.
FILED Thursday, September 14, 2017
APPL NO 15/704832
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 39/14 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/04 (20130101)
G01S 7/24 (20130101) Original (OR) Class
G01S 13/50 (20130101)
G01S 13/62 (20130101)
G01S 13/86 (20130101)
G01S 13/91 (20130101)
G01S 13/605 (20130101)
G01S 13/874 (20130101)
G01S 13/937 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684522 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Faraday Technology, Inc. (Englewood, Ohio)
ASSIGNEE(S) Faraday Technology, Inc. (Englewood, Ohio)
INVENTOR(S) E. Jennings Taylor (Troy, Ohio);  Holly M. Garich (Fairborn, Ohio);  Maria E. Inman (Yellow Springs, Ohio)
ABSTRACT A system and method of operating an electrochemical mirror for reversibly controlling the propagation of electromagnetic radiation. The mirror preferably includes a first electrode transmissive substrate which is substantially transparent to the electromagnetic radiation, a second electrode, and an electrolyte containing metal ions between the pair of electrodes. A first cathodic potential is applied across the electrodes to cause the metal ions from the electrolyte to electrodeposit a mirror film on the first electrode transmissive substrate. A second anodic potential is applied across the electrodes to oxidize and strip the metallic mirror film from the first electrode transmissive electrode. After a plurality of deposition and stripping cycles, a cleaning cycle is initiated to remove undissolved reflective material on the first electrode preferably by applying a third potential across the first and second electrodes which is increased to a fourth potential and then decreased back to the third potential.
FILED Wednesday, September 05, 2018
APPL NO 16/122312
ART UNIT 2872 — Optics
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 5/18 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/155 (20130101)
G02F 1/163 (20130101)
G02F 1/1506 (20130101) Original (OR) Class
G02F 1/1525 (20130101)
G02F 2001/1555 (20130101)
G02F 2201/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684591 Burke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S) THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENT BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
INVENTOR(S) John H. Burke (Kirtland AFB, New Mexico);  Nathan D. Lemke (Albuquerque, New Mexico);  Gretchen R. Phelps (Albuquerque, New Mexico);  Kyle W. Martin (Albuquerque, New Mexico);  Benjamin K. Stuhl (Albuquerque, New Mexico)
ABSTRACT An optical atomic clock includes a fiber-coupled electro-optic modulator to phase modulate and suppress residual amplitude modulation of a frequency-doubled laser; a rubidium-enriched vapor cell configured to perform a two-photon transition of rubidium atoms to generate a fluorescence signal from the laser; and a differential lock mechanism to stabilize a frequency of the fluorescence signal to a resonance frequency of the two-photon transition of the rubidium atoms.
FILED Monday, August 06, 2018
APPL NO 16/056342
ART UNIT 2849 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/365 (20130101)
G02F 2203/56 (20130101)

Time-interval Measuring
G04F 5/14 (20130101) Original (OR) Class
G04F 5/145 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/005 (20130101)
H01S 3/13 (20130101)
H01S 3/0085 (20130101)
H01S 3/1305 (20130101)
H01S 5/142 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684858 Eyerman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Stijn Eyerman (Evergem, Belgium);  Wim Heirman (Ghent, Belgium);  Kristof Du Bois (Aalst, Belgium);  Ibrahim Hur (Portland, Oregon);  Joshua B. Fryman (Corvallis, Oregon)
ABSTRACT Disclosed embodiments relate to an indirect memory fetch (IMF) unit. In one example, an apparatus includes circuitry to fetch and decode an instruction specifying a sparse operand array including N operands, and an index array including N contiguously-addressed indices. The apparatus further includes a processing engine associated with an IMF unit to respond to the decoded instruction by initializing the IMF unit to fetch the N operands in order, probing the IMF unit to determine that a fetched operand is ready to retrieve, retrieving the fetched operand from the IMF unit, and repeating the probing and retrieving until all N operands have been retrieved. The IMF unit, independent of the processing engine, is to fetch the N contiguously-addressed indices from the index array, use the N fetched indices to calculate memory addresses for the N operands, and issue a plurality of read requests to fetch the N operands in order.
FILED Friday, June 01, 2018
APPL NO 15/996184
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3802 (20130101) Original (OR) Class
G06F 9/3818 (20130101)
G06F 9/30043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684909 August et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael A. August (San Diego, California);  Mamadou H. Diallo (Santee, California);  Dillon P. Glasser (New York City, New York);  Christopher T. Graves (San Diego, California);  Roger A. Hallman (San Diego, California);  Scott M. Slayback (San Diego, California)
ABSTRACT A system and method that automatically detects anomalies in a cloud service system on an ongoing basis and which can be used to trigger live migration of cloud services includes a cloud server system configured to provide a plurality of virtualized cloud services through processes running over a set of virtual machines hosted on the cloud server system, and a processor which receives data related to the operations of the virtual machines and determines whether any of the virtual machines are exhibiting anomalous behavior. The processor applies a Kalman Filter to make predictions on the future state and covariance of the virtual machines and then calculates the log likelihood of the predicted values. If the predicted values deemed to be very unlikely, then the processor signals that an anomaly has occurred.
FILED Tuesday, August 21, 2018
APPL NO 16/106740
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/45533 (20130101)
G06F 11/079 (20130101) Original (OR) Class
G06F 11/0709 (20130101)
G06F 11/0712 (20130101)
G06F 11/0751 (20130101)
G06F 11/0772 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685144 Hamilton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brett J. Hamilton (Heltonville, Indiana);  Andrew M. Howard (Bloomington, Indiana)
ABSTRACT Systems and methods for detecting counterfeit integrated circuits are provided. One exemplary embodiment of a method can include: providing an integrated circuit for testing; and characterizing capacitive and inductive loading of the integrated circuit power for a specified frequency range; wherein the characterizing step further comprises applying a low level alternating current to a power pin while measuring for capacitance characterization conditions created by the integrated circuit's internal capacitance and inductance responses, wherein by sweeping the alternating current signal across a specified frequency range one or more capacitance related device signature can be created and used to identify a component as originating from a trusted source or not. A system can include components and machine readable instructions for operating the components using exemplary methods. Exemplary embodiments can include automated systems that can also be used with the device signature on a production line or in a supply chain verification location.
FILED Monday, December 04, 2017
APPL NO 15/830989
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/26 (20130101)
G01R 31/2837 (20130101)
G01R 31/2839 (20130101)
G01R 31/2851 (20130101)

Electric Digital Data Processing
G06F 21/73 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685808 Lozano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
Air Force Office of Scientific Research (AFOSR)
Asian Office of Aerospace Research and Development (AOARD)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Paulo C. Lozano (Arlington, Massachusetts);  Steven Mark Arestie (Redondo Beach, California)
ABSTRACT An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip.
FILED Monday, July 15, 2019
APPL NO 16/511067
ART UNIT 2881 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/14 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 1/05 (20130101)
H01J 9/02 (20130101)
H01J 37/08 (20130101) Original (OR) Class
H01J 49/0445 (20130101)
H01J 2237/317 (20130101)
H01J 2237/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686041 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Connie H. Li (Alexandria, Virginia);  Glenn G. Jernigan (Waldorf, Maryland);  Berend T. Jonker (Waldorf, Maryland);  Ramasis Goswami (Alexandria, Virginia);  Carl S. Hellberg (Bethesda, Maryland)
ABSTRACT A 3C—SiC buffer layer on Si(001) comprising a porous buffer layer of 3C—SiC on a Si(001) substrate, wherein the porous buffer layer is produced through a solid state reaction, and wherein an amorphous carbon layer on the Si(001) substrate is deposited by magnetron sputtering of a C target at room temperature at a rate of 0.8 nm/min.
FILED Thursday, April 06, 2017
APPL NO 15/481138
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/324 (20130101)
H01L 21/02381 (20130101)
H01L 21/02433 (20130101)
H01L 21/02444 (20130101)
H01L 21/02447 (20130101)
H01L 21/02513 (20130101)
H01L 21/02527 (20130101)
H01L 21/02529 (20130101)
H01L 21/02587 (20130101)
H01L 21/02592 (20130101)
H01L 21/02612 (20130101)
H01L 21/02631 (20130101)
H01L 21/02658 (20130101)
H01L 21/30604 (20130101)
H01L 29/04 (20130101)
H01L 29/045 (20130101)
H01L 29/1608 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686116 Finkel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Peter Finkel (Baltimore, Maryland);  Margo Staruch (Alexandria, Virginia);  Fletcher Blackmon (Plymouth, Massachusetts);  Lynn Antonelli (Cranston, Rhode Island)
ABSTRACT Described herein is the use of large phase transformational strain in relaxor ferroelectric single crystals for broadband sound generation. The technique exploits the thermo-optical triggering and thus an opto-acoustic effect of ferroelectric phase transformation piezocrystals under mechanical bias conditions.
FILED Thursday, August 16, 2018
APPL NO 15/998482
ART UNIT 2653 — Videophones and Telephonic Communications
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/09 (20130101)
H01L 41/18 (20130101)
H01L 41/0536 (20130101)
H01L 41/1132 (20130101)
H01L 41/1875 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 2/009 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/44 (20130101)
H04R 7/04 (20130101)
H04R 17/00 (20130101)
H04R 23/002 (20130101)
H04R 23/02 (20130101)
H04R 23/008 (20130101)
H04R 31/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686227 Ergen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte.
FILED Monday, November 27, 2017
APPL NO 15/822563
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/4235 (20130101) Original (OR) Class
H01M 2300/0025 (20130101)
H01M 2300/0045 (20130101)
H01M 2300/0071 (20130101)
H01M 2300/0085 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686376 Guo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S) Ben Guo (West Hartford, Connecticut);  Suman Dwari (Vernon, Connecticut)
ABSTRACT A method of controlling a tunable passive component in a pulse width modulation controlled switched mode power supply (SMPS) having a power input and an output with tunable passive component power filter. The method includes operably connecting and supplying power relative to a circuit ground to a DC bus, converting a voltage on the DC bus to an output voltage by operating a first switching device and a second switching device at a selected frequency, and filtering the output voltage with a tunable output filter, the tunable output filter including a tunable passive component responsive to a control function circuit configured to automatically tune the tunable passive component value based on a voltage associated with operation of the power supply to maintain resonance of the tunable output filter at about the selected frequency.
FILED Monday, May 06, 2019
APPL NO 16/403944
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/14 (20130101)
H02M 3/158 (20130101) Original (OR) Class

