FedInvent™ Patents
Patent Details for Tuesday, October 27, 2020
This page was updated on Monday, March 27, 2023 at 06:13 AM GMT
Department of Health and Human Services (HHS)
| US 10813342 | Maughan |
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| FUNDED BY |
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| APPLICANT(S) | Excet, Inc. (Springfield, Virginia) |
| ASSIGNEE(S) | Excet Incorporated (Springfield, Virginia) |
| INVENTOR(S) | Michele Nancy Maughan (Bear, Delaware) |
| ABSTRACT | Training aid delivery devices (TADDs) enabling the containment of training aid substances while allowing odor, in the form of volatile organic compounds (VOCs), to emanate freely out of the device have been developed. The use of one or more TADD in canine training are described. |
| FILED | Sunday, March 05, 2017 |
| APPL NO | 15/449971 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813549 | Lathrop et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kira Lynn Lathrop (Glenshaw, Pennsylvania); Joel Steven Schuman (Pittsburgh, Pennsylvania); Lawrence Edward Kagemann (Pittsburgh, Pennsylvania) |
| ABSTRACT | The innovation provides for a system and method available to image and visualize the palisades of Vogt via a non-contact process, analyze the image volumes acquired, evaluate the status of the palisades of Vogt from the data represented therein, and display the data in real-time or as a part of a medical record for ongoing consideration and evaluation. |
| FILED | Wednesday, January 03, 2018 |
| APPL NO | 15/861169 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/0041 (20130101) A61B 3/102 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813597 | Rice et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Covidien LP (Mansfield, Massachusetts) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); COVIDIEN LP (Mansfield, Massachusetts) |
| INVENTOR(S) | Tyler Bywaters Rice (Irvine, California); Michael Ghijsen (Irvine, California); Bruce J. Tromberg (Irvine, California); Bruce Yee Yang (Irvine, California); Sean Michael White (Irvine, California) |
| ABSTRACT | Systems and methods are disclosed for determining physiological information in a subject. The system includes: a light source positionable along a first location outside of the subject; a photo-sensitive detector positionable along a second location outside of the subject and configured to detect scattered light and generate a signal; a processor having a program and a memory, wherein the processor is operably coupled to the detector and configured to receive and store the signals generated over a period of time; wherein the processor is programmed to derive contrast metrics from the stored signals, calculate a waveform from the contrast metrics, decompose the waveform into basis functions and respective amplitudes, and compare the basis function amplitudes to determine the physiological information. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/488263 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/029 (20130101) A61B 5/0261 (20130101) A61B 5/726 (20130101) A61B 5/02007 (20130101) A61B 5/4875 (20130101) A61B 5/7257 (20130101) A61B 5/7278 (20130101) Original (OR) Class A61B 5/14551 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813698 | Trayanova et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Kathleen McDowell (Baltimore, Maryland) |
| ABSTRACT | Methods, system, and media for identifying one or more ablation locations in an atrial tissue region in an atrial fibrillation (AF) patient with atrial fibrosis are disclosed. Three-dimensional imaging data representing the atria of the patient may be received. A patient-specific model of the atria may be generated from the three-dimensional imaging data. Simulation of the AF on the patient-specific model may be conducted to identify AF-perpetrating regions. One or more ablation locations in the atria may be identified from the AF-perpetrating regions. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814053 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2018/00351 (20130101) A61B 2034/101 (20160201) A61B 2034/104 (20160201) A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813770 | Cavanagh et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Peter R. Cavanagh (Seattle, Washington); William R. Ledoux (Seattle, Washington); Bruce J. Sangeorzan (Seattle, Washington) |
| ABSTRACT | The present technology relates generally to devices and methods for arthroplasty procedures. In some embodiments, for example, a device is disclosed for use during an arthroplasty procedure of a joint of a patient, the joint extending between a first joint end of a first bone and an abutting second joint end of a second bone of the patient. The device includes an end plate configured and arranged for disposing over the first joint end of the first bone, a longitudinal plate extending from the end plate and configured and arranged for disposing along a medial, longitudinal surface of the first bone, and a stem extending from the end plate and suitable for extending along an intra-medullary canal of the first bone. When installed, at least one fastener extends at least partially through the first bone and couples the longitudinal plate to the first bone. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 15/542009 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/4225 (20130101) Original (OR) Class A61F 2002/4233 (20130101) A61F 2002/30578 (20130101) A61F 2002/30878 (20130101) A61F 2002/30902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813849 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Huakun Xu (Frederick, Maryland); Michael D. Weir (Silver Spring, Maryland); Ling Zhang (Shaanxi, China PRC) |
| ABSTRACT | The present invention provides rechargeable dental materials that can be widely applied in a variety of dental applications. The rechargeable dental materials of the invention may be included in dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is rechargeable with calcium and phosphate ions. The present invention also provides for a method of recharging the rechargeable dental material with calcium and phosphate ions. |
| FILED | Friday, February 05, 2016 |
| APPL NO | 15/017123 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/17 (20200101) A61K 6/62 (20200101) A61K 6/71 (20200101) A61K 6/77 (20200101) A61K 6/802 (20200101) A61K 6/838 (20200101) Original (OR) Class A61K 6/887 (20200101) A61K 6/887 (20200101) Compositions of Macromolecular Compounds C08L 33/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813894 | Hammock et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); Ahmet Bora Inceoglu (Davis, California); Fawaz G. Haj (Davis, California); Ahmed Bettaieb (Knoxville, Tennessee) |
| ABSTRACT | Provided are methods and compositions for preventing, reducing, mitigating and treating pain, particularly neuropathic pain by the combined administration of an agent that increases EETs and an agent that reduces/inhibits endoplasmic reticulum (ER) stress. |
| FILED | Thursday, February 11, 2016 |
| APPL NO | 15/551833 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/4468 (20130101) A61K 31/4468 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813905 | Ganapathy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Vadivel Ganapathy (Martinez, Georgia); Pamela M. Martin (Evans, Georgia) |
| ABSTRACT | Methods of using one or more fumaric acid esters or pharmacologically active salts, derivatives, analogues, or prodrugs thereof to increase expression of fetal hemoglobin (HbF) are disclosed. The methods typically include administering to a subject an effective amount of one or more fumaric acid esters optionally in combination or alternation with hydroxyurea to induce HbF expression in the subject in an effective amount to reduce one or more symptoms of a sickle cell disorder, a hemoglobinopathy, or a beta-thalassemia, or to compensate for a genetic mutation is the human beta-globin gene (HBB) or an expression control sequence thereof. Pharmaceutical dosage units and dosage regimes for use in the disclosed methods are also provided. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/666393 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/225 (20130101) Original (OR) Class A61K 31/225 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813915 | Cano et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Georgina Cano (Pittsburgh, Pennsylvania); Alan F. Sved (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to the use of an Angiotensin II type 1 (AT1) receptor blocker for promoting sleep and/or the treatment of insomnia. It is based, at least in part, on the results of experiments performed using a validated rat model of stress-induced insomnia in which candesartan was found to ameliorate sleep disturbances induced by stress. Further, it was observed that this effect seems to be caused by blockade of AT1 receptors located in several brain regions that are key components of the neural circuitry activated during insomnia. In contrast to currently marketed treatments for insomnia, the AT1 receptor blocker was found to restore normal sleep without inhibiting REM sleep and/or inducing atypical wave components in the EEG. |
| FILED | Thursday, July 24, 2014 |
| APPL NO | 14/340505 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 31/4178 (20130101) A61K 31/4184 (20130101) A61K 31/4245 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813917 | Sun et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zhaoli Sun (Perry Hall, Maryland); George Melville Williams (Arnold, Maryland) |
| ASSIGNEE(S) | MedRegen, LLC (Baltimore, Maryland) |
| INVENTOR(S) | Zhaoli Sun (Perry Hall, Maryland); George Melville Williams (Arnold, Maryland) |
| ABSTRACT | The present invention relates to the field of organ transplantation. In one aspect, the present invention provides methods of treating an organ transplant recipient comprising administering to the recipient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent. In particular embodiments, the present invention provides a method of treating an organ transplant recipient comprising administering to the recipient a therapeutically effective amount of an agent that mobilizes CD34+ and/or CD133+ stem cells and a low dose of an immunosuppressive agent. |
| FILED | Friday, December 10, 2010 |
| APPL NO | 13/515143 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/395 (20130101) A61K 31/436 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813922 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gong Chen (State College, Pennsylvania); Zheng Wu (State College, Pennsylvania); Ziyuan Guo (State College, Pennsylvania) |
| ABSTRACT | This document relates to methods and materials for reducing memory loss. For example, methods and materials for using inhibitors of GAT-3 polypeptide activity to reduce memory loss in mammals suffering from Alzheimer's disease are provided. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/026934 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/455 (20130101) Original (OR) Class A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/5517 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 51/0402 (20130101) A61K 51/0406 (20130101) A61K 51/1018 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/9426 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813927 | Sebti et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Said M. Sebti (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); James Turkson (Honolulu, Hawaii) |
| ABSTRACT | The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions. In one embodiment, a compound of the invention has the structure shown in formula I, formula II, or formula III. The subject invention also concerns methods of using the compounds and compositions of the invention. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978499 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) Original (OR) Class A61K 33/24 (20130101) Heterocyclic Compounds C07D 295/088 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813931 | Goldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Aaron Goldman (Somerville, Massachusetts); Ashish Kulkarni (Cambridge, Massachusetts); Shiladitya Sengupta (Waltham, Massachusetts) |
| ABSTRACT | The compositions and methods described herein relate to the treatment of cancer, e.g. by reducing the regression of cancer cells from regressing into cancer stem cell-like phenotypes and/or reducing the development of drug-resistant cancer cells. In some embodiments, the compositions and methods relate to inhibitors of PI3K pathway kinases and Src family kinases. |
| FILED | Wednesday, February 12, 2014 |
| APPL NO | 14/768230 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/6907 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813934 | Shenk et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Shenk (Princeton, New Jersey); Emre Koyuncu (Princeton, New Jersey); Ileana M. Cristea (Princeton, New Jersey) |
| ABSTRACT | Agents and methods of inhibiting or improving the growth of viruses are provided. |
| FILED | Monday, June 20, 2016 |
| APPL NO | 15/187269 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/40 (20130101) A61K 31/167 (20130101) A61K 31/366 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 31/498 (20130101) A61K 31/513 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813935 | Mohapatra et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); TRANSGENEX NANOBIOTECH, INC. (Lutz, Florida) |
| ASSIGNEE(S) | TRANSGENEX NANOBIOTECH, INC. (Lutz, Florida); University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Subhra Mohapatra (Lutz, Florida); Shyam S. Mohapatra (Lutz, Florida); Mark Howell (Tampa, Florida); Rajesh Nair (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine kinase inhibitors. The methods may include administering an anti-resistance agent such as a CYP51A1 inhibitor or an agonist of miRNA-764 (SEQ ID NO: 4) to a subject. A tyrosine kinase inhibitor may also be administered to the subject in addition to the anti-resistance agent. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/904176 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813949 | Delaney |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Colleen Delaney (Seattle, Washington) |
| ABSTRACT | Uses of expanded cord blood hematopoietic stem/progenitor cells (HSPC) are described. Examples include to reduce transplant rejection, to induce immune tolerance, to reduce total parenteral nutrition (TPN) feeding, opioid use, mucositis, and hospitalization following a medical procedure and to reduce graft versus host disease (GVHD) following an allogeneic transplant. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/781447 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 35/51 (20130101) A61K 39/001 (20130101) A61K 2035/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813952 | Childs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard W. Childs (Bethesda, Maryland); Mattias C.V. Carlsten (Bethesda, Maryland) |
| ABSTRACT | Disclosed herein are modified NK cells, compositions comprising modified NK cells, and methods for treating a tumor or hyperproliferative disease in a subject. In some embodiments, the modified NK cells include NK cells including a heterologous nucleic acid molecule encoding a CD16 protein comprising a valine at amino acid position 158 (CD16-V158), a heterologous nucleic acid molecule encoding a CCR7 protein, or both. In some embodiments, methods include treating a subject with a tumor by administering a composition comprising an anti-cancer monoclonal antibody and administering a composition comprising the modified NK cells to the subject. Also disclosed are methods of making modified NK cells by obtaining a population of NK cells from a subject and transfecting the population of NK cells with a heterologous nucleic acid molecule encoding CD16-V158, a heterologous nucleic acid molecule encoding a CCR7 protein, or both. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/525921 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/572 (20130101) A61K 2039/5156 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7158 (20130101) C07K 14/70535 (20130101) C07K 16/2887 (20130101) C07K 16/2896 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) C12N 2501/21 (20130101) C12N 2501/599 (20130101) C12N 2501/2302 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813956 | Kaznessis et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Yiannis J. Kaznessis (New Brighton, Minnesota); Katherine G. Volzing (Princeton, New Jersey); Juan Borrero Del Pino (Cork, Ireland); Gary Dunny (Minneapolis, Minnesota) |
| ABSTRACT | Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a pheromone-responsive region. In one embodiment, the pheromone-responsive region is derived from a conjugative plasmid from a member of the genus Enterococcus spp. The pheromone-responsive region includes a pheromone-responsive promoter and an operably linked coding region encoding an antimicrobial peptide. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a promoter and an operably linked coding sequence encoding an antimicrobial peptide, where expression of the coding region is controlled by a modulator polypeptide and is altered by a modulating agent, and where the coding region encodes an antimicrobial peptide. Also provided herein are methods of using the genetically modified microbes, including methods for inhibiting growth of an Enterococcus spp., a pathogenic E. coli, or a pathogenic Salmonella spp., for treating a subject, and for modifying a subject's gastrointestinal microflora. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894408 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/744 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 2035/11 (20130101) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813977 | Kumar-Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Rajendra Kumar-Singh (Boston, Massachusetts); Derek Leaderer (Boston, Massachusetts); Siobhan Cashman (Boston, Massachusetts) |
| ABSTRACT | Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/444500 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sanitary Equipment Not Otherwise Provided for; Toilet Accessories A47K 7/026 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) Cleaning in General; Prevention of Fouling in General B08B 7/02 (20130101) Handles for Hand Implements B25G 1/04 (20130101) B25G 1/06 (20130101) Peptides C07K 14/70596 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2333/4716 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813984 | Wands |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
| INVENTOR(S) | Jack R. Wands (East Greenwich, Rhode Island) |
| ABSTRACT | The present invention provides a peptide-based immunotherapy for ASPH-expressing tumors. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 14/696207 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12186 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) Enzymes C12Y 114/11016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813993 | Ramamurthi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kumaran S. Ramamurthi (North Potomac, Maryland); I-Lin Wu (Bethesda, Maryland) |
| ABSTRACT | A particle construct is disclosed that includes a synthetic core with a solid surface coated with a lipid bilayer, SpoVM adhered to the lipid bilayer; and SpoIVA adsorbed to the SpoVM. In additional embodiments, an agent of interest can be covalently linked to the SpoIVA. In specific, non-limiting examples, the agent of interest is an enzyme, a detectable marker, a pharmaceutical compound, an immunosuppressant or a vaccine. Methods of using the particle constructs are disclosed, such as for treating infections, treating a tumor, delivering a vaccine, treating an autoimmune disorder or ameliorating an allergic reaction. Method are also disclosed for degrading an environmental pollutant. Methods are also disclosed for producing these particle constructs. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 15/555283 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5015 (20130101) A61K 39/07 (20130101) A61K 39/385 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/55561 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/386 (20180101) Y02A 50/394 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814006 | Wiemer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); David F. Wiemer (Iowa City, Iowa); Rocky J. Barney (Iowa City, Iowa); Andrew Wiemer (Storrs, Connecticut) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | David F. Wiemer (Iowa City, Iowa); Rocky J. Barney (Iowa City, Iowa); Andrew Wiemer (Storrs, Connecticut) |
| ABSTRACT | The invention provides a drug conjugate comprising: 1) a therapeutic agent that comprises a phosphate, phosphonate, carboxy, or phosphoramidate group, and 2) a fluorescent group linked to the phosphate, phosphonate, carboxy, or phosphoramidate group to form the corresponding ester and salts thereof. The conjugates are useful for therapy and as probes. The invention also provides therapeutic methods for treating diseases with conjugates of the invention as well as methods for determining optimal dosages of a conjugate or a therapeutic agent for a given patient using a conjugate of the invention. |
| FILED | Thursday, July 14, 2016 |
| APPL NO | 15/745321 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/683 (20130101) A61K 41/0038 (20130101) A61K 47/545 (20170801) Original (OR) Class A61K 47/548 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5005 (20130101) G01N 33/5011 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814014 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jeffrey Roberts (Rockville, Maryland); Douglas R. Lowy (Bethesda, Maryland); John T. Schiller (Kensington, Maryland) |
| ABSTRACT | Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP). |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235152 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 31/7088 (20130101) A61K 35/76 (20130101) A61K 45/06 (20130101) A61K 47/6901 (20170801) A61K 49/0004 (20130101) Original (OR) Class A61K 49/0017 (20130101) A61K 49/0041 (20130101) A61K 49/0056 (20130101) A61K 49/0097 (20130101) A61K 49/0485 (20130101) A61K 51/1203 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20032 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/56983 (20130101) G01N 2333/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814015 | Dickey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Chad Dickey (Tampa, Florida); Bo Zhang (Tampa, Florida); Laura Jenelle Blair (Brandon, Florida) |
| ABSTRACT | The subject invention pertains to transgenic non-human animals comprising a transgenic nucleotide sequence, integrated into the genome of the animals, comprising a nucleotide sequence encoding human FKBP51 operably linked to a tetracycline response element. In some embodiments, the transgenic animal comprises an additional transgenic nucleotide sequence, integrated into the genome of the animal, comprising a nucleotide sequence encoding a tetracycline transactivator (tTA) operably linked to a promoter; wherein the tTA is expressed upon activation of the promoter and binds the tetracycline response element, thereby causing expression of FKBP51. The invention also pertains to methods for screening for agents for the prevention and/or treatment of psychiatric disorders, such as depression. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/602985 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2217/203 (20130101) A01K 2227/105 (20130101) A01K 2267/01 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0006 (20130101) Original (OR) Class A61K 49/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814020 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Jenny Jie Yang (Atlanta, Georgia); Fan Pu (Atlanta, Georgia); Shenghui Xue (Atlanta, Georgia); Jingjuan Qiao (Atlanta, Georgia); Mani Salarian (Atlanta, Georgia); Shanshan Tan (Atlanta, Georgia) |
| ABSTRACT | Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/572863 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/16 (20130101) A61K 49/126 (20130101) A61K 49/143 (20130101) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 99/006 (20130101) Peptides C07K 14/76 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814021 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Miqin Zhang (Seattle, Washington); Richard Revia (Seattle, Washington); Hui Wang (Seattle, Washington) |
| ABSTRACT | Boron-doped graphene quantum dots, methods for making the boron-doped graphene quantum dots, and methods for magnetic resonance imaging using the boron-doped graphene quantum dots. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222741 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/1824 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) C01B 32/174 (20170801) C01B 32/184 (20170801) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/51 (20130101) C01P 2006/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814032 | Khademhosseini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Ali Khademhosseini (Cambridge, Massachusetts); Nasim Annabi (Cambridge, Massachusetts); Alexander Assmann (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides an improved tissue adhesive to repair defects in soft tissue. Following ASTM standard tests, crosslinked methacryloyl-substituted gelatin hydrogels of the present invention (GelSEAL) were shown to exhibit adhesive properties, i.e. wound closure strength, shear resistance and burst pressure, that were superior to clinically used fibrin- and poly(ethylene glycol)-based glues. Chronic in vivo experiments in rats proved GelSEAL to effectively seal large lung leakages without additional sutures or staples, presenting improved performance as compared to fibrin and poly(ethylene glycol) glues. Furthermore, subcutaneous implantation in rats revealed high biocompatibility of GelSEAL as evidenced by low inflammatory host response. Advantageously, the tissue adhesives of the present invention are low cost and easy to produce, making them a promising substance to be used as a sealant for fluid leakages in soft tissue, as well as an easily tunable platform to further optimize the adhesive characteristics. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/502347 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/0015 (20130101) A61L 24/0031 (20130101) A61L 24/104 (20130101) Original (OR) Class A61L 2300/104 (20130101) A61L 2300/404 (20130101) A61L 2300/418 (20130101) A61L 2400/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814147 | Payne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Allison Payne (Salt Lake City, Utah); Rock J. Hadley (Salt Lake City, Utah); Robb P. Merrill (Salt Lake City, Utah); Emilee Minalga (Salt Lake City, Utah); Dennis L. Parker (Salt Lake City, Utah); Laura Lighty (Salt Lake City, Utah) |
