FedInvent™ Patents

Patent Details for Tuesday, September 22, 2020 

This page was updated on Monday, March 27, 2023 at 06:11 AM GMT

Department of Health and Human Services (HHS) 

US 10779517 McCarthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Cullen McCarthy (Oklahoma City, Oklahoma);  William Berry (Edmond, Oklahoma);  James Tomasek (Oklahoma City, Oklahoma);  Jason Lees (Edmond, Oklahoma)
ABSTRACT A non-human animal model, method, spring, and kit for testing agents for treating wound scarring. The non-human test animal has a wound in a skin surface thereof, the wound having a perimeter edge; and a garter spring attached to the skin surface of the test animal in a position outside of the perimeter edge of the wound. The garter spring optionally has one or more bands for constricting the force exerted by the coil of the garter spring.
FILED Tuesday, January 30, 2018
APPL NO 16/068492
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/02 (20130101) Original (OR) Class
A01K 67/027 (20130101)
A01K 2207/30 (20130101)
A01K 2227/105 (20130101)
A01K 2267/03 (20130101)

Diagnosis; Surgery; Identification
A61B 17/0293 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779730 Durand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Dominique M. Durand (Solon, Ohio);  Brian Wodlinger (Pittsburgh, Pennsylvania)
ABSTRACT A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel.
FILED Wednesday, January 10, 2018
APPL NO 15/866884
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/00 (20130101) Original (OR) Class
A61B 5/0488 (20130101)
A61B 5/686 (20130101)
A61B 5/4052 (20130101)
A61B 5/4851 (20130101)
A61B 5/6877 (20130101)
A61B 5/6887 (20130101)
A61B 2505/09 (20130101)
A61B 2562/043 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2002/482 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0556 (20130101)
A61N 1/36125 (20130101)
A61N 1/36135 (20130101)
A61N 1/36167 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779732 Aho et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mayo Foundation For Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Johnathon M. Aho (Rochester, Minnesota);  Dennis A. Wigle (Rochester, Minnesota);  Matthew W. Urban (Rochester, Minnesota)
ABSTRACT A system and method is provided for measuring a mechanical property of a biological tube. The system and method operate to arrange a plurality of piezoelectric elements about the biological tube and apply a predetermined force or transduce an endogeneous or exogeneous force to the biological tube. The system and method also operate to receive a respective signal from each piezoelectric element in the plurality of piezoelectric elements responsive to the application of the predetermined force or a transduced endogenous or exogeneous force and calculate the mechanical property of the biological tube based on the signals received from the plurality of piezoelectric elements.
FILED Wednesday, March 22, 2017
APPL NO 15/466227
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/42 (20130101)
A61B 5/0053 (20130101) Original (OR) Class
A61B 5/687 (20130101)
A61B 5/02007 (20130101)
A61B 5/4233 (20130101)
A61B 5/6876 (20130101)
A61B 5/7271 (20130101)
A61B 2562/0261 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2203/0089 (20130101)
G01N 2203/0274 (20130101)
G01N 2203/0623 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779746 Even-Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Nir Even-Chen (Palo Alto, California);  Krishna V. Shenoy (Palo Alto, California);  Jonathan C. Kao (Los Angeles, California);  Sergey Stavisky (San Francisco, California)
ABSTRACT A brain machine interface (BMI) for improving a performance of a subject is provided. The BMI has two decoders that act in real-time and in parallel to each other. The first decoder is for intention execution of a subject's intention. The second decoder is for error detection in a closed-loop error fashion with the first detector and to improve the performance of the first detector. Embodiments of this invention may enable an entirely new way to substantially increase the performance and robustness, user experience, and ultimately the clinical viability of BMI systems.
FILED Thursday, August 11, 2016
APPL NO 15/234844
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0482 (20130101) Original (OR) Class
A61B 5/04012 (20130101)
A61B 5/7267 (20130101)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
G06N 20/20 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779762 Yablonskiy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Washington University in St. Louis (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Dmitriy Yablonskiy (Olivette, Missouri);  Yue Zhao (St. Louis, Missouri)
ABSTRACT Disclosed are systems, biomarkers, and methods for the diagnosis of Alzheimer's Disease.
FILED Wednesday, October 19, 2016
APPL NO 15/770127
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/4088 (20130101) Original (OR) Class
A61B 5/14542 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/5601 (20130101)
G01R 33/5608 (20130101)
G01R 33/5616 (20130101)
G01R 33/56366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779765 Bly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Aclaris Medical, LLC (Falcon Heights, Minnesota)
ASSIGNEE(S) Aclaris Medical, LLC (Falcon Heights, Minnesota)
INVENTOR(S) Mark Bly (Falcon Heights, Minnesota);  Andrew Radtke (Minneapolis, Minnesota)
ABSTRACT The disclosure includes a system for sensing physiologic data. The system can include a flexible configured to wrap around a finger of a user, a first electrode coupled to the flexible strap, and a second electrode coupled to the flexible strap. The system can also include a sensor housing comprising at least one sensor configured to detect physiologic data from the finger and a data receiving module communicatively coupled to the first electrode, the second electrode, and the at least one sensor. The data receiving module can be configured to receive physiologic data from the at least one sensor.
FILED Monday, September 26, 2016
APPL NO 15/276169
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0024 (20130101)
A61B 5/029 (20130101)
A61B 5/0408 (20130101)
A61B 5/0531 (20130101)
A61B 5/0816 (20130101)
A61B 5/1118 (20130101)
A61B 5/02055 (20130101)
A61B 5/02108 (20130101)
A61B 5/02405 (20130101)
A61B 5/02438 (20130101)
A61B 5/6826 (20130101) Original (OR) Class
A61B 5/6831 (20130101)
A61B 5/14542 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779799 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Shigao Chen (Rochester, Minnesota);  James Greenleaf (Rochester, Minnesota);  Daniel C. Mellema (Rochester, Minnesota);  Pengfei Song (Rochester, Minnesota)
ABSTRACT A method for imaging an object by ultrasound elastography through continuous vibration of the ultrasound transducer is taught. An actuator directly in contact with the ultrasound transducer continuously vibrates the transducer in an axial direction, inducing shear waves in the tissue and allowing for real-time shear wave imaging. Axial motion of the transducer contaminates the shear wave images of the tissue, and must be suppressed. Therefore, several methods for correcting for shear wave artifact caused by the motion of the transducer are additionally taught.
FILED Wednesday, October 28, 2015
APPL NO 15/522067
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0051 (20130101)
A61B 8/14 (20130101)
A61B 8/485 (20130101)
A61B 8/4444 (20130101)
A61B 8/4483 (20130101)
A61B 8/5207 (20130101) Original (OR) Class
A61B 8/5269 (20130101)
A61B 8/5276 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/52022 (20130101)
G01S 7/52042 (20130101)
G01S 7/52077 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779964 Raaz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Board of Trustees of the Leland Stanford Junior University (Palo Alto, California);  VA Palo Alto Health Care System (Palo Alto, California)
INVENTOR(S) Uwe Raaz (Gottingen, Germany);  Isabel N. Schellinger (Gottingen, Germany);  Joshua M. Spin (San Jose, California);  Philip S. Tsao (Los Altos, California)
ABSTRACT Methods, compositions, and devices for treating a vascular aneurysm, including an abdominal aortic aneurysm, are disclosed. In particular, the various embodiments relate to a method of treating an abdominal aortic aneurysm by increasing the mechanical stiffness of an aortic segment adjacent to the abdominal aortic aneurysm in a subject. The mechanical stiffness of the adjacent aortic segment may be increased, for example, by applying a surgical adhesive or intravascular stent. Such treatment reduces stress on the aortic wall and limits further growth of the abdominal aortic aneurysm.
FILED Tuesday, March 15, 2016
APPL NO 15/070817
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00491 (20130101)
A61B 2017/00778 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/82 (20130101) Original (OR) Class
A61F 2/90 (20130101)
A61F 2002/823 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780045 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Wenbin Lin (Chicago, Illinois);  Chunbai He (Chicago, Illinois);  Kuangda Lu (Chicago, Illinois)
ABSTRACT Metal-organic frameworks (MOFs) comprising photosensitizers are described. The MOFs can also include moieties capable of absorbing X-rays and/or scintillation. Optionally, the photosensitizer or a derivative thereof can form a bridging ligand of the MOF. Further optionally, the MOF can comprise inorganic nanoparticles in the cavities or channels of the MOF or can be used in combination with an inorganic nanoparticle. Also described are methods of using MOFs and/or inorganic nanoparticles in photodynamic therapy or in X-ray induced photodynamic therapy, either with or without the co-administration of one or more immunotherapeutic agent and/or one or more chemotherapeutic agent.
FILED Friday, December 28, 2018
APPL NO 16/235752
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101) Original (OR) Class
A61K 31/282 (20130101)
A61K 31/337 (20130101)
A61K 31/405 (20130101)
A61K 31/409 (20130101)
A61K 31/519 (20130101)
A61K 31/704 (20130101)
A61K 31/4188 (20130101)
A61K 31/4745 (20130101)
A61K 41/0038 (20130101)
A61K 41/0057 (20130101)
A61K 41/0071 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780069 Monga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Università degli Studi di Cagliari (Cagliari, Italy)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Universitá degli Studi di Cagliari (Cagliari, Italy)
INVENTOR(S) Satdarshan Pal Singh Monga (Wexford, Pennsylvania);  Amedeo Columbano (Selargius, Italy)
ABSTRACT Methods are disclosed for the use of GC-1 (sobetirome), a prodrug thereof, or a pharmaceutically acceptable salt or prodrug thereof to increase liver regeneration and healing in liver transplant donors and recipients.
FILED Tuesday, May 15, 2018
APPL NO 15/980645
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/192 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780076 Bergan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Raymond C. Bergan (Chicago, Illinois);  Karl A. Scheidt (Evanston, Illinois);  Li Xu (Evanston, Illinois)
ABSTRACT Provided herein are compositions and methods for inhibiting cancer cell motility and/or metastasis. In particular embodiments, KBU2046 (or an analog thereof) and one or more additional therapies (e.g., cancer therapies (e.g., hormone therapies and chemotherapies) are provided to inhibit cancer cell motility, inhibit metastasis, and/or treat cancer (e.g., prostate cancer, lung cancer, breast cancer, colon cancer, etc.).
FILED Tuesday, March 19, 2019
APPL NO 16/358233
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/353 (20130101) Original (OR) Class
A61K 31/353 (20130101)
A61K 31/4188 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780078 Shoichet et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California);  FRIEDRICH-ALEXANDER-UNIVERSITÄT ERLANGEN-NÜRNBERG (Erlangen, Germany)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  FRIEDRICH-ALEXANDER-UNIVERSITÄT (Erlangen, Germany);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S) Brian K. Shoichet (Kentfield, California);  Anat Levit (San Francisco, California);  Aashish Manglik (Menlo Park, California);  Brian Kobilka (Palo Alto, California);  Peter Gmeiner (Erlangen, Germany);  Harald Hübner (Heroldsbach, Germany);  Daniela Gisela Dengler (Erlangen, Germany)
ABSTRACT Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
FILED Friday, August 17, 2018
APPL NO 16/104803
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/381 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/04 (20180101)
A61P 25/22 (20180101)
A61P 25/24 (20180101)
A61P 25/36 (20180101)

Acyclic or Carbocyclic Compounds
C07C 225/20 (20130101)
C07C 275/24 (20130101)
C07C 2601/04 (20170501)
C07C 2602/08 (20170501)
C07C 2602/12 (20170501)

Heterocyclic Compounds
C07D 333/20 (20130101)
C07D 333/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780084 Spiegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut);  KLEO PHARMACEUTICALS, INC. (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut);  KLEO PHARMACEUTICALS, INC. (New Haven, Connecticut)
INVENTOR(S) David Spiegel (New Haven, Connecticut);  H. Marie Loughran (Perkasie, Pennsylvania);  Jeffrey C. Pelletier (Lafayette Hill, Pennsylvania);  Allen B. Reitz (Lansdale, Pennsylvania);  Matthew Ernest Welsch (New Haven, Connecticut)
ABSTRACT The present invention relates to chimeric (including bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic and other cancers where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells. The compounds bind to the urokinase-type plasminogen activator receptor (uPAR) on the surface of a cancer cell, including a metastatic cancer cell, and consequently recruit native antibodies of the patient or subject where the antibodies can selectively degrade and/or deactivate targeted cancer cells through antibody-dependent cellular phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) against a large number and variety of cancers, thus providing cancer cell death and an inhibition of growth, elaboration and/or metastasis of the cancer, including remission and cure of the patient's cancer.
FILED Thursday, August 03, 2017
APPL NO 16/322391
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/454 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/55 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/02 (20180101)
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 211/26 (20130101)
C07D 211/62 (20130101)
C07D 261/20 (20130101)
C07D 413/04 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780094 Fossati
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Silvia Fossati (Long Island City, New York)
ABSTRACT The invention is directed to the use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders.
FILED Friday, July 21, 2017
APPL NO 15/657022
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/18 (20130101)
A61K 31/357 (20130101)
A61K 31/382 (20130101)
A61K 31/404 (20130101)
A61K 31/415 (20130101)
A61K 31/423 (20130101)
A61K 31/428 (20130101)
A61K 31/433 (20130101)
A61K 31/542 (20130101)
A61K 31/549 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/16 (20180101)
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780095 Zhou
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Qun-Yong Zhou (Irvine, California)
ABSTRACT In alternative embodiments, provided are methods for: modifying circadian rhythmicity or timing in a mammal, treating psychiatric conditions or symptoms due to alterations in a human circadian regulatory system, treating sleep problems in a mammal, or inducing sleep or activity suppression, or causing an arousal or wakening reaction, comprising administration to a mammal or human a compound or composition capable of modifying a prokineticin 2 (PK2) expression or activity, and/or a PKR2 (PK2 receptor), a vasopressin receptor (VR), and/or a melatonin receptor (MR) expression or activity.
FILED Thursday, April 06, 2017
APPL NO 16/090044
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/0048 (20130101)
A61K 31/357 (20130101)
A61K 31/454 (20130101)
A61K 31/4025 (20130101)
A61K 31/4184 (20130101)
A61K 31/5377 (20130101)
A61K 31/5513 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/18 (20180101)
A61P 25/24 (20180101)
A61P 29/00 (20180101)
A61P 35/00 (20180101)
A61P 37/06 (20180101)

Heterocyclic Compounds
C07D 321/10 (20130101)
C07D 405/12 (20130101)
C07D 413/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780104 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S)
INVENTOR(S) Jin Q. Cheng (Tampa, Florida);  Said M. Sebti (Tampa, Florida)
ABSTRACT This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
FILED Friday, April 14, 2017
APPL NO 15/487843
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/517 (20130101)
A61K 31/5377 (20130101)
A61K 31/7064 (20130101) Original (OR) Class
A61K 31/7068 (20130101)
A61K 31/7076 (20130101)
A61K 45/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57426 (20130101)
G01N 2333/912 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780118 Jensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Fred Hutchinson Cancer Research Center (Seattle, Washington);  Seattle Children's Hospital (Seattle, Washington)
ASSIGNEE(S) Fred Hutchinson Cancer Research Center (Seattle, Washington);  Seattle Children's Hospital (Seattle, Washington)
INVENTOR(S) Michael C. Jensen (Bainbridge Island, Washington);  Stanley R. Riddell (Sammamish, Washington);  Michael Hudecek (Leipzig, Germany)
ABSTRACT The present invention provides nucleic acids, vectors, host cells, methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring CD8+ central memory T cells or combinations of central memory T cells with CD4+ T cells that are genetically modified to express a chimeric receptor. In embodiments the genetically modified host cell comprises a nucleic acid comprising a polynucleotide coding for a ligand binding domain, a polynucleotide comprising a customized spacer region, a polynucleotide comprising a transmembrane domain, and a polynucleotide comprising an intracellular signaling domain. It has been surprisingly found that the length of the spacer region can affects the ability of chimeric receptor modified T cells to recognize target cells in vitro and affects in vivo efficacy of the chimeric receptor modified T cells. Pharmaceutical formulations produced by the method, and methods of using the same, are also described.
FILED Tuesday, August 20, 2013
APPL NO 14/422640
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class

Peptides
C07K 14/705 (20130101)
C07K 14/7051 (20130101)
C07K 14/7151 (20130101)
C07K 14/70521 (20130101)
C07K 16/32 (20130101)
C07K 16/40 (20130101)
C07K 16/2803 (20130101)
C07K 2317/64 (20130101)
C07K 2317/622 (20130101)
C07K 2319/03 (20130101)
C07K 2319/30 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780131 Kriegstein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Arnold Kriegstein (Mill Valley, California);  John L. R. Rubenstein (San Francisco, California);  Scott C. Baraban (Novato, California);  Arturo Alvarez-Buylla (Woodside, California)
ABSTRACT The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic interneurons at or near the site of the neurological disease, injury, or condition.
FILED Thursday, September 27, 2018
APPL NO 16/144786
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0085 (20130101)
A61K 35/30 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0618 (20130101)
C12N 5/0622 (20130101)
C12N 2506/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/28 (20130101)
G01N 2800/2835 (20130101)
G01N 2800/2842 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780147 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Los Angeles, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Steven M. Dubinett (Los Angeles, California);  Sherven Sharma (Oakland, California);  Upendra K. Kar (Oakland, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
FILED Friday, February 03, 2017
APPL NO 15/424654
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 47/6921 (20170801)
A61K 48/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/521 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/96 (20130101)
C12N 9/1077 (20130101)
C12N 15/86 (20130101)

Enzymes
C12Y 204/0203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780150 Krauss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S) Isaac J. Krauss (Waltham, Massachusetts);  Joel Sebastian Temme (Waltham, Massachusetts)
ABSTRACT Disclosed are oligonucleotides that binds specifically to HIV neutralizing monoclonal antibody 2G12 with a K4 value lower than 20 nM, the oligonucleotide comprising a predicted structure, at 37° C., having exactly one stem-loop whereby the loop comprises the nucleotide sequence of AACCNACGGANAAA (SEQ ID NO: 1), where N is a modified nucleoside base, and the stem includes at least 3 nucleotide base-pairs and one of the nucleotides in the stem includes a modified nucleoside base, wherein the modified nucleoside base has the structure -B-L-A where A is a branched-chain Man9 oligosaccharide, L is a linker molecule, and B is independently a pyrimidine or pyridine base linked to the sugar-phosphate backbone of the oligonucleotide. Immunogenic conjugates that include the oligonucleotide, and pharmaceutical compositions that include the oligonucleotide or the immunogenic conjugate are also disclosed. Various method of using the oligonucleotides, immunogenic conjugates, and pharmaceutical compositions are also disclosed.
FILED Thursday, April 06, 2017
APPL NO 16/092137
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0005 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 2039/51 (20130101)
A61K 2039/545 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/22 (20130101)
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/115 (20130101)
C12N 15/117 (20130101)
C12N 2310/13 (20130101)
C12N 2310/16 (20130101)
C12N 2310/351 (20130101)
C12N 2320/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780153 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) GenVec, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) GenVec, Inc. (Gaithersburg, Maryland)
INVENTOR(S) Ping Chen (Potomac, Maryland);  Duncan McVey (Derwood, Maryland);  Douglas E. Brough (Gaithersburg, Maryland);  Joseph Bruder (Gaithersburg, Maryland)
ABSTRACT The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
FILED Wednesday, April 24, 2019
APPL NO 16/393035
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/015 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/5256 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/412 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780155 Nizet et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Victor Nizet (San Diego, California);  Nina van Sorge (Utrecht, Netherlands)
ABSTRACT In alternative embodiments, the invention provides vaccines, pharmaceutical compounds and formulations for diagnosing, preventing, treating or ameliorating Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections. In alternative embodiments, the invention provides compositions such as diagnostic tests, assays, immunoassays and test strips, and methods, for detecting or diagnosing the presence of a Streptococcal infection, e.g., Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections.
FILED Wednesday, September 14, 2016
APPL NO 15/265800
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/092 (20130101) Original (OR) Class
A61K 2039/522 (20130101)
A61K 2039/552 (20130101)

