FedInvent™ Patents
Patent Details for Tuesday, October 06, 2020
This page was updated on Monday, March 27, 2023 at 06:12 AM GMT
Department of Health and Human Services (HHS)
| US 10791722 | Hay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Bruce A. Hay (Encino, California); Omar S. Akbari (Pasadena, California); Anna B. Buchman (Pasadena, California) |
| ABSTRACT | Embodiments provided herein relate to systems for synthetically-engineered reciprocal chromosomal translocation for gene insertion into a population of organisms such as insects. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164452 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0339 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2227/706 (20130101) A01K 2267/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791948 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bin He (Minneapolis, Minnesota); Long Yu (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for cardiac activation imaging includes non-invasively or minimally invasively acquiring data about an electrical activation of a heart of a subject using at least one sensor. An activation image of the heart of the subject is reconstructed using a weighted sparse constrained reconstruction. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103034 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/042 (20130101) A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/742 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/04085 (20130101) A61B 5/6852 (20130101) A61B 5/7282 (20130101) A61B 6/032 (20130101) A61B 6/503 (20130101) A61B 6/5205 (20130101) A61B 2576/023 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791989 | Haris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mohammad Haris (Philadelphia, Pennsylvania); Anup Singh (Philadelphia, Pennsylvania); Kejia Cai (Elkins Park, Pennsylvania); Ravinder Reddy (Gladwyne, Pennsylvania); Feliks Kogan (Philadelphia, Pennsylvania); Ravi Prakash Reddy Nanga (Philadelphia, Pennsylvania); Hari Hariharan (Mount Laurel, New Jersey) |
| ABSTRACT | A non-invasive imaging approach using CEST and MRS may be used to monitor the cleavage of the poly-L-glutamate (PLG) backbone. The cleavage of PLG by cathespsin B can expose exchangeable —NH2 protons in the PLG that are then monitored non-invasively through CEST. The technique can provide direct information on malignant tissue and tumor aggressiveness, and can also be used to monitor treatment. |
| FILED | Friday, April 04, 2014 |
| APPL NO | 14/781441 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4839 (20130101) A61B 5/4848 (20130101) Original (OR) Class A61B 5/4866 (20130101) A61B 5/14546 (20130101) A61B 2560/0475 (20130101) A61B 2576/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/007 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) G01R 33/483 (20130101) G01R 33/5601 (20130101) G01R 33/5605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791992 | Desai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Jaydev P. Desai (Marietta, Georgia); Hardik Jeetendra Pandya (Bangalore, India); Kihan Park (Atlanta, Georgia) |
| ABSTRACT | A system for automated simultaneous measurements of multiple parameters (mechanical, electrical and/or thermal) of biological tissues includes a base platform supporting a biochip holder module with a biochip integrated therein and an indenter for nano- and micro-scale indentation of a tissue. The biochip is formed with an array of micro-sensors, for example, electromechanical micro-sensors integrated on a substrate of the biochip. A temperature microsensor maybe additionally formed, for example, on the tip of the indenter to measure thermal characteristics of the tissue specimen heated by the micro-heater fabricated on the biochip. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/631275 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/68 (20130101) A61B 5/72 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 21/6458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792088 | Muratori et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Old Dominion University Research Foundation (Norfolk, Virginia) |
| ASSIGNEE(S) | Old Dominion University Research Foundation (Norfolk, Virginia) |
| INVENTOR(S) | Claudia Muratori (Virginia Beach, Virginia); Andrei G. Pakhomov (Norfolk, Virginia); Olga N. Pakhomova (Norfolk, Virginia) |
| ABSTRACT | The methods disclosed herein are directed towards improving ablation efficiency associated with applying nanosecond electric pulses (nsEP) to tissue. In particular, applying nsEP to tissue can open pores in the cellular membranes of the tissue. These pores can be kept open longer by cooling the tissue. The combined application of nsEP and the cooling of tissue may have synergistic effects on triggering apoptosis of cells in the tissue. This allows for numerous practical benefits associated with nsEP-based tissue ablation to be realized. For instance, nsEP of lower pulse strength or lower numbers of pulses to be used, which can be provided by smaller pulse generators operating on less power. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789727 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/02 (20130101) A61B 18/1206 (20130101) Original (OR) Class A61B 18/1477 (20130101) A61B 2018/00011 (20130101) A61B 2018/143 (20130101) A61B 2018/00577 (20130101) A61B 2018/00702 (20130101) A61B 2018/00726 (20130101) A61B 2018/00761 (20130101) A61B 2018/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792145 | Birla |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravi K. Birla (Sugar Land, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Ravi K. Birla (Sugar Land, Texas) |
| ABSTRACT | In some embodiments, the present disclosure pertains to a method of fabricating an artificial heart muscle (AHM) patch. In some embodiments, the method includes obtaining and/or isolating cells from a subject. In some embodiments, the cells are primary cardiac cells. In some embodiments, the method further includes forming a scaffold. In some embodiments, the method includes seeding the cells in the fibrin gel scaffold. In some embodiments, the method includes culturing the cells seeded in the fibrin gel scaffold under conditions appropriate for the formation of an artificial heart muscle (AHM) patch. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 15/725812 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/225 (20130101) A61L 27/3604 (20130101) A61L 27/3826 (20130101) A61L 27/3834 (20130101) A61L 2430/20 (20130101) A61L 2430/40 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/12 (20130101) A61M 1/122 (20140204) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2533/56 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792170 | Gregg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (Austin, Texas) |
| INVENTOR(S) | Robert D. Gregg (Allen, Texas); David Quintero (Fort Worth, Texas); Anne E. Martin (Dallas, Texas); Darío J. Villarreal Suárez (Farmers Branch, Texas) |
| ABSTRACT | Systems and methods for prosthetic device control with a unified virtual constraint that controls an entire gait cycle of the prosthetic device. |
| FILED | Thursday, February 11, 2016 |
| APPL NO | 15/550556 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/60 (20130101) A61F 2/68 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/7615 (20130101) A61F 2002/7645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792210 | Goldfarb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Franklin, Tennessee); Ryan J. Farris (Nashville, Tennessee); Hugo A. Quintero (Irvine, California) |
| ABSTRACT | A apparatus includes an a exoskeleton system with a plurality of sensors for generating signals indicating a current motion and a current arrangement of at least the exoskeleton system, a hip segment, and at least one lower limb. The lower limb includes thigh and shank segments for coupling to a lateral surface of a user's leg. The thigh segment includes a first powered joint coupling the thigh segment to the hip segment, a second powered joint coupling the thigh segment to the shank segment, and a controller coupled to the sensors, the first powered joint, and the second powered joint. The controller is configured for determining a current state of the exoskeleton system and a current intent of the user based on the signals and generating control signals for the first and second powered joints based on the current state and the current intent. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627959 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/14 (20130101) A61G 7/109 (20130101) A61G 7/1017 (20130101) A61G 7/1096 (20130101) A61G 2203/36 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0262 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 3/02 (20130101) A61H 3/04 (20130101) A61H 2201/10 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/1463 (20130101) A61H 2201/1628 (20130101) A61H 2201/1676 (20130101) A61H 2201/5005 (20130101) A61H 2201/5007 (20130101) A61H 2201/5069 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0452 (20130101) A61N 1/36003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792251 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); EXICURE, INC. (Skokie, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); EXICURE, INC. (Skokie, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Sonbinh T. Nguyen (Evanston, Illinois); Resham Singh Banga (Chicago, Illinois); Natalia Chernyak (Evanston, Illinois); Sergei Gryaznov (San Mateo, California); Aleksandar Radovic-Moreno (Evanston, Illinois); Christopher Mader (Cambridge, Massachusetts) |
| ABSTRACT | Liposomes termed as small unilamellar vesicles (SUVs), can be synthesized in the 20-50 nm size range, but encounter challenges such as instability and aggregation leading to inter-particle fusion. This limits their use as a therapeutic delivery agent. Increasing the surface negative charge of SUVs, via the attachment of anionic entities such as DNA/RNA, increases the colloidal stability of these vesicles. Additionally, the dense spherical arrangement and radial orientation of nucleic acids exhibits unique chemical and biological properties, unlike their linear counterparts. These liposomal particles, are non-toxic and though anionic, can efficiently enter cells without the aid of ancillary cationic transfection agents in a non-immunogenic fashion. These exceptional properties allow their use as delivery agents for gene regulation in different therapies and offer an alternative platform to metal core spherical nucleic acids. |
| FILED | Tuesday, January 08, 2019 |
| APPL NO | 16/242704 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1271 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792274 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jing Chen (Atlanta, Georgia); Jack Arbiser (Atlanta, Georgia); Brian Pollack (Decatur, Georgia); Siyuan Xia (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to methods of managing or treating cancer with agents that lower circulating acetoacetate levels, such as hypolipidemic agents, or other agents that antagonize acetoacetate-BRAF V600 mutant binding to attenuate BRAF V600 mutant tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of an agent to a subject in need thereof, wherein the agent is dehydroacetic acid, derivative, prodrug, or salt thereof. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386763 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792284 | Lowe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Scott W. Lowe (New York, New York); Neal Rosen (New York, New York); Eusebio Manchado-Robles (Basel, Switzerland); Susann Weissmueller (Basel, Switzerland) |
| ABSTRACT | The use of mitogen activated kinase inhibition therapy in combination with receptor tyrosine kinase therapy for the treatment of cancer is described. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/550432 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/5025 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Peptides C07K 16/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/10001 (20130101) C12Y 207/12002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/71 (20130101) G01N 2333/912 (20130101) G01N 2440/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792327 | Stupp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Bo Timmy Bjorn Fyrner (Linkoping, Sweden); Sung Soo Lee (Chicago, Illinois) |
| ABSTRACT | Provided herein are glycosylated peptide amphiphiles (GPAs), supramolecular glyconanostructures assembled therefrom, and methods of use thereof. In particular, provided herein are glycosaminoglycan (GAG) mimetic peptide amphiphiles (PAs) and supramolecular GAG mimetic nanostructures assembled therefrom that mimic the biological activities of GAGs, such as heparin, heparan sulfate, hyaluronic acid etc. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/566066 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) A61K 35/12 (20130101) A61K 38/14 (20130101) Original (OR) Class A61K 47/542 (20170801) A61K 47/549 (20170801) A61K 47/6907 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 2300/414 (20130101) A61L 2400/12 (20130101) Peptides C07K 9/003 (20130101) C07K 14/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792330 | Rincon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Mercedes Rincon (Burlington, Vermont); Ketki M. Hatle (Jamaica Plain, Massachusetts) |
| ABSTRACT | The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or compositions that increase metabolism in cells, tissues, organs, and/or subjects. In certain aspects the invention includes methods and/or compositions useful to decrease metabolism in cells, tissues, organs, and/or in subjects. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805534 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792332 | Fikrig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut); Howard Hughes Medical Institute (Chevy Chase, Maryland) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); Howard Hughes Medical Institute (Chevy Chase, Maryland) |
| INVENTOR(S) | Erol Fikrig (Guilford, Connecticut); Martin Heisig (Marburg, Germany); Nabil Abraham (New Haven, Connecticut); Girish Neelakanta (Norfolk, Virginia) |
| ABSTRACT | As microbial drug-resistance increases, there is a critical need for new classes of compounds to combat infectious diseases. The Ixodes scapularis tick antifreeze glycoprotein, IAFGP, functions as an anti-infective agent against diverse bacteria including methicillin-resistant Staphylococcus aureus. Recombinant IAFGP and a peptide, P1, described herein and derived from this protein, bind to microbes and alter biofilm formation. Transgenic iafgp-expressing flies and mice challenged with bacteria, as well as wild-type animals administered IAFGP or P1, were resistant to infection, septic shock, or biofilm development on implanted biomaterials. Antifreeze protein controls bacterial infection and present new therapeutic strategies to counter pathogens. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123291 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/7036 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 38/14 (20130101) A61K 38/14 (20130101) A61K 38/1767 (20130101) Original (OR) Class A61K 38/1767 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) A61L 15/32 (20130101) A61L 15/44 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2202/24 (20130101) A61L 2300/404 (20130101) A61L 2300/606 (20130101) A61L 2420/02 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792340 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (Chungju-si, Chungcheongbuk-do, South Korea) |
| ASSIGNEE(S) | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (Chungju-si, Chungcheon, South Korea) |
| INVENTOR(S) | Yeong Min Park (Seoul, South Korea); In Duk Jung (Cheongju-si, South Korea); Seung Jun Lee (Yeongju-si, South Korea) |
| ABSTRACT | Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/563795 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/10 (20200101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/17 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/98 (20130101) A61K 35/66 (20130101) A61K 38/45 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Enzymes C12Y 207/04003 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792348 | Pease |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Larry R. Pease (Rochester, Minnesota) |
| ABSTRACT | Materials and methods for identifying and using MEW molecule variants for activating self-reactive T cells in a peptide-specific manner, and their use to focus autoimmune cellular responses against diseases such as cancers and persisting viral infections, are described. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/135832 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/0008 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/572 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/70539 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/56977 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792349 | Jaffee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Elizabeth Marion Jaffee (Lutherville, Maryland); Lanqing Huang (Ellicott City, Maryland); Lei Zheng (Ellicott City, Maryland) |
| ABSTRACT | Compositions for the treatment of cancer include an allogeneic granulocyte-macrophage colony stimulating factor (GM-CSF)-secreting tumor cell vaccine and an anti-galectin-3 antibody. Increased titers of anti-galectin-3 antibodies were correlated with clinical outcome. |
| FILED | Monday, May 09, 2016 |
| APPL NO | 15/149598 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/193 (20130101) A61K 39/0005 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2039/575 (20130101) Peptides C07K 16/18 (20130101) C07K 16/303 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/6893 (20130101) G01N 2333/4724 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792359 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Infectious Disease Research Institute (Seattle, Washington) |
| ASSIGNEE(S) | Infectious Disease Research Institute (Seattle, Washington) |
| INVENTOR(S) | Steven G. Reed (Bellevue, Washington); Darrick Carter (Seattle, Washington) |
| ABSTRACT | Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glycopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875517 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 39/04 (20130101) A61K 39/008 (20130101) A61K 39/0011 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 45/06 (20130101) A61K 2039/55511 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/41 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/396 (20180101) Y02A 50/491 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792366 | Ho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Chien Ho (Pittsburgh, Pennsylvania); Li Liu (Pittsburgh, Pennsylvania); Qing Ye (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are methods for reducing clearance of nanotherapeutic agents from a subject, wherein the methods comprise administering a nutrition supplement to the subject prior to administration of the nanotherapeutic agent in the treatment of a disease. Methods for improving the bioavailability of the nanotherapeutic agent, methods of reducing the toxicity of the nanotherapeutic agent, and kits comprising the nutrition supplement and nanotherapeutic agent are also provided. |
| FILED | Thursday, February 18, 2016 |
| APPL NO | 15/552119 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/30 (20160801) A23L 33/115 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/107 (20130101) A61K 9/5161 (20130101) A61K 31/282 (20130101) A61K 47/44 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792374 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Da Sun (Cleveland, Ohio) |
| ABSTRACT | A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or includes a polymer, a targeting group, or a detectable moiety, and at least one of R4 and R5 includes a targeting group that targets and/or binds to a retinal or visual protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/767119 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 48/0033 (20130101) Original (OR) Class A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Heterocyclic Compounds C07D 211/88 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792375 | Heller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Richard Heller (Norfolk, Virginia); Kenneth E. Ugen (Tampa, Florida) |
| ABSTRACT | A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently administering at least one high voltage, short duration pulse to the tumor. The electroporation pulses may be administered at al least 700 V/cm for a duration of less than 1 millisecond. The intratumor treatments with electroporation may be administered in at least a two-treatment protocol with the time between treatments being about 7 days. The intratumor treatments with electroporation may be administered in a three-treatment protocol with a time of four days between the first and second treatments and a time of three days between the second and third treatments. It was found that the intratumor treatments using electroporation not only resulted in tumor regression but also induced an immune memory response which prevented the formation of new tumors. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/208144 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 38/2086 (20130101) A61K 48/005 (20130101) Original (OR) Class A61K 48/0083 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Peptides C07K 14/70532 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792377 | Uddin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jashim Uddin (Nashville, Tennessee); Brenda C. Crews (Franklin, Tennessee); Lawrence J. Marnett (Nashville, Tennessee) |
| ABSTRACT | A compound, a method of imaging a cell, and a method of detecting a cancer, an inflammatory disease, or a neoplastic disease are provided. The compound includes a nitroxide derivative of a fluorophore that is activatable upon exposure to free radicals. The method of imaging a cell includes contacting the cell with an activatable nitroxide derivative of a fluorophore. The method of detecting a cancer, an inflammatory disease, or a neoplastic disease includes administering an activatable nitroxide derivative of a fluorophore and then imaging one or more cells contacted with the compound. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944735 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0041 (20130101) Original (OR) Class A61K 49/0052 (20130101) Heterocyclic Compounds C07D 491/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792396 | Kheradvar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Arash Kheradvar (Irvine, California); Ramin Zareian (Irvine, California) |
| ABSTRACT | A hybrid tissue engineered heart valve leaflet including a polyurethane core, such as a polycarbonate-based thermoplastic polyurethane like carbothane. The polyurethane core is enclosed within one or more layer of a patient's cells and collagen. Also disclosed are hybrid tissue engineered heart valves, including a frame; and at least two leaflets attached thereto in a configuration of a heart valve, wherein the leaflets are hybrid tissue engineered heart valve leaflets, and methods of making a hybrid tissue engineered heart valve for deployment in a patient. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/198116 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/06 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3808 (20130101) Original (OR) Class A61L 27/3826 (20130101) A61L 2430/20 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792410 | Nyberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Scott L. Nyberg (Rochester, Minnesota); Stephen M. Corner (Rochester, Minnesota); Bruce Amiot (Coon Rapids, Minnesota) |
| ABSTRACT | This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170549 |
| ART UNIT | 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3472 (20130101) Original (OR) Class A61M 1/3479 (20140204) A61M 1/3486 (20140204) A61M 1/3489 (20140204) A61M 2205/103 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) C12M 25/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792518 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Taehwa Lee (Palo Alto, California); Juergen K. Willmann (Stanford, California); Jeremy Joseph Dahl (Palo Alto, California) |
| ABSTRACT | A passive cavitation mapping method is provided that includes capturing a channel signal from at least one ultrasound transducer in an array of ultrasound transducers, isolating a cavitation signal in the channel signal, time-gating the channel signal about the cavitation signal, computing a time-delay between neighboring the cavitation signals in adjacent the channel signals, computing a modified parabolic fit to the square of the arrival times, where the modified parabolic fit includes a coordinate transformation using an x location of a leading edge of wavefronts of the cavitation signal and a maximum arrival time of the cavitation signal, extracting a location of a cavitation signal source at point (x, z) in the coordinate transformation, computing a cavitation magnitude for each non-eliminated cavitation signal, creating a passive cavitation map by convolving the cavitation magnitude and the source location with an uncertainty function, and using the cavitation map for therapeutic ultrasound applications. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/027696 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/085 (20130101) A61B 8/481 (20130101) A61B 8/5207 (20130101) A61B 8/5269 (20130101) A61B 2017/00106 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) A61N 2007/0065 (20130101) A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792612 | Corcoran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | Robert C. Corcoran (Laramie, Wyoming); Kaspars Krutkramelis (Laramie, Wyoming); Rodolfo A. Monterroso (Laramie, Wyoming) |
| ABSTRACT | This invention relates to methods and compositions for removing contaminants from fluids, for example, the removal of mercury contaminants by oxidation. The compositions and methods provided herein are robust and accomplish efficient removal of contaminants from fluid streams without the need for relatively expensive activated carbon. In addition, the methods and compositions of the present invention do not pose risks to the safety of workers through the injection of highly toxic, highly corrosive elemental bromine to directly oxidize the mercury. The compositions and methods of the present invention are versatile and apply to a wide range of contaminants including, but not limited to, mercury, lead, cadmium, thallium, and hydrogen sulfides. Further, the compositions and methods contained herein are capable of efficient contaminant removal over a wide range of temperatures and pressures. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/355121 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/50 (20130101) B01D 53/52 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 53/83 (20130101) B01D 53/565 (20130101) B01D 2251/108 (20130101) B01D 2253/25 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/3236 (20130101) Removal or Treatment of Combustion Products or Combustion Residues; Flues F23J 2215/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792656 | Beebe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); David J. Guckenberger, Jr. (Oconomowoc, Wisconsin) |