| ABSTRACT | A therapeutic ultrasound breast treatment device (101) is disclosed. The device (101) can include a receptacle (130) to receive a breast of a patient therein. The device (101) can also include an ultrasound transducer assembly disposed proximate the receptacle and oriented to direct a high intensity ultrasound transmission through an opening (168) of the receptacle (130) toward the breast. The device (101) can include a liner (1 60) disposed in the receptacle (130) to contain an ultrasound coupling fluid about the breast. The liner (160) can have an extension portion that extends through the opening (168) to form a seal with the ultrasound transducer assembly to prevent leakage of the ultrasound coupling fluid. A focus location of the ultrasound transmission can be adjustable and the device (101) can include a plurality of RF tracking coils to determine the focus location of the ultrasound transmission to facilitate adjustment of the focus location in an MRI environment. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 15/318521 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4848 (20130101) A61B 8/406 (20130101) A61B 8/0825 (20130101) A61B 2017/2253 (20130101) A61B 2090/374 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/0091 (20130101) A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815203 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California); The University of Sydney (Sydney, Australia) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California); The University of Sydney (Sydney, New South Wales, Australia) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (San Diego, California); Annette Atkins (San Diego, California); Sungsoon Fang (La Jolla, California); Jae Myoung Suh (San Diego, California); Thomas J. Baiga (Escondido, California); Ruth T. Yu (La Jolla, California); John F. W. Keana (Eugene, Oregon); Christopher Liddle (Chertswood, Australia) |
| ABSTRACT | Novel compounds having a formula embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject. |
| FILED | Tuesday, September 10, 2019 |
| APPL NO | 16/566343 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 233/63 (20130101) C07C 2601/14 (20170501) C07C 2602/42 (20170501) Heterocyclic Compounds C07D 231/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815219 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Weidong Wang (Edmond, Oklahoma); Jae Wook Lee (Gangwon-do, South Korea) |
| ABSTRACT | Novel 2,4-diaminoquinazoline derivatives are disclosed. The compounds can be used in treating diseases and conditions which are associated with abnormal cell function related to endoplasmic reticulum (ER) stress. For example, the compounds can be used as suppressors of ER stress-induced pancreatic β-cell dysfunction and death, for example in the treatment of diabetes. |
| FILED | Friday, July 27, 2018 |
| APPL NO | 16/047372 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/51 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/00 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 403/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815271 | Eisenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | David S. Eisenberg (Los Angeles, California); Smriti Sangwan (Los Angeles, California); Lin Jiang (Santa Monica, California) |
| ABSTRACT | This invention relates to inhibitory peptides which bind to α-synuclein molecules and inhibit α-synuclein amyloidogenic aggregation, α-synuclein cytotoxicity, and spread of α-synuclein. Methods of making and using the inhibitory peptides (e.g. to treat subjects having conditions or diseases that are mediated by α-synuclein, such as Parkinson's disease, dementia with Lewy bodies, or MSA) are described. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 16/311593 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Peptides C07K 7/02 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/47 (20130101) C07K 14/4711 (20130101) C07K 2319/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815273 | Scheinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | David A. Scheinberg (New York, New York); Tao Dao (New York, New York) |
| ABSTRACT | This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT1-expressing cancer, comprising heteroclitic peptides derived from the WT-1 protein. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/920335 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/4748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815274 | O'Reilly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Richard O'Reilly (Roxbury, Connecticut); Ekaterina Doubrovina (West Orange, New Jersey); Annamalai Selvakumar (Bronx, New York) |
| ABSTRACT | This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/125213 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/001153 (20180801) A61K 2039/5158 (20130101) A61K 2039/55505 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) A61K 2039/55566 (20130101) A61K 2039/55577 (20130101) A61K 2039/55594 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815276 | Pei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Entrada Therapeutics, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Entrada Therapeutics, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dehua Pei (Columbus, Ohio); Ziqing Qian (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are compounds having activity as cell penetrating peptides. In some examples, the compounds can comprise a cell penetrating peptide moiety and a cargo moiety. The cargo moiety can comprise one or more detectable moieties, one or more therapeutic moieties, one or more targeting moieties, or any combination thereof. In some examples, the cell penetrating peptide moiety is cyclic. In some examples, the cell penetrating peptide moiety and cargo moiety together are cyclic. In some examples, the cell penetrating peptide moiety is cyclic and the cargo moiety is appended to the cyclic cell penetrating peptide moiety structure. In some examples, the cargo moiety is cyclic and the cell penetrating peptide moiety is cyclic, and together they form a fused bicyclic system. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360719 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/05 (20130101) A61K 38/12 (20130101) A61K 38/465 (20130101) A61K 47/64 (20170801) A61K 49/0039 (20130101) A61K 49/0041 (20130101) A61K 49/0043 (20130101) A61K 49/0047 (20130101) A61K 49/0056 (20130101) Peptides C07K 7/06 (20130101) C07K 7/64 (20130101) Original (OR) Class Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815279 | Srivastava et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Arun Srivastava (Gainesville, Florida); George Vladimirovich Aslanidi (Austin, Minnesota); Sergei Zolotukhin (Gainesville, Florida); Mavis Agbandje-McKenna (Gainesville, Florida); Kim M. Van Vliet (Gainesville, Florida); Li Zhong (Boxborough, Massachusetts); Lakshmanan Govindasamy (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations containing them. Also provided are methods of preparing and using the disclosed capsid-protein-mutated rAAV constructs in a variety of diagnostic and therapeutic modalities, including, inter alia, as mammalian cell-targeting delivery agents, and as human gene therapy vectors. Also disclosed are large-scale production methods for capsid-modified rAAV expression vectors, viral particles, and infectious virions having improved transduction efficiencies over those of the corresponding, un-modified, rAAV vectors, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/987993 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/42 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14171 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815290 | Gewe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Mesfin Gewe (Seattle, Washington); Roland K. Strong (Seattle, Washington); Martin Prlic (Seattle, Washington); Peter Rupert (Seattle, Washington); Thomas Spies (Seattle, Washington); Veronika Spies (Seattle, Washington) |
| ABSTRACT | Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands; (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions; and (iii) potentiate an immune response against a vaccine as well as many other potential uses. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/775298 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39 (20130101) A61K 2039/505 (20130101) A61K 2039/55516 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/47 (20130101) C07K 14/4705 (20130101) C07K 14/7056 (20130101) Original (OR) Class C07K 16/2833 (20130101) C07K 16/2851 (20130101) C07K 2317/76 (20130101) C07K 2319/00 (20130101) C07K 2319/43 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815295 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Methesda, Maryland) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Gary J. Nabel (Cambridge, Massachusetts); Rebecca S. Rudicell (Silver Spring, Maryland); John Mascola (Rockville, Maryland); Mark Connors (Bethesda, Maryland); Ivelin Georgiev (Nashville, Tennessee); Jiang Zhu (Ashburn, Virginia); Young Do Kwon (Rockville, Maryland); Tongqing Zhou (Boyds, Maryland); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Xueling Wu (Potomac, Maryland); Zhi-yong Yang (Potomac, Maryland); Wei Shi (Rockville, Maryland) |
| ABSTRACT | Monoclonal neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044083 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/41 (20130101) C07K 2317/56 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815301 | Kochenderfer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | Chimeric antigen receptors (CARs) that specifically bind to and immunologically recognize CD30 are disclosed. Related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs are also disclosed. Methods of treating or preventing a condition in a mammal, wherein the condition is cancer, are also disclosed. |
| FILED | Monday, October 10, 2016 |
| APPL NO | 15/766948 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 2317/53 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815457 | Kalinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEMS OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Pawel Kalinski (Wexford, Pennsylvania); Ravikumar Muthuswamy (Monroeville, Pennsylvania) |
| ABSTRACT | Provided herein are active CXCR4+ CD8+ T cells, active CXCR4+ type-1 CD4+ T cells and active CXCR4+ NK cells and populations of those cells, methods for making active CXCR4+ T cells and NK cells and populations of those cells, and methods for using active CXCR4+ T cells and NK cells and populations of those cells for the treatment of cancer, precancerous conditions and chronic infections. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 15/529124 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 5/0636 (20130101) C12N 5/0637 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2501/60 (20130101) C12N 2501/2312 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815458 | Stone |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Geoffrey William Stone (Coral Gables, Florida) |
| ABSTRACT | Compositions and methods of activating dendritic cells with LMP1 and LMP1-activated dendritic cell based compositions and methods are effective for dendritic cell therapy and provide an adjuvant function for vaccine administration. LMP1 or LMP1-CD40 chimeric protein may be used to activate and mature dendritic cells. LMP1 and LMP1-activated dendritic cells act as an adjuvant to enhance the cellular immune response. Also disclosed herein are kits for activating dendritic cells and for preparing a vaccine formulation. Administration of the dendritic cells transfected with LMP1 can induce an immune response against cancer or infection. The mature dendritic cells may comprise an antigen and at least one cytokine in addition to LMP1. Use of LMP1 or LMP1-CD40 provides a way to activate and mature dendritic cells that retain functional and migratory abilities without the side effects that result from maturing the dendritic cells using PGE2. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134745 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/15 (20130101) A61K 38/162 (20130101) A61K 38/162 (20130101) A61K 38/191 (20130101) A61K 38/191 (20130101) A61K 38/204 (20130101) A61K 38/204 (20130101) A61K 38/2006 (20130101) A61K 38/2006 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/245 (20130101) A61K 39/001129 (20180801) A61K 45/06 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) A61K 2039/55511 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70578 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 2510/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) C12N 2710/16244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815484 | Chinnaiyan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Arul Chinnaiyan (Ann Arbor, Michigan); Yasuyuki Hosono (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are compositions and methods for treating cancer. In particular, provided herein are compositions, methods, and uses of inhibitors of THOR for treating cancer. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/195185 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815486 | Niu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Great Falls, Virginia) |
| ABSTRACT | Disclosed is an RNA aptamer, a synthetic oligonucleotide of 2′-fluoro-modified A, U, and C nucleotides, with improved stability compared to its unmodified counterpart. Like the unmodified aptamer, however, the modified version is a potent glutamate receptor antagonist. Additionally, the RNA aptamers described herein are water soluble by nature, and generally exhibit nano- to micromolar potency making them potential therapeutic agents for the treatment of neurological disorders involving glutamate receptor activity. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028067 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 29/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815487 | Kochenderfer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683417 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815488 | Kochenderfer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683625 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815519 | Husain et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Naeem S Husain (Los Angeles, California); Harry Ming Tak Choi (Arcadia, California); Long Cai (Pasadena, California); Niles A Pierce (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods involving HCR reactions that involve using trigger oligos to activate probes that initiate HCR. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/689786 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/682 (20130101) C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6804 (20130101) C12Q 1/6825 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/536 (20130101) G01N 33/543 (20130101) G01N 33/54306 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815520 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Huang-Ge Zhang (Louisville, Kentucky) |
| ABSTRACT | Methods for diagnosis or prognosis of a cancer in a subject include isolating one or more nanovesicles from a biological sample obtained from the subject, determining the amount in the biological sample of the one or more nanovesicles, and comparing the amount of the one or more nanovesicles to a control level to thereby diagnose the cancer. The one or more nanovesicles are obtained by depleting the biological sample of exosomes prior to the isolation of the nanovesicles. Methods for identifying a tumor metastasis in a subject are also provided and include fractionating a biological sample from a subject to obtain a fraction including one or more exosomes and one or more nanovesicles having a diameter of about 8-12 nm, and then isolating the one or more nanovesicles to diagnose the tumor metastasis. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 15/948218 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/4833 (20130101) G01N 33/6848 (20130101) G01N 33/6893 (20130101) G01N 33/57484 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815522 | Velculescu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Victor Velculescu (Dayton, Maryland); Mark Sausen (Baltimore, Maryland); Vilmos Adleff (Baltimore, Maryland); Jillian Phallen (Baltimore, Maryland) |
| ABSTRACT | Pancreatic adenocarcinoma has the worst overall mortality of any solid tumor, with only 7% of patients surviving after 5 years. To evaluate the clinical implications of genomic alterations in this low cellularity tumor type, we deeply sequenced the genomes of 101 enriched pancreatic adenocarcinomas from patients who underwent potentially curative resections and used non-invasive approaches to examine tumor specific mutations in the circulation of these patients. These analyses revealed somatic mutations in chromatin regulating genes including MLL and ARID1A in 20% of patients that were associated with improved survival. Liquid biopsy analyses of cell free plasma DNA revealed that 43% of patients with localized disease had detectable circulating tumor DNA (ctDNA) in their blood at the time of diagnosis. Detection of ctDNA after resection predicted clinical relapse and poor outcome, and disease recurrence by ctDNA was detected 6.5 months earlier than with standard CT imaging. |
| FILED | Thursday, February 18, 2016 |
| APPL NO | 15/552076 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815523 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Gary P. Wang (Gainesville, Florida); Chak Kar (Eric) Li (Oviedo, Florida); Lin Liu (Gainesville, Florida) |
| ABSTRACT | The invention pertains to an assay that is capable of detecting a mutant polynucleotide in a plurality of polynucleotides. In one embodiment, the assay of the invention is capable of detecting one copy of a mutant polynucleotide in about 50,000 to about 100,000 copies of polynucleotides. The assay of the invention can be used to identify a mutant viral quasispecies or a mutant mRNA encoding an oncogenic protein from a tumor sample. The assay of the invention involves producing the single stranded complements of each of a plurality of polynucleotides containing the target sequence, wherein each of the single stranded complements contain a unique tag sequence and amplifying the single stranded complements by PCR using several sets of primers designed to introduce the sequences appropriate for a paired-end sequencing analysis of the amplified polynucleotides. The invention also pertains to kits for carrying out the assays of the invention. |
| FILED | Friday, December 23, 2016 |
| APPL NO | 16/067191 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/70 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6874 (20130101) C12Q 2525/15 (20130101) C12Q 2525/15 (20130101) C12Q 2525/15 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815526 | Lindsell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); Christopher John Lindsell (Cincinnati, Ohio) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| INVENTOR(S) | Christopher John Lindsell (Cincinnati, Ohio); Hector R. Wong (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction, particularly as those responses relate to septic shock in pediatric patients. In particular, the invention relates to identifying one or more biomarkers associated with septic shock in pediatric patients, obtaining a sample from a pediatric patient having at least one indication of septic shock, then quantifying from the sample an amount of one or more of said biomarkers, wherein the level of said biomarker correlates with a predicted outcome. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 15/038862 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815531 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Yan Zheng (Chicago, Illinois); Yuanyuan Zha (Chicago, Illinois); Robbert M. Spaapen (Chicago, Illinois); Thomas F. Gajewski (Chicago, Illinois) |
| ABSTRACT | Embodiments concern methods and composition related to anergic T-cells in patients, such as cancer patients. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937044 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) G01N 33/57484 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815536 | Lipkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Walter Ian Lipkin (New York, New York); Omar Jabado (Philadelphia, Pennsylvania); Thomas Briese (White Plains, New York); Amit Kapoor (Columbus, Ohio); Jan Gogarten (Berlin, Germany); Komal Jain (New York, New York); Nischay Mishra (New York, New York) |
| ABSTRACT | The present invention provides novel methods, systems, tools, and kits for the simultaneous detection, identification and/or characterization of all viruses known or suspected to infect vertebrates. The methods, systems, tools, and kits described herein are based upon the virome capture sequencing platform (“VirCapSeq-VERT”), a novel platform developed by the inventors. The invention also provides methods and kits for designing and constructing of the virome capture sequencing platform. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/759937 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1006 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class C12Q 2535/122 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 50/14 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816540 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Peter Tseng (Saratoga, California); Ivan Pushkarsky (San Diego, California) |
| ABSTRACT | A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584419 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/168 (20130101) B01L 2300/0654 (20130101) B01L 2300/0829 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/247 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 33/487 (20130101) G01N 33/582 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2021/6419 (20130101) G01N 2021/6441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816549 | Weinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Aaron Weinberg (Highland Heights, Ohio); Santosh Ghosh (Mayfield Heights, Ohio); Umut A. Gurkan (Cleveland, Ohio) |
| ABSTRACT | A method of detecting epithelial cancer is described that includes the steps of: (a) determining the level of beta defensin 3 (BD-3) and beta defensin 2 (BD-2) in a suspect sample obtained from a subject; (b) comparing the level of BD-3 to BD-2 determined in the suspect sample to obtain a suspect BD-3/BD-2 ratio, (c) comparing the suspect BD-3/BD-2 ratio to a healthy BD-3/BD-2 ratio to obtain a diagnostic BD-3/BD-2 ratio; and (d) characterizing the subject as having epithelial cancer if the diagnostic BD-3/BD-2 ratio is greater than 1. A microfluidic device for detecting epithelial cancer using the diagnostic BD-3/BD-2 ratio is also described. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/062175 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2200/027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) G01N 33/57407 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2333/4721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816550 | Cho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NANOCELLECT BIOMEDICAL, INC. (San Diego, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | NANOCELLECT BIOMEDICAL, INC. (San Diego, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Sung Hwan Cho (San Diego, California); Jose Morachis (San Diego, California); Yuhwa Lo (San Diego, California); Tsung-Feng Wu (San Diego, California); Ian Quigley (San Diego, California); Kendall Chuang (San Diego, California); Phillip Poonka (San Diego, California); William Alaynick (San Diego, California) |
| ABSTRACT | Provided here are cell detection systems, fluidic devices, structures and techniques related to particle and cell sorting and detection in fluid, for example sorting specific subpopulations of cell types. A method for verification of sorting of particles includes receiving a first detection signal that is associated with optical characteristics of a particle in a first channel. A sorting channel of a plurality of second channels is determined based on the first detection signal, thereby determining the sorting of the particle into the sorting channel based on the optical characteristics of the particle. A sorting signal for sorting the particle from the first channel into the sorting channel is transmitted. A second detection signal is received that is associated with the presence of the particle in the sorting channel. The sorting of the particle from the first channel into the sorting channel is verified based on the second detection signal. |
| FILED | Tuesday, October 15, 2013 |
| APPL NO | 14/435710 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/087 (20130101) B01L 2300/088 (20130101) B01L 2300/0636 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 21/6486 (20130101) G01N 33/582 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2015/1075 (20130101) G01N 2015/1081 (20130101) G01N 2015/1486 (20130101) G01N 2201/06113 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816554 | Birnbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michael Edward Birnbaum (Stanford, California); Juan Luis Mendoza (Redwood City, California); Michael Thomas Bethune (Pasadena, California); David Baltimore (Pasadena, California); Kenan Christopher Garcia (Menlo Park, California) |
| ABSTRACT | Compositions and methods are provided for the identification of peptide sequences that are ligands for a T cell receptor (TCR) of interest, in a given MHC context. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 15/301930 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2333/7051 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818073 | Mistretta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Charles A. Mistretta (Madison, Wisconsin); Charles M. Strother (Madison, Wisconsin) |
