FedInvent™ Patents

Patent Details for Tuesday, July 28, 2020 

This page was updated on Monday, March 27, 2023 at 06:08 AM GMT

Department of Health and Human Services (HHS) 

US 10722116 Rege et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Vasoptic Medical Inc. (Baltimore, Maryland)
ASSIGNEE(S) Vasoptic Medical Inc. (Baltimore, Maryland)
INVENTOR(S) Abhishek Rege (Baltimore, Maryland);  M. Jason Brooke (University Park, Maryland)
ABSTRACT Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging of the back and/or front of the eye using multiple illumination modalities, which permits the collection of one or more of reflectance, spectroscopic, fluorescence, and laser speckle contrast images.
FILED Monday, October 17, 2016
APPL NO 15/295887
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/0008 (20130101)
A61B 3/12 (20130101)
A61B 3/14 (20130101) Original (OR) Class
A61B 3/18 (20130101)
A61B 3/0025 (20130101)
A61B 3/0033 (20130101)
A61B 3/0041 (20130101)
A61B 3/0075 (20130101)
A61B 3/0083 (20130101)
A61B 3/0091 (20130101)
A61B 3/152 (20130101)
A61B 3/1208 (20130101)
A61B 3/1233 (20130101)
A61B 3/1241 (20130101)
A61B 5/0013 (20130101)
A61B 5/02007 (20130101)
A61B 5/6803 (20130101)
A61B 2560/0475 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722137 Fielden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Samuel Fielden (Charlottesville, Virginia);  Li Zhao (Charlottesville, Virginia);  Wilson Miller (Charlottesville, Virginia);  Xue Feng (Charlottesville, Virginia);  Max Wintermark (Charlottesville, Virginia);  Kim Butts Pauly (Charlottesville, Virginia);  Craig H. Meyer (Charlottesville, Virginia)
ABSTRACT Aspects of the present disclosure relate to magnetic resonance thermometry. In one embodiment, a method includes acquiring undersampled magnetic resonance data associated with an area of interest of a subject receiving focused ultrasound treatment, and reconstructing images corresponding to the area of interest based on the acquired magnetic resonance data, where the reconstructing uses Kalman filtering.
FILED Thursday, April 02, 2015
APPL NO 14/677915
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/015 (20130101)
A61B 5/055 (20130101) Original (OR) Class
A61B 5/725 (20130101)
A61B 2018/00791 (20130101)
A61B 2090/374 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722138 Blank et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Technion Research and Development Foundation Limited (Haifa, Israel)
ASSIGNEE(S) Technion Research and Development Foundation Limited (Haifa, Israel)
INVENTOR(S) Aharon Blank (Kfar-Vradim, Israel);  Periannan Kuppusamy (Hanover, New Hampshire);  Ahmad Rizwan (Columbus, Ohio)
ABSTRACT Electron paramagnetic resonance (EPR) systems and methods for transcutaneous oxygen monitoring (TCOM) and subcutaneous oxygen monitoring (SCOM) are provided herein. Optionally, the EPR systems provided herein can be portable and/or handheld to facilitate EPR oximetry in clinical environments.
FILED Thursday, June 11, 2015
APPL NO 15/318073
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/748 (20130101)
A61B 5/6833 (20130101)
A61B 5/14503 (20130101)
A61B 5/14542 (20130101)
A61B 2560/0406 (20130101)
A61B 2560/0418 (20130101)
A61B 2562/046 (20130101)
A61B 2562/0223 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/60 (20130101)
G01R 33/285 (20130101)
G01R 33/343 (20130101)
G01R 33/383 (20130101)
G01R 33/448 (20130101)
G01R 33/3808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722190 Badal-Soler
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Andreu Badal-Soler (Bethesda, Maryland)
ABSTRACT Disclosed herein are adaptive filters, radiographic systems, and methods for controlling the radiation exposure of a target object during a radiographic imaging procedure. An adaptive filter can comprise first and second dynamic collimators that block or attenuate radiation that is incident upon the collimators, but allow radiation to pass between the collimators to reach the target object and radiation detector. The collimators can move relative to each other during a radiation emission such that the motion of the collimators allows different amounts of radiation from the radiation source to pass between the two collimators to each portion of the target object during the radiation emission. The amounts of radiation allowed to reach each portion of the target object can be determined based on a thickness of each portion of the target object.
FILED Monday, August 08, 2016
APPL NO 15/751119
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/06 (20130101) Original (OR) Class
A61B 6/032 (20130101)
A61B 6/502 (20130101)
A61B 6/544 (20130101)
A61B 6/582 (20130101)
A61B 6/4035 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/10 (20130101)
G21K 1/025 (20130101)
G21K 1/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722221 Kalloo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Anthony N. Kalloo (Baltimore, Maryland);  David H. Gracias (Baltimore, Maryland);  Florin M. Selaru (Catonsville, Maryland);  Evin Gultepe (Baltimore, Maryland);  Mouen A. Khashab (Towson, Maryland)
ABSTRACT The present invention utilizes tetherless microtools to biopsy tissue. The invention provides a device and method for deployment and retrieval of tetherless microtools. The size of the microtools ensures that tissue damage at a site targeted for biopsy is negligible. As such, large numbers of microtools may be deployed ensuring that a true statistical sampling of biologic tissue is performed.
FILED Monday, July 31, 2017
APPL NO 15/665066
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/02 (20130101)
A61B 10/04 (20130101) Original (OR) Class
A61B 2017/00345 (20130101)
A61B 2017/00876 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722250 Tasci et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S) Colorado School of Mines (Golden, Colorado)
INVENTOR(S) Tonguc Onur Tasci (Golden, Colorado);  Keith B. Neeves (Denver, Colorado);  David W. M. Marr (Golden, Colorado)
ABSTRACT The invention relates to a magnetic-field driven colloidal microbot that employs wall-based propulsion, method of forming the microbot and a method of using the microbot. The microbot can be formed in situ with the use of magnetic fields, and the magnetic fields can be used to translate the microbot to a specified location in a patient. The microbot does not depend on “swimming” or flow currents within a patient to move, but instead can propel itself along a surface using a magnetic field. Once the magnetic field is removed, the microbot disassembles into colloidal particles.
FILED Monday, March 14, 2016
APPL NO 15/069681
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/22 (20130101) Original (OR) Class
A61B 17/3207 (20130101)
A61B 34/72 (20160201)
A61B 34/73 (20160201)
A61B 2017/00345 (20130101)
A61B 2017/22082 (20130101)
A61B 2034/303 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722468 Mathiowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Brown University (Providence, Rhode Island);  Therapyx, Inc. (Buffalo, New York)
ASSIGNEE(S) BROWN UNIVERSITY (Providence, Rhode Island);  THERAPYX, INC. (Buffalo, New York)
INVENTOR(S) Edith Mathiowitz (Brookline, Massachusetts);  Stacia Furtado (Pawcatuck, Connecticut);  Nejat Egilmez (Louisville, Kentucky);  Thomas Conway (Hamburg, New York)
ABSTRACT Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate or nanoparticulate bioactive agents. The carriers are especially useful for stabilizing bioactive macromolecules, such as proteins.
FILED Friday, August 14, 2015
APPL NO 15/503891
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101) Original (OR) Class
A61K 9/19 (20130101)
A61K 9/1635 (20130101)
A61K 9/1641 (20130101)
A61K 9/1647 (20130101)
A61K 9/2004 (20130101)
A61K 38/17 (20130101)
A61K 38/20 (20130101)
A61K 38/28 (20130101)
A61K 38/191 (20130101)
A61K 38/193 (20130101)
A61K 38/208 (20130101)
A61K 38/1841 (20130101)
A61K 38/1858 (20130101)
A61K 38/1866 (20130101)
A61K 38/2066 (20130101)
A61K 39/00 (20130101)
A61K 2039/555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722515 Webb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) SRI INTERNATIONAL (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Thomas R. Webb (Mountain View, California);  Jaehyeon Park (Sunnyvale, California);  Chandraiah Lagisetti (Cupertino, California)
ABSTRACT The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, September 29, 2017
APPL NO 16/334229
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101) Original (OR) Class
A61K 31/437 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 473/16 (20130101)
C07D 473/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722517 Quail et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Daniela Francis Quail (Montreal, Canada);  Johanna Alexandra Joyce (Lausanne, Switzerland);  Robert Lyle Bowman (New York, New York)
ABSTRACT In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.
FILED Monday, May 09, 2016
APPL NO 15/572456
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/416 (20130101)
A61K 31/423 (20130101)
A61K 31/426 (20130101)
A61K 31/428 (20130101)
A61K 31/437 (20130101)
A61K 31/496 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/4184 (20130101)
A61K 31/4406 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722523 Karin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael Karin (La Jolla, California);  Shabnam Shalapour (San Diego, California)
ABSTRACT The invention provides a method for treating cancer in a subject in need thereof, wherein said subject comprises cancer tissue that ‘contains epithelial cancer cells and immunosuppressive 8 cells, and wherein said method comprises administering to said subject a therapeutically effective amount of a) one or more first composition that pauses—immunogenic eel’ death and/or of said epithelial cancer cells, and b) one or more second composition that reduces one or both of the number and function of said immunosuppressive B cells in said cancer.
FILED Thursday, March 17, 2016
APPL NO 15/558439
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/136 (20130101)
A61K 31/136 (20130101)
A61K 31/555 (20130101) Original (OR) Class
A61K 31/555 (20130101)
A61K 31/675 (20130101)
A61K 31/675 (20130101)
A61K 38/05 (20130101)
A61K 38/05 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Peptides
C07K 16/2827 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722529 Rappaport et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Jay F. Rappaport (Wynnewood, Pennsylvania);  Xuebin Qin (Westwood, Massachusetts);  Stephani Velasquez (Philadelphia, Pennsylvania)
ABSTRACT The present invention encompasses compositions and methods for regulating the kynurenine to tryptophan ratio, NAD+ level and CD16 expression for the treatment diseases.
FILED Friday, December 02, 2016
APPL NO 15/780664
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/353 (20130101)
A61K 31/706 (20130101) Original (OR) Class
A61K 31/706 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722537 Masopust, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) David B. Masopust, Jr. (Minneapolis, Minnesota);  Vaiva D. Vezys (Minneapolis, Minnesota)
ABSTRACT Provided herein are methods of treating cancer by activating resident memory T cells using one or more antigenic peptides.
FILED Monday, November 07, 2016
APPL NO 15/774163
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 39/395 (20130101)
A61K 39/39558 (20130101)
A61K 48/0058 (20130101)
A61K 48/0066 (20130101)
A61K 2039/585 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 2710/10032 (20130101)
C12N 2760/10034 (20130101)
C12N 2760/20234 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/392 (20180101)
Y02A 50/466 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722567 King et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) GlobeImmune, Inc. (Louisville, Colorado);  Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S) GlobeImmune, Inc. (Louisville, Colorado);  Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Thomas H. King (Denver, Colorado);  Zhimin Guo (Superior, Colorado);  Ian M. Orme (Fort Collins, Colorado)
ABSTRACT Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
FILED Monday, February 04, 2019
APPL NO 16/266224
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 39/04 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 2039/521 (20130101)
A61K 2039/523 (20130101)

Peptides
C07K 14/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722568 Bakaletz
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio)
ASSIGNEE(S) RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio)
INVENTOR(S) Lauren O. Bakaletz (Hilliard, Ohio)
ABSTRACT Provided are topical delivery systems and methods for treating and/or preventing a disease or disorder in a subject, or for eliciting an immune response in a subject including applying, to at least a portion of the subject's post-auricular region, a topical delivery system including a therapeutically effective amount of a topical pharmaceutical composition comprising at least one active agent and a pharmaceutically acceptable carrier and/or adjuvant. The topical pharmaceutical composition can include a topical immunogenic composition. The topical delivery system can further include a flexible substrate in communication with the topical immunogenic composition. The subject can be a pediatric subject.
FILED Tuesday, November 28, 2017
APPL NO 15/824387
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/7084 (20130101)
A61K 39/102 (20130101) Original (OR) Class
A61K 39/385 (20130101)
A61K 2039/54 (20130101)
A61K 2039/60 (20130101)
A61K 2039/541 (20130101)
A61K 2039/545 (20130101)
A61K 2039/6068 (20130101)
A61K 2039/55544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722569 Watnick
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Paula I. Watnick (Waban, Massachusetts)
ABSTRACT Some aspects of this disclosure provide engineered exopolysaccharide-associated proteins, engineered bacteria expressing such proteins, and engineered biofilms comprising such proteins. Some aspects of this disclosure provide methods for engineering exopolysaccharide-associated proteins, and for the generation of engineered bacteria and biofilms expressing or comprising such proteins. Some aspects of this disclosure provide compositions and methods useful for the generation of vaccines and the vaccination of subjects, for delivering molecules of interest to a target site, for example, a surface, for purification of molecules of interest, for example, from bioreactors comprising engineered bacteria as provided herein, and for bioremediation applications, such as the cleanup of environmental pollutants.
FILED Wednesday, July 03, 2013
APPL NO 14/411647
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/47 (20130101)
A61K 39/02 (20130101)
A61K 39/107 (20130101) Original (OR) Class
A61K 47/6901 (20170801)
A61K 2039/52 (20130101)
A61K 2039/627 (20130101)
A61K 2039/6006 (20130101)
A61K 2039/6087 (20130101)
A61K 2039/55594 (20130101)

Enzymes
C12Y 302/01014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722577 Rotolo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sloan Kettering Institute for Cancer Research (New York, New York)
ASSIGNEE(S) Sloan Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Jimmy Andrew Rotolo (Port Washington, New York);  Richard N. Kolesnick (New York, New York)
ABSTRACT It has been discovered that administering therapeutically effective amounts of an antibiotic that kills Gram-negative bacteria, together with an anti-ceramide antibody or anti-ceramide mimetic, treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTL)-induced killing and/or by damage to endothelial microvasculature, including Radiation GI syndrome, GvHD disease, inflammatory diseases and autoimmune diseases.
FILED Tuesday, May 28, 2013
APPL NO 14/402875
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 39/39533 (20130101) Original (OR) Class
A61K 39/39541 (20130101)
A61K 39/39541 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/18 (20130101)
C07K 16/44 (20130101)
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722580 Sokurenko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S) Evgeni V. Sokurenko (Seattle, Washington);  Dagmara Kisiela (Seattle, Washington);  Wendy Evelyn Thomas (Seattle, Washington);  Veronika L. Tchesnokova (Seattle, Washington)
ABSTRACT Methods and antibody compositions that displace mannose from the binding pocket of fimbrial adhesin FimH of enterobacteria, including uropathogenic E. coli, Klebsiella oxytoca, or Klebsiella pneumoniae, can be used to disrupt or prevent the attachment of a single layer of bacteria to a mannose-coated surface, or to disrupt or prevent the formation of a multilayer biofilm. The antibody compositions of the invention can thus be used in methods to inhibit, prevent, or reverse the colonization of a surface with enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, to inhibit or prevent infection of a cell by enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, such as, for example, uropathogenic E. coli, to treat a bacterial infection in subject in need thereof and to treat or prevent inflammatory bowel disease (IBD), among other uses.
FILED Friday, May 13, 2016
APPL NO 15/573748
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101)
A61K 39/40 (20130101) Original (OR) Class
A61K 2039/52 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/04 (20180101)
A61P 13/10 (20180101)
A61P 31/04 (20180101)

Peptides
C07K 14/245 (20130101)
C07K 16/1232 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722598 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) James M. Wilson (Philadelphia, Pennsylvania);  Guangping Gao (Westborough, Massachusetts);  Mauricio R. Alvira (Philadelphia, Pennsylvania);  Luc H. Vandenberghe (Weston, Massachusetts)
ABSTRACT Sequences of novel adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the invention is also provided.
FILED Tuesday, October 02, 2018
APPL NO 16/149216
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101) Original (OR) Class

Peptides
C07K 14/005 (20130101)
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/644 (20130101)
C12N 15/86 (20130101)
C12N 2750/14121 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14142 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14151 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 304/21022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722600 Cadwell
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Kenneth Cadwell (Forest Hills, New York)
ABSTRACT The present invention relates to the use of NS1/2 region of murine norovirus MNV or a corresponding region from a member of the Caliciviridae family or a protein encoded by any one of those regions, for treating dysbiosis, immune system dysregulation and various disorders, as well as for enhancing mucosal integrity and stimulating IFN-induced genes.
FILED Friday, June 16, 2017
APPL NO 15/625934
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/005 (20130101) Original (OR) Class

Peptides
C07K 14/005 (20130101)
C07K 14/08 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2770/16043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722615 Misra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Sanjay Misra (Rochester, Minnesota);  Allan B. Dietz (Chatfield, Minnesota)
ABSTRACT This document provides methods and materials involved in reducing venous neointimal hyperplasia (VNH) of an arteriovenous fistula (AVF) or graft. For example, methods and materials for using stem cells (e.g., mesenchymal stem cells), extracellular matrix material, or a combination of stem cells and extracellular matrix material to reduce VNH of AVFs or grafts are provided.
FILED Wednesday, May 01, 2019
APPL NO 16/400962
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 35/28 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/507 (20130101)
A61L 27/3633 (20130101)
A61L 27/3834 (20130101)
A61L 31/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722784 Burdea et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) BRIGHT CLOUD INTERNATIONAL CORP. (Highland Park, New Jersey)
ASSIGNEE(S) Bright Cloud International Corporation (Highland Park, New Jersey)
INVENTOR(S) Grigore Cristian Burdea (Highland Park, New Jersey);  Doru Tadeusz Roll (Long Beach, New York);  Nam-Hun Kim (Paramus, New Jersey);  Kevin Abraham Polistico (Princeton, New Jersey);  Ashwin Kadaru (Old Bridge, New Jersey)
ABSTRACT A system provides bi-manual game-based integrative therapy combining cognitive training with mild upper body physical exercising during game play. The system includes a pair of interfaces tracking a user's arms in 3D and detect trigger pressing. Custom therapeutic game controllers that detect grasping force, finger extension, 3D hand position, skin temperature and pulse may be used. Using one of these interfaces the patient plays a series of custom games displayed on a laptop, medical grade workstation, or other computer platform. The whole therapeutic system may be integrated on a medical cart, so to make the system mobile and easier to place in a clinical setting. Games were designed to improve motor control, shoulder strength, finger and arm range of motion, task sequencing, focusing, decision making (executive function), short term and long term visual/auditory memory, and were progressed in difficulty over 6 to 8 weeks of therapy. This therapy reduces depression.
FILED Sunday, August 06, 2017
APPL NO 15/669952
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02055 (20130101)
A61B 5/02438 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/00 (20130101)

Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for
A63F 13/06 (20130101)
A63F 13/42 (20140902)
A63F 13/85 (20140902)
A63F 13/211 (20140902) Original (OR) Class
A63F 13/218 (20140902)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/30 (20180101)
G16H 40/63 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722889 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ABSTRACT A microfluidic apparatus, systems and methods for microfluidic crystallization based on gradient mixing. In one embodiment, the apparatus includes (a) a first layer, (b) a plurality of first channels and a plurality of vacuum chambers both arranged in the first layer, where the plurality of vacuum chambers are each coupled to at least one of the first channels, (c) a membrane having first and second surfaces, where the first surface of the membrane is coupled to the first layer, (d) a second layer coupled to the second surface of the membrane, (e) a plurality of wells and a plurality of second channels both arranged in the second layer, where the wells are each coupled to at least one of the plurality of second channels and (f) a plurality of barrier walls each disposed in the plurality of second channels and arranged opposite to one of the plurality of vacuum chambers.
FILED Monday, December 31, 2018
APPL NO 16/237158
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0652 (20130101)
B01L 2300/16 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0848 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0887 (20130101)
B01L 2300/0896 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0424 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723708 Remiszewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) FORGE Life Science, LLC (Doylestown, Pennsylvania)
ASSIGNEE(S) Evrys Bio, LLC (Doylestown, Pennsylvania)
INVENTOR(S) Stacy Remiszewski (Doylestown, Pennsylvania);  Emre Koyuncu (Doylestown, Pennsylvania);  Qun Sun (Princeton, Pennsylvania);  Lillian Chiang (Princeton, Pennsylvania)
ABSTRACT This document relates to compounds useful as agents for preventing or treating human cytomegalovirus (HCMV) infections.
FILED Monday, November 09, 2015
APPL NO 15/525401
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/522 (20130101)
A61K 31/4035 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/12 (20180101)
A61P 31/20 (20180101)

Acyclic or Carbocyclic Compounds
C07C 217/62 (20130101)
C07C 235/38 (20130101)

Heterocyclic Compounds
C07D 209/04 (20130101)
C07D 209/08 (20130101)
C07D 215/40 (20130101)
C07D 241/44 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723717 Crew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Arvinas, Inc. (New Haven, Connecticut);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) ARVINAS OPERATIONS, INC. (New Haven, Connecticut);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Andrew P. Crew (Guilford, Connecticut);  Keith R. Hornberger (Southbury, Connecticut);  Jing Wang (Milford, Connecticut);  Hanqing Dong (Madison, Connecticut);  Yimin Qian (Plainsboro, New Jersey);  Craig M. Crews (New Haven, Connecticut);  Saul Jaime-Figueroa (Morris Plains, New Jersey)
ABSTRACT The present disclosure relates to bifunctional compounds, which find utility as modulators of Rapidly Accelerated Fibrosarcoma (RAF, such as c-RAF, A-RAF and/or B-RAF; the target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hippel-Lindau, cereblon, Inhibitors of Apotosis Proteins or mouse double-minute homolog 2 ligand which binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein RAF, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein, or the constitutive activation of the target protein, are treated or prevented with compounds and compositions of the present disclosure.
FILED Friday, December 22, 2017
APPL NO 15/853166
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/437 (20130101)
A61K 31/4188 (20130101)
A61K 31/4439 (20130101)
A61K 31/4545 (20130101)
A61K 45/06 (20130101)
A61K 47/55 (20170801)
A61K 47/555 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 25/00 (20180101)
A61P 35/00 (20180101)
A61P 43/00 (20180101)

Heterocyclic Compounds
C07D 401/04 (20130101)
C07D 401/14 (20130101) Original (OR) Class
C07D 417/14 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723726 Barbosa
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GB006, INC. (San Diego, California)
ASSIGNEE(S) GB006, INC. (San Diego, California)
INVENTOR(S) Antonio J. Barbosa (Ave Maria, Florida)
ABSTRACT The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating 2 integrin-mediated diseases and conditions using the salts and crystalline forms.
FILED Friday, June 10, 2016
APPL NO 15/735560
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Acyclic or Carbocyclic Compounds
C07C 215/08 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723737 Hertz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Mitokinin LLC (New York, New York)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  MITOKININ LLC (New York, New York)
INVENTOR(S) Nicholas T. Hertz (San Francisco, California);  Kevan M. Shokat (San Francisco, California);  Robert DeVita (Westfield, New Jersey)
ABSTRACT Disclosed herein inter alia are compositions and methods useful in the treatment neurodegenerative diseases and cardiomyopathy, and for modulating the activity of PINK1.
FILED Tuesday, February 21, 2017
APPL NO 15/438496
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 473/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723744 Alexander et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Aphios Corporation (Woburn, Massachusetts);  For the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)
INVENTOR(S) Jonathan Steven Alexander (Shreveport, Louisiana);  April C. Carpenter (Cincinnati, Ohio);  Trevor Percival Castor (Arlington, Massachusetts)
ABSTRACT Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and pharmaceutically acceptable salts thereof.
FILED Friday, June 08, 2018
APPL NO 16/004039
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/365 (20130101)
A61K 47/14 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/06 (20180101)