| ABSTRACT | A non-displasive pipette is provided. The non-displasive pipette is configured for connection to a tip having a fluid therein. The tip includes an orifice to allow for the discharge of the fluid therefrom. The non-displasive pipette includes a body defining a chamber therethrough and having first and second opposite ends. The second end of the body is configured for connection to the tip. A plunger is slidably received in the chamber at the first end of the body. The plunger is moveable in the chamber between an extended position and a discharge position wherein the fluid is urged from tip through the orifice. An air discharge arrangement is configured to allow air from the chamber to escape therefrom and to maintain the fluid in the tip in response to connection of the second end of the body to the tip. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376625 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0217 (20130101) Original (OR) Class B01L 3/0275 (20130101) B01L 2200/16 (20130101) B01L 2200/0684 (20130101) B01L 2200/0689 (20130101) B01L 2300/0832 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793514 | Manning et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | H. Charles Manning (Franklin, Tennessee); Michael Schulte (Nashville, Tennessee) |
| ABSTRACT | The present disclosure provides compounds of formula: wherein R1, R2, and n are defined as set forth in the specification, and related aminobutanoic acids. The present disclosure also provides compositions comprising these compounds and methods for modulating ASCT2 function in a patient in need thereof. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/435169 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 229/26 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/16 (20130101) C07D 211/60 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793525 | Njar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Vincent Njar (Glen Burnie, Maryland); Hannah Mbatia (Germantown, Maryland); Vidya Ramamurthy (Baltimore, Maryland); Senthilmurugan Ramalingam (Baltimore, Maryland) |
| ABSTRACT | The synthesis and in vitro and in vivo anti-breast and anti-prostate cancers activities of novel C-4 heteroaryl 13-cis retinamides that modulate Mnk-eIF4E and AR signaling are discussed. In both breast and prostate cancer cell lines, these compounds induce Mnk1/2 degradation to substantially suppress eIF4E phosphorylation. In prostate cancer cells, the compounds induce degradation of both full-length androgen receptor (fAR) and splice variant AR (AR-V7) to inhibit AR transcriptional activity. The consequences of these multiple activities resulted in inhibition of cell growth and migration and induction of apoptosis. Finally and importantly, the compounds demonstrate strong in vitro and in vivo anti-breast and anti-prostate cancer activities, with no apparent host toxicities. |
| FILED | Wednesday, November 18, 2015 |
| APPL NO | 15/528317 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/203 (20130101) A61K 31/215 (20130101) A61K 31/505 (20130101) A61K 31/4164 (20130101) A61K 31/4406 (20130101) A61K 31/4409 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 403/20 (20130101) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 213/55 (20130101) C07D 213/56 (20130101) C07D 233/56 (20130101) Original (OR) Class C07D 239/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793526 | Cai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jianfeng Cai (Tampa, Florida); Ma Su (Tampa, Florida); Alekhya Nimmagadda (Tampa, Florida); Peng Teng (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Jianfeng Cai (Tampa, Florida); Ma Su (Tampa, Florida); Alekhya Nimmagadda (Tampa, Florida); Peng Teng (Tampa, Florida) |
| ABSTRACT | The present disclosure provides compositions including a hydantoin derivative compound, pharmaceutical compositions including a hydantoin derivative compound, methods of treatment of a condition (e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540556 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4166 (20130101) Heterocyclic Compounds C07D 233/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793544 | Yarravarapu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nageswari Yarravarapu (Dallas, Texas); Chuo Chen (Dallas, Texas); Lawrence Lum (Dallas, Texas); Lin You (Dallas, Texas); Chengwei Zhang (Dallas, Texas); Xiaolei Wang (Dallas, Texas); Lishu Zhang (Dallas, Texas) |
| ABSTRACT | The present disclosure provides compounds that may be useful for inhibiting Wnt pathway comprising compounds of the formula: (Ia) or (Ib) wherein the variables are as defined herein. In some aspects, the compounds may be used to inhibit the Wnt pathway and used to treat cancer, myocardial infarction, osteopetrosis, or used in the maturation of a precursor cell to a mature cell. Also provided herein in are pharmaceutical compositions of the compounds described herein. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 16/330050 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 31/506 (20130101) A61K 31/4192 (20130101) A61K 31/4439 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 255/02 (20130101) C07D 401/12 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 409/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793567 | Fuller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodin Therapeutics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided are compounds of the formula and pharmaceutically acceptable salts and composition thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g. HDAC2). |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 16/477466 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793573 | Gangjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania); Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania); Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania); Larry H. Matherly (Novi, Michigan) |
| ABSTRACT | A compound of the Formula I and optionally a pharmaceutically acceptable salt thereof is provided: Formula I, wherein, R is one selected from the group consisting of H and CH3; n is an integer ranging from 1 to 4; X is one selected from the group consisting of —CH2—, O, S, —NH—, —NHCHO—, —NHCOCH3—, and —NHCOCF3—; and Ar is one selected from the group consisting of (a) 1,4-phenyl, (b) 2′-fluoro-1,4-phenyl, and (c) 2,5-thienyl. Methods of treating a patient having cancer, targeting mitochondrial metabolism, and targeting SHMT2 and MTHFD2 using the compounds of this invention are disclosed. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/118007 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793590 | Van Arnam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellow of Harvard College (Cambridge, Massachusetts); Wisconsin Alumni Research Foundation (Madison, Wisconsin); Universidad de Costa Rica (San José, Costa Rica) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Wisconsin Alumni Research Foundation (Madison, Wisconsin); Universidad de Costa Rica (San José, Costa Rica) |
| INVENTOR(S) | Ethan Van Arnam (Somerville, Massachusetts); Clarissa Sit (Brookline, Massachusetts); Antonio Ruzzini (Brookline, Massachusetts); Jon Clardy (Jamaica Plain, Massachusetts); Cameron Currie (Madison, Wisconsin); Adrian Alberto Pinto-Tomas (San José, Costa Rica) |
| ABSTRACT | Compounds of formula (I) or formula (II), compositions and methods useful for treating and/or preventing a fungal infections are provided. wherein the substituents are as defined in the appended claims. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 16/305965 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793595 | Morse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | David L. Morse (Tampa, Florida); Josef Vagner (Tucson, Arizona); Mark McLaughlin (Tampa, Florida); Robert Gillies (Tampa, Florida); Amanda Huynh (Land O Lakes, Florida); Michael Doligalski (Lutz, Florida) |
| ABSTRACT | Disclosed are monoacylated Toll-like receptor 2 ligands which can be used in both the development of targeted agents for the imaging and treatment of pancreatic cancer as well as other cancers, and as an adjuvant for cancer immunotherapy. The monoacylated compounds disclosed herein have a higher binding affinity for TLR2 relative to a known potent diacylated agonists, but only −½ the bioactivity. Competition of the monoacylated compound with the diacylated compound for binding TLR2 was confirmed. Hence, the reported monoacylated compounds are inhibitors/antagonists of TLR2 activation. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/150496 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0019 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) A61K 51/0497 (20130101) Peptides C07K 5/081 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793605 | Ly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Danith H. Ly (Pittsburgh, Pennsylvania); Srinivas Rapireddy (Pittsburgh, Pennsylvania); Bichismita Sahu (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362579 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793606 | Zolotukhin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida); Shannon E. Boye (Gainesville, Florida); Damien Marsic (Rockville, Maryland); Paul D. Gamlin (Birmingham, Alabama) |
| ABSTRACT | Adeno associated viral (AAV) particles are emerging as useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547532 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2320/32 (20130101) C12N 2750/14011 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793613 | Krupnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Sasha Krupnick (St. Louis, Missouri); Eric Reed Lazear (St. Louis, Missouri); Daved Henry Fremont (St. Louis, Missouri) |
| ABSTRACT | The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. |
| FILED | Tuesday, December 15, 2015 |
| APPL NO | 15/536580 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/65 (20170801) A61K 47/642 (20170801) Peptides C07K 14/005 (20130101) C07K 14/55 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2319/20 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) Technologies for Adaptation to Climate Change Y02A 50/393 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793623 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Samuel Lai (Carrboro, North Carolina); M. Gregory Forest (Chapel Hill, North Carolina); Christine Henry (Chapel Hill, North Carolina); Timothy Wessler (Durham, North Carolina); Alexander Chen (Glenville, New York); Jennifer Schiller (Chapel Hill, North Carolina); Jay Newby (Carrboro, North Carolina) |
| ABSTRACT | The presently-disclosed subject matter relates to crosslinkers, compositions, and methods for trapping a target of interest on a substrate of interest. The methods may be used to inhibit and treat pathogen infection and provide contraception. The methods may be used to trap or separate particles and other substances. The subject matter further relates to methods of identifying and preparing optimal crosslinkers and methods for manipulating targets of interest. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977432 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 16/44 (20130101) C07K 16/087 (20130101) C07K 16/1045 (20130101) C07K 16/1235 (20130101) Original (OR) Class C07K 2317/41 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/557 (20130101) G01N 33/6854 (20130101) G01N 33/54346 (20130101) G01N 33/56983 (20130101) G01N 2333/16 (20130101) G01N 2333/4725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793625 | Cao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Xu Cao (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of osteoarthritis. More specifically, the present invention provides compositions and methods useful for treating or preventing osteoarthritis. In one embodiment, a method for treating or preventing osteoarthritis in a patient comprises the step of administering to the patient a therapeutically effective amount of a transforming growth factor beta (TGF-beta) inhibitor. |
| FILED | Wednesday, May 01, 2013 |
| APPL NO | 14/397933 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/663 (20130101) A61K 31/4439 (20130101) A61K 49/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793633 | Wucherpfennig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kai W. Wucherpfennig (Brookline, Massachusetts); Bettina Franz (Orem, Utah); Kenneth F. May, Jr. (Bozeman, Montana); Glenn Dranoff (Sudbury, Massachusetts); F. Stephen Hodi (Framingham, Massachusetts); Christopher Harvey (Boston, Massachusetts) |
| ABSTRACT | The present disclosure provides, in part, compositions comprising peptides that immunospecifically bind to a defined binding partner, such as MHC class I polypeptide-related sequence A (MICA), or an epitope thereon. In some embodiments, the peptides comprise one or more complementarity determining regions relating to the complementarity regions shown in Table 1. The disclosure also provides methods of treating cancer in a subject using the compositions disclosed herein, and methods of isolating human antibodies from cancer patients following immunotherapy. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/211758 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/325 (20130101) A61K 31/365 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Peptides C07K 16/06 (20130101) C07K 16/22 (20130101) C07K 16/1282 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793823 | Shara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rapid Micro Biosystems, Inc. (Lowell, Massachusetts) |
| ASSIGNEE(S) | Rapid Micro Biosystems, Inc. (Lowell, Massachusetts) |
| INVENTOR(S) | Kate Shara (Nashua, New Hampshire); Julie Schwedock (Arlington, Massachusetts); Sommer Vogel (Lowell, Massachusetts) |
| ABSTRACT | The present invention features general-purpose microbiological growth media capable of supporting growth of microorganisms on membranes. The media contain casein digest, soybean digest, animal tissue digest, yeast extract, dextrose, a phosphate buffer, hemin, and L-cystine. The invention features an all-purpose microbiological growth media that can support the growth of anaerobes, molds, injured spores, and general aerobic bacteria to a greater extent than other media. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 15/305789 |
| ART UNIT | 1699 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/16 (20130101) C12N 1/20 (20130101) Original (OR) Class C12N 1/38 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793835 | Yan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Ziying Yan (Iowa City, Iowa); John F. Engelhardt (Iowa City, Iowa); Jianming Qiu (Overland Park, Kansas) |
| ABSTRACT | The invention provides an isolated chimeric virus comprising bocavirus capsid protein and a recombinant adeno-associated viral (AAV) genome, an isolated rBoV comprising human bocavirus capsid protein and a recombinant BoV genome, and uses therefor. For example, the chimeric virus may be employed to deliver transgenes, such as those encoding therapeutic or prophylactic gene products, to mammalian cells. |
| FILED | Monday, November 27, 2017 |
| APPL NO | 15/822956 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/23 (20130101) A61K 2039/5256 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/435 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/8645 (20130101) C12N 2750/14111 (20130101) C12N 2750/14121 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2750/14144 (20130101) C12N 2750/14145 (20130101) C12N 2750/14322 (20130101) C12N 2750/14333 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793861 | Kaspar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); LUDWIG INSTITUTE FOR CANCER RESEARCH (Zurich, Switzerland) |
| ASSIGNEE(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); LUDWIG INSTITUTE FOR CANCER RESEARCH (Zurich, Switzerland) |
| INVENTOR(S) | Brian K. Kaspar (Columbus, Ohio); Kevin Foust (Columbus, Ohio); Don W. Cleveland (La Jolla, California) |
| ABSTRACT | The present invention relates to RNA-based methods for inhibiting the expression of the superoxide dismutase 1 (SOD-1) gene. Recombinant adeno-associated viruses of the invention deliver DNAs encoding RNAs that knock down the expression of SOD-1. The methods have application in the treatment of amyotrophic lateral sclerosis. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/041381 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/7105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/0089 (20130101) C12N 15/86 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/32 (20130101) C12N 2750/14043 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 115/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793864 | Spear et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| ASSIGNEE(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| INVENTOR(S) | Mark Spear (Fairfax, Virginia); Yuntao Wu (Fairfax, Virginia) |
| ABSTRACT | In one aspect, the invention relates to methods and compositions for determining migration of a virus particle to the nucleus of a cell. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 15/389834 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) C07K 14/43595 (20130101) C07K 2319/61 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1088 (20130101) C09K 2211/1441 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/62 (20130101) Original (OR) Class C12N 2740/15023 (20130101) C12N 2740/16023 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793898 | Lal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ratneshwar Lal (La Jolla, California); Michael Taeyoung Hwang (La Jolla, California); Preston Boone Landon (Oceanside, California); Gennadi V. Glinskii (La Jolla, California); Alexander Mo (San Diego, California); Srinivasan Ramachandran (Fremont, California); Joon Lee (La Jolla, California); Brian Meckes (Evanston, Illinois) |
| ABSTRACT | Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 16/065701 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 2563/107 (20130101) C12Q 2565/525 (20130101) C12Q 2565/607 (20130101) C12Q 2565/625 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) G01N 27/125 (20130101) G01N 27/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793899 | Rao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides methods for performing an imaging method to detect a moiety associated with labeled hydroxymethylated bases in nucleic acid sequences, such as detecting a moiety associated with glucosylated 5-hydroxmethylated cytosines. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/411998 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2501/70 (20130101) C12N 2501/71 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 2521/531 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793902 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE Secretary of Health and Human Services (Atlanta, Georgia) |
| ASSIGNEE(S) | The Government of the United States of America, as Represented by the Secretary, Department of Health and Human Services, Centers for Disease Control and Prevention (Atlanta, Georgia) |
| INVENTOR(S) | Jeffrey A. Johnson (Stone Mountain, Georgia); Walid M. Heneine (Atlanta, Georgia); Jonathan T. Lipscomb (Decatur, Georgia) |
| ABSTRACT | Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding the reverse transcriptase, protease, or integrase of HIV as disclosed herein. Thus, provided in an oligonucleotide comprising any one of the nucleotide sequences set forth in SEQ ID NOS: 1-89, 96-122, and 124-141. Also provided are the oligonucleotides consisting of the nucleotides as set forth in SEQ ID NOS: 1-89, 96-122, and 124-141. Each of the disclosed oligonucleotides is a probe or a primer. Also provided are mixtures of primers and probes and for use in RT-PCR and primary PCT reactions disclosed herein. Provided are methods for the specific detection of several mutations in HIV simultaneously or sequentially. Mutations in the reverse transcriptase, protease, or integrase of HIV can be detected using the methods described herein. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/848555 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/686 (20130101) Original (OR) Class C12Q 1/703 (20130101) C12Q 1/6844 (20130101) C12Q 2600/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793903 | Flusberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | Benjamin Flusberg (Atlanta, Georgia); Stephen Turner (Seattle, Washington); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (La Honda, California) |
| ABSTRACT | Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/278835 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6837 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2525/117 (20130101) C12Q 2525/307 (20130101) C12Q 2527/113 (20130101) C12Q 2527/113 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793913 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Shizhen Emily Wang (Glendora, California); Xiwei Wu (Diamond Bar, California) |
| ABSTRACT | Provided are methods of treating breast cancer in a subject in need thereof comprising administering to the subject an effective amount of an inhibitor of miR-105 or an inhibitor of miR-122 are provided. Also provided herein are methods of determining a level of miR-105 or a level of miR-122 in a subject that has or is at risk for developing breast cancer. The method includes obtaining a biological sample from the subject and determining a level of miR-105 or a level of miR-122 or a combination thereof in the biological sample, wherein a higher level of miR-105 or miR-122 as compared to a control indicates that the subject has or is at risk of developing breast cancer. |
| FILED | Monday, March 10, 2014 |
| APPL NO | 14/203173 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793914 | Skog et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Johan Karl Olov Skog (New York, New York); Leonora Balaj (Charlestown, Massachusetts); Mikkel Noerholm (Gauting, Germany); Xandra O. Breakefield (Newton, Massachusetts) |
| ABSTRACT | Disclosed herein are methods for assaying a biological sample from a subject by analyzing components of microvesicle fractions in aid of risk, diagnosis, prognosis or monitoring of, or directing treatment of the subject for, a disease or other medical condition in the subject. Also disclosed are methods of treatment and identifying biomarkers using a microvesicle fraction of a subject. Kits, pharmaceutical compositions, and profiles related to the methods are also disclosed. |
| FILED | Monday, February 01, 2016 |
| APPL NO | 15/012111 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2563/161 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794802 | Gradinaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Viviana Gradinaru (La Canada Flintridge, California); Jennifer Treweek (Pasadena, California) |
| ABSTRACT | In various embodiments, the present application teaches methods for tissue clearing in which tissues are rendered macromolecule-permeable and optically-transparent, thereby exposing their cellular structure with intact connectivity. In some embodiments, the present application teaches ePACT, which is a protocol for enhanced tissue clearing via expansion. In some embodiments, the present application teaches visualizing a tissue that has been expanded via ePACT. |
| FILED | Wednesday, August 17, 2016 |
| APPL NO | 15/239724 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6841 (20130101) C12Q 2527/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794828 | Zhuang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Lexington, Massachusetts); Wilfred M. Bates (Gottingen, Germany); Michael J. Rust (Somerville, Massachusetts) |
| ABSTRACT | The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The entities may be immobilized relative to each other and/or to a common entity. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction limit resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA, a protein, a cell, a tissue, etc. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction limit image resolution, computer programs and techniques for sub-diffraction limit image resolution, methods for promoting sub-diffraction limit image resolution, methods for producing photoswitchable entities, and the like. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058525 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) C09K 2211/1044 (20130101) C09K 2211/1475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1475 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/582 (20130101) G01N 2015/0065 (20130101) G01N 2021/6421 (20130101) G01N 2021/6439 (20130101) G01N 2021/6441 (20130101) G01N 2201/12 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794895 | Xie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ping Xie (Needham, Massachusetts) |
| ABSTRACT | A nanopore sensor is provided, including a nanopore disposed in a support structure. A fluidic passage is disposed between a first fluidic reservoir and the nanopore to fluidically connect the first fluidic reservoir to the nanopore through the fluidic passage. The fluidic passage has a passage length that is greater than the passage width. A second fluidic reservoir is fluidically connected to the nanopore, with the nanopore providing fluidic communication between the fluidic passage the second reservoir. Electrodes are connected to impose an electrical potential difference across the nanopore. At least one electrical transduction element is disposed in the nanopore sensor with a connection to measure the electrical potential that is local to the fluidic passage. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015277 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 2300/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0867 (20130101) B01L 2300/0896 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 27/4163 (20130101) G01N 27/4473 (20130101) G01N 27/44726 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794898 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); LOYOLA UNIVERSITY CHICAGO (Maywood, Illinois) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Loyola University Chicago (Maywood, Illinois) |
| INVENTOR(S) | David D. Thomas (Minneapolis, Minnesota); Simon Joseph Gruber (Brooklyn, New York); Razvan L. Cornea (Saint Paul, Minnesota); Gregory David Gillispie (Falcon Heights, Minnesota); Kurt C. Peterson (Saint Paul, Minnesota); Seth Louis Robia (Westchester, Illinois) |
| ABSTRACT | Methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. The methods include use of a genetically engineered cell that includes a target protein. The target protein includes one or more heterologous domains. In one embodiment, a target protein includes two heterologous domains, and in another embodiment, the target protein includes a heterologous domain and the cell further includes a second protein that includes a heterologous domain. A heterologous domain may include a chromophore or an amino acid to which a fluorescent dye attaches. The fluorescence lifetime of one or more chromophore, one or more fluorescent dye, or the combination thereof, is measured after contacting the cell with a compound A difference between the fluorescence lifetime in the presence of the test compound and the fluorescence lifetime in the absence of the test compound indicates that the test compound alters the FRET of the target protein. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 14/598707 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 33/502 (20130101) Original (OR) Class G01N 33/582 (20130101) G01N 2021/6441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794901 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wei Li (Miami, Florida) |
| ASSIGNEE(S) | Wei Li (Miami, Florida) |
| INVENTOR(S) | Wei Li (Miami, Florida) |
| ABSTRACT | The present invention is directed to methods for developing novel anti-angiogenic therapies. This invention discovers secretogranin III (Scg3) not only as a novel disease-selective angiogenic factor but also as a target for anti-angiogenic therapy of vascular diseases. Inhibitors against Scg3 can treat diabetic retinopathy, wet age-related macular degeneration, retinopathy of prematurity, retinal vein occlusion, neovascular glaucoma, corneal neovascularization, and cancers. |
| FILED | Tuesday, January 02, 2018 |
