FedInvent™ Patents
Patent Details for Tuesday, November 03, 2020
This page was updated on Monday, March 27, 2023 at 06:13 AM GMT
Department of Health and Human Services (HHS)
| US 10820817 | Plenz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Defense, Armed Forces Institute of Pathology (Bethesda, Maryland) |
| INVENTOR(S) | Dietmar Plenz (Chevy Chase, Maryland); Oren Shriki (Rockville, Maryland); Giulio Tononi (Verona, Wisconsin); Christian Meisel (Washington, District of Columbia) |
| ABSTRACT | The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent (α) or branching parameter (σ) from a predetermined value at rest, wherein the pre-determined value of α is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is −3/2 and the pre-determined value of σ is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject. |
| FILED | Friday, August 15, 2014 |
| APPL NO | 14/912392 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0478 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 5/04017 (20130101) A61B 5/4806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820818 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bin He (Arden Hills, Minnesota); Zhaoye Zhou (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for non-invasively generating a report of cardiac electrical activities of a subject includes determining, using cardiac electrical activation information, equivalent current densities (ECDs). The ECDs are assembled into time-course ECD information and a spectrum of the time-course ECD information is analyzed to determine peaks for spectral characteristics of atrial fibrillation (AF). The spectral characteristics of AF are correlated with potential electrical sources of the AF and a report is generated indicating the potential electrical sources of the AF spatially registered with the medical imaging data. |
| FILED | Wednesday, January 18, 2017 |
| APPL NO | 15/409395 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/0044 (20130101) A61B 5/046 (20130101) A61B 5/055 (20130101) A61B 5/0432 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/7278 (20130101) A61B 5/7289 (20130101) A61B 6/032 (20130101) A61B 6/507 (20130101) A61B 2576/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820844 | Scherer et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Axel Scherer (Barnard, Vermont); Arti Gaur (Hanover, New Hampshire) |
| ABSTRACT | Wireless electrochemical measurements methods using minimally invasive micro-sensors that monitor response of cells to specific analytes are described. Micro-actuators integrated on a same chip as the micro-sensors are used to provide closed loop in-vivo local therapy on demand. An in-vivo bio-electronic system that can monitor the health of cell colonies and accordingly dispense corresponding therapeutic drugs is also described. |
| FILED | Thursday, July 21, 2016 |
| APPL NO | 15/216662 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/1451 (20130101) A61B 5/1459 (20130101) A61B 5/1473 (20130101) Original (OR) Class A61B 5/4839 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14735 (20130101) A61B 5/14865 (20130101) A61B 17/3468 (20130101) A61B 2560/0219 (20130101) A61B 2562/04 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/172 (20130101) A61M 5/1723 (20130101) A61M 5/14276 (20130101) A61M 2205/3523 (20130101) A61M 2205/8237 (20130101) A61M 2207/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820847 | Andeshmand et al. |
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| FUNDED BY |
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| APPLICANT(S) | Talis Biomedical Corporation (Menlo Park, California) |
| ASSIGNEE(S) | Talis Biomedical Corporation (Menlo Park, California) |
| INVENTOR(S) | Sayeed Andeshmand (Dublin, California); Thomas H. Cauley, III (Redwood City, California); John Dixon (Moss Beach, California); David Glade (San Ramon, California); Hédia Maamar (El Dorado Hills, California); Michael John McAdams (Los Gatos, California); Dzam-Si Jesse Ng (Fremont, California); David Alexander Rolfe (San Francisco, California) |
| ABSTRACT | Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/655007 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/150221 (20130101) A61B 5/150755 (20130101) A61B 5/150961 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820862 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); WASHINGTON UNIVERSITY IN ST. LOUIS (St. Louis, Missouri) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Igor Efimov (Wildwood, Missouri); Sarah Gutbrod (St. Louis, Missouri); Lizhi Xu (Urbana, Illinois); Andrew Bonifas (Woodbury, Minnesota); Richard Chad Webb (Urbana, Illinois); Ahyeon Koh (Champaign, Illinois) |
| ABSTRACT | Provided are devices and methods capable of interfacing with biological tissues, such as organs like the heart, in real-time and using techniques which provide the ability to monitor and control complex physical, chemical, biochemical and thermal properties of the tissues as a function of time. The described devices and methods utilize micro scale sensors and actuators to spatially monitor and control a variety of physical, chemical and biological tissue parameters, such as temperature, pH, spatial position, force, pressure, electrophysiology and to spatially provide a variety of stimuli, such as heat, light, voltage and current. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 14/504736 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/015 (20130101) A61B 5/0036 (20180801) A61B 5/036 (20130101) A61B 5/0084 (20130101) A61B 5/0422 (20130101) A61B 5/0538 (20130101) A61B 5/686 (20130101) A61B 5/1107 (20130101) A61B 5/1116 (20130101) A61B 5/1473 (20130101) A61B 5/02055 (20130101) A61B 5/4836 (20130101) A61B 5/6843 (20130101) A61B 5/6869 (20130101) A61B 5/6885 (20130101) Original (OR) Class A61B 5/14539 (20130101) A61B 5/14546 (20130101) A61B 18/14 (20130101) A61B 2018/00351 (20130101) A61B 2562/028 (20130101) A61B 2562/046 (20130101) A61B 2562/164 (20130101) A61B 2562/0215 (20170801) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/007 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0245 (20130101) A61H 2201/10 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0563 (20130101) A61N 1/0597 (20130101) A61N 1/3621 (20130101) A61N 1/37512 (20170801) A61N 2/002 (20130101) A61N 2/006 (20130101) A61N 5/0603 (20130101) A61N 5/0622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820914 | Pak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Nikita Pak (Allston, Massachusetts); Justin P. Kinney (Quincy, Massachusetts); Edward S. Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method for automated opening of craniotomies includes, under the control of a computer processor, drilling into a skull for a predetermined distance and determining when there is a conductance drop near the drilling tip that indicates skull breakthrough. If the conductance is not below a predetermined threshold, drilling continues iteratively manner until conductance is below the threshold. A craniotomy pattern may be predetermined and automatically drilled under control of the processor. A cranial window may be created by drilling along a path that interpolates between holes to form the circumference of the window. An automated craniotomy opening apparatus includes a drilling apparatus with a drilling tip, at least one drilling apparatus positioning device, a detection device, and a computer processor that controls the drilling apparatus, the positioning device, and the detection device according to the method. Determining conductance may include use of an impedance detection circuit. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/096256 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1695 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/32 (20160201) A61B 90/10 (20160201) A61B 2017/00026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820948 | West et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Karl West (Geneva, Ohio); Jeffrey H. Yanof (Solon, Ohio) |
| ABSTRACT | Holographic image-guidance can be used to track an interventional device during an endovascular percutaneous procedure. The holographic image guidance can be provided by a head-mounted device by transforming tracking data and vasculature image data to a common coordinate system and creating a holographic display relative to a patient's vasculature to track the interventional device during the endovascular percutaneous procedure. The holographic display can also include graphics to provide guidance for the physical interventional device as it travels through the patient's anatomy (e.g., the vasculature). |
| FILED | Friday, October 04, 2019 |
| APPL NO | 16/593374 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/062 (20130101) A61B 5/064 (20130101) A61B 5/745 (20130101) A61B 5/6852 (20130101) A61B 5/7405 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 34/25 (20160201) A61B 90/37 (20160201) A61B 90/361 (20160201) A61B 2034/102 (20160201) A61B 2034/107 (20160201) A61B 2034/2051 (20160201) A61B 2034/2057 (20160201) A61B 2034/2068 (20160201) A61B 2090/363 (20160201) A61B 2090/365 (20160201) A61B 2090/366 (20160201) A61B 2090/367 (20160201) A61B 2090/368 (20160201) A61B 2090/372 (20160201) A61B 2090/502 (20160201) A61B 2090/3762 (20160201) A61B 2090/3983 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 2205/507 (20130101) Optical Elements, Systems, or Apparatus G02B 2027/0174 (20130101) Electric Digital Data Processing G06F 3/012 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00671 (20130101) G06K 9/3216 (20130101) G06K 2009/3225 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 3/0006 (20130101) G06T 3/20 (20130101) G06T 7/344 (20170101) G06T 17/20 (20130101) G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821062 | Clarke et al. |
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| FUNDED BY |
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| APPLICANT(S) | TDELTAS LIMITED (Thame, Oxfordshire, United Kingdom); GOVERNMENT OF THE USA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | TDELTAS LIMITED (Thame, United Kingdom); GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE (Bethesda, Maryland) |
| INVENTOR(S) | Kieran Clarke (Oxford, United Kingdom); Richard Lewis Veech (Rockville, Maryland) |
| ABSTRACT | A method of protecting animal tissue particularly skin, from damage caused by radiation exposure, by contacting the tissue with a ketone ester, a method of protecting skin, reducing the deterioration of skin or maintaining or improving the properties of skin by applying topically to the skin a ketone body comprising (R)-3-hydroxybutyrate moieties is disclosed. A ketone body comprising (R)-3-hydroxybutyrate moieties, especially enantiomerically enriched R-1,3-hydroxybutyl-(R)-3-hydroxybutyrate, for such uses is also provided. |
| FILED | Monday, September 16, 2013 |
| APPL NO | 14/774856 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/86 (20130101) A61K 8/375 (20130101) Original (OR) Class A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 31/22 (20130101) A61K 31/357 (20130101) A61K 47/10 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/00 (20130101) A61Q 17/04 (20130101) A61Q 19/00 (20130101) A61Q 19/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821078 | Scott et al. |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Evan A. Scott (Chicago, Illinois); Sijia Yi (Evanston, Illinois); Sean D. Allen (Chicago, Illinois) |
| ABSTRACT | The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637333 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) Original (OR) Class A61K 47/34 (20130101) A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0086 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/334 (20130101) C08G 65/3342 (20130101) C08G 75/14 (20130101) C08G 2650/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821089 | Snodgrass et al. |
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| FUNDED BY |
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| APPLICANT(S) | VISTAGEN THERAPUETICS, INC. (South San Francisco, California) |
| ASSIGNEE(S) | VISTAGEN THERAPEUTICS, INC. (South San Francisco, California) |
| INVENTOR(S) | H. Ralph Snodgrass (South San Francisco, California); Allen E. Cato (Durham, North Carolina); Jack S. Hicklin (San Diego, California) |
| ABSTRACT | Compositions of L-4-chlorokynurenic are provided, as are methods for the treatment of neurological dysfunction. |
| FILED | Friday, June 08, 2018 |
| APPL NO | 16/003816 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821102 | Castro et al. |
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| APPLICANT(S) | Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Alfredo C. Castro (Winchester, Massachusetts); Michael J. Grogan (Winchester, Massachusetts); Karen J. McGovern (Groton, Massachusetts); Martin R. Tremblay (Melrose, Massachusetts) |
| ABSTRACT | The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/396565 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/17 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/196 (20130101) A61K 31/198 (20130101) A61K 31/454 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/664 (20130101) A61K 31/704 (20130101) A61K 31/4355 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7076 (20130101) A61K 38/21 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 307/94 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 491/04 (20130101) C07D 491/10 (20130101) C07D 491/048 (20130101) C07D 491/107 (20130101) Steroids C07J 69/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821117 | Voskuhl |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Rhonda R. Voskuhl (Los Angeles, California) |
| ABSTRACT | Provided are methods for slowing, halting, and reversing gray matter atrophy and progression of disability in certain neurodegenerative diseases, including multiple sclerosis, using estrogen, alone or in combination with another agent. |
| FILED | Tuesday, September 01, 2015 |
| APPL NO | 15/507863 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/565 (20130101) Original (OR) Class A61K 31/566 (20130101) A61K 49/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821142 | Barber |
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| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | STINGINN, LLC (Miami, Florida) |
| INVENTOR(S) | Glen N. Barber (Miami, Florida) |
| ABSTRACT | The present disclosure provides, in general, a method for selecting a therapy for treating cancer in a human subject and subsequently treating cancer in a subject, which includes isolating a cancer cell from a human subject having cancer, determining the functional activity of the innate immune regulator STimulator of INterferon Genes (STING) or the cellular nucleotidyltransferase, cyclic Guanosine Monophosphate (cGMP)-Adenosine Monophosphate (AMP) Synthase (cyclicGMP-AMP Synthase or cGAS) in the cell, and selecting a therapy for the cancer based on the functional activity of the STING or cGAS in the cell. Also provided, if the functional activity of STING and/or cGAS is determined to be defective in the cell, the therapy selected is one that is effective at killing STING-deficient and/or cGAS-deficient cancer cells, for example a therapy including administering to the subject an oncolytic virus. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/284975 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16633 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/4706 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821143 | Van Den Pol et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Anthony N. Van Den Pol (Branford, Connecticut); Guido Wollmann (Innsbruck, Austria) |
| ABSTRACT | Methods of treating cancer including administering to a subject with cancer a pharmaceutical composition including an effective amount of a chimeric VSV virus are disclosed. The chimeric viruses are based on a VSV background where the VSV G protein is replaced with one or more heterologous viral glycoproteins. In the most preferred embodiment, the VSV G protein is replaced with the glycoprotein from Lassa virus or a functional fragment thereof. The resulting chimeric virus is an oncolytic virus that is attenuated and safe in the brain, yet still retains sufficient oncolytic activity to infect and destroy cancer cells such glioblastoma, and to generate an immune response against infected cancer cells. Methods of using chimeric viruses as a platform for immunization against other pathogenic microbes are also provided. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235425 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 35/12 (20130101) A61K 35/766 (20130101) Original (OR) Class A61K 39/205 (20130101) A61K 45/06 (20130101) A61K 2039/5152 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 7/04 (20130101) C12N 2760/20133 (20130101) C12N 2760/20222 (20130101) C12N 2760/20223 (20130101) C12N 2760/20232 (20130101) C12N 2760/20234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821160 | Lavie et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Arnon Lavie (Chicago, Illinois); Hien-Anh Nguyen (Chicago, Illinois) |
| ABSTRACT | Variant Erwinia chrysanthemi L-asparaginases with reduced L-glutaminase activity and enhanced in vivo circulation are described as are fusion proteins containing an L-asparaginase and three tandem soluble domains of TRAIL for use in the treatment of cancers such as acute lymphoblastic leukemia and acute myeloid leukemia. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 16/080435 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/50 (20130101) Original (OR) Class A61K 47/65 (20170801) A61K 47/67 (20170801) A61K 47/6815 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/52 (20130101) C07K 2319/35 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/82 (20130101) C12N 15/52 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/18 (20130101) Enzymes C12Y 305/01001 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821164 | Hoft et al. |
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| FUNDED BY |
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| APPLICANT(S) | SAINT LOUIS UNIVERSITY (St. Louis, Missouri); EPIVAX, INC. (Providence, Rhode Island) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri); EPIVAX, INC. (Providence, Rhode Island) |
| INVENTOR(S) | Daniel Hoft (St. Louis, Missouri); Chris Eickhoff (St. Louis, Missouri); Annie De Groot (Providence, Rhode Island) |
| ABSTRACT | The present disclosure relates to vaccine formulations and their use in treating and preventing Chagas Disease. |
| FILED | Monday, June 06, 2016 |
| APPL NO | 15/738209 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 38/00 (20130101) A61K 39/00 (20130101) A61K 39/005 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/5154 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/2402 (20130101) Enzymes C12Y 302/01018 (20130101) Technologies for Adaptation to Climate Change Y02A 50/414 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821167 | Hall et al. |
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| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Pamela Hall (Albuquerque, New Mexico); Bryce Chackerian (Albuquerque, New Mexico); David S. Peabody (Albuquerque, New Mexico); Seth Michael Daly (Albuquerque, New Mexico); Bradley Owen Elmore (Worthington, Minnesota); Kathleen Triplett (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is directed to virus-like particles (VLPs) which are engineered to present epitopes from Staphylococcus aureus (SA), preferably autoinducing peptides (AIPs) which regulate quorum-sensing dependent virulence in this pathogen, or epitopes from SA toxins and leukocidins. These VLPs may be used to provide immunogenic compositions and efficacious vaccines. In a mouse model of SA dermonecrosis, vaccination with AIP-containing VLPs or SA toxin-containing VLPs induces protective immunity to limit the pathogenesis of SA infection and promote bacterial clearance. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 16/074886 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2795/18123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821173 | Mond et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | James J. Mond (Silver Spring, Maryland); Clifford M. Snapper (Potomac, Maryland); Xinle Cui (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure provides fusion proteins that incorporate unique mechanisms for multimerizing antigens to enhance their immunogenicity. The fusion proteins comprise at least two antigens, or other vaccine related proteins, separated by a linker sequence and an oligomerization domain. When expressed, the fusion protein forms a muKimeric protein complex, This approach can be used to muHimeri?.e a single antigen/protein or to create multimers comprising two or more different antigens/proteins. Also provided are nucleic acids encoding the fusion proteins. Yet another aspect is directed to methods of inducing or suppressing an immune response in a subject by administering to the subject a vaccine composition comprising a fusion protein or nucleic acid encoding the fusion protein, optionally without using an adjuvant. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971025 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16234 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821177 | Longo |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Valter Longo (Playa del Rey, California) |
| ABSTRACT | This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/273946 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/664 (20130101) A61K 31/704 (20130101) A61K 31/7048 (20130101) A61K 38/31 (20130101) A61K 39/3955 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821178 | Kielian |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| INVENTOR(S) | Tammy Kielian (Omaha, Nebraska) |
| ABSTRACT | Compositions and methods for preventing, ameliorating or treating biofilm infections are provided, including biofilms comprising at least one Pseudomonad or Staphylococcus, such as S. aureus. The biofilm infections may be associated with artificial joints, prostheses or implants. |
| FILED | Tuesday, July 29, 2014 |
| APPL NO | 14/908028 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 38/217 (20130101) A61K 38/1841 (20130101) A61K 38/2066 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 16/18 (20130101) C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 2501/231 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 2333/46 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821186 | Manoharan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arbutus Biopharma Corporation (Burnaby, Canada) |
| ASSIGNEE(S) | ARBUTUS BIOPHARMA CORPORATION (Burnaby, Canada) |
| INVENTOR(S) | Muthiah Manoharan (Cambridge, Massachusetts); Kallanthottathil G. Rajeev (Cambridge, Massachusetts); Muthusamy Jayaraman (Cambridge, Massachusetts); David Butler (Medford, Massachusetts); Jayaprakash K. Nair (Cambridge, Massachusetts); Martin Maier (Cambridge, Massachusetts); Laxman Eltepu (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure wherein R1 and R2 are each independently for each occurrence optionally substituted C10-C30 alkyl, optionally substituted C10-C30 alkenyl, optionally substituted C10-C30 alkynyl, optionally substituted C10-C30 acyl, or -linker-ligand; R3 is H, optionally substituted C1-C10 alkyl, optionally substituted C2-C10 alkenyl, optionally substituted C2-C10 alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, ω-aminoalkyls, ω-(substituted)aminoalkyls, ω-phosphoalkyls, ω-thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; E is O, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(O)2N(Q), S(O)2, N(Q)S(O)2, SS, O═N, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, ω-aminoalkyl, ω-(substituted)aminoalky, ω-phosphoalkyl or ω-thiophosphoalkyl. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123209 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) A61K 47/10 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/28 (20130101) A61K 47/44 (20130101) Original (OR) Class A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) Acyclic or Carbocyclic Compounds C07C 229/08 (20130101) C07C 229/30 (20130101) C07C 237/16 (20130101) C07C 251/38 (20130101) C07C 251/78 (20130101) C07C 271/12 (20130101) C07C 271/20 (20130101) C07C 323/25 (20130101) Heterocyclic Compounds C07D 203/10 (20130101) C07D 317/28 (20130101) C07D 317/44 (20130101) C07D 317/46 (20130101) C07D 317/72 (20130101) C07D 319/06 (20130101) C07D 405/12 (20130101) C07D 491/056 (20130101) C07D 491/113 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) Technologies for Adaptation to Climate Change Y02A 50/464 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821190 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Otto O. Yang (Los Angeles, California); Leonard H. Rome (Tarzana, California); Jan Mrazek (Los Angeles, California) |
| ABSTRACT | Disclosed herein are compositions comprising HIV peptide vaults, which are vault particles comprising complexes of MVP proteins and one or more HIV peptides bound or genetically linked to one or more MVP proteins or packaged within the internal cavities of the vault particles and methods of using thereof. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 16/097248 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/646 (20170801) Original (OR) Class A61K 47/6901 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 14/16 (20130101) C07K 14/47 (20130101) C07K 2319/00 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16022 (20130101) C12N 2740/16122 (20130101) C12N 2740/16222 (20130101) C12N 2740/16322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821195 | Lewis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Jason S. Lewis (New York, New York); Melissa Deri (Hottsville, New York); Lynn Francesconi (Bridgewater, New Jersey); Shashikanth Ponnala (Secaucus, New Jersey) |
| ABSTRACT | Described herein is a chelator for radiolabels (e.g., 89Zr) for targeted PET imaging that is an alternative to DFO. In certain embodiments, the chelator for 89Zr is the ligand, 3,4,3-(LI-1,2-HOPO) (“HOPO”), which exhibits equal or superior stability compared to DFO in chemical and biological assays across a period of several days in vivo. As shown in FIG. 1, the HOPO is an octadentate chelator that stabilizes chelation of radiolabels (e.g., 89Zr). A bifunctional ligand comprising p-SCN-Bn-HOPO is shown in FIG. 4 and FIG. 5. Such a bifunctional ligand can eliminate (e.g., 89Zr) loss from the chelate in vivo and reduce uptake in bone and non-target tissue. Therefore, the bifunctional HOPO ligand can facilitate safer and improved PET imaging with radiolabeled antibodies. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/759154 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class A61K 51/1051 (20130101) A61K 51/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821208 | Desai et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Rajiv Desai (Cambridge, Massachusetts); Neel Satish Joshi (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Sandeep T. Koshy (Boston, Massachusetts); Alexander G. Stafford (Revere, Massachusetts) |
| ABSTRACT | The present disclosure provides click-crosslinked hydrogels and methods of use. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 15/301466 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 27/3886 (20130101) A61L 2300/22 (20130101) A61L 2300/23 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2400/18 (20130101) Heterocyclic Compounds C07D 237/26 (20130101) Peptides C07K 14/78 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821284 | Noble et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Jack Noble (Nashville, Tennessee); Rene H. Gifford (Franklin, Tennessee); Robert F. Labadie (Nashville, Tennessee); Benoit M. Dawant (Nashville, Tennessee) |
| ABSTRACT | Systems and methods for performing current steering compatible image-guided cochlear implant (CI) electrode deactivation. The cochlear implant includes an electrode array having a plurality of electrodes implanted in a cochlea of a living subject. For each electrode, a corresponding distance-vs-frequency (DVF) curve is obtained. An analysis is performed on the DVF curves to identify the interfering electrodes, each having an interference with at least one other electrode. Then, rules may apply to the interfering electrodes in order to select one or more interfering electrodes to be deactivated. The rules may include: keeping the electrode having a corresponding DVF curve located at a left-most location on the plot to avoid a resulting sound frequency upshift; avoiding leaving any electrode stranded without a neighboring electrode; and deactivating a minimal number of the interfering electrodes to ensure that high interference is allowed only for each electrode with one neighboring electrode. |
| FILED | Thursday, October 27, 2016 |
| APPL NO | 15/770260 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/12 (20130101) A61B 5/4848 (20130101) A61B 6/03 (20130101) A61B 6/12 (20130101) A61B 34/20 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/36039 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821285 | Burdick et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); Nicholas A. Terrafranca (Laguna Niguel, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Joel W. Burdick (Pasadena, California); Yanan Sui (Pasadena, California); Yisong Yue (Glendale, California); Nicholas A. Terrafranca (Laguna Niguel, California) |