Peptides
C07K 14/315 (20130101)
C07K 16/44 (20130101)
C07K 16/1275 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/0006 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 1/36 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5308 (20130101)
G01N 33/56938 (20130101)
G01N 33/56944 (20130101)
G01N 2400/02 (20130101)
G01N 2500/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780178 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Jiang Zhu (San Diego, California);  Linling He (San Diego, California)
ABSTRACT The present invention provides novel scaffolded HIV-1 vaccine immunogens. Some of the scaffolded immunogens contain a soluble gp140 trimer linked to the N-terminus of the nanoparticle subunit and a T-helper epitope that is fused via a short peptide spacer to the C-terminus of the nanoparticle subunit. Some other immunogens of the invention contain a soluble gp140 trimer protein that is linked to a stable nanoparticle via a short peptide spacer that is a T-helper epitope. Some of the scaffolded immunogens contain a gp140 trimer immunogen presented on a nanoparticle platform formed with I3-01 protein, E2p, or variants of protein 1VLW. Also provided in the invention are nucleic acids that encode the various vaccine immunogens described herein, and expression vectors and host cells harboring the nucleic acids. The invention further provides methods of using the scaffolded HIV-1 vaccine immunogens for preventing or treating HIV infections.
FILED Wednesday, October 31, 2018
APPL NO 16/177165
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 38/162 (20130101)
A61K 39/12 (20130101)
A61K 39/21 (20130101)
A61K 47/69 (20170801)
A61K 47/646 (20170801) Original (OR) Class
A61K 2039/57 (20130101)
A61K 2039/575 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55561 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/162 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16023 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780272 McMahon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Matthew J. McMahon (Los Angeles, California);  Arup Roy (Santa Clarita, California);  Scott Greenwald (Seattle, Washington);  Ione Fine (Seattle, Washington);  Alan Matthew Horsager (Los Angeles, California);  Avraham I. Caspi (La Jolla, California);  Kelly Hobart McClure (Simi Valley, California);  Robert Jay Greenberg (Los Angeles, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California);  Doheny Eye Institute (Los Angeles, California)
INVENTOR(S) Matthew J. McMahon (Los Angeles, California);  Arup Roy (Santa Clarita, California);  Scott Greenwald (Seattle, Washington);  Ione Fine (Seattle, Washington);  Alan Matthew Horsager (Los Angeles, California);  Avraham I. Caspi (La Jolla, California);  Kelly Hobart McClure (Simi Valley, California);  Robert Jay Greenberg (Los Angeles, California)
ABSTRACT The present invention is a fitting system with a graphical interface with specific interface screens for specific functions. Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
FILED Monday, August 20, 2012
APPL NO 13/590011
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0543 (20130101)
A61N 1/36046 (20130101) Original (OR) Class
A61N 1/37247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780298 Cain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Charles A. Cain (Ann Arbor, Michigan);  Adam Maxwell (Seattle, Washington);  Zhen Xu (Ann Arbor, Michigan);  Kuang-Wei Lin (Ann Arbor, Michigan)
ABSTRACT Apparatus and methods are provided for applying ultrasound pulses into tissue or a medium in which the peak negative pressure (P−) of one or more negative half cycle(s) of the ultrasound pulses exceed(s) an intrinsic threshold of the tissue or medium, to directly form a dense bubble cloud in the tissue or medium without shock-scattering. In one embodiment, a microtripsy method of Histotripsy therapy comprises delivering an ultrasound pulse from an ultrasound therapy transducer into tissue, the ultrasound pulse having at least a portion of a peak negative pressure half-cycle that exceeds an intrinsic threshold in the tissue to produce a bubble cloud of at least one bubble in the tissue, and generating a lesion in the tissue with the bubble cloud. The intrinsic threshold can vary depending on the type of tissue to be treated. In some embodiments, the intrinsic threshold in tissue can range from 15-30 MPa.
FILED Friday, August 22, 2014
APPL NO 14/911273
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101) Original (OR) Class
A61N 2007/0039 (20130101)
A61N 2007/0065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781161 Shulman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Gerald I. Shulman (East Haven, Connecticut);  David A. Spiegel (New Haven, Connecticut)
ABSTRACT The present invention includes DNP derivatives that are useful for preventing or treating a metabolic disease or disorder in a subject in need thereof. In certain embodiments, the subject is further administered at least one additional therapeutic agent.
FILED Wednesday, May 22, 2019
APPL NO 16/419949
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/085 (20130101)

Acyclic or Carbocyclic Compounds
C07C 205/37 (20130101) Original (OR) Class

Steroids
C07J 41/0055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781183 Neamati et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  UNIVERSITÀ DEGLI STUDI DI SASSARI (Sassari, Italy)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  UNIVERSITA DEGLI STUDI DI SASSARI (Sassari, Italy)
INVENTOR(S) Nouri Neamati (Ann Arbor, Michigan);  Mario Sechi (Sassari, Italy)
ABSTRACT This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.
FILED Tuesday, March 07, 2017
APPL NO 16/083376
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 239/74 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 413/12 (20130101)
C07D 417/12 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781213 Stoltz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Brian M. Stoltz (San Marino, California);  Eric R. Welin (Pasadena, California);  Scott C. Virgil (Pasadena, California);  Pamela Tadross (Natick, Massachusetts);  Gerit M. Pototschnig (San Diego, California);  Aurapat (Fa) Ngamnithiporn (Pasadena, California);  Kenji Negoro (Ibaraki, Japan);  Guillaume Lapointe (Basel, Switzerland);  Max Klatte (Loerrach, Germany);  Christopher Haley (Boston, Massachusetts);  Christian Gruenanger (Mannheim, Germany);  Emil Glibstrup (Copenhagen, Denmark);  Christopher Gilmore (Natick, Massachusetts);  Kevin McCormack Allan (Belmont, California)
ABSTRACT (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.
FILED Friday, November 22, 2019
APPL NO 16/692518
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/04 (20130101)
C07D 471/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781237 Niederweis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The UAB Research Foundation (Birmingham, Alabama)
ASSIGNEE(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Michael Niederweis (Homewood, Alabama);  Mikhail Pavlenok (Birmingham, Alabama)
ABSTRACT Provided herein are mutant single-chain Mycobacterium smegmatis porin (Msp) and uses thereof.
FILED Thursday, April 16, 2015
APPL NO 15/304183
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/35 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2565/631 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44743 (20130101)
G01N 27/44756 (20130101)
G01N 33/48721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781240 Storkus et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Walter J. Storkus (Glenshaw, Pennsylvania);  Michael S. Kinch (Laytonsville, Maryland)
ABSTRACT EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as an ELISPOT assay, that may be used to determine and/or quantify a patient's immune responsiveness to EphA2. The epitopes also are useful in methods of modulating a patient's immune reactivity to EphA2, which has substantial utility as a treatment for cancers that overexpress EphA2, such as renal cell carcinoma (RCC). The EphA2 epitopes also can be used to vaccinate a patient against EphA2, by in vivo or ex vivo methods.
FILED Thursday, October 04, 2018
APPL NO 16/152242
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1793 (20130101)
A61K 39/0011 (20130101)
A61K 2039/55566 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)
C07K 14/47 (20130101)
C07K 14/705 (20130101)
C07K 14/4748 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/505 (20130101)
G01N 33/5091 (20130101)
G01N 33/56966 (20130101)
G01N 33/56972 (20130101)
G01N 2333/57 (20130101)
G01N 2333/5409 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781254 Noelle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Randolph J. Noelle (Plainfield, New Hampshire);  Lili Wang (Norwich, Vermont)
ABSTRACT The present invention relates to a novel regulatory T cell protein. This protein, designated PD-L3 OR VISTA resembles members of the PD-L1 family, identified a novel and structurally-distinct, Ig-superfamily inhibitory ligand, whose extracellular domain bears homology to the B7 family ligand PD-L1. This molecule is designated as PD-L3 OR VISTA or V-domain Immunoglobulin Suppressor of T cell Activation (VISTA). Expression of VISTA is primarily within the hematopoietic compartment and is highly regulated on myeloid APCs and T cells. Therapeutic intervention of the VISTA inhibitory pathway represents a novel approach to modulate T cell-mediated immunity for the treatment of a wide variety of cancers, e.g., ovarian, bladder cancer and melanomas. Also, VISTA proteins, especially multimeric VISTA proteins and antibodies may be used to suppress T cell immunity in autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis and artritic conditions such as RA.
FILED Thursday, March 23, 2017
APPL NO 15/467118
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 14/70503 (20130101)
C07K 16/28 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 2317/76 (20130101)
C07K 2319/30 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/41 (20180101)
Y02A 50/386 (20180101)
Y02A 50/412 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781294 Nash et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
INVENTOR(S) Landon D. Nash (Sunnyvale, California);  Duncan J. Maitland (College Station, Texas);  Nicole Docherty (Trop, Michigan);  Thomas S. Wilson (San Leandro, California);  Ward Small, IV (Livermore, California);  Jason Ortega (Pacifica, California);  Pooja Singhal (Redwood City, California)
ABSTRACT An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein.
FILED Friday, July 22, 2016
APPL NO 15/746471
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 24/0036 (20130101)
A61L 24/046 (20130101)
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/14 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)
A61L 2430/36 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/62 (20130101)
B05D 3/144 (20130101)
B05D 7/02 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/5663 (20130101)
B29C 59/14 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2033/04 (20130101)
B29K 2069/00 (20130101)
B29K 2075/00 (20130101)
B29K 2077/00 (20130101)
B29K 2995/0093 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/18 (20130101)
B32B 27/06 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/36 (20130101)
C08J 9/365 (20130101) Original (OR) Class
C08J 2201/026 (20130101)
C08J 2205/04 (20130101)
C08J 2207/10 (20130101)
C08J 2375/04 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781419 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Aberdeen Proving Ground (APG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanaria Inc. (Rockville, Maryland);  Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Sanaria Inc. (Rockville, Maryland);  Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Russell H. Taylor (Severna Park, Maryland);  Amanda Canezin (Newton, Massachusetts);  Mariah Schrum (Jefferson Hills, Pennsylvania);  Iulian Iordachita (Lutherville, Maryland);  Gregory Chirikjian (Towson, Maryland);  Michelle Laskowski (Frederick, Maryland);  Sumana Chakravarty (Derwood, Maryland);  Stephen Hoffman (Gaithersburg, Maryland)
ABSTRACT A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.
FILED Tuesday, June 13, 2017
APPL NO 15/621875
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 47/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/10 (20130101)
C12N 3/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781425 Wells et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) James M. Wells (Cincinnati, Ohio);  Aaron M. Zorn (Cincinnati, Ohio);  Jason R. Spence (Ann Arbor, Michigan);  Noah F. Shroyer (Houston, Texas)
ABSTRACT The generation of complex organ tissues from human embryonic and pluripotent stem cells (PSCs) remains a major challenge for translational studies. It is shown that PSCs can be directed to differentiate into intestinal tissue in vitro by modulating the combinatorial activities of several signaling pathways in a step-wise fashion, effectively recapitulating in vivo fetal intestinal development. The resulting intestinal “organoids” were three-dimensional structures consisting of a polarized, columnar epithelium surrounded by mesenchyme that included a smooth muscle-like layer. The epithelium was patterned into crypt-like SOX9-positive proliferative zones and villus-like structures with all of the major functional cell types of the intestine. The culture system is used to demonstrate that expression of NEUROG3, a pro-endocrine transcription factor mutated in enteric anendocrinosis is sufficient to promote differentiation towards the enteroendocrine cell lineage. In conclusion, PSC-derived human intestinal tissue should allow for unprecedented studies of human intestinal development, homeostasis and disease.
FILED Tuesday, June 20, 2017
APPL NO 15/627588
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0661 (20130101)
C12N 5/0679 (20130101) Original (OR) Class
C12N 2501/16 (20130101)
C12N 2501/119 (20130101)
C12N 2501/155 (20130101)
C12N 2501/385 (20130101)
C12N 2501/415 (20130101)
C12N 2502/02 (20130101)
C12N 2502/45 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781427 Barouch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
NIH Office of the Director (NIHOD)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts);  Washington University (St. Louis, Missouri)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts);  Washington University (St. Louis, Missouri)
INVENTOR(S) Dan H. Barouch (Newton, Massachusetts);  Herbert Virgin, IV (St. Louis, Missouri);  Peter Abbink (Winthrop, Massachusetts)
ABSTRACT The present invention relates to recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are novel simian adenoviruses having a low seroprevalence and high immunogenicity relative to other adenoviruses and vectors thereof. The invention also provides methods for production of the adenoviruses and for the treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).
FILED Friday, October 12, 2018
APPL NO 16/159336
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 2039/5256 (20130101)
A61K 2039/5258 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2710/10042 (20130101)
C12N 2710/10321 (20130101)
C12N 2710/10343 (20130101)
C12N 2740/15034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781430 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Lili Wang (Phoenixville, Pennsylvania);  James M. Wilson (Philadelphia, Pennsylvania)
ABSTRACT Viral vectors comprising engineered hOTC DNA and RNA sequences are provided which when delivered to a subject in need thereof are useful for treating hyperammonemia, ornithine transcarbamylase transcarbamylasc deficiency and symptoms associated therewith. Also provided are methods of using hOTC for treatment of liver fibrosis and/or cirrhosis in OTCD patients by administering hOTC.
FILED Thursday, November 15, 2018
APPL NO 16/191709
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1018 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2710/10343 (20130101)
C12N 2740/15043 (20130101)
C12N 2750/14032 (20130101)
C12N 2750/14033 (20130101)
C12N 2750/14043 (20130101)
C12N 2750/14071 (20130101)
C12N 2750/14143 (20130101)
C12N 2800/22 (20130101)

Enzymes
C12Y 201/03003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781431 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) MARSHALL UNIVERSITY RESEARCH CORPORTION (Huntington, West Virginia)
ASSIGNEE(S) MARSHALL UNIVERSITY RESEARCH CORPORATION (Huntington, West Virginia)
INVENTOR(S) Zijian Xie (Huntington, West Virginia);  Moumita Banerjee (Huntington, West Virginia)
ABSTRACT Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.
FILED Thursday, April 02, 2015
APPL NO 15/129534
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/46 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/50 (20130101)
C12Q 1/485 (20130101)

Enzymes
C12Y 306/03009 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101)
G01N 33/5044 (20130101)
G01N 2333/91 (20130101)
G01N 2333/3153 (20130101)
G01N 2333/3156 (20130101)
G01N 2333/9723 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781444 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Ophir Shalem (Albany, California);  Neville Espi Sanjana (Cambridge, Massachusetts);  John Doench (Boston, Massachusetts);  David Root (Brookline, Massachusetts);  Ella Nicole Biewener Hartenian (Brookline, Massachusetts)
ABSTRACT The present invention generally relates to libraries, compositions, methods, applications, kits and screens used in functional genomics that focus on gene function in a cell and that may use vector systems and other aspects related to Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas systems and components thereof. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system.
FILED Thursday, December 17, 2015
APPL NO 14/973062
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/102 (20130101)
C12N 15/907 (20130101)
C12N 15/1082 (20130101)
C12N 15/1093 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781446 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky);  Daxiang Cui (Shanghai, China PRC);  Chunlei Zhang (Shanghai, China PRC)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Peixuan Guo (Columbus, Ohio);  Daxiang Cui (Shanghai, China PRC);  Dan Shu (Columbus, Ohio);  Yi Shu (Lexington, Kentucky);  Chunlei Zhang (Shanghai, China PRC)
ABSTRACT The presently-disclosed subject matter relates to RNA-based composition and method to treat gastric cancer in a subject. More particularly, the presently disclosed subject matter relates to a RNA nanostructure and composition containing a multiple branched RNA nanoparticle, a gastric cancer targeting module, and an effective amount of a therapeutic agent. Further, the presently disclosed subject matter relates to a method of using the RNA nanoparticle composition to treat gastric cancer in a subject having or at risk of having gastric cancer.
FILED Wednesday, March 09, 2016
APPL NO 15/556946
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 15/115 (20130101)
C12N 2310/14 (20130101)
C12N 2310/16 (20130101)
C12N 2310/52 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781451 Wilton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The University of Western Australia (Crawley, Australia)
ASSIGNEE(S) The University of Western Australia (Crawley, Australia)
INVENTOR(S) Stephen Donald Wilton (Applecross, Australia);  Sue Fletcher (Bayswater, Australia);  Graham McClorey (Bayswater, Australia)
ABSTRACT An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.
FILED Monday, July 01, 2019
APPL NO 16/458929
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/33 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/3233 (20130101)
C12N 2310/3341 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/30 (20130101)
C12N 2320/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781459 Byrne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Barry John Byrne (Gainesville, Florida);  Phillip A. Doerfler (Cordova, Tennessee);  Nathalie Clement (Gainesville, Florida)
ABSTRACT Provided herein are methods related to co-packaging of multiple rAAV particles, e.g., by introducing multiple nucleic acid vectors encoding proteins or polypeptides or RNAs of interest into a single cell preparation.
FILED Saturday, June 20, 2015
APPL NO 15/320707
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14143 (20130101)
C12N 2750/14152 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781477 Trautman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ARATOME, LLC (Menlo Park, California)
ASSIGNEE(S) ARATOME, LLC (Menlo Park, California)
INVENTOR(S) Jay Trautman (Los Altos, California);  Gordon Wang (San Jose, California);  David Lenzi (Menlo Park, California)
ABSTRACT Disclosed herein are compositions, kits, methods, and systems for detecting a target molecule in a sample using a detection molecule.
FILED Wednesday, January 23, 2019
APPL NO 16/254926
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 16/20 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/44 (20130101)
C12Q 1/68 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6818 (20130101)
C12Q 1/6823 (20130101)
C12Q 1/6827 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 1/6888 (20130101)
C12Q 2521/501 (20130101)
C12Q 2537/119 (20130101)
C12Q 2563/107 (20130101)

Enzymes
C12Y 605/01001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/36 (20130101)
G01N 33/532 (20130101)
G01N 33/533 (20130101)
G01N 33/582 (20130101)
G01N 33/585 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781487 Sheinerman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) DiamiR, LLC (Princeton, New Jersey)
ASSIGNEE(S) DIAMIR, LLC (Princeton, New Jersey)
INVENTOR(S) Kira S. Sheinerman (New York, New York);  Vladimir G. Tsivinsky (Sharon, Massachusetts);  Samuil R. Umansky (Princeton, New Jersey)
ABSTRACT The present invention is directed to methods for detection, treatment monitoring, and slowing of aging by quantifying miRNAs in bodily fluids.
FILED Tuesday, July 24, 2018
APPL NO 16/044279
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 1/6883 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781489 Samavati et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan);  HENRY FORD HEALTH SYSTEM (Detroit, Michigan)
ASSIGNEE(S) WAYNE STATE UNIVERSITY (Detroit, Michigan);  HENRY FORD HEALTH SYSTEM (Detroit, Michigan)
INVENTOR(S) Lobelia Samavati (Beverly Hills, Michigan);  Harvinder S. Talwar (Ypsilanti, Michigan);  Rita Rosati (Troy, Michigan);  Felix Fernandez-Madrid (Royal Oak, Michigan);  Jia Li (Northville, Michigan)
ABSTRACT Systems and methods to diagnose sarcoidosis are described. In addition to diagnosing sarcoidosis, the systems and methods can distinguish sarcoidosis from tuberculosis. Further disclosed is a cDNA library and methods of its use for reliably identifying sarcoidosis markers.
FILED Friday, March 04, 2016
APPL NO 15/555419
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5695 (20130101)
G01N 33/6893 (20130101)
G01N 2800/7095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781495 Linnen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) GEN-PROBE INCORPORATED (San Diego, California)
ASSIGNEE(S) GEN-PROBE INCORPORATED (San Diego, California)
INVENTOR(S) Jeffrey M. Linnen (Poway, California);  Reinhold B. Pollner (San Diego, California)
ABSTRACT Compositions for detecting flavivirus nucleic acids. Particularly described are compositions for detecting West Nile virus nucleic acids in the 3′ non-coding region. These compositions are preferably oligonucleotides comprising nucleotide sequences that are substantially complementary to a West Nile virus target nucleic acid. These compositions preferably comprise a detectable moiety.
FILED Friday, January 20, 2017
APPL NO 15/411448
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 1/6818 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782295 Cravatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Benjamin Cravatt (La Jolla, California);  Chu Wang (Beijing, China PRC);  Keriann Backus (San Diego, California)
ABSTRACT Cells produce electrophilic products with the potential to modify and affect the function of proteins. Chemoproteomic methods have provided a means to qualitatively inventory proteins targeted by endogenous electrophiles; however, ascertaining the potency and specificity of these reactions to identify the most sensitive sites in the proteome to electrophilic modification requires more quantitative methods. Here, we describe a competitive activity-based profiling method for quantifying the reactivity of electrophilic compounds against 1000+ cysteines in parallel in the human proteome. Using this approach, we identify a select set of proteins that constitute hot spots for modification by various lipid-derived electrophiles, including the oxidative stress product 4-hydroxnonenal (HNE). We show that one of these proteins, ZAK kinase, is labeled by HNE on a conserved, active site-proximal cysteine, resulting in enzyme inhibition to create a negative feedback mechanism that can suppress the activation of JNK pathways by oxidative stress.
FILED Wednesday, August 13, 2014
APPL NO 14/911316
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)

