FedInvent™ Patents
Patent Details for Tuesday, July 07, 2020
This page was updated on Monday, March 27, 2023 at 06:07 AM GMT
Department of Health and Human Services (HHS)
| US 10702152 | Crisco, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | Riddell, Inc. (Rosemont, Illinois) |
| ASSIGNEE(S) | Riddell, Inc. (Des Plaines, Illinois) |
| INVENTOR(S) | Joseph J. Crisco, III (Providence, Rhode Island); Richard M. Greenwald (Norwich, Vermont); Jeffrey J. Chu (Quechee, Vermont) |
| ABSTRACT | The invention relates to a protective sports equipment system with real-time impact monitoring of a player engaged in a contact sporting activity. The system includes a protective equipment assembly and an interface liner disposed within a padding assembly of the protective equipment assembly. The interface liner has a sensing and control unit with an array of sensors to detect impact data, a processor to determine an impact result, and a transmitter to transmit the impact result. The system also includes a remote unit that receives and displays the transmitted impact result. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483529 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Hats; Head Coverings A42B 3/046 (20130101) A42B 3/125 (20130101) Diagnosis; Surgery; Identification A61B 5/0004 (20130101) Original (OR) Class A61B 5/11 (20130101) A61B 5/742 (20130101) A61B 5/1121 (20130101) A61B 5/4076 (20130101) A61B 5/6803 (20130101) A61B 5/6814 (20130101) A61B 5/7246 (20130101) A61B 5/7475 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 71/06 (20130101) A63B 71/10 (20130101) A63B 2208/12 (20130101) A63B 2220/40 (20130101) A63B 2230/60 (20130101) A63B 2243/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702244 | O'Reilly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meaghan Anne O'Reilly (Toronto, Canada); Kullervo Henrik Hynynen (Toronto, Canada) |
| ASSIGNEE(S) | SUNNYBROOK RESEARCH INSTITUTE (Toronto, Canada) |
| INVENTOR(S) | Meaghan Anne O'Reilly (Toronto, Canada); Kullervo Henrik Hynynen (Toronto, Canada) |
| ABSTRACT | A system and method for controlling the delivery of ultrasound energy to a subject is provided. In particular, such a system and method are capable of safely disrupting the blood-brain barrier. Ultrasound energy is delivered to produce cavitation of an ultrasound contrast agent at a selected pressure value. An acoustic signal is acquired following cavitation, from which a signal spectrum is produced. The signal spectrum is analyzed for the presence of harmonics, such as subharmonics or ultraharmonics. When subharmonics or ultraharmonics are present, the pressure value is decreased for subsequent sonications. If a previous sonication resulted in no subharmonics or ultraharmonics being generated, then the pressure value may be increased. In this manner, the blood-brain barrier can be advantageously disrupted while mitigating potentially injurious effects of the sonication. |
| FILED | Friday, June 29, 2012 |
| APPL NO | 13/538350 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) Original (OR) Class A61B 8/0808 (20130101) A61B 8/4488 (20130101) A61B 2017/00106 (20130101) A61B 2090/374 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) A61N 2007/0091 (20130101) A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702485 | Zebala |
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| FUNDED BY |
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| APPLICANT(S) | John A. Zebala (Issaquah, Washington) |
| ASSIGNEE(S) | Syntrix Biosystems Inc. (Auburn, Washington) |
| INVENTOR(S) | John A. Zebala (Issaquah, Washington) |
| ABSTRACT | There is disclosed a composition for oral administration of O-desmethyltramadol. Compositions are also provided that are effective for overcoming resistance to tramadol in patients. |
| FILED | Sunday, July 08, 2012 |
| APPL NO | 13/543883 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/28 (20130101) A61K 9/0053 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/2866 (20130101) A61K 31/135 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702497 | Worth et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Randall G. Worth (Toledo, Ohio); Glenn R. Westphal (Toledo, Ohio); Brenton R. Keeley (Toledo, Ohio); Leah M. Wuescher (Toledo, Ohio) |
| ABSTRACT | Uses of acyl-homoserine lactone compounds are described. In particular, uses of acyl-homoserine lactone compounds as anti-thrombotic agents, to inhibit platelets from becoming hypersensitive, and/or to prevent thrombosis, are described. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217527 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702498 | Shoichet et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); FRIEDRICH-ALEXANDER-UNIVERSITÃT ERLANGEN-NÜRNBERG (Erlangen, Germany); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NÜRNBERG (Erlangen, Germany); THE BOARD OF TRUSTEES OFTHE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Brian K. Shoichet (Kentfield, California); Henry Lin (Dresher, Pennsylvania); Peter Gmeiner (Buckenhof, Germany); Aashish Manglik (Menlo Park, California); Brian Kobilka (Palo Alto, California); Bryan L. Roth (Durham, North Carolina); Daniela Gisela Dengler (Erlangen, Germany) |
| ABSTRACT | Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity. |
| FILED | Thursday, June 30, 2016 |
| APPL NO | 15/743079 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/165 (20130101) A61K 31/381 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) Acyclic or Carbocyclic Compounds C07C 275/24 (20130101) C07C 275/26 (20130101) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 207/452 (20130101) C07D 233/16 (20130101) C07D 249/04 (20130101) C07D 295/125 (20130101) C07D 333/16 (20130101) C07D 333/20 (20130101) C07D 333/58 (20130101) C07D 401/12 (20130101) C07D 409/12 (20130101) C07D 471/04 (20130101) C07D 495/04 (20130101) C07D 498/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702501 | Buynak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | John D. Buynak (Dallas, Texas); Noora M. S. A. Al-Kharji (Richardson, Texas); Weirui Chai (Chicago, Illinois); Thu Q. Nguyen (North Richland Hills, Texas); Maha Alqurafi (Dallas, Texas); Kyle Rohde (Orlando, Florida); Rashmi Gupta (Lake Mary, Florida) |
| ABSTRACT | The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: R1 is H or CH3 R2 is not H, and is CH3, or C1-C6 straight chain, or branched alkyl, or C3-C6 cycloalkyl group, or unsaturated alkenyl, including C═CH2; R3 is H, CH3, or a C1-C6 alkyl or cycloalkyl group, a heteroatom-substituted alkyl; and R4 is a C1 to C6 alkyl, or substituted alkyl group, especially including substituents which possess positive charge, or a hydroxyl group; or R4 is an SRa, where Ra is an unsubstituted C1 to C6 alkyl group, a substituted C1 to C6 alkyl group, or a functional group that is positively charged, or which bears a positive charge when in aqueous solution at pH 7; or R4 is a CH2ORb, where Rb=C1 to C6 alkyl or substituted alkyl groups, substituted or unsubstituted aryl, or a heteroaryl groups. |
| FILED | Tuesday, June 12, 2018 |
| APPL NO | 16/006374 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 477/00 (20130101) C07D 477/04 (20130101) C07D 477/06 (20130101) C07D 477/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702506 | Verkman et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alan S. Verkman (Oakland, California); Peter M. Haggie (Oakland, California); Onur Cil (Oakland, California) |
| ABSTRACT | Provided herein are small molecule inhibitors of pendrin. More specifically, the small molecules disclosed herein may be used to inhibit pendrin-mediated anion exchange. These small molecules may be used for treatment of diseases and disorders that are treatable by inhibiting pendrin, such as cystic fibrosis, rhinitis, chronic rhinosinusitis, exposure to an industrial toxin, certain viral infections, certain bacterial infections, and chronic obstructive pulmonary disease. The small molecules may further be used to potentiate a diuretic effect of a diuretic compound. The small molecules may additionally be used to treat hypertension or thyroid conditions. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 16/079019 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/04 (20180101) A61P 31/12 (20180101) Heterocyclic Compounds C07D 409/04 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702514 | Lefcort et al. |
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| FUNDED BY |
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| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); N-GENE RESEARCH LABORATORIES, INC. (New York, New York) |
| ASSIGNEE(S) | N-GENE RESEARCH LABORATORIES, INC. (New York, New York); MONTANA STATE UNIVERSITY (Bozeman, Montana) |
| INVENTOR(S) | Frances Brenda Lefcort (Bozeman, Montana); Michael Jay Brownstein (Rockville, Maryland) |
| ABSTRACT | Disclosed is the use of O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime (BGP15), its tautomers, enantiomers and pharmaceutically acceptable salts thereof for the treatment of Familial Dysaustonomia. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637257 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702521 | Widdowson |
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| FUNDED BY |
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| APPLICANT(S) | GlaxoSmithKline Intellectual Property Development Limited (Brentford, Middlesex, United Kingdom) |
| ASSIGNEE(S) | GlaxoSmithKline Intellectual Property Development Limited (, United Kingdom) |
| INVENTOR(S) | Katherine Louisa Widdowson (San Diego, California) |
| ABSTRACT | The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions. |
| FILED | Thursday, August 20, 2015 |
| APPL NO | 15/505715 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) A61K 31/542 (20130101) A61K 31/554 (20130101) A61K 31/4375 (20130101) A61K 31/4545 (20130101) A61K 31/4725 (20130101) A61K 31/4985 (20130101) Original (OR) Class A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702527 | Hammerman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Peter Hammerman (Newton, Massachusetts); Kwok-kin Wong (Arlington, Massachusetts); Nathanael S. Gray (Boston, Massachusetts) |
| ABSTRACT | The present disclosure provides combination therapy of a transcription inhibitor and a kinase inhibitor. The combination of the transcription inhibitor and the kinase inhibitor may be useful in treating and/or preventing in a subject a proliferative disease, such as proliferative a disease that is resistant to the transcription inhibitor alone or the kinase inhibitor alone. In certain embodiments, the proliferative disease is a cancer. The combination of the transcription inhibitor and the kinase inhibitor is expected to be synergistic. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/735532 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/53 (20130101) A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/4162 (20130101) A61K 31/5517 (20130101) A61K 31/5517 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702559 | Lesser et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Cammie Lesser (Cambridge, Massachusetts); Analise Reeves (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are compositions and methods relating to engineered bacteria which have a modified Type 3 Secretion System (T3SS) which permits them to deliver proteins to the extracellular space (e.g., as opposed to the intracellular space of a target cell as done with a wild-type T3SS). In some embodiments, the engineered bacteria comprise a transgenic T3SS. In some embodiments, the delivered protein is non-native or transgenic with respect to the engineered bacteria. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 16/075410 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/70 (20130101) A61K 35/74 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 35/00 (20180101) Peptides C07K 14/25 (20130101) C07K 14/33 (20130101) C07K 14/195 (20130101) C07K 14/245 (20130101) C07K 14/255 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/74 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702567 | Newman et al. |
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| FUNDED BY |
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| APPLICANT(S) | PHOENIX BIOTECHNOLOGY, INC. (San Antonio, Texas) |
| ASSIGNEE(S) | PHOENIX BIOTECHNOLOGY, INC. (San Antonio, Texas) |
| INVENTOR(S) | Robert A. Newman (Surry, Maine); Otis C. Addington (San Antonio, Texas) |
| ABSTRACT | A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes. |
| FILED | Wednesday, May 29, 2019 |
| APPL NO | 16/424902 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/7048 (20130101) A61K 36/24 (20130101) Original (OR) Class A61K 2236/37 (20130101) A61K 2236/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702574 | Soliman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Christopher So (Henderson, Nevada); Howard P. Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone. |
| FILED | Saturday, February 11, 2017 |
| APPL NO | 15/430449 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 47/60 (20170801) A61K 47/551 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702586 | Frey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Los Angeles (Los Angeles, California) |
| ASSIGNEE(S) | Children's Hospital Los Angeles (Los Angeles, California) |
| INVENTOR(S) | Mark R. Frey (Glendale, California); Michael Schumacher (Glendale, California) |
| ABSTRACT | Provided herein are methods and compositions for treating disease-states associated with presence of increased number of ErbB4+ pro-inflammatory macrophages in a subject in need thereof. The methods include providing an activator of ErbB4 and administering a therapeutically effective amount of the activator to the subject. The compositions include an activator of ErbB4. In one embodiment, the activation of ErbB4 is Neuregulin-4. |
| FILED | Tuesday, September 27, 2016 |
| APPL NO | 15/764239 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1883 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702589 | Kohtz |
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| FUNDED BY |
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| APPLICANT(S) | Ann and Robert H. Lurie Children's Hospital of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Jhumku D. Kohtz (Chicago, Illinois) |
| ABSTRACT | The present disclosure provides the use of Akr1b8, an agonist of Akr1b8, Akr1B10, or an agonist of Akr1B10 in methods and compositions for the treatment of neurological disorders and stress-induced conditions. Methods of increasing the levels of 5Thr3a on neuronal cells is also provided by contacting the neuronal cells with Akr1b8, an agonist of Akr1b8, Akr1B10, or an agonist of Akr1B10. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724921 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) A61K 38/443 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Enzymes C12Y 101/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702614 | Dadachova et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ekaterina Dadachova (Mahopac, New York); Claudia Gravekamp (New York, New York); Arturo Casadevall (New York, New York) |
| ASSIGNEE(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| INVENTOR(S) | Ekaterina Dadachova (Mahopac, New York); Claudia Gravekamp (New York, New York); Arturo Casadevall (New York, New York) |
| ABSTRACT | A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides so as to treat the tumor in the subject, or so as to reduce or prevent metastasis of the tumor in the subject. Radiobacteria-containing compositions and pharmaceutical compositions are also provided. |
| FILED | Friday, February 03, 2012 |
| APPL NO | 13/985087 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702735 | Nelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUTech Ventures (Lincoln, Nebraska); MADONNA REHABILITATION HOSPITAL (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska); Madonna Rehabilitation Hospital (Lincoln, Nebraska) |
| INVENTOR(S) | Carl A. Nelson (Lincoln, Nebraska); Cale J. Stolle (Lincoln, Nebraska); Judith M. Burnfield (Lincoln, Nebraska); Thad W. Buster (Gretna, Nebraska); Bernadette J. McCrory (Seward, Nebraska) |
| ABSTRACT | An elliptical system is disclosed having a crank assembly configured to be adjusted in length to accommodate users having varying gaits. In some embodiments, the crank assembly includes a crank and an axle connection bracket that is slidably adjustable with respect to the crank. For example, the crank assembly can include a crank link having a longitudinal body, where the longitudinal body is connected to the crank at one end and includes a longitudinal slot slidably coupled with the axle connection bracket. The axle connection bracket is configured to slide through a plurality of positions along the longitudinal body. In some embodiments, the crank assembly further includes a screw for adjusting the axle connection bracket with respect to the crank, where the screw can cause the axle connection bracket to slide through one or more positions of the plurality of positions when the screw is turned. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/560541 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/0059 (20151001) A63B 21/00069 (20130101) A63B 21/0085 (20130101) A63B 21/00181 (20130101) A63B 21/225 (20130101) A63B 22/001 (20130101) A63B 22/0015 (20130101) Original (OR) Class A63B 22/0664 (20130101) A63B 24/0062 (20130101) A63B 24/0087 (20130101) A63B 2022/067 (20130101) A63B 2024/009 (20130101) A63B 2208/12 (20130101) A63B 2225/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702858 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Bo Xu (Louisville, Kentucky); Zhichao Lu (Louisville, Kentucky); Gerald B. Hammond (Shelbyville, Kentucky) |
| ABSTRACT | Some embodiments of the invention include inventive catalysts (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions comprising the inventive catalysts. Some embodiments include methods of using the inventive catalysts (e.g., in hydrofluorination of an organic compound). Further embodiments include methods for making the inventive catalysts. Additional embodiments of the invention are also discussed herein. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/214793 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/055 (20130101) Original (OR) Class B01J 31/00 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 5/00 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 39/00 (20130101) Acyclic or Carbocyclic Compounds C07C 17/087 (20130101) C07C 17/087 (20130101) C07C 19/14 (20130101) C07C 29/62 (20130101) C07C 29/62 (20130101) C07C 29/62 (20130101) C07C 31/38 (20130101) C07C 35/48 (20130101) C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 47/575 (20130101) C07C 49/687 (20130101) C07C 49/693 (20130101) C07C 51/363 (20130101) C07C 51/363 (20130101) C07C 62/20 (20130101) C07C 67/287 (20130101) C07C 67/287 (20130101) C07C 67/287 (20130101) C07C 67/287 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/63 (20130101) C07C 69/65 (20130101) C07C 69/74 (20130101) C07C 69/78 (20130101) C07C 201/12 (20130101) C07C 201/12 (20130101) C07C 201/12 (20130101) C07C 205/37 (20130101) C07C 205/57 (20130101) C07C 213/08 (20130101) C07C 213/08 (20130101) C07C 217/84 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/54 (20130101) C07C 303/30 (20130101) C07C 303/30 (20130101) C07C 303/34 (20130101) C07C 309/73 (20130101) C07C 2601/02 (20170501) C07C 2601/14 (20170501) C07C 2601/16 (20170501) C07C 2602/28 (20170501) Heterocyclic Compounds C07D 207/34 (20130101) C07D 209/50 (20130101) C07D 215/227 (20130101) C07D 277/56 (20130101) C07D 307/68 (20130101) C07D 333/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703698 | Katzenellenbogen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | John A. Katzenellenbogen (Urbana, Illinois); Benita Katzenellenbogen (Urbana, Illinois); Sung Hoon Kim (Champaign, Illinois); Zeynep Madak-Erdogan (Champaign, Illinois); Philip Shaul (Richardson, Texas) |
| ABSTRACT | Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 16/067676 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 39/06 (20130101) C07C 39/12 (20130101) C07C 39/14 (20130101) C07C 39/17 (20130101) Original (OR) Class C07C 39/23 (20130101) C07C 39/42 (20130101) C07C 39/367 (20130101) C07C 43/196 (20130101) C07C 49/733 (20130101) C07C 49/755 (20130101) C07C 57/38 (20130101) C07C 235/34 (20130101) C07C 255/47 (20130101) C07C 2601/14 (20170501) C07C 2602/08 (20170501) C07C 2602/10 (20170501) C07C 2603/74 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703708 | Guerard et al. |
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| FUNDED BY |
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| APPLICANT(S) | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (Paris, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); UNIVERSITE DE NANTES (Nantes, France); UNIVERSITE D'ANGERS (Angers, France); THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (Paris, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); UNIVERSITE DE NANTES (Nantes, France); UNIVERSITE D'ANGERS (Angers, France); THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| INVENTOR(S) | François Guerard (Nantes, France); Jean-François Gestin (Nantes, France); Martin W. Brechbiel (Bethesda, Maryland); Yong-Sok Lee (Bethesda, Maryland) |
| ABSTRACT | The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene. |
| FILED | Thursday, November 24, 2016 |
| APPL NO | 15/777828 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 59/008 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 17/361 (20130101) C07C 17/361 (20130101) C07C 25/24 (20130101) C07C 25/24 (20130101) C07C 29/10 (20130101) C07C 29/10 (20130101) C07C 29/58 (20130101) C07C 29/58 (20130101) C07C 29/62 (20130101) C07C 29/62 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 41/18 (20130101) C07C 41/18 (20130101) C07C 43/225 (20130101) C07C 43/225 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/76 (20130101) C07C 201/12 (20130101) Original (OR) Class C07C 201/12 (20130101) C07C 205/11 (20130101) C07C 247/10 (20130101) C07C 247/16 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/50 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703737 | Menick et al. |
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| FUNDED BY |
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| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| INVENTOR(S) | Donald R. Menick (Isles of Palms, South Carolina); Chung-Jen James Chou (Mt. Pleasant, South Carolina); Daniel Herr (Johns Island, South Carolina); Xiaoyang Li (Charleston, South Carolina) |
| ABSTRACT | The present invention relates to histone deacetylase inhibitors, and to pharmaceutical compositions comprising the compounds, useful for the treatment of ischemia-reperfusion injury and for cardioprotection. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/351809 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Heterocyclic Compounds C07D 311/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703743 | Spiegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); Christopher Parker (Medina, Ohio) |