| APPL NO | 15/860170 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/05 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 25/28 (20180101) A61P 27/10 (20180101) A61P 35/00 (20180101) Peptides C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/1037 (20130101) C12N 15/1037 (20130101) C12N 2310/16 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/68 (20130101) C12Q 2535/122 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) G01N 33/53 (20130101) Original (OR) Class G01N 33/6842 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794915 | Marriott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); President and Board of Trustees of Santa Clara College (Santa Clara, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); PRESIDENT AND BOARD OF TRUSTEES OF SANTA CLARA COLLEGE (Santa Clara, California) |
| INVENTOR(S) | Gerard Marriott (Palo Alto, California); Alexander Chris Hoepker (Oakland, California); Yuling Yan (Oakland, California) |
| ABSTRACT | Isolated truncated and mutated sensor proteins derived from flavoproteins that are 12-20 KDa or less, genetically encoded for detection and imaging of protein complexes having long fluorescent lifetimes that can be 4.0 ns or greater. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/946461 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/28 (20130101) C07K 14/195 (20130101) C07K 14/415 (20130101) C07K 17/02 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794925 | Chiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Bryant S. Fujimoto (Seattle, Washington); Jason E. Kreutz (Seattle, Washington) |
| ABSTRACT | Systems, methods, and devices for discretizing and analyzing fluidic samples are provided. In one aspect, a microfluidic array for discretizing a fluidic sample comprises one or more flow channels and a plurality of fluidic compartments in fluidic communication with the one or more flow channels. In another aspect, a system for discretizing and analyzing fluidic samples comprises a rotor assembly shaped to receive a microfluidic device. |
| FILED | Thursday, July 07, 2016 |
| APPL NO | 15/741462 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/502746 (20130101) B01L 7/52 (20130101) B01L 9/523 (20130101) B01L 2200/027 (20130101) B01L 2200/0673 (20130101) B01L 2300/18 (20130101) B01L 2300/0809 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/1894 (20130101) B01L 2400/0409 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1463 (20130101) G01N 21/6456 (20130101) G01N 35/04 (20130101) G01N 35/025 (20130101) G01N 35/00069 (20130101) G01N 35/1016 (20130101) Original (OR) Class G01N 2015/1006 (20130101) G01N 2035/00158 (20130101) G01N 2035/00356 (20130101) G01N 2035/00366 (20130101) G01N 2035/0449 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795037 | Olcott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RefleXion Medical, Inc. (Hayward, California) |
| ASSIGNEE(S) | RefleXion Medical, Inc. (Hayward, California) |
| INVENTOR(S) | Peter Demetri Olcott (Los Gatos, California); Matthew Francis Bieniosek (Atherton, California) |
| ABSTRACT | Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/033125 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/172 (20130101) G01T 1/208 (20130101) G01T 1/2023 (20130101) G01T 1/2985 (20130101) Original (OR) Class G01T 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795896 | Contractor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Noshir S. Contractor (Evanston, Illinois); Harshad E. Gado (Evanston, Illinois); Anup S. Sawant (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure include a system that automatically defines and assembles a group of users capable of solving a particular problem, such as problems associated with network platforms and infrastructures. The group of users are identified from user data captured while users interact within and throughout a network, such as a social network. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927721 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/248 (20190101) G06F 16/951 (20190101) G06F 16/24575 (20190101) G06F 16/24578 (20190101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 10/063112 (20130101) G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796246 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandeep Gupta (Phoenix, Arizona); Ayan Banerjee (Mesa, Arizona); Mohammad Javad Sohankar Esfahani (Tempe, Arizona); Seyed Koosha Sadeghi Oskooyee (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Sandeep Gupta (Phoenix, Arizona); Ayan Banerjee (Mesa, Arizona); Mohammad Javad Sohankar Esfahani (Tempe, Arizona); Seyed Koosha Sadeghi Oskooyee (Tempe, Arizona) |
| ABSTRACT | A Brain-Mobile Interface (BMoI) system is provided. A control circuit is configured to execute a predictive model to generate a defined number of predicted signal features in future time based on a number of signal features extracted from a first type sensory data (e.g., electroencephalogram (EEG) data). A predicted future mental state(s) can thus be generated based on the number of predicted signal features and used to trigger a corresponding action(s) in a BMoI application(s). In a non-limiting example, a second type sensory data (e.g., electrocardiogram (ECG) data) can be used to improve accuracy of the predictive model. By using the predicted signal features to generate the predicted future mental state(s) to control the BMoI application(s), it is possible to duty-cycle the BMoI system to help reduce power consumption and processing latency, thus allowing the BMoI application(s) to operate in real-time with improved accuracy and power consumption. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 15/857794 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Wireless Communication Networks H04W 40/24 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796692 | Cantu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marcos A. Cantu (Rancho Viejo, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcos A. Cantu (Rancho Viejo, Texas) |
| ABSTRACT | An assistive listening device includes a set of microphones including an array arranged into pairs about a nominal listening axis with respective distinct intra-pair microphone spacings, and a pair of ear-worn loudspeakers. Audio circuitry performs arrayed-microphone short-time target cancellation processing including (1) applying short-time frequency transforms to convert time-domain audio input signals into frequency-domain signals for every short-time analysis frame, (2) calculating ratio masks from the frequency-domain signals of respective microphone pairs, wherein the calculation of a ratio mask includes a frequency domain subtraction of signal values of a microphone pair, (3) calculating a global ratio mask from the plurality of ratio masks, and (4) applying the global ratio mask, and inverse short-time frequency transforms, to selected ones of the frequency-domain signals, thereby generating audio output signals for driving the loudspeakers. The circuitry and processing may also be realized in a machine hearing device executing a human-computer interface application. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514669 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/17823 (20180101) G10K 11/17873 (20180101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/20 (20130101) Original (OR) Class G10L 15/22 (20130101) G10L 15/1815 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/04 (20130101) H04R 1/406 (20130101) H04R 3/005 (20130101) H04R 5/027 (20130101) H04R 2201/401 (20130101) H04R 2499/11 (20130101) Stereophonic Systems H04S 7/30 (20130101) H04S 2400/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796715 | Berisha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Visar Berisha (Tempe, Arizona); Ming Tu (Tempe, Arizona); Alan Wisler (Plano, Texas); Julie Liss (Scottsdale, Arizona) |
| ABSTRACT | Systems and methods use patient speech samples as inputs, use subjective multi-point ratings by speech-language pathologists of multiple perceptual dimensions of patient speech samples as further inputs, and extract laboratory-implemented features from the patient speech samples. A predictive software model learns the relationship between speech acoustics and the subjective ratings of such speech obtained from speech-language pathologists, and is configured to apply this information to evaluate new speech samples. Outputs may include objective evaluation of the plurality of perceptual dimensions for new speech samples and/or evaluation of disease onset, disease progression, or disease treatment efficacy for a condition involving dysarthria as a symptom, utilizing the new speech samples. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/693699 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/48 (20130101) A61B 5/4803 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 15/16 (20130101) G10L 15/22 (20130101) G10L 25/51 (20130101) G10L 25/60 (20130101) G10L 25/66 (20130101) Original (OR) Class G10L 25/78 (20130101) G10L 25/90 (20130101) G10L 2015/022 (20130101) G10L 2015/025 (20130101) G10L 2015/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796804 | Baronov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Etiometry Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Etiometry, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dimitar V. Baronov (Boston, Massachusetts); Evan J. Butler (New Haven, Connecticut); Jesse M. Lock (Winchester, Massachusetts); Michael F. McManus (Halifax, Massachusetts) |
| ABSTRACT | A risk-based patient monitoring system for critical care patients combines data from multiple sources to assess the current and the future risks to the patient, thereby enabling providers to review a current patient risk profile and to continuously track a clinical trajectory. A physiology observer module in the system utilizes multiple measurements to estimate Probability Density Functions (PDF) of a number of Internal State Variables (ISVs) that describe a components of the physiology relevant to the patient treatment and condition. A clinical trajectory interpreter module in the system utilizes the estimated PDFs of ISVs to identify under which probable patient states the patient can be currently categorized and assign a probability value that the patient will be in each of the identified states. The combination of patient states and their probabilities is defined as the clinical risk to the patient. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113486 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797926 | Walk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); Technische Universität Berlin (Berlin, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Technische Universität Berlin (Berlin, Germany) |
| INVENTOR(S) | Philipp Walk (Pasadena, California); Babak Hassibi (San Marino, California); Peter Jung (Berlin, Germany) |
| ABSTRACT | Systems and methods for transmitting data using various Modulation on Zeros schemes are described. In many embodiments, a communication system is utilized that includes a transmitter having a modulator that modulates a plurality of information bits to encode the bits in the zeros of the z-transform of a discrete-time baseband signal. In addition, the communication system includes a receiver having a decoder configured to decode a plurality of bits of information from the samples of a received signal by: determining a plurality of zeros of a z-transform of a received discrete-time baseband signal based upon samples from a received continuous-time signal, identifying zeros that encode the plurality of information bits, and outputting a plurality of decoded information bits based upon the identified zeros. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/260059 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Multiplex Communication H04J 11/00 (20130101) H04J 2011/0096 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0204 (20130101) H04L 27/2627 (20130101) Original (OR) Class H04L 27/2639 (20130101) H04L 27/2649 (20130101) H04L 27/2663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10791722 | Hay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Bruce A. Hay (Encino, California); Omar S. Akbari (Pasadena, California); Anna B. Buchman (Pasadena, California) |
| ABSTRACT | Embodiments provided herein relate to systems for synthetically-engineered reciprocal chromosomal translocation for gene insertion into a population of organisms such as insects. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164452 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0339 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2227/706 (20130101) A01K 2267/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791731 | Chapman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Michael P. Chapman (Denver, Colorado); Ernest Moore (Denver, Colorado) |
| ABSTRACT | Systems for controlled freezing, storing and thawing a biological material in a bag and supporting apparatus. The systems are adapted to receive the biological material therein for freezing, storing, transporting and rapid thawing immediately prior to administration to a patient in need of the biological material. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/580980 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0263 (20130101) Original (OR) Class A01N 1/0273 (20130101) A01N 1/0284 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/025 (20130101) A61M 1/0277 (20140204) A61M 1/0281 (20130101) A61M 2205/366 (20130101) A61M 2205/3368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791779 | Carter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | David J. Carter (Concord, Massachusetts); Tirunelveli S. Sriram (Acton, Massachusetts); Parshant Kumar (Stoneham, Massachusetts); Clayton Morris (Norfolk, Massachusetts); William W. McFarland (Waltham, Massachusetts); Eugene H. Cook (Acton, Massachusetts); John LeBlanc (North Andover, Massachusetts); Alla Gimbel (Medford, Massachusetts) |
| ABSTRACT | A mold for casting a micro-scale structure includes an upper surface including a first cavity having a first depth. A negative pattern for an array of micro-scale structures is defined in a surface of the first cavity. The mold includes at least one second cavity having a second depth defined in the cavity outside of the negative pattern for the array of micro-scale structures. The at least one second cavity defines a negative pattern for a standoff of the micro-scale structure. A fabric retaining frame is disposed in the first cavity. |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 15/534907 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 19/01564 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/58 (20130101) B29C 33/424 (20130101) B29C 33/3842 (20130101) B29C 37/0053 (20130101) B29C 39/10 (20130101) B29C 39/026 (20130101) B29C 39/26 (20130101) B29C 45/372 (20130101) B29C 2059/023 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0067 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/0097 (20130101) B29K 2863/00 (20130101) B29K 2891/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/4864 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792088 | Muratori et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Old Dominion University Research Foundation (Norfolk, Virginia) |
| ASSIGNEE(S) | Old Dominion University Research Foundation (Norfolk, Virginia) |
| INVENTOR(S) | Claudia Muratori (Virginia Beach, Virginia); Andrei G. Pakhomov (Norfolk, Virginia); Olga N. Pakhomova (Norfolk, Virginia) |
| ABSTRACT | The methods disclosed herein are directed towards improving ablation efficiency associated with applying nanosecond electric pulses (nsEP) to tissue. In particular, applying nsEP to tissue can open pores in the cellular membranes of the tissue. These pores can be kept open longer by cooling the tissue. The combined application of nsEP and the cooling of tissue may have synergistic effects on triggering apoptosis of cells in the tissue. This allows for numerous practical benefits associated with nsEP-based tissue ablation to be realized. For instance, nsEP of lower pulse strength or lower numbers of pulses to be used, which can be provided by smaller pulse generators operating on less power. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789727 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/02 (20130101) A61B 18/1206 (20130101) Original (OR) Class A61B 18/1477 (20130101) A61B 2018/00011 (20130101) A61B 2018/143 (20130101) A61B 2018/00577 (20130101) A61B 2018/00702 (20130101) A61B 2018/00726 (20130101) A61B 2018/00761 (20130101) A61B 2018/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792251 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); EXICURE, INC. (Skokie, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); EXICURE, INC. (Skokie, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Sonbinh T. Nguyen (Evanston, Illinois); Resham Singh Banga (Chicago, Illinois); Natalia Chernyak (Evanston, Illinois); Sergei Gryaznov (San Mateo, California); Aleksandar Radovic-Moreno (Evanston, Illinois); Christopher Mader (Cambridge, Massachusetts) |
| ABSTRACT | Liposomes termed as small unilamellar vesicles (SUVs), can be synthesized in the 20-50 nm size range, but encounter challenges such as instability and aggregation leading to inter-particle fusion. This limits their use as a therapeutic delivery agent. Increasing the surface negative charge of SUVs, via the attachment of anionic entities such as DNA/RNA, increases the colloidal stability of these vesicles. Additionally, the dense spherical arrangement and radial orientation of nucleic acids exhibits unique chemical and biological properties, unlike their linear counterparts. These liposomal particles, are non-toxic and though anionic, can efficiently enter cells without the aid of ancillary cationic transfection agents in a non-immunogenic fashion. These exceptional properties allow their use as delivery agents for gene regulation in different therapies and offer an alternative platform to metal core spherical nucleic acids. |
| FILED | Tuesday, January 08, 2019 |
| APPL NO | 16/242704 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1271 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792268 | D'Agostino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Dominic Paul D'Agostino (Tampa, Florida); Shannon Kesl (Long Beach, California) |
| ABSTRACT | The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM) without need for dietary restriction. The effects of ketogenic agents were tested on blood glucose, ketones, and lipids with a 28-day dose escalation study in male Sprague-Dawley rats: R,S-1,3-Butandiol (BD), acetoacetate ketone ester (KE), and control (H2O) (n≥8). Days 1-28, rats received a daily 5 g/kg intragastric gavage, based on previous toxicology studies. Once weekly, whole blood samples (10 μl) were acquired for analysis of glucose and βHB at 0, 0.5, 1, 4, 8, and 12 hours after test substance administration, or until βHB returned to baseline. At day 1 and 28, 10 μL of whole blood were collected to measure triglycerides, total cholesterol, and HDL concentration. Significant elevation of blood ketone was observed with a significant inverse relationship with blood glucose for the duration of the experiment. There were no significant changes in the lipid panel for any of the substances. There were significant reductions in body weight when animals were treated with either BD or KE as compared to control. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 15/451891 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/225 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 31/207 (20130101) C07C 69/16 (20130101) C07C 69/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792353 | Vedvick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas S. Vedvick (Cambridge, Massachusetts); Bryan Steadman (Cambridge, Massachusetts); Charles Richardson (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); Charles R. Petrie (Cambridge, Massachusetts) |
| ABSTRACT | Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/213297 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Peptides C07K 1/18 (20130101) C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) C12N 2770/16051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792639 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Klavs F. Jensen (Lexington, Massachusetts); Dale Arlington Thomas, III (Hampden, Maine) |
| ABSTRACT | Aspects of the present disclosure relate to reconfigurable chemical synthesis systems and related components and methods. In one aspect, a fluidic system comprises a plurality of fluid outlets, a plurality of fluid inlets, a plurality of tensioners, and a plurality of flexible conduits associated with the plurality of tensioners, wherein at least one flexible conduit of the plurality of flexible conduits is configured to fluidically connect a fluid outlet of the plurality of fluid outlets and a fluid inlet of the plurality of fluid inlets. Another aspect relates to a method in which ends of a plurality of flexible conduits are physically moved along paths, one after the other, prior to flowing material through the flexible conduits, after which the ends of the flexible conduits are again physically moved. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953983 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/004 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00788 (20130101) B01J 2219/00795 (20130101) B01J 2219/00889 (20130101) B01J 2219/00894 (20130101) B01J 2219/00905 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/561 (20130101) B01L 2200/026 (20130101) B01L 2200/028 (20130101) B01L 2400/0487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792660 | Ndao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuTech Ventures, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sidy Ndao (Lincoln, Nebraska); George Gogos (Lincoln, Nebraska); Dennis Alexander (Lincoln, Nebraska); Troy Anderson (Omaha, Nebraska); Craig Zuhlke (Lincoln, Nebraska) |
| ABSTRACT | Systems and methods are described for propelling a liquid droplet in a Leidenfrost state. A microfluidic device embodiment includes, but is not limited to, a solid structure having a patterned surface, the patterned surface including at least a first patterned region having a first Leidenfrost temperature with respect to a fluid material and a second patterned region having a second Leidenfrost temperature with respect to the fluid, the first patterned region adjacent to the second patterned region, the first patterned region defining a path over which a droplet of the fluid is configured to travel in a Leidenfrost state. |
| FILED | Tuesday, January 13, 2015 |
| APPL NO | 14/595487 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502792 (20130101) Original (OR) Class B01L 2300/1805 (20130101) B01L 2400/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792807 | Lessing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Joshua Aaron Lessing (Cambridge, Massachusetts); Ramses V. Martinez (Madrid, Spain); Alok Suryavamsee Tayi (Somerville, Massachusetts); Jason Ming Ting (Katy, Texas); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A soft robot having an integrated electrical component includes an expandable or collapsible body, the body comprising an inlet that is configured to communicate with a fluid source and a flexible strain limited layer secured to a portion of the expandable or collapsible body, wherein the strain limited layer includes at least one electrical component. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/972412 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0012 (20130101) B25J 9/142 (20130101) Original (OR) Class B25J 13/08 (20130101) B25J 15/0009 (20130101) B25J 15/12 (20130101) B25J 18/06 (20130101) B25J 19/028 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792857 | Desimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. Desimone (Monte Sereno, California); Gregory R. Robbins (Redwood City, California); Ashley R. Johnson (Coppell, Texas) |
| ABSTRACT | The invention generally relates to microneedle devices, methods of making same, pharmaceutical compositions comprising same, and methods of treating a disease comprising administering same. Specifically, the disclosed microneedle devices comprise a plurality of biocompatible microneedles having one or more of: (i) a curved, discontinuous, undercut, and/or perforated sidewall; (ii) a sidewall comprising a breakable support; and (iii) a cross-section that is non-circular and non-polygonal. The microneedles may also be tiered. Alternatively, the microneedles may be tiered. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Saturday, March 12, 2016 |
| APPL NO | 15/557003 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/150022 (20130101) A61B 5/150282 (20130101) A61B 5/150984 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Original (OR) Class B29C 64/129 (20170801) B29C 64/135 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793265 | Tayman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven K. Tayman (Alexandria, Virginia) |
| ABSTRACT | An expendable rotary wing unmanned aircraft capable of storage in a cylindrical housing includes a longitudinally extending body having an upper end and a lower end; and a pair of counter-rotating coaxial rotors each located at respective ends of longitudinally-extending body, wherein each rotor includes two or more blades, each blade rotatably coupled to a remainder of the rotor at a hinged joint and thereby extending along a length of the body in a storage configuration and extending radially outward from the body in a flight configuration. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/941133 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/50 (20130101) Original (OR) Class B64C 39/024 (20130101) B64C 2201/08 (20130101) B64C 2201/18 (20130101) B64C 2201/024 (20130101) B64C 2201/042 (20130101) B64C 2201/108 (20130101) B64C 2201/126 (20130101) B64C 2201/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793327 | Weimer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| ASSIGNEE(S) | Terumo BCT Biotechnologies, LLC (Lakewood, Colorado) |
| INVENTOR(S) | Kirk L. Weimer (Green Valley, Arizona); Nate T. Johnson (Highlands Ranch, Colorado); Dennis J. Hlavinka (Arvada, Colorado); Kestas P. Parakininkas (Englewood, Colorado) |
| ABSTRACT | Provided is a multi-part lyophilization container for lyophilizing a fluid, storing the lyophilizate, reconstituting the lyophilizate, and infusing the reconstituted lyophilizate into a patient, including a method of using same. The container includes a front surface, a back surface, a non-breathable section including a port region, a breathable section including a breathable membrane, and an occlusion zone encompassing a boundary between the non-breathable section and the breathable section. The non-breathable section is configured to accommodate any of a liquid, a solid, a gas or combination thereof. The breathable section is configured to accommodate only a gas. The method includes creating a temporary seal between the non-breathable section of the container and the breathable section, inputting a liquid into the non-breathable section, freezing the liquid, removing the temporary seal to allow vapor transport between the non-breathable section and the breathable section, and adding heat energy the frozen liquid under vacuum. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/154976 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0263 (20130101) A01N 1/0284 (20130101) A01N 1/0289 (20130101) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) A61J 1/1468 (20150501) A61J 1/2093 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 51/241 (20130101) Original (OR) Class Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/06 (20130101) F26B 25/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793454 | Russell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Morgan Russell (Dayton, Ohio); John Stubbs (Xenia, Ohio); David Kempisty (Beavercreek, Ohio) |