Enzymes
C12Y 207/11025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/573 (20130101) Original (OR) Class
G01N 33/6842 (20130101)
G01N 2333/91205 (20130101)
G01N 2500/04 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782297 Du et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Hong Du (Carmel, Indiana);  Cong Yan (Carmel, Indiana)
ABSTRACT The present invention provides diagnostics for identifying and distinguishing various types of lung cancers using serum and/or bronchioalveolar lavage fluid. Signatures of secretory proteins are used to identify and distinguish lung cancers. The biomarker signatures may also be used to separate lung cancers from other inflammatory diseases, monitor progression, or assess treatment efficacy.
FILED Wednesday, April 16, 2014
APPL NO 14/785067
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57423 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782302 Tainsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Michael Tainsky (Southfield, Michigan);  Madhumita Chatterjee (Lake Orion, Michigan);  Gregory Dyson (Northville, Michigan);  Nancy Levin (Birmingham, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Michael Tainsky (Southfield, Michigan);  Madhumita Chatterjee (Lake Orion, Michigan);  Gregory Dyson (Northville, Michigan);  Nancy Levin (Birmingham, Michigan)
ABSTRACT Polypeptide marker antigens for detecting the presence of autoantibody biomarkers associated with ovarian cancer recurrence, each of the polypeptide marker antigens binding specifically to at least one autoantibody marker. An antibody binding assay for detecting the presence of autoantibody biomarkers associated with ovarian cancer recurrence, and methods for performing the assay. Methods for determining ovarian cancer recurrence in an ovarian cancer patient. A method for isolating antibodies specific for ovarian cancer by their affinity to the polypeptide marker antigens, and antibodies isolated by that method.
FILED Tuesday, October 17, 2017
APPL NO 15/785898
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/00 (20130101)

Peptides
C07K 14/4748 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57449 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782308 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services, Centers For Disease Control and Prevention (Atlanta, Georgia)
ASSIGNEE(S) THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (Atlanta, Georgia)
INVENTOR(S) Jerome Smith (Cincinnati, Ohio);  Deborah Sammons (Cincinnati, Ohio);  Shirley Robertson (Cincinnati, Ohio)
ABSTRACT Methods, kits and devices for detecting antineoplastic drug contamination of a surface are provided according to aspects of the present invention. According to aspects of the invention, methods for detecting antineoplastic drug contamination of a surface include providing a wetting solution compatible with the antineoplastic drug and formulated to promote release of the drug from the surface to be assayed; providing a solid matrix for reversible absorption of the antineoplastic drug; contacting the solid matrix with the wetting solution, generating an assay matrix; contacting the assay matrix and the surface, generating a surface sample; contacting the surface sample with a volume of wetting solution, generating a fluid test sample; and quantifying the antineoplastic drug in the fluid test sample by lateral flow assay to produce an assay result, thereby detecting antineoplastic drug contamination of the surface.
FILED Tuesday, July 16, 2013
APPL NO 13/943430
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/94 (20130101) Original (OR) Class
G01N 33/558 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782373 Altbach et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Maria Altbach (Tucson, Arizona);  Ali Bilgin (Tucson, Arizona);  Chuan Huang (Stony Brook, New York);  Christian Graff (Tucson, Arizona)
ABSTRACT A system and method for processing highly undersampled multi-echo spin-echo data by linearizing the slice-resolved extended phase graph model generates highly accurate T2 maps with indirect echo compensation. Principal components are used to linearize the signal model to estimate the T2 decay curves which can be fitted to the slice-resolved model for T2 estimation. In another example of image processing for highly undersampled data, a joint bi-exponential fitting process can compensate for image variations within a voxel and thus provide partial voxel compensation to produce more accurate T2 maps.
FILED Friday, August 02, 2019
APPL NO 16/530905
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/4244 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/54 (20130101) Original (OR) Class
G01R 33/4818 (20130101)
G01R 33/5611 (20130101)
G01R 33/5617 (20130101)

Electric Digital Data Processing
G06F 19/321 (20130101)

Image Data Processing or Generation, in General
G06T 2211/436 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782375 Tamir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jonathan I. Tamir (Berkeley, California);  Shimon Michael Lustig (Moraga, California)
ABSTRACT In a volumetric fast spin-echo magnetic resonance imaging system a plurality of radio frequency pulses can be emitted. The plurality of radio frequency pulses can be directed toward a target sample. The plurality of radio frequency pulses can have a set of repetition times. The set of repetition times can define a frequency at which the plurality of radio frequency pulses are emitted. The set of repetition times can be varied during the emitting of the plurality of the radio frequency pulses. Magnetic resonance imaging data of a target sample can be received. A pseudo-random sampling pattern can be used to facilitate the receiving of the magnetic resonance imaging data having multiple magnetic resonance imaging contrasts for a single scan.
FILED Friday, April 07, 2017
APPL NO 15/482658
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/4822 (20130101)
G01R 33/5602 (20130101) Original (OR) Class
G01R 33/5617 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782376 Warfield et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Mental Health (NIMH)
National Library of Medicine (NLM)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Simon K. Warfield (Brookline, Massachusetts);  Benoit Scherrer (Cambridge, Massachusetts)
ABSTRACT Methods and apparatus for acquiring diffusion-weighted images. The method comprises selecting a plurality of diffusion gradient vectors, wherein at least two of the plurality of diffusion gradient vectors correspond to different non-zero b-values. The method further comprises determining a gradient strength for each of the plurality of diffusion gradient vectors such that an echo image time (TE) remains constant when gradients corresponding to each of the plurality of diffusion gradient vectors are applied. The method further comprises acquiring the diffusion-weighted images using a gradient encoding scheme including the gradients corresponding to each of the plurality of gradient vectors.
FILED Friday, September 27, 2013
APPL NO 14/431536
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/385 (20130101)
G01R 33/5602 (20130101)
G01R 33/5608 (20130101)
G01R 33/56341 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782378 Bolster, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Siemens Healthcare GmbH (Erlangen, Germany);  University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Bradley Drake Bolster, Jr. (Rochester, Minnesota);  Ganesh Sharma Adluru Venkata Raja (Salt Lake City, Utah);  Edward DiBella (Salt Lake City, Utah)
ABSTRACT A method for reducing artifacts in magnetic resonance imaging (MRI) data includes acquiring a k-space dataset of an anatomical subject using a MRI scanner. An iterative compressed sensing reconstruction method is used to generate a reconstructed image based on the k-space dataset. This iterative compressed sensing reconstruction method uses (a) L1-norm based total variation constraints applied the temporal and spatial dimensions of the k-space dataset and (b) a low rank constraint. After the reconstructed image is generated, a deep learning network is used to generate an artifact image depicting motion artifacts present in the reconstructed image. The reconstructed image is subtracted from the artifact image to yield a final image with the motion artifacts removed.
FILED Wednesday, May 16, 2018
APPL NO 15/980774
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0402 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56509 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0051 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783627 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Cheng Lu (Cleveland Heights, Ohio)
ABSTRACT Embodiments include apparatus for predicting cancer recurrence based on local co-occurrence of cell morphology (LoCoM). The apparatus includes image acquisition circuitry that identifies and segments at least one cellular nucleus represented in an image of a region of tissue demonstrating cancerous pathology; local nuclei graph (LNG) circuitry that constructs an LNG based on the at least one cellular nucleus, and computes a set of nuclear morphology features for a nucleus represented in the LNG; LoCoM circuitry that constructs a co-occurrence matrix based on the nuclear morphology features, computes a set of LoCoM features for the co-occurrence matrix, and computes a LoCoM signature for the image based on the set of LoCoM features; progression circuitry that generates a probability that the region of tissue will experience cancer progression based on the LoCoM signature, and classifies the region of tissue as a progressor or non-progressor based on the probability.
FILED Monday, February 19, 2018
APPL NO 15/898728
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00147 (20130101)
G06K 2209/05 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/45 (20170101)
G06T 7/62 (20170101)
G06T 7/77 (20170101)
G06T 7/155 (20170101)
G06T 7/162 (20170101)
G06T 7/529 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/20072 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/30024 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/20 (20180101)
G16H 50/50 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783632 Fan et al.
FUNDED BY
Department of Defense (DOD)
Defense Health Agency (DHA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) SPECTRAL MD, INC. (Dallas, Texas)
ASSIGNEE(S) SPECTRAL MD, INC. (Dallas, Texas)
INVENTOR(S) Wensheng Fan (Plano, Texas);  John Michael DiMaio (Dallas, Texas);  Jeffrey E. Thatcher (Irving, Texas);  Peiran Quan (Dallas, Texas);  Faliu Yi (Allen, Texas);  Kevin Plant (Dallas, Texas);  Ronald Baxter (Grand Prairie, Texas);  Brian McCall (Dallas, Texas);  Zhicun Gao (Plano, Texas);  Jason Dwight (Dallas, Texas)
ABSTRACT Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.
FILED Thursday, January 09, 2020
APPL NO 16/738911
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/445 (20130101)
A61B 5/7275 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/20081 (20130101)
G06T 2207/30088 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10779635 Garrison et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Connor Garrison (Plano, Texas);  Julianne Douglas (Belcamp, Maryland)
ABSTRACT Various embodiments are described that relate to energy generation. A housing can retain a spring coupled to a gear set. As the spring experiences linear compression and extension, the spring can cause rotational movement in the gear set. The rotational movement from the gear set can cause rotation of a rotational magnet. The rotational magnet, when rotated about a coil set, can convert an energy. The energy can be used to charge a battery.
FILED Monday, September 26, 2016
APPL NO 15/275543
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Purses; Luggage; Hand Carried Bags
A45C 15/00 (20130101)

Travelling or Camp Equipment: Sacks or Packs Carried on the Body
A45F 3/06 (20130101) Original (OR) Class
A45F 2003/003 (20130101)
A45F 2005/002 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/32 (20130101)

Dynamo-electric Machines
H02K 7/116 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779746 Even-Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Nir Even-Chen (Palo Alto, California);  Krishna V. Shenoy (Palo Alto, California);  Jonathan C. Kao (Los Angeles, California);  Sergey Stavisky (San Francisco, California)
ABSTRACT A brain machine interface (BMI) for improving a performance of a subject is provided. The BMI has two decoders that act in real-time and in parallel to each other. The first decoder is for intention execution of a subject's intention. The second decoder is for error detection in a closed-loop error fashion with the first detector and to improve the performance of the first detector. Embodiments of this invention may enable an entirely new way to substantially increase the performance and robustness, user experience, and ultimately the clinical viability of BMI systems.
FILED Thursday, August 11, 2016
APPL NO 15/234844
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0482 (20130101) Original (OR) Class
A61B 5/04012 (20130101)
A61B 5/7267 (20130101)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
G06N 20/20 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779757 Berthier et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Tasso, Inc. (Madison, Wisconsin)
ASSIGNEE(S) Tasso, Inc. (Seattle, Washington)
INVENTOR(S) Erwin Berthier (Madison, Wisconsin);  Ben Casavant (Seattle, Washington);  Ben Moga (Houston, Texas)
ABSTRACT The disclosed apparatus, systems and methods relate to the collection of bodily fluids through the use of gravity and microfluidic properties by way of a collector. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a reservoir by a combination of capillary action and gravitational forces. The collected fluid is moved through the microfluidic networks and into the reservoir by a variety of approaches.
FILED Monday, August 03, 2015
APPL NO 14/816994
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/15113 (20130101)
A61B 5/15142 (20130101)
A61B 5/150022 (20130101)
A61B 5/150099 (20130101)
A61B 5/150251 (20130101)
A61B 5/150343 (20130101)
A61B 5/150358 (20130101) Original (OR) Class
A61B 5/150412 (20130101)
A61B 5/150503 (20130101)
A61B 5/150977 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0457 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10779963 Chestek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Cynthia Anne Chestek (Ann Arbor, Michigan);  Melanie G. Urbanchek (Fullerton, California);  Paul S. Cederna (Grass Lake, Michigan);  Richard Brent Gillespie (Ann Arbor, Michigan);  Nicholas B. Langhals (Haslett, Michigan);  Zachary Irwin (Ann Arbor, Michigan);  Daniel C. Ursu (Ann Arbor, Michigan)
ABSTRACT The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.
FILED Monday, May 06, 2019
APPL NO 16/404343
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101) Original (OR) Class
A61F 2/583 (20130101)
A61F 2002/701 (20130101)
A61F 2002/704 (20130101)
A61F 2002/5058 (20130101)
A61F 2002/5064 (20130101)
A61F 2002/6827 (20130101)
A61F 2002/6872 (20130101)
A61F 2002/7635 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780185 Delehanty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James B. Delehanty (Washington, District of Columbia);  Michael H. Stewart (Springfield, Virginia);  Okhil Nag (Alexandria, Virginia);  Jeffrey R. Deschamps (Laurel, Maryland);  Kimihiro Susumu (Alexandria, Virginia);  Eunkeu Oh (Alexandria, Virginia);  Lauren D. Field (College Park, Maryland);  Alexander L. Efros (Annandale, Virginia);  Alan L. Huston (Aldie, Virginia);  Igor L. Medintz (Springfield, Virginia);  Philip E. Dawson (San Diego, California);  Nashaat Rasheed (Fairfax, Virginia);  Parag V. Chitnis (Fairfax, Virginia);  John R. Cressman (Fairfax, Virginia)
ABSTRACT A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Photoacoustic emission from the construct correlates with cellular membrane potential.
FILED Tuesday, July 10, 2018
APPL NO 16/031094
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/221 (20130101)
A61K 49/222 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/542 (20130101)
G01N 33/588 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780410 Jensen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Klavs F. Jensen (Lexington, Massachusetts);  Timothy F. Jamison (Cambridge, Massachusetts);  Allan S. Myerson (Boston, Massachusetts);  Jean-Christophe M. Monbaliu (Esneux, Belgium);  Mohsen Behnam (Worcester, Massachusetts);  Shin Yee Wong (Singapore, Singapore);  Nopphon Weeranoppanant (Muang, Thailand);  Eve Marie Revalor (Rognes, France);  Torsten Stelzer (Caguas, Puerto Rico);  Jie Chen (Evanston, Illinois);  Andrea Adamo (Cambridge, Massachusetts);  David R. Snead (Atlanta, Georgia);  Ping Zhang (Somerville, Massachusetts)
ABSTRACT Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
FILED Friday, August 14, 2015
APPL NO 15/504049
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/14 (20130101)
A61K 31/167 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/004 (20130101) Original (OR) Class
B01J 19/18 (20130101)
B01J 19/0093 (20130101)
B01J 2219/0002 (20130101)
B01J 2219/0004 (20130101)
B01J 2219/00011 (20130101)
B01J 2219/0081 (20130101)
B01J 2219/00795 (20130101)
B01J 2219/00799 (20130101)
B01J 2219/00806 (20130101)
B01J 2219/00813 (20130101)
B01J 2219/00817 (20130101)
B01J 2219/00822 (20130101)
B01J 2219/00831 (20130101)
B01J 2219/00833 (20130101)
B01J 2219/00835 (20130101)
B01J 2219/00871 (20130101)
B01J 2219/00873 (20130101)
B01J 2219/00889 (20130101)
B01J 2219/00907 (20130101)
B01J 2219/00909 (20130101)
B01J 2219/00918 (20130101)
B01J 2219/00986 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780588 Smith et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
APPLICANT(S) Sarcos LC (Salt Lake City, Utah)
ASSIGNEE(S) Sarcos LC (Salt Lake City, Utah)
INVENTOR(S) Fraser M. Smith (Salt Lake City, Utah);  Michael Morrison (West Jordan, Utah);  Glenn Colvin, Jr. (Park City, Utah);  Wayco Scroggin (Sandy, Utah)
ABSTRACT An end effector for a robotic arm is disclosed. The end effector includes a grasping apparatus having a gripping member and an appendage extending from the gripping member forming a channel between the griping member and the appendage. The channel is configured to receive at least a portion of an article, such as a latch for a container, to be manipulated by the end effector.
FILED Tuesday, April 11, 2017
APPL NO 15/484929
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 15/10 (20130101)
B25J 15/0066 (20130101) Original (OR) Class
B25J 15/0475 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/39 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781099 Becker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Carol A. Becker (Del Mar, California);  Wayne E. Glad (Del Mar, California);  Brandon J. Wiedemeier (San Diego, California)
ABSTRACT An underwater hydrogen generator can include a watertight reaction housing enclosing a metering chamber. The metering chamber can have an upper portion that terminates at a piston opening, and a lower portion that merges into a funnel, which can further terminate at a metering opening. The metering chamber can be filled with an acid accelerator, and the watertight reaction void can be partially filled with NaBH4 in solution. The generator can further include a seawater float valve that can be in fluid communication between the external environment, the metering chamber and the void defined by the reaction housing. The float valve, metering chamber and reaction housing can cooperate to generate hydrogen when said generator is submerged, by allowing seawater to contact both the acid accelerator and the NaBH4. The size of the metering opening can determine the rate at which acid accelerator is added to the NaBH4 solution.
FILED Wednesday, June 27, 2018
APPL NO 16/019645
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0006 (20130101)
B01J 2219/00182 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/06 (20130101) Original (OR) Class
C01B 3/061 (20130101)
C01B 3/065 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/065 (20130101)
H01M 8/04201 (20130101)
H01M 8/04208 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781419 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Aberdeen Proving Ground (APG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanaria Inc. (Rockville, Maryland);  Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Sanaria Inc. (Rockville, Maryland);  Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Russell H. Taylor (Severna Park, Maryland);  Amanda Canezin (Newton, Massachusetts);  Mariah Schrum (Jefferson Hills, Pennsylvania);  Iulian Iordachita (Lutherville, Maryland);  Gregory Chirikjian (Towson, Maryland);  Michelle Laskowski (Frederick, Maryland);  Sumana Chakravarty (Derwood, Maryland);  Stephen Hoffman (Gaithersburg, Maryland)
ABSTRACT A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.
FILED Tuesday, June 13, 2017
APPL NO 15/621875
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 47/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/10 (20130101)
C12N 3/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781716 Tholen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Susan M. Tholen (Kennebunk, Maine);  Dominic J. Mongillo (West Hartford, Connecticut);  Paul M. Lutjen (Kennebunkport, Maine);  James N. Knapp (Sanford, Maine);  Virginia L. Ross (Madison, Wisconsin);  Jonathan J. Earl (Wells, Maine);  Eric A. Hudson (Harwinton, Connecticut)
ABSTRACT A cooling scheme for a blade outer air seal includes a perimeter cooling arrangement configured to convectively cool a perimeter of the blade outer air seal, and a core cooling arrangement configured to cool a central portion of the blade outer air seal through impingement cooling and to provide film cooling to an inner diameter face of the blade outer air seal.
FILED Monday, January 21, 2019
APPL NO 16/253038
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Foundry Moulding
B22C 9/103 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/08 (20130101)
F01D 25/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781751 Jones et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Russell B Jones (North Palm Beach, Florida);  Cheryl A Schopf (Jupiter, Florida)
ABSTRACT A gas turbine engine for an aircraft such as a UAV includes a compressor connected to a turbine with a combustor to produce a hot gas stream. The rotor is supported by two radial foil bearings. An axial thrust bearing assembly is positioned between the compressor disk and the turbine disk and includes an axial thrust bearing radial disk extending from a hollow axial tube. Compressed air is bled off from the compressor and passed into an axial thrust balance chamber to provide the axial thrust balance for the rotor. The compressed air from the thrust bearing chamber then flows through both of the radial foil bearings for cooling, is collected in and around the hollow tube, and then discharged into the inlet of the turbine. An orifice can be adjusted to meter and control a pressure occurring in the thrust balance chamber.
FILED Thursday, March 22, 2018
APPL NO 15/928500
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)
B64C 2201/048 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/10 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/085 (20130101)
F02C 7/06 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2240/52 (20130101)
F05D 2240/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782071 Cerny et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Contract Management Agency (DCMA)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Matthew Robert Cerny (West Chester, Ohio);  Nicholas Allan Wilson (Cincinnati, Ohio);  Nicholas Taylor Moore (Cincinnati, Ohio)
ABSTRACT A tubular array heat exchanger and a method of manufacturing the same are provided. The heat exchanger includes a plurality of tubes extending between a tube inlet and a tube outlet. An inlet manifold includes an inner wall and an outer wall defining an inlet plenum and one or more baffles extending between the inner wall and the outer wall to divide the inlet plenum into a plurality of fluid passageways, each of the plurality of fluid passageways extending between the inlet plenum and a respective one of the tube inlets. The tubes, the inlet manifold, and an outlet manifold identical to the inlet manifold are manufactured as a single monolithic component.
FILED Tuesday, March 28, 2017
APPL NO 15/471356
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/26 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 80/00 (20141201)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 1/0472 (20130101) Original (OR) Class
F28D 7/024 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 9/02 (20130101)
F28F 9/0268 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782107 Dindl
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Frank Dindl (Newton, New Jersey)
ABSTRACT The rifle system comprises a rifle and an ammunition round for operation with the rifle. The high pressure ammunition round further comprises a cartridge case having an outer wall wherein prior to firing of the ammunition round, the outer wall geometry of the cartridge case is devoid of features configured for interfacing with a mechanical extractor. The rifle further comprising a barrel chamber which fully supports a chambered cartridge case and a rear extraction mechanism for extracting a spent cartridge case through the rear of the barrel chamber.
FILED Tuesday, October 29, 2019
APPL NO 16/666817
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 15/00 (20130101)
F41A 15/04 (20130101)
F41A 15/12 (20130101)
F41A 21/28 (20130101)

Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 11/62 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 5/02 (20130101)
F42B 5/26 (20130101)
F42B 5/28 (20130101) Original (OR) Class
F42B 5/30 (20130101)
F42B 39/087 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/083 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782134 Biren et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Marvin A. Biren (Chestnut Hill, Massachusetts);  Simone B. Bortolami (Belmont, Massachusetts);  Benjamin J. Bresler (Cambridge, Massachusetts)
ABSTRACT Methods for use in celestial navigation system use multiple star observations from an unknown observer location using an observer camera with an observational field of view along a boresight axis and a focal plane perpendicular to the boresight axis. An observer local ECI coordinate system is determined from the star observations. Then for each of multiple observable objects in orbit around the Earth, multiple optical angular measurements relative to stars are performed over time to estimate its orbital ellipse, and its focus at the center of the Earth. From the multiple focus estimates, a position of the center of the Earth is estimated in the observer local coordinate system without use of object ephemeris data. From the estimated position of the center of the Earth, a radius vector to the observer is determined that represents the estimated observer location in Earth centered Earth fixed coordinates.
FILED Tuesday, July 17, 2018
APPL NO 16/037094
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782181 Cochran
FUNDED BY
Department of Defense (DOD)
Defense Medical Research and Development Program (DMRDP)
Department of the Navy (DON)
APPLICANT(S) Grant Cochran (La Mesa, Maryland)
ASSIGNEE(S) The United States of America as Represented by the secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Grant Cochran (La Mesa, Maryland)
ABSTRACT A radiograph stand allowing weight placed on an injured leg/foot be measured and recorded while taking a weight-bearing radiograph. A method for taking weight bearing radiograph of a patient's foot, ankle, leg, knee, thigh, hip, pelvis, and spine.
FILED Thursday, April 05, 2018
APPL NO 15/946339
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/04 (20130101)
A61B 6/4283 (20130101)

Weighing
G01G 19/50 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782287 Mrksich et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Milan Mrksich (Hinsdale, Illinois);  Patrick O'Kane (Chicago, Illinois)
ABSTRACT Disclosed herein are methods of using an immobilized substrate, immobilized ligand, and a fusion protein of an enzyme for the substrate and a receptor for the ligand, where the immobilized substrate can react to form an immobilized product that has a different mass than the immobilized substrate, and using this transformation to indirectly determine the binding of the receptor and the ligand. These methods can be used for high-throughput screening for possible modulators (e.g., inhibitors or activators) of the ligand-receptor interaction.
FILED Tuesday, February 23, 2016
APPL NO 15/051338
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/54353 (20130101)
G01N 2333/47 (20130101)
G01N 2333/98 (20130101)
G01N 2560/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782289 Ozdemir et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Sahin Kaya Ozdemir (St. Louis, Missouri);  Lan Yang (St. Louis, Missouri)
ABSTRACT A micro-resonator and fiber taper based sensing system, which uses mode splitting or frequency shift methods and polarization measurements for particle sensing.
FILED Thursday, November 02, 2017
APPL NO 15/801823
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1429 (20130101)
G01N 15/1434 (20130101)
G01N 15/1463 (20130101)
G01N 21/21 (20130101)
G01N 21/45 (20130101)
G01N 21/7746 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2015/0038 (20130101)
G01N 2015/1454 (20130101)
G01N 2021/458 (20130101)
G01N 2201/08 (20130101)
G01N 2201/0683 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782401 Blanche
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Pierre Alexandre Blanche (Tucson, Arizona)
ABSTRACT Optical modality configured to simulate measurements of the radar cross-section of targets, dimensioned to be conventionally-measured in the RF-portion of the electromagnetic spectrum, with sub-micron accuracy. A corresponding compact optical system, with a foot-print comparable with a tabletop, employing optical interferometric time-of-flight approach to reproduce, on a substantially shorter time-scale, radar-ranging measurements ordinarily pertaining to the range of frequencies that are at least 103 times lower than those employed in the conventional RF-based measurement.
FILED Monday, May 07, 2018
APPL NO 15/973125
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/41 (20130101)
G01S 7/4865 (20130101)
G01S 13/865 (20130101) Original (OR) Class
G01S 13/9011 (20130101)
G01S 13/9023 (20130101)
G01S 17/006 (20130101)
G01S 17/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782509 Oskotsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Mark L Oskotsky (Mamaroneck, New York);  Michael J Russo, Jr. (Roslyn, New York);  Daniel Engheben (Commack, New York);  Erik L Hugel (Garden City, New York);  Shawn C Reven (Greenlawn, New York);  Vincent Lipari (Whitestone, New York);  Jerry Ma (Flushing, New York);  Yueli Zhang (Saint James, New York)
ABSTRACT An orthoscopic, apochromatic lens is suitable for deployment such as on aerial platforms provides distortion less than 0.2% over a full field of view of more than 60° with F # less than 6.5 and focal length greater than 3″, and in embodiments greater than 5″. Embodiments are apochromatic from 500 to 950 nm to within 7 microns. Embodiments have an overall length of less than 7″. The lens includes five optical groups with an aperture stop between the second and third groups. The optical groups have one, one, two, one and one optical element each, as ordered from the object to the image plane, and have positive, negative, positive, positive, and negative optical powers, respectively. Embodiments are telephoto. In embodiments the focal length is temperature invariant within 0.0015 inches from 0° C. to 40° C.
FILED Friday, September 14, 2018
APPL NO 16/131845
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 9/62 (20130101)
G02B 13/02 (20130101) Original (OR) Class
G02B 13/006 (20130101)
G02B 13/18 (20130101)
G02B 13/0045 (20130101)
G02B 27/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782726 Amir et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Arnon Amir (Saratoga, California);  Pallab Datta (San Jose, California);  Nimrod Megiddo (Palo Alto, California);  Dharmendra S. Modha (San Jose, California)
ABSTRACT In one embodiment, a computer program product for optimizing core utilization in a neurosynaptic network includes a computer readable storage medium having program instructions embodied therewith, where the computer readable storage medium is not a transitory signal per se, and where the program instructions are executable by a processor to cause the processor to perform a method including identifying, by the processor, one or more unused portions of a neurosynaptic network, and for each of the one or more unused portions of the neurosynaptic network, disconnecting, by the processor, the unused portion from the neurosynaptic network.
FILED Tuesday, April 02, 2019
APPL NO 16/373519
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Optical Computing Devices;
G06E 1/00 (20130101) Original (OR) Class
G06E 3/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/049 (20130101)
G06N 3/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782936 Davis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota)
INVENTOR(S) Paul Davis (Saratoga, California);  Doug Sweet (Sunnyvale, California);  Mark Peters (Newport News, Virginia)
ABSTRACT A computer-implemented method for migrating a monolithic legacy software system to a well-defined modular target software architecture includes selecting a method, based on predefined patterns, for transforming the software legacy software system; creating an abstract syntax tree from the legacy software system's source code; from the abstract syntax tree, determining a flow of the source code and any coding violations and coding smells in the legacy software system's source code; using the flow and the coding violations, identifying architecture issues in the legacy software system; scheduling tasks for transforming the legacy software system into the target software architecture; automatically generating new source code according to the target software architecture; and automatically and autonomously refactoring the new source code.
FILED Wednesday, January 30, 2019
APPL NO 16/262409
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/30 (20130101) Original (OR) Class
G06F 8/72 (20130101)
G06F 8/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783140 Ackermann et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Chris F. Ackermann (Fairfax, Virginia);  Charles E. Beller (Baltimore, Maryland);  Stephen A. Boxwell (Columbus, Ohio);  Stanley J. Vernier (Grove City, Ohio)
ABSTRACT A method comprising receiving, by a question and answer system, a first question, generating, by the question and answer system, a first answer set corresponding to the first question, each answer in the first answer set including one or more evidence passages, identifying, by the question and answer system, a geospatial or temporal modifier in the evidence passages, generating, by the question and answer system, a second question based on the first question and the geospatial or temporal modifier, generating, by the question and answer system, a second answer set corresponding to the second question, and returning, by the question and answer system, a question answer set based on the second answer set to a user.
FILED Monday, June 19, 2017
APPL NO 15/627179
ART UNIT 2153 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/2465 (20190101)
G06F 16/2477 (20190101)
G06F 16/3325 (20190101)
G06F 16/9537 (20190101)
G06F 16/24522 (20190101) Original (OR) Class
G06F 16/24578 (20190101)
G06F 17/10 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/00 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 7/02 (20130101)

Wireless Communication Networks
H04W 4/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783254 Sharma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Praveen Kaushik Sharma (Ashland, Massachusetts);  Pierre C. Trepagnier (Medford, Massachusetts);  Evan J. Fiore (Chelmsford, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Praveen Kaushik Sharma (Ashland, Massachusetts);  Pierre C. Trepagnier (Medford, Massachusetts);  Evan J. Fiore (Chelmsford, Massachusetts)
ABSTRACT Systems, methods and computer readable medium for training a risk rating system for assessing a risk of a mobile application are disclosed. One or more features representing operational characteristics of mobile applications and malware are extracted. A first learning classifier and a second learning classifier are trained using the extracted features. A machine learning risk rating model is generated, based on the combination of the first learning classifier and the second learning classifier to calculate a risk rating based on the features and a correlation of the features. Systems, methods, and computer readable medium for assessing a risk for a mobile application are also disclosed. One or more features of a mobile application are extracted. A learning classifier is applied to the extracted features. A risk rating is determined based on the result of the classifier.
FILED Thursday, October 02, 2014
APPL NO 14/505273
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/56 (20130101)
G06F 21/577 (20130101) Original (OR) Class
G06F 2221/033 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783430 Wittenberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Boeing Company (Chicago, Illinois);  HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois);  HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Peter S. Wittenberg (Creve Coeur, Missouri);  Peter Petre (Oak Park, California);  Shankar R. Rao (Agoura Hills, California)
ABSTRACT A method for removing an extracted RF signal to examine a spectrum of at least one other RF signal includes receiving a mixture signal by an ADC. The mixture signal includes a plurality of separate signals from different signal sources. The mixture signal is digitized by the ADC. A first digitized signal and a second digitized signal are generated that are the same. The first digitized signal is delayed a predetermined time delay and the second digitized signal is processed in a neuromorphic signal processor to extract an extracted signal. The predetermined time delay corresponds to a delay embedding in the neuromorphic signal processor. A phase delay and amplitude of the extracted signal is adjusted based on a phase delay and amplitude of the first digitized signal. An adjusted extracted signal is cancelled from the first digitized signal to provide an input examination signal for examination.
FILED Monday, September 26, 2016
APPL NO 15/276188
ART UNIT 2122 — AI & Simulation/Modeling
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 23/167 (20130101)

Electric Digital Data Processing
G06F 17/16 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/06 (20130101)
G06N 3/084 (20130101)
G06N 3/0445 (20130101)
G06N 3/0635 (20130101) Original (OR) Class

Amplifiers
H03F 3/19 (20130101)
H03F 2200/451 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 17/0294 (20130101)
H03H 21/0012 (20130101)
H03H 2017/009 (20130101)
H03H 2017/0081 (20130101)

Transmission
H04B 1/0007 (20130101)
H04B 1/123 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783441 Riabov et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Anton V. Riabov (Ann Arbor, Michigan);  Shirin Sohrabi Araghi (White Plains, New York);  Octavian Udrea (Ossining, New York)
ABSTRACT In at least one embodiment, a method and a system for determining a set of plans that best match a set of preferences. The method may include receiving into a goal specification interface at least one goal to be accomplished by the set of plans; receiving into a preference engine a pattern that includes preferences; generating a planning problem by using the preference engine; generating a set of plans by at least one planner; and providing the set of plans for selection of one plan to deploy. In a further embodiment, the preferences may be an occurrence or non-occurrence of at least one component, an occurrence of one component over another component, an ordering between at least two components, an existence or non-existence of at least one tag in a final stream, an existence of one tag over another tag in the final stream.
FILED Tuesday, April 11, 2017
APPL NO 15/484727
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 7/523 (20130101)
G06F 16/22 (20190101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783627 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Cheng Lu (Cleveland Heights, Ohio)
ABSTRACT Embodiments include apparatus for predicting cancer recurrence based on local co-occurrence of cell morphology (LoCoM). The apparatus includes image acquisition circuitry that identifies and segments at least one cellular nucleus represented in an image of a region of tissue demonstrating cancerous pathology; local nuclei graph (LNG) circuitry that constructs an LNG based on the at least one cellular nucleus, and computes a set of nuclear morphology features for a nucleus represented in the LNG; LoCoM circuitry that constructs a co-occurrence matrix based on the nuclear morphology features, computes a set of LoCoM features for the co-occurrence matrix, and computes a LoCoM signature for the image based on the set of LoCoM features; progression circuitry that generates a probability that the region of tissue will experience cancer progression based on the LoCoM signature, and classifies the region of tissue as a progressor or non-progressor based on the probability.
FILED Monday, February 19, 2018
APPL NO 15/898728
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00147 (20130101)
G06K 2209/05 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/45 (20170101)
G06T 7/62 (20170101)
G06T 7/77 (20170101)
G06T 7/155 (20170101)
G06T 7/162 (20170101)
G06T 7/529 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/20072 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/30024 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/20 (20180101)
G16H 50/50 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783632 Fan et al.
FUNDED BY
Department of Defense (DOD)
Defense Health Agency (DHA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) SPECTRAL MD, INC. (Dallas, Texas)
ASSIGNEE(S) SPECTRAL MD, INC. (Dallas, Texas)
INVENTOR(S) Wensheng Fan (Plano, Texas);  John Michael DiMaio (Dallas, Texas);  Jeffrey E. Thatcher (Irving, Texas);  Peiran Quan (Dallas, Texas);  Faliu Yi (Allen, Texas);  Kevin Plant (Dallas, Texas);  Ronald Baxter (Grand Prairie, Texas);  Brian McCall (Dallas, Texas);  Zhicun Gao (Plano, Texas);  Jason Dwight (Dallas, Texas)
ABSTRACT Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.
FILED Thursday, January 09, 2020
APPL NO 16/738911
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/445 (20130101)
A61B 5/7275 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/20081 (20130101)
G06T 2207/30088 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783801 Beaubien et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Aptima, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Aptima, Inc. (Woburn, Massachusetts)
INVENTOR(S) Jeffrey Beaubien (Londonderry, New Hampshire);  John J. Feeney (Beavercreek, Ohio);  William N. DePriest (Dayton, Ohio);  Scott M. Pappada (Waterville, Ohio)
ABSTRACT In one example embodiment of the invention, a simulation based training system is provided having a sensor that unobtrusively collects objective data for individuals and teams experiencing training content to determine the cognitive states of individuals and teams; time-synchronizes the various data streams; automatically determines granular and objective measures for individual cognitive load (CL) of individuals and teams; and automatically determines a cognitive load balance (CLB) and a relative cognitive load (RCL) measure in real or near-real time. Data is unobtrusively gathered through physiological or other activity sensors such as electroencephalogram (EEG) and electrocardiogram (ECG) sensors. Some embodiments are further configured to also include sociometric data in the determining cognitive load. Sociometric data may be obtained through the use of sociometric badges. Some embodiments further automatically customize the simulation content by automatically selecting content based on the CL of the individuals and teams.
FILED Thursday, December 21, 2017
APPL NO 15/850998
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/16 (20130101)
A61B 5/0245 (20130101)
A61B 5/0476 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 7/10 (20130101)
G09B 9/00 (20130101) Original (OR) Class
G09B 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783871 Norris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Andrew N. Norris (Mountainside, New Jersey);  Xiaoshi Su (Manalapan, New Jersey)
ABSTRACT A metal acoustic lens comprises a plurality of stacked plates, wherein each plate comprises an acoustically transparent two-dimensional material structure comprising a plurality of adjacent regular hexagonal cells, wherein each hexagonal cell includes a plurality of lobes extending inwardly from the vertices of the hexagonal cell, and wherein the lengths of the lobes vary across each plate in the longitudinal direction such that the speed of sound waves passing therethrough is varied and the resulting sound is focused.
FILED Wednesday, October 04, 2017
APPL NO 15/724812
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784011 Cumby et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Brad L Cumby (Cincinnati, Ohio);  Christopher Tabor (Kettering, Ohio)
ABSTRACT A deformable yet mechanically resilient microcapsule having electrical properties, a method of making the microcapsules, and a circuit component including the microcapsules. The microcapsule containing a gallium liquid metal alloy core having from about 60 to about 100 wt. % gallium and at least one alloying metal, and a polymeric shell encapsulating the liquid core, said polymeric shell having conductive properties.
FILED Tuesday, May 22, 2018
APPL NO 15/986292
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Alloys
C22C 28/00 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101) Original (OR) Class
H01B 13/0036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784173 Heller
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Eric Heller (Kettering, Ohio)
ABSTRACT A method of evaluating localized degradation of a III-V compound semiconductor. The method includes preparing first and second III-V compound semiconductors. The second III-V compound semiconductor that is similar to the first III-V compound semiconductor and further comprises a shield layer that is configured to alter exposed portions of channels of the second III-V compound semiconductor. The first and second III-V compound semiconductors and irradiated and then electrically tested. Results of the electrical testing of the first and second III-V compound semiconductors are compared.
FILED Tuesday, April 24, 2018
APPL NO 15/961072
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/263 (20130101)
H01L 22/14 (20130101) Original (OR) Class
H01L 22/34 (20130101)
H01L 23/552 (20130101)
H01L 29/402 (20130101)
H01L 29/2003 (20130101)
H01L 29/7786 (20130101)
H01L 29/7787 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784245 Jessen
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Gregg H Jessen (Beavercreek, Ohio)
ABSTRACT An integrated circuit is provided including a first substrate with a first thermal conductivity. An active layer is deposited on the first substrate. At least one native device is fabricated on the active layer. A window is formed in the active layer, which exposes a portion of the first substrate. A non-native device is fabricated on a second substrate with a second thermal conductivity lower than the first thermal conductivity. The non-native device is flip-chip mounted in the widow on the first substrate and electrically connected to the at least one native device. The non-native device is also thermally connected to the first substrate such that heat generated by the non-native device is removed through the first substrate.
FILED Monday, June 10, 2019
APPL NO 16/435666
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/147 (20130101)
H01L 23/373 (20130101)
H01L 23/3731 (20130101)
H01L 23/3732 (20130101)
H01L 24/13 (20130101)
H01L 24/16 (20130101)
H01L 24/17 (20130101)
H01L 25/18 (20130101) Original (OR) Class
H01L 2224/13139 (20130101)
H01L 2224/13144 (20130101)
H01L 2224/13147 (20130101)
H01L 2224/16145 (20130101)
H01L 2224/16227 (20130101)
H01L 2924/01029 (20130101)
H01L 2924/01079 (20130101)
H01L 2924/14215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784387 Chanda et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S) Debashis Chanda (Oviedo, Florida);  Alireza Safaei (Orlando, Florida);  Michael Leuenberger (Orlando, Florida)
ABSTRACT A method is for making an optical detector device. The method may include forming a reflector layer carried by a substrate, forming a first dielectric layer over the reflector layer, and forming a graphene layer over the first dielectric layer and having a perforated pattern therein.
FILED Tuesday, April 02, 2019
APPL NO 16/372636
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)
B82Y 30/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/553 (20130101)
G01N 21/554 (20130101)
G01N 2021/7773 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/008 (20130101)
G02B 5/12 (20130101)
G02B 5/0866 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/307 (20130101)
H01L 31/09 (20130101)
H01L 31/101 (20130101)
H01L 31/0232 (20130101)
H01L 31/0328 (20130101)
H01L 31/0543 (20141201)
H01L 31/02327 (20130101)
H01L 31/035209 (20130101) Original (OR) Class
H01L 51/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784549 Tomasic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Boris Tomasic (Harvard, Massachusetts);  Carl R. Pfeiffer (Beavercreek, Ohio);  Thomas P. Steffen (Xenia, Ohio)
ABSTRACT An ultra-wideband linear-to-circular polarizer is disclosed. In accordance with embodiments of the invention, the polarizer includes a plurality of cascaded waveplates having biaxial permittivity or cascaded anisotropic sheet impedances. Each waveplate/sheet has a principal axis rotated at different angles relative to an adjacent waveplate/sheet about a z-axis of a 3-dimensional x, y, z coordinate system. Each waveplate is composed of a unit cell of an artificial anisotropic dielectric. Each sheet impedance is composed of an anisotropic metallic pattern. The polarizer further includes impedance matching layers disposed adjacent the cascaded waveplates/sheets.
FILED Tuesday, November 13, 2018
APPL NO 16/189602
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/286 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/17 (20130101) Original (OR) Class
H01P 1/171 (20130101)
H01P 1/172 (20130101)
H01P 1/173 (20130101)
H01P 11/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/40 (20130101)
H01Q 3/2676 (20130101)
H01Q 5/335 (20150115)
H01Q 15/04 (20130101)
H01Q 15/24 (20130101)
H01Q 15/244 (20130101)
H01Q 15/246 (20130101)
H01Q 21/0031 (20130101)
H01Q 21/064 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784848 Jariwala et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Regent of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Deep M. Jariwala (Evanston, Illinois);  Vinod K. Sangwan (Syracuse, New York);  Weichao Xu (Minneapolis, Minnesota);  Hyungil Kim (Woodbury, Minnesota);  Tobin J. Marks (Evanston, Illinois);  Mark C. Hersam (Wilmette, Illinois)
ABSTRACT Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies.
FILED Tuesday, November 19, 2019
APPL NO 16/688714
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/283 (20130101)
H01L 27/286 (20130101)
H01L 29/78693 (20130101)
H01L 51/0003 (20130101)
H01L 51/0017 (20130101)
H01L 51/0048 (20130101)
H01L 51/105 (20130101)
H01L 51/0545 (20130101)
H01L 51/0562 (20130101)
H01L 2251/303 (20130101)