| ABSTRACT | A system, method, and apparatus for identifying optimal or near optimal complex stimulation waveforms for a neurostimulator device or neuromodulation device are disclosed. An example method includes using a dueling bandits algorithm with correlation among stimulation arms to select a batch of stimulation arms for sequential application to a patient during a therapy session. Each of the stimulation arms specifies complex stimulation waveform parameter values. Feedback from applying the stimulation arms to the patient is recorded and used to update feedback reward values corresponding to at least some of the stimulation arms using a stimulation arm correlation index. A second batch of stimulations arms is selected based upon the updated feedback reward values and applied to a patient. The method is iteratively repeated over a number of therapy sessions until an optimal or near optimal batch of stimulation arms (defining complex stimulation waveforms) is determined. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 16/475856 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36062 (20170801) A61N 1/36117 (20130101) Original (OR) Class A61N 1/36132 (20130101) A61N 1/36157 (20130101) A61N 1/36175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821287 | Michaeli et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Shalom Michaeli (Minneapolis, Minnesota); Silvia Mangia (Minneapolis, Minnesota); Olli Grohn (Kuopio, Finland); Artem Shatillo (Kuopio, Finland); Lauri Lehto (Minneapolis, Minnesota); Matthew Johnson (Minneapolis, Minnesota); Simeng Zhang (Minneapolis, Minnesota); Julia Slopsema (Minneapolis, Minnesota) |
| ABSTRACT | Described here are bioelectric modulation systems and methods for generating rotating or spatially-selective electromagnetic fields. A modulation system includes a multichannel electrode with independently controllable electrode channels that can be operated to generate rotating electromagnetic fields that stimulate cells regardless of their orientation, or to generate spatially-selective electromagnetic fields that preferentially stimulate cells oriented along a particular direction. The bioelectric modulation system may be implemented for stimulation of neurons or other electrically active cells. The bioelectric modulation described here may be used for a variety applications including deep brain stimulation (DBS), spinal cord and vagus nerve stimulation, stimulation of myocardial (heart) tissue, and directional stimulation of muscles. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 15/485544 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36182 (20130101) Original (OR) Class A61N 1/36192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822299 | Chute et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John P. Chute (Sherman Oaks, California); Michael E. Jung (Los Angeles, California); Emelyne Diers (Scotland, United Kingdom) |
| ABSTRACT | The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 16/304427 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Acyclic or Carbocyclic Compounds C07C 205/37 (20130101) C07C 225/16 (20130101) Original (OR) Class C07C 225/22 (20130101) C07C 233/31 (20130101) C07C 311/39 (20130101) C07C 311/44 (20130101) C07C 2601/02 (20170501) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 211/58 (20130101) C07D 231/12 (20130101) C07D 295/205 (20130101) C07D 307/46 (20130101) C07D 307/52 (20130101) C07D 317/66 (20130101) C07D 333/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822301 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Chi-Li Ni (Evanston, Illinois); Jose Juncosa (Salisbury, Maryland) |
| ABSTRACT | Disclosed are cyclopentene compounds for use as inhibitors of gamma-aminobutyric acid (GABA) aminotransferase (AT) and/or ornithine aminotransferase (OAT). The disclosed cyclopentene compounds include 3-carbon substituted 4-aminocyclopent-1-ene-carboxylic acid compounds which may be formulated in pharmaceutical composition for treating diseases and disorders associated with GABA-AT and/or OAT activity, including epilepsy, addiction, and hepatocellular carcinoma (HCC). |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375469 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/30 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 229/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822315 | Pierce et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Joshua G. Pierce (Raleigh, North Carolina); Grant A. Edwards (Raleigh, North Carolina) |
| ABSTRACT | Provided herein are compounds that can exhibit activity as biofilm modulating agents (e.g., activity as biofilm inhibitors and/or activity as biofilm dispersal agents). The compounds can exhibit potent activity against Gram positive biofilms. The compounds can also exhibit activity against Gram negative biofilms. In some cases, the compounds can exhibit both biofilm modulation properties and antimicrobial activity. Compositions comprising these compounds, as well as methods of using thereof, are also described. For example, the compounds described herein can be used in human and animal health (e.g., for the treatment of infection), agriculture, marine coatings, and other coating applications related to prevention of biofilm (e.g., dental, medical, etc.). |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 16/327594 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/76 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 31/08 (20130101) A61L 31/16 (20130101) A61L 2300/204 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 263/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822318 | Carlson et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Erin Elizabeth Carlson (Minneapolis, Minnesota); Shabnam Sharifzadeh (Minneapolis, Minnesota); Alireza Shokri (Minneapolis, Minnesota); Ozden Kocaoglu (Fremont, California); Clayton L. Brown, Jr. (Evansville, Indiana) |
| ABSTRACT | The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, R4, L1, L2 and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful for labeling penicillin-binding proteins (PBPs). |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/988986 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 305/12 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 407/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/573 (20130101) G01N 33/582 (20130101) G01N 2333/948 (20130101) G01N 2415/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822325 | Oprea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico); ROSALIND FRANKLIN UNIVERSITY (North Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tudor I. Oprea (Albuquerque, New Mexico); Cristian George Bologa (Albuquerque, New Mexico); Oleg Ursu (Albuquerque, New Mexico); Jun-Yong Choe (Libertyville, Illinois); Cristina Iancu (Libertyville, Illinois) |
| ABSTRACT | The present invention relates to compounds which have been discovered to be potent ligands (inhibitors) of human GLUT5 (glucose transporter type 5), a facilitative glucose transporter that transports fructose, and their use as ligands assays which can uncover additional ligands of GLUT5, having the potential for being used as drugs. In addition, the present invention is directed to compounds, chemical compositions and methods for treating disease states and conditions which are mediated through GLUT5, including such disease states and conditions as GLUT5 deficiency syndrome, diabetes (type I and II), cancer, metabolic diseases including metabolic syndrome and fatty liver disease, among others. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/735840 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/125 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 317/36 (20130101) Heterocyclic Compounds C07D 317/66 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822340 | Backes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Bradley J. Backes (San Francisco, California); Dustin J. Maly (Seattle, Washington); Scott A. Oakes (San Francisco, California); Feroz R. Papa (San Francisco, California); Gayani Perera (Nugegoda, Sri Lanka); Likun Wang (San Francisco, California) |
| ABSTRACT | Described herein, inter alia, are certain substituted imidazolopyrazines of formula (I) and methods of using the same for modulating the activity of Ire1. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149606 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822353 | Nam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Sangkil Nam (Tujunga, California); David Horne (Altadena, California); Larry Eugene Overman (Corona Del Mar, California); Brad Loertscher (Portage, Michigan) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods of using the same for the treatment of cancer. |
| FILED | Friday, September 15, 2017 |
| APPL NO | 16/333577 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/548 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/12 (20130101) C07D 487/04 (20130101) C07D 513/08 (20130101) C07D 513/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822374 | Walensky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loren D. Walensky (Newton Center, Massachusetts); Federico Bernal (Gaithersburg, Maryland); Geoffrey Wahl (San Diego, California); Mark Wade (Gorizia, Italy) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Salk Institute for Biological Studies (San Diego, California) |
| INVENTOR(S) | Loren D. Walensky (Newton Center, Massachusetts); Federico Bernal (Gaithersburg, Maryland); Geoffrey Wahl (San Diego, California); Mark Wade (Gorizia, Italy) |
| ABSTRACT | Compositions and methods for increasing p53-dependent transcriptional activity in a cell. |
| FILED | Monday, November 14, 2011 |
| APPL NO | 13/884709 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Peptides C07K 4/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822377 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Richard E. Lee (Cordova, Tennessee); Ying Zhao (Memphis, Tennessee); Liu Jiuyu (Collierville, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588738 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/2018 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 38/12 (20130101) A61K 38/12 (20130101) A61K 38/14 (20130101) A61K 38/14 (20130101) A61K 38/15 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 498/14 (20130101) C07D 498/22 (20130101) Peptides C07K 7/06 (20130101) C07K 11/02 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) Y02A 50/471 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822380 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia); AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (Augusta, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Augusta University Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Eileen J. Kennedy (Athens, Georgia); John Cowell (Augusta, Georgia) |
| ABSTRACT | As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/565229 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/18 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822386 | Weiss |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Michael Weiss (Moreland Hills, Ohio) |
| ABSTRACT | A polypeptide comprises an insulin B-chain sequence having the substitutions: Asp at position B10, Ala at position B12, and Glu at position B29, relative to wild type insulin. The polypeptide may additionally comprise a substitution of a halogenated phenylalanine at position B24, such as ortho-fluoro-phenylalanine. Optionally, the polypeptide may additionally comprise a C-terminal dipeptide extension wherein at least one amino acid in the dipeptide contains an acidic side chain, such as Glu-Glu, and/or an N-terminal deletion of one, two or three residues from the B chain. An insulin analogue may comprise any of these polypeptides with an insulin A-chain polypeptide that optionally contains a Glu A8 substitution. The A-chain sequence may be a separate polypeptide or it may be joined to the B-chain polypeptide by a two amino acid linker. The linker may be Trp-Lys or Ala-Lys. The insulin analogue may be used to treat a patient with diabetes mellitus. |
| FILED | Thursday, December 24, 2015 |
| APPL NO | 15/539450 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822387 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Wendell A. Lim (San Francisco, California); Leonardo Morsut (San Francisco, California); Kole T. Roybal (San Francisco, California) |
| ABSTRACT | The present disclosure provides binding-triggered transcriptional switch polypeptides, nucleic acids comprising nucleotide sequences encoding the binding-triggered transcriptional switch polypeptides, and host cells genetically modified with the nucleic acids. The present disclosure also provides chimeric Notch receptor polypeptides, nucleic acids comprising nucleotide sequences encoding the chimeric Notch receptor polypeptides, and host cells transduced and/or genetically modified with the nucleic acids. The present disclosure provides transgenic organisms comprising a nucleic acid encoding a binding triggered transcriptional switch polypeptide and/or a chimeric Notch receptor polypeptide of the present disclosure. Binding triggered transcriptional switch polypeptides and chimeric Notch receptor polypeptides of the present disclosure are useful in a variety of applications, which are also provided. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/831194 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 48/00 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/715 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 19/00 (20130101) C07K 2317/22 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) C07K 2319/60 (20130101) C07K 2319/74 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/566 (20130101) G01N 33/6863 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822407 | Johns |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Roger A. Johns (Reisterstown, Maryland) |
| ABSTRACT | The present invention relates to the field of pulmonary, cardiac and inflammatory disorders. More specifically, the present invention provides methods and compositions for treating disorders associated with Resistin. In a specific embodiment, the present invention provides an antibody that binds human Resistin. |
| FILED | Tuesday, June 17, 2014 |
| APPL NO | 14/899342 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101) A61P 9/10 (20180101) Peptides C07K 14/575 (20130101) C07K 16/26 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/64 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822411 | Leeper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nicholas J. Leeper (Stanford, California); Irving L. Weissman (Stanford, California) |
| ABSTRACT | In the methods of the invention, an agent that increases phagocytosis and/or efferocytosis of cellular components of coronary plaque is administered to the subject in a dose and for a period of time effective to stabilize, prevent or reduce aneurysm disease in the individual. |
| FILED | Wednesday, September 09, 2015 |
| APPL NO | 15/510591 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822419 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Pin Wang (Los Angeles, California); Xiaolu Han (Los Angeles, California); Paul Bryson (Culver City, California) |
| ABSTRACT | The invention is directed to a masked chimeric antigen receptor, comprising: (a) a masking peptide; (b) one or more antigen-specific targeting domains; (c) an extracellular spacer domain; (d) a transmembrane domain; (e) at least one co-stimulatory domain; and (f) an intracellular signaling domain. The mCARs are activated upon cleavage of the masking peptide. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/574743 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/00 (20130101) C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/28 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3038 (20130101) C07K 16/3053 (20130101) C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/70 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/50 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822587 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambrige, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Vijay Kuchroo (Newton, Massachusetts); Hongkun Park (Lexington, Massachusetts); Nir Yosef (Richmond, California); Alexander K. Shalek (Cambridge, Massachusetts); Jellert Gaublomme (Cambridge, Massachusetts); Nicole C. Joller (Brookline, Massachusetts); Chuan Wu (Boston, Massachusetts); Ana Carrizosa Anderson (Brookline, Massachusetts) |
| ABSTRACT | This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications. |
| FILED | Thursday, August 27, 2015 |
| APPL NO | 14/837702 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/37 (20130101) A61K 31/66 (20130101) A61K 31/198 (20130101) A61K 31/661 (20130101) A61K 31/739 (20130101) A61K 31/4745 (20130101) A61K 31/7076 (20130101) A61K 31/7088 (20130101) A61K 33/00 (20130101) A61K 33/06 (20130101) A61K 33/24 (20130101) A61K 38/191 (20130101) A61K 38/363 (20130101) A61K 38/1767 (20130101) A61K 38/1866 (20130101) A61K 38/4866 (20130101) A61K 48/00 (20130101) Peptides C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0637 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) C12N 2501/15 (20130101) C12N 2501/25 (20130101) C12N 2501/90 (20130101) C12N 2501/2301 (20130101) C12N 2501/2306 (20130101) C12N 2501/2323 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 304/21069 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) G01N 2570/00 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822588 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Hua Gu (New York, New York); Richard Hodes (Bethesda, Maryland); Jeffrey J. Chiang (Herndon, Virginia); Ihnkyung Jang (Jupiter, Florida) |
| ABSTRACT | The invention provides an isolated, purified population of human cells comprising CD8+ T cells with reduced Cbl-b activity. The invention provides uses of such cells in methods for inducing or enhancing an anti-tumor immune response in a subject. These methods comprise: (a) providing a cell population, from a subject or from another source, which comprises CD8+ T cells, (b) reducing Cbl-b activity in the CD8+ T-cells, (c) administering the cells of step (b) to the subject. The invention provides methods for making CD8+ T cells that do not require stimulation through a co-receptor in order for the cell to become activated or proliferated in response to contact via its T cell receptor. Such methods are based upon reducing function of Cbl-b. The invention also provides methods for identifying agents which affect Cbl-b expression or activity. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/579583 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/998 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/9015 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70539 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822603 | Marshall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| INVENTOR(S) | Lewis A. Marshall (Oakland, California); Amy L. Hiddessen (Pleasanton, California); Nathan P. Hoverter (Pleasanton, California); Klint A. Rose (Pleasanton, California); Juan G. Santiago (Stanford, California) |
| ABSTRACT | The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/046560 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 2300/0627 (20130101) B01L 2300/0867 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/004 (20130101) B81B 7/0087 (20130101) B81B 2201/05 (20130101) B81B 2201/0278 (20130101) B81B 2203/0338 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/101 (20130101) Original (OR) Class C12N 15/101 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 2565/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44704 (20130101) G01N 27/44739 (20130101) G01N 27/44791 (20130101) G01N 27/44795 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822606 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bo Huang (San Francisco, California); Baohui Chen (San Mateo, California); Lei Qi (Stanford, California); Luke Gilbert (San Francisco, California) |
| ABSTRACT | Methods, compositions, and kits are provided herein for CRISPER/Cas-mediated nucleic acid detection or modification. |
| FILED | Monday, September 29, 2014 |
| APPL NO | 15/025217 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822608 | Erdos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sarepta Therapeutics, Inc. (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); University of Maryland (College Park, Maryland); The Progeria Research Foundation (Peabody, Massachusetts) |
| ASSIGNEE(S) | Sarepta Therapeutics, Inc. (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); University of Maryland (College Park, Maryland); The Progeria Research Foundation (Peabody, Massachusetts) |
| INVENTOR(S) | Michael R. Erdos (Bethesda, Maryland); Francis S. Collins (Bethesda, Maryland); Kan Cao (Bowie, Maryland); Ryszard Kole (Cambridge, Massachusetts); Richard Keith Bestwick (Cambridge, Massachusetts); Leslie B. Gordon (Foxboro, Massachusetts) |
| ABSTRACT | Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/096524 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Peptides C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/323 (20130101) C12N 2310/351 (20130101) C12N 2310/3145 (20130101) C12N 2310/3183 (20130101) C12N 2310/3233 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822618 | Mueller et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Christian Mueller (Worcester, Massachusetts); Florie Borel (Saint Martin, France) |
| ABSTRACT | Transgenic non-human animals, e.g., rodents, e.g., mice comprising genomic mutations that inactive all of the serpin1A genes and thus lack any functional serpinA1 genes. As a result of the genomic mutations, the animals express no hepatic or circulatory AAT protein. Also provided herein are cells and tissues derived from the transgenic mice. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/216324 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) Peptides C07K 14/8125 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/09 (20130101) C12N 15/8509 (20130101) Original (OR) Class C12N 2015/8527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822619 | Ertl et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE WISTAR INSTITUTE (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hildegund C. J. Ertl (Villanova, Pennsylvania); Xiang Yang Zhou (North Wales, Pennsylvania) |
| ABSTRACT | This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of E3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire E3 domain is deleted. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530359 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/015 (20130101) A61K 39/21 (20130101) A61K 39/29 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/861 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/10352 (20130101) C12N 2740/16134 (20130101) C12N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822622 | Luo et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jianhua Luo (Wexford, Pennsylvania); Yanping Yu (Wexford, Pennsylvania); Zhanghui Chen (Hangzhou, China PRC); George Konstantine Michalopoulos (Pittsburgh, Pennsylvania); Joel Nelson (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to methods for treating prostate cancer patients. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-C5orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell that carries the fusion gene. |
| FILED | Monday, March 18, 2019 |
| APPL NO | 16/356587 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 38/1761 (20130101) A61K 48/0058 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1211 (20130101) C12N 15/11 (20130101) C12N 15/63 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/01021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822635 | Akkus et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Ozan Akkus (Cleveland Heights, Ohio); Mikhail Slipchenko (West Lafayette, Indiana); Anna Akkus (Cleveland Heights, Ohio); Shan Yang (Cleveland Heights, Ohio); Bolan Li (Cleveland, Ohio) |
| ABSTRACT | Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111798 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/40 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 21/65 (20130101) G01N 2001/4088 (20130101) G01N 2201/121 (20130101) G01N 2333/928 (20130101) G01N 2333/958 (20130101) G01N 2800/107 (20130101) G01N 2800/345 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822641 | Pourmand et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nader Pourmand (San Mateo, California); Miloslav Karhanek (Santa Cruz, California); Ronald W. Davis (Stanford, California) |
| ABSTRACT | Methods and apparatus for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/967287 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) G01N 27/3276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822652 | Gundlach et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Illumina, Inc. (San Diego, California) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Andrew Laszlo (Seattle, Washington); Ian Derrington (Seattle, Washington); Jeffrey G. Mandell (La Jolla, California) |
| ABSTRACT | The present disclosure provides method and systems for improving nanopore-based analysis of polymers. The disclosure provides methods for selectively modifying one or more monomeric subunit(s) of a kind in a re-analyte polymer that results in a polymer analyte with a modified subunit. The polymer analyte produces a detectable signal in a nanopore-based system. The detectable signal, and/or its deviation from a reference signal, indicates the location of the modified subunit in the polymer analyte and, thus, permits the identification of the subunit at that location in the original pre-analyte polymer. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/029396 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 57/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2523/125 (20130101) C12Q 2523/303 (20130101) C12Q 2525/107 (20130101) C12Q 2525/113 (20130101) C12Q 2525/119 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822655 | Wallace et al. |
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| FUNDED BY |
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| APPLICANT(S) | OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom) |
| ASSIGNEE(S) | OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom) |
| INVENTOR(S) | Mark Wallace (Oxfordshire, United Kingdom); Hagan Bayley (Oxfordshire, United Kingdom); Shuo Huang (Oxford, United Kingdom); Oliver Kieran Castell (Cardiff, United Kingdom); Mercedes Romero-Ruiz (Oxfordshire, United Kingdom) |
| ABSTRACT | The invention relates to a method for detection of analyte interaction with a channel molecule held in a membrane, comprising the optical detection of a modification in the flux of a signal molecule as it passes through the channel molecule by the action of a membrane potential, wherein the modification in the flux is caused by at least partial blockage of the channel molecule by the analyte. The invention further relates to bilayer arrays, components, methods of manufacture and use. |
| FILED | Thursday, July 09, 2015 |
| APPL NO | 15/326109 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/186 (20130101) C12Q 2563/107 (20130101) C12Q 2565/607 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823687 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, Jr. (Lexington, Kentucky) |
| ABSTRACT | A system and method for detecting, measuring, and analyzing for metallic impurities in pharmaceutical drugs and compounds utilizes an x-ray fluorescence system. The system and method may be co-located with a pharmaceutical manufacturing process for in-line continuous monitoring of metal impurities. The pharmaceutical products may be in a form selected from a powder, slurry, pill, tablet, and gel. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/227438 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) Original (OR) Class G01N 33/15 (20130101) G01N 2223/076 (20130101) G01N 2223/652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823736 | Tseng et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Hsian-Rong Tseng (Los Angeles, California); Jiaoti Huang (Los Angeles, California); Edwin M. Posadas (Los Angeles, California); Jiefu Chen (Los Angeles, California); Hao Ho (Los Angeles, California); Zunfu Ke (Los Angeles, California); Ker-Chau Li (Los Angeles, California); Yi-Tsung Lu (Los Angeles, California); Jake Lichterman (Los Angeles, California); Min Song (Los Angeles, California); Leland W. K. Chung (Los Angeles, California) |
| ABSTRACT | A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (CTCs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of CTCs; determining a measured CTC size distribution of the plurality of CTCs based on the measuring; comparing the measured CTC size distribution to a reference CTC size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 15/514438 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 15/1475 (20130101) G01N 33/56966 (20130101) G01N 33/57434 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2015/1006 (20130101) G01N 2015/1488 (20130101) G01N 2015/1493 (20130101) G01N 2015/1497 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823740 | Block et al. |