| ABSTRACT | A reactor system for treating contaminated water is disclosed. The reactor system includes a reactor vessel having first and second end portions and an internal reactor volume defined by interior surfaces of the reactor vessel. A fluoropolymer coating is applied over at least a portion of the interior surfaces of the reactor vessel. The reactor system also includes a water inlet disposed in the first end portion and a water outlet disposed in the second end portion. At least one ultraviolet light-emitting diode (LED) is included and disposed so as to project ultraviolet light into the reactor vessel. A plurality of photo-catalyst substrates are also disposed within the internal reactor volume of the reactor vessel. Each of these substrates includes a coating of titanium dioxide applied to an outer surface of a substrate. A method for remediating contaminated water is also disclosed. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902003 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 35/02 (20130101) B01J 35/004 (20130101) B01J 37/0217 (20130101) B01J 37/0225 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/725 (20130101) Original (OR) Class C02F 2201/3222 (20130101) C02F 2201/3227 (20130101) C02F 2201/3228 (20130101) C02F 2303/04 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793478 | Garnier |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Ceramic Fibers, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | ADVANCED CERAMIC FIBERS, LLC. (Idaho Falls, Idaho) |
| INVENTOR(S) | John E. Garnier (Idaho Falls, Idaho) |
| ABSTRACT | Ceramic composite materials that are reinforced with carbide fibers can exhibit ultra-high temperature resistance. For example, such materials may exhibit very low creep at temperatures of up to 2700° F. (1480° C.). The present composites are specifically engineered to exhibit matched thermodynamically stable crystalline phases between the materials included within the composite. In other words, the reinforcing fibers, a debonding interface layer disposed over the reinforcing fibers, and the matrix material of the composite may all be of the same crystalline structural phase (all hexagonal), for increased compatibility and improved properties. Such composite materials may be used in numerous applications. |
| FILED | Monday, July 09, 2018 |
| APPL NO | 16/030145 |
| ART UNIT | 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/571 (20130101) C04B 35/573 (20130101) C04B 35/573 (20130101) C04B 35/589 (20130101) C04B 35/591 (20130101) C04B 35/806 (20130101) Original (OR) Class C04B 35/62863 (20130101) C04B 35/62865 (20130101) C04B 35/62868 (20130101) C04B 35/62897 (20130101) C04B 37/005 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/0061 (20130101) C04B 38/0074 (20130101) C04B 2111/0081 (20130101) C04B 2111/00362 (20130101) C04B 2111/00431 (20130101) C04B 2111/00793 (20130101) C04B 2111/00801 (20130101) C04B 2111/00862 (20130101) C04B 2235/80 (20130101) C04B 2235/383 (20130101) C04B 2235/386 (20130101) C04B 2235/524 (20130101) C04B 2235/526 (20130101) C04B 2235/767 (20130101) C04B 2235/3865 (20130101) C04B 2235/3882 (20130101) C04B 2235/5244 (20130101) C04B 2235/5248 (20130101) C04B 2235/5264 (20130101) C04B 2235/5292 (20130101) C04B 2235/5296 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793609 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Kuan-Ta Lu (Cambridge, Massachusetts); Sara da Luz Areosa Cleto (Quincy, Massachusetts) |
| ABSTRACT | Provided herein are synthetic pathways from Escherichia coli and Vibrio cholerae genes for the production of new, synthetic nonribosomal peptides, and methods and compositions comprising the same. Some aspects of the present disclosure are directed to modified bacterial cells comprising a compressed biosynthetic pathway that comprises (a) biosynthetic genes obtained from one species encoding enzymes active in the bioassembly of a nonribosomal molecule, (b) biosynthetic genes obtained from another species encoding enzymes active in the bioassembly of a nonribosomal molecule that is different from the nonribosomal molecule of (a). In some embodiments, the biosynthetic genes of (a) are Escherichia coli biosynthetic genes and may include entD gene, an entC gene, an entE gene, an entB gene and an entA gene. In some embodiments, the biosynthetic genes of (b) are Vibrio cholera biosynthetic genes and may include a vibH gene and a vibF gene. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/579631 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793649 | Russell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts); The Research Foundation For The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Amherst, New York) |
| INVENTOR(S) | Thomas P. Russell (Amherst, Massachusetts); Duk Man Yu (Amherst, Massachusetts); Javid Rzayev (Williamsville, New York); Jose Kenneth D. Mapas (Amherst, New York) |
| ABSTRACT | A method of forming a microphase separated block copolymer includes exposing a block copolymer to acid vapor under conditions effective to provide the microphase separated block copolymer. The block copolymer includes a first hydrophobic block and a second hydrophobic block that is acid-sensitive. The microphase separated block copolymer includes the first hydrophobic block and a hydrophilic block derived from the second hydrophobic block. Exposing the block copolymer to the acid vapor is conducted in the solid state. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179078 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 6/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793840 | Tabor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jeffrey J. Tabor (Houston, Texas); Sebastian Schmidl (Houston, Texas); Ravi Sheth (Houston, Texas); Felix Ekness (Houston, Texas); Brian Landry (Houston, Texas); Nikola Dyuglyarov (Houston, Texas) |
| ABSTRACT | Methods to create two component signal transduction systems by replace the DNA binding domains and output promoters in bacteria are described. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/571744 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Original (OR) Class C12N 9/1229 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/13003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793853 | Medina-Kauwe |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lali K. Medina-Kauwe (Porter Ranch, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Lali K. Medina-Kauwe (Porter Ranch, California) |
| ABSTRACT | The present invention relates a targeted delivery system for siRNA or antisense technology. In one embodiment, the invention provides for a method of treating cancer by administering a therapeutically effective dosage of HerPBK10 combined with siRNA, resulting in the inhibition of Her2 expression and cell death. In another embodiment, a plurality of HerPBK10 combined with siRNA form a nanoparticle. |
| FILED | Friday, July 22, 2011 |
| APPL NO | 13/189265 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/32 (20130101) C12N 2710/10322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793865 | Phillips et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Phillips (Washington, District of Columbia); Sarah M. Glaven (Washington, District of Columbia) |
| ABSTRACT | A prokaryotic protein appearing to have a Bin/Amphiphysin/Rvs (BAR) domain, previously known in eukaryotes, has been identified. Expression of this protein causes formation of outer membrane extensions. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/421839 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794207 | Hough |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RATHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Matthew Andrew Hough (West Hartford, Connecticut) |
| ABSTRACT | A gas turbine engine component array includes first and second components each having a platform. The platforms are arranged adjacent to one another and provide a gap. A seal is arranged circumferentially between the first and second components and in engagement with the platforms to obstruct the gap. A cooling hole is provided in the seal and is in fluid communication with the gap. The cooling hole has an increasing taper toward the gap. |
| FILED | Thursday, September 11, 2014 |
| APPL NO | 15/022025 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) F01D 5/187 (20130101) F01D 5/225 (20130101) F01D 5/3007 (20130101) F01D 9/041 (20130101) F01D 11/006 (20130101) Original (OR) Class F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/55 (20130101) F05D 2240/57 (20130101) F05D 2240/81 (20130101) F05D 2250/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794272 | Higgins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Timothy Joseph Higgins (Newburyport, Massachusetts) |
| ABSTRACT | A turbine engine includes a compressor section including a compressor, the compressor including an axial compressor stage, a variable outlet guide vane, and a centrifugal compressor stage, the variable outlet guide vane positioned between the axial compressor stage and the centrifugal compressor stage; a bleed assembly including a bleed airflow duct in airflow communication with the compressor and a bleed valve operable with the bleed airflow duct, the bleed valve including a bleed valve actuator; and a linkage assembly coupling the bleed valve actuator with the variable outlet guide vane such that that variable outlet guide vane is moveable with the bleed valve. |
| FILED | Monday, February 19, 2018 |
| APPL NO | 15/898786 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) Original (OR) Class F02C 9/18 (20130101) F02C 9/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/56 (20130101) F05D 2260/57 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794273 | Perlak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jeffery F. Perlak (South Windsor, Connecticut); Joseph B. Staubach (Colchester, Connecticut); Gabriel L. Suciu (Glastonbury, Connecticut); James D. Hill (Tolland, Connecticut); Frederick M. Schwarz (Glastonbury, Connecticut) |
| ABSTRACT | A gas turbine engine according to the present disclosure includes a first compressor and a first turbine for driving the first compressor. A core section includes a second compressor and a second turbine for driving the second compressor. A third turbine is arranged fluidly downstream of the first turbine and the second turbine and configured to drive a power take-off. A first duct system is arranged fluidly between the low-pressure compressor and the core section. The first duct system is arranged to reverse fluid flow before entry into the core section. |
| FILED | Wednesday, July 01, 2015 |
| APPL NO | 14/789036 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) F02C 3/107 (20130101) Original (OR) Class F02C 3/145 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2210/44 (20130101) F05D 2260/4031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794332 | Gagne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Kevin R. Gagne (Manchester, New Hampshire); Darren L. Hitt (Burlington, Vermont); Michael Ryan McDevitt (Burlington, Vermont) |
| ABSTRACT | Systems, apparatuses, and methods for generating hot gases based on catalyzation involving flowing catalyst. Catalysis occurs in a flow-type mixing catalyzation channel in which a liquid catalyst mixes with a liquid reactant flowing in a desired flow regime, such as a striated (laminar) flow regime or a slug flow regime. Devices such as micro-thrusters for satellite and other applications and hot gas generators for powering another device, such as an electrical generator, can be made using one or more flow-type mixing catalyzation channels. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354508 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/26 (20130101) B64G 1/401 (20130101) B64G 1/402 (20130101) Jet-propulsion Plants F02K 9/56 (20130101) Original (OR) Class F02K 9/88 (20130101) F02K 9/94 (20130101) F02K 9/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794340 | Kokjohn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Sage Kokjohn (Oregon, Wisconsin); David Wickman (Madison, Wisconsin); Flavio Dal Forno Chuahy (Madison, Wisconsin) |
| ABSTRACT | A first engine fuel, for example diesel fuel, is reformed (preferably via steam reforming) to produce syngas for use as a second engine fuel, with the fuels then both being used in an internal combustion engine to perform Reactivity Controlled Compression Ignition (RCCI). The syngas is produced and supplied to the engine as a supercritical fluid, thereby avoiding the pumping losses that would occur if syngas was pressurized for supply/injection. The reforming is done by a reformer which is provided as a unit with the engine (e.g., both the engine and reformer are onboard a vehicle), thereby effectively allowing use of a single fuel for RCCI engine operation. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/960735 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 17/005 (20130101) F02B 45/00 (20130101) F02B 51/00 (20130101) F02B 2201/06 (20130101) F02B 2275/14 (20130101) Controlling Combustion Engines F02D 19/0649 (20130101) F02D 41/0025 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 31/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794673 | Rastegar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jahangir S Rastegar (Stony Brook, New York); Jacques Fischer (Sound Beach, New York) |
| ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York); Jacques Fischer (Sound Beach, New York) |
| ABSTRACT | A munition including: a control surface actuation device including: an actuator comprising two or more pistons, each of the pistons being movable between an extended and retracted position, the retracted position resulting from an activation of each of the two or more pistons; and a rotatable plate having a pocket corresponding to each of the two or more pistons, each pocket being engageable with a corresponding portion of each of the two or more pistons, a distance between the pockets being different than a distance between the portions of the two or more pistons, such that activation of the portion into the corresponding pocket sequentially rotates the plate; and a control surface operatively connected to the plate such that rotation of the plate rotates the control surface. |
| FILED | Saturday, April 08, 2017 |
| APPL NO | 15/482737 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/18 (20130101) F42B 10/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794819 | Ashcom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan Ashcom (Cambridge, Massachusetts); Sumanth Kaushik (Belmont, Massachusetts) |
| ABSTRACT | A method and apparatus used for detecting gaseous chemicals. The method and apparatus use an interferometer to filter received light by wavelength, creating an image only using light with wavelengths that are affected by the presence of a gaseous chemical. A reference image composed of light with wavelengths unaffected by the presence of a gaseous chemical is also created and used as a reference. A gaseous chemical is detected where the ratio of the intensity of the two images changes. Despite the high spectral resolution of the filter, the system can operate with a very wide field of view. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/152809 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/255 (20130101) Original (OR) Class G01N 21/3504 (20130101) Optical Elements, Systems, or Apparatus G02B 27/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794828 | Zhuang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Lexington, Massachusetts); Wilfred M. Bates (Gottingen, Germany); Michael J. Rust (Somerville, Massachusetts) |
| ABSTRACT | The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The entities may be immobilized relative to each other and/or to a common entity. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction limit resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA, a protein, a cell, a tissue, etc. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction limit image resolution, computer programs and techniques for sub-diffraction limit image resolution, methods for promoting sub-diffraction limit image resolution, methods for producing photoswitchable entities, and the like. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058525 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) C09K 2211/1044 (20130101) C09K 2211/1475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1475 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/582 (20130101) G01N 2015/0065 (20130101) G01N 2021/6421 (20130101) G01N 2021/6439 (20130101) G01N 2021/6441 (20130101) G01N 2201/12 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794871 | Blackshire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | James L. Blackshire (Bellbrook, Ohio); Jeong K. Na (Centerville, Ohio) |
| ABSTRACT | An apparatus for non-destructive ultrasonic testing is disclosed that permits focused immersion measurements to be accomplished in a non-immersion, contact mode. The apparatus includes an adaptor for acoustically coupling an elastomeric body to a focused ultrasonic transducer via an acoustic couplant. The adaptor includes a housing for receiving the elastomeric body on one end, and the ultrasonic transducer on another end. A cavity is defined within the housing for receiving a liquid medium that acoustically couples the ultrasonic transducer to the elastomeric body. The elastomeric body has a frontal surface disposed at a face slant angle relative to a longitudinal axis, where the face slant angle can be optimized for the test material. The volume of the housing cavity may be adjusted so as to vary the focal length of the ultrasonic transducer. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 15/987168 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/11 (20130101) G01N 29/24 (20130101) G01N 29/28 (20130101) G01N 29/262 (20130101) G01N 29/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794914 | Clinton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles M. Clinton (Clarksburg, Maryland); Eli N. Glezer (Chevy Chase, Maryland); Bandele Jeffrey-Coker (Darnestown, Maryland); Sandor L. Kovacs (Middletown, Delaware); Sudeep M. Kumar (Gaithersburg, Maryland); George Sigal (Rockville, Maryland); Carl Stevens (Silver Spring, Maryland); Michael Vock (Loveland, Ohio) |
| ASSIGNEE(S) | MESO SCALE TECHNOLOGIES, LLC (Rockville, Maryland) |
| INVENTOR(S) | Charles M. Clinton (Clarksburg, Maryland); Eli N. Glezer (Chevy Chase, Maryland); Bandele Jeffrey-Coker (Darnestown, Maryland); Sandor L. Kovacs (Middletown, Delaware); Sudeep M. Kumar (Gaithersburg, Maryland); George Sigal (Rockville, Maryland); Carl Stevens (Silver Spring, Maryland); Michael Vock (Loveland, Ohio) |
| ABSTRACT | We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring. |
| FILED | Saturday, November 05, 2011 |
| APPL NO | 13/290059 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Applying Closure Members to Bottles Jars, or Similar Containers; Opening Closed Containers B67B 7/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/66 (20130101) G01N 21/6452 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/5302 (20130101) G01N 35/028 (20130101) G01N 35/109 (20130101) G01N 35/1002 (20130101) G01N 35/1011 (20130101) G01N 35/1079 (20130101) G01N 35/1081 (20130101) G01N 2035/0405 (20130101) G01N 2035/0425 (20130101) G01N 2035/1025 (20130101) Technical Subjects Covered by Former US Classification Y10T 83/9314 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794921 | Ratner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Puget Sound Blood Center (Seattle, Washington) |
| INVENTOR(S) | Daniel M. Ratner (Seattle, Washington); Jill M. Johnsen (Seattle, Washington); James T. Kirk (Seattle, Washington); José A. López (Seattle, Washington); Norman D. Brault (Seattle, Washington); Shaoyi Jiang (Redmond, Washington) |
| ABSTRACT | Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047911 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/75 (20130101) G01N 21/7703 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795029 | Stastny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Stastny (San Diego, California); Bryan D. Bagnall (San Francisco, California); Sparta Cheung (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John Stastny (San Diego, California); Bryan D. Bagnall (San Francisco, California); Sparta Cheung (San Diego, California) |
| ABSTRACT | An Automatic Identification System (AIS) transponder and method for transmitting vessel AIS data can include an onboard processor and database, a VHF AIS transceiver and cellular modem connected to the processor, and a navigation sub-system for providing position inputs to the processor. The processor can include written instructions for transmitting only single sentence AIS messages when the transponder is within RsAIS of a satellite but outside range RtAIS of a terrestrial AIS base station, and switching to the base station when the vessel is within RtAIS but outside of cellular modem range, Rcell. While transmitting to the AIS satellite or AIS base station, portions of the vessel AIS are recorded to the database as historical data. Once within Rcell, the transponder can switch to transmission via cellular modem to an AIS architecture server. Historical data can also be downloaded to complete and update the vessel AIS data profile within AIS. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 15/895202 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 69/00 (20130101) B63B 2203/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) G01C 21/203 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795186 | Kotov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Nicholas A. Kotov (Ypsilanti, Michigan); Joong Hwan Bahng (Ann Arbor, Michigan) |
| ABSTRACT | Optical materials for optical devices are provided that comprise a plurality of hedgehog-shaped microparticles. Each hedgehog microparticle comprises a core region formed of a first material having a first refractive index and a plurality of needles connected to and substantially orthogonal to a surface of the core region. The needles comprise a second material having a second refractive index. The optical material enhances forward scattering of a predetermined wavelength of light, while suppressing backscattering of the predetermined wavelength of light. Methods of controlling transparency in an optical material comprising a plurality of hedgehog microparticles, while suppressing backscattering are also provided. Spectral tuning with use of such optical materials is also provided. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826081 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 9/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/20 (20130101) C08J 5/12 (20130101) C08J 5/18 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) Optical Elements, Systems, or Apparatus G02B 1/10 (20130101) G02B 5/0242 (20130101) G02B 5/0294 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795234 | Brongersma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Mark L. Brongersma (Menlo Park, California); Aaron L. Holsteen (Stanford, California) |
| ABSTRACT | A monolithic optical device for light manipulation and control at visible wavelengths includes a device layer deposited on an sacrificial layer deposited on a reflective substrate. The device layer comprises an elastic support structure and nanoscale optical antenna elements, arranged such that the nanoscale optical antenna elements are capable of moving vertically in response to application of an electrostatic potential between the device layer and the reflective substrate. The sacrificial layer joins the elastic support structure to the reflective substrate. The reflective substrate is reflective at optical wavelengths. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956695 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/08 (20130101) G02B 5/1809 (20130101) G02B 7/1822 (20130101) G02B 26/0808 (20130101) G02B 26/0841 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/29 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795323 | Skertic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Richard Joseph Skertic (Carmel, Indiana) |
| ABSTRACT | In some examples, a method includes determining, by a controller in a system, a result of a first control loop based on a first sensed signal in a first instance and determining, by the controller, a result of a second control loop based on a second sensed signal in a second instance. The method also includes clamping, by the controller, the result of the second control loop to be equal to the result of the first control loop in the first instance and clamping, by the controller, the result of the first control loop to be equal to the result of the second control loop in the second instance. The method further includes outputting, by the controller and to a component of the system, a control signal based on the result of the first control loop. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123526 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10795819 — Multi-processor system with configurable cache sub-domains and cross-die memory coherency
| US 10795819 | Pawlowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Robert Pawlowski (Beaverton, Oregon); Bharadwaj Krishnamurthy (Hillsboro, Oregon); Vincent Cave (Hillsboro, Oregon); Jason M. Howard (Portland, Oregon); Ankit More (San Mateo, California); Joshua B. Fryman (Corvallis, Oregon) |
| ABSTRACT | Disclosed embodiments relate to a system with configurable cache sub-domains and cross-die memory coherency. In one example, a system includes R racks, each rack housing N nodes, each node incorporating D dies, each die containing C cores and a die shadow tag, each core including P pipelines and a core shadow tag, each pipelines associated with a data cache and data cache tags and being either non-coherent or coherent and one of X coherency domains, wherein each pipeline, when needing to read a cache line, issues a read request to its associated data cache, then, if need be, issues a read request to its associated core-level cache, then, if need be, issues a read request to its associated die-level cache, then, if need be, issues a no-cache remote read request to a target die being mapped to hold the cache line. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/453670 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3816 (20130101) G06F 9/30116 (20130101) G06F 9/30138 (20130101) G06F 12/0811 (20130101) G06F 12/0828 (20130101) Original (OR) Class G06F 12/0891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795896 | Contractor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Noshir S. Contractor (Evanston, Illinois); Harshad E. Gado (Evanston, Illinois); Anup S. Sawant (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure include a system that automatically defines and assembles a group of users capable of solving a particular problem, such as problems associated with network platforms and infrastructures. The group of users are identified from user data captured while users interact within and throughout a network, such as a social network. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927721 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/248 (20190101) G06F 16/951 (20190101) G06F 16/24575 (20190101) G06F 16/24578 (20190101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 10/063112 (20130101) G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796252 | Werho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trevor N. Werho (Mesa, Arizona); Junshan Zhang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Trevor N. Werho (Mesa, Arizona); Junshan Zhang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