Pulse Technique
H03K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784859 Chandrasekaran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Sriram Chandrasekaran (Lucas, Texas);  Michael S. Hockema (Plano, Texas)
ABSTRACT A gate drive circuit for generating asymmetric drive voltages comprises a gate drive transformer comprising: a primary winding responsive to a pulse width module (PWM) input signal to generate a bipolar signal having a positive bias voltage and a negative bias voltage; and a secondary winding responsive to the bipolar signal to generate a PWM output signal. A first charge pump is connected to the secondary winding responsive to the PWM output signal to generate a level shifted PWM output signal. A second charge pump is connected to the secondary winding to generate a readjusted PWM output signal by decreasing at least a portion of the level shifted PWM output signal. A gate switching device is connected to the first charge pump and second charge pump. A level shifted PWM output signal establishes an ON condition and the readjusted PWM output signal establishes an OFF condition of the gate MOSFET.
FILED Tuesday, July 23, 2019
APPL NO 16/520253
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/1608 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/07 (20130101)

Amplifiers
H03F 3/2171 (20130101)

Pulse Technique
H03K 17/06 (20130101)
H03K 17/063 (20130101)
H03K 17/567 (20130101)
H03K 17/691 (20130101)
H03K 17/6871 (20130101) Original (OR) Class
H03K 2217/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785191 Jordan
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) MCAFEE, LLC (Santa Clara, California)
ASSIGNEE(S) McAfee, LLC (Santa Clara, California)
INVENTOR(S) Christopher J. Jordan (Leesburg, Virginia)
ABSTRACT A router includes a processor-readable medium including code representing instructions to cause a processor to perform operations. The operations include routing received information communicated from a first network to a component associated with a service within a second network, responsive to a determination that the received information is to be handled by a service that exists within the second network. The operations also include routing the received information to a predetermined component, responsive to a determination that the received information is to be handled by a service that does not exist within the second network.
FILED Monday, October 23, 2017
APPL NO 15/791144
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0227 (20130101)
H04L 63/0245 (20130101) Original (OR) Class
H04L 63/1416 (20130101)
H04L 63/1491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785697 Hung
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) THE AEROSPACE CORPORATION (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) George W. Hung (Laguna Hills, California)
ABSTRACT In conventional MANETs, the functions of network discovery, route generation, and packets forwarding are performed at each node of the network. As a result, achieving routing convergence between all of the devices can be very time and resource intensive as no single node has a complete topology of the network. In contrast, the disclosed MANET with SDN architecture performs network discovery and route generation at centralized location, and packets forwarding is done separately at the node level. This new architecture allows the disclosed MANET to quickly adjust network operating characteristics whenever there is a change in the network topology. Additionally, since all network discovery and routing determination are performed centrally at a single controller, the disclosed MANET can generate a complete topology of the network and as such can perform channel provisioning between all devices such that co-channel interference, transmission delay, inefficient bandwidth allocation, and excessive retransmission are substantially reduced.
FILED Tuesday, July 24, 2018
APPL NO 16/044165
ART UNIT 2471 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/54 (20130101)

Wireless Communication Networks
H04W 40/04 (20130101) Original (OR) Class
H04W 40/20 (20130101)
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785745 Alvarez Icaza Rivera et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Rodrigo Alvarez Icaza Rivera (San Jose, California);  John V. Arthur (Mountain View, California);  Andrew S. Cassidy (San Jose, California);  Bryan L. Jackson (Fremont, California);  Paul A. Merolla (Palo Alto, California);  Dharmendra S. Modha (San Jose, California);  Jun Sawada (Austin, Texas)
ABSTRACT Embodiments of the invention provide a system for scaling multi-core neurosynaptic networks. The system comprises multiple network circuits. Each network circuit comprises a plurality of neurosynaptic core circuits. Each core circuit comprises multiple electronic neurons interconnected with multiple electronic axons via a plurality of electronic synapse devices. An interconnect fabric couples the network circuits. Each network circuit has at least one network interface. Each network interface for each network circuit enables data exchange between the network circuit and another network circuit by tagging each data packet from the network circuit with corresponding routing information.
FILED Tuesday, December 19, 2017
APPL NO 15/847530
ART UNIT 2126 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/049 (20130101)
G06N 3/063 (20130101)

Wireless Communication Networks
H04W 64/00 (20130101)
H04W 68/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785858 Kaminer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ido Kaminer (Cambridge, Massachusetts);  Liang Jie Wong (Singapore, Singapore);  Ognjen Ilic (Pasdena, California);  Yichen Shen (Cambridge, Massachusetts);  John Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT An apparatus includes at least one conductive layer, an electromagnetic (EM) wave source, and an electron source. The conductive layer has a thickness less than 5 nm. The electromagnetic (EM) wave source is in electromagnetic communication with the at least one conductive layer and transmits a first EM wave at a first wavelength in the at least one conductive layer so as to generate a surface plasmon polariton (SPP) field near a surface of the at least one conductive layer. The electron source propagates an electron beam at least partially in the SPP field so as to generate a second EM wave at a second wavelength less than the first wavelength.
FILED Wednesday, February 03, 2016
APPL NO 15/014401
ART UNIT 2884 — Optics
CURRENT CPC
X-ray Technique
H05G 2/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10780178 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Jiang Zhu (San Diego, California);  Linling He (San Diego, California)
ABSTRACT The present invention provides novel scaffolded HIV-1 vaccine immunogens. Some of the scaffolded immunogens contain a soluble gp140 trimer linked to the N-terminus of the nanoparticle subunit and a T-helper epitope that is fused via a short peptide spacer to the C-terminus of the nanoparticle subunit. Some other immunogens of the invention contain a soluble gp140 trimer protein that is linked to a stable nanoparticle via a short peptide spacer that is a T-helper epitope. Some of the scaffolded immunogens contain a gp140 trimer immunogen presented on a nanoparticle platform formed with I3-01 protein, E2p, or variants of protein 1VLW. Also provided in the invention are nucleic acids that encode the various vaccine immunogens described herein, and expression vectors and host cells harboring the nucleic acids. The invention further provides methods of using the scaffolded HIV-1 vaccine immunogens for preventing or treating HIV infections.
FILED Wednesday, October 31, 2018
APPL NO 16/177165
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 38/162 (20130101)
A61K 39/12 (20130101)
A61K 39/21 (20130101)
A61K 47/69 (20170801)
A61K 47/646 (20170801) Original (OR) Class
A61K 2039/57 (20130101)
A61K 2039/575 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55561 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/162 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16023 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780612 Lind et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) U T-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Randall F. Lind (Loudon, Tennessee);  Brian K. Post (Knoxville, Tennessee);  Phillip C. Chesser (Knoxville, Tennessee);  Andrew P. Reis (Knoxville, Tennessee);  Alex C. Roschli (Kingston, Tennessee)
ABSTRACT A method 100 for generating and dispensing a powdered 60 release agent during an additive manufacturing build is disclosed. A solid body 28 of release agent material is ground insitu by a grinder 50 and dispensed on a surface of the part 72 to prevent adhesion of an adjacent layer of a base material 70. With the addition of the powdered 60 release agent, a support structure 76 is easily separated from the base material 70 when the part 72 is complete, saving time and preventing the part 72 from sustaining unintentional damage. Since no powdered 60 release agent is actually loaded or stored in the apparatus 20, the potential for spillage, waste, inconsistent dispensing, inadvertent dispensing, and clumping due to humidity is eliminated.
FILED Tuesday, August 21, 2018
APPL NO 16/106270
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 37/0071 (20130101) Original (OR) Class
B29C 64/40 (20170801)
B29C 64/205 (20170801)
B29C 64/255 (20170801)
B29C 64/314 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780954 Sanders et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico);  Chevron U.S.A. Inc. (San Ramon, California)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico);  Chevron U.S.A. Inc. (San Ramon, California)
INVENTOR(S) Ryan Sanders (Houston, Texas);  Robert Kwan Meng Seah (Cypress, Texas);  Jolly James (Katy, Texas);  Bill Ward (Los Alamos, New Mexico)
ABSTRACT A system can include at least one measuring device that captures and collects multiple two-dimensional images of a mooring line disposed in water. The system can also include a mooring line assessment system that includes a controller communicably coupled to the at least one measuring device. The controller can receive the two-dimensional images from the at least one measuring device. The controller can also generate a three-dimensional reconstruction of the mooring line based on the two-dimensional images. The controller can further present the three-dimensional reconstruction to a user. The two-dimensional images can be captured and the recommendation can be made while the mooring line is in situ.
FILED Tuesday, March 26, 2019
APPL NO 16/364929
ART UNIT 3619 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 21/50 (20130101) Original (OR) Class
B63B 35/44 (20130101)
B63B 2021/505 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780997 Bigelow et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Josiah Bigelow (Albuquerque, New Mexico);  Brandon Toepper (Rio Rancho, New Mexico)
ABSTRACT A shock-resistant memory device comprises a housing and a memory module. The memory module is disposed within the housing and surrounded by potting material to protect the memory module from damage during a shock event. The housing can include a port that accommodates a data connection between the memory module and a sensor from which data is desirably received by the memory module. During a shock event the connection between the memory module and the sensor may be severed, but data stored in the memory module can be retained in the memory module which is protected by the housing. To facilitate retrieval of the memory device subsequent to a shock event, a balloon can be affixed to the housing. The balloon can be configured to inflate subsequent to the shock event so that the shock-resistant memory device does not sink in water and to make the memory device more visible for recovery.
FILED Tuesday, July 02, 2019
APPL NO 16/460388
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/10 (20130101)
B64G 1/52 (20130101) Original (OR) Class
B64G 1/62 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/04 (20130101)
H05K 5/061 (20130101)
H05K 5/064 (20130101)
H05K 5/069 (20130101)
H05K 5/0239 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781195 Dumesic et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) James A. Dumesic (Verona, Wisconsin);  Ali Hussain Motagamwala (Madison, Wisconsin)
ABSTRACT A method to produce 5-hydroxymethylfurfural (HMF) from C6 carbohydrates. The method includes the steps of reacting a reactant comprising at least one C6 carbohydrate, in a reaction mixture comprising at least about 5% (v/v) water, a polar, aprotic solvent, and an acid, for a time, at a temperature, and at a hydrogen ion concentration wherein at least a portion of the C6 carbohydrate present in the reactant is converted to 5-hydroxymethyl furfural (“HMF”).
FILED Tuesday, July 31, 2018
APPL NO 16/050522
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 307/50 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781196 Saha et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Basudeb Saha (Newark, Delaware);  Sunitha Sadula (Newark, Delaware);  Dionisios Vlachos (Voorhees, New Jersey)
ASSIGNEE(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S) Basudeb Saha (Newark, Delaware);  Sunitha Sadula (Newark, Delaware);  Dionisios Vlachos (Voorhees, New Jersey)
ABSTRACT A method of converting a lignocellulosic biomass to monosaccharides, and optionally further converting the monosaccharides to one or both of furfural and HMF, includes contacting the biomass with a reactive liquid phase comprising LiBr, H2SO4, and water, wherein H2SO4 preferably constitutes at most 1.0 wt %, more preferably at most 0.5 wt %, and most preferably at most 0.1 wt % of the reactive liquid phase, and water preferably constitutes at most at most 60 wt %, more preferably at most 50 wt %, and most preferably at most 30 wt % of the reactive liquid phase.
FILED Tuesday, August 15, 2017
APPL NO 16/323000
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 307/50 (20130101) Original (OR) Class

Derivatives of Natural Macromolecular Compounds
C08H 8/00 (20130101)

Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101)
C13K 13/002 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/125 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781294 Nash et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
INVENTOR(S) Landon D. Nash (Sunnyvale, California);  Duncan J. Maitland (College Station, Texas);  Nicole Docherty (Trop, Michigan);  Thomas S. Wilson (San Leandro, California);  Ward Small, IV (Livermore, California);  Jason Ortega (Pacifica, California);  Pooja Singhal (Redwood City, California)
ABSTRACT An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein.
FILED Friday, July 22, 2016
APPL NO 15/746471
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 24/0036 (20130101)
A61L 24/046 (20130101)
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/14 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)
A61L 2430/36 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/62 (20130101)
B05D 3/144 (20130101)
B05D 7/02 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/5663 (20130101)
B29C 59/14 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2033/04 (20130101)
B29K 2069/00 (20130101)
B29K 2075/00 (20130101)
B29K 2077/00 (20130101)
B29K 2995/0093 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/18 (20130101)
B32B 27/06 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/36 (20130101)
C08J 9/365 (20130101) Original (OR) Class
C08J 2201/026 (20130101)
C08J 2205/04 (20130101)
C08J 2207/10 (20130101)
C08J 2375/04 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781315 Saha et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Sourabh Kumar Saha (Livermore, California);  James Spencer Oakdale (Castro Valley, California)
ABSTRACT According to one embodiment, a method includes contacting a triiodobenzoic acid with an oxalyl chloride in a solvent whereby triiodobenzoyl chloride is formed, contacting diethanolamine with triiodobenzoyl chloride where triiodobenzoic diol amine is formed, and forming an acrylate of triiodobenzoic diol amine with acryloyl chloride where an organoiodine compound is formed. According to another embodiment, an optically clear photopolymer resist blend for additive manufacturing includes a radiopaque pre-polymer compound where the compound includes at least one of the following: iodine, bromine, tin, lead, or bismuth. The resist blend also includes a photoinitiator, a polymerization inhibitor, and a base pre-polymer.
FILED Thursday, December 01, 2016
APPL NO 15/367069
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Acyclic or Carbocyclic Compounds
C07C 51/60 (20130101)
C07C 51/60 (20130101)
C07C 63/70 (20130101)
C07C 231/02 (20130101)
C07C 231/02 (20130101)
C07C 231/12 (20130101)
C07C 231/12 (20130101)
C07C 233/69 (20130101)
C07C 233/69 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/18 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 4/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781525 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Sheng Dai (Knoxville, Tennessee);  Xiao-Guang Sun (Knoxville, Tennessee)
ABSTRACT An ionic liquid composition comprising a complex of a trihalo aluminum (III) species with at least one organic uncharged ligand comprising a ring structure having at least three ring carbon atoms and at least one ring heteroatom selected from nitrogen and sulfur, wherein the complex is a liquid at a temperature of 100° C. or less. Methods of electroplating aluminum onto a metallic substrate using the above-described ionic liquid composition are also described.
FILED Monday, December 10, 2018
APPL NO 16/214436
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 2/22 (20130101)
C07C 45/56 (20130101)
C07C 45/562 (20130101)
C07C 45/567 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/44 (20130101)
C25D 3/665 (20130101) Original (OR) Class
C25D 5/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781680 Ciezobka et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S) GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S) Jordan Ciezobka (Addison, Illinois);  Sarah Eisenlord (Libertyville, Illinois);  Debotyam Maity (Schaumburg, Illinois)
ABSTRACT A system and method for detecting and quantifying proppant for optimized fracture treatment design in in-fill and new wells. Proppant is isolated from drilling fluids and then analyzed to determine whether a formation within the well has been properly stimulated based on the analysis. Placement of an in-fill well may be based upon the determination of whether the well has been properly stimulated.
FILED Thursday, February 08, 2018
APPL NO 15/892081
ART UNIT 3619 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 21/065 (20130101)
E21B 43/267 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/34 (20130101)
G01N 15/0205 (20130101)
G01N 15/0227 (20130101)
G01N 15/1475 (20130101)
G01N 21/29 (20130101)
G01N 21/33 (20130101)
G01N 21/35 (20130101)
G01N 27/72 (20130101)
G01N 33/2823 (20130101)
G01N 2015/1486 (20130101)
G01N 2015/1493 (20130101)
G01N 2015/1497 (20130101)
G01N 2021/3155 (20130101)
G01N 2201/10 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/1603 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782014 Habib
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Youssef M Habib (Lancaster, Pennsylvania)
ASSIGNEE(S) Habib Technologies LLC (Lancaster, Pennsylvania)
INVENTOR(S) Youssef M Habib (Lancaster, Pennsylvania)
ABSTRACT The present invention is related to using a plasmonic energy conversion device comprised of a non-permeable substrate and of a plurality of nanorods, either free standing or embedded in aluminum matrix, that utilizes plasmons to generate vapor from a fluid as a result of being exposed to radiation. Methods of manufacturing the plasmonic energy converter device are described.
FILED Monday, November 13, 2017
APPL NO 15/810341
ART UNIT 2881 — Optics
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/02 (20130101)
C02F 1/10 (20130101)
C02F 1/14 (20130101)
C02F 2201/009 (20130101)
C02F 2305/08 (20130101)

