FedInvent™ Patents
Patent Details for Tuesday, September 29, 2020
This page was updated on Monday, March 27, 2023 at 06:11 AM GMT
Department of Health and Human Services (HHS)
| US 10785968 | Flavell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland) |
| ASSIGNEE(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland) |
| INVENTOR(S) | Richard Flavell (Guilford, Connecticut); Till Strowig (Braunschweig, Germany); Markus G. Manz (Zollikon, Switzerland); Chiara Borsotti (Bronxville, New York); Madhav Dhodapkar (New Haven, Connecticut); Andrew J. Murphy (Croton-on-Hudson, New York); Sean Stevens (San Diego, California); George D. Yancopoulos (Yorktown Heights, New York) |
| ABSTRACT | Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804989 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/01 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Peptides C07K 14/524 (20130101) C07K 14/535 (20130101) C07K 14/5403 (20130101) C07K 14/5412 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786156 | Culver et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Joseph P. Culver (St. Louis, Missouri); Karla Bergonzi (St. Louis, Missouri); Adam Eggebrecht (St. Louis, Missouri); Silvina Ferradal (St. Louis, Missouri) |
| ABSTRACT | A system includes a wearable head apparatus and an electronic console. The head apparatus is configured to receive resultant light from the head of a subject. The electronic console includes a fiber array, a detector, and a computing device. The fiber array includes a plurality of fibers configured to transport resultant light received by the head apparatus. The detector includes a plurality of super-pixels each defined by a plurality of pixels of an array of pixels. Each super-pixel is associated with a fiber. Each super-pixel is configured to generate a plurality of detection signals in response to detected resultant light from its associated fiber. The computing device receives the detection signals from each of the plurality of super-pixels. The computing device generates a high density-diffuse optical tomography (HD-DOT) image signal of the brain activity of the subject based on the detection signals from the super-pixels. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 15/519350 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/0073 (20130101) Original (OR) Class A61B 5/726 (20130101) A61B 5/742 (20130101) A61B 5/4064 (20130101) A61B 5/4878 (20130101) A61B 5/6803 (20130101) A61B 5/7207 (20130101) A61B 2576/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786168 | Brown et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Boston, Massachusetts) |
| INVENTOR(S) | Emery N. Brown (Brookline, Massachusetts); Seong-Eun Kim (Cambridge, Massachusetts); Michael Behr (Cambridge, Massachusetts); Demba Ba (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing electrophysiological signals acquired from a subject are provided. In some aspects, a method includes receiving electrophysiological signals acquired from a subject using one or more sensors, and assembling a set of time-series data using the acquired electrophysiological signals. The method also includes analyzing the set of time-series data using a state-space multi-taper framework to generate spectral information describing the electrophysiological signals, and determining a brain state of the subject using the spectral information. The method further includes generating a report indicative of the determined brain state. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826182 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/048 (20130101) A61B 5/0402 (20130101) A61B 5/0482 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/0533 (20130101) A61B 5/725 (20130101) A61B 5/04017 (20130101) Original (OR) Class A61B 5/4812 (20130101) A61B 5/4821 (20130101) A61B 5/7257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786199 | Giuffrida et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph P Giuffrida (Hinckley, Ohio); Dustin A Heldman (Shaker Heights, Ohio); Thomas O Mera (Columbus, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Joseph P Giuffrida (Hinckley, Ohio); Dustin A Heldman (Shaker Heights, Ohio); Thomas O Mera (Columbus, Ohio) |
| ABSTRACT | The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/847970 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/1101 (20130101) A61B 5/4082 (20130101) A61B 5/4839 (20130101) Original (OR) Class A61B 5/6824 (20130101) A61B 5/6826 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36067 (20130101) A61N 1/36139 (20130101) A61N 1/37282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786200 | Giuffrida |
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| FUNDED BY |
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| APPLICANT(S) | Joseph Giuffrida (Hinckley, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Joseph Giuffrida (Hinckley, Ohio) |
| ABSTRACT | The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/847974 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0488 (20130101) A61B 5/742 (20130101) A61B 5/1101 (20130101) A61B 5/4082 (20130101) A61B 5/4839 (20130101) Original (OR) Class A61B 5/6826 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786201 | Linnes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jacqueline Callihan Linnes (West Lafayette, Indiana); Orlando Sanguinette Hoilett (West Lafayette, Indiana); Ashlyn Twibell (South Bend, Indiana); Hyowon Lee (West Lafayette, Indiana); Rohit Srivastava (Ballwin, Montana); Jason D Ummel (Greencastle, Indiana); Ryan Lindsey (Evansville, Indiana) |
| ABSTRACT | This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wrist watch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/159007 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0205 (20130101) A61B 5/681 (20130101) Original (OR) Class A61B 5/743 (20130101) A61B 5/0816 (20130101) A61B 5/1112 (20130101) A61B 5/02433 (20130101) A61B 5/4833 (20130101) A61B 5/7207 (20130101) A61B 5/7257 (20130101) A61B 5/14552 (20130101) A61B 2503/12 (20130101) A61B 2560/0214 (20130101) A61B 2560/0228 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786232 | Murray |
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| FUNDED BY |
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| APPLICANT(S) | Martha M. Murray (Sherborn, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Martha M. Murray (Sherborn, Massachusetts) |
| ABSTRACT | Methods and devices for the repair of a ruptured ligament using a scaffold device are provided. Aspects of the invention, may include a scaffold attached by a suture to an anchor. In aspects of the invention, the anchor may be secured to a bone near or at the repair site. |
| FILED | Tuesday, May 01, 2012 |
| APPL NO | 13/461269 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0401 (20130101) Original (OR) Class A61B 17/0469 (20130101) A61B 17/1146 (20130101) A61B 2017/00004 (20130101) A61B 2017/044 (20130101) A61B 2017/0414 (20130101) A61B 2017/0458 (20130101) A61B 2017/00893 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0811 (20130101) A61F 2002/0888 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/12 (20130101) A61L 27/22 (20130101) A61L 27/24 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 2430/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786261 | Maitland et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Duncan J. Maitland (College Station, Texas); Todd L. Landsman (San Jose, California); Jennifer N. Rodriguez (Fremont, California); Anthony J. Boyle (College Station, Texas); Alan C. Glowczwski (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/754330 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1215 (20130101) A61B 17/1219 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 2017/00526 (20130101) A61B 2017/00871 (20130101) A61B 2017/00898 (20130101) A61B 2017/12063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786446 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Minglin Ma (Ithaca, New York); Daniel G. Anderson (Framingham, Massachusetts); Robert S. Langer (Newton, Massachusetts); Omid Veiseh (Bellaire, Texas); Joshua Charles Doloff (Quincy, Massachusetts); Delai Chen (Woburn, Massachusetts); Christian J. Kastrup (Bowen Island, Canada); Arturo Jose Vegas (Belmont, Massachusetts) |
| ABSTRACT | Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/200334 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 9/4833 (20130101) A61K 9/4866 (20130101) A61K 9/5036 (20130101) A61K 9/5078 (20130101) A61K 9/5089 (20130101) A61K 35/39 (20130101) A61K 45/06 (20130101) A61K 2035/126 (20130101) A61K 2035/128 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786463 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jordan Jamieson Green (Nottingham, Maryland); Aleksander S. Popel (Lutherville, Maryland); Joel Chaim Sunshine (Pikesville, Maryland); Ron B. Shmueli (Baltimore, Maryland); Stephany Yi Tzeng (Baltimore, Maryland); Kristen Lynn Kozielski (Baltimore, Maryland) |
| ABSTRACT | Polymeric nanoparticles, microparticles, and gels for delivering cargo, e.g., a therapeutic agent, such as a peptide, to a target, e.g., a cell, and their use for treating diseases, including angiogenesis-dependent diseases, such as age-related macular degeneration and cancer, are disclosed. Methods for formulating, stabilizing, and administering single peptides or combinations of peptides via polymeric particle and gel delivery systems also are disclosed. |
| FILED | Monday, July 10, 2017 |
| APPL NO | 15/645337 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/5026 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 38/39 (20130101) A61K 47/34 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 15/111 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786466 | Shulman et al. |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Gerald I. Shulman (East Haven, Connecticut); Rachel Jamison Perry (New Haven, Connecticut) |
| ABSTRACT | The present invention includes a low dose and sustained release formulation of 2,4-dinitrophenol (DNP). The compositions of the invention are useful for preventing or treating a disease or disorder, such as non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, insulin resistance and/or diabetes, in a subject in need thereof. |
| FILED | Friday, August 29, 2014 |
| APPL NO | 14/911322 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/501 (20130101) A61K 9/5026 (20130101) A61K 9/5042 (20130101) A61K 9/5047 (20130101) A61K 31/06 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786471 | Muir et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Muir (Cambridge, Massachusetts); Matthew Vander Heiden (Cambridge, Massachusetts); Laura Danai (Brighton, Massachusetts); Dan Yi Gui (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods and related compositions for enhancing cancer therapy and in particular glutaminase inhibitor therapy. The methods involve methods for identifying patients susceptible to glutaminase inhibitor therapy as well as sensitizing patients to glutaminase inhibitor therapy. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/890220 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/69 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 31/225 (20130101) A61K 31/255 (20130101) A61K 31/255 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/501 (20130101) A61K 31/501 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/7105 (20130101) A61K 38/1709 (20130101) A61K 45/00 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2333/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786519 | Badley |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Andrew D. Badley (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials for treating HIV infections. For example, methods and materials for using one or more proteosome inhibitors in combination with one or more other agents to treat HIV infections are provided. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 15/552636 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 31/69 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/4402 (20130101) A61K 31/4402 (20130101) A61K 31/5365 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 39/21 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786527 | Rotello et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Vincent M. Rotello (Amherst, Massachusetts); Ying Jiang (Sunderland, Massachusetts); Rui Tang (Amherst, Massachusetts) |
| ABSTRACT | The invention provides nanoparticle-stabilized nanocapsules, and methods of their preparation and use in delivery of therapeutics, such as nucleic acids. Various embodiments disclosed relate to a nanoparticle-stabilized nanocapsule. Various embodiments disclosed relate to nanoparticle-stabilized nanocapsules for nucleic acid delivery into cells. Various embodiments provide methods of using the nanocapsule for in vivo delivery of the nucleic acid materials. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/073689 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 47/6875 (20170801) A61K 47/6901 (20170801) A61K 47/6925 (20170801) A61K 47/6929 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10786532 — Method of providing cellular therapy using modified natural killer cells or T lymphocytes
| US 10786532 | Malarkannan |
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| FUNDED BY |
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| APPLICANT(S) | Versiti Blood Research Institute Foundation, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | VERSITI BLOOD RESEARCH INSTITUTE FOUNDATION, INC. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Subramaniam Malarkannan (Menomonee Falls, Wisconsin) |
| ABSTRACT | A method of decreasing cytokine production and release is disclosed. In one embodiment, the method comprises the step of providing cytotoxic cells to a subject wherein the cells are preferably natural killer cells or T lymphocytes and are genetically modified to express a chimeric antigen receptor comprising a first element that is an extracellular antigen receptor and a second intracellular element that is a signaling moiety comprising altered ADAP-dependent or Fyn-dependent signaling such that downstream signaling causing cytokine release is decreased. Specific modifications of CD137 and NKG2D cytoplasmic tails are described. Additionally, methods to develop and screen drug compounds capable of compromising the binding between ADAP and Fyn and disrupting the downstream release of cytokines are described. |
| FILED | Monday, September 30, 2013 |
| APPL NO | 14/433082 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 35/545 (20130101) A61K 38/17 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786541 | Lang et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Bradley T. Lang (Cleveland, Ohio); Jerry Silver (Cleveland, Ohio); Ryan Gardner (Portland, Oregon); Beth Habecker (Portland, Oregon) |
| ABSTRACT | A method of treating heart disease and/or injury in a subject includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTPσ. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279621 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) Original (OR) Class Peptides C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786542 | Laskin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey D. Laskin (Piscataway, New Jersey); Ron Udasin (East Brunswick, New Jersey); Lauren Aleksunes (Bridgewater, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey D. Laskin (Piscataway, New Jersey); Ron Udasin (East Brunswick, New Jersey); Lauren Aleksunes (Bridgewater, New Jersey) |
| ABSTRACT | Methods and pharmaceutical compositions for inhibiting or decreasing transport of a drug by a transporter of multidrug resistance-associated protein comprising a compound of Formula (V): wherein R1 and R2 are small peptides or modified peptides, are provided. The methods and compositions are useful in enhancing efficacy of drugs such as anti-inflammatory agents, neurological agents, thyroid agents, ocular agents, cancer chemotherapeutics, antibiotics, antimicrobials, antivirals and protease inhibitors to treat human immunodeficiency virus. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/516811 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/03 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 38/063 (20130101) Peptides C07K 5/0215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786543 | Paolocci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Nazareno Paolocci (Baltimore, Maryland); Ning Feng (Baltimore, Maryland); Carlo G. Tocchetti (Baltimore, Maryland); Cyrus Takahashi (Baltimore, Maryland); Bruce Carter (Nashville, Tennessee) |
| ABSTRACT | The present invention provides 75 kD transmembrane neurotrophin receptor (p75NTR) antagonists and their use in prevention and treatment of loss of function, and adverse remodeling, in cardiac tissues subject to acute or chronic hemodynamic stress. Uses of the antagonists with or without additional cardiotropic agents for improving contractility and for treatment of congestive heart failure are also provided. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/762238 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) A61K 49/0004 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5061 (20130101) G01N 33/5082 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786545 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yibin Kang (Princeton, New Jersey); Yongna Xing (Middleton, Wisconsin); Liling Wan (Princeton, New Jersey); Feng Guo (Sunnyvale, California) |
| ABSTRACT | The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406837 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/82 (20130101) C07K 14/4748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786559 | Talaat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Adel M. Talaat (Madison, Wisconsin); Sarah K. Ward (Madison, Wisconsin); Bassam Abomoelak (Orlando, Florida) |
| ABSTRACT | Methods of preparing mutants of Mycobacterium tuberculosis with one or more disrupted genes are presented, where the disrupted genes include ctpV, rv0990c, rv0971c, and/or rv0348. Compositions containing mutants with attenuated virulence and pathogenesis, which are capable of stimulation of an immune response against tuberculosis, are described. Compositions and methods relating to immunogenic compositions, which include an attenuated M. tb strain in which the M. tb genome includes a disruption of at least one of the ctpV gene, the rv0990c gene, the rv0971c gene, and the rv0348 gene, are also provided. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914172 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/522 (20130101) Peptides C07K 14/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/74 (20130101) C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786570 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Jeffrey Friedman (New York, New York); Sarah Stanley (New York, New York) |
| ABSTRACT | The present invention provides methods and compositions for the remote control of cell function based on the use of radiofrequency waves to excite nanoparticles targeted to specific cell types. The nanoparticles may be applied to the target cell extracellularly and/or expressed intracellularly. The cell type of interest expresses a temperature sensitive channel wherein excitation of the nanoparticles results in a localized temperature increase that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. Accordingly, the invention provides a generic approach for treatment of any disease associated with a protein deficiency. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049102 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/167 (20130101) A61K 9/1611 (20130101) A61K 33/26 (20130101) A61K 38/1709 (20130101) A61K 38/1767 (20130101) A61K 41/0028 (20130101) A61K 41/0052 (20130101) Original (OR) Class A61K 47/6929 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/406 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 16/18 (20130101) C07K 2317/22 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/30 (20130101) C07K 2319/035 (20130101) C07K 2319/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786573 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Xinyan Cui (Wexford, Pennsylvania); Xiliang Luo (Qingdao, China PRC); Cassandra Weaver (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xinyan Cui (Wexford, Pennsylvania); Xiliang Luo (Qingdao, China PRC); Cassandra Weaver (Pittsburgh, Pennsylvania) |
