FedInvent™ Patents
Patent Details for Tuesday, June 23, 2020
This page was updated on Monday, March 27, 2023 at 06:07 AM GMT
Department of Health and Human Services (HHS)
| US 10687520 | Min et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yi-Li Min (Dallas, Texas); Rhonda Bassel-Duby (Dallas, Texas); Eric Olson (Dallas, Texas) |
| ABSTRACT | Duchenne muscular dystrophy (DMD), which affects 1 in 5,000 male births, is one of the most common genetic disorders of children. This disease is caused by an absence or deficiency of dystrophin protein in striated muscle. The major DMD deletion “hot spots” are found between exon 6 to 8, and exons 45 to 53. Here, a “humanized” mouse model is provided that can be used to test a variety of DMD exon skipping strategies. Among these are, CRISPR/Cas9 oligonucleotides, small molecules or other therapeutic modalities that promote exon skipping or micro dystrophin mini genes or cell based therapies. Methods for restoring the reading frame of exon 44 deletion via CRISPR-mediated exon skipping in the humanized mouse model, in patient-derived iPS cells and ultimately, in patients using various delivery systems are also contemplated. The impact of CRISPR technology on DMD is that gene editing can permanently correct mutations. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914728 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/054 (20130101) A01K 2217/056 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/465 (20130101) A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 15/8509 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687525 | Campbell et al. |
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| FUNDED BY |
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| APPLICANT(S) | TISSUE TESTING TECHNOLOGIES LLC (North Charleston, South Carolina) |
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| INVENTOR(S) | Lia H. Campbell (Mount Pleasant, South Carolina); Kelvin G M Brockbank (Charleston, South Carolina) |
| ABSTRACT | Living cellular material may be preserved by incubating the cellular material in a culture medium containing at least one glycolipid, and then subjecting the cellular material to a preservation protocol. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 15/655381 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0252 (20130101) A01N 1/0284 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687710 | Blank et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Molly Blank (Pittsburgh, Pennsylvania); James Antaki (Pittsburgh, Pennsylvania) |
| ABSTRACT | A palpation device for palpation of tissues for characterization (e.g., qualification and/or quantification) of subcutaneous structures is provided. The palpation device includes a frame formed from a substantially rigid material and comprising an opening; a tonometric lens extending through the opening of the frame; and a radiation source. The lens is configured to at least partially impinge a tissue of interest to identify an object embedded therein. The lens includes a body having a reflective coating on an outer surface thereof. The radiation source is positioned to illuminate the reflective coating such that a topography of the coating can be observed. The body includes a body material that is as stiff or stiffer than the tissue of interest and less stiff than the embedded object to be characterized. A system including the palpation device and an image device for obtaining an image through the lens is also provided. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 15/318703 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/4312 (20130101) A61B 5/6885 (20130101) A61B 5/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687785 | Konofagou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERISTY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Jean Provost (Paris, France) |
| ABSTRACT | Systems and methods for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure are provided. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition can detect the movement of the body structure without inducing such movement. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 15/048761 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/08 (20130101) A61B 8/463 (20130101) A61B 8/485 (20130101) A61B 8/0883 (20130101) Original (OR) Class A61B 8/5223 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52042 (20130101) G01S 7/52087 (20130101) G01S 15/8925 (20130101) G01S 15/8956 (20130101) G01S 15/8977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687898 | Trayanova et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Patrick M. Boyle (Baltimore, Maryland); Sohail Zahid (Baltimore, Maryland) |
| ABSTRACT | According to some embodiments of the invention, a method for providing an atrial fibrillation (AF) ablation treatment plan includes receiving imaging data for at least a portion of an atrial region of a subject's heart, and processing the imaging data to characterize tissue as one of fibrotic tissue or non-fibrotic tissue. The method further includes calculating a metric of spatial distribution of at least a portion of the tissue characterized as fibrotic tissue from the processing the imaging data, identifying a cardiac tissue ablation target based on the metric, and providing an AF treatment plan that includes the cardiac tissue ablation target as at least a portion of the AF treatment plan. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 15/526199 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7275 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/5217 (20130101) A61B 18/1492 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 2018/00351 (20130101) A61B 2018/00357 (20130101) A61B 2018/00363 (20130101) A61B 2018/00577 (20130101) A61B 2034/104 (20160201) A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687942 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | June-Hong Kim (North Bethesda, Maryland); Robert J. Lederman (Chevy Chase, Maryland); Ozgur Kocaturk (Rockville, Maryland) |
| ABSTRACT | Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. A protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954555 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2451 (20130101) Original (OR) Class A61F 2210/0014 (20130101) A61F 2220/0075 (20130101) A61F 2230/0045 (20130101) A61F 2250/001 (20130101) A61F 2250/0004 (20130101) A61F 2250/0037 (20130101) A61F 2250/0065 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0041 (20130101) A61M 2025/0042 (20130101) A61M 2025/0059 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10687976 | Chin et al. |
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| FUNDED BY |
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| APPLICANT(S) | HydroGlyde Coatings LLC (Brookline, Massachusetts) |
| ASSIGNEE(S) | HydroGlyde Coatings LLC (Brookline, Massachusetts) |
| INVENTOR(S) | Stacy Lee Chin (Brookline, Massachusetts); Benjamin Goldman Cooper (Lynnfield, Massachusetts); Ruiqing Xiao (Boston, Massachusetts); Mark W. Grinstaff (Brookline, Massachusetts) |
| ABSTRACT | The invention provides a novel hydrophilic polymer and latex polymer blend coating formulation and compositions thereof, and their use on various devices (e.g., prophylactic and medical devices) to form hydrophilic and flexible coatings with durable lubricity. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782262 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 6/04 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/22 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/26 (20130101) B32B 27/28 (20130101) B32B 27/30 (20130101) B32B 27/36 (20130101) B32B 27/285 (20130101) B32B 27/302 (20130101) B32B 27/306 (20130101) B32B 2307/728 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/042 (20130101) C08J 2300/26 (20130101) C08J 2307/00 (20130101) C08J 2307/02 (20130101) C08J 2347/00 (20130101) C08J 2407/02 (20130101) C08J 2409/02 (20130101) Compositions of Macromolecular Compounds C08L 7/02 (20130101) C08L 9/08 (20130101) C08L 11/02 (20130101) C08L 29/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 107/02 (20130101) C09D 109/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688039 | Radhakrishnan et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Kirthi Radhakrishnan (Cincinnati, Ohio); Christy K. Holland (Cincinnati, Ohio); Kevin J. Haworth (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions for treating a patient for a condition characterized by an excess blood concentration of dissolved gas in at least one targeted region of the patient are provided. The method comprises administering a composition comprising a perfluorocarbon droplet emulsion into the blood of the patient; insonifying the at least one target region sufficient to achieve formation of microbubbles by droplet vaporization of at least a portion of the perfluorocarbon droplets present in the blood; whereby a concentration gradient favoring movement of gas molecules from the blood into the microbubbles is established for a time frame. |
| FILED | Friday, August 26, 2016 |
| APPL NO | 15/754077 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) Original (OR) Class A61K 9/107 (20130101) A61K 31/02 (20130101) A61K 47/24 (20130101) A61K 47/6925 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2007/0039 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4925 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688045 | Popov et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Alexey Popov (Waltham, Massachusetts); Elizabeth M. Enlow (Waltham, Massachusetts); Hongming Chen (Belmont, Massachusetts); James Bourassa (Somerville, Massachusetts) |
| ABSTRACT | Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 15/808746 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 9/5031 (20130101) A61K 9/5123 (20130101) A61K 9/5138 (20130101) A61K 9/5146 (20130101) A61K 31/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688061 | Vyavahare et al. |
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| FUNDED BY |
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| APPLICANT(S) | Clemson University (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Naren Vyavahare (Greenville, South Carolina); Aditi Sinha (Clemson, South Carolina) |
| ABSTRACT | Methods and delivery agents for treatment of connective tissue that includes elastic fibers are described. Delivery agents are nano- or micro-sized particles that include a biologically active compound useful in treatment of degraded elastic fibers and an anchoring agent at a surface that binds at or near the area of degraded elastic fibers. The delivery agents may be utilized for targeted delivery of biologically active compounds to degraded elastic fibers so as to maintain and/or regenerate the elastin component of connective tissue, and prevent further degradation and/or rehabilitate the structural architecture of the connective tissue. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/421604 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 39/44 (20130101) A61K 47/02 (20130101) A61K 47/6843 (20170801) A61K 47/6937 (20170801) Peptides C07K 16/18 (20130101) C07K 16/2836 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688063 | Farese et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); The United States Government as Represented by the Department of Veterans Affairs of General Counsel- PSG IV (024) (Washington, District of Columbia) |
| INVENTOR(S) | Robert Vito Farese (St. Petersburg, Florida); Mini Paliyath Sajan (Wesley Chapel, Florida) |
| ABSTRACT | Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD). |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/730423 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) Original (OR) Class A61K 31/341 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688077 | Wei et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Sheng Wei (Tampa, Florida); Alan List (Tampa, Florida) |
| ABSTRACT | Disclosed are methods for treating a meylodysplastic syndrome (MDS) in a subject that involves administering to the subject a therapeutically effective amount of an inflammasome inhibitor. Also disclosed are methods for diagnosing a myelodysplastic syndrome (MDS) in a subject. In some embodiments, the method involves assaying a sample from the subject to detect inflammasome activation, wherein an increase in inflammasome activation in the sample compared to a control is an indication of MDS in the subject. In some embodiments, the method involves assaying a sample from the subject to detect s100A9 protein levels, wherein an increase in s100A9 protein levels in the sample compared to a control is an indication of MDS in the subject. The disclosed methods can further involve treating the subject for MDS if an increase in inflammasome activation and/or s100A9 levels are detected. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/552578 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/34 (20130101) A61K 31/34 (20130101) A61K 31/64 (20130101) A61K 31/64 (20130101) A61K 31/341 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/57426 (20130101) G01N 2333/4727 (20130101) G01N 2333/96466 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688080 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yu Chen (Tampa, Florida); Nicholas Joseph Torelli (Denver, Colorado); Orville Antonio Pemberton (Tampa, Florida); Xiujun Zhang (Lutz, Florida); Adam Renslo (San Francisco, California); Kyle Defrees (San Francisco, California); Priyadarshini Jaishankar (Newark, California) |
| ABSTRACT | The present disclosure provides compositions including a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049164 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) Original (OR) Class A61K 31/41 (20130101) A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 257/06 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688083 | Glenn et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eiger Group International, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | Eiger Group International, Inc. (Palo Alto, California) |
| INVENTOR(S) | Jeffrey S. Glenn (Palo Alto, California); Edward A. Pham (Shaker Heights, Ohio) |
| ABSTRACT | Disclosed herein are methods for use of R-chloroquine or clemizole or combinations of R-chloroquine and clemizole for the treatment of a subject in need thereof. Uses include methods of treating inflammatory′ conditions, treating liver cancer or reducing the risk of developing liver cancer in a subject. Uses also include methods of treating non-alcoholic steatohepatitis in a subject. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/738827 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4706 (20130101) A61K 31/4706 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 29/00 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 215/46 (20130101) C07D 235/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688096 | Snyder et al. |
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| FUNDED BY |
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| APPLICANT(S) | Solomon H. Snyder (Baltimore, Maryland); Moataz M. Gadalla (Baltimore, Maryland); Nanduri R. Prabhakar (Chicago, Illinois); Gregory Stein (San Diego, California); Gary Pace (La Jolla, California) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Solomon H. Snyder (Baltimore, Maryland); Moataz M. Gadalla (Baltimore, Maryland); Nanduri R. Prabhakar (Chicago, Illinois); Gregory Stein (San Diego, California); Gary Pace (La Jolla, California) |
| ABSTRACT | Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditions. |
| FILED | Monday, April 11, 2011 |
| APPL NO | 13/640711 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/24 (20130101) A61K 31/28 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/198 (20130101) A61K 31/385 (20130101) A61K 31/385 (20130101) A61K 31/404 (20130101) A61K 31/409 (20130101) A61K 31/409 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4164 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688098 | Southerland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee) |
| ASSIGNEE(S) | Meharry Medical College (Nashville, Tennessee) |
| INVENTOR(S) | Janet H. Southerland (Nashville, Tennessee); Pandu R. Gangula (Nashville, Tennessee) |
| ABSTRACT | Pharmaceutical compositions and methods of treatment or prevention of diseases and conditions associated with or characterized by at least one of xerostomia and periodontal disease by modulation of the nitric oxide synthase pathway are provided, as are animal models and drug screening methods. Such modulation may be achieved by the administration of tetrahydrobiopterin (BH4) or its prodrugs and/or salts. Treating and preventing xerostomia can have the downstream effect of also preventing periodontitis, dental caries, parotid gland enlargement, inflammation and fissuring of the lips (chelitis), inflammation or ulcers of the tongue and buccal mucosa, oral candidiasis, salivary gland infection (sialadenitis), halitosis, and cracking and fissuring of oral mucosa. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/213894 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/10 (20130101) A61K 9/0056 (20130101) A61K 9/0058 (20130101) A61K 9/0063 (20130101) A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 5/48 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688109 | Oates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | John A. Oates (Nashville, Tennessee); Olivier Boutaud (Nashville, Tennessee); Irene Zagol-Ikapitte (Nashville, Tennessee) |
| ABSTRACT | A method of preventing or reducing the occurrence of malondiadehyde and/or levuglandin protein modification in a subject in need thereof, comprising administering to said subject an effective amount of at least one γ-KA scavenger compound, or a pharmaceutically acceptable salt thereof. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/200403 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/609 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 7/02 (20180101) A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688130 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Saul A. Villeda (Lancaster, California); Joseph M. Castellano (San Mateo, California); Jinte Middeldorp (Utrecht, Netherlands); Martin S. Angst (Stanford, California); Jian Luo (Palo Alto, California) |
| ABSTRACT | Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention. |
| FILED | Friday, December 05, 2014 |
| APPL NO | 14/562401 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688136 | Quarta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Marco Quarta (Palo Alto, California); Thomas A. Rando (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for induction and maintenance of quiescence of stem cells. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/600270 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 2500/25 (20130101) C12N 2500/90 (20130101) C12N 2501/15 (20130101) C12N 2501/34 (20130101) C12N 2501/999 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688150 | Janssen-Heininger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The Univserity of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Yvonne M. Janssen-Heininger (Charlotte, Vermont); Vikas Anathy (Essex Junction, Vermont) |
| ABSTRACT | The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, a subject having pulmonary fibrosis. In some embodiments, an inhibitor of ERp57 (for example, thiomuscimol) and/or an inhibitor of GSTP (for example, TLK-199) may be used to treat the subject. Also provided in certain aspects of the present invention are kits for such therapies, methods for promoting such therapies, and the like. |
| FILED | Thursday, January 18, 2018 |
| APPL NO | 15/874136 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/425 (20130101) A61K 31/425 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/713 (20130101) A61K 38/06 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 38/45 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 205/01018 (20130101) C12Y 503/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688152 | Al-Harthi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUSH UNIVERSITY MEDICAL CENTER (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Lena Al-Harthi (Chicago, Illinois) |
| ABSTRACT | One aspect of the present invention provides methods of treating a viral infection in a subject including administrating a therapeutically effective amount of at least one Wnt ligand protein selected from Wnt1, Wnt2, Wnt2B, Wnt3, Wnt3A, Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A, Wnt7B, Wnt8A, Wnt8B, Wnt9A, Wnt9B, Wnt10A, Wnt10B, Wnt11 and Wnt16. In one embodiment, the subject is a human and the infection is a human immunodeficiency virus infection. Another aspect provides drug combinations for treating viral infections. |
| FILED | Friday, September 18, 2015 |
| APPL NO | 15/510902 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) A61P 31/22 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688154 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jian Luo (Palo Alto, California); Anton Wyss-Coray (Palo Alto, California) |
| ABSTRACT | The present invention provides methods for preventing, attenuating neuronal damage or stimulating neuronal repair prior or following central nervous system injury. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687175 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class A61K 38/193 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688162 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CellSNAP LLC (Madison, Wisconsin) |
| ASSIGNEE(S) | CELLSNAP LLC (Madison, Wisconsin) |
| INVENTOR(S) | Eric A. Johnson (Madison, Wisconsin); Sabine Pellett (Madison, Wisconsin); William H. Tepp (Madison, Wisconsin); Marite Bradshaw (Madison, Wisconsin); Christina L. Pier (Madison, Wisconsin); Joseph T. Barbieri (Madison, Wisconsin) |
| ABSTRACT | The present disclosure relates to chimeric neurotoxins and uses thereof. In particular, provided herein are chimeric botulinum neurotoxins with altered properties and uses thereof (e.g., research, screening, and therapeutic uses). |
| FILED | Wednesday, January 10, 2018 |
| APPL NO | 15/866895 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4893 (20130101) Original (OR) Class Peptides C07K 14/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Enzymes C12Y 304/24069 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688164 | Nelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Jay Nelson (Lake Oswego, Oregon); Scott Hansen (Portland, Oregon); Meaghan H. Hancock (Aloha, Oregon); Louis Picker (Portland, Oregon); Klaus Frueh (Portland, Oregon) |
| ABSTRACT | Disclosed herein are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an active UL128 protein and an active UL130 protein. Also disclosed are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an inactive UL128 protein and an inactive UL130 protein. Also disclosed are methods of generating an unconventional immune response using these vectors. Such an immune response is characterized by generation of a CD8+ T cell response that is predominantly restricted by MHC-II. |
| FILED | Sunday, November 20, 2016 |
| APPL NO | 15/356627 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/16134 (20130101) C12N 2710/16143 (20130101) C12N 2710/16162 (20130101) C12N 2740/15034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688181 | Kipps et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Thomas J. Kipps (San Diego, California); Liguang Chen (San Diego, California); Bing Cui (San Diego, California) |
| ABSTRACT | There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically effective amount of a Bruton's tyrosine kinase (BTK) antagonist and a ROR-1 antagonist. Further provided are pharmaceutical compositions including a BTK antagonist, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the BTK antagonist is ibrutinib and the ROR-1 antagonist is cirmtuzumab. |
| FILED | Tuesday, June 27, 2017 |
| APPL NO | 15/634802 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2803 (20130101) C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688198 | Ray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Sangeeta Ray (Ellicott City, Maryland); Xing Yang (Baltimore, Maryland); Xiaolei Song (Baltimore, Maryland); Michael T. McMahon (Columbia, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | Salicylic acid-based polymeric CEST contrast agents targeting prostate-specific membrane antigen, pharmaceutical composition comprising the same and methods of use thereof are disclosed. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/764316 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0039 (20130101) A61K 49/0043 (20130101) Original (OR) Class A61K 49/0054 (20130101) A61K 49/085 (20130101) A61K 49/124 (20130101) A61K 49/146 (20130101) A61K 51/065 (20130101) A61K 2123/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/04 (20130101) C07F 5/00 (20130101) C07F 5/02 (20130101) C07F 5/003 (20130101) C07F 19/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688202 | Wall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Matthew A. Wall (New York, New York); Travis Shaffer (New York, New York); Stefan Harmsen (New York, New York); Jan Grimm (New York, New York); Moritz F. Kircher (New York, New York) |
| ABSTRACT | The present disclosure, among other things, provides new technologies for preparation of medical isotope labeled metal(loid) chalcogen nanoparticles for use in medical imaging and/or therapeutic applications. Provided technologies show a number of advantages as compared with previously available options for preparing and utilizing medical isotopes, including, for example, they utilize metal(loid) chalcogen nanoparticles that serve as universal binders (e.g., via covalent or non-covalent (e.g., chelate) bonds) for medical isotopes to provide medical isotope labeled metal(loid) chalcogen nanoparticles. Surprisingly, the same metal(loid) chalcogen nanoparticles may be used to bind (e.g., covalent or non-covalent e.g., chelation) bonding) a wide variety of different useful medical isotopes without the use of traditional chelating agents. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 15/329876 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/025 (20130101) A61K 51/1244 (20130101) Original (OR) Class A61K 51/1251 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688223 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University a Congressionally Chartered Not-for-Profit Corporation (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University, a Congressionally Chartered Not-for-Profit Corporation (Washington, District of Columbia) |
| INVENTOR(S) | Haitao Cui (Arlington, Virginia); Wei Zhu (Washington, District of Columbia); Benjamin Holmes (Washington, District of Columbia); Lijie Grace Zhang (Arlington, Virginia) |
| ABSTRACT | Embodiments of the present invention relate to structures and systems having a three-dimensional biomimetic structure with a porous biomimetic three-dimensional scaffold and a coating deposited onto a surface of the porous biomimetic three-dimensional scaffold as well as methods of using and fabricating the like. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650397 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) A61F 2/28 (20130101) A61F 2002/2817 (20130101) A61F 2002/3092 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/28 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 31/00 (20130101) A61L 2300/414 (20130101) A61L 2420/04 (20130101) A61L 2430/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688257 | Yeates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KAER BIOTHERAPEUTICS CORPORATION (Escondido, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donovan B Yeates (Escondido, California); Xin Heng (McKinney, Texas) |
| ABSTRACT | A system and a method for generating a respirable dry powder aerosol (15) from a liquid solution or liquid suspension at a respirable dry powder aerosol volume flow (91). A liquid aerosol generating nozzle (3) generates from the liquid solution or liquid suspension a liquid aerosol (13) that is diluted by dilution gas (4) and dried in a cylindrical evaporation chamber (6) to generate a dry powder aerosol (14) that is subsequently concentrated. The system and method may include heliox as a gas, specifically dilution gas (4), for enhancing both the drying process in the cylindrical evaporation chamber (6) and for enhancing the concentration efficiency, but also as a nozzle gas (2) for enhancing generating the liquid aerosol (13) from the liquid solution or liquid suspension. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/947703 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/002 (20140204) A61M 11/02 (20130101) Original (OR) Class A61M 11/006 (20140204) A61M 11/06 (20130101) A61M 15/0086 (20130101) A61M 16/125 (20140204) A61M 2202/0007 (20130101) A61M 2202/064 (20130101) A61M 2202/0208 (20130101) A61M 2202/0488 (20130101) A61M 2202/0488 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/0416 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688302 | Harkema et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Susan J. Harkema (Louisville, Kentucky); Yangshen Chen (Louisville, Kentucky); Manikandan Ravi (Louisville, Kentucky); Claudia Angeli (Louisville, Kentucky); Charles Hubscher (Louisville, Kentucky) |
| ABSTRACT | Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction. |
| FILED | Thursday, August 18, 2016 |