Methods of Steam Generation; Steam Boilers
F22B 1/006 (20130101) Original (OR) Class

Solar Heat Collectors; Solar Heat Systems
F24S 10/00 (20180501)
F24S 70/10 (20180501)

Optical Elements, Systems, or Apparatus
G02B 5/008 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/053 (20141201)
H01L 31/035227 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782036 Martin
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Energy and Environmental Research Center Foundation (Grand Forks, North Dakota)
ASSIGNEE(S) Energy and Environmental Research Center (Grand Forks, North Dakota)
INVENTOR(S) Christopher L. Martin (Grand Forks, North Dakota)
ABSTRACT A heat dissipation system apparatus and method of operation using hygroscopic working fluid for use in a wide variety of environments for absorbed water in the hygroscopic working fluid to be released to minimize water consumption in the heat dissipation system apparatus for effective cooling in environments having little available water for use in cooling systems. The system comprises a low-volatility, hygroscopic working fluid to reject thermal energy directly to ambient air. The low-volatility and hygroscopic nature of the working fluid prevents complete evaporation of the fluid and a net consumption of water for cooling, and direct-contact heat exchange allows for the creation of large interfacial surface areas for effective heat transfer. Specific methods of operation prevent the crystallization of the desiccant from the hygrosopic working fluid under various environmental conditions.
FILED Thursday, June 08, 2017
APPL NO 15/617619
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 3/1417 (20130101) Original (OR) Class

Steam or Vapour Condensers
F28B 9/06 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction
F28C 1/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782052 Khalifa
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Hussein Ezzat Khalifa (Manlius, New York)
ASSIGNEE(S) SYRACUSE UNIVERSITY (Syracuse, New York)
INVENTOR(S) Hussein Ezzat Khalifa (Manlius, New York)
ABSTRACT A micro environmental control system that can remove or add 30W from or to the near range personal microenvironment of a user. For cooling, the μX uses a micro vapor compression system during the un-occupied period to freeze a phase-change-material in a thermal storage module. A fan then moves air over the phase-change-material to deliver cooled air. Heating is delivered by a small electric heater integrated into a condensing unit. The resulting system is inexpensive to build and uses a limited amount of energy.
FILED Wednesday, August 26, 2015
APPL NO 15/507065
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 13/00 (20130101)
F25B 21/02 (20130101) Original (OR) Class
F25B 2313/0293 (20130101)
F25B 2339/042 (20130101)
F25B 2400/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782193 Byvank et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Tom Byvank (Knoxville, Tennessee);  Benjamin S. Conner (Columbus, Ohio);  Roger A. Kisner (Knoxville, Tennessee);  Michael A. McGuire (Knoxville, Tennessee);  Orlando Rios (Knoxville, Tennessee);  Michael S. Kesler (Knoxville, Tennessee);  Gerard M. Ludtka (Oak Ridge, Tennessee);  Boyd Evans (Sewanee, Tennessee);  Cajetan Ikenna Niebedim (Ames, Iowa);  Ralph William McCallum (Santa Fe, New Mexico)
ABSTRACT An example apparatus can comprise an emitter to emit radio frequency radiation, an absorber that changes temperature based on emissions from the emitter, and one or more sensors to measure a temperature difference between a sample and a reference coupled to the absorber.
FILED Friday, September 01, 2017
APPL NO 15/694708
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 7/02 (20130101)
G01K 17/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782973 Bertolli et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Carlo Bertolli (Dobbs Ferry, New York);  John Kevin Patrick O'Brien (South Salem, New York);  Alexandre E Eichenberger (Chappaqua, New York);  Zehra Noman Sura (Yorktown Heights, New York)
ABSTRACT A method includes a computer device receiving a branch instruction; the computer device managing two tables, where a first table relates to application blocks and a second table relates to available address slots; and the computer device calculating a target of the branch instruction using a branch-to-link register, the computer device optimizes re-wiring in a cache using the calculation and the managed two tables.
FILED Thursday, May 14, 2015
APPL NO 14/712253
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3802 (20130101) Original (OR) Class
G06F 12/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783247 Steinfadt et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Shannon Steinfadt (Los Alamos, New Mexico);  Taina Immonen (Frederick, Maryland);  Thomas Leitner (Los Alamos, New Mexico);  Michael Kyle (Los Alamos, New Mexico)
ABSTRACT Software, such as malware, may be classified using phylogenetic techniques. An evolutionary history of a representative set of software programs may be reconstructed to generate a reference phylogeny. Dynamic traces of the representative software programs may be obtained. The dynamic traces may include time-ordered sequences of execution commands extracted from running software binaries. Metrics may be developed using the dynamic traces. One or more unknown software programs may then be classified against the reference phylogeny using the metrics developed using the dynamic traces of the representative set of software programs.
FILED Thursday, December 14, 2017
APPL NO 15/841408
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/564 (20130101)
G06F 21/566 (20130101) Original (OR) Class
G06F 2221/033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784045 Deligianni et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Hariklia Deligianni (Alpine, New Jersey);  William J. Gallagher (Ardsley, New York);  Sathana Kitayaporn (Portland, Oregon);  Eugene J. O'Sullivan (Nyack, New York);  Lubomyr T. Romankiw (Briancliff Manor, New York);  Naigang Wang (Ossining, New York);  Joonah Yoon (Fishkill, New York)
ABSTRACT A technique relates to a method of forming a laminated multilayer magnetic structure. An adhesion layer is deposited on a substrate. A magnetic seed layer is deposited on top of the adhesion layer. Magnetic layers and non-magnetic spacer layers are alternatingly deposited such that an even number of the magnetic layers is deposited while an odd number of the non-magnetic spacer layers is deposited. The odd number is one less than the even number. Every two of the magnetic layers is separated by one of the non-magnetic spacer layers. The first of the magnetic layers is deposited on the magnetic seed layer, and the magnetic layers each have a thickness less than 500 nanometers.
FILED Tuesday, September 15, 2015
APPL NO 14/854523
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 5/003 (20130101)
H01F 10/3204 (20130101)
H01F 41/043 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784097 Shelley et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana);  KENT STATE UNIVERSITY (Kent, Ohio)
ASSIGNEE(S) Indiana University Research And Technology Corporation (Indianapolis, Indiana);  Kent State University (Kent, Ohio)
INVENTOR(S) Jacob T. Shelley (Troy, New York);  Kelsey L. Williams (Kent, Ohio);  Gary M. Hieftje (Bloomington, Indiana);  Andrew J. Schwartz (Williamsville, New York)
ABSTRACT A solution-cathode glow discharge (SCGD) spectrometry apparatus may comprise an SCGD source and a mass or ion mobility spectrometer. A method for ionizing a molecular analyte may comprise contacting the molecular analyte with a plasma discharge to form ions and separating the ions in a mass spectrometer or ion mobility spectrometer. The contacting step may occur under atmospheric pressure and/or ambient conditions. The molecular analyte may be fragmented by the plasma discharge.
FILED Sunday, August 28, 2016
APPL NO 15/756011
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/622 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/145 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784104 Eastman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Jeffrey A. Eastman (Argonne, Illinois);  Boyd W. Veal (Argonne, Illinois);  Peter Zapol (Argonne, Illinois)
ABSTRACT Systems and methods of reversibly controlling the oxygen vacancy concentration and distribution in oxide heterostructures consisting of electronically conducting In2O3 films grown on ionically conducting Y2O3-stabilized ZrO2 substrates. Oxygen ion redistribution across the heterointerface is induced using an applied electric field oriented in the plane of the interface, resulting in controlled oxygen vacancy (and hence electron) doping of the film and possible orders-of-magnitude enhancement of the film's electrical conduction. The reversible modified behavior is dependent on interface properties and is attained without cation doping or changes in the gas environment in contact with the sample.
FILED Friday, June 08, 2018
APPL NO 16/004175
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/182 (20130101)
H01L 21/02241 (20130101) Original (OR) Class
H01L 21/28264 (20130101)
H01L 21/28581 (20130101)
H01L 45/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784391 Moore et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Duncan T. Moore (Fairport, New York);  Greg R. Schmidt (Gates, New York)
ABSTRACT A light guide includes a light guide layer having a transversely oriented side-end surface that forms a primary output aperture (exit) for light traveling in a forward propagation direction out of the end surface of the light guide (for, e.g., CPV applications) and, which forms a primary input aperture (entrance) for light traveling in a rearward propagation direction into the end surface of the light guide (for, e.g., illuminator applications). A light collection and concentration system includes a light guide apparatus, a light-transmitting medium layer disposed immediately adjacent the single light guide apparatus, and a light concentrator component of multiple optical array layers disposed adjacent the light transmitting medium layer, which is in optical registration with a light injection layer of the light guide apparatus.
FILED Thursday, December 08, 2016
APPL NO 15/372975
ART UNIT 2883 — Optics
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0543 (20141201)
H01L 31/0547 (20141201) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784492 Onnerud et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
ASSIGNEE(S) Cadenza Innovation, Inc. (Wilton, Connecticut)
INVENTOR(S) Tord Per Jens Onnerud (Wilton, Connecticut);  Jay Jie Shi (Acton, Massachusetts)
ABSTRACT Casings for lithium ion batteries are provided that include a container or assembly that defines a base, side walls and a top or lid, and a vent structure associated with the container or assembly. A flame arrestor may be positioned in proximity to the vent structure. The lithium ion battery may also include a pressure disconnect device associated with the casing. The pressure disconnect device may include a deflectable dome-based activation mechanism, and the deflectable dome-based activation mechanism may be configured and dimensioned to prevent burn through, e.g., by increasing the mass of the dome-based activation mechanism, adding material (e.g., foil) to the dome-based activation mechanism, and combinations thereof. Burn through may also be avoided, at least in part, based on the speed at which the dome-based activation mechanism responds at a target trigger pressure.
FILED Wednesday, December 14, 2016
APPL NO 15/562792
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 3/0046 (20130101)
B60L 50/64 (20190201)
B60L 58/26 (20190201)
B60L 2240/545 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/043 (20130101)
H01M 2/206 (20130101)
H01M 2/0237 (20130101)
H01M 2/345 (20130101) Original (OR) Class
H01M 2/348 (20130101)
H01M 2/1077 (20130101)
H01M 2/1094 (20130101)
H01M 10/0525 (20130101)
H01M 2200/20 (20130101)
H01M 2200/103 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/705 (20130101)
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784511 Harrison et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Katharine Lee Harrison (Albuquerque, New Mexico);  Matthaeus Wolak (Albuquerque, New Mexico);  Michael P. Siegal (Albuquerque, New Mexico)
ABSTRACT Nanoporous carbon provides a binderless, three-dimensional form of graphene as an anode material for lithium-ion batteries.
FILED Monday, November 19, 2018
APPL NO 16/195371
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/62 (20130101)
H01M 4/366 (20130101)
H01M 4/587 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/021 (20130101)
H01M 2004/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784512 Sakshaug et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Group14 Technologies, Inc. (Woodinville, Washington)
ASSIGNEE(S) Group14 Technologies, Inc. (Woodinville, Washington)
INVENTOR(S) Avery J. Sakshaug (Everett, Washington);  Henry R. Costantino (Woodinville, Washington);  Aaron M. Feaver (Seattle, Washington);  Leah A. Thompkins (Seattle, Washington);  Katharine Geramita (Seattle, Washington);  Benjamin E. Kron (Seattle, Washington);  Sarah Fredrick (Seattle, Washington);  Farshid Afkhami (Lake Stevens, Washington);  Adam Strong (Lake Forest Park, Washington)
ABSTRACT Composites of silicon and various porous scaffold materials, such as carbon material comprising micro-, meso- and/or macropores, and methods for manufacturing the same are provided. The compositions find utility in various applications, including electrical energy storage electrodes and devices comprising the same.
FILED Friday, January 17, 2020
APPL NO 16/746697
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/522 (20130101)
C04B 35/524 (20130101)
C04B 38/0051 (20130101)
C04B 38/0054 (20130101)
C04B 38/0064 (20130101)
C04B 41/009 (20130101)
C04B 41/009 (20130101)
C04B 41/85 (20130101)
C04B 41/4529 (20130101)
C04B 41/5096 (20130101)
C04B 41/5096 (20130101)
C04B 2111/00853 (20130101)
C04B 2235/428 (20130101)
C04B 2235/616 (20130101)
C04B 2235/6581 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/133 (20130101)
H01M 4/134 (20130101)
H01M 4/362 (20130101)
H01M 4/364 (20130101)
H01M 4/366 (20130101)
H01M 4/386 (20130101)
H01M 4/0416 (20130101)
H01M 4/587 (20130101) Original (OR) Class
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
H01M 2004/021 (20130101)
H01M 2220/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784518 Mukerjee et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Sanjeev Mukerjee (Mansfield, Massachusetts);  Michael Bates (Lynn, Massachusetts);  Shraboni Ghoshal (Malden, Massachusetts);  Huong Thi Thanh Doan (West Roxbury, Massachusetts)
ABSTRACT The invention provides a nitrogen-functionalized platinum-transition metal catalyst having the formula Pt-M-NX/C (where M is a transition element such as Fe, Co, Ni, Nb, Ta, Ir, Rh, or Ru) for use at the hydrogen electrode of a hydrogen/bromine redox flow battery. The new catalyst possesses excellent activity and durability in the HBr/Br2 environment, showing superior resistance to halide poisoning than conventional Pt/C or Pt-M/C catalysts.
FILED Thursday, May 12, 2016
APPL NO 15/572563
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 11/04 (20130101)
C25B 11/0473 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/88 (20130101)
H01M 4/921 (20130101)
H01M 4/923 (20130101)
H01M 4/926 (20130101) Original (OR) Class
H01M 8/188 (20130101)
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/528 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784538 Chang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Fu Kuo Chang (Palo Alto, California);  Raphael Gerard Christian Nardari (Palo Alto, California);  Purim Ladpli (Palo Alto, California)
ABSTRACT Described here is a multifunctional energy storage (MES) composite comprising (a) a stack of energy storage materials and (b) one or more structural facesheets sandwiching the stack of energy storage materials, wherein the stack of battery materials is perforated by (c) one or more reinforcements, and wherein the reinforcements are bonded to the structural facesheets. Also described here is a MES composite comprising (a) a stack of energy storage materials, (b) one or more structural facesheets sandwiching the stack of energy storage materials, and (c) one or more reinforcements perforated by the stack of energy storage materials, wherein the reinforcements are bonded to the structural facesheets.
FILED Friday, February 05, 2016
APPL NO 15/549117
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/12 (20130101)
H01G 11/82 (20130101)
H01G 11/84 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/0257 (20130101)
H01M 2/0282 (20130101)
H01M 6/02 (20130101)
H01M 10/02 (20130101)
H01M 10/052 (20130101)
H01M 10/058 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0585 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784682 Baker et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Kyri Alysa Baker (Arvada, Colorado);  Andrey Bernstein (Golden, Colorado);  Emiliano Dall'Anese (Arvada, Colorado)
ABSTRACT The present disclosure provides techniques for network-cognizant droop control in power systems, such as a power distribution system. An example device includes a processor configured to determine, based on (i) a model representing a structure of a power system that includes a plurality of energy resources and (ii) an indication of predicted uncontrollable power injections in the power system, for each controllable energy resource in the plurality of energy resources, a respective value of a first droop coefficient and a respective value of a second droop coefficient. The processor may be further configured to cause at least one controllable energy resource in the plurality of energy resources to modify an output power of the at least one energy resource based on the respective value of the first droop coefficient and the respective value of the second droop coefficient.
FILED Friday, February 09, 2018
APPL NO 15/892730
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/06 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/003 (20200101)
H02J 3/16 (20130101)
H02J 3/32 (20130101)
H02J 3/48 (20130101)
H02J 3/50 (20130101)
H02J 3/381 (20130101)
H02J 3/382 (20130101)
H02J 3/383 (20130101)
H02J 3/1892 (20130101) Original (OR) Class
H02J 2203/20 (20200101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 40/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784686 Schneider et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Kevin P. Schneider (Seattle, Washington);  Francis K. Tuffner (Seattle, Washington);  Jacob Hansen (Seattle, Washington);  Yingying Tang (Richland, Washington);  Nikitha Radhakrishnan (Richland, Washington);  Priya Thekkumparambath Mana (Richland, Washington)
ABSTRACT Apparatus and methods are disclosed for control systems for improving stability of electrical grids by temporarily reducing voltage output of electrical generators responsive to transient events on an electrical grid. In one example of the disclosed technology, a controller is coupled is to an automatic voltage regulator, which in turn adjusts excitation current of an electrical generator responsive to changes in frequency detected for the electrical grid. Reducing the output voltage temporarily allows for smaller generators to provide power to the microgrid. Methods for selecting parameters determining how the controller generates a regulation signal used to adjust the excitation current are further disclosed.
FILED Friday, January 19, 2018
APPL NO 15/875981
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/24 (20130101)
H02J 3/381 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785237 Mestha et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Lalit Keshav Mestha (North Colonie, New York);  Masoud Abbaszadeh (Clifton Park, New York);  Annarita Giani (Niskayuna, New York)
ABSTRACT Streams of monitoring node signal values over time, representing a current operation of the industrial asset, are used to generate current monitoring node feature vectors. Each feature vector is compared with a corresponding decision boundary separating normal from abnormal states. When a first monitoring node passes a corresponding decision boundary, an attack is detected and classified as an independent attack. When a second monitoring node passes a decision boundary, an attack is detected and a first decision is generated based on a first set of inputs indicating if the attack is independent/dependent. From the beginning of the attack on the second monitoring node until a final time, the first decision is updated as new signal values are received for the second monitoring node. When the final time is reached, a second decision is generated based on a second set of inputs indicating if the attack is independent/dependent.
FILED Friday, May 11, 2018
APPL NO 15/977558
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6217 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/005 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101) Original (OR) Class
H04L 63/1425 (20130101)
H04L 63/1441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785878 Girardi
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Michael Girardi (Kansas City, Missouri)
ABSTRACT A circuit board comprising a substrate and a circuit trace. The substrate includes a surface etched via ion milling over a circuit area such that the surface has an increased roughness. The circuit trace forms portions of an electronic circuit and may be created from a thin conductive film deposited on the surface within the circuit area. The circuit trace adheres more strongly to the roughened substrate surface, which prevents the circuit trace from peeling or becoming delaminated from the substrate surface.
FILED Friday, May 10, 2019
APPL NO 16/408772
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0298 (20130101)
H05K 1/0306 (20130101)
H05K 3/16 (20130101)
H05K 3/0017 (20130101)
H05K 3/027 (20130101)
H05K 3/146 (20130101)
H05K 3/381 (20130101) Original (OR) Class
H05K 2201/0317 (20130101)
H05K 2203/092 (20130101)
H05K 2203/0522 (20130101)
H05K 2203/0585 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10780413 Kung et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Yu-Chun Kung (South Pasadena, California);  Pei-Yu E. Chiou (Los Angeles, California);  Ting-Hsiang S. Wu (Culver City, California);  Yue Chen (Los Angeles, California);  Michael A. Teitell (Tarzana, California)
ABSTRACT Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel.
FILED Tuesday, August 28, 2018
APPL NO 16/115470
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101) Original (OR) Class
B01J 2219/00587 (20130101)
B01J 2219/00599 (20130101)
B01J 2219/00713 (20130101)
B01J 2219/00722 (20130101)
B01J 2219/00756 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0265 (20130101)
B01L 3/502784 (20130101)
B01L 7/52 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/086 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 35/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780419 Choi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Woongchul Choi (College Station, Texas);  Gang Yang (College Station, Texas);  Choongho Yu (College Station, Texas)
ABSTRACT Disclosed are non-noble element compositions of matter, structures, and methods for producing the catalysts that can catalyze oxygen reduction reactions (ORR). The disclosed composition of matter can be comprised of graphitic carbon doped with nitrogen and associated with one or two kinds of transition metals. The disclosed structure is a three dimensional, porous structure comprised of a plurality of the disclosed compositions of matter. The disclosed structure can be fashioned into an electrode of an electrochemical cell to serve as a diffusion layer and also to catalyze an ORR. Two methods are disclosed for producing the disclosed composition of matter and structure. The first method is comprised of two steps, and the second method is comprised of a single step.
FILED Tuesday, July 02, 2019
APPL NO 16/502011
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/185 (20130101) Original (OR) Class
B01J 23/745 (20130101)
B01J 35/0033 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/16 (20170801)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/90 (20130101)
H01M 4/96 (20130101)
H01M 4/8605 (20130101)
H01M 4/8867 (20130101)
H01M 12/08 (20130101)
H01M 2004/8689 (20130101)
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/128 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780438 Kamalakshakurup et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Gopakumar Kamalakshakurup (Irvine, California);  Abraham P. Lee (Irvine, California)
ABSTRACT An interfacial technique utilizes hydrodynamic micro-vortices to perform (i) high efficiency single cell encapsulation and (ii) size-selective capturing of cells based on their sizes in a single microfluidic device. A notable feature of this technique is that it can perform high efficiency single cell encapsulation at low cell concentrations, and this technique is all passive, controlled only by the flow rates of the two phases and does not require complex structures or on-chip active devices. Single bead/cell encapsulation was demonstrated at 50% efficiency, which is at least 10 times greater than the random encapsulations at the introduced cell concentrations. Also demonstrated is the selective trapping of cells based on their sizes. This present technique expands the capabilities of droplet microfluidics for applications ranging from single cell genomics, proteomic assays to sample preparation.
FILED Monday, June 11, 2018
APPL NO 16/005533
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1405 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502746 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101) Original (OR) Class
B01L 2200/141 (20130101)
B01L 2200/143 (20130101)
B01L 2200/0636 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/022 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101)
G01N 15/0255 (20130101)
G01N 2015/0053 (20130101)
G01N 2015/1006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781142 Li et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
ASSIGNEE(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S) Xiaodong Li (Charlottesville, Virginia);  Yunya Zhang (Charlottesville, Virginia)
ABSTRACT A graphene/metal-oxide hybrid reinforced composite and a method for a graphene/metal-oxide hybrid reinforced composite. The method includes freeze drying a slurry comprising graphene oxide and flakes to form a flake-graphene oxide foam. The graphene/metal-oxide hybrid reinforced composite comprises graphene, metal, and metal oxide nanoparticles. The metal is arranged in parallel lamellar structure to form metal layers in the composite. The metal oxide nanoparticles are present at the interfaces between the metal layers and the graphene.
FILED Friday, August 19, 2016
APPL NO 15/753866
ART UNIT 1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0055 (20130101)
B22F 1/0059 (20130101)
B22F 9/026 (20130101)
B22F 9/026 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/00 (20170801)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/01 (20130101)
C04B 35/64 (20130101)
C04B 35/76 (20130101)
C04B 35/117 (20130101)
C04B 35/528 (20130101)
C04B 35/622 (20130101)
C04B 35/628 (20130101)
C04B 35/634 (20130101)
C04B 35/806 (20130101) Original (OR) Class
C04B 35/6265 (20130101)
C04B 35/62655 (20130101)
C04B 35/63416 (20130101)
C04B 2235/422 (20130101)
C04B 2235/781 (20130101)
C04B 2235/788 (20130101)
C04B 2235/5276 (20130101)
C04B 2235/5292 (20130101)
C04B 2235/5454 (20130101)