| ABSTRACT | A system and method are provided for generating time resolved series of angiographic volume data having flow information integrated therewith. The method includes generating a series of 3D time-resolved vascular volumes from time resolved x-ray projection data and calculating blood velocity in the vascular volumes x-ray projection data to determine a rate of change of calculated contrast material arrival time at positions along the vascular volumes. The method also includes displaying the 3D time-resolved vascular volumes with a graphical indication of blood velocity in the vascular volumes. |
| FILED | Tuesday, March 10, 2015 |
| APPL NO | 14/643853 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0263 (20130101) A61B 5/0275 (20130101) A61B 6/463 (20130101) A61B 6/466 (20130101) A61B 6/481 (20130101) A61B 6/486 (20130101) A61B 6/504 (20130101) A61B 6/507 (20130101) A61B 6/4441 (20130101) A61B 6/5217 (20130101) A61B 6/5235 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) G06T 7/248 (20170101) G06T 15/08 (20130101) Original (OR) Class G06T 2207/10076 (20130101) G06T 2207/10116 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818398 | Abou Shousha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Mohamed Abou Shousha (Pembroke Pines, Florida); Amr Saad Mohamed Elsawy (South Miami, Florida) |
| ABSTRACT | In some embodiments, a set of eye images related to a subject may be provided to a prediction model. A first prediction may be obtained via the prediction model, where the first prediction is derived from a first eye image and indicates whether an eye condition is present in the subject. A second prediction may be obtained via the prediction model, where the second prediction is derived from a second eye image and indicates that the eye condition is present in the subject. An aspect associated with the first prediction may be adjusted via the prediction model based on the second prediction's indication that the eye condition is present in the subject. One or more predictions related to at least one eye condition for the subject may be obtained from the prediction model, where the prediction model generates the predictions based on the adjustment of the first prediction. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524715 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/0058 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/30041 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10813342 | Maughan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Excet, Inc. (Springfield, Virginia) |
| ASSIGNEE(S) | Excet Incorporated (Springfield, Virginia) |
| INVENTOR(S) | Michele Nancy Maughan (Bear, Delaware) |
| ABSTRACT | Training aid delivery devices (TADDs) enabling the containment of training aid substances while allowing odor, in the form of volatile organic compounds (VOCs), to emanate freely out of the device have been developed. The use of one or more TADD in canine training are described. |
| FILED | Sunday, March 05, 2017 |
| APPL NO | 15/449971 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813581 | Hartings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| INVENTOR(S) | Jed A. Hartings (Cincinnati, Ohio); Jonathan Adam Wilson (Cincinnati, Ohio) |
| ABSTRACT | Computer-implemented methods and automated systems for real-time detection of spreading depolarizations in a brain injured patient, based an algorithm of (a) providing a reference data base of spreading depolarization waveform templates generated from EEG recordings of confirmed spreading depolarizations (SD) in a reference brain-injured patient cohort; (b) recording an EEG of the brain injured patient to generate recorded EEG waveforms; (c) detecting a slow potential change present in a recorded EEG waveform by applying a power spectral density estimate to the recorded waveform; (d) comparing a detected SPC to a reference database of SD waveform template to identify a candidate SD; and (e) rejecting a candidate SD as a false positive based on overall signal power and amplitude analysis and identifying a non-rejected candidate SD as a detected SD. |
| FILED | Tuesday, June 30, 2015 |
| APPL NO | 15/562922 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/048 (20130101) A61B 5/0476 (20130101) A61B 5/742 (20130101) A61B 5/743 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/7246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813904 | Law et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Brian Keith Law (Gainesville, Florida); Ronald K. Castellano (Gainesville, Florida); Renan B. Ferreira (Gainesville, Florida) |
| ABSTRACT | The invention relates to methods of treating cell proliferative disorders. The invention further relates to pharmaceutical compositions for treating cell proliferative disorders, especially cancer. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 16/487304 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 39/3955 (20130101) Acyclic or Carbocyclic Compounds C07C 323/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813931 | Goldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Aaron Goldman (Somerville, Massachusetts); Ashish Kulkarni (Cambridge, Massachusetts); Shiladitya Sengupta (Waltham, Massachusetts) |
| ABSTRACT | The compositions and methods described herein relate to the treatment of cancer, e.g. by reducing the regression of cancer cells from regressing into cancer stem cell-like phenotypes and/or reducing the development of drug-resistant cancer cells. In some embodiments, the compositions and methods relate to inhibitors of PI3K pathway kinases and Src family kinases. |
| FILED | Wednesday, February 12, 2014 |
| APPL NO | 14/768230 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/6907 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813988 | Super et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Super (Lexington, Massachusetts); Edward J. Doherty (Mansfield, Massachusetts); Mark Cartwright (West Newton, Massachusetts); Des White (Boston, Massachusetts); Alexander G. Stafford (Revere, Massachusetts); Omar Abdel-Rahman Ali (Cambridge, Massachusetts); Amanda Graveline (Boston, Massachusetts); Donald E. Ingber (Boston, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Benjamin Seiler (Boston, Massachusetts) |
| ABSTRACT | The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/434781 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/025 (20130101) A61K 39/0258 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) Technologies for Adaptation to Climate Change Y02A 50/474 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814119 | Donaldson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Critical Innovations, LLC (Inglewood, California) |
| ASSIGNEE(S) | CRITICAL INNOVATIONS, LLC (Inglewood, California) |
| INVENTOR(S) | Ross I. Donaldson (Inglewood, California); Oliver Buchanan (Inglewood, California); Tim Fisher (Inglewood, California); Jon Armstrong (Inglewood, California); John Cambridge (Inglewood, California) |
| ABSTRACT | An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway and attachment device. The provided assembly substantially reduces the possibility of iatrogenic infection while accessing and/or re-accessing a body space. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113707 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/34 (20130101) A61B 17/3415 (20130101) A61B 17/3423 (20130101) A61B 17/3498 (20130101) A61B 90/40 (20160201) A61B 2017/345 (20130101) A61B 2017/00809 (20130101) A61B 2017/3492 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/02 (20130101) A61M 27/00 (20130101) A61M 39/0247 (20130101) Original (OR) Class A61M 2039/027 (20130101) A61M 2039/0252 (20130101) A61M 2039/0258 (20130101) A61M 2039/0261 (20130101) A61M 2039/0276 (20130101) A61M 2039/0279 (20130101) A61M 2039/0288 (20130101) A61M 2210/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814323 | Ingber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Daniel Levner (Cambridge, Massachusetts); Guy Thompson, II (Lexington, Massachusetts); Christopher David Hinojosa (Cambridge, Massachusetts) |
| ABSTRACT | According to aspects of the present invention, a cartridge assembly for transporting fluid into or out of one or more fluidic devices includes a first layer and a second layer. The first layer includes a first surface. The first surface includes at least one partial channel disposed thereon. The second layer abuts the first surface, thereby forming a channel from the at least one partial channel. At least one of the first layer and the second layer is a resilient layer formed from a pliable material. At least one of the first layer and the second layer includes a via hole. The via hole is aligned with the channel to pass fluid thereto. The via hole is configured to pass fluid through the first layer or the second layer substantially perpendicularly to the channel. Embossments are also used to define aspects of a fluidic channel. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/379443 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/56 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/027 (20130101) B01L 2200/0684 (20130101) B01L 2200/0689 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0874 (20130101) B01L 2300/0887 (20130101) B01L 2400/0481 (20130101) B01L 2400/0655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814327 | Glezer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Eli N. Glezer (Del Mar, California); Stephen Higgins (Geithersburg, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gatihersburg, Maryland); Kenneth Page (Germantown, Maryland); Kristian Roth (Germantown, Maryland); George Sigal (Rockville, Maryland) |
| ABSTRACT | Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge. |
| FILED | Tuesday, July 11, 2017 |
| APPL NO | 15/646578 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/146 (20130101) B01L 2200/0605 (20130101) B01L 2200/0621 (20130101) B01L 2200/0631 (20130101) B01L 2300/087 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2400/0487 (20130101) B01L 2400/0688 (20130101) B01L 2400/0694 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814609 | Ehrenberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Isaac Mayer Ehrenberg (Brookline, Massachusetts) |
| ABSTRACT | Systems and methods for producing electromagnetic devices are provided. The systems and methods allow for an electromagnetic device having both a substrate (e.g., polymer) and conductive material (e.g., metal) to be manufactured without using masks or other outside objects disposed over a surface (e.g., the substrate) onto which the conductive material is deposited. In one exemplary embodiment, the method includes performing additive manufacturing using a polymer to produce a device having a plurality of interconnected walls and a plurality of frequency selective surface elements, and then coating portions of the device with a conductive material. A plurality of shadowing features are formed as part of one or more of the walls to protect the frequency selective surface elements from being coated by the conductive material. Other methods, and a variety of systems that can result from the disclosed methods, are also provided. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 15/462798 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/20 (20130101) C23C 14/044 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/146 (20130101) H05K 3/1258 (20130101) H05K 2201/09036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815125 | Gopalan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Padma Gopalan (Madison, Wisconsin); Michael Scott Arnold (Middleton, Wisconsin); Catherine Kanimozhi Kansiusarulsamy (Madison, Wisconsin); Matthew John Shea (Madison, Wisconsin) |
| ABSTRACT | Polymers having pendant polycyclic aromatic hydrocarbon (PAH) groups covalently bound to the polymer backbone via thioester bonds are provided. The PAH groups are covalently bound to the backbone of the polymer by a molecular linker that includes a thioester bond. Also provided are dispersions of polymer-coated carbon nanotubes and carbon nanotube films formed from the dispersions. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863087 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) B05D 3/107 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Original (OR) Class C01B 2202/02 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 293/005 (20130101) C08F 2438/03 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/008 (20130101) C09D 5/20 (20130101) C09D 7/65 (20180101) C09D 153/005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/746 (20130101) Y10S 977/845 (20130101) Y10S 977/847 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815486 | Niu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Great Falls, Virginia) |
| ABSTRACT | Disclosed is an RNA aptamer, a synthetic oligonucleotide of 2′-fluoro-modified A, U, and C nucleotides, with improved stability compared to its unmodified counterpart. Like the unmodified aptamer, however, the modified version is a potent glutamate receptor antagonist. Additionally, the RNA aptamers described herein are water soluble by nature, and generally exhibit nano- to micromolar potency making them potential therapeutic agents for the treatment of neurological disorders involving glutamate receptor activity. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028067 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 29/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815519 | Husain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Naeem S Husain (Los Angeles, California); Harry Ming Tak Choi (Arcadia, California); Long Cai (Pasadena, California); Niles A Pierce (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods involving HCR reactions that involve using trigger oligos to activate probes that initiate HCR. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/689786 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/682 (20130101) C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6804 (20130101) C12Q 1/6825 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/536 (20130101) G01N 33/543 (20130101) G01N 33/54306 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815581 | Woodrow |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Thomas A. Woodrow (Lakeside, Texas) |
| ABSTRACT | Systems and methods for tin antimony plating are provided. One plating method includes doping a tin (Sn) plating solution with antimony (Sb). One method also includes electroplating a component using the antimony-doped tin plating. The antimony-doped tin plating formed by one method includes between about 1% and about 3% antimony. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/127105 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/32 (20130101) C25D 3/60 (20130101) Original (OR) Class C25D 21/02 (20130101) C25D 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815813 | Blaney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Ken F. Blaney (Middleton, New Hampshire); Christopher M. Jarochym (Ogunquit, Maine) |
| ABSTRACT | An active clearance control system for a gas turbine engine includes an annular piston with a multiple of piston lift lugs. A method of active blade tip clearance control for a gas turbine engine includes translating axial movement of an annular piston to radial movement of a multiple of blade outer air seal segments. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/903836 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 5/12 (20130101) F01D 11/20 (20130101) Original (OR) Class F01D 11/22 (20130101) F01D 25/246 (20130101) Non-positive-displacement Pumps F04D 27/002 (20130101) F04D 29/164 (20130101) F04D 29/324 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2250/232 (20130101) F05D 2260/56 (20130101) F05D 2260/57 (20130101) F05D 2270/64 (20130101) F05D 2270/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815815 | Duguay |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Brian Duguay (Berwick, Maine) |
| ABSTRACT | A method of actuating a Blade Outer Air Seal (BOAS) includes moving a retractor against a portion of a BOAS segment to move the BOAS segment from a first position to a second position that is radially outside the first position. The BOAS segment is seated against a support structure when in the first position and spaced from the support structure when in the second position. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031537 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) F01D 11/20 (20130101) Original (OR) Class F01D 11/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) F05D 2240/55 (20130101) F05D 2260/57 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815818 | Propheter-Hinckley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut); Raymond Surace (Newington, Connecticut); Robert L. Hazzard (Windsor, Connecticut); Mark Borja (Palm Beach Gardens, Florida) |
| ABSTRACT | A variable-pitch vane assembly for a gas turbine engine includes a sync ring, a vane having a vane arm, and a pin installed through the sync ring and through the vane arm. The pin includes an anti-rotation notch located along a pin shaft. An anti-rotation spacer is engaged with the pin at the anti-rotation notch to prevent rotation of the pin. A turbine section of a gas turbine engine includes a turbine rotor and a turbine stator. The turbine stator includes one or more variable-pitch vane assemblies including a sync ring, a vane having a vane arm, and a pin installed through the sync ring and through the vane arm. The pin includes an anti-rotation notch located along a pin shaft. An anti-rotation spacer is engaged with the pin at the anti-rotation notch to prevent rotation of the pin. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/653064 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) F05D 2240/128 (20130101) F05D 2260/30 (20130101) F05D 2260/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815819 | Surace et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Raymond Surace (Newington, Connecticut); Eric A. Hudson (Harwinton, Connecticut) |
| ABSTRACT | A variable area turbine arrangement according to an exemplary aspect of the present disclosure includes, among other things, a variable vane assembly and a secondary flow system associated with the variable vane assembly. Flow modulation of a cooling fluid through the secondary flow system is changed simultaneously with actuation of the variable vane assembly. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/161593 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 11/24 (20130101) F01D 17/16 (20130101) F01D 17/162 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815821 | Sener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Alexander Martin Sener (Cincinnati, Ohio); Frederick Martin Heise (Cincinnati, Ohio); Monty Lee Shelton (Loveland, Ohio) |
| ABSTRACT | A stage of guide vanes for a machine includes a first variable vane assembly including an airfoil. The airfoil of the first variable vane assembly includes a first member and a second member each extending generally along a radial direction and the second member being moveable relative to the first member. The stage of guide vanes also includes a second variable vane assembly including an airfoil, the airfoil of the second variable vane assembly including a first member and a second member each extending generally along the radial direction and the second member being moveable relative to the first member, the second members of the airfoils of the first and second variable vane assemblies being moveable towards one another. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/118556 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) F01D 17/165 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815827 | Swift et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Anthony B. Swift (Waterboro, Maine); Ken F. Blaney (Middleton, New Hampshire); Paul M. Lutjen (Kennebunkport, Maine); Neil L. Tatman (Brentwood, New Hampshire); Dominic J. Mongillo (West Hartford, Connecticut) |
| ABSTRACT | A gas turbine engine component has a body extending between two circumferential sides, and between a leading edge and a trailing edge. A refractory metal core within the body forms at least one cooling circuit to utilize fluid to cool the body. When the refractory metal core is removed from the body, the at least one cooling circuit includes an inlet, an outlet, and a passage that varies in cross-sectional area between the inlet and outlet. A method of manufacturing a gas turbine engine, a method of manufacturing a core, and a refractory metal core are also disclosed. |
| FILED | Monday, January 25, 2016 |
| APPL NO | 15/005061 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Foundry Moulding B22C 9/103 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) F01D 5/187 (20130101) F01D 9/041 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/10 (20130101) F05D 2230/30 (20130101) F05D 2230/211 (20130101) F05D 2240/11 (20130101) F05D 2250/323 (20130101) F05D 2250/324 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815830 | McCaffrey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Michael G McCaffrey (Windsor, Connecticut); Scott D Virkler (Ellington, Connecticut); Tuan David Vo (Middletown, Connecticut) |
| ABSTRACT | The present disclosure provides an assembly for a gas turbine engine. The assembly may comprise a tierod, a bearing mounting ring, and a joint coupling the tierod to the bearing mounting ring. The joint may be configured to increase a volume of a bearing compartment on an inner surface of the bearing mounting ring. A coefficient of thermal expansion of the bearing mounting ring may be substantially the same as the coefficient of thermal expansion of the tierod. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/850379 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 25/005 (20130101) F01D 25/28 (20130101) F01D 25/162 (20130101) Original (OR) Class F01D 25/243 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/237 (20130101) F05D 2300/177 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815904 | Cafaro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Stefan Joseph Cafaro (Maineville, Ohio); James Ryan Reepmeyer (Cincinnati, Ohio); Gagan Adibhatla (Cincinnati, Ohio) |
| ABSTRACT | The subject matter of the present disclosure is directed to a turbine engine having an adaptive prognostic health management control system that passively monitors stall margin reductions and applies corrective trims to a power management schedule of the engine to recover operability over time whilst maintaining a sufficient level of stall margin over the life cycle of the engine. The control system can adjust the power management schedule as needed to sustain a target stall margin, which allows for a more optimized and gradual performance to operability trade-off. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294324 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/02 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/80 (20130101) F05D 2270/42 (20130101) F05D 2270/101 (20130101) F05D 2270/301 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815932 | Slaney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Brandon T. Slaney (West Hartford, Connecticut); Andrew S. Miller (Marlborough, Connecticut) |
| ABSTRACT | A convergent flap roller assembly is provided that includes a first hanger flange, a second hanger flange, a roller, and a pivot axle. Each hanger flange has a panel, a roller shaft, and at least one track tab. Each roller shaft extends outwardly from the respective panel, and includes a roller shaft bore. The roller has a center bore and an exterior contact surface. The roller shafts are received within the roller center bore and are in contact with each other, and the pivot axle extends through the roller shaft bores. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978939 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) F01D 17/14 (20130101) Jet-propulsion Plants F02K 1/1223 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/128 (20130101) F05D 2250/323 (20130101) F05D 2250/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816014 | Nasir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Shakeel Nasir (Torrance, California); John Schugardt (Chandler, Arizona); Mahmoud Mansour (Phoenix, Arizona); Richard Bonvouloir (Phoenix, Arizona) |
| ABSTRACT | A turbine engine incorporating a fine particle separation means. The turbine engine includes: a compressor, a diffuser, and a flow path positioned downstream from the diffuser, wherein the flow path comprises an outer annular wall and an inner annular wall between which the compressed air flows, and wherein the flow path comprises an arc that redirects the compressed air from flowing in a substantially radial flow direction to a substantially axial flow direction. The turbine engine further includes an extraction slot in the outer annular wall that fluidly connects with a scavenge plenum, the extraction slot also being positioned downstream axially along the flow path from the arc. The turbine engine further includes an aspiration slot, downstream from the extraction slot, that allows air from the plenum to recirculate back into the flow path. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/044704 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Separation B01D 45/04 (20130101) B01D 45/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 1/14 (20130101) F01D 25/32 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) F02C 7/052 (20130101) Non-positive-displacement Pumps F04D 29/444 (20130101) F04D 29/701 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2260/63 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816201 | Drake |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Drake (West Hartford, Connecticut) |
| ABSTRACT | A liner panel for a combustor of a gas turbine engine includes a rail which at least partially defines an impingement cavity. The rail includes a notch which faces toward the impingement cavity. A method of cooling a wall assembly within a combustor for of a gas turbine engine includes directing air through a support shell and a liner panel to form a pressure drop across the support shell that is less than about 80% of a pressure drop across the combustor and to also form a pressure drop across the liner panel greater than about 20% of the pressure drop across the combustor. |