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| FUNDED BY |
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| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Timothy M. Block (Doylestown, Pennsylvania); Mary Ann Comunale (Bangor, Pennsylvania); Anand Mehta (Lansdale, Pennsylvania) |
| ABSTRACT | Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting lectin binding on proteins in biological fluids, and comparing the detected lectin binding with reference values for the binding of lectin of such proteins in healthy or disease states. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/203616 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 33/57438 (20130101) G01N 2333/4728 (20130101) G01N 2800/08 (20130101) G01N 2800/085 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825353 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Timothy Roberts (Philadelphia, Pennsylvania); David Embick (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods and devices can enhance language processing in an autism spectrum disorder (ASD) individual through auditory manipulation of an auditory stream. The auditory stream is received and includes an acoustic stimulus perceptually representing an object. An acoustic manipulation parameter for a predetermined acoustic detail characteristic is selected. The predetermined acoustic detail characteristic is associated with the ASD individual and is based on a measured language processing capability of the ASD individual. The auditory stream is modified based on the selected parameter, to reduce the predetermined acoustic detail characteristic while preserving a lexicality of the stimulus, such that the reduced acoustic detail characteristic enhances perception of the object by the ASD individual even when the stimulus includes two or more acoustically distinct stimuli each perceptually representing the object. The modified auditory stream is output to the ASD individual via at least one loudspeaker. |
| FILED | Wednesday, August 13, 2014 |
| APPL NO | 14/910922 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/168 (20130101) A61B 5/4803 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/04 (20130101) G09B 19/00 (20130101) Original (OR) Class G09B 19/04 (20130101) G09B 23/28 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/00 (20130101) G10L 13/02 (20130101) G10L 15/26 (20130101) G10L 21/003 (20130101) G10L 21/0364 (20130101) G10L 2021/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10820617 | O'Hara et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reginald B O'Hara (Beavercreek, Ohio); Paul Falcone (West Des Moines, Iowa) |
| ABSTRACT | A water-soluble, meal-replacement performance powder comprising essential vitamins, minerals, and nutrients per United States Department of Agriculture (USDA) 100% recommended daily intake (RDI) guidelines, plus amino acids, electrolytes, hydrolyzed protein, natural caffeine, theacrine, L-leucine, amylopectin/chromium complex, and a bacterial stat. Based on a 2000 kilocalorie diet (all weights approximate), essential vitamins include vitamin A (5000 IU), vitamin B6 (2 mg), vitamin B12 (6 mcg), vitamin C (500 mg), vitamin D (400 IU), vitamin E (30 IU), vitamin K (80 mcg), biotin (300 mcg), folate (400 mcg), niacin (20 mg), pantothenic acid (10 mg), riboflavin (1.7 mcg), and thiamine (1.5 mcg); essential minerals include calcium (500 mg), chromium (120 mcg), copper (2 mg), iodine (150 mcg), magnesium (200 mg), manganese (2 mg), molybdenum (75 mcg), potassium (1500 mg), sodium (1730 mg), and zinc (15 mg); and essential nutrients include protein (40 g). A single serving package includes about 430 kilocalories. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/939397 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/16 (20160801) A23L 33/18 (20160801) A23L 33/125 (20160801) A23L 33/155 (20160801) Original (OR) Class A23L 33/175 (20160801) Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 10/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820655 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Armand F. Lewis (Mattapoisett, Massachusetts); Yong K. Kim (North Dartmouth, Massachusetts) |
| ABSTRACT | A flocked helmet cover pad (FHCP) attachable add-on to a helmet cover includes a central hub and multiple appendages attached to the central hub. The appendages are shaped and arranged to provide additional impact energy absorption properties for a helmet. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/706962 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Hats; Head Coverings A42B 3/061 (20130101) Original (OR) Class A42B 3/063 (20130101) A42B 3/069 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 71/10 (20130101) A63B 2209/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/245 (20130101) B32B 2307/56 (20130101) B32B 2307/554 (20130101) B32B 2437/04 (20130101) Wall, Floor, or Like Covering Materials, e.g Linoleum, Oilcloth, Artificial Leather, Roofing Felt, Consisting of a Fibrous Web Coated With a Layer of Macromolecular Material; Flexible Sheet Material Not Otherwise Provided for D06N 7/0097 (20130101) D06N 2203/068 (20130101) D06N 2209/103 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/04 (20130101) F41H 1/08 (20130101) F41H 5/0471 (20130101) F41H 5/0478 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820847 | Andeshmand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Talis Biomedical Corporation (Menlo Park, California) |
| ASSIGNEE(S) | Talis Biomedical Corporation (Menlo Park, California) |
| INVENTOR(S) | Sayeed Andeshmand (Dublin, California); Thomas H. Cauley, III (Redwood City, California); John Dixon (Moss Beach, California); David Glade (San Ramon, California); Hédia Maamar (El Dorado Hills, California); Michael John McAdams (Los Gatos, California); Dzam-Si Jesse Ng (Fremont, California); David Alexander Rolfe (San Francisco, California) |
| ABSTRACT | Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/655007 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/150221 (20130101) A61B 5/150755 (20130101) A61B 5/150961 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820850 | Publicover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Google LLC (Mountain View, California) |
| ASSIGNEE(S) | Google LLC (Mountain View, California) |
| INVENTOR(S) | Nelson G. Publicover (Reno, Nevada); William C. Torch (Reno, Nevada) |
| ABSTRACT | Systems and methods are provided to measure reaction times and/or responses for head, eye, eyelid movements, and/or changes in pupil geometry. The system includes eyewear or headwear including one or more eye-tracking cameras for monitoring the position and geometry of at least one eye and its components of the user, one or more scene cameras for monitoring the user's surroundings, and one or more processors to determine reaction times. Optionally, the system may include one or more of a multi-axis accelerometer to monitor head movements, light sources to trigger visual evoked responses, and/or electronic inputs that may be used to indicate the time of occurrence of external reference events. Measured reaction times and other measurements may be monitored for use in a range of applications. Responses and reaction times may be measured continuously over extended periods, even over a lifetime to measure consequences of the aging process. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897580 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/112 (20130101) A61B 3/113 (20130101) A61B 5/162 (20130101) Original (OR) Class A61B 5/1103 (20130101) A61B 5/1114 (20130101) A61B 5/6803 (20130101) A61B 2560/0242 (20130101) A61B 2562/0204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820888 | Boser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bernhard E. Boser (Berkeley, California); David A. Horsley (Albany, California); Hao-Yen Tang (Berkeley, California); Yipeng Lu (Davis, California) |
| ABSTRACT | An ultrasonic imaging apparatus having a Micro-machined Ultrasonic Transducer (MUT), such as a Piezoelectric MUT (PMUT) or Capacitive MUT (CMUT), with a transmitting mode and a receiving mode for generating and sensing acoustic pressure in imaging applications. During transmission in a PMUT the inverse piezoelectric effect on the piezo layer causes transverse stress, which causes a bending moment in the PMUT structure leading to out-of-plane deflection. Different applied signs of voltage generates different signs of stress inside the piezo that in turn cause oscillating motion generating an acoustic pressure wave. During signal reception, incident pressure waves deflect the PMUT creating transverse stress, resulting in a charge determined through measuring voltage between electrodes. The apparatus is particularly well-suited for use in health care, such as measuring fat/muscle thickness, blood-flow, and blood pressure. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/065621 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/04 (20130101) A61B 8/06 (20130101) A61B 8/4483 (20130101) Original (OR) Class A61B 8/5207 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821173 | Mond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | James J. Mond (Silver Spring, Maryland); Clifford M. Snapper (Potomac, Maryland); Xinle Cui (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure provides fusion proteins that incorporate unique mechanisms for multimerizing antigens to enhance their immunogenicity. The fusion proteins comprise at least two antigens, or other vaccine related proteins, separated by a linker sequence and an oligomerization domain. When expressed, the fusion protein forms a muKimeric protein complex, This approach can be used to muHimeri?.e a single antigen/protein or to create multimers comprising two or more different antigens/proteins. Also provided are nucleic acids encoding the fusion proteins. Yet another aspect is directed to methods of inducing or suppressing an immune response in a subject by administering to the subject a vaccine composition comprising a fusion protein or nucleic acid encoding the fusion protein, optionally without using an adjuvant. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971025 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16234 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821208 | Desai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Rajiv Desai (Cambridge, Massachusetts); Neel Satish Joshi (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Sandeep T. Koshy (Boston, Massachusetts); Alexander G. Stafford (Revere, Massachusetts) |
| ABSTRACT | The present disclosure provides click-crosslinked hydrogels and methods of use. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 15/301466 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 27/3886 (20130101) A61L 2300/22 (20130101) A61L 2300/23 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2400/18 (20130101) Heterocyclic Compounds C07D 237/26 (20130101) Peptides C07K 14/78 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821211 | Van Dyke |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Mark E. Van Dyke (Winston-Salem, North Carolina) |
| ABSTRACT | Methods are provided to produce optimal fractionations of charged keratins that have superior biomedical activity. Also provided are medical implants coated with these keratin preparations. Further provided are methods of treating blood coagulation in a patient in need thereof. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/227556 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1748 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/32 (20130101) A61L 26/0047 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/227 (20130101) A61L 29/16 (20130101) A61L 29/048 (20130101) A61L 29/048 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 31/047 (20130101) A61L 33/0041 (20130101) A61L 33/128 (20130101) Original (OR) Class A61L 2300/42 (20130101) A61L 2300/424 (20130101) Peptides C07K 1/36 (20130101) C07K 14/4741 (20130101) Compositions of Macromolecular Compounds C08L 89/04 (20130101) C08L 89/04 (20130101) C08L 89/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821445 | Selden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts) |
| ABSTRACT | A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator intervention includes microfluidic and macrofluidic features that are acted on by instrument subsystems in a series of scripted processing steps. Methods for fabricating these complex biochips of high feature density by injection molding are also provided. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/144245 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 69/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/142 (20130101) B01L 2300/18 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0819 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/1822 (20130101) B01L 2400/0421 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) B01L 2400/0677 (20130101) B01L 2400/0688 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0025 (20130101) B29C 2045/0027 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2105/251 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) G01N 27/44704 (20130101) G01N 27/44743 (20130101) G01N 27/44791 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4998 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821709 | Dimitrakopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); Universidade Federal do Rio Grande do Sul-UFRGS (Porto Alegre, Brazil); The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); Universidade Federal Do Rio Grande Do Sul-UFRGS (Porto Alegre, Brazil); The Government of the United States of America, As Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christos Dimitrakopoulos (Suffield, Connecticut); Dimitrios Maroudas (Amherst, Massachusetts); Andre R. Muniz (Porto Alegre, Brazil); David Kurt Gaskill (Alexandria, Virginia) |
| ABSTRACT | An article of manufacture includes a first graphene layer, a second graphene layer over the first graphene layer, the second graphene layer oriented at a first interlayer twist angle with respect to the first graphene layer and bonded by interlayer covalent bonds to the first graphene layer, and a third graphene layer over the second graphene layer, the third graphene layer oriented at a second interlayer twist angle with respect to the second graphene layer and bonded by interlayer covalent bonds to the second graphene layer. A multi-layer graphene article includes at least three graphene layers, each graphene layer being oriented at an interlayer twist angle with respect to an adjacent graphene layer and bonded by interlayer covalent bonds to the adjacent graphene layer. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/790524 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 18/00 (20130101) Original (OR) Class B32B 37/025 (20130101) B32B 38/10 (20130101) B32B 2264/108 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/182 (20170801) C01B 32/186 (20170801) C01B 32/194 (20170801) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822066 | Reynoso |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bryan Reynoso (Ponte Vedra Beach, Florida) |
| ABSTRACT | An automatic depth regulation system uses changes in water pressure to automatically control the depth of an underwater vehicle. The system uses a piston chamber having a piston that is movably disposed within the chamber and mechanically linked to the vehicle's fins. The bottom of the piston is subjected to pressure from the ambient environment through which the vehicle travels. The chamber contains a compressible medium at a preselected pressure above the piston. A spring is also above the piston in the chamber. Changes in ambient pressure on the bottom of the piston causes the piston to move within the chamber, thereby rotating the fins to adjust the depth of the vehicle to the desired, preselected, depth. The desired depth is determined by the pressure and spring force exerted on the top of the piston in opposition to the ambient pressure. |
| FILED | Wednesday, July 24, 2019 |
| APPL NO | 16/521011 |
| ART UNIT | 3617 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/22 (20130101) B63G 8/24 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822110 | Colby |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Steven D. Colby (Owego, New York) |
| ABSTRACT | Some embodiments include a countermeasure assistance system that, in response to detecting a threat to an aircraft, calculates and presents via a user interface an instruction to assist a pilot in evading the threat. For example, the system may determine a direction to which the aircraft should be turned to present a beam of the aircraft toward the threat, which may assist in evading a radar-enabled threat. The system may calculate a shortest turn to present the beam to the threat. The system may additionally display information regarding a position, nature, and degree of the threat, including through formatting of at least a portion of a user interface for displaying information regarding the threat. The system may additionally calculate and display an intervisibility zone for the threat and for the aircraft's current position to further assist the pilot in navigating to an area at which the threat may be evaded. |
| FILED | Thursday, September 08, 2016 |
| APPL NO | 15/259805 |
| ART UNIT | 2142 — Graphical User Interface and Document Processing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/12 (20130101) G01S 7/021 (20130101) G01S 7/24 (20130101) Traffic Control Systems G08G 5/006 (20130101) G08G 5/0017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822245 | Gross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Adam F. Gross (Santa Monica, California); Shanying Cui (Calabasas, California); John J. Vajo (West Hills, California); Christopher S. Roper (Santa Monica, California) |
| ABSTRACT | Methods to fabricate tightly packed arrays of nanoparticles are disclosed, without relying on organic ligands or a substrate. In some variations, a method of assembling particles into an array comprises dispersing particles in a liquid solution; introducing a triggerable pH-control substance capable of generating an acid or a base; and triggering the pH-control substance to generate an acid or a base within the liquid solution, thereby titrating the pH. During pH titration, the particle-surface charge magnitude is reduced, causing the particles to assemble into a particle array. Other variations provide a device for assembling particles into particle arrays, comprising a droplet-generating microfluidic region; a first-fluid inlet port; a second-fluid inlet port; a reaction microfluidic region, disposed in fluid communication with the droplet-generating microfluidic region; and a trigger source configured to trigger generation of an acid or a base from at least one pH-control substance contained within the reaction microfluidic region. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/155129 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0075 (20130101) B01J 2219/00331 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) B01J 2219/00686 (20130101) B01J 2219/00754 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/0647 (20130101) B01L 2200/0673 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/265 (20200101) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/02 (20130101) C01G 49/0045 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/16 (20130101) C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/10 (20130101) C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/22 (20130101) C30B 29/62 (20130101) C30B 33/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822262 | Gibson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel J. Gibson (Cheverly, Maryland); Rafael R. Gattass (Washington, District of Columbia); Daniel L. Rhonehouse (Chesapeake Beach, Maryland); Shyam S. Bayya (Ashburn, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | An optical fiber with multiple openings made from the steps comprising fabricating an extrusion die using at least one additive manufacturing technique such that the extrusion die has a first set of plurality of channels that combine inside the die into a second set of plurality of channels with a different set of shapes and sizes, extruding a glass through the extrusion die, forming a fiber optic preform having a plurality of longitudinal openings that run the entire length of the fiber optic preform, attaching a barrier layer to the fiber optic preform to form a series of channels to which pressure can be applied by a gas, wherein each channel has a pressure that is independently controlled, and stretching the fiber optic preform at an elevated temperature into an optical fiber with multiple openings. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/430254 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/09 (20190201) B29C 48/11 (20190201) B29C 48/0018 (20190201) B29C 48/30 (20190201) B29C 48/32 (20190201) B29C 48/345 (20190201) B29C 48/3003 (20190201) Manufacture, Shaping, or Supplementary Processes C03B 17/04 (20130101) Original (OR) Class C03B 37/0279 (20130101) C03B 2201/86 (20130101) C03B 2201/88 (20130101) C03B 2203/42 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02042 (20130101) G02B 6/02366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822466 | Leventis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aerogel Technologies, LLC (Glendale, Wisconsin) |
| ASSIGNEE(S) | Aerogel Technologies, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Nicholas Leventis (Rolla, Missouri); Chariklia Sotiriou-Leventis (Rolla, Missouri); Chakkaravarthy Chidambareswarapattar (Rolla, Missouri) |
| ABSTRACT | Nanoporous three-dimensional networks of polyurethane particles, e.g., polyurethane aerogels, and methods of preparation are presented herein. Such nanoporous networks may include polyurethane particles made up of linked polyisocyanate and polyol monomers. In some cases, greater than about 95% of the linkages between the polyisocyanate monomers and the polyol monomers are urethane linkages. To prepare such networks, a mixture including polyisocyanate monomers (e.g., diisocyanates, triisocyanates), polyol monomers (diols, triols), and a solvent is provided. The polyisocyanate and polyol monomers may be aliphatic or aromatic. A polyurethane catalyst is added to the mixture causing formation of linkages between the polyisocyanate monomers and the polyol monomers. Phase separation of particles from the reaction medium can be controlled to enable formation of polyurethane networks with desirable nanomorphologies, specific surface area, and mechanical properties. Various properties of such networks of polyurethane particles (e.g., strength, stiffness, flexibility, thermal conductivity) may be tailored depending on which monomers are provided in the reaction. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/220091 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/267 (20130101) B01J 20/3078 (20130101) B01J 20/28011 (20130101) B01J 20/28042 (20130101) B01J 20/28047 (20130101) B01J 20/28057 (20130101) B01J 20/28078 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) C01B 32/05 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/06 (20130101) C08G 18/792 (20130101) C08G 18/3215 (20130101) C08G 18/3872 (20130101) C08G 18/7657 (20130101) C08G 18/7664 (20130101) C08G 18/7893 (20130101) C08G 2101/0091 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/286 (20130101) Original (OR) Class C08J 2201/04 (20130101) C08J 2201/0502 (20130101) C08J 2205/026 (20130101) C08J 2205/042 (20130101) C08J 2375/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/21 (20150115) Y10T 428/1376 (20150115) Y10T 428/2982 (20150115) Y10T 428/24149 (20150115) Y10T 428/31547 (20150401) Y10T 428/249953 (20150401) Y10T 428/249978 (20150401) Y10T 428/249986 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822952 | Beattie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jeffrey S. Beattie (South Glastonbury, Connecticut); Jason D. Himes (Tolland, Connecticut); Matthew Andrew Hough (West Hartford, Connecticut); Christopher Corcoran (Manchester, Connecticut) |
| ABSTRACT | An assembly according to an exemplary aspect of the present disclosure includes, among other things, a disk, a cover plate providing a cavity at a first axial side of the disk, a passageway including an inlet provided by a notch in at least one of the disk and the cover plate in fluid communication with the cavity, and the passageway extending from the inlet to an exit provided at a second axial side of the disk opposite the first axial side, the exit in fluid communication with the inlet, and the passageway configured to provide fluid flow from the cavity to the exit. |
| FILED | Wednesday, September 17, 2014 |
| APPL NO | 15/021060 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/12 (20130101) F01D 5/081 (20130101) Original (OR) Class F01D 5/082 (20130101) F01D 5/085 (20130101) F01D 5/187 (20130101) F01D 5/3007 (20130101) F01D 5/3015 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/81 (20130101) F05D 2260/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822953 | McCaffrey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael G. McCaffrey (Windsor, Connecticut); Elizabeth F. Vinson (Broad Brook, Connecticut) |
| ABSTRACT | A gas turbine engine includes a compressor section, a combustor fluidly connected to the compressor section, and a turbine section fluidly connected to the combustor and mechanically connected to the compressor section via a shaft. Multiple rotors are disposed in one of the compressor section and the turbine section. Each of the rotors includes a rotor disk portion having a radially inward bore, and is static relative to the shaft. Each rotor is axially adjacent at least one other rotor and a gap is defined between each rotor and an adjacent rotor. A cooling passage for a cooling flow is defined between the shaft and the rotors, and a cooling flow redirection component is disposed at the gap and is operable to redirect the cooling flow in the cooling passage into the gap. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/800544 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/082 (20130101) Original (OR) Class F01D 5/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822964 | McCaffrey |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael G. McCaffrey (Windsor, Connecticut) |
| ABSTRACT | A blade outer air seal (BOAS) for a gas turbine engine includes a seal ring body having a radially inner face and a radially outer face that axially extend between a leading edge portion and a trailing edge portion and a segmented spline that extends from the radially outer face of the seal ring body, the seal secured to the radially inner face of the seal ring body. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189233 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) Original (OR) Class F01D 9/04 (20130101) F01D 9/048 (20130101) F01D 11/08 (20130101) F01D 11/18 (20130101) F01D 25/26 (20130101) F01D 25/243 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/24 (20130101) F05D 2240/30 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822981 | Sener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Alexander Martin Sener (Cincinnati, Ohio); Brian David Keith (Cincinnati, Ohio); David Alan Frey (West Chester, Ohio); Jamil Darnell Grant (Maineville, Ohio) |
| ABSTRACT | A variable guide vane assembly is provided for a turbine defining a core air flowpath. The variable guide vane assembly includes an airfoil band defining a flowpath surface and a cavity. The variable guide vane assembly further includes an airfoil including a first end extending at least partially into the cavity of the airfoil band and an opposite second end, the airfoil extending generally along an axis between the first end and the second end and being moveable generally about the axis relative to the airfoil band. The variable guide vane assembly further includes a sealing element operable to form a seal between the first end of the airfoil and the airfoil band. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 15/796942 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) F01D 11/003 (20130101) F01D 11/005 (20130101) Original (OR) Class F01D 17/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 9/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/3213 (20130101) F05D 2240/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822990 | Davis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Timothy M. Davis (Kennebunk, Maine); Brian Duguay (Berwick, Maine) |
