FedInvent™ Patents

Patent Details for Tuesday, November 10, 2020

This page was updated on Monday, March 27, 2023 at 06:13 AM GMT

Department of Health and Human Services (HHS)

10827703 — Reduced gluten grains and compositions thereof

US 10827703	Moehs et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Arcadia Biosciences, Inc. (Davis, California)
ASSIGNEE(S)	ARCADIA BIOSCIENCES, INC. (Davis, California)
INVENTOR(S)	Charles Paul Moehs (Seattle, Washington); William J. Austill (Seattle, Washington); Dayna Loeffler (Seattle, Washington); Jessica Mullenberg (Seattle, Washington)
ABSTRACT	Plants with reduced gluten grains and compositions thereof are disclosed herein.
FILED	Monday, September 09, 2019
APPL NO	16/564636
ART UNIT	1662 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) A01H 6/4678 (20180501) Original (OR) Class
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10827911 — Optical imaging system employing vortex fiber for multiple-mode illumination

US 10827911	Ramachandran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
INVENTOR(S)	Siddharth Ramachandran (Boston, Massachusetts); Lu Yan (Sunnyvale, California); Poul Kristensen (Valby, Denmark)
ABSTRACT	A vortex optical fiber for use in an illumination subsystem of an optical imaging system (e.g., a stimulated emission depletion (STED) microscopy system) includes an elongated optically transmissive medium having a set of regions including a core region, a trench region surrounding the core region, a ring region surrounding the trench region, and a cladding region, the set of regions having a doping profile providing a Δn_efffor vector modes in an LP₁₁mode group of greater than 1×10⁻⁴in the visible spectral range so as to simultaneously guide stable Gaussian and orbital angular momentum (OAM) carrying modes at corresponding visible wavelengths.
FILED	Monday, June 05, 2017
APPL NO	16/306026
ART UNIT	2874 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0017 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/0286 (20130101) G02B 6/02071 (20130101) G02B 6/02195 (20130101) G02B 6/02366 (20130101) G02B 6/02395 (20130101) G02B 6/03644 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) G02B 27/58 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/094 (20130101)
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10827945 — Radiologically identified tumor habitats

US 10827945	Gillies et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S)	H. LEE. MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S)	Robert J. Gillies (Tampa, Florida); Robert A. Gatenby (Tampa, Florida); Natarajan Raghunand (Tampa, Florida); John Arrington (Tampa, Florida); Olya Stringfield (Tampa, Florida); Yoganand Balagurunathan (Tampa, Florida); Dmitry B. Goldgof (Lutz, Florida); Lawrence O. Hall (Tampa, Florida)
ABSTRACT	Virtually every cancer patient is imaged with CT, PET or MRI. Importantly, such imaging reveals that tumors are complex and heterogeneous, often containing multiple habitats within them. Disclosed herein are methods for analyzing these images to infer cellular and molecular structure in each of these habitats. The methods can involve spatially superimposing two or more radiological images of the tumor sufficient to define regional habitat variations in two or more ecological dynamics in the tumor, and comparing the habitat variations to one or more controls to predict the severity of the tumor.
FILED	Tuesday, March 10, 2015
APPL NO	15/124718
ART UNIT	2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0263 (20130101) A61B 5/7264 (20130101) A61B 5/14539 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) G01R 33/5602 (20130101) G01R 33/56341 (20130101)
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10827974 — Predicting weight loss and fat metabolism using optical signal changes in fat

US 10827974	Warren et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Robert Warren (Irvine, California); Goutham Ganesan (Irvine, California); Thomas O'Sullivan (Laguna Hills, California); Shaista Malik (Orange, California); Bruce J. Tromberg (Irvine, California); Pietro Galassetti (Washington, District of Columbia)
ABSTRACT	A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (μ_aand μ_s′) at each wavelength are calculated. The obtained μ_aand μ_s′ values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.
FILED	Friday, January 20, 2017
APPL NO	15/411674
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/743 (20130101) A61B 5/4872 (20130101) Original (OR) Class A61B 5/4875 (20130101) A61B 5/6823 (20130101) A61B 5/7275 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101)
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10827976 — Pressure modulation, motion detection, individualized geometry, and improved optic-skin coupling to improve long term clinical monitoring with diffuse optics

US 10827976	Busch, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S)	David R. Busch, Jr. (Philadelphia, Pennsylvania); Ashwin B. Parthasarathy (West Chester, Pennsylvania); Wesley B. Baker (Philadelphia, Pennsylvania); Malavika Chandra (Framingham, Massachusetts); Rickson C. Mesquita (Campinas, Brazil); Daniel J. Licht (Wallingford, Pennsylvania); Arjun G. Yodh (Merion, Pennsylvania); Kenneth Abramson (Ardmore, Pennsylvania)
ABSTRACT	The present disclosure provides devices and methods for improved hemodynamic monitoring, including devices for characterizing hemodynamic activity within a tissue or region of interest.
FILED	Tuesday, February 24, 2015
APPL NO	15/120895
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0261 (20130101) A61B 5/0295 (20130101) A61B 5/1495 (20130101) A61B 5/6814 (20130101) A61B 5/6843 (20130101) Original (OR) Class A61B 5/7246 (20130101) A61B 5/7282 (20130101) A61B 5/14552 (20130101) A61B 5/14553 (20130101) A61B 2560/0223 (20130101) A61B 2562/146 (20130101) A61B 2562/0238 (20130101) A61B 2562/0242 (20130101)
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10827983 — System and method for personalized cardiac arrhythmia risk assessment by simulating arrhythmia inducibility

US 10827983	Vadakkumpadan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Fijoy Vadakkumpadan (Baltimore, Maryland); Hermenegild Arevalo (Baltimore, Maryland); Natalia Trayanova (Baltimore, Maryland); Katherine Wu (Bel Air, Maryland)
ABSTRACT	A method of determining a likelihood of an occurrence of a cardiac arrhythmia in a patient includes receiving three-dimensional imaging data of said patient's heart, constructing a whole-heart model for simulating at least one of electrophysiological activity or electromechanical activity of the patient's heart using the three-dimensional imaging data, simulating a response of the patient's heart to each of a plurality of stimulations to a corresponding plurality of different locations within the patient's heart using the whole-heart model, classifying each simulation outcome for each stimulation as one of a normal heart rhythm or a cardiac arrhythmia, calculating a likelihood index based on results of the classifying, and determining the likelihood of the occurrence of the cardiac arrhythmia in the patient based on the likelihood index. Software and data processing systems that implement the above methods are also provided.
FILED	Tuesday, October 30, 2012
APPL NO	13/694120
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/7275 (20130101) Original (OR) Class A61B 6/503 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 2207/10088 (20130101) G06T 2207/20128 (20130101) G06T 2207/30048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 20/40 (20180101) G16H 30/40 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101)
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10828143 — Tissue-engineered bowel constructs

US 10828143	Bitar
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	Khalil Bitar (Winston-Salem, North Carolina)
ABSTRACT	Methods are disclosed for forming tissue engineered, tubular bowel constructs from intestinal circular smooth muscle cells and enteric neural progenitor cells. The intestinal smooth muscle cells and neural progenitor cells can be seeded on a mold with a surface texture that induces longitudinal alignment of the intestinal smooth muscle cells and co-cultured until an innervated aligned smooth muscle sheet is obtained. The innervated smooth muscle sheet can then be wrapped around a tubular scaffold to form an intestinal tissue construct.
FILED	Thursday, November 09, 2017
APPL NO	15/808338
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0004 (20130101) A61F 2/04 (20130101) Original (OR) Class A61F 2/08 (20130101) A61F 2002/045 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/383 (20130101) A61L 27/3826 (20130101) A61L 27/3834 (20130101) A61L 27/3873 (20130101) A61L 27/3886 (20130101) A61L 2430/30 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0697 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2502/088 (20130101) C12N 2502/1347 (20130101)
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10828255 — Lipid bilayer coated mesoporous silica nanoparticles with a high loading capacity for one or more anticancer agents

US 10828255	Nel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Andre E. Nel (Los Angeles, California); Jeffrey I. Zink (Los Angeles, California); Huan Meng (Los Angeles, California)
ABSTRACT	A submicron structure comprising a silica body defining a plurality of pores that are suitable to receive molecules therein, and having a surface, and a phospholipid bilayer coating the surface, wherein said submicron structure has a maximum dimension of less than one micron, and wherein the phospholipid bilayer stably seals the plurality of pores; and wherein the submicron structure is a member of a monodisperse population of submicron structures.
FILED	Wednesday, March 05, 2014
APPL NO	14/772740
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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10828323 — Topical compositions and methods of using the same