Heterocyclic Compounds
C07D 493/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723753 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Nathanael Gray (Boston, Massachusetts);  Sang Min Lim (San Diego, California);  Hwan Geun Choi (Chestnut Hill, Massachusetts);  Kenneth Dale Westover (Southlake, Texas);  Matthew Meyerson (Concord, Massachusetts)
ABSTRACT Described herein are compounds of Formulae (I)-(II), and pharmaceutically acceptable salts, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases such as cancers (e.g., lung cancer, large bowel cancer, pancreas cancer, biliary tract cancer, or endometrial cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases in a subject.
FILED Thursday, March 13, 2014
APPL NO 14/775162
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/708 (20130101)
A61K 31/708 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/65616 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/16 (20130101) Original (OR) Class
C07H 19/20 (20130101)
C07H 19/167 (20130101)
C07H 19/207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723764 Wang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Guangshun Wang (Omaha, Nebraska)
ABSTRACT Anti-microbial peptides and methods of use are provided.
FILED Thursday, April 30, 2015
APPL NO 14/700908
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723768 Zhong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Li Zhong (Gainesville, Florida);  Sergei Zolotukhin (Gainesville, Florida);  Lakshmanan Govindasamy (Gainesville, Florida);  Mavis Agbandje-McKenna (Gainesville, Florida);  Arun Srivastava (Gainesville, Florida)
ABSTRACT Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors.
FILED Friday, August 18, 2017
APPL NO 15/680668
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101)
A61K 39/0011 (20130101)
A61K 48/005 (20130101)
A61K 48/0008 (20130101)
A61K 48/0091 (20130101)
A61K 2039/5158 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/8645 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14132 (20130101)
C12N 2750/14142 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2750/14171 (20130101)
C12N 2810/6027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723771 Hang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Howard Hang (New York, New York);  Kavita Rangan (New York, New York);  Daniel Mucida (New York, New York);  Virginia Pedicord (New York, New York)
ABSTRACT Provided are compositions and methods based in part on the discovery that Enterococcus faecium heterologous secreted antigen A (SagA)-produced peptidoglycan fragments are protective against enteric bacterial infections. Modified bacteria that are engineered to express heterologous SagA are provided, and are included a nutraceutical, pharmaceutical, and probiotic formulations, and as components of food products, including dairy products. The modified bacteria include modified Lactobacillus bacteria that express heterologous SagA. The disclosure includes a method that involves introducing into an individual modified bacteria of that express and secrete heterologous SagA. The disclosure provides isolated peptidoglycan fragment preparations made by a exposing a composition that contains peptidoglycan to an isolated or recombinant SagA, or to modified bacteria expressing a heterologous SagA, allowing SagA to generate the peptidoglycan fragments, and separating the peptidoglycan fragments from the composition to obtain the isolated peptidoglycan fragments or a preparation that contains them.
FILED Friday, April 22, 2016
APPL NO 15/568726
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof
A23C 9/1203 (20130101)
A23C 9/1234 (20130101)

Fodder
A23K 10/18 (20160501)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 33/135 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation
A23Y 2220/67 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/744 (20130101)
A61K 2035/11 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 14/315 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723778 Pioszak
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Augen A. Pioszak (Edmond, Oklahoma)
ABSTRACT Variant peptides of calcitonin gene-related peptide alpha (αCGRP), calcitonin gene-related peptide beta (βCGRP), and adrenomedullin (AM) are disclosed, wherein the variant peptides have high binding affinity and agonistic or antagonistic activity for at least one receptor complex of CLR:RAMP1, CLR:RAMP2, and CLR:RAMP3. Also disclosed are methods of use of the variant peptides in therapeutic treatments.
FILED Friday, October 04, 2019
APPL NO 16/593336
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/575 (20130101)
C07K 14/585 (20130101) Original (OR) Class
C07K 14/57527 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723779 Gellman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Samuel H. Gellman (Madison, Wisconsin);  Lisa M. Johnson (Glendale, California);  Alan Attie (Madison, Wisconsin);  Mark P. Keller (McFarland, Wisconsin);  Alan Saghatelian (Cambridge, Massachusetts)
ABSTRACT Described herein are peptide analogs of glucagon-like peptide 1 (GLP-1) that retain agonist activity, but are more resistant to proteolytic degradation than native GLP-1. In the analogs, at least one α-amino acid found in the native GLP-1 is replaced with a β-amino acid residue, which may or may not be cyclically constrained. Pharmaceutical compositions containing the analogs are described, as are methods to treat diabetes, and methods to make proteolytically resistant GLP-1 analogs.
FILED Thursday, July 13, 2017
APPL NO 15/648937
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/605 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723787 Perron et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) GENEURO SA (Plan-les-Ouates, Switzerland);  THE UNITED STATES OF AMERICA, as represented by the secretary, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) GENEURO SA (Plan-les-Oates, Switzerland);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S) Hervé Perron (Saint Genis les Ollieres, France);  Julie Medina (Lentilly, Switzerland);  Avindra Nath (Silver Spring, Maryland);  Joseph Perry Steiner (Mounty Airy, Maryland);  Wenxue Li (Rockville, Maryland);  Myound-Hwa Lee (Silver Spring, Maryland)
ABSTRACT The present invention relates to a novel antibody against HERV-K envelope that targets a conserved region not affected by glycosylation or by native conformation, and its use in diagnostics and/or in therapy.
FILED Friday, January 19, 2018
APPL NO 16/478576
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/15 (20130101)
A61K 39/42 (20130101)
A61K 39/245 (20130101)
A61K 39/395 (20130101)
A61K 2039/60 (20130101)
A61K 2039/505 (20130101)
A61K 2039/525 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6075 (20130101)
A61K 2121/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)
A61P 25/00 (20180101)
A61P 25/02 (20180101)
A61P 25/14 (20180101)
A61P 25/28 (20180101)
A61P 31/00 (20180101)
A61P 31/12 (20180101)
A61P 31/14 (20180101)
A61P 31/20 (20180101)
A61P 31/22 (20180101)

Peptides
C07K 16/1036 (20130101) Original (OR) Class
C07K 2317/00 (20130101)
C07K 2317/10 (20130101)
C07K 2317/34 (20130101)
C07K 2317/50 (20130101)
C07K 2317/62 (20130101)
C07K 2317/64 (20130101)
C07K 2317/66 (20130101)
C07K 2317/70 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)
C07K 2317/624 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2320/00 (20130101)
C12N 2320/50 (20130101)
C12N 2710/00011 (20130101)
C12N 2710/00022 (20130101)
C12N 2710/16011 (20130101)
C12N 2710/16122 (20130101)
C12N 2740/10011 (20130101)
C12N 2740/10022 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/563 (20130101)
G01N 33/569 (20130101)
G01N 33/6896 (20130101)
G01N 2333/15 (20130101)
G01N 2469/00 (20130101)
G01N 2469/10 (20130101)
G01N 2800/00 (20130101)
G01N 2800/28 (20130101)
G01N 2800/52 (20130101)
G01N 2800/56 (20130101)
G01N 2800/285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723790 McAllister et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
INVENTOR(S) Janette M. McAllister (Hummelstown, Pennsylvania);  Jerome F. Strauss (Richmond, Virginia);  Neil D. Christensen (Harrisburg, Pennsylvania)
ABSTRACT Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.
FILED Tuesday, November 27, 2018
APPL NO 16/201360
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2333/4706 (20130101)
G01N 2800/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723794 Kiaris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Hippokratis Kiaris (Irmo, South Carolina);  Eleni Farmaki (Columbia, South Carolina);  Ioulia Chatzistamou (Irmo, South Carolina);  Vimala Kaza (Lexington, South Carolina)
ABSTRACT Anti-CCL8 antibodies and antigen binding fragments thereof are described. Antibodies and fragments thereof can be used for prevention of migration of breast cancer cells. Methods include delivery of an anti-CCL8 antibody or an antigen binding fragment thereof to an area including the breast cancer cells, e.g., delivery to a subject in need thereof in an effective amount.
FILED Monday, April 01, 2019
APPL NO 16/371386
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 16/24 (20130101) Original (OR) Class
C07K 16/3015 (20130101)
C07K 2317/76 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723803 Weiskopf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Kipp Andrew Weiskopf (Brookline, Massachusetts);  Kim J. Hasenkrug (Victor, Montana);  Cheryl A. Stoddart (Pacifica, California);  Joseph McCrary McCune (San Francisco, California);  Irving L. Weissman (Stanford, California)
ABSTRACT Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRPα on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
FILED Monday, December 10, 2018
APPL NO 16/214507
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1774 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/41 (20180101)
Y02A 50/403 (20180101)
Y02A 50/412 (20180101)
Y02A 50/471 (20180101)
Y02A 50/478 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723812 Cowman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Mary Cowman (Mohegan Lake, New York);  Han Yuan (New York, New York);  Ripal Amin (Gujarat, India)
ABSTRACT The present invention provides a facile method for separation (fractionation) of HA in a sample over a broad M range, including low M HA, by ion exchange (IEX) chromatography. The present invention also provides an assay method for quantifying in a sample the presence of low M HA in total HA isolated from a biological source. The method involves HA fractionation according to M by use of IEX separation, followed by HA-specific assay of HA size range fractions.
FILED Friday, February 06, 2015
APPL NO 15/116393
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Polysaccharides; Derivatives Thereof
C08B 37/0072 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/66 (20130101)
G01N 33/5308 (20130101)
G01N 2400/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723944 Shenderova
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Adámas Nanotechnologies Inc. (Raleigh, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Olga Aleksandrovna Shenderova (Raleigh, North Carolina)
ABSTRACT A fluorescent diamond particle, characterized by having a surface and a diamond lattice; the particle comprising a core and a region within approximately 3 nm of the surface of the particle enriched with fluorescent color centers, where the near surface enrichment with color centers is enriched by a treatment providing in-diffusion of external dopants, as compared to particles which have not undergone the treatment. The dopant is selected from the group consisting of a nitrogen atom, a group of nitrogen atoms, silicon, and a combination thereof.
FILED Monday, June 10, 2019
APPL NO 16/436273
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/025 (20130101)
C09K 11/65 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724005 D'Lima et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Scripps Health, Inc. (San Diego, California)
ASSIGNEE(S) SCRIPPS HEALTH (San Diego, California)
INVENTOR(S) Darryl D. D'Lima (San Diego, California);  Tsaiwei Olee (San Diego, California);  Clifford W. Colwell (La Jolla, California)
ABSTRACT Disclosed herein are methods of producing chondrocytes from pluripotent stem cells. The invention further provides methods of regenerating cartilaginous tissue.
FILED Friday, September 27, 2013
APPL NO 14/431893
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/32 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0655 (20130101) Original (OR) Class
C12N 2501/15 (20130101)
C12N 2506/02 (20130101)
C12N 2533/54 (20130101)
C12N 2533/90 (20130101)
C12N 2537/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724007 Whitehead et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The Government of the USA as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Stephen S. Whitehead (Bethesda, Maryland);  Joseph E. Blaney (Gettysburg, Pennsylvania);  Brian R. Murphy (Bethesda, Maryland);  Ching-Juh Lai (Bethesda, Massachusetts)
ABSTRACT The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3′ untranslated region (3′-UTR) comprising a Δ30 mutation that removes the TL-2 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, and nucleotides additional to the Δ30 mutation deleted from the 3′-UTR that removes sequence in the 5′ direction as far as the 5′ boundary of the TL-3 homologous structure in each of the dengue serotypes 1, 2, 3, and 4, or a replacement of the 3′-UTR of a dengue virus of a first serotype with the 3′-UTR of a dengue virus of a second serotype, optionally containing the Δ30 mutation and nucleotides additional to the Δ30 mutation deleted from the 3′-UTR; and immunogenic compositions, methods of inducing an immune response, and methods of producing a dengue virus or chimeric dengue virus.
FILED Monday, October 29, 2018
APPL NO 16/173217
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/1825 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 7/045 (20130101) Original (OR) Class
C12N 2770/24122 (20130101)
C12N 2770/24162 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/386 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724026 Georgiou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) George Georgiou (Austin, Texas);  Everett Stone (Austin, Texas);  Wei-Cheng Lu (Austin, Texas)
ABSTRACT Methods and compositions relating to the engineering of an improved protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading methionine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with methionine depletion using the disclosed proteins or nucleic acids.
FILED Friday, February 01, 2019
APPL NO 16/265952
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/51 (20130101)
A61K 38/51 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/14 (20130101)
C12N 1/20 (20130101)
C12N 5/0601 (20130101)
C12N 9/88 (20130101) Original (OR) Class
C12N 15/70 (20130101)
C12N 15/74 (20130101)
C12N 15/79 (20130101)

Enzymes
C12Y 404/01001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724049 Jin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hailing Jin (Riverside, California)
ABSTRACT The present invention relates to pathogen-resistant plants. In one aspect, plants comprising a heterologous expression cassette are provided, wherein the expression cassette comprises a polynucleotide that inhibits expression of a fungal pathogen dicer-like (DCL) gene and wherein the plant has increased resistance to a fungal pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
FILED Friday, July 24, 2015
APPL NO 14/809063
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/8218 (20130101)
C12N 15/8282 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724051 Yan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Hong Yan (Philadelphia, Pennsylvania);  Shuren Liao (Philadelphia, Pennsylvania)
ABSTRACT A gene of interest and the gene encoding hypoxanthine-aminopterin-thymidine (HPRT) can be co-targeted for Casp9 nuclease-mediated editing or alteration in a cell. Based on whether the HPRT gene is altered to encode a non-functional protein, or is not so-altered, the co-targeted cells can be selected and counter-selected. HPRT co-targeting can be used to sequentially disrupt as many genes of interest as cell viability permits.
FILED Friday, October 06, 2017
APPL NO 15/726531
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1077 (20130101)
C12N 15/11 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 15/1137 (20130101)
C12N 2310/20 (20170501)
C12N 2320/34 (20130101)

Enzymes
C12Y 204/02008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724076 Sarkar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Casim Ali Sarkar (Minneapolis, Minnesota);  Igor Dodevski (Minneapolis, Minnesota)
ABSTRACT Materials and methods for specifically isolating and identifying biomolecules that bind to selected targets.
FILED Thursday, October 05, 2017
APPL NO 15/725991
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 2317/92 (20130101)
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1034 (20130101)
C12N 15/1055 (20130101)
C12N 15/1055 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/005 (20130101)
C12Q 1/6811 (20130101) Original (OR) Class
C12Q 1/6823 (20130101)
C12Q 1/6834 (20130101)
C12Q 2521/107 (20130101)
C12Q 2563/179 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6845 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724079 Mitra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Lucira Health, Inc. (Emeryville, California)
ASSIGNEE(S) Lucira Health, Inc. (Emeryville, California)
INVENTOR(S) Debkishore Mitra (Berkeley, California);  Ivan Krastev Dimov (Union City, California);  John Robert Waldeisen (Berkley, California)
ABSTRACT Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED Wednesday, March 20, 2019
APPL NO 16/359913
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2527/119 (20130101)
C12Q 2527/125 (20130101)
C12Q 2563/173 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724081 Poritz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) BioFire Diagnostics, LLC (Salt Lake City, Utah);  University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) BioFire Diagnostics, LLC (Salt Lake City, Utah);  University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Mark Aaron Poritz (Salt Lake City, Utah);  Anne Jeannette Blaschke-Bonkowsky (Salt Lake City, Utah)
ABSTRACT Methods and containers are provided for identifying a species, illustratively a bacterial species. Illustrative methods comprise amplifying various genes in the nucleic acid from the bacterial species in a single reaction mixture using pairs of outer first-stage primers designed to hybridize to generally conserved regions of the respective genes to generate a plurality of first-stage amplicons, dividing the reaction mixture into a plurality of second-stage reactions, each using a unique pair of second-stage primers, each pair of second-stage primers specific for a target bacterial species or subset of bacterial species, detecting which of the second-stage reactions amplified, and identifying the bacterial species based on second-stage amplification. Methods for determining antibiotic resistance are also provided, such methods also using first-stage primers for amplifying genes known to affect antibiotic resistance a plurality of the second-stage reactions wherein each pair of second-stage primers specific for a specific gene for conferring antibiotic resistance.
FILED Wednesday, July 26, 2017
APPL NO 15/660609
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/527 (20130101)
B01L 3/50273 (20130101)
B01L 7/525 (20130101)
B01L 2200/16 (20130101)
B01L 2200/141 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0829 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0478 (20130101)
B01L 2400/0481 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/689 (20130101)
C12Q 2525/15 (20130101)
C12Q 2549/119 (20130101)
C12Q 2600/16 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724089 Bashir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Rashid Bashir (Champaign, Illinois);  Anurup Ganguli (Champaign, Illinois);  Farhad Kosari (Rochester, Minnesota)
ABSTRACT Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique.
FILED Friday, October 06, 2017
APPL NO 15/727026
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/5085 (20130101)
B01L 3/50851 (20130101)
B01L 2200/0642 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0858 (20130101)
B01L 2300/0893 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101)
C12N 15/1003 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2521/107 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101)
G01N 2001/282 (20130101)
G01N 2001/2873 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
G16B 30/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724091 Meagher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Robert Meagher (Mountain House, California);  Chung-Yan Koh (Dublin, California);  Yooli Kim Light (Pleasanton, California);  Cameron Scott Ball (Sunnyvale, California)
ABSTRACT The present invention relates to probes and primers beneficial for conducting amplification assays, such as those including loop-mediated isothermal amplification reactions. Also described herein are methods for detecting targets using such probes and/or primers.
FILED Wednesday, January 27, 2016
APPL NO 15/008285
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724099 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Channing Yu (Cambridge, Massachusetts);  Todd R. Golub (Newton, Massachusetts)
ABSTRACT Methods to simultaneously test and screen multiplexed, mixed cell populations, e.g., populations comprising genetically heterogeneous cancer cells, in common conditions.
FILED Thursday, March 14, 2013
APPL NO 14/385545
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2543/101 (20130101)
C12Q 2563/185 (20130101)
C12Q 2600/112 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724100 Arora et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Institute for Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Sanjeevani Arora (Philadelphia, Pennsylvania);  Greg Enders (Philadelphia, Pennsylvania);  Erica Golemis (Philadelphia, Pennsylvania);  Emmanuelle Nicolas (Philadelphia, Pennsylvania);  Ilya Serebriiskii (Philadelphia, Pennsylvania)
ABSTRACT Systems and methods for mitigating prostate cancer development are provided. Peripheral blood cells may be evaluated for the presence or quantity of gamma-H2AX foci, and/or for gene alterations encoding a protein with impaired or lack of function, for example, because the encoded protein is truncated, and correlating with prostate cancer development. Such nucleic acids may encode proteins from or peripheral to the DNA damage repair pathway and/or androgen receptor signaling pathway, or that are otherwise correlated with prostate cancer development. Such genes include one or more of AKR1C1, PALB2, APTX, BLM, BRCA1, CTBP1, DDB2, FANCA, FANCL, MBD5, MSH3, NEIL3, RAD51D, RAD54L2, SP1, TP53BP1, UBE2D3, UBE2V2, NRIP1, EFCAB6, CRISP3, PAPSS2, ATP6V0A2, ALG13, MGAT2, B3GAT3, DOLK, FLT3, ASXL1, KDR, or NOTCH2.
FILED Wednesday, September 16, 2015
APPL NO 14/855999
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57434 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724948 Weissleder et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Ralph Weissleder (Peabody, Massachusetts);  Hakho Lee (Acton, Massachusetts);  Hyungsoon Im (Peabody, Massachusetts);  Cesar Castro (Reading, Massachusetts)
ABSTRACT The disclosure features systems and methods for measuring and diagnosing target constituents bound to labeling particles in a sample. The systems include a radiation source, a sample holder, a detector configured to obtain one or more diffraction patterns of the sample each including information corresponding to optical properties of sample constituents, and an electronic processor configured to, for each of the one or more diffraction patterns: (a) analyze the diffraction pattern to obtain amplitude information and phase information corresponding to the sample constituents; (b) identify one or more particle-bound target sample constituents based on at least one of the amplitude information and the phase information; and (c) determine an amount of at least one of the particle-bound target sample constituents in the sample based on at least one of the amplitude information and the phase information.
FILED Monday, July 02, 2018
APPL NO 16/025615
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/708 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/06 (20130101)
G01N 15/0211 (20130101)
G01N 15/0227 (20130101)
G01N 15/0612 (20130101)
G01N 21/4788 (20130101) Original (OR) Class
G01N 33/56972 (20130101)
G01N 33/57407 (20130101)
G01N 33/57411 (20130101)
G01N 2015/0065 (20130101)
G01N 2015/0693 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1486 (20130101)

Holographic Processes or Apparatus
G03H 1/0443 (20130101)
G03H 1/0866 (20130101)
G03H 2001/0447 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724974 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Yihua Bruce Yu (Ellicott City, Maryland);  Marc Taraban (Gaithersburg, Maryland);  Yue Feng (Niantic, Connecticut)
ABSTRACT The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation.
FILED Wednesday, November 13, 2019
APPL NO 16/682157
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101) Original (OR) Class
G01N 33/15 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/448 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725026 Murphy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York);  Westmead Institute For Medical Research (Westmead, NSW, Australia);  Western Sydney Local Health District (Westmead, NSW, Australia)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York);  Westmead Institute For Medical Research (Westmead, Australia);  Western Sydney Local Health District (Westmead, Australia)
INVENTOR(S) Barbara Murphy (Boston, Massachusetts);  Philip J. O'Connell (Sydney, Australia)
ABSTRACT A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
FILED Monday, November 13, 2017
APPL NO 15/810861
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 13/12 (20180101)

Peptides
C07K 14/47 (20130101)
C07K 14/4705 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/5308 (20130101) Original (OR) Class
G01N 33/6893 (20130101)
G01N 2333/775 (20130101)
G01N 2800/50 (20130101)
G01N 2800/54 (20130101)
G01N 2800/085 (20130101)
G01N 2800/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725032 Duffy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Quanterix Corporation (Billerica, Massachusetts)
ASSIGNEE(S) Quanterix Corporation (Billerica, Massachusetts)
INVENTOR(S) David C. Duffy (Arlington, Massachusetts);  David M. Rissin (Somerville, Massachusetts);  David R. Walt (Boston, Massachusetts);  David Fournier (Northborough, Massachusetts);  Cheuk Kan (Waltham, Massachusetts)
ABSTRACT The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles with respect to a plurality of capture objects. At least a portion of the plurality of capture objects may be spatially separated into a plurality of locations. A measure of the concentration of analyte molecules in a fluid sample may be determined, at least in part, on the number of reaction vessels comprising an analyte molecule immobilized with respect to a capture object. In some cases, the assay may additionally comprise steps including binding ligands, precursor labeling agents, and/or enzymatic components.
FILED Friday, April 14, 2017
APPL NO 15/487889
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54306 (20130101)
G01N 33/54313 (20130101)
G01N 33/54393 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725036 Cornish et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Virginia Wood Cornish (New York, New York);  Nili Ostrov (Boston, Massachusetts);  Miguel Jimenez (New York, New York);  Sonja Billerbeck (New York, New York)
ABSTRACT The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample.
FILED Tuesday, May 16, 2017
APPL NO 15/596837
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)
C12Q 1/005 (20130101)
C12Q 1/06 (20130101)
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/566 (20130101) Original (OR) Class
G01N 33/569 (20130101)
G01N 33/5023 (20130101)
G01N 33/5038 (20130101)
G01N 33/5695 (20130101)
G01N 33/56911 (20130101)
G01N 33/56916 (20130101)
G01N 33/56961 (20130101)
G01N 2333/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725040 Das et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio);  THE OHIO STATE UNIVERSITY (Columbus, Ohio)
ASSIGNEE(S) NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio);  THE OHIO STATE UNIVERSITY (Columbus, Ohio)
INVENTOR(S) Subinoy Das (Columbus, Ohio);  Lauren O. Bakaletz (Hilliard, Ohio)
ABSTRACT The invention provides for a proteomic approach for identification of specific bacterial protein profiles that may be used in the development of methods for the diagnosis of bacterial chronic sinusitis. The invention provides for methods for determining the presence of pathogenic bacteria in the upper respiratory tract of a subject using protein profiles of the pathogenic bacteria. The invention also provides for methods of diagnosing a bacterial infection of the upper respiratory tract of a subject using protein profiles of a pathogenic bacteria. In addition, the invention provides for devices, immunoassays and kits for identifying pathogenic bacteria in the upper respiratory tract.
FILED Monday, June 24, 2019
APPL NO 16/450476
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0045 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101) Original (OR) Class
G01N 2333/285 (20130101)
G01N 2800/12 (20130101)
G01N 2800/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725041 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Versiti Blood Research Institute Foundation, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) VERSITI BLOOD RESEARCH INSTITUTE FOUNDATION, INC. (Milwaukee, Wisconsin)
INVENTOR(S) Peter Jay Newman (Bayside, Wisconsin);  Sridhar Rao (Brookfield, Wisconsin);  Nanyan Zhang (Wauwatosa, Wisconsin);  Huiying Zhi (Brookfield, Wisconsin)
ABSTRACT Methods of creating cells expressing specific platelet alloantigens by combining gene editing techniques and cell culture differentiation or expansion techniques employing pluripotent cells, including the steps of transfecting pluripotent cells with a plasmid encoding one or more guide RNAs targeting within a platelet alloantigen target locus and a nuclease in the presence of an HDR repair oligo and culturing the resulting cells to expand their numbers or to create a differentiated cell type of interest.
FILED Tuesday, November 03, 2015
APPL NO 14/931321
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0644 (20130101)
C12N 5/0696 (20130101)
C12N 15/85 (20130101)
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)
C12N 2800/80 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56977 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725053 Qian et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington);  University of Washington (Seattle, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington);  University of Washington (Seattle, Washington)
INVENTOR(S) Wei-Jun Qian (Richland, Washington);  Tujin Shi (Richland, Washington);  Alvin Y. Liu (Everett, Washington)
ABSTRACT Methods are provided for treating a subject with prostate cancer and/or diagnosing a subject at risk for prostate cancer, which can include measuring increased expression of at least two prostate cancer-related molecules in a sample obtained from a subject, including the prostate cancer-related molecules AGR2, AGR3, CRISP3, CCL3, CEACAM5, CEACAM6, IL24, MMP9, CXCL14, CD90, POSTN, and SFRP4. The methods can include administering at therapy to a subject with prostate cancer. Methods are provided for treating a subject with intermediate- or high-risk prostate cancer, which can include measuring increased expression of MMP9 in a sample obtained from a subject compared to a control representing expression of MMP9 expected in a sample from a subject who has low-risk prostate cancer.
FILED Tuesday, December 12, 2017
APPL NO 15/839635
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/37 (20130101)
C12Q 1/533 (20130101)