| ABSTRACT | An active clearance control system of a gas turbine engine includes a multiple of blade outer air seal assemblies and a multiple of rotary ramps. Each of the multiple of rotary ramps is associated with one of the multiple of blade outer air seal assemblies. A method of active blade tip clearance control for a gas turbine engine is provided. The method includes rotating a multiple of rotary ramps to control a continuously adjustable radial position for each of a respective multiple of blade outer air seal assemblies. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399254 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822996 | Dowdell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Charles William Dowdell (Ipswich, Massachusetts); Jacques Paul (Somerville, Massachusetts); Paul J. Morrison (Piedmont, California) |
| ABSTRACT | A method for determining an engine heath of an aircraft engine includes determining, by one or more control devices, the aircraft engine is operating in a bleed off condition; determining, by the one or more control devices, a first engine health modifier value while the aircraft engine is operating in the bleed off condition, the first of engine health modifier value including a compressor leakage flow value; determining, by the one or more control devices, a second plurality of engine health modifier values while the aircraft engine is operating in a bleed on condition; and determining, by the one or more control devices, an engine health parameter using at least one of the second plurality of engine health modifier values determined while the aircraft engine is operating in the bleed on condition and the compressor leakage flow value determined while the aircraft engine was operating in the bleed off condition. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/918266 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) B64D 2045/0085 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/80 (20130101) F05D 2260/81 (20130101) F05D 2260/83 (20130101) F05D 2270/311 (20130101) F05D 2270/312 (20130101) F05D 2270/313 (20130101) F05D 2270/3011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823087 | DeFelice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); Peter J. Dowd (Granby, Connecticut) |
| ABSTRACT | An inline valve includes a valve body, a valve member, and a control manifold. The valve body has an exterior, an inlet, and an outlet. The valve member is supported within the valve body and is movable between a first position and a second position. The inlet in fluid communication with the outlet while the valve member is in the first position and the inlet fluidly separated from the outlet while the valve member is in the second position. The control manifold is supported by the valve body, has a reference fluid port and a control fluid port, and is in pneumatic communication with the valve member through the valve body exterior to passive movement of the valve member according to pressure at the valve body inlet. Gas turbine engines and methods of controlling valves are described. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447780 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/18 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/126 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) Y10T 137/3421 (20150401) Y10T 137/3476 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823199 | Jones |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Scott Allen Jones (Durham, North Carolina) |
| ABSTRACT | Coating systems for components of a gas turbine engine, such as a compressor case, are provided. The coating system can include a dense layer disposed along the inner surface of the compressor case as well as an abradable, top coat disposed along the dense layer. The combination of dense layer and abradable top coat can reduce the occurrence of galvanic corrosion of the coating system and thereby increase the lifetime of the coating system and preserve blade clearances within the compressor. Methods are also provided for applying the coating system onto a compressor case. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493719 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/122 (20130101) F01D 25/24 (20130101) Non-positive-displacement Pumps F04D 29/023 (20130101) F04D 29/526 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2230/90 (20130101) F05D 2230/312 (20130101) F05D 2260/95 (20130101) F05D 2300/173 (20130101) F05D 2300/522 (20130101) F05D 2300/611 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823308 | DeFelice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); Peter J. Dowd (Granby, Connecticut) |
| ABSTRACT | A controller for an inline valve includes a manifold seating a set screw and has a reference fluid port, a control fluid port, and an actuator fluid port. A selector is movable within the manifold between a first position and a second position, the reference fluid port in fluid communication with the actuator fluid port in the first position, the control fluid port in fluid communication with the actuator fluid port in the second position. A biasing member is arranged between the selector and the set screw and urges the selector towards the first position. The set screw extends through an exterior of the manifold for adjustment of differential in pressures at the reference fluid port and the control fluid port responsive to which the selector moves between the first position and the second position. Inline valves and methods of controlling fluid flow through inline valves are also described. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447784 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/50 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 7/0133 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) Y10T 137/3421 (20150401) Y10T 137/3476 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823412 | Quach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | San Quach (Southington, Connecticut); Andreas Sadil (Newington, Connecticut); Donald W. Peters (Colchester, Connecticut) |
| ABSTRACT | A coated panel for a gas turbine engine includes a panel having a panel inner surface and a pocket formed in the panel inner surface, the pocket having a pocket depth. A coating is applied to the pocket such that a coating edge is disposed within the pocket to enhance coating retention to the panel. A gas turbine engine includes a turbine, a combustor to supply hot combustion gases to the turbine along a gas path, and one or more coated panels located along the gas path. The one or more panels includes a panel having a panel inner surface, and a pocket formed in the panel inner surface, the pocket having a pocket depth. A coating is applied to the pocket such that a coating edge is located within the pocket to enhance coating retention to the panel. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477518 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 2/006 (20130101) C23C 4/02 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/145 (20130101) Jet-propulsion Plants F02K 1/822 (20130101) F02K 9/974 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/90 (20130101) F05D 2300/611 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 2900/00018 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) Y02T 50/6765 (20180501) Technical Subjects Covered by Former US Classification Y10T 428/2462 (20150115) Y10T 428/24537 (20150115) Y10T 428/24545 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823415 | Riley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Kristy Rose Riley (Vernon, Connecticut); John R. Battye (Lebanon, Connecticut); Joanne V. Rampersad (Manchester, Connecticut); San Quach (Southington, Connecticut) |
| ABSTRACT | A deflector panel for a combustor of a gas turbine engine includes an outer radial edge, an inner radial edge, and two circumferential edges extending between the outer radial edge and the inner radial edge. Each circumferential edge including a panel scallop at least partially defining a deflector opening receptive of a fuel nozzle of the combustor. A combustor of a gas turbine engine includes a combustor shell at least partially defining a combustion zone therein, and a deflector assembly operably connected to the combustor shell. The deflector assembly includes a plurality of circumferentially abutted deflector panels. Each deflector panel includes an outer radial edge, an inner radial edge, and two circumferential edges extending between the outer radial edge and the inner radial edge. Each circumferential edge includes a panel scallop at least partially defining a deflector opening. A fuel nozzle extends through the deflector opening. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995508 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/35 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823418 | Zelina et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Joseph Zelina (Waynesville, Ohio); Sarah Marie Monahan (Latham, New York); Michael Anthony Benjamin (Cincinnati, Ohio); Venkat Eswarlu Tangirala (Niskyuna, New York); Sibtosh Pal (Mason, Ohio); William Thomas Ross (Renton, Washington) |
| ABSTRACT | A combustor for a turbine engine includes an inner combustion liner and an outer combustion liner together defining at least in part an interior. The interior includes a combustion chamber and a main portion. The combustor also includes an inlet combustion liner at least partially defining the combustion chamber of the interior and including an inlet assembly. The inlet assembly includes at least two cavity air tubes arranged along the axial direction, each cavity air tube extending between an inlet and an outlet, the outlet of each cavity air tube in airflow communication with the combustion chamber for providing the combustion chamber with a flow of air. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 15/447847 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) Original (OR) Class F23R 3/42 (20130101) F23R 3/045 (20130101) F23R 3/50 (20130101) F23R 3/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823422 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Arthur Wesley Johnson (Cincinnati, Ohio); Joseph Zelina (Waynesville, Ohio); Eric John Stevens (Mason, Ohio); Clayton Stuart Cooper (Loveland, Ohio); Beverly Stephenson Duncan (West Chester, Ohio); Juntao Zhang (Mason, Ohio) |
| ABSTRACT | A trapped vortex combustor for use in a gas turbine engine defines a radial direction, an axial direction, and a circumferential direction. The trapped vortex combustor includes an outer vortex chamber wall defining a forward end, and a dome attached to, or formed integrally with, the outer vortex chamber wall at the forward end of the outer vortex chamber wall. The dome and outer vortex chamber wall define at least in part a combustion chamber having an outer trapped vortex chamber. The dome includes an air chute defining an airflow direction. The radial direction and axial direction of the trapped vortex combustor define a reference plane extending through the air chute, the airflow direction of the air chute defining an angle greater than zero with the reference plane. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/785726 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/35 (20130101) F05D 2240/36 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/04 (20130101) F23R 3/12 (20130101) F23R 3/14 (20130101) F23R 3/18 (20130101) F23R 3/50 (20130101) F23R 3/58 (20130101) Original (OR) Class F23R 2900/00015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823478 | Williams |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin S. Williams (Wrentham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin S. Williams (Wrentham, Massachusetts) |
| ABSTRACT | A modular cooling/heating device includes a thermal plant such as a micro-refrigeration system with an integrated heater for providing remote, on-site cooling/heating to an insulated enclosure defining a modular cooling volume by exchanging a liquid thermal-transfer medium, such as available tap water or alcohol-glycol mixture, with a thermal exchanger disposed within the insulated enclosure. A thermal source adapted for thermal exchange with a fluidic transfer medium combined with an engageable fluidic coupling between the thermal source and the thermal exchanger provides for detachable engagement of the thermal exchanger in a verity of contexts. The thermal exchange may take the form of a flexible, fluid carrying pouch, or a rigid thermal vessel having substantial vacuum and phase-change lining features for thermal inertia. Both may be combined with an integrated, insulated enclosure including the battery and thermal source as a combined, portable package. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/599726 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/08 (20130101) F25D 11/006 (20130101) Original (OR) Class F25D 17/02 (20130101) F25D 2201/14 (20130101) F25D 2331/803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823512 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Fanghao Yang (Somerset, New Jersey) |
| ABSTRACT | A cold plate structure in a two-phase cooling system is provided. The cold plate, where the cold plate structure has at least one microchannel with a cross-sectional area along a radial direction, wherein the cross-sectional area expands in a first direction that is substantially tangential to the radial direction and expands in a second direction that is substantially tangential to the radial direction and substantially tangential to the first direction. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123550 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/0093 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 23/473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823571 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Jianfeng Wu (Tucson, Arizona); Karl D. Nelson (Plymouth, Minnesota); Matthew Wade Puckett (Scottsdale, Arizona) |
| ABSTRACT | A ring-laser gyroscope which generates in an optical ring resonator and in response to a first pump beam, a first back-scattered beam propagating in a direction; generates in the optical ring resonator and in response to a second pumped beam, a second back-scattered beam propagating in an opposite direction; determines a first difference between the frequencies of the first and second back-scattered beams; reverses the directions of the first and second back-scattered beams; determines a second difference between the frequencies of the first and second back-scattered beams; determines a third difference between the first and second differences; and determines a rotation of the optical ring resonator in response to the third difference. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527989 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/70 (20130101) Original (OR) Class G01C 19/665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823607 | Whitaker |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | George W Whitaker (Albuquerque, New Mexico) |
| ABSTRACT | An electromagnetic (EM) energy conversion and measurement system and related methods are provided for converting a first EM energy (e.g., infrared) to a second EM energy (e.g., visible light) having at least a different wavelength or frequency than the first EM energy then using a detector to detect or measure the second EM energy. An array of conversion and detector assemblies each include a first section and a second section. Exemplary first sections can include at least one optical grade substrate formed with a first material (e.g., germanium) having a first index of refraction that refracts a first EM energy so as to change a frequency and propagation time of the first EM energy to produce a second EM energy. Exemplary second sections include an EM energy detector having an index of refraction that is the same as the first material. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/816062 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/0407 (20130101) Original (OR) Class G01J 1/1626 (20130101) G01J 1/4228 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823667 | Ramachandran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Gautam Prabhakar (Boston, Massachusetts); Aaron G. Peterson-Greenberg (Cambridge, Massachusetts) |
| ABSTRACT | A system comprises an electromagnetic radiation source, a polarizing element, a mode converter, an optical fiber, and a measurement device. The polarizing element receives electromagnetic radiation produced by the electromagnetic radiation source and outputs linearly-polarized electromagnetic radiation having a linear polarization angle θ1. The mode converter converts the linearly-polarized electromagnetic radiation to an orbital angular momentum (OAM) mode of linearly-polarized electromagnetic radiation with topological charge Li. The OAM mode of linearly-polarized electromagnetic radiation is a superposition of first and second OAM modes with topological charges Li and opposite circular polarizations. The optical fiber supports propagation of the first and second OAM modes with an absolute effective index difference Δneff greater than or equal to 5×10−5, such that linearly-polarized electromagnetic radiation with linear polarization angle θ2 is emitted by the optical fiber. The measurement device is configured to determine a property of the electromagnetic radiation based on the polarization angle θ2. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/866391 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/21 (20130101) G01N 21/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823668 | Nelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Karl D. Nelson (Plymouth, Minnesota); Matthew Wade Puckett (Scottsdale, Arizona); Neil Krueger (Saint Paul, Minnesota) |
| ABSTRACT | An apparatus is provided. The apparatus comprises a substrate; a low index of refraction region in or on the substrate; an optical waveguide; a cover; wherein at least a portion of the low index of refraction region and the optical waveguide are hermetically sealed under the cover; a chamber formed by the low index of refraction region and the cover; atoms; an environment, in the chamber, including the atoms and having a first index of refraction; a segment of the optical waveguide formed over the low index of refraction region and within the chamber; and wherein the segment has a second index of refraction which is substantially equal to the first index of refraction. |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 15/961478 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3103 (20130101) Original (OR) Class G01N 2021/3107 (20130101) Time-interval Measuring G04F 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823690 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nirmalkumar G. Patel (Jacksonville, Florida) |
| ASSIGNEE(S) | The University of North Florida Board of Trustees (Jacksonville, Florida) |
| INVENTOR(S) | Nirmalkumar G. Patel (Jacksonville, Florida) |
| ABSTRACT | A sensor for sensing gaseous chemicals includes a substrate, a variable resistance nanocrystalline ITO thin film formed on the substrate, and electrodes electrically coupled to the thin film. A sensor array assembly includes a sensor slide and a perforated interface circuit. The interface circuit abuts and electrically couples the sensor slide. The sensor slide includes several spaced apart ITO film strips formed on a slide substrate. A common electrode is electrically coupled to a common portion of each ITO film strip providing an electrically conductive path across the common portions of each of the plurality of spaced apart ITO film strips. A discrete electrode is electrically coupled to a discrete portion of each ITO film strip. The interface circuit is configured to abut and electrically couple to the sensor slide. A conductive discrete electrode pad electrically couples each of the plurality of discrete electrodes of the sensor slide to discrete terminals on the interface circuit. A conductive common electrode pad is associated with and electrically couples the common electrode of the sensor slide to a common electrode on the interface circuit. Apertures in the interface circuit expose the thin film to the environment. Resistance changes in a detectible manner upon exposure to sensible chemicals at ambient temperature, such as 1,2,2-Trimethylpropyl methylphosphonofluoridate (soman, GD), 0-Ethyl S-(2-isopropylaminoethyl) methylphosphonothiolate (VX), distilled bis(2-chloroethyl) sulfide (mustard, HD), carbonyl chloride, Phosgene (CG) and cyanogen chloride (CK), ozone, carbon monoxide, carbon dioxide, acetylene, propane, ammonia, sulfur dioxide, ethanol, methanol, volatile organic compounds and industrial toxic chemicals. |
| FILED | Wednesday, February 15, 2017 |
| APPL NO | 15/433643 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/125 (20130101) Original (OR) Class G01N 33/004 (20130101) G01N 33/0039 (20130101) G01N 33/0047 (20130101) G01N 33/0054 (20130101) G01N 33/0057 (20130101) Technologies for Adaptation to Climate Change Y02A 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823736 | Tseng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Hsian-Rong Tseng (Los Angeles, California); Jiaoti Huang (Los Angeles, California); Edwin M. Posadas (Los Angeles, California); Jiefu Chen (Los Angeles, California); Hao Ho (Los Angeles, California); Zunfu Ke (Los Angeles, California); Ker-Chau Li (Los Angeles, California); Yi-Tsung Lu (Los Angeles, California); Jake Lichterman (Los Angeles, California); Min Song (Los Angeles, California); Leland W. K. Chung (Los Angeles, California) |
| ABSTRACT | A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (CTCs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of CTCs; determining a measured CTC size distribution of the plurality of CTCs based on the measuring; comparing the measured CTC size distribution to a reference CTC size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing. |
| FILED | Monday, September 28, 2015 |
| APPL NO | 15/514438 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 15/1475 (20130101) G01N 33/56966 (20130101) G01N 33/57434 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2015/1006 (20130101) G01N 2015/1488 (20130101) G01N 2015/1493 (20130101) G01N 2015/1497 (20130101) G01N 2800/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823743 | Joseph et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | iFirst Medical Technologies, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | iFirst Medical Technologies, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Luke B. Joseph (Honolulu, Hawaii); Thomas A. Hasling (Honolulu, Hawaii) |
| ABSTRACT | A handheld medical analyzer works with different disposable application cartridges to perform a variety of interrogations on specimen samples. One application includes attaching a biological microelectromechanical systems (BioMEMS) cartridge that generates blood coagulation profiles indicative of particular forms of coagulation disorders. The device makes coagulopathy testing simpler for small hospitals, clinics, ambulances, remote locations and individuals and permits for a larger number of parallel or serial devices operating simultaneously. One insertion of a cartridge actuates an oscillating circular motion to generate a blood coagulation profile based on a change in rotational motion as blood coagulates in a sample. Change in rotational motion is analyzed through a video camera such as in a smartphone and is plotted to show an amplitude over time. Actuation of the BioMEMS can be achieved by magnetic actuation of a motor controlled by an iPhone or a smart phone to provide a specific rotational pattern. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/607105 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2300/041 (20130101) B01L 2300/0803 (20130101) B01L 2300/0848 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) Original (OR) Class G01N 2800/224 (20130101) G01N 2800/7033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823775 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rydberg Technologies Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Rydberg Technologies Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | David A. Anderson (Ann Arbor, Michigan); Georg A. Raithel (Ann Arbor, Michigan); Eric G. Paradis (Ann Arbor, Michigan); Rachel E. Sapiro (Ann Arbor, Michigan) |
| ABSTRACT | Methods and apparatus for sensing or measuring an electromagnetic field. The method entails excitation into a distribution of Rydberg states of atoms of a gas occupying a test volume coextensive with the electromagnetic field. Transmission along a path traversing the test volume of at least one probe beam of electromagnetic radiation is measured at one or more frequencies overlapping a spectral feature, and a physical characteristic of the electromagnetic field is derived on the basis of variation of the spectral feature. In various embodiments, the electromagnetic field may be place in interferometric relation with another electromagnetic field. Time-varying electric field amplitude, frequency, phase and noise spectral distribution may be measured, and thus AM and FM modulated fields, as well as magnetic fields of about 1 Tesla. The apparatus for measuring the electromagnetic field may be unilaterally coupled to a probe field and detector or array of detectors. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222384 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823813 | Parent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark G. Parent (Port Tobacco, Maryland); William Lee (Beltsville, Maryland) |
| ABSTRACT | An electromagnetic vector sensor (EMVS) system, having a plurality of EMVS devices consisting of a plurality of loop antenna elements spatially orthogonally integrated with and electrically isolated from a plurality of dipole antenna elements, mounted on a rotatably adjustable platform having a true north orientation, including active circuitry residing in antenna housings, and external executing software programs causing the active circuitry in cooperation with the EMVS device and receivers to determine angle of arrival and resolution of incoming wave vectors and polarization of incoming signals and to perform accurate high frequency geolocation signal processing; the programs which perform calibration and antenna element placement determination operations, also cause the system to collect data of known transmitted high frequency skywave signals, and estimate direction of arrival of unknown signals by detecting, resolving and measuring components of an electric field and a magnetic field at a single point. |
| FILED | Sunday, May 28, 2017 |
| APPL NO | 15/607527 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/40 (20130101) Original (OR) Class G01S 3/143 (20130101) G01S 19/40 (20130101) G01S 19/47 (20130101) Antennas, i.e Radio Aerials H01Q 1/125 (20130101) H01Q 7/00 (20130101) H01Q 9/22 (20130101) H01Q 21/06 (20130101) H01Q 21/24 (20130101) H01Q 21/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823843 | Kendra |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | John R. Kendra (Arlington, Virginia) |
| ABSTRACT | A process and systems for constructing arbitrarily large virtual arrays using two or more collection platforms (e.g. AUX and MOV systems) having differing velocity vectors. Referred to as Motion Extended Array Synthesis (MXAS), the resultant imaging system is comprised of the collection of baselines that are created between the two collection systems as a function of time. Because of the unequal velocity vectors, the process yields a continuum of baselines over some range, which constitutes an offset imaging system (OIS) in that the baselines engendered are similar to those for a real aperture of the same size as that swept out by the relative motion, but which are offset by some (potentially very large) distance. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789101 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/46 (20130101) G01S 13/589 (20130101) G01S 13/904 (20190501) G01S 13/9023 (20130101) Original (OR) Class G01S 13/9082 (20190501) G01S 13/9088 (20190501) G01S 2013/0254 (20130101) G01S 2013/468 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824045 | Rumpf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION (Orlando, Florida); THE UNIVERSITY OF TEXAS AT EL PASO (Austin, Texas) |
| INVENTOR(S) | Raymond C. Rumpf (El Paso, Texas); Stephen Kuebler (Orlando, Florida); Noel P. Martinez (El Paso, Texas); Cesar Luis Valle (El Paso, Texas) |
| ABSTRACT | Embodiments of the invention are directed compositions and devices that include a spatially-variant lattice (SVL), such as spatially variant photonic crystals (SVPC), as well as methods for making and using the same. In particular, the compositions and devices include SVPCs that are configured for manipulating the path and/or properties of electromagnetic radiation flowing through the SVPC in a variety of ways. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/627060 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/293 (20130101) Original (OR) Class G02F 2201/38 (20130101) G02F 2202/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824075 | Policastro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven A. Policastro (Waldorf, Maryland); Raymond C Y Auyeung (Alexandria, Virginia); Alberto Piqué (Crofton, Maryland); Farrel Martin (Waldorf, Maryland) |