| APPL NO | 15/752307 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/0553 (20130101) A61N 1/3611 (20130101) A61N 1/36003 (20130101) A61N 1/36007 (20130101) A61N 1/36062 (20170801) Original (OR) Class A61N 1/36103 (20130101) A61N 1/36107 (20130101) A61N 1/36114 (20130101) A61N 1/36125 (20130101) A61N 1/36185 (20130101) A61N 1/37211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688556 | Matsui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Hiroshi Matsui (Glen Rock, New Jersey); Zengyan Wei (Corona, New York); Justin Fang (New York, New York) |
| ABSTRACT | Nanocages are formed by etching nancubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477601 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) Original (OR) Class B22F 1/0022 (20130101) B22F 1/0062 (20130101) B22F 1/0085 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 9/24 (20130101) B22F 2001/0037 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/00 (20130101) C23F 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688656 | Alambeigi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Farshid Alambeigi (Ghazvin, Iran); Reza Seifabadi (Baltimore, Maryland); Mehran Armand (Maple Lawn, Maryland) |
| ABSTRACT | A continuum device/manipulator includes a first flexible tube, a low melting point (LMP) alloy disposed within the first flexible tube, and a temperature adjustment element that applies heat or cooling to change a phase of the LMP alloy. Changing the phase of the LMP alloy controls a flexibility of the first flexible tube. |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/091822 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0051 (20130101) A61B 1/0055 (20130101) A61B 1/00078 (20130101) A61B 1/128 (20130101) A61B 2017/00411 (20130101) A61B 2017/00955 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/005 (20130101) A61M 25/0054 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) Original (OR) Class B25J 9/065 (20130101) B25J 9/1095 (20130101) B25J 15/12 (20130101) B25J 18/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689329 | Navarro Fernandez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Oscar Navarro Fernandez (Tigard, Oregon); Carmem Pfeifer (Beaverton, Oregon); Ana Paula Piovezan Fugolin (Portland, Oregon); Jack Ferracane (Beaverton, Oregon) |
| ABSTRACT | The present invention provides tertiary amine core-bearing acrylamides and their use in adhesive formulations, particularly including dental adhesives. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/361764 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/30 (20200101) A61K 6/887 (20200101) Acyclic or Carbocyclic Compounds C07C 233/38 (20130101) Original (OR) Class Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 133/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689335 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Binghe Wang (Marietta, Georgia); Yueqin Zheng (Atlanta, Georgia); Kaili Ji (Brookhaven, Georgia); Bingchen Yu (Atlanta, Georgia); Zhixiang Pan (Brookhaven, Georgia) |
| ABSTRACT | The present invention provides methods of forming hydrogen sulfide. The methods include contacting a precursor compound with an unmasking agent; wherein the precursor compound comprises a hydrogen sulfide releasing moiety and a masked nucleophile; and wherein the contacting is conducted under conditions sufficient for cyclization of the precursor compound via lactone or lactam formation; thereby releasing hydrogen sulfide from the precursor compound. Hydrogen sulfide precursor compounds according to Formula I are also described, as well as methods for treating diseases and conditions using hydrogen sulfide precursors. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/563887 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 3/08 (20180101) A61P 7/02 (20180101) A61P 9/00 (20180101) A61P 9/10 (20180101) A61P 9/12 (20180101) A61P 11/00 (20180101) A61P 11/06 (20180101) A61P 13/02 (20180101) A61P 13/08 (20180101) A61P 13/12 (20180101) A61P 15/10 (20180101) A61P 19/02 (20180101) A61P 25/00 (20180101) A61P 25/16 (20180101) A61P 25/28 (20180101) A61P 27/02 (20180101) A61P 29/00 (20180101) A61P 35/00 (20180101) A61P 37/00 (20180101) Non-metallic Elements; Compounds Thereof; C01B 17/16 (20130101) Acyclic or Carbocyclic Compounds C07C 323/62 (20130101) C07C 327/12 (20130101) Original (OR) Class C07C 381/00 (20130101) C07C 2601/02 (20170501) C07C 2602/08 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/12 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689344 | Blagg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Brian S. J. Blagg (Lawrence, Kansas); Huiping Zhao (Lawrence, Kansas) |
| ABSTRACT | Compounds of the formulas are provided: wherein variables Y1-Y5, X1-X5, A1-A4, X, y, n1, n2, and R1-R15 are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds are useful for the treatment of a disease or disorder, including, for example, a proliferative disease, such as cancer. |
| FILED | Friday, November 07, 2014 |
| APPL NO | 15/034957 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/46 (20130101) A61K 31/167 (20130101) A61K 31/445 (20130101) A61K 31/454 (20130101) A61K 31/4458 (20130101) A61K 31/4465 (20130101) A61K 31/4535 (20130101) A61K 31/4545 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 235/56 (20130101) Heterocyclic Compounds C07D 207/08 (20130101) C07D 211/22 (20130101) C07D 211/46 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 409/12 (20130101) C07D 451/06 (20130101) C07D 487/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689357 | Malamas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Michael S. Malamas (Jamison, Pennsylvania); Alexandros Makriyannis (Watertown, Massachusetts); Shrouq I. Farah (Everett, Massachusetts); Alexander M. Zvonok (Revere, Massachusetts); Shakiru Olajire Alapafuja (Braintree, Massachusetts) |
| ABSTRACT | Disclosed herein are compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof. Values for the variables in Structural Formula I are described herein. The compounds can be used to modulate (e.g., inhibit) N-acylethanolamine hydrolyzing acid amidase (NAAA) and thereby treat a variety of diseases, disorders and conditions mediated by NAAA, such as a gastrointestinal motility disorder, irritable bowel syndrome, an inflammatory bowel disorder, neuroinflammation, nicotine addiction, cancer, opioid dependence, analgesia, chemotherapy-induced neuropathic pain and pain. Also disclosed herein are compositions and methods including compounds of Structural Formula I, or a pharmaceutically acceptable salt thereof. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406613 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 331/26 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 213/16 (20130101) C07D 263/34 (20130101) C07D 401/04 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689366 | Melnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Ari M. Melnick (New York, New York); Lorena Fontan Gabas (New York, New York); Nathanael S. Gray (Boston, Massachusetts); David A. Scott (Newton, Massachusetts); John Hatcher (Marlborough, Massachusetts); Guangyan Du (Jamaica Plain, Massachusetts) |
| ABSTRACT | Provided herein are bifunctional compounds that inhibit MALT1 and/or promote targeted ubiquitination for the degradation of MALT1. In particular, provided are compounds that can bind MALT1, a protein whose activity is responsible for constitutive NF-KB signaling in certain cancers (e.g., activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL)), and can assist in its degradation by recruiting an E3 ubiquitin ligase (e.g., Cereblon, VHL), which can ubiquitinate MALT1, marking it for proteasome degradation. Also provided are pharmaceutical compositions comprising the bifunctional compounds, methods of treating cancer with the bifunctional compounds, methods of promoting the degradation of MALT1, and methods of binding E3 ubiquitin ligase activity in a subject by administering a compound or composition described herein. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 16/346483 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689381 | Boger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (LaJolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Dale Boger (LaJolla, California) |
| ABSTRACT | A vinca alkaloid compound substituted at the 20′-position with a carboxamido group is disclosed. The carbonyl of the carboxamido group is bonded to a 20′-amino group and to a ring system that contains up to three 5-, 6- or 7-membered rings that are fused or otherwise bonded together. Each ring can be carbocyclic or heterocyclic, with a heterocyclic ring containing up to three hetero ring atoms that are the same or different and are selected from nitrogen, oxygen and sulfur. The ring system can include up to four substituent groups other than hydrogen that are discussed within. Methods of preparing the compounds are disclosed as are compositions for their use and methods of treatment using d compound. A particularly preferred compound has an activity in specified cancer cell growth inhibition assays that is the same or better than its parental, unsubstituted vinca compound and is not subject to Pgp-mediated efflux. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052307 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Heterocyclic Compounds C07D 471/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689386 | Gangjee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | A compound of Formula I, or optionally a salt or a hydrate of the compound of Formula I is provided: wherein X is one selected from the group consisting of wherein R is an alkyl group having from one to six carbon atoms, and wherein R2 is a halogen atom. A pharmaceutical composition comprising a compound of Formula I, or optionally a salt or a hydrate of the compound of Formula I, and a pharmaceutically acceptable carrier, is provided. A method of treating a patient with cancer is set forth including administering a therapeutically acceptable amount of the compound of Formula I, or a salt or a hydrate of the compound of Formula I, or a pharmaceutical composition comprising a compound of Formula I. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294372 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689392 | Theodorescu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Dan Theodorescu (Englewood, Colorado); Michael Fitzpatrick Wempe (Aurora, Colorado); David Ross (Niwot, Colorado); Samy Meroueh (Westfield, Indiana); Martin A. Schwartz (Earlysville, Virginia); Phillip Reigan (Denver, Colorado) |
| ABSTRACT | The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142011 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) A61K 31/437 (20130101) A61K 31/505 (20130101) A61K 31/4162 (20130101) A61K 31/5513 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 491/052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689397 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Reuben J. Shaw (La Jolla, California); Daniel F. Egan (La Jolla, California); Nicholas Cosford (La Jolla, California); Benjamin Turk (New Haven, Connecticut); Mitchell Vamos (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Matthew Chun (La Jolla, California); Douglas Sheffler (La Jolla, California) |
| ABSTRACT | In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/269468 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/34 (20130101) C07D 239/42 (20130101) C07D 239/47 (20130101) C07D 239/48 (20130101) C07D 239/557 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) Original (OR) Class Peptides C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/11001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/912 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689412 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Jian Wu (New York, New York); Zengmin Li (Flushing, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Jian Wu (New York, New York); Zengmin Li (Flushing, New York) |
| ABSTRACT | This invention provides a process of labeling a polynucleotide analogue to be detected by Raman and/or infrared spectroscopy detection. |
| FILED | Tuesday, April 18, 2017 |
| APPL NO | 15/490823 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) Original (OR) Class C07H 19/16 (20130101) C07H 21/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 2525/101 (20130101) C12Q 2525/101 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2565/632 (20130101) C12Q 2565/632 (20130101) C12Q 2565/632 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689420 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); Terence Flotte (Holden, Massachusetts); Jun Xie (Shrewsbury, Massachusetts) |
| ABSTRACT | The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019636 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 35/76 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689425 | Panitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alyssa Panitch (Davis, California); John Eric Paderi (San Francisco, California); Kinam Park (West Lafayette, Indiana); Katherine Allison Stuart (San Francisco, California); Steve Higbee (West Lafayette, Indiana) |
| ABSTRACT | This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/369489 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/3804 (20130101) A61L 2300/25 (20130101) A61L 2300/42 (20130101) Peptides C07K 9/00 (20130101) C07K 9/001 (20130101) C07K 14/00 (20130101) C07K 14/78 (20130101) C07K 14/4725 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689432 | Zang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | Xingxing Zang (New York, New York); Hyungjun Jeon (Fort Lee, New Jersey) |
| ABSTRACT | Methods are disclosed for preventing and/or treating cardiovascular diseases comprising administering B7x or a derivative of B7x to a patient in need thereof. |
| FILED | Tuesday, December 09, 2014 |
| APPL NO | 15/100995 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) Peptides C07K 14/70532 (20130101) Original (OR) Class C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/56972 (20130101) G01N 2333/705 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689433 | Leighton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Crystal Bioscience Inc. (San Diego, California) |
| ASSIGNEE(S) | CRYSTAL BIOSCIENCE INC. (San Diego, California) |
| INVENTOR(S) | Philip A. Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California) |
| ABSTRACT | A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/723075 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Peptides C07K 16/00 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689446 | Meza-Romero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Roberto Meza-Romero (Beaverton, Oregon); Gil Benedek (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ABSTRACT | Disclosed are recombinant CD74 polypeptides mutated relative to the naturally occurring CD74 polypeptides with improved properties such as binding of CD74 ligands such as MIF and RTL1000 as well as polynucleotides that encode the polypeptides, expression vectors comprising the polynucleotides, bacteria that include the expression vectors, and methods of making the recombinant polypeptides. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 15/629573 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/70539 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 2319/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689448 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GALAXY BIOTECH, LLC (Cupertino, California) |
| ASSIGNEE(S) | GALAXY BIOTECH, LLC (Cupertino, California) |
| INVENTOR(S) | Kyung Jin Kim (Cupertino, California); Wei-meng Zhao (Palo Alto, California); Hangil Park (San Francisco, California); Maximiliano Vasquez (Palo Alto, California) |
| ABSTRACT | The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient. |
| FILED | Thursday, October 18, 2018 |
| APPL NO | 16/164530 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/51 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689456 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Qiong J. Wang (Potomac, Maryland); Zhiya Yu (Potomac, Maryland); James C. Yang (Bethesda, Maryland) |
| ABSTRACT | The invention provides a chimeric antigen receptor (CAR) having antigenic specificity for CD70, the CAR comprising: an antigen binding-transmembrane domain comprising a CD27 amino acid sequence lacking all or a portion of the CD27 intracellular T cell signaling domain; a 4-1BB intracellular T cell signaling domain; a CD3ζ intracellular T cell signaling domain; and optionally, a CD28 intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 15/531626 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/7153 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/2875 (20130101) C07K 2317/60 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689462 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David H. Thompson (West Lafayette, Indiana); Aditya Kulkarni (West Lafayette, Indiana); Christopher Collins (West Lafayette, Indiana); Yawo Mondjinou (West Lafayette, Indiana) |
| ABSTRACT | Various embodiments of the present invention are directed to polyrotaxanes comprising a poloxamer core and at least one cyclodextrin and methods for treating Niemann-Pick type C (NPC) and imaging (e.g., MRI) using the polyrotaxanes various embodiments of the present invention. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978872 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) A61K 31/765 (20130101) A61K 47/60 (20170801) A61K 47/61 (20170801) A61K 47/547 (20170801) A61K 47/6951 (20170801) A61K 51/065 (20130101) A61K 51/1268 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0015 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689595 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF MASSACHUSETTS (Amherst, Massachusetts) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Guodong Zhang (Amherst, Massachusetts); Bruce Hammock (Davis, California); Sung Hee Hwang (Davis, California); Weicang Wang (Amherst, Massachusetts) |
| ABSTRACT | The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 16/275293 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 51/09 (20130101) C07C 51/09 (20130101) C07C 59/42 (20130101) C07C 67/303 (20130101) C07C 67/303 (20130101) C07C 67/343 (20130101) C07C 67/343 (20130101) C07C 69/732 (20130101) C07C 69/732 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/14 (20130101) C11C 3/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689616 | Sentman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (West Lebanon, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/815197 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689617 | Sentman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (West Lebanon, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/815261 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689618 | Sentman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 15/948303 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689619 | Sentman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966103 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689628 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi Tang (San Gabriel, California); Xue Gao (Los Angeles, California); Xinkai Xie (Los Angeles, California) |
| ABSTRACT | The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD acyltransferase polypeptide can be engineered to exhibit properties that facilitate their use in the production of simvastatin and/or huvastatin. The materials and processes disclosed herein are designed so that fermentation facilitates lovastatin being converted to simvastatin and related compounds with minimal modifications. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277921 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689633 | Daniell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Winter Park, Florida) |
| ABSTRACT | Disclosed herein are materials useful for degrading plant biomass material. In exemplary embodiments, the plant material comprises one or more enzymes that are expressed in plants and/or bacteria. Specifically exemplified herein are plant degrading enzymes expressed in chloroplasts. The chloroplast expressed enzymes may be provided as cocktails for use in conjunction with conventional methods of converting biomass into biofuels, such as cellulosic ethanol. In other exemplary embodiments, methods and materials are disclosed for degrading mannans. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 13/659396 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 9/2494 (20130101) C12N 15/8214 (20130101) C12N 15/8242 (20130101) C12N 15/8257 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/12 (20130101) Enzymes C12Y 302/01078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689639 | Agar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Jeffrey N. Agar (Newton, Massachusetts); Joseph Salisbury (Cranston, Rhode Island) |
| ABSTRACT | Described herein are compounds and methods for tethering proteins. For example, dimers of proteins, including SOD1 and DJ-1, are described, where the dimers are formed by the covalent bonding of a cysteine on the first monomer to a cysteine on the second monomer via a cyclic disulfide linker. The covalently attached dimers exhibit increased stabilization. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912197 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/095 (20130101) A61K 31/385 (20130101) Peptides C07K 19/00 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0089 (20130101) C12N 9/96 (20130101) Original (OR) Class Enzymes C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689642 | Townshend et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Brent Townshend (Menlo Park, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Provided herein, among other things, is an automatable procedure that employs in vitro directed evolution to create DNA sequences that encode a ligand-responsive ribozyme and which, when transcribed, can control expression of genes they are coupled to. The method also allows creation of functional RNA sequences that bind target molecules, without requiring any modification or immobilization of the target. |
| FILED | Tuesday, June 28, 2016 |
| APPL NO | 15/744718 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 15/1048 (20130101) Original (OR) Class C12N 15/1096 (20130101) C12N 2310/12 (20130101) C12N 2310/16 (20130101) C12N 2330/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689651 | Iwata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Hiroshi Iwata (Brookline, Massachusetts); Masanori Aikawa (Chestnut Hill, Massachusetts); Takuya Hara (Fuji, Japan); Sasha Singh (Boston, Massachusetts); Piero Ricchiuto (Milan, Italy); Hideo Yoshida (Brookline, Massachusetts); Iwao Yamada (Boston, Massachusetts) |
| ABSTRACT | The invention relates to compositions and methods for inhibiting macrophage activation via modulating PARP9 and/or PARP14 expression or activity, such as small molecules, RNAi and antibodies. Modulating the expression and/or activity of PARP9 and/or PARP14 allows the inhibition of monocytes or macrophage M1 activation and inflammation. Inhibiting undesirable excessive or sustained inflammation found in humans, for the treatment, prevention and/or management of conditions where undesirable excessive or sustained inflammation is known or likely to contribute to the onset, development and/or progression the conditions. |
| FILED | Friday, November 14, 2014 |
| APPL NO | 15/036249 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) Enzymes C12Y 204/0203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689652 | Stampfer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Martha R. Stampfer (Oakland, California); James C. Garbe (San Francisco, California) |
| ABSTRACT | Methods for inducing non-clonal immortalization of normal epithelial cells by directly targeting the two main senescence barriers encountered by cultured epithelial cells. In finite lifespan pre-stasis human mammary epithelial cells (HMEC), the stress-associated stasis barrier was bypassed, and in post-stasis HMEC, the replicative senescence barrier, a consequence of critically shortened telomeres, was bypassed. Early passage non-clonal immortalized lines exhibited normal karyotypes. Methods of efficient HMEC immortalization, in the absence of “passenger” genomic errors, should facilitate examination of telomerase regulation and immortalization during human carcinoma progression, methods for screening for toxic and environmental effect on progression, and the development of therapeutics targeting the process of immortalization. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/256395 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) C12N 5/0693 (20130101) C12N 15/62 (20130101) C12N 15/1136 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2501/606 (20130101) C12N 2510/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5014 (20130101) G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689660 | Schroeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Julian I. Schroeder (La Jolla, California); Cawas Engineer (San Diego, California) |
| ABSTRACT | In alternative embodiments, the invention provides compositions and methods for manipulating the exchange of water and/or carbon dioxide (CO2) through plant stomata by controlling the expression of a novel apoplastic subtilisin-like serine endopeptidase-like protein. In alternative embodiments, the invention provides plants having increased water use efficiency, and drought-resistant plants; and methods for engineering of water transpiration and water use efficiency in plants, and engineering plants with increased water use efficiency and drought-resistant plants. |
| FILED | Friday, June 21, 2013 |
| APPL NO | 14/408234 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689687 | Nolan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Garry P. Nolan (Redwood City, California); Yury Goltsev (Stanford, California); Quan Nguyen (San Ramon, California); Yunqing Ma (San Jose, California); Chunfai Lai (Fremont, California) |
| ABSTRACT | Methods of assaying cells of a cellular sample for the presence of a target nucleic acid are provided. Aspects of the methods include evaluating a cellular sample that has been contacted with a nuclease inhibitor for the presence of a target nucleic acid. Also provided are devices and kits that find use in practicing the methods described herein. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691580 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 2527/125 (20130101) C12Q 2527/137 (20130101) C12Q 2527/149 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689691 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Winston Yan (Brookline, Massachusetts); David A. Scott (Cambridge, Massachusetts); Aaron Smargon (Cambridge, Massachusetts); Mohammed Reza Mirzazadeh (Stockholm, Sweden); Nicola Crosetto (Stockholm, Sweden) |
| ABSTRACT | The invention provides for systems, methods, compositions, and kits for the complete characterization of targeted nuclease specificity which necessitates techniques that can assess the full possibility space of off-target activity and genomic stability following genome editing. Also provided are the materials and techniques which enable the comprehensive genomic stability accompanying a range of cellular perturbations, including genome editing (ZFN, TALEN, CRISPR, and future technologies) and disease modeling among other applications. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626853 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2320/11 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6855 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) C12Q 2521/301 (20130101) C12Q 2521/501 (20130101) C12Q 2525/155 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689699 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/411066 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689700 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/411068 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689701 | Tsalik et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Ephraim Tsalik (Durham, North Carolina); Vance Fowler (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Joseph E. Lucas (Chapel Hill, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Sun Hee Ahn (Gwangju, South Korea) |
| ABSTRACT | Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/214853 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689703 | Nick et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Jewish Health (Denver, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Jerry A. Nick (Denver, Colorado); Kenneth C. Malcolm (Denver, Colorado) |
| ABSTRACT | The present invention is related to novel methods for categorizing and treating subjects having Acute Respiratory Distress Syndrome (ARDS). |
| FILED | Tuesday, April 26, 2016 |
| APPL NO | 15/139119 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689709 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | JBS Science Inc. (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | JBS Science Inc. (Doylestown, Pennsylvania) |
| INVENTOR(S) | Wei Song (Audubon, Pennsylvania); Surbhi Jain (Doylestown, Pennsylvania); Jamin Dean Steffen (Yardley, Pennsylvania); Jeremy Wang (Collegeville, Pennsylvania) |