| FILED | Friday, July 11, 2014 |
| APPL NO | 14/913165 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) F02C 7/24 (20130101) F02C 7/28 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/005 (20130101) F23R 3/06 (20130101) Original (OR) Class F23R 3/50 (20130101) F23R 3/60 (20130101) F23R 2900/00012 (20130101) F23R 2900/00017 (20130101) F23R 2900/03041 (20130101) F23R 2900/03042 (20130101) F23R 2900/03044 (20130101) F23R 2900/03045 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816369 | Pedrazzani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia) |
| ASSIGNEE(S) | Luna Innovations Incorporated (Roanoke, Virginia) |
| INVENTOR(S) | Janet Renee Pedrazzani (Newton, New Jersey); Matthew Davis (Roanoke, Virginia); Evan M. Lally (Blacksburg, Virginia) |
| ABSTRACT | A high-speed interrogation system is provided for interferometric sensors, one example of which is an EFPI sensor, that operates based on spectral interference. The system uses a two mode operation that includes a lower speed, accurate absolute measurement mode and a higher speed, relative measurement mode. The system achieves greater overall measurement accuracy and speed than known sensor interrogation approaches. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/185127 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35306 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816530 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jude Aaron Kelley (Bolton, Massachusetts); Richard Paul Kingsborough (Groton, Massachusetts); Roderick Russell Kunz (Acton, Massachusetts) |
| ABSTRACT | Methods and reagents are disclosed for improved detection of inorganic oxidizers, such as but not limited to chlorates, perchlorates, permanganates, dichromates, and osmium tetraoxides. In one aspect of the invention, latent acid-generating reagents are employed that are chemically stable at room temperature but undergo an acidic transformation when exposed to an elevated temperature or radiation. The latent reagent can be activated by heat or radiation (e.g., UV radiation). The resulting acidic reagent can then transfer a proton to the anion (i.e., chlorate, perchlorate, etc.) of the target analyte, forming an acid (i.e., chloric acid, perchloric acid) that is more easily vaporized and, hence, more easily detected. In another aspect of the invention, heat-sensitive inorganic salts and/or photosensitive onium salts are disclosed as reagents to carry out this method. In various embodiments, these reagents can be embedded in a swipe or other substrate, infused onto the swipe or sample via nebulizer, or otherwise deployed in a desorption chamber of an ion mobility spectrometer or similar detector. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687010 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 27/622 (20130101) G01N 33/227 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/19 (20150115) Y10T 436/24 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816649 | Keyser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Christian Keyser (Shalimar, Florida); Richard Kenneth Martin (Springboro, Ohio) |
| ABSTRACT | In a polarimeter, a polarization modulator changes a polarization phase of an output optical pulse with a modulation function that varies in time over the duration of the optical pulse. A static polarization state analyzer, which includes a one or more static polarization component analyzers and detectors, receives the modulated optical pulse after interaction with a target medium and provides time varying intensities of the polarization components of the received pulse. A signal processing module determines a polarization property of the target medium, such as a Mueller matrix, dependent upon time varied intensities over the duration of the received optical pulse. A time-division optical multiplexer may be used to combine the outputs from multiple static polarization component analyzers to form a single time-multiplexed signal comprising a plurality of optical pulses that are separated in time and passed to a single photo-detector. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878535 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/499 (20130101) Original (OR) Class G01S 7/4802 (20130101) G01S 17/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816724 | Coolbaugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Douglas Coolbaugh (Albany, New York); Gerald L. Leake, Jr. (Albany, New York) |
| ABSTRACT | There is set forth herein a method including depositing a layer formed of barrier material over a conductive material formation of a photonics structure; and removing material of the layer in a light signal transmitting region of the photonics structure. In one embodiment the barrier material can include silicon carbon nitride. In one embodiment the barrier material can include silicon nitride. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372763 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/136 (20130101) G02B 2006/12061 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) H01L 21/4857 (20130101) H01L 21/76202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816815 | Aieta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Francesco Aieta (Sunnyvale, California); Mikhail Kats (Madison, Wisconsin); Patrice Genevet (Valbonne, France); Federico Capasso (Cambridge, Massachusetts); Mohammadreza Khorasaninejad (Belmont, Massachusetts) |
| ABSTRACT | Multi-wavelength light is directed to an optic including a substrate and achromatic metasurface optical components deposited on a surface of the substrate. The achromatic metasurface optical components comprise a pattern of dielectric resonators. The dielectric resonators have distances between adjacent dielectric resonators; and each dielectric resonator has a width, w, that is distinct from the width of other dielectric resonators. A plurality of wavelengths of interest selected from the wavelengths of the multi-wavelength light are deflected with the achromatic metasurface optical components at a shared angle or to or from a focal point at a shared focal length. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 15/534642 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) G02B 5/203 (20130101) G02B 5/1809 (20130101) G02B 27/4211 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817291 | Corbal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jesus Corbal (King City, Oregon); Rohan Sharma (Hillsboro, Oregon); Simon Steely, Jr. (Hudson, New Hampshire); Chinmay Ashok (Beaverton, Oregon); Kent D. Glossop (Nashua, New Hampshire); Dennis Bradford (Portland, Oregon); Paul Caprioli (Forest Grove, Oregon); Louise Huot (Hillsboro, Oregon); Kermin ChoFleming (Hudson, Massachusetts); Barry Tannenbaum (Nashua, New Hampshire) |
| ABSTRACT | Systems, methods, and apparatuses relating to swizzle operations and disable operations in a configurable spatial accelerator (CSA) are described. Certain embodiments herein provide for an encoding system for a specific set of swizzle primitives across a plurality of packed data elements in a CSA. In one embodiment, a CSA includes a plurality of processing elements, a circuit switched interconnect network between the plurality of processing elements, and a configuration register within each processing element to store a configuration value having a first portion that, when set to a first value that indicates a first mode, causes the processing element to pass an input value to operation circuitry of the processing element without modifying the input value, and, when set to a second value that indicates a second mode, causes the processing element to perform a swizzle operation on the input value to form a swizzled input value before sending the swizzled input value to the operation circuitry of the processing element, and a second portion that causes the processing element to perform an operation indicated by the second portion the configuration value on the input value in the first mode and the swizzled input value in the second mode with the operation circuitry. |
| FILED | Saturday, March 30, 2019 |
| APPL NO | 16/370915 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30036 (20130101) Original (OR) Class G06F 9/30145 (20130101) G06F 15/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817737 | Kaur |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America, as represented by the Secretary of the Army (Fort Belvoir, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Balvinder Kaur (Centreville, Virginia) |
| ABSTRACT | A sensor system is disclosed, which includes a sensor configured to measure electromagnetic energy levels received from skin of a human subject not in contact with the sensor; a data processing unit configured to determine multiple heart rate metrics of the human subject from the electromagnetic energy levels measured by the sensor; and an output device. The output device is configured to indicate a physiological characteristic of the human subject determined from the multiple heart rate metrics of the human subject determined by the data processing unit. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/264728 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/117 (20130101) A61B 5/165 (20130101) A61B 5/0205 (20130101) A61B 5/02125 (20130101) A61B 5/02405 (20130101) A61B 5/02427 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/40 (20130101) G06K 9/42 (20130101) G06K 9/00885 (20130101) Original (OR) Class G06K 2009/00939 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817794 | Chattopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ishanu Chattopadhyay (Chicago, Illinois); Hod Lipson (Ithaca, New York) |
| ABSTRACT | Methods, systems, and devices are disclosed for determining causality among data. In one aspect, a method includes receiving a first data and a second data associated with a first event and a second event, respectively; and determining a data set including quantitative causality dependence values between the first and the second data. |
| FILED | Thursday, June 02, 2016 |
| APPL NO | 15/172147 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Computer Systems Based on Specific Computational Models G06N 5/048 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817797 | Govia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corp (Cambridge, Massachusetts) |
| INVENTOR(S) | Luke Colin Gene Govia (Cambridge, Massachusetts); Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | A method for characterizing an N-qubit process, for N an integer greater than 1. In some embodiments, the method includes performing a plurality of characterization measurements of the N-qubit process to form a plurality of process maps, and fitting the plurality of process maps with a composition of K-qubit processes, K being an integer greater than 1 and less than N. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 16/679126 |
| ART UNIT | 2849 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3877 (20130101) G06F 2009/3883 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818016 | Piekniewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRAIN CORPORATION (San Diego, California) |
| ASSIGNEE(S) | Brain Corporation (San Diego, California) |
| INVENTOR(S) | Filip Piekniewski (San Diego, California); Micah Richert (San Diego, California); Dimitry Fisher (San Diego, California); Patryk Laurent (San Diego, California); Csaba Petre (San Diego, California) |
| ABSTRACT | Systems and methods for predictive/reconstructive visual object tracking are disclosed. The visual object tracking has advanced abilities to track objects in scenes, which can have a variety of applications as discussed in this disclosure. In some exemplary implementations, a visual system can comprise a plurality of associative memory units, wherein each associative memory unit has a plurality of layers. The associative memory units can be communicatively coupled to each other in a hierarchical structure, wherein data in associative memory units in higher levels of the hierarchical structure are more abstract than lower associative memory units. The associative memory units can communicate to one another supplying contextual data. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357536 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 12/08 (20130101) G06F 2212/401 (20130101) G06F 2212/1016 (20130101) Image Data Processing or Generation, in General G06T 1/60 (20130101) G06T 7/0002 (20130101) G06T 7/20 (20130101) Original (OR) Class G06T 9/00 (20130101) G06T 9/002 (20130101) G06T 9/004 (20130101) G06T 2207/20084 (20130101) Pictorial Communication, e.g Television H04N 19/503 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818023 | Gupta |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mohit Gupta (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods and media for encoding structured light imaging patterns and estimating depths in a scene are provided. In some embodiments, a system for estimating depths in a scene is provided, the system comprising: a light source; an image sensor; a hardware processor programmed to: cause the light source to emit K light patterns toward the scene, each of the K light patterns is different and includes a trapezoid-shaped wave, and at least one of the K light patterns includes at least two trapezoid-shaped waves; cause the image sensor to generate an intensity value during emission of each of the K light patterns such that the pixel is associated with at least K intensity values; determine a depth estimate for a portion of the scene imaged by the pixel based on the K intensity values associated with the pixel. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/112474 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/521 (20170101) Original (OR) Class G06T 2207/10152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818193 | Sullivan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Kevin Sullivan (Burlington, Massachusetts); Matthew Roberts (North Chelmsford, Massachusetts); Michael Knapp (Orlando, Florida); Brian Riordan (Pennington, New Jersey) |
| ABSTRACT | A communications training system is provided having a user interface, a computer-based simulator and a performance measurement database. The user interface is configured to receive a speech communication input from the user based on a training content and the computer-based simulator is configured to transform the speech communication to a text data whereby the text data can be aligned to performance measurement database values to determine a performance measure of the speech communication. The format of the text data and the performance measurement database values enable the speech communication to be aligned with predefined performance measurement database values representing expected speech communications for that training content. |
| FILED | Monday, February 20, 2017 |
| APPL NO | 15/437399 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 5/04 (20130101) G09B 5/062 (20130101) Original (OR) Class G09B 9/003 (20130101) G09B 19/04 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/26 (20130101) G10L 15/187 (20130101) G10L 15/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819028 | Rivera |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | David F Rivera (Westerly, Rhode Island) |
| ABSTRACT | A tunable antenna includes a base supporting a support and hollow tube opposing and spaced apart from one another, and spaced-apart and parallel plates. Each plate is coupled only at one end thereof to one of the support and hollow tube. One of the plates located furthest from the base extends past the hollow tube and is spaced apart therefrom. A shaft extends through the hollow tube and the one plate extending past the hollow tube. A tuning plate is coupled to the end of the shaft. A tuning piston is coupled to the shaft and is adapted for movement within the hollow tube where such movement changes the resonant frequency of the antenna. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 16/523213 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/01 (20130101) Original (OR) Class H01Q 9/0414 (20130101) H01Q 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819082 | Josset et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Damien Josset (Covington, Louisiana); Anna Yue (Auburn, Georgia); Weilin Hou (Slidell, Louisiana) |
| ABSTRACT | Systems and methods are provided for optimizing the energy output of a laser system, such as a Light Detection and Ranging (LIDAR) system, by allowing the laser system to be tuned while the laser is in operation. For example, in an embodiment, a sensor, such as a photoresistor, is used to perform a scan to determine whether turning the crystal will result in increased energy. Crystal turners, such as servo motors, can be used to turn the crystal until the energy stops increasing. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 16/523088 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0092 (20130101) H01S 3/094 (20130101) H01S 3/131 (20130101) Original (OR) Class H01S 3/0602 (20130101) H01S 3/1083 (20130101) H01S 3/1312 (20130101) H01S 3/08086 (20130101) H01S 3/094096 (20130101) H01S 5/0092 (20130101) H01S 5/0604 (20130101) H01S 5/1092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819437 | Johnson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEADOWAVE, LLC (Washington, District of Columbia) |
| ASSIGNEE(S) | MEADOWAVE, LLC (Washington, District of Columbia) |
| INVENTOR(S) | Lee James Johnson (Washington, District of Columbia) |
| ABSTRACT | A self-organizing network of nodes communicates with uncollimated optical pulses. The nodes use low-power, unmoving, broad-beam optical interfaces, low-power processors, and communication algorithms based on timeslots within a timeframe. Nodes self-organize to form the network by pulsing detectors and sources to find neighboring nodes, confirm connections, transmit and store data, and exchange partner node identities. Two- or three-dimensional networks can thereby self-organize without external awareness of network topology, and can repair themselves when nodes move or fail. Node communication may be synchronous, thereby allowing for images of the environment status, and activation of the environment is possible via node stimulators. After forming a network, a cluster of nodes may be read out to provide data from node sensors. Implementation of selected features in the nodes' processors enable formation of networks that are unidirectional, bidirectional, serial, or complex including the formation of meshed networks with adjustable link weights capable of computation. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293280 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/27 (20130101) Original (OR) Class H04B 10/806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819726 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Yingbo Song (Hazlet, New Jersey); Angelos D. Keromytis (New York, New York); Salvatore J. Stolfo (New York, New York) |
| ABSTRACT | Systems, methods, and media for detecting network anomalies are provided. In some embodiments, a training dataset of communication protocol messages having argument strings is received. The content and structure associated with each of the argument strings is determined and a probabilistic model is trained using the determined content and structure of each of the argument strings. A communication protocol message having an argument string that is transmitted from a first processor to a second processor across a computer network is received. The received communication protocol message is compared to the probabilistic model and then it is determined whether the communication protocol message is anomalous. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/046528 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1466 (20130101) H04L 67/02 (20130101) H04L 69/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819752 | Skowyra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Richard W. Skowyra (Somerville, Massachusetts); Steven R. Gomez (Cambridge, Massachusetts) |
| ABSTRACT | A computer-implemented method for quantitatively assessing a defense technique. The method includes executing a reasoning engine that receives as an input to the reasoning engine a query that includes an indicia of a defense technique to a computer security threat. The method further includes translating the defense technique into a propositional logic constraint on a queryable representation of a Boolean formula representing a model complied from a set of computer security threats and a set of defense techniques. The method also includes performing an assessment of the defense technique based on the propositional logic constraint on the queryable representation, to quantify the defense technique relative to a member of the set of computer security threats. The method further includes displaying a result of the assessment to indicate a level of security provided by the defense technique to the member. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829827 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/903 (20190101) G06F 16/9027 (20190101) G06F 17/11 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/105 (20130101) H04L 63/205 (20130101) Original (OR) Class H04L 63/1433 (20130101) H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820057 | Eberle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Hans Eberle (Mountain View, California); Larry Robert Dennison (Mendon, Massachusetts) |
| ABSTRACT | A communication method between a source device and a target device utilizes speculative connection setup between the source device and the target device, target-device-side packet ordering, and fine-grained ordering to remove packet dependencies. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376988 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/20 (20130101) H04L 45/7453 (20130101) H04L 47/283 (20130101) H04L 47/624 (20130101) Pictorial Communication, e.g Television H04N 21/2387 (20130101) H04N 21/4302 (20130101) H04N 21/6583 (20130101) H04N 21/23406 (20130101) H04N 21/47217 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820404 | Cross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Niskayuna, New York) |
| INVENTOR(S) | Andrew Thomas Cross (Waterford, New York); Alexander Kagan (Guilderland, New York); Thomas Raber (East Berne, New York); Vasile Bogdan Neculaes (Niskayuna, New York); Nidhishri Tapadia (Glenville, New York); Ashraf Atalla (Portland, Oregon); Pierre Fernand Habig (Rambouillet, France); Frederic Dahan (Le Chesnay, France) |
| ABSTRACT | A portable neutron generator is provided that does not utilize liquid cooling. The portable neutron generator includes a vacuum chamber housing defining a vacuum chamber and an ion beam inlet. The portable neutron generator also includes a rotating target positioned within the vacuum chamber. The ion beam inlet is oriented to receive ions such that the ions impinge upon the rotating target to cause neutrons to be emitted. The rotating target comprises a copper alloy. The portable neutron generator also includes a motor core positioned within the vacuum chamber and coupled to the rotating target. A motor stator is electromagnetically coupled with the motor core. The motor core is configured to rotate the rotating target at greater than 200 Hz during operation. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106688 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 4/02 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/04 (20130101) H05H 3/06 (20130101) H05H 6/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10813552 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Kunal Ghosh (Mountain View, California); Laurie D. Burns (Menlo Park, California); Abbas El Gamal (Palo Alto, California); Mark J. Schnitzer (Palo Alto, California); Eric Cocker (Palo Alto, California); Tatt Wei Ho (Stanford, California) |
| ABSTRACT | Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/444049 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/0071 (20130101) Original (OR) Class A61B 5/0082 (20130101) A61B 5/489 (20130101) A61B 90/20 (20160201) A61B 2090/306 (20160201) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2562/04 (20130101) A61B 2562/0233 (20130101) A61B 2576/026 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) G02B 21/0008 (20130101) G02B 21/008 (20130101) G02B 21/16 (20130101) G02B 21/36 (20130101) G02B 21/361 (20130101) G02B 21/362 (20130101) G02B 21/365 (20130101) G02B 27/141 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/30016 (20130101) G06T 2207/30101 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) H04N 5/2256 (20130101) H04N 5/23296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814406 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Zhigang Wang (South Windsor, Connecticut); Changsheng Guo (South Windsor, Connecticut); Robert W. Day (Enfield, Connecticut); Gordon Miller Reed (Plantsville, Connecticut) |
| ABSTRACT | A cutting tool comprising a tool body comprising a shank and a cutter opposite the shank, the body defining a length from a shank end to an end face opposite the shank end, a central axis extends along the length of the body; at least one tooth having a cutting edge, the cutting edge extending along the tooth from the shank to the end face; a flute formed adjacent the at least one tooth; at least one cooling channel formed in the tooth proximate the at least one cutting edge, the at least one cooling channel having an elongated cross sectional shape with an elliptical portion and a circular portion opposite the elliptical portion, wherein the elliptical portion is located proximate the cutting edge. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/392999 |