Tuning Resonant Circuits; Selecting Resonant Circuits
H03J 1/0008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686463 Howard
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Matthew D. Howard (Beavercreek, Ohio)
ABSTRACT In accordance with various embodiments of the disclosed subject matter, a system, device, apparatus and method for calibrating a split bit digital readout to avoid misalignment of the least significant counter bit (i.e., the LSB of the M most significant bits) and most significant residual bit (i.e. the MSB of the N least significant bits). For example, various embodiments provide a field programmable gate array (FPGA), digital signal processing (DSP) function and the like configured to calibrate one or many split bit digital readouts such as may exist on a digital pixel sensor (DPS) or other device.
FILED Thursday, February 14, 2019
APPL NO 16/275488
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)
G06F 30/331 (20200101)

Coding; Decoding; Code Conversion in General
H03M 1/1004 (20130101)
H03M 1/1023 (20130101) Original (OR) Class
H03M 1/1052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686513 Learned et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Rachel E. Learned (Waltham, Massachusetts);  Paul D. Fiore (Chelmsford, Massachusetts)
ABSTRACT A receiver includes multi-user detection (MUD) functionality and a cognitive engine. The receiver may also be coupled to multiple antennas and have analog beamforming capability. The cognitive engine is operative for selecting a beam or beams associated with the multiple antennas to enable successful demodulation by the MUD. The receiver has application in multiple access channels and in other communication scenarios.
FILED Friday, May 25, 2018
APPL NO 15/989613
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/086 (20130101) Original (OR) Class

Secret Communication; Jamming of Communication
H04K 3/228 (20130101)
H04K 2203/32 (20130101)

Wireless Communication Networks
H04W 24/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686691 Hu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama);  San Diego State University (SDSU) Foundation (San Diego, California)
ASSIGNEE(S) The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama);  San Diego State University (SDSU) Foundation (San Diego, California)
INVENTOR(S) Fei Hu (Tuscaloosa, Alabama);  Qian Mao (Tuscaloosa, Alabama);  Lei Hu (Tuscaloosa, Alabama);  Sunil Kumar (San Diego, California)
ABSTRACT Disclosed and described herein are smart, high-speed UV communication protocols, inspired by the biological principles. The disclosed and described protocols use a ‘pipe’ routing topology to deliver large amount of data among the UVs equipped with multi-beam antennas. The disclosed and described embodiments include bio-inspired pipe routing and adaptive batch coding (ABC) based congestion control. In regard to bio-inspired pipe routing, a human's brain uses highly cooperative neuro cells to memorize everything. Inspired by neuro networks, a pipe architecture with high-throughput node-to-node data delivery is disclosed and described herein. The pipe routing uses multi-beam antennas to achieve parallel data transmission. In regard to ABC based congestion control, a new network coding called ABC is disclosed, which can minimize traffic congestion occurrences in the above pipe routing. The disclosed and described transport layer protocol includes both end-to-end reliability and congestion control.
FILED Thursday, July 12, 2018
APPL NO 16/033760
ART UNIT 2476 — Multiplex and VoIP
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
G06N 3/04 (20130101)

Transmission
H04B 7/0617 (20130101)
H04B 7/0695 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0009 (20130101)
H04L 1/0076 (20130101)
H04L 1/187 (20130101)
H04L 45/08 (20130101) Original (OR) Class
H04L 2001/0092 (20130101)

Wireless Communication Networks
H04W 4/40 (20180201)
H04W 40/02 (20130101)
H04W 84/06 (20130101)
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10687022 Rasheed et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
United States Marine Corps (USMC)
APPLICANT(S) AVIGILON FORTRESS CORPORATION (Vancouver, Canada)
ASSIGNEE(S) AVIGILON FORTRESS CORPORATION (Vancouver, Canada)
INVENTOR(S) Zeeshan Rasheed (Herndon, Virginia);  Dana Eubanks (Herndon, Virginia);  Weihong Yin (Great Falls, Virginia);  Zhong Zhang (Great Falls, Virginia);  Kyle Glowacki (Reston, Virginia);  Allison Beach (Leesburg, Virginia)
ABSTRACT Embodiments relate to systems, devices, and computer-implemented methods for performing automated visual surveillance by obtaining video camera coordinates determined using video data, video camera metadata, and/or digital elevation models, obtaining a surveillance rule associated with rule coordinates, identifying a video camera that is associated with video camera coordinates that include at least part of the rule coordinates, and transmitting the surveillance rule to a computing device associated with the video camera. The rule coordinates can be automatically determined based on received coordinates of an object. Additionally, the surveillance rule can be generated based on instructions from a user in a natural language syntax.
FILED Friday, December 04, 2015
APPL NO 14/959831
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00771 (20130101)
G06K 9/3241 (20130101)
G06K 9/6255 (20130101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101)
G06T 2207/30232 (20130101)
G06T 2219/2004 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 13/19671 (20130101)

Pictorial Communication, e.g Television
H04N 7/181 (20130101) Original (OR) Class
H04N 7/188 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10687126 Dupuis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Nicolas Dupuis (New York, New York);  Daniel M. Kuchta (Patterson, New York);  Benjamin G. Lee (Ridgefield, Connecticut);  Alexander Rylyakov (Staten Island, New York);  Clint L. Schow (Santa Barbara, California)
ABSTRACT Methods and systems for bias control in an optical switch fabric include monitoring optical power at outputs of a plurality of switch elements in an N×N switch fabric that has N inputs, N outputs, and M≥2 stages, each switch element having a respective unique radio frequency tone. A bias control of each of the plurality of switch elements is adjusted. It is determined whether the optical power at the outputs of each respective switch element after bias control adjustment conform more closely to a predetermined criterion relative to the monitored optical power at the outputs of the respective switch element prior to adjustment.
FILED Friday, June 08, 2018
APPL NO 16/003847
ART UNIT 2637 — Optical Communications
CURRENT CPC
Selecting
H04Q 11/0001 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10682738 Kasman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Elina Kasman (Naperville, Illinois);  Jonathan Montgomery (Naperville, Illinois)
ABSTRACT A device for polishing of a multi-surface workpiece is described. The device includes a base and a vertical motion platform that moves along two support rods, which carries a motor that drives a rotating shaft. The support rods extend from the base. A polishing tool is attached to the motor shaft. The workpiece being polished is placed on a linear motion stage during the polishing process.
FILED Friday, September 29, 2017
APPL NO 15/721568
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents
B24B 1/00 (20130101)
B24B 7/02 (20130101)
B24B 7/075 (20130101)
B24B 49/04 (20130101)
B24B 49/12 (20130101)
B24B 51/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683419 Helms et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Brett A. Helms (San Francisco, California);  Peter D. Frischmann (Berkeley, California);  Yoon Hwa (Emeryville, California);  Elton J. Cairns (Walnut Creek, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Brett A. Helms (San Francisco, California);  Peter D. Frischmann (Berkeley, California);  Yoon Hwa (Emeryville, California);  Elton J. Cairns (Walnut Creek, California)
ABSTRACT To address the need for multi-functional binders specifically tailored for sulfur cathodes π-stacked perylene bisimide (PBI) molecules are repurposed as redox-active supramolecular binders in sulfur cathodes for Li—S cells. In operando lithiation of PBI binders permanently reduces Li—S cell impedance enabling high-rate cycling, a critical step toward unlocking the full potential of Li—S batteries.
FILED Thursday, March 23, 2017
APPL NO 15/467099
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 471/06 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/04 (20130101)
C08K 3/06 (20130101)
C08K 9/04 (20130101)
C08K 9/04 (20130101)
C08K 2201/001 (20130101)