Enzymes
C12Y 304/24035 (20130101)
C12Y 503/04001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
G01N 33/6863 (20130101)
G01N 33/6869 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 33/57434 (20130101)
G01N 2333/47 (20130101)
G01N 2333/52 (20130101)
G01N 2333/54 (20130101)
G01N 2333/99 (20130101)
G01N 2333/70503 (20130101)
G01N 2333/70596 (20130101)
G01N 2333/96486 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725055 Pluth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Oregon (Eugene, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon)
INVENTOR(S) Michael D. Pluth (Eugene, Oregon);  Andrea Steiger (Eugene, Oregon);  Yu Zhao (Eugene, Oregon)
ABSTRACT Disclosed herein are embodiments of donor compounds that can be used to produce H2S from COS or CS2 released from the donor compounds. In some embodiments, the donor compounds can indirectly produce H2S after being exposed to a reactive component in a triggering event. In other embodiments, the donor compounds can indirectly regenerate H2S after reacting with an H2S analyte. The donor compounds disclosed herein can be used for analytical techniques, disease diagnostics, and/or therapeutic applications. Methods of making and using the donor compounds also are provided herein.
FILED Monday, April 10, 2017
APPL NO 15/484023
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 275/70 (20130101)
C07C 333/08 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/527 (20130101)

Enzymes
C12Y 402/01001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
G01N 33/84 (20130101) Original (OR) Class
G01N 2800/7009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725058 Xiao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Yi Xiao (Miami, Florida);  Yingping Luo (Miami, Florida);  Haixiang Yu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Miami, Florida);  Yingping Luo (Miami, Florida);  Haixiang Yu (Miami, Florida)
ABSTRACT The subject invention provides methods, assays, and products for visual detection of small-molecule targets in a sample in both clinical and field settings within minutes. The subject invention is based on an aptamer sensor that reports the presence of small-molecule target via a sensitive colorimetric signal for naked-eye detection. The aptamer sensor is a CBSAzyme-based sensor having both target-mediated cooperative behavior of the CBSA and peroxidase-mimicking catalytic activity of DNAzyme. The subject invention also provides methods of using the CBSAzyme-based sensor.
FILED Friday, November 02, 2018
APPL NO 16/179336
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
G01N 33/9486 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725133 Quist et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Brady J. Quist (Stanford, California);  Brian A. Hargreaves (Menlo Park, California)
ABSTRACT A method for generating a magnetic resonance image of an object in a magnetic resonance imaging (MRI) system, wherein the object contains at least one metallic implant is provided. The MRI system provides multiple excitations of at least part of the object. The MRI system reads out image signals from the object. The MRI system saves the readout image signals as image data. A field-map is generated from the image data using a goodness-of-fit process which uses a goodness-of-fit metric, matched-filter, and/or similar fitting techniques to fit expected signals from each excitation to the image data.
FILED Friday, April 07, 2017
APPL NO 15/481749
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/243 (20130101)
G01R 33/4833 (20130101) Original (OR) Class
G01R 33/5608 (20130101)
G01R 33/56563 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726552 Sun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Phillip Zhe Sun (Woburn, Massachusetts);  Iris Yuwen Zhou (Malden, Massachusetts)
ABSTRACT The present disclosure relates to systems and methods for determining quantitative chemical exchange or exchangeable proton information from a region-of-interest in a subject. The methods and systems use adaptive fitting to quantify magnetic resonance (MR) data, such as chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) images, using initial values based on, for example, Lorentzian fitting. Images are iteratively less downsampled until quantitative maps of desired resolution are obtained. Such an approach allows for reliable fitting at a faster fitting speed, and is less susceptible to suboptimal signal to noise (SNR) than conventional methods.
FILED Tuesday, March 20, 2018
APPL NO 15/926954
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/48 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0014 (20130101) Original (OR) Class
G06T 2207/10096 (20130101)
G06T 2207/20016 (20130101)
G06T 2207/20104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726945 Sanborn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) John Zachary Sanborn (Santa Cruz, California);  David Haussler (Santa Cruz, California)
ABSTRACT A differential sequence object is constructed on the basis of alignment of sub-strings via incremental synchronization of sequence strings using known positions of the sub-strings relative to a reference genome sequence. An output file is then generated that comprises only relevant changes with respect to the reference genome.
FILED Friday, March 31, 2017
APPL NO 15/476337
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 3/04845 (20130101)
G06F 40/169 (20200101)

Computer Systems Based on Specific Computational Models
G06N 7/005 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/24 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 30/00 (20190201)
G16B 50/00 (20190201) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)

Technologies for Adaptation to Climate Change
Y02A 90/22 (20180101)
Y02A 90/26 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10722130 Banet et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ASSIGNEE(S) SOTERA WIRELESS, INC. (San Diego, California)
INVENTOR(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ABSTRACT The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
FILED Tuesday, December 27, 2011
APPL NO 13/338216
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0008 (20130101)
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/029 (20130101)
A61B 5/0205 (20130101)
A61B 5/0245 (20130101)
A61B 5/0295 (20130101) Original (OR) Class
A61B 5/0535 (20130101)
A61B 5/681 (20130101)
A61B 5/725 (20130101)
A61B 5/746 (20130101)
A61B 5/0816 (20130101)
A61B 5/1116 (20130101)
A61B 5/02028 (20130101)
A61B 5/02427 (20130101)
A61B 5/6823 (20130101)
A61B 5/6824 (20130101)
A61B 5/6826 (20130101)
A61B 5/6833 (20130101)
A61B 5/7239 (20130101)
A61B 5/14542 (20130101)
A61B 5/14551 (20130101)
A61B 2562/04 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722131 Banet et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ASSIGNEE(S) SOTERA WIRELESS, INC. (San Diego, California)
INVENTOR(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ABSTRACT The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
FILED Tuesday, December 27, 2011
APPL NO 13/338228
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0008 (20130101)
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/029 (20130101)
A61B 5/0205 (20130101)
A61B 5/0245 (20130101)
A61B 5/0295 (20130101) Original (OR) Class
A61B 5/0535 (20130101)
A61B 5/681 (20130101)
A61B 5/725 (20130101)
A61B 5/746 (20130101)
A61B 5/0816 (20130101)
A61B 5/1116 (20130101)
A61B 5/02028 (20130101)
A61B 5/02427 (20130101)
A61B 5/6823 (20130101)
A61B 5/6824 (20130101)
A61B 5/6826 (20130101)
A61B 5/6833 (20130101)
A61B 5/7239 (20130101)
A61B 5/14542 (20130101)
A61B 5/14551 (20130101)
A61B 2562/04 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722132 Banet et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ASSIGNEE(S) SOTERA WIRELESS, INC. (San Diego, California)
INVENTOR(S) Matt Banet (Kihei, Hawaii);  Isaac Henry (La Mesa, California);  Donald Bernstein (Rancho Santa Fe, California)
ABSTRACT The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
FILED Tuesday, December 27, 2011
APPL NO 13/338238
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0008 (20130101)
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/029 (20130101)
A61B 5/0205 (20130101)
A61B 5/0245 (20130101)
A61B 5/0295 (20130101) Original (OR) Class
A61B 5/0535 (20130101)
A61B 5/681 (20130101)
A61B 5/725 (20130101)
A61B 5/746 (20130101)
A61B 5/0816 (20130101)
A61B 5/1116 (20130101)
A61B 5/02028 (20130101)
A61B 5/02427 (20130101)
A61B 5/6823 (20130101)
A61B 5/6824 (20130101)
A61B 5/6826 (20130101)
A61B 5/6833 (20130101)
A61B 5/7239 (20130101)
A61B 5/14542 (20130101)
A61B 5/14551 (20130101)
A61B 2562/04 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722174 Pang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Changhyun Pang (Suwon, South Korea);  Zhenan Bao (Stanford, California)
ABSTRACT Various aspects as described herein are directed to skin-conformal sensor devices and methods of using the same. As consistent with one or more embodiments, a sensor device includes an upper portion and lower portion. The upper portion includes a plurality of layers including at least one sensor. The lower portion includes a layer of microstructures configured and arranged to interface with skin of a subject and to interlock the skin with the at least one sensor.
FILED Friday, July 10, 2015
APPL NO 14/796800
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0002 (20130101)
A61B 5/0402 (20130101)
A61B 5/0476 (20130101)
A61B 5/02055 (20130101)
A61B 5/02444 (20130101)
A61B 5/6833 (20130101) Original (OR) Class
A61B 5/7246 (20130101)
A61B 2562/028 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722637 Humes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) SeaStar Medical, Inc. (Cardiff-By-The-Sea, California)
ASSIGNEE(S) SeaStar Medical, Inc. (Denver, Colorado)
INVENTOR(S) H. David Humes (Ann Arbor, Michigan);  Deborah A. Buffington (Ann Arbor, Michigan)
ABSTRACT The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions that affect myocardial function and to related methods. The cartridge can be used in treating a subject with myocardial dysfunction, such as a subject with chronic heart failure and/or acute decompensated heart failure.
FILED Thursday, April 20, 2017
APPL NO 15/492518
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/194 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/16 (20130101)
A61M 1/34 (20130101)
A61M 1/1625 (20140204)
A61M 1/3472 (20130101)
A61M 1/3486 (20140204) Original (OR) Class
A61M 1/3666 (20130101)
A61M 1/3679 (20130101)
A61M 1/3687 (20130101)
A61M 2202/0427 (20130101)
A61M 2202/0439 (20130101)
A61M 2205/126 (20130101)
A61M 2210/125 (20130101)

Separation
B01D 61/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722743 Landers et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) John Landers (Riverton, New Jersey);  Alexander V. Neimark (Princeton, New Jersey);  Tewodros Asefa (Princeton, New Jersey);  Aleksey Vishnyakov (North Brunswick, New Jersey);  Anandarup Goswami (Riverton, New Jersey);  Jonathan Colon Ortiz (Highland Park, New Jersey)
ABSTRACT A multi-catalytic material that includes a polyelectrolyte membrane and methods of preparing the same are provided herein.
FILED Friday, May 13, 2016
APPL NO 15/154219
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 5/00 (20130101) Original (OR) Class

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/06 (20130101)
B01J 27/188 (20130101)
B01J 31/06 (20130101)
B01J 31/10 (20130101)
B01J 31/28 (20130101)
B01J 31/34 (20130101)
B01J 31/38 (20130101)
B01J 35/06 (20130101)
B01J 35/0013 (20130101)
B01J 35/065 (20130101)
B01J 37/035 (20130101)
B01J 37/0211 (20130101)
B01J 37/0219 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/225 (20130101)
C08J 5/2243 (20130101)
C08J 5/2275 (20130101)
C08J 5/2281 (20130101)
C08J 7/06 (20130101)
C08J 7/0423 (20200101)
C08J 2327/18 (20130101)
C08J 2353/02 (20130101)
C08J 2400/12 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 11/44 (20130101)
D06M 11/45 (20130101)
D06M 11/46 (20130101)
D06M 11/49 (20130101)
D06M 11/50 (20130101)
D06M 15/227 (20130101)
D06M 15/233 (20130101)
D06M 15/256 (20130101)
D06M 15/3566 (20130101)
D06M 16/00 (20130101)
D06M 23/08 (20130101)
D06M 2400/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723453 Scott et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Mark W. Scott (Bethany, Connecticut);  Colin Kemater Bunting (Guilford, Connecticut)
ABSTRACT A flying wing vertical take-off and landing (VTOL) aircraft includes an empennageless-fuselage from which foldable wings extend outwardly, an empennageless-nacelle supported on each of the wings and a rigid rotor propeller disposed on each empennageless-nacelle, each of the propellers being drivable to rotate about only a single rotational axis defined along a longitudinal axis of the corresponding empennageless-nacelle and being fully cyclically controllable.
FILED Thursday, November 19, 2015
APPL NO 15/544698
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 25/04 (20130101)
B64C 29/02 (20130101) Original (OR) Class
B64C 2201/028 (20130101)
B64C 2201/048 (20130101)
B64C 2201/088 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723684 Reno et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) UNIVERSITY OF DELAWARE (Newark, Delaware);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Aberdeen Proving Ground, Maryland);  ROWAN UNIVERSITY (Glassboro, New Jersey)
ASSIGNEE(S) UNIVERSITY OF DELAWARE (Newark, Delaware);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Aberdeen Proving Ground, Maryland);  ROWAN UNIVERSITY (Glassboro, New Jersey)
INVENTOR(S) Kaleigh Havery Reno (Newark, Delaware);  Joseph Francis Stanzione, III (Wilmington, Delaware);  Richard Patrick Wool (Newark, Delaware);  Joshua M. Sadler (Middle River, Maryland);  John Joseph Lascala (Wilmington, Delaware);  Eric David Hernandez (Blackwood, New Jersey)
ABSTRACT A compound is provided according to structure 4, (4) wherein n has a value from 0 to 48 and Z is hydroxyl or a benzene ring bearing substituents R11-R15, wherein R1-R15 are each individually selected from the group consisting of H, allyl, alkyl, alkoxy, phenyl, phenoxy, halide, hydroxyl, glycidyl, (meth)acryloyl, 3-(meth)acryloyl-2-hydroxy-1-propoxy, 2,3-epoxypropyl, maleate, and structure (a) wherein at least one of R1-R5, at least one of R6-R10, and at least one of R11-R15 is hydroxyl or an ether or ester derived from it and one of the R6-R10 groups is replaced by a direct bond to the CXY group.
FILED Wednesday, May 27, 2015
APPL NO 15/313656
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 41/09 (20130101)
C07C 43/295 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/10 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/3215 (20130101)
C08G 18/3243 (20130101)
C08G 18/7621 (20130101)
C08G 59/063 (20130101)
C08G 59/245 (20130101)
C08G 59/5026 (20130101)
C08G 63/193 (20130101)
C08G 63/547 (20130101)
C08G 64/06 (20130101)
C08G 64/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723834 Davis
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Matthew C. Davis (Ridgecrest, California)
ABSTRACT The invention generally relates to novel poly-substituted cis stilbenes, their synthesis, their purification, and their use in thermoset resins. These novel cis stilbenes give rise to thermoset resins with greatly improved processing characteristics such as lower melting temperature and lower viscosity; resulting in polymers and composites having greatly improved thermal stability.
FILED Friday, April 13, 2018
APPL NO 15/877758
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/7685 (20130101) Original (OR) Class
C08G 63/193 (20130101)
C08G 65/42 (20130101)
C08G 2650/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724002 Slukvin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Igor I. Slukvin (Verona, Wisconsin);  James A. Thomson (Madison, Wisconsin);  Maksym A. Vodyanyk (Madison, Wisconsin);  Maryna E. Gumenyuk (Madison, Wisconsin)
ABSTRACT Methods and compositions of erythroid cells that produce adult β-hemoglobin, generated by culturing CD31+, CD31+/CD34+ or CD34+ cells from embryonic stem cells under serum-free culture conditions.
FILED Thursday, April 05, 2018
APPL NO 15/946101
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0641 (20130101) Original (OR) Class
C12N 2500/25 (20130101)
C12N 2501/14 (20130101)
C12N 2501/23 (20130101)
C12N 2501/39 (20130101)
C12N 2501/125 (20130101)
C12N 2501/145 (20130101)
C12N 2502/1394 (20130101)
C12N 2506/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724070 Hassett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Daniel J. Hassett (Cincinnati, Ohio);  Shengchang Su (Cincinnati, Ohio);  Thomas J. Lamkin (Cincinnati, Ohio);  Roland Saldanha (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio);  Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Daniel J. Hassett (Cincinnati, Ohio);  Shengchang Su (Cincinnati, Ohio);  Thomas J. Lamkin (Cincinnati, Ohio);  Roland Saldanha (Cincinnati, Ohio)
ABSTRACT Stable, constitutively expressed, chromosomal fluorescent transcriptional fusions in bacterial pathogens and methods of using the same to screen candidate compounds for anti-bacterial efficacy.
FILED Thursday, November 14, 2013
APPL NO 14/080247
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/43595 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724375 Prescott et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jeffrey Miles McMillen Prescott (Somerville, Massachusetts);  Richard Alan Wesling (Cincinnati, Ohio);  Peter Andrew Simeone (Byfield, Massachusetts)
ABSTRACT A damper seat for a ring damper that redirects axial loads and is disposed within a gas turbine engine with at least one disk rotatable about a rotational axis and having a disk neutral axis extending radially from the rotational axis.
FILED Friday, February 12, 2016
APPL NO 15/042187
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/10 (20130101) Original (OR) Class
F01D 5/12 (20130101)
F01D 9/041 (20130101)
F01D 11/001 (20130101)
F01D 25/04 (20130101)

Non-positive-displacement Pumps
F04D 29/321 (20130101)
F04D 29/668 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/96 (20130101)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/14 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/672 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724384 Chuong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Conway Chuong (Manchester, California);  Ross Wilson (South Glastonbury, Connecticut)
ABSTRACT A component retaining assembly includes a housing including a circumferential slot. A component is mated to the housing. The component includes a first face including at least two tabs. The at least two tabs extending at outward from the first face at least partially past a portion of the circumferential slot. A retaining ring is disposed within the circumferential slot and abuts the first face of the component. The at least two tabs overlap a portion of the retaining ring. A gas turbine engine and a method are also disclosed.
FILED Thursday, September 01, 2016
APPL NO 15/253957
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/30 (20130101) Original (OR) Class
F01D 5/3007 (20130101)
F01D 5/3015 (20130101)
F01D 9/042 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724402 Bejleri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Rigels Bejleri (Southington, Connecticut);  Patrick M. Devaney (Newington, Connecticut)
ABSTRACT A duct liner assembly for a gas turbine engine includes a first ring and a second ring. Also included is a first duct liner having a first end and a second end, the first duct liner mounted proximate the first end of the first duct liner to the first ring. Further included is a second duct liner having a first end and a second end, the second duct liner mounted proximate the second end of the second duct liner to the second ring. Yet further included is a coupling assembly including a threaded insert, a retaining bracket, and a threaded fastener extending through the retaining bracket and in threaded engagement with the threaded insert to couple the retaining bracket to the second duct liner.
FILED Monday, June 26, 2017
APPL NO 15/633109
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/005 (20130101)
F01D 25/24 (20130101) Original (OR) Class
F01D 25/243 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)

Jet-propulsion Plants
F02K 1/80 (20130101)
F02K 1/82 (20130101)

Non-positive-displacement Pumps
F04D 29/522 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2230/642 (20130101)
F05D 2240/14 (20130101)
F05D 2260/30 (20130101)
F05D 2260/31 (20130101)
F05D 2260/36 (20130101)
F05D 2300/171 (20130101)
F05D 2300/603 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724467 Koeberlein et al.
FUNDED BY
Department of Defense (DOD)
Defense Mobility Enterprise (DME)
National Advanced Mobility Consortium (NAMC)
APPLICANT(S) CUMMINS INC. (Columbus, Indiana)
ASSIGNEE(S) Cummins Inc. (Columbus, Indiana)
INVENTOR(S) David E. Koeberlein (Columbus, Indiana);  J. Steven Kolhouse (Columbus, Indiana)
ABSTRACT A piston for an opposed-piston engine has a thermal barrier coating on at least the piston crown. The piston, at least the piston crown, is made of titanium or a titanium alloy. The thermal barrier coating includes a bonding material and a ceramic material. The bonding material can be present in the thermal barrier coating at an interface of the thermal barrier coating and the bulk of the piston material. The ceramic material can be a high R-Value material. In particular, the piston with a thermal barrier coating can be an exhaust piston for an opposed-piston engine.
FILED Friday, October 27, 2017
APPL NO 15/796302
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 28/042 (20130101)
C23C 28/3215 (20130101)
C23C 28/3455 (20130101)

Machines or Engines, in General or of Positive-displacement Type, e.g Steam Engines
F01B 7/02 (20130101)
F01B 7/14 (20130101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 23/06 (20130101)
F02B 75/28 (20130101)
F02B 75/282 (20130101)

Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines
F02F 3/04 (20130101)
F02F 3/14 (20130101) Original (OR) Class
F02F 3/22 (20130101)
F02F 3/26 (20130101)
F02F 3/0084 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724478 Morgan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota)
ASSIGNEE(S) Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota)
INVENTOR(S) Richard E. Morgan (Huntsville, Alabama);  Craig L. Meeks (Meridianville, Alabama)
ABSTRACT Insulation materials have a coating of a partially cured polymer on a plurality of fibers, and the plurality of coated fibers in a cross-linked polymeric matrix. Insulation may be formed by applying a preceramic polymer to a plurality of fibers, heating the preceramic polymer to form a partially cured polymer over at least portions of the plurality of fibers, disposing the plurality of fibers in a polymeric material, and curing the polymeric material. A rocket motor may be formed by disposing a plurality of coated fibers in an insulation precursor, curing the insulation precursor to form an insulation material without sintering the partially cured polymer, and providing an energetic material over the polymeric material. An article includes an insulation material over at least one surface.
FILED Thursday, December 01, 2016
APPL NO 15/366518
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/00 (20130101)
C04B 35/83 (20130101)
C04B 35/6269 (20130101)
C04B 35/62863 (20130101)
C04B 35/62871 (20130101)
C04B 2235/483 (20130101)
C04B 2235/5212 (20130101)
C04B 2235/5248 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/36 (20130101)

Jet-propulsion Plants
F02K 1/822 (20130101) Original (OR) Class
F02K 9/00 (20130101)
F02K 9/32 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2300/6033 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/308 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/1362 (20150115)
Y10T 428/249921 (20150401)
Y10T 442/2631 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724543 Roberge
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Gary D. Roberge (Tolland, Connecticut)
ABSTRACT A variable-pitch vane system for a gas turbine engine includes a plurality of vanes and a synchronization ring assembly operably connected to the plurality of vanes. The synchronization ring assembly includes a first synchronization ring, a second synchronization ring and a bridge bracket connecting the first synchronization ring to the second synchronization ring. The bridge bracket includes a first face sheet, a second face sheet, a honeycomb core located between the first face sheet and the second face sheet, a first attachment feature located at a first end of the bridge bracket at which the first synchronization ring is secured, and a second attachment feature located at a second end of the bridge bracket at which the second synchronization ring is secured.
FILED Friday, August 11, 2017
APPL NO 15/674646
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/162 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)

Non-positive-displacement Pumps
F04D 29/522 (20130101)
F04D 29/542 (20130101)
F04D 29/563 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/233 (20130101)
F05D 2250/283 (20130101)
F05D 2300/10 (20130101)
F05D 2300/522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724625 Karlak
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Aviation and Missile Center (CCDC AVMC)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Matthew J. Karlak (Plymouth, Connecticut)
ABSTRACT A gearbox assembly having a driven assembly includes a drive hub having gear posts, the drive hub being rotatable about an axis. The gearbox assembly additionally includes a plurality of planetary gears and an intermediate component coupling one of the plurality of planetary gears to a corresponding gear post. The intermediate component has sufficient flexibility to maintain the planetary gears in meshing engagement with the driven assembly within the gearbox assembly when one of the planetary gears is misaligned with the corresponding gear post.
FILED Tuesday, February 20, 2018
APPL NO 15/900490
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/14 (20130101)