US 10828323	Doxey et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Novan, Inc. (Morrisville, North Carolina)
ASSIGNEE(S)	Novan, Inc. (Morrisville, North Carolina)
INVENTOR(S)	Ryan Doxey (Raleigh, North Carolina); Jian Bao (Cary, North Carolina)
ABSTRACT	The present invention generally relates to topical compositions and methods of using the same. The topical compositions may comprise a hydrophilic composition and a hydrophobic composition in admixture. The hydrophobic composition may include a nitric oxide-releasing compound such as, for example, a diazeniumdiolate functionalized co-condensed silica particle. In some embodiments, the topical composition may be self-emulsifying. Further described herein are kits comprising a hydrophilic composition and a hydrophobic composition.
FILED	Friday, January 18, 2019
APPL NO	16/251972
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/25 (20130101) A61K 8/042 (20130101) A61K 8/345 (20130101) A61K 8/898 (20130101) A61K 9/06 (20130101) A61K 9/10 (20130101) A61K 9/0014 (20130101) A61K 9/107 (20130101) A61K 33/00 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) A61K 47/44 (20130101) A61K 47/52 (20170801) A61K 47/59 (20170801) A61K 2800/22 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/005 (20130101) A61Q 19/00 (20130101)
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10828331 — Cellular compositions used to restore stem cell or progenitor cell function and methods related thereto

US 10828331	Yoon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Emory University (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Young-Sup Yoon (Atlanta, Georgia); Ji Woong Han (Decatur, Georgia)
ABSTRACT	This disclosure relates to compounds, compositions and methods of epigenetically transforming cells. In certain embodiments, the disclosure relates to methods of generating epigenetically altered cells comprising mixing isolated cells with compositions disclosed herein under conditions such that epigenetically altered cells are formed. In certain embodiments, methods of treating or preventing vascular or diabetic diseases or conditions are contemplated. In certain embodiments, epigenetically reprogramming adult bone marrow-derived stem or progenitor cells including mesenchymal stem cells (MSCs) or endothelial progenitor cells (EPCs) for autologous treatments are contemplated.
FILED	Thursday, February 23, 2017
APPL NO	15/440555
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 35/44 (20130101) Heterocyclic Compounds C07D 239/95 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2501/40 (20130101) C12N 2501/065 (20130101)
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10828333 — Point-of-care and/or portable platform for gene therapy

US 10828333	Adair et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	Jennifer E. Adair (Seattle, Washington); Hans-Peter Kiem (Seattle, Washington)
ABSTRACT	A platform for ex vivo isolation, production, and formulation of genetically-modified cells is described. The platform utilizes a software-enabled point-of-care and/or portable device making gene therapy more widely available.
FILED	Friday, May 24, 2019
APPL NO	16/422876
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) C12M 47/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8673 (20130101) C12N 2740/16043 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101)
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10828350 — Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment

US 10828350	Bermudes et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	David Gordon Bermudes (Woodland Hills, California)
ASSIGNEE(S)
INVENTOR(S)	David Gordon Bermudes (Woodland Hills, California); David Quintero (Northridge, California)
ABSTRACT	The present invention provides purified protease inhibitors derived from microorganisms alone or in combination with bacteriocins and/or antibodies. The protease inhibitors may also be expressed by microbiome or probiotic microorganisms alone or in combination with bacteriocins and/or antibodies. The invention also provides methods and compositions for improving the expression of endogenous or heterologous protease inhibitors alone or in combination with bacteriocins and/or antibodies. The invention is useful for treating a variety of inflammatory disorders including acne, psoriasis, eczema, atopic dermatitis and inflammatory bowel disease.
FILED	Thursday, August 17, 2017
APPL NO	15/679896
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/55 (20130101) Original (OR) Class Peptides C07K 14/81 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/81 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101)
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10828352 — Compositions and methods for boosting the efficacy of adoptive cellular immunotherapy

US 10828352	Berger et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	Susanna Carolina Berger (Seattle, Washington); Stanley R. Riddell (Sammamish, Washington)
ABSTRACT	The present disclosure provides compositions and methods for boosting, augmenting or enhancing the efficacy of the adoptive cellular immunotherapy by using modified T cells expressing an antigen binding protein in conjunction with modified cells (such as hematopoietic progenitor cells, modified human immune system cells or a combination thereof) expressing the antigen specifically bound by the antigen binding protein of the modified T cells.
FILED	Tuesday, October 27, 2015
APPL NO	15/521794
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 39/00111 (20180801) A61K 39/00117 (20180801) A61K 39/395 (20130101) A61K 39/001103 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001112 (20180801) A61K 39/001113 (20180801) A61K 39/001117 (20180801) A61K 39/001122 (20180801) A61K 39/001124 (20180801) A61K 39/001129 (20180801) A61K 39/001153 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001168 (20180801) A61K 39/001171 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001195 (20180801) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) A61K 2039/55522 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70578 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101)
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10828353 — Compositions and methods for T cell delivery of therapeutic molecules

US 10828353	Zhao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Yangbing Zhao (Lumberton, New Jersey); Carl H. June (Merion Station, Pennsylvania); Xiaojun Liu (Swarthmore, Pennsylvania)
ABSTRACT	The present invention includes compositions and methods for modifying a T cell with a nucleic acid encoding a switch molecule comprising an extracellular domain comprising a membrane receptor or fragment thereof and an intracellular domain comprising a signaling receptor or fragment thereof. In one aspect, a method comprises introducing a nucleic acid encoding a switch molecule and a nucleic acid encoding a soluble fusion protein and/or a nucleic acid encoding a bispecific antibody into a population of cells comprising T cells, wherein the T cells transiently expresses the switch molecule and soluble fusion protein or bispecific antibody. In other aspect, compositions of T cells and methods of treating a disease or condition, such as cancer or an autoimmune disease, are also included.
FILED	Friday, October 30, 2015
APPL NO	15/544816
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00115 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001122 (20180801) A61K 39/001124 (20180801) A61K 39/001151 (20180801) A61K 39/001153 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001164 (20180801) A61K 39/001171 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 39/001195 (20180801) A61K 39/39558 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/71 (20130101) C07K 14/7155 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 16/2863 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/10 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/00 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101)
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10828364 — Method for reducing a myeloid derived suppressor cell population with cationic lipid vaccine compositions

US 10828364	Johnson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	PDS BIOTECHNOLOGY CORPORATION (North Brunswick, New Jersey); THE GOVERNMENT OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES (Rockville, Maryland)
ASSIGNEE(S)	PDS Biotechnology Corporation (North Brunswick, New Jersey); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC. OF THE DEPT. OF HEALTH AND HUMAN SERVICES (Rockville, Maryland)
INVENTOR(S)	Kenya Johnson (Mason, Ohio); Eric Jacobson (Cincinnati, Ohio); Frank Bedu-Addo (Bethel, Connecticut); Mikayel Mkrtichyan (Rockville, Maryland); Samir N. Khleif (Silver Spring, Maryland)
ABSTRACT	The present disclosure provides vaccine compositions comprising at least one adjuvant and at least one therapeutic factor. The disclosure also provides methods of reducing an immune suppressor cell population in a mammal, methods of argumenting an immune response in a mammal, and methods of treating a diseases in a mammal utilizing the vaccine compositions.
FILED	Thursday, March 28, 2019
APPL NO	16/367546
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0005 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/585 (20130101) A61K 2039/55511 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/20034 (20130101)
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10828367 — Photoswitchable HDAC inhibitors

US 10828367	Mazitschek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Ralph Mazitschek (Belmont, Massachusetts); Balaram Ghosh (Boston, Massachusetts); James Adam Hendricks (Watertown, Massachusetts); Surya Reis (Boston, Massachusetts); Stephen John Haggarty (Dorchester, Massachusetts)
ABSTRACT	This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
FILED	Tuesday, May 01, 2018
APPL NO	15/968634
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 245/08 (20130101) C07C 259/06 (20130101) C07C 259/10 (20130101) Heterocyclic Compounds C07D 333/20 (20130101) C07D 409/14 (20130101) C07D 491/16 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101)
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10828370 — Selectin and ICAM/VCAM peptide ligand conjugates

US 10828370	Panitch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Alyssa Panitch (Davis, California); Rebecca Scott (West Lafayette, Indiana); Kinam Park (West Lafayette, Indiana); James Wodicka (West Lafayette, Indiana)
ABSTRACT	The invention relates to peptide conjugates that can bind to endothelial cells, and that are useful for reducing the incidence and severity of endothelial dysfunction in mammals.
FILED	Tuesday, May 12, 2015
APPL NO	15/310416
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/42 (20130101) Original (OR) Class A61K 47/61 (20170801) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 9/14 (20180101) A61P 29/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Peptides C07K 14/4725 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0021 (20130101) C08B 37/0069 (20130101) C08B 37/0072 (20130101)
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10828372 — Compositions and methods for the inhibition of fibrosis