| ABSTRACT | A composition includes a composite material including at least one conducting polymer doped with graphene oxide and at least one agent immobilized at least one of (i) on graphene oxide extending from the surface of the composite material or (ii) within the composite material. |
| FILED | Friday, October 04, 2013 |
| APPL NO | 14/433389 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/7007 (20130101) A61K 31/573 (20130101) A61K 38/39 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) Original (OR) Class A61K 47/34 (20130101) A61K 47/52 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786582 | Meade et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Thomas J. Meade (Willmette, Illinois); Matthew W. Rotz (Chicago, Illinois); Robert J. Holbrook (Evanston, Illinois) |
| ABSTRACT | Provided herein are compositions Gd(III)-dithiolane gold nanoparticle conjugates and methods of use thereof. In particular, compositions and method find use in in vivo imaging (e.g., magnetic resonance imaging (MRI)), for example, of pancreatic tissue. |
| FILED | Friday, July 05, 2019 |
| APPL NO | 16/504021 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/085 (20130101) Original (OR) Class A61K 49/1878 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786625 | Giuffrida et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph P Giuffrida (Hinckley, Ohio); Dustin A Heldman (Shaker Heights, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Joseph P Giuffrida (Hinckley, Ohio); Dustin A Heldman (Shaker Heights, Ohio) |
| ABSTRACT | The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician. |
| FILED | Friday, February 28, 2014 |
| APPL NO | 14/193286 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/14244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786640 | Avitsian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); PARKER HANNIFIN CORPORATION (Cleveland, Ohio) |
| ASSIGNEE(S) | PARKER-HANNIFIN CORPORATION (Cleveland, Ohio); THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Rafi Avitsian (Solon, Ohio); Andrew Zura (Beachwood, Ohio); Gino Banco (Lyndhurst, Ohio); Sean Lee (Cleveland, Ohio) |
| ABSTRACT | One aspect of the present disclosure relates to a reversible airway device. The reversible airway device (10) can include: a supra-glottic airway support (12) comprising a multi-lumen tubular guide (14) and an optional sealing member (16); an endotracheal tube (26); and at least one seal (42). The multi-lumen tubular guide has a distal end portion (18), a proximal end portion (22), a first passageway (20) extending between the distal and proximal end portions, and a second passageway (24) that is non-concentric with the first passageway and also extends between the distal and proximal end portions. The at least one seal is disposed within the first passageway, the second passageway, or both, so as to occlude the flow of a gas through the first passageway and/or the second passageway. The endotracheal tube can be inserted into the first or second passageway and can traverse the seal. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/573536 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0409 (20140204) Original (OR) Class A61M 16/0434 (20130101) A61M 16/0459 (20140204) A61M 16/0475 (20140204) A61M 16/0477 (20140204) A61M 16/0486 (20140204) A61M 16/0488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786673 | Nandra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Mandheerej Nandra (Pasadena, California); Yu-Chong Tai (Pasadena, California) |
| ABSTRACT | Neuromodulation systems are described. An example neuromodulation system includes a controller wirelessly communicatively coupled to a host computer, a signal generator communicatively coupled to the controller, and a plurality of electrodes communicatively coupled to the signal generator. The controller, in conjunction with the signal generator and the at least one electrode are configured to deliver a stimulation to a mammal based on an instruction received from the host computer. The stimulation is configured to induce voluntary movement or restore function in the mammal. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 15/713456 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/0488 (20130101) A61B 5/4836 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0553 (20130101) A61N 1/0558 (20130101) A61N 1/3787 (20130101) A61N 1/36003 (20130101) A61N 1/36067 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/36185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786676 | Molnar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Gregory Frederick Molnar (St. Paul, Minnesota); Luke Johnson (St. Paul, Minnesota); David Escobar Sanabria (St. Paul, Minnesota); Edward Mark Bello, II (St. Paul, Minnesota); Jerrold L. Vitek (St. Paul, Minnesota); Matthew D. Johnson (St. Paul, Minnesota) |
| ABSTRACT | Described here is a deep brain stimulation (“DBS”) approach that targets several relevant nodes within brain circuitry, while monitoring multiple symptoms for efficacy. This approach to multi-symptom monitoring and stimulation therapy may be used as an extra stimulation setting in extant DBS devices, particularly those equipped for both stimulation and sensing. The therapeutic efficacy of DBS devices is extended by optimizing them for multiple symptoms (such as sleep disturbance in addition to movement disorders), thus increasing quality of life for patients. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788563 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0478 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/4064 (20130101) A61B 5/4082 (20130101) A61B 5/4806 (20130101) A61B 5/4812 (20130101) A61B 5/4836 (20130101) A61B 5/6868 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/0534 (20130101) A61N 1/3787 (20130101) A61N 1/36067 (20130101) A61N 1/36078 (20130101) A61N 1/36139 (20130101) Original (OR) Class A61N 1/37258 (20130101) A61N 1/37264 (20130101) A61N 2/006 (20130101) A61N 7/00 (20130101) A61N 2007/0026 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786685 | Moore-Ede et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CIRCADIAN ZIRCLIGHT INC. (Stoneham, Massachusetts) |
| ASSIGNEE(S) | CIRCADIAN ZIRCLIGHT INC. (Stoneham, Massachusetts) |
| INVENTOR(S) | Martin Christopher Moore-Ede (Wellesley, Massachusetts); Rebecca Mary Chacko (Brookline, Massachusetts); Anneke Marlies Heitmann (Arlington, Massachusetts); Robert Frederic Casper (Toronto, Canada); Robert Frank Karlicek, Jr. (Clifton, New York); Doros Platika (Pittsburgh, Pennsylvania); Udo Trutschel (Tabarz, Germany) |
| ABSTRACT | Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 15/669846 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) A61M 2021/0005 (20130101) A61M 2021/0044 (20130101) A61M 2021/0083 (20130101) A61M 2205/50 (20130101) A61M 2205/3368 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0618 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/065 (20130101) A61N 2005/0629 (20130101) A61N 2005/0636 (20130101) A61N 2005/0651 (20130101) A61N 2005/0652 (20130101) A61N 2005/0653 (20130101) A61N 2005/0654 (20130101) A61N 2005/0658 (20130101) A61N 2005/0663 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/592 (20130101) C09K 11/621 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/20 (20160801) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/08 (20130101) F21V 14/08 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2105/00 (20130101) F21Y 2113/00 (20130101) F21Y 2115/10 (20160801) F21Y 2115/15 (20160801) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/20 (20200101) H05B 47/16 (20200101) H05B 47/155 (20200101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 20/42 (20130101) Y02B 20/181 (20130101) Y02B 20/341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787410 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Douglas Robinson (Towson, Maryland); Alexandra Surcel (Baltimore, Maryland); Win Pin Ng (Berkeley, California); Caren L. Freel Meyers (Towson, Maryland) |
| ABSTRACT | Described are methods of treating or preventing a disease in a subject treatable by modulating cell mechanics. The method includes administering to a subject having or at risk for such a disease a pharmaceutical composition comprising an agent selected from the group comprising a salt, solvate, or stereoisomer of compound (VIII) or its derivatives or a mixture of their constituents, where the compound has the formula: |
| FILED | Friday, April 06, 2018 |
| APPL NO | 15/946849 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/15 (20130101) A61K 31/15 (20130101) A61K 31/27 (20130101) A61K 31/27 (20130101) A61K 31/136 (20130101) A61K 31/136 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 49/825 (20130101) Original (OR) Class C07C 251/80 (20130101) C07C 271/58 (20130101) C07C 275/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/44 (20130101) G01N 2333/4712 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787419 | Kunos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Massachusetts) |
| INVENTOR(S) | George Kunos (Bethesda, Maryland); Malliga Iyer (Germantown, Maryland); Resat Cinar (Bethesda, Maryland); Kenner C. Rice (Bethesda, Maryland) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a CB1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/674333 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/06 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 409/12 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787421 | Wagner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Carl Wagner (Glendale, Arizona); Peter Jurutka (Scottsdale, Arizona); Pamela Marshall (Peoria, Arizona) |
| ABSTRACT | The invention provides compounds formula (I) and salts thereof: wherein R1-R4 have any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal. |
| FILED | Tuesday, January 15, 2019 |
| APPL NO | 16/248110 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 229/60 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 213/79 (20130101) C07D 213/80 (20130101) C07D 237/24 (20130101) C07D 239/42 (20130101) Original (OR) Class C07D 241/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787424 | Arora et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Brooke Bullock Lao (Leesville, South Carolina); Richard Bonneau (New York, New York); Kevin Drew (Austin, Texas) |
| ABSTRACT | The present invention relates to oxopiperazines that mimic helix αB of the C-terminal transactivation domain of HIF1α. Also disclosed are pharmaceutical compositions containing these oxopiperazines and methods of using these oxopiperazines (e.g., to reduce gene transcription, treat or prevent disorders mediated by interaction of HIF1a with CREB-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, and decrease cell survival and/or proliferation). |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 15/312875 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/80 (20130101) C07C 29/80 (20130101) C07C 29/88 (20130101) C07C 29/88 (20130101) C07C 31/04 (20130101) C07C 31/225 (20130101) Heterocyclic Compounds C07D 241/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787433 | Hodgetts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); OHIO STATE UNIVERSITY (Columbus, Ohio) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); OHIO STATE UNIVERSITY (Columbus, Ohio) |
| INVENTOR(S) | Kevin Hodgetts (Framingham, Massachusetts); Chien-Liang Glenn Lin (Columbus, Ohio) |
| ABSTRACT | Pyradizine derivatives that activity the excitatory amino acid transporter 2 (EAAT2) of the formula: and methods of use thereof for treating or preventing diseases, disorders, and conditions with glutamate toxicity. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 16/070393 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 29/00 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 237/20 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 413/14 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787436 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, neuroblastoma, lung cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7)), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/130975 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 417/04 (20130101) C07D 471/04 (20130101) C07D 513/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787439 | Golden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas); The Regents of the University of Michigan (Ann Arbor, Michigan); Wayne State University (Detroit, Michigan); Sanford-Burnham Medical Research Institute (La Jolla, California) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (La Jolla, California); WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| INVENTOR(S) | Jennifer E. Golden (Olathe, Kansas); Jeffrey Aube (Lawrence, Kansas); Daniel P. Flaherty (Overland Park, Kansas); Andrew M. Fribley (Brighton, Michigan); Randal J. Kaufman (San Diego, California); Thomas D. Y. Chung (Carlsbad, California); Anthony B. Pinkerton (San Diego, California); Michael Pablo Hedrick (Carlsbad, California) |
| ABSTRACT | N-substituted sulfonylphenyl-5-nitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the Unfolded Protein Response are provides as is their use in the treatment of diseases such as diabetes, Alzheimer's, Parkinson's, hemophilia, lysosomal storage diseases and cancer. |
| FILED | Wednesday, August 09, 2017 |
| APPL NO | 15/672574 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/4525 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 303/36 (20130101) Heterocyclic Compounds C07D 307/71 (20130101) C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787453 | Petrukhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Albany, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Albany, New York); Ping Chen (Albany, New York); Michael Conlon (Albany, New York); Lei Zhu (Albany, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Albany, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Albany, New York); Ping Chen (Albany, New York); Michael Conlon (Albany, New York); Lei Zhu (Albany, New York) |
| ABSTRACT | The present invention provides compounds comprising variously substituted octahydropyrrolopyrroles, their synthesis, methods of making, methods of using, compositions and formulations thereof. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/950528 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/55 (20130101) A61K 31/407 (20130101) A61K 31/498 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/4162 (20130101) A61K 31/4192 (20130101) A61K 31/4196 (20130101) A61K 31/4353 (20130101) A61K 31/5355 (20130101) A61K 31/5365 (20130101) Heterocyclic Compounds C07D 209/52 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 498/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787461 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); David Waller (Somerville, Massachusetts); Hwan Guen Choi (Seoul, South Korea); Jinhua Wang (Boston, Massachusetts); Xianming Deng (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), LRKK2, EphA2, polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK1, ULK2, PLK4, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and the use of such compounds in the treatment of various diseases, disorders or conditions. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570490 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/18 (20130101) C07D 487/04 (20130101) C07D 487/12 (20130101) C07D 487/14 (20130101) C07D 487/16 (20130101) C07D 487/18 (20130101) C07D 495/14 (20130101) C07D 498/04 (20130101) C07D 498/18 (20130101) C07D 513/04 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787490 | Bhandari et al. |
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| FUNDED BY |
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| APPLICANT(S) | Protagonist Therapeutics, Inc. (Newark, California) |
| ASSIGNEE(S) | Protaganist Therapeutics, Inc. (Newark, California) |
| INVENTOR(S) | Ashok Bhandari (Pleasanton, California); Gregory Bourne (Jindalee, Australia); Xiaoli Cheng (Mountain View, California); Brian Troy Frederick (Ben Lomand, California); Jie Zhang (Salisbury, Australia); Dinesh V. Patel (Fremont, California); David Liu (Palo Alto, California) |
| ABSTRACT | Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases, are described. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/745371 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787499 | Hackel et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Benjamin Hackel (Minneapolis, Minnesota); Carston R. Wagner (Minneapolis, Minnesota); Lawrence A. Stern (Minneapolis, Minnesota); Clifford Csizmar (Minneapolis, Minnesota) |
| ABSTRACT | Certain embodiments of the invention provide epithelial cell adhesion molecule (EpCAM) binding polypeptides, as well as conjugates and CSANs comprising such polypeptides. Additionally, certain embodiments of the invention also provide methods of using such polypeptides and compounds for molecular imaging and molecularly targeted therapies. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895834 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6435 (20170801) A61K 49/0056 (20130101) A61K 51/08 (20130101) A61K 51/088 (20130101) Peptides C07K 14/78 (20130101) Original (OR) Class C07K 2319/735 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787503 | Crowe, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Scott A. Smith (White Bluff, Tennessee); Terence Dermody (Brentwood, Tennessee); Laurie Silva (Nashville, Tennessee) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/566283 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/181 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/383 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787513 | Pardoll et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); St. Jude's Children's Research Hospital Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); St. Jude's Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Drew M. Pardoll (Brookeville, Maryland); Ching-Tai Huang (Taipei, Taiwan); Jonathan Powell (Baltimore, Maryland); Charles Drake (Baltimore, Maryland); Dario A. Vignali (Pittsburgh, Pennsylvania); Creg J. Workman (Memphis, Tennessee) |
| ABSTRACT | Anti-CD223 antibodies overcome immune suppression in cancer patients. The anti-CD223 antibodies may be generated in an animal by injection of fragments of CD223. Antibodies may be monoclonal antibodies or single chain antibodies or humanized antibodies. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/973806 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0276 (20130101) A01K 2267/0381 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 2035/122 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/5156 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/70503 (20130101) C07K 16/18 (20130101) C07K 16/42 (20130101) C07K 16/2803 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787523 | Rotello et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Vincent M. Rotello (Amherst, Massachusetts); Rubul Mout (Amherst, Massachusetts) |