| ABSTRACT | The present invention is directed to new bifunctional compounds and methods for treating HIV infections. The bifunctional small molecules, generally referred to as ARM-HI's, function through orthogonal pathways, by inhibiting the gp120-CD4 interaction, and by recruiting anti-DNP antibodies to gp120-expressing cells, thereby preventing cell infection and spread of HIV. It has been shown that ARM-HI's bind to gp120 and gp-120 expressing cells competitively with CD4, thereby decreasing viral infectivity as shown by an MT-2 cell assay, the binding leading to formation of a ternary complex by recruiting anti-DNP antibodies to bind thereto, the antibodies present in the ternary complex promoting the complement-dependent destruction of the gp120-expressing cells. Compounds and methods are described herein. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037678 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703746 | Boxer et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE (Bethesda, Maryland); THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Matthew Brian Boxer (New Market, Maryland); Jason Matthew Rohde (Poolesville, Maryland); Rajan Pragani (Gaithersburg, Maryland); Li Liu (Germantown, Maryland); Mindy Irene Emily Davis (Rockville, Maryland); Kyle Ryan Brimacombe (Bethesda, Maryland); Min Shen (Boyds, Maryland); Anton Simeonov (Bethesda, Maryland); Surendra Karavadhi (Gaithersburg, Maryland); Daniel Jason Urban (Rockville, Maryland); Ajit Jadhav (Chantilly, Virginia); Xiaodong Wang (Chapel Hill, North Carolina); Andrew Louis McIver (Durham, North Carolina) |
| ABSTRACT | Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X1, X2, R1-4 and R13-18 are disclosed herein. The compounds are useful for treating cancer disorders, especially those involving mutant IDH1 enzymes. Pharmaceutical compositions containing compounds of Formula I or Formula II and methods of treatment comprising administering compounds of Formula I and Formula II are also disclosed. |
| FILED | Tuesday, December 22, 2015 |
| APPL NO | 15/538570 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/496 (20130101) A61K 31/499 (20130101) A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/4704 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 213/82 (20130101) C07D 215/22 (20130101) C07D 215/54 (20130101) C07D 215/227 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 413/04 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) Original (OR) Class C07D 417/14 (20130101) C07D 451/02 (20130101) C07D 471/04 (20130101) C07D 471/14 (20130101) C07D 487/08 (20130101) C07D 487/10 (20130101) C07D 491/048 (20130101) C07D 491/052 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703747 | Thatcher et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illnois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Directors of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gregory R. Thatcher (Urbana, Illinois); Rui Xiong (Urbana, Illinois); Yunlong Lu (Urbana, Illinois); Jiong Zhao (Urbana, Illinois); Debra A. Tonetti (Urbana, Illinois) |
| ABSTRACT | This invention is benzothiophene-based selective mixed estrogen receptor downregulators and their compositions and uses to treat estrogen-related disorders. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393258 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 5/24 (20180101) Heterocyclic Compounds C07D 333/00 (20130101) C07D 333/56 (20130101) C07D 333/60 (20130101) C07D 413/10 (20130101) C07D 417/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703784 | Sette et al. |
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| FUNDED BY |
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| APPLICANT(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (La Jolla, California) |
| ASSIGNEE(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (La Jolla, California) |
| INVENTOR(S) | Alessandro Sette (La Jolla, California); Cecilia Arlehamm (Del Mar, California); Bjoern Peters (San Diego, California); Howard Grey (La Jolla, California); John Sidney (San Diego, California) |
| ABSTRACT | The present invention relates to M. tuberculosis proteins and peptides, and subsequences, portions or modifications thereof and methods and compounds comprising the same for eliciting, stimulating, inducing, promoting, increasing, or enhancing an anti-M. tuberculosis immune response in a subject. |
| FILED | Monday, October 01, 2012 |
| APPL NO | 13/632281 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/04 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703785 | Walensky et al. |
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| FUNDED BY |
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| APPLICANT(S) | Loren D. Walensky (Newton, Massachusetts); Ruben Carrasco (Brookline, Massachusetts); Gregory H. Bird (Pelham, New Hampshire) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Newton, Massachusetts); Ruben Carrasco (Brookline, Massachusetts); Gregory H. Bird (Pelham, New Hampshire) |
| ABSTRACT | The invention provides structurally-constrained peptides by hydrocarbon stapling of a BCL9 HD2 helix for use as a therapeutic agent. The invention further provides methods and kits for use of the structurally-constrained peptide of the instant invention. The invention is based, at least in part, on the results provided herein demonstrating that hydrocarbon stapled helical peptides display excellent proteolytic, acid, and thermal stability, restore the native helical structure of the peptide, possess superior pharmacokinetic properties compared to the corresponding unmodified peptides, and are highly effective in binding to β-catenin in vitro, in cellulo, and in vivo, disrupting the BCL-9/β-catenin interaction, and thereby interfering with deregulated Wnt/β-catenin signaling for therapeutic benefit in a variety of human diseases including human cancer. |
| FILED | Monday, April 16, 2012 |
| APPL NO | 14/111299 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/82 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703788 | Mohammadi et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
| ABSTRACT | The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF21 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895770 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 38/1825 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class C07K 14/501 (20130101) C07K 14/503 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/50 (20130101) G01N 2500/02 (20130101) G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703791 | Silva Manzano et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Daniel Adriano Silva Manzano (Seattle, Washington); Shawn Yu (Seattle, Washington); Umut Ulge (Seattle, Washington); David Baker (Seattle, Washington); Kenan Christopher Garcia (Seattle, Washington); Jamie Spangler (Seattle, Washington); Carl Walkey (Seattle, Washington) |
| ABSTRACT | De novo designed polypeptides that bind to IL-2 receptor βγc heterodimer (IL-2Rβγc), IL-4 receptor αγc heterodimer (IL-4Rαγc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572038 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 14/5437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703792 | Weiss |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Michael A. Weiss (Indianapolis, Indiana) |
| ABSTRACT | A two-chain insulin analogue contains Aspartic Acid at position B10 and penta-fluoro-Phenylalanine at position B24, optionally Histidine or Glutamic Acid at position A8, optionally additional substitutions or modifications at positions A13 and/or A14 and/or B28 and/or B29. The analogue may be an analogue of a mammalian insulin, such as human insulin, may optionally include (i) N-terminal deletion of one, two or three residues from the B chain, (ii) a mono-peptide or dipeptide C-terminal extension of the B-chain containing at least one acidic residue, and (iii) other modifications known in the art to enhance the stability of insulin. Formulations of the above analogues at successive strengths U-100 to U-1000 in soluble solutions at at least pH value in the range 7.0-8.0 in the absence or presence of zinc ions at a molar ratio of 0.00-0.10 zinc ions per insulin analogue monomer. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/521969 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703805 | Rincon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Julio Rincon (Sunland Park, New Mexico); Thomas Boland (El Paso, Texas) |
| ABSTRACT | Methods and devices for molecular imprinting include a molecular imprinting synthesis and matching a physiological pH of a template utilized in the molecular imprinting synthesis to achieve molecular imprinting. Molecular imprinting can be achieved by matching the physiological pH of the template used in a molecular imprinting synthesis. Furthermore, electrostatic charges can be complementary matched to the template, by obtaining crystallographic data of a protein template. Particularly, positively and negatively charged amino acids can be counted and matched by an oppositely charged monomer. For hydrophobic amino acids, isoleucin, leucin, and valine amino acids are counted. Since not all hydrophobic amino acids are exposed, the hydrophobic amino acid and hydrophobic monomer ratio can be determined experimentally by varying ratios from 1:1 to 1:10. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/366517 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/3057 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/18 (20130101) G01N 2600/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703807 | Weisbart et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. Weisbart (Sepulveda, California); Robert N. Nishimura (Sepulveda, California); James E. Hansen (Guilford, Connecticut) |
| ABSTRACT | The invention provides for a fusion protein comprising a 3E10 Fv joined to a Hsp-70, Hsp-27, Hsp-90 or GRP-78 or portion thereof, and optionally, the 3E10 Fv comprising an amino acid sequence AGIH at its amino terminus. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650752 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703811 | Keane et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Robert W. Keane (Miami, Florida); W. Dalton Dietrich (Miami, Florida); Juan Pablo De Rivero Vaccari (Miami, Florida); Helen M. Bramlett (Miami, Florida); Roberta Brambilla (Miami, Florida) |
| ABSTRACT | The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s). Also described herein are compositions and methods of use thereof for treating multiple sclerosis. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026482 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/55522 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 25/00 (20180101) A61P 25/14 (20180101) A61P 25/28 (20180101) A61P 29/00 (20180101) A61P 37/06 (20180101) Peptides C07K 16/18 (20130101) C07K 16/24 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703816 | Orentas et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Washington, District of Columbia); Ira H. Pastan (Potomac, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Crystal L. Mackall (Stanford, California) |
| ABSTRACT | The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain comprising SEQ ID NOs: 1-6, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/107271 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 15/62 (20130101) C12N 15/63 (20130101) C12N 15/64 (20130101) C12N 15/70 (20130101) C12N 15/85 (20130101) C12N 15/625 (20130101) C12N 2501/505 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703820 | Kapur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tufts Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Tufts Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Navin K. Kapur (Hanover, Massachusetts); Richard H. Karas (Franklin, Massachusetts) |
| ABSTRACT | Endoglin has been identified to play a functional role as a regulator of TGFβ1 signaling, particular in TGFβ1-mediated calcineurin expression. The present invention features methods of reducing cardiac damage, particularly in a subject undergoing chemotherapy or radiation therapy by administering a composition that inhibits endoglin activity. The present invention also features methods of treating autoimmune diseases, inflammatory diseases, organ transplantation, and conditions association with oxidative stress related to TGFβ1-mediated calcineurin expression and reactive oxygen species (ROS) production by administering a composition that inhibits endoglin activity. The present invention also features methods of treating fibrotic diseases by administering a composition that inhibits endoglin activity. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/255521 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/21 (20130101) A61K 38/21 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2066 (20130101) A61K 38/2066 (20130101) A61K 38/4886 (20130101) A61K 38/4886 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 16/2896 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) Enzymes C12Y 304/2408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703823 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); Ryan Murelli (Belleville, New Jersey); Andrew Zhang (Waltham, Massachusetts) |
| ABSTRACT | The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/045855 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4192 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/55 (20170801) A61K 47/68 (20170801) A61K 47/549 (20170801) A61K 47/646 (20170801) A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 47/6873 (20170801) A61K 47/6891 (20170801) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 16/44 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704026 | Kuo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Calvin Jay Kuo (Palo Alto, California); Akifumi Ootani (Stanford, California) |
| ABSTRACT | Methods are provided for long term culture of mammalian intestinal cells. Cultures are initiated with fragments of mammalian intestinal tissue, which are then maintained embedded in a gel substrate that provides an air-liquid interface. Intestinal epithelium in cultures of the invention can be continuously grown for extended periods of time. Mammalian intestinal cells cultured by the methods of the invention recapitulate features of intestinal growth in vivo. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 14/822687 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0679 (20130101) Original (OR) Class C12N 2501/415 (20130101) C12N 2533/54 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704040 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Abzyme Therapeutics LLC (Pottstown, Pennsylvania) |
| ASSIGNEE(S) | Abzyme Therapeutics LLC (Pottstown, Pennsylvania) |
| INVENTOR(S) | Hiep Tran (West Chester, Pennsylvania); Xiaole Chen (Exton, Pennsylvania); Hung Pham (Phoenixville, Pennsylvania); Christine Mary Prokopowitz (Douglassville, Pennsylvania); Rolf Swoboda (Upper Darby, Pennsylvania); Ian White (West Chester, Pennsylvania) |
| ABSTRACT | The present invention provides a triple-mode antibody display system that simultaneously matures, displays and secretes an antibody to a target of interest. An antibody in vivo-matured and complexed with membrane anchored bait can be expressed on the surface of the host cell, while complexed with a soluble bait the antibody is secreted from the host cell. Methods of using the system for identifying binders that bind specifically to an antigen of interest are also provided. Polypeptides, polynucleotides and host cells useful for making the protein binder display system are also provided along with methods of use thereof. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/986025 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/70503 (20130101) C07K 16/00 (20130101) C07K 2317/14 (20130101) C07K 2317/56 (20130101) C07K 2317/60 (20130101) C07K 2318/00 (20130101) C07K 2319/02 (20130101) C07K 2319/20 (20130101) C07K 2319/035 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) C12N 15/81 (20130101) C12N 15/1037 (20130101) C12N 15/1055 (20130101) Original (OR) Class C12N 2800/60 (20130101) C12N 2800/206 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Enzymes C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704049 | Sliz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Piotr Sliz (Canton, Massachusetts); Yunsun Nam (Dallas, Texas) |
| ABSTRACT | The invention provides compositions and methods for regulating microRNA (miRNA) biogenesis. The invention also relates to compositions and methods for treating or preventing cancer in a subject in need thereof. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/984109 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 31/7115 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/645 (20170801) A61K 48/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/47 (20130101) C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704060 | Gersbach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Charles A. Gersbach (Durham, North Carolina); Isaac B. Hilton (Durham, North Carolina); Pablo Perez-Pinera (Lynn, Massachusetts); Ami M. Kabadi (Durham, North Carolina); Pratiksha I. Thakore (Durham, North Carolina); David G. Ousterout (Atlanta, Georgia); Joshua B. Black (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle. |
| FILED | Thursday, June 05, 2014 |
| APPL NO | 14/895316 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Peptides C07K 14/4708 (20130101) C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2740/16043 (20130101) C12N 2800/40 (20130101) C12N 2840/20 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704062 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Kevin Davis (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/132276 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/35 (20130101) C07K 14/721 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/78 (20130101) C12N 15/63 (20130101) C12N 15/907 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704093 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSTIY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Mario Deng (Venice, California); Galyna Bondar (Los Angeles, California) |
| ABSTRACT | Gene expression is measured in a sample of peripheral blood mononuclear cells (PBMCs) obtained from a subject and used to predict organ function recovery. A Function Recovery Potential (FRP) score is assigned to a sample that reflects the measured expression level of the genes identified herein in a direction associated with recovery from organ failure. Treatment of the subject with optimal medical management (OMM) and/or palliative care (PC) is advised when the FRP score is lower than the reference value, and referring the subject for treatment with therapies including—but not limited to—mechanical circulatory support (MCS) surgery, heart transplant (HTx) surgery, or other intervention for advanced heart failure is advised when the FRP score is greater than the reference value. A method for developing an FRP scoring algorithm that predicts a subject's ability to recover from medical intervention for organ failure is also described. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028369 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704096 | Hamm-Alvarez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sarah Hamm-Alvarez (Los Angeles, California); Kaijin Wu (Los Angeles, California); Maria Charlotta Edman (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Sarah Hamm-Alvarez (Los Angeles, California); Kaijin Wu (Los Angeles, California); Maria Charlotta Edman (Los Angeles, California) |
| ABSTRACT | Provided are methods for aiding in diagnosing autoimmune diseases in a mammal, comprising contacting a sample of tear from the mammal with an antibody that specifically binds to a first polypeptide selected from the group Ctss, Ctsh, Ctsr, Ctsw, Ctsz, Ifng, Il16ra, Il10, Il10ra, Il15, Tnfa, Apo-F, or Lcn-2 or a second polypeptide selected from the group lactoperoxidase, lactoferrin or lysozyme under conditions favoring the formation of an antibody-polypeptide complex, and determining the amount of complex formed, wherein an increased formation of antibody-first-polypeptide complex or a decreased formation of antibody-second-polypeptide complex as compared to a suitable control, indicates a likely positive diagnosis of an autoimmune disease for the mammal, thereby aiding in the diagnosis. Methods of treating the autoimmune diseases are also provided. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 13/382286 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704098 | Hakonarson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hakon Hakonarson (Malvern, Pennsylvania); Patrick Sleiman (Philadelphia, Pennsylvania) |
| ABSTRACT | Compositions and methods for the treatment and diagnosis of eosinophilic esophagitis disclosed. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 15/522470 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704105 | Samuels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Yardena Samuels (Potomac, Maryland); Victor Velculescu (Dayton, Maryland); Kenneth Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the PI3K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the PI3K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/836366 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704108 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); D. Williams Parsons (Bellaire, Texas); Xiaosong Zhang (San Francisco, California); Jimmy Cheng-Ho Lin (Baltimore, Maryland); Rebecca J. Leary (Cambridge, Massachusetts); Philipp Angenendt (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Victor Velculescu (Dayton, Maryland); Giovanni Parmigiani (Baltimore, Maryland); Rachel Karchin (Towson, Maryland); Sian Jones (Baltimore, Maryland); Hai Yan (Durham, Maryland); Darell Bigner (Mebane, North Carolina); Chien-Tsun Kuan (Cary, North Carolina); Gregory J. Riggins (White Hall, Maryland) |
| ABSTRACT | We found mutations of the R132 residue of isocitrate dehydrogenase 1 (IDH1) in the majority of grade II and III astrocytomas and oligodendrogliomas as well as in gliblastomas that develop from these lower grade lesions. Those tumors without mutations in IDH1 often had mutations at the analogous R172 residue of the closely related IDH2 gene. These findings have important implications for the pathogenesis and diagnosis of malignant gliomas. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/132928 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704992 | Hayworth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Kenneth Jeffrey Hayworth (Ashburn, Virginia); Richard Schalek (Wakefield, Massachusetts); Juan Carlos Tapia (Bronx, New York); Narayanan Kasthuri (Cambridge, Massachusetts); Jeff W. Lichtman (Cambridge, Massachusetts) |
| ABSTRACT | Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/395931 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 16/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) Original (OR) Class G01N 35/00009 (20130101) G01N 2001/061 (20130101) G01N 2001/065 (20130101) G01N 2001/066 (20130101) G01N 2001/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705007 | Rowlen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Essen Instruments, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Essen Instruments, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Kathy L. Rowlen (Longmont, Colorado); Matthew Ferris (Louisville, Colorado) |
| ABSTRACT | A flow cytometry system and method for quantification of fluorescently labeled virus particles smaller than 1 micron in size measures and controls sample fluid flow rate to an investigatory flow cell at a rate below 5000 nanoliters per minute and calculates in real time particle concentration in the sample fluid using measured flow rated data flow rate data and with correction for sample fluid flow rate fluctuations. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/040168 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) Original (OR) Class G01N 15/1404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705074 | Noble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Paul W. Noble (Beverly Hills, California); Dianhua Jiang (Encino, California); Carol Jiurong Liang (Encino, California) |
| ABSTRACT | The described invention provides a method for identifying a therapeutic compound effective to reduce invasiveness of fibroblasts characterized by a highly invasive phenotype obtained from a subject with idiopathic pulmonary fibrosis. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/761404 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) Original (OR) Class G01N 2500/02 (20130101) G01N 2800/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705168 | Griswold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Mark A. Griswold (Shaker Heights, Ohio); Mingrui Yang (Cleveland, Ohio); Debra McGivney (Rocky River, Ohio) |