| ABSTRACT | Provided herein are a kit and method for detecting mutations in CTNNB1 and hTERT, and their use in detection and management of hepatocellular carcinoma (HCC). The kit comprises a first pair of primers, configured to specifically bind sequences flanking the genomic region for amplifying the genomic region in a first PCR reaction; and at least one clamp, each configured to bind to one first allele but not any second allele at an annealing temperature in the first PCR reaction to thereby selectively suppress amplification of the one first allele but still allow amplification of other second allele(s). Kits and methods for detecting mutations in CTNNB1 and hTERT are also provided. A method for detecting or monitoring recurrence of HCC is further disclosed, which comprises determining levels of five DNA markers, including CTNNB1 mutations, hTERT mutations, TP53 mutations, RASSF1A methylation, and GSTP1 methylation. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492385 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/163 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690651 | Srinivasan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Sujatha Srinivasan (Redmond, Washington); David N. Fredricks (Seattle, Washington) |
| ABSTRACT | The invention disclosed herein generally relates to methods and kits for diagnosing, assessing disease risk, treating, and preventing bacterial vaginosis (BV) and associated conditions. Additional embodiments include methods for developing metabolic profiles associated with increased disease risk, and developing new approaches to treat BV based on interrupting metabolic networks. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/566240 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/68 (20130101) C12Q 1/689 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/487 (20130101) Original (OR) Class G01N 33/6812 (20130101) G01N 2570/00 (20130101) G01N 2800/36 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690653 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Changchun Liu (Bala Cynwyd, Pennsylvania); Haim H. Bau (Swarthmore, Pennsylvania); Michael G. Mauk (Greelville, Delaware) |
| ABSTRACT | The present disclosure provides devices and methods using separating a fluid—e.g., plasma or serum—from whole blood. In some embodiments, the devices and methods use hydrophobic or superhydrophobic surfaces to encourage whole blood to contact a selective membrane that extracts the desired fluid component from the blood. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 15/534810 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 63/088 (20130101) B01D 2313/14 (20130101) B01D 2313/025 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2200/025 (20130101) B01L 2200/0605 (20130101) B01L 2300/161 (20130101) B01L 2300/165 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2400/0406 (20130101) B01L 2400/0463 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) G01N 33/491 (20130101) Original (OR) Class G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690683 | Mohan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Conneticut (Farmington, Connecticut) |
| INVENTOR(S) | Royce Mohan (Farmington, Connecticut); Paola Bargagna-Mohan (Farmington, Connecticut); Dennis L. Wright (Farmington, Connecticut); Santosh Keshipeddy (Farmington, Connecticut) |
| ABSTRACT | The present disclosure relates to compounds and methods for labeling and/or detecting proteins in vivo, and methods for probing mitochondrial structure and/or dynamics. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/675353 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5005 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/16 (20130101) G01N 2800/164 (20130101) G01N 2800/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690739 | Zeng et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David Y Zeng (Stanford, California); Dwight G Nishimura (Palo Alto, California) |
| ABSTRACT | A magnetic resonance imaging (MRI) techniques uses a T2-preparation outer volume suppression (OVS) pulse sequence to reduce the longitudinal magnetization outside a region of interest. A region is excited that includes the region of interest, radiofrequency (RF) signals are detected, and MRI images generated from the RF detected signals. The T2-preparation OVS pulse sequence includes, sequentially: a first tip-down excitation pulse, a first refocusing excitation pulse, a first tip-up excitation pulse that is selective spatially and/or spectrally, a second tip-down excitation pulse that is 180° out of phase with respect to the first tip-down excitation pulse, a second refocusing excitation pulse, and a second tip-up excitation pulse that is selective spatially and/or spectrally. Alternatively, the first tip-down excitation pulse is selective spatially and/or spectrally instead of the first tip-up excitation pulse, and the second tip-down excitation pulse is selective spatially and/or spectrally instead of the second tip-up excitation pulse. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/482659 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4838 (20130101) Original (OR) Class G01R 33/5602 (20130101) G01R 33/5617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691978 | Sasaki et al. |
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| FUNDED BY |
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| APPLICANT(S) | DRVision Technologies LLC (Bellevue, Washington) |
| ASSIGNEE(S) | DRVISION TECHNOLOGIES LLC (Bellevue, Washington) |
| INVENTOR(S) | Hideki Sasaki (Bellevue, Washington); Chi-Chou Huang (Redmond, Washington); Shih-Jong James Lee (Bellevue, Washington) |
| ABSTRACT | Four computerized machine learning methods for deep semantic segmentation are fast machine learning method, active machine learning method, optimal machine learning method, and optimal transfer learning method. The fast machine learning method performs a fast deep semantic segmentation learning on training images to generate a deep model. The active machine learning method performs a fast deep semantic segmentation learning on initial training images to generate a first deep model and then an active deep semantic segmentation learning to generate a second deep model. The optimal machine learning method performs a fast deep semantic segmentation learning on initial training images to generate a first deep model and then an optimal deep semantic segmentation learning to generate a second deep model. The optimal transfer learning method applies a pre-trained first deep model on transfer training images and then an optimal deep semantic segmentation transfer learning to generate a second deep model. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/010593 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/726 (20130101) G06K 9/6262 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Image Data Processing or Generation, in General G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692211 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Mehdi Alilou (Cleveland, Ohio) |
| ABSTRACT | Embodiments classify lung nodules by accessing a 3D radiological image of a region of tissue, the 3D image including a plurality of voxels and slices, a slice having a thickness; segmenting the nodule represented in the 3D image across contiguous slices, the nodule having a 3D volume and 3D interface, where the 3D interface includes an interface voxel; partitioning the 3D interface into a plurality of nested shells, a nested shell including a plurality of 2D slices, a 2D slice including a boundary pixel; extracting a set of intra-perinodular textural transition (Ipris) features from the 2D slices based on a normal of a boundary pixel of the 2D slices; providing the Ipris features to a machine learning classifier which computes a probability that the nodule is malignant, based, at least in part, on the set of Ipris features; and generating a classification of the nodule based on the probability. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/012937 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6261 (20130101) G06K 9/6269 (20130101) G06K 2209/053 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 7/194 (20170101) G06T 15/08 (20130101) G06T 2207/10081 (20130101) G06T 2207/10104 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20152 (20130101) G06T 2207/30064 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 20/40 (20180101) G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692250 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Joseph Yitan Cheng (Los Altos, California); Morteza Mardani Korani (Palo Alto, California); John M. Pauly (Stanford, California); Shreyas S. Vasanawala (Stanford, California) |
| ABSTRACT | A method for magnetic resonance imaging acquires multi-channel subsampled k-space data using multiple receiver coils; performs singular-value-decomposition on the multi-channel subsampled k-space data to produce compressed multi-channel k-space data which normalizes the multi-channel subsampled k-space data; applies a first center block of the compressed multi-channel k-space data as input to a first convolutional neural network to produce a first estimated k-space center block that includes estimates of k-space data missing from the first center block; generates an n-th estimated k-space block by repeatedly applying an (n−1)-th estimated k-space center block combined with an n-th center block of the compressed multi-channel k-space data as input to an n-th convolutional neural network to produce an n-th estimated k-space center block that includes estimates of k-space data missing from the n-th center block; reconstructs image-space data from the n-th estimated k-space block. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260921 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/4826 (20130101) G01R 33/5608 (20130101) G01R 33/5611 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692603 | Najafi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Bijan Najafi (Tucson, Arizona); Martha Jane Mohler (Tucson, Arizona); Nima Toosizadeh (Tucson, Arizona) |
| ABSTRACT | Systems and methods are disclosed which provide a way to diagnose frailty using an upper extremity (and/or other body portions) frailty assessment. Within this method, several parameters can be calculated based on the kinematics (e.g., pure motion without including forces) and kinetics (e.g., analysis of forces and moments) of, for example, joint flexion/extension. An ordinal and/or continuous frailty score can be determined based on calculated markers of frailty, such as slowness, weakness, flexibility, and/or exhaustion, while performing a short-duration upper extremity task. Patients can be classified as non-frail, pre-frail, or frail. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711181 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692710 | Prabhakaran et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Aneesh Prabhakaran (Richland, Washington); Yehia M. Ibrahim (Richland, Washington); Sandilya V. B. Garimella (Richland, Washington) |
| ABSTRACT | A method of manipulating ions comprises injecting ions between a first surface and a second surface positioned parallel to and spaced apart from each other and defining a central axis therebetween, wherein the first surface comprises first outer electrodes coupled to the first surface and a first inner array of electrodes coupled to the first surface and positioned between the first outer electrodes, wherein the second surface comprises second outer electrodes coupled to the second surface and a second inner array of electrodes coupled to the second surface and positioned between the second outer electrodes, and applying a frequency modulated RF voltage to at least one electrode of the first inner array of electrodes or the second inner array of electrodes to confine ions between the first surface and the second surface and to guide ions between the first surface and the second surface along the central axis. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/194161 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) Original (OR) Class H01J 49/062 (20130101) H01J 49/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693206 | Bahl et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gaurav Bahl (Champaign, Illinois); Christopher Peterson (Champaign, Illinois) |
| ABSTRACT | A nonreciprocal device includes a waveguide through which waves at a first frequency propagate with a first wavevector and with a second wavevector in a direction opposite to the first wavevector; a frequency-dependent device that operates within a frequency range and modifies the waves through the waveguide in a way that is dependent on the first frequency; and a set of couplers to couple the waveguide and the frequency-dependent device. Coupling rates of the set of couplers are modulated to enable nonreciprocal coupling, with respect to the frequency-dependent device, of the first wavevector compared to the second wavevector. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/121915 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4208 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/32 (20130101) Original (OR) Class H01P 1/36 (20130101) H01P 1/38 (20130101) H01P 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693544 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Yunfei Ma (Santa Clara, California); Zhihong Luo (Cambridge, Massachusetts); Christoph Steiger (Cambridge, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | Multiple antennas of a beamformer may simultaneously transmit wireless signals at different frequencies. The signals may comprise synchronized, identical wireless commands, each at a different carrier frequency. The transmitted signals may constructively and destructively interfere with each other at a receiver antenna, to form a beat signal. When the transmitted signals constructively interfere, the beat signal may cause a voltage in the receiver to exceed a threshold voltage. The threshold voltage may be a minimum voltage at which a device, which is operatively connected to the receiver antenna, is able to perform energy harvesting or wireless communication. The beamformer may operate under blind channel conditions, because the transmitted frequencies may be selected in such a way as to maximize peak power delivered under all possible channel conditions. The beamformer may deliver wireless power to a sensor or actuator that is located deep inside bodily tissue. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 16/391740 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10217 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class H04B 13/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694123 | Cossairt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Oliver Strider Cossairt (Evanston, Illinois); Jason Holloway (Houston, Texas); Ashok Veeraraghavan (Houston, Texas); Manoj Kumar Sharma (Houston, Texas); Yicheng Wu (Houston, Texas) |
| ABSTRACT | A method for imaging objects includes illuminating an object with a light source of an imaging device, and receiving an illumination field reflected by the object. An aperture field that intercepts a pupil of the imaging device is an optical propagation of the illumination field at an aperture plane. The method includes receiving a portion of the aperture field onto a camera sensor, and receiving a sensor field of optical intensity. The method also includes iteratively centering the camera focus along the Fourier plane at different locations to produce a series of sensor fields and stitching together the sensor fields in the Fourier domain to generate an image. The method also includes determining a plurality of phase information for each sensor field in the series of sensor fields, applying the plurality of phase information to the image, receiving a plurality of illumination fields reflected by the object, and denoising the intensity of plurality of illumination fields using Fourier ptychography. |
| FILED | Saturday, July 14, 2018 |
| APPL NO | 16/035629 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 1/3216 (20130101) H04N 5/213 (20130101) H04N 5/217 (20130101) H04N 5/357 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10687795 | Sharma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arsenal Medical, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Arsenal Medical, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Upma Sharma (Somerville, Massachusetts); Rany Busold (Medford, Massachusetts); Adam Rago (Falmouth, Massachusetts); Gregory T. Zugates (Chelmsford, Massachusetts); Toby Freyman (Lexington, Massachusetts); Lisette Manrique Miller (Taunton, Massachusetts) |
| ABSTRACT | Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411505 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00491 (20130101) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00495 (20130101) A61B 2017/00544 (20130101) A61B 2017/00548 (20130101) A61B 2017/8838 (20130101) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 9/0026 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) A61M 5/1409 (20130101) A61M 5/1452 (20130101) A61M 5/16804 (20130101) A61M 13/003 (20130101) A61M 2205/103 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/04453 (20130101) B01F 5/0602 (20130101) B01F 5/0604 (20130101) B01F 7/00558 (20130101) B01F 7/00583 (20130101) B01F 13/0023 (20130101) B01F 15/00253 (20130101) B01F 15/0279 (20130101) B01F 15/00525 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/0037 (20130101) B05B 7/2421 (20130101) B05B 7/2472 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 17/00553 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 81/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688174 | Richardson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles Richardson (Cambridge, Massachusetts); Thomas S. Vedvick (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); William Tino (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429580 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5258 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688284 | Hill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Westin Michael Hill (Cambridge, Massachusetts); Matthew Roy Johnson (Somerville, Massachusetts); Tara Lee Schmidt Boettcher (Chelmsford, Massachusetts); Patrick James Codd (Boston, Massachusetts) |
| ABSTRACT | A steerable endoscopic tool uses concentric sleeves of varying curvature to steer a tool tip toward or in the direction of a location of surgical interest. By rotating and/or axially displacing such sleeves relative to one another the tool tip may be maneuvered within a current field of view with several degrees of freedom without any physical movement of an endoscope, thus facilitating improved surgical access and control without complex mechanical systems in the endoscope or at the surgical site. |
| FILED | Friday, November 21, 2014 |
| APPL NO | 14/550436 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/018 (20130101) A61B 1/0055 (20130101) A61B 1/00154 (20130101) A61B 2017/00331 (20130101) A61B 2018/00029 (20130101) A61B 2018/00339 (20130101) A61B 2018/00577 (20130101) A61B 2018/00982 (20130101) A61B 2018/2238 (20130101) A61B 2018/20361 (20170501) A61B 2218/002 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0133 (20130101) A61M 25/0136 (20130101) A61M 25/0141 (20130101) A61M 25/0147 (20130101) Original (OR) Class A61M 25/0152 (20130101) A61M 2025/015 (20130101) A61M 2025/0681 (20130101) A61M 2205/0266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689044 | Tolley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael T. Tolley (Cambridge, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Bobak Mosadegh (Boston, Massachusetts); Robert J. Wood (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A pneumatically powered, fully untethered mobile soft robot is described. Composites consisting of silicone elastomer, polyaramid fabric, and hollow glass microspheres were used to fabricate a sufficiently large soft robot to carry the miniature air compressors, battery, valves, and controller needed for autonomous operation. Fabrication techniques were developed to mold a 0.65 meter long soft body with modified Pneumatic network actuators capable of operating at the elevated pressures (up to 138 kPa) required to actuate the legs of the robot and hold payloads of up to 8 kg. The soft robot is safe to handle, and its silicone body is innately resilient to a variety of adverse environmental conditions including snow, puddles of water, direct (albeit limited) exposure to flames, and the crushing force of being run over by an automobile. |
| FILED | Tuesday, June 30, 2015 |
| APPL NO | 14/755026 |
| ART UNIT | 3611 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 18/06 (20130101) Motor Vehicles; Trailers B62D 57/02 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/09 (20130101) Y10S 901/22 (20130101) Y10S 901/27 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689284 | Gibson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel J. Gibson (Cheverly, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Guillermo R. Villalobos (Springfield, Virginia); Ishwar D. Aggarwal (Chapel Hill, North Carolina); Dean A Scribner (Arlington, Virginia) |
| ASSIGNEE(S) | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| INVENTOR(S) | Daniel J. Gibson (Cheverly, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Guillermo R. Villalobos (Springfield, Virginia); Ishwar D. Aggarwal (Chapel Hill, North Carolina); Dean A Scribner (Arlington, Virginia) |
| ABSTRACT | The present invention is directed to a method for making infrared transmitting graded index optical elements by selecting at least two different infrared-transmitting materials, each with a different refractive index, having similar thermo-viscous behavior; assembling the infrared-transmitting materials into a stack comprising one or more layers of each infrared-transmitting material resulting in the stack having a graded index profile; and forming the stack into a desired shape. Also disclosed is the related optical element made by this method. |
| FILED | Friday, February 10, 2012 |
| APPL NO | 13/370485 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 23/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689397 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Reuben J. Shaw (La Jolla, California); Daniel F. Egan (La Jolla, California); Nicholas Cosford (La Jolla, California); Benjamin Turk (New Haven, Connecticut); Mitchell Vamos (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Matthew Chun (La Jolla, California); Douglas Sheffler (La Jolla, California) |
| ABSTRACT | In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/269468 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/34 (20130101) C07D 239/42 (20130101) C07D 239/47 (20130101) C07D 239/48 (20130101) C07D 239/557 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) Original (OR) Class Peptides C07K 7/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/11001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/912 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689422 | Savarino |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stephen Savarino (Kensington, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Stephen Savarino (Kensington, Maryland) |
| ABSTRACT | The inventive subject matter relates to a recombinant polypeptide constructs comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the induction of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti-enterotoxigenic Escherichia coli immunity. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/079388 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0258 (20130101) A61K 2039/70 (20130101) A61K 2039/523 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) A61K 2039/627 (20130101) A61K 2039/55544 (20130101) Peptides C07K 14/245 (20130101) Original (OR) Class C07K 2319/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/474 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689608 | Levner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMULATE, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | EMULATE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Daniel Levner (Brookline, Massachusetts); Josiah Daniel Sliz (Boston, Massachusetts); Christopher David Hinojosa (Malden, Massachusetts); Guy Robert Thompson, II (Watertown, Massachusetts); Petrus Wilhelmus Martinus van Ruijven (Glen Waverley, Australia); Matthew Daniel Solomon (Hughesdale, Australia); Christian Alexander Potzner (Port Melbourne, Australia); Patrick Sean Tuohy (St. Kilda, Australia) |
| ABSTRACT | Drop-to-drop connection schemes are described for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/108827 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/021 (20130101) A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 9/527 (20130101) B01L 2200/12 (20130101) B01L 2200/025 (20130101) B01L 2200/027 (20130101) B01L 2300/14 (20130101) B01L 2300/123 (20130101) B01L 2300/161 (20130101) B01L 2300/165 (20130101) B01L 2300/0681 (20130101) B01L 2300/0887 (20130101) B01L 2400/06 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 23/38 (20130101) C12M 23/40 (20130101) C12M 23/42 (20130101) C12M 29/10 (20130101) C12M 35/04 (20130101) C12M 41/40 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 2521/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689642 | Townshend et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Brent Townshend (Menlo Park, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Provided herein, among other things, is an automatable procedure that employs in vitro directed evolution to create DNA sequences that encode a ligand-responsive ribozyme and which, when transcribed, can control expression of genes they are coupled to. The method also allows creation of functional RNA sequences that bind target molecules, without requiring any modification or immobilization of the target. |
| FILED | Tuesday, June 28, 2016 |
| APPL NO | 15/744718 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 15/1048 (20130101) Original (OR) Class C12N 15/1096 (20130101) C12N 2310/12 (20130101) C12N 2310/16 (20130101) C12N 2330/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689652 | Stampfer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Martha R. Stampfer (Oakland, California); James C. Garbe (San Francisco, California) |
| ABSTRACT | Methods for inducing non-clonal immortalization of normal epithelial cells by directly targeting the two main senescence barriers encountered by cultured epithelial cells. In finite lifespan pre-stasis human mammary epithelial cells (HMEC), the stress-associated stasis barrier was bypassed, and in post-stasis HMEC, the replicative senescence barrier, a consequence of critically shortened telomeres, was bypassed. Early passage non-clonal immortalized lines exhibited normal karyotypes. Methods of efficient HMEC immortalization, in the absence of “passenger” genomic errors, should facilitate examination of telomerase regulation and immortalization during human carcinoma progression, methods for screening for toxic and environmental effect on progression, and the development of therapeutics targeting the process of immortalization. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/256395 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) C12N 5/0693 (20130101) C12N 15/62 (20130101) C12N 15/1136 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2501/606 (20130101) C12N 2510/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5014 (20130101) G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689654 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Hong Yan Liu (Martinez, Georgia) |
| ABSTRACT | A bivalent siRNA chimera platform capable of efficiently delivering and silencing two or more genes in vivo or in vitro is provided. Methods of using the bivalent siRNA chimeras for selectively targeting cells to down-regulate the expression of multiple genes are also provided. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 15/726851 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 47/549 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/322 (20130101) C12N 2310/344 (20130101) C12N 2310/3519 (20130101) C12N 2310/3533 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689701 | Tsalik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Ephraim Tsalik (Durham, North Carolina); Vance Fowler (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Joseph E. Lucas (Chapel Hill, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Sun Hee Ahn (Gwangju, South Korea) |
| ABSTRACT | Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/214853 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689764 | Angeli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Robert J Angeli (Portsmouth, Rhode Island) |
| ABSTRACT | A mounting bolt and sacrificial anode assembly is provided. The zinc anode is cylindrical while the mounting bolt is made from aluminum alloy and is machine threaded with an anodized bolt head resting on an anodized bolt head shoulder having two faces with one face being non-anodized. For assembly, the anode is heated to a uniform temperature of approximately two hundred degrees Fahrenheit and the mounting bolt is cooled to approximately zero degrees Fahrenheit after a minimum of six hours and preferably twenty-four hours. The anode is then hand pressed onto the mounting bolt to bottom out on the non-anodized face in order to form a single fused assembly. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/901917 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 13/10 (20130101) Original (OR) Class C23F 2213/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689988 | Gautschi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Steven Bruce Gautschi (Naugatuck, Connecticut); San Quach (East Hartford, Connecticut); Tracy A Propheter-Hinckley (Manchester, Connecticut) |