| ABSTRACT | Various embodiments disclosed relate to a nanoparticle-protein complex for intracellular protein delivery. In various embodiments, the present invention provides a nanoparticle-protein complex including a nanoparticle including an amine-containing ligand. The nanoparticle-protein complex also includes a protein comprising a carboxylic acid-containing tag. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/547404 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6923 (20170801) Peptides C07K 17/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 9/1241 (20130101) C12N 9/6467 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 304/21078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787641 | Yoon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Young-sup Yoon (Atlanta, Georgia); Hyun-Jai Cho (Seoul, South Korea) |
| ABSTRACT | The present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/334541 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 5/0087 (20130101) C12N 5/0634 (20130101) Original (OR) Class C12N 5/0647 (20130101) C12N 5/0692 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787646 | Estes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary K. Estes (Houston, Texas); David Graham (Houston, Texas); Robert Legare Atmar (Houston, Texas); Sue Ellen Crawford (Conroe, Texas); Khalil Ettayebi (Pearland, Texas); Kosuke Murakami (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure concern systems, methods, and/or compositions for cultivation of mammalian viruses, including at least human noroviruses and sapoviruses within the Caliciviridae family of viruses. The ex vivo culture systems include intestinal enteroids in combination with bile or a functionally active fraction or component thereof. In specific embodiments, the culture system is utilized to test inactivation compounds for therapeutic or environmental efficacy and to test contaminated comestibles and/or environmental entities for determination of the presence of infectious virus. Furthermore, antiviral compositions may be tested using systems of the disclosure, including drugs, small molecule inhibitors, and biologies such as neutralizing monoclonal antibodies. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/763695 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0679 (20130101) C12N 7/00 (20130101) C12N 7/02 (20130101) Original (OR) Class C12N 2770/16051 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787661 | St. Onge et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Robert P. St. Onge (Palo Alto, California); Ulrich Schlecht (Palo Alto, California); Sasha F. Levy (Stony Brook, New York); Ronald W. Davis (Palo Alto, California); Joseph Horecka (Fremont, California) |
| ABSTRACT | A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 14/928928 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1031 (20130101) C12N 15/1034 (20130101) C12N 15/1034 (20130101) C12N 15/1037 (20130101) Original (OR) Class C12N 15/1058 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787664 | Natarajan et al. |
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| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Rama Natarajan (Duarte, California); Mitsuo Kato (Duarte, California) |
| ABSTRACT | The present disclosure relates to isolated compounds including a nucleic acid sequence capable of hybridizing to an RNA sequence 10 to 270 nucleobases downstream of the transcription start site of a mammalian microRNA-379 transcript; method of treating diabetic nephropathy in a subject with the compounds; and method of inhibiting expression of a mammalian microRNA-379 megacluster with the compounds. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/163816 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787684 | Byrne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Susan M. Byrne (Brookline, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of simultaneously excising large nucleic acid sequences from a target nucleic acid and inserting large foreign nucleic sequences into the target nucleic acid sequence using DNA binding protein nucleases are described. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/319693 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) C12N 15/907 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787703 | Storici et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Francesca Storici (Atlanta, Georgia); Jay Hesselberth (Atlanta, Georgia); Kyung Duk Koh (Atlanta, Georgia) |
| ABSTRACT | Genomic DNA contains embedded ribonucleotides (rNMPs) that are incorporated during DNA replication and repair, or formed during DNA damage. The modifications have been linked to genome instability and disease, but no method currently exists to profile their locations genome-wide. rNMP incorporation has been extensively studied in recent years; however, locating sites of rNMP incorporation in genomic DNA has not yet been possible. Disclosed herein is a unique method for mapping rNMPs in genomic DNA that exploits the unique ligation mechanism of Arabidopsis thaliana tRNA ligase (AtRNL), normally involved in tRNA maturation. As disclosed herein AtRNL captures 2′,3′-cyclic phosphate or 2′-phosphate termini of DNA derived from alkaline cleavage of a DNA oligonucleotide (oligo) at an embedded rNMP, ligating the 2′-phosphate end to the 5′-phosphate terminus of the same DNA molecule and producing a ssDNA circle containing an embedded rNMP. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 15/402217 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) Original (OR) Class C12Q 1/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787704 | Gunderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Illumina, Inc. (San Diego, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | ILLUMINA, INC. (San Diego, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kevin L Gunderson (Encinitas, California); Jingwei Bai (San Diego, California); Cheng-Yao Chen (Eugene, Oregon); Jeffrey G Mandell (San Diego, California); Sergio Peisajovich (San Diego, California); Philip G Collins (Oakland, California); Gregory A Weiss (Oakland, California); Boyan Boyanov (San Diego, California) |
| ABSTRACT | The present disclosure provides a method for sequencing nucleic acids. The method can include polymerase catalyzed incorporation of nucleotides into a nascent nucleic acid strand against a nucleic acid template, wherein the polymerase is attached to a charge sensor that detects nucleotide incorporation events. One or more non-natural nucleotide types that each produce a unique signatures at the charge sensor can be used to uniquely identify different nucleotides in the template nucleic acid. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/572741 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/543 (20130101) C12Q 2565/607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787705 | Esfandyarpour et al. |
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| FUNDED BY |
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| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
| ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/896572 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787709 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Barbara Murphy (Pelham Manor, New York); Weijia Zhang (Cresskill, New Jersey) |
| ABSTRACT | Disclosed herein is a method for diagnosing a renal allograft recipient's risk for developing fibrosis of the allograft and allograft loss. The method includes determining the expression levels of certain microRNAs, which have been determined to be predictive of an allograft recipient's risk. Also disclosed herein is a method of treating a renal allograft recipient to inhibit fibrosis of the allograft and allograft loss, as well as kits for use in the methods disclosed herein. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/424014 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/343 (20130101) A61K 31/436 (20130101) A61K 31/573 (20130101) A61K 31/4412 (20130101) A61K 31/5377 (20130101) A61K 38/13 (20130101) A61K 38/18 (20130101) A61K 38/1774 (20130101) A61K 38/1875 (20130101) A61K 38/2221 (20130101) Peptides C07K 14/70521 (20130101) C07K 2319/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) G01N 2800/245 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787710 | LaBaer et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Joshua LaBaer (Chandler, Arizona); Kristin Gillis (Mesa, Arizona); Garrick Wallstrom (Mesa, Arizona); Jin Park (Phoenix, Arizona); Vel Murugan (Chandler, Arizona); Mitch Magee (Chandler, Arizona) |
| ABSTRACT | Disclosed herein are compositions and methods for accurately estimating the absorbed dose of radiation indicated by a subject based on the expression pattern of a panel of radiation-modulated (RM) genes at various time points following exposure of the subject to ionizing radiation. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/532138 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787712 | Sjoblom et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Tobias Sjoblom (Uppsala, Sweden); Sian Jones (Baltimore, Maryland); D. Williams Parsons (Bellaire, Texas); Laura D. Wood (Baltimore, Maryland); Jimmy Cheng-Ho Lin (Baltimore, Maryland); Thomas Barber (Nobelsville, Tennessee); Diana Mandelker (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Victor E. Velculescu (Dayton, Maryland) |
| ABSTRACT | Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of ˜90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention and monitoring. |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 16/824052 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787713 | Samuels et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Yardena Samuels (Potomac, Maryland); Victor E. Velculescu (Dayton, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the PI3K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the PI3K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853230 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788413 | Tucker-Schwartz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jason Michael Tucker-Schwartz (Cambridge, Massachusetts); Shivang R. Dave (Boston, Massachusetts) |
| ABSTRACT | Method for distinguishing between red blood cells and white blood cells. The method includes obliquely illuminating the blood sample with light from at least two rotational angles and analyzing light side scattered from cells in the sample to provide accurate discrimination of white blood cell types based on the anisotropy of red blood cell side scatter as compared to more isotropic white blood cell side scatter. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/399172 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 15/1436 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 33/492 (20130101) G01N 33/4915 (20130101) G01N 2015/008 (20130101) G01N 2015/0073 (20130101) G01N 2015/1006 (20130101) G01N 2015/1488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788453 | Clemmer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees Of Indiana University (Indianapolis, Indiana) |
| ASSIGNEE(S) | The Trustees Of Indiana University (Indianapolis, Indiana) |
| INVENTOR(S) | David E. Clemmer (Bloomington, Indiana); Michael A. Ewing (Zurich, Switzerland) |
| ABSTRACT | An ion mobility spectrometer includes a drift tube responsive to application of at least a first voltage to establish a first electric field therein configured to cause ions within the drift tube to move along and about the drift tube while separating from one another as a function of ion mobility, and a transition region coupled to opposed ends of the first drift tube such that the drift tube and the transition region together define a closed path. The transition region is responsive to application of at least a second voltage to cause the ions to move along and about the closed path, to application of at least a third voltage to selectively pass ions into the drift tube and to application of at least a fourth voltage to selectively pass ions out of the drift tube. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357366 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/26 (20130101) H01J 49/46 (20130101) H01J 49/443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788486 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Peng Zhang (Lawrence, Kansas); Yong Zeng (Olathe, Kansas); Mei He (Manhattan, Kansas) |
| ABSTRACT | A capture device for capturing a biological substance can include: a substrate; a graphene-oxide layer on the substrate; at least one polydopamine polymer coupled with the graphene-oxide; and at least one targeting receptor coupled to the polydopamine(s), wherein the targeting receptor is capable of targeting/binding with a target biological substance. The graphene-oxide may be covalently coupled with the substrate and polydopamine, and the polydopamine may be covalently coupled with the targeting receptor. The targeting receptor can be an antibody or fragment thereof. The target biological substance can be an exosome. The substrate can be a particle (e.g., magnetic, such as magnetically responsive) or a surface in a microfluidic channel. The surface can be a top surface of a post, the post having a Y-shaped cross-sectional profile. In one aspect, the substrate is a particle. The capture device can include the target biological substance bound to the targeting receptor. |
| FILED | Monday, October 09, 2017 |
| APPL NO | 15/728155 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0631 (20130101) B01L 2200/0647 (20130101) B01L 2300/0636 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/54326 (20130101) G01N 33/54353 (20130101) G01N 33/54393 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788492 | Shenk et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Shenk (Princeton, New Jersey); Todd M. Greco (Langhorne, Pennsylvania); Ileana M. Cristea (Princeton, New Jersey); Rommel A. Mathias (Plainsboro, New Jersey); Adam Oberstein (Princeton, New Jersey) |
| ABSTRACT | The present application demonstrates that sirtuin 4 (SIRT4) acts as a cellular lipoamidase that negatively regulates pyruvate dehydrogenase complex (PDHC) activity through hydrolysis of its lipoamide cofactors. |
| FILED | Thursday, January 15, 2015 |
| APPL NO | 15/106932 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/90212 (20130101) G01N 2333/91057 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788496 | Garraway et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Levi A. Garraway (Newton, Massachusetts); Caroline Emery (Kansas City, Missouri); Nikhil Wagle (Brookline, Massachusetts) |
| ABSTRACT | Nucleic acids and proteins having a mutant MEK sequence, and methods concerning identification of patients having resistance to treatment with anti-cancer agents, specifically inhibitors of RAF or MEK are provided. Methods of treatment and for optimizing treatment for patients having a mutation in a MEK1 sequence are also provided. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/844236 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/12002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) Original (OR) Class G01N 2333/91205 (20130101) G01N 2500/10 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788499 | Gelb et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Michael H. Gelb (Seattle, Washington); Frantisek Turecek (Seattle, Washington) |
| ABSTRACT | The present disclosure provides assays for lysosomal enzymes, specifically palmitoyl protein thioesterase 1 (PPT1) and tripeptidyl peptidase 1 (TPP1), using, for example, tandem mass spectrometry. The assays involve the detection of enzymatic products obtained through the action of the lysosomal enzymes on new enzyme substrates, and can be used for quantitative enzyme activity measurements. The assays for the enzymes utilize a minimum steps for sample work up and can be run in a simplex format or in a duplex format for the detection of neuronal ceroid lipofuscinoses, or in a multiplex format with other mass spectrometry-based assays for screening of neuronal ceroid lipofuscinoses and other lysosomal storage disorders. |
| FILED | Wednesday, July 13, 2016 |
| APPL NO | 15/744736 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 5/00 (20130101) C07K 5/08 (20130101) C07K 5/0806 (20130101) C07K 5/0812 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/44 (20130101) C12Q 2334/20 (20130101) C12Q 2337/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2333/916 (20130101) G01N 2800/04 (20130101) G01N 2800/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788500 | Lee |
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| FUNDED BY |
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| APPLICANT(S) | Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Richard T. Lee (Weston, Massachusetts) |
| ABSTRACT | This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/849135 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00112 (20180801) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/7155 (20130101) G01N 2800/32 (20130101) G01N 2800/52 (20130101) G01N 2800/324 (20130101) G01N 2800/325 (20130101) G01N 2800/2871 (20130101) Technologies for Adaptation to Climate Change Y02A 90/24 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788555 | Alsop et al. |
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| FUNDED BY |
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| APPLICANT(S) | BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | David Alsop (Newton, Massachusetts); Gopal Varma (Boston, Massachusetts) |
| ABSTRACT | A magnetic resonance imaging (MRI) system is provided that is controlled by a computer. The computer is programmed to control a plurality of gradient coils and radio frequency (RF) system of the MRI system to perform at least one pulse sequence that includes applying RF energy at least at two frequencies to manipulate exchangeable magnetization from protons in a subject. The computer is also programmed to control the plurality of gradient coils and RF system to acquire imaging data including magnetization transfer information from the exchangeable magnetization from protons in the subject in response to the pulse sequence. The computer is further programmed to, using frequency information associated with the imaging data, generate a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298041 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4041 (20130101) A61B 5/7278 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4828 (20130101) G01R 33/5605 (20130101) Original (OR) Class G01R 33/5659 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10789713 | Frank et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method and system for registration of a multi-dimensional image include defining an input image and a reference image in the same fixed Cartesian grid, then mapping locations within the reference image and the input image to phase space using a Hamiltonian function to define a symplectomorphic map, where the map is embedded in an energy shell. The mapping step is iterated until a sequence of energy shells is created. The energy shells are used generate curvilinear mapping grid which is then applied to the first image to generate a registered output image data. The data may be preconditioned to account for nearest neighbor coupling and/or to equalize the dimensionality of the images. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 16/071418 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0016 (20130101) Original (OR) Class G06T 7/37 (20170101) G06T 11/008 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790040 | Califano et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Andrea Califano (New York, New York); Mariano Javier Alvarez (Cortlandt Manor, New York) |