| ABSTRACT | A system and method is provided for generating a map of a tissue property in a subject using magnetic resonance fingerprinting (MRF) and a compressed MRF dictionary, where the compressed MRF dictionary has a significantly reduced memory requirement relative to a standard MRF dictionary. The method includes performing a randomized singular value decomposition (rSVD) on a MRF dictionary to produce the compressed MRF dictionary. MRF data is then acquired and compared to the MRF dictionary to identify the tissue property from the region of interest in the subject. A tissue property map is then generated based on the tissue in the region of interest of the subject. |
| FILED | Wednesday, January 17, 2018 |
| APPL NO | 15/873781 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/54 (20130101) Original (OR) Class G01R 33/5608 (20130101) Electric Digital Data Processing G06F 16/56 (20190101) G06F 16/5838 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706548 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kyong Tae Bae (Pittsburgh, Pennsylvania); Youngwoo Kim (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of segmenting an MR organ volume includes performing regional mapping on the MR organ volume using a spatial prior probability map of a location of the organ to create a regionally mapped MR organ volume, and performing boundary refinement on the regionally mapped MR organ volume using a level set framework that employs the spatial prior probability map and a propagated shape constraint to generate a segmented MR organ volume. |
| FILED | Wednesday, September 14, 2016 |
| APPL NO | 15/758358 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6207 (20130101) G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/12 (20170101) G06T 7/73 (20170101) G06T 7/143 (20170101) G06T 2207/10088 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20116 (20130101) G06T 2207/20128 (20130101) G06T 2207/20161 (20130101) G06T 2207/30064 (20130101) G06T 2207/30084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706592 | Sharif et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Behzad Sharif (Los Angeles, California); Debiao Li (South Pasadena, California); Daniel S. Berman (Los Angeles, California); C. Noel Bairey Merz (Pacific Palisades, California) |
| ABSTRACT | In some embodiments, the present application discloses systems and methods for cardiac MRI that allow for continuous un-interrupted acquisition without any ECG/cardiac gating or synchronization that achieves the required image contrast for imaging perfusion defects. The invention also teaches an accelerated image reconstruction technique that is tailored to the data acquisition scheme and minimizes or eliminates dark-rim image artifacts. The invention further enables concurrent imaging of perfusion and myocardial wall motion (cardiac function), which can eliminate the need for separate assessment of cardiac function (hence shortening exam time), and/or provide complementary diagnostic information in CAD patients. |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 14/590935 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/7275 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5601 (20130101) G01R 33/56366 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 40/60 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707011 | Sullivan |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles R. Sullivan (West Lebanon, New Hampshire) |
| ABSTRACT | A multilayer conductor includes at least one separation dielectric layer and a plurality of conductor layers stacked in an alternating manner. Each of the plurality of conductor layers includes a first conductor sublayer and a second conductor sublayer separated from the first conductor sublayer by a sublayer dielectric layer. The second conductor sublayer at least partially overlaps with the first conductor sublayer in each of the plurality of conductor layers. The multilayer conductor is included, for example, in a device including a magnetic core adjacent to at least part of the multilayer conductor. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/166501 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 17/0013 (20130101) H01F 27/16 (20130101) H01F 27/24 (20130101) H01F 27/34 (20130101) Original (OR) Class H01F 27/2804 (20130101) H01F 2017/0026 (20130101) H01F 2027/2809 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/16 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707649 | Yun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Seok Hyun Yun (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 16/306278 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2003/2826 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 2015/1006 (20130101) G01N 2021/6439 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/091 (20130101) H01S 3/169 (20130101) H01S 3/213 (20130101) H01S 3/0604 (20130101) H01S 5/36 (20130101) H01S 5/40 (20130101) H01S 5/041 (20130101) H01S 5/1025 (20130101) H01S 5/1067 (20130101) Original (OR) Class H01S 5/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10702165 | Buller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort, Detrick, Maryland) |
| INVENTOR(S) | Mark J. Buller (Douglas, Massachusetts) |
| ABSTRACT | The invention in at least one embodiment includes a method for determining the core body temperature of a person by setting an initial core body temperature with a processor; receiving a heart rate of the person with the processor; calculating a predicted core body temperature with the processor using an extended Kalman filter based on the heart rate and the initial core body temperature; and providing the predicted core body temperature. In another embodiment, a system for performing the method. |
| FILED | Saturday, March 04, 2017 |
| APPL NO | 15/449943 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) Original (OR) Class A61B 5/024 (20130101) A61B 5/725 (20130101) A61B 5/02438 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702347 | Farritor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | The Regents of the University of California (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Thomas Frederick (Lincoln, Nebraska); Lou Cubrich (Lincoln, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations and at least three degrees of freedom. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691087 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/37 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0024 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702439 | Cavallaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Paul V Cavallaro (Raynham, Massachusetts); Andrew W Hulton (Mansfield, Massachusetts); Gregory J Gudejko (Framingham, Massachusetts); Dustin T Green (Fredericksburg, Virginia); Fred W. A. H. Geurts (Methuen, Massachusetts); Michael G. Hainsworth (Nashua, New Hampshire); Thomas W Kloehn (Centreville, Virginia); Lucienne R Simone (Woodbridge, Virginia) |
| ABSTRACT | A soft transfer case for contaminated material is provided. The transfer case includes a film-laminated, woven textile exterior layer as a pouch. The cylinder is capable of being clamped at each end of the cylinder. An open end elastomeric bladder for containing the contaminated material is contained by the exterior layer. The bladder includes a seam to seal the open end with the material contained therein. Upon pressurization of the bladder, the exterior layer expands and a restraining force is generated between the textile layer and the clamps. A variant of the soft transfer case provides soft end terminations formed by fold-over regions at fold lines in the exterior layer. The exterior layer is fitted with matching locking straps affixed along a longitudinal exterior. The locking straps mechanically lock together. Lifting handles are also affixed to the exterior strength layer to ease transport of the transfer case. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381208 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 17/001 (20170501) A61G 17/06 (20130101) Original (OR) Class A61G 17/007 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702441 | Julin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ekso Bionics, Inc. (Richmond, California) |
| ASSIGNEE(S) | Ekso Bionics, Inc. (Richmond, California) |
| INVENTOR(S) | Aaron Julin (Oakland, California); Mike Hughes (Oakland, California) |
| ABSTRACT | An exoskeleton includes first and second supports coupled to an exoskeleton wearer, a joint connecting the first support to the second support and an actuator. The actuator includes a ball screw, a ball nut assembly coupled to the ball screw and first and second tensile members. The ball nut assembly has first and second cord reactors. The first tensile member is routed through the first cord reactor, and the second tensile member is routed through the second cord reactor. Movement of the ball nut assembly along the ball screw in a first direction causes the second support to move relative to the first support in a first rotational direction about the joint. Movement of the ball nut assembly along the ball screw in a second direction causes the second support to move relative to the first support in a second rotational direction about the joint. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499078 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2201/1207 (20130101) A61H 2201/5061 (20130101) A61H 2201/5071 (20130101) A61H 2205/10 (20130101) A61H 2205/088 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/104 (20130101) Gearing F16H 19/0622 (20130101) F16H 25/2204 (20130101) F16H 2025/2062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702474 | Sailor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael J. Sailor (La Jolla, California); Byungji Kim (Cambridge, Massachusetts); Jinyoung Kang (La Jolla, California) |
| ABSTRACT | The disclosure describes a fusogenic liposome-coated porous silicon nanoparticles for high loading efficiency of anionic payloads (small molecules, dyes, nucleic acids), and for non-endocytic delivery of hydrophilic and lipophilic payloads by membrane fusion. The liposome coating can be further modified with targeting peptides or antibodies via covalent binding chemistry between the ligands and functionalized poly(ethylene glycol). The surface moieties can be transferred to the cellular membrane surface by fusogenic uptake. The composition of the disclosure can be applied in the treatment of diseases by delivering entrapped/encapsulated payloads. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/741649 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 31/713 (20130101) A61K 47/64 (20170801) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702481 | Myerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Allan S. Myerson (Boston, Massachusetts); Mohammad A. Azad (Quincy, Massachusetts); Gregory J. Hammersmith (Windsor, Connecticut); David Brancazio (Cambridge, Massachusetts); Juan Guillermo Osorio Caicedo (Elizabeth, New Jersey) |
| ABSTRACT | Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs). |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/898010 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 3/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/2009 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2095 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/5513 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/1061 (20130101) B01F 13/1063 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/34 (20130101) Presses in General B30B 11/08 (20130101) B30B 11/027 (20130101) B30B 15/302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702510 | Burback et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio); Jessica Catherine Bright (Dublin, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Brian L. Burback (Hilliard, Ohio); Jessica Catherine Bright (Dublin, Ohio); Jerry D. Johnson (Dublin, Ohio) |
| ABSTRACT | Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced muscle contraction/neuromuscular blockade. Kits and articles of manufacture comprising a container having a label and a composition are also disclosed. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 15/885987 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/14 (20130101) A61J 2205/30 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/15 (20130101) A61K 31/15 (20130101) A61K 31/444 (20130101) Original (OR) Class A61K 31/4425 (20130101) A61K 31/4425 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/02 (20180101) A61P 41/00 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702521 | Widdowson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GlaxoSmithKline Intellectual Property Development Limited (Brentford, Middlesex, United Kingdom) |
| ASSIGNEE(S) | GlaxoSmithKline Intellectual Property Development Limited (, United Kingdom) |
| INVENTOR(S) | Katherine Louisa Widdowson (San Diego, California) |
| ABSTRACT | The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions. |
| FILED | Thursday, August 20, 2015 |
| APPL NO | 15/505715 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) A61K 31/542 (20130101) A61K 31/554 (20130101) A61K 31/4375 (20130101) A61K 31/4545 (20130101) A61K 31/4725 (20130101) A61K 31/4985 (20130101) Original (OR) Class A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 31/5415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702571 | Bahr |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Pembroke (Pembroke, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Pembroke (Pembroke, North Carolina) |
| INVENTOR(S) | Ben A. Bahr (Lake Waccamaw, North Carolina) |
| ABSTRACT | The present invention provides methods for treating a subject afflicted with a protein accumulation disease or TBI, comprising administering to the subject at least one compound that increases the level of active cathepsin B in cells of the subject, or a pharmaceutically acceptable salt or ester thereof, in an amount that is effective to treat the subject. The present invention also provides compositions for treating a subject afflicted with a protein accumulation disease or TBI. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/780971 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 5/06078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702803 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Joohoon Kang (Evanston, Illinois) |
| ABSTRACT | Separation of rhenium disulfide nanomaterials and related fluid density gradient media. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/800666 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 21/26 (20130101) Original (OR) Class B01D 21/283 (20130101) Flotation; Differential Sedimentation B03D 3/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 47/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/02 (20130101) C01P 2004/04 (20130101) C01P 2004/20 (20130101) C01P 2004/30 (20130101) C01P 2004/61 (20130101) C01P 2006/10 (20130101) C01P 2006/40 (20130101) C01P 2006/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703466 | Darrow, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | David A. Darrow, Jr. (Stratford, Connecticut); Ron William Waldo (North Richland Hills, Texas); Christopher L. Winslow (Trumbull, Connecticut) |
| ABSTRACT | A propulsor hub is provided and includes a casing including an inner annular part and blade-connection parts extending outwardly from the inner annular part, a liner having inner and outer opposed radial ends, the liner being disposed about a corresponding one of the blade-connection parts with the inner radial end thereof at a distance from the inner annular part and a weighted element securely disposed about the corresponding one of the blade-connection parts to abut the outer radial end of the liner. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/568658 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/06 (20130101) B64C 27/008 (20130101) Original (OR) Class B64C 27/10 (20130101) B64C 27/32 (20130101) B64C 27/48 (20130101) B64C 27/82 (20130101) B64C 2027/8236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703468 | Kopanski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Krzysztof Kopanski (Trumbull, Connecticut); Justin Thomas (New Haven, Connecticut) |
| ABSTRACT | A blade includes a blade body having a surface and a hole extending through the surface of the blade body. The hole defines a hole axis and a plane perpendicular to the hole axis. The hole has an elongated hole perimeter within the plane. The hole perimeter includes a plurality of non-linear perimeter sections to minimize stress concentration around the elongated hole perimeter while maximizing the usable opening area. A rotor system includes a rotor hub and a blade as recited above. The blade extends radially outward from the rotor hub. The blade defines a root end proximate to the rotor hub, a tip end opposite the root end. |
| FILED | Tuesday, September 13, 2016 |
| APPL NO | 15/756777 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703472 | Scott |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Mark W. Scott (Bethany, Connecticut) |
| ABSTRACT | A rotary winged aircraft includes an airframe and a drive system located at the airframe. A main rotor system is positioned at the airframe and is operably connected to the drive system to provide lift for the rotary winged aircraft. An auxiliary propulsor is located at the airframe and includes a plurality of propeller blades rotatable about a propulsor axis. Collective and cyclic pitch input applied to the auxiliary propeller blades increases yaw performance of the aircraft. A method of operating a rotary wing aircraft includes powering an auxiliary propulsor secured to an airframe of the aircraft and including a plurality of propeller blades rotatable about a propulsor axis. Individual propeller blades are cyclically rotated about their respective propeller blade axes to cyclically change a propeller blade pitch. Rotation of the aircraft about a yaw axis is induced via the collective and cyclic pitch change of the propeller blades. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 15/534393 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/82 (20130101) Original (OR) Class B64C 2027/8236 (20130101) B64C 2027/8272 (20130101) B64C 2027/8281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703501 | Pruzan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analytical Mechanics Associates, Inc. (Hampton, Virginia) |
| ASSIGNEE(S) | ANALYTICAL MECHANICS ASSOCIATES, INC. (Hampton, Virginia) |
| INVENTOR(S) | Daniel Allan Pruzan (Redwood City, California); Daniel Joseph Lesieutre (San Jose, California) |
| ABSTRACT | Systems, apparatus, and methods may control movement of an object through a fluid. The systems, apparatus, and methods may utilize a rotatable control unit including a pair of fins to generate a control force at least partially perpendicular to a direction of travel of the object through the fluid. One fin may be configured to generate a different amount of rolling moment than the other fin to provide rotational acceleration and energy production. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/461685 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/02 (20130101) Original (OR) Class B64D 39/04 (20130101) B64D 39/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703505 | Schimke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOODRICH CORPORATION (Charlotte, North Carolina) |
| ASSIGNEE(S) | GOODRICH CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Adam M. Schimke (Gilbert, Arizona); Gerald Brandon Biehle (Phoenix, Arizona) |
| ABSTRACT | A seal assembly includes a housing, a shaft, and a gland. The housing defines an opening and an annular retention channel, according to various embodiments. The shaft extends through the opening, and the shaft comprises a longitudinal axis, according to various embodiments. The gland may be disposed circumferentially around the shaft and may be movably retained within the annular retention channel. The gland is movable relative to the housing in a direction substantially perpendicular to the longitudinal axis, according to various embodiments. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/387972 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/02 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) Pistons; Cylinders; Sealings F16J 15/453 (20130101) F16J 15/3268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703637 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois) |
| ABSTRACT | A boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension and a method for preparation thereof. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 15/430885 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703687 | Stepanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Victor Stepanov (Highland Park, New Jersey); Rajen Patel (Parsippany, New Jersey); Chris Pizzo (Ridgewood, New Jersey); Alexander Paraskos (Sparta, New Jersey); Ruslan Mudryy (Union, New Jersey); Hongwei Qiu (Harrison, New Jersey) |
| ABSTRACT | Stabilized, amorphous high energetic compositions having crystallization inhibiting polymers dispersed throughout the solid composition. The compositions disclosed herein are an improvement over crystalline high energetic compositions in that such disclosed compositions are stable and possess physical properties desirable in propellant and high explosive applications. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 15/817746 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0016 (20130101) C06B 21/0025 (20130101) C06B 21/0091 (20130101) C06B 23/006 (20130101) C06B 25/34 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/18 (20130101) Compositions of Macromolecular Compounds C08L 1/12 (20130101) C08L 1/14 (20130101) C08L 31/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704062 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Kevin Davis (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/132276 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/35 (20130101) C07K 14/721 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/78 (20130101) C12N 15/63 (20130101) C12N 15/907 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704076 | Hassett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio); Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio); Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Daniel J. Hassett (Cincinnati, Ohio); Thomas J. Lamkin (Cincinnati, Ohio); Warunya Panmanee (Cincinnati, Ohio); Deborah E. Taylor (Cincinnati, Ohio); Chloe J. A. Shea (Cincinnati, Ohio) |