Compositions of Macromolecular Compounds
C08L 27/16 (20130101)
C08L 79/08 (20130101) Original (OR) Class
C08L 2203/20 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/136 (20130101)
H01M 4/364 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/661 (20130101)
H01M 10/052 (20130101)
H01M 10/0567 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683519 Davis et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Ryan Wesley Davis (San Jose, California);  Blake Simmons (San Francisco, California);  Mary Bao Tran-Gyamfi (Pleasanton, California);  Benjamin Chiau-Pin Wu (San Ramon, California)
ABSTRACT The present invention relates to methods of upgrading biomass to provide useful chemical intermediates, fuels, amino acids, nutrients, etc. In particular examples, the biomass is a by-product of ethanol production and is mainly used as high-protein feed. Described herein are methods for upgrading such biomass, such as by implementing pre-treatment conditions and by employing fermentation conditions including modified organisms.
FILED Thursday, March 02, 2017
APPL NO 15/447567
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/16 (20130101) Original (OR) Class
C12P 13/001 (20130101)

Enzymes
C12Y 101/01001 (20130101)
C12Y 101/01086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683579 Cooks et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Anyin Li (West Lafayette, Indiana);  Thalappil Pradeep (Madras, India);  Zane Baird (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions. In certain aspects, the invention provides methods that involve providing a metal and a solvent. The methods additionally involve applying voltage to the solvated metal to thereby produce solvent droplets including ions of the metal containing compound, and directing the solvent droplets including the metal ions to a target. In certain embodiments, once at the target, the metal ions can react directly or catalyze reactions.
FILED Friday, May 17, 2019
APPL NO 16/415531
ART UNIT 2881 — Optics
CURRENT CPC
Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 1/20 (20130101)
C25C 1/22 (20130101)
C25C 7/00 (20130101)
C25C 7/06 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 10/234 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683644 Kim et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Hyunho Kim (Cambridge, Massachusetts);  Sungwoo Yang (Cambridge, Massachusetts);  Sameer R. Rao (Colonie, New York);  Shankar Narayanan (Cambridge, Massachusetts);  Eugene A. Kapustin (Berkeley, California);  Hiroyasu Furukawa (Berkeley, California);  Ari S. Umans (Belmont, Massachusetts);  Omar M. Yaghi (Berkeley, California);  Evelyn N. Wang (Cambridge, Massachusetts)
ABSTRACT A water-harvesting system can operate with a material that can take up and release water with minimum energy requirements and powered by low-grade energy sources, such as sunlight, in order to potentially allow its deployment into households, especially those located in sunny regions. A water-harvesting method and system can include vapor adsorption using a porous metal-organic framework. In certain embodiments, the porous metal-organic framework can include metal-organic framework in ambient air with low relative humidity, typical of the levels found in most dry regions of the world.
FILED Friday, April 05, 2019
APPL NO 16/377146
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 5/0003 (20130101)
B01D 5/006 (20130101)
B01D 5/0015 (20130101)
B01D 15/36 (20130101)
B01D 53/261 (20130101)
B01D 2253/204 (20130101)
B01D 2257/80 (20130101)
B01D 2258/06 (20130101)
B01D 2259/80 (20130101)
B01D 2259/40098 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/20 (20130101)
B01J 20/103 (20130101)
B01J 20/226 (20130101)
B01J 20/324 (20130101)
B01J 20/3204 (20130101)
B01J 20/3236 (20130101)
B01J 20/3238 (20130101)
B01J 20/28047 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/288 (20130101)
C02F 2201/001 (20130101)
C02F 2201/32 (20130101)

Installations or Methods for Obtaining, Collecting, or Distributing Water
E03B 3/28 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 20/109 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684128 Sopori et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Bhushan Lal Sopori (Idledale, Colorado);  Michael Joseph Ulsh (Broomfield, Colorado);  Przemyslaw Rupnowski (Golden, Colorado);  Guido Bender (Arvada, Colorado);  Michael Mihaylov Penev (Golden, Colorado);  Jianlin Li (Knoxville, Tennessee);  David L. Wood, III (Knoxville, Tennessee);  Claus Daniel (Knoxville, Tennessee)
ABSTRACT Thermal methods and systems are described for the batch and/or continuous monitoring of films and/or membranes and/or electrodes produced in large-scale manufacturing lines. Some of the methods described include providing an energy input into a film, measuring a thermal response of the film, and correlating these to one or more physical properties and/or characteristics of the film.
FILED Tuesday, March 08, 2016
APPL NO 15/554551
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/085 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 9/00 (20130101)
G01N 15/088 (20130101)
G01N 25/005 (20130101)
G01N 25/18 (20130101)
G01N 2015/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684262 Steingart et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Daniel Artemis Steingart (Princeton, New Jersey);  Shoham Bhadra (North Brunswick, New Jersey);  Andrew Gaheem Hsieh (Berkeley, California);  Benjamin Hertzberg (Princeton, New Jersey);  Peter James Gjeltema (Stow, Massachusetts);  Clarence Worth Rowley, III (Princeton, New Jersey);  Alexandre S. R. Goy (Lawrenceville, New Jersey);  Jason Wolf Fleischer (Princeton, New Jersey)
ABSTRACT Systems and methods for prediction of state of charge (SOH), state of health (SOC) and other characteristics of batteries using acoustic signals, includes determining acoustic data at two or more states of charge and determining a reduced acoustic data set representative of the acoustic data at the two or more states of charge. The reduced acoustic data set includes time of flight (TOF) shift, total signal amplitude, or other data points related to the states of charge. Machine learning models use at least the reduced acoustic dataset in conjunction with non-acoustic data such as voltage and temperature for predicting the characteristics of any other independent battery.
FILED Wednesday, October 03, 2018
APPL NO 16/150655
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/07 (20130101)
G01N 29/043 (20130101)
G01N 29/46 (20130101)
G01N 29/4427 (20130101) Original (OR) Class
G01N 29/4436 (20130101)
G01N 2291/0231 (20130101)
G01N 2291/2698 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684287 Tang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) Chan Zuckerberg Biohub, Inc. (San Francisco, California);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Shaogeng Tang (Stanford, California);  Peter S. Kim (Stanford, California)
ABSTRACT Variants of human PD-1 comprising one or more of amino acid substitutions in residues corresponding to N74, T76 and A132 of SEQ ID NO:1 are described. Also described are structures, obtained using X-ray crystallography, of the human PD-1/PD-L2 complex and mutant PD-1 variants. The structures of human PD-1 described in the present disclosure are useful in drug discovery, including small-molecule drug discovery. Accordingly, methods of using the structures in drug discovery are also described.
FILED Monday, February 10, 2020
APPL NO 16/786409
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101) Original (OR) Class
G01N 2333/70521 (20130101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/30 (20190201)
G16C 20/64 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684308 Hirsch
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Gregory Hirsch (Pacifica, California)
ASSIGNEE(S)
INVENTOR(S) Gregory Hirsch (Pacifica, California)
ABSTRACT Techniques are disclosed for stabilizing soft specimen traditionally considered too fragile for APT instruments. These specimens include biological samples, polymers and other fragile materials. For this purpose, a protective structure is disclosed that surrounds the sides of the specimen by supporting walls while only exposing the very end or terminus of the specimen to the electrostatic field of the APT instrument. The protective structure may take the form of a nanoscale conical grinder which continually machines the specimen to regenerate the terminus of the specimen in-situ. Alternately, the protective structure may take the form of a nanopipette in which the specimen is first frozen before undergoing field evaporation together with the tip of the nanopipette. Heretofore only routinely possible for rigid and hard materials, the design thus extends APT analysis to produce three-dimensional atomic-scale maps of soft specimens.
FILED Thursday, December 06, 2018
APPL NO 16/212494
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/20 (20130101) Original (OR) Class
G01Q 60/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684957 Lebeane et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Michael W. Lebeane (Austin, Texas);  Seunghee Shin (Raleigh, North Carolina)
ABSTRACT An apparatus and method performs neighborhood-aware virtual to physical address translations. A coalescing opportunity for a first virtual address is determined, based on completing a memory access corresponding to a page walk for a second virtual address. Metadata corresponding to the first virtual address is provided to a page table walk buffer based on the coalescing opportunity and a page walk for the first virtual address is performed based on the metadata corresponding to the first virtual address.
FILED Thursday, August 23, 2018
APPL NO 16/110062
ART UNIT 2139 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/10 (20130101) Original (OR) Class
G06F 2212/65 (20130101)
G06F 2212/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684958 Nair et al.
FUNDED BY
Department of Energy (DOE)
Office of Scientific and Technical Information (OSTI)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Ravi Nair (Briarcliff Manor, New York);  Charles R. Johns (Austin, Texas)
ABSTRACT An approach is disclosed that locates a named data element by a local node. A name corresponding to the named data element is received, the named data element exists in a Coordination Namespace allocated in a memory area that is distributed amongst a set of nodes that include the local node and remote nodes. A predicted node identifier is received and then the named data element is requested from the predicted node based on the predicted node identifier.
FILED Monday, December 10, 2018
APPL NO 16/215244
ART UNIT 2132 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/1018 (20130101) Original (OR) Class
G06F 2212/657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685118 Prowell et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Stacy J. Prowell (Oak Ridge, Tennessee);  Jeffrey A. Nichols (Oak Ridge, Tennessee);  Jarilyn M. Hernandez Jimenez (Oak Ridge, Tennessee)
ABSTRACT A system and method (referred to as the system) detects malware, viruses, and/or malicious activity by generating a direct current source power consumption profile by causing a monitored device to execute a fully automated recurrent software operation. The system receives by an automated detection system, the direct current source power consumption profile generated by an intelligent power sensor and generates by a detection engine, a power security profile that identifies suspicious code by profiling direct current consumed by monitored type devices. The system executes a detection engine remote from the monitored device that identifies an infected device.
FILED Tuesday, May 15, 2018
APPL NO 15/980045
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 1/28 (20130101)
G06F 21/552 (20130101)
G06F 21/554 (20130101)
G06F 21/566 (20130101)
G06F 21/567 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685752 Liszkai
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S) NUSCALE POWER, LLC (Corvallis, Oregon)
INVENTOR(S) Tamas Liszkai (Corvallis, Oregon)
ABSTRACT A steam generation system may include a plurality of heat transfer tubes configured to circulate a secondary coolant of the steam generation system. The steam generation system may be thermally coupled to a reactor vessel, and the reactor vessel may be configured to house a primary coolant. Heat generated from within the reactor vessel may be transferred from the primary coolant to the secondary coolant. The steam generation system may further include an inclined tube sheet fluidly coupled to the plurality of heat transfer tubes. The inclined tube sheet may be attached to a wall of the reactor vessel in a non-horizontal orientation.
FILED Tuesday, February 10, 2015
APPL NO 14/618701
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 5/00 (20130101)