| ABSTRACT | An apparatus for electrochemical experimentation with an isolated microstructural region on a surface comprising a metal sample coated with a photoresist, a region of interest, a light source, comprising optoelectronic devices such as spatial light modulators or digital micromirror devices for direct modulation of the light distribution itself and avoiding the use of a mask, wherein the exposed region is created by light from the light source and wherein the metal sample is immersed. A method for isolating microstructural regions or features on a surface for electrochemical experimentation comprising the steps of providing a metal sample, coating the metal sample, selecting a region of interest, creating exposed photoresist with direct modulation of the light distribution itself by optoelectronic devices such as spatial light modulators or digital micromirror devices and without a mask. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978992 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/16 (20130101) G03F 7/26 (20130101) G03F 7/2002 (20130101) Original (OR) Class G03F 7/2053 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/13 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824170 | Paduano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | AURORA FLIGHT SCIENCES CORPORATION (Manassas, Virginia) |
| INVENTOR(S) | James D. Paduano (Boston, Massachusetts); John B. Wissler (Waltham, Massachusetts); Michael D. Piedmonte (Stow, Massachusetts); David A. Mindell (Cambridge, Massachusetts) |
| ABSTRACT | An autonomous aerial vehicle includes a flight controller and a mission manager in communication with the flight controller. The flight controller is configured to navigate the autonomous aerial vehicle. The mission manager is configured to receive mission data. The mission data identifies both a landing zone and a designated touchdown zone located within the landing zone. The mission manager is further configured to provide flight control data to the flight controller. The flight control data causes the flight controller to navigate the autonomous aerial vehicle to a predetermined distance from the landing zone. The mission manager is further configured to determine, subsequent to the autonomous aerial vehicle reaching the predetermined distance, whether landing at the designated touchdown zone is feasible. The mission manager is further configured, in response to determining that landing at the designated touchdown zone is not feasible, to identify an alternate touchdown zone located within the landing zone for landing the autonomous aerial vehicle. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/379357 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) G05D 1/102 (20130101) Original (OR) Class G05D 1/0202 (20130101) G05D 1/0676 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) G06Q 10/08 (20130101) G06Q 50/28 (20130101) G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824172 | DeFelice et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); Peter J. Dowd (Granby, Connecticut) |
| ABSTRACT | A pneumatic controller for an inline valve includes a manifold with a set screw seated within it, a selector, and a biasing member. The manifold has a low pressure port, a high pressure port, and an actuator port. The selector is movable within the manifold between a first position and a second position, the low pressure port in fluid communication with the actuator port in the first position, the high pressure port in fluid communication with the actuator port in the second position. The biasing member urges the selector towards the first position with a biasing force and is spaced apart from the selector to limit eccentric force exerted on the selector. Inline valves and methods of controlling fluid flow through inline valves are also described. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447787 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) Non-positive-displacement Pumps F04D 27/0215 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0146 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) Y10T 137/3421 (20150401) Y10T 137/3476 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824871 | Thibeault et al. |
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| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Corey M. Thibeault (Encino, California); Narayan Srinivasa (Hillsboro, Oregon) |
| ABSTRACT | Described is a system and method for generating a unique signature for a space. During operation, the system causes a mobile platform to make one or more passes through the space along a repeatable path. While moving through the space, the system captures an image of the space around the mobile platform. A filter is applied to the image to generate vertical bins, the vertical bins being one-dimensional vectors of the space around the mobile platform. The one-dimensional vectors are combined over time to create a two-dimensional trace, with the two-dimensional trace being a unique signature for the space. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159488 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00691 (20130101) Original (OR) Class G06K 9/6269 (20130101) Pictorial Communication, e.g Television H04N 19/85 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825227 | Amer et al. |
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| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Mohamed R. Amer (Brooklyn, New York); Alex C. Tozzo (Philadelphia, Pennsylvania); Dejan Jovanovic (Brooklyn, New York); Timothy J. Meo (Kendall Park, New Jersey) |
| ABSTRACT | This disclosure describes techniques that include generating, based on a description of a scene, a movie or animation that represents at least one possible version of a story corresponding to the description of the scene. This disclosure also describes techniques for training a machine learning model to generate predefined data structures from textual information, visual information, and/or other information about a story, an event, a scene, or a sequence of events or scenes within a story. This disclosure also describes techniques for using GANs to generate, from input, an animation of motion (e.g., an animation or a video clip). This disclosure also describes techniques for implementing an explainable artificial intelligence system that may provide end users with information (e.g., through a user interface) that enables an understanding of at least some of the decisions made by the AI system. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230987 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/345 (20190101) G06F 16/738 (20190101) G06F 16/9024 (20190101) G06F 40/205 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00335 (20130101) G06K 9/00342 (20130101) G06K 9/00718 (20130101) G06K 9/00744 (20130101) G06K 9/6215 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 3/088 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 13/40 (20130101) G06T 13/80 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825604 | Chaparro |
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| FUNDED BY |
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| APPLICANT(S) | Jordan E. Chaparro (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jordan E. Chaparro (King George, Virginia) |
| ABSTRACT | An exemplary transformer is provided for high voltage and low leakage inductance, including an outer housing, a complementary pair of iron C-sections, bobbins and Litz wire. The iron C-sections form a magnetic loop core, forming proximal and distal sides. The bobbins include outer and inner primary bobbins, as well as outer, middle and inner secondary bobbins. The inner secondary bobbin has a center gap for receiving the proximal side of the core and is disposable within the inner primary bobbin. Inner and outer primary Litz wires have rectangular cross-sections and respectively wrap around the inner and outer primary bobbins. The secondary Litz wire contiguously wraps around the secondary bobbins. The primary Litz wires connect together by a shunt. The inner primary bobbin is disposable within the middle secondary bobbin. The middle secondary bobbin is disposable within the outer primary bobbin. The outer primary bobbin is disposable within the outer secondary bobbin. The outer secondary bobbin is disposable within the housing. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441127 |
| ART UNIT | 2839 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/02 (20130101) H01F 27/325 (20130101) Original (OR) Class H01F 27/2847 (20130101) H01F 2038/146 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/33546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825950 | Gregory et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James Gregory (Sudbury, Massachusetts); Christopher Leitz (Watertown, Massachusetts); Kevin Ryu (Arlington, Massachusetts); Donna-Ruth Yost (Acton, Massachusetts); Vladimir Bolkhovsky (Framingham, Massachusetts); Renee Lambert (Framingham, Massachusetts) |
| ABSTRACT | A new process that enables void-free direct-bonded MBE-passivated large-format image sensors is disclosed. This process can be used to produce thin large-area image sensors for UV and soft x-ray imaging. Such devices may be valuable in future astronomy missions or in the radiology field. Importantly, by controlling the hydrogen concentration in the silicon oxide layers of the image sensor and the support wafer, voids in the bonding interface can be significantly reduced or eliminated. This process can be applied to any wafer that includes active circuitry and requires a second wafer, such as a support wafer. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 16/411419 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/187 (20130101) H01L 21/2007 (20130101) H01L 27/14687 (20130101) H01L 27/14698 (20130101) H01L 27/14831 (20130101) H01L 33/005 (20130101) H01L 33/0093 (20200501) H01L 33/0095 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826184 | Logan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John T. Logan (Alexandria, Virginia); Rick W. Kindt (Arlington, Virginia) |
| ABSTRACT | Systems and methods are provided for Planar Ultrawideband Modular Antenna (PUMA) arrays that use slots as primary radiating mechanisms. Slot-based PUMA arrays in accordance with an embodiment of the present disclosure can achieve approximately the same performance as dipole-based PUMA arrays. Systems and methods according to embodiments of the present disclosure enable wideband slot-based antenna arrays that can be planar printed using etched metallic traces and plated through vias, have a single input per unit cell, and have unit cells that are coupled to radiating slot(s) that are continuous across multiple unit cells. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 16/420481 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/25 (20150115) H01Q 9/065 (20130101) Original (OR) Class H01Q 9/0478 (20130101) H01Q 21/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826199 | Fenn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan J. Fenn (Wayland, Massachusetts); Frank C. Robey (Concord, Massachusetts); Peter T. Hurst (Cambridge, Massachusetts); Mark J. Silver (Bedford, Massachusetts); Joseph M. D'Arco (Chelsea, Massachusetts) |
| ABSTRACT | The present invention generally relates to an electromagnetic field vector sensing receive antenna array system for installation and deployment on a structure. A multipolarized array of collocated antenna elements is used to provide calibrated amplitude and phase radiation patterns with monopole, dipole, and loop modes generated from crossed loops connected to a beamformer. The invention has applications for installation and deployment on a tower, balloon, satellite for radio frequency sensing and location of low-frequency galactic emissions. The novel receive antenna array system comprises a multipolarized vector sensor antenna array. The disclosed direction-finding vector sensor can be installed and deployed on a structure and can detect and locate radio frequency emissions from galactic sources. The key system components of the receive antenna array system consist of deployable antennas, receivers, signal processing computer, and communications link. |
| FILED | Wednesday, February 13, 2019 |
| APPL NO | 16/274675 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/18 (20130101) G01S 3/143 (20130101) Antennas, i.e Radio Aerials H01Q 1/14 (20130101) H01Q 1/288 (20130101) H01Q 5/48 (20150115) H01Q 7/02 (20130101) H01Q 7/005 (20130101) H01Q 21/24 (20130101) H01Q 21/29 (20130101) H01Q 21/245 (20130101) H01Q 25/04 (20130101) Original (OR) Class Transmission H04B 7/0617 (20130101) H04B 7/0885 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826517 | Vaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xilinx, Inc. (San Jose, California) |
| ASSIGNEE(S) | XILINX, INC. (San Jose, California) |
| INVENTOR(S) | Bruno Miguel Vaz (Sao Domingos de Rana, Portugal); John E. McGrath (Cahir, Ireland); Conrado K. Mesadri (San Jose, California); Woon C. Wong (Dublin, California); Ali Boumaalif (City Cork Centre, Ireland); Christopher Erdman (Dublin, Ireland); Brendan Farley (Donobate, Ireland) |
| ABSTRACT | An integrated circuit is described. The integrated circuit comprises an analog-to-digital converter circuit configured to receive an input signal at an input and generate an output signal at an output; and a monitor circuit coupled to the output of the analog-to-digital converter circuit, the monitor circuit configured to receive the output signal and to generate integration coefficients for the analog-to-digital converter circuit; wherein the integration coefficients are dynamically generated based upon signal characteristics of the output signal generated by the analog-to-digital converter circuit. A method of receiving data in an integrated circuit is also described. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 16/680356 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/318519 (20130101) Coding; Decoding; Code Conversion in General H03M 1/1071 (20130101) H03M 1/1215 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/43 (20130101) H04L 12/433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826746 | James et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Justin O. James (San Diego, California); Michael P. Daly (San Diego, California) |
| ABSTRACT | A transmitter adjustment value for adjusting modulations at a transmitter may be determined. The transmitter may be configured to transmit in accordance with an asymmetric signal constellation, based on the determined transmitter adjustment value. A legitimate receiver may be provided with a receiver adjustment value corresponding to the determined transmitter adjustment value. At the transmitter, scrambled transmissions may be transmitted, based on transmitting using the determined transmitter adjustment value. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808700 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0041 (20130101) H04L 27/0008 (20130101) H04L 27/183 (20130101) H04L 27/3405 (20130101) H04L 27/3488 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826902 | Aksu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Hidayet Aksu (Eruh, Turkey); A. Selcuk Uluagac (Dinar, Turkey); Elizabeth S. Bentley (Clinton, New York) |
| ABSTRACT | A wireless Internet-of-Things (IoT) device identification method and framework incorporates machine learning (ML) techniques with information from the protocol used (e.g., Bluetooth, Bluetooth Low Energy/Bluetooth Smart, and others). A passive, non-intrusive feature selection technique targets IoT device captures with an ML classifier selection algorithm for the identification of IoT devices (i.e., picking the best performing ML algorithm among multiple ML algorithms available). Using an input training label and training dataset (e.g., training wireless IoT packets) associated with the IoT device, a classifier and a filter are selected. An inter-arrival-time (IAT) associated with the filtered training data set and a density distribution for the IAT are then calculated. After converting the density distribution to the training feature vector, a prediction model and the selected classifier are stored for subsequent application to testing datasets to detect and display an association of the testing dataset to a matched IoT device (i.e., identification). |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 15/909044 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) H04L 63/0876 (20130101) Original (OR) Class H04L 67/12 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827190 | Blasch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Rome, New York) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Erik Philip Blasch (Rome, New York); Hua-Mei Harry Chen (Gaithersburg, Maryland); Zhonghai Wang (Boyds, Maryland); Genshe Chen (Germantown, Maryland); Kui Liu (Germantown, Maryland); Dan Shen (Germantown, Maryland) |
| ABSTRACT | A framework for estimating image interpretability degradation associated with image compression is provided. An image compression broker system can determine an image compression setting to achieve an interpretability task in accordance with available communication bandwidth or transmission time objectives. Estimating image interpretability degradation includes detecting edge points of an uncompressed image and determining gradients corresponding to the detected edge points; compressing in accordance with a compression parameter setting the uncompressed image to generate a compressed image and determining gradients corresponding to the edge points in the compressed image; determining from the gradients associated with the edge points gradient ratios; and estimating from the gradient ratios an image interpretability loss of the compressed image. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915160 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/13 (20170101) Pictorial Communication, e.g Television H04N 19/42 (20141101) Original (OR) Class H04N 19/85 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827503 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Junshan Zhang (Tempe, Arizona); Xu Chen (Tempe, Arizona); Zhengyu Zhang (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Junshan Zhang (Tempe, Arizona); Xu Chen (Tempe, Arizona); Zhengyu Zhang (Tempe, Arizona) |
| ABSTRACT | A plurality of mobile devices is provided including a first mobile device of the plurality of mobile devices that serves as a relay for communication between a second mobile device of the plurality of mobile devices and a third mobile device of the plurality of mobile devices. The first mobile device is identified as the relay based on a social trust relationship formed between the first mobile device and the second mobile device. A D2D network is formed between the first mobile device and second mobile device. A communication channel is provided to the second mobile device from a second cellular network. A portion of the communication channel is allocated to the second mobile device using the D2D network to improve cellular transmission between the second mobile device and the third mobile device. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170937 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Wireless Communication Networks H04W 4/21 (20180201) H04W 8/005 (20130101) H04W 40/22 (20130101) H04W 48/16 (20130101) H04W 72/048 (20130101) Original (OR) Class H04W 72/0453 (20130101) H04W 76/14 (20180201) H04W 88/04 (20130101) H04W 88/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827601 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Surfx Technologies LLC (Redondo Beach, California) |
| ASSIGNEE(S) | Surfx Technologies LLC (Redondo Beach, California) |
| INVENTOR(S) | Thomas Scott Williams (Long Beach, California); George Suarez (West Sacramento, California); Mikhail Grigoriev (Gardena, California); Robert F. Hicks (Los Angeles, California) |
| ABSTRACT | A handheld plasma tool for controlled application of low temperature atmospheric pressure plasma to material surfaces, e.g. to enhance bonding and or cleaning. The handheld plasma tool can include a hand grip, on/off trigger, display, indicator lights, indexing pin, marking device, cable connections for gas supply and electrical power, and a plasma head for generating at least one reactive gas species at a low temperature. The handheld plasma tool can employ a rotatable clamp for treating backside surfaces. The handheld plasma tool can include motorized wheels to scan over a large area at a controlled speed. Other optional nozzles can also be employed for specialized applications. |
| FILED | Wednesday, May 03, 2017 |
| APPL NO | 15/586223 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class H05H 2001/4645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10820596 | Gruver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| ASSIGNEE(S) | PIONEER HI-BRED INTERNATIONAL, INC. (, Iowa) |
| INVENTOR(S) | Steven D Gruver (Pacifica, California); Heather Kozy (Walnut Creek, California); Jessica O'Rear (Redwood City, California); Barbara Rosen (Mountain View, California); Ute Schellenberger (Palo Alto, California); Jun-Zhi Wei (Hayward, California); Weiping Xie (East Palo Alto, California); Xiaohong Zhong (San Leandro, California); Genhai Zhu (San Jose, California) |
| ABSTRACT | Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 16/567200 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 63/10 (20200101) Original (OR) Class Peptides C07K 14/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8286 (20130101) Technologies for Adaptation to Climate Change Y02A 40/162 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821195 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Jason S. Lewis (New York, New York); Melissa Deri (Hottsville, New York); Lynn Francesconi (Bridgewater, New Jersey); Shashikanth Ponnala (Secaucus, New Jersey) |
| ABSTRACT | Described herein is a chelator for radiolabels (e.g., 89Zr) for targeted PET imaging that is an alternative to DFO. In certain embodiments, the chelator for 89Zr is the ligand, 3,4,3-(LI-1,2-HOPO) (“HOPO”), which exhibits equal or superior stability compared to DFO in chemical and biological assays across a period of several days in vivo. As shown in FIG. 1, the HOPO is an octadentate chelator that stabilizes chelation of radiolabels (e.g., 89Zr). A bifunctional ligand comprising p-SCN-Bn-HOPO is shown in FIG. 4 and FIG. 5. Such a bifunctional ligand can eliminate (e.g., 89Zr) loss from the chelate in vivo and reduce uptake in bone and non-target tissue. Therefore, the bifunctional HOPO ligand can facilitate safer and improved PET imaging with radiolabeled antibodies. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/759154 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class A61K 51/1051 (20130101) A61K 51/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821393 | Elliott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Exxonmobil Research and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | Exxonmobil Research and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Jeannine Elizabeth Elliott (Superior, Colorado); Robert James Copeland (Arvada, Colorado); Jeff Lind (Arvada, Colorado); Daniel P. Leta (Flemington, New Jersey); Patrick P. McCall (Matawan, New Jersey) |
| ABSTRACT | A system and method for separating and/or purification of CO2 gas from a CO2 feed stream is described. The system and method include a plurality of fixed sorbent beds, adsorption zones and desorption zones, where the sorbent beds are connected via valve and lines to create a simulated moving bed system, where the sorbent beds move from one adsorption position to another adsorption position, and then into one regeneration position to another regeneration position, and optionally back to an adsorption position. The system and method operate by concentration swing adsorption/desorption and by adsorptive/desorptive displacement. |
| FILED | Thursday, August 11, 2016 |
| APPL NO | 15/234772 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/06 (20130101) B01D 53/10 (20130101) B01D 53/0446 (20130101) Original (OR) Class B01D 2253/104 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2259/402 (20130101) B01D 2259/4009 (20130101) B01D 2259/4065 (20130101) B01D 2259/4067 (20130101) B01D 2259/40003 (20130101) B01D 2259/40086 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821599 | Crawford |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Anthony L. Crawford (Rigby, Idaho) |
| ABSTRACT | A dual linear delta assembly includes a frame, a first linear delta system, and a second linear delta system concentric with the first linear delta system. Each of the first linear delta system and the second linear delta system may include rails mounted to the frame, linear actuators, each linear actuator coupled to a respective rail of the rails and configured to translate along a longitudinal length of the respective rail, pairs of parallel rods each operably coupled to a respective linear actuator of the linear actuators, and a platform coupled to a longitudinal end of each of the pairs of parallel rods opposite the respective linear actuator of the linear actuators. |
| FILED | Wednesday, November 14, 2018 |
| APPL NO | 16/191093 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/009 (20130101) Original (OR) Class B25J 9/0048 (20130101) Gearing F16H 25/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821657 | Wexler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Jason Stein Wexler (San Francisco, California); Kevin Kai Morris (Tiburon, California); Rustie Nate McCumber (Oakland, California) |
| ABSTRACT | A method of selecting a braid configuration for a braided liner. The method includes calculating a size ratio based on the smallest first diameter and the largest second diameter of the liner and selecting a braid material having a tensile strength. The method further includes calculating a strength ratio based on the tensile strength of the braid material and a selected target strength threshold for the braided liner and determining an optimal braid angle for the smallest first diameter portions of the liner based on the calculated size ratio. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 15/627814 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 15/122 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 53/083 (20130101) B29C 63/04 (20130101) B29C 63/06 (20130101) Original (OR) Class B29C 63/105 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/08 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/085 (20130101) B29L 2031/712 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/00 (20130101) F17C 1/06 (20130101) F17C 2201/056 (20130101) F17C 2201/058 (20130101) F17C 2201/0138 (20130101) F17C 2203/0619 (20130101) F17C 2203/0663 (20130101) F17C 2205/0111 (20130101) F17C 2205/0332 (20130101) F17C 2209/2154 (20130101) F17C 2221/033 (20130101) F17C 2223/036 (20130101) F17C 2223/0123 (20130101) F17C 2260/017 (20130101) F17C 2260/018 (20130101) F17C 2270/0168 (20130101) F17C 2270/0178 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/523 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822246 | Suib et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Steven L. Suib (Storrs, Connecticut); Zhu Luo (Wuhan, China PRC) |
| ABSTRACT | This disclosure provides a unique approach for the synthesis of non-stoichiometric, mesoporous metal oxides with nano-sized crystalline wall. The as-synthesized mesoporous metal oxide is very active and stable (durability >11 h) electocatalyst in both acidic and alkaline conditions. The intrinsic mesoporous metal oxide serves as an electrocatalyst without the assistant of carbon materials, noble metals, or other materials, which are widely used in previously developed systems. The as-synthesized mesoporous metal oxide has large accessible pores (2-50 nm), which are able to facilitate mass transport and charge transfer. The as-synthesized mesoporous metal oxide requires a low overpotential and is oxygen deficient. Oxygen vacancies and mesoporosity served as key factors for excellent performance. |
| FILED | Friday, May 19, 2017 |
| APPL NO | 15/600432 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/04 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/46 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/483 (20130101) H01M 4/8605 (20130101) H01M 4/9016 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822364 | Dinca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mircea Dinca (Belmont, Massachusetts); Dennis Sheberla (Watertown, Massachusetts); Lei Sun (Cambridge, Massachusetts); Casey R. Wade (Waltham, Massachusetts); Michael Glenn Campbell (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods comprising metal organic frameworks (MOFs) and related uses are generally provided. In some embodiments, a MOF comprises a plurality of metal ions, each coordinated with at least one ligand comprising at least two sets of ortho-diimine groups arranged about an organic core. |
| FILED | Friday, January 04, 2019 |
| APPL NO | 16/240629 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/005 (20130101) C07F 1/08 (20130101) C07F 15/045 (20130101) Original (OR) Class C07F 15/065 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822623 | Bowie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James U. Bowie (Culver City, California); Paul H. Opgenorth (Los Angeles, California); Tyler P. Korman (Sierra Madre, California) |