| ABSTRACT | A high through-put screening method for identifying agents effective for inhibiting biofilm formation and/or killing established biofilm are disclosed. The method includes three tiers, and each tier includes three specific biological process assays. The tier levels are a primary screen, a confirmation screen, and a dose-response screen, and the biological process assays include assays for total bacterial growth, bacterial metabolic activity, and biofilm formation. The series of assays may be run once or more than once at each tier. A library of compounds is subject to tier A and only compounds meeting a primary parameter advance to tier B, and only tier B compounds meeting a confirmation parameter advance to tier C, and only tier C compounds meeting a dose-response parameter are identified as putative agents effective for inhibiting and/or eradicating a biofilm, further wherein the assays are conducted for each compound subject to the respective tier. The method is effective and validated for identifying agents which inhibit and/or kill Staphylococcus epidermidis, Pseudomonas aeruginosa, and Acinetobacter baumannii biofilms. Agents identified according to the high through-put screen and validated in follow-up experiments as effective for inhibiting and/or killing bacterial biofilms are also disclosed. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/224006 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/10 (20130101) A01N 37/28 (20130101) A01N 41/06 (20130101) A01N 43/12 (20130101) A01N 43/38 (20130101) A01N 43/42 (20130101) A01N 43/44 (20130101) A01N 43/52 (20130101) A01N 43/54 (20130101) A01N 43/56 (20130101) A01N 43/80 (20130101) A01N 43/82 (20130101) A01N 43/90 (20130101) A01N 47/38 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/175 (20130101) A61K 31/216 (20130101) A61K 31/343 (20130101) A61K 31/404 (20130101) A61K 31/425 (20130101) A61K 31/435 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4155 (20130101) A61K 31/4184 (20130101) A61K 31/4245 (20130101) A61K 31/4545 (20130101) A61K 31/4709 (20130101) Acyclic or Carbocyclic Compounds C07C 69/738 (20130101) C07C 243/28 (20130101) C07C 311/21 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 215/52 (20130101) C07D 215/56 (20130101) C07D 231/20 (20130101) C07D 235/18 (20130101) C07D 271/12 (20130101) C07D 275/03 (20130101) C07D 307/92 (20130101) C07D 401/04 (20130101) C07D 405/04 (20130101) C07D 405/14 (20130101) C07D 413/04 (20130101) C07D 471/04 (20130101) C07D 491/052 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704140 | Bol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ageeth A Bol (Yorktown Heights, New York); Xuesong Li (Yorktown Heights, New York) |
| ABSTRACT | An apparatus and method for graphene film synthesis. The apparatus includes a quasi-enclosed substrate holder which includes one open side, a cap disposed over the one open side of the quasi enclosed substrate holder, and a substrate for graphene film synthesis located inside the quasi enclosed substrate holder. The method includes placing a substrate for graphene film synthesis inside of a quasi-enclosed substrate holder and generating a graphene film on the substrate via chemical vapor deposition, wherein the quasi enclosed substrate holder includes one open side and a cap disposed over the open side of the quasi enclosed substrate holder. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012178 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Original (OR) Class C23C 16/4582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704424 | Burd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Steven W. Burd (Cheshire, Connecticut); Christopher R. Brdar (Rocky Hill, Connecticut); Derk S. Philippona (Tolland, Connecticut) |
| ABSTRACT | A component for a gas turbine engine includes a substrate with a substrate aperture and a coating on the substrate that extends a length of the substrate aperture. A liner assembly for a gas turbine engine includes a hot sheet with a multiple of apertures and a coating on the hot sheet that extends a length of each of the multiple of apertures. A method of forming an aperture to provide film cooling in a component of a gas turbine engine, includes forming a multiple of substrate apertures in a substrate. Each of the multiple of substrate apertures defines a substrate inner periphery. A coating is applied on the substrate after forming the multiple of substrate apertures to define a coating inner periphery at least partially within each of the multiple of substrate apertures. The coating inner periphery is smaller than the substrate inner periphery. |
| FILED | Thursday, September 04, 2014 |
| APPL NO | 15/029525 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/30 (20130101) F01D 25/145 (20130101) F01D 25/305 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) Jet-propulsion Plants F02K 1/822 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/10 (20130101) F05D 2230/31 (20130101) F05D 2230/90 (20130101) F05D 2240/15 (20130101) F05D 2250/38 (20130101) F05D 2260/202 (20130101) F05D 2260/231 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) Y02T 50/6765 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704537 | Ting et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jason Ming Ting (Katy, Texas); Alok Suryavamsee Tayi (Somerville, Massachusetts); Bobak Mosadegh (New York, New York); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other. |
| FILED | Tuesday, May 29, 2018 |
| APPL NO | 15/991008 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/02 (20130101) B29C 66/45 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/0342 (20130101) B29C 66/712 (20130101) B29C 66/1122 (20130101) B29C 66/5346 (20130101) B29C 66/73921 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2021/003 (20130101) B29K 2075/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/26 (20130101) B32B 5/028 (20130101) B32B 7/02 (20130101) B32B 27/08 (20130101) B32B 27/40 (20130101) B32B 37/04 (20130101) B32B 37/18 (20130101) B32B 2307/51 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) Y10T 156/1041 (20150115) Y10T 428/2495 (20150115) Y10T 428/24331 (20150115) Y10T 428/24612 (20150115) Y10T 428/24942 (20150115) Y10T 428/24983 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704538 | Gieseke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Thomas J Gieseke (Warren, Rhode Island) |
| ABSTRACT | An impulse pump is provided with a low power motor to store rotational kinetic energy in a flywheel. The stored kinetic energy is released using a planetary gear transmission that links the flywheel to a pusher shaft. The kinetic energy is released when the planetary gear carrier is decelerated using a caliper brake. The planetary gear carrier deceleration forces rotational acceleration of the pusher shaft and deceleration of the flywheel. Through a cam roller contact point between the pusher shaft and the cam raceway on the plunger; the rotational motion of the pusher shaft is converted to linear and translational motion of the plunger. The translational motion of the plunger allows impulse jet energy to be rapidly released from a nozzle of the pump. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139105 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 9/02 (20130101) F04B 9/06 (20130101) F04B 9/042 (20130101) Original (OR) Class F04B 17/03 (20130101) F04B 19/22 (20130101) F04B 23/028 (20130101) F04B 53/14 (20130101) F04B 53/16 (20130101) Gearing F16H 1/28 (20130101) F16H 57/10 (20130101) F16H 57/082 (20130101) F16H 2057/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704563 | Parker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | David Vickery Parker (Lynn, Massachusetts); Wilhelm Ramon Hernandez (Lynn, Massachusetts); Basuki Srivastava (Lynn, Massachusetts); Paul Trimby (Lynn, Massachusetts) |
| ABSTRACT | A compressor apparatus includes: an upstream portion comprising an axial-flow compressor; a downstream portion comprising a centrifugal-flow compressor; and a row of variable-stagger-angle outlet guide vanes disposed between the upstream and downstream portions. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 15/510841 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Non-positive-displacement Pumps F04D 17/025 (20130101) F04D 19/02 (20130101) F04D 29/403 (20130101) F04D 29/462 (20130101) Original (OR) Class F04D 29/563 (20130101) F04D 29/4213 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704571 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Pete Lynn (Oakland, California); Kevin Albert (San Francisco, California); Giancarlo Nucci (San Francisco, California); Tim Swift (Clovis, California); Maria Telleria (Redwood City, California); Loren Russell (Berkeley, California); Jonathan Pompa (Long Beach, California) |
| ABSTRACT | A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997337 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) Original (OR) Class F15B 15/202 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/06 (20130101) F16K 17/048 (20130101) F16K 31/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704665 | Rizk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RE2, Inc. (, None) |
| ASSIGNEE(S) | RE2, Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Nabil Michael Rizk (Pittsburgh, Pennsylvania); Gregory D. Danyo (Pittsburgh, Pennsylvania); Andrew B. Mor (Pittsburgh, Pennsylvania) |
| ABSTRACT | A fluid rotary joint has a stator with a generally curved stator body and a flex spline with a flexible annular band disposed about and secured to the stator body. The stator also has at least three radially extendable members disposed between the stator body and the annular band to deform the annular band away from the stator body to contact the inner surface of a rotor. The inner circumference of the rotor is greater than the outer circumference of the annular band. A driver selectively expands the extendable members and brings the annular band of the stator into frictional driving engagement with the rotor for rotating the rotor. The extendable members may also be selectively extended to allow the stator and rotor to freely move with respect to one another or to have limited contact with one another to act as a torque limiting device. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/612578 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Gearing F16H 49/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704839 | Hoang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Triem T. Hoang (Clifton, Virginia) |
| ABSTRACT | A two-phase heat transfer system including at least one two-phase evaporator, at least one condenser, a vapor conduit joining a vapor outlet of the two-phase evaporator to an inlet of the condenser, a liquid conduit joining an outlet of the condenser to a liquid inlet of the two-phase evaporator, and a thermally-actuated capillary flow valve. The thermally-actuated capillary flow valve having a valve inlet, a valve outlet, a thermal connection to a heat sink for cold biasing the capillary flow valve, a porous wick extending across the flow passageway of the capillary flow valve, and a heater thermally connected to the capillary flow valve, where actuation of the heater evaporates liquid in the porous wick to allow passage of vapor through the capillary flow valve. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042663 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/043 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704847 | Haugstetter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Christoph Haugstetter (West Hartford, Connecticut) |
| ABSTRACT | A system is provided. The system includes at least two heat exchangers that are alternatively cooled by an outlet medium. The system also includes a cooling circuit that provides a cooling medium to the at least two heat exchangers. The cooling circuit provides the cooling medium to a first heat exchanger of the at least two heat exchangers in accordance with a first mode. The cooling circuit provide the cooling medium to a second heat exchanger of the at least two heat exchangers in accordance with a second mode. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/709795 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 11/04 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/10 (20130101) Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 1/055 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/004 (20130101) F25B 17/12 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 17/00 (20130101) F28F 27/00 (20130101) F28F 27/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704881 | Foltz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee Foltz (Indian Head, Maryland); Dan McCarthy (LaPlata, Maryland) |
| ABSTRACT | A novel dearmer enables EOD technicians to propel dearmer projectiles using conventional electric .50 caliber blank cartridges or conventional non-electric 12 gauge blank cartridges. The dearmer projectiles may render energetic threats safe without requiring an opposing force to offset the recoil. The conventional blank cartridge functions as a rocket motor that supplies gas to a converging/diverging nozzle. Alternatively, liquid is loaded into the dearmer (creating a liquid rocket effect) and the EOD projectile is propelled toward a target from the end of the dearmer opposite the liquid. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/602049 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 33/06 (20130101) Blasting F42D 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705092 | Delehanty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of Americam as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James B. Delehanty (Washington, District of Columbia); Michael H. Stewart (Springfield, Virginia); Okhil Nag (Alexandria, Virginia); Jeffrey R. Deschamps (Laurel, Maryland); Kimihiro Susumu (Alexandria, Virginia); Eunkeu Oh (Alexandria, Virginia); Lauren D. Field (College Park, Maryland); Alexander L. Efros (Annandale, Virginia); Alan L. Huston (Aldie, Virginia); Igor L. Medintz (Springfield, Virginia); Philip E. Dawson (San Diego, California) |
| ABSTRACT | A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 15/882259 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705112 | Dorr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Joshua Dorr (Minneapolis, Minnesota); Chad Fertig (Bloomington, Minnesota); Arthur Savchenko (Kirkland, Washington); Neil Krueger (Saint Paul, Minnesota); Steven Tin (Plymouth, Minnesota) |
| ABSTRACT | An optomechanical device comprising a circuit configured to generate an optical signal using a tuning signal and modulate the optical signal at a frequency corresponding to one quarter of a Full Width at Half Maximum (FWHM) of an optical resonance of the proof mass assembly to generate a partially modulated optical signal. The circuit being further configured to filter the partially modulated optical signal to remove a central carrier from the partially modulated optical signal to generate a filtered optical signal, modulate the filtered optical signal to generate a modulated optical signal driven to the mechanical resonance of the proof mass assembly, and generate the tuning signal using a difference between a DC intensity level of a first optical frequency component in the modulated optical signal and a DC intensity level of a second optical frequency component in the modulated optical signal. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/391074 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/02 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/003 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0014 (20130101) H01S 5/0085 (20130101) Multiplex Communication H04J 14/0202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705163 | Barry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John F. Barry (Cambridge, Massachusetts); Danielle A. Braje (Winchester, Massachusetts); Erik R. Eisenach (Cambridge, Massachusetts); Christopher Michael McNally (Cambridge, Massachusetts); Michael F. O'Keeffe (Medford, Massachusetts); Linh M. Pham (Arlington, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John F. Barry (Cambridge, Massachusetts); Danielle A. Braje (Winchester, Massachusetts); Erik R. Eisenach (Cambridge, Massachusetts); Christopher Michael McNally (Cambridge, Massachusetts); Michael F. O'Keeffe (Medford, Massachusetts); Linh M. Pham (Arlington, Massachusetts) |
| ABSTRACT | Here we present a solid-state spin sensor with enhanced sensitivity. The enhanced sensitivity is achieved by increasing the T2* dephasing time of the color center defects within the solid-state spin sensor. The T2* dephasing time extension is achieved by mitigating dipolar coupling between paramagnetic defects within the solid-state spin sensor. The mitigation of the dipolar coupling is achieved by applying a magic-angle-spinning magnetic field to the color center defects. This field is generated by driving a magnetic field generator (e.g., Helmholtz coils) with phase-shifted sinusoidal waveforms from current source impedance-matched to the magnetic field generator. The waveforms may oscillate (and the field may rotate) at a frequency based on the precession period of the color center defects to reduce color center defect dephasing and further enhance measurement sensitivity. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/204381 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/12 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class G01R 33/307 (20130101) G01R 33/445 (20130101) G01R 33/3607 (20130101) G01R 33/3678 (20130101) G01R 33/34061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705182 | Win et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Moe Z. Win (Framingham, Massachusetts); Stefania Bartoletti (Cambridge, Massachusetts); Wenhan Dai (Cambridge, Massachusetts); Andrea Conti (Bologna, Italy) |
| ABSTRACT | A ranging system includes an input for receiving a wireless signal and a detector for determining an estimate of a time-of-arrival of the wireless signal at the ranging system. The detector includes a first module for processing the wireless signal according to a non-linear, monotonic transformation to generate a modified signal, a second module for compressing the modified signal according to a linear transformation, resulting in a compressed signal including a number of elements, each element corresponding to a different time segment of the modified signal, and a third module for applying a decision function for determining an output including a first element of the number of elements, corresponding to the time-of-arrival of the wireless signal at the ranging system, applying the decision function, including comparing the elements of the compressed signal to corresponding thresholds of a number of thresholds associated with the number of elements. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627822 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/021 (20130101) Original (OR) Class G01S 7/2923 (20130101) G01S 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705187 | Hebert |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James L. Hebert (Waldorf, Maryland) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | James L. Hebert (Waldorf, Maryland) |
| ABSTRACT | An aerial drone or unmanned aerial vehicle (UAV) is provided for radar calibration testing. The drone includes an airframe including a fuselage with nose and tail, wings and elevators. The drone includes at least one antenna attached to the airframe, as well as a signal adapter coupled to the antenna to receive impinging radar signals and transmit an electromagnetic (EM) field that effectively cancels or combines with the scattered field of the drone, depending upon the adapter's mode of operation. In the first mode of operation, the adapter transmits an EM field that has an opposite phase to the drone's scattered field thereby reducing the radar cross-section of the drone. In the second mode, the adapter transmits an EM field that is in-phase with the scattered field thereby increasing the radar cross-section of the drone. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 15/598352 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Targets; Target Ranges; Bullet Catchers F41J 9/08 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/411 (20130101) Original (OR) Class G01S 7/414 (20130101) Transmission H04B 1/02 (20130101) H04B 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705273 | Chiao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Shu-Chung Chiao (Richardson, Texas) |
| ABSTRACT | Multispectral optical interference coatings and methods. In one example, an optical element includes a substrate having a first surface and a second surface disposed opposite the first surface, a first multi-layer dielectric film disposed on the first surface of the substrate and constructed and arranged to transmit light in a first band of wavelengths, a second multi-layer dielectric film disposed on the second surface of the substrate and constructed and arranged to transmit light in a second band of wavelengths, the first and the second bands of wavelengths at least partially overlapping, and a bilayer diamond-like carbon (DLC) coating disposed on the first multi-layer dielectric film, the bilayer DLC coating including a first layer and a second layer, the first layer having a modulus of elasticity of a first value, and the second layer disposed on the first layer and having a modulus of elasticity of a second value that is greater than the first value. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/935675 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/0227 (20130101) C23C 16/272 (20130101) C23C 16/505 (20130101) C23C 16/45523 (20130101) C23C 28/046 (20130101) Optical Elements, Systems, or Apparatus G02B 1/02 (20130101) G02B 5/26 (20130101) G02B 5/281 (20130101) Original (OR) Class G02B 5/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705298 | Harrigan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Matthew P. Harrigan (Rochester, New York); Nathaniel Dew (Stratford, Connecticut); Eric C. Schenck (Rochester, New York) |
| ABSTRACT | A core-stiffed composite structure includes a plurality of bonded layers forming the core-stiffened composite structure, a fiber optic conductor embedded between two of the plurality of bonded layers, the fiber optic conductor including a terminal end, and a protective box embedded in the core-stiffened composite structure and bonded to one or more of the plurality of bonded layers, wherein the terminal end of the fiber optic conductor projects into the protective box. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/395430 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/26 (20130101) G02B 6/3696 (20130101) Original (OR) Class G02B 6/3897 (20130101) G02B 6/4471 (20130101) G02B 2006/12138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706129 | Konoske et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paula Konoske (San Diego, California); Michael Galarneau (San Diego, California); Ray Mitchell (Huntsville, Alabama); Johnny Brock (Brownsboro, Alabama) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Paula Konoske (San Diego, California); Michael Galarneau (San Diego, California); Ray Mitchell (Huntsville, Alabama); Johnny Brock (Brownsboro, Alabama) |
| ABSTRACT | This invention are computer implementable programs and method designed as medical planning tool that (1) models the patient flow from the point of injury through more definitive care, and (2) supports operations research and systems analysis studies, operational risk assessment, and field medical services planning. The computer program of this invention comprises six individual modules, including the casualty generation module, which uses an exponential distribution to stochastically generate wounded in action, disease, and nonbattle injuries; a care providing module uses generic task sequences, simulated treatment times, and personnel, consumable supply, and equipment requirements to model patient treatment and queuing within a functional area; a network/transportation module simulates the evacuation (including queuing) and routing of patients through the network of care via transportation assets; a reporting module produces an database detailing various metrics, such as patient disposition, time-in-system data, and consumable, equipment, personnel, and transportation utilization rates, which can be filtered according to the user's needs. |
| FILED | Thursday, February 27, 2014 |
| APPL NO | 14/192521 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 19/3481 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706564 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mohit Gupta (Madison, Wisconsin); Sizhuo Ma (Madison, Wisconsin); Brandon Smith (Freemont, California) |