Nuclear Reactors
G21C 1/32 (20130101)
G21C 1/322 (20130101)
G21C 13/04 (20130101)
G21C 13/036 (20130101)
G21C 15/257 (20130101) Original (OR) Class

Nuclear Power Plant
G21D 1/006 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685754 Lahoda et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) WESTINGHOUSE ELECTRIC COMPANY, LLC (Cranberry Township, Pennsylvania)
ASSIGNEE(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S) Edward J. Lahoda (Edgewood, Pennsylvania);  Sumit Ray (Columbia, South Carolina)
ABSTRACT An improved testing and data gathering method is described herein with reference to testing a new fuel, as an exemplary component to be tested for licensure purposes. The method includes generally: generating models for the new system; making samples and getting them accepted for a reactor; and testing the samples in a test or commercial reactor until the exposure time is reached for the expected cycle length of the fuel at final use. The method is preferably done concurrent to submitting a license application for commercial use of the new component to the relevant government body to expedite license testing review.
FILED Tuesday, March 07, 2017
APPL NO 15/451643
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101)

Nuclear Reactors
G21C 17/00 (20130101)

Nuclear Power Plant
G21D 3/001 (20130101) Original (OR) Class
G21D 3/04 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685757 Katalenich et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jeffrey A. Katalenich (Richland, Washington);  Bruce D. Reid (Pasco, Washington);  Robert O. Gates (Kennewick, Washington);  Andrew W. Prichard (Pasco, Washington);  Bruce E. Schmitt (Kennewick, Washington);  Jim Livingston (Vienna, Virginia)
ABSTRACT Reactor target assemblies are provided that can include a housing defining a perimeter of at least one volume and Np or Am spheres within the one volume. Reactor assemblies are provided that can include a reactor vessel and a bundle of target assemblies within the reactor vessel, at least one of the target assemblies comprising a housing defining a volume with Np or Am spheres being within the volume. Irradiation methods are also provided that can include irradiating Np or Am spheres within a nuclear reactor, then removing the irradiated spheres from the reactor and treating the irradiated spheres.
FILED Friday, March 31, 2017
APPL NO 15/476870
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 3/28 (20130101)
G21C 3/58 (20130101)

Conversion of Chemical Elements; Radioactive Sources
G21G 1/001 (20130101)
G21G 1/02 (20130101) Original (OR) Class
G21G 2001/0094 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 6/00 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685758 Frye et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Clint Frye (Livermore, California);  Roger A. Henderson (Brentwood, California);  John Winter Murphy (Mountain House, California);  Rebecca J. Nikolic (Oakland, California);  Dongxia Qu (Livermore, California);  Qinghui Shao (Fremont, California);  Mark A. Stoyer (Livermore, California);  Lars Voss (Livermore, California)
ABSTRACT According to one embodiment, a product includes an array of three dimensional structures, a cavity region between each of the three dimensional structures, and a first material in contact with at least one surface of each of the three dimensional structures. In addition, each of the three dimensional structures includes a semiconductor material, where at least one dimension of each of the three dimensional structures is in a range of about 0.5 microns to about 10 microns. Moreover, the first material is configured to provide high energy particle and/or ray emissions.
FILED Friday, April 21, 2017
APPL NO 15/494219
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation
G21H 1/00 (20130101)
G21H 1/04 (20130101)
G21H 1/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685843 Youtsey et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) MICROLINK DEVICES, INC. (Niles, Illinois)
ASSIGNEE(S) MICROLINK DEVICES, INC. (Niles, Illinois)
INVENTOR(S) Christopher Youtsey (Libertyville, Illinois);  Robert McCarthy (Chicago, Illinois)
ABSTRACT Methods and systems for etching a substrate using photoenhanced wet etching techniques are described. At least one light emitting diode source is used to create a high intensity of ultraviolet light at the surface of the substrate or at one or more layers formed on the substrate. Etching rates in GaN substrates and GaN layers are improved by an order of magnitude over conventional systems. Systems and methods for forming a device structure free of a substrate are described. The device structure is grown or applied over a release layer on a substrate. The device structure is exposed to photoenhanced wet etch environments to vertically and laterally etch the release layer to separate the device structure from the substrate.
FILED Tuesday, July 24, 2018
APPL NO 16/044448
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/78 (20130101)
H01L 21/0254 (20130101)
H01L 21/02389 (20130101)
H01L 21/02458 (20130101)
H01L 21/02664 (20130101)
H01L 21/7813 (20130101)
H01L 21/30612 (20130101) Original (OR) Class
H01L 21/30635 (20130101)
H01L 21/67075 (20130101)
H01L 21/67086 (20130101)
H01L 29/2003 (20130101)
H01L 31/02363 (20130101)
H01L 33/22 (20130101)
H01L 33/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686110 Melsert et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama)
ASSIGNEE(S) Southern Research Institute (Birmingham, Alabama)
INVENTOR(S) Ryan Melsert (Reno, Nevada);  Jay Renew (Kennesaw, Georgia)
ABSTRACT Disclosed herein is a method and apparatus that uses a brine from a well that is used to both generate electricity and recover valuable minerals present in the brine. The method and apparatus uses a hydrophobic membrane to separate water vapor from the brine to concentrate the brine that is then used to recover the minerals.
FILED Thursday, May 17, 2018
APPL NO 15/982374
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/12 (20130101)
B01D 21/00 (20130101)
B01D 61/58 (20130101)
B01D 61/362 (20130101)
B01D 61/366 (20130101)
B01D 69/02 (20130101)
B01D 71/02 (20130101)
B01D 71/06 (20130101)
B01D 2325/38 (20130101)

Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 15/00 (20130101)
C01D 15/08 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 5/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/52 (20130101)
C02F 1/281 (20130101)
C02F 1/448 (20130101)
C02F 2101/10 (20130101)
C02F 2103/34 (20130101)
C02F 2303/10 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/00 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/133 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686183 Masarapu et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
U.S. State Government
State of California
California Energy Commission (CEC)
APPLICANT(S) Zenlabs Energy, Inc. (Newark, California)
ASSIGNEE(S) Zenlabs Energy, Inc. (Fremont, California)
INVENTOR(S) Charan Masarapu (Fremont, California);  Yogesh Kumar Anguchamy (Newark, California);  Yongbong Han (San Francisco, California);  Haixia Deng (Fremont, California);  Sujeet Kumar (Newark, California);  Herman A. Lopez (Sunnyvale, California)
ABSTRACT Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge.
FILED Tuesday, August 29, 2017
APPL NO 15/689261
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/24 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/0217 (20130101)
H01M 4/131 (20130101) Original (OR) Class
H01M 4/134 (20130101)
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 10/052 (20130101)
H01M 10/446 (20130101)
H01M 10/0562 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686195 Yang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Peidong Yang (Kensington, California);  Vojislav Stamenkovic (Naperville, Illinois);  Gabor A. Somorjai (Berkeley, California);  Nenad Markovic (Hinsdale, Illinois);  Chen Chen (Beijing, China PRC);  Yijin Kang (Naperville, Illinois);  Nigel H. Becknell (Berkeley, California)
ABSTRACT Described herein are bimetallic nanoframes and methods for producing bimetallic nanoframes. A method may include providing a solution including a plurality of nanoparticles dispersed in a solvent, and exposing the solution to oxygen to convert the plurality of nanoparticles into a plurality of nanoframes.
FILED Wednesday, February 18, 2015
APPL NO 14/625443
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof
B82B 3/0033 (20130101)