Gearing
F16H 1/28 (20130101)
F16H 57/12 (20130101)
F16H 57/021 (20130101)
F16H 57/082 (20130101) Original (OR) Class
F16H 57/0482 (20130101)
F16H 2057/085 (20130101)
F16H 2057/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724836 Hardt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee R. Hardt (Ridgecrest, California);  Donald L. Burnett (Spearfish, South Dakota);  Josiah S. Garfield (Ridgecrest, California);  Robert A. Koontz (Anchorage, Alaska);  Eric K. Wooding (Ridgecrest, California);  Que T. BuiDang (Ridgecrest, California)
ABSTRACT The disclosed embodiments are directed to enhancing insensitive munitions performance. Some of the embodiments employ an outgassing pad having unique geometrical configurations, compositions, and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into entire cook-off mitigation systems for insensitive munitions improvements.
FILED Monday, August 27, 2018
APPL NO 16/113786
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 17/16 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/20 (20130101)
F42B 12/207 (20130101) Original (OR) Class
F42B 39/14 (20130101)
F42B 39/20 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725021 Parker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Kevin Kit Parker (Cambridge, Massachusetts);  Josue A. Goss (Cambridge, Massachusetts);  Anna Grosberg (Irvine, California);  Patrick W. Alford (Minneapolis, Minnesota);  Adam W. Feinberg (Pittsburgh, Pennsylvania);  Ashutosh Agarwal (Miami, Florida);  Megan Laura McCain (Culver City, California);  Johan Ulrik Lind (Boston, Massachusetts)
ABSTRACT The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays.
FILED Friday, September 01, 2017
APPL NO 15/693565
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5008 (20130101) Original (OR) Class
G01N 33/5088 (20130101)
G01N 2500/04 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725036 Cornish et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Virginia Wood Cornish (New York, New York);  Nili Ostrov (Boston, Massachusetts);  Miguel Jimenez (New York, New York);  Sonja Billerbeck (New York, New York)
ABSTRACT The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample.
FILED Tuesday, May 16, 2017
APPL NO 15/596837
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)
C12Q 1/005 (20130101)
C12Q 1/06 (20130101)
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/566 (20130101) Original (OR) Class
G01N 33/569 (20130101)
G01N 33/5023 (20130101)
G01N 33/5038 (20130101)
G01N 33/5695 (20130101)
G01N 33/56911 (20130101)
G01N 33/56916 (20130101)
G01N 33/56961 (20130101)
G01N 2333/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725054 Wang et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  THE RESEARCH FOUNDATION FOR STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida);  The Research Foundation For The State University of New York (Albany, New York)
INVENTOR(S) Kevin Ka-Wang Wang (Gainesville, Florida);  Zhihui Yang (Gainesville, Florida);  Ahmed Moghieb (Richland, Washington);  Richard Rubenstein (Staten Island, New York)
ABSTRACT Proteins that are differentially expressed or elevated in tissue and biofluids after central nervous system injuries are described. Elevated or reduced levels of the proteins, alone or in various combinations or ratios, can be used to assess severity of central nervous system injury (CNS injury) including traumatic brain injury (TBI), traumatic spinal cord injury (SCI) and chronic traumatic encephalopathy (CTE). Time course measurements post CNS-injury of these proteins can be used to monitor progress or recovery over periods up to several months. Differentiation of acute, subacute and chronic injury can be diagnosed by comparing the protein levels in CNS-injury patients at days 1-3, day 4-10 with levels at day 30-180 in comparison with normal controls.
FILED Wednesday, April 08, 2015
APPL NO 15/308934
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 33/6896 (20130101) Original (OR) Class
G01N 2800/28 (20130101)
G01N 2800/40 (20130101)
G01N 2800/56 (20130101)
G01N 2800/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725141 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin J Taylor (Escondido, California);  Susan Anne Elizabeth Berggren (San Diego, California);  Anna Leese De Escobar (Encinitas, California)
ABSTRACT First and second superconductive sensors receive an electromagnetic signal. The first and second superconductive sensors are spaced apart such that there is a phase difference between the electromagnetic signal as received at the first and second superconductive sensors. The first and second superconductive sensors output respective first and second voltage signals corresponding to the electromagnetic signal as received by the first and second superconductive sensors. A nonlinear detector detects a voltage difference between the first and second voltage signals and provides an output signal representing the detected voltage difference. The output signal corresponds to the phase difference between the electromagnetic signal as received at the first and second superconductive sensors.
FILED Tuesday, July 31, 2018
APPL NO 16/050937
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/035 (20130101)
G01R 33/0094 (20130101)
G01R 33/0354 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/043 (20130101) Original (OR) Class
G01S 3/46 (20130101)
G01S 3/48 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/364 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725154 Cochenour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brandon Cochenour (Alexandria, Virginia);  Lila Rodgers (Fayetteville, New York);  Alan Edward Laux (Great Mills, Maryland);  Linda Mullen (Chesapeake Beach, Maryland)
ABSTRACT A method and system for imaging in degraded visual environments. The system includes a laser that is positioned to transmit a Gaussian beam toward a target object located within the degraded visual environment. An optical receiver is positioned to receive return signals. A helical phase element is positioned between the target object and the optical receiver. The return signals pass through the helical phase element. The helical phase element separates coherent and incoherent light by imparting orbital angular momentum on the coherent returns to form an optical vortex.
FILED Friday, March 16, 2018
APPL NO 15/923016
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/484 (20130101)
G01S 7/4808 (20130101) Original (OR) Class
G01S 7/4861 (20130101)
G01S 7/4865 (20130101)
G01S 17/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725171 Stanley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Byron McCall Stanley (Newton, Massachusetts);  Matthew Tyler Cornick (San Diego, California)
ABSTRACT A method and a surface penetrating radar (SPR) system for localization of a vehicle are disclosed. The method includes transmitting a radar signal having a first frequency into a subsurface region adjacent to a vehicle. A first set of SPR images of a first subsurface volume within the subsurface region is acquired and location data for the vehicle are determined from the first set of SPR images. A second radar signal having a frequency that is greater than the first frequency is transmitted into the subsurface region and a second set of SPR images of a second subsurface volume within the subsurface region is acquired. The second subsurface volume at least partially overlaps the first subsurface volume. Location data are determined from the second set of SPR images at a greater resolution than the location data determined from the first set of SPR images.
FILED Monday, December 04, 2017
APPL NO 15/830398
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/06 (20130101)
B60W 2552/00 (20200201)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/26 (20130101)
G01C 21/3602 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/411 (20130101)
G01S 13/87 (20130101)
G01S 13/89 (20130101)
G01S 13/862 (20130101)
G01S 13/865 (20130101)
G01S 13/867 (20130101)
G01S 13/872 (20130101)
G01S 13/885 (20130101) Original (OR) Class
G01S 13/951 (20130101)
G01S 2013/9327 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725175 Sahin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Cenk Sahin (Beavercreek, Ohio);  Justin G. Metcalf (Dayton, Ohio);  Braham Himed (Beavercreek, Ohio)
ABSTRACT A receiver method and apparatus provides a more efficient computation and application of optimal filters. Range and Doppler processing in the receiver are decoupled and, as a result, computational complexity required for both filter computation and filtering stages are significantly reduced. In one embodiment, a response to an emitted signal is demodulated and sampled to provide baseband samples. The response includes a component due to interaction of the emitted signal with a target, The baseband samples are filtered in a bank of N parallel range filters to provide N filter outputs for each of the baseband samples. For one or more Doppler phase shifts ϕ, a discrete Fourier transform of the N filter outputs is computed to produce Doppler components that may be analyzed to determine at least one of a presence, range and speed of the target.
FILED Tuesday, October 30, 2018
APPL NO 16/175199
ART UNIT 2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/282 (20130101)
G01S 7/52025 (20130101)
G01S 13/878 (20130101)
G01S 15/8979 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725192 Camp
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) James Thomas Camp (Colonial Beach, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) James Thomas Camp (Colonial Beach, Virginia)
ABSTRACT A passive magnetic flux detector (PMFD) is provided for indicating an ambient magnetic field. The PMFD includes a coil, a rectifier, and an indicator. The indicator is either a light emitting diode (LED), a piezoelectric speaker or both.
FILED Wednesday, October 10, 2018
APPL NO 16/155934
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/02 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/10 (20130101) Original (OR) Class

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 3/10 (20130101)
G08B 5/36 (20130101)
G08B 21/182 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725280 Brady et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) David Jones Brady (Durham, North Carolina);  Jungsang Kim (Chapel Hill, North Carolina);  Daniel Marks (Durham, North Carolina);  Hui Seong Son (Durham, North Carolina)
ABSTRACT A multiscale telescopic imaging system is disclosed. The system includes an objective lens, having a wide field of view, which forms an intermediate image of a scene at a substantially spherical image surface. A plurality of microcameras in a microcamera array relay image portions of the intermediate image onto their respective focal-plane arrays, while simultaneously correcting at least one localized aberration in their respective image portions. The microcameras in the microcamera array are arranged such that the fields of view of adjacent microcameras overlap enabling field points of the intermediate image to be relayed by multiple microcameras. The microcamera array and objective lens are arranged such that light from the scene can reach the objective lens while mitigating deleterious effects such as obscuration and vignetting.
FILED Wednesday, April 19, 2017
APPL NO 15/491826
ART UNIT 2699 — Search and Capture Special Detail
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 13/06 (20130101)
G02B 13/16 (20130101)
G02B 23/12 (20130101) Original (OR) Class
G02B 27/0025 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 37/04 (20130101)

Pictorial Communication, e.g Television
H04N 5/247 (20130101)
H04N 5/2253 (20130101)
H04N 5/2254 (20130101)
H04N 5/2624 (20130101)
H04N 5/3415 (20130101)
H04N 5/3572 (20130101)
H04N 5/23212 (20130101)
H04N 5/23238 (20130101)
H04N 5/23296 (20130101)
H04N 9/045 (20130101)
H04N 13/204 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725290 Fan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jonathan A. Fan (Palo Alto, California);  David Sell (Stanford, California);  Jianji Yang (Menlo Park, California)
ABSTRACT Various embodiments are directed to an apparatus and methods of forming and/or using an apparatus comprising a plurality of device components. An example method includes geometrically optimizing a periodic or aperiodic device comprising a plurality of device components by optimizing a topology, for each device component, from a starting point to have particular optical properties for a particular optical response. Each device component includes a plurality of geometric structures. The optimization includes selecting the starting point for a continuous profile to have the particular optical properties for the particular optical response, iteratively converging the continuous profile to a discrete profile, and, while iteratively converging to the discrete profile, adjusting edges between boundaries of the device components by accounting for fabrication constraints.
FILED Monday, May 01, 2017
APPL NO 15/583827
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/18 (20130101)
G02B 27/0012 (20130101) Original (OR) Class
G02B 2005/1804 (20130101)
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725897 Staples et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Securboration, Inc. (Melbourne, Florida)
ASSIGNEE(S) Securboration, Inc. (Melbourne, Florida)
INVENTOR(S) Jacob A. Staples (Hooksett, New Hampshire);  Lee Krause (Indialtantic, Florida);  James B. Schneider (Melbourne, Florida);  Adam K. Kavanaugh (Orlando, Florida)
ABSTRACT Systems, methods, and apparatus for automatically parallelizing code segments are provided. For example, an environment includes a profiling agent, a parallelization agent, and a verification agent. The profiling agent executes a code segment and generates a profile of the executed code segment. The parallelization agent analyzes the code segment to determine whether a parallelizable portion is present in the code segment. When a parallelizable portion is present, the parallelization agent determines, based on the profile of the executed code segment, whether to parallelize the parallelizable portion of the code segment. If it is determined to parallelize the parallelizable portion of the code segment, the parallelization agent automatically parallelizes the parallelizable portion of the code segment. The verification agent verifies the functionality and/or correctness of the parallelized code segment.
FILED Wednesday, May 03, 2017
APPL NO 15/585516
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/456 (20130101)
G06F 9/45516 (20130101)
G06F 11/3688 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726171 Sheldon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Jeremy Sheldon (Henrietta, New York);  David Kasper (Shelton, Connecticut);  Garrett Argenna (Rochester, New York)
ABSTRACT A system and method for determining a remaining useful life of a component, includes providing a usage and configuration information associated with the component, determining if a preexisting spall condition exists for the component, executing a spall initiation model for the component if the preexisting spall condition does not exist, wherein the spall initiation model provides a spall initiation life associated with the component by analyzing the usage and configuration information, executing a spall propagation model for the component, wherein the spall propagation model provides a spall propagation life associated with the component by analyzing the usage and configuration information, and providing a remaining useful life by integrating the spall initiation life and the spall propagation life.
FILED Thursday, March 03, 2016
APPL NO 15/567498
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101)
B64D 2045/0085 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/0283 (20130101)

Electric Digital Data Processing
G06F 30/20 (20200101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/20 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/0808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726337 Thibeault et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Corey M. Thibeault (Valley Village, California);  Narayan Srinivasa (Oak Park, California)
ABSTRACT In a method for emulation of neuromorphic hardware on a computer processor, the neuromorphic hardware including computing circuits, the computing circuits including neurons and synapses connecting the neurons, the neurons being configured to communicate to each other through the synapses via spikes, the computing circuits being configured to execute in parallel in increments of time, the method includes, for each said time increment, emulating processing of the synapses, emulating processing of the neurons, and recording by the processor the next ones of the spikes for a subset of the neurons on a non-transitory physical medium. The processing of the synapses includes receiving previous ones of the spikes at presynaptic ends of the synapses, and transmitting the received previous ones of the spikes to postsynaptic ends of the synapses. The processing of the neurons includes receiving current ones of the spikes and generating next ones of the spikes.
FILED Friday, April 29, 2016
APPL NO 15/143466
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726643 Palmer
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S) SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S) Carl Palmer (Pittsford, New York)
ABSTRACT A corrosion management method is provided and includes storing an asset fleet at a location, generating a corrosion rate stressor by reference to models for any component of an asset of the asset fleet corresponding to the location and storage practice of the asset, predicting an accumulated corrosion stressor severity from the generated corrosion rate stressor, measuring an actual corrosion rate stressor at the location and revising the models in accordance with a difference between the predicted accumulated corrosion stressor severity and the measured actual corrosion rate stressor.
FILED Wednesday, March 30, 2016
APPL NO 15/571425
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 2045/0085 (20130101)

Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 5/60 (20170101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 17/00 (20130101)
G01N 17/006 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/006 (20130101)
G07C 5/0808 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726708 Pace
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Phillip E. Pace (San Juan Bautista, California)
ABSTRACT The invention automatically detects a gunshot at a plurality of detection and response nodes distributed in an area, determines the location of the active shooter, and deploys a suppression response to the location of the active shooter from each of the plurality of detection and response nodes to prevent the active shooter from firing further gunshots.
FILED Friday, May 24, 2019
APPL NO 16/421951
ART UNIT 2685 — Selective Communication
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00771 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 13/1672 (20130101)
G08B 13/19608 (20130101)
G08B 13/19645 (20130101)
G08B 25/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726908 Jeloka et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Arm Limited (Cambridge, United Kingdom)
ASSIGNEE(S) Arm Limited (Cambridge, United Kingdom)
INVENTOR(S) Supreet Jeloka (Austin, Texas);  Pranay Prabhat (Cambridge, United Kingdom);  James Edward Myers (Bottisham, United Kingdom)
ABSTRACT Various implementations described herein refer to an integrated circuit having a memory structure with an array of bitcells accessible via wordlines arranged in rows and bitlines arranged in columns. The integrated circuit may include source lines coupled to the bitcells. The integrated circuit may include source line drivers coupled between the wordlines and the source lines, and the source line drivers may allow the source lines to be used as switched source lines.
FILED Tuesday, August 21, 2018
APPL NO 16/107707
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 5/063 (20130101)
G11C 7/12 (20130101)
G11C 7/18 (20130101)
G11C 8/08 (20130101)
G11C 8/14 (20130101)
G11C 8/16 (20130101)
G11C 11/418 (20130101) Original (OR) Class
G11C 11/4091 (20130101)
G11C 16/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726943 Stojadinovic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
APPLICANT(S) Alexander Stojadinovic (Chevy Chase, Maryland);  Eric Elster (Kensington, Maryland);  Doug K. Tadaki (Frederick, Maryland);  John S. Eberhardt, III (Washington, District of Columbia);  Trevor Brown (Washington, District of Columbia);  Thomas A. Davis (Oak Hill, Virginia);  Jonathan Forsberg (Kensington, Maryland);  Jason Hawksworth (Silver Spring, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia);  THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland);  DECISIONQ CORPORATION (Arlington, Virginia)
INVENTOR(S) Alexander Stojadinovic (Chevy Chase, Maryland);  Eric Elster (Kensington, Maryland);  Doug K. Tadaki (Frederick, Maryland);  John S. Eberhardt, III (Washington, District of Columbia);  Trevor Brown (Washington, District of Columbia);  Thomas A. Davis (Oak Hill, Virginia);  Jonathan Forsberg (Kensington, Maryland);  Jason Hawksworth (Silver Spring, Maryland)
ABSTRACT An embodiment of the invention provides a method for determining a patient-specific probability of disease. The method collects clinical parameters from a plurality of patients to create a training database. A fully unsupervised Bayesian Belief Network model is created using data from the training database; and, the fully unsupervised Bayesian Belief Network is validated. Clinical parameters are collected from an individual patient; and, such clinical parameters are input into the fully unsupervised Bayesian Belief Network model via a graphical user interface. The patient-specific probability of the healing rate of an acute traumatic wound is output from the fully unsupervised Bayesian Belief Network model and sent to the graphical user interface for use by a clinician in pre-operative planning. The fully unsupervised Bayesian Belief Network model is updated using the clinical parameters from the individual patient and the patient-specific probability of the healing rate of an acute traumatic wound.
FILED Friday, April 08, 2011
APPL NO 13/083090
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 40/00 (20190201) Original (OR) Class
G16B 50/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726979 Liu
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) J. Ping Liu (Colleyville, Texas)
ABSTRACT The present invention relates to bulk magnetic nanocomposites and methods of making bulk magnetic nanocomposites.
FILED Thursday, January 07, 2016
APPL NO 14/989862
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0003 (20130101)
B22F 1/0018 (20130101)
B22F 1/0025 (20130101)
B22F 3/02 (20130101)
B22F 9/04 (20130101)
B22F 2009/041 (20130101)
B22F 2009/043 (20130101)
B22F 2301/45 (20130101)
B22F 2301/355 (20130101)
B22F 2304/05 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)
B82Y 30/00 (20130101)

Alloys
C22C 1/05 (20130101)
C22C 1/0441 (20130101)
C22C 28/00 (20130101)
C22C 2202/02 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/14 (20130101)
H01F 1/0556 (20130101) Original (OR) Class
H01F 1/0557 (20130101)
H01F 1/0579 (20130101)
H01F 41/0266 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727156 Cai et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California)
ASSIGNEE(S) TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California)
INVENTOR(S) Steve Qingjun Cai (Newbury Park, California);  Chung-Lung Chen (Thousand Oaks, California);  Chialun Tsai (Thousand Oaks, California)
ABSTRACT A system and method is disclosed for fabricating a heat spreader system, including providing a plurality of bottom microporous wicks recessed in a bottom substrate, bonding a center substrate to the bottom substrate, and bonding a top substrate having a top chamber portion to the center substrate to establish a first vapor chamber with said plurality of bottom microporous wicks.
FILED Tuesday, March 08, 2016
APPL NO 15/064304
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/26 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/046 (20130101)
F28D 15/0266 (20130101)
F28D 15/0283 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 21/04 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4882 (20130101)
H01L 23/427 (20130101) Original (OR) Class
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/22 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49352 (20150115)
Y10T 29/49353 (20150115)
Y10T 156/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727158 Brunschwiler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Thomas J. Brunschwiler (Thalwil, Switzerland);  Timothy J. Chainer (Putnam Valley, New York);  Evan G. Colgan (Montvale, New Jersey);  Arvind Raj Mahankali Sridhar (Zurich, Switzerland);  Chin Lee Ong (Horgen, Switzerland);  Pritish R. Parida (Stamford, Connecticut);  Gerd Schlottig (Uitikon, Switzerland);  Mark D. Schultz (Ossining, New York);  Joel A. Silberman (Somers, New York)
ABSTRACT A structure for cooling an integrated circuit. The structure may include; an interposer cold plate having at least two expanding channels, each expanding channel having a flow direction from a channel inlet to a channel outlet, the flow direction having different directions for at least two of the at least two expanding channels, the channel inlet having an inlet width and the channel outlet having an outlet width, wherein the inlet width is less than the outlet width.
FILED Wednesday, November 20, 2019
APPL NO 16/689445
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4871 (20130101)
H01L 23/427 (20130101) Original (OR) Class
H01L 23/473 (20130101)
H01L 24/16 (20130101)
H01L 24/17 (20130101)
H01L 24/73 (20130101)
H01L 25/0657 (20130101)
H01L 2224/16145 (20130101)
H01L 2224/16227 (20130101)
H01L 2224/17181 (20130101)
H01L 2224/32225 (20130101)
H01L 2224/32245 (20130101)
H01L 2224/73253 (20130101)
H01L 2225/06513 (20130101)
H01L 2225/06517 (20130101)
H01L 2225/06565 (20130101)
H01L 2225/06589 (20130101)
H01L 2924/15311 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727159 Brunschwiler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporatin (Armonk, New York)
INVENTOR(S) Thomas J. Brunschwiler (Thalwil, Switzerland);  Timothy J. Chainer (Putnam Valley, New York);  Evan G. Colgan (Montvale, New Jersey);  Arvind Raj Mahankali Sridhar (Zurich, Switzerland);  Chin Lee Ong (Horgen, Switzerland);  Pritish R. Parida (Stamford, Connecticut);  Gerd Schlottig (Uitikon, Switzerland);  Mark D. Schultz (Ossining, New York);  Joel A. Silberman (Somers, New York)
ABSTRACT A structure for cooling an integrated circuit. The structure may include; an interposer cold plate having at least two expanding channels, each expanding channel having a flow direction from a channel inlet to a channel outlet, the flow direction having different directions for at least two of the at least two expanding channels, the channel inlet having an inlet width and the channel outlet having an outlet width, wherein the inlet width is less than the outlet width.
FILED Friday, December 06, 2019
APPL NO 16/705278
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4871 (20130101)
H01L 23/427 (20130101) Original (OR) Class
H01L 23/473 (20130101)
H01L 24/16 (20130101)
H01L 24/17 (20130101)
H01L 24/73 (20130101)
H01L 25/0657 (20130101)
H01L 2224/16145 (20130101)
H01L 2224/16227 (20130101)
H01L 2224/17181 (20130101)
H01L 2224/32225 (20130101)
H01L 2224/32245 (20130101)
H01L 2224/73253 (20130101)
H01L 2225/06513 (20130101)
H01L 2225/06517 (20130101)
H01L 2225/06565 (20130101)
H01L 2225/06589 (20130101)
H01L 2924/15311 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727394 Bulsara et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California)
ASSIGNEE(S) United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Adi R. Bulsara (San Diego, California);  Bruno Ando (Catania, Italy);  Salvatore Baglio (Catania, Italy);  Vincenzo Marletta (Catania, Italy);  Antonio Pistorio (Catania, Italy)
ABSTRACT A system that may be used for energy harvesting includes a flexible beam secured between a first support and a second support. The supports are spaced apart at a distance less than a length of the flexible beam such that the beam is buckled. Responsive to external vibrations the flexible beam switches between a first position and a second position. A magnetic proof mass is coupled to the flexible beam at the beam's midpoint. At least one permanent magnet is positioned proximate to the magnetic proof mass and has the same polarity. The permanent magnet is positioned to expose the magnetic proof mass to a repulsive force when the magnetic proof mass is located at both the first position and the second position. Piezoelectric transducers are located above and below the first and second positions of the flexible beam to harvest energy.
FILED Tuesday, September 05, 2017
APPL NO 15/695815
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/08 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/053 (20130101)
H01F 7/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/1134 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 2/186 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727573 Merulla
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Emanuel Merulla (Bel Air, Maryland)
ABSTRACT Various embodiments are described that relate to an antenna. In one embodiment, the antenna can be a low profile, multi-band (e.g., dual band), emulated GPS constellation antenna. In one embodiment, the antenna can form a cube with two open sides and four circuit board sides. The four circuit boards can include a first hardware portion that allows functioning in a higher frequency band and a second hardware portion that allows functioning in a lower frequency band.
FILED Friday, March 24, 2017
APPL NO 15/468146
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/38 (20130101) Original (OR) Class
H01Q 5/335 (20150115)
H01Q 9/27 (20130101)
H01Q 21/205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727641 Reeves-Hall
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Peter C Reeves-Hall (Northbridge, Massachusetts)
ABSTRACT Herein is provided a fiber length including a doped fiber core extending over the fiber length. First and second cladding regions radially surround the core. At least one pump light input site is arranged to accept input pump light into the first cladding region. A low-absorption length over which the first cladding region has a first cross-sectional geometry produces a first level of absorption of input pump light from the first cladding region to the core, extending from a pump light input site for an extent over which the doped core can absorb at least about 10% of input pump light from the first cladding region. A high-absorption section over which the first cladding region has a second cross-sectional geometry produces a second level of absorption of input pump light from the first cladding region to the core, greater than the first level of absorption of input pump light.
FILED Thursday, January 18, 2018
APPL NO 15/874748
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/06754 (20130101)
H01S 3/10013 (20190801) Original (OR) Class
H01S 3/13017 (20190801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727765 Jean et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Daniel Louis Jean (Odenton, Maryland);  Ezra Chen (Bowie, Maryland);  Troy Caruso (Sterling Heights, Michigan);  Andrew Jen (Alexandria, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Daniel Louis Jean (Odenton, Maryland);  Ezra Chen (Bowie, Maryland);  Troy Caruso (Sterling Heights, Michigan);  Andrew Jen (Alexandria, Virginia)
ABSTRACT The friction driven linear motor includes a slide element with a portion with a pair of parallel straight sides. The slide element is contiguous with a zig-zag spring-like element, which is contiguous with an anchor block, which is contiguous with a MEMS substrate. The zig-zag spring-like element deforms as the slide element moves away from the anchor block. There are opposing pairs of v-beam thermal actuators. Each actuator includes a projecting cantilever beam with an end tip cycled to impinge, angularly, the slide element and extend, therein frictionally pushing the slide. A modulating current ohmically cycles the actuator from retraction to braking to pushing. At high frequencies the cantilever beam never fully retracts. The entire linear motor is composed of and is etched on a MEMS substrate.
FILED Tuesday, June 27, 2017
APPL NO 15/731539
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electric Machines Not Otherwise Provided for
H02N 10/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727804 Gong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Songbin Gong (Champaign, Illinois);  Ruochen Lu (Champaign, Illinois);  Tomas Manzaneque Garcia (Champaign, Illinois);  Cheng Tu (Urbana, Illinois);  Daniel Shoemaker (Urbana, Illinois);  Chengxi Zhao (Urbana, Illinois)
ABSTRACT An integrated circuit is a layered device, on a semiconductor substrate, which contains metal electrodes that sandwich a piezoelectric layer, followed by a magnetostrictive layer and a metal coil. The metal electrodes define an electrical port across which to receive an alternating current (AC) voltage, which is applied across the piezoelectric layer to cause a time-varying strain in the piezoelectric layer. The magnetostrictive layer is to translate the time-varying strain, received by way of a vibration mode from interaction with the piezoelectric layer, into a time-varying electromagnetic field. The metal coil, disposed on the magnetostrictive layer, includes a magnetic port at which to induce a current based on exposure to the time-varying electromagnetic field generated by the magnetostrictive layer.
FILED Monday, October 23, 2017
APPL NO 15/790999
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/20 (20130101)
H01F 10/126 (20130101)
H01F 10/265 (20130101)
H01F 21/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/00 (20130101)