| ABSTRACT | In accordance with some embodiments, systems, methods and media for determining object motion in three dimensions using light field image data are provided. In some embodiments, a system for three dimensional motion estimation is provided, comprising: an image sensor; optics that create many images of a scene; and a hardware processor configured to: cause the image sensor to capture a first plurality of images; generate a first light field; cause the image sensor to capture a second plurality of images at a second time; generate a second light field; calculate light field gradients using the first light field and second light field; and calculate, for each point in the scene, three dimensional motion using the light field gradients by applying a constraint to the motion in the scene. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/951131 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/269 (20170101) G06T 7/285 (20170101) Original (OR) Class Pictorial Communication, e.g Television H04N 13/243 (20180501) H04N 2013/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707547 | Morton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Matthew A. Morton (Reading, Massachusetts); Gerhard Sollner (Winchester, Massachusetts); Jason C. Soric (Bedford, Massachusetts) |
| ABSTRACT | A frequency selective limiter (FSL) is provided having a transmission line structure with a tapered width. The FSL includes a magnetic material having first and second opposing surfaces. A first conductor is disposed on the first surface of the magnetic material, where a width of the first conductor decreases from a first end of the FSL to a second end of the FSL along a length of the FSL. Two second conductors are disposed on the second surface of the magnetic material, where a width of a gap between the two second conductors decreases from the first end of the FSL to the second end of the FSL along a length of the FSL. The first conductor and two second conductors form a biplanar waveguide transmission line. |
| FILED | Tuesday, June 26, 2018 |
| APPL NO | 16/018768 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/23 (20130101) Original (OR) Class H01P 1/215 (20130101) H01P 1/218 (20130101) H01P 1/227 (20130101) H01P 3/08 (20130101) H01P 11/003 (20130101) Control of Amplification H03G 11/00 (20130101) H03G 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707975 | Pratt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Thomas G. Pratt (Niles, Michigan); Robert Daniel Kossler (South Bend, Indiana); Jeffrey G. Mueller (South Bend, Indiana); Joseph Lawrence Loof (Notre Dame, Indiana) |
| ABSTRACT | A signal source association method and receiver. A receiver can be used to detect a plurality of signals transmitted from a plurality of transmission sources. The receiver can determine amplitude and phase information for a plurality of frequency components of each of the plurality of signals. The receiver can also determine a set of comparison values by comparing the respective amplitude and phase information from one or more pairs of the plurality of signals. Finally, the receiver can associate one of the signals with one of the plurality of transmission sources using the set of comparison values. The comparison values can comprise Stokes parameters and the one or more pairs of the plurality of signals can comprise a pair of orthogonally polarized signals or a pair of signals detected from spatially-separated antennas. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/134370 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0851 (20130101) H04B 17/12 (20150115) H04B 17/27 (20150115) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707985 | Swarup |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AshRem Technologies, Inc. (Burbank, California) |
| ASSIGNEE(S) | ASHREM TECHNOLOGIES, INC. (Burbank, California) |
| INVENTOR(S) | Ashitosh Swarup (Burbank, California) |
| ABSTRACT | Example communication systems and methods are described. In one implementation, a method receives a first chaotic sequence of a first temporal length, and a second chaotic sequence of a second temporal length. The method also receives a data symbol for communication to a destination. Based on the data symbol, the second chaotic sequence is temporally shifted and combined with the first chaotic sequence to generate a composite chaotic sequence. The first chaotic sequence functions as a reference chaotic sequence while the second chaotic sequence functions as a data-carrying auxiliary chaotic sequence. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283192 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Multiplex Communication H04J 13/10 (20130101) H04J 13/0018 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0016 (20130101) H04L 27/001 (20130101) H04L 27/18 (20130101) H04L 27/2278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10708295 | Hagelstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| INVENTOR(S) | Ryan L. Hagelstrom (Chaska, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Nathan E. Bahr (Eden Prairie, Minnesota) |
| ABSTRACT | A method of cyber-attack protection is provided. The method includes receiving a unicast packet at a first router and determining whether a destination for the unicast packet is behind a cooperating router. If the destination for the unicast packet is behind a cooperating router, the unicast packet is tunneled from the first router to a tunnel multicast address to which the cooperating router subscribes. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/611074 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/18 (20130101) H04L 12/4633 (20130101) H04L 45/64 (20130101) H04L 63/029 (20130101) H04L 63/0236 (20130101) H04L 63/0428 (20130101) H04L 63/1433 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10708548 | Rasheed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AVIGILON FORTRESS CORPORATION (Vancouver, Canada) |
| ASSIGNEE(S) | AVIGILON FORTRESS CORPORATION (Vancouver, Canada) |
| INVENTOR(S) | Zeeshan Rasheed (Herndon, Virginia); Dana Eubanks (Herndon, Virginia); Weihong Yin (Great Falls, Virginia); Zhong Zhang (Great Falls, Virginia); Kyle Glowacki (Reston, Virginia); Allison Beach (Leesburg, Virginia) |
| ABSTRACT | Systems, methods and computer-readable media for creating and using video analysis rules that are based on map data are disclosed. A sensor(s), such as a video camera, can track and monitor a geographic location, such as a road, pipeline, or other location or installation. A video analytics engine can receive video streams from the sensor, and identify a location of the imaged view in a geo-registered map space, such as a latitude-longitude defined map space. A user can operate a graphical user interface to draw, enter, select, and/or otherwise input on a map a set of rules for detection of events in the monitored scene, such as tripwires and areas of interest. When tripwires, areas of interest, and/or other features are approached or crossed, the engine can perform responsive actions, such as generating an alert and sending it to a user. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139446 |
| ART UNIT | 2423 — Cable and Television |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) G06K 9/3241 (20130101) G06K 9/6255 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) G06T 2207/30232 (20130101) G06T 2219/2004 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19671 (20130101) Pictorial Communication, e.g Television H04N 7/181 (20130101) Original (OR) Class H04N 7/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D889581 | Facteau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert J. Facteau (Troy, New York); Joshua W. Ward (Fort Polk, Louisiana); George E. Hathaway, IV (Watervliet, New York); Karolanne L. Madulka (Ballston Spa, New York); Wayland P. Barber (Mechanicville, New York); Brian J. Van De Wal (Schodack, New York) |
| ABSTRACT | |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 29/654742 |
| ART UNIT | 2922 — Design |
| CURRENT CPC | Arms, pyrotechnics, hunting and fishing equipment D22/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D889583 | Grego et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Thomas C. Grego (Chester, New Jersey); Adam Foltz (Long Valley, New Jersey) |
| ABSTRACT | |
| FILED | Friday, December 07, 2018 |
| APPL NO | 29/672642 |
| ART UNIT | 2922 — Design |
| CURRENT CPC | Arms, pyrotechnics, hunting and fishing equipment D22/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10702347 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | The Regents of the University of California (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Thomas Frederick (Lincoln, Nebraska); Lou Cubrich (Lincoln, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations and at least three degrees of freedom. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691087 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/37 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0024 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702402 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tyagi Ramakrishnan (Tampa, Florida); Kyle B. Reed (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Tyagi Ramakrishnan (Tampa, Florida); Kyle B. Reed (Tampa, Florida) |
| ABSTRACT | A passive knee locking mechanism using the position of the shank and the weight of the user to lock. The mechanism has translational motion, which allows the shank to move linearly along the sagittal/vertical plane, which locks and unlocks the knee, and rotational motion for the shank to swing when unlocked. The knee block, which is disposed at the top of the shank, has a spur gear that locks with a matching gear rack on the top plate of the knee housing. The side plates for the knee housing have a linear path that makes for the translational motion. During heel strike, the stopper in the front plate of the knee housing positions the shank in a straight position. When the user applies their weight for initiating stance phase, the knee block traverses up the path and the spur gear meshes with the matching rack, locking the knee. |
| FILED | Thursday, August 02, 2018 |
| APPL NO | 16/053136 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) Original (OR) Class A61F 2/68 (20130101) A61F 2002/607 (20130101) A61F 2002/6836 (20130101) A61F 2002/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702474 | Sailor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael J. Sailor (La Jolla, California); Byungji Kim (Cambridge, Massachusetts); Jinyoung Kang (La Jolla, California) |
| ABSTRACT | The disclosure describes a fusogenic liposome-coated porous silicon nanoparticles for high loading efficiency of anionic payloads (small molecules, dyes, nucleic acids), and for non-endocytic delivery of hydrophilic and lipophilic payloads by membrane fusion. The liposome coating can be further modified with targeting peptides or antibodies via covalent binding chemistry between the ligands and functionalized poly(ethylene glycol). The surface moieties can be transferred to the cellular membrane surface by fusogenic uptake. The composition of the disclosure can be applied in the treatment of diseases by delivering entrapped/encapsulated payloads. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/741649 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 31/713 (20130101) A61K 47/64 (20170801) A61K 47/6923 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702572 | Evilevitch |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alex Evilevitch (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are methods of suppressing viral nucleic acid, e.g. double-stranded (ds) DNA, genome release from or packaging of viruses having their nucleic acid genome packaged under stress in their capsid, and compositions useful for that purpose. The methods alter the ionic environment of the nucleic acid within the capsid and thereby prevent release of, and/or interfere with packaging of the viral genome. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419553 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0043 (20130101) A61K 9/0046 (20130101) A61K 31/08 (20130101) A61K 31/08 (20130101) A61K 31/14 (20130101) A61K 31/14 (20130101) A61K 31/16 (20130101) A61K 31/16 (20130101) A61K 31/132 (20130101) A61K 31/185 (20130101) A61K 31/185 (20130101) A61K 31/194 (20130101) A61K 31/194 (20130101) A61K 31/198 (20130101) A61K 31/198 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 5/1019 (20130101) C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702574 | Soliman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Christopher So (Henderson, Nevada); Howard P. Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone. |
| FILED | Saturday, February 11, 2017 |
| APPL NO | 15/430449 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 47/60 (20170801) A61K 47/551 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702630 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Jennifer A. Lewis (Cambridge, Massachusetts); Kimberly A. Homan (Somerville, Massachusetts); David B. Kolesky (Cambridge, Massachusetts); Ryan L. Truby (Boston, Massachusetts); Mark A. Skylar-Scott (Brookline, Massachusetts) |
| ABSTRACT | A 3D printed tubular construct, such as a nephron, with or without embedded vasculature as well as methods of printing tubular tissue constructs are described. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/567570 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/04 (20130101) A61F 2240/002 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3633 (20130101) A61L 27/3675 (20130101) A61L 27/3804 (20130101) Original (OR) Class A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3878 (20130101) A61L 27/3891 (20130101) A61L 2300/62 (20130101) A61L 2300/64 (20130101) A61L 2400/08 (20130101) A61L 2430/26 (20130101) A61L 2430/32 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702803 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Joohoon Kang (Evanston, Illinois) |
| ABSTRACT | Separation of rhenium disulfide nanomaterials and related fluid density gradient media. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/800666 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 21/26 (20130101) Original (OR) Class B01D 21/283 (20130101) Flotation; Differential Sedimentation B03D 3/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 47/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/02 (20130101) C01P 2004/04 (20130101) C01P 2004/20 (20130101) C01P 2004/30 (20130101) C01P 2004/61 (20130101) C01P 2006/10 (20130101) C01P 2006/40 (20130101) C01P 2006/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703637 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois) |
| ABSTRACT | A boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension and a method for preparation thereof. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 15/430885 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703711 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ACELOT, INC. (Santa Barbara, California) |
| ASSIGNEE(S) | Acelot, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Ambuj K. Singh (Santa Barbara, California); Christian A. Lang (Santa Barbara, California) |
| ABSTRACT | The present invention provides small molecule drugs and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of Aβ42 oligomers in a subject. It further provides a method of reducing formation of or disrupting Aβ42 oligomers in a subject, the method comprising the step of administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/350344 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/131 (20130101) A61K 31/135 (20130101) A61K 31/137 (20130101) Acyclic or Carbocyclic Compounds C07C 211/27 (20130101) C07C 211/28 (20130101) C07C 211/29 (20130101) C07C 217/60 (20130101) C07C 223/02 (20130101) C07C 233/43 (20130101) Original (OR) Class C07C 271/18 (20130101) Heterocyclic Compounds C07D 207/06 (20130101) C07D 295/15 (20130101) C07D 295/135 (20130101) C07D 319/18 (20130101) C07D 413/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703777 | Kirshenbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Kent Kirshenbaum (New York, New York); Timothy W. Craven (Randolph, New Jersey); Richard Bonneau (New York, New York) |
| ABSTRACT | Miniature protein scaffolds and compositions thereof (e.g., vaccine formulations) and methods of using same are described herein. In a particular embodiment, the miniature protein scaffold comprises an isolated β-strand connected via a loop to a left-handed poly proline type-II (PPII) helix formed in the absence of proline residues. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/879872 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 7/08 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2318/10 (20130101) C07K 2318/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704052 | Medina-Bolivar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arkansas State University Jonesboro (State University, Arkansas) |
| ASSIGNEE(S) | Arkansas State University Jonesboro (State University, Arkansas); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Luis Fabricio Medina-Bolivar (Jonesboro, Arkansas); Tianhong Yang (Jonesboro, Arkansas); Keithanne Mockaitis (Indianapolis, Indiana) |
| ABSTRACT | The process and system led to the identification of prenyltransferase genes from elicitor-treated peanut hairy roots. One of the prenyltransferases, AhR4DT-1 catalyzes a key reaction involved in the biosynthesis of prenylated stilbenoids, in which resveratrol is prenylated at its C-4 position to form arachidin-2, while another, AhR3′DT-1, was able to add the prenyl group to C-3′ of resveratrol. Each of these prenyltransferases has a high specificity for stilbenoid substrates, and their subcellular location in the plastid was confirmed by fluorescence microscopy. Structure analysis of the prenylated stilbenoids suggest that these two prenyltransferase activities represent the first committed steps in the biosynthesis of a large number of prenylated stilbenoids and their derivatives in peanut. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625450 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) C12N 15/8243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704056 | Cutler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sean R. Cutler (Riverside, California); Assaf Mosquna (Rehovot, Israel) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sean R. Cutler (Riverside, California); Assaf Mosquna (Rehovot, Israel) |
| ABSTRACT | The present invention provides for compositions comprising mutated PYR/PYL receptor polypeptides that bind to a type 2 protein phosphatase in the absence of abscisic acid. The present invention further provides for methods of making and using the mutated PYR/PYL receptor polypeptides. |
| FILED | Tuesday, June 19, 2012 |
| APPL NO | 14/126774 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704060 | Gersbach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Charles A. Gersbach (Durham, North Carolina); Isaac B. Hilton (Durham, North Carolina); Pablo Perez-Pinera (Lynn, Massachusetts); Ami M. Kabadi (Durham, North Carolina); Pratiksha I. Thakore (Durham, North Carolina); David G. Ousterout (Atlanta, Georgia); Joshua B. Black (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle. |
| FILED | Thursday, June 05, 2014 |
| APPL NO | 14/895316 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/005 (20130101) A61K 48/0058 (20130101) Peptides C07K 14/4708 (20130101) C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2740/16043 (20130101) C12N 2800/40 (20130101) C12N 2840/20 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704091 | Schnable et al. |
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| FUNDED BY |
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| APPLICANT(S) | Data2Bio (Ames, Iowa) |
| ASSIGNEE(S) | Data2Bio (Ames, Iowa) |
| INVENTOR(S) | Patrick S. Schnable (Ames, Iowa); Sanzhen Liu (Ames, Iowa); Wei Wu (Johnston, Iowa) |
| ABSTRACT | Provided herein is technology relating to genotyping and particularly, but not exclusively, to methods for genotyping one or more organisms by genome sequencing. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/917977 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/683 (20130101) C12Q 1/683 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705063 | Campanella et al. |
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| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Ian Martin (Sharon, Massachusetts); Joseph G. Michels (New York, New York); Nathan Pallo (Somerville, Massachusetts); Peter Quigley (Duxbury, Massachusetts) |
| ABSTRACT | An apparatus for sampling landfill gas from a landfill flowing through a pipe. The apparatus may comprise: an enclosure configured to receive a section of the pipe; a gas sampling port in the section of the pipe; at least one sensor device disposed in a region of the enclosure, the at least one sensor being coupled to the section of the pipe through the gas sampling port; and thermal insulation positioned to retain heat from the section of the pipe in the region of the enclosure. A method of operating a landfill gas recovery system. The method may comprise: flowing gas from a well riser pipe through a sampling subsystem to a collection system; and heating a portion of the sampling subsystem with the gas flowing from the well riser pipe to the collection system. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/464236 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) B09B 3/0016 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 36/00 (20130101) E21B 36/003 (20130101) E21B 47/06 (20130101) E21B 47/10 (20130101) E21B 47/065 (20130101) E21B 49/08 (20130101) E21B 2049/085 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2294 (20130101) G01N 33/004 (20130101) G01N 33/0006 (20130101) Original (OR) Class G01N 33/0036 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/20 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/20 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705085 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ly James Lee (Columbus, Ohio); Kwang Joo Kwak (Dublin, Ohio); Bo Yu (Zhejiang Province, China PRC); Yun Wu (Columbus, Ohio); Andrew Lee (Columbus, Ohio) |
| ABSTRACT | Disclosed are compositions and methods for the use of lipoplex nanoparticle chips and arrays in the detection of/diagnosis of a disease or condition. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/279545 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5432 (20130101) G01N 33/56983 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/52 (20180101) Y02A 50/59 (20180101) Y02A 50/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705589 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Jie Gu (Evanston, Illinois); Russ Joseph (Evanston, Illinois) |
| ABSTRACT | A system includes an ARM core processor, a programmable regulator, a compiler, and a control unit, where the compiler uses a performance association outcome to generate a 2-bit regulator control values encoded into each individual instruction. The system can provide associative low power operation where instructions govern the operation of on-chip regulators or clock generator in real time. Based on explicit association between long delay instruction patterns and hardware performance, an instruction based power management scheme with energy models are formulated for deriving the energy efficiency of the associative operation. An integrated voltage regulator or clock generator is dynamically controlled based on instructions existing in the current pipeline stages leading to additional power saving. A compiler optimization strategy can further improve the energy efficiency. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604098 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/08 (20130101) G06F 1/324 (20130101) G06F 1/3243 (20130101) Original (OR) Class G06F 1/3296 (20130101) G06F 8/41 (20130101) G06F 9/3836 (20130101) G06F 9/30083 (20130101) G06F 9/30145 (20130101) G06F 9/30185 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/126 (20180101) Y02D 10/152 (20180101) Y02D 10/172 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705610 | Colgate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James E. Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois); Craig Shultz (Chicago, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | James E. Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois); Craig Shultz (Chicago, Illinois) |