| ART UNIT | 3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Turning; Boring B23B 51/06 (20130101) Original (OR) Class B23B 2250/125 (20130101) B23B 2251/40 (20130101) Milling B23C 5/28 (20130101) B23C 2250/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 408/45 (20150115) Y10T 408/455 (20150115) Y10T 409/304032 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814490 | Malekos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno (Reno, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno (Reno, Nevada) |
| INVENTOR(S) | Steven Malekos (Reno, Nevada); Grant Korgan (Reno, Nevada); Jesse D. Adams (Reno, Nevada) |
| ABSTRACT | In one embodiment, the present disclosure provides a target or mold having one or more support arms coupled to a substrate. The support arm can be used in handling or positioning a target. In another embodiment, the present disclosure provides target molds, targets produced using such molds, and a method for producing the targets and molds. In various implementations, the targets are formed in a number of disclosed shapes, including a funnel cone, a funnel cone having an extended neck, those having Gaussian-profile, a cup, a target having embedded metal slugs, metal dotted foils, wedges, metal stacks, a Winston collector having a hemispherical apex, and a Winston collector having an apex aperture. In yet another embodiment, the present disclosure provides a target mounting and alignment system. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870470 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 11/00 (20130101) Original (OR) Class Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/022 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 40/16 (20130101) X-ray Technique H05G 2/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 6/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/26 (20150115) Y10T 428/265 (20150115) Y10T 428/31678 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814724 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Taek Soon Lee (Berkeley, California); Aram Kang (Richmond, California) |
| ABSTRACT | The present invention provides for a genetically modified host cell capable of producing isopentenol and/or 3-methyl-3-butenol, comprising (a) an increased expression of phosphomevalonate decarboxylase (PMD) (b) an increased expression of a phosphatase capable of converting isopentenol into 3-methyl-3-butenol, (c) optionally the genetically modified host cell does not express, or has a decreased expression of one or more of NudB, phosphomevalonate kinase (PMK), and/or PMD, and (d) optionally one or more further enzymes capable of converting isopentenol and/or 3-methyl-3-butenol into a third compound, such as isoprene. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388556 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) Original (OR) Class B60K 2370/173 (20190501) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 69/006 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) C07F 9/098 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 136/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/16 (20130101) C12N 9/88 (20130101) C12N 9/1025 (20130101) C12N 9/1205 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) C12P 7/04 (20130101) Enzymes C12Y 101/01088 (20130101) C12Y 203/0301 (20130101) C12Y 207/01036 (20130101) C12Y 401/01033 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 2013/9314 (20130101) G01S 2013/9317 (20130101) G01S 2013/9323 (20200101) G01S 2013/9324 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815125 | Gopalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Padma Gopalan (Madison, Wisconsin); Michael Scott Arnold (Middleton, Wisconsin); Catherine Kanimozhi Kansiusarulsamy (Madison, Wisconsin); Matthew John Shea (Madison, Wisconsin) |
| ABSTRACT | Polymers having pendant polycyclic aromatic hydrocarbon (PAH) groups covalently bound to the polymer backbone via thioester bonds are provided. The PAH groups are covalently bound to the backbone of the polymer by a molecular linker that includes a thioester bond. Also provided are dispersions of polymer-coated carbon nanotubes and carbon nanotube films formed from the dispersions. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863087 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) B05D 3/107 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Original (OR) Class C01B 2202/02 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 293/005 (20130101) C08F 2438/03 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/008 (20130101) C09D 5/20 (20130101) C09D 7/65 (20180101) C09D 153/005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/746 (20130101) Y10S 977/845 (20130101) Y10S 977/847 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815277 | Rabadan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute for Advanced Study (Princeton, New Jersey) |
| ASSIGNEE(S) | INSTITUTE FOR ADVANCED STUDY (Princeton, New Jersey) |
| INVENTOR(S) | Raul Rabadan (New York, New York); Michael Krasnitz (Princeton, New Jersey); Harlan Robins (Seattle, Washington); Daniela Witten (Princeton, New Jersey); Arnold Levine (Doylestown, Pennsylvania) |
| ABSTRACT | The invention relates to inhibitory nucleotide signal sequences or “INS” sequences in the genomes of lentiviruses. In particular the invention relates to the AGG motif present in all viral genomes. The AGG motif may have an inhibitory effect on a virus, for example by reducing the levels of, or maintaining low steady-state levels of, viral RNAs in host cells, and inducing and/or maintaining in viral latency. In one aspect, the invention provides vaccines that contain, or are produced from, viral nucleic acids in which the AGG sequences have been mutated. In another aspect, the invention provides methods and compositions for affecting the function of the AGG motif, and methods for identifying other INS sequences in viral genomes. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/228451 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/53 (20130101) A61K 2039/525 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15021 (20130101) C12N 2740/15034 (20130101) C12N 2740/16021 (20130101) C12N 2740/16043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815468 | Spodsberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark); Tarana Shaghasi (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains. |
| FILED | Wednesday, October 31, 2018 |
| APPL NO | 16/176553 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815856 | Masoudi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mansour Masoudi (Mill Creek, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mansour Masoudi (Mill Creek, Washington) |
| ABSTRACT | Disclosed is a honeycomb catalyst substrate core having geometrically non-linear flow channels. In an embodiment, the honeycomb catalyst substrate core includes helical flow channels. In another embodiment, the honeycomb catalyst substrate core includes sinusoidal flow channels. In yet another embodiment, the honeycomb catalyst substrate core includes helical plus sinusoidal flow channels. The honeycomb catalyst substrate core comprises a plurality of parallel non-linear flow channels formed along a longitudinal axis of symmetry of the catalyst substrate core, each non-linear flow channel configured such that eddies occurs during engine exhaust gas flow. Also disclosed is a method for manufacturing a ceramic honeycomb having non-linear flow channels, comprising the steps extrusion soft ceramic material through a die whilst the die moves through six degrees of freedom along its axis of symmetry. Disclosure includes a method for manufacturing a ceramic honeycomb having non-linear flow channels using three-dimensional printing. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 15/677019 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/04 (20130101) B01J 37/08 (20130101) B01J 37/0009 (20130101) B01J 37/0215 (20130101) B01J 37/0217 (20130101) B01J 37/0225 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/00 (20130101) C04B 38/0006 (20130101) C04B 38/0006 (20130101) C04B 38/0077 (20130101) C04B 38/0096 (20130101) C04B 2111/0081 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/281 (20130101) F01N 3/2828 (20130101) F01N 3/2842 (20130101) Original (OR) Class F01N 2330/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816179 | Nimma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | SIGNIFY HOLDING B.V. (Eindhoven, Netherlands) |
| INVENTOR(S) | Sridhar Reddy Nimma (Cumming, Georgia); Matthew A. Davis (Orange, California) |
| ABSTRACT | A lighting fixture can comprise a substantially flat sheet of metal supporting a circuit that comprises one or more light emitting diodes with one or more associated optics for manipulating emitted light. The circuit can be attached to, mounted next to, or integrated with the sheet of metal. In some examples, a layer of dielectric material adheres to the sheet of metal, and circuit elements adhere to the layer of dielectric material. Such circuit elements may comprise electrical traces, light emitting diodes, and/or a light emitting diode driver. The sheet of metal can provide a substrate for the circuit or a support for a freestanding circuit board that may be rigid or flexible. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436421 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 8/086 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/007 (20130101) F21V 19/003 (20130101) F21V 21/116 (20130101) F21V 23/005 (20130101) Original (OR) Class F21V 23/008 (20130101) F21V 23/0464 (20130101) F21V 23/0471 (20130101) F21V 31/005 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2131/103 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2105/10 (20160801) F21Y 2115/10 (20160801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816462 | DiBenedetto |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mission Support and Test Services, LLC (Las Vegas, Nevada) |
| ASSIGNEE(S) | Mission Support and Test Services, LLC (Las Vegas, Nevada) |
| INVENTOR(S) | John DiBenedetto (Santa Barbara, California) |
| ABSTRACT | Gas containers configured to contain a type of gas to allow optical detection of the gas in a spectral region of detection defined by the type of gas. The system includes a gas container containing the gas, the gas container formed from a material substantially optically transparent in the spectral region of detection defined by the type of gas and optic imaging, and a frame for holding the gas container in a position for the optical detection. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/286446 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/12 (20130101) G01J 2005/0077 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3504 (20130101) Original (OR) Class G01N 33/0006 (20130101) G01N 33/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816485 | Jimenez, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Edward Steven Jimenez, Jr. (Albuquerque, New Mexico); Kyle R. Thompson (Albuquerque, New Mexico) |
| ABSTRACT | A method and apparatus for identifying a material in an object. An image of the object generated from energy passing through the object is obtained by a computer system. The computer system estimates attenuations for pixels in a sensor system from the image of the object to form estimated attenuations. The estimated attenuations represent a loss of the energy that occurs from the energy passing through the object. The computer system also identifies the material in the object using the estimated attenuations and known attenuation information for identifying the material in the object. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362241 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/00 (20130101) G01V 5/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816556 | Vertes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Akos Vertes (Reston, Virginia); Bennett N. Walker (Washington, District of Columbia); Jessica A. Stolee (Washington, District of Columbia); Scott T. Retterer (Oak Ridge, Tennessee) |
| ABSTRACT | The production and use of semiconducting nanopost arrays made by nanofabrication is described herein. These nanopost arrays (NAPA) provide improved laser ionization yields and controllable fragmentation with switching or modulation capabilities for mass spectrometric detection and identification of samples deposited on them. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/813490 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) G01N 33/6848 (20130101) G01N 33/6851 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/0418 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816587 | Warburton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XIA LLC (Hayward, California) |
| ASSIGNEE(S) | XIA LLC (Hayward, California) |
| INVENTOR(S) | William K. Warburton (Oakland, California); Jackson T. Harris (Berkeley, California) |
| ABSTRACT | A technique for characterizing the noise behavior of a superconducting tunnel junction (STJ) detector as a function of its applied bias voltage Vb by stepping the STJ's bias voltage across a predetermined range and, at each applied bias, making multiple measurements of the detector's current, calculating their mean and their standard deviation from their mean, and using this standard deviation as a measure of the STJ detector's noise at that applied bias. Because the method is readily executed under computer control, it is particularly useful when large numbers of STJ detectors require biasing, as in STJ detector arrays In a preferred implementation, the STJ is measured under computer control by attaching it to a digital spectrometer comprising a digital x-ray processor (DXP) coupled to a preamplifier that can set the STJ's bias voltage Vb using a digital-to-analog converter (DAC) controlled by the DXP. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/141681 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816942 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Soumyadip Ghosh (PeekSkill, New York); Jonathan R. Hosking (Scarsdale, New York); Ramesh Natarajan (Pleasantville, New York); Shivaram Subramanian (Danbury, Connecticut); Xiaoxuan Zhang (Park Ridge, New Jersey) |
| ABSTRACT | A predictive-control approach allows an electricity provider to monitor and proactively manage peak and off-peak residential intra-day electricity usage in an emerging smart energy grid using time-dependent dynamic pricing incentives. The daily load is modeled as time-shifted, but cost-differentiated and substitutable, copies of the continuously-consumed electricity resource, and a consumer-choice prediction model is constructed to forecast the corresponding intra-day shares of total daily load according to this model. This is embedded within an optimization framework for managing the daily electricity usage. A series of transformations are employed, including the reformulation-linearization technique (RLT) to obtain a Mixed-Integer Programming (MIP) model representation of the resulting nonlinear optimization problem. In addition, various regulatory and pricing constraints are incorporated in conjunction with the specified profit and capacity utilization objectives. |
| FILED | Tuesday, November 15, 2016 |
| APPL NO | 15/352054 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) Original (OR) Class G05B 2219/40458 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0206 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/003 (20200101) H02J 3/381 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 20/222 (20130101) Y04S 50/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817289 | Hari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Siva Hari (Santa Clara, California); Michael Sullivan (San Jose, California); Timothy Tsai (Santa Clara, California); Stephen W. Keckler (Austin, Texas); Abdulrahman Mahmoud (Savoy, Illinois) |
| ABSTRACT | Software-only and software-hardware optimizations to reduce the overhead of intra-thread instruction duplication on a GPU or other instruction processor are disclosed. The optimizations trade off error containment for performance and include ISA extensions with limited hardware changes and area costs. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/150410 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30029 (20130101) Original (OR) Class G06F 9/30032 (20130101) G06F 9/30101 (20130101) G06F 11/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818400 | Perkins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Lindsay John Perkins (Pleasanton, California) |
| ABSTRACT | A hybrid indirect-drive/direct drive for inertial confinement fusion utilizing laser beams from a first direction and laser beams from a second direction including a central fusion fuel component; a first portion of a shell surrounding said central fusion fuel component, said first portion of a shell having a first thickness; a second portion of a shell surrounding said fusion fuel component, said second portion of a shell having a second thickness that is greater than said thickness of said first portion of a shell; and a hohlraum containing at least a portion of said fusion fuel component and at least a portion of said first portion of a shell; wherein said hohlraum is in a position relative to said first laser beam and to receive said first laser beam and produce X-rays that are directed to said first portion of a shell and said fusion fuel component; and wherein said fusion fuel component and said second portion of a shell are in a position relative to said second laser beam such that said second portion of a shell and said fusion fuel component receive said second laser beam. |
| FILED | Thursday, January 18, 2018 |
| APPL NO | 15/874207 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fusion Reactors G21B 1/19 (20130101) Original (OR) Class G21B 1/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818403 | Kitto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Allyson Kitto (Corvallis, Oregon); Daniel Ingersoll (Oak Ridge, Tennessee); Jose N. Reyes, Jr. (Corvallis, Oregon) |
| ABSTRACT | A method of loading fuel in multiple reactor cores associated with a plurality of fuel cycles. The method includes, in a first fuel cycle, loading a first reactor core with a first fuel assembly selected from a first batch of fuel, loading the first reactor core with a first partially spent fuel assembly from a second batch of fuel, loading a second reactor core with a second fuel assembly from the first batch of fuel, and loading the second reactor core with a second partially spent fuel assembly from the second batch of fuel. In a second fuel cycle, which is performed after a completion of the first fuel cycle, the method includes loading the second reactor core with a fresh fuel assembly, and loading the second reactor core with the first fuel assembly from the first batch of fuel. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/445186 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 5/18 (20130101) G21C 19/07 (20130101) G21C 19/205 (20130101) Original (OR) Class Nuclear Power Plant G21D 1/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818416 | Selvamanickam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | The University of Houston System (Houston, Texas) |
| INVENTOR(S) | Venkat Selvamanickam (Houston, Texas) |
| ABSTRACT | A REBCO superconductor tape that can achieve a lift factor greater than or equal to approximately 3.0 or 4.0 in an approximately 3 T magnetic field applied perpendicular to a REBCO tape at approximately 30 K. In an embodiment, the REBCO superconductor tape can include a critical current density less than or equal to approximately 4.2 MA/cm2 at 77 K in the absence of an external magnetic field. In another embodiment, the REBCO superconductor tape can include a critical current density greater than or equal to approximately 12 MA/cm2 at approximately 30 K in a magnetic field of approximately 3 T having an orientation parallel to a c-axis. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/242587 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/08 (20130101) H01B 12/02 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/143 (20130101) H01L 39/2483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818514 | Christensen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Kyle B. Christensen (Los Alamos, New Mexico) |
| ABSTRACT | A system for manipulating a filament can include a filament supply from which a filament can be drawn, the filament supply being positioned along an axis, a vacuum manipulator assembly positioned along the axis, wherein the vacuum manipulator assembly is configured to engage the filament when a vacuum is drawn through the vacuum manipulator assembly and draw the filament along the axis to a workpiece, and a welding tool comprising a welding head positioned along the axis between the filament supply and the vacuum manipulator assembly, the welding tool being configured to weld the filament to the workpiece. |
| FILED | Wednesday, July 11, 2018 |
| APPL NO | 16/033068 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4825 (20130101) Original (OR) Class H01L 24/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818832 | Jie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Qing Jie (Houston, Texas); Zhifeng Ren (Houston, Texas); Gang Chen (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are methods for the manufacture of n-type and p-type filled skutterudite thermoelectric legs of an electrical contact. A first material of CoSi2 and a dopant are ball-milled to form a first powder which is thermo-mechanically processed with a second powder of n-type skutterudite to form a n-type skutterudite layer disposed between a first layer and a third layer of the doped-CoSi2. In addition, a plurality of components such as iron, and nickel, and at least one of cobalt or chromium are ball-milled form a first powder that is thermo-mechanically processed with a p-type skutterudite layer to form a p-type skutterudite layer “second layer” disposed between a first and a third layer of the first powder. The specific contact resistance between the first layer and the skutterudite layer for both the n-type and the p-type skutterudites subsequent to hot-pressing is less than about 10.0 μΩ·cm2. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627593 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/08 (20130101) H01L 35/14 (20130101) H01L 35/18 (20130101) H01L 35/20 (20130101) H01L 35/22 (20130101) H01L 35/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818849 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Donglin Zhao (Hyougo, Japan); Qinghe Wu (Chicago, Illinois); Luping Yu (Chicago, Illinois); Zhengxu Cai (Chicago, Illinois) |
| ABSTRACT | The present disclosure relates to α-substituted perylene diimide (PDI) derivatives as small molecular and polymerized electron acceptors in organic photovoltaic cells. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 16/067501 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 519/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/123 (20130101) C08G 61/126 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 3/14 (20130101) C09B 5/62 (20130101) C09B 57/001 (20130101) C09B 69/008 (20130101) C09B 69/102 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/142 (20130101) H01L 51/0032 (20130101) H01L 51/0036 (20130101) H01L 51/42 (20130101) H01L 51/0052 (20130101) H01L 51/0053 (20130101) H01L 51/0056 (20130101) H01L 51/0058 (20130101) H01L 51/0068 (20130101) H01L 51/0071 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0074 (20130101) H01L 51/0094 (20130101) H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818917 | Thesma Chandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Girija Thesma Chandran (Irvine, California); Reginald M. Penner (Newport Beach, California) |
| ABSTRACT | Systems and methods that facilitate enhancing the energy storage capabilities of MnO2 in nanowire energy storage devices such as nanowire-based capacitors or batteries. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934884 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/04 (20130101) C25D 1/006 (20130101) C25D 3/48 (20130101) C25D 5/10 (20130101) C25D 5/022 (20130101) C25D 7/0607 (20130101) C25D 9/02 (20130101) C25D 9/04 (20130101) C25D 9/08 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70058 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/46 (20130101) H01G 11/50 (20130101) H01G 11/56 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/60 (20130101) H01M 4/75 (20130101) H01M 4/139 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0404 (20130101) H01M 4/0452 (20130101) H01M 4/502 (20130101) H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 10/0525 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819270 | Martinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); William Paterson University of New Jersey (Wayne, New Jersey) |
| INVENTOR(S) | Alex B. Martinson (Naperville, Illinois); Nari Jeon (Skokie, Illinois); Stephen K. Gray (Wheaton, Illinois); Jonathan J. Foley, IV (Wayne, New Jersey) |
| ABSTRACT | Tailoring the emission spectra of a solar thermophotovoltaic emitter away from that of a blackbody, thereby minimizing transmission and thermalization loss in the energy receiver, is a viable approach to circumventing the Shockley-Queisser limit to single junction solar energy conversion. Embodiments allow for radically tuned selective thermal emission that leverages the interplay between two resonant phenomena in a simple planar structure—absorption in weakly-absorbing thin films and reflection in multi-layer dielectric stacks. A virtual screening approach is employed based on Pareto optimality to identify a small number of promising structures for a selective thermal emitter from a search space of millions, several of which approach the ideal values of a step-function selective thermal emitter. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923909 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4831 (20130101) G06F 9/45516 (20130101) G06F 11/3628 (20130101) G06F 16/2453 (20190101) G06F 30/00 (20200101) G06F 30/20 (20200101) G06F 30/337 (20200101) G06F 30/398 (20200101) G06F 2101/02 (20130101) G06F 2111/06 (20200101) G06F 2119/06 (20200101) G06F 2119/08 (20200101) G06F 2212/1041 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0207 (20130101) H01L 31/0547 (20141201) H01L 33/10 (20130101) H01L 33/46 (20130101) H01L 51/5265 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819721 | Jenkins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Chris Jenkins (Albuquerque, New Mexico) |