Modulation
H03C 1/46 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 2/001 (20130101)
H03H 7/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727847 Ferriss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Mark Ferriss (Tarrytown, New York);  Bodhisatwa Sadhu (Peekskill, New York);  Wooram Lee (Briarcliff Manor, New York);  Daniel Friedman (Sleepy Hollow, New York)
ABSTRACT A capacitance of a digitally controlled circuit coupled to a first multiplexer (MUX) having a first switch coupled between a first input and a first output, a first pullup device coupled between VDD and the first output, and a first pulldown device coupled between the first output and VSS is controlled. For falling slope of the first output, in a first phase, which is before the falling slope of the first output, turning ON the first switch, and turning OFF the first pullup device. In a second phase, which is during the falling slope of the first output, the first input is coupled to an output of a digital to analog converter coupled to the MUX. In a third phase, which is after the falling slope of the first output, the first switch is turned OFF and the first pulldown device is turned ON.
FILED Thursday, February 07, 2019
APPL NO 16/270564
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 5/124 (20130101)
H03B 5/1206 (20130101)
H03B 5/1265 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/102 (20130101)
H03L 7/0991 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727886 Pister et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kristofer S. J. Pister (Orinda, California);  Osama Ullah Khan (Berkeley, California);  Bradley Wheeler (Berkeley, California);  David C. Burnett (Berkeley, California)
ABSTRACT A crystal-free radio includes an antenna; a receiver configured to communicate with the antenna; a local radio frequency (RF) oscillator configured to communicate with the receiver; and a clock circuit configured to communicate with the receiver and the local RF oscillator, the clock circuit having an electronic circuit oscillator. The local RF oscillator is a free-running oscillator. The clock circuit is configured to receive a calibration signal via a wireless network and calibrate the electronic circuit oscillator based on the received calibration signal, and the clock circuit is a crystal-free clock circuit.
FILED Monday, May 08, 2017
APPL NO 16/099992
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Pulse Technique
H03K 3/0315 (20130101)

Transmission
H04B 1/26 (20130101) Original (OR) Class
H04B 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727947 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT The present invention reduces the level of optical reflections created in a photonic integrated circuit (PIC) going back into an integrated laser through Reflection Engineering; optimizing the phase/timing and position of optical reflections inherent to a PIC design while adding engineered reflections to the PIC to allow inherent reflections to be reduced or eliminated. The Wavelength Division Multiplexed (WDM) geometric optical isolator of the present invention combines an array of closely spaced WDM lasers with an array of modulators in a novel geometry in order to provide effective optical isolation of the lasers.
FILED Wednesday, April 24, 2019
APPL NO 16/393842
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101)
H04B 10/50 (20130101)
H04B 10/516 (20130101)
H04B 10/25759 (20130101) Original (OR) Class
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728017 Bent et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Graham A. Bent (Hursley, United Kingdom);  Flavio A. Bergamaschi (Southampton, United Kingdom);  Jack L. H. Crawford (Barking, United Kingdom);  Hamish C. Hunt (Ashford, United Kingdom)
ABSTRACT In a fully homomorphic encryption scheme, a method is provided for performing a homomorphic operation on a data set by applying an encrypted operand supplied as a ciphertext. A data set containing ‘i’ library vectors, each with ‘j’ coefficients is subjected to a pivot operation such that each set of common ‘j’ coefficients is stored in respective library ciphertexts. A query ciphertext containing a query vector is then subjected to a homomorphic pivot operation to separate out its ‘j’ coefficients into respective pivoted query ciphertexts. A more efficient homomorphic computation can then be carried out between the ciphertexts of the pivoted forms of the query and library vectors so as to compute an encrypted set of vector differences between the query vector and each of the library vectors.
FILED Friday, November 03, 2017
APPL NO 15/802879
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)
G06F 21/602 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/008 (20130101) Original (OR) Class
H04L 9/3093 (20130101)
H04L 63/0428 (20130101)
H04L 2209/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728040 Seibert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Tai Seibert (San Diego, California);  Haw-minn Lu (San Diego, California)
ASSIGNEE(S)
INVENTOR(S) Tai Seibert (San Diego, California);  Haw-minn Lu (San Diego, California)
ABSTRACT Various embodiments of the present disclosure provide a system and method for detecting network connections having a plurality of interconnected network nodes; a connection-based behavioral anomaly detection device (“CBAD”) connected to one of the plurality of network nodes such that the CBAD may observe data traffic flowing through at least one node of the plurality of network nodes; an application loaded onto a first node of the plurality of network nodes, the application initializing a connection from the first node to a second node of the plurality of network nodes; and a computer-readable storage device communicatively connected to the CBAD; wherein the application transmits a plurality of data packets from the first node to the second node of the plurality of network nodes; the CBAD observes at least one of the plurality of data packets exchanged between the first node and the second node; the CBAD extrapolates packet information from at least one of the plurality of data packets observed; and the extrapolated packet information is stored on the storage device. The present disclosure also provides a method and system for detecting connections within a network including observing a plurality of data packets transferred from an application loaded onto a first node to a second node of the plurality of interconnected network nodes; extrapolating packet information; and comparing the extrapolated data packets against historical data; wherein the CBAD is connected to at least one of the nodes; and the application initialized a connection with the second node.
FILED Friday, September 14, 2018
APPL NO 16/132273
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3247 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728106 Hartley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Layered Sensing Exploitation Division (AFRL/RYA)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) Architecture Technology Corporation (Eden Prairie, Minnesota)
INVENTOR(S) Timothy E. Hartley (Eden Prairie, Minnesota);  Ranga S. Ramanujan (Medina, Minnesota)
ABSTRACT A method of managing a plurality of client nodes in a network is disclosed. A plurality of domains is provided in the network, each domain isolating data from other domains. A plurality of applications is also provided, each application of the plurality of applications allowed to operate in one or more of the plurality of domains. Each of the plurality of client nodes is allowed to operate in one or more of the plurality of domains. The method includes assigning the plurality of applications to the plurality of client nodes, such that each application of the plurality of applications is assigned to a client node that is allowed to operate in a domain that the application is allowed to operate in.
FILED Monday, May 01, 2017
APPL NO 15/583711
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 9/45558 (20130101)
G06F 2009/45579 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/4641 (20130101)
H04L 41/20 (20130101) Original (OR) Class
H04L 45/74 (20130101)
H04L 63/0428 (20130101)
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728149 Ramanujan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Architecture Technology Corporation (Eden Prairie, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Ranga S. Ramanujan (Medina, Minnesota);  Benjamin L. Burnett (Prior Lake, Minnesota);  Barry A. Trent (Chanhassen, Minnesota);  Jafar Al-Gharaibeh (Bloomington, Minnesota)
ABSTRACT A method of routing a packet from a routing device includes receiving a first packet having a first header and a first data field. The first header has a final destination corresponding to a destination device communicatively coupled to the routing device via at least two parallel network links. A second packet having a second header and a second data field is sent over the first network link. The second data field is identical to the first data field. A destination address in the second header corresponds to a device on a first of the parallel network links. A third packet having a third header and a third data field is sent over the second network link. The third data field is identical to the first data field. a destination address in the third header corresponds to a device on a second of the parallel network links.
FILED Friday, May 12, 2017
APPL NO 15/593883
ART UNIT 2466 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/24 (20130101)
H04L 45/56 (20130101)
H04L 45/745 (20130101) Original (OR) Class
H04L 49/109 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728231 Khazan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Roger I. Khazan (Arlington, Massachusetts);  Joshua Kramer (Burlington, Massachusetts);  Daniil M. Utin (Waban, Massachusetts);  Mankuan Michael Vai (Sudbury, Massachusetts);  David Whelihan (Framingham, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Roger I. Khazan (Arlington, Massachusetts);  Joshua Kramer (Burlington, Massachusetts);  Daniil M. Utin (Waban, Massachusetts);  Mankuan Michael Vai (Sudbury, Massachusetts);  David Whelihan (Framingham, Massachusetts)
ABSTRACT A circuit for secure operation includes a plurality of mutually exclusive circuit zones including a first circuit zone having a first level of security and a second circuit zone having a second level of security less than the first level of security and one or more gate circuits each providing limited transfer of data between the circuit zones, the gate circuits providing all data connectivity between the first circuit zone and the second circuit zone and statically configured to prevent unmodified transfer of data from the first circuit zone to the second circuit zone.
FILED Tuesday, July 09, 2013
APPL NO 13/937884
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/60 (20130101)
G06F 21/602 (20130101)
G06F 21/606 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/0819 (20130101)
H04L 9/0894 (20130101)
H04L 63/20 (20130101)
H04L 63/061 (20130101) Original (OR) Class
H04L 63/126 (20130101)
H04L 63/0428 (20130101)
H04L 2209/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10729045 Jones
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Daniel P. Jones (Pinellas Park, Florida)
ABSTRACT A wireless communication electronic assembly can include a plurality of integrated modules each having a ground plate interfaced to each other and defining a shielding plane. Each ground plate can have a left edge and a right edge opposite each other. A plurality of wireless communication devices can be positioned on one side of the shielding plane, and a plurality of electronic devices can be positioned on the other side of the shielding plane. One or more electromagnetic shielding elements, such as gasket(s), channel strip(s), stamping element(s), etc. can be disposed between the left edge and the right edge of adjacent ground plates to electromagnetically shield the plurality of electronic devices from the plurality of wireless communication devices. The left and right edges can be recessed or offset on one side of the shielding plane. Rows and columns of integrated modules can be interfaced about a plurality of electromagnetic shielding elements. A method of installing and replacing integrated modules of an antenna array.
FILED Tuesday, November 19, 2019
APPL NO 16/689005
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/1656 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/526 (20130101)
H01Q 21/061 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 9/0081 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US D891413 McIntire et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) John P. McIntire (Dayton, Ohio);  KelseyLee Schafer (Beavercreek, Ohio);  Duy K Nguyen (Dayton, Ohio)
ABSTRACT
FILED Monday, November 21, 2016
APPL NO 29/585149
ART UNIT 2922 — Design
CURRENT CPC
Recording, communication, or information retrieval equipment
D14/250
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10722812 Baxter et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Larry Baxter (Orem, Utah);  Kyler Stitt (Lindon, Utah);  Aaron Sayre (Spanish Fork, Utah);  Christopher Hoeger (Provo, Utah)
ASSIGNEE(S) Hall Labs LLC (Provo, Utah)
INVENTOR(S) Larry Baxter (Orem, Utah);  Kyler Stitt (Lindon, Utah);  Aaron Sayre (Spanish Fork, Utah);  Christopher Hoeger (Provo, Utah)
ABSTRACT A process to prevent fouling using a desublimating heat exchanger is disclosed. An outlet stream from the desublimating heat exchanger may be split into a plurality of parallel streams. The parallel streams may be sent through a plurality of discrete unit operations, and the unit operations may change the temperature of at least one of the parallel streams. Parallel streams of differing temperature may emerge from the unit operations. The parallel streams which are of a similar temperature may be mixed to form a warm stream and a cool stream. The warm stream and the cool stream may be sent to a mixing chamber. A mixed stream of substantially uniform temperature may emerge from the mixing chamber, and the mixed stream may be recycled back to the desublimating heat exchanger. The mixing chamber may be separate from the desublimating heat exchanger, or the parallel streams of differing temperature may be mixed in the desublimating heat exchanger.
FILED Monday, April 17, 2017
APPL NO 15/488784
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Separation
B01D 5/00 (20130101)
B01D 7/00 (20130101) Original (OR) Class
B01D 8/00 (20130101)
B01D 9/00 (20130101)
B01D 9/0009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722837 Koech et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Phillip K. Koech (Richland, Washington);  Deepika Malhotra (Richland, Washington);  David J. Heldebrant (Richland, Washington);  Vassiliki-Alexandra Glezakou (Richland, Washington);  Roger J. Rousseau (Richland, Washington);  David C. Cantu (Reno, Nevada)
ABSTRACT A class of water lean, organic solvents that can bind with various acid gasses to form acid gas bound molecules having a high degree of intramolecular hydrogen bonding which enables their use as regenerable solvents for acid gas capture. Unlike the other devices described in the prior art, the present invention takes advantage of shortened distances between the portions of the molecule that form hydrogen bonds within the structures when loaded with an acid gas so as to create a molecule with a higher internal bonding affinity and a reduced proclivity for agglomeration with other molecules.
FILED Thursday, August 15, 2019
APPL NO 16/541691
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/1425 (20130101) Original (OR) Class
B01D 53/1456 (20130101)
B01D 53/1493 (20130101)
B01D 2252/2041 (20130101)
B01D 2252/20426 (20130101)
B01D 2252/20431 (20130101)
B01D 2252/20457 (20130101)
B01D 2257/302 (20130101)
B01D 2257/308 (20130101)
B01D 2257/504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722863 Long et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Office of Science (DOE-SC)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Jeffrey R. Long (Oakland, California);  Thomas M. McDonald (Berkeley, California)
ABSTRACT A system and method for acid gas separations using porous frameworks of metal atoms coordinatively bound to polytopic linkers that are functionalized with basic nitrogen ligands that expose nitrogen atoms to the pore volumes forming adsorption sites. Adjacent basic nitrogen ligands on the metal-organic framework can form an ammonium from one ligand and a carbamate from the other. The formation of one ammonium carbamate pair influences the formation of ammonium carbamate on adjacent adsorption sites. Adsorption of acid gas at the adsorption sites form covalently linked aggregates of more than one ammonium carbamate ion pair. The acid gas adsorption isotherm can be tuned to match the step position with the partial pressure of acid gas in the gas mixture stream through manipulation of the metal-ligand bond strength by selection of the ligand, metal and polytopic linker materials.
FILED Tuesday, October 18, 2016
APPL NO 15/297114
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 53/40 (20130101)
B01D 53/62 (20130101)
B01D 2253/204 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101) Original (OR) Class
B01J 20/3085 (20130101)
B01J 20/3425 (20130101)
B01J 20/3483 (20130101)
B01J 20/28057 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/04 (20130101)
Y02C 10/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722922 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UHV Technologies, Inc. (Fort Worth, Texas)
ASSIGNEE(S) UHV Technologies, Inc. (Fort Worth, Texas)
INVENTOR(S) Nalin Kumar (Fort Worth, Texas);  Manuel Gerardo Garcia, Jr. (Lexington, Kentucky);  Isha Kamleshbhai Maun (Arlington, Texas)
ABSTRACT A material sorting system sorts materials utilizing a vision system that implements a machine learning system in order to identify or classify each of the materials, which are then sorted into separate groups based on such an identification or classification determining that the materials are composed of either wrought aluminum or cast aluminum.
FILED Thursday, April 04, 2019
APPL NO 16/375675
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/04 (20130101)
B07C 5/34 (20130101)
B07C 5/342 (20130101)
B07C 5/3422 (20130101) Original (OR) Class
B07C 2501/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723079 Messner
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Mark Christian Messner (Tracy, California)
ABSTRACT The apparatus generates slices of slender member structures for additive manufacturing of object using a processor having associated non-transitory memory. The memory is programmed to define a graph data structure for storing data representing a plurality of elongated struts each having a predefined spatial position and orientation relative to a three-dimensional reference frame. The memory is further programmed to define a slice data structure for storing data representing spaced apart and parallel two-dimensional slices each passing through the three-dimensional reference frame, the slice data structure storing for each slice a grid comprising a plurality of pixels, each pixel representing a binary state indicating whether material is or is not added in performing additive manufacturing of an object.
FILED Wednesday, August 23, 2017
APPL NO 15/683953
ART UNIT 2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/40 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/00 (20141201)
B33Y 50/02 (20141201)

Electric Digital Data Processing
G06F 30/17 (20200101)
G06F 30/23 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723671 Fan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Hongyou Fan (Albuquerque, New Mexico);  Kaifu Bian (Beaverton, Oregon);  David Rosenberg (Albuquerque, New Mexico);  Leanne Julia Alarid (Albuquerque, New Mexico)
ABSTRACT A new, rapid and inexpensive synthesis method for monodispersed triaminotrinitrobenzene (TATB) microparticles based on micelle-confined precipitation that enables control of microscopic morphology. The morphology of the TATB microparticles can be tuned between quasi-spherical and faceted by controlling the speed of recrystallization. The method enables improved performance and production consistency of TATB explosives for military grade explosives and propellants
FILED Tuesday, July 24, 2018
APPL NO 16/043800
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0033 (20130101)
C06B 25/04 (20130101)
C06B 45/02 (20130101)
C06B 45/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724091 Meagher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Robert Meagher (Mountain House, California);  Chung-Yan Koh (Dublin, California);  Yooli Kim Light (Pleasanton, California);  Cameron Scott Ball (Sunnyvale, California)
ABSTRACT The present invention relates to probes and primers beneficial for conducting amplification assays, such as those including loop-mediated isothermal amplification reactions. Also described herein are methods for detecting targets using such probes and/or primers.
FILED Wednesday, January 27, 2016
APPL NO 15/008285
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724120 Boyle et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Timothy J. Boyle (Albuquerque, New Mexico);  LaRico Juan Treadwell (Albuquerque, New Mexico)
ABSTRACT The ability to generate complex gallium alloys using metal amides, Ga(NR2)3 and M(NR2)n, is easily accomplished by heating the two metal amides in predetermined ratios. The product can be isolated as GaxMy where x and y can vary.
FILED Tuesday, August 21, 2018
APPL NO 16/107814
ART UNIT 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Production and Refining of Metals; Pretreatment of Raw Materials
C22B 58/00 (20130101) Original (OR) Class
C22B 59/00 (20130101)

Alloys
C22C 24/00 (20130101)
C22C 28/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724145 Subbaraman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Ram Subbaraman (Westmont, Illinois);  Vojislav Stamenkovic (Naperville, Illinois);  Nenad Markovic (Hinsdale, Illinois);  Dusan Tripkovic (Hinsdale, Illinois)
ABSTRACT Systems and methods for a hydrogen evolution reaction catalyst are provided. Electrode material includes a plurality of clusters. The electrode exhibits bifunctionality with respect to the hydrogen evolution reaction. The electrode with clusters exhibits improved performance with respect to the intrinsic material of the electrode absent the clusters.
FILED Friday, January 22, 2016
APPL NO 15/004737
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101)
C25B 9/06 (20130101)
C25B 11/02 (20130101)
C25B 11/0405 (20130101)
C25B 11/0415 (20130101)
C25B 11/0447 (20130101) Original (OR) Class
C25B 11/0452 (20130101)
C25B 11/0457 (20130101)
C25B 11/0478 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724441 Berry et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jonathan Dwight Berry (Simpsonville, South Carolina);  Michael John Hughes (Pittsburgh, Pennsylvania)
ABSTRACT An annular combustion system includes a fuel nozzle, a panel fuel injector including a fuel plenum and at least one premixing channel therein, an inner liner including an inner band radially spaced from an outer band and an inner flow annulus formed therebetween, and an outer liner radially spaced from the inner liner and comprising an inner band radially spaced from an outer band and an outer flow annulus formed therebetween. The fuel nozzle is positioned radially between the inner liner and the outer liner, and the panel fuel injector extends radially between the inner liner and the outer liner. At least one of the inner flow passage and the outer flow passage is in fluid communication with at least one of a premix air plenum, a cooling air cavity and a cooling air plenum defined within the panel fuel injector.
FILED Friday, February 24, 2017
APPL NO 15/442171
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 7/18 (20130101) Original (OR) Class
F02C 7/22 (20130101)
F02C 7/222 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/35 (20130101)
F05D 2260/201 (20130101)
F05D 2260/202 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
F23R 3/005 (20130101)
F23R 3/06 (20130101)
F23R 3/10 (20130101)
F23R 3/28 (20130101)
F23R 3/34 (20130101)
F23R 3/283 (20130101)
F23R 3/286 (20130101)
F23R 3/346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724744 Uselton
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Lennox Industries Inc. (Richardson, Texas)
ASSIGNEE(S) Lennox Industries Inc. (Richardson, Texas)
INVENTOR(S) Robert B. Uselton (Plano, Texas)
ABSTRACT An apparatus that includes a refrigeration circuit that includes an evaporator, a first condenser and a compressor. The apparatus includes a refrigerant-water heat exchanger that includes a second condenser fluidly coupled to the refrigeration circuit. A control valve is operatively connected to the refrigeration circuit to direct flow of refrigerant through at least one of the first condenser during a dehumidification mode and the second condenser during a water heating mode. A damper is disposed on an upwind side of the evaporator, the damper being operable to reduce airflow across the evaporator during a ventilation mode.
FILED Wednesday, September 21, 2016
APPL NO 15/271419
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor
F24D 11/0242 (20130101) Original (OR) Class
F24D 17/001 (20130101)
F24D 17/02 (20130101)
F24D 2200/22 (20130101)
F24D 2200/123 (20130101)

Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 3/14 (20130101)
F24F 11/0008 (20130101)
F24F 2003/1446 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 6/02 (20130101)
F25B 30/02 (20130101)
F25B 41/046 (20130101)
F25B 2339/047 (20130101)
F25B 2600/2507 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 10/70 (20130101)
Y02B 30/18 (20130101)
Y02B 30/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724809 Yang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado);  UNIVERSITY OF WYOMING (Laramie, Wyoming)
ASSIGNEE(S) The Regents of the University of Colorado, a Body Corporate (Denver, Colorado);  University of Wyoming (Laramie, Wyoming)
INVENTOR(S) Ronggui Yang (Boulder, Colorado);  Xiaobo Yin (Boulder, Colorado);  Gang Tan (Fort Collins, Colorado);  Dongliang Zhao (Boulder, Colorado);  Yaoguang Ma (Boulder, Colorado);  Yao Zhai (Boulder, Colorado)
ABSTRACT Polymer-based selective radiative cooling structures are provided which include a selectively emissive layer of a polymer or a polymer matrix composite material. Exemplary selective radiative cooling structures are in the form of a sheet, film or coating. Also provided are methods for removing heat from a body by selective thermal radiation using polymer-based selective radiative cooling structures.
FILED Monday, February 27, 2017
APPL NO 16/085429
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 17/10238 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/01 (20180101)
C08K 3/36 (20130101)
C08K 2201/005 (20130101)

Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 5/0092 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 23/003 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 20/00 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 13/18 (20130101) Original (OR) Class
F28F 2245/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724891 Baxter et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Larry Baxter (Orem, Utah);  Eric Mansfield (Spanish Fork, Utah);  Aaron Sayre (Spanish Fork, Utah);  David Frankman (Provo, Utah)
ASSIGNEE(S) Hall Labs LLC (Provo, Utah)
INVENTOR(S) Larry Baxter (Orem, Utah);  Eric Mansfield (Spanish Fork, Utah);  Aaron Sayre (Spanish Fork, Utah);  David Frankman (Provo, Utah)
ABSTRACT A vessel with a cavity for measuring level is disclosed. The vessel includes a differential pressure sensor having a first port and a second port, a reference tube that connects the first port of the differential pressure sensor to a bottom portion of the cavity, and an impulse tube that connects the second port of the differential pressure sensor to an impulse tube ending. At least a portion of the impulse tube extends through the cavity and ends at a fluid inlet. The fluid inlet is located at a level above the reference tube.
FILED Tuesday, April 17, 2018
APPL NO 15/955100
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 23/14 (20130101)
G01F 23/16 (20130101)
G01F 23/18 (20130101) Original (OR) Class
G01F 23/164 (20130101)
G01F 25/0061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724927 Hamann et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Hendrik F. Hamann (Yorktown Heights, New York);  Levente I. Klein (Tuckahoe, New York);  Dennis G. Manzer (Bedford Hills, New York);  Fernando J. Marianno (New York, New York)
ABSTRACT Systems for predicting a filter lifetime. A filter monitoring system includes a filter effectiveness history based on contaminant sensor information associated with a filter received from one or more contaminant sensors. A lifetime module is configured to determine a rate of filter consumption based on the filter effectiveness history and to determine a remaining filter lifetime based on the determined rate of filter consumption.
FILED Thursday, March 19, 2015
APPL NO 14/663070
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Separation
B01D 46/0086 (20130101)
B01D 46/429 (20130101)
B01D 46/442 (20130101)
B01D 2273/10 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 9/00 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 99/008 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 17/04 (20130101)
G01N 33/0004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724965 Sachs et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Emanuel M. Sachs (Newton, Massachusetts);  Tonio Buonassisi (Cambridge, Massachusetts);  Sarah Wieghold (Somerville, Massachusetts);  Zhe Liu (Xi'an, China PRC)
ABSTRACT Embodiments related to systems and methods of crack detection in wafers (e.g., silicon wafers for photovoltaics, photovoltaic devices including silicon wafers) are disclosed. In some embodiments, an apparatus may include a light source configured to illuminate a side of a wafer and a camera directed towards a first face of the wafer. In some embodiments, a long axis of a field of view of the camera may be angled relative to a propagation direction of the light source. In some embodiments, at least a portion of the field of view of the camera is offset from the path of propagation of light emitted from the light source through the wafer. In some embodiments, at least a portion of a light beam may be oriented at a positive non-zero angle relative to the first face of the wafer, and a dimension of the light beam normal to the first face of the wafer may be larger than a thickness of the wafer.
FILED Friday, February 08, 2019
APPL NO 16/271049
ART UNIT 2882 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/8806 (20130101)
G01N 21/9505 (20130101) Original (OR) Class
G01N 2201/06113 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/67288 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725053 Qian et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington);  University of Washington (Seattle, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington);  University of Washington (Seattle, Washington)
INVENTOR(S) Wei-Jun Qian (Richland, Washington);  Tujin Shi (Richland, Washington);  Alvin Y. Liu (Everett, Washington)
ABSTRACT Methods are provided for treating a subject with prostate cancer and/or diagnosing a subject at risk for prostate cancer, which can include measuring increased expression of at least two prostate cancer-related molecules in a sample obtained from a subject, including the prostate cancer-related molecules AGR2, AGR3, CRISP3, CCL3, CEACAM5, CEACAM6, IL24, MMP9, CXCL14, CD90, POSTN, and SFRP4. The methods can include administering at therapy to a subject with prostate cancer. Methods are provided for treating a subject with intermediate- or high-risk prostate cancer, which can include measuring increased expression of MMP9 in a sample obtained from a subject compared to a control representing expression of MMP9 expected in a sample from a subject who has low-risk prostate cancer.
FILED Tuesday, December 12, 2017
APPL NO 15/839635
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/37 (20130101)
C12Q 1/533 (20130101)

Enzymes
C12Y 304/24035 (20130101)
C12Y 503/04001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
G01N 33/6863 (20130101)
G01N 33/6869 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 33/57434 (20130101)
G01N 2333/47 (20130101)
G01N 2333/52 (20130101)
G01N 2333/54 (20130101)
G01N 2333/99 (20130101)
G01N 2333/70503 (20130101)
G01N 2333/70596 (20130101)
G01N 2333/96486 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725075 Williams et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington);  AMERICAN ELECTRIC POWER COMPANY INC. (Columbus, Ohio)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington);  American Electric Power Company, Inc. (Columbus, Ohio)
INVENTOR(S) Tess L. Williams (Seattle, Washington);  Kevin P. Schneider (Seattle, Washington);  Michael T. Campbell (Springdale, Arkansas);  Derek S. Lewellen (Tulsa, Oklahoma)
ABSTRACT A method of evaluating an optimization system is disclosed. The system is transitioned from an on state to an off state. Data is collected at time intervals for a time period before and after the system is transitioned from the on state to the off state. The transitioning occurs while a load of a particular type is active. In one embodiment, the optimization system is a Volt/VAR Optimization (VVO) system.
FILED Monday, September 16, 2019
APPL NO 16/572510
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 21/002 (20130101)
G01R 21/133 (20130101) Original (OR) Class
G01R 22/063 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 13/00 (20130101)

Selecting
H04Q 9/00 (20130101)
H04Q 2209/826 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725208 Alvine et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Kyle J. Alvine (Richland, Washington);  Bruce E. Bernacki (Kennewick, Washington)
ABSTRACT Conductive nanoshells are oriented so as to redirect incident radiation as a function of wavelength. Nanoshells can be formed on templates such as nanospheres or gratings and embedded in an elastomeric layer. In some examples, conductive nanoshells are coupled to a layer that is configured to unbuckle and buckle as a function of temperature, so that radiation in one or more wavelength ranges is directed differently at different temperatures. Building windows can include such layers to that infrared radiation is reflected on warm days and directed into a building on cool days. Such layers can also direct incident visible radiation to a room ceiling so as to enhance interior lighting.
FILED Thursday, June 20, 2013
APPL NO 13/923205
ART UNIT 2872 — Optics
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/24 (20130101)
E06B 9/264 (20130101)
E06B 2009/2417 (20130101)
E06B 2009/2643 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/005 (20130101)
G02B 1/007 (20130101)
G02B 1/10 (20130101) Original (OR) Class
G02B 1/14 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725209 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Baomin Wang (State College, Pennsylvania);  Noel C. Giebink (State College, Pennsylvania)
ABSTRACT A method for generating antireflective coatings for polymeric substrates using a deposition process and/or a dissolving process can provide a coating onto the outer surface of the substrate. Some embodiments can include a GLAD generated fluoropolymer coating or a co-evaporated fluoropolymer coating on a substrate that may achieve ultralow refractive index as well as improved adhesion and durability properties on polymeric substrates. In some embodiments, the deposition process is performed such that a fluoropolymer can be evaporated to form chain fragments of the fluoropolymer. The chain fragments diffused into the substrate can subsequently re-polymerize, interlocking with the polymer chains of the substrate. In some embodiments, the co-evaporation process can form a nanoporous polymer chain scaffold of the fluoropolymer, from which a sacrificial material can be dissolved out. The formed coating can be a multilayer or continuously-graded antireflective coating that has strong adhesion with the substrate.
FILED Tuesday, January 09, 2018
APPL NO 16/465641
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 127/12 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/12 (20130101)
G02B 1/111 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725245 Leigh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Kevin B. Leigh (Houston, Texas);  Nicolas G. McDonald (Ft. Collins, Colorado)
ABSTRACT A multi-port aggregated cable includes: a plurality of duplex optical fibers, each duplex optical fiber having a first end and a second end; a first optical interface attached to each of the duplex optical fibers at the first end thereof and defining multiple ports, one for each of the duplex optical fibers, the first optical interface aggregating the duplex optical fibers at the first end thereof; and a second optical interface attached to each of the duplex optical fibers at the second end thereof and defining multiple ports, one for each of the duplex optical fibers, the second optical interface aggregating the duplex optical fibers at the second end thereof.
FILED Sunday, December 16, 2018
APPL NO 16/221537
ART UNIT 2896 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/381 (20130101) Original (OR) Class
G02B 6/3897 (20130101)
G02B 6/4415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725360 Lukens et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Joseph M. Lukens (Knoxville, Tennessee);  Nicholas A. Peters (Knoxville, Tennessee);  Raphael C. Pooser (Knoxville, Tennessee)
ABSTRACT A nonlinear fiber interferometer is disclosed suitable for fiber sensor and other applications. A first nonlinear fiber section amplifies probe and conjugate sidebands of a pump through four-wave mixing. A second section introduces a phase shift to be measured, for example from a sensor. A third nonlinear fiber section amplifies with phase-sensitive gain to increase signal-to-noise ratio. Based on phase-sensitive output power of probe and/or conjugate components, the phase shift can be measured. Superior performance can be obtained by balancing gain between the (first and third) nonlinear sections. Non-fiber, for example photonic integrated circuit, embodiments are disclosed. Differential sensing, alternative detection schemes, sensing applications, associated methods, and other variations are disclosed.
FILED Friday, May 10, 2019
APPL NO 16/408945
ART UNIT 2874 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/39 (20130101) Original (OR) Class
G02F 1/3501 (20130101)
G02F 1/3544 (20130101)
G02F 2001/392 (20130101)
G02F 2001/3507 (20130101)
G02F 2203/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725670 Kotra et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S) Jagadish B. Kotra (Austin, Texas);  Karthik Rao (Austin, Texas);  Joseph L. Greathouse (Austin, Texas)
ABSTRACT A system including a stack of two or more layers of volatile memory, such as layers of a 3D stacked DRAM memory, places data in the stack based on a temperature or a refresh rate. When a threshold is exceeded, data are moved from a first region to a second region in the stack, the second region having one or both of a second temperature lower than a first temperature of the first region or a second refresh rate lower than a first refresh rate of the first region.
FILED Wednesday, August 01, 2018
APPL NO 16/052055
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Electric Digital Data Processing
G06F 3/0619 (20130101) Original (OR) Class
G06F 3/0634 (20130101)
G06F 3/0647 (20130101)
G06F 3/0673 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726961 Graham
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) BWXT mPower, Inc. (Charlotte, North Carolina)
ASSIGNEE(S) BWXT mPower, Inc. (Charlotte, North Carolina)
INVENTOR(S) Thomas G. Graham (Lynchburg, Virginia)
ABSTRACT In conjunction with a pressurized water reactor (PWR) and a pressurizer configured to control pressure in the reactor pressure vessel, a decay heat removal system comprises a pressurized passive condenser, a turbine-driven pump connected to suction water from at least one water source into the reactor pressure vessel; and steam piping configured to deliver steam from the pressurizer to the turbine to operate the pump and to discharge the delivered steam into the pressurized passive condenser. The pump and turbine may be mounted on a common shaft via which the turbine drives the pump. The at least one water source may include a refueling water storage tank (RWST) and/or the pressurized passive condenser. A pressurizer power operated relief valve may control discharge of a portion of the delivered steam bypassing the turbine into the pressurized passive condenser to control pressure in the pressurizer.
FILED Tuesday, August 29, 2017
APPL NO 15/689724
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 1/09 (20130101)
G21C 9/012 (20130101)
G21C 15/182 (20130101) Original (OR) Class
G21C 15/185 (20190101)

Nuclear Power Plant
G21D 1/00 (20130101)
G21D 3/06 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727428 Ramos Murillo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Universidad Autonoma de Ciudad Juarez (Ciudad Juarez, Mexico);  National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) NATIOINAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SA (Albuquerque, New Mexico);  UNIVERSIDAD AUTONOMA DE CIUDAD JUAREZ (Ciudad Juarez, Mexico)
INVENTOR(S) Manuel Antonio Ramos Murillo (Cd Juarez, Mexico);  John Joseph Nogan (NW Albuquerque, New Mexico);  Roberto Carlos Ambrosio Lazaro (San Pedro Cholula, Mexico);  Claudia Alejandra Rodriguez González (Cd Juarez, Mexico);  Manuela Ortiz Diaz (Cd Juarez, Mexico);  Jose Luis Enriquez-Carrejo (Cd Juarez, Mexico);  Jose Mireles Jr. Garcia (Cd. Juarez, Mexico)
ABSTRACT The embodiment of this invention lies on experimental evidence of photoconductivity activity of a hybrid solar cell, organic/chalcogenide. The device is made of thin layers of conductive indium-tin-oxide (ITO) on glass with a 100 nm layer of chalcogenide molybdenum di-sulfide (MoS2) and a thin layer of about ˜50 nm of complex organic compound assembled at room temperature. The device was tested to conventional electrical transport measurements in the regime of −1V to 1V under electromagnetic radiation simulator at 100 mW/cm2. Results indicate solar conversion efficiency of 2.48% and current density of 6.35 mA/cm2.
FILED Friday, February 01, 2019
APPL NO 16/265577
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02568 (20130101)
H01L 51/0045 (20130101)
H01L 51/442 (20130101)
H01L 51/4213 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/542 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727474 Allcorn et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Eric Allcorn (Albuquerque, New Mexico);  Ganesan Nagasubramanian (Albuquerque, New Mexico);  Christopher A. Apblett (Albuquerque, New Mexico)
ABSTRACT Cast components can improve the effectiveness of current state-of-the-art in thermal battery processing technology in terms of cost, labor, materials usage, and flexibility. Cast components can include cast cathodes, anodes, and separators.
FILED Wednesday, January 10, 2018
APPL NO 15/866935
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/145 (20130101)
H01M 4/08 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/0485 (20130101)
H01M 4/621 (20130101)
H01M 6/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727488 Helms et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California);  The Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) The Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Brett A. Helms (San Francisco, California);  Peter D. Frischmann (Berkeley, California);  Yet-Ming Chiang (Cambridge, Massachusetts);  Frank Y. Fan (Cambridge, Massachusetts);  Sean E. Doris (San Francisco, California);  Laura C. H. Gerber (Berkeley, California)
ABSTRACT Metal-sulfur energy storage devices also comprising new redox mediator compounds are described.
FILED Tuesday, August 11, 2015
APPL NO 15/502479
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 209/58 (20130101)
C07D 471/06 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/62 (20130101) Original (OR) Class
H01M 4/382 (20130101)
H01M 4/606 (20130101)
H01M 4/5815 (20130101)
H01M 8/188 (20130101)
H01M 10/052 (20130101)
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727518 Stahl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Shannon S. Stahl (Madison, Wisconsin);  James B. Gerken (Madison, Wisconsin);  Colin W. Anson (Madison, Wisconsin);  Thatcher W. Root (Madison, Wisconsin);  Yuliya Preger (Madison, Wisconsin)
ABSTRACT Anode half-cells for the electrocatalytic oxidation of a liquid or gaseous fuel or other reductant are disclosed, along with electrochemical cells that include such half-cells. The anode half-cells include redox mediator/heterogeneous redox catalyst pairs within an electrolyte solution that is also in contact with an electrode. The electrode is not in direct contact with the heterogeneous catalyst. The redox mediator must include at least one carbon atom and be capable of transferring or accepting electrons and protons while undergoing reduction or oxidation. In operation, the fuel or other reductant is oxidized and the redox mediator is reduced at the heterogeneous catalyst. The reduced form of the redox mediator can then migrate to the electrode, where it is converted back to its oxidized form, which can then migrate back to the heterogeneous catalyst, where the cycle is repeated. The disclosed anode half-cells can be used in electrochemical cells, such as in fuel cells that produce electricity, or in electrosynthetic cells that produce one or more desired chemical products.
FILED Tuesday, June 12, 2018
APPL NO 16/005783
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/60 (20130101)
H01M 4/368 (20130101)
H01M 4/5825 (20130101)
H01M 8/20 (20130101) Original (OR) Class
H01M 2008/1095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727539 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)
INVENTOR(S) Bin Li (Richland, Washington);  Huilin Pan (Richland, Washington);  Zimin Nie (Richland, Washington);  Jun Liu (Richland, Washington);  Vincent L. Sprenkle (Richland, Washington)
ABSTRACT Disclosed are cathodes having electron-conductive high-surface-area materials, aqueous non-halide-containing electrolytes, secondary zinc-iodine energy storage devices using the same, and methods for assembling the same. The disclosed high-surface-area materials and the aqueous non-halide-containing electrolyte solutions can contribute together to the confinement of the active iodine species in the cathode and to the minimization of shuttle effects and self-discharging. The non-halide-containing electrolyte salts can facilitate preferential adsorption of the iodine species to the cathode material rather than dissolution in the aqueous electrolyte solution, thereby contributing to the confinement of the active iodine species.
FILED Tuesday, October 03, 2017
APPL NO 15/724051
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/42 (20130101)
H01M 4/388 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 4/668 (20130101)
H01M 4/5815 (20130101)
H01M 10/04 (20130101)
H01M 10/38 (20130101)
H01M 10/365 (20130101) Original (OR) Class
H01M 2004/027 (20130101)
H01M 2300/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727762 Aeloiza et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) ABB Inc. (Raleigh, North Carolina)
ASSIGNEE(S) ABB Schweiz AG (Baden, Switzerland)
INVENTOR(S) Eddy Aeloiza (Apex, North Carolina);  Rolando Burgos (Blacksburg, Virginia);  Yu Du (Raleigh, North Carolina)
ABSTRACT A multi-phase power converter includes two or more multi-phase, bi-directional, multi-level, switching power converter subcircuits, connected in parallel at respective AC and DC sides, so as to provide a multi-channel, bi-directional, multi-level configuration. The AC sides of the switching converter subcircuits are directly coupled to one another and to a multi-phase AC input via series interface reactors, and the DC sides of the switching converter subcircuits are directly connected to one another and to a common split-capacitor bank at each level of the multi-level outputs of the switching converter subcircuits. A control circuit is configured to selectively control one or more switching semiconductor devices in each of the switching converter subcircuits. In some embodiments, the control circuit includes a closed-loop zero-sequence controller and a zero-sequence generator configured to eliminate circulating current among the switching converter subcircuits and to balance voltages across levels of the common split-capacitor bank.
FILED Friday, July 15, 2016
APPL NO 15/211844
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/08 (20130101)
H02M 1/12 (20130101)
H02M 1/14 (20130101)
H02M 1/42 (20130101)
H02M 7/68 (20130101) Original (OR) Class
H02M 7/81 (20130101)
H02M 7/487 (20130101)
H02M 7/493 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727763 Post et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Richard F. Post (Walnut Creek, California);  Lisle B. Hagler (Livermore, California)
ABSTRACT Electrostatic generator electrodes mounted on the outer surface of a fiber-composite rotor. The conducting strips are mounted with a slight tilt in angle such that the electrodes will experience no tension or compression effects as the rotor spins up or slows down. The compression would come about from effects associated with the Poisson Ratio. This change can eliminate any metal fatigue or loss of bonding that might have arisen if the electrodes were to be aligned with the axis.
FILED Friday, May 24, 2019
APPL NO 16/421559
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electric Machines Not Otherwise Provided for
H02N 1/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728270 Neil
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Joshua Charles Neil (Jemez Springs, New Mexico)
ABSTRACT Creation of new edges in a network may be used as an indication of a potential attack on the network. Historical data of a frequency with which nodes in a network create and receive new edges may be analyzed. Baseline models of behavior among the edges in the network may be established based on the analysis of the historical data. A new edge that deviates from a respective baseline model by more than a predetermined threshold during a time window may be detected. The new edge may be flagged as potentially anomalous when the deviation from the respective baseline model is detected. Probabilities for both new and existing edges may be obtained for all edges in a path or other subgraph. The probabilities may then be combined to obtain a score for the path or other subgraph. A threshold may be obtained by calculating an empirical distribution of the scores under historical conditions.
FILED Thursday, June 07, 2018
APPL NO 16/002870
ART UNIT 2498 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/577 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/02 (20130101)
G06N 5/022 (20130101)
G06N 5/045 (20130101)
G06N 7/005 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/002 (20130101)
H04L 63/1408 (20130101)
H04L 63/1416 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
H04L 63/1433 (20130101)
H04L 2463/144 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728282 Mestha et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Lalit Keshav Mestha (North Colonie, New York);  Olugbenga Anubi (Niskayuna, New York);  Hema Achanta (Niskayuna, New York)
ABSTRACT Input signals may be received from monitoring nodes of the industrial asset, each input signal comprising time series data representing current operation. A neutralization engine may transform the input signals into feature vectors in feature space, each feature vector being associated with one of a plurality of overlapping batches of received input signals. A dynamic decision boundary may be generated based on the set of feature vectors, and an abnormal state of the asset may be detected based on the set of feature vectors and a predetermined static decision boundary. An estimated neutralized value for each abnormal feature value may be calculated based on the dynamic decision boundary and the static decision boundary such that a future set of feature vectors will be moved with respect to the static decision boundary. An inverse transform of each estimated neutralized value may be performed to generate neutralized signals comprising time series data that are output.
FILED Wednesday, May 23, 2018
APPL NO 15/986996
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/0297 (20130101)

Electric Digital Data Processing
G06F 21/50 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/14 (20130101)
H04L 63/1416 (20130101)
H04L 63/1466 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10722148 Zhang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Zhenghao Zhang (Tallahassee, Florida);  Avishek Mukherjee (Tallahassee, Florida);  Subhankar Banerjee (Tallahassee, Florida)
ABSTRACT Provided herein are systems and devices capable of detecting an event, such as the fall of a human. The devices may include a motion sensor, a heat sensor, and a vibration sensor. The devices and systems also may include an alarm and/or communication device configured to function when the event occurs.
FILED Wednesday, October 24, 2018
APPL NO 16/169028
ART UNIT 2631 — Digital Communications
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/015 (20130101)
A61B 5/0022 (20130101)
A61B 5/0077 (20130101)
A61B 5/747 (20130101)
A61B 5/1116 (20130101)
A61B 5/1117 (20130101) Original (OR) Class
A61B 5/1118 (20130101)
A61B 5/1495 (20130101)
A61B 5/6889 (20130101)
A61B 5/7264 (20130101)
A61B 2560/0252 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 13/00 (20130101)
G01P 15/00 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 13/19 (20130101)
G08B 21/043 (20130101)
G08B 21/0446 (20130101)
G08B 21/0461 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722719 Kim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey);  PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Younghyun Kim (West Lafayette, Indiana);  Woo Suk Lee (Brownsburg, Indiana);  Vijay Raghunathan (West Lafayette, Indiana);  Niraj K. Jha (Princeton, New Jersey);  Anand Raghunathan (West Lafayette, Indiana)
ABSTRACT According to some embodiments, a system for securing communications between an implantable wearable medical device (IWMD) and an external device (ED) is disclosed. The system includes a wireless radio frequency (RF) channel configured for communication between the IWMD and the ED. The system further includes a vibration-based side channel configured for verifying communication between the IWMD and the ED such that the RF channel is activated only when the IWMD detects a vibration signal generated by an ED.
FILED Friday, February 12, 2016
APPL NO 15/552180
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/0028 (20130101)
A61B 5/0031 (20130101)
A61B 5/686 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/37217 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/18 (20130101)