| ABSTRACT | Systems and methods for forecasting power generation in a wind farm are disclosed. The systems and methods utilize an induced Markov chain model to generate a forecast of power generation of the wind farm. The forecast is at least one of a point forecast or a distributional forecast. Additionally, the systems and methods modify at least one of: (i) a generation of electricity at a power plant coupled to a common power grid as the wind farm; or (ii) a distribution of electricity in the common power grid based on the forecast of power generation of the wind farm. In an exemplary approach, utilizing the induced Markov chain model to generate the forecast may include determining a series of time adjacent power output measurements based on historical wind power measurements and calculating a time series of difference values based on the series of time adjacent power output measurements. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/555490 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) Original (OR) Class G06Q 30/0283 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/386 (20130101) H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796596 | Skorheim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Steven W. Skorheim (Canoga Park, California); Michael D. Howard (Westlake Village, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | Described is a closed-loop intervention control system for memory consolidation in a subject. During operation, the system simulates memory changes of a first memory in a subject during waking encoding of the memory, and then while the subject is sleeping and coupled to an intervention system. Based on the simulated memory changes, the system predicts behavioral performance for the first memory, the behavioral performance being a probability that the first memory can be recalled on cue. The system can be used to control operation (e.g., turn on or off) of the intervention system with respect to the first memory based on the behavioral performance of the first memory determined by the simulation. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/798325 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/0402 (20130101) A61B 5/0476 (20130101) A61B 5/486 (20130101) A61B 5/0488 (20130101) A61B 5/4812 (20130101) A61B 5/4836 (20130101) A61B 5/7275 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) A61M 21/02 (20130101) A61M 2021/0016 (20130101) A61M 2021/0027 (20130101) A61M 2021/0072 (20130101) A61M 2205/502 (20130101) A61M 2230/04 (20130101) A61M 2230/10 (20130101) A61M 2230/18 (20130101) A61M 2230/60 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36025 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/0265 (20130101) G05B 17/02 (20130101) G05B 19/048 (20130101) G05B 2219/23026 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796599 | Hargrove et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Levi J. Hargrove (Chicago, Illinois); Richard B. Woodward (Chicago, Illinois) |
| ABSTRACT | An apparatus comprising an electromyographic (EMG) control module is disclosed. The apparatus includes an electromyographic (EMG) control module configured to receive EMG information generated by an individual; identify a gesture class based on the EMG information, and train using the received EMG information and the gesture class. The gesture class corresponds to an intended gesture made by the individual. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954417 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0488 (20130101) A61B 5/0492 (20130101) A61B 5/681 (20130101) A61B 5/6811 (20130101) A61B 5/6824 (20130101) A61B 5/7405 (20130101) Electric Digital Data Processing G06F 3/017 (20130101) Image Data Processing or Generation, in General G06T 19/003 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/003 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797215 | Russ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boris Russ (Berkeley, California); David Brown (Washington, District of Columbia); Jared Lynch (Fremont, California); Tristan Day (Whittier, California); Nelson E. Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jason D. Forster (Berkeley, California); Jeffrey Snyder (Pasadena, California); Jeffrey J. Urban (Emeryville, California); Rachel A. Segalman (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Boris Russ (Berkeley, California); David Brown (Washington, District of Columbia); Jared Lynch (Fremont, California); Tristan Day (Whittier, California); Nelson E. Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jason D. Forster (Berkeley, California); Jeffrey Snyder (Pasadena, California); Jeffrey J. Urban (Emeryville, California); Rachel A. Segalman (Santa Barbara, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to graded thermoelectric materials. In one aspect, a method includes providing a plurality of nanostructures. The plurality of nanostructures comprise a thermoelectric material, with nanostructures of the plurality of nanostructures having first ligands disposed on surfaces of the nanostructures. The plurality of nanostructures is deposited on a substrate to form a layer. The layer is contacted with a solution containing second ligands. A ligand exchange process occurs where some of the first ligands disposed on the plurality of nanostructures are replaced with the second ligands. A first region of the layer is removed from contact with the solution so that the ligand exchange process does not occur in the first region of the layer, with the ligand exchange process occurring in the layer in contact with the solution. The layer is then removed from contact with the solution. |
| FILED | Thursday, September 01, 2016 |
| APPL NO | 15/254918 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) H01L 35/26 (20130101) Original (OR) Class H01L 35/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797522 | Chappell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | William J. Chappell (Lafayette, Indiana); Dohyuk Ha (Lafayette, Indiana); Henry Mei (West Lafayette, Indiana); Pedro P. Irazoqui (West Lafayette, Indiana) |
| ABSTRACT | A wireless power transfer system is disclosed. The system includes a first resonator having a first resonant frequency ωo1, a half power bandwidth Δω1, and an unloaded quality factor Qo1=ωo1/Δω1 coupled through a first coupling circuit to a power source, a second resonator having a second resonant frequency ωo2, a half power bandwidth Δω2, and an unloaded quality factor Qo2=ωo2/Δω2 coupled through a second coupling circuit to a load, the first resonator disposed a distance away from the second resonator, wherein the distance is smaller than the first and second resonant wavelengths, the first and second coupling circuits are configured so that up to a maximum achievable power transfer efficiency between the first and second resonators can be achieved, wherein Qo1 and Qo2 can be less than 100. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/056543 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class H02J 50/50 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797628 | French et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Mat French (Avon, Indiana); John T. Alt (Zionsville, Indiana); Mark J. Blackwelder (Plainfield, Indiana) |
| ABSTRACT | A gas turbine engine includes first and second electrical machines coupled to the gas turbine engine, each of the first and second electrical machines electrically coupled to both a primary electrical bus and a secondary electrical bus. The gas turbine includes a first controller configured to control operation of the gas turbine engine, and a second controller coupled to the first controller, the second controller configured to respond to control inputs from the first controller and control an electrical output of the first and second electrical machines to the primary and secondary electrical busses. A converter controller is coupled to an energy storage system, the second controller, the primary electrical bus, and the secondary electrical bus. |
| FILED | Wednesday, March 15, 2017 |
| APPL NO | 15/459577 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) B81B 2201/0257 (20130101) B81B 2201/0264 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00158 (20130101) B81C 1/00301 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/32 (20130101) F02C 7/36 (20130101) F02C 7/268 (20130101) F02C 9/00 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Starting of Combustion Engines; Starting Aids for Such Engines, Not Otherwise Provided for F02N 11/0862 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/706 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/76 (20130101) F05D 2270/62 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/16 (20130101) H02J 1/102 (20130101) H02J 3/30 (20130101) H02J 3/32 (20130101) H02J 3/38 (20130101) H02J 9/061 (20130101) Dynamo-electric Machines H02K 7/1823 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/48 (20130101) Original (OR) Class H02P 2101/25 (20150115) H02P 2101/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10798651 | Xiong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fusion Technology, Inc (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Wenhao Xiong (Germantown, Maryland); Yi Li (Germantown, Maryland); Xin Tian (Germantown, Maryland); Dan Shen (Germantown, Maryland); Nichole Sullivan (Germantown, Maryland); Biao Chen (Jamesville, New York); Genshe Chen (Germantown, Maryland) |
| ABSTRACT | A three-layer protocol stack in a wireless communication device and a wireless communication network are provided. The three-layer protocol stack includes a physical layer; a medium access control (MAC) layer; and a network layer. The physical layer includes one or more circuits to conduct a power consumption minimization and a waveform selection. The MAC layer is configured to perform a medium access control and a resource block reconfiguration. The network layer is configured to perform an energy efficient routing and connection maintenance. The physical layer, the MAC layer and the network layer cooperate with each other to at least reduce an energy consumption of the wireless communication device. |
| FILED | Friday, August 17, 2018 |
| APPL NO | 16/104760 |
| ART UNIT | 2477 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 28/18 (20130101) H04W 52/0203 (20130101) Original (OR) Class H04W 80/02 (20130101) H04W 80/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10793442 | Winter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Horst H. Winter (Amherst, Massachusetts); Wei Fan (Amherst, Massachusetts); Vijesh Tanna (Amherst, Massachusetts); Sanket Sabnis (Amherst, Massachusetts) |
| ABSTRACT | A method for forming zeolite nanosheets includes forming a mixture including a layered zeolite precursor and a functionalized polymer and exfoliating the layered zeolite precursor to provide the zeolite nanosheets. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/440704 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 37/0215 (20130101) B01J 2231/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/026 (20130101) Original (OR) Class C01B 39/48 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/24 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 9/04 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 9/00 (20130101) C08L 2666/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793450 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
| INVENTOR(S) | Xin Gao (Lexington, Kentucky); Ayokunle Omosebi (Lexington, Kentucky); James Richardson Landon (Lexington, Kentucky); Kunlei Liu (Lexington, Kentucky) |
| ABSTRACT | The invention is a capacitive, aka electrostatic, deionization apparatus and method that solves the problem of short lifetime of conventional capacitive deionization (CDI) and of membrane capacitive deionization (MCDI) devices and methods by shifting the Potential of Zero Charge of electrode surfaces through surface modifications. Such electrode surface modifications provide very long lifetime capacitive deionization devices and methods. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 14/757209 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) Original (OR) Class C02F 2001/46138 (20130101) C02F 2209/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793506 | Rorrer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Nicholas Rorrer (Golden, Colorado); Gregg Tyler Beckham (Golden, Colorado); Caroline Bradshaw Hoyt (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a first repeat unit defined by where R includes a first hydrocarbon chain that includes at least one olefinic bond, R5 includes a second hydrocarbon chain, the second hydrocarbon chain may be saturated, and n may be between 2 and 1,000. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/789794 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/44 (20130101) Original (OR) Class C07C 69/602 (20130101) Compositions of Macromolecular Compounds C08L 77/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793546 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (, None) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Liang Huang (Mesa, Arizona); Tyler Fleetham (Gilbert, Arizona) |
| ABSTRACT | Complexes and devices, such as organic light emitting devices and full color displays, including a compound of the formula wherein: M is Pd2+, Ir+, Rh+, or Au3+; each of V1, V2, V3, and V4 is coordinated to M and is independently N, C, P, B, or Si; each of L1, L2, L3, and L4 is independently a substituted or unsubstituted aryl, cycloalkyl, cycloalkenyl, heterocyclyl, heteroaryl, carbene, or N-heterocyclic carbene; and Z is O, S, NR, CR2, SiR2, BR, PR, where each R is independently substituted or unsubstituted C1-C4 alkyl or substituted or unsubstituted aryl. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 15/503690 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/12 (20130101) C07F 7/0803 (20130101) C07F 9/5045 (20130101) C07F 15/006 (20130101) C07F 15/0033 (20130101) C07F 15/0073 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/18 (20130101) C09K 2211/185 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1029 (20130101) C09K 2211/1044 (20130101) C09K 2211/1074 (20130101) C09K 2211/1096 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/50 (20130101) H01L 51/0067 (20130101) H01L 51/0081 (20130101) H01L 51/0084 (20130101) H01L 51/5016 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793673 | Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Nacu Hernandez (Ames, Iowa); Mengguo Yan (Ames, Iowa); Eric W. Cochran (Ames, Iowa); John Edward Matthiesen (Ames, Iowa); Jean-Philippe Tessonnier (Ames, Iowa) |
| ABSTRACT | The present invention relates to a polymer comprising a repeating group having the structure of formula (I) wherein R, R1, R2, R3, R4, X, and s are as described herein and salt thereof. Also disclosed is a process of synthesizing such polymers. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348561 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/26 (20130101) C08G 69/28 (20130101) C08G 69/48 (20130101) C08G 69/265 (20130101) Original (OR) Class C08G 77/455 (20130101) C08G 81/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793699 | Ciesielski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Peter N. Ciesielski (Arvada, Colorado); Ruoran Zhang (Lakewood, Colorado); Michael E. Himmel (Littleton, Colorado); Andrew Nolan Wilson (Denver, Colorado); Mark R. Nimlos (Golden, Colorado) |
| ABSTRACT | Disclosed herein are a cellulose particle and a binder, where the cellulose particle has a cellulose core and a surface group, and the binder interacts with the surface group to form a composite. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902429 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/19 (20130101) C08K 5/098 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class C08L 2203/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793728 | Bohnert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | George Bohnert (Harrisonville, Missouri); Jamie Messman (Kansas City, Missouri) |
| ABSTRACT | An improved superhydrophobic coating and a process of making it is provided herein. More particularly, a robust superhydrophobic coating is produced by using carbon dioxide to enhance the integration of a binder material into the superhydrophobic coating. The carbon dioxide may be used to infiltrate and fill the interstitial voids of a superhydrophobic material, such as diatomaceous earth. Consequently, occupying these voids in the superhydrophobic material effectively blocks other components (e.g., binders) from entering the voids. As a result, the coating formulations of the present invention are more robust and may strongly adhere to the substrates to which they are applied. |
| FILED | Wednesday, June 06, 2018 |
| APPL NO | 16/001479 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/025 (20130101) B05D 5/08 (20130101) B05D 2401/00 (20130101) B05D 2401/00 (20130101) B05D 2401/90 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/20 (20130101) C08K 3/36 (20130101) C08K 7/26 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/28 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/61 (20180101) C09D 7/62 (20180101) Original (OR) Class C09D 7/80 (20180101) C09D 133/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793820 | Sheth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Heeral Sheth (San Francisco, California); Haiyin Chen (San Ramon, California); Bryan D. Hudson (Livermore, California); Kris Kulp (Livermore, California); Margaret W. Mcnerney (Pleasanton, California); Satinderpall S. Pannu (Pleasanton, California); Fang Qian (Santa Cruz, California); Angela C. Tooker (Dublin, California); Elizabeth K. Wheeler (Livermore, California); Vanessa Tolosa (Emeryville, California) |
| ABSTRACT | In one embodiment, a system includes a bioreactor coupled to a substrate. The bioreactor includes: a plurality of walls defining a reservoir; a plurality of fluidic channels in at least some of the walls; a fluidic inlet in fluidic communication with the reservoir via, the fluidic channels; a fluidic outlet in fluidic communication with the reservoir via the fluidic channels; and one or more sensors coupled to the reservoir, each sensor being configured to detect one or more of: environmental conditions in the reservoir; and physiological conditions of one or more cells optionally present in the reservoir. In another embodiment, a method includes delivering media to a reservoir of a bioreactor; delivering a plurality of cells to the reservoir, controlling a reservoir temperature and a reservoir gas composition; using one or more of the sensors to monitor environmental and physiological conditions; and reporting the environmental and/or physiological conditions. |
| FILED | Tuesday, April 29, 2014 |
| APPL NO | 14/265019 |
| ART UNIT | 1799 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Original (OR) Class C12M 41/26 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793851 | Gill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Ryan T. Gill (Denver, Colorado); Ramsey Zeitoun (Gaithersburg, Maryland) |
| ABSTRACT | Compositions and methods for tracking combinations of mutations in populations by coupling DNA assembly and paired-end sequencing technology with high-throughput sequencing. This allows for an unlimited number of mutation sites in a population of microorganisms to be identified, and allows sites to be sequenced across several replicates. Unique identifiers (DNA barcodes) can be used to measure fitness data by sequencing of the barcodes multiplexed with the mutation sites with high-throughput short sequencing read technology, allowing selections to be rapidly performed on populations of known combinatorial genotypes. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/749540 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793863 | Mansoorabadi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AUBURN UNIVERSITY (Auburn, Alabama) |
| ASSIGNEE(S) | AUBURN UNIVERSITY (Auburn, Alabama) |
| INVENTOR(S) | Steven Mansoorabadi (Auburn, Alabama) |
| ABSTRACT | The present disclosure describes genes and proteins of the coenzyme F430 synthetic pathway. The genes and proteins in the pathway find uses as isolated nucleic acids, transformation vectors, a transformation media, genetically modified cells, methods of modulating methanogenesis, methods of modulating methane oxidation, methods of making a tetrapyrrole compound, methods of oxidizing methane, methods of biogenic methane synthesis is provided, methods of assaying an organism for potential methanogenic or methanotrophic activity, and isolated proteins. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 15/588396 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/93 (20130101) C12N 15/52 (20130101) Original (OR) Class C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/023 (20130101) Enzymes C12Y 499/01003 (20130101) C12Y 603/02013 (20130101) C12Y 603/05011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793964 | Divan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ralu Divan (Darien, Illinois); M. Tanim Humayun (Chicago, Illinois); Igor Paprotny (Chicago, Illinois); Lara A. Gundel (Berkeley, California) |
| ABSTRACT | A method of manufacturing a functionalized pre-treated carbon nanotube. Atomic Layer deposition is utilized to functionalize a pre-treated carbon nanotube. The functionalized pre-treated carbon nanotube may be used in a chemiresistor, including for methane detection. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/146718 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) C01B 2202/06 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 27/308 (20130101) G01N 33/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793979 | Ridley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Brent Ridley (Huntington Beach, California); Jean Chang (San Francisco, California); Shara Maikranz (Portland, Oregon) |
| ABSTRACT | A system and method of generating a coiled actuator fiber. The method includes twisting a fiber to generate a twisted fiber, wrapping the twisted fiber around a core to generate a coil in the twisted fiber; and removing at least a portion of the core to generate a coiled actuator fiber. In some aspects that fiber can be a yarn with one or more fibers or a fiber comprising a single elongated element. In some aspects, a portion of the core includes a removable sacrificial portion. The removable sacrificial portion can be dissolvable in a solvent or physically removable. In some aspects, the core further includes a non-dissolvable portion that is not dissolvable and generating a coiled actuator can include removing the sacrificial portion by treating a twisted fiber on the core to remove the sacrificial portion and leaving the non-dissolvable portion. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949881 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 1/205 (20130101) Original (OR) Class D02G 1/0286 (20130101) D02G 3/02 (20130101) D02G 3/36 (20130101) D02G 3/38 (20130101) D02G 3/326 (20130101) D02G 3/406 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/05 (20130101) D06M 11/84 (20130101) D06M 2101/20 (20130101) D06M 2101/32 (20130101) D06M 2101/34 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/06 (20130101) D10B 2331/02 (20130101) D10B 2401/04 (20130101) D10B 2401/024 (20130101) D10B 2501/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793981 | Ridley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Brent Ridley (Huntington Beach, California); Saul Griffith (San Francisco, California); Shara Maikranz (San Francisco, California); Jean Chang (San Francisco, California); Pete Lynn (Oakland, California) |
| ABSTRACT | An adaptive sheet that includes a first layer defining a first length, the first layer configured to assume a base configuration in response to a first environmental condition and assume a lofted configuration in response to a second environmental condition with the first layer being curled along the first length compared the base configuration. The first fabric layer includes a first material defining a second length and having a first expansion coefficient, and wherein the first material is configured to increasingly change length along the second length in response to the second environmental condition, and a second material defining a third length and having a second expansion coefficient that is different than the first expansion coefficient. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/160439 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 31/065 (20190201) A41D 2500/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/266 (20130101) B32B 5/04 (20130101) B32B 5/06 (20130101) B32B 5/12 (20130101) B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/026 (20130101) B32B 5/26 (20130101) B32B 7/05 (20190101) B32B 7/08 (20130101) B32B 7/12 (20130101) B32B 15/02 (20130101) B32B 15/04 (20130101) B32B 15/08 (20130101) B32B 15/14 (20130101) B32B 27/02 (20130101) B32B 27/08 (20130101) B32B 2250/02 (20130101) B32B 2250/20 (20130101) B32B 2250/24 (20130101) B32B 2262/02 (20130101) B32B 2307/30 (20130101) B32B 2307/51 (20130101) B32B 2307/54 (20130101) B32B 2307/56 (20130101) B32B 2307/58 (20130101) B32B 2307/304 (20130101) B32B 2307/416 (20130101) B32B 2307/516 (20130101) B32B 2307/518 (20130101) B32B 2307/546 (20130101) B32B 2307/554 (20130101) B32B 2307/706 (20130101) B32B 2307/724 (20130101) B32B 2307/732 (20130101) B32B 2307/7265 (20130101) B32B 2437/00 (20130101) B32B 2535/00 (20130101) B32B 2601/00 (20130101) Knitting D04B 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794771 | Congreve et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel N. Congreve (Cambridge, Massachusetts); Nicholas John Thompson (Hamilton, New Jersey); Mark W. B. Wilson (Somerville, Massachusetts); Mengfei Wu (Cambridge, Massachusetts); Marc A. Baldo (Lexington, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ABSTRACT | The present invention generally relates to composition and methods for downconverting light. In some embodiments, the composition and methods comprise an organic material, a nanocrystal, and a ligand capable of facilitating energy transfer between the organic material and the nanocrystal. In certain embodiments, the nanocrystal has a first excited energy state with an energy less than a triplet energy state of the organic material. The organic material, in some embodiments, may be aromatic and/or include one or more pi-conjugated carbon-carbon double bonds. In some cases, incident light may be absorbed by the organic material to produce two triplet excitons. The triplet excitons may then transfer to the nanocrystal via the ligand, where they can undergo recombination, resulting in the formation low energy photons. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/045011 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/661 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/00 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5012 (20130101) H01L 51/5016 (20130101) H01L 51/5028 (20130101) H01L 2251/5369 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794777 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | John E. Rogers (Owens Cross Roads, Alabama); Mark Sheplak (Gainesville, Florida); Yong Kyu Yoon (Gainesville, Florida); Jack Judy (Gainesville, Florida) |