US 10828372	Tomasini-Johansson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Bianca R. Tomasini-Johansson (Madison, Wisconsin); Glen S. Kwon (Madison, Wisconsin); Pawel Waldemar Zbyszynski (Chicago, Illinois); Nathan Sandbo (Middleton, Wisconsin); Ksenija Bernau (Madison, Wisconsin)
ABSTRACT	Described herein is a mono-end PEGyated functional upstream domain (FUD), pharmaceutical compositions, and its use to inhibit fibrosis such as organ fibrosis, idiopathic pulmonary fibrosis and fibrosis associated with cancer. Also included are methods of probing for injured or repairing tissue in an individual in need thereof using the mono-end PEGyated-FUD.
FILED	Monday, November 12, 2018
APPL NO	16/186864
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0029 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) Original (OR) Class A61K 49/0056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) A61P 43/00 (20180101)
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10828374 — Targeting macula densa cells as a new therapeutic approach for kidney disease

US 10828374	Peti-Peterdi
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	MACULA DENSA CELL LLC (Palos Verdes Estates, California)
ASSIGNEE(S)	MACULA DENSA CELL LLC (Palos Verdes Estates, California)
INVENTOR(S)	Janos Peti-Peterdi (Los Angeles, California)
ABSTRACT	There is no specific cure for chronic kidney disease (CKD), which affects one in every ten adults. The unmet medical need has created significant interest in regenerative therapeutic approaches. Described herein is a radically new and innovative therapeutic approach identified by characterizing a novel mechanism of renal tissue repair and its role in glomerular injury. By targeting this mechanism in CKD, significant therapeutic benefit supported by rapid cellular remodeling of kidney tissues, coincident with structural and functional nephron regeneration. Methods and compositions for achieving the described therapeutic approach are fundamentally different from existing strategies.
FILED	Tuesday, November 07, 2017
APPL NO	15/806221
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) Original (OR) Class A61K 47/6455 (20170801) A61K 49/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/47 (20130101) C07K 14/475 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101)
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10828379 — In vivo differentiation of relative oxygen levels and tumor necrosis using divalent europium

US 10828379	Allen
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S)	WAYNE STATE UNIVERSITY (Detroit, Michigan)
INVENTOR(S)	Matthew J. Allen (Plymouth, Michigan)
ABSTRACT	A method of magnetic resonance imaging a target tissue in a subject includes a step of administering a first Eu²⁺-containing complex to the subject. The first Eu²⁺-containing complex has a reduction potential that is more negative than a reduction potential for a selected compound present in the target tissue. A first set of images of the target tissue in the subject is then taken by T₁-weighted magnetic resonance imaging.
FILED	Friday, March 11, 2016
APPL NO	15/067901
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/106 (20130101) Original (OR) Class
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10828381 — RNA nanoparticles and method of use thereof

US 10828381	Guo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
ASSIGNEE(S)	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S)	Peixuan Guo (Columbus, Ohio); Hui Li (Columbus, Ohio); Wei Luo (Lexington, Kentucky)
ABSTRACT	The presently-disclosed subject matter relates to an artificial RNA nanostructure and method of use thereof. In particular, the presently-disclosed subject matter relates to RNA nanoparticles and RNA dendrimers, and methods of disease diagnosis and treatments using the RNA nanostructure and RNA dendrimers.
FILED	Sunday, April 17, 2016
APPL NO	15/566972
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/12 (20130101) A61K 51/0491 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/52 (20130101) C12N 2310/113 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/322 (20130101) C12N 2310/3517 (20130101) C12N 2310/3519 (20130101) C12N 2310/3533 (20130101)
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10828393 — Si—O—N—P related fabrication methods, surface treatments and uses thereof

US 10828393	Varanasi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	The Texas A and M University System (College Station, Texas); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas); Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Venu Varanasi (Lewisville, Texas); Pranesh Aswath (Grapevine, Texas); Philip Kramer (Dallas, Texas); Megen Velten (Beeville, Texas); Azhar Ilyas (Arlington, Texas)
ABSTRACT	Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of Si—O—N—P. These coatings and/or layers may be continuous, on the surface or discontinuous (e.g., patterned, grooved), and may be provided on silica surfaces, metal (e.g., titanium), ceramic, and combination/hybrid materials. Methods of producing an implantable device, such as a load-bearing or non-load-bearing device, such as a bone or other structural implant device (load-bearing), are also presented. Craniofacial, osteogenic and disordered bone regeneration (osteoporosis) uses and applications of devices that include at least one surface that is treated to include a nanoscale or microscale layer or coating of Si—O—N—P are also provided. Methods of using the treated and/or coated devices to enhance enhanced vascularization and healing at a treated surface of a device in vivo, is also presented.
FILED	Thursday, March 09, 2017
APPL NO	15/455120
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0006 (20130101) A61C 8/0015 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/3094 (20130101) A61F 2/30771 (20130101) A61F 2002/3084 (20130101) A61F 2002/3093 (20130101) A61F 2310/0061 (20130101) A61F 2310/00796 (20130101) A61F 2310/00874 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/10 (20130101) A61L 27/32 (20130101) Original (OR) Class A61L 27/38 (20130101) A61L 27/54 (20130101) A61L 2300/112 (20130101) A61L 2300/412 (20130101) A61L 2300/606 (20130101) A61L 2400/12 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) A61L 2420/06 (20130101) A61L 2430/02 (20130101) A61L 2430/12 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/597 (20130101) C04B 35/5154 (20130101) C04B 2235/42 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 7/60 (20180101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/22 (20130101) C23C 16/30 (20130101) C23C 16/50 (20130101)
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10828414 — Magnetic filtration devices and methods related thereto

US 10828414	Mabray et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Marc C. Mabray (San Francisco, California); Steven W. Hetts (Hillsborough, California); Prasheel V. Lillaney (San Francisco, California); Aaron D. Losey (San Francisco, California); Caroline D. Jordan (San Francisco, California); Sravani Kondapavulur (San Jose, California); Andre M. Cote (Daly City, California)
ABSTRACT	In vivo and ex vivo positionable magnetic filtration devices are provided that magnetically filter one or more therapeutic agents conjugated to a magnetic particle in blood flowing in a blood vessel.
FILED	Wednesday, February 17, 2016
APPL NO	15/551245
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/01 (20130101) A61F 2/011 (20200501) A61F 2210/009 (20130101) A61F 2250/0014 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 41/00 (20130101) A61K 47/6929 (20170801) A61K 51/1244 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/04 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3615 (20140204) A61M 1/3618 (20140204) Original (OR) Class A61M 2202/0468 (20130101) A61M 2205/04 (20130101)
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10828436 — Administering the noble gas argon during cardiopulmonary resuscitation

US 10828436	Riess et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee); Medical College of Wisconsin (Milwaukee, Wisconsin)
INVENTOR(S)	Matthias L. Riess (Nashville, Tennessee); Demetris Yannopoulos (Minneapolis, Minnesota); Tom P. Aufderheide (Milwaukee, Wisconsin)
ABSTRACT	Method of treating an individual following a period of ischemia are provided. The methods include administering inhaled agents postconditioning to the individual and optionally simultaneously performing cardiopulmonary resuscitation. The inhaled agents include at least one noble gas.
FILED	Wednesday, April 05, 2017
APPL NO	15/480280
ART UNIT	3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 31/00 (20130101) A61H 2201/5071 (20130101) A61H 2230/42 (20130101) A61H 2230/205 (20130101) A61H 2230/207 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 41/0004 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/00 (20130101) Original (OR) Class A61M 16/0003 (20140204) A61M 16/12 (20130101) A61M 16/0078 (20130101) A61M 2202/02 (20130101) A61M 2202/02 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/025 (20130101) A61M 2202/025 (20130101) A61M 2202/0208 (20130101) A61M 2202/0208 (20130101) A61M 2202/0258 (20130101) A61M 2202/0258 (20130101) A61M 2205/05 (20130101) A61M 2230/40 (20130101)
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10828513 — Ionizing-radiation beam monitoring system

US 10828513	Friedman
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
INVENTOR(S)	Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT	A transmissive ionizing-radiation beam monitoring system includes an enclosure structure with at least one ultra-thin window to an incident ionizing-radiation beam, where the ultra-thin window is highly transmissive to ionizing-radiation. Embodiments include at least one thin or ultra-thin scintillator within the enclosure structure that is substantially directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam, and at least one ultraviolet (UV) illumination source within the enclosure structure facing the scintillator. Embodiments include at least one machine vision camera within the enclosure structure located out of an incident ionizing-radiation beam path and including a camera body and lens having a projection of its optical axis oriented at an angle of incidence of 45±35 degrees to a surface of the scintillator.
FILED	Friday, March 06, 2020
APPL NO	16/811471
ART UNIT	2884 — Optics
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101)
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10828636 — Automated remotely instructed driving of an assay