Alloys
C22C 1/02 (20130101)
C22C 5/04 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/921 (20130101) Original (OR) Class
H01M 4/928 (20130101)
H01M 4/8657 (20130101)
H01M 4/8889 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686224 Angell et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) C. Austen Angell (Mesa, Arizona);  Leigang Xue (Austin, Texas)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) C. Austen Angell (Mesa, Arizona);  Leigang Xue (Austin, Texas)
ABSTRACT A battery includes an anode chamber configured to contain an anolyte and including an anode, a cathode chamber configured to contain a catholyte including a cathode, and a separator between the anode chamber and the cathode chamber. The anode includes sodium, and the cathode includes aluminum. The battery is configured to be operated above a melting point of the anolyte and the catholyte, such that the anolyte is a molten anolyte and the catholyte is a molten catholyte.
FILED Wednesday, April 18, 2018
APPL NO 15/956630
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/1646 (20130101)
H01M 2/1686 (20130101)
H01M 4/381 (20130101)
H01M 10/399 (20130101) Original (OR) Class
H01M 2300/0057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686227 Ergen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte.
FILED Monday, November 27, 2017
APPL NO 15/822563
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/4235 (20130101) Original (OR) Class
H01M 2300/0025 (20130101)
H01M 2300/0045 (20130101)
H01M 2300/0071 (20130101)
H01M 2300/0085 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686234 Zarkesh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Ryan A. Zarkesh (Livermore, California);  Forrest S. Gittleson (Livermore, California)
ABSTRACT An ionic liquid comprising a cationic chemical species and an anionic chemical species. The cationic chemical species comprising a nitrogen containing moiety and a partially fluorinated alkyl chain moiety, wherein the partially fluorinated alkyl chain moiety is bonded to a nitrogen atom of the nitrogen containing moiety. The ionic liquid can be used as an electrolyte, as an additive to an organic solvent, as a lubricant, as a hydrophobic coating, as a treatment for fluorinated pollutants, as an electrolyte for sensor applications, as a stabilizing additive for existing battery electrolytes, and as an emulsifier.
FILED Tuesday, August 01, 2017
APPL NO 15/666276
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/90 (20130101)
H01M 4/382 (20130101)
H01M 12/08 (20130101) Original (OR) Class
H01M 2300/0045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686321 Ravi et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S) Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S) Nikhil Ravi (Mountain View, California);  Anahita MirTabatabaei (San Francisco, California);  Reinhardt Klein (Mountain View, California);  Ashish Krupadanam (Cupertino, California);  John F. Christensen (Elk Grove, California);  Aleksandar Kojic (Sunnyvale, California);  Sarah Stewart (San Francisco, California);  Sun Ung Kim (Fremont, California);  Christina Johnston (Mountain View, California)
ABSTRACT A method of managing a battery system, the battery system including at least one battery cell, at least one sensor configured to measure at least one characteristic of the battery cell, and a battery management system including a microprocessor and a memory, the method comprising receiving by the battery management system, from the at least one sensor at least one measured characteristic of the battery cell at a first time and at least one measured characteristic of the battery cell at a second time. The battery management system estimating, at least one state of the battery cell by applying a physics-based battery model, the physics based battery model being based on differential algebraic equations; and regulating by the battery management system, at least one of charging or discharging of the battery cell based on the at least one estimated state.
FILED Friday, January 29, 2016
APPL NO 15/010873
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/44 (20130101)
H01M 10/48 (20130101)
H01M 10/052 (20130101)
H01M 10/425 (20130101)
H01M 10/4257 (20130101)
H01M 2010/4271 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/0021 (20130101)
H02J 7/0063 (20130101) Original (OR) Class
H02J 7/0072 (20130101)
H02J 2007/0067 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686643 Beukema et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Troy James Beukema (Briarcliff Manor, New York);  Martin Cochet (White Plains, New York);  John Francis Bulzacchelli (Somers, New York)
ABSTRACT A device can comprise a peaked integrator circuit that generates an output signal from a continuous time signal based on a sub rate clock timing cycle. The device can further comprise a track and hold circuit coupled to the output of the peaked integrator that generates a held discrete time signal from the output of the peaked integrator based on a second sub rate clock timing cycle that is offset in time from the sub rate clock timing cycle by a single time unit interval. The device can further comprise an integrator circuit coupled to an output of the track and hold circuit that integrates the held discrete time signal, based on the second sub rate clock timing cycle that is offset in time from the sub rate clock timing cycle by a single time unit interval.
FILED Monday, March 04, 2019
APPL NO 16/291322
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/0002 (20130101)
H04L 27/2649 (20130101)
H04L 27/3881 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686806 Abbaszadeh et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Masoud Abbaszadeh (Clifton Park, New York);  Lalit Keshav Mestha (North Colonie, New York);  Weizhong Yan (Clifton Park, New York)
ABSTRACT According to some embodiments, a plurality of monitoring nodes may each generate a series of current monitoring node values over time that represent a current operation of the industrial asset. A node classifier computer, coupled to the plurality of monitoring nodes, may receive the series of current monitoring node values and generate a set of current feature vectors. The node classifier computer may also access at least one multi-class classifier model having at least one decision boundary. The at least one multi-class classifier model may be executed and the system may transmit a classification result based on the set of current feature vectors and the at least one decision boundary. The classification result may indicate, for example, whether a monitoring node status is normal, attacked, or faulty.
FILED Monday, August 21, 2017
APPL NO 15/681827
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10687412 Simpson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Sean Simpson (Rio Rancho, New Mexico);  Owen Johns (Albuquerque, New Mexico);  Charles E. Rose (Severance, Colorado);  Azer Yalin (Fort Collins, Colorado);  Ciprian Dumitrache (Paris, France)
ABSTRACT A photonic-crystal-fiber-delivered laser-triggered high-voltage gas switch can deliver a peak irradiance of greater than 5.1×1011 W/cm2 to the AK gap for a laser having a wavelength of 1064 nm. The switch is capable of operating at pressures up to 2200 psi; voltages across the gap of greater than 200 kV; operation at less than 70% self-break voltage; shot-to-shot jitter of less than 3 ns; AK gap distances of 3 mm or smaller; and triggering via a fiber-delivered laser pulse energy of as low as 500 μJ.
FILED Monday, September 09, 2019
APPL NO 16/564685
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/02328 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10682442 Puleo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) David Puleo (Lexington, Kentucky);  Todd Milbrandt (Lexington, Kentucky);  James Zach Hilt (Lexington, Kentucky);  Paul Fisher (Lexington, Kentucky);  Vishwas Talwalkar (Lexington, Kentucky)
ABSTRACT The present invention relates to an injectable system combining a hydrogel, a bioceramic and a degradable matrix that provides for sustained drug delivery and structural support to recovering tissue, such as bone and the periodontium.
FILED Friday, April 03, 2015
APPL NO 14/678479
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 31/65 (20130101)
A61K 31/366 (20130101)
A61K 31/663 (20130101)
A61K 47/36 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/12 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101) Original (OR) Class
A61L 2300/602 (20130101)
A61L 2400/06 (20130101)
A61L 2430/02 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682622 Gaillard et al.
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Office of Experimental Program to Stimulate Competitive Research (EPSCOR)
APPLICANT(S) William Randall Gaillard (Madison, Alabama);  John D. Williams (Decatur, Alabama)
ASSIGNEE(S) Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama)
INVENTOR(S) William Randall Gaillard (Madison, Alabama);  John D. Williams (Decatur, Alabama)
ABSTRACT A micro-fluidic reactor may comprise a photosensitive glass substrate with a plurality of features produced by etching. The features may include micro-channels, micro-lenses, and slots for receiving optical fibers. During operation of the micro-fluidic reactor, the optical fibers may transmit optical signals for measuring characteristics of fluid reagents and reactions taking place. The micro-lenses may focus optical signals from the optical fibers to create an approximately collimated optical path for the optical signals, reducing optical spread and enhancing fiber-to-fiber optical power coupling.
FILED Wednesday, May 03, 2017
APPL NO 15/585745
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0093 (20130101) Original (OR) Class
B01J 2219/0097 (20130101)
B01J 2219/00801 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/18 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/06 (20130101)
G02B 6/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683455 Cholli et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Polnox Corporation (Lowell, Massachusetts)
ASSIGNEE(S) Polnox Corporation (Lowell, Massachusetts)
INVENTOR(S) Ashok L. Cholli (Lowell, Massachusetts);  Vijayendra Kumar (Lowell, Massachusetts)
ABSTRACT Disclosed are compounds represented by structural formula methods of producing compounds represented by structural formula, and their use in inhibiting oxidation in an oxidizable material.
FILED Tuesday, April 02, 2019
APPL NO 16/372594
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 209/60 (20130101)
C07C 213/00 (20130101)
C07C 213/00 (20130101)
C07C 213/02 (20130101)
C07C 217/28 (20130101)
C07C 217/28 (20130101)
C07C 217/42 (20130101)
C07C 231/02 (20130101)
C07C 231/02 (20130101)
C07C 231/04 (20130101)
C07C 235/34 (20130101)
C07C 235/34 (20130101)
C07C 235/38 (20130101)
C07C 235/38 (20130101)