| ABSTRACT | The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243332 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class C12P 7/625 (20130101) Enzymes C12Y 102/01051 (20130101) C12Y 106/99001 (20130101) C12Y 108/01004 (20130101) C12Y 203/01012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822634 | Northen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Trent R. Northen (Walnut Creek, California); Kai Deng (Orinda, California) |
| ABSTRACT | A method for rapid, high throughput screening of the activities of enzymes, especially ligninases and its enzyme cocktails, using nanostructure initiator mass spectrometry (NIMS) surfaces, substrates and methodology. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499769 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) Original (OR) Class C12Q 1/28 (20130101) C12Q 1/34 (20130101) Enzymes C12Y 110/03002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2333/908 (20130101) G01N 2333/924 (20130101) G01N 2333/90232 (20130101) G01N 2560/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822670 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim Karaman (College Stationi, Texas); Raymundo Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/217594 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) B23K 2101/16 (20180801) B23K 2103/04 (20180801) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) F27D 2007/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822709 | Kuhl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Opus 12 Incorporated (Berkeley, California) |
| ASSIGNEE(S) | Opus 12 Incorporated (Berkeley, California) |
| INVENTOR(S) | Kendra P. Kuhl (Berkeley, California); Etosha R. Cave (Berkeley, California); George Leonard (Berkeley, California) |
| ABSTRACT | A platform technology that uses a novel membrane electrode assembly, including a cathode layer, an anode layer, a membrane layer arranged between the cathode layer and the anode layer, the membrane conductively connecting the cathode layer and the anode layer, in a COx reduction reactor has been developed. The reactor can be used to synthesize a broad range of carbon-based compounds from carbon dioxide and other gases containing carbon. |
| FILED | Wednesday, May 03, 2017 |
| APPL NO | 15/586182 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) C25B 9/10 (20130101) Original (OR) Class C25B 11/0405 (20130101) C25B 11/0415 (20130101) C25B 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822968 | Jordan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Eric Jordan (Storrs, Connecticut); Rishi Kumar (Ashford, Connecticut) |
| ABSTRACT | Thermal barrier coatings and methods to make such coatings present improved resistance to CMAS infiltration. The method for forming a thermal barrier coating includes applying a layer of the thermal barrier coating to a component having a surface, forming a plurality of first channels in the thermal barrier coating, and forming a plurality of second channels in the thermal barrier coating. The first channels extend through a thickness of the thermal barrier coating from an interface with the surface of the component to a free surface opposite the interface. The second channels are disposed between the free surface and the interface and extending lengthwise generally parallel to the free surface of the thermal barrier coating. |
| FILED | Saturday, June 08, 2019 |
| APPL NO | 16/435484 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/134 (20160101) C23C 14/28 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823134 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| INVENTOR(S) | David G. Wilson (Tijeras, New Mexico); Giorgio Bacelli (Albuquerque, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Ossama Abdelkhalik (Houghton, Michigan) |
| ABSTRACT | The present invention is directed to a nonlinear controller for nonlinear wave energy converters (WECs). As an example of the invention, a nonlinear dynamic model is developed for a geometrically right-circular cylinder WEC design for the heave-only motion, or a single degree-of-freedom (DOF). The linear stiffness term is replaced by a nonlinear cubic hardening spring term to demonstrate the performance of a nonlinear WEC as compared to an optimized linear WEC. By exploiting the nonlinear physics in the nonlinear controller, equivalent power and energy capture, as well as simplified operational performance is observed for the nonlinear cubic hardening spring controller when compared to an optimized linear controller. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/534746 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823405 | Alekseev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LINDE AKTIENGESELLSCHAFT (Munich, Germany) |
| ASSIGNEE(S) | Linde Aktiengesellschaft (Munich, Germany) |
| INVENTOR(S) | Alexander Alekseev (Wolfratshausen, Germany); Stevan Jovanovic (North Plainfield, New Jersey) |
| ABSTRACT | Integration of an oxyfuel combustion boiler at elevated pressures and a heat exchanger is achieved to produce carbon dioxide by feeding flue gas comprising carbon dioxide and water from the oxyfuel combustion boiler to a direct contact cooler column wherein water is condensed at a temperature of 0 to 10° C. lower than its dew point; feeding a portion of the condensed water from the direct contact cooler column to the oxyfuel combustion boiler; feeding a portion of the carbon dioxide from the direct contact cooler column to the oxyfuel combustion boiler; and recovering a portion of the carbon dioxide from the direct contact cooler column. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/773299 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 17/025 (20130101) F01K 23/10 (20130101) Methods of Steam Generation; Steam Boilers F22B 35/00 (20130101) F22B 35/007 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 9/08 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) Original (OR) Class F23L 2900/07005 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823664 | Morrow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Darien James Morrow (Madison, Wisconsin); Daniel David Kohler (Madison, Wisconsin); John Curtis Wright (Oregon, Wisconsin) |
| ABSTRACT | Methods for pump-probe spectroscopy are provided. In an embodiment, such a method comprises directing pump light having a frequency ωpump at a location in a sample to excite a transition between two quantum states of a target entity in the sample, directing probe light at the location to generate a coherent output signal having a frequency ωoutput and a wavevector koutput, and detecting the output signal as the probe light is scanned over a range of frequencies. In the method, either the transition excited by the pump light is a multiphoton transition corresponding to a frequency difference of n*ωpump, wherein n≥2; or the probe light is a set of m coherent light pulses, each coherent light pulse having a frequency ωm and a wavevector km, wherein m≥2; or both. Systems for carrying out the methods are also provided. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/446750 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/255 (20130101) Original (OR) Class G01N 21/636 (20130101) G01N 2021/1791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823667 | Ramachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Gautam Prabhakar (Boston, Massachusetts); Aaron G. Peterson-Greenberg (Cambridge, Massachusetts) |
| ABSTRACT | A system comprises an electromagnetic radiation source, a polarizing element, a mode converter, an optical fiber, and a measurement device. The polarizing element receives electromagnetic radiation produced by the electromagnetic radiation source and outputs linearly-polarized electromagnetic radiation having a linear polarization angle θ1. The mode converter converts the linearly-polarized electromagnetic radiation to an orbital angular momentum (OAM) mode of linearly-polarized electromagnetic radiation with topological charge Li. The OAM mode of linearly-polarized electromagnetic radiation is a superposition of first and second OAM modes with topological charges Li and opposite circular polarizations. The optical fiber supports propagation of the first and second OAM modes with an absolute effective index difference Δneff greater than or equal to 5×10−5, such that linearly-polarized electromagnetic radiation with linear polarization angle θ2 is emitted by the optical fiber. The measurement device is configured to determine a property of the electromagnetic radiation based on the polarization angle θ2. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/866391 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/21 (20130101) G01N 21/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825571 | Edwards et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Tyler A. Edwards (Simi Valley, California); Michael J. Edwards (Forest, Virginia) |
| ABSTRACT | A nuclear island includes a nuclear reactor, a lateral seismic restraint, and a reactor core retention cooling system. The lateral seismic restraint includes a vertically oriented pin attached to one of the bottom of the lower vessel head and the floor underneath the nuclear reactor, and a mating pin socket is attached to the other of the bottom of the lower vessel head and the floor. The reactor core retention cooling system includes one or more baffles, optionally thermally insulating material, disposed alongside the exterior surface of a lower portion of the reactor pressure vessel including at least the lower vessel head. A plenum is defined between the one or more baffles and the exterior surface of a lower portion of the reactor pressure vessel. The one or more baffles may define a lower plenum inlet surrounding the lateral seismic restraint. |
| FILED | Monday, August 14, 2017 |
| APPL NO | 15/675850 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 5/10 (20130101) G21C 9/016 (20130101) G21C 13/024 (20130101) Original (OR) Class G21C 15/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826050 | Kaehr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Duracell U.S. Operations, Inc. (Wilmington, Delaware) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Duracell U.S. Operations, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Bryan James Kaehr (Albuquerque, New Mexico); Walter F. Paxton (Albuquerque, New Mexico); Adam Cook (Albuquerque, New Mexico); William Reinholtz (Albuquerque, New Mexico); Michael Pozin (Brookfield, Connecticut) |
| ABSTRACT | The present invention relates, in part, to methods of preparing a safety battery. Methods can include dispensing a safety ink formulation between the two poles of a battery. Upon exposure to moisture, the formulation provides an electrical connection between two poles, thus minimizing electrical discharge and/or reducing the formation of electrochemically generated ions at the pole(s). |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/016452 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/34 (20130101) Original (OR) Class H01M 10/0436 (20130101) H01M 2200/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826065 | Kozen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Alexander C. Kozen (College Park, Maryland); Marshall A. Schroeder (Sykesville, Maryland); Gary W. Rubloff (Clarksville, Maryland); Liangbing Hu (Hyattsville, Maryland); Malakhi Noked (Rockville, Maryland); Sang Bok Lee (Clarksville, Maryland) |
| ABSTRACT | A protection layer is formed on a highly-reactive substantially-pure metal anode to a thickness of between 1 nm and 200 nm, inclusive, using atomic layer deposition (ALD). The ALD protection layer allows the conduction of ions of the metal of the anode therethrough but suppresses electron transport therethrough. The ALD protection layer may also be effective to inhibit passage of air and/or water therethrough. The ALD protection layer can allow more relaxed purity requirements for subsequent battery assembly, electrolyte specifications, and/or cathode gas purity. Fabrication methods for the protection layers, protected metal anodes, and systems and devices incorporating such protected metal anodes are also disclosed herein. |
| FILED | Monday, October 05, 2015 |
| APPL NO | 15/517126 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) Original (OR) Class H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/1395 (20130101) H01M 10/05 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826076 | Macauley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Natalia Macauley (Los Alamos, New Mexico); Siddharth Komini Babu (Santa Fe, New Mexico); Rangachary Mukundan (Los Alamos, New Mexico); Mahlon S. Wilson (Los Alamos, New Mexico); Rodney L. Borup (Los Alamos, New Mexico); Stephen Grot (New Castle, Delaware) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Natalia Macauley (Los Alamos, New Mexico); Siddharth Komini Babu (Santa Fe, New Mexico); Rangachary Mukundan (Los Alamos, New Mexico); Mahlon S. Wilson (Los Alamos, New Mexico); Rodney L. Borup (Los Alamos, New Mexico); Stephen Grot (New Castle, Delaware) |
| ABSTRACT | Disclosed herein are embodiments of a patterned electrode comprising regions of catalyst and segregating regions that separate the regions of catalyst. The segregating regions may be regions of non-catalytic material. The catalyst regions may correspond to the channels of a flow field. The electrode provides improved fuel cell performance, particularly at high current densities. The electrode may be for all suitable applications, such as in a membrane electrode assembly and/or a fuel cell. Also disclosed is a method for making the patterned electrode. The method may comprise using masks to apply the catalyst and non-catalyst material to a substrate. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057485 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) Original (OR) Class H01M 4/8663 (20130101) H01M 4/8807 (20130101) H01M 8/1004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10826114 — Cathodes and electrolytes for rechargeable magnesium batteries and methods of manufacture
| US 10826114 | Kumta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Partha Saha (Pittsburgh, Pennsylvania); Moni Kanchan Datta (Pittsburgh, Pennsylvania); Ayyakkannu Manivannan (Morgantown, West Virginia) |
| ABSTRACT | The invention relates to Chevrel-phase materials and methods of preparing these materials utilizing a precursor approach. The Chevrel-phase materials are useful in assembling electrodes, e.g., cathodes, for use in electrochemical cells, such as rechargeable batteries. The Chevrel-phase materials have a general formula of Mo6Z8 and the precursors have a general formula of MxMo6Z8. The cathode containing the Chevrel-phase material in accordance with the invention can be combined with a magnesium-containing anode and an electrolyte. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897721 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/006 (20130101) C01G 39/06 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/30 (20130101) C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/77 (20130101) C01P 2004/38 (20130101) C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/581 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) Original (OR) Class H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826132 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kandler Alan Smith (Golden, Colorado); Jeremy Stephan Neubauer (Sunnyvale, California); Shriram Santhanagopalan (Broomfield, Colorado); Andrew Michael Colclasure (Morrison, Colorado); Lei Cao (Arvada, Colorado) |
| ABSTRACT | An aspect of the present disclosure is an electrochemical device that includes a first electrode, an ion reservoir electronically connected to the electrode by a first circuit, an electrolyte positioned between the first electrode and the ion reservoir and ionically connecting the first electrode and the ion reservoir, and a regulating element, where the regulating element is positioned between the first electrode and the ion reservoir, the regulating element electronically and/or ionically connects the ion reservoir and the first electrode, and the regulating element limits the transfer of at least one of electrons and/or ions between the ion reservoir and the first electrode. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 15/685485 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/05 (20130101) H01M 10/0525 (20130101) H01M 10/4242 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826563 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ABL IP Holding, LLC (Conyers, Georgia) |
| ASSIGNEE(S) | ABL IP Holding, LLC (Conyers, Georgia) |
| INVENTOR(S) | Jeffrey Michael Scott (San Pablo, California); Michael Miu (Castro Valley, California) |
| ABSTRACT | A method for auto-commissioning of multiple device control modules on a power line during the power up of the system. Device control modules associated with the peripheral devices are powered up sequentially and a unique address is assigned to each device controller when it is powered up. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/181165 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Transmission H04B 3/58 (20130101) H04B 3/542 (20130101) Original (OR) Class H04B 3/546 (20130101) H04B 3/548 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/00 (20200101) H05B 47/185 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826922 | Mestha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Lalit Keshav Mestha (North Colonie, New York); Hema Kumari Achanta (Schenectady, New York); Justin Varkey John (Niskayuna, New York); Cody Joe Bushey (Clifton Park, New York) |
| ABSTRACT | In some embodiments, an industrial asset may be associated with a plurality of monitoring nodes, each monitoring node generating a series of monitoring node values over time that represent operation of the industrial asset. A threat detection computer may determine that an attacked monitoring node is currently being attacked. Responsive to this determination, a virtual sensor coupled to the plurality of monitoring nodes may estimate a series of virtual node values for the attacked monitoring node(s) based on information received from monitoring nodes that are not currently being attacked. The virtual sensor may then replace the series of monitoring node values from the attacked monitoring node(s) with the virtual node values. Note that in some embodiments, virtual node values may be estimated for a particular node even before it is determined that the node is currently being attacked. |
| FILED | Monday, November 11, 2019 |
| APPL NO | 16/679749 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/50 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) G06F 21/577 (20130101) G06F 2221/2101 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/62 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/145 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) H04L 63/1441 (20130101) H04L 63/1466 (20130101) H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826932 | Abbaszadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Masoud Abbaszadeh (Clifton Park, New York); Lalit Keshav Mestha (North Colonie, New York) |
| ABSTRACT | A plurality of monitoring nodes may each generate a time-series of current monitoring node values representing current operation of a cyber-physical system. A feature-based forecasting framework may receive the time-series of and generate a set of current feature vectors using feature discovery techniques. The feature behavior for each monitoring node may be characterized in the form of decision boundaries that separate normal and abnormal space based on operating data of the system. A set of ensemble state-space models may be constructed to represent feature evolution in the time-domain, wherein the forecasted outputs from the set of ensemble state-space models comprise anticipated time evolution of features. The framework may then obtain an overall features forecast through dynamic ensemble averaging and compare the overall features forecast to a threshold to generate an estimate associated with at least one feature vector crossing an associated decision boundary. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/108742 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6232 (20130101) G06K 9/6261 (20130101) G06K 9/6269 (20130101) G06K 9/6298 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 7/005 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826994 | Frigo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Janette Frigo (Santa Fe, New Mexico); Stephen Judd (Los Alamos, New Mexico); Michael Proicou (Los Alamos, New Mexico); Kevin McCabe (Santa Fe, New Mexico); Donald Enemark (Los Alamos, New Mexico); Alexandra Saari (Santa Barbara, California); Shawn Hinzey (Los Alamos, New Mexico) |
| ABSTRACT | A sensor system may be configured for continuous operation in a low resource environment and/or in extreme environmental conditions. The sensor system may have sufficient processing capabilities to provide scientific computing for pre-processing, quality control, statistical analysis, event classification, data compression and corrections (e.g., spikes in the data), autonomous decisions and actions, triggering other nodes, and information assurance functions that provide data confidentiality, data integrity, authentication, and non-repudiation. The hardware may have both mesh networking and satellite and cellular communication capability, and may be available for relatively low cost. Such a network provides the flexibility to have potentially any number of nodes be completely independent from one another. Thus, the network may scale across a diverse terrain. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/014084 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 9/32 (20130101) Transmission H04B 7/15507 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) Original (OR) Class Wireless Communication Networks H04W 52/0258 (20130101) H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10820588 | Hamers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert John Hamers (Madison, Wisconsin); Jaya Borgatta (Brooklyn, New York) |
| ABSTRACT | Provided are compositions which may be used in agricultural applications. Also provided are methods of making and using the compositions. In embodiments, a plant fungicide or plant bactericide is provided comprising a nanostructured chemical compound, the chemical compound comprising a metal and a coordinating anion, wherein the nanostructured chemical compound is in the form of a plurality of planar, two-dimensional nanostructures. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 16/549005 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) Original (OR) Class A01N 59/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820818 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bin He (Arden Hills, Minnesota); Zhaoye Zhou (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for non-invasively generating a report of cardiac electrical activities of a subject includes determining, using cardiac electrical activation information, equivalent current densities (ECDs). The ECDs are assembled into time-course ECD information and a spectrum of the time-course ECD information is analyzed to determine peaks for spectral characteristics of atrial fibrillation (AF). The spectral characteristics of AF are correlated with potential electrical sources of the AF and a report is generated indicating the potential electrical sources of the AF spatially registered with the medical imaging data. |
| FILED | Wednesday, January 18, 2017 |
| APPL NO | 15/409395 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/0044 (20130101) A61B 5/046 (20130101) A61B 5/055 (20130101) A61B 5/0432 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/7278 (20130101) A61B 5/7289 (20130101) A61B 6/032 (20130101) A61B 6/507 (20130101) A61B 2576/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820862 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); WASHINGTON UNIVERSITY IN ST. LOUIS (St. Louis, Missouri) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Igor Efimov (Wildwood, Missouri); Sarah Gutbrod (St. Louis, Missouri); Lizhi Xu (Urbana, Illinois); Andrew Bonifas (Woodbury, Minnesota); Richard Chad Webb (Urbana, Illinois); Ahyeon Koh (Champaign, Illinois) |
| ABSTRACT | Provided are devices and methods capable of interfacing with biological tissues, such as organs like the heart, in real-time and using techniques which provide the ability to monitor and control complex physical, chemical, biochemical and thermal properties of the tissues as a function of time. The described devices and methods utilize micro scale sensors and actuators to spatially monitor and control a variety of physical, chemical and biological tissue parameters, such as temperature, pH, spatial position, force, pressure, electrophysiology and to spatially provide a variety of stimuli, such as heat, light, voltage and current. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 14/504736 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/015 (20130101) A61B 5/0036 (20180801) A61B 5/036 (20130101) A61B 5/0084 (20130101) A61B 5/0422 (20130101) A61B 5/0538 (20130101) A61B 5/686 (20130101) A61B 5/1107 (20130101) A61B 5/1116 (20130101) A61B 5/1473 (20130101) A61B 5/02055 (20130101) A61B 5/4836 (20130101) A61B 5/6843 (20130101) A61B 5/6869 (20130101) A61B 5/6885 (20130101) Original (OR) Class A61B 5/14539 (20130101) A61B 5/14546 (20130101) A61B 18/14 (20130101) A61B 2018/00351 (20130101) A61B 2562/028 (20130101) A61B 2562/046 (20130101) A61B 2562/164 (20130101) A61B 2562/0215 (20170801) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/007 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0245 (20130101) A61H 2201/10 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/375 (20130101) A61N 1/0563 (20130101) A61N 1/0597 (20130101) A61N 1/3621 (20130101) A61N 1/37512 (20170801) A61N 2/002 (20130101) A61N 2/006 (20130101) A61N 5/0603 (20130101) A61N 5/0622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10820914 | Pak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Nikita Pak (Allston, Massachusetts); Justin P. Kinney (Quincy, Massachusetts); Edward S. Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method for automated opening of craniotomies includes, under the control of a computer processor, drilling into a skull for a predetermined distance and determining when there is a conductance drop near the drilling tip that indicates skull breakthrough. If the conductance is not below a predetermined threshold, drilling continues iteratively manner until conductance is below the threshold. A craniotomy pattern may be predetermined and automatically drilled under control of the processor. A cranial window may be created by drilling along a path that interpolates between holes to form the circumference of the window. An automated craniotomy opening apparatus includes a drilling apparatus with a drilling tip, at least one drilling apparatus positioning device, a detection device, and a computer processor that controls the drilling apparatus, the positioning device, and the detection device according to the method. Determining conductance may include use of an impedance detection circuit. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/096256 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1695 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/32 (20160201) A61B 90/10 (20160201) A61B 2017/00026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821195 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Jason S. Lewis (New York, New York); Melissa Deri (Hottsville, New York); Lynn Francesconi (Bridgewater, New Jersey); Shashikanth Ponnala (Secaucus, New Jersey) |
| ABSTRACT | Described herein is a chelator for radiolabels (e.g., 89Zr) for targeted PET imaging that is an alternative to DFO. In certain embodiments, the chelator for 89Zr is the ligand, 3,4,3-(LI-1,2-HOPO) (“HOPO”), which exhibits equal or superior stability compared to DFO in chemical and biological assays across a period of several days in vivo. As shown in FIG. 1, the HOPO is an octadentate chelator that stabilizes chelation of radiolabels (e.g., 89Zr). A bifunctional ligand comprising p-SCN-Bn-HOPO is shown in FIG. 4 and FIG. 5. Such a bifunctional ligand can eliminate (e.g., 89Zr) loss from the chelate in vivo and reduce uptake in bone and non-target tissue. Therefore, the bifunctional HOPO ligand can facilitate safer and improved PET imaging with radiolabeled antibodies. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/759154 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class A61K 51/1051 (20130101) A61K 51/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821204 | Grinstaff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Mark Grinstaff (Brookline, Massachusetts); Benjamin Goldman Cooper (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides polymers which can be used as tissue supplements or lubricants in vivo. The inventive polymers can be used as tissue-interpenetrating hydrogel supplements, viscosupplements, tribosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and injured synovial joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery or malfunction of naturally lubricious mucosal tissue. |