US 10828636	Linbeck, III et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Fannin Innovation Studio, Inc. (Houston, Texas)
ASSIGNEE(S)	FANNIN PARTNERS LLC (Houston, Texas)
INVENTOR(S)	Leo Linbeck, III (Houston, Texas); Michael John Heffernan (Katy, Texas); Dev Chatterjee (Houston, Texas); Atul Varadhachary (Bellaire, Texas)
ABSTRACT	The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.
FILED	Wednesday, October 25, 2017
APPL NO	15/793384
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0237 (20130101) B01L 3/0289 (20130101) B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 2200/027 (20130101) B01L 2200/0668 (20130101) B01L 2300/021 (20130101) B01L 2300/023 (20130101) B01L 2300/042 (20130101) B01L 2300/087 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/00 (20130101) G01N 35/00871 (20130101) G01N 35/1065 (20130101) G01N 2035/00851 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 99/00 (20130101)
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10829393 — Water detoxification by a substrate-bound catecholamine adsorbent

US 10829393	Messersmith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Phillip B. Messersmith (Clarendon Hills, Illinois); Haeshin Lee (Daejeon, South Korea)
ABSTRACT	A bio-inspired method for detoxifying contaminated water is disclosed. In the method, polydopamine, a mussel-inspired adhesive catecholamine was used as an adsorbent to effectively remove from contaminated water three major classes of toxic agents: heavy metal ions (e.g., Cr, Hg, Pb, Cu, and Cd), toxic organic species (e.g., 4-aminopyridine), and radioisotopes (e.g., Lutetium-177). Furthermore, the polydopamine adsorbent was regenerated by treatment with acid or hydrogen peroxide.
FILED	Monday, October 08, 2018
APPL NO	16/154624
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/262 (20130101) B01J 20/345 (20130101) B01J 20/3204 (20130101) B01J 20/3206 (20130101) B01J 20/3208 (20130101) B01J 20/3272 (20130101) B01J 20/3293 (20130101) B01J 20/3475 (20130101) B01J 20/28016 (20130101) B01J 20/28019 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 1/286 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 2101/006 (20130101) C02F 2101/20 (20130101) C02F 2101/22 (20130101) C02F 2101/30 (20130101) C02F 2101/38 (20130101) C02F 2303/16 (20130101)
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10829440 — Antibacterial compounds and methods of making and using same

US 10829440	Basu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Brown University (Providence, Rhode Island); Bryant University (Smithfield, Rhode Island)
ASSIGNEE(S)	Brown University (Providence, Rhode Island); Bryant University (Smithfield, Rhode Island)
INVENTOR(S)	Amit Basu (Barrington, Rhode Island); Christopher W. Reid (Cumberland, Rhode Island); Mary Margaret O'Connor (North Jupiter, Florida); Ethan Lindsay Magno (Lexington, Massachusetts); Mitchell Evan Jamieson (Macomb, Michigan); Ryan Daniel Miller (Smithfield, Rhode Island)
ABSTRACT	The invention provides novel antibacterial diamide compounds, pharmaceutical compositions comprising the compounds and methods for treating or preventing an infection in a subject using the compounds.
FILED	Friday, June 10, 2016
APPL NO	15/570923
ART UNIT	1699 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 237/14 (20130101) Original (OR) Class C07C 2601/08 (20170501) C07C 2601/14 (20170501) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/481 (20180101) Y02A 50/483 (20180101)
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10829453 — Antagonists of the kappa opioid receptor

US 10829453	Aube et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	Jeffrey Aube (Lawrence, Kansas); Kevin Frankowski (Lawrence, Kansas); Thomas Prisinzano (Lawrence, Kansas); Laura Bohn (Jupiter, Florida)
ABSTRACT	The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
FILED	Friday, November 02, 2018
APPL NO	16/179637
ART UNIT	1699 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/44 (20130101) C07D 217/08 (20130101) Original (OR) Class C07D 223/16 (20130101)
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10829471 — Piperidinyl nociceptin receptor compounds

US 10829471	Zaveri et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute on Drug Abuse (NIDA) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Astraea Therapeutics, Inc. (Mountain View, California)
ASSIGNEE(S)	Astraea Therapeutics, LLC (, None)
INVENTOR(S)	Nurulain Zaveri (Saratoga, California); Dennis Yasuda (Campbell, California)
ABSTRACT	The present invention provides novel piperidinyl-containing nociceptin receptor ligand compounds and pharmaceutical compositions useful in the treatment of neurological diseases and conditions where such ligands mediate the negative effects of the condition. Such neurological diseases and conditions include acute and chronic pain, substance abuse/dependence, alcohol addiction, anxiety, depression, sleep disorders, gastrointestinal disorders, renal disorders, cardiovascular disorders and Parkinson's disease.
FILED	Thursday, June 06, 2019
APPL NO	16/433506
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101)
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10829477 — Activity-based probe compounds, compositions, and methods of use

US 10829477	Bogyo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Matthew S. Bogyo (Redwood City, California); Martijn Verdoes (Nijmegen, Netherlands)
ABSTRACT	Activity-based probe compounds for use in labeling a cysteine protease are provided. The compounds are targeted to the protease through a specific targeting element. The compounds additionally include a detectable element, such as a fluorescent label, a radiolabel, or a chelator. In some cases, the compounds additionally include a quenching element that is released upon reaction with the protease. Also provided are compositions comprising the compounds and methods for using the compounds, for example in labeling a protease in an animal and in visualizing a tumor in an animal.
FILED	Tuesday, October 02, 2018
APPL NO	16/150167
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0041 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class
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10829518 — Peptide compositions and methods of use

US 10829518	Besirli et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	ONL Therapeutics, Inc. (Ann Arbor, Michigan); The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	ONL THERAPEUTICS. INC. (Ann Arbor, Michigan); THE REGENT OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Cagri G. Besirli (Ann Arbor, Michigan); Alexander J. Bridges (Saline, Michigan); John K. Freshley (Ann Arbor, Michigan); William A. Hunke (Middletown, Delaware); Linda L. Johnson (Ann Arbor, Michigan); Francis X. Smith (Salem, New Hampshire); Ethan Sylvain (Manchester, New Hampshire); David N. Zacks (Ann Arbor, Michigan)
ABSTRACT	Provided herein are compositions including peptides, pharmaceutical preparations thereof, and methods of preventing photoreceptor death therewith and protecting of retinal cells, including, but not limited to, photoreceptors and retinal pigment epithelium, from Fas- or TRAIL-mediated apoptosis.
FILED	Monday, November 04, 2019
APPL NO	16/673513
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/71 (20130101) Technologies for Adaptation to Climate Change Y02A 50/401 (20180101) Y02A 50/423 (20180101)
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10829525 — Mutant NGAL proteins and uses thereof

US 10829525	Barasch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Jonathan Barasch (New York, New York); Andong Qiu (Bronx, New York)
ABSTRACT	In one aspect the present invention is directed to mutant NGAL proteins that have the ability to bind to siderophores, such as enterochelin, and to chelate and transport iron, and that are excreted in the urine. Such NGAL mutants, and complexes thereof with siderophores, can be used to clear excess iron from the body, for example in the treatment of iron overload. The NGAL mutants of the invention also have antibacterial activity and can be used in the treatment of bacterial infections, such as those of the urinary tract.
FILED	Wednesday, March 08, 2017
APPL NO	15/453109
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class
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10829526 — Method of treating vitiligo using mutant HSP70i

US 10829526	Le Poole et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Loyola University of Chicago (Maywood, Illinois)
ASSIGNEE(S)	LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	I. Caroline Le Poole (Downers Grove, Illinois); Jose Alejandro Guevara (Chicago, Illinois); Andrew Zloza (Chicago, Illinois)
ABSTRACT	Methods of treating autoimmune diseases, such as vitiligo, by using compositions comprising DNA encoding a variant inducible heat shock protein 70 (HSP70i) having a mutation in the dendritic cell binding region thereof (HSP70i435-447) or an isolated variant gene product in the form of HSP70i with a modification in the dendritic cell activating region thereof (HSP70i435-447).
FILED	Tuesday, October 24, 2017
APPL NO	15/791609
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0325 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 48/005 (20130101) Peptides C07K 14/47 (20130101) C07K 14/4705 (20130101) Original (OR) Class
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10829536 — Methods of promoting CNS neuronal repair by inhibiting LRP-1

US 10829536	Gonias et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Steven L. Gonias (San Diego, California); Travis Stiles (San Diego, California); Alban Gaultier (Charlottesville, Virginia); Wendy M. Campana (La Jolla, California); Katerina Akassoglou (San Francisco, California)
ABSTRACT	This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
FILED	Wednesday, June 22, 2016
APPL NO	15/189965
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101)
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10829543 — Compositions and methods for inhibiting pathogen infection