| ABSTRACT | Methods and apparatuses for measuring static and dynamic pressures in harsh environments are disclosed. A pressure sensor according to one embodiment of the present invention may include a diaphragm constructed from materials designed to operate in harsh environments. A waveguide may be operably connected to the diaphragm, and an electromagnetic wave producing and receiving (e.g., sensing) device may be attached to the waveguide, opposite the diaphragm. A handle may be connected between the diaphragm and the waveguide to provide both structural support and electrical functionality for the sensor. A gap may be included between the handle and the diaphragm, allowing the diaphragm to move freely. An antenna and a ground plane may be formed on the diaphragm or the handle. Electromagnetic waves may be reflected off the antenna and detected to directly measure static and dynamic pressures applied to the diaphragm. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/014912 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 7/02 (20130101) B81B 2201/0264 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0143 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/148 (20130101) Original (OR) Class G01L 9/0042 (20130101) G01L 9/0047 (20130101) G01L 9/0073 (20130101) G01L 9/0077 (20130101) Antennas, i.e Radio Aerials H01Q 1/002 (20130101) H01Q 1/2208 (20130101) H01Q 9/0428 (20130101) H01Q 13/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794836 | Flynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Eric Flynn (Los Alamos, New Mexico); EliseAnne Koskelo (Los Alamos, New Mexico) |
| ABSTRACT | A system and method can include a laser Doppler vibrometer (LDV) in optical communication with a part during manufacturing and a transducer in ultrasonic communication with the part during manufacturing. The system can also include a controller connected to both the LDV and the transducer. The controller may be configured to cause the transducer to vibrate the part during manufacturing at a predetermined frequency and the LDV may be configured to measure one or more mechanical response types of the part during manufacturing based on one or more optical characteristics of a reflected beam. The controller may further be configured to determine whether a defect is present in the part during manufacturing in response to the one or more mechanical response types of the part. |
| FILED | Tuesday, December 26, 2017 |
| APPL NO | 15/854384 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02002 (20130101) G01B 9/02045 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 21/8806 (20130101) Original (OR) Class G01N 21/8851 (20130101) G01N 2021/8967 (20130101) G01N 2201/02 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794858 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | David Mathew Johnson (San Francisco, California); Jianer Bao (Sunnyvale, California); Martin J. Sheridan (Redwood City, California); Vedasri Vedharathinam (Sunnyvale, California); Christopher Paulson (Redwood City, California); Bhaskar Saha (Redwood City, California); Jessica Louis Baker Rivest (Palo Alto, California) |
| ABSTRACT | An electrochemical metal alloy identification device employing electrolytes to measure and identify different potentials of alloys is presented. This includes physical structure, disposables, electrical systems, control circuitry, and algorithms to identify alloys. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650003 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/276 (20200101) Alloys C22C 9/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/423 (20130101) G01N 27/4168 (20130101) Original (OR) Class G01N 33/2028 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794865 | Sinha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dipen N. Sinha (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus and method for the separation of an oil-water mixture into its components are described. An acoustic radiation force moves oil droplets to the nodes of an acoustic standing wave generated in a vertical column containing the oil-water mixture. Once the droplets are sufficiently close together, attractive forces become dominant and the droplets may coalesce to form larger droplets, which have greater buoyancy, and separation of the mixture into a layer of oil and a layer of water occurs, not possible by simple gravitational separation. Acoustically-driven oil-water separation may be used for water-cut measurements in oil production wells, since separation of the oil from the water permits accurate sound speed measurements to be made for both the oil and the water, thereby allowing frequent in situ calibrations of the apparatus to determine whether sound speed measurements on the mixture are accurate in the event that one or both of the mixture constituents is changing. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/563603 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/74 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/024 (20130101) Original (OR) Class G01N 2291/105 (20130101) G01N 2291/0222 (20130101) G01N 2291/0226 (20130101) G01N 2291/2634 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794915 | Marriott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); President and Board of Trustees of Santa Clara College (Santa Clara, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); PRESIDENT AND BOARD OF TRUSTEES OF SANTA CLARA COLLEGE (Santa Clara, California) |
| INVENTOR(S) | Gerard Marriott (Palo Alto, California); Alexander Chris Hoepker (Oakland, California); Yuling Yan (Oakland, California) |
| ABSTRACT | Isolated truncated and mutated sensor proteins derived from flavoproteins that are 12-20 KDa or less, genetically encoded for detection and imaging of protein complexes having long fluorescent lifetimes that can be 4.0 ns or greater. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/946461 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/28 (20130101) C07K 14/195 (20130101) C07K 14/415 (20130101) C07K 17/02 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795032 | Bizarri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gregory A. Bizarri (Berkeley, California); Edith D. Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California); Gautam Gundiah (Berkeley, California); Stephen M. Hanrahan (Berkeley, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising an optionally lanthanide-doped barium mixed halide, useful for detecting nuclear material. |
| FILED | Thursday, June 04, 2015 |
| APPL NO | 14/731302 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7733 (20130101) Measurement of Nuclear or X-radiation G01T 1/2023 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 4/00 (20130101) G21K 2004/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795103 | Rosenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Paul Kessler Rosenberg (Sunnyvale, California); Sagi Mathai (Sunnyvale, California); Michael Renne Ty Tan (Menlo Park, California) |
| ABSTRACT | Optoelectronic devices with a support member and methods of manufacturing or assembling the same are provided. An example of an optoelectronic device according to the present disclosure includes a substrate and an optical component and an electronic component disposed thereon or therein. The optoelectronic device further includes a ferrule coupled to the optical fiber and an optical socket receiving the ferrule therein. The optoelectronic device includes a support member disposed between the substrate and the optical socket such that the optical socket is spaced from the substrate by the support member. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175652 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/38 (20130101) G02B 6/422 (20130101) G02B 6/428 (20130101) Original (OR) Class G02B 6/4224 (20130101) G02B 6/4249 (20130101) G02B 6/4269 (20130101) G02B 6/4402 (20130101) G02B 6/4433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795815 | Beard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARM Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | ARM Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Jonathan Curtis Beard (Austin, Texas); Wendy Elsasser (Austin, Texas); Stephan Diestelhorst (Austin, Texas) |
| ABSTRACT | A data processing apparatus includes one or more host processors with first processing units, one or more caches with second processing unit, a non-cache memory having a third processing unit and a reorder buffer operable to maintain data order during execution of a program of instructions. An instruction scheduler routes instructions to the processing units. Data coherence is maintained by control logic that blocks access to data locations in use by a selected processing unit other than the selected processing unit until data associated with the data locations are released from the reorder buffer. Data stored in the cache is written to the memory if it is already in a modified state, otherwise the state is set to the modified state. A memory controller may be used to restrict access to memory locations to be operated on. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/166458 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3842 (20130101) G06F 12/08 (20130101) G06F 12/084 (20130101) G06F 12/0811 (20130101) G06F 12/0815 (20130101) Original (OR) Class G06F 15/7821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795825 | Tomei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| INVENTOR(S) | Matthew J. Tomei (Urbana-Champaign, Illinois); Philip B. Bedoukian (Ithaca, New York); Shomit N. Das (Austin, Texas) |
| ABSTRACT | An electronic device includes at least one compression-decompression functional block and a hierarchy of cache memories with a first cache memory and a second cache memory. The at least one compression-decompression functional block receives data in an uncompressed state, compresses the data using one of a first compression or a second compression, and, after compressing the data, provides the data to the first cache memory for storage therein. When the data is retrieved from the first cache memory to be stored in the second cache memory, when the data is compressed using the first compression, the compression-decompression functional block decompresses the data to reverse effects of the first compression on the data, thereby restoring the data to the uncompressed state and provides the data compressed using the second compression or in the uncompressed state to the second cache memory for storage therein. |
| FILED | Wednesday, December 26, 2018 |
| APPL NO | 16/232314 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0815 (20130101) G06F 12/0897 (20130101) Original (OR) Class G06F 2212/283 (20130101) G06F 2212/401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796252 | Werho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trevor N. Werho (Mesa, Arizona); Junshan Zhang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Trevor N. Werho (Mesa, Arizona); Junshan Zhang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
| ABSTRACT | Systems and methods for forecasting power generation in a wind farm are disclosed. The systems and methods utilize an induced Markov chain model to generate a forecast of power generation of the wind farm. The forecast is at least one of a point forecast or a distributional forecast. Additionally, the systems and methods modify at least one of: (i) a generation of electricity at a power plant coupled to a common power grid as the wind farm; or (ii) a distribution of electricity in the common power grid based on the forecast of power generation of the wind farm. In an exemplary approach, utilizing the induced Markov chain model to generate the forecast may include determining a series of time adjacent power output measurements based on historical wind power measurements and calculating a time series of difference values based on the series of time adjacent power output measurements. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/555490 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) Original (OR) Class G06Q 30/0283 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/386 (20130101) H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796258 | Hengartner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Nicolas Hengartner (Los Alamos, New Mexico); Leticia Cuellar-Hengartner (Los Alamos, New Mexico) |
| ABSTRACT | Effects in multiple linear regression may be decorrelated to decompose and attribute risk to common and proper effects. In other words, an attribute risk may be decomposed to two or more causes, where each cause is characterized by multiple attributes. The risk decomposition may decompose risk into a first residual part associated with a first set of risk factors, a second residual part associated with a second set of risk factors, and a common part associated with a set of common hidden variables that minimize a correlation between the first set of factors and the second set of factors. The common hidden variables may be modeled using a hidden factor model. An effect of the correlation may be minimized on the first set of risk factors and the second set of risk factors, and how correlated the terms of the risk decomposition are may be quantified. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103452 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) G06F 17/16 (20130101) G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0635 (20130101) Original (OR) Class G06Q 40/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796808 | Noel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NUSCALE POWER, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Derek Noel (Albany, Oregon) |
| ABSTRACT | A containment seal seals a cable or tube to an opening accessing a containment vessel. The containment seal includes a lower body that attaches over the opening into the containment vessel. The cable or tube is inserted through a hole that extends axially through an upper body of the containment seal. Compression fittings are attached to the top and bottom ends of the upper body sealing the cable inside of the upper body. The cable sealed inside of the upper body in inserted through the lower body and into the opening accessing the containment vessel and a lower portion of the upper body is seated into the opening formed in the lower body. A retaining device compresses the upper body down against the lower body forming a seal between the upper body and lower body. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/810976 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 5/02 (20130101) Nuclear Reactors G21C 13/036 (20130101) G21C 13/0285 (20130101) Original (OR) Class G21C 13/0675 (20130101) G21C 17/116 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 3/22 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10796874 — 3D printed micro channel plate, method of making and using 3D printed micro channel plate
| US 10796874 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Robert G. Wagner (Bolingbrook, Illinois); Michael J. Pellin (Naperville, Illinois); Howard Nicholson (South Hadley, Massachusetts); Lei Xia (Chicago, Illinois); Jingbo Wang (Willowbrook, Illinois); Junqi Xie (Naperville, Illinois); Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | The invention provides a gain device having a plurality of channels having a polygonal shape with four or more sides. The invention also provides a method for producing microchannel plates (MCPs) having the steps of providing a pre-polymer; and directing a laser over the pre-polymer into a pre-determined pattern. Also provided is method for efficiently 3D printing an object. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448313 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) B29C 64/268 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Electric Discharge Tubes or Discharge Lamps H01J 1/32 (20130101) Original (OR) Class H01J 9/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796907 | Eom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chang-Beom Eom (Madison, Wisconsin); Jungwoo Lee (Madison, Wisconsin) |
| ABSTRACT | Methods and systems for forming complex oxide films are provided. Also provided are complex oxide films and heterostructures made using the methods and electronic devices incorporating the complex oxide films and heterostructures. In the methods pulsed laser deposition is conducted in an atmosphere containing a metal-organic precursor to form highly stoichiometric complex oxides. |
| FILED | Monday, January 21, 2019 |
| APPL NO | 16/252783 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/28 (20130101) C23C 14/088 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02414 (20130101) H01L 21/02565 (20130101) Original (OR) Class H01L 21/02631 (20130101) H01L 29/24 (20130101) H01L 29/778 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797215 | Russ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boris Russ (Berkeley, California); David Brown (Washington, District of Columbia); Jared Lynch (Fremont, California); Tristan Day (Whittier, California); Nelson E. Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jason D. Forster (Berkeley, California); Jeffrey Snyder (Pasadena, California); Jeffrey J. Urban (Emeryville, California); Rachel A. Segalman (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Boris Russ (Berkeley, California); David Brown (Washington, District of Columbia); Jared Lynch (Fremont, California); Tristan Day (Whittier, California); Nelson E. Coates (Oakland, California); Ayaskanta Sahu (Berkeley, California); Jason D. Forster (Berkeley, California); Jeffrey Snyder (Pasadena, California); Jeffrey J. Urban (Emeryville, California); Rachel A. Segalman (Santa Barbara, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to graded thermoelectric materials. In one aspect, a method includes providing a plurality of nanostructures. The plurality of nanostructures comprise a thermoelectric material, with nanostructures of the plurality of nanostructures having first ligands disposed on surfaces of the nanostructures. The plurality of nanostructures is deposited on a substrate to form a layer. The layer is contacted with a solution containing second ligands. A ligand exchange process occurs where some of the first ligands disposed on the plurality of nanostructures are replaced with the second ligands. A first region of the layer is removed from contact with the solution so that the ligand exchange process does not occur in the first region of the layer, with the ligand exchange process occurring in the layer in contact with the solution. The layer is then removed from contact with the solution. |
| FILED | Thursday, September 01, 2016 |
| APPL NO | 15/254918 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) H01L 35/26 (20130101) Original (OR) Class H01L 35/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797288 | Carlson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OPTODOT CORPORATION (Devens, Massachusetts) |
| ASSIGNEE(S) | OPTODOT CORPORATION (Devens, Massachusetts) |
| INVENTOR(S) | Steven Allen Carlson (Cambridge, Massachusetts); Ifenna Kingsley Anakor (Allston, Massachusetts); Greg Robert Farrell (Sudbury, Massachusetts) |
| ABSTRACT | Provided are separators for use in an electrochemical cell comprising (a) an inorganic oxide and (b) an organic polymer, wherein the inorganic oxide comprises organic substituents. Also provided are electrochemical cells comprising such separators. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657257 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/303 (20130101) C04B 14/303 (20130101) C04B 24/00 (20130101) C04B 24/00 (20130101) C04B 24/023 (20130101) C04B 24/023 (20130101) C04B 26/06 (20130101) C04B 26/06 (20130101) C04B 38/0074 (20130101) C04B 38/0074 (20130101) C04B 2111/00612 (20130101) C04B 2111/00801 (20130101) C04B 2111/00853 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/16 (20130101) H01M 2/164 (20130101) H01M 2/166 (20130101) Original (OR) Class H01M 2/1646 (20130101) H01M 2/1653 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49115 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797349 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wildcat Discovery Technologies, Inc. (San Diego, California) |
| ASSIGNEE(S) | WILDCAT DISCOVERY TECHNOLOGIES, INC. (San Diego, California) |
| INVENTOR(S) | Ye Zhu (San Diego, California); Gang Cheng (San Diego, California); Deidre Strand (San Diego, California); Jen-Hsien Yang (San Diego, California) |
| ABSTRACT | Additives to electrolytes that enable the formation of comparatively more robust SEI films on silicon anodes. The SEI films in these embodiments are seen to be more robust in part because the batteries containing these materials have higher coulombic efficiency and longer cycle life than comparable batteries without such additives. The additives preferably contain a nitrate group. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186619 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797488 | Veda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Santosh Sambamoorthy Veda (Niskayuna, New York); William James Premerlani (Scotia, New York) |
| ABSTRACT | A method for operatively coupling a plurality of generating units in at least one micro-grid to a bulk grid, where the at least one micro-grid is configurable to be operatively coupled to the bulk grid via a point of interconnection breaker is presented. The method includes, using a control unit operatively coupled to the at least one micro-grid and the bulk grid, determining one or more bulk grid side parameters and one or more micro-grid side parameters, comparing one or more of the one or more micro-grid side parameters with corresponding one or more bulk grid side parameters, and synchronizing each of the plurality of generating units in the at least one micro-grid with the bulk grid based on the comparison. Further, the method includes connecting simultaneously, using the point of interconnection breaker, each of the plurality of generating units to the bulk grid based on the synchronization. |
| FILED | Tuesday, August 23, 2016 |
| APPL NO | 15/243974 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/04 (20130101) H02J 3/42 (20130101) H02J 3/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10791740 | Gokel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | George W. Gokel (Chesterfield, Missouri); Michael R. Gokel (Chesterfield, Missouri); Saeedeh Negin (St. Louis, Missouri); Mohit B. Patel (St. Louis, Missouri) |
| ABSTRACT | Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/316344 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/72 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/395 (20130101) A61K 31/496 (20130101) A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10791937 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lumicell, Inc. (Wellesley, Massachusetts) |
| ASSIGNEE(S) | Lumicell, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | W. David Lee (Brookline, Massachusetts); Jorge Ferrer (Arlington, Massachusetts); David B. Strasfeld (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/211201 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/0086 (20130101) A61B 5/0091 (20130101) Original (OR) Class A61B 5/4312 (20130101) A61B 5/6886 (20130101) A61B 10/0041 (20130101) A61B 90/361 (20160201) A61B 2090/306 (20160201) A61B 2090/309 (20160201) A61B 2090/3616 (20160201) A61B 2090/3941 (20160201) A61B 2505/05 (20130101) A61B 2560/0431 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792374 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Da Sun (Cleveland, Ohio) |
| ABSTRACT | A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or includes a polymer, a targeting group, or a detectable moiety, and at least one of R4 and R5 includes a targeting group that targets and/or binds to a retinal or visual protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/767119 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 48/0033 (20130101) Original (OR) Class A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Heterocyclic Compounds C07D 211/88 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792423 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Sanjian Chen (Philadelphia, Pennsylvania); James Erich Weimer (Philadelphia, Pennsylvania); Insup Lee (Newtown, Pennsylvania) |
| ABSTRACT | Methods, systems, and computer readable media for physiology parameter-invariant meal detection are disclosed. According to one system, the system includes at least one processor and a meal detection module implemented using the at least one processor. The meal detection module is configured to receive insulin intake information and blood glucose level information for a user, to detect a meal event using a physiology parameter-invariant meal detection algorithm, and after detecting the meal event, to perform at least one control action associated with insulin management. |
| FILED | Thursday, April 13, 2017 |
| APPL NO | 15/487179 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4839 (20130101) A61B 5/7275 (20130101) A61B 5/7282 (20130101) A61B 5/14532 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2005/14208 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/042 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792649 | Corgie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ZYMtronix, LLC (Ithaca, New York) |
| ASSIGNEE(S) | Zymtronix, LLC (Ithaca, New York) |
| INVENTOR(S) | Stephane Corgie (Ithaca, New York); Matthew Chun (Ithaca, New York); Ricki Chairil (El Monte, California); Rani Talal Brooks (Jefferson, Louisiana) |
| ABSTRACT | The present invention provides machines, compositions and methods for producing bionanocatalysts (BNCs) comprising one or more enzymes selected from a broad spectrum of industrially and medically important enzymes. The BNCs are self-assembled and magnetically immobilized enzymes. The machines, compositions, and methods are fully scalable from bench top to industrial manufacturing volumes. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/743999 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/02 (20130101) Original (OR) Class B01J 31/003 (20130101) B01J 35/0033 (20130101) B01J 37/0215 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 25/00 (20130101) B82Y 40/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) C12N 11/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792731 | Torabi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3DEO, Inc. (Gardena, California) |
| ASSIGNEE(S) | 3DEO, INC. (Gardena, California) |
| INVENTOR(S) | Payman Torabi (Los Angeles, California); Matthew Petros (Tarzana, California) |
| ABSTRACT | The present disclosure provides systems and methods for the formation of three-dimensional objects. A method for forming a three-dimensional object may comprise alternately and sequentially applying a stream comprising a binding substance to an area of a layer of powder material in a powder bed, and generating at least one perimeter of the three-dimensional object in the area. The stream may be applied in accordance with a model design of the three-dimensional object. The at least one perimeter may generated in accordance with the model design. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966742 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/008 (20130101) Original (OR) Class B22F 3/24 (20130101) B22F 2003/247 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10792807 | Lessing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Joshua Aaron Lessing (Cambridge, Massachusetts); Ramses V. Martinez (Madrid, Spain); Alok Suryavamsee Tayi (Somerville, Massachusetts); Jason Ming Ting (Katy, Texas); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A soft robot having an integrated electrical component includes an expandable or collapsible body, the body comprising an inlet that is configured to communicate with a fluid source and a flexible strain limited layer secured to a portion of the expandable or collapsible body, wherein the strain limited layer includes at least one electrical component. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/972412 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0012 (20130101) B25J 9/142 (20130101) Original (OR) Class B25J 13/08 (20130101) B25J 15/0009 (20130101) B25J 15/12 (20130101) B25J 18/06 (20130101) B25J 19/028 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793442 | Winter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Horst H. Winter (Amherst, Massachusetts); Wei Fan (Amherst, Massachusetts); Vijesh Tanna (Amherst, Massachusetts); Sanket Sabnis (Amherst, Massachusetts) |