| FILED | Wednesday, December 13, 2017 |
| APPL NO | 15/840302 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2400/06 (20130101) A61L 2400/10 (20130101) A61L 2430/06 (20130101) A61L 2430/34 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/28 (20130101) C08F 220/387 (20200201) C08F 222/102 (20200201) C08F 222/102 (20200201) C08F 230/02 (20130101) C08F 230/02 (20130101) C08F 230/02 (20130101) Compositions of Macromolecular Compounds C08L 43/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821441 | Vanapalli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech Univeristy System (Lubbock, Texas) |
| INVENTOR(S) | Siva A. Vanapalli (Lubbock, Texas); Swastika S. Bithi (Lubbock, Texas) |
| ABSTRACT | A microfluidic device includes a substrate and a cover. The substrate has an inlet port, a first microchannel, one or more parking loops, a second microchannel and an outlet port for each microchannel network. The first microchannel is connected to the inlet port, the second microchannel is connected to the outlet port, the parking loops are connected between the first and second microchannels. Each parking loop includes a parking loop inlet, a parking loop output, a fluidic trap connected between the parking loop inlet and the parking loop outlet, and a bypass microchannel connected to the parking loop inlet and the parking loop outlet. The cover is attached to a top of the substrate and has an inlet opening and an outlet opening through the cover for each microchannel network. The inlet and outlet openings of the cover are disposed above the inlet and outlet ports in the substrate. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/580439 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/142 (20130101) B01L 2300/041 (20130101) B01L 2300/087 (20130101) B01L 2300/088 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2400/049 (20130101) B01L 2400/084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10821565 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Chao Liu (Heilongjiang Province, China PRC); Jeong-Hyun Cho (Woodbury, Minnesota) |
| ABSTRACT | Methods of manufacturing a 3D micro-scale structure. A 2D net including a plurality of panels and a plurality of hinges is provided. The panels are arranged in a pattern. The hinges interconnect immediately adjacent ones of the panels within the pattern. An energy source remote from the 2D net is powered to deliver energy to the 2D net. The delivered energy triggers the 2D net to self-fold into a 3D micro-scale structure. The delivered energy creates an eddy current within at least one component of the 2D net, with the eddy current generating heat sufficient to melt at least one of the hinges. The melting hinge causes the corresponding panels to fold or pivot relative to one another. In some embodiments, the energy source is a microwave energy source. In other embodiments, the energy source delivers a magnetic field. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997049 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Original (OR) Class Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/00 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00007 (20130101) B81C 1/00134 (20130101) B81C 2201/0163 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/90 (20130101) Y10S 977/882 (20130101) Y10S 977/901 (20130101) Y10S 977/904 (20130101) Y10S 977/906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822240 | Pegna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FREE FORM FIBERS, LLC (Saratoga Springs, New York) |
| ASSIGNEE(S) | FREE FORM FIBERS, LLC (Saratoga Springs, New York) |
| INVENTOR(S) | Joseph Pegna (Saratoga Springs, New York); John L. Schneiter (Cohoes, New York); Kirk L. Williams (Saratoga Springs, New York); Ramkiran Goduguchinta (Ballston Lake, New York) |
| ABSTRACT | A method and apparatus for forming a plurality of fibers from (e.g., CVD) precursors, including a reactor adapted to grow a plurality of individual fibers; and a plurality of independently controllable lasers, each laser of the plurality of lasers growing a respective fiber. A high performance fiber (HPF) structure, including a plurality of fibers arranged in the structure; a matrix disposed between the fibers; wherein a multilayer coating is provided along the surfaces of at least some of the fibers with an inner layer region having a sheet-like strength; and an outer layer region, having a particle-like strength, such that any cracks propagating toward the outer layer from the matrix propagate along the outer layer and back into the matrix, thereby preventing the cracks from approaching the fibers. A method of forming an interphase in a ceramic matrix composite material having a plurality of SiC fibers, which maximizes toughness by minimizing fiber to fiber bridging, including arranging a plurality of SiC fibers into a preform; selectively removing (e.g., etching) silicon out of the surface of the fibers resulting in a porous carbon layer on the fibers; and replacing the porous carbon layer with an interphase layer (e.g., Boron Nitride), which coats the fibers to thereby minimize fiber to fiber bridging in the preform. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/101730 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/956 (20170801) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/76 (20130101) C04B 35/565 (20130101) C04B 35/806 (20130101) C04B 35/62865 (20130101) C04B 35/62868 (20130101) C04B 35/62873 (20130101) C04B 2235/616 (20130101) C04B 2235/3409 (20130101) C04B 2235/5244 (20130101) C04B 2235/5264 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/08 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249964 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822448 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Kaimin Cai (Champaign, Illinois); Hanze Ying (Champaign, Illinois) |
| ABSTRACT | The present invention relates to polymers having dynamic urea bonds and more specifically to polymers having hindered urea bonds (HUBs) with fast hydrolytic kinetics. These urea bonds are aryl-substituted, i.e. aromatic-substituted hindered urea bonds, that demonstrate pH independent hydrolytic kinetics, such that they consistently and rapidly hydrolyze in water from pH 2 to 11. The urea bond dissociation for these materials is generally such that k−1>h−1, which is two orders of magnitudes faster than for aliphatic hindered ureas. The present invention also relates to hydrolytically reversible or degradable linear, branched or network polymers incorporating these HUBs and to precursors for incorporation of these HUBs into these polymers. The technology can be applied to and integrated into a variety of polymers, such as polyureas, polyurethanes, polyesters, polyamides, polycarbonates, polyamines, and polysaccharides to make linear, branched, and cross-linked polymers. Polymers incorporating these HUBs can be used in a wide variety of applications including for example, environmentally compatible packaging materials and biomedical applications, such as drug delivery systems and tissue engineering. In other embodiments, the HUBs can be used in self-healing polymers. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 16/082969 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/10 (20130101) A61L 27/18 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 65/466 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/325 (20130101) C08G 18/3228 (20130101) C08G 18/4825 (20130101) C08G 18/6685 (20130101) C08G 18/7671 (20130101) Original (OR) Class C08G 2220/00 (20130101) C08G 2230/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2375/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822466 | Leventis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aerogel Technologies, LLC (Glendale, Wisconsin) |
| ASSIGNEE(S) | Aerogel Technologies, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Nicholas Leventis (Rolla, Missouri); Chariklia Sotiriou-Leventis (Rolla, Missouri); Chakkaravarthy Chidambareswarapattar (Rolla, Missouri) |
| ABSTRACT | Nanoporous three-dimensional networks of polyurethane particles, e.g., polyurethane aerogels, and methods of preparation are presented herein. Such nanoporous networks may include polyurethane particles made up of linked polyisocyanate and polyol monomers. In some cases, greater than about 95% of the linkages between the polyisocyanate monomers and the polyol monomers are urethane linkages. To prepare such networks, a mixture including polyisocyanate monomers (e.g., diisocyanates, triisocyanates), polyol monomers (diols, triols), and a solvent is provided. The polyisocyanate and polyol monomers may be aliphatic or aromatic. A polyurethane catalyst is added to the mixture causing formation of linkages between the polyisocyanate monomers and the polyol monomers. Phase separation of particles from the reaction medium can be controlled to enable formation of polyurethane networks with desirable nanomorphologies, specific surface area, and mechanical properties. Various properties of such networks of polyurethane particles (e.g., strength, stiffness, flexibility, thermal conductivity) may be tailored depending on which monomers are provided in the reaction. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/220091 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) B01J 20/267 (20130101) B01J 20/3078 (20130101) B01J 20/28011 (20130101) B01J 20/28042 (20130101) B01J 20/28047 (20130101) B01J 20/28057 (20130101) B01J 20/28078 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) C01B 32/05 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/06 (20130101) C08G 18/792 (20130101) C08G 18/3215 (20130101) C08G 18/3872 (20130101) C08G 18/7657 (20130101) C08G 18/7664 (20130101) C08G 18/7893 (20130101) C08G 2101/0091 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/286 (20130101) Original (OR) Class C08J 2201/04 (20130101) C08J 2201/0502 (20130101) C08J 2205/026 (20130101) C08J 2205/042 (20130101) C08J 2375/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/21 (20150115) Y10T 428/1376 (20150115) Y10T 428/2982 (20150115) Y10T 428/24149 (20150115) Y10T 428/31547 (20150401) Y10T 428/249953 (20150401) Y10T 428/249978 (20150401) Y10T 428/249986 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822467 | Yue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Liang Yue (Cleveland, Ohio); Vahab Solouki Bonab (Cleveland, Ohio); Ammar Patel (Cleveland, Ohio); Dian Yuan (Cleveland, Ohio); Vahid Karimkhani (Chapel Hill, North Carolina); Ica Manas-Zloczower (Pepper Pike, Ohio) |
| ABSTRACT | Methods for recycling thermoset polymers, particularly by changing them into dynamic networks with the use of an appropriate catalyst solution which transforms the thermoset polymer into a vitrimer-like composition. The methods include the step of swelling a crosslinked thermoset polymer in a solution including a catalyst, whereby the catalyst diffuses into the thermoset polymer, in particular into the thermoset network. Upon removal of the liquid portion of the solution, such as solvent, the catalyst facilitates the occurrence of exchange reactions at elevated temperatures, rendering the system a dynamic network. The vitrimerized composition having the thermoset polymer and catalyst is recyclable and processable and thus suitable for many end uses. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964824 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/122 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/203 (20130101) C08J 3/2053 (20130101) C08J 11/04 (20130101) Original (OR) Class C08J 11/16 (20130101) C08J 2300/24 (20130101) C08J 2363/02 (20130101) C08J 2375/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 3/041 (20170501) C08K 3/041 (20170501) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822670 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim Karaman (College Stationi, Texas); Raymundo Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/217594 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) B23K 2101/16 (20180801) B23K 2103/04 (20180801) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) F27D 2007/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822689 | Shih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Wei-Chuan Shih (Houston, Texas); Fusheng Zhao (Houston, Texas); Jingting Li (Houston, Texas) |
| ABSTRACT | A nanoporous metal can be formed by projecting laser patterns using a spatial light modulator (SLM) onto a gold/silver alloy film immersed in diluted nitric acid solutions. Heat accumulation induced by the photothermal effect enables localized dealloying in dilute nitric acid. NPG micropatterns can be formed at the irradiated spots while the surrounding alloy remains intact. |
| FILED | Friday, September 15, 2017 |
| APPL NO | 16/333695 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) Original (OR) Class C23C 14/56 (20130101) C23C 14/586 (20130101) C23C 14/5813 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822793 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VERCO DECKING INC. (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cheng Yu (Southlake, Texas); Jeffrey Reino Martin (Fremont, California); Richard B. Haws (Corinth, Texas) |
| ABSTRACT | Embodiments of the invention relate to structural panel systems, and in particular in-frame fluted panel systems. The in-frame fluted panel systems allow for improved strength and/or ductility within a reduced wall thickness by installing the fluted panels within the framing of the support members in various configurations. The in-frame fluted panel systems further allows for easier construction and lower costs than conventional systems that have fluted panels located outside of the support members. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/466983 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/08 (20130101) E04B 2/56 (20130101) Original (OR) Class Structural Elements; Building Materials E04C 2/322 (20130101) E04C 2/384 (20130101) Roof Coverings; Sky-lights; Gutters; Roof-working Tools E04D 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823630 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Liang Dong (Ames, Iowa); Qiugu Wang (Ames, Iowa); Wei Hong (Ames, Iowa) |
| ABSTRACT | We present a microelectromechanical system (MEMS) graphene-based pressure sensor realized by transferring a large area, few-layered graphene on a suspended silicon nitride thin membrane perforated by a periodic array of micro-through-holes. Each through-hole is covered by a circular drum-like graphene layer, namely a graphene “microdrum”. The uniqueness of the sensor design is the fact that introducing the through-hole arrays into the supporting nitride membrane allows generating an increased strain in the graphene membrane over the through-hole array by local deformations of the holes under an applied differential pressure. Further reasons contributing to the increased strain in the devised sensitive membrane include larger deflection of the membrane than that of its imperforated counterpart membrane, and direct bulging of the graphene microdrum under an applied pressure. Electromechanical measurements show a gauge factor of 4.4 for the graphene membrane and a sensitivity of 2.8×10-5 mbar-1 for the pressure sensor specific example described, with a good linearity over a wide pressure range. The present sensor outperforms most existing MEMS-based small footprint pressure sensors using graphene, silicon, and carbon nanotubes as sensitive materials, due to the high sensitivity. |
| FILED | Monday, November 13, 2017 |
| APPL NO | 15/811154 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0047 (20130101) G01L 9/0054 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823649 | Westerhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona); Treavor Boyer (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Shahnawaz Sinha (Chandler, Arizona); Treavor Boyer (Scottsdale, Arizona) |
| ABSTRACT | A microfluidic device includes a sample inlet for a fluid sample, a degassing chamber having a gas-permeable membrane and defining first and second portions separated by the gas permeable membrane, and a detection chamber. The sample inlet and the detection chamber are fluidly coupled to the first and second portions, respectively of the degassing chamber. The detection chamber is operably coupled to a light source and a detector. Assessing a concentration of chlorine gas in an aqueous sample includes providing an aqueous sample to a microfluidic device, separating gas from the aqueous sample in the microfluidic device, providing the gas to a detector, assessing the absorbance of the gas sample at a known absorption wavelength of chlorine, and based on the assessed absorbance of the gas sample at the known absorption wavelength of chlorine, assessing a concentration of chlorine gas in the aqueous sample. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/146160 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Separation B01D 19/0031 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0654 (20130101) B01L 2300/0663 (20130101) B01L 2300/0816 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/4005 (20130101) Original (OR) Class G01N 21/05 (20130101) G01N 21/31 (20130101) G01N 21/255 (20130101) G01N 21/3103 (20130101) G01N 33/18 (20130101) G01N 2001/2267 (20130101) G01N 2021/054 (20130101) G01N 2021/0346 (20130101) G01N 2201/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823667 | Ramachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Siddharth Ramachandran (Boston, Massachusetts); Gautam Prabhakar (Boston, Massachusetts); Aaron G. Peterson-Greenberg (Cambridge, Massachusetts) |
| ABSTRACT | A system comprises an electromagnetic radiation source, a polarizing element, a mode converter, an optical fiber, and a measurement device. The polarizing element receives electromagnetic radiation produced by the electromagnetic radiation source and outputs linearly-polarized electromagnetic radiation having a linear polarization angle θ1. The mode converter converts the linearly-polarized electromagnetic radiation to an orbital angular momentum (OAM) mode of linearly-polarized electromagnetic radiation with topological charge Li. The OAM mode of linearly-polarized electromagnetic radiation is a superposition of first and second OAM modes with topological charges Li and opposite circular polarizations. The optical fiber supports propagation of the first and second OAM modes with an absolute effective index difference Δneff greater than or equal to 5×10−5, such that linearly-polarized electromagnetic radiation with linear polarization angle θ2 is emitted by the optical fiber. The measurement device is configured to determine a property of the electromagnetic radiation based on the polarization angle θ2. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/866391 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/21 (20130101) G01N 21/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823723 | Khismatullin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Administrators of the Tulane Education Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | The Administration of the Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | Damir Khismatullin (New Orleans, Louisiana); Daishen Luo (Metairie, Louisiana) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to ATPA technology that provides a method for the real-time assessment of the polymerization of a sample, e.g., whole blood or blood plasma coagulation, by a non-contact acoustic tweezing device. The acoustic tweezing technology integrates photo-optical tests used in plasma coagulation assays with mechanical (viscoelastic) tests used in whole blood analysis. Its key disruptive features are the increased reliability and accuracy due to non-contact measurement, low sample volume requirement, relatively short procedure time (less than 10 minutes), and the ability to assess the level of Factor XIII function from measurements of the fibrin network formation time. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 16/478249 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/82 (20130101) G01N 21/272 (20130101) G01N 33/86 (20130101) G01N 33/4905 (20130101) Original (OR) Class G01N 2021/1721 (20130101) G01N 2021/1725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824045 | Rumpf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION (Orlando, Florida); THE UNIVERSITY OF TEXAS AT EL PASO (Austin, Texas) |
| INVENTOR(S) | Raymond C. Rumpf (El Paso, Texas); Stephen Kuebler (Orlando, Florida); Noel P. Martinez (El Paso, Texas); Cesar Luis Valle (El Paso, Texas) |
| ABSTRACT | Embodiments of the invention are directed compositions and devices that include a spatially-variant lattice (SVL), such as spatially variant photonic crystals (SVPC), as well as methods for making and using the same. In particular, the compositions and devices include SVPCs that are configured for manipulating the path and/or properties of electromagnetic radiation flowing through the SVPC in a variety of ways. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/627060 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/293 (20130101) Original (OR) Class G02F 2201/38 (20130101) G02F 2202/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824818 | Peper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Joseph Peper (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Sean Stapleton (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Jason Mars (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for synthesizing training data for multi-intent utterance segmentation include identifying a first corpus of utterances comprising a plurality of distinct single-intent in-domain utterances; identifying a second corpus of utterances comprising a plurality of distinct single-intent out-of-domain utterances; identifying a third corpus comprising a plurality of distinct conjunction terms; forming a multi-intent training corpus comprising synthetic multi-intent utterances, wherein forming each distinct multi-intent utterance includes: selecting a first distinct in-domain utterance from the first corpus of utterances; probabilistically selecting one of a first out-of-domain utterance from the second corpus and a second in-domain utterance from the first corpus; probabilistically selecting or not selecting a distinct conjunction term from the third corpus; and forming a synthetic multi-intent utterance including appending the first in-domain utterance with one of the first out-of-domain utterance from the second corpus of utterances and the second in-domain utterance from the first corpus of utterances. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854834 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) Original (OR) Class G06F 40/284 (20200101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/063 (20130101) G10L 15/1815 (20130101) G10L 15/1822 (20130101) G10L 2015/0633 (20130101) G10L 2015/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827349 | Bang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Jae Young Bang (Los Angeles, California); Youn Kyu Lee (Los Angeles, California); Nenad Medvidovic (Los Angeles, California); Daye Nam (Los Angeles, California); Gholamreza Safi (Los Angeles, California); Arman Shahbazian (Los Angeles, California); Peera Yoodee (Los Angeles, California); Yixue Zhao (Los Angeles, California) |
| ABSTRACT | A system for providing increased security in a mobile operating system includes at least one mobile device and a remote computing device that is remote from the mobile device. The remote computing device receives a list of two or more applications that are currently installed or intended to be installed on the mobile device's operating system. The remote computing device identifies vulnerable inter-component communication (ICC) paths by analyzing files associated with each of the two or more applications. A list of the vulnerable ICC paths is stored in memory of the mobile device. The mobile processor compares the list of the vulnerable ICC paths to intents sent by the components of the two or more applications and identifies a potential unsecure intent that matches one of the list of the vulnerable ICC paths. Unsecured intents can then be blocked by the user. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/410347 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) G06F 2221/033 (20130101) Wireless Communication Networks H04W 12/0023 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827503 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Junshan Zhang (Tempe, Arizona); Xu Chen (Tempe, Arizona); Zhengyu Zhang (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Junshan Zhang (Tempe, Arizona); Xu Chen (Tempe, Arizona); Zhengyu Zhang (Tempe, Arizona) |
| ABSTRACT | A plurality of mobile devices is provided including a first mobile device of the plurality of mobile devices that serves as a relay for communication between a second mobile device of the plurality of mobile devices and a third mobile device of the plurality of mobile devices. The first mobile device is identified as the relay based on a social trust relationship formed between the first mobile device and the second mobile device. A D2D network is formed between the first mobile device and second mobile device. A communication channel is provided to the second mobile device from a second cellular network. A portion of the communication channel is allocated to the second mobile device using the D2D network to improve cellular transmission between the second mobile device and the third mobile device. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170937 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Wireless Communication Networks H04W 4/21 (20180201) H04W 8/005 (20130101) H04W 40/22 (20130101) H04W 48/16 (20130101) H04W 72/048 (20130101) Original (OR) Class H04W 72/0453 (20130101) H04W 76/14 (20180201) H04W 88/04 (20130101) H04W 88/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10822240 | Pegna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FREE FORM FIBERS, LLC (Saratoga Springs, New York) |
| ASSIGNEE(S) | FREE FORM FIBERS, LLC (Saratoga Springs, New York) |
| INVENTOR(S) | Joseph Pegna (Saratoga Springs, New York); John L. Schneiter (Cohoes, New York); Kirk L. Williams (Saratoga Springs, New York); Ramkiran Goduguchinta (Ballston Lake, New York) |
| ABSTRACT | A method and apparatus for forming a plurality of fibers from (e.g., CVD) precursors, including a reactor adapted to grow a plurality of individual fibers; and a plurality of independently controllable lasers, each laser of the plurality of lasers growing a respective fiber. A high performance fiber (HPF) structure, including a plurality of fibers arranged in the structure; a matrix disposed between the fibers; wherein a multilayer coating is provided along the surfaces of at least some of the fibers with an inner layer region having a sheet-like strength; and an outer layer region, having a particle-like strength, such that any cracks propagating toward the outer layer from the matrix propagate along the outer layer and back into the matrix, thereby preventing the cracks from approaching the fibers. A method of forming an interphase in a ceramic matrix composite material having a plurality of SiC fibers, which maximizes toughness by minimizing fiber to fiber bridging, including arranging a plurality of SiC fibers into a preform; selectively removing (e.g., etching) silicon out of the surface of the fibers resulting in a porous carbon layer on the fibers; and replacing the porous carbon layer with an interphase layer (e.g., Boron Nitride), which coats the fibers to thereby minimize fiber to fiber bridging in the preform. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/101730 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/956 (20170801) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/76 (20130101) C04B 35/565 (20130101) C04B 35/806 (20130101) C04B 35/62865 (20130101) C04B 35/62868 (20130101) C04B 35/62873 (20130101) C04B 2235/616 (20130101) C04B 2235/3409 (20130101) C04B 2235/5244 (20130101) C04B 2235/5264 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/08 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249964 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822689 | Shih et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Wei-Chuan Shih (Houston, Texas); Fusheng Zhao (Houston, Texas); Jingting Li (Houston, Texas) |
| ABSTRACT | A nanoporous metal can be formed by projecting laser patterns using a spatial light modulator (SLM) onto a gold/silver alloy film immersed in diluted nitric acid solutions. Heat accumulation induced by the photothermal effect enables localized dealloying in dilute nitric acid. NPG micropatterns can be formed at the irradiated spots while the surrounding alloy remains intact. |
| FILED | Friday, September 15, 2017 |