| ABSTRACT | Methods for determining regulon enrichment in gene expression signatures are disclosed herein. An example method can include obtaining a set of transcriptional targets of a regulon. The method can include obtaining a gene expression signature by comparing a gene expression profile of a test sample to gene expression profiles of a plurality of samples representing control phenotypes. The method can include calculating a regulon enrichment score for each regulon in the gene expression signature. The method can including determining whether a number of control samples in the control phenotypes is above a predetermined threshold to support evaluation of statistical significance using permutation analysis. The method can include, in response to determining that the number of control samples is above the predetermined threshold, calculating a significance value by comparing each regulon enrichment score to a null model. |
| FILED | Friday, August 26, 2016 |
| APPL NO | 15/248975 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 20/00 (20190201) Original (OR) Class G16B 25/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791318 | Shechtman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yoav Shechtman (Santa Clara, California); William E. Moerner (Stanford, California); Lucien Weiss (Los Angeles, California) |
| ABSTRACT | Among other aspects, various embodiments include encoding wavelength-based characteristics, in addition to three-dimensional positions, of a plurality of objects of a plurality of different wavelengths directly in an image of the objects. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/439491 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0056 (20130101) G02B 21/0064 (20130101) G02B 26/06 (20130101) Pictorial Communication, e.g Television H04N 13/161 (20180501) H04N 13/214 (20180501) H04N 13/218 (20180501) Original (OR) Class H04N 13/271 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10786568 | Limberis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Janssen Biotech, Inc. (Horsham, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Janssen Biotech, Inc. (Horsham, Pennsylvania) |
| INVENTOR(S) | Maria P. Limberis (Philadelphia, Pennsylvania); Anna P. Tretiakova (Woburn, Massachusetts); James M. Wilson (Philadelphia, Pennsylvania); Michael Naso (Swarthmore, Pennsylvania); Joost Kolkman (Maarn, Netherlands); Robert Friesen (Wassenaar, Netherlands); Qiang Wang (Philadelphia, Pennsylvania) |
| ABSTRACT | A non-replicating recombinant adeno-associated associated virus (rAAV) having an AAV capsid having packaged therein a vector genome which comprises AAV inverted terminal repeat sequences and at least one nucleic acid sequence encoding four different immunoglobulin regions (a), (b), (c) and (d) is provided. The rAAV-expressed immunoglobulins are useful for providing passive immunization against influenza A and influenza B. Also described herein are compositions containing the rAAV. Methods of vaccinating patients against influenza are provided. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906887 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 2039/505 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 7/06 (20130101) C12N 2750/14121 (20130101) C12N 2750/14143 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786683 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nitto Denko Corporation (Osaka, Japan); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | Nitto Denko Corporation (Osaka, Japan); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Sazzadur Rahman Khan (San Diego, California); Sheng Li (Vista, California); Amane Mochizuki (Osaka, Japan); Xingjia Wu (Germantown, Maryland); Juanita Josephine Anders (Potomac, Maryland) |
| ABSTRACT | Methods and devices related to wound healing using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring System 1, Ring System 2, Ring System 3, Ring System 4 or Ring System 5. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015923 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0616 (20130101) Original (OR) Class A61N 5/0624 (20130101) A61N 2005/063 (20130101) A61N 2005/0627 (20130101) A61N 2005/0645 (20130101) A61N 2005/0653 (20130101) A61N 2005/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786693 | Opperman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony Opperman (Lakewood, Ohio); Frederick J Lisy (Euclid, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Anthony Opperman (Lakewood, Ohio); Frederick J Lisy (Euclid, Ohio) |
| ABSTRACT | The present invention is a wearable device for comprehensive bio-monitoring of physiologic metrics to determine metabolic, pulmonary and cardiac function and oxygen saturation measurements from breathing mask apparatuses. The device non-invasively monitors the physiologic profile of the subject, and is capable of detecting physiologic changes, predicting onset of symptoms, and alerting the wearer or another person or system. In some embodiments, the device comprises both a wearable sensor suite and a portable gas composition and flow analysis system. In preferred embodiments, it comprises a miniaturized non-invasive sensor suite for detecting physiologic changes to detect dangerous breathing or other health conditions. The system utilizes advanced fast-response sensors with improved efficiency and lifespan, and provides rapid analysis for substantially real-time monitoring of the subject's present condition to predict, mitigate and/or prevent the onset of dangerous conditions. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 14/847592 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/097 (20130101) A61B 5/0873 (20130101) A61B 5/7275 (20130101) A61B 2503/12 (20130101) A61B 2560/0223 (20130101) A61B 2560/0252 (20130101) Devices, Apparatus or Methods for Life-saving A62B 7/14 (20130101) A62B 9/006 (20130101) Original (OR) Class A62B 18/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786805 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Stephen C. Jensen (Chicago, Illinois); Emily A. Weiss (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions comprising cadmium sulfide quantum dot photocatalysts and methods and systems utilizing as much (e.g., for the reduction of a nitrobenzene to an aniline). |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/074169 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/123 (20130101) B01J 19/127 (20130101) B01J 27/04 (20130101) Original (OR) Class B01J 35/002 (20130101) B01J 35/004 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Acyclic or Carbocyclic Compounds C07C 211/46 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787231 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Cong Wang (Pasadena, California); David Jeon (Pasadena, California); Morgane Grivel (Pasadena, California); Francisco Pereira (Rome, Italy); Morteza Gharib (Altadena, California) |
| ABSTRACT | Systems, methods and apparatuses are provided for the reduction of hydrodynamic frictional drag. These systems, methods and apparatuses can include a vessel surface having an external layer and a plurality of dimples, wherein the external layer comprises a hydrophilic material, and wherein each of the dimples includes an inner surface having a superhydrophobic coating. The dimples can be configured to maintain an air-water interface as one or more fluids flow over the vessel surface. In some embodiments, a pressure reservoir can be coupled with the dimples, and can include an acoustic speaker to vibrate the air-water interface. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 15/663595 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 1/38 (20130101) Original (OR) Class B63B 2001/387 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1618 (20130101) C09D 5/1637 (20130101) C09D 5/1681 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/005 (20130101) F15D 1/007 (20130101) F15D 1/12 (20130101) F15D 1/065 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 70/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787503 | Crowe, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Scott A. Smith (White Bluff, Tennessee); Terence Dermody (Brentwood, Tennessee); Laurie Silva (Nashville, Tennessee) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/566283 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/181 (20130101) Technologies for Adaptation to Climate Change Y02A 50/51 (20180101) Y02A 50/383 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787658 | Heggeness |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Michael H. Heggeness (Wichita, Kansas) |
| ABSTRACT | The disclosure relates to nerve derived adult pluripotent stem cells characterized by expression of Oct4, Sox2, c-Myc, and Klf4, methods for obtaining them, and their use. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375006 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 5/0623 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2501/155 (20130101) C12N 2506/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787660 | Santiago et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Juan G. Santiago (Stanford, California); Lewis A. Marshall (Pleasanton, California); Anita Rogacs (Los Altos, California) |
| ABSTRACT | Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/192034 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 57/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 2200/10 (20130101) B01L 2200/027 (20130101) B01L 2200/0621 (20130101) B01L 2200/0631 (20130101) B01L 2200/0684 (20130101) B01L 2300/12 (20130101) B01L 2300/165 (20130101) B01L 2300/0838 (20130101) B01L 2300/0858 (20130101) B01L 2300/0867 (20130101) B01L 2400/086 (20130101) B01L 2400/088 (20130101) B01L 2400/0406 (20130101) B01L 2400/0421 (20130101) B01L 2400/0688 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787695 | Puleo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Christopher Michael Puleo (Niskayuna, New York); Christine Lynne Surrette (Niskayuna, New York); Erik Leeming Kvam (Albany, New York); Steven Yuehin Go (Schenectady, New York); Feng Chen (Schenectady, New York); John Richard Nelson (Clifton Park, New York); Craig Patrick Galligan (Schenectady, New York); Radislav Alexandrovich Potyrailo (Niskayuna, New York); Gregory Andrew Grossmann (Halfmoon, New York) |
| ABSTRACT | A system includes a bacteria culture array that includes a plurality of chambers each configured to receive a portion of a sample that includes bacteria. Each individual chamber of the plurality of chambers includes a chamber opening configured to permit access of the portion of the sample to the individual chamber. The system also includes one or more sensors configured to collect data from the individual chamber. The sensors are configured to contact the sample. Additionally, the system includes a monitoring and analysis system that includes a processor configured to receive the data from the one or more sensors at a first time and a second time, compare the data received at the second time to the data received at the first time, and identify a portion of the plurality of chambers of the bacteria culture array based on the comparing. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 15/611586 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/00 (20130101) C12M 41/46 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6452 (20130101) G01N 33/4836 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787744 | George et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Steven McClellan George (Boulder, Colorado); Nicholas Ray Johnson (Louisville, Colorado); Jaime Willadean Dumont (Racine, Wisconsin); Amy Elizabeth Marquardt (Chicago, Illinois); Younghee Lee (Boulder, Colorado); David Richard Zywotko (Boulder, Colorado); Aziz Abdulagatov (Boulder, Colorado) |
| ABSTRACT | The invention includes a method of promoting atomic layer etching (ALE) of a surface. In certain embodiments, the method comprises sequential reactions with a metal precursor and a halogen-containing gas. In other embodiments, the etching rate is increased by removing residual species bound to and/or adsorbed onto the surface. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049258 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 4/00 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/465 (20130101) H01L 21/30621 (20130101) H01L 21/31116 (20130101) H01L 21/31122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787912 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Corey D. Anderson (East Hartford, Connecticut); Brandon W. Spangler (Vernon, Connecticut) |
| ABSTRACT | Baffles and airfoils for installation within gas turbine engines are provided. The baffles include a baffle side wall extending between a first end and a second end and a baffle divider within the baffle side wall, wherein the baffle divider and the baffle side wall define a first cavity and a second cavity. The first cavity is located at a first side at the first end and the second cavity is located at a second side at the first end and the baffle divider includes a spiral portion such that the first cavity is transitioned toward the second side and the second cavity is transitioned toward the first side. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962074 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 5/188 (20130101) Original (OR) Class F01D 9/065 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2240/126 (20130101) F05D 2250/15 (20130101) F05D 2250/24 (20130101) F05D 2250/25 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787996 | Kupratis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Daniel Bernard Kupratis (Wallingford, Connecticut); Francis R. Moon (Granby, Connecticut) |
| ABSTRACT | In accordance with one aspect of the disclosure, a stream diverter for a gas turbine engine is disclosed. The stream diverter may include a first air duct, a second air duct, a third air duct, and a door operatively associated with the second and third air ducts of the gas turbine engine. The door may have at least an open position allowing air from the second air duct to flow into the third air duct and a closed position preventing air from flowing between the ducts. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383900 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/13 (20130101) F02C 3/145 (20130101) F02C 9/18 (20130101) Jet-propulsion Plants F02K 1/80 (20130101) F02K 1/805 (20130101) F02K 3/06 (20130101) F02K 3/075 (20130101) Original (OR) Class F02K 3/077 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2210/40 (20130101) F05D 2250/311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788148 | Di Carlo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Tony Di Carlo (Long Beach, California); Brian T. Vaniman (Fountain Valley, California); John P. Leuer (Newport Beach, California) |
| ABSTRACT | A conduit (100) for transporting a fluid comprises a first collar (102), a second collar (103), a bellows (108), and a sensor (116). The bellows (108) comprises a central axis (180), a first corrugated outboard ply (114), a corrugated inboard ply (110), interposed between the first corrugated outboard ply (114) and the central axis (180), an interstitial space (126), interposed between the corrugated inboard ply (110) and the first corrugated outboard ply (114), and a second corrugated outboard ply (112) within the interstitial space (126). The corrugated inboard ply (110), the first corrugated outboard ply (114), and a weld-through ring (150) are welded to the first collar (102) and the second collar (102). The second corrugated outboard ply (112) is not hermetically coupled to the first collar (102) or the second collar (103). The sensor (116) is communicatively coupled with the interstitial space (126). |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/228089 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 5/022 (20130101) Original (OR) Class F16L 27/111 (20130101) F16L 2201/30 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788284 | Kathe |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Picatinny Arsenal, Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Eric Kathe (Ballston Lake, New York) |
| ABSTRACT | A counter momentum generator is employed on a weapon system to manage horizontal recoil momentum of the weapon system. The counter momentum generator generates a counter momentum which that is not parallel to the recoil momentum. A horizontal component of the counter momentum negates a portion of the horizontal recoil momentum. A vertical component of the counter momentum combines with the vertical recoil momentum to aid in compression between the base of the weapon system and the ground. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407541 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/28 (20130101) F41A 25/02 (20130101) Original (OR) Class Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788347 | Byrd |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Larry W. Byrd (Huber Heights, Ohio) |
| ABSTRACT | An estimate of interfacial areas between the liquid and gas, liquid and wall, and gas and wall in two phase flow is determined using a standard 2D sensor in a fashion to infer 3D information about the liquid/vapor profile when the sensor length is much longer than the diameter. Cross-sectional flow areas for the gas and liquid are also estimated as a function of the axial dimension of the sensor, and the centroid of the mass in the sensor element can also be estimated. An electric capacitance tomography (ECT) system creates tomograms of the flow inside a sensor, and estimates of 3D physical area information are produced from the tomograms. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 15/653622 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/64 (20130101) G01F 1/74 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/226 (20130101) G01N 27/228 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 11/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788360 | Figueiredo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Truventic, LLC (Orlando, Florida) |
| ASSIGNEE(S) | Truventic, LLC (Orlando, Florida) |
| INVENTOR(S) | Pedro N. Figueiredo (Longwood, Florida) |
| ABSTRACT | An infrared scene generator can generate a second infrared scene representative of a first infrared scene by emitting a beam of electromagnetic radiation onto a plurality of prism-coupled electrically conductive elements that modulate a portion of the beam incident thereon with surface plasmon polaritons based on parameters of the first infrared scene to yield a modulated beam that produces the second infrared scene. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262166 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/08 (20130101) Original (OR) Class G01J 1/44 (20130101) G01J 1/0477 (20130101) G01J 2001/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788462 | Troy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | James J. Troy (Issaquah, Washington); Daniel J. Wright (Mercer Island, Washington); Scott W. Lea (Renton, Washington); Gary Ernest Georgeson (Tacoma, Washington) |
| ABSTRACT | A dual function non-destructive inspection apparatus comprises a frame structure, a thermographic inspection system, a displacement system, and an ultrasonic inspection system. The frame structure has a channel, a first end, and a second end. The channel extends through the frame structure from the first end to the second end. The thermographic inspection system is associated with the first end of the frame structure. The displacement system is connected to the second end of the frame structure. The ultrasonic inspection system is connected to the displacement system such that the displacement system moves the ultrasonic inspection system relative to the channel of the frame structure. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/024347 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/72 (20130101) G01N 29/04 (20130101) G01N 29/265 (20130101) Original (OR) Class G01N 29/4454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788485 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Shinsuke Ishihara (Cambridge, Massachusetts) |