US 10829543	Lai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Samuel Lai (Carrboro, North Carolina); Ying-Ying Wang (San Francisco, California); Arthi Kannan (Union City, California); Kenetta Nunn (Moscow, Idaho); Durai Babu Subramani (Chapel Hill, North Carolina); Richard Cone (Baltimore, Maryland); Bing Yang (Chapel Hill, North Carolina); Justin Mccallen (Greenville, North Carolina)
ABSTRACT	The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating virus infection in the respiratory tract and virus transmission through the respiratory tract. In particular, the presently-disclosed subject matter relates to inhibiting and treating virus infection in a subject using compositions and antibodies that trap viruses in mucus of the respiratory tract, thereby inhibiting transport of virus across or through mucus secretions.
FILED	Friday, September 21, 2018
APPL NO	16/138643
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/544 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/12 (20180101) A61P 31/14 (20180101) A61P 31/22 (20180101) Peptides C07K 16/10 (20130101) C07K 16/087 (20130101) Original (OR) Class C07K 16/1027 (20130101) C07K 16/1214 (20130101) C07K 2317/13 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/41 (20130101) C07K 2317/54 (20130101) C07K 2317/76 (20130101)
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10829548 — Targeting CLPTM1L for treatment and prevention of cancer

US 10829548	James
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin)
ASSIGNEE(S)	The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S)	Michael A. James (Big Bend, Wisconsin)
ABSTRACT	Provided herein are therapeutic agents having specificity for human CLPTM1L polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L protein dysfunction (e.g., pathogenic production, modification, or function).
FILED	Thursday, February 28, 2019
APPL NO	16/289023
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3069 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101)
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10829672 — Water compatible nanogel compositions

US 10829672	Stansbury
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S)	Jeffrey W. Stansbury (Centennial, Colorado)
ABSTRACT	The present invention relates to preparation and use of water dispersible nanogels and solvent dispersible reactive nanogels as additives to enhance polymer properties or as precursors to polymeric networks.
FILED	Monday, December 18, 2017
APPL NO	15/845905
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/18 (20130101) C08F 220/20 (20130101) C08F 220/306 (20200201) C08F 222/1006 (20130101) C08F 265/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) C08J 2205/02 (20130101) C08J 2333/14 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 133/14 (20130101) Original (OR) Class
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10829752 — Bacterial toxins and uses thereof as Ras specific proteases for treating cell proliferation diseases and disorders

US 10829752	Satchell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Karla J. F. Satchell (Evanston, Illinois); Irena Antic (Chicago, Illinois); Marco Biancucci (Chicago, Illinois)
ABSTRACT	Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer.
FILED	Thursday, April 19, 2018
APPL NO	15/957396
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/22 (20130101)
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10829757 — MUB motif is an inhibitor of E2-ubiquitin thioester formation

US 10829757	Downes et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Saint Louis University (St. Louis, Missouri)
ASSIGNEE(S)	Saint Louis University (St. Louis, Missouri)
INVENTOR(S)	Brian Downes (Edwardsville, Illinois); Sergey V. Korolev (Manchester, Missouri); Xiaolong Lu (St. Louis, Missouri)
ABSTRACT	The present disclosure provides for peptides derived from membrane-anchored ubiquitin-fold proteins (MUB), particularly those containing a Lap-Bar-Lopp motif, for use in inhibiting ubiquitinylation.
FILED	Friday, March 24, 2017
APPL NO	16/087737
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Original (OR) Class
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10829765 — STAT3 inhibitors and uses thereof

US 10829765	Kortylewski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	Marcin Tomasz Kortylewski (Monrovia, California); Piotr Marek Swiderski (San Dimas, California)
ABSTRACT	Described herein, inter alia, are STAT-binding nucleic acids-including compositions and methods of using the same.
FILED	Friday, May 18, 2018
APPL NO	15/984086
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 47/64 (20170801) A61K 47/549 (20170801) A61K 2039/55561 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/117 (20130101) Original (OR) Class C12N 2310/13 (20130101) C12N 2310/17 (20130101) C12N 2310/315 (20130101) C12N 2310/351 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101)
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10829766 — Chimeric polypeptides having targeted binding specificity

US 10829766	Barbas, III et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of General Medical Sciences (NIGMS) NIH Office of the Director (NIHOD)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Carlos F. Barbas, III (La Jolla, California); Andrew Mercer (Poolesville, Maryland); Brian M. Lamb (San Diego, California); Thomas Gaj (Solana Beach, California)
ABSTRACT	Disclosed herein are chimeric polypeptides, including compositions thereof, expression vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors, and methods of the present invention are also useful in gene therapy techniques.
FILED	Tuesday, January 23, 2018
APPL NO	15/878043
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 15/62 (20130101) Original (OR) Class
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10829767 — Chimeric antigen receptors targeting B-cell maturation antigen

US 10829767	Kochenderfer
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	James N. Kochenderfer (Bethesda, Maryland)
ABSTRACT	The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
FILED	Thursday, November 14, 2019
APPL NO	16/683494
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class
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10829768 — Chimeric antigen receptors targeting B-cell maturation antigen

US 10829768	Kochenderfer
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	James N. Kochenderfer (Bethesda, Maryland)
ABSTRACT	The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
FILED	Friday, November 15, 2019
APPL NO	16/684962
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class
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10829769 — Chimeric antigen receptors targeting b-cell maturation antigen

US 10829769	Kochenderfer
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	James N. Kochenderfer (Bethesda, Maryland)
ABSTRACT	The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
FILED	Friday, November 15, 2019
APPL NO	16/684994
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class
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10829800 — Systems and methods for enhanced SCODA

US 10829800	Marziali et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The University of British Columbia (Vancouver, Canada)
ASSIGNEE(S)	The University of British Columbia (Vancouver, Canada)
INVENTOR(S)	Andrea Marziali (North Vancouver, Canada); Joel Pel (Vancouver, Canada); Jason Donald Thompson (Vancouver, Canada); Gosuke Shibahara (Vancouver, Canada)
ABSTRACT	Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.
FILED	Wednesday, July 17, 2019
APPL NO	16/514690
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 7/023 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) C12N 15/1003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) C12Q 2527/146 (20130101) C12Q 2537/164 (20130101) C12Q 2565/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/574 (20130101) G01N 33/689 (20130101) G01N 33/5308 (20130101) G01N 2800/385 (20130101)
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10829804 — Method for identification and enumeration of nucleic acid sequences, expression, splice variant, translocation, copy, or DNA methylation changes using combined nuclease, ligase, polymerase, terminal transferase, and sequencing reactions

US 10829804	Barany et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Francis Barany (New York, New York); John William Efcavitch (San Carlos, California); Steven A. Soper (Baton Rouge, Louisiana); Sunggook Park (Baton Rouge, Louisiana)
ABSTRACT	The present invention is directed methods for identifying, in a sample, one or more target nucleotide sequences differing from other nucleotide sequences in the sample by one or more nucleotides, one or more copy numbers, one or more transcript sequences, and/or one or more methylated residues, using ligation detection reactions, polymerase mediated extension reactions, and/or cleavage reactions. The present invention is also directed to methods for identifying, in a sample, one or more nucleotides in a target nucleotide sequence.
FILED	Wednesday, March 23, 2016
APPL NO	15/560805
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2521/301 (20130101) C12Q 2521/331 (20130101) C12Q 2531/125 (20130101) C12Q 2535/125 (20130101) C12Q 2561/109 (20130101) C12Q 2561/125 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101)
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10829814 — Methods and compositions for single cell genomics

US 10829814	Fan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) U.S. Public Health Service (USPHS)
APPLICANT(S)	Illumina, Inc. (San Diego, California); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	Illumina, Inc. (San Diego, California); The Regents of the University of Caliofrnia (Oakland, California)
INVENTOR(S)	Jian-Bing Fan (San Diego, California); Kun Zhang (San Diego, California)
ABSTRACT	Presented are methods and compositions for obtaining sequence information from one or more individual cells. The methods are useful for obtaining sequence information for a single nucleotide sequence, and for multiplex generation of sequence information from one or more individual cells.
FILED	Wednesday, June 17, 2015
APPL NO	14/742027
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2561/125 (20130101) C12Q 2561/125 (20130101)
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10829823 — Compositions and methods for the rapid differential detection of Zika virus

US 10829823	Lipkin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Walter Ian Lipkin (New York, New York); Nischay Mishra (New York, New York); Thomas Briese (White Plains, New York); Rafal Tokarz (Queens Village, New York)
ABSTRACT	This invention relates to compositions and methods for the differential detection of multiple viruses using a one-step assay. The viruses to be detected include Zika, West Nile, dengue (genotype 1-4) and chikungunya viruses. In particular, the invention relates to a method of and assay for differential detection of the viruses using specific primers and probes designed to detect and differentiate between the viruses.
FILED	Friday, March 17, 2017
APPL NO	16/085825
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/701 (20130101) C12Q 1/6806 (20130101) C12Q 1/6888 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/166 (20130101)
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10830639 — Devices, methods, and systems relating to super resolution imaging