| APPL NO | 16/333695 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) Original (OR) Class C23C 14/56 (20130101) C23C 14/586 (20130101) C23C 14/5813 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823398 | Choudhri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ahsan R. Choudhri (El Paso, Texas); Norman D. Love, Jr. (El Paso, Texas); Luis E. Sanchez (Sunland Park, New Mexico); Charles S. Hill (Las Cruces, New Mexico) |
| ABSTRACT | A torch igniter and a method of igniting a torch flame. An example embodiment includes a body including an oxidizer inlet configured to facilitate oxidizer flow through the body toward an output end of the body. The body includes a group of fuel inlet passages configured to distribute fuel in a direction tangential to the oxidizer flow through the body to create a swirling fuel-oxidizer mixture. A sparking element can be mounted on the body to produce a spark in the path of the swirling fuel-oxidizer mixture to ignite the mixture. The output end of the body is configured to emit a torch flame when the fuel-oxidizer mixture is ignited. Thus, a swirl torch igniter is configured for oxidizer and fuel flow through the igniter body to create an internal swirling fuel-oxidizer mixture to be ignited by a sparking element. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609898 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/264 (20130101) Jet-propulsion Plants F02K 9/95 (20130101) Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines F02P 15/001 (20130101) Burners F23D 11/103 (20130101) Original (OR) Class F23D 14/02 (20130101) F23D 2207/00 (20130101) Ignition; Extinguishing-devices F23Q 3/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825182 | Le Moigne-Stewart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jacqueline J. Le Moigne-Stewart (Greenbelt, Maryland); David Solarna (Genoa, Italy); Gabriele Moser (Genoa, Italy); Sebastiano Serpico (Genoa, Italy); Alberto Gotelli (Genoa, Italy) |
| ABSTRACT | The present invention relates to a novel method and system for crater detection in planetary data based on marked point processes (MPP), effective for various object detection tasks in Earth observation, and for planetary image registration. The resulting spatial features are exploited for registration, together with fitness functions based on the MPP energy, on the mean directed Hausdorff distance, and on the mutual information. Two different methods—one based on birth-death processes and region-of-interest analysis, and the other based on graph cuts and decimated wavelets—are included within the present framework. Experimental results confirmed the effectiveness of the present invention in terms of crater detection performance and sub-pixel registration accuracy. |
| FILED | Wednesday, September 12, 2018 |
| APPL NO | 16/128840 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/20 (20130101) G06T 7/11 (20170101) G06T 7/13 (20170101) Original (OR) Class G06T 7/37 (20170101) G06T 7/337 (20170101) G06T 2207/10032 (20130101) G06T 2207/20016 (20130101) G06T 2207/20132 (20130101) G06T 2207/30181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826609 | Cahoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kerri Cahoy (Lexington, Massachusetts); Christian Haughwout (Clinton, Connecticut); James Clark (Cambridge, Massachusetts); Paula do Vale Pereira (Arlington, Massachusetts) |
| ABSTRACT | A beam steering system for a free-space laser communication system in a satellite includes a laser that emits a laser beam, a liquid lens assembly with at least one liquid lens to change the direction of the laser beam, and an amplifying optic to amplify the change in direction of the laser beam. The beam steering system may be used to steer a laser beam transmitted to another satellite or received from another satellite. In one example, a satellite may include two beam steering systems, disposed at opposing ends of a frame, where each steering system is configured to cover a hemisphere such that together, the steering systems can transmit and/or receive a laser beam over a 4π steradian sphere. The beam steering system may include a transmit feedback system and a reception system to monitor the direction and signal of the transmitted beam and the received beam, respectively. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447648 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) B64G 1/1007 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/29 (20130101) G02F 2001/294 (20130101) G02F 2203/24 (20130101) Transmission H04B 10/118 (20130101) Original (OR) Class H04B 10/503 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10820850 | Publicover et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Google LLC (Mountain View, California) |
| ASSIGNEE(S) | Google LLC (Mountain View, California) |
| INVENTOR(S) | Nelson G. Publicover (Reno, Nevada); William C. Torch (Reno, Nevada) |
| ABSTRACT | Systems and methods are provided to measure reaction times and/or responses for head, eye, eyelid movements, and/or changes in pupil geometry. The system includes eyewear or headwear including one or more eye-tracking cameras for monitoring the position and geometry of at least one eye and its components of the user, one or more scene cameras for monitoring the user's surroundings, and one or more processors to determine reaction times. Optionally, the system may include one or more of a multi-axis accelerometer to monitor head movements, light sources to trigger visual evoked responses, and/or electronic inputs that may be used to indicate the time of occurrence of external reference events. Measured reaction times and other measurements may be monitored for use in a range of applications. Responses and reaction times may be measured continuously over extended periods, even over a lifetime to measure consequences of the aging process. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897580 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/112 (20130101) A61B 3/113 (20130101) A61B 5/162 (20130101) Original (OR) Class A61B 5/1103 (20130101) A61B 5/1114 (20130101) A61B 5/6803 (20130101) A61B 2560/0242 (20130101) A61B 2562/0204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822959 | Molony et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Evan P. Molony (Farmington, Connecticut); Carey Clum (East Hartford, Connecticut); Dominic J. Mongillo (West Hartford, Connecticut); Charles Thistle (Middletown, Connecticut) |
| ABSTRACT | A casting core may include a core body and a tip comb extending from a tip region of the core body. The tip comb may be integrally formed with the core body. The tip comb may comprise a first casting pedestal and a second casting pedestal. The first casting pedestal and the second casting pedestal may define an aperture having a tapered geometry. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623787 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Foundry Moulding B22C 9/10 (20130101) B22C 9/24 (20130101) B22C 13/085 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 29/001 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/388 (20130101) F04D 29/582 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2260/20 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823059 | Herman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | David Michael Herman (Beavercreek, Ohio); Wendy Wenling Lin (Montgomery, Ohio) |
| ABSTRACT | Acoustic core segments include splicing resonant cells that resemble a first segment of a whole resonant cell configured to overlap and align with counterpart splicing resonant cells of another acoustic core segment so as to define a splice joint. The splicing resonant cells include one or more fastening elements configured to couple with corresponding counterpart splicing resonant cells thereby together defining coupled resonant cells. Acoustic liners have an acoustic core assembly that includes a first acoustic core segment mechanically joined with a second acoustic core segment by a combination of splicing resonant cells of the first acoustic core segment overlapping and aligning with splicing resonant cells of the second acoustic core segment so as to define a splice joint, and a plurality of fastening elements coupling splicing resonant cells of the first acoustic core segment with splicing resonant cells of the second acoustic core segment. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/150448 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 2307/102 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/045 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/827 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/51 (20130101) F05D 2240/14 (20130101) F05D 2260/30 (20130101) F05D 2260/96 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826270 | Treese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Automotive Coalition for Traffic Safety, Inc. (Washington, District of Columbia) |
| ASSIGNEE(S) | Automotive Coalition for Traffic Safety, Inc. (Washington, District of Columbia) |
| INVENTOR(S) | Derek Treese (Tustin, California); Nicolas Koslowski (Würzburg, Germany); Michael Legge (Würzburg, Germany); Wolfgang Zeller (Würzburg, Germany) |
| ABSTRACT | Systems and methods are described herein to thermally regulate laser diodes. During operation, the structure of a laser diode may generate heat, which will affect the stability and accuracy of the output wavelength of the laser diode. During an OFF stage, the structure of the laser diode will then lose heat, creating a thermal gradient as the laser diode is switched between operation and an OFF state. The systems and methods provide constant average heat and a stable thermal gradient by integrating a laser diode power-coupled supply and a heater onto a heatspreader, such that the output wavelength of a coupled laser diode may be stabilized. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/343513 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0612 (20130101) Original (OR) Class H01S 5/02415 (20130101) H01S 5/02453 (20130101) H01S 5/02476 (20130101) H01S 5/4025 (20130101) H01S 5/4087 (20130101) H01S 5/06804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10821160 | Lavie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Arnon Lavie (Chicago, Illinois); Hien-Anh Nguyen (Chicago, Illinois) |
| ABSTRACT | Variant Erwinia chrysanthemi L-asparaginases with reduced L-glutaminase activity and enhanced in vivo circulation are described as are fusion proteins containing an L-asparaginase and three tandem soluble domains of TRAIL for use in the treatment of cancers such as acute lymphoblastic leukemia and acute myeloid leukemia. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 16/080435 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/50 (20130101) Original (OR) Class A61K 47/65 (20170801) A61K 47/67 (20170801) A61K 47/6815 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/52 (20130101) C07K 2319/35 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/82 (20130101) C12N 15/52 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/18 (20130101) Enzymes C12Y 305/01001 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824825 | Jinedatha |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Department of Vetrans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Chetan Jinedatha (Temple, Texas) |
| ABSTRACT | The invention provides method for organizing the disinfection of one or more items contaminated with biological agent(s) comprising (a) attaching a radio-frequency ID (RFID) tag to an item(s) to be disinfected; exposing the item(s) of (a) to a disinfecting means for a period sufficient to disinfect the item; and (c) obtaining a signal from the tagged item when disinfection is complete thereby organizing the disinfection of one or more items. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289539 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/24 (20130101) A61L 2/208 (20130101) A61L 2202/14 (20130101) A61L 2202/25 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10118 (20130101) Original (OR) Class G06K 7/10415 (20130101) G06K 7/10475 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) Technologies for Adaptation to Climate Change Y02A 90/22 (20180101) Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10823687 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | UHV Technologies, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, Jr. (Lexington, Kentucky) |
| ABSTRACT | A system and method for detecting, measuring, and analyzing for metallic impurities in pharmaceutical drugs and compounds utilizes an x-ray fluorescence system. The system and method may be co-located with a pharmaceutical manufacturing process for in-line continuous monitoring of metal impurities. The pharmaceutical products may be in a form selected from a powder, slurry, pill, tablet, and gel. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/227438 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) Original (OR) Class G01N 33/15 (20130101) G01N 2223/076 (20130101) G01N 2223/652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824818 | Peper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Joseph Peper (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Sean Stapleton (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Jason Mars (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for synthesizing training data for multi-intent utterance segmentation include identifying a first corpus of utterances comprising a plurality of distinct single-intent in-domain utterances; identifying a second corpus of utterances comprising a plurality of distinct single-intent out-of-domain utterances; identifying a third corpus comprising a plurality of distinct conjunction terms; forming a multi-intent training corpus comprising synthetic multi-intent utterances, wherein forming each distinct multi-intent utterance includes: selecting a first distinct in-domain utterance from the first corpus of utterances; probabilistically selecting one of a first out-of-domain utterance from the second corpus and a second in-domain utterance from the first corpus; probabilistically selecting or not selecting a distinct conjunction term from the third corpus; and forming a synthetic multi-intent utterance including appending the first in-domain utterance with one of the first out-of-domain utterance from the second corpus of utterances and the second in-domain utterance from the first corpus of utterances. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854834 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) Original (OR) Class G06F 40/284 (20200101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/063 (20130101) G10L 15/1815 (20130101) G10L 15/1822 (20130101) G10L 2015/0633 (20130101) G10L 2015/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10822185 | Stratton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Christopher M. Stratton (Springfield, Virginia); Gregory J. Smith (Arlington, Virginia); Thomas C. Potter (Oak Hill, Virginia); Wayne R. Perry-Eaton (Leesburg, Virginia) |
| ABSTRACT | Features for loading, transporting and unloading of items are disclosed. Systems, devices and methods for such operations using a tray are described. In some embodiments, a tray having a moveable bottom allows for switching between a configuration for loading and unloading items in and out of the tray and a configuration for transportation of items inside the tray. The trays may also be stacked, for transportation of multiple trays at once, and nested, for saving space when storing the trays. In some embodiments, the trays may be used in conjunction with loading and unloading systems. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406350 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 65/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825011 | Reblin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Gary C. Reblin (Falls Church, Virginia) |
| ABSTRACT | An interrogating and processing system and method is described. A wireless communication device interrogates an information source, having a barcode or tag, and wirelessly transmits data indicative of the information source. The interrogator can be built into or adjunct to the wireless communication device. An automated processing subsystem receives the transmitted data and identifies an item corresponding to the data. A fulfillment subsystem effects delivery of the item to a destination. There can be a coupon code scanning and processing system and method. A wireless computing device having an interrogator reads a coupon code. An automated processing subsystem receives the corresponding data and provides a benefit associated with the coupon. The benefit can be a discount on a product or service. Alternatively, at least a portion of the coupon including a code is displayed on a screen of the computing device for processing at a point of sale terminal. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/664681 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 19/06028 (20130101) G06K 19/07758 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) G06Q 10/087 (20130101) G06Q 20/208 (20130101) Original (OR) Class G06Q 20/327 (20130101) G06Q 20/3276 (20130101) G06Q 20/3278 (20130101) G06Q 30/02 (20130101) G06Q 30/06 (20130101) G06Q 30/0238 (20130101) G06Q 30/0253 (20130101) Registering the Receipt of Cash, Valuables, or Tokens G07G 1/009 (20130101) G07G 1/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10825119 | Maher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | David Maher (Washington, District of Columbia) |
| ABSTRACT | Mobile collection and vetting of user supplied information is described. The systems, techniques, devices, methods, and approaches described herein can be used to obtain, validate, and vet information, such as customs information, in a mobile environment. In embodiments, methods comprise receiving information input via a mobile device. The information is encapsulated by an intermediate to escort the information through a firewall to the database. In response to vetting the information to determine if it meets one or more criteria, the method involves creating a record associated with a unique identifier, information that bio-identifies a user, or an indication of a determination that results from the vetting. In this embodiment, the method includes generating an electronic receipt for communication to the mobile device, the electronic receipt including the unique identifier. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 16/776286 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/83 (20190101) G06F 16/2228 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 10825948 | Riley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael Riley (Los Lunas, New Mexico); Mark Stan (Albuquerque, New Mexico); Arthur Cornfeld (Sandy Springs, Georgia) |
| ABSTRACT | A solar cell comprising an epitaxial sequence of layers of semiconductor material forming a solar cell deposited using an MOCVD reactor; a metal layer disposed on top of the sequence of layers of semiconductor material, the metal layer including a top surface layer composed of gold or silver; a polymer film; depositing a first metallic adhesion layer disposed on the polymer film that has a coefficient of thermal expansion substantially different from that of the top surface layer on one surface of the polymer film; a second metallic adhesion layer deposited over the first metallic adhesion layer and having a different composition from the first metallic adhesion layer and having no chemical elements in common; and the second metallic adhesion layer of the polymer film being permanently bonded to the metal layer of the sequence of layers of semiconductor material by a thermocompressive diffusion bonding technique. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/239098 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/184 (20130101) Original (OR) Class H01L 31/02167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10822962 | Vu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Ky H. Vu (East Hartford, Connecticut); Adam P. Generale (Dobbs Ferry, New York) |
| ABSTRACT | A platform for an airfoil of a gas turbine engine having an axis extending from a front of the gas turbine engine to a rear of the gas turbine engine. The platform includes a leading edge configured to face towards the front of the gas turbine engine. The platform further includes a trailing edge opposite the leading edge. The platform further includes a radially outer surface that defines a pocket for receiving a cooling airflow. The platform further includes a cover coupled to the radially outer surface to at least partially enclose the pocket and defining a plurality of air inlet holes configured to port at least a portion of the cooling airflow into the pocket. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/144677 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/30 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 9/065 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2240/121 (20130101) F05D 2240/122 (20130101) F05D 2260/201 (20130101) F05D 2260/2212 (20130101) F05D 2260/22141 (20130101) F05D 2260/40311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822975 | Kline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Bradley P. Kline (Middletown, Connecticut); Farruqh Shahab (Rockville, Connecticut) |
| ABSTRACT | A vane system includes vane segments that each have a platform, a connector box, and at least one airfoil extending between the platform and the connector box. The connector box has a first circumferential side in the form of a male connector and a second circumferential side in the form of a female socket. The vane segments are connected together in a circumferential row with the male connector of each said vane segment being received in the female socket of the next vane segment in the circumferential row. A majority of the male connectors are of a first, common connector length, and at least one of the male connectors is of a second connector length that is different than the common connector length. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020079 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10822983 | DiFrancesco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORTATION (Farmington, Connecticut) |
| INVENTOR(S) | Michael L. DiFrancesco (Waterbury, Connecticut); Tara L. D'Ambruoso (Oxford, Connecticut) |
| ABSTRACT | A hydrostatic seal assembly includes a seal support, a seal shoe integral to the seal support and radially movable relative to the seal support. A plurality of seal teeth are located at a radially inboard surface of the seal shoe. The seal shoe is formed from a first material and the radially inboard surface is formed from a second material softer than the first material such that the radially inboard surface is abradable in the event of a rub between the radially inboard surface and an adjacent rotating component. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889551 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) F01D 11/08 (20130101) F01D 11/12 (20130101) F01D 11/025 (20130101) Original (OR) Class Pistons; Cylinders; Sealings F16J 15/44 (20130101) F16J 15/441 (20130101) F16J 15/442 (20130101) F16J 15/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10823011 | Kantany et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Nicholas W. Kantany (Manchester, Connecticut); David T. Feindel (Ellington, Connecticut); Nico M. Rappoli (Middletown, Connecticut) |
| ABSTRACT | A gas turbine engine turbine section has tie rod assemblies interconnecting an inner diameter structure and an outer casing. Each tie rod has: an inner diameter end; an outer diameter end; and an eyelet of an outer diameter spherical bearing formed at the outer diameter end. A first clevis carries a spherical ball of the bearing, a shank of said clevis extending to an outer diameter (OD) end. A tensioning bolt is mated to a threaded opening in said clevis OD end whereby tightening said bolt applies a tension to said rod. A radial span between a center of the outer diameter spherical bearing and an inner diameter surface of the outer casing is at least 50% greater than that between an outer diameter (OD) surface of the outer ring and the center. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 16/270102 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/26 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10824310 | Acharya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Girish Acharya (Redwood City, California); Rakesh Kumar (West Windsor, New Jersey); Supun Samarasekara (Princeton, New Jersey); Louise Yarnall (San Mateo, California); Michael John Wolverton (Mountain View, California); Zhiwei Zhu (Princeton, New Jersey); Ryan Villamil (Plainsboro, New Jersey); Vlad Branzoi (Lawrenceville, New Jersey); James F. Carpenter (Mountain View, California); Glenn A. Murray (Jamison, Pennsylvania) |
| ABSTRACT | A computing system for virtual personal assistance includes technologies to, among other things, correlate an external representation of an object with a real world view of the object, display virtual elements on the external representation of the object and/or display virtual elements on the real world view of the object, to provide virtual personal assistance in a multi-step activity or another activity that involves the observation or handling of an object and a reference document. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/313578 |
| ART UNIT | 2142 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04842 (20130101) Original (OR) Class G06F 9/453 (20180201) Image Data Processing or Generation, in General G06T 11/00 (20130101) G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10825752 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Lei Jiang (Aloha, Oregon); Edwin B. Ramayya (Hillsboro, Oregon); Daniel Pantuso (Portland, Oregon); Rafael Rios (Austin, Texas); Kelin J. Kuhn (Aloha, Oregon); Seiyon Kim (Portland, Oregon) |
| ABSTRACT | Embodiments of the present disclosure describe techniques and configurations for integrated thermoelectric cooling. In one embodiment, a cooling assembly includes a semiconductor substrate, first circuitry disposed on the semiconductor substrate and configured to generate heat when in operation and second circuitry disposed on the semiconductor substrate and configured to remove the heat by thermoelectric cooling. Other embodiments may be described and/or claimed. |
| FILED | Tuesday, June 18, 2013 |
| APPL NO | 14/775487 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8238 (20130101) H01L 23/38 (20130101) Original (OR) Class H01L 27/092 (20130101) H01L 2224/16225 (20130101) H01L 2924/15311 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 2201/10166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10826686 | Cho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Chongwon Cho (Los Angeles, California); Chong Ding (Sunnyvale, California) |
| ABSTRACT | Described is a system for biometric based security. The system applies a reusable fuzzy vault (RFV) process to protect secret information. The RFV process comprises a locking algorithm and an unlocking algorithm. The locking algorithm takes as input a fuzzy string m generated from readings of biometrics and secret information sk to be protected, The locking algorithm outputs a public string vault and a hash value h of sk. The unlocking algorithm takes as input a public string vault and a fuzzy string m′, and outputs a string sk′ if fuzzy string m′ is sufficiently close to fuzzy string m. The unlocking algorithm further computes a hash value h′ of sk′ and compares it with h. The system allows access to the secret information sk when h′ is equivalent to h. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183161 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) Original (OR) Class H04L 2209/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10827139 | Tower et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | John Robertson Tower (Langhorne, Pennsylvania); Michael Raymond Piacentino (Robbinsville, New Jersey) |
| ABSTRACT | Systems, Methods, and Apparatuses for an image sensor and a control system to cooperate with each photodiode in individual pixels to allow multiple pixels in a set of pixels to operate in a different imaging-mode of operation simultaneously within multiple window regions of the image. The image sensor has multiple window regions each capable of operating in different operating modes. Each pixel contains multiple photodiodes. The imager is fabricated with an additional semiconductor layer containing one or more metallization layers for interconnections and providing active CMOS circuits for control. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375059 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14603 (20130101) H01L 27/14612 (20130101) H01L 27/14614 (20130101) H01L 27/14621 (20130101) H01L 27/14641 (20130101) H01L 27/14643 (20130101) Pictorial Communication, e.g Television H04N 5/355 (20130101) Original (OR) Class H04N 5/378 (20130101) H04N 5/3535 (20130101) H04N 5/3559 (20130101) H04N 5/3741 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 03, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201103.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page