| ABSTRACT | A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer. |
| FILED | Wednesday, March 08, 2017 |
| APPL NO | 15/453217 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/78 (20130101) G01N 21/6428 (20130101) G01N 33/54386 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788555 | Alsop et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | David Alsop (Newton, Massachusetts); Gopal Varma (Boston, Massachusetts) |
| ABSTRACT | A magnetic resonance imaging (MRI) system is provided that is controlled by a computer. The computer is programmed to control a plurality of gradient coils and radio frequency (RF) system of the MRI system to perform at least one pulse sequence that includes applying RF energy at least at two frequencies to manipulate exchangeable magnetization from protons in a subject. The computer is also programmed to control the plurality of gradient coils and RF system to acquire imaging data including magnetization transfer information from the exchangeable magnetization from protons in the subject in response to the pulse sequence. The computer is further programmed to, using frequency information associated with the imaging data, generate a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298041 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4041 (20130101) A61B 5/7278 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4828 (20130101) G01R 33/5605 (20130101) Original (OR) Class G01R 33/5659 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788575 | Diapis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Jackeline D Diapis (North Kingstown, Rhode Island); Thomas A Frank (Richmond, Rhode Island); Lynn T Antonelli (Cranston, Rhode Island); Stephen C Butler (Portsmouth, Rhode Island) |
| ABSTRACT | Extendable air-based line arrays of directional projectors are provided with the arrays affixed and parallel to a ship hull. An anchor and a vibration isolator are affixed to the hull and the arrays in which the anchor and isolator separate the arrays from the hull. Each of hydraulically-actuated arms rotatably connect at a cam to an arm stop affixed to the anchor. A sound vibration dampener is positioned between the arm stops. The arms are capable of extending the directional projectors to an activation position with the projectors forming narrow beams into the water to become sonar waves that reflect from a target. The reflections from the target are received with a hydrophone on the ship. |
| FILED | Thursday, January 16, 2020 |
| APPL NO | 16/744281 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/521 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10789055 | Baskaran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Muthu Manikandan Baskaran (Old Tappan, New Jersey); Benoit J. Meister (New York, New York); Benoit Pradelle (Brooklyn, New York) |
| ABSTRACT | A system for compiling programs for execution thereof using a hierarchical processing system having two or more levels of memory hierarchy can perform memory-level-specific optimizations, without exceeding a specified maximum compilation time. To this end, the compiler system employs a polyhedral model and limits the dimensions of a polyhedral program representation that is processed by the compiler at each level using a focalization operator that temporarily reduces one or more dimensions of the polyhedral representation. Semantic correctness is provided via a defocalization operator that can restore all polyhedral dimensions that had been temporarily removed. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/285810 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) G06F 8/452 (20130101) G06F 8/4436 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10789194 | Dennison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Larry R. Dennison (Mendon, Massachusetts); Mark Hummel (Franklin, Massachusetts); Glenn Dearth (Groton, Massachusetts) |
| ABSTRACT | Systems and techniques for synchronizing transactions between processing devices on an interconnection network are provided. Upon receiving a stream of posted transactions followed by a flush transaction from a source processing device connected to the interconnection network, the flush transaction is trapped before it enters the interconnecting network. Subsequently, based on monitoring for responses received from a destination processing device for transactions corresponding to the posted transactions, a flush response is generated and returned to the source processing device. The described techniques enable efficient synchronizing posted writes, posted atomics and the like over complex interconnection fabrics such that a first GPU can write data to a second GPU so that a third GPU can safely consume the data written to the second GPU. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/364565 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3877 (20130101) G06F 12/0891 (20130101) G06F 13/4022 (20130101) Original (OR) Class G06F 2213/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10789755 | Amer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Mohamed R. Amer (Brooklyn, New York); Timothy J. Meo (Kendall Park, New Jersey); Aswin Nadamuni Raghavan (Princeton, New Jersey); Alex C. Tozzo (Philadelphia, Pennsylvania); Amir Tamrakar (Princeton, New Jersey); David A. Salter (Basking Ridge, Pennsylvania); Kyung-Yoon Kim (North York, Canada) |
| ABSTRACT | This disclosure describes techniques that include generating, based on a description of a scene, a movie or animation that represents at least one possible version of a story corresponding to the description of the scene. This disclosure also describes techniques for training a machine learning model to generate predefined data structures from textual information, visual information, and/or other information about a story, an event, a scene, or a sequence of events or scenes within a story. This disclosure also describes techniques for using GANs to generate, from input, an animation of motion (e.g., an animation or a video clip). This disclosure also describes techniques for implementing an explainable artificial intelligence system that may provide end users with information (e.g., through a user interface) that enables an understanding of at least some of the decisions made by the AI system. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230945 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/345 (20190101) G06F 16/738 (20190101) G06F 16/9024 (20190101) G06F 40/205 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00335 (20130101) G06K 9/00342 (20130101) G06K 9/00718 (20130101) G06K 9/00744 (20130101) G06K 9/6215 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 3/088 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 13/40 (20130101) G06T 13/80 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790157 | Oehrlein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Gottlieb S. Oehrlein (Clarksville, Maryland); Kang-Yi Lin (Greenbelt, Maryland); Chen Li (College Park, Maryland) |
| ABSTRACT | Provided is a method of selectively etching a substrate including at least one cycle of: depositing a chemical precursor on a surface of the substrate, the substrate including a first portion and a second portion, to selectively form a chemical precursor layer on a surface of the first portion of the substrate without forming or substantially without forming the chemical precursor layer on a surface of the second portion of the substrate, wherein the first portion of the substrate and the second portion of the substrate are of different composition; exposing the chemical precursor layer on the surface of the first portion of the substrate and the surface of the second portion of the substrate to a plasma environment subjected to a bias power; and selectively and in a self-limited fashion removing at least a part of the second portion of the substrate, and repeating the cycle until the second portion of the substrate is substantially or completely removed. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/512896 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0212 (20130101) H01L 21/02274 (20130101) H01L 21/31116 (20130101) H01L 21/31122 (20130101) H01L 21/31144 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790325 | Arbabi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Amir Arbabi (Pasadena, California); Seunghoon Han (Suwon-si, South Korea); Andrei Faraon (Pasadena, California); Hyeonsoo Park (Suwon-si, South Korea) |
| ABSTRACT | An image sensor includes a substrate, thin lenses disposed on a first surface of the substrate and configured to concentrate lights incident on the first surface, and light-sensing cells disposed on a second surface of the substrate, the second surface facing the first surface, and the light-sensing cells being configured to sense lights passing through the thin lenses, and generate electrical signals based on the sensed lights. A first thin lens and second thin lens of the thin lenses are configured to concentrate a first light and a second light, respectively, of the incident lights onto the light-sensing cells, the first light having a different wavelength than the second light. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/597491 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 35/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14605 (20130101) H01L 27/14621 (20130101) H01L 27/14627 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/2257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790631 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Zenghu Chang (Orlando, Florida); Xiaoming Ren (Orlando, Florida); Yanchun Yin (Orlando, Florida); Lam Mach (Orlando, Florida) |
| ABSTRACT | The present invention demonstrates a technique for achieving milli-joule level and higher energy, broad bandwidth laser pulses centered around 2.4 micrometer with a kilohertz and other repetition rate. The key to such technique is to start with a broadband micro-joule level seed laser at around 2.4 micrometer, which could be generated through difference frequency generation, four-wave mixing process and other methods. This micro-joule level seed laser could then be amplified to above one milli-joule through chirped pulse amplification in a Cr2+:ZnSe or Cr2+:ZnS crystal pumped by a commercially available Ho:YAG or other appropriate suitable lasers. Due to the high seed energy, fewer gain passes are needed to achieve a milli-joule level output thus significantly simplifies laser architectures. Furthermore, gain narrowing effect in a typical chirped pulse amplifier is also mitigated and thus enable a broadband output. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/032808 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) Original (OR) Class H01S 3/0092 (20130101) H01S 3/115 (20130101) H01S 3/161 (20130101) H01S 3/0606 (20130101) H01S 3/1623 (20130101) H01S 3/1625 (20130101) H01S 3/1628 (20130101) H01S 3/1636 (20130101) H01S 3/1643 (20130101) H01S 3/2308 (20130101) H01S 3/2316 (20130101) H01S 3/2325 (20130101) H01S 3/2375 (20130101) H01S 3/094076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790633 | Digonnet et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michel J. Digonnet (Stanford, California); Jennifer Knall (Stanford, California) |
| ABSTRACT | Fiber-based gain elements, such as fiber lasers, fiber amplifiers, and the like, that have higher power and better frequency stability than can be achieved in the prior art are presented. Embodiments include a fiber-based gain element having a first portion in which anti-Stokes fluorescence (ASF) reduces its temperature below that of an ambient environment and a second portion whose temperature is not reduced below that of the ambient environment, which are thermally coupled so heat can flow from the second portion into the first portion, thereby reducing the average temperature of the gain element. In some embodiments, a core configured to provide optical gain is thermally coupled with a first cladding configured to exhibit ASF cooling via an intervening cladding layer that acts to confine a first pump signal to the core. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/541015 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/06733 (20130101) H01S 3/06754 (20130101) H01S 3/094007 (20130101) H01S 3/094053 (20130101) Original (OR) Class Control of Amplification H03G 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790909 | Suni |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Paul J. Suni (Berthoud, Colorado) |
| ABSTRACT | A coherent optical system includes an optical transmit (Tx) path, a coherent optical receive (Rx) path, and a multi-channel optical path coupled to the optical Tx path and the coherent optical Rx path. The multi-channel optical path includes a number of parallel-connected channels and a formatting optics block having an optical beam directed to a target. Each channel includes an optical amplifier, and the optical Tx path, the coherent Rx path, and the multi-channel optical path are realized as a photonic integrated circuit (PIC). |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450878 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/40 (20130101) Original (OR) Class H04B 10/61 (20130101) H04B 10/503 (20130101) Multiplex Communication H04J 14/002 (20130101) H04J 14/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790911 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Yifei Li (Dartmouth, Massachusetts) |
| ABSTRACT | A Sagnac loop coherent phase modulated RF photonic link employing an ACP-OPLL linear phase demodulator was presented. This structure demonstrated stable signal transmission over a 1-km long coherent RF photonic link. |
| FILED | Wednesday, April 10, 2019 |
| APPL NO | 16/380452 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/035 (20130101) G02F 2202/20 (20130101) Transmission H04B 10/616 (20130101) Original (OR) Class H04B 10/25891 (20200501) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10786468 | Jabbarzadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Ehsan Jabbarzadeh (Columbia, South Carolina); Wesley F. Taylor (Cayce, South Carolina); Sara Eslambolchimoghada (Columbia, South Carolina) |
| ABSTRACT | A deacetylnemorone abietane diterpenoid is utilized in the prevention of growth and development of pathogenic cells, e.g., cancer cells. The deacetylnemorone can have the following structure: or a tautomer there of in which R1, R2, and R3 are independently selected from —H, C1-10 alkyl, C1-10 alkoxy, C1-10 alkenyl, C1-10 alkenoxy, —OH, —OAc, —CHO, -Ph, —OC6H5, —OC6H4OH, —COC6H5, —OCONH2, —OCONHCH3, —OCOC6H4NH2, —NH2, or ═O. The deacetylnemorone shows efficacy in treatment and prevention of a wide range of cancer types as well as other neoplastic diseases as a chemo-preventative, a primary or secondary cytotoxic agent, a sensitizer for other therapies, or one component of a combinatorial treatment. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/004550 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) Original (OR) Class A61K 31/7072 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786573 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Xinyan Cui (Wexford, Pennsylvania); Xiliang Luo (Qingdao, China PRC); Cassandra Weaver (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xinyan Cui (Wexford, Pennsylvania); Xiliang Luo (Qingdao, China PRC); Cassandra Weaver (Pittsburgh, Pennsylvania) |
| ABSTRACT | A composition includes a composite material including at least one conducting polymer doped with graphene oxide and at least one agent immobilized at least one of (i) on graphene oxide extending from the surface of the composite material or (ii) within the composite material. |
| FILED | Friday, October 04, 2013 |
| APPL NO | 14/433389 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/7007 (20130101) A61K 31/573 (20130101) A61K 38/39 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) Original (OR) Class A61K 47/34 (20130101) A61K 47/52 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786874 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Chunlei Guo (Rochester, New York); Anatoliy Y. Vorobyev (St. Catharines, Canada) |
| ABSTRACT | Embodiments of the present invention are generally directed to materials processing methods using femtosecond duration laser pulses, and to the altered materials obtained by such methods. The resulting nanostructured (with or without macro- and micro-structuring) materials have a variety of applications, including, for example, aesthetic applications for jewelry or ornamentation; biomedical applications related to biocompatibility; catalysis applications; and modification of, for example, the optical and hydrophilic properties of materials including selective coloring. |
| FILED | Tuesday, December 20, 2016 |
| APPL NO | 15/384398 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0006 (20130101) B23K 26/352 (20151001) B23K 26/355 (20180801) Original (OR) Class B23K 26/361 (20151001) B23K 26/362 (20130101) B23K 26/0624 (20151001) B23K 2103/05 (20180801) B23K 2103/08 (20180801) B23K 2103/10 (20180801) B23K 2103/12 (20180801) B23K 2103/14 (20180801) B23K 2103/16 (20180801) B23K 2103/42 (20180801) B23K 2103/50 (20180801) B23K 2103/52 (20180801) B23K 2103/54 (20180801) B23K 2103/56 (20180801) Producing Decorative Effects; Mosaics; Tarsia Work; Paperhanging B44C 1/228 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/09 (20130101) C21D 8/0294 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 3/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12201 (20150115) Y10T 428/12993 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787259 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Haijie Zhang (Fort Collins, Colorado); Jianguo Zhao (Fort Collins, Colorado); Jiefeng Sun (Fort Collins, Colorado) |
| ABSTRACT | A bistable gripper for an aerial vehicle may include a base, a first finger, a second finger, a switching pad, a first elastic connector, and a second elastic connector. The base may include a first beam and a second beam. The first finger may be pivotably attached to the first beam at a first joint, and the second finger may be pivotably attached to the second beam at a second joint. The switching pad may be configured for moving relative to the base. The first elastic connector may be attached to the switching pad and the first finger, and the second elastic connector may be attached to the switching pad and the second finger. The bistable gripper may be configured for switching between a closed stable state and an open stable state. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 16/678457 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/027 (20130101) B64C 2201/128 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787373 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A method of water treatment includes flowing water that includes nitrogen and phosphorus compounds through a sorption media composition within at least one chamber of a water treatment system. The composition comprises iron filings comprising at most 5 volume (vol) % of the composition, sand particles comprising at least 80 vol % of the composition, and clay particles comprising at most 5 vol % of the composition. The iron filings, sand particles, and clay particles are mixed together. During the flowing, the clay particles attract the nitrogen and phosphorus compounds, which become absorbed onto a surface of the iron filings and the clay, resulting in a removal of the nitrogen and phosphorus compounds and the generation of reaction products. Nitrogen and phosphorus are then recovered from the reaction products. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 16/829889 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 24/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/043 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/28004 (20130101) B01J 20/28014 (20130101) B01J 20/28054 (20130101) B01J 2220/4825 (20130101) B01J 2220/4831 (20130101) B01J 2220/4893 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) Original (OR) Class C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2201/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787374 | Perreault et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Francois Perreault (Tempe, Arizona); Paul K. Westerhoff (Scottsdale, Arizona); Onur Guven Apul (Lowell, Massachusetts); Shahnawaz Sinha (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Francois Perreault (Tempe, Arizona); Paul K. Westerhoff (Scottsdale, Arizona); Onur Guven Apul (Lowell, Massachusetts); Shahnawaz Sinha (Chandler, Arizona) |