| ABSTRACT | Technologies relating to monitoring communications traffic to detect potential attacks on industrial control system networks and building automation system networks are described herein. In an embodiment, a monitoring device receives a plurality of communications from a control network. The monitoring device transmits the communications to a computing device. Based on the communications, the computing device generates a listing of devices that communicated by way of the control network over a period of time, and computes a volume of traffic between each pair of devices in the listing of devices. The computing device then outputs a graphical user interface (GUI) by way of display, the GUI comprising data indicative of the computed volumes of traffic, which may be indicative of a potential attack on the control network. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899893 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/22 (20130101) H04L 43/045 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819725 | Abbaszadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, None) |
| INVENTOR(S) | Masoud Abbaszadeh (Clifton Park, New York); Lalit Keshav Mestha (North Colonie, New York) |
| ABSTRACT | In some embodiments, a plurality of monitoring nodes each generate a series of current monitoring node values over time that represent a current operation of the industrial asset. An attack detection computer platform may receive the series of current monitoring node values and generate a set of current feature vectors including a current feature for capturing transients (e.g., local transients and/or global transients). The attack detection computer platform may also access an attack detection model having at least one decision boundary that was created using at least one of a set of normal feature vectors and/or a set of attacked feature vectors. The attack detection model may then be executed such that an attack alert signal is transmitted by the attack detection computer platform, when appropriate, based on the set of current feature vectors (including the current feature to capture transients) and the at least one decision boundary. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964644 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/55 (20130101) G06F 21/552 (20130101) G06F 21/554 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10813324 | Koch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Karen Elaine Koch (Gainesville, Florida); Sylvia Morais De Sousa (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Karen Elaine Koch (Gainesville, Florida); Sylvia Morais De Sousa (Gainesville, Florida) |
| ABSTRACT | The subject invention concerns materials and methods for modulating seed size in plants. In one embodiment, seed size is decreased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed size is increased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. The subject invention also concerns materials and methods for modulating seed number or sugar content in plants. In one embodiment, seed number or sugar content is increased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed number or sugar content is decreased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. |
| FILED | Monday, May 19, 2008 |
| APPL NO | 12/599652 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/00 (20130101) A01H 5/10 (20130101) A01H 6/4684 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813698 | Trayanova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Kathleen McDowell (Baltimore, Maryland) |
| ABSTRACT | Methods, system, and media for identifying one or more ablation locations in an atrial tissue region in an atrial fibrillation (AF) patient with atrial fibrosis are disclosed. Three-dimensional imaging data representing the atria of the patient may be received. A patient-specific model of the atria may be generated from the three-dimensional imaging data. Simulation of the AF on the patient-specific model may be conducted to identify AF-perpetrating regions. One or more ablation locations in the atria may be identified from the AF-perpetrating regions. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 15/814053 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2018/00351 (20130101) A61B 2034/101 (20160201) A61B 2034/104 (20160201) A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813956 | Kaznessis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Yiannis J. Kaznessis (New Brighton, Minnesota); Katherine G. Volzing (Princeton, New Jersey); Juan Borrero Del Pino (Cork, Ireland); Gary Dunny (Minneapolis, Minnesota) |
| ABSTRACT | Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a pheromone-responsive region. In one embodiment, the pheromone-responsive region is derived from a conjugative plasmid from a member of the genus Enterococcus spp. The pheromone-responsive region includes a pheromone-responsive promoter and an operably linked coding region encoding an antimicrobial peptide. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a promoter and an operably linked coding sequence encoding an antimicrobial peptide, where expression of the coding region is controlled by a modulator polypeptide and is altered by a modulating agent, and where the coding region encodes an antimicrobial peptide. Also provided herein are methods of using the genetically modified microbes, including methods for inhibiting growth of an Enterococcus spp., a pathogenic E. coli, or a pathogenic Salmonella spp., for treating a subject, and for modifying a subject's gastrointestinal microflora. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 15/894408 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/744 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 2035/11 (20130101) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814017 | Naczynski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Dominik J. Naczynski (Wallington, New Jersey); Mei-Chee Tan (Singapore, Singapore); Richard E. Riman (Piscataway, New Jersey); Charles Roth (Princeton, New Jersey); Prabhas V. Moghe (Basking Ridge, New Jersey) |
| ABSTRACT | Disclosed is a method of non-invasive infrared imaging, comprising (a) administering a composition containing infrared-emitting particles which contain rare earth elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles; and (b) irradiating with infrared radiation, where both excitation and emission spectra of the encapsulated particles are in the infrared region. Analogous methods of image-guided biomedical intervention, and drug tracking and delivery are also disclosed. Also disclosed is a composition for biomedical applications, containing infrared-emitting particles which contain rare earth-elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/378792 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0075 (20130101) A61B 6/481 (20130101) A61B 6/5247 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0019 (20130101) A61K 49/0065 (20130101) Original (OR) Class A61K 49/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814270 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Kevin Huang (Columbia, South Carolina); Peng Zhang (West Columbia, South Carolina) |
| ABSTRACT | A low-cost and easy-to-fabricate mixed e− and CO32− conducting membrane for advanced high-flux and selective electrochemical CO2 separation from flue gas is provided. The membrane includes a CO32−-conducting molten carbonate phase and an e−-conducting lithiated Ni-oxide interphase that can be formed in situ during operation. The membrane exhibits a CO2 flux density greater than 0.8 mL/(minute·cm2) at 850° C. with a selectivity ranging from about 100 to about 500 and excellent stability for up to about 450 hours. Further, the self-formed interphase Li0.4Ni1.6O2 is highly electron conducting and can provide electrons to the co-reduction of CO2 and O2 into CO32−. Such a membrane is an alternative to the conventional “size-sieving” inorganic and “dissolution-diffusion” organic counterparts for CO2 capture from flue gas. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/975807 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) Original (OR) Class B01D 67/0041 (20130101) B01D 67/0074 (20130101) B01D 67/0083 (20130101) B01D 67/0088 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/141 (20130101) B01D 71/024 (20130101) B01D 2257/104 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2323/08 (20130101) B01D 2325/04 (20130101) B01D 2325/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814348 | Hart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Anastasios John Hart (Woburn, Massachusetts); Justin Douglas Beroz (Gaithersburg, Maryland); Homayoon Maghsoodi (Okemos, Michigan) |
| ABSTRACT | A particle can be discretely ejected from a orifice. |
| FILED | Monday, April 09, 2018 |
| APPL NO | 15/949040 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/006 (20130101) B05B 5/0255 (20130101) B05B 12/06 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/06 (20130101) B05D 1/12 (20130101) Original (OR) Class B05D 3/14 (20130101) B05D 2401/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814529 | Torkelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John M. Torkelson (Skokie, Illinois); Philip Brunner (South Milwaukee, Wisconsin) |
| ABSTRACT | Methods for preparation of polymer materials incorporating various organic components, including but not limited to solid and/or liquid organic wastes, post-consumer refuse and agricultural, commercial and/or manufacturing by-products, using solid-state shear pulverization. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/815868 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815212 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| INVENTOR(S) | Bill J. Baker (Tampa, Florida); Thushara Diyabalanage (Tampa, Florida); James B. McClintock (Birmingham, Alabama); Charles D. Amsler (Pelham, Alabama) |
| ABSTRACT | The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/190679 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815335 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Nathaniel H. Park (San Jose, California); James L. Hedrick (Pleasanton, California); Victoria A. Piunova (Los Gatos, California); Dmitry Zubarev (San Jose, California); Gavin O. Jones (San Jose, California); Robert M. Waymouth (Palo Alto, California); Binhong Lin (Stanford, California) |
| ABSTRACT | Techniques regarding the synthesis of polyesters and/or polycarbonates through one or more ring-opening polymerizations conducted within a flow reactor and facilitated by a urea anion catalyst and/or a thiourea catalyst are provided. For example, one or more embodiments can comprise a method, which can comprise polymerizing, via a ring-opening polymerization within a flow reactor, a cyclic monomer in the presence an organocatalyst comprising a urea anion. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/028919 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 10/00 (20130101) B01J 19/06 (20130101) B01J 19/0013 (20130101) B01J 2219/002 (20130101) B01J 2219/00164 (20130101) B01J 2219/00186 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/785 (20130101) Original (OR) Class C08G 63/912 (20130101) C08G 64/30 (20130101) C08G 64/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815499 | Hjort et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Martin Hjort (Lund, Sweden); Sergio Leal-Ortiz (Hayward, California); Yuhong Cao (Palo Alto, California); Chris Rehse (Palo Alto, California); Andy Kah Ping Tay (Stanford, California); Nicholas A. Melosh (Menlo Park, California) |
| ABSTRACT | Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/038062 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) C12M 23/16 (20130101) C12M 23/42 (20130101) C12M 35/00 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0075 (20130101) C12N 15/87 (20130101) Original (OR) Class C12N 2521/00 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815519 | Husain et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Naeem S Husain (Los Angeles, California); Harry Ming Tak Choi (Arcadia, California); Long Cai (Pasadena, California); Niles A Pierce (Pasadena, California) |
| ABSTRACT | The present disclosure relates to methods involving HCR reactions that involve using trigger oligos to activate probes that initiate HCR. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/689786 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/682 (20130101) C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6804 (20130101) C12Q 1/6825 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/536 (20130101) G01N 33/543 (20130101) G01N 33/54306 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815582 | Busnaina et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Ahmed Busnaina (Needham, Massachusetts); Hanchul Cho (Gyeonggi-do, South Korea); Sivasubramanian Somu (Natick, Massachusetts); Jun Huang (Malden, Massachusetts) |
| ABSTRACT | Damascene templates have two-dimensionally patterned raised metal features disposed on an underlying conductive layer extending across a substrate. The templates are topographically flat overall, and the patterned conductive features establish micron-scale and nanometer-scale patterns for the assembly of nanoelements into nanoscale circuits and sensors. The templates are made using microfabrication techniques together with chemical mechanical polishing. These templates are compatible with various directed assembly techniques, including electrophoresis, and offer essentially 100% efficient assembly and transfer of nanoelements in a continuous operation cycle. The templates can be repeatedly used for transfer of patterned nanoelements thousands of times with minimal or no damage, and the transfer process involves no intermediate processes between cycles. The assembly and transfer processes employed are carried out at room temperature and pressure and are thus amenable to low cost, high-rate device production. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243832 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0042 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/00 (20130101) C25D 13/02 (20130101) Original (OR) Class C25D 15/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/882 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816482 | Sreenivasan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | S. V. Sreenivasan (Austin, Texas); Brian Gawlik (Austin, Texas); Shrawan Singhal (Austin, Texas) |
| ABSTRACT | The present disclosure regards a large area functional metrology system for inspecting nanophotonic devices. The large area functional metrology system can include one or more light sources, optical components such as lenses and polarizers, and one or more camera sensors. The light source can irradiate light onto a nanophotonic device while the optical components can guide the light through the system and modulate states of the light. The camera sensor can record images of the nanophotonic device interacting with the irradiated light. The images can be taken as a function of one or more states. The system can also include a detector which can processes the images in order to detect defects. The defects can then be classified using one or more defect signatures. Based on this classification, the root causes of the defects can be automatically identified. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 15/770095 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/47 (20130101) G01N 21/59 (20130101) G01N 21/95 (20130101) G01N 21/8806 (20130101) G01N 21/8851 (20130101) G01N 21/9501 (20130101) Original (OR) Class G01N 21/95623 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816639 | Przybyla et al. |
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| FUNDED BY |
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| APPLICANT(S) | Chirp Microsystems, Inc. (Berkeley, California) |
| ASSIGNEE(S) | CHIRP MICROSYSTEMS, INC. (Berkeley, California) |
| INVENTOR(S) | Richard J. Przybyla (Emeryville, California); David A. Horsley (Berkeley, California); Mitchell H. Kline (Alameda, California) |
| ABSTRACT | A tracking method is disclosed. The method may include displaying visual content on a screen. A base station may be stationary with respect to the screen while the visual content is being displayed. In contrast, one or more objects may move with respect to the screen while the visual content is being displayed. The one or more objects may be tracked so that the movement thereof may be used to alter the visual content. Such tracking may involve the base station and the one or more objects sending and/or receiving one or more ultrasonic pulses. Time-difference-of-arrival and/or time-of-flight of the one or more ultrasonic pulses may then be used to estimate a relative location and/or a relative orientation of the one or more objects with respect to the base station in three dimensional space. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 16/773691 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/18 (20130101) G01S 5/26 (20130101) Original (OR) Class G01S 5/30 (20130101) G01S 5/0036 (20130101) G01S 5/0263 (20130101) G01S 11/16 (20130101) Electric Digital Data Processing G06F 3/00 (20130101) Wireless Communication Networks H04W 56/0015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818849 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Donglin Zhao (Hyougo, Japan); Qinghe Wu (Chicago, Illinois); Luping Yu (Chicago, Illinois); Zhengxu Cai (Chicago, Illinois) |
| ABSTRACT | The present disclosure relates to α-substituted perylene diimide (PDI) derivatives as small molecular and polymerized electron acceptors in organic photovoltaic cells. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 16/067501 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 519/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/123 (20130101) C08G 61/126 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 3/14 (20130101) C09B 5/62 (20130101) C09B 57/001 (20130101) C09B 69/008 (20130101) C09B 69/102 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/142 (20130101) H01L 51/0032 (20130101) H01L 51/0036 (20130101) H01L 51/42 (20130101) H01L 51/0052 (20130101) H01L 51/0053 (20130101) H01L 51/0056 (20130101) H01L 51/0058 (20130101) H01L 51/0068 (20130101) H01L 51/0071 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/0074 (20130101) H01L 51/0094 (20130101) H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10818914 | Campbell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Brennan Campbell (Reno, Nevada); Robert Ionescu (Sunnyvale, California); Cengiz S Ozkan (San Diego, California); Mihrimah Ozkan (San Diego, California) |
| ABSTRACT | A carbonized mushroom tissue electrode material and methods are shown. In one example, carbonized mushroom tissue is used as an electrode in a battery, such as a lithium ion battery. A battery, comprising: a first electrode, including: carbonized tissue from a mushroom; a second electrode; and an electrolyte in contact with both the first electrode and the second electrode. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/554700 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0471 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 10/0568 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819284 | Han et al. |
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| FUNDED BY |
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| APPLICANT(S) | Guoxiang Han (New York, New York); Tanbir Haque (New York, New York); Peter R. Kinget (Summit, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Guoxiang Han (New York, New York); Tanbir Haque (New York, New York); Peter R. Kinget (Summit, New Jersey) |
| ABSTRACT | Circuits comprising: a plurality of LNTA branches, each comprising: a cascode common-source (CCS) LNTA, a plurality of passive mixers (PMs), and a plurality of baseband two-stage Miller compensated TIAs (BB2S-TIAs); a plurality of mixer-first branches, each comprising: a plurality of RF switches, a plurality of baseband folded-cascode TIAs (BBFC-TIAs), and a plurality of Cherry-Hooper amplifiers, wherein an input to each of the BBFC-TIAs is provided by an output of at least one of the RF switches, and an input to each of the amplifiers is provided by an output of a corresponding one of the BBFC-TIAs; a first plurality of clock modulators that provide first non-overlapping modulated clocks that are provided to an input of the PMs; and a second plurality of clock modulators that provide a plurality of tri-level modulated mixer clocks that control the switching of the RF switches. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/579782 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Demodulation or Transference of Modulation From One Carrier to Another H03D 7/1466 (20130101) Original (OR) Class Amplifiers H03F 1/26 (20130101) H03F 1/0205 (20130101) H03F 3/193 (20130101) H03F 3/45179 (20130101) H03F 3/45403 (20130101) H03F 2200/294 (20130101) H03F 2203/45024 (20130101) Transmission H04B 1/16 (20130101) H04B 1/109 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819468 | Rezazadehreyhani et al. |
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| FUNDED BY |
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| APPLICANT(S) | BLACK LATTICE TECHNOLOGIES, INC. (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ahmad Rezazadehreyhani (San Jose, California); Jonathan C. Hedstrom (Salt Lake City, Utah); Chung Him Yuen (Salt Lake City, Utah); Kohl Riekhof (Cottonwood Heights, Utah); Daryl Wasden (Draper, Utah); Behrouz Farhang (Salt Lake City, Utah) |
| ABSTRACT | Apparatuses, systems, and methods are disclosed for stochastic linear detection. A digital signal processor determines information about a plurality of transmitted signals based on a plurality of received signals. An initialization module determines an estimator matrix and a noise shaping matrix based on channel state information that relates the transmitted signals to the received signals. A sample generation module stochastically generates a plurality of signal estimates so that each signal estimate is a sum of a fixed component and a random component. The fixed component may be based on applying the estimator matrix to a vector of the received signals, and the random component may be based on applying the noise shaping matrix to generated noise. An output module sends soft information to an error-correcting code (ECC) decoder for decoding bits carried by the transmitted signals. The soft information may be based on the plurality of signal estimates. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 16/705206 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1125 (20130101) Transmission H04B 7/0413 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/005 (20130101) Original (OR) Class H04L 1/0054 (20130101) H04L 1/0631 (20130101) H04L 25/067 (20130101) H04L 2025/03426 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819760 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of South Carolina (Los Angeles, California) |
| INVENTOR(S) | Jia Wang (Basking Ridge, New Jersey); Nemmara Shankaranarayanan (Bridgewater, New Jersey); Ajay Mahimkar (Edison, New Jersey); Xing Xu (Seattle, Washington); Ramesh Govindan (Cerritos, California) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, allocating, by a processing system including a processor, a first subset of resources to a first plurality of applications and a second subset of the resources to a second plurality of applications, wherein the allocating is based on respective statuses associated with the first plurality of applications and the second plurality of applications, and assigning, by the processing system, a respective bitrate to each application of the first plurality of applications, wherein the assigning of the respective bitrate to each application of the first plurality of applications is based on: a first threshold associated with a re-buffering of content, and a second threshold associated with the statuses. Other embodiments are disclosed. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148288 |
| ART UNIT | 2425 — Cable and Television |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/01 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 65/604 (20130101) H04L 65/4069 (20130101) Original (OR) Class Wireless Communication Networks H04W 24/08 (20130101) H04W 84/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10814319 | Dasgupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purnendu K. Dasgupta (Arlington, Texas); Weixiong Huang (Arlington, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Purnendu K. Dasgupta (Arlington, Texas); Weixiong Huang (Arlington, Texas) |
| ABSTRACT | Open tubular capillary columns for liquid and ion chromatography, based upon an ionically impermeable polyolefin capillary having a bore with a sulfonate-group- or amine-group-functionalized internal surface. The capillary columns may include a coating of ion exchanging nanoparticles electrostatically bound to the functionalized internal surface. The capillary columns may be made by exposing the interior surface to a sulfonating reagent comprising chlorosulfonic acid (ClSO3H), preferably from 85 wt % to 95 wt % chlorosulfonic acid at a process temperature of 20 to 25° C. The interior surface may be subsequently exposed to an asymmetrical diamine to form a sulfonic mid-linkage to the diamine, i.e., to form a sulfonamide-linked, amine-group-functionalized internal surface. The coating may be provided by subsequently exposing the interior surface to an aqueous suspension of ion exchanging nanoparticles to electrostatically bond the ion exchanging nanoparticles to the functionalized internal surface. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395202 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/22 (20130101) B01D 15/206 (20130101) B01D 15/362 (20130101) B01D 15/363 (20130101) B01D 15/367 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/286 (20130101) B01J 20/3208 (20130101) B01J 20/3242 (20130101) B01J 39/26 (20130101) Original (OR) Class B01J 41/20 (20130101) B01J 47/02 (20130101) B01J 2220/84 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/96 (20130101) G01N 30/6078 (20130101) G01N 2030/567 (20130101) G01N 2030/965 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10814480 | Georgeson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Gary E. Georgeson (Tacoma, Washington); James J. Troy (Tacoma, Washington); Scott W. Lea (Renton, Washington); Daniel James Wright (Mercer Island, Washington) |