Wireless Communication Networks
H04W 12/02 (20130101)
H04W 12/04 (20130101)
H04W 12/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10722889 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Bahige G. Abdallah (Casa Grande, Arizona)
ABSTRACT A microfluidic apparatus, systems and methods for microfluidic crystallization based on gradient mixing. In one embodiment, the apparatus includes (a) a first layer, (b) a plurality of first channels and a plurality of vacuum chambers both arranged in the first layer, where the plurality of vacuum chambers are each coupled to at least one of the first channels, (c) a membrane having first and second surfaces, where the first surface of the membrane is coupled to the first layer, (d) a second layer coupled to the second surface of the membrane, (e) a plurality of wells and a plurality of second channels both arranged in the second layer, where the wells are each coupled to at least one of the plurality of second channels and (f) a plurality of barrier walls each disposed in the plurality of second channels and arranged opposite to one of the plurality of vacuum chambers.
FILED Monday, December 31, 2018
APPL NO 16/237158
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0652 (20130101)
B01L 2300/16 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0848 (20130101)
B01L 2300/0861 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0887 (20130101)
B01L 2300/0896 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0424 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723921 Loy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Douglas A. Loy (Tucson, Arizona);  Pamela B. Vandiver (Tucson, Arizona);  Nancy N. Odegaard (Tucson, Arizona);  Kevin M. Frederick (Tucson, Arizona);  Peter McFadden (Tucson, Arizona)
ABSTRACT Coumarin modification of epoxies provide for epoxy adhesives that fluoresce under short wave ultraviolet irradiation while remaining invisible under normal light. Furthermore, these modified epoxy adhesives can have increased adhesive bond strengths. In addition, photochemical curing of an epoxy modified coumarin and a hardening agent with UV irradiation at certain wavelengths affords an epoxy adhesive composition. Further UV irradiation of the composition at certain wavelengths causes photoscission, which breaks the crosslinks that make the cured epoxy adhesive insoluble and intractable.
FILED Friday, January 27, 2017
APPL NO 16/074007
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/1545 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 57/02 (20130101)
C09B 69/109 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 11/06 (20130101) Original (OR) Class
C09J 163/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724049 Jin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hailing Jin (Riverside, California)
ABSTRACT The present invention relates to pathogen-resistant plants. In one aspect, plants comprising a heterologous expression cassette are provided, wherein the expression cassette comprises a polynucleotide that inhibits expression of a fungal pathogen dicer-like (DCL) gene and wherein the plant has increased resistance to a fungal pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
FILED Friday, July 24, 2015
APPL NO 14/809063
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/8218 (20130101)
C12N 15/8282 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724060 Schall et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Constance A. Schall (Sylvania, Ohio);  Samira Vasheghani Farahani (Toledo, Ohio)
ABSTRACT A method for pretreating lignocellulosic biomass having a lignin component, a hemicellulose component, and a cellulose component, for conversion to sugar is disclosed. Also disclosed is the pretreated lignocellulosic biomass resulting from the method.
FILED Monday, February 16, 2015
APPL NO 15/119487
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Polysaccharides; Derivatives Thereof
C08B 37/0057 (20130101)

Derivatives of Natural Macromolecular Compounds
C08H 6/00 (20130101)
C08H 8/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101) Original (OR) Class
C12P 19/14 (20130101)
C12P 2201/00 (20130101)

Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101)
C13K 13/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724089 Bashir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Rashid Bashir (Champaign, Illinois);  Anurup Ganguli (Champaign, Illinois);  Farhad Kosari (Rochester, Minnesota)
ABSTRACT Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique.
FILED Friday, October 06, 2017
APPL NO 15/727026
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/5085 (20130101)
B01L 3/50851 (20130101)
B01L 2200/0642 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0858 (20130101)
B01L 2300/0893 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101)
C12N 15/1003 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2521/107 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101)
G01N 2001/282 (20130101)
G01N 2001/2873 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
G16B 30/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724097 Patel
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
Office of The Director (OD)
Office of General Counsel(OGC)
APPLICANT(S) University of South Florida (Tampa, Florida);  THE U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF GENERAL COUNSEL (Washington, District of Columbia)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  The United States Government as Represented by the Department of Veterans Affairs Office of General Counsel (Washington, District of Columbia)
INVENTOR(S) Niketa A. Patel (Land O'Lakes, Florida)
ABSTRACT Described herein are assays, methods, and devices for diagnosing/prognosing diabetes, metabolic syndrome, pre-diabetic state and/or the early-onset of diabetes in a subject. The assays, methods, and devices described herein can be configured to detect one or more long-coding RNAs in a sample from a subject.
FILED Monday, November 30, 2015
APPL NO 15/528894
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724153 Cola et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Baratunde Cola (Atlanta, Georgia);  Thomas L. Bougher (Atlanta, Georgia);  Kyriaki Kalaitzidou (Atlanta, Georgia);  Virendra Singh (Decatur, Georgia);  Matthew Smith (Atlanta, Georgia)
ABSTRACT Nano structured surfaces and bulk composite materials which exhibit tunable surface morphology, wettability, thermal conductivity, and total thermal resistance properties, and methods of fabrication and uses thereof are described herein. Arrays of vertically-aligned nanostructures produced via a template assisted fabrication approach using nanoporous templates, or alternatively, via an electropolymerization process are described. As a result, control over the surface morphology and wettability can be achieved using the selective template etching process. The composite materials also demonstrate tunable thermal and electrical properties based on the methods of their fabrication. The arrays of polymeric nanostructures are chemically, mechanically, and thermally robust and can serve as soft substrates with heat dissipation capability for use in the fabrication of thermal management materials, tunable wetting for microfluidic applications, and for use in heterojunction organic photovoltaic cells.
FILED Thursday, June 11, 2015
APPL NO 15/317269
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 9/06 (20130101)
C25B 11/02 (20130101)
C25B 11/04 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/38 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 6/74 (20130101) Original (OR) Class

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2401/021 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/42 (20130101)
H01L 23/373 (20130101)
H01L 23/3737 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724198 Kavazanjian et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
U.S. State Government
State of Arizona
APPLICANT(S) Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Edward Kavazanjian (Tempe, Arizona);  Nasser Hamdan (Scottsdale, Arizona)
ABSTRACT The present invention provides methods for mineral precipitation of porous particulate starting materials using isolated urease.
FILED Tuesday, October 28, 2014
APPL NO 15/029866
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/002 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 11/18 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/42 (20130101)
C02F 1/286 (20130101)
C02F 1/5236 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 41/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/78 (20130101)
C12N 9/80 (20130101)

Enzymes
C12Y 305/01005 (20130101)

Foundations; Excavations; Embankments; Underground or Underwater Structures
E02D 3/12 (20130101) Original (OR) Class
E02D 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724897 Xu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Wayne State University (Detroit, Michigan)
ASSIGNEE(S) National Science Foundation (Alexandria, Virginia)
INVENTOR(S) Yong Xu (Troy, Michigan);  Yating Hu (Detroit, Michigan);  Hongen Tu (Detroit, Michigan)
ABSTRACT This disclosure describes a sensor for detecting vibrations, particularly low-frequency vibrations. The sensor is of a cascaded gapped cantilever construction and may include a single sensing beam extending from a base to a proof mass across the plurality of gaps, a mechanical beam opposite the piezoelectric beam. The sensor may be included in a system including a housing, a support, and electronic components for converting and measuring signal. The sensor may be mounted to an item of furniture, such as a bed or a sofa, and measure physiological data including ballistocardiogram and respiratory data of a subject positioned on the furniture.
FILED Thursday, June 16, 2016
APPL NO 15/736046
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1102 (20130101)
A61B 5/4809 (20130101)
A61B 5/6892 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 11/08 (20130101) Original (OR) Class

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/09 (20130101)
G01P 15/0922 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724974 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Yihua Bruce Yu (Ellicott City, Maryland);  Marc Taraban (Gaithersburg, Maryland);  Yue Feng (Niantic, Connecticut)
ABSTRACT The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation.
FILED Wednesday, November 13, 2019
APPL NO 16/682157
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101) Original (OR) Class
G01N 33/15 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/448 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725036 Cornish et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Virginia Wood Cornish (New York, New York);  Nili Ostrov (Boston, Massachusetts);  Miguel Jimenez (New York, New York);  Sonja Billerbeck (New York, New York)
ABSTRACT The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample.
FILED Tuesday, May 16, 2017
APPL NO 15/596837
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)
C12Q 1/005 (20130101)
C12Q 1/06 (20130101)
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/566 (20130101) Original (OR) Class
G01N 33/569 (20130101)
G01N 33/5023 (20130101)
G01N 33/5038 (20130101)
G01N 33/5695 (20130101)
G01N 33/56911 (20130101)
G01N 33/56916 (20130101)
G01N 33/56961 (20130101)
G01N 2333/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725135 Meriles et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) Carlos A. Meriles (Fort Lee, New Jersey);  Daniela Pagliero (Fort Lee, New Jersey);  Abdelghani Laraoui (Bronx, New York)
ABSTRACT A method of inducing spin polarization in an analyte is provided. The method exposes 14N spin defect centers embedded within 25 nm of a diamond surface to a magnetic field while an analyte is near the surface. The 14N spin defect centers are polarized by treatment with an electromagnetic wave protocol having a visible light pulse (p0); a microwave pulse (mw1), a radio frequency pulse (rf1), a microwave pulse (mw2) and a radio frequency pulse (rf2) resulting in polarization of the nuclear spins of the 14N spin defect centers. Polarized spins in the 14N spin defect centers induce spin polarization in the analyte.
FILED Friday, January 04, 2019
APPL NO 16/240119
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/282 (20130101)
G01R 33/5605 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725209 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Baomin Wang (State College, Pennsylvania);  Noel C. Giebink (State College, Pennsylvania)
ABSTRACT A method for generating antireflective coatings for polymeric substrates using a deposition process and/or a dissolving process can provide a coating onto the outer surface of the substrate. Some embodiments can include a GLAD generated fluoropolymer coating or a co-evaporated fluoropolymer coating on a substrate that may achieve ultralow refractive index as well as improved adhesion and durability properties on polymeric substrates. In some embodiments, the deposition process is performed such that a fluoropolymer can be evaporated to form chain fragments of the fluoropolymer. The chain fragments diffused into the substrate can subsequently re-polymerize, interlocking with the polymer chains of the substrate. In some embodiments, the co-evaporation process can form a nanoporous polymer chain scaffold of the fluoropolymer, from which a sacrificial material can be dissolved out. The formed coating can be a multilayer or continuously-graded antireflective coating that has strong adhesion with the substrate.
FILED Tuesday, January 09, 2018
APPL NO 16/465641
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 127/12 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/12 (20130101)
G02B 1/111 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10725373 Kumar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Ratnesh Kumar (Ames, Iowa);  Shawana Tabassum (Ames, Iowa);  Liang Dong (Ames, Iowa)
ABSTRACT A technique, and its applications, for high resolution, rapid, and simple nanopatterning. The general method has been demonstrated in several forms and applications. One is patterning nanophotonic structures at an optical fiber tip for refractive index sensing. Another is patterning nanoresonator structures on a sensor substrate for plasmonic effect related detection of VOCs. In the latter example, a graphene oxide coated plasmonic crystal as a gas sensor capable of identifying different gas species using an array of such structures. By coating the surface of multiple identical plasmonic crystals with different thicknesses of Graphene-Oxide (GO) layer, the effective refractive index of the GO layer on each plasmonic crystal is differently modulated when exposed to a specific gas. Identification of various gas species is accomplished using pattern recognition algorithm.
FILED Monday, October 23, 2017
APPL NO 15/791174
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 41/42 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/02 (20130101)
G02B 1/045 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101) Original (OR) Class
G03F 7/2012 (20130101)
G03F 7/2014 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726330 Ferdman et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Michael Ferdman (Stony Brook, New York);  Peter Milder (Sound Beach, New York);  Manoj Alwani (Jersey City, New Jersey)
ABSTRACT System, method, and accelerator to process a convolutional neural network. In accordance therewith, a tile structure having input data values is loaded for a convolution layer. Each tile of the tile structure corresponds to a respective feature map in a set of input feature maps. The tile structure of each iteration represents a different subset of data values in the input feature maps. Intermediate data values associated with a subset of the data values of the input feature maps in the current intermediate tile structure are reused, when the intermediate data values of a previous tile structure overlap values to be computed in the current tile structure. Intermediate non-overlapping data values that are associated with the subset of the data values in the current tile structure are computed using associated filters having weight data values. Available reused intermediate data values and computed intermediate data values are buffered as intermediate data.
FILED Wednesday, October 11, 2017
APPL NO 16/335801
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/15 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/063 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726351 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Kangbo Li (Madison, Wisconsin);  Robert Francis McDermott, III (Madison, Wisconsin);  Maxim George Vavilov (Middleton, Wisconsin)
ABSTRACT A system and method for controlling superconducting qubits is provided. In some aspects the method includes assembling, using a controller of a quantum computing system, a pulse subsequence that comprises pairs of voltage pulses timed symmetrically with respect to a period corresponding to a qubit frequency of a superconducting qubit in the quantum computing system. The method also includes generating, using the controller, a pulse sequence using a repetition of a pulse subsequence. The method further includes controlling the superconducting qubit by applying the pulse sequence to the superconducting qubit using a single flux quantum (“SFQ”) driver coupled thereto.
FILED Friday, February 01, 2019
APPL NO 16/265867
ART UNIT 2637 — Optical Communications
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Pulse Technique
H03K 19/1958 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727187 Tan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Aik Jun Tan (Cambridge, Massachusetts);  Geoffrey S. D. Beach (Winchester, Massachusetts)
ABSTRACT A solid oxide battery includes a solid electrolyte disposed between a first electrode and a second electrode. The first electrode and the second electrode are coupled to an external source or load to charge or discharge the solid oxide battery. The solid electrolyte is formed from a proton conducting material to transport and store hydrogen, which is the source of chemical energy. The second electrode is formed from a noble metal configured to induce formation of oxygen vacancies at the interface between the second electrode and the solid electrolyte. The oxygen vacancies are used to split water molecules during charging of the solid oxide battery, which results in the generation of hydrogen. Under bias, the hydrogen ions are transported into the solid electrolyte and stored. During discharge, a reverse process occurs where hydrogen is used to generate water and electricity.
FILED Tuesday, June 19, 2018
APPL NO 16/012155
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/10 (20130101)
C25B 9/10 (20130101)
C25B 13/04 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/58 (20130101) Original (OR) Class
H01L 23/5387 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/184 (20130101)
H01M 8/1246 (20130101)
H01M 8/1286 (20130101)
H01M 2008/1293 (20130101)
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10723489 Conversano et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Ryan W Conversano (Pasadena, California);  Dan M Goebel (Pasadena, California);  Ira Katz (Pasadena, California);  Richard R Hofer (Pasadena, California)
ABSTRACT A low-power Hall thruster gains significantly improved efficiency by a combination of features, including a single piece, h-shaped magnetic screen which enables a more efficient internal volume utilization as well as optimal magnetic shielding; an internally mounted cathode with varying diameter further decreases the footprint of the thruster; an anode with multiple baffles connected by axially oriented holes generates a highly azimuthally uniform propellant flow.
FILED Thursday, November 29, 2018
APPL NO 16/205048
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/405 (20130101) Original (OR) Class

Producing a Reactive Propulsive Thrust, Not Otherwise Provided for
F03H 1/0012 (20130101)
F03H 1/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723857 Viggiano et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U. S. A., as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Rocco P. Viggiano (Elyria, Ohio);  Mary Ann B. Meador (Strongsville, Ohio)
ABSTRACT A polyimide aerogel and method of making the aerogel is disclosed. The polymer backbone of the aerogel includes a cardo-diamine. The disclosed polyimide aerogel is less susceptible to temperature induced shrinkage than a polyimide aerogel that does not include a cardo-diamine.
FILED Thursday, April 13, 2017
APPL NO 15/486732
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 73/1067 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/28 (20130101) Original (OR) Class
C08J 2201/026 (20130101)
C08J 2201/0502 (20130101)
C08J 2205/026 (20130101)
C08J 2379/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723912 Doss et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Jereme R. Doss (Hampton, Virginia);  John W. Connell (Yorktown, Virginia);  Christopher J. Wohl, Jr. (Portsmouth, Virginia)
ABSTRACT Various embodiments provide epoxy modified fluorinated urethane compositions that may provide desirable bulk mechanical properties of conventional coatings, adhesives, or structural matrix resins, while simultaneously exhibiting surface properties that may reduce surface contamination. Various embodiments provide formulations comprising epoxy modified fluorinated alkyl ether including urethane oligomer or polymer resins that may possess the requisite thermal, mechanical, chemical, and optical properties while achieving a low surface energy. In various embodiments, such resins may be prepared from random urethane oligomer compositions including fluorinated alkyl ether segments, in which the oligomers may be terminated with amino groups and subsequently reacted with epoxy including monomers or oligomers.
FILED Friday, December 02, 2016
APPL NO 15/367943
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/02 (20130101)
B05D 3/002 (20130101)
B05D 3/108 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/10 (20130101)
C08G 18/58 (20130101)
C08G 18/73 (20130101)
C08G 18/246 (20130101)
C08G 18/755 (20130101)
C08G 18/3206 (20130101)
C08G 18/3812 (20130101)
C08G 18/4825 (20130101)
C08G 18/4833 (20130101)
C08G 18/5015 (20130101)
C08G 18/6674 (20130101)
C08G 18/6674 (20130101)
C08G 18/7621 (20130101)
C08G 59/50 (20130101)
C08G 65/007 (20130101)
C08G 65/33348 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 3/30 (20130101)
C08K 3/30 (20130101)
C08K 3/36 (20130101)
C08K 3/36 (20130101)
C08K 2003/2265 (20130101)
C08K 2003/3009 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 163/00 (20130101)
C09D 175/04 (20130101)
C09D 175/04 (20130101)
C09D 175/04 (20130101)
C09D 175/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724030 Goodwin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Thomas J. Goodwin (Kemah, Texas);  Linda C. Shackelford (Webster, Texas)
ABSTRACT The present invention provides a system for delivering a time-varying stimulation field to a subject. In the system, a power source, a control component and a transmission component operate as a stimulation field generator to provide a predetermined time-varying stimulation field to up-regulate or down-regulate an expression level of human genes. The present invention also provides a wearable apparatus for delivering the time-varying magnetic field to mammalian cells associated with bone formation in a subject. The wearable apparatus contains the stimulation field generator in a housing. The resulted modification on gene regulation of these genes and mammalian cells promotes the retention, repair of and reduction of compromised mammalian cartilage, bone, and associated tissue.
FILED Monday, February 19, 2018
APPL NO 15/899069
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724478 Morgan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota)
ASSIGNEE(S) Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota)
INVENTOR(S) Richard E. Morgan (Huntsville, Alabama);  Craig L. Meeks (Meridianville, Alabama)
ABSTRACT Insulation materials have a coating of a partially cured polymer on a plurality of fibers, and the plurality of coated fibers in a cross-linked polymeric matrix. Insulation may be formed by applying a preceramic polymer to a plurality of fibers, heating the preceramic polymer to form a partially cured polymer over at least portions of the plurality of fibers, disposing the plurality of fibers in a polymeric material, and curing the polymeric material. A rocket motor may be formed by disposing a plurality of coated fibers in an insulation precursor, curing the insulation precursor to form an insulation material without sintering the partially cured polymer, and providing an energetic material over the polymeric material. An article includes an insulation material over at least one surface.
FILED Thursday, December 01, 2016
APPL NO 15/366518
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/00 (20130101)
C04B 35/83 (20130101)
C04B 35/6269 (20130101)
C04B 35/62863 (20130101)
C04B 35/62871 (20130101)
C04B 2235/483 (20130101)
C04B 2235/5212 (20130101)
C04B 2235/5248 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/36 (20130101)

Jet-propulsion Plants
F02K 1/822 (20130101) Original (OR) Class
F02K 9/00 (20130101)
F02K 9/32 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2300/6033 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/308 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/1362 (20150115)
Y10T 428/249921 (20150401)
Y10T 442/2631 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724480 Woodruff et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) CU Aerospace, LLC (Champaign, Illinois)
ASSIGNEE(S) CU Aerospace, LLC (Champaign, Illinois)
INVENTOR(S) Curtis Woodruff (Savoy, Illinois);  Darren King (Champaign, Illinois);  Rodney Burton (Champaign, Illinois);  David L. Carroll (Champaign, Illinois);  Neil John Nejmanowski (Urbana, Illinois)
ABSTRACT The monofilament vaporization propulsion system in accordance with an embodiment of the invention includes a mechanical feed, an elongated barrel, a heater block, a tube, and a nozzle. A monofilament solid propellant is wound around a spool and fed into the mechanical feed. The elongated barrel is configured to receive the solid propellant towards a second end. The heater block is positioned near the second end of the barrel and configured to heat the propellant into a liquid propellant as the solid propellant moves towards the second end. The tube receives the liquid propellant and is configured to evaporate the liquid propellant into a gaseous propellant. The gaseous propellant enters a nozzle in communication with the tube. The gaseous propellant being fed into the nozzle entrance expands there-through to create propulsion out an nozzle exit.
FILED Friday, March 16, 2018
APPL NO 15/922966
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 9/10 (20130101)
F02K 9/24 (20130101) Original (OR) Class
F02K 9/97 (20130101)
F02K 9/346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727325 Han et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Jin-Woo Han (San Jose, California);  Meyya Meyyappan (San Jose, California)
ABSTRACT A horizontal vacuum channel transistor is provided. The horizontal transistor includes a substrate, horizontal emitter and collector electrodes formed in a layer of semiconductor material of the substrate, and a horizontal insulated gate located between the emitter and collector electrodes. The emitter electrode includes multiple horizontally-aligned emitter tips connected to a planar common portion, and the collector electrode includes a planar portion. The gate includes multiple horizontally-aligned gate apertures passing through the gate that each correspond to one of the emitter tips of the emitter electrode. The minimum distance between the emitter and collector electrodes is less than about 180 nm. Also provided are a vertical vacuum channel transistor having vertically-stacked emitter and collector electrodes, and methods for fabricating vacuum channel transistors.
FILED Thursday, March 22, 2018
APPL NO 15/933240
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/0665 (20130101)
H01L 29/1033 (20130101)
H01L 29/7394 (20130101) Original (OR) Class
H01L 29/41708 (20130101)
H01L 29/66325 (20130101)
H01L 29/66439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728426 Koshti
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ajay M. Koshti (League City, Texas)
ABSTRACT Methods and systems for analyzing and processing digital data comprising a plurality of infra-red (IR) video images acquired by a pulse thermography system are used to compute video data from the raw and smoothed video data acquired for the performance of non-destructive evaluation. New video data types computed may include but are not limited to contrast evolution data such as normalized contrast, converted contrast and normalized temperature contrast. Additionally, video data types computed comprise surface temperature, surface temperature rise and temperature simple contrast.
FILED Wednesday, August 16, 2017
APPL NO 15/678988
ART UNIT 2481 — Recording and Compression
CURRENT CPC
Printing, Duplicating, Marking, or Copying Processes; Colour Printing,
B41M 5/26 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/72 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00134 (20130101)
G06K 9/3233 (20130101)

Image Data Processing or Generation, in General
G06T 7/62 (20170101)