| ABSTRACT | Compositions for bromide removal include a two-dimensional material impregnated with silver. The silver may be impregnated in the two-dimensional material by contacting the two-dimensional material with silver ions in an aqueous solution, allowing the silver ions to adsorb on the two-dimensional material, and drying the two-dimensional material. Removing bromide from an aqueous composition including bromide may include contacting the aqueous composition with a two-dimensional material impregnated with silver, and allowing the bromide to react with the silver to yield silver bromide. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971083 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/14 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/3225 (20130101) B01J 20/3236 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/288 (20130101) Original (OR) Class C02F 1/5245 (20130101) C02F 2101/12 (20130101) C02F 2103/06 (20130101) C02F 2103/007 (20130101) C02F 2103/08 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787424 | Arora et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Brooke Bullock Lao (Leesville, South Carolina); Richard Bonneau (New York, New York); Kevin Drew (Austin, Texas) |
| ABSTRACT | The present invention relates to oxopiperazines that mimic helix αB of the C-terminal transactivation domain of HIF1α. Also disclosed are pharmaceutical compositions containing these oxopiperazines and methods of using these oxopiperazines (e.g., to reduce gene transcription, treat or prevent disorders mediated by interaction of HIF1a with CREB-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, and decrease cell survival and/or proliferation). |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 15/312875 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/80 (20130101) C07C 29/80 (20130101) C07C 29/88 (20130101) C07C 29/88 (20130101) C07C 31/04 (20130101) C07C 31/225 (20130101) Heterocyclic Compounds C07D 241/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787551 | Dichtel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | William R. Dichtel (Ithaca, New York); Deepti Gopalakrishnan (Ithaca, New York) |
| ABSTRACT | Cross-linked polymer networks that are at least partially conjugated (e.g., phenylene vinylene polymer networks). The cross-linked polymer networks may be thin-films disposed on a substrate. The cross-linked polymer network may be covalently bonded to the substrate. The cross-linked polymer networks can be used, for example, in methods of detecting explosives (e.g., RDX (cyclotrimethylenetrinitramine)) and degradation products thereof. |
| FILED | Friday, February 28, 2014 |
| APPL NO | 14/770234 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2325/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1425 (20130101) C09K 2211/1466 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/0057 (20130101) G01N 2021/6432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787579 | Advincula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rigoberto Advincula (Friendswood, Texas); Roderick B. Pernites (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Rigoberto Advincula (Friendswood, Texas); Roderick B. Pernites (Houston, Texas) |
| ABSTRACT | Novel coatings are disclosed prepared from electropolymerization of electropolymerizable monomers-analyte complexes onto a conducting layer or non-conducting of a substrate, where the analyte is removed by electrochemically mediated washing permitting linear molecular sensing of the analyte over a wide concentration range. The coating may also include templating particles deposited on the electrode substrate prior to electropolymerization, where the particles can be removed to form a submicron structured coating. Methods for making and using the coatings are also disclosed. |
| FILED | Saturday, July 09, 2011 |
| APPL NO | 13/179516 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1681 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/34 (20130101) C25D 5/48 (20130101) C25D 9/02 (20130101) C25D 13/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24612 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787672 | Shao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Zengyi Shao (Ames, Iowa); Mingfeng Cao (Ames, Iowa); Miguel Suastegui (Ames, Iowa); Meirong Gao (Ames, Iowa) |
| ABSTRACT | The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/019822 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/10 (20130101) C12N 9/88 (20130101) C12N 15/81 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 2830/002 (20130101) C12N 2830/008 (20130101) C12N 2830/702 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) C12P 7/42 (20130101) C12P 7/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787703 | Storici et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Francesca Storici (Atlanta, Georgia); Jay Hesselberth (Atlanta, Georgia); Kyung Duk Koh (Atlanta, Georgia) |
| ABSTRACT | Genomic DNA contains embedded ribonucleotides (rNMPs) that are incorporated during DNA replication and repair, or formed during DNA damage. The modifications have been linked to genome instability and disease, but no method currently exists to profile their locations genome-wide. rNMP incorporation has been extensively studied in recent years; however, locating sites of rNMP incorporation in genomic DNA has not yet been possible. Disclosed herein is a unique method for mapping rNMPs in genomic DNA that exploits the unique ligation mechanism of Arabidopsis thaliana tRNA ligase (AtRNL), normally involved in tRNA maturation. As disclosed herein AtRNL captures 2′,3′-cyclic phosphate or 2′-phosphate termini of DNA derived from alkaline cleavage of a DNA oligonucleotide (oligo) at an embedded rNMP, ligating the 2′-phosphate end to the 5′-phosphate terminus of the same DNA molecule and producing a ssDNA circle containing an embedded rNMP. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 15/402217 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) Original (OR) Class C12Q 1/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787744 | George et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Steven McClellan George (Boulder, Colorado); Nicholas Ray Johnson (Louisville, Colorado); Jaime Willadean Dumont (Racine, Wisconsin); Amy Elizabeth Marquardt (Chicago, Illinois); Younghee Lee (Boulder, Colorado); David Richard Zywotko (Boulder, Colorado); Aziz Abdulagatov (Boulder, Colorado) |
| ABSTRACT | The invention includes a method of promoting atomic layer etching (ALE) of a surface. In certain embodiments, the method comprises sequential reactions with a metal precursor and a halogen-containing gas. In other embodiments, the etching rate is increased by removing residual species bound to and/or adsorbed onto the surface. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049258 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 4/00 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/465 (20130101) H01L 21/30621 (20130101) H01L 21/31116 (20130101) H01L 21/31122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787750 | Bocarsly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Avantium Knowledge Centre B.V. (Amsterdam, Netherlands) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); Avantium Knowledge Centre B.V. (Amsterdam, Netherlands) |
| INVENTOR(S) | Andrew B. Bocarsly (Plainsboro, New Jersey); Zachary M. Detweiler (Plainsboro, New Jersey) |
| ABSTRACT | A method reducing carbon dioxide to one or more organic products may include steps (A) to (E). Step (A) may introduce an anolyte to a first compartment of an electrochemical cell. The first compartment may include an anode. Step (B) may introduce a catholyte and carbon dioxide to a second compartment of the electrochemical cell. Step (C) may oxidize an indium cathode to produce an oxidized indium cathode. Step (D) may introduce the oxidized indium cathode to the second compartment. Step (E) may apply an electrical potential between the anode and the oxidized indium cathode sufficient for the oxidized indium cathode to reduce the carbon dioxide to a reduced product. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/152852 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) Original (OR) Class C25B 9/08 (20130101) C25B 11/04 (20130101) C25B 11/0452 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788133 | Goldfarb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Nashville, Tennessee); Jason Mitchell (Nashville, Tennessee) |
| ABSTRACT | A directional-control valve is typically comprised of a valve spool that slides linearly within a valve body. The valve body typically includes five internal ports, which are covered or exposed as the spool slides within the body. The typical five-internal-port architecture precludes certain combinations of port connectivity when the spool is in the center position. For example, when the spool is in the center position, providing connectivity between the actuator ports, while simultaneously providing fluid isolation of the supply and exhaust ports, is not directly achievable with a standard five-port architecture. This application describes three embodiments that enable the aforementioned port connectivity when the spool is in the center position. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/794074 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 13/0402 (20130101) F15B 2013/0412 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/07 (20130101) Original (OR) Class F16K 31/0613 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788471 | Wolf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Christian Wolf (Arlington, Virginia); Peng Zhang (Arlington, Virginia) |
| ABSTRACT | The present invention is directed to analytical methods for determining the concentration, and/or stereoisomeric excess, and/or absolute configuration of chiral analytes in a sample. |
| FILED | Friday, June 08, 2018 |
| APPL NO | 16/004206 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/19 (20130101) G01N 31/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788485 | Swager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Shinsuke Ishihara (Cambridge, Massachusetts) |
| ABSTRACT | A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer. |
| FILED | Wednesday, March 08, 2017 |
| APPL NO | 15/453217 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/78 (20130101) G01N 21/6428 (20130101) G01N 33/54386 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788532 | Deutsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Sergej Deutsch (Durham, North Carolina); Krishnendu Chakrabarty (Chapel Hill, North Carolina) |
| ABSTRACT | Embedded processor-based self-test and diagnosis using the compressed test data is described for ICs having on-chip memory. Techniques for compressing the test data before the compressed test data is transferred to a device under test (DUT) are also described. A modified LZ77 algorithm can be used to compress strings of test data in which don't care bits are handled by assigning a value to the don't care bits according to a longest match in the window as the data is being encoded. The compressed test data can be decompressed at the DUT using a software program transferred by the automated test equipment (ATE) to the DUT with the compressed test data. Decompression and diagnostics can be carried out at the DUT using an embedded processor and the on-chip memory. Results from the diagnostics can be read by the ATE. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/827266 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2834 (20130101) G01R 31/318547 (20130101) Original (OR) Class Electric Digital Data Processing G06F 11/263 (20130101) Static Stores G11C 5/04 (20130101) G11C 29/36 (20130101) G11C 29/40 (20130101) G11C 29/44 (20130101) G11C 29/4401 (20130101) G11C 29/56004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10789713 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | A method and system for registration of a multi-dimensional image include defining an input image and a reference image in the same fixed Cartesian grid, then mapping locations within the reference image and the input image to phase space using a Hamiltonian function to define a symplectomorphic map, where the map is embedded in an energy shell. The mapping step is iterated until a sequence of energy shells is created. The energy shells are used generate curvilinear mapping grid which is then applied to the first image to generate a registered output image data. The data may be preconditioned to account for nearest neighbor coupling and/or to equalize the dimensionality of the images. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 16/071418 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0016 (20130101) Original (OR) Class G06T 7/37 (20170101) G06T 11/008 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790144 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nathan Newman (Tempe, Arizona); Mahmoud Vahidi (Tempe, Arizona); Stephen Lehner (Tempe, Arizona); Peter Buseck (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Nathan Newman (Tempe, Arizona); Mahmoud Vahidi (Tempe, Arizona); Stephen Lehner (Tempe, Arizona); Peter Buseck (Tempe, Arizona) |
| ABSTRACT | A method for preparing a device having a film on a substrate is disclosed. In the method, a film is deposited on a substrate. The film includes a single-crystalline or poly-crystalline semiconducting thin film. The single-crystalline or poly-crystalline semiconducting thin film is formed by sequential evaporation of a first and a second element. One example device prepared by the method includes a silicon substrate and a film on the substrate, wherein the film includes semiconducting and single- or poly-crystalline pyrite as the compound. |
| FILED | Monday, June 23, 2014 |
| APPL NO | 14/900307 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02417 (20130101) H01L 21/02568 (20130101) Original (OR) Class H01L 21/02614 (20130101) H01L 21/02631 (20130101) H01L 29/04 (20130101) H01L 29/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790203 | Basol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Active Layer Parametrics, Inc. (Scotts Valley, California) |
| ASSIGNEE(S) | Active Layer Parametrics, Inc. (Scotts Valley, California) |
| INVENTOR(S) | Bulent M. Basol (Manhattan Beach, California); Abhijeet Joshi (Los Angeles, California); Jalal Ashjaee (Cupertino, California) |
| ABSTRACT | Methods, tools and systems for full characterization of thin and ultra-thin layers employed in advanced semiconductor device structures are disclosed. |
| FILED | Tuesday, April 25, 2017 |
| APPL NO | 16/095930 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2648 (20130101) G01R 31/2831 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/321 (20130101) H01J 37/3244 (20130101) H01J 37/32963 (20130101) H01J 2237/3341 (20130101) H01J 2237/24564 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/67069 (20130101) H01L 21/67253 (20130101) H01L 22/12 (20130101) H01L 22/14 (20130101) H01L 22/20 (20130101) H01L 22/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790738 | Mhiesan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Haider Mhiesan (Fayetteville, Arkansas); Roy A. McCann (Fayetteville, Arkansas); H. Alan Mantooth (Fayetteville, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haider Mhiesan (Fayetteville, Arkansas); Roy A. McCann (Fayetteville, Arkansas); H. Alan Mantooth (Fayetteville, Arkansas) |
| ABSTRACT | A faulted switch isolated replacement path for a power converter is provided using replacement switches connected to an isolated node. The replacement switches can be controlled by normal operating signals. The replacement path is isolated by isolation switches during normal operation. During a fault condition, the isolating switches are activated such that the isolated node is selectively connected to the appropriate power output. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 16/420539 |
| ART UNIT | 2839 — Optics |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 7/483 (20130101) H02M 7/53871 (20130101) H02M 2001/325 (20130101) H02M 2007/4835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790779 | Balog, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Robert S. Balog, Jr. (College Station, Texas); Zhan Wang (Sunnyvale, California) |
| ABSTRACT | In some examples, a system comprises a first component; a second component configured to receive signals from the first component via one or more wires; and a controller. In at least some examples, the controller is coupled to the one or more wires and is trained with a classification model to distinguish between signals indicating arc events and signals not indicating arc events. In at least some example, the controller is further configured to: receive the signals; extract features that are at least partially related to the received signals; classify the extracted features using the classification model; determine an occurrence of the arc event based on the classification; and provide an output signal indicating an arc event. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000694 |
| ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/0265 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02021 (20130101) Emergency Protective Circuit Arrangements H02H 1/0015 (20130101) H02H 1/0092 (20130101) H02H 7/20 (20130101) H02H 7/205 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/30 (20141201) Original (OR) Class H02S 50/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790946 | Melodia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts) |