Alloys
C22C 1/08 (20130101)
C22C 1/1026 (20130101)
C22C 1/1026 (20130101)
C22C 26/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781213 Stoltz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Brian M. Stoltz (San Marino, California);  Eric R. Welin (Pasadena, California);  Scott C. Virgil (Pasadena, California);  Pamela Tadross (Natick, Massachusetts);  Gerit M. Pototschnig (San Diego, California);  Aurapat (Fa) Ngamnithiporn (Pasadena, California);  Kenji Negoro (Ibaraki, Japan);  Guillaume Lapointe (Basel, Switzerland);  Max Klatte (Loerrach, Germany);  Christopher Haley (Boston, Massachusetts);  Christian Gruenanger (Mannheim, Germany);  Emil Glibstrup (Copenhagen, Denmark);  Christopher Gilmore (Natick, Massachusetts);  Kevin McCormack Allan (Belmont, California)
ABSTRACT (−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.
FILED Friday, November 22, 2019
APPL NO 16/692518
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/04 (20130101)
C07D 471/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781221 Toutov et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Anton A. Toutov (Pasadena, California);  Kerry N. Betz (Boulder, Colorado);  Andrew M. Romine (San Diego, California);  Robert H. Grubbs (South Pasadena, California)
ABSTRACT The present disclosure is directed at methods of forming an N—Si silyl bond, the method comprising contacting an organic substrate comprising an aromatic amine having at least one N—H bond with a mixture comprising of (a) at least one hydrosilane or hydrosiloxane and (b) at least one hydroxide or alkoxide, under conditions sufficient to form the N—Si bond. The disclosure is further directed to the compositions involved in these methods and the products that result therefrom.
FILED Thursday, January 10, 2019
APPL NO 16/244637
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781509 Chopra et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Temple University-of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania);  UNIVERSITY OF MARYLAND (College Park, Maryland)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Harsh Deep Chopra (Philadelphia, Pennsylvania);  Manfred Wuttig (Silver Spring, Maryland)
ABSTRACT The invention relates to non-Joulian magnetostriction (NJM) materials comprising transition metals, such as iron alloy magnets with non-Joulian magnetostriction (NJM). The invention also relates to reversibly linear non-dissipative transition metals magnets. The materials are capable of simultaneously large actuation in longitudinal and transverse directions, without simultaneous heat loss. The invention relates as well to methods of making non-Joulian magnetostriction (NJM) materials.
FILED Friday, May 20, 2016
APPL NO 15/160705
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 38/002 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782135 Moldwin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric and Geospace Sciences (AGS)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Mark B. Moldwin (Ann Arbor, Michigan);  Lauro V. Ojeda (Ann Arbor, Michigan)
ABSTRACT A magnetic beacon and inertial sensor system for precise indoor localization is provided using active magnetic beacons, magnetometers and inertial measurement units. The system is designed to work in environments that are not conducive to radio frequency (RF) (such as GPS, cell, Wi-Fi, or Bluetooth) or optical techniques (CCTV, IR), such as inside heavy industrial plant settings, underground or underwater.
FILED Monday, April 10, 2017
APPL NO 16/092677
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/02 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 1/68 (20130101)

Wireless Communication Networks
H04W 64/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782233 Wang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Feng Wang (Berkeley, California);  Jason Horng (Berkeley, California);  Halleh B. Balch (Berkeley, California)
ABSTRACT An optical sensing system includes a planar optical waveguide having a first surface for detection and a second surface for coupling light. The optical sensing system includes a functional layer integral with the first surface of the planar optical waveguide, and a coupling layer in contact with the second surface of the planar optical waveguide, the coupling layer having a lower refractive index than the planar optical waveguide. The optical sensing system includes an optical source arranged to illuminate at least a portion of the second surface of the planar optical waveguide through the coupling layer with substantially critical optical coupling. The optical sensing system also includes an optical detector arranged to receive a portion of light from the optical source after being reflected from the first surface of the planar optical waveguide and passing through the coupling layer.
FILED Monday, March 13, 2017
APPL NO 15/521834
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/552 (20130101) Original (OR) Class
G01N 2021/436 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/155 (20130101)
G01R 29/14 (20130101)
G01R 29/0885 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782239 Humphrey
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Simon M. Humphrey (Austin, Texas)
ABSTRACT Embodiments of the present disclosure pertain to methods of monitoring an environment for the presence of a solvent by: (i) exposing the environment to a luminescent compound, where the relative luminescence emission intensity of the luminescent compound changes upon interaction with the solvent; and (ii) monitoring a change in the relative luminescence emission intensity of the luminescent compound, where the absence of the change indicates the absence of the solvent from the environment, and where the presence of the change indicates the presence of the solvent in the environment. The luminescent compounds include a phosphorous atom with one or more carboxyl groups, where the carboxyl groups are coordinated with one or more metallic ions (e.g., lanthanide ions and yttrium ions). The present disclosure also pertains to sensors for monitoring an environment for the presence of a solvent, where the sensors include one or more of the aforementioned luminescent compounds.
FILED Tuesday, May 10, 2016
APPL NO 15/572411
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/182 (20130101)
C09K 2211/1014 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/78 (20130101) Original (OR) Class
G01N 31/22 (20130101)
G01N 2021/7786 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782266 Crall et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The University of Tulsa (Tulsa, Oklahoma)
ASSIGNEE(S) The University of Tulsa (Tulsa, Oklahoma)
INVENTOR(S) Matthew Crall (Little Rock, Arkansas);  Samuel Laney (Tulsa, Oklahoma);  Michael Keller (Tulsa, Oklahoma)
ABSTRACT A method of making a fiber reinforced composite material having a two-part liquid solution forming magnetic nanoparticles. The method includes the steps of preparing a fiber reinforced composite having dispersed fibers and a polymer matrix and having a plurality of vascular channels therethrough. A first liquid solution is incorporated in at least one of the vascular channels and a second liquid solution is incorporated in at least one other of the vascular channels. When the liquid solutions are joined together because of damage or cracking to the composite, the liquids form a ferrous magnetic material. Non-destructive evaluation of internal damage to the fiber reinforced composite material may be accomplished by magnetic field disturbance detection, thermal detection, or visual detection.
FILED Tuesday, October 31, 2017
APPL NO 15/799462
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/88 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2309/08 (20130101)
B29K 2995/0008 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/8803 (20130101)
G01N 25/72 (20130101)
G01N 27/82 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782289 Ozdemir et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Sahin Kaya Ozdemir (St. Louis, Missouri);  Lan Yang (St. Louis, Missouri)
ABSTRACT A micro-resonator and fiber taper based sensing system, which uses mode splitting or frequency shift methods and polarization measurements for particle sensing.
FILED Thursday, November 02, 2017
APPL NO 15/801823
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1429 (20130101)
G01N 15/1434 (20130101)
G01N 15/1463 (20130101)
G01N 21/21 (20130101)
G01N 21/45 (20130101)
G01N 21/7746 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2015/0038 (20130101)
G01N 2015/1454 (20130101)
G01N 2021/458 (20130101)
G01N 2201/08 (20130101)
G01N 2201/0683 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782323 Parkhideh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of North Carolina Charlotte (Charlotte, North Carolina)
ASSIGNEE(S) University of North Carolina Charlotte (Charlotte, North Carolina)
INVENTOR(S) Babak Parkhideh (Charlotte, North Carolina);  Shahriar Jalal Nibir (Charlotte, North Carolina)
ABSTRACT Various examples are provided for contactless wideband current sensing. A combination of magnetoresistive (MR) sensor and Rogowski coil outputs can be combined to provide current sensing from DC to 10 MHZ or more. In one example, a system includes a MR sensor that can provide an MR output voltage corresponding to a magnitude of the current through a trace; a Rogowski coil sensor that can provide a Rogowski output voltage corresponding to a magnitude of the current; and processing circuitry configured to generate an output current signal by aggregating the MR and Rogowski output voltages. In another example, a method includes conditioning an output from a MR sensor disposed adjacent to a trace carrying a current; conditioning an output from a Rogowski coil disposed adjacent to the trace; and aggregating the first and second conditioned signals to provide an output current signal corresponding to the current passing through the trace.
FILED Friday, May 12, 2017
APPL NO 16/073542
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 15/181 (20130101)
G01R 15/205 (20130101) Original (OR) Class
G01R 19/0092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782610 Stowers et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Inpria Corporation (Corvallis, Oregon)
ASSIGNEE(S) Inpria Corporation (Corvallis, Oregon)
INVENTOR(S) Jason K. Stowers (Corvallis, Oregon);  Alan J. Telecky (Albany, Oregon);  Douglas A. Keszler (Corvallis, Oregon);  Andrew Grenville (Eugene, Oregon)
ABSTRACT Stabilized precursor solutions can be used to form radiation inorganic coating materials. The precursor solutions generally comprise metal suboxide cations, peroxide-based ligands and polyatomic anions. Design of the precursor solutions can be performed to achieve a high level of stability of the precursor solutions. The resulting coating materials can be designed for patterning with a selected radiation, such as ultraviolet light, x-ray radiation or electron beam radiation. The radiation patterned coating material can have a high contrast with respect to material properties, such that development of a latent image can be successful to form lines with very low line-width roughness and adjacent structures with a very small pitch.
FILED Monday, October 16, 2017
APPL NO 15/784258
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/20 (20130101)
G03F 7/0042 (20130101)
G03F 7/0043 (20130101) Original (OR) Class
G03F 7/327 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24355 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783764 Davis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Benjamin Davis (Columbia, South Carolina);  Juan M. Caicedo (Columbia, South Carolina)
ABSTRACT An impact detection methodology is disclosed. Systems and methods can be utilized to detect impacts of concern such as collisions, falls, or other incidents. Systems and methods can be utilized to monitor an area and detect falls or collisions of an individual, for instance, as may require intervention to aid the subject. A system can include two or more accelerometers and a controller. The accelerometers can be in communication with the structure (e.g., within or on the walls or floor of a structure) and can monitor the structure for vibrations. The accelerometers can be coupled to a controller that is configured to process data obtained from the accelerometers and provide output with regard to the force and/or location of an impact within the structure.
FILED Wednesday, April 19, 2017
APPL NO 15/491084
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 1/08 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 5/0052 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/14 (20130101)
G01N 29/045 (20130101)
G01N 29/48 (20130101)
G01N 29/4427 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/043 (20130101) Original (OR) Class
G08B 25/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784532 Rustomji et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) SOUTH 8 TECHNOLOGIES, INC. (San Diego, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) South 8 Technologies, Inc. (San Diego, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Cyrus Sam Rustomji (San Diego, California);  Yangyuchen Yang (La Jolla, California);  Daniel Davies (San Diego, California);  Jungwoo Lee (San Diego, California);  Ying Shirley Meng (San Diego, California)
ABSTRACT Chemical additives are disclosed to increase solubility of salts in liquefied gas electrolytes.
FILED Monday, October 28, 2019
APPL NO 16/666131
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/60 (20130101)
H01G 11/64 (20130101)
H01G 11/78 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101) Original (OR) Class
H01M 10/0567 (20130101)
H01M 10/0569 (20130101)
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784848 Jariwala et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Regent of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Deep M. Jariwala (Evanston, Illinois);  Vinod K. Sangwan (Syracuse, New York);  Weichao Xu (Minneapolis, Minnesota);  Hyungil Kim (Woodbury, Minnesota);  Tobin J. Marks (Evanston, Illinois);  Mark C. Hersam (Wilmette, Illinois)
ABSTRACT Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies.
FILED Tuesday, November 19, 2019
APPL NO 16/688714
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/283 (20130101)
H01L 27/286 (20130101)
H01L 29/78693 (20130101)
H01L 51/0003 (20130101)
H01L 51/0017 (20130101)
H01L 51/0048 (20130101)
H01L 51/105 (20130101)
H01L 51/0545 (20130101)
H01L 51/0562 (20130101)
H01L 2251/303 (20130101)

Pulse Technique
H03K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784970 Melodia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Emrecan Demirors (Boston, Massachusetts)
ABSTRACT Embodiments disclosed herein may be implemented in the form of a method or corresponding apparatus for receiving or transmitting network communications carried at acoustic wavelengths via an acoustic medium. The corresponding method or apparatus may include a gate-level digital hardware module communicatively coupled to a communications module and define therein logic blocks configured to perform respective primitive processing functions, sequences of the logic blocks being capable of processing data units in accordance with any of the multiple communications protocols on a data unit-by-data unit basis without reconfiguring. According to some embodiments, the gate-level digital hardware module may be configured to process a data unit in accordance with a first communications protocol by directing the data unit through a first sequence of logic blocks, and process a subsequent data unit in accordance with a second communications protocol by directing the subsequent data unit through a second of sequence logic blocks.
FILED Monday, October 23, 2017
APPL NO 15/791181
ART UNIT 2416 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 11/00 (20130101)
H04B 13/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10785545 Metzler et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Human Resource Development (HRD)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Richard E. L. Metzler (San Antonio, Texas);  Sos S. Agaian (San Antonio, Texas)
ABSTRACT Embodiments of reversible systems and methods for fast, secure and efficient transmission, storage, and protection of digital multimedia are disclosed. The embodiments may have the ability to simultaneously compress and encrypt digital data in order to concurrently reduce data size and prevent reconstruction without the proper encryption key. Embodiments of a method may include pre-processing data to optimize the size of data segments to be compressed, transforming the data for improving the compressibility of the before-mentioned data segments, processing the data sequentially to generate predictive statistical models, encoding the data for simultaneously encrypting and compressing data segments using a keystream, and increasing both the compression ratio and security of these encoding processes using a block cipher. Embodiments of these methods may be suitable for use on both encrypted and unencrypted media.
FILED Monday, April 22, 2013
APPL NO 14/395674
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/065 (20130101)
H04L 9/0618 (20130101)

Pictorial Communication, e.g Television
H04N 21/2343 (20130101)
H04N 21/2347 (20130101)
H04N 21/8458 (20130101)
H04N 21/64715 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10780514 DeMange et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Jeffrey J. DeMange (Cleveland, Ohio);  Frank J. Ritzert (North Ridgeville, Ohio);  Michael V. Nathal (Strongsville, Ohio);  Patrick H. Dunlap, Jr. (Strongsville, Ohio);  Bruce M. Steinetz (Westlake, Ohio)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Jeffrey J. DeMange (Cleveland, Ohio);  Frank J. Ritzert (North Ridgeville, Ohio);  Michael V. Nathal (Strongsville, Ohio);  Patrick H. Dunlap, Jr. (Strongsville, Ohio);  Bruce M. Steinetz (Westlake, Ohio)
ABSTRACT A process for forming a single crystal superalloy wave spring is provided. In one embodiment, the process may include machining a wave spring from a single crystal superalloy slab after optimizing its orientation using diffraction techniques so that the wave spring will exhibit optimal spring properties.
FILED Thursday, November 03, 2016
APPL NO 15/342221
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 21/005 (20130101)
B22D 27/04 (20130101)

Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal
B23H 9/001 (20130101) Original (OR) Class

Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 19/048 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 29/52 (20130101)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/18 (20130101)
F16F 1/021 (20130101)
F16F 2224/0208 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49609 (20150115)
Y10T 29/49989 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781517 Dwivedi
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Vivek H. Dwivedi (Glenn Dale, Maryland)
ABSTRACT Modification of pigments may be performed using atomic layer deposition (ALD) to provide custom-tailored thermal protection characteristics. More specifically, ALD may be used to encapsulate pigment particles with controlled thicknesses of a thermal protective layer, such as VO2. ALD may allow films to be theoretically grown one atom at a time, providing angstrom-level thickness control.
FILED Thursday, September 27, 2018
APPL NO 16/144242
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black;
C09C 3/063 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/56 (20130101)
C23C 16/405 (20130101)
C23C 16/4417 (20130101)
C23C 16/45527 (20130101)
C23C 16/45544 (20130101)
C23C 16/45553 (20130101)
C23C 16/45555 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782482 Stone et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Stone Aerospace, Inc. (Del Valle, Texas)
ASSIGNEE(S) Stone Aerospace, Inc. (Del Valle, Texas)
INVENTOR(S) William C. Stone (Del Valle, Texas);  Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT An optical energy transfer and conversion system comprising a fiber spooler and an electrical power extraction subsystem connected to the spooler with an optical waveguide. Optical energy is generated at and transferred from a base station through fiber wrapped around the spooler, and ultimately to the power extraction system at a remote mobility platform for conversion to another form of energy. The fiber spooler may reside on the remote mobility platform which may be a vehicle, or apparatus that is either self-propelled or is carried by a secondary mobility platform either on land, under the sea, in the air or in space.
FILED Monday, January 15, 2018
APPL NO 15/871754
ART UNIT 2883 — Optics
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 33/00 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 41/0085 (20130101)
E21B 47/135 (20200501)