Pictorial Communication, e.g Television
H04N 3/09 (20130101) Original (OR) Class
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10723726 Barbosa
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GB006, INC. (San Diego, California)
ASSIGNEE(S) GB006, INC. (San Diego, California)
INVENTOR(S) Antonio J. Barbosa (Ave Maria, Florida)
ABSTRACT The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating 2 integrin-mediated diseases and conditions using the salts and crystalline forms.
FILED Friday, June 10, 2016
APPL NO 15/735560
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Acyclic or Carbocyclic Compounds
C07C 215/08 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724079 Mitra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Lucira Health, Inc. (Emeryville, California)
ASSIGNEE(S) Lucira Health, Inc. (Emeryville, California)
INVENTOR(S) Debkishore Mitra (Berkeley, California);  Ivan Krastev Dimov (Union City, California);  John Robert Waldeisen (Berkley, California)
ABSTRACT Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED Wednesday, March 20, 2019
APPL NO 16/359913
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2527/119 (20130101)
C12Q 2527/125 (20130101)
C12Q 2563/173 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727947 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT The present invention reduces the level of optical reflections created in a photonic integrated circuit (PIC) going back into an integrated laser through Reflection Engineering; optimizing the phase/timing and position of optical reflections inherent to a PIC design while adding engineered reflections to the PIC to allow inherent reflections to be reduced or eliminated. The Wavelength Division Multiplexed (WDM) geometric optical isolator of the present invention combines an array of closely spaced WDM lasers with an array of modulators in a novel geometry in order to provide effective optical isolation of the lasers.
FILED Wednesday, April 24, 2019
APPL NO 16/393842
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101)
H04B 10/50 (20130101)
H04B 10/516 (20130101)
H04B 10/25759 (20130101) Original (OR) Class
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10728149 Ramanujan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Architecture Technology Corporation (Eden Prairie, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Ranga S. Ramanujan (Medina, Minnesota);  Benjamin L. Burnett (Prior Lake, Minnesota);  Barry A. Trent (Chanhassen, Minnesota);  Jafar Al-Gharaibeh (Bloomington, Minnesota)
ABSTRACT A method of routing a packet from a routing device includes receiving a first packet having a first header and a first data field. The first header has a final destination corresponding to a destination device communicatively coupled to the routing device via at least two parallel network links. A second packet having a second header and a second data field is sent over the first network link. The second data field is identical to the first data field. A destination address in the second header corresponds to a device on a first of the parallel network links. A third packet having a third header and a third data field is sent over the second network link. The third data field is identical to the first data field. a destination address in the third header corresponds to a device on a second of the parallel network links.
FILED Friday, May 12, 2017
APPL NO 15/593883
ART UNIT 2466 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/24 (20130101)
H04L 45/56 (20130101)
H04L 45/745 (20130101) Original (OR) Class
H04L 49/109 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10722561 Scoles et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia);  Washington State University (Pullman, Washington)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Glen A. Scoles (Moscow, Idaho);  Felicito Guerrero (Boerne, Texas);  Reginaldo Bastos (Pullman, Washington)
ABSTRACT A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus.
FILED Thursday, July 12, 2018
APPL NO 16/034042
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0003 (20130101) Original (OR) Class
A61K 2039/552 (20130101)
A61K 2039/55566 (20130101)

Peptides
C07K 14/43527 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723663 Vanotti et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Matias B. Vanotti (Florence, South Carolina);  Ariel A. Szogi (Florence, South Carolina)
ABSTRACT A system and method for separating nutrients, such as phosphorus and protein, from biological materials may be disclosed. Biological material, for example in the form of wet solids from raw manure, may first be separated out by a solid-liquid separator. The wet solids may then be dissolved in an acidic solution. The resulting supernatant from the acidic treatment may then be separated and phosphorus reclaimed therefrom. The resulting precipitate from the acidic treatment may be separated from the supernatant and treated with a basic solution. The resulting supernatant following the basic treatment may then be separated and protein reclaimed therefrom. In some embodiments, the supernatant resulting from the acidic treatment may itself be alkalinized, creating a precipitate which contains phosphorus solids and a supernatant which can be separated from the phosphorus solids and used as the basic solution with which to treat the precipitate resulting from the acidic treatment. Further, the system may be used to extract phosphorus and proteins from other biological materials, such as algae or crops.
FILED Monday, November 05, 2018
APPL NO 16/180287
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 25/04 (20130101)

Phosphatic Fertilisers
C05B 17/00 (20130101) Original (OR) Class

Peptides
C07K 1/145 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724089 Bashir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Rashid Bashir (Champaign, Illinois);  Anurup Ganguli (Champaign, Illinois);  Farhad Kosari (Rochester, Minnesota)
ABSTRACT Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique.
FILED Friday, October 06, 2017
APPL NO 15/727026
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/5085 (20130101)
B01L 3/50851 (20130101)
B01L 2200/0642 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0858 (20130101)
B01L 2300/0893 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101)
C12N 15/1003 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2521/107 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101)
G01N 2001/282 (20130101)
G01N 2001/2873 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
G16B 30/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10724181 Fanucci et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S) ZKxKZ, LLC (Lexington, Massachusetts)
ASSIGNEE(S) ZKxKZ, LLC (Lexington, Massachusetts)
INVENTOR(S) Jerome P. Fanucci (Lexington, Massachusetts);  Aram Stepanian (Seattle, Washington);  Adam Lanik (San Diego, California)
ABSTRACT A roundabout for vehicular traffic is provided from a plurality of modular blocks arranged in a generally circular roundabout pattern and affixed to a roadway or ground surface at an intersection of vehicle roadways. Roundabouts can be formed in any desired diameter. In some embodiments, the modular blocks can have a trapezoidal plan shape laid out in concentric rings. The trapezoidal shaped blocks can be cut from a length of board having a constant width and thickness. The modular blocks can be provided as a kit of parts delivered to worksite at an intersection of vehicle roadways where a roundabout is desired. Splitter islands, sidewalks, and curbing of blocks having appropriate shapes can also be provided.
FILED Friday, September 09, 2016
APPL NO 15/758947
ART UNIT 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair
E01C 1/02 (20130101) Original (OR) Class
E01C 5/00 (20130101)
E01C 5/20 (20130101)
E01C 5/22 (20130101)
E01C 11/00 (20130101)
E01C 11/221 (20130101)
E01C 19/52 (20130101)
E01C 2201/12 (20130101)
E01C 2201/20 (20130101)

Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like
E01F 1/00 (20130101)
E01F 9/50 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726717 Puckett et al.
FUNDED BY
Department of Transportation (USDOT)
University Transportation Centers (UTCs)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Darryl D. Puckett (Houston, Texas);  Michael J. Vickich (Houston, Texas)
ABSTRACT Methods and systems include determining travel information from vehicles. In one embodiment, a system monitors traffic on a roadway in real-time. The system includes a plurality of reader devices. The reader devices are capable of asynchronously capturing a unique network identifier of a device in a vehicle when the device is disposed in reader range of the reader devices. The reader device time stamps each captured unique network identifier. The time stamped unique network identifier is forwarded to a host module. The host module receives the time stamped unique network identifier. In addition, the host module determines travel information from the time stamped unique network identifier by comparing the time stamped unique network identifier for a particular vehicle to other time stamped unique network identifiers captured for the particular vehicle.
FILED Tuesday, January 09, 2018
APPL NO 15/866178
ART UNIT 2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Traffic Control Systems
G08G 1/0104 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10722644 Green et al.
FUNDED BY
Non-Profit Organization (NPO)
California Institute for Regenerative Medicine (CIRM)
U.S. State Government
State of California
APPLICANT(S) ViaCyte, Inc. (San Diego, California)
ASSIGNEE(S) Viacyte, Inc. (San Diego, California)
INVENTOR(S) Chad Green (San Diego, California);  Laura Martinson (San Diego, California);  Erik Olson (San Diego, California);  Val Anthony Bellora (San Diego, California);  Leah Elliott (San Diego, California);  Richard Alexander Grant (San Diego, California);  Donald Koenig (San Diego, California);  Giacomo Strollo (San Diego, California)
ABSTRACT Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.
FILED Thursday, November 20, 2014
APPL NO 15/528731
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/022 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/142 (20130101)
A61M 5/14276 (20130101) Original (OR) Class
A61M 37/0069 (20130101)
A61M 2209/045 (20130101)

Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking
B65B 3/003 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724198 Kavazanjian et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
U.S. State Government
State of Arizona
APPLICANT(S) Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Edward Kavazanjian (Tempe, Arizona);  Nasser Hamdan (Scottsdale, Arizona)
ABSTRACT The present invention provides methods for mineral precipitation of porous particulate starting materials using isolated urease.
FILED Tuesday, October 28, 2014
APPL NO 15/029866
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/002 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 11/18 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/42 (20130101)
C02F 1/286 (20130101)
C02F 1/5236 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 41/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/78 (20130101)
C12N 9/80 (20130101)

Enzymes
C12Y 305/01005 (20130101)

Foundations; Excavations; Embankments; Underground or Underwater Structures
E02D 3/12 (20130101) Original (OR) Class
E02D 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 10722921 Stratton et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Christopher M. Stratton (Springfield, Virginia);  Gregory J. Smith (Arlington, Virginia);  Thomas C. Potter (Oak Hill, Virginia)
ABSTRACT Sorting systems and methods for large quantities of items in industrial processes are described. The systems, devices and methods are for receiving, sorting and removing items dynamically. A first group of items, such as letters or other mail pieces, are injected by a belt into a pocket to a form a first stack, and a divider is extended near the first stack. The divider allows for a second group of items to either be injected to form a second stack behind the divider, or to be diverted and injected into another pocket. The first stack can be removed while the second group is being injected.
FILED Friday, November 08, 2019
APPL NO 16/678414
ART UNIT 3659 — Material and Article Handling
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/00 (20130101)
B07C 3/02 (20130101)
B07C 3/06 (20130101)
B07C 3/008 (20130101)
B07C 3/18 (20130101)
B07C 3/087 (20130101) Original (OR) Class
B07C 5/00 (20130101)
B07C 5/04 (20130101)
B07C 5/38 (20130101)

Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables
B65H 43/00 (20130101)
B65H 2301/43 (20130101)
B65H 2301/432 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10723577 Brown et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) John W. Brown (Manassas, Virginia);  Edward F. Houston (Bristow, Virginia);  Juan A. Roman (Fairfax, Virginia);  Leung M. Shiu (Gaithersburg, Maryland);  Riley Houston Mayhall, III (Gaithersburg, Maryland);  William P. McConnell (Woodstock, Maryland);  Matthew G. Good (Marriottsville, Maryland);  Robert E. Hume (Granite, Maryland);  Thomas A. Hillerich, Jr. (Louisville, Kentucky);  Long K. Ha (Frederick, Maryland)
ABSTRACT Embodiments of a system and method for singulating articles in an automatic stack feeder are disclosed. The automatic stack feeder may comprise a pressure sensor on a perforated drive belt assembly configured to sense the pressure exerted by a stack of articles. The sensed pressure may be used to control various portions of the automatic stack feeder, such as a belt or a paddle.
FILED Tuesday, July 03, 2018
APPL NO 16/026652
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables
B65H 1/025 (20130101)
B65H 3/124 (20130101) Original (OR) Class
B65H 2511/214 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10726532 Bovik et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Alan Bovik (Austin, Texas);  Todd Goodall (Austin, Texas)
ABSTRACT A method, system and computer program product for measuring non-uniformity noise produced in images or videos (e.g., infrared images or videos). Images or videos, such as infrared images or videos, are captured. A model of scene statistics (statistical model of pictures, images or videos representative of pictures, images or videos, respectively, that are captured of the physical world) is utilized to measure the non-uniformity noise in the captured images or videos by exploiting exhibited characteristics for non-uniformity noise in the captured images or videos. A number signifying a magnitude of non-uniformity for each image or video frame is then generated. In this manner, non-uniformity noise produced in images or videos is measured.
FILED Wednesday, August 31, 2016
APPL NO 15/758631
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 7/0002 (20130101) Original (OR) Class
G06T 2207/10016 (20130101)
G06T 2207/10048 (20130101)
G06T 2207/20072 (20130101)
G06T 2207/30168 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10724097 Patel
FUNDED BY
Department of Veterans Affairs (DVA)
National Science Foundation (NSF)
Office of The Director (OD)
Office of General Counsel(OGC)
APPLICANT(S) University of South Florida (Tampa, Florida);  THE U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF GENERAL COUNSEL (Washington, District of Columbia)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  The United States Government as Represented by the Department of Veterans Affairs Office of General Counsel (Washington, District of Columbia)
INVENTOR(S) Niketa A. Patel (Land O'Lakes, Florida)
ABSTRACT Described herein are assays, methods, and devices for diagnosing/prognosing diabetes, metabolic syndrome, pre-diabetic state and/or the early-onset of diabetes in a subject. The assays, methods, and devices described herein can be configured to detect one or more long-coding RNAs in a sample from a subject.
FILED Monday, November 30, 2015
APPL NO 15/528894
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 10721936 White, Jr. et al.
FUNDED BY
Department of the Interior (DOI)
U.S. Geological Survey (USGS)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey);  UNITED STATES GEOLOGICAL SURVEY (Reston, Virginia)
ASSIGNEE(S) Rutgers, The State University of NJ (New Brunswick, New Jersey);  United States Geological Survey (Reston, Virginia)
INVENTOR(S) James F. White, Jr. (South River, New Jersey);  Kurt P. Kowalski (Ann Arbor, Michigan);  Kathryn Kingsley (Robbinsville, New Jersey)
ABSTRACT Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which increase the root and shoot growth of grass hosts, suppress growth of soil borne fungal pathogens of host plants, increase resistance of the grass to diseases and reduce competitiveness of distantly related competitor weeds of the crop.
FILED Friday, July 21, 2017
APPL NO 15/657100
ART UNIT 1662 — Plants
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/00 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 1/01 (20130101)
C12R 1/38 (20130101)
C12R 1/39 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10727192 Abraham et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David W. Abraham (Croton, New York);  John M. Cotte (New Fairfield, Connecticut)
ABSTRACT A semiconductor structure and methods for the creation of solder bumps configured to carry a signal and solder bumps configured for ground planes and/or mechanical connections as well as methods for increasing reliability of a chip package generally include formation of multiple sized bump bonds on under bump metallization patterns and/or pads of the same dimension. The signal carrying solder bumps are larger in terms of diameter and bump height than solder bumps configured for ground plane and/or mechanical connections.
FILED Wednesday, November 15, 2017
APPL NO 15/813760
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/50 (20130101)
H01L 23/488 (20130101)
H01L 24/05 (20130101)
H01L 24/09 (20130101)
H01L 24/11 (20130101)
H01L 24/13 (20130101)
H01L 24/14 (20130101)
H01L 24/17 (20130101) Original (OR) Class
H01L 2224/061 (20130101)
H01L 2224/061 (20130101)
H01L 2224/114 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/0345 (20130101)
H01L 2224/0401 (20130101)
H01L 2224/1141 (20130101)
H01L 2224/1141 (20130101)
H01L 2224/1145 (20130101)
H01L 2224/1145 (20130101)
H01L 2224/1147 (20130101)
H01L 2224/1403 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/03462 (20130101)
H01L 2224/05022 (20130101)
H01L 2224/05124 (20130101)
H01L 2224/05124 (20130101)
H01L 2224/05147 (20130101)
H01L 2224/05147 (20130101)
H01L 2224/05572 (20130101)
H01L 2224/05572 (20130101)
H01L 2224/05666 (20130101)
H01L 2224/05666 (20130101)
H01L 2224/11452 (20130101)
H01L 2224/11452 (20130101)
H01L 2224/11462 (20130101)
H01L 2224/11462 (20130101)
H01L 2224/11472 (20130101)
H01L 2224/11849 (20130101)
H01L 2224/11901 (20130101)
H01L 2224/11901 (20130101)
H01L 2224/13005 (20130101)
H01L 2224/13006 (20130101)
H01L 2224/13007 (20130101)
H01L 2224/13022 (20130101)
H01L 2224/13111 (20130101)
H01L 2224/13111 (20130101)
H01L 2224/13116 (20130101)
H01L 2224/13116 (20130101)
H01L 2224/14104 (20130101)
H01L 2224/14104 (20130101)
H01L 2224/14517 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/013 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/0105 (20130101)
H01L 2924/207 (20130101)
H01L 2924/01082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 10722644 Green et al.
FUNDED BY
Non-Profit Organization (NPO)
California Institute for Regenerative Medicine (CIRM)
U.S. State Government
State of California
APPLICANT(S) ViaCyte, Inc. (San Diego, California)
ASSIGNEE(S) Viacyte, Inc. (San Diego, California)
INVENTOR(S) Chad Green (San Diego, California);  Laura Martinson (San Diego, California);  Erik Olson (San Diego, California);  Val Anthony Bellora (San Diego, California);  Leah Elliott (San Diego, California);  Richard Alexander Grant (San Diego, California);  Donald Koenig (San Diego, California);  Giacomo Strollo (San Diego, California)
ABSTRACT Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.
FILED Thursday, November 20, 2014
APPL NO 15/528731
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/022 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/142 (20130101)
A61M 5/14276 (20130101) Original (OR) Class
A61M 37/0069 (20130101)
A61M 2209/045 (20130101)

Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking
B65B 3/003 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10724142 Masel et al.
FUNDED BY
APPLICANT(S) Dioxide Materials, Inc. (Boca Raton, Florida)
ASSIGNEE(S) Dioxide Materials, Inc. (Boca Raton, Florida)
INVENTOR(S) Richard I. Masel (Boca Raton, Florida);  Zengcai Liu (Boca Raton, Florida)
ABSTRACT Water electrolyzers employs base metal catalysts and an anion-conducting polymeric membrane with an area specific resistance at 60° C. in 1 M KOH below 0.037 ohm-cm2. Preferably, the membrane comprising a polymer of styrene, vinylbenzyl-Rs and possibly vinylbenzyl-Rx. Rs is a positively charged cyclic amine group. Rx is at least one constituent selected from the group consisting of —Cl, —OH, and a reaction product between an —OH or —Cl and a species other than a simple amine or a cyclic amine.
FILED Monday, April 30, 2018
APPL NO 15/967293
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/469 (20130101)
C02F 1/46104 (20130101)
C02F 1/46109 (20130101)
C02F 2001/46142 (20130101)
C02F 2201/46115 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/10 (20130101) Original (OR) Class
C25B 9/10 (20130101)
C25B 13/08 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/1023 (20130101)
H01M 8/1067 (20130101)
H01M 2008/1095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10724436 Mayer et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jeffrey Carl Mayer (Swampscott, Massachusetts);  Apostolos Pavlos Karafillis (Winchester, Massachusetts);  John Alan Manteiga (North Andover, Massachusetts);  Courtney Ann Kiszewski (Ipswich, Massachusetts);  Kyle Earl Roland Henry (Seabrook, New Hampshire);  Craig Douglas Young (Blanchester, Ohio)
ABSTRACT A method and apparatus for separating particles from an inlet airflow of a turbine engine has a centerbody with a radially outer scavenge conduit. The inlet airflow has entrained particulate matter, which can impact an impact surface defining part of the centerbody. The impact surface can be disposed at an angle or have a low coefficient of restitution to reduce the velocity of the incoming particulate matter. The particulate matter is radially diverted radially outward through the scavenge conduit, unable to make a turn defined by the shape of the centerbody.
FILED Thursday, January 21, 2016
APPL NO 15/002839
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Separation
B01D 45/00 (20130101)
B01D 45/06 (20130101)
B01D 45/08 (20130101)
B01D 45/16 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/052 (20130101) Original (OR) Class
F02C 7/055 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/607 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10726090 Compton et al.
FUNDED BY
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Ryan F. Compton (Los Angeles, California);  David L. Allen (Thousand Oaks, California)
ABSTRACT Described is a system for geocoding social networks by minimizing total variation. A set of social media data from a social media platform having users is received. A social network is generated from the set of social media data based on communication between users. A ground truth set of locations is determined for users who make their locations public, and the ground truth set of locations is propagated across the social network to generate a location estimate for each user. A confidence measure for each location estimate is then generated.
FILED Wednesday, November 12, 2014
APPL NO 14/539828
ART UNIT 2163 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/22 (20190101)
G06F 16/29 (20190101)
G06F 16/955 (20190101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/1831 (20130101)
H04L 67/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727162 Loney et al.
FUNDED BY
APPLICANT(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Patrick Loney (Fairview Park, Ohio);  Robert Miles Young (Ellicott City, Maryland);  Daniel Robert Queen (Kensington, Maryland);  Aaron Ashley Hathaway (Baltimore, Maryland);  John X. Przybysz (Severna Park, Maryland)
ABSTRACT An integrated circuit is provided that comprises a thermal sink layer, a first ground plane associated with a first set of circuits that have a first operational temperature requirement, and a first thermally conductive via that couples the first ground plane to the thermal sink layer. The circuit further comprises a second ground plane associated with a second set of circuits that have a second operational temperature requirement that is higher than the first operational temperature requirement, and a second thermally conductive via that couples the second ground plane to the thermal sink layer, wherein the first thermally conductive via has a greater volume of thermal conductive material than the second thermally conductive via to remove heat from the first set of circuits with less gradient than the second set of circuits.
FILED Monday, January 07, 2019
APPL NO 16/241629
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/3677 (20130101)
H01L 23/3736 (20130101)
H01L 23/4334 (20130101) Original (OR) Class
H01L 23/49888 (20130101)
H01L 27/18 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0204 (20130101)
H05K 1/0207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10727391 Abraham et al.
FUNDED BY
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David W. Abraham (Croton, New York);  John M. Cotte (New Fairfield, Connecticut);  Mary B. Rothwell (Ridgefield, Connecticut)
ABSTRACT A technique relates to a device. First thin films are characterized by having a first opposing surface and a first connection surface in which the first connection surface is in physical contact with a first superconducting region. Second thin films are characterized by having a second opposing surface and a second connection surface in which the first and second opposing surfaces are opposite one another. The second connection surface is in physical contact with a second superconducting region. A solder material electrically connects the first and second opposing surfaces, and the solder material is characterized by maintaining a low ohmic electrical contact between the first and second opposing surfaces at temperatures below 100 degrees Kelvin. The first and second superconducting regions are formed of materials that have a melting point of at least 700 degrees Celsius.
FILED Friday, September 29, 2017
APPL NO 15/721087
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/473 (20130101)
H01L 23/49888 (20130101)
H01L 24/03 (20130101)
H01L 24/05 (20130101)
H01L 24/11 (20130101)
H01L 24/13 (20130101)
H01L 24/16 (20130101)
H01L 24/81 (20130101)
H01L 39/02 (20130101) Original (OR) Class
H01L 39/12 (20130101)
H01L 39/223 (20130101)
H01L 39/2406 (20130101)
H01L 39/2493 (20130101)
H01L 2224/0381 (20130101)
H01L 2224/0401 (20130101)
H01L 2224/1181 (20130101)
H01L 2224/1308 (20130101)
H01L 2224/05023 (20130101)
H01L 2224/05111 (20130101)
H01L 2224/05111 (20130101)
H01L 2224/05173 (20130101)
H01L 2224/05173 (20130101)
H01L 2224/05176 (20130101)
H01L 2224/05176 (20130101)
H01L 2224/05179 (20130101)
H01L 2224/05568 (20130101)
H01L 2224/05583 (20130101)
H01L 2224/05609 (20130101)
H01L 2224/05609 (20130101)
H01L 2224/05639 (20130101)
H01L 2224/05644 (20130101)
H01L 2224/05647 (20130101)
H01L 2224/05664 (20130101)
H01L 2224/05664 (20130101)
H01L 2224/05666 (20130101)
H01L 2224/05669 (20130101)
H01L 2224/05669 (20130101)
H01L 2224/05671 (20130101)
H01L 2224/05673 (20130101)
H01L 2224/05673 (20130101)
H01L 2224/05676 (20130101)
H01L 2224/05684 (20130101)
H01L 2224/13023 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13111 (20130101)
H01L 2224/13113 (20130101)
H01L 2224/13116 (20130101)
H01L 2224/13139 (20130101)
H01L 2224/13147 (20130101)
H01L 2224/16014 (20130101)
H01L 2224/16148 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/81801 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/0105 (20130101)
H01L 2924/0105 (20130101)
H01L 2924/201 (20130101)
H01L 2924/01083 (20130101)
H01L 2924/01083 (20130101)
H01L 2924/2064 (20130101)
H01L 2924/20104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 28, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200728.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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