| ABSTRACT | A system and method for transmitting data ultrasonically through biological tissue employs a network of a plurality of nodes, at least a portion of the nodes implantable within the biological tissue. At least one implanted node includes a transmitter having an orthogonal frequency division multiplex signal generator to encode an ultrasonic signal for transmission through the biological tissue to an ultrasonic receiver at another node. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/552369 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 1/0057 (20130101) H04L 5/0012 (20130101) Original (OR) Class H04L 27/0008 (20130101) H04L 27/362 (20130101) H04L 27/2053 (20130101) H04L 27/2602 (20130101) H04L 27/2626 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10786805 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Stephen C. Jensen (Chicago, Illinois); Emily A. Weiss (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions comprising cadmium sulfide quantum dot photocatalysts and methods and systems utilizing as much (e.g., for the reduction of a nitrobenzene to an aniline). |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/074169 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/123 (20130101) B01J 19/127 (20130101) B01J 27/04 (20130101) Original (OR) Class B01J 35/002 (20130101) B01J 35/004 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Acyclic or Carbocyclic Compounds C07C 211/46 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10786811 | Koh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Julia Litvinov (Galveston, Texas) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Julia Litvinov (Galveston, Texas) |
| INVENTOR(S) | Chung-Yan Koh (Dublin, California); Anup K. Singh (Danville, California); Julia Litvinov (Galveston, Texas) |
| ABSTRACT | The present invention relates to methods of detecting one or more targets of interest in a sample. In one instance, the target can be correlated to an active infection (e.g., by a virus and/or a bacterium). Methods can include treating the sample with a dissociation agent, thereby releasing the target of interest for more accurate detection (e.g., by use of a sedimentation-based centrifugal microfluidic devices). Also described herein are microfluidic devices and systems for use with a dissociation agent. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/785708 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2300/0864 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5302 (20130101) G01N 35/08 (20130101) G01N 35/00069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787639 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jian Gao (Richmond, California); Trent R. Northen (Walnut Creek, California); Kyle M. Lewald (Lafayette, California); Lloyd T. Cornmesser (San Ramon, California); Peter F. Andeer (Oakland, California) |
| ABSTRACT | Disclosed herein are systems, methods, and devices for determining plant-microbe interactions. In some embodiments, the device comprises: a root chamber configured to allow a root of a plant to grow, wherein the root chamber is connected with: an inlet channel for introducing a medium into the root chamber, an outlet channel for collecting plant exudates and metabolites, and a plant reservoir for the plant shoot of the plant to grow. |
| FILED | Thursday, April 26, 2018 |
| APPL NO | 15/963887 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 63/00 (20130101) A01N 63/00 (20130101) A01N 63/30 (20200101) Apparatus for Enzymology or Microbiology; C12M 23/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787749 | Xiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Chengxiang Xiang (San Marino, California); Xinghao Zhou (Pasadena, California); Ke Sun (Pasadena, California); Ryan J. Jones (Pasadena, California); Nathan S. Lewis (La Canada Flintridge, California) |
| ABSTRACT | A solar fuels generator includes an anolyte and a catholyte in contact with a separator. The separator is configured such that the pH of the anolyte and the pH of the catholyte are each held at a steady state pH level during operation of the solar fuels generator. The steady state pH level of the anolyte is different from the steady state pH level of the catholyte. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 15/909764 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) C25B 1/10 (20130101) C25B 3/04 (20130101) Original (OR) Class C25B 11/0447 (20130101) C25B 13/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) Y02E 70/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787892 | Legg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| INVENTOR(S) | Robert Legg (Newport News, Virginia); Thomas Powers (Poquoson, Virginia) |
| ABSTRACT | A system and method for the in situ processing of internal SRF cavity surfaces to reduce field emission and improve maximum gradient. An electromagnetic radiation source is introduced in the bore of a superconducting cavity to enhance ionization or dissociation of gases which then remove contaminants from the surface of the cavity, either through direct surface bombardment, chemical reaction or through the production of radiation which interacts with the contaminants. An RF or low frequency electromagnetic field may be established in the cavity which further enhances the ionization or dissociation process and may cause the ions to bombard sites with enhanced electric fields. The invention removes the requirement that the RF field be sufficient by itself to ionize gas in the cavity. |
| FILED | Thursday, September 12, 2019 |
| APPL NO | 16/568370 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 36/04 (20130101) E21B 43/247 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787959 | Roychoudhury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Subir Roychoudhury (Madison, Connecticut); Richard Mastanduno (Milford, Connecticut); Eric Edward Allocco (Cheshire, Connecticut); Saurabh Vilekar (Woodbridge, Connecticut) |
| ABSTRACT | A process of operating a spark-ignited internal combustion engine (SI-ICE) with improved fuel efficiency and reduced emissions including under steady state and under lean-operating conditions at high overall air to fuel (AFR) ratios. A first supply of high octane hydrocarbon fuel, such as gasoline or natural gas, and a first supply of oxidant are fed to a fuel reformer to produce a gaseous reformate with a reforming efficiency of greater than 75 percent relative to equilibrium. The gaseous reformate is mixed with a second supply of oxidant, after which the resulting reformate blended oxidant is fed with a second supply of high octane hydrocarbon fuel to the SI-ICE for combustion. Steady state fuel efficiency is improved by more than 3 percent, when the reformate comprises from greater than about 1 to less than about 18 percent of the total volume of reformate blended oxidant fed to the engine. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 16/463409 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/464 (20130101) B01J 35/06 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/386 (20130101) C01B 3/388 (20130101) C01B 2203/0261 (20130101) C01B 2203/1064 (20130101) C01B 2203/1247 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/12 (20130101) C10L 1/023 (20130101) C10L 1/1233 (20130101) C10L 10/02 (20130101) C10L 2200/0277 (20130101) C10L 2200/0281 (20130101) C10L 2200/0423 (20130101) C10L 2230/22 (20130101) C10L 2270/023 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 43/12 (20130101) F02B 47/06 (20130101) F02B 51/02 (20130101) Original (OR) Class F02B 2043/103 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/36 (20160201) F02M 27/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788568 | Loui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Hung Loui (Albuquerque, New Mexico); Brianna Maio (Las Cruces, New Mexico) |
| ABSTRACT | A radar system wherein a radar return is channelized by frequency into a plurality of channels, and each of the channels is sampled by a respective analog-to-digital converter that has a sampling rate less than the Nyquist rate of the radar return. The digitally sampled channel signals are Fourier transformed into the frequency domain, where each of the frequency-domain channel signals is matched-filtered according to a respective partial matched filter. The channel signals are then transformed back to the time domain, whereupon they are added together to generate the impulse response of the radar system responsive to the radar return. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025843 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/295 (20130101) Original (OR) Class G01S 13/0209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788590 | Payne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jason A. Payne (Albuquerque, New Mexico); John J. Mason (Albuquerque, New Mexico); Albert Hummel (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies pertaining to integrating a positioning or timing solution from an alternative position, navigation, or timing (PNT) system into a satellite-based-navigation system are described herein. The PNT system generates a position/timing (P/T) solution that indicates a current position or current time of the PNT system. The P/T solution is provided as input to a simulation of a satellite constellation of the satellite-based-navigation system, and a constellation signal is generated based on the simulation and the P/T solution. The constellation signal is formatted according to a navigation signal format of the satellite-based-navigation system such that when the constellation signal is provided to a receiver of the satellite-based-navigation system, the receiver computes a P/T solution that indicates the current position or the current time identified by the PNT system. |
| FILED | Wednesday, May 09, 2018 |
| APPL NO | 15/975082 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/24 (20130101) G01S 5/14 (20130101) G01S 19/36 (20130101) G01S 19/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788633 | Leigh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Kevin B. Leigh (Houston, Texas); Paul Kessler Rosenberg (Palo Alto, California); Sagi Mathai (Palo Alto, California); Wayne Victor Sorin (Palo Alto, California); Michael Renne Ty Tan (Palo Alto, California); Georgios Panotopoulos (Palo Alto, California) |
| ABSTRACT | In example implementations, an apparatus is provided. The apparatus includes an optical transmission component and an optical reception component. The optical transmission component includes a plurality of lasers and a transmit filter. The plurality of lasers each emit a different wavelength of light. The transmit filter includes a plurality of different regions that correspond to one of the different wavelengths of light emitted by the plurality of lasers. The optical reception component includes a plurality of photodiodes and a complementary reverse order (CRO) filter. The CRO filter includes a same plurality of different regions as the transmit filter in a reverse order. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966359 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4215 (20130101) Original (OR) Class Transmission H04B 10/25 (20130101) H04B 10/67 (20130101) H04B 10/506 (20130101) Multiplex Communication H04J 14/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788689 | Lentine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Anthony L. Lentine (Albuquerque, New Mexico); Christopher DeRose (Victor, New York); Douglas Chandler Trotter (Albuquerque, New Mexico); Thomas A. Friedmann (Albuquerque, New Mexico); Michael Gehl (Albuquerque, New Mexico); Nicholas Boynton (Albuquerque, New Mexico) |
| ABSTRACT | In an electro-optical modulator, an electro-optical modulation layer is bonded to a cladding layer that overlies a substrate. A modulation zone waveguide is optically coupled to the electro-optical modulation layer and optically coupled to an I/O waveguiding structure embedded in the cladding layer. The I/O waveguiding structure is conformed to guide input light toward the modulation zone waveguide and to guide output light away from the modulation zone waveguide. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/656922 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0356 (20130101) Original (OR) Class G02F 1/2255 (20130101) G02F 2001/212 (20130101) G02F 2202/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790065 | Subhash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Ghatu Subhash (Gainesville, Florida); Ronald Howard Baney (Gainesville, Florida); James S. Tulenko (Gainesville, Florida); Edward McKenna, III (Hillsboro, Oregon); Lihao Ge (Gainesville, Florida); Sunghwan Yeo (Gainesville, Florida) |
| ABSTRACT | Embodiments of the invention are directed to a method for production of a nuclear fuel pellet by spark plasma sintering (SPS), wherein a fuel pellet with more than 80% TD or more than 90% TD is formed. The SPS can be performed with the imposition of a controlled uniaxial pressure applied at the maximum temperature of the processing to achieve a very high density, in excess of 95% TD, at temperatures of 850 to 1600° C. The formation of a fuel pellet can be carried out in one hour or less. In an embodiment of the invention, a nuclear fuel pellet comprises UO2 and a highly thermally conductive material, such as SiC or diamond. |
| FILED | Thursday, August 15, 2013 |
| APPL NO | 14/420702 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 3/045 (20190101) G21C 3/62 (20130101) Original (OR) Class G21C 21/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790070 | Larsen, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | George K. Larsen, III (Aiken, South Carolina); Simona E. Hunyadi Murph (North Augusta, South Carolina) |
| ABSTRACT | Radiation detectors and methods of using the radiation detectors that provide a route for surface decontamination during use are described. The detectors utilize light illumination of an internal surface during use. Light is in the longer UV to near-infrared spectra and desorbs contamination from internal surfaces of radiation detectors. The methods can be carried out while the detectors are in operation, preventing the appearance of the negative effects of radioactive and non-radioactive contamination during a detection regime and following a detection regime. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/125954 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 7/0057 (20130101) Measurement of Nuclear or X-radiation G01T 1/185 (20130101) G01T 7/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790398 | Antunez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Priscilla D. Antunez (Tarrytown, New York); Bruce A. Ek (Pelham Manor, New York); Richard A. Haight (Mahopac, New York); Ravin Mankad (Mumbai, India); Saurabh Singh (Yonkers, New York); Teodor K. Todorov (Yorktown Heights, New York) |
| ABSTRACT | Kesterite photovoltaic devices having a back surface field layer are provided. In one aspect, a method of forming a photovoltaic device includes: forming a complete photovoltaic device having a substrate, an electrically conductive layer on the substrate, an absorber layer on the electrically conductive layer, a buffer layer on the absorber layer, and a transparent front contact on the buffer layer; removing the substrate and the electrically conductive layer from the complete photovoltaic device to expose a backside surface of the absorber layer; forming a passivating layer on the backside surface of the absorber layer; and forming a high work function back contact on the passivating layer. A photovoltaic device having a passivating layer is also provided. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/009098 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/072 (20130101) H01L 31/0326 (20130101) Original (OR) Class H01L 31/1864 (20130101) H01L 31/1868 (20130101) H01L 31/1884 (20130101) H01L 31/1896 (20130101) H01L 31/02167 (20130101) H01L 31/022425 (20130101) H01L 31/022441 (20130101) H01L 31/022466 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790489 | Lampe-Onnerud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cadenza Innovation, Inc. (Wilton, Connecticut) |
| ASSIGNEE(S) | Cadenza Innovation, Inc. (Wilton, Connecticut) |
| INVENTOR(S) | Maria Christina Lampe-Onnerud (Wilton, Connecticut); Tord Per Jens Onnerud (Wilton, Connecticut); Jay Jie Shi (Acton, Massachusetts); Michael Suba (Sandy Hook, Connecticut); Joshua Liposky (Seymour, Connecticut) |
| ABSTRACT | A multi-core lithium ion battery includes a sealed enclosure and a support member disposed within the sealed enclosure. The sealed enclosure may be fabricated with a clamshell configuration. The sealed enclosure may further include at least two support members housed within individual compartments, separated by shared wall(s). The support member(s) includes a plurality of cavities and a plurality of lithium ion core members which are disposed within the plurality of cavities. The battery may further include a plurality of cavity liners, each of which is positioned between a corresponding one of the lithium ion core members and a surface of a corresponding one of the cavities. The hermetically sealed enclosure may be formed using a clamshell configuration. Structures may be included in proximity to or in contact with the lithium ion core members to control gas/fluid flow therefrom. |
| FILED | Tuesday, March 20, 2018 |
| APPL NO | 15/926433 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/34 (20130101) H01M 2/206 (20130101) H01M 2/0242 (20130101) H01M 2/347 (20130101) H01M 2/1016 (20130101) H01M 2/1027 (20130101) H01M 2/1077 (20130101) Original (OR) Class H01M 2/1094 (20130101) H01M 2/1686 (20130101) H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/6551 (20150401) H01M 16/00 (20130101) H01M 2010/4271 (20130101) H01M 2200/00 (20130101) H01M 2200/103 (20130101) H01M 2220/10 (20130101) H01M 2220/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790508 | Thackeray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Michael M. Thackeray (Naperville, Illinois); Jason R. Croy (Plainfield, Illinois); Brandon R. Long (Plainfield, Illinois); Joong Sun Park (Woodridge, Illinois); Eungje Lee (Naperville, Illinois) |
| ABSTRACT | An electrode material comprising a composite lithium metal oxide, which in an initial state has the formula: y[xLi2MO3.(1−x)LiM′O2].(1−y)Li1+dMn2−z−dM″zO4; wherein 0≤x≤1; 0.75≤y<1; 0<z≤2; 0≤d≤0.2; and z−d≤2. M comprises one or more metal ions that together have an average oxidation state of +4; M′ comprises one or more metal ions that together have an average oxidation state of +3; and M″ comprises one or more metal ions that together with the Mn and any excess proportion of lithium, “d”, have a combined average oxidation state between +3.5 and +4. The Li1+dMn2−z−dM″zO4 component comprises a spinel structure, each of the Li2MO3 and the LiM′O2 components comprise layered structures, and at least one of M, M′, and M″ comprises Co. Cells and batteries comprising the electrode material also are described. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020403 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 10/052 (20130101) H01M 2220/20 (20130101) H01M 2220/30 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790514 | Pivovar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Bryan Pivovar (Arvada, Colorado); Shaun Alia (Lakewood, Colorado) |
| ABSTRACT | Aspects disclosed herein relate to methods for producing nanostructured metal catalysts that can be used in various alternative fuel applications. |
| FILED | Wednesday, November 04, 2015 |
| APPL NO | 14/932740 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0044 (20130101) B22F 9/18 (20130101) B22F 9/20 (20130101) B22F 9/24 (20130101) B22F 2201/03 (20130101) B22F 2201/013 (20130101) B22F 2301/15 (20130101) B22F 2301/25 (20130101) B22F 2304/05 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) Original (OR) Class H01M 4/9041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10786830 | Straka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sharon A. Straka (Greenbelt, Maryland); Mark M. Hasegawa (Greenbelt, Maryland); Kenneth M. O'Connor (Greenbelt, Maryland); Victoria J. Stotzer (Greenbelt, Maryland) |