| ABSTRACT | A component for a gas turbine engine includes a root with a neck that extends into a fir tree with at least one tooth, the root includes a feed passage in communication with a multiple of cooling passages that extend through the neck and fir tree. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/683408 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/082 (20130101) F01D 5/3007 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690340 | Roychoudhury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Subir Roychoudhury (Madison, Connecticut); Richard T. Mastanduno (Milford, Connecticut); Bruce Crowder (North Haven, Connecticut); Benjamin D. Baird (Rocky Hill, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Subir Roychoudhury (Madison, Connecticut); Richard T. Mastanduno (Milford, Connecticut); Bruce Crowder (North Haven, Connecticut); Benjamin D. Baird (Rocky Hill, Connecticut) |
| ABSTRACT | A flameless cooking apparatus for use with liquid fuels and for indoor or outdoor use under field operations. The burner exhibits low CO and hydrocarbon emissions and meets standards for burner thermal efficiency when used with JP-8 fuel. The apparatus employs a catalytic burner having among its parts (i) a combustion catalyst; (ii) a conductive surface, e.g., cooking surface; and (iii) in between the catalyst and the conductive surface and in direct physical contact with both surfaces, a heat spreader for conductively transferring heat of combustion from the catalyst to the conductive surface. Also claimed are a method of heat flux and a method of cooking. |
| FILED | Wednesday, January 06, 2010 |
| APPL NO | 12/655703 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 13/08 (20130101) Burners F23D 11/40 (20130101) F23D 14/18 (20130101) Original (OR) Class F23D 2212/20 (20130101) F23D 2214/00 (20130101) Domestic Stoves or Ranges; Details of Domestic Stoves or Ranges, of General Application F24C 3/067 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 40/166 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/342 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690459 | Sherlock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mary H. Sherlock (Waldorf, Maryland); Brian A. Cole (King George, Virginia); Kyle M. Beckett (Pomfret, Maryland); Joshua E. Felts (Indian Head, Maryland); Forrest R. Svingala (Los Alamos, New Mexico); Reid M. McKeown (Clarksville, Maryland); Harold W. Sandusky (Fulton, Maryland) |
| ABSTRACT | A fuze booster includes a first explosive charge having a cavity with an annular portion of the first explosive charge encircling a first axial portion of the cavity and a semi-annular portion partially encircling a second axial portion of the cavity. The annular portion abuts the semi-annular portion. An explosively-inert material abuts the semi-annular portion, abuts the annular portion, and partially encircles the second axial portion of the cavity. A second explosive charge abuts the explosively-inert material, abuts the semi-annular portion, and partially encircles the second axial portion of the cavity. The second axial portion of the cavity is thus completely encircled by a combination of the semi-annular portion, the explosively-inert material, and the second explosive charge. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/932603 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/024 (20130101) F42B 1/032 (20130101) F42B 3/22 (20130101) Original (OR) Class Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/09 (20130101) F42C 19/0807 (20130101) F42C 19/0823 (20130101) F42C 19/0838 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690489 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Mohit Gupta (New York, New York); Shree K. Nayar (New York, New York) |
| ABSTRACT | Systems, methods, and media for performing shape measurement are provided. In some embodiments, systems for performing shape measurement are provided, the systems comprising: a projector that projects onto a scene a plurality of illumination patterns, wherein each of the illumination patterns has a given frequency, each of the illumination patterns is projected onto the scene during a separate period of time, three different illumination patterns are projected with a first given frequency, and only one or two different illumination patterns are projected with a second given frequency; a camera that detects an image of the scene during each of the plurality of periods of time; and a hardware processor that is configured to: determine the given frequencies of the plurality of illumination patterns; and measure a shape of an object in the scene. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/853246 |
| ART UNIT | 2483 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/254 (20130101) G01B 11/2536 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4661 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690528 | Ledden |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SFC Fluidics, Inc. (Fayetteville, Arkansas) |
| ASSIGNEE(S) | SFC FLUIDICS, INC. (Fayetteville, Arkansas) |
| INVENTOR(S) | Bradley Thomas Ledden (Fayetteville, Arkansas) |
| ABSTRACT | An electrochemical sensor may measure the flow of ions and/or electrochemical species in a solution passing the sensor because the electroactive species will continually come into contact with the electrode and an electric signal will be generated by the combination of diffusion and convection bringing the electroactive species to the electrode. The electric signal measured will vary by concentration of ions and/or electrochemical specie(s) and by flow rate. Flow rate may be measured if the concentration of ions and/or electrochemical specie(s) is known; conversely, the concentration of ions and/or electrochemical species may be measured if the flow rate is known. The sensor may also be used to confirm the delivery of a fluid containing ions and/or electrochemical specie(s). |
| FILED | Wednesday, October 12, 2016 |
| APPL NO | 15/765867 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1468 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/64 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/403 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690544 | Mitchell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAVEFRONT RESEARCH, INC. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Nazareth, Pennsylvania) |
| ABSTRACT | Reflective imager sub-systems that have a non-circular entrance pupil and provide substantially increased throughput to a detecting component of a system are disclosed. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/162882 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/2823 (20130101) G01J 2003/2826 (20130101) Optical Elements, Systems, or Apparatus G02B 17/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690723 | Bose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Schuyler Eldridge (Ossining, New York); Karthik V. Swaminathan (Mount Kisco, New York); Yazhou Zu (Austin, Texas) |
| ABSTRACT | Techniques facilitating determination and correction of physical circuit event related errors of a hardware design are provided. A system can comprise a memory that stores computer executable components and a processor that executes computer executable components stored in the memory. The computer executable components can comprise a simulation component that injects a fault into a latch and a combination of logic of an emulated hardware design. The fault can be a biased fault injection that can mimic an error caused by a physical circuit event error vulnerability. The computer executable components can also comprise an observation component that determines one or more paths of the emulated hardware design that are vulnerable to physical circuit event related errors based on the biased fault injection. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/398972 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31704 (20130101) G01R 31/318357 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/00 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690766 | Miranda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Analee M Miranda (Troy, New York); Loria L Wang (Beavercreek, Ohio); Stephanie R Keith (Charlottesvulle, Virginia) |
| ABSTRACT | A wideband RADAR system and method is provided for biometric identification and authentication of a human subject. The system includes a source of wideband RADAR signals, an amplifier, and a splitter in electrical communication with the source of wideband RADAR signals and configures to split a generated signal into a transmit signal and a reference transmit signal. A transmitting antenna is configured to transmit the transmit signal from the splitter toward a turntable configured to rotate the human subject. A receiving antenna is configured to receive transmitted signals reflected from the human subject. A controller is configured to process the received reflected signals and generate polar representations of biometric radar signature features to compare against known signatures of human subjects. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913335 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/18 (20130101) A61B 5/1075 (20130101) A61B 5/4504 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/412 (20130101) G01S 7/414 (20130101) G01S 7/2813 (20130101) G01S 13/89 (20130101) Original (OR) Class G01S 13/0209 (20130101) G01S 2007/2886 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690767 | Hansen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Charles T. Hansen (Palos Verdes Estates, California) |
| ABSTRACT | A system and method for forming synthetic aperture radar images. Radar return pulses are grouped into sub-dwells, and their frequency content is separated into frequency sub-bands. A coarse image is formed for each sub-band/sub-dwell combination. The coarse images are iteratively interpolated to higher resolution and combined, to form a single high-resolution synthetic aperture radar image. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/838053 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/90 (20130101) Original (OR) Class G01S 13/904 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690809 | Kamali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seyedeh Mahsa Kamali (Arcadia, California); Ehsan Arbabi (Arcadia, California); Amir Arbabi (Sunderland, Massachusetts); Yu Horie (Pasadena, California); MohammadSadegh Faraji-Dana (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | A metasurface is defined by an array of scattering elements having a U shape, where the geometrical dimensions determining the U shape are determined according to the different phase profiles that the metasurface is meant to generate in response to an incident electromagnetic wave. The metasurface, therefore, generates different phase shifts as a function of the incident electromagnetic wave. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125546 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class G02B 1/02 (20130101) G02B 5/0294 (20130101) G02B 5/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690817 | Shalaev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vladimir Shalaev (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Xingjie Ni (Albany, California); Satoshi Ishii (Hyogo, Japan) |
| ABSTRACT | An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000843 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/834 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690856 | Bahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Gaurav Bahl (Champaign, Illinois); Donggyu Benjamin Sohn (Urbana, Illinois) |
| ABSTRACT | Systems and methods provide a nonreciprocal nanophotonic modulator. In some examples, the modulator utilizes acoustic pumping, instead of optical pumping with lasers, and is capable of achieving GHz bandwidth. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259775 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2746 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/125 (20130101) G02F 1/0126 (20130101) G02F 1/0134 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690865 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | AIRBORN INC. (Georgetown, Texas) |
| INVENTOR(S) | Lance A. Wood (Winter Park, Colorado); Harsha Krishna Kopuru (Parker, Colorado); Rebekah Jean Mitchell (Littleton, Colorado); Jason Paul Smith (Sartell, Minnesota); Timothy John Wasland (Little Falls, Minnesota) |
| ABSTRACT | A space active optical cable (SAOC) includes a cable including one or more optical fibers, and two or more electrical transceivers on opposing ends of the cable and interconnected by the cable. Each of the electrical transceivers includes an enclosure that encloses one or more light sources, one or more light detectors, and control electronics. Also included in the enclosure are a coupling medium to couple light into and out of the one or more optical fibers. The coupling medium can be reflecting surface or an on-axis mount. The enclosure provides a suitable heat propagation and electromagnetic interference (EMI) shielding, and the cable and the two or more electrical transceivers are radiation resistant. SAOC features optionally support a health check algorithm that allows trending optical performance in the absence of an optical connector and a potential surface treatment to increase nominally low emissivity of an EMI conductive surface. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/581560 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/428 (20130101) G02B 6/4206 (20130101) G02B 6/4214 (20130101) G02B 6/4246 (20130101) Original (OR) Class G02B 6/4267 (20130101) G02B 6/4277 (20130101) G02B 6/4284 (20130101) G02B 6/4286 (20130101) G02B 6/4415 (20130101) Transmission H04B 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690876 | Jungwirth |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Matthew Edward Lewis Jungwirth (Golden Valley, Minnesota) |
| ABSTRACT | An optical image tracker is disclosed. The optical image tracker includes a multi-dimensional translation stage. An optical image detector is disposed on a surface of the multi-dimensional translation stage. An objective lens is coupled to the optical image detector and configured to focus a collimated beam of light on the optical image detector, wherein the collimated beam of light includes a specific field of view within a field of regard, and the multi-dimensional translation stage is configured to position the optical image detector to detect the collimated beam of light. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 15/713487 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/02 (20130101) G01C 21/025 (20130101) Optical Elements, Systems, or Apparatus G02B 7/005 (20130101) Original (OR) Class G02B 13/16 (20130101) G02B 27/64 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690933 | Furstenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert Furstenberg (Burke, Virginia); Chris Kendziora (Burke, Virginia); R. Andrew McGill (Lorton, Virginia) |
| ABSTRACT | A speckle reduction instrument having a parabolic reflector and flat mirror to form a cavity-based unit. Laser light is collected and bounced around the cavity hitting a diffuser surface multiple times. The laser light that is highly coherent is converted into less-coherent but still bright light suitable for illumination in microscopes and other devices. Also disclosed is the related method for reducing speckle. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/946858 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0284 (20130101) G02B 27/48 (20130101) Original (OR) Class G02B 27/0983 (20130101) G02B 27/0994 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690992 | Frantz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia); Robel Y. Bekele (Washington, District of Columbia); Christopher M. Spillmann (Annandale, Virginia); Jawad Naciri (Herndon, Virginia); Jakub Kolacz (Washington, District of Columbia); Henry G. Gotjen (Washinton, District of Columbia); Jason Auxier (Falls Church, Virginia); Leslie Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | A method for making a chalcogenide glass waveguide in a liquid crystal-based non-mechanical beam steering device that permits steering in the mid-wave infrared. The waveguide core, the subcladding, or both comprise a chalcogenide glass. A mask is used to produce a tapered subcladding. Also disclosed is the related non-mechanical beam steering device that includes a chalcogenide waveguide. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946011 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 13/043 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/0018 (20130101) G02F 1/292 (20130101) Original (OR) Class G02F 1/1326 (20130101) G02F 1/1337 (20130101) G02F 1/2955 (20130101) G02F 1/134309 (20130101) G02F 2001/0113 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691154 | Hoffmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Heiko Hoffmann (Simi Valley, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | Described is a system for decreasing the frequency of large cascading failures in a transmission network. Based on sensors distributed throughout the transmission network, the system determines if a cascading failure is present in a transmission network. Following determination of the cascading failure, the system activates at least one switch of a plurality of switches distributed in the transmission network in order to switch transmission lines, thereby altering connectivity in the transmission network. |
| FILED | Tuesday, April 25, 2017 |
| APPL NO | 15/496791 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/086 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691282 | Nogin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Aleksey Nogin (Fresno, California); Michael A. Warren (Northridge, California); Gavin D. Holland (Newbury Park, California) |
| ABSTRACT | Described is a high-assurance network gateway generator that generates and encodes network gateway code on a computer readable medium. In operation, the network gateway generator receives input artifacts, which are translated into corresponding formats as translated data. The translated data is distributed to an OS code generator, a glue code generator, and a communications code generator. The OS code generator then generates OS code based on the translated data. The communications code generator proceeds to generate deserialization and filtering code based on the translated data. Further, a glue code generator generates glue code based on the OS code and translated data. An executable network gateway code is then generated by combining the glue code, deserialization code, and filtering code. Finally, the executable network gateway code is then encoded on a computer readable medium. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/034244 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) Original (OR) Class G06F 40/174 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691743 | Sawhney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Harpreet Singh Sawhney (Princeton Junction, New Jersey); Jayakrishnan Eledath (Robbinsville, New Jersey); Mayank Bansal (Lawrenceville, New Jersey); Bogdan C. Matei (Princeton Junction, New Jersey); Xutao Lv (East Windsor, New Jersey); Chaitanya Desai (Lawrenceville, New Jersey); Timothy Shields (Lumberton, New Jersey) |
| ABSTRACT | A computing system for realizing visual content of an image collection executes feature detection algorithms and semantic reasoning techniques on the images in the collection to elicit a number of different types of visual features of the images. The computing system indexes the visual features and provides technologies for multi-dimensional content-based clustering, searching, and iterative exploration of the image collection using the visual features and/or the visual feature indices. |
| FILED | Tuesday, August 05, 2014 |
| APPL NO | 14/452237 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/50 (20190101) Original (OR) Class G06F 16/5838 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00684 (20130101) G06K 9/6224 (20130101) G06K 2209/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691843 | Estee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OMC2 LLC (Berkeley, California) |
| ASSIGNEE(S) | OMC2 LLC (Berkeley, California) |
| INVENTOR(S) | Michael Estee (Oakland, California); Forrest Green (Austin, Texas); Thomas Cauchois (Berkeley, California); Sarah Tappon (Oakland, California) |
| ABSTRACT | A method of rendering a machine state, a method of generating and rendering a work-piece cut path, and a CNC machines system are disclosed. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/038016 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/414 (20130101) G05B 19/40937 (20130101) G05B 2219/33099 (20130101) G05B 2219/36268 (20130101) G05B 2219/36284 (20130101) Electric Digital Data Processing G06F 30/00 (20200101) Original (OR) Class G06F 2119/18 (20200101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/265 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692211 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Mehdi Alilou (Cleveland, Ohio) |
| ABSTRACT | Embodiments classify lung nodules by accessing a 3D radiological image of a region of tissue, the 3D image including a plurality of voxels and slices, a slice having a thickness; segmenting the nodule represented in the 3D image across contiguous slices, the nodule having a 3D volume and 3D interface, where the 3D interface includes an interface voxel; partitioning the 3D interface into a plurality of nested shells, a nested shell including a plurality of 2D slices, a 2D slice including a boundary pixel; extracting a set of intra-perinodular textural transition (Ipris) features from the 2D slices based on a normal of a boundary pixel of the 2D slices; providing the Ipris features to a machine learning classifier which computes a probability that the nodule is malignant, based, at least in part, on the set of Ipris features; and generating a classification of the nodule based on the probability. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/012937 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6261 (20130101) G06K 9/6269 (20130101) G06K 2209/053 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 7/194 (20170101) G06T 15/08 (20130101) G06T 2207/10081 (20130101) G06T 2207/10104 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20152 (20130101) G06T 2207/30064 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 20/40 (20180101) G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692395 | Mackenzie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Colin F. Mackenzie (Pasadena, Maryland); Shiming Yang (Halethorpe, Maryland); Fu-Ming Hu (Ellicott City, Maryland); Evan Garofalo (Phoenix, Arizona) |
| ABSTRACT | Techniques for automated surgeon performance evaluation include dressing an operator with colored surgical gloves. A first glove for a dominant hand has a first color and a second glove for the other hand has a different second color. Video data that views the operator's hands is captured during a surgical procedure on a subject. For each of multiple frames of the video data, a minimum rectangle of pixels, called a first rectangle, which encloses pixels having the first color, is determined automatically on a processor. A first time series for a representative property of the first rectangle at the multiple frames, and a first measure of entropy based on the first time series, are also automatically determined on a processor. A metric of operator performance based at least in part on the first measure of entropy is stored, e.g., for subsequent display. |
| FILED | Wednesday, August 17, 2016 |
| APPL NO | 15/753337 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 16/00 (20130101) A61B 17/00 (20130101) A61B 42/10 (20160201) A61B 90/92 (20160201) A61B 90/361 (20160201) A61B 2560/0223 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00355 (20130101) G06K 9/00744 (20130101) G06K 9/4642 (20130101) G06K 9/4652 (20130101) Image Data Processing or Generation, in General G06T 7/248 (20170101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/20021 (20130101) G06T 2207/30196 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 5/04 (20130101) G09B 19/003 (20130101) Original (OR) Class G09B 23/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692659 | Cordova |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADA Technologies, Inc. (Littleton, Colorado) |
| ASSIGNEE(S) | ADA Technologies, Inc. (Littleton, Colorado) |
| INVENTOR(S) | Stephen Cordova (Colorado Springs, Colorado) |
| ABSTRACT | An electrolyte is introduced into an electrochemical device, passed, via a first corrugation feature, through a first electrode of the electrochemical device, passed through an ion permeable separator, and contacted with a second electrode. The first or second electrode comprises a second corrugation feature in fluid communication with the first corrugation feature to contact the electrolyte across a portion of an active surface of the first or second electrode. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/224168 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/10 (20130101) Original (OR) Class H01G 11/12 (20130101) H01G 11/26 (20130101) H01G 11/50 (20130101) H01G 11/52 (20130101) H01G 11/58 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/361 (20130101) H01M 2/362 (20130101) H01M 4/13 (20130101) H01M 10/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692892 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph Smith (Tempe, Arizona); Rita Bottesch (Mesa, Arizona); John Stowell (Tempe, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Joseph Smith (Tempe, Arizona); Rita Bottesch (Mesa, Arizona); John Stowell (Tempe, Arizona) |
| ABSTRACT | Some embodiments include an imaging system. The imaging system can comprise: a scintillator structure; and an electronic device engaged with the scintillator structure, wherein: the scintillator structure can comprise: a scintillator support layer; and a scintillator layer; the scintillator support layer can comprise: a first substantially non-planar surface; and a second substantially non-planar surface, the first substantially non-planar surface can be approximately parallel to the second substantially non-planar surface; the electronic device can comprise a device substrate and one or more active sections; the device substrate can comprise a first surface and a second surface opposite the first surface of the device substrate; the one or more active sections are at the second surface of the device substrate; and the second surface of the device substrate and the one or more active sections can conform to the second surface of the scintillator layer. Other embodiments are described herein. |
| FILED | Monday, October 14, 2019 |
| APPL NO | 16/601411 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2562/02 (20130101) A61B 2562/164 (20130101) Measurement of Nuclear or X-radiation G01T 1/2018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/768 (20130101) H01L 21/6835 (20130101) H01L 21/30604 (20130101) H01L 23/15 (20130101) H01L 23/3192 (20130101) H01L 23/4985 (20130101) H01L 27/153 (20130101) H01L 27/1218 (20130101) Original (OR) Class H01L 27/1262 (20130101) H01L 27/14603 (20130101) H01L 27/14636 (20130101) H01L 27/14663 (20130101) H01L 29/78603 (20130101) H01L 33/0079 (20130101) H01L 2221/6835 (20130101) H01L 2221/68381 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692996 | Glavin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas R. Glavin (Springboro, Ohio); Kelson D. Chabak (Springboro, Ohio); Michael R. Snure (Dayton, Ohio) |
| ABSTRACT | Systems, methods and apparatus incorporating Gallium Nitride heterostructure (Alx,Iny)Ga1-x-y N-materials in flexible, strainable and wearable radio frequency devices. These devices include (Alx,Iny)Ga1-x-y N-based high-electron mobility transistors (HEMTs), which enable amplification of microwave radio frequencies from approximately 300 MHz to approximately 300 GHz for flexible and conformal wireless transmission. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266245 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 29/205 (20130101) H01L 29/778 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693029 | Cho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Benjamin Cho (Albuquerque, New Mexico); Yong Lin (Albuquerque, New Mexico); Pravin Patel (Albuquerque, New Mexico); Mark Stan (Albuquerque, New Mexico); Arthur Cornfeld (Sandy Springs, Georgia); Daniel McGlynn (Albuquerque, New Mexico); Fred Newman (Seattle, Washington) |
| ABSTRACT | A method of forming a multijunction solar cell comprising at least a first subcell and a second subcell, the method including forming a first alpha layer over said first solar subcell using a surfactant and dopant including selenium or tellurium, the first alpha layer configured to prevent threading dislocations from propagating; forming a metamorphic grading interlayer over and directly adjacent to said first alpha layer; forming a second alpha layer using a surfactant and dopant including selenium or tellurium over and directly adjacent to said grading interlayer to prevent threading dislocations from propagating; and forming the second solar subcell over said grading interlayer such that the second solar subcell is lattice mismatched with respect to the first solar subcell. |
| FILED | Wednesday, March 08, 2017 |