Optical Elements, Systems, or Apparatus
G02B 6/3604 (20130101) Original (OR) Class
G02B 6/4268 (20130101)
G02B 6/4296 (20130101)
G02B 6/4415 (20130101)
G02B 6/4436 (20130101)
G02B 6/4458 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/30 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/025 (20130101)
H02J 50/30 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783288 Timar et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Architecture Technology Corporation (Hopkins, Minnesota)
ASSIGNEE(S) ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota)
INVENTOR(S) Sebastian Timar (Santa Cruz, California);  Matthew Stillerman (Ithaca, New York);  Douglas Sweet (Satatoga, California)
ABSTRACT A runway capacity forecast system includes machine instructions stored in a non-transitory computer readable storage medium, the machine instructions, when executed, causing a processor to access data items related to a runway of interest for a time horizon of interest, the data items comprising environment factors for the runway of interest and the time horizon of interest, flight operation factors, and aircraft performance factors for aircraft scheduled on the runway of interest and during the time horizon of interest; extract data elements from the data items; reformat the data elements as analyzable data elements and store the analyzable data elements in an analyzable data structure; apply a probabilistic model to selected ones of the analyzable data elements to provide a forecast runway capacity for the runway of interest during the time horizon of interest the first product; and using the forecast runway capacity, determine one or more impacts based on the forecast capacity.
FILED Tuesday, August 08, 2017
APPL NO 15/671170
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101)
G06F 30/20 (20200101) Original (OR) Class
G06F 2111/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784532 Rustomji et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) SOUTH 8 TECHNOLOGIES, INC. (San Diego, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) South 8 Technologies, Inc. (San Diego, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Cyrus Sam Rustomji (San Diego, California);  Yangyuchen Yang (La Jolla, California);  Daniel Davies (San Diego, California);  Jungwoo Lee (San Diego, California);  Ying Shirley Meng (San Diego, California)
ABSTRACT Chemical additives are disclosed to increase solubility of salts in liquefied gas electrolytes.
FILED Monday, October 28, 2019
APPL NO 16/666131
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/60 (20130101)
H01G 11/64 (20130101)
H01G 11/78 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101) Original (OR) Class
H01M 10/0567 (20130101)
H01M 10/0569 (20130101)
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784593 Sims, III
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William Herbert Sims, III (New Market, Alabama)
ABSTRACT A dual-band patch antenna includes a first patch antenna for operation at a first frequency and a second patch antenna for operation at a second frequency that is an integer multiple of the first frequency. A dielectric support is provided on which the first and second patch antennas are mounted. A nearest distance defined between the first and second patch antennas is a function of the second frequency and a dielectric constant of the dielectric support. The dielectric support has a feed point adapted to have a transmission line electrically coupled thereto. Electrically-conducting paths are coupled to the dielectric support for electrically coupling the feed point to the first and second patch antennas where at least one such electrically-conducting path has an insertion loss that is greater than 0 dB and less than or equal to 3 dB.
FILED Thursday, August 02, 2018
APPL NO 16/053422
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/523 (20130101)
H01Q 9/0414 (20130101)
H01Q 21/30 (20130101) Original (OR) Class
H01Q 21/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP32218 NeSmith
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) D. Scott NeSmith (Griffin, Georgia)
ABSTRACT The new variety ‘TH-931’ is provided. The new and distinct variety ripens around late May in south Georgia and early June in middle Georgia. The fruit of the new variety ‘TH-931’ are very large and firm. The new variety ‘TH-931’ exhibits high yields with an estimated chilling requirement of about 400 to 500 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
FILED Thursday, November 07, 2019
APPL NO 16/602612
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/368 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP32219 NeSmith
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc (Athens, Georgia)
INVENTOR(S) D. Scott NeSmith (Griffin, Georgia)
ABSTRACT The new variety ‘TH-1008’ is provided. The new and distinct variety flowers in early March in south Georgia, requiring frost protection for acceptable yields. The fruit of the new variety ‘TH-1008’ are ripen in early May in south Georgia and are very large, firm, and have good flavor. The new variety ‘TH-1008’ is compact with an estimated chilling requirement of about 200 to 300 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
FILED Thursday, November 07, 2019
APPL NO 16/602611
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/368 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10782421 Tosh et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Ronald Tosh (Frederick, Maryland);  Zeeshan Ahmed (Washington, District of Columbia);  Ryan P. Fitzgerald (Washington, District of Columbia);  Nikolai Klimov (Ellicott City, Maryland)
ABSTRACT A photonic calorimeter converts ionizing radiation dose to heat and includes: a radiation absorber, a temperature compensator disposed within the radiation absorber, a compensation waveguide, a compensation resonator, a compensation resonator, a thermal isolator on which the radiation absorber is disposed and that thermally isolates the radiation absorber from heat loss by thermal transfer due to physical contact by an object, and the temperature compensator changes the optical resonance of the compensation resonator in response to a change in temperature of the radiation absorber due to absorption of the ionizing radiation by the radiation absorber.
FILED Friday, February 15, 2019
APPL NO 16/276939
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/12 (20130101) Original (OR) Class
G01T 1/026 (20130101)
G01T 7/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/124 (20130101)
G02B 6/29323 (20130101)
G02B 6/29338 (20130101)
G02B 2006/12107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784848 Jariwala et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  Regent of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Deep M. Jariwala (Evanston, Illinois);  Vinod K. Sangwan (Syracuse, New York);  Weichao Xu (Minneapolis, Minnesota);  Hyungil Kim (Woodbury, Minnesota);  Tobin J. Marks (Evanston, Illinois);  Mark C. Hersam (Wilmette, Illinois)
ABSTRACT Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies.
FILED Tuesday, November 19, 2019
APPL NO 16/688714
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/283 (20130101)
H01L 27/286 (20130101)
H01L 29/78693 (20130101)
H01L 51/0003 (20130101)
H01L 51/0017 (20130101)
H01L 51/0048 (20130101)
H01L 51/105 (20130101)
H01L 51/0545 (20130101)
H01L 51/0562 (20130101)
H01L 2251/303 (20130101)

Pulse Technique
H03K 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10779612 Hansen et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Andrew H. Hansen (Minneapolis, Minnesota);  Sara R. Koehler (Minneapolis, Minnesota);  Charles J. Schultz (Minneapolis, Minnesota);  Eric A. Nickel (Minneapolis, Minnesota)
ABSTRACT A rocker shoe has a lower rocker surface extending across the plantar surface of the shoe sole from the heel and terminating short of the toe. A rocker shoe construction kit has a rigid or substantially rigid rocker piece having an upper surface for securing over a major portion of a lower plantar surface of the sole of a shoe upper and a lower surface of predetermined rocker shape, a cushioning layer for securing over the lower surface of the rocker piece, and a layer of tread material configured for securing over the lower surface of the cushioning layer and any exposed portion of the plantar surface of a shoe.
FILED Tuesday, May 14, 2019
APPL NO 16/411593
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Characteristic Features of Footwear; Parts of Footwear
A43B 3/0078 (20130101)
A43B 3/0094 (20130101)
A43B 3/246 (20130101)
A43B 7/32 (20130101)
A43B 13/12 (20130101)
A43B 13/16 (20130101)
A43B 13/32 (20130101)
A43B 13/143 (20130101)
A43B 13/145 (20130101) Original (OR) Class
A43B 13/188 (20130101)
A43B 13/189 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/12 (20130101)
B32B 2437/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10780147 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  U.S. Government Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Los Angeles, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Steven M. Dubinett (Los Angeles, California);  Sherven Sharma (Oakland, California);  Upendra K. Kar (Oakland, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
FILED Friday, February 03, 2017
APPL NO 15/424654
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 47/6921 (20170801)
A61K 48/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/521 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/96 (20130101)
C12N 9/1077 (20130101)
C12N 15/86 (20130101)

Enzymes
C12Y 204/0203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10780145 Overstreet et al.
FUNDED BY
U.S. State Government
State of Arizona
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona);  Banner Health (Phoenix, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  BANNER HEALTH (Phoenix, Arizona)
INVENTOR(S) Derek Overstreet (Chandler, Arizona);  Brent Vernon (Queen Creek, Arizona);  Ryan McLemore (Phoenix, Arizona);  Alex McLaren (Scottsdale, Arizona)
ABSTRACT A hydrogel (I), comprising a polymer backbone wherein an aqueous solution of the hydrogel comprises a first lower critical solution temperature, and wherein the hydrogel is configured to be converted in vivo into a modified hydrogel, and wherein an aqueous solution of the modified hydrogel comprises a second lower critical solution temperature, and wherein the second lower critical solution temperature is greater than the first lower critical solution temperature.
FILED Wednesday, December 13, 2017
APPL NO 15/840621
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0024 (20130101)
A61K 38/14 (20130101) Original (OR) Class
A61K 47/32 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/50 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 2300/404 (20130101)
A61L 2400/06 (20130101)
A61L 2430/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783787 Hourdos et al.
FUNDED BY
U.S. State Government
State of Minnesota
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) John Hourdos (Minneapolis, Minnesota);  Zhejun Liu (Minneapolis, Minnesota)
ABSTRACT A method includes using sensors to collect information about vehicles on a road and determining a plurality of crash probabilities based on the collected information. Each crash probability indicates a probability of a vehicular crash on the road at a respective point in time. The plurality of crash probabilities is averaged to form an average crash probability and the average crash probability is used to determine when to provide a message to a controller of a vehicle.
FILED Wednesday, May 30, 2018
APPL NO 15/993148
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Traffic Control Systems
G08G 1/0112 (20130101)
G08G 1/0116 (20130101)
G08G 1/0133 (20130101)
G08G 1/0141 (20130101)
G08G 1/164 (20130101) Original (OR) Class
G08G 1/096775 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 10783341 Stephen et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Victoria K. Stephen (Burke, Virginia);  Elke Reuning-Elliott (Rosslyn, Virginia)
ABSTRACT A multi-level distribution and tracking method is described. Processing equipment processes multi-level distribution items, the multi-level distribution items being associated with first, second, and third level entities. The multi-level distribution items include a computer readable code thereon. The processing equipment captures an image of the multi-level distribution item, reads a computer readable code associated with the first level entity, sender information for the second level entity, and destination address information for the third level entity. The distribution system delivers the item to the destination address for the third level entity. The processing equipment generates scan information based on the processing of the multi-level distribution item, and can send the tracking information to the first level entity.
FILED Thursday, December 26, 2019
APPL NO 16/727416
ART UNIT 2876 — Optics
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/10 (20130101)
B07C 3/14 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 5/025 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1413 (20130101)
G06K 7/1417 (20130101)
G06K 7/10861 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101)

Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus
G07B 2017/00475 (20130101)
G07B 2017/00588 (20130101)
G07B 2017/00596 (20130101)
G07B 2017/00709 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10783486 Irwin et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Donald Eugene Irwin (Fredericksburg, Virginia);  Gabriel Michael Yessin (Vienna, Virginia);  Joram Shenhar (Fairfax, Virginia);  Joel Locknauth Dewnandan (Bladensburg, Maryland);  Michael LeRoy Spears (Chantilly, Virginia);  William Albert Tartal (Baltimore, Maryland)
ABSTRACT Systems, devices and methods for storage, delivery, receipt, and/or other handling of an item in an electronically controllable storage receptacle are disclosed. The disclosure provides features for keyless access to the storage receptacle by use of user access information, such as a PIN or bar code. Further, features are disclosed for receiving and/or transmitting data related to the recipient and the item to facilitate the various handling actions of the item.
FILED Friday, August 31, 2018
APPL NO 16/119927
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6218 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0836 (20130101) Original (OR) Class
G06Q 10/0837 (20130101)
G06Q 2220/00 (20130101)

Coin-freed or Like Apparatus
G07F 5/18 (20130101)
G07F 17/12 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 10785250 Linder
FUNDED BY
Department of the Interior (DOI)
APPLICANT(S) Orbis Technologies, Inc. (Annapolis, Maryland)
ASSIGNEE(S) ORBIS TECHNOLOGIES, INC. (Annapolis, Maryland)
INVENTOR(S) Kojo Linder (Ellicott City, Maryland)
ABSTRACT Methods, systems and computer program products are provided to determine an individual's risk of being targeted by a cyberattack based on quantifying their online presence. In some embodiments, online information pertaining to an individual, accessible through the clear web (e.g., Internet) or the dark web, is identified and used to calculate a digital vulnerability (DV) score. The DV score is used to determine the susceptibility of an individual of being targeted for a cyberattack or cybercrime based upon their online presence, and may be computed based upon personally identifying information (PII) features present on clear web and deep/dark web resources.
FILED Friday, January 12, 2018
APPL NO 15/869209
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 16/9535 (20190101)
G06F 16/24578 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1433 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10783441 Riabov et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Anton V. Riabov (Ann Arbor, Michigan);  Shirin Sohrabi Araghi (White Plains, New York);  Octavian Udrea (Ossining, New York)
ABSTRACT In at least one embodiment, a method and a system for determining a set of plans that best match a set of preferences. The method may include receiving into a goal specification interface at least one goal to be accomplished by the set of plans; receiving into a preference engine a pattern that includes preferences; generating a planning problem by using the preference engine; generating a set of plans by at least one planner; and providing the set of plans for selection of one plan to deploy. In a further embodiment, the preferences may be an occurrence or non-occurrence of at least one component, an occurrence of one component over another component, an ordering between at least two components, an existence or non-existence of at least one tag in a final stream, an existence of one tag over another tag in the final stream.
FILED Tuesday, April 11, 2017
APPL NO 15/484727
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 7/523 (20130101)
G06F 16/22 (20190101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10781477 Trautman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ARATOME, LLC (Menlo Park, California)
ASSIGNEE(S) ARATOME, LLC (Menlo Park, California)
INVENTOR(S) Jay Trautman (Los Altos, California);  Gordon Wang (San Jose, California);  David Lenzi (Menlo Park, California)
ABSTRACT Disclosed herein are compositions, kits, methods, and systems for detecting a target molecule in a sample using a detection molecule.
FILED Wednesday, January 23, 2019
APPL NO 16/254926
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 16/20 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/44 (20130101)
C12Q 1/68 (20130101)
C12Q 1/6809 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6818 (20130101)
C12Q 1/6823 (20130101)
C12Q 1/6827 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 1/6888 (20130101)
C12Q 2521/501 (20130101)
C12Q 2537/119 (20130101)
C12Q 2563/107 (20130101)

Enzymes
C12Y 605/01001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/36 (20130101)
G01N 33/532 (20130101)
G01N 33/533 (20130101)
G01N 33/582 (20130101)
G01N 33/585 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10781351 Moore
FUNDED BY
APPLICANT(S) Louisiana Tech Research Corporation (Ruston, Louisiana)
ASSIGNEE(S) Louisiana Tech Research Corporation (Ruston, Louisiana)
INVENTOR(S) Arden L. Moore (Ruston, Louisiana)
ABSTRACT A porous hexagonal boron nitride (h-BN) material with thermally conductive properties, includes a network of interconnected struts and nodes. The porous h-BN material is formed by depositing h-BN onto a catalyst foam using chemical vapor deposition at atmospheric pressure. The catalyst foam with the h-BN layer deposited thereon is then encapsulated with an insulating material. After the insulating material layer is cured, the h-BN structure is cut on an edge and then wet-etched to at least partially remove the catalyst foam.
FILED Thursday, May 25, 2017
APPL NO 15/605631
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 21/0641 (20130101)
C01B 21/0648 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/16 (20130101)
C01P 2006/32 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/583 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 2003/385 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 5/14 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 428/12576 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10781707 Dyer et al.
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) David M. Dyer (Glastonbury, Connecticut);  Zachary J. Jeske (West Hartford, Connecticut);  Michael Ronan (Glastonbury, Connecticut);  Matthew E. Bintz (West Hartford, Connecticut);  John P. Tirone (Moodus, Connecticut);  Scott Gammons (Higganum, Connecticut);  Michael C. Firnhaber (East Hampton, Connecticut);  Mark E. Simonds (Cape Neddick, Maine)
ABSTRACT A vane stage includes a ringcase extending circumferentially about a center axis of the vane stage. The ringcase extends completely about the center axis to form a first ring. An inner shroud extends circumferentially about the center axis of the vane stage. The inner shroud extends completely about the center axis to form a second ring positioned radially within the ringcase relative the center axis. A plurality of stationary half vanes extend radially between the ringcase and the inner shroud, and are circumferentially spaced about the center axis. The plurality of stationary half vanes are integral with the ringcase and the inner shroud.
FILED Friday, September 14, 2018
APPL NO 16/131766
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/041 (20130101) Original (OR) Class
F01D 17/16 (20130101)
F01D 25/24 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/121 (20130101)
F05D 2240/122 (20130101)
F05D 2240/123 (20130101)
F05D 2240/124 (20130101)
F05D 2250/712 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782258 Graninger
FUNDED BY
APPLICANT(S) Aurelius L. Graninger (Sykesville, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Aurelius L. Graninger (Sykesville, Maryland)
ABSTRACT A system for measuring critical temperatures of superconducting components of a superconducting circuit housed in a cryogenic chamber with a controllable ambient temperature is described. The superconducting circuit can have a plurality of superconductor-resistor pairs connected in series. Each of the plurality of superconductor-resistor pairs can include a superconducting component and a resistor coupled in parallel with the superconducting component. The system can also include a resistance meter that measures a resistance of the superconducting circuit. The system further includes a controller that commands the cryogenic chamber to gradually sweep the ambient temperature. The controller can also record an instant ambient temperature as a critical temperature for a given superconducting component of a corresponding one of the plurality of superconductor-resistor pairs in response to detecting a change in a measured resistance across an input node and an output node of the superconducting circuit.
FILED Tuesday, September 04, 2018
APPL NO 16/120859
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/12 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/18 (20130101)
H01L 39/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10782480 Numata et al.
FUNDED BY
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Hidetoshi Numata (Kawasaki, Japan);  Masao Tokunari (Kawasaki, Japan)
ABSTRACT An optoelectronic coupling system includes an optoelectronic chip mounted on a substrate, having one or more optoelectronic components. A lower lens array is positioned over the optoelectronic chip and has a lower surface with a first portion at a first height to mount on the substrate and a second portion at a second height, higher than the first height, to accommodate a height of the optoelectronic chip. The lower lens array has an upper surface that comprises one or more lower lenses positioned over respective optoelectronic components of the one or more optoelectronic components. An upper lens array is positioned over the lower lens array and has one or more upper lenses positioned over respective lower lenses.
FILED Tuesday, January 08, 2019
APPL NO 16/242503
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/32 (20130101) Original (OR) Class
G02B 6/425 (20130101)
G02B 6/428 (20130101)
G02B 6/4206 (20130101)
G02B 6/4214 (20130101)
G02B 6/4244 (20130101)
G02B 6/4246 (20130101)
G02B 6/4249 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10784826 Creamer et al.
FUNDED BY
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Jersey)
INVENTOR(S) Carlton T. Creamer (Brookline, New Hampshire);  Christopher R. Bye (Bedford, New Hampshire);  Vali Touba (Bedford, New Hampshire);  Stephen J Creane (Arlington, Virginia)
ABSTRACT The present disclosure provide a device, system, and method for generating, in an electrical device, a 1 bit or a 0 bit that is received in a switching circuit powered by a battery. The device, system, and method generates, in the switching circuit, a negative bias voltage and a positive bias voltage. The device, system, and method transmits the negative bias voltage and the positive bias voltage to a power amplifier. The device, system, and method turns the power amplifier from an off-state to an on-state in response to receiving the negative bias voltage. The device, system, and method amplifies, with the power amplifier, a power signal moving through power amplifier when the amplifier is in the on-state.
FILED Wednesday, October 24, 2018
APPL NO 16/169092
ART UNIT 2843 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 1/0277 (20130101)
H03F 3/19 (20130101)
H03F 3/68 (20130101)
H03F 3/211 (20130101) Original (OR) Class
H03F 2200/451 (20130101)
H03F 2203/211 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 22, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200922.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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