US 10830639	Urban et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Eye Institute (NEI) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ben Urban (Evanston, Illinois); Hao F. Zhang (Deerfield, Illinois); Cheng Sun (Wilmette, Illinois); Biqin Dong (Evanston, Illinois)
ABSTRACT	Certain examples disclose systems and methods for imaging a target. An example method includes: a) activating a subset of light-emitting molecules in a wide field area of a target using an excitation light; b) capturing one or more images of the light emitted from the subset of the molecules illuminated with the excitation light; c) localizing one or more activated light emitting molecules using one or more single molecule microscopic methods to obtain localization information; d) simultaneously capturing spectral information for the same localized activated light emitting molecules using one or more spectroscopic methods; e) resolving one or more non-diffraction limited images of the area of the target using a combination of the localization and spectral information for the localized activated light emitting molecules; and f) displaying the one or more non-diffraction limited images.
FILED	Friday, September 25, 2015
APPL NO	15/514084
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/84 (20130101) G01N 21/6458 (20130101) G01N 33/483 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0064 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101)
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10830678 — Photo-controlled removal of targets in vitro and in vivo

US 10830678	Kobayashi et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (Bethesda, Maryland)
INVENTOR(S)	Hisataka Kobayashi (Laurel, Maryland); Peter Choyke (Rockville, Maryland); Martin John Schnermann (Rockville, Maryland)
ABSTRACT	This disclosure provides IR700-molecule conjugates and methods of their use to remove (e.g., separate or isolate) a target from a sample in vivo or from a subject in vitro. It is shown herein that exposure of IR700 to near infrared (NIR) light removes a portion of IR700, changing it from a hydrophilic molecule, to one that is hydrophobic, resulting in aggregation of IR700 and anything bound to it. For example, the disclosed IR700-molecule conjugates and methods provide photo-controlled ways to control the pharmacokinetics of a drug in vivo, and can be used to remove undesired agents from environmental or food samples or to isolate target molecules in a laboratory.
FILED	Friday, August 07, 2015
APPL NO	15/318104
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 41/0071 (20130101) A61K 47/6891 (20170801) A61K 49/0036 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0651 (20130101) A61N 2005/0663 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) Original (OR) Class G01N 1/405 (20130101) G01N 33/5002 (20130101)
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10830757 — Universal molecular processor for precision medicine

US 10830757	Soper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Steven A. Soper (Baton Rouge, Louisiana); Francis Barany (New York, New York); Sunggook Park (Baton Rouge, Louisiana); Michael Murphy (Baton Rouge, Louisiana); Collin J. McKinney (Durham, North Carolina); John William Efcavitch (San Carlos, California); Mateusz Hupert (Chapel Hill, North Carolina)
ABSTRACT	The present invention is directed to methods comprising a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The nanotubes have a passage extending between an input end proximate to the bioreactor chamber and an output end distal to the bioreactor chamber, and comprises one or more nanopores within the passage with each nanopore having a reduced diameter relative to the passage.
FILED	Wednesday, July 17, 2019
APPL NO	16/513947
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0645 (20130101) B01L 2300/0861 (20130101) B01L 2300/0896 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/40 (20130101) C12M 23/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2561/125 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class
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10830758 — Systems and methods enabling patch-clamp re-use

US 10830758	Kolb et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Ilya Kolb (Atlanta, Georgia); William Stoy (Atlanta, Georgia); Erin Rousseau (Clifton Park, New York); Craig R. Forest (Atlanta, Georgia)
ABSTRACT	A method for cleaning patch-clamp glass pipette electrodes that enables their re-use. By immersing pipette tips or planar patch clamp chips into a detergent, followed by rinsing, pipettes and planar patch clamp chips were re-usable at least ten times with little to no degradation in signal fidelity, in experimental preparations ranging from human embryonic kidney cells to neurons in culture, slices, and in vivo.
FILED	Tuesday, August 09, 2016
APPL NO	15/232770
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/022 (20130101) B01L 13/00 (20190801) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48728 (20130101) Original (OR) Class
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10830774 — Methods and compositions for diagnosis and treatment of meningitis

US 10830774	Barnum et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	UAB Research Foundation (Birmingham, Alabama)
ASSIGNEE(S)	UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S)	Scott R. Barnum (Birmingham, Alabama); Theresa N. Schein (Birmingham, Alabama); James M. Johnston (Birmingham, Alabama)
ABSTRACT	The present invention provides a method of identifying meningitis as either bacterial meningitis or aseptic meningitis in a subject, comprising: a) measuring the amount of complement C3, complement factor B, complement membrane attack complex (MAC) protein, complement C5b, complement C6, complement C7, complement C8, and/or complement C9 in a cerebrospinal fluid (CSF) sample obtained from the subject; and b) comparing the amount of complement C3, complement factor B, complement MAC protein, complement C5b, complement C6, complement C7, complement C8, and/or complement C9 measured in (a) with the amount of complement C3, complement factor B, complement MAC protein, complement C5b, complement C6, complement C7, complement C8, and/or complement C9 measured in a control sample, wherein an amount of complement C3, complement factor B, complement MAC protein, complement C5b, complement C6, complement C7, complement C8, and/or complement C9 measured in (a) that is greater than the amount of complement C3, complement factor B, complement MAC protein, complement C5b, complement C6, complement C7, complement C8, and/or complement C9 measured in the control sample identifies the meningitis in the subject as bacterial meningitis.
FILED	Monday, March 27, 2017
APPL NO	15/469986
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/56911 (20130101) G01N 2333/195 (20130101) G01N 2333/4716 (20130101) G01N 2800/26 (20130101) G01N 2800/28 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101)
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10830775 — Tau kinetic measurements

US 10830775	Bateman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Randall Bateman (St. Louis, Missouri); Chihiro Sato (St. Louis, Missouri); Kwasi Mawuenyega (St. Louis, Missouri); Tim Miller (St. Louis, Missouri); David Holtzman (St. Louis, Missouri)
ABSTRACT	The invention relates to in vitro methods for measuring the in vivo metabolism of tau in a subject.
FILED	Wednesday, September 30, 2015
APPL NO	15/515909
ART UNIT	1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 51/08 (20130101) A61K 2039/505 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/6896 (20130101) Original (OR) Class
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10830851 — Methods for spatially encoding magnetic resonance signals with swept radio frequency (RF) pulses applied with RF spatial phase gradients

US 10830851	Wald et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Lawrence L. Wald (Cambridge, Massachusetts); Clarissa Z. Cooley (South Boston, Massachusetts); Jason Stockmann (Cambridge, Massachusetts); Bastien Guerin (Cambridge, Massachusetts); Matthew Rosen (Somerville, Massachusetts)
ABSTRACT	Described here are systems and methods for performing magnetic resonance imaging (“MRI”) using radio frequency (“RF”) phase gradients to provide spatial encoding of magnetic resonance signals rather than the conventional magnetic field gradients. Particularly, the systems and methods described here implement swept RF pulses (e.g., wideband, uniform rate, and smooth transition (“WURST”) RF pulses) and a quadratic phase correction to enable RF phase gradient encoding in inhomogeneous background (B₀) magnetic fields.
FILED	Tuesday, April 11, 2017
APPL NO	16/092686
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/482 (20130101) G01R 33/4822 (20130101) G01R 33/4831 (20130101) Original (OR) Class G01R 33/5608 (20130101) G01R 33/5617 (20130101)
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10830853 — Simultaneous proton resonance frequency shift thermometry and T₁measurements using a single reference variable flip angle T₁method

US 10830853	Svedin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) NIH Office of the Director (NIHOD)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	Siemens Healthcare GmbH (Erlangen, Germany); University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Bryant Svedin (West Jordan, Utah); Dennis L. Parker (Centerville, Utah); Allison Payne (Salt Lake City, Utah)
ABSTRACT	A computer implemented method for measuring T₁in an anatomical region of interest during a dynamic procedure includes acquiring a reference MR image of the anatomical region of interest using a first flip angle. A first set of dynamic MR images of the anatomical region of interest are acquired using a second flip angle. The reference MR image and the first set are used to calculate a reference T₁value for tissue in the anatomical region of interest. During an intervention where the T₁value may change, a second set of dynamic MR images of the anatomical region of interest is acquired using the second flip angle. The reference MR image and the second set are used to calculate an estimated T₁value. The reference T₁value, the estimated T₁value, and the first and second flip angles may then be used to correct the estimated T₁value.
FILED	Friday, April 19, 2019
APPL NO	16/388931
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/5615 (20130101) Original (OR) Class
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10830855 — Free-breathing cine DENSE imaging