| ABSTRACT | A method for forming zeolite nanosheets includes forming a mixture including a layered zeolite precursor and a functionalized polymer and exfoliating the layered zeolite precursor to provide the zeolite nanosheets. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/440704 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 37/0215 (20130101) B01J 2231/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/026 (20130101) Original (OR) Class C01B 39/48 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/24 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 9/04 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 9/00 (20130101) C08L 2666/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793449 | Westerhoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Kiril D. Hristovski (Gilbert, Arizona); Shahnawaz Sinha (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Kiril D. Hristovski (Gilbert, Arizona); Shahnawaz Sinha (Chandler, Arizona) |
| ABSTRACT | A reactor for water splitting or water treatment includes a first electrode, a second electrode electrically coupled to the first electrode, and a proton exchange membrane separating the first electrode and the second electrode. The first electrode includes a first optical fiber coated with a photocatalytic material. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499433 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/467 (20130101) Original (OR) Class C02F 3/005 (20130101) C02F 3/325 (20130101) C02F 2103/06 (20130101) C02F 2201/3222 (20130101) C02F 2201/46115 (20130101) C02F 2305/10 (20130101) C02F 2305/023 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2031 (20130101) H01G 9/2095 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793526 | Cai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jianfeng Cai (Tampa, Florida); Ma Su (Tampa, Florida); Alekhya Nimmagadda (Tampa, Florida); Peng Teng (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Jianfeng Cai (Tampa, Florida); Ma Su (Tampa, Florida); Alekhya Nimmagadda (Tampa, Florida); Peng Teng (Tampa, Florida) |
| ABSTRACT | The present disclosure provides compositions including a hydantoin derivative compound, pharmaceutical compositions including a hydantoin derivative compound, methods of treatment of a condition (e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540556 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4166 (20130101) Heterocyclic Compounds C07D 233/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793605 | Ly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Danith H. Ly (Pittsburgh, Pennsylvania); Srinivas Rapireddy (Pittsburgh, Pennsylvania); Bichismita Sahu (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362579 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793623 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Samuel Lai (Carrboro, North Carolina); M. Gregory Forest (Chapel Hill, North Carolina); Christine Henry (Chapel Hill, North Carolina); Timothy Wessler (Durham, North Carolina); Alexander Chen (Glenville, New York); Jennifer Schiller (Chapel Hill, North Carolina); Jay Newby (Carrboro, North Carolina) |
| ABSTRACT | The presently-disclosed subject matter relates to crosslinkers, compositions, and methods for trapping a target of interest on a substrate of interest. The methods may be used to inhibit and treat pathogen infection and provide contraception. The methods may be used to trap or separate particles and other substances. The subject matter further relates to methods of identifying and preparing optimal crosslinkers and methods for manipulating targets of interest. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977432 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 16/44 (20130101) C07K 16/087 (20130101) C07K 16/1045 (20130101) C07K 16/1235 (20130101) Original (OR) Class C07K 2317/41 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/557 (20130101) G01N 33/6854 (20130101) G01N 33/54346 (20130101) G01N 33/56983 (20130101) G01N 2333/16 (20130101) G01N 2333/4725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793673 | Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Nacu Hernandez (Ames, Iowa); Mengguo Yan (Ames, Iowa); Eric W. Cochran (Ames, Iowa); John Edward Matthiesen (Ames, Iowa); Jean-Philippe Tessonnier (Ames, Iowa) |
| ABSTRACT | The present invention relates to a polymer comprising a repeating group having the structure of formula (I) wherein R, R1, R2, R3, R4, X, and s are as described herein and salt thereof. Also disclosed is a process of synthesizing such polymers. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348561 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/26 (20130101) C08G 69/28 (20130101) C08G 69/48 (20130101) C08G 69/265 (20130101) Original (OR) Class C08G 77/455 (20130101) C08G 81/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793683 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Yufeng Wang (Hong Kong, China PRC); Michelle MacLeod (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides (block co-polymer)-(metal organic framework) conjugates (BCPMOFs), such as (block co-polymer)-(metal organic nanostructure) conjugates (BCPMONs), and thermoplastic elastomers, gels, and compositions thereof. Exemplary BCPMONs include (block co-polymer)-(metal organic cage) conjugates (BCPMOCs), (block co-polymer)-(metal organic paddlewheel) conjugates, and (block co-polymer)-(metal organic square) conjugates, such as BCPMONs of Formula (A), (B), or (C). Also described herein are macromonomers for preparing the BCPMONs; thermoplastic elastomers, gels, and compositions involving the BCPMONs; methods of preparing the BCPMONs, thermoplastic elastomers, gels, and compositions; and methods of using the BCPMONs, thermoplastic elastomers, gels, and compositions. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 15/662239 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/32 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) C07F 15/00 (20130101) C07F 15/0066 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/005 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/001 (20130101) C08G 83/008 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793713 | Robertson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Megan Robertson (Houston, Texas); Sheli Mauck (Houston, Texas); Shu Wang (Newark, Delaware) |
| ABSTRACT | Biorenewable additives or modifiers can be used for improving the performance of biorenewable thermoplastics. Modified natural oils, unmodified natural oils, and compatibilizers, as well as mixtures thereof, can be used in combination with a biorenewable thermoplastic such as polylactide (PLA) in order to produce an improved thermoplastic. Modified natural oils include acrylated epoxidized soybean oil (AESO), unmodified natural oils include unmodified soybean oil (SYBO), and the compatibilizers may be star polymer compatibilizers. The improved thermoplastic may have improved tensile properties with little plasticization. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/776196 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/101 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class C08L 67/04 (20130101) C08L 91/00 (20130101) C08L 91/00 (20130101) C08L 2201/06 (20130101) C08L 2205/03 (20130101) C08L 2205/08 (20130101) C08L 2205/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794029 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Ximin He (Tempe, Arizona); Edward Kavazanjian (Tempe, Arizona); Nasser Hamdan (Scottsdale, Arizona); Zhi Zhao (Mesa, Arizona) |
| ABSTRACT | A soil stabilization method of forming an admixture of at least one hydrogel precursor and urease enzyme, and contacting at least a portion of the admixture with soil, and forming a hydrogel network in-situ within at least a portion of the soil, wherein at least a portion of the hydrogel network includes in-situ precipitated calcium carbonate. In some embodiments, at least a portion of the hydrogel network is formed in-situ by polymerizing the at least one hydrogel precursor in the presence of the urease enzyme. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 16/077435 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/285 (20130101) C04B 24/14 (20130101) C04B 26/22 (20130101) C04B 26/285 (20130101) C04B 2103/0001 (20130101) C04B 2111/00146 (20130101) C04B 2111/00732 (20130101) Compositions of Macromolecular Compounds C08L 1/26 (20130101) C08L 5/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/22 (20130101) C09K 17/50 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 3/12 (20130101) Original (OR) Class Shafts; Tunnels; Galleries; Large Underground Chambers E21D 9/002 (20130101) E21D 9/0678 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794774 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yanfeng Jiang (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure describes various examples of spintronic temperature sensors. The example temperature sensors may be discrete or used to adaptively control operation of a component such as an integrated circuit (IC). In one example, an electronic device comprises a spintronic component configured such that the conductance of the spintronic component is based on sensed temperature. In one example, circuitry coupled to the spintronic component is configured to generate an electrical signal indicative of the sensed temperature based on the conductance of the spintronic component. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/828976 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/16 (20130101) G01K 7/36 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794921 | Ratner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Puget Sound Blood Center (Seattle, Washington) |
| INVENTOR(S) | Daniel M. Ratner (Seattle, Washington); Jill M. Johnsen (Seattle, Washington); James T. Kirk (Seattle, Washington); José A. López (Seattle, Washington); Norman D. Brault (Seattle, Washington); Shaoyi Jiang (Redmond, Washington) |
| ABSTRACT | Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047911 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/75 (20130101) G01N 21/7703 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794998 | Spuler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Scott Spuler (Westminster, Colorado); Matthew Hayman (Boulder, Colorado); Bruce Morley (Boulder, Colorado); Edwin W. Eloranta (Mount Horeb, Wisconsin) |
| ABSTRACT | Lidar is an acronym for Light Detection And Ranging. The technology may be used to measure distance by illuminating a target with a laser beam and performing analysis on the reflected laser beam light. In the atmospheric sciences, Lidar may be used to study the optical depth of clouds, the impact of aerosols on clouds, and the interactions between aerosols and clouds on the climate. The present application proposes a lidar-based technology using a diode laser (101) beam sent through a tapered semiconductor optical amplifier (106) and an axicon pair expander (108) wherein the laser light may be transmitted through a telescope (110) at an object to be studied. Upon striking the object to be studied, the laser (101) is reflected and recovered by the telescope (110). The reflected laser is then sent through a heated rubidium vapor cell (115) and a total detection channel (116) for analysis. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/090063 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/499 (20130101) G01S 7/4802 (20130101) Original (OR) Class G01S 7/4812 (20130101) G01S 7/4814 (20130101) G01S 7/4816 (20130101) G01S 17/95 (20130101) Optical Elements, Systems, or Apparatus G02B 27/126 (20130101) G02B 27/0972 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/50 (20130101) H01S 5/0064 (20130101) H01S 5/125 (20130101) H01S 5/0687 (20130101) Technologies for Adaptation to Climate Change Y02A 90/19 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795896 | Contractor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Noshir S. Contractor (Evanston, Illinois); Harshad E. Gado (Evanston, Illinois); Anup S. Sawant (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure include a system that automatically defines and assembles a group of users capable of solving a particular problem, such as problems associated with network platforms and infrastructures. The group of users are identified from user data captured while users interact within and throughout a network, such as a social network. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927721 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/248 (20190101) G06F 16/951 (20190101) G06F 16/24575 (20190101) G06F 16/24578 (20190101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 10/063112 (20130101) G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796104 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Andrew Lee (Ann Arbor, Michigan); Stefan Larson (Ann Arbor, Michigan); Christopher Clarke (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Michael A. Laurenzano (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Jason Mars (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for constructing an artificially diverse corpus of training data includes evaluating a corpus of utterance-based training data samples, identifying a slot replacement candidate; deriving distinct skeleton utterances that include the slot replacement candidate, wherein deriving the distinct skeleton utterances includes replacing slots of each of the plurality of distinct utterance training samples with one of a special token and proper slot classification labels; selecting a subset of the distinct skeleton utterances; converting each of the distinct skeleton utterances of the subset back to distinct utterance training samples while still maintaining the special token at a position of the slot replacement candidate; altering a percentage of the distinct utterance training samples with a distinct randomly-generated slot token value at the position of the slot replacement candidate; and constructing the artificially diverse corpus of training samples based on a collection of the percentage of the distinct utterance training samples. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/907792 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/35 (20200101) Original (OR) Class G06F 40/284 (20200101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796831 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Seok Kim (Champaign, Illinois); Zining Yang (Champaign, Illinois); Jun Kyu Park (Champaign, Illinois) |
| ABSTRACT | A magnetically-responsive surface structure comprises an array of hybrid microstructures on a substrate, where each hybrid microstructure comprises an elastomeric micropillar attached to the substrate and a rigid tile attached to the elastomeric micropillar. The rigid tiles collectively define a discontinuous, changeable surface. The hybrid microstructures further comprise a ferromagnetic material. The elastomeric micropillars are deflectable under a magnetic field so as to alter an orientation of the rigid tiles, thereby allowing a characteristic of the discontinuous, changeable surface to be manipulated. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/180204 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 26/02 (20130101) G02B 26/007 (20130101) G02B 26/023 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/081 (20130101) Original (OR) Class H01F 41/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796894 | Trimpin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (Philadelphia, Pennsylvania); WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| ASSIGNEE(S) | University Of The Sciences in Philadelphia (Philadelphia, Pennsylvania); Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Sarah Trimpin (Detroit, Michigan); Charles Nehemiah McEwen (Newark, Delaware); Vincent Salvatore Pagnotti (Moosic, Pennsylvania) |
| ABSTRACT | An ionizing system includes a channel and a heater coupled to the channel. The channel has an inlet disposed in a first pressure region having a first pressure and an outlet disposed in a second pressure region having a second pressure. The first pressure is greater than the second pressure. The heater is for heating the channel, and the channel is configured to generate charged particles of a sample in response to the sample being introduced into the channel. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/186763 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/10 (20130101) Original (OR) Class H01J 49/0404 (20130101) H01J 49/0468 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797537 | Chowdhury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Kaushik Chowdhury (Boston, Massachusetts); M. Yousof Naderi (Brookline, Massachusetts) |
| ABSTRACT | A distributed wireless radio frequency-based charging system includes hardware and software platforms. The hardware platform includes adaptive energy harvesters and programmable energy transmitters. The software platform manages the hardware profiles, resources (e.g., energy waveforms and transmission powers), schedules the beams of the energy transmitters, and switches between modes of wireless charging and data access point. This allows the energy transmitters to be configured adaptively based on the ambient energy availability, energy needs and number of energy-requesting devices in the network. Under the software control, the energy transmitters can cooperatively form focused beams of energy and power for transmission to energy harvesters in the energy-receiving devices, such as sensors, Internet of Things (IoT) enabled appliances, and mobile/wearable equipment. The energy harvesters can utilize the energy contained within the transmitted beams, as well as ambient RF sources, for directly powering their operation or charging a battery/capacitor for subsequent use. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 16/078742 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4257 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) H02J 7/025 (20130101) H02J 50/12 (20160201) H02J 50/80 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797760 | Natarajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Arun Natarajan (Corvallis, Oregon); Abhishek Agrawal (Corvallis, Oregon); Sanket Jain (Corvallis, Oregon); Robin Garg (Corvallis, Oregon) |
| ABSTRACT | An apparatus for simultaneous transmit and receive is provided. The apparatus is capable of rejecting or passing transmitter and receiver signals. The apparatus includes: a transmitter; an antenna (e.g., a shared antenna); a receiver including switches controllable by time varying signals; and a quadrature coupler including first, second, third, and fourth ports, wherein the first port is coupled to the transmitter, wherein the second port is coupled to the antenna, and wherein the third and fourth ports are coupled to the receiver. |
| FILED | Wednesday, April 18, 2018 |
| APPL NO | 15/956660 |
| ART UNIT | 2469 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 1/40 (20130101) H04B 7/0413 (20130101) Original (OR) Class H04B 7/2621 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/1461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797773 | Walling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Jeffrey Walling (Salt Lake City, Utah); Wen Yuan (Salt Lake City, Utah); Zhidong Bai (Salt Lake City, Utah); Ali Azam (Salt Lake City, Utah) |
| ABSTRACT | Embodiments of the disclosure are drawn to apparatuses and methods for transmission beamforming. A multiphase beam steering transmitter may include a transmitter array of multiple transmitters. A transmitter may include a multiphase logic decoder that directly controls a power amplifier to perform a vector addition of a beam phase and amplitude. A transmitter of the array may include a multiphase clock generator that outputs basis phases with embedded phase modulation data which are output to the multiphase logic decoder. The multiphase clock generator may receive a modulated clock signal. The PA may be a multiphase switched capacitor power amplifier. The multiphase logic decoder may output two phases adjacent to a desired phase as inputs to clocks of the SCPA. The multiphase logic decoder may further output a control signal that determines which cells in the SCPA are activated and when. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789098 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Amplifiers H03F 1/56 (20130101) H03F 3/005 (20130101) H03F 3/245 (20130101) H03F 2200/387 (20130101) H03F 2200/451 (20130101) Pulse Technique H03K 3/0315 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797926 | Walk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); Technische Universität Berlin (Berlin, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Technische Universität Berlin (Berlin, Germany) |
| INVENTOR(S) | Philipp Walk (Pasadena, California); Babak Hassibi (San Marino, California); Peter Jung (Berlin, Germany) |
| ABSTRACT | Systems and methods for transmitting data using various Modulation on Zeros schemes are described. In many embodiments, a communication system is utilized that includes a transmitter having a modulator that modulates a plurality of information bits to encode the bits in the zeros of the z-transform of a discrete-time baseband signal. In addition, the communication system includes a receiver having a decoder configured to decode a plurality of bits of information from the samples of a received signal by: determining a plurality of zeros of a z-transform of a received discrete-time baseband signal based upon samples from a received continuous-time signal, identifying zeros that encode the plurality of information bits, and outputting a plurality of decoded information bits based upon the identified zeros. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/260059 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Multiplex Communication H04J 11/00 (20130101) H04J 2011/0096 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0204 (20130101) H04L 27/2627 (20130101) Original (OR) Class H04L 27/2639 (20130101) H04L 27/2649 (20130101) H04L 27/2663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10792770 | Cleghorn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Geocent, LLC (Metairie, Louisiana); The USA as represented by Administrator of NASA (Huntsville, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Damon Max Hollis Cleghorn (Huntsville, Alabama); Justin Anderson Littell (Huntsville, Alabama) |
| ABSTRACT | A specialized vacuum chuck system of the present invention is capable of securing an object to a specialized welding tool in order to ensure that the object remains in a proper positional relationship with the welding tool. The system may also use springs and load stops to ensure that a proper load in maintained so the chuck base is not pulled off the object. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/204962 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Turning; Boring B23B 31/307 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/1295 (20130101) B23K 37/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793298 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Kelvin R. Garcia (Bethesda, Maryland); Thomas J. Hanyok (Clarksville, Maryland); Matthew S. Ashmore (Woodbine, Maryland) |
| ABSTRACT | Disclosed is a berthing system to receive a client module, including a plurality of berthing posts, a plurality of clamping mechanisms each mounted to a respective berthing post, the plurality of clamping mechanisms movable along a berthing post to clamp a received module, wherein the plurality of clamping mechanisms are configured to assert a radial force upon the received module, wherein the plurality of clamping mechanisms each include a rotary clamping jaw that includes drawdown portion and a radial contact portion. |
| FILED | Friday, February 16, 2018 |
| APPL NO | 15/898377 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/646 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794332 | Gagne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Kevin R. Gagne (Manchester, New Hampshire); Darren L. Hitt (Burlington, Vermont); Michael Ryan McDevitt (Burlington, Vermont) |
| ABSTRACT | Systems, apparatuses, and methods for generating hot gases based on catalyzation involving flowing catalyst. Catalysis occurs in a flow-type mixing catalyzation channel in which a liquid catalyst mixes with a liquid reactant flowing in a desired flow regime, such as a striated (laminar) flow regime or a slug flow regime. Devices such as micro-thrusters for satellite and other applications and hot gas generators for powering another device, such as an electrical generator, can be made using one or more flow-type mixing catalyzation channels. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354508 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/26 (20130101) B64G 1/401 (20130101) B64G 1/402 (20130101) Jet-propulsion Plants F02K 9/56 (20130101) Original (OR) Class F02K 9/88 (20130101) F02K 9/94 (20130101) F02K 9/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794371 | Vancil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | E BEAM INC. (Beaverton, Oregon) |
| ASSIGNEE(S) | E BEAM INC. (Beaverton, Oregon) |
| INVENTOR(S) | Bernard K Vancil (Beaverton, Oregon); Joseph Kowalski (Beaverton, Oregon); Jereme Shaver (Beaverton, Oregon) |
| ABSTRACT | Plasma cathodes for micro Hall and ion thrusters of unprecedented power efficiency, low cost, compactness, are provided. The cathodes employ, for example, a very small planar scandate cathode as electron source, delivering over 350 ma of discharge from an emitter area as small as only 0.012 cm2. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572304 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0012 (20130101) Original (OR) Class F03H 1/0087 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796037 | Trias |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Antonio Trias (Sant Cugat del Valles, Spain) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio Trias (Sant Cugat del Valles, Spain) |
| ABSTRACT | A system and method is presented for efficiently enforcing control limits in the calculation of powerflow studies of electrical power systems, using the Holomorphic Embedding Load-flow Method. The method applies to any automatic control in which the controlling resource is limited by a maximum or minimum value, such as Mvar limits in generators, the tap ratio in load-changing transformers, or real power output in AGC-participating generators. One key element of this invention consists in devising an equality constraint, holomorphically embedded, able to encode the switching behavior between the different control modes when limit thresholds are reached. The other key element is a novel analytic continuation scheme, here referred to as “Padé-Weierstrass”, which achieves the continuation to s=1 by means of several intermediate steps of power series re-expansions on the path from s=0 to s=1 in embedding parameter space. This technique exploits the great numerical stability of Padé approximants, which in the particular case of the power-flow problem have guaranteed convergence properties granted by Stahl's theorem. The Padé-Weierstrass technique provides the level of precision and numerical stability that is needed to perform the analytic continuation up to s=1 under the new equality constraint. The result is a greatly improved computational efficiency in the calculation of large powerflow studies in which control limits need to be enforced. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/838099 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/12 (20130101) G06F 30/20 (20200101) Original (OR) Class G06F 2111/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796585 | Greenwood |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Eric Greenwood (Newport News, Virginia) |