| ABSTRACT | Apparatus and methods that can be used to stabilize the distal end of an arm (and an end effector attached thereto) of an automated extended-reach tool-equipped assembly. Stabilization is provided by three or more stabilizers, each comprising a stationary part and a movable part. Each stationary part has a fixed location relative to the end effector; each movable part is translatably coupled to a respective stationary part and comprises a contactor disposed at a distal end of the movable part. When the stabilizers are actuated, the contactors are translated toward and into contact with the surface of the workpiece and then locked in place to stabilize the distal end of the arm and the end effector. During tool operation, the stabilizers reduce oscillation of the end effector (and all structure fixedly coupled thereto). |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878642 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 5/00 (20130101) B25J 5/007 (20130101) B25J 9/109 (20130101) B25J 9/162 (20130101) B25J 9/1015 (20130101) Original (OR) Class B25J 9/1692 (20130101) B25J 9/1697 (20130101) B25J 15/0019 (20130101) B25J 15/0095 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) B64F 5/40 (20170101) B64F 5/60 (20170101) Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 31/02 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/16 (20130101) F41H 11/32 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/39024 (20130101) G05B 2219/40298 (20130101) G05B 2219/45066 (20130101) G05B 2219/45071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815012 | Abrams et al. |
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| FUNDED BY |
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| APPLICANT(S) | Analytical Mechanics Associates, Inc. (Hampton, Virginia) |
| ASSIGNEE(S) | ANALYTICAL MECHANICS ASSOCIATES, INC. (Hampton, Virginia) |
| INVENTOR(S) | John L. Abrams (Englewood, Colorado); Matthew E. Duchek (Boulder, Colorado); Alberto Paz (Littleton, Colorado); Ryan A. Harbach (Lakewood, Colorado); Alexi S. Rakow (Boulder, Colorado) |
| ABSTRACT | Exemplary deployable sheet material systems may be configured to stow and deploy sheet material. The systems may include one or more masts, one or more extendable booms, and one or more guys wires configured to function in conjunction with each other to deploy the sheet material and then to maintain the sheet material in the deployed configuration. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598746 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/44 (20130101) B64G 1/222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815013 | Hasegawa et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Mark M Hasegawa (Highland, Maryland); Kenneth O'Connor (Greenbelt, Maryland); Alfred Wong (Greenbelt, Maryland); George M. Harris (Greenbelt, Maryland); Grant Smith (Greenbelt, Maryland) |
| ABSTRACT | A laminate has a composite coating on a substrate. The substrate is a polymeric substrate with a surface resistivity of 4×102 to 1×108Ω/□; or a textured substrate with surface features which are 100 nm to 10 microns high. The composite coating comprising a tie layer of a nickel-chromium alloy; a layer of a reflective metal; a layer of aluminum oxide; a layer of silicon oxide; and optionally a layer of indium tin oxide. The laminate has a solar absorbance at a wavelength of 0.25 microns to 2.5 microns of between 0.07 and 0.7; and the laminate has an IR emittance of 0.1 to 0.8. Solar absorbance and IR emittance of the laminate may be independently to control the ratio of solar absorbance to IR emittance. Solar absorbance may be adjusted by changing the surface resistance or degree of texturing on the substrate. IR emittance may be adjusted by changing oxide film thickness. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/143732 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/226 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/10 (20130101) C23C 14/20 (20130101) C23C 14/30 (20130101) C23C 14/081 (20130101) C23C 14/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815129 | Youngquist et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Robert C. Youngquist (Cocoa, Florida); Tracy L. Gibson (Melbourne, Florida); Jan M. Surma (Melbourne, Florida); Jerry W. Buhrow (Titusville, Florida); Mark A. Nurge (Oviedo, Florida) |
| ABSTRACT | A rigid radiation reflector is fabricated from a powdered material transparent to light in a wavelength band extending from approximately 0.2 micrometers to at least 8 micrometers. The powdered material is dispersed in a liquid wherein the powdered material is at least 95% insoluble in the liquid. The resulting mixture is molded under pressure at room temperature and then sintered to generate a porous solid. The porous solid is cooled to room temperature. A surface of the porous solid is then coated with a light-reflecting metal. |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/116146 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 3/10 (20130101) Original (OR) Class Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/22 (20130101) C01F 17/206 (20200101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 27/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815474 | Gentry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | USA as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Diana M. Gentry (Atherton, California); Christopher E. Venter (Brisbane, California); Lynn J. Rothschild (Woodside, California) |
| ABSTRACT | This system combines 3D printing technology with artificially modified cells for production of nonliving biomaterials. A 3D printer deposits a 3D array of bioengineered cells in the shape of a selected product. The cells are programmed to produce biomaterials in regulated amounts. The cell array deposits biomaterials onto a substrate. The cells and substrate are then removed, leaving a finished, nonliving product with microscale structure and precision. |
| FILED | Wednesday, July 15, 2015 |
| APPL NO | 14/800238 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 47/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 11/06 (20130101) Original (OR) Class C12N 11/10 (20130101) C12N 11/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815902 | Dardona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Sameh Dardona (South Windsor, Connecticut); Cagatay Tokgoz (Beaumont, Texas) |
| ABSTRACT | A fault detection assembly for an aircraft system according to an example of the present disclosure includes, among other things, a transmitter that communicates an electrical input signal to a first portion of an electrical connector, the first portion moveable between a fully seated position and a fully unseated position relative to a second portion of the electrical connector to define a range of insertion depths, a receiver that senses an electrical output signal relating to the electrical input signal, and a comparison module that determines an insertion depth in the range of insertion depths based on a change in a resonant frequency of the electrical output signal with respect to the electrical input signal. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/844735 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 9/00 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/80 (20130101) F05D 2270/09 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/008 (20130101) G01R 31/69 (20200101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815936 | Garbe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| INVENTOR(S) | Duane J. Garbe (Mendon, Utah); Edward L. Collins (Tremonton, Utah); Allan P. Thompson (Tremonton, Utah) |
| ABSTRACT | A flexible bearing assembly includes at least one metal end ring, a flexible bearing core having a plurality of layers of a resilient material between layers of a reinforcement material, and a phenolic composite material between and bonded to each of the at least one metal end ring and the flexible bearing core. A rocket motor assembly includes a chamber configured to contain a propellant and a movable thrust nozzle coupled to the chamber. The movable thrust nozzle includes a phenolic composite material between and bonded to each of a metal end ring and a flexible bearing core. Methods of forming a flexible bearing assembly include bonding a phenolic composite material to at least one metal end ring and bonding a flexible bearing core to the phenolic composite material. The flexible bearing core includes a plurality of layers of a resilient material between layers of a reinforcement material. |
| FILED | Wednesday, November 09, 2016 |
| APPL NO | 15/347621 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/48 (20130101) B29C 65/1403 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/04 (20130101) Jet-propulsion Plants F02K 9/80 (20130101) F02K 9/84 (20130101) F02K 9/86 (20130101) Original (OR) Class F02K 9/97 (20130101) F02K 9/343 (20130101) F02K 9/978 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/23 (20130101) F05D 2240/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816209 | Cheung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Albert K. Cheung (East Hampton, Connecticut); James B. Hoke (Tolland, Connecticut); Randal G. McKinney (Ellington, Connecticut) |
| ABSTRACT | A fuel injection system may comprise a mixer and a fuel injector disposed within the mixer. The mixer may comprise an outer housing with an exit port and a bluff body extending across the exit port of the outer housing. A flared surface of the mixer may match a contour of the bluff body. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 15/708892 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/04 (20130101) B01F 15/0274 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/22 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 61/162 (20130101) Burners F23D 11/383 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/34 (20130101) F23R 3/286 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816383 | Blackmon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James B. Blackmon (Brownsboro, Alabama) |
| ASSIGNEE(S) | Board of Trustees of the University of Alabama (Huntsville, Alabama) |
| INVENTOR(S) | James B. Blackmon (Brownsboro, Alabama) |
| ABSTRACT | The present disclosure generally pertains to devices and methods for determining propellant mass based on average measurements irrespective of the fluid orientation in a fuel tank. The device is useful in detecting fuel levels in tanks where the fuel is in motion, for instance in aircraft (i.e., undergoing varying acceleration maneuvers) or spacecraft (i.e., a microgravity environment). The devices and methods can also be used for determining the liquid in a surface tension screen liquid acquisition device (LAD), and particularly, the incipient breakdown as gas bubbles enter or are formed inside the LAD as the screen dries or heat transfer induces vaporization. The same basic electrode configuration can be used to stir the liquid to reduce thermal stratification and condense vapor bubbles. |
| FILED | Friday, March 13, 2015 |
| APPL NO | 14/657860 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/263 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816411 | Meyyappan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Meyya Meyyappan (San Jose, California); Jin-Woo Han (San Jose, California) |
| ABSTRACT | A microheater performs a self measurement of its own temperature. The microheater has an electrically resistive element which generates heat when a voltage has been applied across the resistive element. The resistive element has an electrical conductivity that is a function of its temperature. A measurement device is positioned within the microheater body and is configured to measure conductivity of the resistive element. An electronic processor, that may be incorporated into the microheater, controls brief interruption of the heating voltage and application of a lower voltage for measuring conductivity. The lower voltage is insufficient to increase the heat output of the microheater, and is applied for too short of a period to allow excessive cooling of the microheater. A microprocessor receives and processes the data obtained from measuring conductivity. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/697322 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/183 (20130101) Original (OR) Class G01K 7/186 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816420 | Litteken et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Douglas A Litteken (Houston, Texas); Jared S Daum (Houston, Texas) |
| ABSTRACT | A tension-measurement device configured to determine a tension in a line includes a body. The body includes a first portion, a second portion extending from the first portion of the body, and a third portion extending from the first portion of the body. The line is configured to extend at least partially through the second and third portions of the body. A first sensor is coupled to the body and is configured to measure a strain on the body when a first portion of the line is placed under tension. The tension in the first portion of the line is configured to be determined based at least partially upon the strain. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946265 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816463 | Numata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Kenji Numata (College Park, Maryland); Haris Riris (Arlington, Virginia); Stewart T. Wu (Ellicott City, Maryland); Xiaoli Sun (Bethesda, Maryland) |
| ABSTRACT | A laser spectrometer includes a tunable laser assembly, a periodically-poled nonlinear optical crystal, with parallel polished input and output end faces, and a mechanism for controlling an entrance location of a pump input beam of the tunable laser on the input end face of the periodically-poled nonlinear optical crystal, such that the pump input beam traverses different grating periods of the periodically-poled nonlinear optical crystal. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/059850 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) G01N 21/39 (20130101) Original (OR) Class G01N 21/3504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816704 | Arbabi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Amir Arbabi (Pasadena, California); Andrei Faraon (La Canada Flintridge, California) |
| ABSTRACT | An optical device has a first metasurface. A high-contrast pattern of the first metasurface is operable for modifying, over a first phase profile, a phase front of an incident light beam. A second metasurface, is disposed over a plane parallel to the first metasurface with a second high-contrast pattern and operable for shaping, over a second phase profile, the modified phase front of the incident light beam into a converging spherical phase front. A spacer layer, in which the modified phase front of the incident light beam diffracts, is disposed in a controllably changeable separation between the first and second metasurfaces. Controllably changing the separation between the first and the second metasurfaces by a first distance correspondingly changes the position of the focus point of the converging spherical phase front by a second distance. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/970658 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 3/0087 (20130101) G02B 5/18 (20130101) G02B 5/1828 (20130101) Original (OR) Class G02B 5/1842 (20130101) G02B 5/1847 (20130101) G02B 7/08 (20130101) G02B 27/4277 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 3/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49844 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819080 | Numata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Kenji Numata (Greenbelt, Maryland); Anthony Yu (Greenbelt, Maryland) |
| ABSTRACT | Coating-less nonplanar ring oscillator lasers are disclosed. Such lasers may eliminate the need for thin-film optical coatings from a laser cavity, solving the problem of optical damage to the coatings, and thus, providing a longer useful lifetime for the laser for space or terrestrial applications. Such lasers may be compact, ultra-stable, and highly reliable, enabling a low phase noise, single frequency laser in a compact package. Such lasers may be used in CW and/or in pulse mode. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540796 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/101 (20130101) H01S 3/0615 (20130101) H01S 3/0627 (20130101) Original (OR) Class H01S 3/1611 (20130101) H01S 3/1643 (20130101) H01S 3/09415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819364 | Suarez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Adminstrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | George Suarez (Greenbelt, Maryland); Jeffrey Dumonthier (Greenbelt, Maryland); Nikolaos Paschalidis (Greenbelt, Maryland) |
| ABSTRACT | A radiation hardened, digital to analog converter includes first and second serial communication circuits, a common bus interface configured to connect the first and second serial communication circuits to first and second digital serial communication buses, respectively, and a digital to analog converter circuit, where the first and second serial communication circuits are configured to receive data over the first and second digital serial communication buses, respectively, for use by the digital to analog converter circuit. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514089 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Transmission Systems for Measured Values, Control or Similar Signals G08C 15/00 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/463 (20130101) Coding; Decoding; Code Conversion in General H03M 1/0607 (20130101) H03M 1/687 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819454 | Schemmel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Adminstrator of National Aeronautics and Space Adminstration (Washington, District of Columbia) |
| INVENTOR(S) | Peter J. Schemmel (Fairview Park, Ohio) |
| ABSTRACT | Vortex radiometers (VRs) for cognitive antenna applications and fade prediction techniques are disclosed. A VR may act as an early warning system for communication antennas by of measuring: (1) when a fade causing interference with or complete loss of communication signal will occur; (2) how long the fade will persist; and/or (3) how intense the fade will be. This may be accomplished by measuring atmospheric noise temperature with concentric annular antenna beam patterns. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/697369 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/36 (20130101) Transmission H04B 7/18513 (20130101) H04B 17/3911 (20150115) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10815536 | Lipkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Walter Ian Lipkin (New York, New York); Omar Jabado (Philadelphia, Pennsylvania); Thomas Briese (White Plains, New York); Amit Kapoor (Columbus, Ohio); Jan Gogarten (Berlin, Germany); Komal Jain (New York, New York); Nischay Mishra (New York, New York) |
| ABSTRACT | The present invention provides novel methods, systems, tools, and kits for the simultaneous detection, identification and/or characterization of all viruses known or suspected to infect vertebrates. The methods, systems, tools, and kits described herein are based upon the virome capture sequencing platform (“VirCapSeq-VERT”), a novel platform developed by the inventors. The invention also provides methods and kits for designing and constructing of the virome capture sequencing platform. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/759937 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1006 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class C12Q 2535/122 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 50/14 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815878 | Rainey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Shane R. J. Rainey (New London, Connecticut); Thomas C. Rodzewicz (New London, Connecticut); Julian J. Blanco (New London, Connecticut); Ryan T. Ostrander (New London, Connecticut) |
| ABSTRACT | A homogeneous charge compression ignition free-piston linear generator is disclosed. The linear generator includes a housing having cylinders at opposite ends. A double-ended piston assembly is to move linearly in the housing to convert kinetic energy of the piston assembly into electrical energy, and to enable conversion of electrical energy into kinetic energy of the piston assembly. Sensors measure one or more states of the cylinders and/or piston assembly, and a controller controls the linear generator based on the sensor data. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915877 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines or Engines, in General or of Positive-displacement Type, e.g Steam Engines F01B 11/02 (20130101) F01B 11/004 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 1/14 (20130101) F02B 47/02 (20130101) F02B 63/041 (20130101) Original (OR) Class F02B 71/00 (20130101) F02B 75/24 (20130101) F02B 2075/1808 (20130101) Controlling Combustion Engines F02D 13/0215 (20130101) F02D 15/00 (20130101) F02D 41/009 (20130101) F02D 41/34 (20130101) F02D 41/1443 (20130101) F02D 41/3035 (20130101) F02D 2041/001 (20130101) F02D 2200/021 (20130101) F02D 2200/024 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 25/03 (20130101) F02M 25/025 (20130101) Starting of Combustion Engines; Starting Aids for Such Engines, Not Otherwise Provided for F02N 11/04 (20130101) Dynamo-electric Machines H02K 7/1884 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/00 (20130101) H02P 9/04 (20130101) H02P 25/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816530 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jude Aaron Kelley (Bolton, Massachusetts); Richard Paul Kingsborough (Groton, Massachusetts); Roderick Russell Kunz (Acton, Massachusetts) |
| ABSTRACT | Methods and reagents are disclosed for improved detection of inorganic oxidizers, such as but not limited to chlorates, perchlorates, permanganates, dichromates, and osmium tetraoxides. In one aspect of the invention, latent acid-generating reagents are employed that are chemically stable at room temperature but undergo an acidic transformation when exposed to an elevated temperature or radiation. The latent reagent can be activated by heat or radiation (e.g., UV radiation). The resulting acidic reagent can then transfer a proton to the anion (i.e., chlorate, perchlorate, etc.) of the target analyte, forming an acid (i.e., chloric acid, perchloric acid) that is more easily vaporized and, hence, more easily detected. In another aspect of the invention, heat-sensitive inorganic salts and/or photosensitive onium salts are disclosed as reagents to carry out this method. In various embodiments, these reagents can be embedded in a swipe or other substrate, infused onto the swipe or sample via nebulizer, or otherwise deployed in a desorption chamber of an ion mobility spectrometer or similar detector. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/687010 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 27/622 (20130101) G01N 33/227 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/19 (20150115) Y10T 436/24 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10817738 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Various example implementations of the present invention are directed towards systems and methods to quantify biometric acquisition and identification. A test facility evaluates the acquisition by a biometric station of biometric information. Evaluations can relate to biometric information acquisition speed, rates of acquisition failure, rates of biometric information extraction failure, rates of biometric match failure, calculating a true identification rate, and/or calculating other metrics related to quantifying biometric acquisition and identification. The test facility can calculate an efficiency metric and an effectiveness metric of the quantification determinations, and output such results. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/150773 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/036 (20130101) Original (OR) Class G06K 9/00885 (20130101) G06K 9/6201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10813656 | Aslinia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Florence M. Aslinia (Bloomington, Indiana); Eric Goldberg (Dayton, Maryland); Chad Schneider (Owings Mills, Maryland) |
| ABSTRACT | Provided herein are expandable endoscopic devices. In accordance with certain aspects of an embodiment of the invention, an endoscopic expandable device is disclosed that comprises an expandable jaw at the distal tip, a control wire connected to the jaw, a sheath enclosing the control wire, and a handle connected to the sheath or wire having an actuating trigger. The expandable jaw is configured to allow its delivery in a retracted configuration to a target site within a patient's body through the working channel of an endoscope, after which the jaw may reconfigure to an expanded configuration that is larger than the retracted configuration. This allows the expandable jaw to be easily delivered to the target site while allowing an operable jaw size that is larger than would be allowed if limited to size of the working channel. The endoscopic expandable device may have utility as a clip or as forceps. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/188961 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/04 (20130101) A61B 10/06 (20130101) A61B 17/10 (20130101) A61B 17/29 (20130101) Original (OR) Class A61B 17/1227 (20130101) A61B 17/1285 (20130101) A61B 17/22031 (20130101) A61B 2017/00269 (20130101) A61B 2017/00287 (20130101) A61B 2017/2215 (20130101) A61B 2017/2926 (20130101) A61B 2017/2931 (20130101) A61B 2017/2947 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813770 | Cavanagh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Peter R. Cavanagh (Seattle, Washington); William R. Ledoux (Seattle, Washington); Bruce J. Sangeorzan (Seattle, Washington) |