Heterocyclic Compounds
C07D 251/30 (20130101)
C07D 251/34 (20130101)
C07D 251/46 (20130101)
C07D 251/52 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/20 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 15/24 (20130101) Original (OR) Class

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 133/16 (20130101)
C10M 2215/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683537 Kermekchiev et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) DNA Polymerase Technology, Inc. (St. Louis, Missouri)
ASSIGNEE(S) DNA Polymerase Technology, Inc. (St. Louis, Missouri)
INVENTOR(S) Milko B. Kermekchiev (St. Louis, Missouri);  Zhian Zhang (Ballwin, Missouri)
ABSTRACT Provided herein are mutant polymerase enzymes resistant to inhibitors encountered in Polymerase Chain Reactions (PCR). Also provided are nucleic acids or constructs encoding isolated polypeptides having polymerase activity. Also provided are kits useful for PCR containing isolated polypeptides having polymerase activity or isolated nucleic acids encoding such.
FILED Wednesday, October 16, 2013
APPL NO 14/055796
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/686 (20130101)
C12Q 2521/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684240 Sorgenfrei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Trustees Of Columbia University In the City of New York (New York, New York)
ASSIGNEE(S) The Trustees Of Columbia University In the City of New York (New York, New York)
INVENTOR(S) Sebastian Sorgenfrei (Portland, Oregon);  Kenneth L. Shepard (Ossining, New York);  Chien-Yang Chiu (Goleta, California);  Colin Nuckolls (New York, New York);  Steven Warren (White Plains, New York)
ABSTRACT A method for single-molecule detection is provided and uses a carbon nanotube having a probe entity attached thereto to define a first state of the carbon nanotube. The carbon nanotube is introduced to a target entity to define a second state of the carbon nanotube. The electrical conductance of the carbon nanotube in the first and second states is compared to detect the presence of a biomolecular entity. A system for single-molecule detection including a carbon nanotube is also provided.
FILED Thursday, December 28, 2017
APPL NO 15/857010
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/116 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2563/157 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/041 (20130101) Original (OR) Class
G01N 27/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684249 Gunasekaran et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Sundaram Gunasekaran (Madison, Wisconsin);  Woo-Jin Chang (Whitefish Bay, Wisconsin);  Jiang Yang (New York, New York);  Rajesh Seenivasan (Madison, Wisconsin)
ABSTRACT A device for measuring pH levels and contaminant concentration includes an electrode assembly that is electrically coupled to a control unit. The electrode assembly includes a first contact electrically coupled to a reference electrode, a second contact electrically coupled to a working electrode, and a third contact electrically coupled to a counter electrode. The working electrode may be modified to include a cysteine functionalized graphene oxide with polypyrrole nanocomposite. In operation, the control unit may apply a complex signal to the working electrode via the second contact in order to adhere and subsequently strip contaminant ions from the fluid sample to the working electrode. During this process, a current may be measured across the working electrode and the counter electrode to measure contaminant ion concentration. The pH of the fluid sample may also be determined by a current measured across the reference electrode and the counter electrode. In some examples, the pH may be used to calibrate the measured levels of the contaminant ions.
FILED Thursday, December 03, 2015
APPL NO 15/529211
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/42 (20130101)
G01N 27/301 (20130101)
G01N 27/302 (20130101)
G01N 27/308 (20130101)
G01N 27/333 (20130101)
G01N 27/4115 (20130101) Original (OR) Class
G01N 27/4148 (20130101)
G01N 27/4167 (20130101)
G01N 33/1813 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684262 Steingart et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Daniel Artemis Steingart (Princeton, New Jersey);  Shoham Bhadra (North Brunswick, New Jersey);  Andrew Gaheem Hsieh (Berkeley, California);  Benjamin Hertzberg (Princeton, New Jersey);  Peter James Gjeltema (Stow, Massachusetts);  Clarence Worth Rowley, III (Princeton, New Jersey);  Alexandre S. R. Goy (Lawrenceville, New Jersey);  Jason Wolf Fleischer (Princeton, New Jersey)
ABSTRACT Systems and methods for prediction of state of charge (SOH), state of health (SOC) and other characteristics of batteries using acoustic signals, includes determining acoustic data at two or more states of charge and determining a reduced acoustic data set representative of the acoustic data at the two or more states of charge. The reduced acoustic data set includes time of flight (TOF) shift, total signal amplitude, or other data points related to the states of charge. Machine learning models use at least the reduced acoustic dataset in conjunction with non-acoustic data such as voltage and temperature for predicting the characteristics of any other independent battery.
FILED Wednesday, October 03, 2018
APPL NO 16/150655
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/07 (20130101)
G01N 29/043 (20130101)
G01N 29/46 (20130101)
G01N 29/4427 (20130101) Original (OR) Class
G01N 29/4436 (20130101)
G01N 2291/0231 (20130101)
G01N 2291/2698 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684266 Swager et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Sophie Liu (Cambridge, Massachusetts);  Graham Thomas Sazama (Chestnut Hill, Massachusetts)
ABSTRACT A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region can include a complex, and the complex can include a carbon nanotube that is functionalized by a porphyrin.
FILED Saturday, April 02, 2016
APPL NO 15/089526
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/127 (20130101)
G01N 33/12 (20130101) Original (OR) Class
G01N 33/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684267 Peterman et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) OndaVia, Inc. (Hayward, California)
ASSIGNEE(S) OndaVia, Inc. (Hayward, California)
INVENTOR(S) Mark Charles Peterman (Fremont, California);  Merwan Benhabib (San Francisco, California);  Carlos Atico Ariza (Hayward, California);  Samuel Louis Kleinman (Oakland, California)
ABSTRACT A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
FILED Wednesday, September 04, 2019
APPL NO 16/560579
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)
G01N 33/18 (20130101) Original (OR) Class
G01N 33/182 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684417 Backman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  AMERICAN BIOOPTICS, LLC (Chicago, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois);  AMERICAN BIOOPTICS, LLC (Chicago, Illinois)
INVENTOR(S) Vadim Backman (Chicago, Illinois);  Jeremy D. Rogers (Madison, Wisconsin);  Nikhil N. Mutyal (Evanston, Illinois);  Bradley Gould (Evanston, Illinois);  Andrew J. Radosevich (Evanston, Illinois);  The Quyen Nguyen (Evanston, Illinois)
ABSTRACT Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.
FILED Thursday, February 01, 2018
APPL NO 15/886431
ART UNIT 2874 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)
A61B 5/0084 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/474 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/262 (20130101) Original (OR) Class
G02B 6/3807 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685114 Scaife et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Walter N. Scaife (Gainesville, Florida);  Patrick G. Traynor (Gainesville, Florida);  Henry Carter (Bryn Mawr, Pennsylvania);  Kevin Butler (Gainesville, Florida)
ABSTRACT Techniques and systems are described for detecting malware's bulk transformation of a user's data before the malware is able to complete the data transformation. Included are methods and systems for enabling malware detection by monitoring the file operations of a computer application or process for particular kinds of suspicious data transformation indicators. Indicators include primary indicators, such as file-type signature changes, notable changes in file data entropy, and out-of-range similarity measurements between the read and write versions of file data, as well as secondary indicators, such as a large number of file deletions and a large reduction in the number of file-types written versus read by a process over time. When indicators are triggered by a process, an adjustment to the process' malware score is made; in the event that the process' malware score reaches a malware detection threshold, the process is marked as malware and appropriate actions are taken.
FILED Friday, September 23, 2016
APPL NO 15/759014
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/565 (20130101)
G06F 21/566 (20130101) Original (OR) Class
G06F 21/6218 (20130101)
G06F 2221/034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685142 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) XiaoFeng Wang (Bloomington, Indiana);  Kan Yuan (Bloomington, Indiana);  Xiaoyong Zhou (Sunnyvale, California);  Muhammad Naveed (Urbana, Illinois);  Soteris Demetriou (Urbana, Illinois);  Carl Gunter (Urbana, Illinois)
ABSTRACT The present disclosure provides a security enhanced channel control system useable on a wireless device comprising a policy module including at least one processor and memory, the policy module configured to store, in the memory, one or more security policies and apply a compliance check to a first system layer and a second system layer; and a first policy base stored in the memory of the policy module, the first policy base being associated with a mandatory access control (“MAC”) base and defining one more security polices for access to a plurality of channels associated with the first and second system layers. The policy module cooperates with the first policy base to establish one or more access control rules that are applied to at least one of the plurality of channels to preclude an unauthorized application from accessing at least one of the channels.
FILED Tuesday, February 02, 2016
APPL NO 15/547402
ART UNIT 2493 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6281 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685181 Birnbaum et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Lawrence A. Birnbaum (Evanston, Illinois);  Shawn O'Banion (Chicago, Illinois)
ABSTRACT Disclosed herein are systems, methods and computer readable storage media for determining tags or labels from natural language expressions expressing a preference or choice, determining attributes from natural language expressions and other data, and predicting preferences from natural language expressions and other data.
FILED Thursday, March 06, 2014
APPL NO 14/199079
ART UNIT 2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 40/279 (20200101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/02 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 15/1822 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685781 Liu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Kai Liu (Davis, California);  Julius De Rojas (Davis, California);  Dustin A. Gilbert (Germantown, Maryland)
ABSTRACT A method for synthesis of high anisotropy L10 FeNi (tetrataenite) thin films is provided that combines physical vapor deposition via atomic layer sputtering and rapid thermal annealing with extreme heating and cooling speeds. The methods can induce L10-ordering in FeNi thin films. The process uses a base composite film of a support substrate, a seed layer, a multilayer thin film of FeNi with alternating single atomic layers of Fe and Ni that mimics the atomic plane of the final L10 FeNi alloy, and a capping layer. The Fe and Ni bilayers are grown on top of a Si substrate with a thermally oxidized SiO2 seed layer to mechanically strain the sample during rapid thermal annealing.
FILED Thursday, November 29, 2018
APPL NO 16/203933
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/015 (20130101)
B32B 2307/208 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/165 (20130101)
C23C 14/5806 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/14716 (20130101)
H01F 41/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686227 Ergen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
APPLICANT(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Onur Ergen (Berkeley, California);  Alexander K. Zettl (Kensington, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte.
FILED Monday, November 27, 2017
APPL NO 15/822563
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/4235 (20130101) Original (OR) Class
H01M 2300/0025 (20130101)
H01M 2300/0045 (20130101)
H01M 2300/0071 (20130101)
H01M 2300/0085 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10687329 Nosratinia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Aria Nosratinia (Plano, Texas);  Mohamed Fadel Shady (Richardson, Texas)
ABSTRACT Various examples are provided for coherence diversity. In one example, a method includes receiving a product signal transmitted over a plurality of subcarriers, the product signal including a product superposition of a first baseband signal and a second baseband signal; estimating equivalent channel responses for the plurality of subcarriers based upon the pilot symbol in the number of time slots of the plurality of subcarriers; and decoding the second encoded message based at least in part upon the first baseband signal and the equivalent channel responses. The first baseband signal can include a pilot symbol in a number of time slots of at least a portion of the plurality of subcarriers and a first encoded message in a remaining number of time slots of the plurality of subcarriers, and the second baseband signal can include a second encoded message.
FILED Monday, January 08, 2018
APPL NO 15/864769
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/12 (20130101)
H04B 7/0491 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/0023 (20130101)
H04L 5/0035 (20130101)
H04L 5/0048 (20130101)
H04L 25/021 (20130101)
H04L 25/0222 (20130101)
H04L 25/0224 (20130101)