| ABSTRACT | A method and device provide a rotorcraft operator with real-time information concerning acoustic radiation on a region of the ground in the vicinity of the rotorcraft. A noise radiation model and at least one measured flight variable determine a high noise region on the ground that is bounded by a predefined noise level threshold. The method/device may include a display showing the high noise region and the position of the rotorcraft on a map. The rotorcraft operator may also be provided with real-time Blade-Vortex Interaction (“BVI”) avoidance guidance while the rotorcraft is in flight. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995563 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/001 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/00 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) G05D 1/0202 (20130101) G05D 1/0808 (20130101) Traffic Control Systems G08G 5/0021 (20130101) Original (OR) Class G08G 5/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796605 | Buras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tienovix, LLC (Houston, Texas) |
| ASSIGNEE(S) | Tienovix, LLC (Houston, Texas) |
| INVENTOR(S) | William R. Buras (Friendswood, Texas); Craig S. Russell (League City, Texas); Kyle Q. Nguyen (League City, Texas) |
| ABSTRACT | Methods for providing real-time, three-dimensional (3D) augmented reality (AR) feedback guidance to a user of an equipment system to achieve improved outcomes in the use of the equipment. The methods involve providing real-time real-time position-based 3D AR feedback and the real-time outcome-based 3D AR feedback to the user via an augmented reality user interface (ARUI). The feedback may be provided to the user via a head mounted display (HMD). |
| FILED | Thursday, December 26, 2019 |
| APPL NO | 16/727840 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/52 (20130101) A61B 8/085 (20130101) A61B 8/466 (20130101) A61B 8/467 (20130101) A61B 8/4245 (20130101) A61B 8/4254 (20130101) A61B 8/4263 (20130101) A61B 34/20 (20160201) A61B 90/361 (20160201) A61B 2034/2048 (20160201) A61B 2034/2055 (20160201) A61B 2090/365 (20160201) A61B 2090/378 (20160201) A61B 2090/3945 (20160201) A61B 2562/0219 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/016 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/065 (20130101) G09B 23/286 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10792649 | Corgie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ZYMtronix, LLC (Ithaca, New York) |
| ASSIGNEE(S) | Zymtronix, LLC (Ithaca, New York) |
| INVENTOR(S) | Stephane Corgie (Ithaca, New York); Matthew Chun (Ithaca, New York); Ricki Chairil (El Monte, California); Rani Talal Brooks (Jefferson, Louisiana) |
| ABSTRACT | The present invention provides machines, compositions and methods for producing bionanocatalysts (BNCs) comprising one or more enzymes selected from a broad spectrum of industrially and medically important enzymes. The BNCs are self-assembled and magnetically immobilized enzymes. The machines, compositions, and methods are fully scalable from bench top to industrial manufacturing volumes. |
| FILED | Friday, July 08, 2016 |
| APPL NO | 15/743999 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/02 (20130101) Original (OR) Class B01J 31/003 (20130101) B01J 35/0033 (20130101) B01J 37/0215 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 25/00 (20130101) B82Y 40/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) C12N 11/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793567 | Fuller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodin Therapeutics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided are compounds of the formula and pharmaceutically acceptable salts and composition thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g. HDAC2). |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 16/477466 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794332 | Gagne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Kevin R. Gagne (Manchester, New Hampshire); Darren L. Hitt (Burlington, Vermont); Michael Ryan McDevitt (Burlington, Vermont) |
| ABSTRACT | Systems, apparatuses, and methods for generating hot gases based on catalyzation involving flowing catalyst. Catalysis occurs in a flow-type mixing catalyzation channel in which a liquid catalyst mixes with a liquid reactant flowing in a desired flow regime, such as a striated (laminar) flow regime or a slug flow regime. Devices such as micro-thrusters for satellite and other applications and hot gas generators for powering another device, such as an electrical generator, can be made using one or more flow-type mixing catalyzation channels. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354508 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/26 (20130101) B64G 1/401 (20130101) B64G 1/402 (20130101) Jet-propulsion Plants F02K 9/56 (20130101) Original (OR) Class F02K 9/88 (20130101) F02K 9/94 (20130101) F02K 9/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796104 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Andrew Lee (Ann Arbor, Michigan); Stefan Larson (Ann Arbor, Michigan); Christopher Clarke (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Michael A. Laurenzano (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Jason Mars (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for constructing an artificially diverse corpus of training data includes evaluating a corpus of utterance-based training data samples, identifying a slot replacement candidate; deriving distinct skeleton utterances that include the slot replacement candidate, wherein deriving the distinct skeleton utterances includes replacing slots of each of the plurality of distinct utterance training samples with one of a special token and proper slot classification labels; selecting a subset of the distinct skeleton utterances; converting each of the distinct skeleton utterances of the subset back to distinct utterance training samples while still maintaining the special token at a position of the slot replacement candidate; altering a percentage of the distinct utterance training samples with a distinct randomly-generated slot token value at the position of the slot replacement candidate; and constructing the artificially diverse corpus of training samples based on a collection of the percentage of the distinct utterance training samples. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/907792 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/35 (20200101) Original (OR) Class G06F 40/284 (20200101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10794796 | Beaudoin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Stephen P Beaudoin (West Lafayette, Indiana); Bryan William Boudouris (Lafayette, Indiana); Michelle Chaffee-Cipich (Greenwood, Indiana); Aaron James Harrison (Aurora, Utah); Stefan Lukow (Washington, District of Columbia); Lizbeth Rostro (Lake Jackson, Texas); Caitlin Joy Schram (Troy, Michigan); Kathryn Maureen Smith (West Lafayette, Indiana); Myles Calvin Thomas (West Lafayette, Indiana) |
| ABSTRACT | A novel, advanced polymeric swab is disclosed herein. The swabs have a surface texture that allows for independent motion between microscale regions, are reusable with no loss of accuracy or efficiency, and are fabricated from optoelectronically-active elements to minimize static charging during repeated use. |
| FILED | Friday, September 18, 2015 |
| APPL NO | 14/858768 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) C08G 2261/93 (20130101) C08G 2261/94 (20130101) C08G 2261/512 (20130101) C08G 2261/592 (20130101) C08G 2261/1412 (20130101) C08G 2261/3223 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 33/227 (20130101) G01N 2001/022 (20130101) G01N 2001/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795032 | Bizarri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gregory A. Bizarri (Berkeley, California); Edith D. Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California); Gautam Gundiah (Berkeley, California); Stephen M. Hanrahan (Berkeley, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising an optionally lanthanide-doped barium mixed halide, useful for detecting nuclear material. |
| FILED | Thursday, June 04, 2015 |
| APPL NO | 14/731302 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7733 (20130101) Measurement of Nuclear or X-radiation G01T 1/2023 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 4/00 (20130101) G21K 2004/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10796544 | Fry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Atlantic City, New Jersey); Barry T. Smith (Atlantic City, New Jersey) |
| ABSTRACT | A method to analyze video includes obtaining an image series in an Eulerian or Lagrangian frame of reference, selecting one or more specific regions of interest and extracting to remove irrelevant motion and/or noise, decomposing the extracted images into a plurality of frequency bands and extracting a pixel value time series corresponding to the values of a pixel in each spatial frequency band, magnifying the pixel value time series to obtain a magnified pixel value time series, adding the magnified pixel value time series to the pixel value time series to generate a superimposed pixel value time series, and applying a spatial reconstruction to the superimposed pixel value time series to generate an output image series. A system to perform this method is also provided. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723168 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/20 (20130101) G06T 7/70 (20170101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19697 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 7/183 (20130101) H04N 7/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10795088 | Seyedi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Mir Ashkan Seyedi (Palo Alto, California); Chin-Hui Chen (Palo Alto, California) |
| ABSTRACT | In the examples provided herein, a system has a first racetrack resonant waveguide structure, positioned to enable an input light signal to couple from a first waveguide; and a second racetrack resonant waveguide structure, positioned to enable the input light signal to couple between the first racetrack resonant waveguide structure and the second racetrack resonant waveguide structure, and further positioned to enable an output light signal to couple from the second racetrack resonant waveguide structure to a second waveguide. The system also has a primary heating unit, positioned to heat a primary region including a first portion of the first racetrack resonant waveguide structure and a first portion of the second racetrack resonant waveguide structure, to change a central frequency and a passband width for the system. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/715455 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/20 (20130101) G02B 5/28 (20130101) G02B 6/293 (20130101) G02B 6/29343 (20130101) G02B 6/29389 (20130101) G02B 6/29395 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797194 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Xiaoge Zeng (Palo Alto, California); Zhihong Huang (Palo Alto, California); Di Liang (Santa Barbara, California) |
| ABSTRACT | A three-terminal avalanche photodiode provides a first controllable voltage drop across a light absorbing region and a second, independently controllable, voltage drop across a photocurrent amplifying region. The compositions of the absorbing region and the amplifying region may be optimized independently of each other. In the amplifying region, p-doped and n-doped structures are offset from each other both horizontally and vertically. Directly applying a voltage across a controlled region of the photocurrent path increases avalanche gain by shaping the electric field to overlap the photocurrent density. The resulting high-gain, low-bias avalanche photodiodes may be fabricated in integrated optical circuits using commercial CMOS processes, operated by power supplies common to mature computer architecture, and used for optical interconnects, light sensing, and other applications. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283224 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1129 (20130101) Original (OR) Class H01L 31/1804 (20130101) H01L 31/02027 (20130101) H01L 31/022408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797468 | Kurczveil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Geza Kurczveil (Santa Barbara, California); Di Liang (Santa Barbara, California); Raymond G. Beausoleil (Seattle, Washington) |
| ABSTRACT | Examples disclosed herein relate to multi-wavelength semiconductor lasers. In some examples disclosed herein, a multi-wavelength semiconductor laser may include a silicon-on-insulator (SOI) substrate and a quantum dot (QD) layer above the SOI substrate. The QD layer may include and active gain region and may have at least one angled junction at one end of the QD layer. The SOI substrate may include a waveguide in an upper silicon layer and a mode converter to facilitate optical coupling of a lasing mode to the waveguide. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/671303 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/50 (20130101) H01S 5/0208 (20130101) H01S 5/0601 (20130101) H01S 5/0602 (20130101) H01S 5/0651 (20130101) H01S 5/0657 (20130101) H01S 5/1003 (20130101) H01S 5/1014 (20130101) H01S 5/1032 (20130101) H01S 5/1067 (20130101) H01S 5/1071 (20130101) H01S 5/1092 (20130101) Original (OR) Class H01S 5/2224 (20130101) H01S 5/3412 (20130101) H01S 5/06817 (20130101) H01S 2301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10791722 | Hay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Bruce A. Hay (Encino, California); Omar S. Akbari (Pasadena, California); Anna B. Buchman (Pasadena, California) |
| ABSTRACT | Embodiments provided herein relate to systems for synthetically-engineered reciprocal chromosomal translocation for gene insertion into a population of organisms such as insects. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164452 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0339 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2227/706 (20130101) A01K 2267/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10793926 | St. John et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Franz St. John (Madison, Wisconsin); Diane Dietrich (Madison, Wisconsin); Merritt E. Casey Crooks (Madison, Wisconsin) |
| ABSTRACT | The invention provides a unique subset of GH30 subfamily 8 xylanases (GH30-8) with endo-β-1,4-xylanase activity, compositions comprising an effective amount of the GH30-8 xylanases, methods of synthesis and methods of use thereof. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/015408 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2482 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) Enzymes C12Y 302/01008 (20130101) Original (OR) Class Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 13/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10792107 | Hoffman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Brian D. Hoffman (Mountain View, California); David Q. Larkin (Menlo Park, California); Giuseppe Maria Prisco (Calci, Italy); Guanghua G. Zhang (San Jose, California); Rajesh Kumar (Sunnyvale, California) |
| ABSTRACT | Methods and system perform tool tracking during minimally invasive robotic surgery. Tool states are determined using triangulation techniques or a Bayesian filter from either or both non-endoscopically derived and endoscopically derived tool state information, or from either or both non-visually derived and visually derived tool state information. The non-endoscopically derived tool state information is derived from sensor data provided either by sensors associated with a mechanism for manipulating the tool, or sensors capable of detecting identifiable signals emanating or reflecting from the tool and indicative of its position, or external cameras viewing an end of the tool extending out of the body. The endoscopically derived tool state information is derived from image data provided by an endoscope inserted in the body so as to view the tool. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/371158 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/00193 (20130101) A61B 1/3132 (20130101) A61B 5/06 (20130101) A61B 5/061 (20130101) A61B 5/062 (20130101) A61B 5/725 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 34/30 (20160201) A61B 34/37 (20160201) A61B 90/36 (20160201) A61B 90/39 (20160201) A61B 90/361 (20160201) A61B 2034/102 (20160201) A61B 2034/2065 (20160201) A61B 2090/364 (20160201) A61B 2090/0818 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10797684 | Benz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Samuel Paul Benz (Superior, Colorado); Justus Albert Brevik (Boulder, Colorado); Manuel Angel Castellanos Beltran (Broomfield, Colorado); Paul David Dresselhaus (Louisville, Colorado); Peter Farrell Hopkins (Boulder, Colorado); Christine Annette Donnelly (Boulder, Colorado) |
| ABSTRACT | A superconducting waveform synthesizer produces an arbitrary waveform and includes an encoder that produces a bitstream; a pattern generator that produces a current bias pulse from the bitstream; a Josephson junction that produces a quantized output pulse from the current bias pulse; and a converter that produces an arbitrary waveform from the quantized output pulse. A process for producing an arbitrary waveform includes producing a bitstream; producing a current bias pulse from the bitstream; communicating the current bias pulse to a Josephson junction; producing, by the Josephson junction, a quantized output pulse from the current bias pulse; producing a quantized output pulse from the current bias pulse; and producing an arbitrary waveform from the quantized output pulse. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436062 |
| ART UNIT | 2849 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Pulse Technique H03K 3/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10794660 | Vabnick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE FEDERAL BUREAU OF INVESTIGATION, DEPARTMENT OF JUSTICE (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Quantico, Virginia) |
| ABSTRACT | Provided herein are fluid jet enhancement adapters for use with a propellant driven disrupter, and more particularly muzzle blast suppressor. The fluid jet enhancement muzzle blast suppressor may comprise a suppressor bore extending between the proximal end and the distal end with an inner suppressor surface that defines the suppressor bore. An outer suppressor surface opposably faces the inner suppressor surface, with a suppressor chamber positioned between the inner and outer suppressor surfaces. A plurality of passages connect the suppressor bore with the suppressor chamber, wherein the plurality of passages are sized to allow gas to move from the suppressor bore to the suppressor chamber and minimize liquid movement from the suppressor bore to the suppressor chamber. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366487 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/32 (20130101) Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 9/0046 (20130101) Original (OR) Class F41B 9/0075 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 33/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10794286 | Adibhatla |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Sridhar Adibhatla (Glendale, Ohio) |
| ABSTRACT | A method of modulating cooling flow to an engine component based on a health of the component is provided. The method includes determining a cooling flow requirement of the engine component for each of a plurality of operating conditions and channeling the determined required flow to the engine component during each respective operating condition of the plurality of operating conditions. The method also includes assessing a health of the engine component. The method further includes modifying the determined cooling flow requirement based on the assessed health of the engine component, and supplying the modified cooling flow requirement to the engine component during each subsequent respective operating condition of the plurality of operating conditions. |
| FILED | Tuesday, February 16, 2016 |
| APPL NO | 15/044475 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) Original (OR) Class F02C 9/00 (20130101) F02C 9/18 (20130101) Jet-propulsion Plants F02K 3/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/20 (20130101) F05D 2260/80 (20130101) F05D 2260/81 (20130101) F05D 2270/07 (20130101) F05D 2270/112 (20130101) F05D 2270/3062 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0289 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10792274 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jing Chen (Atlanta, Georgia); Jack Arbiser (Atlanta, Georgia); Brian Pollack (Decatur, Georgia); Siyuan Xia (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to methods of managing or treating cancer with agents that lower circulating acetoacetate levels, such as hypolipidemic agents, or other agents that antagonize acetoacetate-BRAF V600 mutant binding to attenuate BRAF V600 mutant tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of an agent to a subject in need thereof, wherein the agent is dehydroacetic acid, derivative, prodrug, or salt thereof. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386763 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10793840 | Tabor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jeffrey J. Tabor (Houston, Texas); Sebastian Schmidl (Houston, Texas); Ravi Sheth (Houston, Texas); Felix Ekness (Houston, Texas); Brian Landry (Houston, Texas); Nikola Dyuglyarov (Houston, Texas) |
| ABSTRACT | Methods to create two component signal transduction systems by replace the DNA binding domains and output promoters in bacteria are described. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/571744 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Original (OR) Class C12N 9/1229 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Enzymes C12Y 207/13003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 10792357 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York) |
| ASSIGNEE(S) | INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York) |
| INVENTOR(S) | Christopher L. Parks (New York, New York); Maoli Yuan (New York, New York); Xinsheng Zhang (New York, New York); Aaron Wilson (New York, New York); Angela Grazia Lombardo (New York, New York); Eddy Sayeed (New York, New York); Josephine Helena Cox (New York, New York); Takashi Hironaka (Ibaraki, Japan); Makoto Inoue (Ibaraki, Japan); Hiroto Hara (Ibaraki, Japan) |
| ABSTRACT | The present invention relates to a vector(s) containing and expressing an optimized HIV EnvF gene, methods for making the same and cell substrates qualified for vaccine production which may comprise vector(s) containing optimized HIV genes. |
| FILED | Monday, March 04, 2019 |
| APPL NO | 16/291073 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) A61K 2039/55511 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2740/16034 (20130101) C12N 2740/16134 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16334 (20130101) C12N 2760/18443 (20130101) C12N 2760/18843 (20130101) C12N 2760/18871 (20130101) C12N 2760/20243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10794200 | Simonds |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Mark E. Simonds (Cape Neddick, Maine) |
| ABSTRACT | A vane stage includes a ringcase extending circumferentially about a center axis of the vane stage. The ringcase extends completely about the center axis to form a first ring. An inner shroud extends circumferentially about the center axis of the vane stage. The inner shroud extends completely about the center axis to form a second ring positioned radially within the ringcase relative the center axis. A plurality of stationary half vanes extend radially between the ringcase and the inner shroud, and are circumferentially spaced about the center axis. The plurality of stationary half vanes are integral with the ringcase and the inner shroud. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/184632 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 9/044 (20130101) F01D 17/162 (20130101) F01D 25/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10794795 | Warren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Eli Cole Warren (Wethersfield, Connecticut); Michael F. Sabol (Port St. Lucie, Florida); Alan E. Ingram (Palm City, Florida); Michael J. Saitta (East Hampton, Connecticut); Darren M. Wind (Glastonbury, Connecticut); Steven D Mitchell (Port St. Lucie, Florida); Sebastian Martinez (Ivoryton, Connecticut); Kevin Andrew Ford (Killingworth, Connecticut); Patrick M. Harrington (West Hartford, Connecticut) |
| ABSTRACT | A low profile un-lensed non-intrusive stress measurement system probe may comprise a housing comprising a first channel and an optical face, a first hypotube disposed within the first channel and coupled at a sensing aperture in the optical face, and a plurality of optical fibers disposed within the first hypotube, wherein the first hypotube executes a bend between 45° and 90° within the housing. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/132128 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/00 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/80 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795453 | Powers |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Michael J. Powers (Amherst, New Hampshire) |
| ABSTRACT | Systems and methods for testing or correcting optical pointing systems are disclosed. An optical pointing system may include an imaging sensor including a field-of-view (FOV) carried by the optical pointing system, at least one collecting device for collecting optical photons and directing the optical photons to the imaging sensor, at least one directing device for directing the at least one collecting device to different pointing vectors, and at least one non-transitory computer-readable storage medium carried by the optical pointing system having instructions encoded thereon that when executed by at least one processor operates to test the optical pointing system by, inter alia, determining a pointing error based, at least in part, on a macro image of a targeted object. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047072 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0304 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/73 (20170101) Pictorial Communication, e.g Television H04N 5/341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10795466 | Lo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elysian Labs, Inc (Oakland, California) |
| ASSIGNEE(S) | Elysian Labs, Inc (Oakland, California) |
| INVENTOR(S) | Joanne Chung-Yan Lo (Oakland, California); Adam Patrick Hutz (El Cerrito, California) |
| ABSTRACT | An apparatus may include a transmitter capable of sending a signal to a device that is configured with an action module that interprets the signal and a programming module, a dial that is adjustable to a plurality of positions, where position is matched by the programming module with a programmable action, and a button that is communicatively coupled to the transmitter and that, when pressed, triggers the transmitter to send to the device the signal indicating the current position of the dial, such that the action module activates a programmable action associated with the current position of the dial in response to the button being pressed. Various other apparatuses, systems, and methods are also disclosed. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/973752 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0202 (20130101) G06F 3/0362 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 13/52 (20130101) H01H 19/005 (20130101) H01H 2013/525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 06, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201006.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page