| ABSTRACT | A touch interface device that produces tactile and audio output comprising a touch surface, an first electrode coupled to the touch surface that receives a first haptic/audio output potential, a second electrode coupled to a low impedance return path to the device, the first and second electrodes being configured such that when both the first and second electrodes are touched by an appendage of a user, a current flows between the first and second electrodes and the appendage, where the current creates an electric field that imparts a controlled electrostatic force at interfaces of the first electrode and the appendage, and wherein the electrostatic force provides tactile feedback to the appendage of the user and causes vibration in the surrounding air that is audible to the user. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/186056 |
| ART UNIT | 2625 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) Original (OR) Class G06F 3/16 (20130101) G06F 3/041 (20130101) G06F 3/043 (20130101) G06F 3/044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705611 | Meyer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | David J. Meyer (Chicago, Illinois) |
| ABSTRACT | This disclosure provides designer interfaces that present condensed representations of texture functions, the representations displaying selected control points that manipulate the representations, an algorithm that computes a texture function based on the positions of said selected control points, and the texture function generating a signal to control a force on an appendage of a user that touches a tactile surface, and methods of using the designer interfaces. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 15/514271 |
| ART UNIT | 2177 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) Original (OR) Class G06F 3/16 (20130101) G06F 3/017 (20130101) G06F 3/045 (20130101) G06F 3/0414 (20130101) G06F 3/0488 (20130101) G06F 3/04847 (20130101) G06F 2203/014 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706185 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Pingbo Tang (Tempe, Arizona); Vamsi Kalasapudi (Tempe, Arizona) |
| ABSTRACT | Systems and methods for automated spatial change detection and control of buildings and construction sites using three-dimensional laser scanning data are disclosed. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 15/497787 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 2600/10 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 15/002 (20130101) Electric Digital Data Processing G06F 16/9024 (20190101) G06F 30/13 (20200101) Original (OR) Class G06F 30/18 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) G06Q 50/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706258 | Javidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs Mansfield, Connecticut); Adam Markman (Orange, Connecticut); Siddharth Rawat (Mansfield, Connecticut); Satoru Komatsu (Mansfield, Connecticut) |
| ABSTRACT | Embodiments of the present disclosure include systems and methods for cell identification using a lens-less cell identification sensor. Randomly distributed cells can be illuminated by a light source such as a laser. The object beam can be passed through one or more diffusers. Pattern recognition is applied on the captured optical signature to classify the cells. For example, features can be extracted and a trained classifier can be used to classify the cells. The cell classes can be accurately identified even when multiple cells of the same class are inspected. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902655 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0278 (20130101) G02B 21/06 (20130101) G02B 21/0008 (20130101) G02B 21/365 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00134 (20130101) Original (OR) Class G06K 9/00147 (20130101) G06K 9/2036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707481 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Se-Hee Lee (Denver, Colorado); Jerry Martin (Arvada, Colorado); Vinay Bhat (Arvada, Colorado); Daniela Molina Piper (Denver, Colorado); Tyler Evans (Denver, Colorado) |
| ABSTRACT | The disclosure includes a composition of matter including a film formed on substantially all nSi-cPAN particles included in an electrode, the film including fluorine, oxygen, sulfur, carbon and lithium. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 15/522256 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/622 (20130101) H01M 10/0525 (20130101) H01M 10/0566 (20130101) H01M 2004/021 (20130101) H01M 2300/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707581 | Mohtashami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Yahya Mohtashami (Madison, Wisconsin); Nader Behdad (Oregon, Wisconsin); Susan C. Hagness (Madison, Wisconsin) |
| ABSTRACT | An antenna includes a first dipole arm and a second dipole arm. The first dipole arm is connected to a first conductor and is formed of a first conducting material. The first dipole arm extends in an axial direction from the first conductor. The second dipole arm is connected to a second conductor that is distinct from the first conductor and is formed of a second conducting material. The second dipole arm extends in the axial direction from the second conductor and is wound around the first dipole arm to form a number of loops. The second dipole arm does not contact the first dipole arm. An axial length of the second dipole arm in the axial direction is less than 90% of an axial length of the first dipole arm in the axial direction. |
| FILED | Wednesday, January 03, 2018 |
| APPL NO | 15/860943 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/526 (20130101) H01Q 9/14 (20130101) H01Q 9/18 (20130101) H01Q 9/20 (20130101) Original (OR) Class H01Q 11/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707649 | Yun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Seok Hyun Yun (Belmont, Massachusetts) |
| ABSTRACT | Disclosed are photonic particles and methods of using particles in biological samples. The particles are configured to emit laser light when energetically stimulated by, e.g., a pump source. The particles may include a gain medium with inorganic materials, an optical cavity with high refractive index, and a coating with organic materials. The particles may be smaller than 3 microns along their longest axes. The particles may attach to each other to form, e.g., doublets and triplets. The particles may be injection-locked by coupling an injection beam into a particle while pumping so that an injection seed is amplified to develop into laser oscillation. A microscopy system may include a pump source, beam scanner, spectrometer with resolution of less than 1 nanometer and acquisition rate of more than 1 kilohertz, and spectral analyzer configured to distinguish spectral peaks of laser output from broadband background. |
| FILED | Monday, June 05, 2017 |
| APPL NO | 16/306278 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2003/2826 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 2015/1006 (20130101) G01N 2021/6439 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/091 (20130101) H01S 3/169 (20130101) H01S 3/213 (20130101) H01S 3/0604 (20130101) H01S 5/36 (20130101) H01S 5/40 (20130101) H01S 5/041 (20130101) H01S 5/1025 (20130101) H01S 5/1067 (20130101) Original (OR) Class H01S 5/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707947 | Paramesh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania) |
| ABSTRACT | A reconfigurable, multi-band hybrid beamforming architecture is introduced. The present invention is related to a Cartesian-Combining architecture to efficiently implement RF beamforming for a single downconversion chain employing direct downconversion in which the Cartesian-Combining architecture is extended to hybrid beamforming and to heterodyne downconversion. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/163374 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/16 (20130101) H04B 1/0028 (20130101) H04B 1/0078 (20130101) H04B 7/088 (20130101) Original (OR) Class H04B 7/0413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10708170 | Sen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Porperty I, L.P. (Atlanta, Georgia) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); The Trustees of Indiana University (Indianapolis, Indiana); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Subhabrata Sen (Westfield, New Jersey); Zhuoqing Morley Mao (Ann Arbor, Michigan); Feng Qian (Bloomington, Indiana); Yihua Guo (Mountain View, California) |
| ABSTRACT | A request for a chunk of data is received from an application executing on a remote device. The chunk of data is split into a plurality of packets including a first packet and a second packet. A first sub-flow is selected to transport the first packet to the remote device and a second sub-flow is selected to transport the second packet. The first sub-flow is decoupled from the second sub-flow. A first stop time is selected for the first sub-flow and a second stop time is selected for the second sub-flow. The first stop time determines when the first sub-flow will complete at the remote device and the second stop time determines when the second sub-flow will complete at the remote device. The first stop time and the second stop time are selected so that the first sub-flow and the second sub-flow will complete simultaneously at the remote device. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 15/921238 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/14 (20130101) Original (OR) Class H04L 45/24 (20130101) H04L 45/44 (20130101) Wireless Communication Networks H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10708995 | Ku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Pei-Cheng Ku (Ann Arbor, Michigan); Kunook Chung (Ann Arbor, Michigan); Brandon Demory (Whitmore Lake, Michigan) |
| ABSTRACT | Additive color mixing across the visible spectrum was demonstrated from a light emitting diode (LED) pixel comprising of red, green, and blue subpixels monolithically integrated and enabled by local strain engineering. The device was fabricated using a top-down approach on a metal-organic chemical vapor deposition-grown sample consisting of a typical LED epitaxial stack. The three color subpixels were defined in a single lithographic step. The device was characterized for its electrical properties and emission spectra under an uncooled condition, which is desirable in practical applications. The color mixing was controlled by pulse width modulation and the degree of color control was also characterized. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977011 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/156 (20130101) H01L 33/06 (20130101) H01L 33/08 (20130101) H01L 33/24 (20130101) H01L 33/32 (20130101) H01L 33/58 (20130101) H01L 33/0075 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/20 (20200101) H05B 45/40 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48083 | Sen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Pradeep Sen (Goleta, California); Aliakbar Darabi (Newcastle, Washington) |
| ABSTRACT | The invention produces a higher quality image from a rendering system based on a relationship between the output of a rendering system and the parameters used to compute them. Specifically, noise is removed in rendering by estimating the functional dependency between sample features and the random inputs to the system. Mutual information is applied to a local neighborhood of samples in each part of the image. This dependency is then used to reduce the importance of certain scene features in a cross-bilateral filter, which preserves scene detail. The results produced by the invention are computed in a few minutes thereby making it reasonably robust for use in production environments. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/143331 |
| ART UNIT | 3992 — Central Reexamination Unit (Electrical) |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/00 (20130101) G06T 5/001 (20130101) Original (OR) Class G06T 5/50 (20130101) G06T 15/503 (20130101) G06T 2200/12 (20130101) G06T 2207/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10702850 | Long et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey R. Long (Oakland, California); Jarad A. Mason (Chicago, Illinois); Mercedes K. Taylor (Oakland, California); Julia Oktawiec (Berkeley, California) |
| ABSTRACT | The disclosure provides for adsorbents with stepped isotherms for gas storage applications. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/766495 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Separation B01D 2253/204 (20130101) B01D 2256/16 (20130101) B01D 2256/245 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/3425 (20130101) B01J 20/3491 (20130101) B01J 20/28066 (20130101) Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 15/03006 (20130101) B60K 2015/03315 (20130101) B60K 2015/03322 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/0015 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) C07F 15/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702852 | Janke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Christopher J. Janke (Oliver Springs, Tennessee); Richard T. Mayes (Knoxville, Tennessee); Sadananda Das (Kissimmee, Florida); Sheng Dai (Knoxville, Tennessee) |
| ABSTRACT | A method of producing a functionalized material that extracts metal ions from solution, the method comprising: (i) providing a precursor material having nitrile groups appended to its surface; and (ii) reacting said nitrile groups with hydroxylamine or a derivative thereof in the presence of a polar aprotic solvent at a temperature of 60-80° C. for at least 1 hour, to convert at least a portion of said nitrile groups to amidoxime and imide dioxime groups, followed by reaction with a base capable of hydrolyzing any remaining nitrile groups to carboxylic acid groups; wherein said functionalized material has a higher uranium absorption capacity than a functionalized material produced under same conditions except that the nitrile groups are reacted with hydroxylamine in only a protic solvent. The invention is also directed to functionalized materials produced by the above-described method, and methods for using the functionalized material for extracting metal ions from metal-containing solutions. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625276 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class B01J 20/321 (20130101) B01J 20/3085 (20130101) B01J 20/3217 (20130101) B01J 20/3265 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 2101/006 (20130101) C02F 2101/20 (20130101) C02F 2103/08 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 255/02 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/247 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/46 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/008 (20130101) D06M 11/38 (20130101) D06M 13/368 (20130101) D06M 14/10 (20130101) D06M 14/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702862 | Erdemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Ali Erdemir (Naperville, Illinois); Osman Eryilmaz (Plainfield, Illinois); Jair Giovanni Ramirez Gonzalez (San Jose, California) |
| ABSTRACT | A nanocomposite coating that in turn extract self-replenishing (or -healing), superlubricious carbon film directly from natural gas or hydrocarbon gas in mechanical systems. The coating deposits on sealing and sliding surfaces reducing friction and wear. The result is a reduction in inefficiency, machine breakdown, and adverse environmental impact. |
| FILED | Friday, April 13, 2018 |
| APPL NO | 15/952623 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/002 (20130101) B01J 37/0225 (20130101) Original (OR) Class Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 103/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/0605 (20130101) C23C 28/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10702925 | Everhart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Wesley Everhart (Kansas City, Missouri); Benjamin Brown (Kansas City, Missouri); Dan Bowen (Kansas City, Missouri) |
| ABSTRACT | A composite material comprising a metal matrix and nanocellulose supplement. The metal matrix is formed of a metal base material and may be monolithic throughout the composite material. The nanocellulose supplement improves a material property of the metal matrix and is formed of a nanocellulose supplement material dispersed in the metal base material. Importantly, the nanocellulose supplement material does not become damaged when the composite material is formed. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/256069 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 21/00 (20130101) B22D 25/06 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/10 (20130101) B22F 7/008 (20130101) Original (OR) Class B22F 9/04 (20130101) B22F 2301/15 (20130101) B22F 2301/052 (20130101) B22F 2301/058 (20130101) B22F 2301/205 (20130101) B22F 2302/45 (20130101) B22F 2998/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703637 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois) |
| ABSTRACT | A boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension and a method for preparation thereof. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 15/430885 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703770 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jian Sun (Albany, California); Tanmoy Dutta (Berkeley, California); Parthasarathi Ramakrishnan (Fremont, California); Blake A. Simmons (San Francisco, California); Seema Singh (Mountain House, California) |
| ABSTRACT | The present invention provides for a method for dissolving and/or depolymerizing lignin comprising: (a) providing a composition comprising lignin, (b) contacting the composition with a strong hydrogen donor, such as a polyol, to form a first solution, (c) incubating the first solution at a temperature equal to or less than 100° C., whereby at least 20% by weight of the lignin is dissolved, (d) optionally introducing an oxidation agent to the first solution to form a second solution, wherein the temperature of the second solution is equal to or less than 100° C., whereby lignin is depolymerized, and (e) optionally introducing an anti-solvent to the second solution to precipitate the depolymerized lignin. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615777 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 302/01004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703968 | Riddle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Catherine Lynn Riddle (Idaho Falls, Idaho); Douglas W. Akers (Idaho Falls, Idaho); Dawn M. Scates (Idaho Falls, Idaho); Rick L. Demmer (Idaho Falls, Idaho) |
| ABSTRACT | Scintillation compositions comprising a gadolinium compound and a scintillation compound in a polymer matrix precursor. The scintillation compound comprises strontium diiodide, fac-tris(2-phenylpyridine)iridium (Ir(ppy)3), a quinine compound, or combinations thereof, or 2-(4-biphenylyl)-5 phenyl-1,3,4-oxadiazole (PBD), 2-(4-tert-butylphenyl)-5-(4-phenylphenyl)-1,3,4-oxadiazole (b-PBD), 2,5-diphenyl oxazole (PPO), 1,4-bis(5-phenyloxazol-2-yl) benzene (POPOP), or combinations thereof. Hydrogels comprising the gadolinium compound and scintillation compound in a polymer matrix are also disclosed, as are related systems and methods. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/890837 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) Original (OR) Class C09K 11/616 (20130101) C09K 2211/10 (20130101) C09K 2211/182 (20130101) C09K 2211/185 (20130101) Measurement of Nuclear or X-radiation G01T 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704034 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes Inc. (Davis, California) |
| INVENTOR(S) | Lan Tang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Yu Zhang (Beijing, China PRC); Junxin Duan (Beijing, China PRC) |
| ABSTRACT | The present invention provides isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, October 26, 2012 |
| APPL NO | 14/346227 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2482 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704122 | Schelter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Eric J. Schelter (Philadelphia, Pennsylvania); Justin A. Bogart (Brooklyn, New York) |
| ABSTRACT | A method is provided for separating mixtures of different rare earth metals using a ligand having a size-sensitive molecular aperture. The present invention meets the needs in the field by providing method of separating and purifying rare earth metals. The object of this invention is to separate and purify rare earth metals, e.g., the more valuable Dy away from Nd, in mixtures containing such metals using a simple chemical process without the need for countercurrent liquid-liquid separations. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 15/321209 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/20 (20130101) C22B 3/44 (20130101) C22B 7/006 (20130101) C22B 59/00 (20130101) Original (OR) Class Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/22 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704123 | Brown et al. |
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| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Michael Alexander Brown (Chicago, Illinois); Jerry A. Nolen, Jr. (Chicago, Illinois); David Alan Rotsch (Montgomery, Illinois) |
| ABSTRACT | The invention provides a method for isolating medical isotopes, the method having the steps of dissolving titanium nuclear targets to create a solution; contacting the solution with a resin so as to retain the isotopes on the resin and generate an eluent containing titanium; contacting the isotope-containing resin with acid of a first concentration to remove impurities from the resin; and contacting the isotope-containing resin with an acid of a second concentration to remove isotope from the resin. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502922 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 60/0295 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704152 | Holland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Justin M. Holland (Clinton, Tennessee); John W. Freiderich (Oak Ridge, Tennessee) |