| APPL NO | 15/453578 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/065 (20130101) H01L 31/078 (20130101) H01L 31/184 (20130101) H01L 31/1844 (20130101) H01L 31/06875 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693071 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yang Yang (Los Angeles, California); Jingbi You (Los Angeles, California); Lei Meng (Los Angeles, California) |
| ABSTRACT | An opto-electronic device includes a first electrode, a first buffer layer formed on the first electrode, and a perovskite semiconductor active layer formed on the first buffer layer. The opto-electronic device further includes a second buffer layer formed on the perovskite semiconductor active layer, and a second electrode formed on the second buffer layer. The first buffer layer, the second buffer layer, and the perovskite semiconductor active layer each consists essentially of inorganic materials. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/553483 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0032 (20130101) Original (OR) Class H01L 51/0037 (20130101) H01L 51/422 (20130101) H01L 51/4233 (20130101) H01L 51/4246 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693165 | Higgins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Hawai'i (Honolulu, Hawaii) |
| ASSIGNEE(S) | University of Hawai'i (Honolulu, Hawaii) |
| INVENTOR(S) | Scott Robert Higgins (Honolulu, Hawaii); James Michel Ewan (Cypress, Texas) |
| ABSTRACT | In one embodiment, an environmental sensor array monitors pre-filter airflow to a fuel cell with an air filter, and senses amounts of filter exposure of air contaminants in the monitored pre-filter airflow. The environmental sensor array may then correlate the sensed amounts of filter exposure over time to a long-term adsorption limit of the air contaminants for the air filter, determining a lifetime usage level of the air filter. Accordingly, the environmental sensor array may provide an indication of the lifetime usage level of the air filter. In another embodiment, the environmental sensor array may also monitor post-filter airflow to the fuel cell, and senses instantaneous levels of post-filter air contaminants. In response to the instantaneous level of any particular air contaminant of the post-filter air contaminants being above a respective threshold level, the environmental sensor array may protect the operation of the fuel cell (e.g., de-rate, shut down, etc.). |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/269390 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04955 (20130101) Original (OR) Class H01M 8/04992 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693178 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jitendra Kumar (Centerville, Ohio); Priyanka Bhattacharya (Beavercreek, Ohio); Guru Subramanyam (Dayton, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF DAYTON (Dayton, Ohio) |
| INVENTOR(S) | Jitendra Kumar (Centerville, Ohio); Priyanka Bhattacharya (Beavercreek, Ohio); Guru Subramanyam (Dayton, Ohio) |
| ABSTRACT | Lithium sulfur batteries are described, especially ones that are flexible for wearing about an appendage of a wearer. Such batteries have a lithium metal anode, a sulfur cathode comprising sulfur, a conductive carbon, a lithium supertonic solid-state conductor, and a dendritic or hyperbranched polymer binder, an electrolyte layer between the lithium metal anode and the sulfur cathode, and a current collector positioned on the sulfur cathode opposite the electrolyte layer. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956043 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/382 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/626 (20130101) H01M 4/663 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 10/0436 (20130101) H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2220/30 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693201 | Smoot et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ThermAvant Technologies, LLC (Columbia, Missouri) |
| ASSIGNEE(S) | ThermAvant Technologies, LLC (Columbia, Missouri) |
| INVENTOR(S) | Christopher D. Smoot (Columbia, Missouri); Joe Boswell (San Francisco, California); Corey A. Wilson (Jefferson City, Missouri) |
| ABSTRACT | A thermal management system for the at least one energy cell. The thermal management system includes a cold plate cell holder comprising at least one energy cell reservoir structured to retain the energy cell(s) and surround at least a first portion of a surface of the energy cell(s), and to thermally cool the energy cell(s). The system additionally includes a bus bar header to which one or more bus bar can be physically and thermally connected, and at least one oscillating heat pipe (OHP) cover disposable around a second portion of the surface of the energy cell(s). The OHP cover(s) is/are thermally and mechanically connectable to the cold plate cell holder when disposed around the energy cell(s). The OHP cover(s) is/are structured and operable to thermally cool the energy cell(s) via heat absorption from the second portion of the surface of the energy cell(s) when disposed around the energy cell(s). |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840708 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/206 (20130101) H01M 10/613 (20150401) H01M 10/625 (20150401) H01M 10/643 (20150401) H01M 10/6552 (20150401) Original (OR) Class H01M 10/6555 (20150401) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693206 | Bahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gaurav Bahl (Champaign, Illinois); Christopher Peterson (Champaign, Illinois) |
| ABSTRACT | A nonreciprocal device includes a waveguide through which waves at a first frequency propagate with a first wavevector and with a second wavevector in a direction opposite to the first wavevector; a frequency-dependent device that operates within a frequency range and modifies the waves through the waveguide in a way that is dependent on the first frequency; and a set of couplers to couple the waveguide and the frequency-dependent device. Coupling rates of the set of couplers are modulated to enable nonreciprocal coupling, with respect to the frequency-dependent device, of the first wavevector compared to the second wavevector. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/121915 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4208 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/32 (20130101) Original (OR) Class H01P 1/36 (20130101) H01P 1/38 (20130101) H01P 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693235 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Shuguang Chen (Bel Air, Maryland) |
| ABSTRACT | Various embodiments are described that relate to patch antenna elements and parasitic feed pads. A patch antenna element can have a resistance and reactance. The resistance can be desirable while the reactance can be undesirable. To counteract the reactance, a parasitic feed pad can be placed near the patch antenna element and the parasitic feed pad produces a capacitance. The capacitance balances out the reactance to cancel out one another. When two patch antenna elements and two parasitic feed elements are employed in one antenna stack, the stack antenna can function as a dual band antenna. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/869166 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/045 (20130101) Original (OR) Class H01Q 9/0414 (20130101) H01Q 21/08 (20130101) H01Q 21/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693298 | Brockschmidt, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Arthur Brockschmidt, Jr. (Chicago, Illinois); Tina Stoia (Chicago, Illinois); Shailesh Atreya (Chicago, Illinois) |
| ABSTRACT | Example methods and systems described herein include periodically adjusting load applied to a power generating device according to a testing cycle, detecting a peak power point of the power generating device and an associated load that results in the peak power point, adjusting the load applied to the power generating device to match the associated load that results in the peak power point, and based on the adjusted load drawing power outside of a threshold amount of the peak power point, (i) calculating a correction factor to apply to a reference voltage of the power generating device and (ii) adjusting a frequency of the testing cycle. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023000 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 8/003 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/12 (20130101) H02J 3/385 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693524 | Bahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Gaurav Bahl (Champaign, Illinois); Sameh Tawfick (Champaign, Illinois); Rhinithaa P Thanalakshme (Urbana, Illinois); Ali Kanj (Urbana, Illinois); Inbar Grinberg (Urbana, Illinois); Jennifer Bernhard (Urbana, Illinois) |
| ABSTRACT | The present disclosure provides a device and method for producing low-frequency magnetic-field signals to enable long-range wireless communication through conductive media. The magnetic-field signals can be generated by mechanically moving permanent magnets. In some examples, transmitters are capable of transmitting signals in the ultra-low and very-low frequency ranges (e.g., 100 Hz-30 kHz), utilizing a small amount of power. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/352090 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Dynamo-electric Machines H02K 1/2706 (20130101) Transmission H04B 5/0031 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693565 | Kirby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brian T. Kirby (Baltimore, Maryland); Daniel E. Jones (Middle River, Maryland); Michael Brodsky (Millburn, New Jersey) |
| ABSTRACT | Methods and apparatuses are provided that compensate for the polarization dependent loss (PDL) of fiber-optic quantum channels. Compensation is accomplished by inserting a compensating PDL into another quantum channel carrying entangled photons that are entangled with photons in the first channel having losses that are to be compensated for. By selecting the optimum magnitude and orientation for the compensating PDL, compensation for the PDL in the first channel is maximized. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571640 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Transmission H04B 10/70 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693566 | Sliwa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Katrina Sliwa (New Haven, Connecticut); Michael Hatridge (New Haven, Connecticut); Anirudh Narla (New Haven, Connecticut); Shyam Shankar (New Haven, Connecticut); Luigi Frunzio (North Haven, Connecticut); Robert J. Schoelkopf, III (Madison, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | A wireless Josephson-junction-based parametric converter is described. The converter may be formed on a substrate with antennas that pump are configured to wirelessly receive pump, signal and idler frequencies and couple the received frequencies to the converter's circuitry. Capacitors may also be fabricated on the same substrate and sized to tune operation of the converter to desired frequencies. The converter may be coupled directly to microwave waveguides, and may be tuned to different signal frequencies by applying magnetic flux to the converter circuitry. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/567198 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/025 (20130101) H01L 39/045 (20130101) H01L 39/223 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/12 (20130101) H01P 5/08 (20130101) H01P 5/024 (20130101) H01P 5/103 (20130101) Demodulation or Transference of Modulation From One Carrier to Another H03D 7/005 (20130101) H03D 2009/0691 (20130101) Amplifiers H03F 19/00 (20130101) Transmission H04B 10/70 (20130101) H04B 10/90 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693582 | Rosasco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Richard J. Rosasco (Millersville, Maryland); Brian W. Stevens (Elkridge, Maryland); Aaron T. Thomas (Middletown, Maryland) |
| ABSTRACT | An example method for determining a physical cell identifier is provided. The example method may include receiving a first and second signal captures from wireless, cellular communication signals transmitted by a base station. The first signal capture being a portion of a first radio frame and the second signal capture being a portion of a second, subsequent radio frame. The method may further include aligning the first and second signal captures to determine a location of a start of a first symbol in each and decoding data within signal captures to generate a first capture grid and a second capture grid. The method may further include combining the capture grids into a resultant grid and determining a subset of possible physical cell identifiers based on a position of a selected reference symbol within the resultant grid to assist with determining a current cell identifier. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233148 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Multiplex Communication H04J 11/0069 (20130101) Original (OR) Class H04J 11/0079 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) H04L 5/0078 (20130101) H04L 5/0094 (20130101) H04L 27/2607 (20130101) Wireless Communication Networks H04W 56/001 (20130101) H04W 72/0446 (20130101) H04W 76/11 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693787 | Schneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Timo Schneider (Zurich, Switzerland); Keith D. Underwood (Powell, Tennessee); Mario Flajslik (Hopkinton, Massachusetts); Sayantan Sur (Portland, Oregon); James Dinan (Hudson, Massachusetts) |
| ABSTRACT | Techniques are disclosed to throttle bandwidth imbalanced data transfers. In some examples, an example computer-implemented method may include splitting a payload of a data transfer operation over a network fabric into multiple chunk get operations, starting the execution of a threshold number of the chunk get operations, and scheduling the remaining chunk get operations for subsequent execution. The method may also include executing a scheduled chunk get operation in response determining a completion of an executing chunk get operation. In some embodiments, the chunk get operations may be implemented as triggered operations. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686264 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/10 (20130101) Original (OR) Class H04L 47/125 (20130101) H04L 49/3072 (20130101) H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693818 | Underwood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | Keith D. Underwood (Powell, Tennessee); Charles A. Giefer (Seattle, Washington) |
| ABSTRACT | Packet tracking techniques for communication networks are described. In an example embodiment, an apparatus may comprise circuitry, a tracking component for execution by the circuitry to, in response to a request of an initiator device to establish a packet transfer session, determine whether tracking information for the packet transfer session can be locally maintained and in response to a determination that the tracking information for the packet transfer session cannot be locally maintained, identify one or more tracking parameters for retention at the initiator device, and a communication component for execution by the circuitry to send an acceptance message to grant the request of the initiator device to establish the packet transfer session, the acceptance message to indicate a request for retention of the one or more tracking parameters. Other embodiments are described and claimed. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189323 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 49/9057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694122 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael W. Kelly (North Reading, Massachusetts); Megan H. Blackwell (Boston, Massachusetts); Curtis B. Colonero (Shrewsbury, Massachusetts); James Wey (Arlington, Massachusetts); Christopher David (Chelmsford, Massachusetts); Justin Baker (North Andover, Massachusetts); Joseph Costa (Bedford, Massachusetts) |
| ABSTRACT | When imaging bright objects, a conventional detector array can saturate, making it difficult to produce an image with a dynamic range that equals the scene's dynamic range. Conversely, a digital focal plane array (DFPA) with one or more m-bit counters can produce an image whose dynamic range is greater than the native dynamic range. In one example, the DFPA acquires a first image over a relatively brief integration period at a relatively low gain setting. The DFPA then acquires a second image over longer integration period and/or a higher gain setting. During this second integration period, counters may roll over, possibly several times, to capture a residue modulus 2m of the number of counts (as opposed to the actual number of counts). A processor in or coupled to the DFPA generates a high-dynamic range image based on the first image and the residues modulus 2m. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103366 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/355 (20130101) H04N 5/2355 (20130101) H04N 5/23254 (20130101) H04N 5/23267 (20130101) H04N 5/35572 (20130101) H04N 5/35581 (20130101) Original (OR) Class H04N 5/37455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694123 | Cossairt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Oliver Strider Cossairt (Evanston, Illinois); Jason Holloway (Houston, Texas); Ashok Veeraraghavan (Houston, Texas); Manoj Kumar Sharma (Houston, Texas); Yicheng Wu (Houston, Texas) |
| ABSTRACT | A method for imaging objects includes illuminating an object with a light source of an imaging device, and receiving an illumination field reflected by the object. An aperture field that intercepts a pupil of the imaging device is an optical propagation of the illumination field at an aperture plane. The method includes receiving a portion of the aperture field onto a camera sensor, and receiving a sensor field of optical intensity. The method also includes iteratively centering the camera focus along the Fourier plane at different locations to produce a series of sensor fields and stitching together the sensor fields in the Fourier domain to generate an image. The method also includes determining a plurality of phase information for each sensor field in the series of sensor fields, applying the plurality of phase information to the image, receiving a plurality of illumination fields reflected by the object, and denoising the intensity of plurality of illumination fields using Fourier ptychography. |
| FILED | Saturday, July 14, 2018 |
| APPL NO | 16/035629 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 1/3216 (20130101) H04N 5/213 (20130101) H04N 5/217 (20130101) H04N 5/357 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10687898 | Trayanova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Patrick M. Boyle (Baltimore, Maryland); Sohail Zahid (Baltimore, Maryland) |
| ABSTRACT | According to some embodiments of the invention, a method for providing an atrial fibrillation (AF) ablation treatment plan includes receiving imaging data for at least a portion of an atrial region of a subject's heart, and processing the imaging data to characterize tissue as one of fibrotic tissue or non-fibrotic tissue. The method further includes calculating a metric of spatial distribution of at least a portion of the tissue characterized as fibrotic tissue from the processing the imaging data, identifying a cardiac tissue ablation target based on the metric, and providing an AF treatment plan that includes the cardiac tissue ablation target as at least a portion of the AF treatment plan. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 15/526199 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7275 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/5217 (20130101) A61B 18/1492 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 2018/00351 (20130101) A61B 2018/00357 (20130101) A61B 2018/00363 (20130101) A61B 2018/00577 (20130101) A61B 2034/104 (20160201) A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688040 | Wrenn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven P. Wrenn (Swarthmore, Pennsylvania); Stephen Dicker (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Steven P. Wrenn (Swarthmore, Pennsylvania); Stephen Dicker (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291774 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688189 | Moon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joong Ho Moon (Weston, Florida); Alfonso Barrios (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Joong Ho Moon (Weston, Florida); Alfonso Barrios (Miami, Florida) |
| ABSTRACT | A modulated guanidine substituted polymer or nanoparticle has a guanidine moiety or on a plurality of repeating units of a polymer or on the surface of a nanoparticle where the guanidine moiety is modulated as a substituted amidinourea or amidinocarbamate or salt thereof. The modulated guanidine substituted polymer or nanoparticle can be prepared by direct amination of a N-Boc protected guanidine substituted conjugated polymer or N-Boc protected guanidine substituted nanoparticle, where an amine or alcohol is combined in solution or suspension with the protected conjugated polymer or nanoparticle and the resulting mixture is heated. The modulated guanidine substituted polymer or nanoparticle can be used in a cancer treatment formulation. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/799375 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/32 (20130101) Original (OR) Class Heterocyclic Compounds C07D 491/18 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 34/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688192 | Chmielewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jean Anne Chmielewski (West Lafayette, Indiana); Mohamed Seleem (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to novel cleavable conjugates of antibiotics and an antibacterial cell-penetrating peptide, and methods to make and use the novel cleavable conjugates of antibiotics and an antibacterial cell-penetrating peptide. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280093 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/395 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 47/61 (20170801) A61K 47/64 (20170801) A61K 47/65 (20170801) A61K 47/552 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688203 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Xiankai Sun (Coppell, Texas); Yaowu Hao (Southlake, Texas); Sina Moeendarbari (Arlington, Texas) |
| ABSTRACT | In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 nm in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718643 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) A61K 9/5115 (20130101) A61K 49/0065 (20130101) A61K 49/0093 (20130101) A61K 49/183 (20130101) A61K 51/025 (20130101) A61K 51/1251 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1014 (20130101) A61N 5/1077 (20130101) A61N 2005/1024 (20130101) A61N 2005/1089 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) B01J 13/22 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/025 (20130101) B22F 9/14 (20130101) B22F 2001/0029 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) Y10T 428/2984 (20150115) Y10T 428/2989 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688442 | Mauter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania); The Pennsylvania State University (University Park, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Meagan Mauter (Pittsburgh, Pennsylvania); Manish Kumar (University Park, Pennsylvania) |
| ABSTRACT | The disclosure describes a method of forming highly ordered membrane protein crystals. The forming process is done in the presence of a magnetic field to exploit the diamagnetic anisotropy of the membrane protein. Further described is a method of magnetic alignment and crystallization of membrane proteins in two-dimensional (2D) sheets for protein structural characterization and applications in functional devices. Block co-copolymers are used in alternative embodiments to assist with the crystallization process. |
| FILED | Tuesday, July 05, 2016 |
| APPL NO | 15/741498 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/027 (20130101) B01D 67/0004 (20130101) Original (OR) Class B01D 69/06 (20130101) B01D 69/10 (20130101) B01D 69/144 (20130101) B01D 71/26 (20130101) B01D 71/52 (20130101) B01D 71/80 (20130101) B01D 2323/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688453 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Soroush Kahkeshani (Los Angeles, California) |
| ABSTRACT | A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/767979 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/0021 (20130101) A61K 9/0024 (20130101) A61K 9/0097 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2037/0023 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0815 (20130101) Original (OR) Class B01F 13/0059 (20130101) B01F 13/0077 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/1002 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688714 | Bottiglio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rebecca Kramer Bottiglio (New Haven, Connecticut); Michelle Ching-Sum Yuen (New Haven, Connecticut) |
| ABSTRACT | Methods and systems suitable for fabricating multi-layer elastic electronic devices, and elastic electronic devices formed thereby. A method of fabricating an elastomer-based electronic device includes printing a first liquid material and then a second liquid material on a fabric substrate that comprises fibers. The first and second liquid materials are sequentially printed with a three-dimensional printer that directly prints the first liquid material onto the fabric substrate so that the first liquid material wicks through some of the fibers of the fabric substrate and forms a solid matrix of an elastomer-based composite that comprises the matrix and the fabric substrate, after which the three-dimensional printer directly prints the second liquid material on the elastomer-based composite to form a film thereon. The elastomer-based composite and film are electrical components of the elastomer-based electronic device. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 15/662762 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/209 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2021/00 (20130101) B29K 2913/00 (20130101) B29K 2995/0006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/752 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) G01B 7/22 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/16 (20130101) H05K 1/038 (20130101) H05K 1/095 (20130101) H05K 1/162 (20130101) H05K 1/167 (20130101) H05K 3/0011 (20130101) H05K 3/1241 (20130101) H05K 3/1283 (20130101) H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689252 | Arnold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
| ABSTRACT | The present teachings provide methods for providing populations of single-walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture including such populations. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903661 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689484 | Cheng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
| ASSIGNEE(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
| INVENTOR(S) | Gang Cheng (Wilmette, Illinois) |
| ABSTRACT | In one or more embodiments, the present invention provides a method of forming compact, flexible, stable and biocompatible conducting polymer coating for bioelectronics devices. In one or more embodiments, the present invention relates to a novel method of synthesizing a sulfobetaine-functionalized conjugated polymer platform using 3,4-ethylenedioxythiophene (EDOT) as the conducting backbone (SBEDOT). This SBEDOT monomer is highly water-soluble and can be directly polymerized to form a densely packed film/coating on conductive or semi-conductive surfaces through electro-polymerization in a 100% aqueous solution without the need for organic solvents or surfactants. These polySBEDOT (PSBEDOT) coated surfaces have been shown to have electro-switchable antimicrobial/antifouling properties and excellent electrically conducting properties, which minimize infection, increase biocompatibility, and improve the performance of bioelectronics. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/764049 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) Original (OR) Class C08G 2261/18 (20130101) C08G 2261/44 (20130101) C08G 2261/51 (20130101) C08G 2261/94 (20130101) C08G 2261/143 (20130101) C08G 2261/1424 (20130101) C08G 2261/1452 (20130101) C08G 2261/3223 (20130101) Compositions of Macromolecular Compounds C08L 41/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) C09D 165/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689549 | Sitti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | nanoGriptech, Inc. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | NanoGriptech, Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Metin Sitti (Pittsburgh, Pennsylvania); Burak Aksak (Lubbock, Texas) |
| ABSTRACT | This invention identifies important geometric parameters of an adhesive microfiber with mushroom-shaped tip for improving and optimizing adhesive ability. The magnitude of pull-off stress is dependent on a wedge angle γ and the ratio of the tip radius to the stalk radius β of the mushroom-shaped fiber. Pull-off stress is also found to depend on a dimensionless parameter x, the ratio of the fiber radius to a length-scale related to the dominance of adhesive stress. Finally, the shape of edge tip, where the surface and sides of the mushroom-shaped tip join, is a factor that impacts strength of adhesion. Optimizing ranges for these parameters are identified. |