US 10830855	Cai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Xiaoying Cai (Charlottesville, Virginia); Frederick H. Epstein (Charlottesville, Virginia)
ABSTRACT	In some aspects, the disclosed technology relates to free-breathing cine DENSE (displacement encoding with stimulated echoes) imaging. In some embodiments, self-gated free-breathing adaptive acquisition reduces free-breathing artifacts by minimizing the residual energy of the phase-cycled T1-relaxation signal, and the acquisition of the k-space data is adaptively repeated with the highest residual T1-echo energy. In some embodiments, phase-cycled spiral interleaves are identified at matched respiratory phases by minimizing the residual signal due to T1 relaxation after phase-cycling subtraction; image-based navigators (iNAVs) are reconstructed from matched phase-cycled interleaves that are comprised of the stimulated echo iNAVs (ste-iNAVs), wherein the ste-iNAVs are used for motion estimation and compensation of k-space data.
FILED	Thursday, March 28, 2019
APPL NO	16/368218
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/7203 (20130101) A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5673 (20130101) G01R 33/56509 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/50 (20130101) G06T 7/0014 (20130101) G06T 7/20 (20130101) G06T 11/005 (20130101) G06T 11/008 (20130101) G06T 2207/10088 (20130101) G06T 2207/20224 (20130101) G06T 2207/30048 (20130101) G06T 2211/424 (20130101)
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10831014 — Systems and methods for three dimensional imaging

US 10831014	Hillman
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Elizabeth M. C. Hillman (New York, New York)
ABSTRACT	Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed.
FILED	Monday, July 23, 2018
APPL NO	16/042700
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101)
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10832403 — Systems, methods, and apparatuses for generating regions of interest from voxel mode based thresholds

US 10832403	Van Breugel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S)	KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S)	Johanna Van Breugel (Cambridge, Massachusetts); Aaron Abajian (Cambridge, Massachusetts); John Treilhard (Cambridge, Massachusetts); Susanne Smolka (Cambridge, Massachusetts); Julius Chapiro (Berlin, Germany); James Duncan (Cambridbe, Massachusetts); MingDe Lin (New Haven, Connecticut)
ABSTRACT	The described implementations relate to systems, methods, and apparatuses for generating regions of interest (214) from imaging data (212). Specifically, the regions of interest are generated for tracking treatment efficacy in a more consistent and repeatable manner. The regions of interest can be generated from contrast medium and non-contrast medium enhanced scans (102) of a patient. Voxel data derived from the scans can be collected and distributed according to respective intensity values in order to identify mode voxels (116, 118, 120) for particular ranges (128) of intensities. Regions of interest (110, 112, 114) can then be generated for each identified mode voxel, and standard deviations for the regions of interest can be determined. One or more thresholds can be derived from the determined standard deviations in order to further filter the intensity values and identify filtered groups of voxels to be the resulting regions of interest.
FILED	Monday, May 14, 2018
APPL NO	15/978904
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 15/08 (20130101) G06T 2207/30096 (20130101)
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10832795 — Compressed sensing for simultaneous measurement of multiple different biological molecule types in a sample

US 10832795	Sachs et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Board of Trustees of the Leland Standford Junior University (Palo Alto, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S)	Karen Sachs (Palo Alto, California); Mohammed N. AlQuraishi (Cambridge, Massachusetts); Solomon Itani (Vallejo, California); Garry P. Nolan (Menlo Park, California); Sean C. Bendall (San Mateo, California); Tyler J. Burns (Stanford, California)
ABSTRACT	A method and apparatus for simultaneously determining multiple different biological molecule types in a sample include labeling each different biological molecule type in a biological sample with a unique combination of a plurality of labels. Each different biological molecule type is selected from a population of M different biological molecules types. The plurality of labels is selected from a population of L different labels; and, M is greater than L. Measurements are obtained of relative abundances of the L different labels in the sample. Relative abundance of up to M different biological molecule types in the sample are determined based on the measurements and a method of compressed sensing.
FILED	Wednesday, March 22, 2017
APPL NO	15/466329
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 15/1425 (20130101) G01N 33/4915 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Original (OR) Class
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10833570 — Homopolar bearingless slice motors

US 10833570	Noh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Minkyun Noh (Cambridge, Massachusetts); David L. Trumper (Plaistow, New Hampshire)
ABSTRACT	Described are homopolar bearingless slice motors which include an array arrangement of permanent magnets on stator teeth, and a magnet-free rotor having a unique surface geometry. Also described are related components of such motors. The permanent magnet arrays provide homopolar bias flux to the rotor, and salient features on the rotor surface route the bias flux toward paths desirable for force and torque generation. In an illustrative embodiment, two magnet arrays are placed at the tips of stator teeth, so as to provide the bias flux via relatively short flux paths. By modulating current through windings based upon the rotor radial and angular position measurements, the stator can levitate and rotate the rotor.
FILED	Thursday, November 29, 2018
APPL NO	16/204042
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Dynamo-electric Machines H02K 1/17 (20130101) H02K 1/246 (20130101) H02K 7/09 (20130101) H02K 11/215 (20160101) H02K 19/103 (20130101) H02K 21/20 (20130101) Original (OR) Class H02K 21/44 (20130101)
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10833725 — Methods, systems, and articles of manufacture for joint decoding of packets in wireless networks using chirp spread-spectrum modulation

US 10833725	Dongare et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Adwait Dongare (Pittsburgh, Pennsylvania); Artur Balanuta (Pittsburgh, Pennsylvania); Akshay Gadre (Pittsburgh, Pennsylvania); Robert Iannucci (Palo Alto, California); Swarun Kumar (Pittsburgh, Pennsylvania); Anh Luong (Pittsburgh, Pennsylvania); Revathy Narayanan (Chennai, India); Anthony Rowe (Pittsburgh, North Carolina)
ABSTRACT	A method of providing wireless communications in a wireless network can include wirelessly receiving a chirp spread-spectrum modulated signal at a first gateway device, the chirp spread-spectrum modulated signal being transmitted by a remote client device. The chirp spread-spectrum modulated signal can be demodulated at the first gateway device to provide demodulated data at the first gateway device. The demodulated data can be processed to provide an indication that a decode of a packet including the demodulated data failed. Time adjacent chirps included in the demodulated data can be combined to provide combined data at the first gateway device. A message can be transmitted from the first gateway device to a remote server responsive to an amplitude of the combined data exceeding a threshold value and the indication that the decode of the packet including the demodulated data failed.
FILED	Tuesday, June 02, 2020
APPL NO	16/890102
ART UNIT	2632 — Digital Communications
CURRENT CPC	Demodulation or Transference of Modulation From One Carrier to Another H03D 3/009 (20130101) Transmission H04B 1/12 (20130101) H04B 1/7102 (20130101) Original (OR) Class H04B 2001/6912 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/364 (20130101) H04L 27/3818 (20130101)
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Department of Defense (DOD)

10827911 — Optical imaging system employing vortex fiber for multiple-mode illumination

US 10827911	Ramachandran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
INVENTOR(S)	Siddharth Ramachandran (Boston, Massachusetts); Lu Yan (Sunnyvale, California); Poul Kristensen (Valby, Denmark)
ABSTRACT	A vortex optical fiber for use in an illumination subsystem of an optical imaging system (e.g., a stimulated emission depletion (STED) microscopy system) includes an elongated optically transmissive medium having a set of regions including a core region, a trench region surrounding the core region, a ring region surrounding the trench region, and a cladding region, the set of regions having a doping profile providing a Δn_efffor vector modes in an LP₁₁mode group of greater than 1×10⁻⁴in the visible spectral range so as to simultaneously guide stable Gaussian and orbital angular momentum (OAM) carrying modes at corresponding visible wavelengths.
FILED	Monday, June 05, 2017
APPL NO	16/306026
ART UNIT	2874 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0017 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/0286 (20130101) G02B 6/02071 (20130101) G02B 6/02195 (20130101) G02B 6/02366 (20130101) G02B 6/02395 (20130101) G02B 6/03644 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) G02B 27/58 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/094 (20130101)
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10828323 — Topical compositions and methods of using the same