| ABSTRACT | The present technology relates generally to devices and methods for arthroplasty procedures. In some embodiments, for example, a device is disclosed for use during an arthroplasty procedure of a joint of a patient, the joint extending between a first joint end of a first bone and an abutting second joint end of a second bone of the patient. The device includes an end plate configured and arranged for disposing over the first joint end of the first bone, a longitudinal plate extending from the end plate and configured and arranged for disposing along a medial, longitudinal surface of the first bone, and a stem extending from the end plate and suitable for extending along an intra-medullary canal of the first bone. When installed, at least one fastener extends at least partially through the first bone and couples the longitudinal plate to the first bone. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 15/542009 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/4225 (20130101) Original (OR) Class A61F 2002/4233 (20130101) A61F 2002/30578 (20130101) A61F 2002/30878 (20130101) A61F 2002/30902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813913 | Sanchez-Ramos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Juan Sanchez-Ramos (Plant City, Florida); Vasyl Sava (Wesley Chapel, Florida); Shijie Song (Tampa, Florida); Said Sebti (Tampa, Florida) |
| ABSTRACT | Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial agonists/antagonists of G-CSF. Further provided herein are methods of treating a condition, including, for example, a neurodegenerative disease, by administering a compound as detailed herein. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388661 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/4174 (20130101) Original (OR) Class A61K 38/193 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 233/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815285 | Gemma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carmelina Gemma (Bellevue, Washington); Paula C. Bickford (Ruskin, Florida); Kevin R. Nash (Seffner, Florida); Josh Morganti (Richmond, California); Adam Bachstetter (Lexington, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Carmelina Gemma (Bellevue, Washington); Paula C. Bickford (Ruskin, Florida); Kevin R. Nash (Seffner, Florida); Josh Morganti (Richmond, California); Adam Bachstetter (Lexington, Kentucky) |
| ABSTRACT | The subject invention pertains to the use of fractalkine (FKN, CX3CL1) and its receptor CX3CR1 for treatment of neuroinflammation and/or neurodegeneration. In one embodiment, the present invention provides a method for treatment of neuroinflammation and/or neurodegenerative diseases, comprising: administering, to cells of a subject in need of such treatment, an adeno-associated virus that comprises a functional fractalkine gene operably linked to transcriptional control elements. In one embodiment, the subject invention is used to treat or ameliorate Parkinson's disease. The present invention can also be used to treat or ameliorate neuroinflammatory and/or neurodegenerative diseases including, but not limited to, Alzheimer's disease, epilepsy, aging, and traumatic brain injury. |
| FILED | Saturday, June 30, 2012 |
| APPL NO | 14/126708 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Peptides C07K 14/521 (20130101) Original (OR) Class C07K 14/7158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10813323 | Kindiger |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Bryan K. Kindiger (El Reno, Oklahoma) |
| ABSTRACT | The tall fescue DH66OP Accession No. PI 690020 represents a genetic stock possessing an L. multiflorum cytoplasm that can enhance or induce rhizome formation across various genotypes. DH66OP may allow for the transfer the L. multiflorum cytoplasm to additional tall fescue genotypes for the recovery of genotypes expressing rhizomes. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 16/510321 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) A01H 6/463 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10813324 | Koch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Karen Elaine Koch (Gainesville, Florida); Sylvia Morais De Sousa (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Karen Elaine Koch (Gainesville, Florida); Sylvia Morais De Sousa (Gainesville, Florida) |
| ABSTRACT | The subject invention concerns materials and methods for modulating seed size in plants. In one embodiment, seed size is decreased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed size is increased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. The subject invention also concerns materials and methods for modulating seed number or sugar content in plants. In one embodiment, seed number or sugar content is increased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed number or sugar content is decreased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. |
| FILED | Monday, May 19, 2008 |
| APPL NO | 12/599652 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/00 (20130101) A01H 5/10 (20130101) A01H 6/4684 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815491 | Baerson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Scott R. Baerson (Oxford, Mississippi); Zhiqiang Pan (Oxford, Mississippi); James J Polashock (Hainesport, New Jersey) |
| ABSTRACT | Transcription regulatory elements, namely promoter and terminator sequences, obtained from Sorghum bicolor that drive RNA transcription predominately in root hair cells are described, as well as cassettes, expression vectors, and genetically modified plants containing these transcription regulatory elements. The genetically modified plants can be gymnosperms, dicots, or monocots. Methods of directing transcription of a heterologous polynucleotide under control of these transcription regulatory elements in a genetically modified plant's root hair cells are also provided. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978821 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10815070 | Bouchard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Austin C. Bouchard (Washington, District of Columbia); Alexander S. Klinger (Silver Spring, Maryland) |
| ABSTRACT | A device, system, and method for detecting a covering sleeve on a container. A sleeve detection system includes a conveyor, a height profile acquisition device, and a processor in communication with the height profile acquisition device. The height profile acquisition device is configured to acquire height profiles of a tray traveling on the conveyor. The processor is configured to analyze height profiles received from the height profile acquisition device to determine a sleeve status of the tray. In some embodiments, a light gate is disposed across the conveyor and configured to detect the presence of a tray on the conveyor approaching the height profile acquisition device. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/716255 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 57/02 (20130101) B65B 69/00 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 13/00 (20130101) B65G 43/08 (20130101) Original (OR) Class B65G 47/53 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/0608 (20130101) G01B 17/00 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815083 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | John W. Brown (Manassas, Virginia); Edward F. Houston (Bristow, Virginia); Juan A. Roman (Fairfax, Virginia); Leung M. Shiu (Gaithersburg, Maryland); Riley H. Mayhall (Germantown, Maryland); Thomas A. Hillerich, Jr. (Louisville, Kentucky); Jacob L. Timm (Pasadena, Maryland); Matthew G. Good (Eldersburg, Maryland); William P. McConnell (Woodstock, Maryland); Robert L. Schlender (Columbia, Maryland); Christopher D. Austin (Parkville, Maryland) |
| ABSTRACT | Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/989039 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 47/06 (20130101) B65G 47/28 (20130101) B65G 47/46 (20130101) B65G 59/04 (20130101) Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 3/46 (20130101) B65H 3/124 (20130101) Original (OR) Class B65H 5/24 (20130101) B65H 5/224 (20130101) B65H 7/12 (20130101) B65H 2220/09 (20130101) B65H 2220/09 (20130101) B65H 2301/321 (20130101) B65H 2404/2691 (20130101) B65H 2406/32 (20130101) B65H 2406/32 (20130101) B65H 2701/1916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819694 | Moran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Timothy M. Moran (National Harbor, Maryland); Jane E. Quenk (Washington, District of Columbia); Douglas Paul Glair (Baltimore, Maryland); Charles P. McLellan (Washington, District of Columbia) |
| ABSTRACT | A system and method of validating an upgrade of authentication credentials includes authenticating a first user being associated with a first entity, receiving input identifying a customer name for the online account, receiving input indicating a type of identification to be presented at the validation event, receiving input indicating a transaction code associated with the validation event, and receiving input indicating a location of the validation event, and further includes authenticating a second user being associated with a second entity, providing to the second user a list of validation events for a location, receiving input selecting a validation event in the list of validation events, presenting one or more of the customer name, transaction code, and type of identification associated with the selected validation event, and receiving input indicating a result of the validation event, where a credential or token is created and assigned based on the validation event. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700899 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) Original (OR) Class H04L 63/083 (20130101) H04L 63/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10815499 | Hjort et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Martin Hjort (Lund, Sweden); Sergio Leal-Ortiz (Hayward, California); Yuhong Cao (Palo Alto, California); Chris Rehse (Palo Alto, California); Andy Kah Ping Tay (Stanford, California); Nicholas A. Melosh (Menlo Park, California) |
| ABSTRACT | Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/038062 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) C12M 23/16 (20130101) C12M 23/42 (20130101) C12M 35/00 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0075 (20130101) C12N 15/87 (20130101) Original (OR) Class C12N 2521/00 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10816325 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Zeeshan Ahmed (Washington, District of Columbia); Kevin O. Douglass (Ellicott City, Maryland); Stephen P. Eckel (Rockville, Maryland); Patrick F. Egan (Rockville, Maryland); Jay H. Hendricks (Clarksburg, Maryland); Jack A. Stone, Jr. (Silver Spring, Maryland) |
| ABSTRACT | A deformometer includes: a cavity body; entry and exit optical cavity optics, such that the optical cavity produces filtered combined light from combined light; a first laser that provides first light; a second laser that provides second light; an optical combiner that: receives the first light; receives the second light; combines the first light and the second light; produces combined light from the first light and the second light; and communicates the combined light to the entry optical cavity optic; a beam splitter that: receives the filtered combined light; splits the filtered combined light; a first light detector in optical communication with the beam splitter and that: receives the first filtered light from the beam splitter; and produces a first cavity signal from the first filtered light; and a second light detector that: receives the second filtered light; and produces a second cavity signal from the second filtered light. |
| FILED | Wednesday, July 24, 2019 |
| APPL NO | 16/520672 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 27/283 (20130101) G02B 27/1006 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/23 (20130101) H01S 3/107 (20130101) H01S 3/1625 (20130101) H01S 3/1636 (20130101) H01S 3/2222 (20130101) H01S 5/4012 (20130101) H01S 5/4075 (20130101) H01S 5/4087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10817291 | Corbal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jesus Corbal (King City, Oregon); Rohan Sharma (Hillsboro, Oregon); Simon Steely, Jr. (Hudson, New Hampshire); Chinmay Ashok (Beaverton, Oregon); Kent D. Glossop (Nashua, New Hampshire); Dennis Bradford (Portland, Oregon); Paul Caprioli (Forest Grove, Oregon); Louise Huot (Hillsboro, Oregon); Kermin ChoFleming (Hudson, Massachusetts); Barry Tannenbaum (Nashua, New Hampshire) |
| ABSTRACT | Systems, methods, and apparatuses relating to swizzle operations and disable operations in a configurable spatial accelerator (CSA) are described. Certain embodiments herein provide for an encoding system for a specific set of swizzle primitives across a plurality of packed data elements in a CSA. In one embodiment, a CSA includes a plurality of processing elements, a circuit switched interconnect network between the plurality of processing elements, and a configuration register within each processing element to store a configuration value having a first portion that, when set to a first value that indicates a first mode, causes the processing element to pass an input value to operation circuitry of the processing element without modifying the input value, and, when set to a second value that indicates a second mode, causes the processing element to perform a swizzle operation on the input value to form a swizzled input value before sending the swizzled input value to the operation circuitry of the processing element, and a second portion that causes the processing element to perform an operation indicated by the second portion the configuration value on the input value in the first mode and the swizzled input value in the second mode with the operation circuitry. |
| FILED | Saturday, March 30, 2019 |
| APPL NO | 16/370915 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30036 (20130101) Original (OR) Class G06F 9/30145 (20130101) G06F 15/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820057 | Eberle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
| INVENTOR(S) | Hans Eberle (Mountain View, California); Larry Robert Dennison (Mendon, Massachusetts) |
| ABSTRACT | A communication method between a source device and a target device utilizes speculative connection setup between the source device and the target device, target-device-side packet ordering, and fine-grained ordering to remove packet dependencies. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376988 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/20 (20130101) H04L 45/7453 (20130101) H04L 47/283 (20130101) H04L 47/624 (20130101) Pictorial Communication, e.g Television H04N 21/2387 (20130101) H04N 21/4302 (20130101) H04N 21/6583 (20130101) H04N 21/23406 (20130101) H04N 21/47217 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 10819510 | Alwen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wickr Inc. (San Francisco, California) |
| ASSIGNEE(S) | Wickr Inc. (Pleasanton, California) |
| INVENTOR(S) | Joël Alwen (Vienna, Austria) |
| ABSTRACT | The present application describes a method, system, and non-transitory computer-readable medium for exchanging encrypted communications using hybrid cryptography protocol. According to the present disclosure, a first device divides a first communication into at least a first secret and a second secret. The first device encrypts the first secret using a first cipher suite and the second secret using a second cipher suite. The first device generates a first signature of the first encrypted secret and the second encrypted secret according to a first signature generation algorithm associated with the first cipher suite and a second signature of the first encrypted secret and the second encrypted secret according to a second signature generation algorithm associated with the second cipher suite. The first device transmits the first encrypted secret and the second encrypted secret, the first signature, and the second signature to the second device. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889337 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/085 (20130101) Original (OR) Class H04L 9/0822 (20130101) H04L 9/0844 (20130101) H04L 9/0852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10815137 | Jolly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clifford D. Jolly (Parker, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clifford D. Jolly (Parker, Colorado) |
| ABSTRACT | A system and method for delivering silver ion biocide is described herein. The systems described relate to passing water from a water system through a silver ion release module and optional high-concentration silver ion release module. The system includes an analyzer, detector, and/or controller for monitoring the concentration of silver ion and adjusting the flow path, flow rate, temperature and/or pH of the water in order to obtain the desired concentration of silver ion. The system optionally includes other metal ions released into a water system, the concentration of which may be used to automatically calibrate the described system and/or cause the system to take actions based on the measured concentration of silver ion or of the second metal ion. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/056355 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/505 (20130101) Original (OR) Class C02F 1/687 (20130101) C02F 1/688 (20130101) C02F 1/4606 (20130101) C02F 1/4672 (20130101) C02F 2201/4612 (20130101) C02F 2209/001 (20130101) C02F 2209/02 (20130101) C02F 2209/003 (20130101) C02F 2209/006 (20130101) C02F 2209/06 (20130101) C02F 2209/36 (20130101) C02F 2209/40 (20130101) C02F 2301/043 (20130101) C02F 2303/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815356 | Bullock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Steven Edward Bullock (Canton, Georgia); Jaime Ballester (Newhall, California) |
| ABSTRACT | A gas barrier material includes an atomic sheet, such as graphene and/or an analog of graphene. The gas barrier material can be arranged as part of a component, such as a container or other vessel, to limit the flow or permeation of gas through the component. Where the component is a container or part of a container, the gas barrier material may be formulated and arranged to limit or prevent gas ingress or egress with respect to the internal volume of the container. The atomic sheet offers improved gas barrier properties compared to traditional polymeric barrier materials and is particularly useful in applications where it is desired to limit permeation of small gas molecules such as helium, such as airships or other lighter than air vehicles. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 15/418564 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/28 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/02 (20130101) B32B 1/08 (20130101) B32B 5/16 (20130101) Lighter-than Air Aircraft B64B 1/02 (20130101) B64B 1/40 (20130101) B64B 1/58 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 25/14 (20130101) B65D 65/42 (20130101) B65D 81/263 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/28 (20130101) C08K 3/042 (20170501) Original (OR) Class C08K 9/00 (20130101) C08K 9/02 (20130101) C08K 2003/385 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 7/61 (20180101) C09D 7/62 (20180101) C09D 7/70 (20180101) C09D 127/08 (20130101) C09D 127/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/19 (20150115) Y10T 428/24752 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815809 | DiFrancesco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael L. DiFrancesco (Waterbury, Connecticut); Conway Chuong (Manchester, Connecticut) |
| ABSTRACT | An outer seal structure for a rotor assembly includes a stator structure and a non-contact seal assembly. The non-contact seal assembly is fixed relative to the stator structure and includes a plurality of seal shoes, a seal base, a plurality of spring elements, and a shoe support plate. The plurality of seal shoes are arranged about an axis in an annular array. The seal base circumscribes the annular array of the plurality of seal shoes. Each of the plurality of spring elements extend radially between a respective seal shoe of the plurality of seal shoes and the seal base. The shoe support plate is arranged about the axis and mounted to the stator structure and includes a plurality of shoe support tabs extending axially from the shoe support plate. Each shoe support tab of the plurality of shoe support tabs is disposed between each seal shoe. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149901 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) Original (OR) Class F01D 11/025 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/57 (20130101) F05D 2260/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815820 | Pratt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | William S. Pratt (West Hartford, Connecticut); Ryan M. Stanley (Quaker Hill, Connecticut); Adam Hart (East Hampton, Connecticut) |
| ABSTRACT | A synchronizing assembly including: a synchronizing ring having a countersunk orifice; and a bumper assembly comprising: a bumper at least partially enclosing a cavity, the bumper comprising an outward side, an inward side opposite the outward side, a first side extending between the outward side and the inward side, a first opening on the outward side extending into the bumper to define a first portion of the cavity; and a second opening on the first side extending into the bumper to define a second portion of the cavity; and a bolt comprising a bolt head and a bolt shank, wherein the bolt shank extends through the first opening and the bolt head is secured within the second portion of the cavity, wherein the bumper further comprises a raised boss extending away from the outward surface, the raised boss configured to mate with the countersunk orifice of the synchronizing ring. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267581 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Original (OR) Class F01D 25/243 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/20 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2260/50 (20130101) F05B 2270/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815822 | Dickens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jeffrey D. Dickens (Palm Beach Gardens, Florida); Brian K. Richardson (Jupiter, Florida); Russell B. Hanson (Jupiter, Florida) |
| ABSTRACT | A system for an engine defined about an axial centerline includes an inner case that includes a bushing, a duct case radially outward of the inner case with respect to the axial centerline, and a seal located on the duct case. The system further includes a borescope plug assembly that traverses the seal and the bushing in mounting to the inner case. The borescope plug assembly includes a spring, a housing sleeve, and a washer sleeve at least partially nested within the housing sleeve. The spring is isolated from the seal by the housing sleeve and the washer sleeve such that the spring is contact-free with respect to the seal. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995972 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/14 (20130101) F05D 2240/55 (20130101) F05D 2260/83 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10815832 | Staffier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Peter Staffier (Wilbraham, Massachusetts); Paul W. Palmer (South Glastonbury, Connecticut); Anders C. Olson (Bloomfield, Connecticut); Nicholas W. Kantany (Manchester, Connecticut); Eric Baker (Vernon, Connecticut) |
| ABSTRACT | A turbine exhaust case is provided for a gas turbine engine. This turbine exhaust case includes a first gas turbine engine exhaust case, a second gas turbine engine exhaust case, a strut and a fastener. The second gas turbine engine exhaust case includes a flange and a bracket. The strut is coupled to the first case and the second case. The fastener fastens the flange and the strut. The second gas turbine engine exhaust case is co-axial with the first gas turbine engine exhaust case. The strut contacts the bracket when the engine is powered-on. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012396 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/005 (20130101) F01D 25/30 (20130101) F01D 25/243 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/14 (20130101) F05D 2300/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10819387 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland); Andrew Keith Palmisano (Laurel, Maryland); Kregg Elliott Arms (Columbia, Maryland); Audrey Nichole Moore (Stevensville, Maryland) |
| ABSTRACT | Techniques of transmitting wireless communications involve generating orthogonal spreading codes for any number of user devices that are linear combinations of sinusoidal harmonics that match the frequencies within the spread bandwidth. Along these lines, prior to transmitting signals, processing circuitry may generate a set of initial code vectors that form an equiangular tight frame having small cross-correlations. From each of these rows, the processing circuitry produces a new spreading code vector using a code map that is a generalization of a discrete Fourier transform. The difference between the code map and a discrete Fourier transform is that the frequencies of the sinusoidal harmonics are chosen to match the particular frequencies within the spread bandwidth and differ from a center frequency by multiples of the original unspread bandwidth. Different transmitters may then modulate respective signals generated with different spreading code vectors. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/690769 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/707 (20130101) Original (OR) Class Multiplex Communication H04J 13/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 27, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201027.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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