| FILED | Monday, February 10, 2014 |
| APPL NO | 14/766561 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) C09J 9/00 (20130101) Original (OR) Class C09J 2201/626 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/20 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2976 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689631 | Pfleger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Jose Hernandez-Lozada (Jena, Germany); Costas Maranas (State College, Pennsylvania); Matthew Grisewood (Mountaintop, Pennsylvania) |
| ABSTRACT | Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ ID NO:1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, M141, E142, Y145, and L146, gene constructs encoding and configured to express the mutated thioesterases in a transformed host cell, and host cells transformed to contain the gene constructs. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 16/535305 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689643 | Jelinek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Active Motif, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | ACTIVE MOTIF, INC. (Carlsbad, California) |
| INVENTOR(S) | Mary Anne Jelinek (Carlsbad, California); Brian Stanley Egan (Carlsbad, California); Joseph Fernandez (Carlsbad, California) |
| ABSTRACT | Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions. |
| FILED | Thursday, May 22, 2014 |
| APPL NO | 14/892911 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1034 (20130101) C12N 15/1065 (20130101) C12N 15/1068 (20130101) Original (OR) Class C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2522/101 (20130101) C12Q 2522/101 (20130101) C12Q 2535/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689660 | Schroeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Julian I. Schroeder (La Jolla, California); Cawas Engineer (San Diego, California) |
| ABSTRACT | In alternative embodiments, the invention provides compositions and methods for manipulating the exchange of water and/or carbon dioxide (CO2) through plant stomata by controlling the expression of a novel apoplastic subtilisin-like serine endopeptidase-like protein. In alternative embodiments, the invention provides plants having increased water use efficiency, and drought-resistant plants; and methods for engineering of water transpiration and water use efficiency in plants, and engineering plants with increased water use efficiency and drought-resistant plants. |
| FILED | Friday, June 21, 2013 |
| APPL NO | 14/408234 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690290 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Wonhee Lee (Daejeon, South Korea) |
| ABSTRACT | A particle focusing system includes an inlet; an inertial focusing microchannel disposed in a substrate and connected to the inlet; and a pressure/flow source configured to drive a particle-containing fluid through the inertial focusing microchannel, where the inertial focusing microchannel includes a side wall having an irregular surface. The side wall includes a first irregularity protruding from a baseline surface away from a longitudinal axis of the inertial focusing microchannel. Alternatively or additionally, the first irregularity and the baseline surface form an angle more than or equal to 135 degrees. The inertial focusing microchannel may have a substantially rectangular cross-section having a height and a width, and a ratio of height to width is approximately 5:4 to 4:1. The system may also include a downstream expanding region having a side wall, where the side wall has a stepped surface. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/276974 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Pipe-line Systems; Pipe-lines F17D 1/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 2015/1415 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/85978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690489 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Mohit Gupta (New York, New York); Shree K. Nayar (New York, New York) |
| ABSTRACT | Systems, methods, and media for performing shape measurement are provided. In some embodiments, systems for performing shape measurement are provided, the systems comprising: a projector that projects onto a scene a plurality of illumination patterns, wherein each of the illumination patterns has a given frequency, each of the illumination patterns is projected onto the scene during a separate period of time, three different illumination patterns are projected with a first given frequency, and only one or two different illumination patterns are projected with a second given frequency; a camera that detects an image of the scene during each of the plurality of periods of time; and a hardware processor that is configured to: determine the given frequencies of the plurality of illumination patterns; and measure a shape of an object in the scene. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/853246 |
| ART UNIT | 2483 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/254 (20130101) G01B 11/2536 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4661 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690592 | Settles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Andrew M. Settles (Gainesville, Florida); Jeffery Lynn Gustin, II (Gainesville, Florida) |
| ABSTRACT | Methods for sorting haploid maize kernels in haploid induction crosses are provided. A method of sorting haploid kernels can include capturing near-infrared (NIR) spectra and applying a general multivariate statistical model to the acquired NIR spectra to discriminate haploid kernels from diploid-hybrid kernels mixed therein. NIR spectra can be collected on a single kernel using a high-throughput apparatus such that the amount of time required to analyze individual kernels can be significantly reduced in comparison to existing NIR technology and in comparison to traditional manual sorting. |
| FILED | Tuesday, March 14, 2017 |
| APPL NO | 16/084422 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/342 (20130101) B07C 5/3425 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) Original (OR) Class G01N 21/3563 (20130101) G01N 2201/129 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690604 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Tongcang Li (West Lafayette, Indiana); Thai Hoang (Lafayette, Indiana); Jonghoon Ahn (West Lafayette, Indiana); Jaehoon Bang (West Lafayette, Indiana) |
| ABSTRACT | Sensors and methods are provided that include a diamond material containing a nitrogen vacancy center, the diamond material being configured to be exposed to an environment comprising one or more gases, an optical light source configured to excite the nitrogen vacancy center of the diamond material with an optical light beam produced therefrom, a detector configured to detect a signal originating from the diamond material in response to the optical light beam exciting the nitrogen vacancy center, and the capability of analyzing the signal to identify a specific gas in the environment. Also included are levitated spin-optomechanical systems capable of elevating in a vacuum a diamond material containing a nitrogen vacancy center, applying microwave radiation to the diamond material for controlling and flipping the electron spin of the nitrogen vacancy center, and monitoring electron spin of the nitrogen vacancy center. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/681756 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/006 (20130101) Original (OR) Class G01N 24/10 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690661 | Tyo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Keith E. J. Tyo (Evanston, Illinois); Adebola V. Adeniran (Evanston, Illinois); John W. Bostick (Evanston, Illinois); Dante A. Pertusi (Evanston, Illinois); Sarah Christine Stainbrook (Evanston, Illinois) |
| ABSTRACT | Provided herein are compositions and systems comprising yeast-based biosensors (YBBs) and methods of use thereof. In particular, YBBs are provided for the detection and/or quantification of an analyte (e.g., peptide analyte) in a sample (e.g., a biological sample, environmental sample, etc.). In some embodiments, provided herein are diagnostic compositions, devices, and methods comprising yeast-based biosensors (YBBs) engineered to detect analytes (e.g., peptides (e.g., biomarker peptides, etc.), etc.). In some embodiments, YBBs comprise (a) recognition element (e.g., receptor (e.g., modified yeast receptor, etc.), etc.) on the exterior of the biosensor (e.g., for binding and or recognition of the analyte (e.g., peptide)), and (b) a reporter that signals binding or recognition of the analyte. In some embodiments, a recognition element is a cell surface receptor. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 15/324986 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/395 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class G01N 2333/395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690675 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ronghu Wu (Atlanta, Georgia); Weixuan Chen (Atlanta, Georgia) |
| ABSTRACT | Compositions and methods for enriching glycocompounds are disclosed which can comprise a glycocompound bound to a boronic acid compound which can be conjugated to a dendrimer. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952946 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 33/6842 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 2440/38 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690817 | Shalaev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vladimir Shalaev (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Xingjie Ni (Albany, California); Satoshi Ishii (Hyogo, Japan) |
| ABSTRACT | An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000843 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/834 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691585 | Meliou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Alexandra Meliou (Amherst, Massachusetts); Yuriy Brun (Amherst, Massachusetts) |
| ABSTRACT | A system includes a memory system having computer readable instructions and one or more processors for executing the computer readable instructions. The computer readable instructions include identifying input characteristic subsets for a system under test based on an input schema, generating discrimination test cases including a combination of inputs for the system under test based on the input characteristic subsets, and performing a pruning operation to reduce a number of the discrimination test cases based on identifying a superset of input characteristics that includes at least one of the input characteristic subsets having a discrimination score above a threshold value. The computer readable instructions further include determining discrimination scores based on applying one or more of the discrimination test cases remaining after the pruning operation to the system under test and observing an output, and outputting a measurement of discrimination of the system under test based on the discrimination scores. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205473 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3672 (20130101) G06F 11/3684 (20130101) Original (OR) Class G06F 11/3688 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691836 | Kose et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Selcuk Kose (Tampa, Florida); Weize Yu (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Selcuk Kose (Tampa, Florida); Weize Yu (Tampa, Florida) |
| ABSTRACT | Methods and systems are provided for a charge withholding converter reshuffling technique that decorrelates input power of a multi-phase switched capacitor (SC) voltage converter relative to the output power provided to a load. The load may be a cryptographic device. The technique provides a countermeasure against power analysis attacks. A controller including a first random number generator coupled to the stages of the SC voltage converter controls gating for charging a first subset of the stages. A controller including a second random number generator coupled the stages of the SC voltage converter controls gating for discharging a second subset the stages. A number of the switched capacitor stages maintain their charge beyond the switch period in which they are charged. The SC voltage converter withholds a random portion of input charge and delivers this charge to the load after a random time period. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/967044 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 7/582 (20130101) G06F 21/81 (20130101) G06F 21/556 (20130101) G06F 21/755 (20170801) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/003 (20130101) H04L 9/12 (20130101) H04L 9/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692158 | Meyn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); INRIA (French Institute for Research in Computer Science and Automation) (Paris, France) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); INRIA (French Institute for Research in Computer Science and Automation) (Paris, France) |
| INVENTOR(S) | Sean Meyn (Gainesville, Florida); Ana Busic (Paris, France) |
| ABSTRACT | A system, method and apparatus for providing ancillary services to a power grid using a power consumption component at a customer premises. The apparatus may control a load with discrete, finite states of power or an on/off load at a customer premises using a controller. The controller may comprise a processor, which may be configured to receive a regulation signal associated with an ancillary service for the power grid; determine whether to modify a state of power of the power consumption component based on a probability function, local measurement at the premises, and the received regulation signal; and based at least in part on a determination to modify the state of power of the power consumption component, modify the state of power of the power consumption component. The system may be distributed, with different controllers at different customer premises independently making power state decisions. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/740328 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) H02J 3/28 (20130101) H02J 3/386 (20130101) H02J 13/0006 (20130101) H02J 2203/20 (20200101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/3225 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/763 (20130101) Y02E 40/72 (20130101) Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/123 (20130101) Y04S 20/222 (20130101) Y04S 40/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692660 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiangfeng Duan (Los Angeles, California); Yuxi Xu (Los Angeles, California) |
| ABSTRACT | An electrochemical capacitor includes a pair of electrodes and an electrolyte disposed between the pair of electrodes. At least a first electrode of the pair of electrodes includes a graphene framework film, and the graphene framework film includes interconnected graphene sheets with nanopores formed in the graphene sheets. |
| FILED | Wednesday, July 30, 2014 |
| APPL NO | 15/035108 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/192 (20170801) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/28 (20130101) H01G 11/36 (20130101) Original (OR) Class H01G 11/46 (20130101) H01G 11/70 (20130101) H01G 11/86 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692700 | Pallav et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Kumar Pallav (Sunnyvale, California); Rajiv Malhotra (Corvallis, Oregon); Ishan Saxena (Evanston, Illinois); Kornel Ehmann (Evanston, Illinois); Jian Cao (Wilmette, Illinois) |
| ABSTRACT | A system for laser-induced plasma micromachining of a work-piece includes a dielectric fluid, a dielectric fluid supply device, a laser, a processor, and a memory. The dielectric fluid supply device is arranged to hold a work-piece in the dielectric fluid or to direct the dielectric fluid onto the work-piece. The laser is arranged to emit a pulsed laser-beam. The processor is in electronic communication with the laser. The memory is in electronic communication with the processor. The memory includes programming code for execution by the processor. The programming code is programmed to direct the laser to deliver the pulsed laser-beam into the dielectric fluid to create a plasma generated at a focal point of the pulsed laser-beam in the dielectric fluid to micromachine, using the plasma, the work-piece disposed adjacent to the focal point. |
| FILED | Tuesday, August 23, 2016 |
| APPL NO | 15/244172 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/14 (20130101) H01J 37/302 (20130101) H01J 37/3266 (20130101) H01J 37/32339 (20130101) Original (OR) Class H01J 37/32669 (20130101) H01J 37/32715 (20130101) H01J 37/32926 (20130101) H01J 2237/334 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693071 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yang Yang (Los Angeles, California); Jingbi You (Los Angeles, California); Lei Meng (Los Angeles, California) |
| ABSTRACT | An opto-electronic device includes a first electrode, a first buffer layer formed on the first electrode, and a perovskite semiconductor active layer formed on the first buffer layer. The opto-electronic device further includes a second buffer layer formed on the perovskite semiconductor active layer, and a second electrode formed on the second buffer layer. The first buffer layer, the second buffer layer, and the perovskite semiconductor active layer each consists essentially of inorganic materials. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/553483 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0032 (20130101) Original (OR) Class H01L 51/0037 (20130101) H01L 51/422 (20130101) H01L 51/4233 (20130101) H01L 51/4246 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693098 | O'Carroll |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Deirdre O'Carroll (Metuchen, New Jersey) |
| ABSTRACT | Light-emitting devices having an emitting layer containing a light-emitting organic or organometallic material and a nanostructure, the nanostructure having strong local electric fields at visible electromagnetic wavelengths that spectrally and spatially overlap with the light-emitting material. The spectral and spatial overlap of the electric fields of the nanostructure with the light emitting material uses high LDOS provided by the nanostructures to enable excited triplet electronic states in the material to emit light faster than without the nanostructure. This faster light emission from triplet-excited states leads to more stable emission from the light emitting material because it prevents buildup of triplet-excited states, which ordinarily can lead to quenching of light emission from the light emitting material. Among the many different possibilities contemplated, the nanostructure may advantageously be made of a dielectric material or a plasmonic metal material, such as SiO2, TiO2, ZnO, Al or Ag. It is further contemplated that the light-emitting material be capable of exhibiting at least one of phosphorescence or thermally-assisted delayed fluorescence. Many light-emitting materials, including blue light emitters, may be utilized, and may also be doped into a host material. It is still further contemplated that the nanostructure may be a nanoantenna, a nanoparticle, such as a sphere or rod, a nanoporous film, or an imprinted grating, and the nanostructure may be on either side of the light-emitting material, or may be surrounded by or embedded in the host material. The light-emitting device may also advantageously include other layers, including but not limited a hole transport layer, a hole blocking layer, an electron transport layer, a hole injection layer, or an electron injection layer. Further, the device may also be configured for use in various applications, including but not limited to bioimaging, photochemistry, and single molecule spectroscopy. |
| FILED | Thursday, August 02, 2018 |
| APPL NO | 16/053116 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) H01L 51/0072 (20130101) H01L 51/0085 (20130101) H01L 51/502 (20130101) H01L 51/5016 (20130101) H01L 51/5028 (20130101) Original (OR) Class H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5088 (20130101) H01L 51/5092 (20130101) H01L 51/5096 (20130101) H01L 51/5206 (20130101) H01L 51/5221 (20130101) H01L 2251/301 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693206 | Bahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gaurav Bahl (Champaign, Illinois); Christopher Peterson (Champaign, Illinois) |
| ABSTRACT | A nonreciprocal device includes a waveguide through which waves at a first frequency propagate with a first wavevector and with a second wavevector in a direction opposite to the first wavevector; a frequency-dependent device that operates within a frequency range and modifies the waves through the waveguide in a way that is dependent on the first frequency; and a set of couplers to couple the waveguide and the frequency-dependent device. Coupling rates of the set of couplers are modulated to enable nonreciprocal coupling, with respect to the frequency-dependent device, of the first wavevector compared to the second wavevector. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/121915 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4208 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/32 (20130101) Original (OR) Class H01P 1/36 (20130101) H01P 1/38 (20130101) H01P 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693416 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Jr-Shin Li (St. Louis, Missouri); Anatoly Zlotnik (St. Louis, Missouri) |
| ABSTRACT | A system for entraining an oscillator ensemble is disclosed that includes a plurality of oscillators in an entrained phase pattern. The system includes an entrainment device operatively coupled to each non-linear oscillator of the oscillator ensemble, and the entrainment control device is configured to deliver a 2π-periodic control signal v(θ) to all oscillators of the plurality of oscillators to induce the entrained phase pattern. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436582 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 27/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693544 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Yunfei Ma (Santa Clara, California); Zhihong Luo (Cambridge, Massachusetts); Christoph Steiger (Cambridge, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | Multiple antennas of a beamformer may simultaneously transmit wireless signals at different frequencies. The signals may comprise synchronized, identical wireless commands, each at a different carrier frequency. The transmitted signals may constructively and destructively interfere with each other at a receiver antenna, to form a beat signal. When the transmitted signals constructively interfere, the beat signal may cause a voltage in the receiver to exceed a threshold voltage. The threshold voltage may be a minimum voltage at which a device, which is operatively connected to the receiver antenna, is able to perform energy harvesting or wireless communication. The beamformer may operate under blind channel conditions, because the transmitted frequencies may be selected in such a way as to maximize peak power delivered under all possible channel conditions. The beamformer may deliver wireless power to a sensor or actuator that is located deep inside bodily tissue. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 16/391740 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10217 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class H04B 13/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694123 | Cossairt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Oliver Strider Cossairt (Evanston, Illinois); Jason Holloway (Houston, Texas); Ashok Veeraraghavan (Houston, Texas); Manoj Kumar Sharma (Houston, Texas); Yicheng Wu (Houston, Texas) |
| ABSTRACT | A method for imaging objects includes illuminating an object with a light source of an imaging device, and receiving an illumination field reflected by the object. An aperture field that intercepts a pupil of the imaging device is an optical propagation of the illumination field at an aperture plane. The method includes receiving a portion of the aperture field onto a camera sensor, and receiving a sensor field of optical intensity. The method also includes iteratively centering the camera focus along the Fourier plane at different locations to produce a series of sensor fields and stitching together the sensor fields in the Fourier domain to generate an image. The method also includes determining a plurality of phase information for each sensor field in the series of sensor fields, applying the plurality of phase information to the image, receiving a plurality of illumination fields reflected by the object, and denoising the intensity of plurality of illumination fields using Fourier ptychography. |
| FILED | Saturday, July 14, 2018 |
| APPL NO | 16/035629 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 1/3216 (20130101) H04N 5/213 (20130101) H04N 5/217 (20130101) H04N 5/357 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694526 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania); University of Oulu (Linnanmaa, Finland) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); Univeristy of Oulu (Linnanmaa, Finland) |
| INVENTOR(S) | Danh H. Nguyen (Philadelphia, Pennsylvania); Anton Paatelma (Oulu, Finland); Harri Saarnisaari (Oulu, Finland); Nagarajan Kandasamy (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania) |
| ABSTRACT | A learning protocol for distributed antenna state selection in directional cognitive small-cell networks is described. Antenna state selection is formulated as a nonstationary multi-armed bandit problem and an effective solution is provided based on the adaptive pursuit method from reinforcement learning. A cognitive small cell testbed, called WARP-TDMAC, provides a useful software-defined radio package to explore the usefulness of compact, electronically reconfigurable antennas in dense small-cell configurations. A practical implementation of the adaptive pursuit method provides a robust distributed antenna state selection protocol for cognitive small-cell networks. Test results confirm that directionality provides significant advantages over omnidirectional transmission which suffers high throughput reduction and complete link outages at above-average jamming or cross-link interference power. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/720951 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/123 (20130101) G06N 7/005 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/16 (20130101) H04L 43/087 (20130101) Wireless Communication Networks H04W 16/06 (20130101) H04W 16/26 (20130101) H04W 56/001 (20130101) H04W 72/082 (20130101) Original (OR) Class H04W 72/0446 (20130101) H04W 74/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10688163 | Jackson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Paul J. Jackson (Livermore, California); Brian E. Souza (Livermore, California); Feliza A. Bourguet (Livermore, California); Matthew A. Coleman (Oakland, California) |
| ABSTRACT | Targeted antimicrobials are described and related, compositions, methods and systems. |
| FILED | Monday, August 11, 2014 |
| APPL NO | 14/457035 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) Original (OR) Class A61K 45/06 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Enzymes C12Y 305/01028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/32 (20130101) G01N 2333/914 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688472 | Berry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | David A. Berry (Mount Morris, Pennsylvania); Dushyant Shekhawat (Morgantown, West Virginia); Daniel J. Haynes (Morgantown, West Virginia); Mark W. Smith (Fairmont, West Virginia) |
| ABSTRACT | One or more embodiments relates to a method of catalytically converting a reactant gas mixture for pollution abatement of products of hydrocarbon fuel combustion. The method provides substituted mixed-metal oxides where catalytically active metals are substituted within the crystal lattice to create an active and well dispersed metal catalyst available to convert the reactant gas mixture. Embodiments may be used with gasoline and diesel fueled internal combustion engine exhaust, although specific embodiments may differ somewhat for each. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994201 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/945 (20130101) B01D 2255/40 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) Original (OR) Class B01J 35/04 (20130101) B01J 35/0006 (20130101) B01J 35/026 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/035 (20130101) F01N 3/101 (20130101) F01N 3/0814 (20130101) F01N 2570/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688556 | Matsui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Hiroshi Matsui (Glen Rock, New Jersey); Zengyan Wei (Corona, New York); Justin Fang (New York, New York) |