| ABSTRACT | Systems and methods for producing metal chloride MIClx from metal MI without the use of HCl and/or Cl2 gases, including: a bath vessel holding conductive fluid; an anode disposed in the conductive fluid, the anode including metal MI; a cathode assembly disposed in the conductive fluid, the cathode assembly including a cathode vessel including porous and non-porous portions, the non-porous portion holding sacrificial metal chloride MIICly substantially separate from metal chloride MIClx, wherein the cathode assembly includes a center lead disposed within the cathode vessel operable for delivering charge to sacrificial metal chloride MIICly; and a power supply coupling the anode and the cathode assembly, the power supply polarized to produce current flow in a direction that causes anodic dissolution of metal MI into the conductive fluid and deposition of metal MII within the cathode vessel. The systems and methods apply equally to producing metal halide MIXx. |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 15/868464 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/14 (20130101) C25B 1/26 (20130101) Original (OR) Class C25B 9/00 (20130101) C25B 9/04 (20130101) C25B 9/063 (20130101) C25B 11/035 (20130101) C25B 15/08 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/20 (20130101) C25C 3/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704153 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Peidong Yang (Kensington, California); Dohyung Kim (Albany, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peidong Yang (Kensington, California); Dohyung Kim (Albany, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to copper nanoparticle structures for reduction of carbon dioxide to multicarbon products. In one aspect, a method includes providing a plurality of copper nanoparticles. The plurality of copper nanoparticles are deposited on a support. The plurality of copper nanoparticles are transformed to a plurality of copper structures during an operation in which carbon dioxide is reduced. The plurality of copper nanoparticles on the support are used as a working electrode in an electrochemical cell during the operation. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840435 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 3/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/32 (20130101) C01P 2004/38 (20130101) C01P 2004/40 (20130101) C01P 2004/64 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/627 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 3/04 (20130101) C25B 11/12 (20130101) C25B 11/0447 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9041 (20130101) H01M 8/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704160 | Koeck et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Franz A. Koeck (Tempe, Arizona); Robert J. Nemanich (Scottsdale, Arizona) |
| ABSTRACT | Apparatuses and methods are provided for manufacturing diamond electronic devices. The apparatus includes a base comprising a water-block and a cover that at least partially covers the water-block. The apparatus includes a sample stage disposed on the base. The apparatus further includes a sample holder disposed on the sample stage and configured to accept a diamond substrate. The apparatus includes controlled thermal interfaces between water-block, sample stage, sample holder and diamond substrate. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591671 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/00 (20130101) C23C 16/44 (20130101) C23C 16/46 (20130101) C23C 16/463 (20130101) C23C 16/466 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/00 (20130101) C30B 25/02 (20130101) C30B 25/10 (20130101) Original (OR) Class C30B 25/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 117/00 (20150115) Y10T 117/10 (20150115) Y10T 117/1016 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704429 | Mariuz et al. |
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| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (, Barbados) |
| INVENTOR(S) | Robert M. Mariuz (Pittsford, New York); Kevin R. Keegan (Hilton, New York); Peter R. Charles (Rochester, New York); Hermes A. Fernandez (Pittsford, New York) |
| ABSTRACT | A rocker arm includes an outer arm and an inner arm which selectively pivots relative to the outer arm. The rocker arm also includes a lock pin which is displaced along a lock pin axis between a coupled position and a decoupled position. The rocker arm also includes a linkage and a linkage guide which guides the linkage along a linkage axis. One surface of the linkage engages an actuator while another surface of the linkage engages the lock pin such that the linkage translates motion from the actuator to motion of the lock pin. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/143793 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cyclically Operating Valves for Machines or Engines F01L 1/181 (20130101) Original (OR) Class F01L 1/2405 (20130101) F01L 13/0005 (20130101) F01L 13/0015 (20130101) F01L 2001/186 (20130101) F01L 2001/467 (20130101) F01L 2105/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704786 | Laster et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
| INVENTOR(S) | Walter Ray Laster (Oviedo, Florida); Timothy A. Fox (Hamilton, Canada); Robert H. Bartley (Oviedo, Florida) |
| ABSTRACT | A fuel injector for injecting alternate fuels having a different energy density in a gas turbine is provided. A first fuel supply channel (18) may be fluidly coupled to a radial passage (22) in a plurality of vanes (20) that branches into passages (24) (e.g., axial passages) to inject a first fuel without jet in cross-flow injection. This may be effective to reduce flashback in fuels having a relatively high flame speed. A mixer (30) with lobes (32) for injection of a second fuel may be arranged at the downstream end of a fuel delivery tube (12). A fuel-routing structure (38) may be configured to route the second fuel within a respective lobe so that fuel injection of the second fuel takes place radially outwardly relative to a central region of the mixer. This may be conducive to an improved (e.g., a relatively more uniform) mixing of air and fuel. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 15/540405 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Burners F23D 14/24 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/14 (20130101) Original (OR) Class F23R 3/36 (20130101) F23R 3/286 (20130101) F23R 2900/00002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704846 | Alahyari et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Abbas A. Alahyari (Glastonbury, Connecticut); Craig R. Walker (S. Glastonbury, Connecticut); Scott Alan Eastman (Glastonbury, Connecticut); Catherine Thibaud (South Windsor, Connecticut) |
| ABSTRACT | A heat exchanger includes a metal tube and a composite polymer fin in thermal contact with the metal tube. The fin is formed of a polymer and a thermally conductive filler such that the fin has a thermal conductivity greater than or equal to 0.5 Watts per meter Kelvin. |
| FILED | Monday, June 12, 2017 |
| APPL NO | 15/620433 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Methods of Steam Generation; Steam Boilers F22B 37/101 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/053 (20130101) F28D 1/0535 (20130101) F28D 1/05316 (20130101) F28D 1/05383 (20130101) F28D 7/0041 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/12 (20130101) F28F 1/32 (20130101) F28F 1/126 (20130101) F28F 1/325 (20130101) F28F 3/022 (20130101) F28F 13/185 (20130101) F28F 21/062 (20130101) Original (OR) Class F28F 21/067 (20130101) F28F 21/081 (20130101) F28F 2215/00 (20130101) F28F 2215/04 (20130101) F28F 2215/06 (20130101) F28F 2245/04 (20130101) F28F 2255/06 (20130101) F28F 2260/02 (20130101) F28F 2275/10 (20130101) F28F 2275/025 (20130101) F28F 2275/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704995 | Kertesz et al. |
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| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Vilmos Kertesz (Oak Ridge, Tennessee); Gary J. Van Berkel (Oak Ridge, Tennessee) |
| ABSTRACT | A system for sampling a sample material includes a device for directing sample into a capture probe. A probe includes an outer probe housing having an open end. A liquid supply conduit has an outlet positioned to deliver liquid to the open end. An exhaust conduit removes liquid from the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust system can be in fluid connection with the liquid exhaust conduit for removing liquid from the liquid exhaust conduit at a second volumetric flow rate, which exceeds the first volumetric flow rate such that gas with sample is withdrawn with the liquid. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/517340 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/24 (20130101) Original (OR) Class G01N 2001/028 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/164 (20130101) H01J 49/0418 (20130101) H01J 49/0463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705962 | Beckmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Carl J. Beckmann (Newton, Massachusetts); Robert G. Blankenship (Tacoma, Washington); Chyi-Chang Miao (Sharon, Massachusetts); Chitra Natarajan (Flushing, New York); Anthony-Trung D. Nguyen (Castro Valley, California) |
| ABSTRACT | Embodiment of this disclosure provides a mechanism to use a portion of an inactive processing element's private cache as an extended last-level cache storage space to adaptively adjust the size of shared cache. In one embodiment, a processing device is provided. The processing device comprising a cache controller is to identify a cache line to evict from a shared cache. An inactive processing core is selected by the cache controller from a plurality of processing cores associated with the shared cache. Then, a private cache of the inactive processing core is notified of an identifier of a cache line associated with the shared cache. Thereupon, the cache line is evicted from the shared cache to install in the private cache. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/850865 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/084 (20130101) Original (OR) Class G06F 12/123 (20130101) G06F 12/127 (20130101) G06F 12/128 (20130101) G06F 12/0811 (20130101) G06F 12/0862 (20130101) G06F 12/0868 (20130101) G06F 12/0897 (20130101) G06F 2212/283 (20130101) G06F 2212/621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705972 | Farmahini-Farahani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Amin Farmahini-Farahani (Santa Clara, California); Alexander D. Breslow (Sunnyvale, California); Nuwan S. Jayasena (Sunnyvale, California) |
| ABSTRACT | Systems, apparatuses, and methods for determining preferred memory page management policies by software are disclosed. Software executing on one or more processing units generates a memory request. Software determines the preferred page management policy for the memory request based at least in part on the data access size and data access pattern of the memory request. Software conveys an indication of a preferred page management policy to a memory controller. Then, the memory controller accesses memory for the memory request using the preferred page management policy specified by software. |
| FILED | Tuesday, September 13, 2016 |
| APPL NO | 15/264400 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1009 (20130101) Original (OR) Class G06F 13/00 (20130101) G06F 13/1668 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706181 | Hamlet |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jason Hamlet (Albuquerque, New Mexico) |
| ABSTRACT | Described herein are various technologies pertaining to randomizing logic associated with dangling nodes in a digital circuit design. A dangling node is an input to or output from a logic gate in the digital circuit design that is identified as not impacting a desired output of the digital circuit design. Randomizing the logic associated with a dangling node can include deleting a logic gate, adding a logic gate, replacing a logic gate with another logic gate, etc. Randomizing the logic associated with the dangling node prevents hardware trojans that may have been inserted into the circuit design from being implemented in a circuit that is generated based upon the design. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/846571 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/85 (20130101) Original (OR) Class G06F 30/327 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706323 | Liebman |
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| FUNDED BY |
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| APPLICANT(S) | SparkCognition, Inc. (Austin, Texas) |
| ASSIGNEE(S) | SPARKCOGNITION, INC. (Austin, Texas) |
| INVENTOR(S) | Elad Liebman (Austin, Texas) |
| ABSTRACT | A method includes determining a feature importance ranking for each pair of clusters of a plurality of clusters to generate a first plurality of feature importance rankings. The method further includes determining a feature importance ranking between a particular data element and each cluster to generate a second plurality of feature importance rankings. A distance value associated with each pair of clusters of the plurality of clusters is determined to generate a plurality of distance values, and a probability value associated with each data element is determined to generate a plurality of probability values. The method further includes weighting the first plurality of feature importance rankings based on the plurality of distance values to determine a first plurality of weighted feature importance rankings and weighting the second plurality of feature importance rankings based on the plurality of probability values to determine a second plurality of weighted feature importance rankings. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/559998 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/623 (20130101) Original (OR) Class G06K 9/6218 (20130101) G06K 9/6272 (20130101) G06K 9/6277 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10706987 | Zidan et al. |
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| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Ragaiy Zidan (Aiken, South Carolina); Joseph A. Teprovich, Jr. (Aiken, South Carolina); Hector R. Colon-Mercado (Aiken, South Carolina); Scott D. Greenway (Aiken, South Carolina) |
| ABSTRACT | A LiBH4—C60 nanocomposite that displays fast lithium ionic conduction in the solid state is provided. The material is a homogenous nanocomposite that contains both LiBH4 and a hydrogenated fullerene species. In the presence of C60, the lithium ion mobility of LiBH4 is significantly enhanced in the as prepared state when compared to pure LiBH4. After the material is annealed the lithium ion mobility is further enhanced. Constant current cycling demonstrated that the material is stable in the presence of metallic lithium electrodes. The material can serve as a solid state electrolyte in a solid-state lithium ion battery. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937022 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/152 (20170801) C01B 32/156 (20170801) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) H01B 1/06 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/188 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) H01M 2300/0068 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707359 | Tombs et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eastman Kodak Company (Rochester, New York) |
| ASSIGNEE(S) | EASTMAN KODAK COMPANY (Rochester, New York) |
| INVENTOR(S) | Thomas Nathaniel Tombs (Rochester, New York); Todd Mathew Spath (Hilton, New York); Douglas Edward Garman (Webster, New York); Christopher B. Liston (Rochester, New York); Carolyn Rae Ellinger (Rochester, New York) |
| ABSTRACT | An electrode film is fabricated by using a flexographic printing system to print a first electrode pattern including a first set of parallel electrodes and a second electrode pattern including a second set of parallel electrodes onto a first surface of a transparent film using a catalytic ink, wherein elements of the first electrode pattern do not cross over elements of the second electrode pattern. The flexographic printing system prints a third electrode pattern including a third set of parallel electrodes onto a second surface of the transparent film using the catalytic ink, wherein the first, second and third sets of parallel electrodes are arranged in an interlaced pattern. A conductive metallic material is electrolessly plated onto the catalytic ink such that the elements of the first, second and third electrode patterns become conductive. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106062 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/0013 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/24 (20130101) Electric Digital Data Processing G06F 3/044 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707484 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Amprius, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Amprius, Inc. (Fremont, California) |
| INVENTOR(S) | Weijie Wang (Sunnyvale, California); Zuqin Liu (Sunnyvale, California); Song Han (Foster City, California); Jonathan Bornstein (Cupertino, California); Constantin Ionel Stefan (San Jose, California) |
| ABSTRACT | Provided herein are nanostructures for lithium ion battery electrodes and methods of fabrication. In some embodiments, a nanostructure template coated with a silicon coating is provided. The silicon coating may include a non-conformal, more porous layer and a conformal, denser layer on the non-conformal, more porous layer. In some embodiments, two different deposition processes, e.g., a PECVD layer to deposit the non-conformal layer and a thermal CVD process to deposit the conformal layer, are used. Anodes including the nanostructures have longer cycle lifetimes than anodes made using either a PECVD or thermal CVD method alone. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 15/887809 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) Original (OR) Class H01M 4/0428 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707536 | Visco et al. |
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| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | POLYPLUS BATTERY COMPANY (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Ian Wogan (Oakland, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Solid-state laminate electrode assemblies and various methods for making the solid-state laminate electrode assemblies involve a lithium metal layer reactively bonded to a lithium ion conducting sulfide glass layer. During manufacture, highly reactive surfaces of the lithium metal layer and the lithium ion conducting sulfide glass layer are maintained in its substantially unpassivated state until they have been reactively bonded. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/592102 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/0407 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/0585 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707755 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xin Zhang (Yorktown Heights, New York); Todd Edward Takken (Brewster, New York); Chung-shiang Wu (Chiba, Japan); Robert Matthew Senger (Tarrytown, New York); Rudolf Adriaan Haring (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York) |
| ABSTRACT | An apparatus is disclosed that includes a semiconductor device to control a power converter having two or more power FETs. The semiconductor device includes a gate signal generator configured to produce two or more gate signals able to drive the two or more FETs. The gate signal generator has programmable timing configuration parameters to control operation of the two or more gate signals, wherein the timing configuration parameters are digitally programmed via a memory in the semiconductor device. The memory may be implemented with fuses, other non-volatile memory or volatile memory. The parameters may be fixed or updated during a lifetime of the apparatus. A serial-to-parallel conversion may be used to input the parameters. Optimization methods may be performed to determine parameters considered to be optimal. The apparatus may also include the power converter. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257861 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/115 (20130101) H01L 27/11206 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/157 (20130101) Original (OR) Class Pulse Technique H03K 19/1737 (20130101) H03K 19/01855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48084 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OneD Material LLC (Palo Alto, California) |
| ASSIGNEE(S) | ONED MATERIAL LLC (Palo Alto, California) |
| INVENTOR(S) | Yimin Zhu (Fremont, California); Jay L. Goldman (Mountain View, California); Baixin Qian (Cupertino, California); Ionel C. Stefan (San Jose, California) |
| ABSTRACT | The present invention relates to SiC nanostructures, including SiC nanopowder, SiC nanowires, and composites of SiC nanopowder and nanowires, which can be used as catalyst supports in membrane electrode assemblies and in fuel cells. The present invention also relates to composite catalyst supports comprising nanopowder and one or more inorganic nanowires for a membrane electrode assembly. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/017678 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/925 (20130101) H01M 4/926 (20130101) H01M 4/8605 (20130101) H01M 4/8807 (20130101) H01M 8/1011 (20130101) H01M 2008/1095 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10702347 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | The Regents of the University of California (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Thomas Frederick (Lincoln, Nebraska); Lou Cubrich (Lincoln, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations and at least three degrees of freedom. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691087 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/37 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0024 (20130101) B25J 9/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704415 | Morin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Bruce L. Morin (Springfield, Massachusetts); Wesley K. Lord (South Glastonbury, Connecticut) |
| ABSTRACT | In accordance with one aspect of the disclosure, a gas turbine engine, method of using and designing such is disclosed. The gas turbine engine may comprise a fan including a plurality of blades, and a variable area fan nozzle. The fan may be configured to have a design point fan tip leading edge relative flow angle βADP, and may be further configured to have an off-design point fan tip leading edge relative flow angle β at an off-design fan operating point. The variable area fan nozzle may be configured to manipulate the amount of air flowing through the fan so that the absolute value of a difference between the design point fan tip leading edge relative flow angle βADP and the off-design point fan tip leading edge relative flow angle β is in a specified range. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/761689 |
| ART UNIT | 3748 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 5/141 (20130101) F01D 9/02 (20130101) F01D 17/14 (20130101) F01D 25/04 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/15 (20130101) F02K 1/16 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2260/96 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704571 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Pete Lynn (Oakland, California); Kevin Albert (San Francisco, California); Giancarlo Nucci (San Francisco, California); Tim Swift (Clovis, California); Maria Telleria (Redwood City, California); Loren Russell (Berkeley, California); Jonathan Pompa (Long Beach, California) |
| ABSTRACT | A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997337 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) Original (OR) Class F15B 15/202 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/06 (20130101) F16K 17/048 (20130101) F16K 31/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705001 | Bachalo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Artium Technologies, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Artium Technologies, Inc. (Sunnyvale, California) |
| INVENTOR(S) | William D. Bachalo (Los Altos Hills, California); Gregory A. Payne (Richland, Washington); Khalid Ibrahim (Hatfield, Pennsylvania); Michael J. Fidrich (San Jose, California); Julien Manin (Livermore, California) |