| ABSTRACT | A system, apparatus, composition and method employing a dust mitigation coating that also mitigates or repels water, ice, and other liquids. Techniques to coat the surfaces of equipment and items with these dust, liquid, and ice mitigation coatings, minimizing or eliminating mission problems caused by dust, liquid, or ice accumulation, particularly in outer space or on another planetary body or moon. Further, the dust mitigation coatings should exhibit a Lotus-like effect, making the coated surfaces ultra-hydrophobic. The present invention is also directed to techniques for improving the functioning of terrestrial-based equipment and systems where dust, liquid, or ice accumulation is a problem, such as in hospitals and other health contexts to prevent contamination. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/215040 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/002 (20130101) B05D 3/105 (20130101) B05D 3/0254 (20130101) B05D 5/083 (20130101) Original (OR) Class B05D 7/51 (20130101) B05D 2203/35 (20130101) B05D 2504/00 (20130101) B05D 2601/22 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 23/28 (20130101) C08L 63/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/18 (20130101) C09K 3/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787242 | Nguyen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Nhan T. Nguyen (Santa Clara, California) |
| ABSTRACT | There is provided an aerodynamic control apparatus for an air vehicle comprising a flap system including a first spanwise flap segment to be arranged on a first side of an air vehicle, a second spanwise flap segment to be arranged on the first side of the air vehicle, and a controller to actuate the first spanwise flap segment to a first flap deflection and the second spanwise flap segment to a second flap deflection, wherein the first spanwise flap segment at the first flap deflection and the second spanwise flap segment at the second flap deflection form a piecewise continuous trailing edge. |
| FILED | Tuesday, January 05, 2016 |
| APPL NO | 14/988627 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/14 (20130101) B64C 3/50 (20130101) Original (OR) Class B64C 7/00 (20130101) B64C 9/20 (20130101) B64C 9/24 (20130101) B64C 9/26 (20130101) B64C 2003/147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787394 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POWDERMET, INC. (Euclid, Ohio) |
| ASSIGNEE(S) | Powdermet, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609165 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/58 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0645 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) C04B 2235/77 (20130101) C04B 2235/483 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787569 | Meador et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Mary Ann B. Meador (Strongsville, Ohio); Jarrod C. Williams (Lakewood, Ohio) |
| ABSTRACT | Polyamide aerogels and methods of making the same are discussed. One example method can include the act of creating a mixture of at least one diamine with at least one diacid chloride in a first solvent. The mixture can comprise a plurality of amine capped polyamide oligomers. Such a method can also include the acts of adding a cross-linking agent to the mixture to create a gel and performing one or more solvent exchanges to remove the first solvent. Additionally, such a method can include the act of subjecting the gel to supercritical drying to polyamide aerogel. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978870 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/26 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2205/026 (20130101) C08J 2377/10 (20130101) Compositions of Macromolecular Compounds C08L 77/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787575 | Abraham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Nithin S. Abraham (Silver Spring, Maryland); Mark M. Hasegawa (Highland, Maryland); Sharon A. Straka (Glenelg, Maryland); John C. Petro (Greenbelt, Maryland) |
| ABSTRACT | A black molecular adsorber coating (MAC-B) composition is provided that exhibits adsorptive capabilities and reduces the effects of optical path degradation and system performance degradation when formed into a black coating having low reflectivity. The coating can be used in stray light control applications or within light paths between optical systems to absorb light and reduce the effects of optical path degradation. The coating can be used in vacuum systems to adsorb molecular contaminants and to reduce vacuum pressure levels. The coating composition can be sprayed onto interior surfaces, such as optical cavities of cameras, telescopes, lasers, baffles, detectors systems, and electronics boxes to control performance degradation due to outgassed molecular contaminants. The sprayable black molecular adsorber coating composition eliminates the major drawbacks of previous puck style adsorbers, slurry coated systems, and other bulky adsorber systems, resulting in cost savings, mass savings, easier utilization, greater adsorber surface area, more flexibility, and higher efficiency. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 15/657473 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Original (OR) Class C09D 5/00 (20130101) C09D 5/16 (20130101) C09D 7/70 (20180101) C09D 163/00 (20130101) C09D 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788462 | Troy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | James J. Troy (Issaquah, Washington); Daniel J. Wright (Mercer Island, Washington); Scott W. Lea (Renton, Washington); Gary Ernest Georgeson (Tacoma, Washington) |
| ABSTRACT | A dual function non-destructive inspection apparatus comprises a frame structure, a thermographic inspection system, a displacement system, and an ultrasonic inspection system. The frame structure has a channel, a first end, and a second end. The channel extends through the frame structure from the first end to the second end. The thermographic inspection system is associated with the first end of the frame structure. The displacement system is connected to the second end of the frame structure. The ultrasonic inspection system is connected to the displacement system such that the displacement system moves the ultrasonic inspection system relative to the channel of the frame structure. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/024347 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/72 (20130101) G01N 29/04 (20130101) G01N 29/265 (20130101) Original (OR) Class G01N 29/4454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790500 | Templeton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Alexis Templeton (Boulder, Colorado); Julie Cosmidis (Boulder, Colorado) |
| ABSTRACT | The invention provides methods of preparing carbon/sulfur composites. In certain embodiments, the composites comprise multidimensional carbon tubular and/or spherical networks loaded with elemental sulfur, as well as compositions comprising such composites. |
| FILED | Tuesday, August 16, 2016 |
| APPL NO | 15/753106 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 17/40 (20130101) C01B 32/05 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/54 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/32 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/136 (20130101) H01M 4/364 (20130101) H01M 4/625 (20130101) H01M 4/1397 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10790778 | Rakow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Composite Technology Development, Inc. (Lafayette, Colorado) |
| ASSIGNEE(S) | Composite Technology Development, Inc. (Lafayette, Colorado) |
| INVENTOR(S) | Alexi Rakow (Boulder, Colorado); Naseem Munshi (Lafayette, Colorado); Dana Turse (Broomfield, Colorado); Doug Richardson (Westminster, Colorado); Larry Adams (Thornton, Colorado) |
| ABSTRACT | Deployable solar panels are disclosed. In some embodiments, the deployable solar panel includes an extendable member comprising a composite material and having a length and a width; a plurality of hinges, each of the plurality of hinges extending across the width of the extendable member, the plurality of hinges comprising composite material and a shape memory polymer; and a plurality of solar panels coupled with the extendable member. In some embodiments, the deployable solar panel includes a lenticular shape extending along the length of the extendable member. |
| FILED | Wednesday, November 22, 2017 |
| APPL NO | 15/820676 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/40 (20141201) H02S 30/20 (20141201) Original (OR) Class H02S 40/40 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10787646 | Estes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary K. Estes (Houston, Texas); David Graham (Houston, Texas); Robert Legare Atmar (Houston, Texas); Sue Ellen Crawford (Conroe, Texas); Khalil Ettayebi (Pearland, Texas); Kosuke Murakami (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure concern systems, methods, and/or compositions for cultivation of mammalian viruses, including at least human noroviruses and sapoviruses within the Caliciviridae family of viruses. The ex vivo culture systems include intestinal enteroids in combination with bile or a functionally active fraction or component thereof. In specific embodiments, the culture system is utilized to test inactivation compounds for therapeutic or environmental efficacy and to test contaminated comestibles and/or environmental entities for determination of the presence of infectious virus. Furthermore, antiviral compositions may be tested using systems of the disclosure, including drugs, small molecule inhibitors, and biologies such as neutralizing monoclonal antibodies. |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/763695 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0679 (20130101) C12N 7/00 (20130101) C12N 7/02 (20130101) Original (OR) Class C12N 2770/16051 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10787678 | Adang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Michael J. Adang (Athens, Georgia); Gang Hua (Athens, Georgia) |
| ABSTRACT | The subject invention relates in part to a combination of a cadherin peptide derived from Alphitobius diaperinus and a Cry protein capable of inhibiting an insect. In certain embodiments, the combination is capable of overcoming Cry protein resistance in insects that are resistant to the Cry protein alone. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/426000 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/10 (20200101) Peptides C07K 14/325 (20130101) C07K 14/43563 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8286 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10787373 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A method of water treatment includes flowing water that includes nitrogen and phosphorus compounds through a sorption media composition within at least one chamber of a water treatment system. The composition comprises iron filings comprising at most 5 volume (vol) % of the composition, sand particles comprising at least 80 vol % of the composition, and clay particles comprising at most 5 vol % of the composition. The iron filings, sand particles, and clay particles are mixed together. During the flowing, the clay particles attract the nitrogen and phosphorus compounds, which become absorbed onto a surface of the iron filings and the clay, resulting in a removal of the nitrogen and phosphorus compounds and the generation of reaction products. Nitrogen and phosphorus are then recovered from the reaction products. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 16/829889 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 24/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/043 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/28004 (20130101) B01J 20/28014 (20130101) B01J 20/28054 (20130101) B01J 2220/4825 (20130101) B01J 2220/4831 (20130101) B01J 2220/4893 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) Original (OR) Class C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2201/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10788384 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | An Chen (Ames, Iowa); Daji Qiao (Ames, Iowa); Long Que (Ames, Iowa) |
| ABSTRACT | A method, apparatus, and system to quantify tension forces of the anchor bolts for, e.g., SLTS support structures. A sensing assembly comprising one or more washers is installed along an anchor bolt. The sensing assembly comprises two spaced-apart surfaces between which a capacitance can be measured if electrical potential is created between the surfaces. The capacitance between the surfaces can be calibrated to bolt tension based on the relative distance between the surfaces. An RFRD circuit is connected to the two surfaces. An RF interrogation signal can supply the electrical potential and allow a reading of the responsive capacitance between surfaces to convert the capacitance reading into a bolt tension. Additionally, the introduction of the battery-free RFRD allows data to be acquired wirelessly from a distance, enabling an entirely new method of inspection. With minimum additional hardware cost, it provides a cost-effective way to replace traditional bolt installation and inspection methods. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885263 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 31/028 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/14 (20130101) G01L 5/243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 10791445 | Schreib et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AECOM (Los Angeles, California) |
| ASSIGNEE(S) | AECOM (Los Angeles, California) |
| INVENTOR(S) | Benjamin Schreib (Baltimore, Maryland); Michael House (Laurel, Maryland); Samuel McClintock (Williamsburg, Virginia); David Rein (Ann Arbor, Michigan); Navid Yazdi (Ann Arbor, Michigan) |
| ABSTRACT | A system for providing environmental wave data from floating buoys and equipment is based on the GRID tag system, which includes Geo-Referencing Identification (GRID) tag, GRID satellite (GRIDSAT) tag and associated cloud infrastructure and user interface meet the objectives of a robust global tagging and tracking system. The wave characterization module (WCM) system adds wave detection and computation to the GRID tag system. The WCM tag can be used to identify and track floating equipment while also providing local wave characteristics while communicating with other tags via mesh radio. The WCM-sat tag includes a satellite modem, global positioning system (GPS) receiver, and mesh radio to send wave and location data to a remote user. A WCM buoy includes the WCM-sat equipment in a free-floating buoy to report remote oceanic conditions. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125354 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) Wireless Communication Networks H04W 4/70 (20180201) Original (OR) Class H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 10787705 | Esfandyarpour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
| ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/896572 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5438 (20130101) G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10789194 | Dennison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Larry R. Dennison (Mendon, Massachusetts); Mark Hummel (Franklin, Massachusetts); Glenn Dearth (Groton, Massachusetts) |
| ABSTRACT | Systems and techniques for synchronizing transactions between processing devices on an interconnection network are provided. Upon receiving a stream of posted transactions followed by a flush transaction from a source processing device connected to the interconnection network, the flush transaction is trapped before it enters the interconnecting network. Subsequently, based on monitoring for responses received from a destination processing device for transactions corresponding to the posted transactions, a flush response is generated and returned to the source processing device. The described techniques enable efficient synchronizing posted writes, posted atomics and the like over complex interconnection fabrics such that a first GPU can write data to a second GPU so that a third GPU can safely consume the data written to the second GPU. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/364565 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3877 (20130101) G06F 12/0891 (20130101) G06F 13/4022 (20130101) Original (OR) Class G06F 2213/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10788384 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | An Chen (Ames, Iowa); Daji Qiao (Ames, Iowa); Long Que (Ames, Iowa) |
| ABSTRACT | A method, apparatus, and system to quantify tension forces of the anchor bolts for, e.g., SLTS support structures. A sensing assembly comprising one or more washers is installed along an anchor bolt. The sensing assembly comprises two spaced-apart surfaces between which a capacitance can be measured if electrical potential is created between the surfaces. The capacitance between the surfaces can be calibrated to bolt tension based on the relative distance between the surfaces. An RFRD circuit is connected to the two surfaces. An RF interrogation signal can supply the electrical potential and allow a reading of the responsive capacitance between surfaces to convert the capacitance reading into a bolt tension. Additionally, the introduction of the battery-free RFRD allows data to be acquired wirelessly from a distance, enabling an entirely new method of inspection. With minimum additional hardware cost, it provides a cost-effective way to replace traditional bolt installation and inspection methods. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885263 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 31/028 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/14 (20130101) G01L 5/243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10787394 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POWDERMET, INC. (Euclid, Ohio) |
| ASSIGNEE(S) | Powdermet, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609165 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/58 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0645 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) C04B 2235/77 (20130101) C04B 2235/483 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10787373 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A method of water treatment includes flowing water that includes nitrogen and phosphorus compounds through a sorption media composition within at least one chamber of a water treatment system. The composition comprises iron filings comprising at most 5 volume (vol) % of the composition, sand particles comprising at least 80 vol % of the composition, and clay particles comprising at most 5 vol % of the composition. The iron filings, sand particles, and clay particles are mixed together. During the flowing, the clay particles attract the nitrogen and phosphorus compounds, which become absorbed onto a surface of the iron filings and the clay, resulting in a removal of the nitrogen and phosphorus compounds and the generation of reaction products. Nitrogen and phosphorus are then recovered from the reaction products. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 16/829889 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 24/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/043 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/28004 (20130101) B01J 20/28014 (20130101) B01J 20/28054 (20130101) B01J 2220/4825 (20130101) B01J 2220/4831 (20130101) B01J 2220/4893 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) Original (OR) Class C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2201/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 29, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20200929.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page