| ABSTRACT | Nanocages are formed by etching nancubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477601 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) Original (OR) Class B22F 1/0022 (20130101) B22F 1/0062 (20130101) B22F 1/0085 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 9/24 (20130101) B22F 2001/0037 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/00 (20130101) C23F 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689044 | Tolley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael T. Tolley (Cambridge, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Bobak Mosadegh (Boston, Massachusetts); Robert J. Wood (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A pneumatically powered, fully untethered mobile soft robot is described. Composites consisting of silicone elastomer, polyaramid fabric, and hollow glass microspheres were used to fabricate a sufficiently large soft robot to carry the miniature air compressors, battery, valves, and controller needed for autonomous operation. Fabrication techniques were developed to mold a 0.65 meter long soft body with modified Pneumatic network actuators capable of operating at the elevated pressures (up to 138 kPa) required to actuate the legs of the robot and hold payloads of up to 8 kg. The soft robot is safe to handle, and its silicone body is innately resilient to a variety of adverse environmental conditions including snow, puddles of water, direct (albeit limited) exposure to flames, and the crushing force of being run over by an automobile. |
| FILED | Tuesday, June 30, 2015 |
| APPL NO | 14/755026 |
| ART UNIT | 3611 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 18/06 (20130101) Motor Vehicles; Trailers B62D 57/02 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/09 (20130101) Y10S 901/22 (20130101) Y10S 901/27 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689252 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
| ABSTRACT | The present teachings provide methods for providing populations of single-walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture including such populations. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903661 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689491 | Durban et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Matt Durban (Livermore, California); Eric Duoss (Dublin, California); Jeremy Lenhardt (Tracy, California); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | In one embodiment, a silicone-based ink for additive manufacturing includes a vinyl-terminated siloxane macromer, a hydrophobic reinforcing filler, and a rheology modifying additive. In another embodiment, a method of additive manufacturing with silicone-based ink includes adding a mixture that includes a vinyl-terminated siloxane macromer, a hydrophobic reinforcing filler, and a rheology modifying additive to a cartridge for additive manufacturing, extruding the mixture through the cartridge to form a structure, and curing the mixture to at least a predefined extent. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/721528 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0879 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/12 (20130101) C08G 77/20 (20130101) C08G 77/442 (20130101) Original (OR) Class C08G 81/024 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/11 (20180101) C08K 3/36 (20130101) C08K 5/0025 (20130101) C08K 5/56 (20130101) C08K 5/56 (20130101) C08K 5/5425 (20130101) C08K 9/06 (20130101) Compositions of Macromolecular Compounds C08L 83/00 (20130101) C08L 83/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/101 (20130101) C09D 11/102 (20130101) C09D 183/04 (20130101) C09D 183/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/4866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689634 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | David N. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho); Thomas E. Ward (PA Furnace, Pennsylvania) |
| ABSTRACT | A genetically modified organism comprising: at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus acidocaldarius and encoding a polypeptide involved in at least partially degrading, cleaving, transporting, metabolizing, or removing polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups; and at least one nucleic acid sequence and/or at least one recombinant nucleic acid encoding a polypeptide involved in fermenting sugar molecules to a product. Additionally, enzymatic and/or proteinaceous extracts may be isolated from one or more genetically modified organisms. The extracts are utilized to convert biomass into a product. Further provided are methods of converting biomass into products comprising: placing the genetically modified organism and/or enzymatic extracts thereof in fluid contact with polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, and/or xylan-, glucan-, galactan-, or mannan-decorating groups. |
| FILED | Monday, July 15, 2019 |
| APPL NO | 16/511133 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 7/065 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 302/01139 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689638 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vicki S. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Jeffrey A. Lacey (Idaho Falls, Idaho); Brady D. Lee (West Richland, Washington); David W. Reed (Idaho Falls, Idaho); Francisco F. Roberto (Highlands Ranch, Colorado); David N. Thompson (Idaho Falls, Idaho) |
| ABSTRACT | Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700864 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/88 (20130101) Original (OR) Class C12N 9/1029 (20130101) C12N 15/74 (20130101) C12N 15/75 (20130101) Enzymes C12Y 203/01009 (20130101) C12Y 402/01055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689652 | Stampfer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Martha R. Stampfer (Oakland, California); James C. Garbe (San Francisco, California) |
| ABSTRACT | Methods for inducing non-clonal immortalization of normal epithelial cells by directly targeting the two main senescence barriers encountered by cultured epithelial cells. In finite lifespan pre-stasis human mammary epithelial cells (HMEC), the stress-associated stasis barrier was bypassed, and in post-stasis HMEC, the replicative senescence barrier, a consequence of critically shortened telomeres, was bypassed. Early passage non-clonal immortalized lines exhibited normal karyotypes. Methods of efficient HMEC immortalization, in the absence of “passenger” genomic errors, should facilitate examination of telomerase regulation and immortalization during human carcinoma progression, methods for screening for toxic and environmental effect on progression, and the development of therapeutics targeting the process of immortalization. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/256395 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0631 (20130101) C12N 5/0693 (20130101) C12N 15/62 (20130101) C12N 15/1136 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2501/606 (20130101) C12N 2510/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5014 (20130101) G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689727 | Freiderich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | John William Freiderich (Oak Ridge, Tennessee); Huimin Luo (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Sheng Dai (Knoxville, Tennessee) |
| ABSTRACT | A method for extracting a rare earth element from a rare earth-containing substance, the method comprising mixing the rare earth-containing substance with a protic ionic liquid, such as: wherein R1 is selected from hydrogen atom and hydrocarbon groups containing 1 to 6 carbon atoms; R2 and R3 are independently selected from hydrocarbon groups containing 1 to 12 carbon atoms; and X− is an anionic species; to produce a composition of the formula (RE)(amide)yXz at least partially dissolved in the protic ionic liquid, wherein RE is at least one rare earth element having an atomic number selected from 39, 57-71, and 90-103; y is 2-6; z is a number that charge balances the total positive charge of RE; and the amide is the conjugate base of the cationic portion of the protic ionic liquid of Formula (1) and has the following formula: |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/135753 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/0014 (20130101) Original (OR) Class C22B 59/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689730 | Fang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Zhigang Zak Fang (Salt Lake City, Utah); Ying Zhang (Salt Lake City, Utah); Yang Xia (Salt Lake City, Utah); Pei Sun (Salt Lake City, Utah) |
| ABSTRACT | A method (500) for producing a titanium product is disclosed. The method (500) can include obtaining TiO2-slag (501) and reducing impurities in the TiO2-slag (502) to form purified TiO2 (503). The method (500) can also include reducing the purified TiO2 using a metallic reducing agent (504) to form a hydrogenated titanium product comprising TiH2 (505). The hydrogenated titanium product can be dehydrogenated (506) to form a titanium product (508). The titanium product can also be optionally deoxygenated (507) to reduce oxygen content. |
| FILED | Friday, November 06, 2015 |
| APPL NO | 14/935245 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/20 (20130101) B22F 2201/013 (20130101) B22F 2301/205 (20130101) Non-metallic Elements; Compounds Thereof; C01B 6/02 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 1/02 (20130101) C22B 3/04 (20130101) C22B 7/04 (20130101) Original (OR) Class C22B 34/1204 (20130101) C22B 34/1213 (20130101) C22B 34/1259 (20130101) C22B 34/1268 (20130101) C22B 34/1277 (20130101) C22B 34/1286 (20130101) C22B 34/1295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690056 | Berry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Stanley Kevin Widener (Greenville, South Carolina); Michael John Hughes (State College, Pennsylvania); James Scott Flanagan (Simpsonville, South Carolina); Joseph Vincent Citeno (Greenville, South Carolina); Kevin Weston McMahan (Greenville, South Carolina) |
| ABSTRACT | A segmented annular combustion system includes an alternating arrangement of fuel nozzles and integrated combustor nozzles. The fuel nozzles deliver fuel to the primary combustion zones. The integrated combustor nozzles include an inner liner segment, an outer liner segment, and a fuel injection panel extending between the liner segments. The fuel injection panel includes injection outlets on one or both side walls to deliver a combustible mixture to the secondary combustion zones. Each fuel injection panel, which provides a boundary between adjacent primary and secondary combustion zones, includes an aft end that defines a turbine nozzle. The segmented annular combustion system is part of a gas turbine. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 15/464394 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/18 (20130101) Original (OR) Class F02C 7/22 (20130101) F02C 7/222 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/005 (20130101) F23R 3/06 (20130101) F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/34 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 3/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690288 | Griffith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Saul Griffith (San Francisco, California); Rustie McCumber (Albany, California); Shara Maikranz (San Francisco, California); Jonathan Ward (San Francisco, California); Tucker Gilman (San Francisco, California) |
| ABSTRACT | A vessel for storing fluid, the vessel including a liner having a liner body that defines: a liner cavity; a plurality of flexible connector portions that include a corrugated length that provides for flexibility of the respective connector portions, the connector portions having a first maximum diameter; a plurality of elongated tubing portions between the respective flexible connector portions, the elongated tubing portions having a second minimum diameter that is larger than the first maximum diameter of the flexible connector portions; and a plurality of taper portions coupling adjoining flexible connector portions and tubing portions configured to provide a transition between a smaller diameter of the connector portion and a larger diameter of the tubing portion. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183614 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/16 (20130101) Original (OR) Class F17C 2201/056 (20130101) F17C 2201/0138 (20130101) F17C 2201/0166 (20130101) F17C 2201/0195 (20130101) F17C 2203/0604 (20130101) F17C 2203/0619 (20130101) F17C 2203/0621 (20130101) F17C 2203/0624 (20130101) F17C 2203/0663 (20130101) F17C 2205/0111 (20130101) F17C 2205/0138 (20130101) F17C 2209/221 (20130101) F17C 2209/2109 (20130101) F17C 2209/2118 (20130101) F17C 2209/2127 (20130101) F17C 2209/2154 (20130101) F17C 2209/2163 (20130101) F17C 2221/033 (20130101) F17C 2223/035 (20130101) F17C 2223/0123 (20130101) F17C 2270/0168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690350 | Berry |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina) |
| ABSTRACT | A combustor with axially staged fuel injection includes a plurality of nozzle segments annularly arranged about a center fuel nozzle. Each nozzle segment includes a fuel plenum partially defined between a forward plate and an aft plate and a plurality of tubes that extends through the fuel plenum and the aft plate. A panel fuel injector extends axially downstream from the aft plate and includes an outer wall, an inner wall, a plurality of outlets defined along at least one of the outer wall and the inner wall and a plurality of premix channels defined between the outer wall and the inner wall. Each premix channel is in fluid communication with a fuel supply, a compressed air supply and a respective outlet of the plurality of outlets. |
| FILED | Monday, November 28, 2016 |
| APPL NO | 15/361840 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/02 (20130101) F23R 3/06 (20130101) F23R 3/20 (20130101) F23R 3/26 (20130101) F23R 3/28 (20130101) F23R 3/045 (20130101) F23R 3/286 (20130101) F23R 3/343 (20130101) F23R 3/346 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690485 | Koester et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | David J. Koester (Nashville, Tennessee); Douglas Adams (Brentwood, Tennessee); Raymond Martin Bond (Nashville, Tennessee); Garrett W. Thorne (Nashville, Tennessee) |
| ABSTRACT | A system for determining one or more characteristics of a carbon fiber tow. The system including a first laser profilometer, a second laser profilometer, and a controller. The first laser profilometer is located on a first side of the carbon fiber tow. The second laser profilometer is located on a second side of the carbon fiber tow. The controller is configured to receive, from the first profilometer, a first profile of the first side of the carbon fiber tow, and receive, from the second profilometer, a second profile of the second side of the carbon fiber tow. The controller is further configured to determine at least one characteristic selected from a group consisting of a tow width of the carbon fiber tow, a tow fuzz of the carbon fiber tow, a tow thickness of the carbon fiber tow, and a tow angle of the carbon fiber tow, the at least one characteristic based on the first profile and the second profile. The controller further configured to output the at least one characteristic of the carbon fiber tow. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/920187 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/02 (20130101) G01B 11/06 (20130101) G01B 11/24 (20130101) Original (OR) Class G01B 11/26 (20130101) G01B 11/046 (20130101) G01B 2210/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/952 (20130101) G01N 21/8914 (20130101) G01N 21/8915 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690562 | Rieker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Gregory B. Rieker (Boulder, Colorado); Kuldeep Prasad (Vienna, Virginia); Caroline B. Alden (Boulder, Colorado); Sean C. Coburn (Longmont, Colorado); Robert J. Wright (Boulder, Colorado) |
| ABSTRACT | A system for detecting gas leaks and determining their location and size. A data gathering portion of the system utilizes a chosen geometrical configuration to collect path-integrated spectroscopic data over multiple paths around an area. A processing portion of the system applies a transport model together with meteorological data of the area to generate an influence function of possible leak locations on gas detector measurement paths, and applies an inversion model to the influence function, prior data, and the spectroscopic data to generate gas source size and location. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 16/343363 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) G01M 3/16 (20130101) Original (OR) Class G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0027 (20130101) G01N 33/0062 (20130101) Meteorology G01W 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690565 | Haske et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Kyle J. Haske (Willow Springs, Illinois); James E. Smith (Lemont, Illinois); Mark R. Sakowski (Willowbrook, Illinois); Donald E. Preuss (Hinsdale, Illinois) |
| ABSTRACT | The invention provides a system for detecting leaks in glovebox gloves, the system having a first seal within a glovebox aperture; a second seal contacting exterior surfaces of a glovebox, wherein the exterior surfaces define a periphery of the aperture; a first fluid supply for circumferentially expanding the first seal against center facing surfaces of the aperture to a first pressure; a second fluid supply for inflating the glove to a second pressure; and a pressure gauge for detecting a pressure decrease of the second pressure. Also provided is an in situ method for detecting leaks in glove box gloves, the method having the steps of applying a radially directed force to inside surfaces of cuffs of the gloves to hermetically seal the gloves from the exterior of the glovebox, thereby establishing a seal; inflating the gloves to a pressure; and monitoring the pressure for any decrease in pressure. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 15/712877 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 21/02 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/3209 (20130101) Original (OR) Class G01M 3/3218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690809 | Kamali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seyedeh Mahsa Kamali (Arcadia, California); Ehsan Arbabi (Arcadia, California); Amir Arbabi (Sunderland, Massachusetts); Yu Horie (Pasadena, California); MohammadSadegh Faraji-Dana (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | A metasurface is defined by an array of scattering elements having a U shape, where the geometrical dimensions determining the U shape are determined according to the different phase profiles that the metasurface is meant to generate in response to an incident electromagnetic wave. The metasurface, therefore, generates different phase shifts as a function of the incident electromagnetic wave. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125546 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class G02B 1/02 (20130101) G02B 5/0294 (20130101) G02B 5/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691787 | Ewing |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel Jonathan Ewing (Overland Park, Kansas) |
| ABSTRACT | A method and apparatus for reading unique identifiers of an integrated circuit. The unique identifiers may be physically unclonable functions (PUFs), formed by high energy ions implanted into semiconductor material of the integrated circuit. The method may include electrically or optically stimulating each of the PUFs and sensing with an optical sensor optical characteristics of resulting light emitted from the PUFs. Then the method may include comparing values associated with the optical characteristics of the PUFs with groups of stored values in a circuit database. Each of the groups of stored values may be associated with optical characteristics of PUFs of a known authentic circuit. The method may then include the controller providing verification of authenticity of the integrated circuit when each of the values associated with the optical characteristics of the PUFs match the stored values of at least one of the groups in the circuit database. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/936605 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/66 (20130101) G01N 21/6489 (20130101) G01N 2201/12 (20130101) Electric Digital Data Processing G06F 21/44 (20130101) Original (OR) Class G06F 21/45 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692635 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yanfeng Jiang (Minneapolis, Minnesota) |
| ABSTRACT | A bulk permanent magnetic material may include between about 5 volume percent and about 40 volume percent Fe16N2 phase domains, a plurality of nonmagnetic atoms or molecules forming domain wall pinning sites, and a balance soft magnetic material, wherein at least some of the soft magnetic material is magnetically coupled to the Fe16N2 phase domains via exchange spring coupling. In some examples, a bulk permanent magnetic material may be formed by implanting N+ ions in an iron workpiece using ion implantation to form an iron nitride workpiece, pre-annealing the iron nitride workpiece to attach the iron nitride workpiece to a substrate, and post-annealing the iron nitride workpiece to form Fe16N2 phase domains within the iron nitride workpiece. |
| FILED | Wednesday, June 14, 2017 |
| APPL NO | 15/622785 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 11/001 (20130101) B22D 11/0622 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 7/08 (20130101) Alloys C22C 29/16 (20130101) C22C 38/001 (20130101) C22C 2202/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/26 (20130101) C23C 8/80 (20130101) C23C 14/48 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/10 (20130101) Original (OR) Class H01F 1/34 (20130101) H01F 1/055 (20130101) H01F 1/086 (20130101) H01F 1/147 (20130101) H01F 1/0579 (20130101) H01F 41/0253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692710 | Prabhakaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Aneesh Prabhakaran (Richland, Washington); Yehia M. Ibrahim (Richland, Washington); Sandilya V. B. Garimella (Richland, Washington) |
| ABSTRACT | A method of manipulating ions comprises injecting ions between a first surface and a second surface positioned parallel to and spaced apart from each other and defining a central axis therebetween, wherein the first surface comprises first outer electrodes coupled to the first surface and a first inner array of electrodes coupled to the first surface and positioned between the first outer electrodes, wherein the second surface comprises second outer electrodes coupled to the second surface and a second inner array of electrodes coupled to the second surface and positioned between the second outer electrodes, and applying a frequency modulated RF voltage to at least one electrode of the first inner array of electrodes or the second inner array of electrodes to confine ions between the first surface and the second surface and to guide ions between the first surface and the second surface along the central axis. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/194161 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) Original (OR) Class H01J 49/062 (20130101) H01J 49/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692999 | Banerjee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Monolith Semiconductor Inc. (Round Rock, Texas) |
| ASSIGNEE(S) | MONOLITH SEMICONDUCTOR INC. (Round Rock, Texas) |
| INVENTOR(S) | Sujit Banerjee (Round Rock, Texas); Kevin Matocha (Round Rock, Texas); Kiran Chatty (Round Rock, Texas) |
| ABSTRACT | A SiC MOSFET device having low specific on resistance is described. The device has N+, P-well and JFET regions extended in one direction (Y-direction) and P+ and source contacts extended in an orthogonal direction (X-direction). The polysilicon gate of the device covers the JFET region and is terminated over the P-well region to minimize electric field at the polysilicon gate edge. In use, current flows vertically from the drain contact at the bottom of the structure into the JFET region and then laterally in the X direction through the accumulation region and through the MOSFET channels into the adjacent N+ region. The current flowing out of the channel then flows along the N+ region in the Y-direction and is collected by the source contacts and the final metal. Methods of making the device are also described. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/890981 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/456 (20130101) H01L 29/0696 (20130101) H01L 29/0869 (20130101) H01L 29/0878 (20130101) H01L 29/1095 (20130101) H01L 29/1608 (20130101) H01L 29/4238 (20130101) H01L 29/7802 (20130101) Original (OR) Class H01L 29/7827 (20130101) H01L 29/42356 (20130101) H01L 29/66068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693183 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Xiaolin Li (Richland, Washington); Jun Liu (Richland, Washington); Vincent L. Sprenkle (Richland, Washington) |
| ABSTRACT | A sodium-ion battery that includes an anode comprising hard carbon and lithium; and an electrolyte composition comprising an ether solvent and a sodium salt. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 14/683038 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/587 (20130101) H01M 10/05 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693343 | Post |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F. Post (Walnut Creek, California) |
| ABSTRACT | A geometric design of E-S generator motor electrodes mounted on the inner surface of a fiber-composite rotor is provided. The electrode configuration is able to sustain very high g levels. The rotor may be funned of carbon-fiber wound on top of an inner E car S-glass fiber composite core. The electrode design provides the needed area to satisfy the power requirements of the storage system and utilizes a stacked wedge-like electrode array that both solves the high-g problem and results in a doubling or tripling of the electrode area, relative to that of electrodes that conform to the inner cylindrical surface of the rotor. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 16/401994 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 14/00 (20130101) Dynamo-electric Machines H02K 7/025 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693661 | Hamlet |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jason Hamlet (Albuquerque, New Mexico) |
| ABSTRACT | Described herein are various technologies pertaining to extracting cryptographic keys from user behavioral biometrics, specifically keystroke dynamics. Such cryptographic keys can be used for, among other things, user authentication throughout computer sessions. Keystroke dynamics are timing data indicating when keys were pressed and when they were released. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/801646 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693811 | Lesartre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Gregg B. Lesartre (Fort Collins, Colorado); Norell Estella Menhusen (Fort Collins, Colorado); Darel Neal Emmot (Wellington, Colorado); David P. Hannum (Fort Collins, Colorado) |
| ABSTRACT | A system, includes a plurality of sub-queues. Each sub-queue is assigned to an age class of a sequence of age classes. A set of age thresholds divides the sub-queues. A queue manager places a received transaction into a sub-queue based on a comparison of an age of the received transaction to the set of age thresholds. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/146605 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/29 (20130101) H04L 47/39 (20130101) H04L 47/562 (20130101) H04L 47/564 (20130101) H04L 47/629 (20130101) H04L 47/6215 (20130101) H04L 47/6275 (20130101) H04L 49/254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694590 | Rios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Orlando Rios (Knoxville, Tennessee); William G. Carter (Oak Ridge, Tennessee); Zachary C. Sims (Johnson City, Tennessee); Lonnie J. Love (Knoxville, Tennessee); Phillip C. Chesser (Knoxville, Tennessee) |
| ABSTRACT | A method and apparatus for additive manufacturing that includes a material guide for directing a supply of working material and a plurality of rollers for advancing the working material. An electromagnetic heater is provided to heat and deposit molten working material as a new supply of working material is forced through the material guide. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484913 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/005 (20130101) B21C 29/04 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/115 (20130101) B22F 3/1055 (20130101) B22F 2003/1056 (20130101) B22F 2003/1056 (20130101) B22F 2202/07 (20130101) B22F 2202/07 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 13/01 (20130101) B23K 13/04 (20130101) B23K 2103/10 (20180801) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/118 (20170801) B29C 64/209 (20170801) B29C 64/336 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/16 (20130101) B29K 2105/0067 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/06 (20130101) H05B 6/14 (20130101) H05B 6/36 (20130101) H05B 6/40 (20130101) H05B 6/101 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10688560 | Gradl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Paul R. Gradl (Owens Cross Roads, Alabama); Adam C. Kimberlin (Huntsville, Alabama); Darrell Edwin Gaddy (Valhermoso Springs, Alabama); Roger Derek Moody (Cullman, Alabama) |