Wireless Communication Networks
H04W 72/044 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10681923 Tang et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Washington State University (Pullman, Washington)
ASSIGNEE(S) Washington State University (Pullman, Washington)
INVENTOR(S) Juming Tang (Pullman, Washington);  Fang Liu (Pullman, Washington)
ABSTRACT An improved transport carrier for use in a fluid filled microwave sterilization or pasteurization system includes patterned electrically conductive layers or carriers which extend over or under items to be sterilized or pasteurized and occlude 1 to 30% of the area in the direct path of microwave emissions to the items. When the patterned electrically conductive layers or cages are present, heating of the items to be sterilized or pasteurized is substantially more uniform compared to when there is nothing occluding or otherwise interrupting the direct pathway from the microwave emitters to the items. Enhanced automation is achieved for sterilization or pasteurization systems by configuring the preheating and cooling sections as loading and unloading sections. Furthermore, superior fluid temperature control between the loading, heating, and unloading sections is achieved using double gates or dividers between sections.
FILED Wednesday, February 28, 2018
APPL NO 15/907722
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 3/001 (20130101)
A23L 3/01 (20130101) Original (OR) Class
A23L 3/04 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/12 (20130101)
A61L 2/26 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/80 (20130101)
H05B 6/782 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10682314 Gourapura et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Renukaradhya Gourapura (Wooster, Ohio);  Santosh Dhakal (Wooster, Ohio);  Jagadish Hiremath (Wooster, Ohio);  Chang-Won Lee (Wooster, Ohio)
ABSTRACT Disclosed herein are methods and compositions for treating or preventing swine influenza in a subject.
FILED Thursday, May 26, 2016
APPL NO 15/575734
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5153 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 39/145 (20130101)
A61K 2039/57 (20130101)
A61K 2039/543 (20130101)
A61K 2039/544 (20130101)
A61K 2039/552 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 7/06 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16161 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683330 Joens et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Lynn A. Joens (Tucson, Arizona);  Bibiana Law (Tucson, Arizona);  Alexandra Armstrong (Tucson, Arizona)
ABSTRACT The present disclosure provides immunogenic compositions against Campylobacter and methods for using the immunogenic composition to generate an immune response against Campylobacter and/or reduce intestinal colonization by Campylobacter.
FILED Thursday, July 05, 2018
APPL NO 16/027575
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/105 (20130101)
A61K 2039/53 (20130101)
A61K 2039/522 (20130101)
A61K 2039/523 (20130101)

Peptides
C07K 14/205 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684249 Gunasekaran et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Sundaram Gunasekaran (Madison, Wisconsin);  Woo-Jin Chang (Whitefish Bay, Wisconsin);  Jiang Yang (New York, New York);  Rajesh Seenivasan (Madison, Wisconsin)
ABSTRACT A device for measuring pH levels and contaminant concentration includes an electrode assembly that is electrically coupled to a control unit. The electrode assembly includes a first contact electrically coupled to a reference electrode, a second contact electrically coupled to a working electrode, and a third contact electrically coupled to a counter electrode. The working electrode may be modified to include a cysteine functionalized graphene oxide with polypyrrole nanocomposite. In operation, the control unit may apply a complex signal to the working electrode via the second contact in order to adhere and subsequently strip contaminant ions from the fluid sample to the working electrode. During this process, a current may be measured across the working electrode and the counter electrode to measure contaminant ion concentration. The pH of the fluid sample may also be determined by a current measured across the reference electrode and the counter electrode. In some examples, the pH may be used to calibrate the measured levels of the contaminant ions.
FILED Thursday, December 03, 2015
APPL NO 15/529211
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/42 (20130101)
G01N 27/301 (20130101)
G01N 27/302 (20130101)
G01N 27/308 (20130101)
G01N 27/333 (20130101)
G01N 27/4115 (20130101) Original (OR) Class
G01N 27/4148 (20130101)
G01N 27/4167 (20130101)
G01N 33/1813 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP31863 NeSmith
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) D. Scott NeSmith (Molena, Georgia)
ABSTRACT The new variety ‘TH-1125’ ripens around early May in south Georgia. The fruit of the new variety ‘TH-1125’ are large, firm and have good flavor. The new variety ‘TH-1125’ is vigorous with an estimated chilling requirement of about 250 to 300 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
FILED Wednesday, January 16, 2019
APPL NO 16/350818
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/368 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 10682672 Bombaugh et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Scott R. Bombaugh (Burke, Virginia);  Thomas J. Foti (Annandale, Virginia);  David E. Loyd (Stafford, Virginia);  Sarvang D. Shah (Fairfax, Virginia)
ABSTRACT Embodiments of a system and method for sorting and delivering articles in a processing facility. Delivery endpoints are divided and grouped into stop groups. A first sorter sorts items according to stop group and outputs the items to trays. The output trays from the first sorter are loaded to a second sorter. The second sorter sorts items for each stop group into trays based on carrier route segments. A manifest is created that comprises a list of the items in a tray. A mobile computing device alerts a delivery carrier when there is an item that needs to be delivered.
FILED Wednesday, July 18, 2018
APPL NO 16/039241
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/00 (20130101)
B07C 3/005 (20130101) Original (OR) Class
B07C 3/14 (20130101)
B07C 2301/0041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685193 Ashaari et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Shahpour Ashaari (Bethesda, Maryland);  David C. Lin (Falls Church, Virginia);  Seth S. Vasa (Olney, Maryland);  Scott R. Bombaugh (Burke, Virginia);  Mario Andre Salisbury (Miami, Florida);  Thomas Jay Graham (Chantilly, Virginia);  Erich Joseph Petre (Gainesville, Virginia)
ABSTRACT Systems and methods of identifying wearable tags or other items within a facility. The location of the identifiable item can be calculated by the system and used to improve the efficiency of the facility or to dispatch emergency help or maintenance to the location of the badge.
FILED Thursday, April 18, 2019
APPL NO 16/387872
ART UNIT 2887 — Optics
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4183 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10099 (20130101) Original (OR) Class
G06K 7/10475 (20130101)
G06K 19/07758 (20130101)