| ABSTRACT | An apparatus to provide multi-beam imaging of particles includes a plurality of vertical cavity surface emitting lasers (VCSELs) configured to generate a plurality of light beams that converge with each other to form a measurement volume within a particle field. The plurality of the VCSELs are configured to provide uniformity in a background illumination of the measurement volume. An imaging optics is coupled to at least one of the plurality of VCSELs. A digital camera is coupled to the imaging optics to obtain a shadow image of a particle passing through the measurement volume at a focal plane of the digital camera. A processor is coupled to the digital camera. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/959717 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0227 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/423 (20130101) H01S 5/06804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705296 | Stone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| ASSIGNEE(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| INVENTOR(S) | William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland) |
| ABSTRACT | An optical energy transfer and conversion system comprising a fiber spooler and an electrical power extraction subsystem connected to the spooler with an optical waveguide. Optical energy is generated at and transferred from a base station through fiber wrapped around the spooler, and ultimately to the power extraction system at a remote mobility platform for conversion to another form of energy. The fiber spooler may reside on the remote mobility platform which may be a vehicle, or apparatus that is either self-propelled or is carried by a secondary mobility platform either on land, under the sea, in the air or in space. |
| FILED | Monday, January 15, 2018 |
| APPL NO | 15/871739 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/00 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) E21B 47/135 (20200501) Optical Elements, Systems, or Apparatus G02B 6/3604 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4296 (20130101) G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4458 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/30 (20160201) H02J 50/90 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705297 | Stone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| ASSIGNEE(S) | Stone Aerospace, Inc. (Del Valle, Texas) |
| INVENTOR(S) | William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland) |
| ABSTRACT | A method of launching a spacecraft into low Earth orbit using a non-line-of-sight optical power transfer system. The method includes generating optical power at a base station and using an optical fiber to transmit the optical power generated to a launch vehicle via an actively cooled fiber spooler thereon. The optical power received by the launch vehicle is converted to another form of energy usable by the launch vehicle. The optical power is optically focused into a reaction chamber to impinge on a refractory target. A working fluid is regeneratively fed to a heat exchanger contained within the actively cooled fiber spooler. The working fluid is pre-heated within the heat exchanger and injected into the reaction chamber where the working fluid heats and expands. The exhaust is channeled through a rocket nozzle to produce thrust. In an alternative embodiment, the optical fiber expended during launch of a spacecraft is recovered. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/171167 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/00 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) E21B 47/135 (20200501) Optical Elements, Systems, or Apparatus G02B 6/3604 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4296 (20130101) G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4458 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/30 (20160201) H02J 50/90 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705539 | Pedersen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | Nissan North America, Inc. (Franklin, Tennessee); United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Liam Pedersen (San Francisco, California); Maarten Sierhuis (San Francisco, California); Hans Utz (Campbell, California); Mauro Della Penna (San Francisco, California); Terrence Fong (Moffett Field, California); Mark Allan (Campbell, California); Maria Bualat (San Jose, California); Eric Schafer (Kentfield, California) |
| ABSTRACT | Methods and systems for providing remote support and negotiating problem situations of autonomous operation of vehicles based on signal states and vehicle information are described. The disclosed technology receives state data for the vehicles by an apparatus such as a remote vehicle support apparatus. The state data indicates a respective current state for the vehicles. The vehicles are each assigned to respective remote vehicle support queues based on the respective state data. An indication that one of the vehicles is requesting remote support is received by the remote vehicle support apparatus. In response to a determination that a change in the state data indicates that autonomous operation of the one of the vehicles is operating outside of defined parameter values, the remote support is provided to the one of the vehicles through a communications link by transmitting instruction data to modify the autonomous operation of the one of the vehicles. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 16/348726 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0212 (20130101) G05D 1/0276 (20130101) G05D 1/0287 (20130101) G05D 1/0291 (20130101) Original (OR) Class G05D 1/0297 (20130101) G05D 2201/0213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10707966 | Velazco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jose E. Velazco (Pasadena, California) |
| ABSTRACT | An ultrafast omnidirectional wireless data transfer apparatus and system. The ultrafast omnidirectional wireless data transfer apparatus includes an array of laser diodes, an array of fast detectors, and a connector for connecting to a sensor, a computer, and/or a network. The array of laser diodes, and the array of fast detectors are housed in a multifaceted geometry in order to provide communication coverage in all directions. In one aspect, each laser in the array of laser diodes operates at different wavelengths. In another aspect, the ultrafast omnidirectional wireless data transfer apparatus includes field programmable gate arrays. In yet another aspect, the ultrafast omnidirectional wireless data transfer apparatus includes an array of collimators that are connected to an optical combiner. In yet another alternate aspect, an ultrafast omnidirectional wireless data transfer system includes several ultrafast omnidirectional wireless data transfer apparatuses which are optically coupled together and communicate in different wavelengths. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 16/394695 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/40 (20130101) Original (OR) Class H04B 10/1123 (20130101) H04B 10/1129 (20130101) H04B 10/1143 (20130101) H04B 10/1149 (20130101) H04B 10/2575 (20130101) H04B 2210/006 (20130101) Multiplex Communication H04J 14/02 (20130101) Wireless Communication Networks H04W 16/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10708794 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Friday, December 27, 2019 |
| APPL NO | 16/729178 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 15/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10703501 | Pruzan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Analytical Mechanics Associates, Inc. (Hampton, Virginia) |
| ASSIGNEE(S) | ANALYTICAL MECHANICS ASSOCIATES, INC. (Hampton, Virginia) |
| INVENTOR(S) | Daniel Allan Pruzan (Redwood City, California); Daniel Joseph Lesieutre (San Jose, California) |
| ABSTRACT | Systems, apparatus, and methods may control movement of an object through a fluid. The systems, apparatus, and methods may utilize a rotatable control unit including a pair of fins to generate a control force at least partially perpendicular to a direction of travel of the object through the fluid. One fin may be configured to generate a different amount of rolling moment than the other fin to provide rotational acceleration and energy production. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/461685 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/02 (20130101) Original (OR) Class B64D 39/04 (20130101) B64D 39/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703711 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ACELOT, INC. (Santa Barbara, California) |
| ASSIGNEE(S) | Acelot, Inc. (Santa Barbara, California) |
| INVENTOR(S) | Ambuj K. Singh (Santa Barbara, California); Christian A. Lang (Santa Barbara, California) |
| ABSTRACT | The present invention provides small molecule drugs and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of Aβ42 oligomers in a subject. It further provides a method of reducing formation of or disrupting Aβ42 oligomers in a subject, the method comprising the step of administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/350344 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/131 (20130101) A61K 31/135 (20130101) A61K 31/137 (20130101) Acyclic or Carbocyclic Compounds C07C 211/27 (20130101) C07C 211/28 (20130101) C07C 211/29 (20130101) C07C 217/60 (20130101) C07C 223/02 (20130101) C07C 233/43 (20130101) Original (OR) Class C07C 271/18 (20130101) Heterocyclic Compounds C07D 207/06 (20130101) C07D 295/15 (20130101) C07D 295/135 (20130101) C07D 319/18 (20130101) C07D 413/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10705063 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Fall River, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Ian Martin (Sharon, Massachusetts); Joseph G. Michels (New York, New York); Nathan Pallo (Somerville, Massachusetts); Peter Quigley (Duxbury, Massachusetts) |
| ABSTRACT | An apparatus for sampling landfill gas from a landfill flowing through a pipe. The apparatus may comprise: an enclosure configured to receive a section of the pipe; a gas sampling port in the section of the pipe; at least one sensor device disposed in a region of the enclosure, the at least one sensor being coupled to the section of the pipe through the gas sampling port; and thermal insulation positioned to retain heat from the section of the pipe in the region of the enclosure. A method of operating a landfill gas recovery system. The method may comprise: flowing gas from a well riser pipe through a sampling subsystem to a collection system; and heating a portion of the sampling subsystem with the gas flowing from the well riser pipe to the collection system. |
| FILED | Monday, March 20, 2017 |
| APPL NO | 15/464236 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) B09B 3/0016 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 36/00 (20130101) E21B 36/003 (20130101) E21B 47/06 (20130101) E21B 47/10 (20130101) E21B 47/065 (20130101) E21B 49/08 (20130101) E21B 2049/085 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2294 (20130101) G01N 33/004 (20130101) G01N 33/0006 (20130101) Original (OR) Class G01N 33/0036 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/20 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/20 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10703698 | Katzenellenbogen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | John A. Katzenellenbogen (Urbana, Illinois); Benita Katzenellenbogen (Urbana, Illinois); Sung Hoon Kim (Champaign, Illinois); Zeynep Madak-Erdogan (Champaign, Illinois); Philip Shaul (Richardson, Texas) |
| ABSTRACT | Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer. |
| FILED | Friday, January 06, 2017 |
| APPL NO | 16/067676 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 39/06 (20130101) C07C 39/12 (20130101) C07C 39/14 (20130101) C07C 39/17 (20130101) Original (OR) Class C07C 39/23 (20130101) C07C 39/42 (20130101) C07C 39/367 (20130101) C07C 43/196 (20130101) C07C 49/733 (20130101) C07C 49/755 (20130101) C07C 57/38 (20130101) C07C 235/34 (20130101) C07C 255/47 (20130101) C07C 2601/14 (20170501) C07C 2602/08 (20170501) C07C 2602/10 (20170501) C07C 2603/74 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704052 | Medina-Bolivar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arkansas State University Jonesboro (State University, Arkansas) |
| ASSIGNEE(S) | Arkansas State University Jonesboro (State University, Arkansas); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Luis Fabricio Medina-Bolivar (Jonesboro, Arkansas); Tianhong Yang (Jonesboro, Arkansas); Keithanne Mockaitis (Indianapolis, Indiana) |
| ABSTRACT | The process and system led to the identification of prenyltransferase genes from elicitor-treated peanut hairy roots. One of the prenyltransferases, AhR4DT-1 catalyzes a key reaction involved in the biosynthesis of prenylated stilbenoids, in which resveratrol is prenylated at its C-4 position to form arachidin-2, while another, AhR3′DT-1, was able to add the prenyl group to C-3′ of resveratrol. Each of these prenyltransferases has a high specificity for stilbenoid substrates, and their subcellular location in the plastid was confirmed by fluorescence microscopy. Structure analysis of the prenylated stilbenoids suggest that these two prenyltransferase activities represent the first committed steps in the biosynthesis of a large number of prenylated stilbenoids and their derivatives in peanut. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625450 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) C12N 15/8243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10702543 | Weisbart |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Richard H. Weisbart (Los Angeles, California) |
| ABSTRACT | Provided herein are conjugate molecules containing a substrate for a nucleoside transport pathway linked to an active agent, wherein the conjugate can be transported into a cell or into the nucleus of a cell via a cellular nucleoside transport pathway. Further provided are methods of delivering a conjugate molecule to a target cell expressing a nucleoside transport pathway, wherein the conjugate contains a substrate for the nucleoside transport pathway linked to an active agent. Also provided are methods for screening for conjugates that are transported by nucleoside transport pathways. Further provided are methods of treating a patient having a disease or disorder affecting tissues expressing nucleoside transport pathways, in which a conjugate containing an agent effective in treating the disorder is administered to the patient. Also provided are methods of treating a patient having an autoimmune disorder involving administering to the patient a compound that inhibits a nucleoside transport pathway. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 14/617494 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/6843 (20170801) Peptides C07K 16/44 (20130101) C07K 2317/77 (20130101) C07K 2317/82 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3513 (20130101) C12N 2320/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10703807 | Weisbart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. Weisbart (Sepulveda, California); Robert N. Nishimura (Sepulveda, California); James E. Hansen (Guilford, Connecticut) |
| ABSTRACT | The invention provides for a fusion protein comprising a 3E10 Fv joined to a Hsp-70, Hsp-27, Hsp-90 or GRP-78 or portion thereof, and optionally, the 3E10 Fv comprising an amino acid sequence AGIH at its amino terminus. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650752 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 10702735 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUTech Ventures (Lincoln, Nebraska); MADONNA REHABILITATION HOSPITAL (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska); Madonna Rehabilitation Hospital (Lincoln, Nebraska) |
| INVENTOR(S) | Carl A. Nelson (Lincoln, Nebraska); Cale J. Stolle (Lincoln, Nebraska); Judith M. Burnfield (Lincoln, Nebraska); Thad W. Buster (Gretna, Nebraska); Bernadette J. McCrory (Seward, Nebraska) |
| ABSTRACT | An elliptical system is disclosed having a crank assembly configured to be adjusted in length to accommodate users having varying gaits. In some embodiments, the crank assembly includes a crank and an axle connection bracket that is slidably adjustable with respect to the crank. For example, the crank assembly can include a crank link having a longitudinal body, where the longitudinal body is connected to the crank at one end and includes a longitudinal slot slidably coupled with the axle connection bracket. The axle connection bracket is configured to slide through a plurality of positions along the longitudinal body. In some embodiments, the crank assembly further includes a screw for adjusting the axle connection bracket with respect to the crank, where the screw can cause the axle connection bracket to slide through one or more positions of the plurality of positions when the screw is turned. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/560541 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/0059 (20151001) A63B 21/00069 (20130101) A63B 21/0085 (20130101) A63B 21/00181 (20130101) A63B 21/225 (20130101) A63B 22/001 (20130101) A63B 22/0015 (20130101) Original (OR) Class A63B 22/0664 (20130101) A63B 24/0062 (20130101) A63B 24/0087 (20130101) A63B 2022/067 (20130101) A63B 2024/009 (20130101) A63B 2208/12 (20130101) A63B 2225/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10706144 | Moritz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BlueRISC, Inc. (Amherst, Massachusetts) |
| ASSIGNEE(S) | BlueRISC, Inc. (Amherst, Massachusetts) |
| INVENTOR(S) | Csaba Andras Moritz (Amherst, Massachusetts); Kristopher Carver (Belchertown, Massachusetts); Santosh Khasanvis (Amherst, Massachusetts); Jeffry Gummeson (Hadley, Massachusetts) |
| ABSTRACT | An example process that is performed by one or more processing devices uses one or more system states to detect cyber-attacks. The example process includes the following operations: generating a first graph that models states based on information obtained from an electronic device; and performing a correlation of the first graph with one or more second graphs to detect a possibility of a cyber-attack against the electronic device. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261326 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/55 (20130101) Original (OR) Class G06F 21/56 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 10704993 | Barnhart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elliott Barnhart (Clancy, Montana); Robert Hyatt (Butte, Montana); Mathew Fields (Bozeman, Montana); Alfred B Cunningham (Bozeman, Montana) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Department of the Interior (Washington, District of Columbia) |
| INVENTOR(S) | Elliott Barnhart (Clancy, Montana); Robert Hyatt (Butte, Montana); Mathew Fields (Bozeman, Montana); Alfred B Cunningham (Bozeman, Montana) |
| ABSTRACT | A Sampler and process for collecting, growing, inoculating and evaluating microbes in-situ. The Sampler may be loaded with an active or inert media to assist with the collection of microbes. It is closed and lowered to a desired depth. Sampler is opened to initiate sampling. Materials are added to the sampler to stimulate growth or change the environment. To collect and grow in situ microbes, the sampler is left open for a period of time, a trigger closes and seals the sampler capturing contents specific to that location. The sampler is lifted preserving the in-situ conditions from the collection location. The contents of the sampler can be interrogated through sealed ports at the field site or at a remote location. The sampler can also be utilized as a biologic reactor allowing researchers to connect laboratory equipment to analyze, modify, or cultivate the collected sample. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615794 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/64 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 49/082 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/12 (20130101) G01N 1/18 (20130101) Original (OR) Class G01N 1/2294 (20130101) G01N 2001/1031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10704052 | Medina-Bolivar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arkansas State University Jonesboro (State University, Arkansas) |
| ASSIGNEE(S) | Arkansas State University Jonesboro (State University, Arkansas); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Luis Fabricio Medina-Bolivar (Jonesboro, Arkansas); Tianhong Yang (Jonesboro, Arkansas); Keithanne Mockaitis (Indianapolis, Indiana) |
| ABSTRACT | The process and system led to the identification of prenyltransferase genes from elicitor-treated peanut hairy roots. One of the prenyltransferases, AhR4DT-1 catalyzes a key reaction involved in the biosynthesis of prenylated stilbenoids, in which resveratrol is prenylated at its C-4 position to form arachidin-2, while another, AhR3′DT-1, was able to add the prenyl group to C-3′ of resveratrol. Each of these prenyltransferases has a high specificity for stilbenoid substrates, and their subcellular location in the plastid was confirmed by fluorescence microscopy. Structure analysis of the prenylated stilbenoids suggest that these two prenyltransferase activities represent the first committed steps in the biosynthesis of a large number of prenylated stilbenoids and their derivatives in peanut. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 15/625450 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) C12N 15/8243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10703981 | Urynowicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Michael A. Urynowicz (Fort Collins, Colorado); Zaixing Huang (Laramie, Wyoming) |
| ABSTRACT | Use of chemical pretreatment agents on the subsequent enzymatic conversion of coal is described. As an example, fungal manganese peroxidase (MnP) produced by the agaric white-rot fungus Bjerkandera adusta, where the enzyme MnP has little effect on the untreated coal controls, was investigated. The nature of pretreatment agents and their applied concentrations were found to have significant impact on subsequent enzymatic conversion of coal. Four agents were investigated: HNO3, catalyzed H2O2, KMnO4, and NaOH. Hydrogen peroxide was found to generate the greatest quantity of total organic carbon from the coal samples employed. Combined chemical and enzymatic treatment of coal is appropriate for enhanced depolymerisation of coal and coal-derived constituents and results in chemically heterogeneous and complex liquefaction products like humic and fulvic acids, which will have important ramifications in the generation of liquid and gaseous fuels from coals as nonpetroleum-derived fuel alternatives. |
| FILED | Thursday, May 23, 2013 |
| APPL NO | 13/901470 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/00 (20130101) C10G 1/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10704416 | Ha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Joon Ha (Glastonbury, Connecticut); John P. Lucashu (Durham, Connecticut) |
| ABSTRACT | A conformal heat shield for a gas turbine engine may comprise a first section including a first arcuate segment and a second arcuate segment circumferentially adjacent to the first arcuate segment. The first arcuate segment and the second arcuate segment may each comprise a distal metal layer including a plurality of loops extending radially outward from the distal metal layer. A proximal metal layer may be located radially inward of the distal metal layer. An insulating material may be located between the distal metal layer and the proximal metal layer. A first strap may be located through the loops. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/034813 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/145 (20130101) Original (OR) Class F01D 25/243 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 07, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200707.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page