| ABSTRACT | A method and system are provided for mapping a melt pattern of material created during directed energy fabrication. An infrared camera and a video camera are provided to record images of the pattern of melted material. Each frame of the infrared camera's images is processed to generate a first map of pixels identifying pixels indicative of a highest temperature greater than or equal to a liquidus temperature of the meltable material. Each frame of the video camera's images is processed to generate a second map of pixels identifying pixels indicative of a highest temperature greater than or equal to the liquidus temperature of the meltable material. The first map of pixels and said second map of pixels are overlaid on each other wherein a third map of pixels is generated and is indicative of a hybrid image of the pattern of melted material. |
| FILED | Tuesday, March 21, 2017 |
| APPL NO | 15/465324 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) Original (OR) Class B22F 2003/1057 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0013 (20130101) B23K 15/0086 (20130101) B23K 26/032 (20130101) B23K 26/034 (20130101) B23K 26/342 (20151001) B23K 26/1224 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688714 | Bottiglio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rebecca Kramer Bottiglio (New Haven, Connecticut); Michelle Ching-Sum Yuen (New Haven, Connecticut) |
| ABSTRACT | Methods and systems suitable for fabricating multi-layer elastic electronic devices, and elastic electronic devices formed thereby. A method of fabricating an elastomer-based electronic device includes printing a first liquid material and then a second liquid material on a fabric substrate that comprises fibers. The first and second liquid materials are sequentially printed with a three-dimensional printer that directly prints the first liquid material onto the fabric substrate so that the first liquid material wicks through some of the fibers of the fabric substrate and forms a solid matrix of an elastomer-based composite that comprises the matrix and the fabric substrate, after which the three-dimensional printer directly prints the second liquid material on the elastomer-based composite to form a film thereon. The elastomer-based composite and film are electrical components of the elastomer-based electronic device. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 15/662762 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/209 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2021/00 (20130101) B29K 2913/00 (20130101) B29K 2995/0006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/752 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) G01B 7/22 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/16 (20130101) H05K 1/038 (20130101) H05K 1/095 (20130101) H05K 1/162 (20130101) H05K 1/167 (20130101) H05K 3/0011 (20130101) H05K 3/1241 (20130101) H05K 3/1283 (20130101) H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689986 | Ameri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Adminstrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Ali A. Ameri (Solon, Ohio); Vikram Shyam (Cleveland, Ohio) |
| ABSTRACT | A film cooled component is provided that includes a body having a cavity defined therein, wherein a coolant is supplied to the cavity cooling apertures having at least one channel defined on an inside surface. The coolant exits the cavity through the plurality of cooling apertures thereby providing a cooling effect to the body and the channel creates an air flow such that the air coolant moves towards the body upon exiting the plurality of cooling apertures. The film cooled component may include cooling apertures configured to reverse blow coolant air. |
| FILED | Tuesday, October 10, 2017 |
| APPL NO | 15/728941 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/202 (20130101) F05D 2260/2212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690227 | Hofmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Douglas C. Hofmann (Altadena, California); Brian H. Wilcox (La Canada, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention implement tailored metallic glass-based strain wave gears and strain wave gear components. In one embodiment, a method of fabricating a flexspline of a strain wave gear includes: forming a MG-based composition into a flexspline using one of a thermoplastic forming technique and a casting technique; where the forming of the MG-based composition results in a formed MG-based material; where the formed flexspline is characterized by: a minimum thickness of greater than approximately 1 mm and a major diameter of less than approximately 4 inches. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/214848 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 19/0036 (20130101) Alloys C22C 45/10 (20130101) Gearing F16H 49/001 (20130101) Original (OR) Class F16H 2049/003 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4948 (20150115) Y10T 29/49462 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690918 | Inman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A., AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jennifer A. Inman (Williamsburg, Virginia); Paul M. Danehy (Newport News, Virginia); Brian K. Perkins (Newport News, Virginia); Christopher J. Peters (Olivette, Missouri) |
| ABSTRACT | According to certain examples, a head-mounted apparatus includes a safety eyewear component and an optical display coupled to the safety eyewear component. The safety eyewear component is configured to be worn of a head of an operator and to block transmission of a laser light therethrough. The optical display is configured to receive data associated with the laser light and to display a visual representation of the laser light in a field of view of the operator. In other examples, an apparatus includes a display, a sensor, at least one processor and at least one memory storing computer-readable instructions that, when executed by the at least one processor, cause the apparatus to receive, from the sensor, data associated with a laser light, process the data, and provide an image to the display, such as a representation of the laser light. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832372 |
| ART UNIT | 2691 — Selective Visual Display Systems |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/022 (20130101) Optical Elements, Systems, or Apparatus G02B 5/20 (20130101) G02B 5/208 (20130101) G02B 27/017 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/014 (20130101) G02B 2027/0138 (20130101) G02B 2027/0141 (20130101) G02B 2027/0147 (20130101) G02B 2027/0178 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/104 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10691848 | Hunziker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Kenneth Joseph Hunziker (Issaquah, Washington); Jaffar Sher Iqbal (Seattle, Washington); Jenna Kristin Pang (Bellevue, Washington); Mostafa Rassaian (Bellevue, Washington) |
| ABSTRACT | A composite structure, such as a laminated composite panel, for example, comprises one or more layers or “plies” embedded in a matrix material or otherwise fixed together in an arrangement, commonly referred to as a “stack up.” Each material in the structure has a corresponding material failure model (MFM) defining the physical characteristics of that material. A ballistic threshold velocity computing device obtains the MFMs for each material in the composite structure, generates a predicted ballistic velocity threshold velocity for each MFM, and then generates a parametric model to compute a composite ballistic velocity threshold velocity for the composite structure. |
| FILED | Monday, February 19, 2018 |
| APPL NO | 15/898984 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/04 (20130101) Electric Digital Data Processing G06F 7/544 (20130101) G06F 30/20 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693210 | Chattopadhyay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Goutam Chattopadhyay (Pasadena, California); Imran Mehdi (South Pasadena, California); Choonsup Lee (La Palma, California); John J. Gill (La Crescenta, California); Cecile D. Jung-Kubiak (Pasadena, California); Nuria Llombart (Delft, Netherlands) |
| ABSTRACT | A set of antenna geometries for use in integrated arrays at terahertz frequencies are described. Two fabrication techniques to construct such antennas are presented. The first technique uses an advanced laser micro-fabrication, allowing fabricating advanced 3D geometries. The second technique uses photolithographic processes, allowing the fabrication of arrays on a single wafer in parallel. |
| FILED | Wednesday, April 24, 2013 |
| APPL NO | 13/869292 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 11/001 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 15/08 (20130101) H01Q 19/062 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49016 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693700 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/726037 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/3405 (20130101) Original (OR) Class H04L 27/3809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10694403 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/726065 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 15/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10688063 | Farese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); The United States Government as Represented by the Department of Veterans Affairs of General Counsel- PSG IV (024) (Washington, District of Columbia) |
| INVENTOR(S) | Robert Vito Farese (St. Petersburg, Florida); Mini Paliyath Sajan (Wesley Chapel, Florida) |
| ABSTRACT | Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD). |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/730423 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) Original (OR) Class A61K 31/341 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688130 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Saul A. Villeda (Lancaster, California); Joseph M. Castellano (San Mateo, California); Jinte Middeldorp (Utrecht, Netherlands); Martin S. Angst (Stanford, California); Jian Luo (Palo Alto, California) |
| ABSTRACT | Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention. |
| FILED | Friday, December 05, 2014 |
| APPL NO | 14/562401 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10688154 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jian Luo (Palo Alto, California); Anton Wyss-Coray (Palo Alto, California) |
| ABSTRACT | The present invention provides methods for preventing, attenuating neuronal damage or stimulating neuronal repair prior or following central nervous system injury. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687175 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class A61K 38/193 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689446 | Meza-Romero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Roberto Meza-Romero (Beaverton, Oregon); Gil Benedek (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ABSTRACT | Disclosed are recombinant CD74 polypeptides mutated relative to the naturally occurring CD74 polypeptides with improved properties such as binding of CD74 ligands such as MIF and RTL1000 as well as polynucleotides that encode the polypeptides, expression vectors comprising the polynucleotides, bacteria that include the expression vectors, and methods of making the recombinant polypeptides. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 15/629573 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/70539 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 2319/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690774 | Pearlman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Eric Joseph Sinagra (Bethel Park, Pennsylvania); Jonathan Aaron Duvall (Verona, Pennsylvania); Joshua D. Brown (Pittsburgh, Pennsylvania); Dianna Rae Stuckey (Butler, Pennsylvania); Tianyang Chen (Shanghai, China PRC); Ian Patrick McIntyre (Holland, Pennsylvania); Rory Alan Cooper (Gibsonia, Pennsylvania) |
| ABSTRACT | A pathway measurement system hereof includes a rigid frame and a mobility system attached to the frame. The mobility system includes at least one movable element which is adapted to contact a surface of a pathway via which the frame may be moved relative to the pathway. The pathway measurement system further includes at least one sensor adapted to measure at least one characteristic of a pathway. The pathway measurement system has a first mode of operation in which the mobility system moves the frame along the pathway to move the at least one sensor relative to the pathway. The at least one sensor is connected to the pathway system such that a distance between the at least one sensor and an axis of rotation of one of the moveable elements remains constant in the first mode of operation. In general, the at least one sensor is isolated from any compliance or suspension system. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111921 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 7/04 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4813 (20130101) G01S 17/42 (20130101) Original (OR) Class G01S 17/86 (20200101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10689267 | Essandoh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Essandoh (Philadelphia, Pennsylvania); Rafael A. Garcia (Dresher, Pennsylvania) |
| ABSTRACT | Disclosed are methods to remove organic and/or inorganic compounds (e.g., contaminants) from water containing organic and/or inorganic compounds, involving contacting the water with an effective organic and/or inorganic compounds removing amount of hemoglobin/Fe3O4 composite where the compounds in the water adsorb onto the hemoglobin/Fe3O4 composite, and removing (e.g., using a magnet since the composite is magnetic) the hemoglobin/Fe3O4 composite from the water. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 15/423955 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/24 (20130101) B01J 20/223 (20130101) B01J 20/3085 (20130101) B01J 20/28009 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/286 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 2101/20 (20130101) C02F 2101/306 (20130101) C02F 2101/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689633 | Daniell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Winter Park, Florida) |
| ABSTRACT | Disclosed herein are materials useful for degrading plant biomass material. In exemplary embodiments, the plant material comprises one or more enzymes that are expressed in plants and/or bacteria. Specifically exemplified herein are plant degrading enzymes expressed in chloroplasts. The chloroplast expressed enzymes may be provided as cocktails for use in conjunction with conventional methods of converting biomass into biofuels, such as cellulosic ethanol. In other exemplary embodiments, methods and materials are disclosed for degrading mannans. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 13/659396 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 9/2494 (20130101) C12N 15/8214 (20130101) C12N 15/8242 (20130101) C12N 15/8257 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/12 (20130101) Enzymes C12Y 302/01078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690592 | Settles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Andrew M. Settles (Gainesville, Florida); Jeffery Lynn Gustin, II (Gainesville, Florida) |
| ABSTRACT | Methods for sorting haploid maize kernels in haploid induction crosses are provided. A method of sorting haploid kernels can include capturing near-infrared (NIR) spectra and applying a general multivariate statistical model to the acquired NIR spectra to discriminate haploid kernels from diploid-hybrid kernels mixed therein. NIR spectra can be collected on a single kernel using a high-throughput apparatus such that the amount of time required to analyze individual kernels can be significantly reduced in comparison to existing NIR technology and in comparison to traditional manual sorting. |
| FILED | Tuesday, March 14, 2017 |
| APPL NO | 16/084422 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/342 (20130101) B07C 5/3425 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) Original (OR) Class G01N 21/3563 (20130101) G01N 2201/129 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10687704 | Hastings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Todd Hastings (Lexington, Kentucky); E. Britt Brockman (Louisville, Kentucky); Ingrid L. St. Omer (Lexington, Kentucky); John C. Wright (Louisville, Kentucky) |
| ASSIGNEE(S) | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky); BROCKMAN HOLDINGS LLC (Louisville, Kentucky) |
| INVENTOR(S) | Jeffrey Todd Hastings (Lexington, Kentucky); E. Britt Brockman (Louisville, Kentucky); Ingrid L. St. Omer (Lexington, Kentucky); John C. Wright (Louisville, Kentucky) |
| ABSTRACT | A system for determination of intraocular pressure includes: an intraocular pressure sensor; a light source illuminating the sensor with one or more wavelengths of light; and a detector that measures emitted light from the sensor. The sensor includes a substrate member, a spacer member, and a flexible membrane, which define a sealed cavity. The flexible membrane moves in response to intraocular pressure changes. A device for measuring intraocular pressure includes: the sensor; an anchoring member attached to the sensor for immobilizing the sensor in an eye; and a protective member attached to the anchoring member and covering the sensor to prevent contact between the flexible membrane and the eye. A method for determination of intraocular pressure includes: placing the sensor in an eye; illuminating, with a light source, the sensor with one or more wavelengths of light; and detecting, with a detector, a resultant light that contains information about intraocular pressure. |
| FILED | Thursday, December 30, 2010 |
| APPL NO | 12/982110 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/165 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10689433 | Leighton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crystal Bioscience Inc. (San Diego, California) |
| ASSIGNEE(S) | CRYSTAL BIOSCIENCE INC. (San Diego, California) |
| INVENTOR(S) | Philip A. Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California) |
| ABSTRACT | A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/723075 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Peptides C07K 16/00 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693178 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jitendra Kumar (Centerville, Ohio); Priyanka Bhattacharya (Beavercreek, Ohio); Guru Subramanyam (Dayton, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF DAYTON (Dayton, Ohio) |
| INVENTOR(S) | Jitendra Kumar (Centerville, Ohio); Priyanka Bhattacharya (Beavercreek, Ohio); Guru Subramanyam (Dayton, Ohio) |
| ABSTRACT | Lithium sulfur batteries are described, especially ones that are flexible for wearing about an appendage of a wearer. Such batteries have a lithium metal anode, a sulfur cathode comprising sulfur, a conductive carbon, a lithium supertonic solid-state conductor, and a dendritic or hyperbranched polymer binder, an electrolyte layer between the lithium metal anode and the sulfur cathode, and a current collector positioned on the sulfur cathode opposite the electrolyte layer. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956043 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/382 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/626 (20130101) H01M 4/663 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 10/0436 (20130101) H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2220/30 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10690562 | Rieker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Gregory B. Rieker (Boulder, Colorado); Kuldeep Prasad (Vienna, Virginia); Caroline B. Alden (Boulder, Colorado); Sean C. Coburn (Longmont, Colorado); Robert J. Wright (Boulder, Colorado) |
| ABSTRACT | A system for detecting gas leaks and determining their location and size. A data gathering portion of the system utilizes a chosen geometrical configuration to collect path-integrated spectroscopic data over multiple paths around an area. A processing portion of the system applies a transport model together with meteorological data of the area to generate an influence function of possible leak locations on gas detector measurement paths, and applies an inversion model to the influence function, prior data, and the spectroscopic data to generate gas source size and location. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 16/343363 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) G01M 3/16 (20130101) Original (OR) Class G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0027 (20130101) G01N 33/0062 (20130101) Meteorology G01W 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10692980 | Slack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
| ASSIGNEE(S) | CRYSTAL IS, INC. (Green Island, New York) |
| INVENTOR(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
| ABSTRACT | Fabrication of doped AlN crystals and/or AlGaN epitaxial layers with high conductivity and mobility is accomplished by, for example, forming mixed crystals including a plurality of impurity species and electrically activating at least a portion of the crystal. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/055228 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/00 (20130101) C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/2258 (20130101) H01L 21/02579 (20130101) H01L 29/207 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 33/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10689814 | Azizinamini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Atorod Azizinamini (Miramar, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Atorod Azizinamini (Miramar, Florida) |
| ABSTRACT | A modular railing system for on-site assembly of a railing system along a roadway is provided. The modular railing system can include a deck with an edge beam along one side and a railing that can be attached to the edge beam. Attachment of the railing to the edge beam raises the joint between the deck and the railing to inhibit water seepage into the joint. In a specific embodiment, UHPC can be used to attach the railing to the edge beam. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263163 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Construction of Bridges, or Viaducts; Assembly of Bridges E01D 19/10 (20130101) Original (OR) Class E01D 19/103 (20130101) Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 15/083 (20130101) E01F 15/088 (20130101) E01F 15/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10690776 | McMilin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Emily McMilin (Palo Alto, California); David S. De Lorenzo (Palo Alto, California); Per K. Enge (Mountain View, California); Dennis M. Akos (Boulder, Colorado) |
| ABSTRACT | There is provided an apparatus comprising an antenna (105) configured to receive a signal from a global navigation satellite system, wherein the antenna includes a first feed and a second feed; a hybrid coupler (110) including a first hybrid input, a second hybrid input, a first hybrid output, a second hybrid output, and wherein the first hybrid output is shifted in phase by 90 degrees relative to the second hybrid output; a variable phase shifter (150) including a shifter input and a shifter output, hybrid output; and a combiner (155) including a first combiner input, a second combiner input, and a combiner output, wherein the first combiner input is coupled to the shifter output, and the second combiner input is coupled to the second hybrid output, and wherein the combiner output is provided to detection circuitry (197). |
| FILED | Friday, September 04, 2015 |
| APPL NO | 15/507860 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/21 (20130101) G01S 19/36 (20130101) G01S 19/215 (20130101) Original (OR) Class Secret Communication; Jamming of Communication H04K 3/28 (20130101) H04K 3/90 (20130101) H04K 3/228 (20130101) H04K 2203/22 (20130101) H04K 2203/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10693787 | Schneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Timo Schneider (Zurich, Switzerland); Keith D. Underwood (Powell, Tennessee); Mario Flajslik (Hopkinton, Massachusetts); Sayantan Sur (Portland, Oregon); James Dinan (Hudson, Massachusetts) |
| ABSTRACT | Techniques are disclosed to throttle bandwidth imbalanced data transfers. In some examples, an example computer-implemented method may include splitting a payload of a data transfer operation over a network fabric into multiple chunk get operations, starting the execution of a threshold number of the chunk get operations, and scheduling the remaining chunk get operations for subsequent execution. The method may also include executing a scheduled chunk get operation in response determining a completion of an executing chunk get operation. In some embodiments, the chunk get operations may be implemented as triggered operations. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686264 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/10 (20130101) Original (OR) Class H04L 47/125 (20130101) H04L 49/3072 (20130101) H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10693818 | Underwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | Keith D. Underwood (Powell, Tennessee); Charles A. Giefer (Seattle, Washington) |
| ABSTRACT | Packet tracking techniques for communication networks are described. In an example embodiment, an apparatus may comprise circuitry, a tracking component for execution by the circuitry to, in response to a request of an initiator device to establish a packet transfer session, determine whether tracking information for the packet transfer session can be locally maintained and in response to a determination that the tracking information for the packet transfer session cannot be locally maintained, identify one or more tracking parameters for retention at the initiator device, and a communication component for execution by the circuitry to send an acceptance message to grant the request of the initiator device to establish the packet transfer session, the acceptance message to indicate a request for retention of the one or more tracking parameters. Other embodiments are described and claimed. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189323 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 49/9057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10692352 | Dougall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Luis Dougall (Washington, District of Columbia); Jacob James Rath (Washington, District of Columbia); Blaise Carlson Curtis (Washington, District of Columbia); Liam Christian Otto (Washington, District of Columbia); Frederick John McClimans (Washington, District of Columbia); Matthew Tyler Williams (Washington, District of Columbia); Thomas Carsten Rodzewicz (Washington, District of Columbia); Ronald Adrezin (East Lyme, Connecticut); Michael Plumley (Washington, District of Columbia) |
| ABSTRACT | A buoy corrosion detection system includes a buoy having a double hull section in which the outer hull is designed to corrode and fail prior to the rest of the hull. The double hull section is positioned at the waterline, which is the area most prone to corrosion. As the outer hull corrodes, water passes through the hull and is detected by a moisture detector. The moisture detector then relays a signal that water has entered through the hull, and a signaling circuit then sends a communication signal to the user indicating that the buoy has corrosion. The buoy corrosion detection system leads to an “as-needed” maintenance cycle for buoys. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/387280 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/04 (20130101) B63B 2022/006 (20130101) B63B 2203/00 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10692405 | Bonnell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia) |
| ABSTRACT | A transport equipment label bracket that can be used during tracking and/or locating of delivery item(s) (e.g. mail) positioned on delivery-item transport equipment such as a delivery-item transport cart. The bracket can have positioned thereon a permanent first identifier and a permanent second identifier, wherein the second identifier includes a radio-frequency identification (RFID) chip. The bracket can further include a placard mount for temporarily positioning a placard such as a delivery-item transport equipment label. The placard and either/both of the first identifier and the second identifier can be scanned to associate or conjoin the placard with the RFID chip as represented in a computerized delivery-item-tracking system. Thereafter, the RFID chip can be scanned to identify a location of the placard and thus the location of the delivery-item transport cart. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/132073 |
| ART UNIT | 3638 — Static Structures, Supports and Furniture |
| CURRENT CPC | Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/02 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 7/18 (20130101) Original (OR) Class G09F 21/00 (20130101) G09F 2007/1847 (20130101) G09F 2007/1856 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 23, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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