Wireless Communication Networks
H04W 4/021 (20130101)
H04W 4/33 (20180201)
H04W 4/35 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10685317 Aryeetey et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Nii-Kwashie Aryeetey (Accokeek, Maryland);  Markes Lucius (Arlington, Virginia);  Matthew J. Mazzola (Washington, District of Columbia)
ABSTRACT Embodiments relate to systems, devices, and computer-implemented methods for tracking delivery items associated with a postal tracking product that includes a tracking bar code and a serial number. The tracking bar code can be attached to a delivery item and mailed. The delivery item can be processed by a delivery processing system, which can capture an image of the delivery item and the tracking bar code, and can extract a tracking number from the tracking bar code. The delivery processing system can report information on the location of the delivery item using the tracking number, and an indication of the location can be provided to a user that enters the serial number into a tracking interface.
FILED Wednesday, September 21, 2016
APPL NO 15/272166
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10722 (20130101)
G06K 19/06028 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10682393 Srinivasan
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Emory University (Atlanta, Georgia);  U.S. Government represented by the United States Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  The United States Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Shanthi Srinivasan (Atlanta, Georgia)
ABSTRACT The disclosure relates to therapeutic methods for regulating weight gain, metabolic syndrome, and insulin resistance. In certain embodiments, the disclosure relates to methods of treating or preventing obesity, metabolic syndrome, or insulin resistance by administering an effective amount of a pharmaceutical composition comprising one or more GDNF receptor agonists to a subject in need thereof.
FILED Tuesday, July 17, 2018
APPL NO 16/037268
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/185 (20130101) Original (OR) Class

Peptides
C07K 14/475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10683363 Weisbart et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Richard H. Weisbart (Sepulveda, California);  Robert N. Nishimura (Sepulveda, California)
ABSTRACT The invention provides a method for inhibiting an intracellular target in a cell with a bispecific antibody comprising contacting the cell with a bispecific antibody having a first Fv fragment with a cell-penetrating determinant and a second Fv fragment with an intracellular target-binding determinant under suitable conditions so that the first Fv fragment causes the bispecific antibody to enter the cell and the second Fv fragment binds the intracellular target in the cell and thereby inhibiting the intracellular target.
FILED Thursday, February 11, 2016
APPL NO 15/042106
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 16/30 (20130101) Original (OR) Class
C07K 16/32 (20130101)
C07K 16/42 (20130101)
C07K 16/44 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/77 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10682349 Bassaganya-Riera et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Landos Biopharma, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) LANDOS BIOPHARMA, INC. (Blacksburg, Virginia)
INVENTOR(S) Josep Bassaganya-Riera (Blacksburg, Virginia);  Adria Carbo Barrios (Blacksburg, Virginia);  Richard Gandour (Blacksburg, Virginia);  Julian D. Cooper (Blacksburg, Virginia);  Raquel Hontecillas (Blacksburg, Virginia)
ABSTRACT Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including infectious disease, autoimmune disease, diabetes, and a chronic inflammatory disease.
FILED Tuesday, October 15, 2019
APPL NO 16/653446
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/423 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)

Acyclic or Carbocyclic Compounds
C07C 65/40 (20130101)

Heterocyclic Compounds
C07D 213/69 (20130101)
C07D 213/79 (20130101)
C07D 307/60 (20130101)
C07D 307/68 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 403/14 (20130101)
C07D 413/12 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10684267 Peterman et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) OndaVia, Inc. (Hayward, California)
ASSIGNEE(S) OndaVia, Inc. (Hayward, California)
INVENTOR(S) Mark Charles Peterman (Fremont, California);  Merwan Benhabib (San Francisco, California);  Carlos Atico Ariza (Hayward, California);  Samuel Louis Kleinman (Oakland, California)
ABSTRACT A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
FILED Wednesday, September 04, 2019
APPL NO 16/560579
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)
G01N 33/18 (20130101) Original (OR) Class
G01N 33/182 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10682411 Monson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
ASSIGNEE(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
INVENTOR(S) Ellen K. Monson (Cincinnati, Ohio);  Xiaochen Wei (Fort Mitchell, Kentucky);  Ray Takigiku (Covington, Kentucky);  Charles A. Cruze, III (West Chester, Ohio);  Joseph W. Wyse (Nicholasville, Kentucky)
ABSTRACT Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers.
FILED Friday, November 02, 2018
APPL NO 16/179139
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/127 (20130101)
A61K 38/18 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101) Original (OR) Class
A61K 47/18 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10686183 Masarapu et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
U.S. State Government
State of California
California Energy Commission (CEC)
APPLICANT(S) Zenlabs Energy, Inc. (Newark, California)
ASSIGNEE(S) Zenlabs Energy, Inc. (Fremont, California)
INVENTOR(S) Charan Masarapu (Fremont, California);  Yogesh Kumar Anguchamy (Newark, California);  Yongbong Han (San Francisco, California);  Haixia Deng (Fremont, California);  Sujeet Kumar (Newark, California);  Herman A. Lopez (Sunnyvale, California)
ABSTRACT Improved high energy capacity designs for lithium ion batteries are described that take advantage of the properties of high specific capacity anode active compositions and high specific capacity cathode active compositions. In particular, specific electrode designs provide for achieving very high energy densities. Furthermore, the complex behavior of the active materials is used advantageously in a radical electrode balancing design that significantly reduced wasted electrode capacity in either electrode when cycling under realistic conditions of moderate to high discharge rates and/or over a reduced depth of discharge.
FILED Tuesday, August 29, 2017
APPL NO 15/689261
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/24 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/0217 (20130101)
H01M 4/131 (20130101) Original (OR) Class
H01M 4/134 (20130101)
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 10/052 (20130101)
H01M 10/446 (20130101)
H01M 10/0562 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 10686597 Lampkins et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Joshua D. Lampkins (Gardena, California);  Karim El Defrawy (Santa Monica, California);  Benjamin Terner (Goleta, California);  Aleksey Nogin (Fresno, California)
ABSTRACT Described is a system for secure multiparty computation. The system uses a secret sharing protocol to share secrets among servers of a synchronous network. An Open-Semi-Robust protocol or an Open Robust protocol is used to allow the servers to open their shares of secret data. If a server is corrupt, the Open-Robust protocol is used, otherwise, the Open-Semi-Robust protocol is used. A Deal-Semi-Robust protocol or a Deal-Robust protocol is utilized by a server to distribute its shares of secret data among the other servers. If a server is corrupt, the Deal-Robust protocol is used, otherwise, the Deal-Semi-Robust protocol is used. A Recover-Semi-Robust protocol or a Recover-Robust protocol is used to allow servers that were previously corrupted to recover their shares of secret data, such that each uncorrupted server holds correct shares of secret data. If a server is corrupt, the Recover-Robust protocol is used, otherwise, the Recover-Semi-Robust protocol is used.
FILED Monday, March 05, 2018
APPL NO 15/912393
ART UNIT 2432 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/085 (20130101) Original (OR) Class
H04L 9/0894 (20130101)
H04L 2209/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 10683507 Xiao et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Yi Xiao (Miami, Florida);  Haixiang Yu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Miami, Florida);  Haixiang Yu (Miami, Florida)
ABSTRACT The subject invention provides methods, assays, and products for detecting small molecules in a sample, in particular, in both clinical and field settings. The method for detecting a small-molecule target, preferably, a synthetic cathinone in a sample comprises contacting the sample with an aptamer-based sensor selective for the small-molecule target, and detecting the small-molecule target in the sample. Specifically, the method utilizes an aptamer-based sensor comprising a dye binding to a three-way junction binding domain of an aptamer. Binding of small-molecule target to the aptamer displaces the dye, generating a spectroscopic signal that can be used for detection of the small-molecule target and quantitative measurement of the target concentration.
FILED Tuesday, February 20, 2018
APPL NO 15/900061
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 225/10 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 23/0066 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
C12N 2310/3517 (20130101)
C12N 2320/13 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10681951 Bar-Cohen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Yoseph Bar-Cohen (Pasadena, California);  Mircea Badescu (La Canada Flintridge, California);  John Rodney Wright, Jr. (Seal Beach, California)
ASSIGNEE(S)
INVENTOR(S) Yoseph Bar-Cohen (Pasadena, California);  Mircea Badescu (La Canada Flintridge, California);  John Rodney Wright, Jr. (Seal Beach, California)
ABSTRACT The invention is intended to protect football players, race car drivers and others. An apparatus that dampens impacts and prevents rapid movement of user's head protected by helmets. Two embodiments are disclosed using piston configuration. In one embodiment, the piston is moving inside a housing filled with a viscoelastic fluid and the other is a locking piston dampener mechanism.
FILED Wednesday, September 12, 2018
APPL NO 16/129482
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 13/0512 (20130101)

Hats; Head Coverings
A42B 3/06 (20130101)
A42B 3/08 (20130101)
A42B 3/142 (20130101)
A42B 3/0473 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 10682411 Monson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Non-Profit Organization (NPO)
Kentucky Science and Technology Corporation (KSTC)
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
ASSIGNEE(S) Bexion Pharmaceuticals Inc. (Covington, Kentucky)
INVENTOR(S) Ellen K. Monson (Cincinnati, Ohio);  Xiaochen Wei (Fort Mitchell, Kentucky);  Ray Takigiku (Covington, Kentucky);  Charles A. Cruze, III (West Chester, Ohio);  Joseph W. Wyse (Nicholasville, Kentucky)
ABSTRACT Disclosed are pharmaceutical compositions containing saposin C and phosphatidylserine that are useful for treating various cancers.
FILED Friday, November 02, 2018
APPL NO 16/179139
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/127 (20130101)
A61K 38/18 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101) Original (OR) Class
A61K 47/18 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 16, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200616.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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