US 10828323	Doxey et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Novan, Inc. (Morrisville, North Carolina)
ASSIGNEE(S)	Novan, Inc. (Morrisville, North Carolina)
INVENTOR(S)	Ryan Doxey (Raleigh, North Carolina); Jian Bao (Cary, North Carolina)
ABSTRACT	The present invention generally relates to topical compositions and methods of using the same. The topical compositions may comprise a hydrophilic composition and a hydrophobic composition in admixture. The hydrophobic composition may include a nitric oxide-releasing compound such as, for example, a diazeniumdiolate functionalized co-condensed silica particle. In some embodiments, the topical composition may be self-emulsifying. Further described herein are kits comprising a hydrophilic composition and a hydrophobic composition.
FILED	Friday, January 18, 2019
APPL NO	16/251972
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/25 (20130101) A61K 8/042 (20130101) A61K 8/345 (20130101) A61K 8/898 (20130101) A61K 9/06 (20130101) A61K 9/10 (20130101) A61K 9/0014 (20130101) A61K 9/107 (20130101) A61K 33/00 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) A61K 47/44 (20130101) A61K 47/52 (20170801) A61K 47/59 (20170801) A61K 2800/22 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/005 (20130101) A61Q 19/00 (20130101)
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10828334 — Mesenchymal stem cells and uses therefor

US 10828334	Aggarwal et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Mesoblast International Sárl (Meyrin, Switzerland)
ASSIGNEE(S)	Mesoblast International Sárl (Meyrin, Switzerland)
INVENTOR(S)	Sudeepta Aggarwal (North Potomac, Maryland); Mark F. Pittenger (Severna Park, Maryland); Timothy Varney (Baltimore, Maryland)
ABSTRACT	Compositions and methods of promoting wound healing in a human by administering to the human mesenchymal stem cells in an effective amount.
FILED	Wednesday, March 11, 2020
APPL NO	16/815784
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/2026 (20130101) A61K 38/2066 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0664 (20130101) C12N 5/0665 (20130101) C12N 5/0666 (20130101) C12N 5/0667 (20130101) C12N 5/0668 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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10828398 — Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use

US 10828398	Jiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Shaoyi Jiang (Redmond, Washington); Tao Bai (Seattle, Washington); Harihara Subramanian Sundaram (Seattle, Washington); Andrew William Sinclair (Seattle, Washington); Jean-René Ella-Menye (Seattle, Washington); Priyesh Jain (Seattle, Washington)
ABSTRACT	Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
FILED	Monday, April 29, 2019
APPL NO	16/398002
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 47/58 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/24 (20130101) A61L 15/42 (20130101) A61L 24/0031 (20130101) A61L 24/046 (20130101) A61L 27/16 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/021 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 2533/30 (20130101) C12N 2539/00 (20130101)
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10828446 — Insulated endotracheal devices and systems for transpulmonary thermal transfer

US 10828446	Kumar et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Mayo Foundation For Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Matthew M. Kumar (Austin, Minnesota); Larry Dale Johnson (Red Wing, Minnesota)
ABSTRACT	Endotracheal devices, systems, and methods of using the same for transpulmonary thermal transfer to, e.g., induce transpulmonary hypothermia and/or warming. The endotracheal devices may include first and second lumens extending through the endotracheal device along with insulation located in an interior of the tube of the endotracheal device to limit thermal energy transfer between fluids in the first and second lumens.
FILED	Friday, September 12, 2014
APPL NO	15/021138
ART UNIT	3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2018/00101 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/12 (20130101) A61F 2007/0063 (20130101) A61F 2007/0069 (20130101) A61F 2007/0091 (20130101) A61F 2007/126 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 16/14 (20130101) A61M 16/042 (20140204) A61M 16/208 (20130101) A61M 16/0434 (20130101) A61M 16/0463 (20130101) A61M 16/0486 (20140204) Original (OR) Class A61M 16/1075 (20130101) A61M 2205/3368 (20130101) A61M 2205/3633 (20130101)
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10828522 — Neutralization method using reactive energetic materials

US 10828522	Rohman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Armament Research, Development and Engineering Center (ARDEC) Office of the Secretary of Defense (OSD) DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S)	MATSYS INC. (Sterling, Virginia)
ASSIGNEE(S)	MATSYS INC. (Sterling, Virginia)
INVENTOR(S)	Stephen Rohman (Purcellville, Virginia); Tony F. Zahrah (Fairfax Station, Virginia); Pascal Dubé (Aldie, Virginia)
ABSTRACT	Formulations of reactive materials, such as aluminum, magnesium and alloys thereof, with combustible additives such as wood derivatives or charcoal, provide a composition for neutralizing energetic materials via combustion. Specifically, explosive substances such as ammonium nitrate and urea nitrate, which are commonly used as homemade explosives, are rapidly incinerated in a non-propagating manner by the contact with burning reactive material formulations.
FILED	Tuesday, April 23, 2019
APPL NO	16/391844
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/38 (20130101) Original (OR) Class A62D 2101/06 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/04 (20130101) B22F 2009/041 (20130101) B22F 2301/30 (20130101) B22F 2301/40 (20130101) B22F 2301/052 (20130101) B22F 2301/058 (20130101) B22F 2301/155 (20130101) B22F 2301/205 (20130101) B22F 2301/355 (20130101) B22F 2303/00 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101)
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10828618 — Alkali source and/or sink using ion-conducting solid electrolyte and mixed ion-electron conductor electrode

US 10828618	Roper et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Christopher S. Roper (Oak Park, California); Jason A. Graetz (Calabasas, California)
ABSTRACT	Some variations provide an alkali metal or alkaline earth metal atom source (e.g., vapor cell) with a solid ionic conductor and a mixed ion-electron conductor electrode. Mixed ion-electron conductor electrodes are used as efficient sources and/or as sinks for alkali metal or alkaline earth metal atoms, thus enabling electrical control over metal atom content in the vapor cell. Some variations provide a vapor-cell system comprising: a vapor-cell region configured to allow a vapor-cell optical path into a vapor-cell vapor phase; a first electrode containing an mixed ion-electron conductor that is conductive for an ion of at least one element selected from Rb, Cs, Na, K, or Sr; a second electrode electrically isolated from the first electrode; and an ion-conducting layer between the first electrode and the second electrode. The ion-conducting layer is ionically conductive for at least one ionic species selected from Rb⁺, Cs⁺, Na⁺, K⁺, or Sr²⁺.
FILED	Monday, December 11, 2017
APPL NO	15/837346
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) Original (OR) Class B01J 2219/0809 (20130101) B01J 2219/0871 (20130101) B01J 2219/0884 (20130101) Time-interval Measuring G04F 5/14 (20130101)
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10828663 — Conductive fiber composites containing multi-scale high conductive particles and methods

US 10828663	Wang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Shaokai Wang (Tallahassee, Florida); Zhiyong (Richard) Liang (Tallahassee, Florida)
ABSTRACT	Composite materials are provided that include a host material, nanoscale high conductive particles, and microscale high conductive particles. The nanoscale high conductive particles and the microscale high conductive particles may increase the through thickness thermal conductivity of the composite material by at least 4.0 W/(m·K), as compared to the same composite material without the nanoscale high conductive particles and microscale high conductive particles. Methods for making the composite materials herein also are provided.
FILED	Thursday, February 01, 2018
APPL NO	15/886139
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/12 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/26 (20130101) B32B 2250/20 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/106 (20130101) B32B 2264/105 (20130101) B32B 2307/30 (20130101) B32B 2307/54 (20130101) B32B 2307/72 (20130101) B32B 2307/302 (20130101) B32B 2307/732 (20130101) B32B 2571/02 (20130101) B32B 2605/18 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/06 (20130101) C08J 5/10 (20130101) C08J 5/042 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/83 (20130101) D06M 23/08 (20130101) D06M 2101/40 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101)
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10828665 — Methods and systems for deposition of blended polymer films

US 10828665	Stiff-Roberts et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Adrienne D. Stiff-Roberts (Durham, North Carolina); Ryan D. McCormick (Durham, North Carolina)
ABSTRACT	Methods and systems for deposition of blended polymer films are disclosed. According to an aspect a method of producing a film on a substrate includes combining a guest material, a host matrix, and a solvent having one or more hydroxyl (O—H) bonds to form a target emulsion. The method also includes exposing the target emulsion to an infrared source that is tuned to an absorption peak in the host matrix that is reduced in or absent from the guest material thereby desorbing the host matrix from the target emulsion and lifting the guest material from the surface of the target emulsion. The target emulsion and the substrate are oriented with respect to each other such that the lifted guest material is deposited as a film upon the substrate.
FILED	Friday, September 04, 2015
APPL NO	15/507290
ART UNIT	1796 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0815 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/002 (20130101) B05D 1/60 (20130101) B05D 3/06 (20130101) Original (OR) Class B05D 3/0218 (20130101) B05D 2201/02 (20130101) B05D 2401/10 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/12 (20130101) C23C 14/28 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1643 (20130101)
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10828754 — Fastener dispenser and presentation via removable magazine

US 10828754	Wymore et al.
FUNDED BY	Department of Defense (DOD) Missile Defense Agency (MDA)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Jacob L. Wymore (Huntsville, Alabama); Brian Bartlett (Owens Cross Roads, Alabama)
ABSTRACT	A fastener dispenser tool for kitting and dispensing a plurality of fasteners comprises a retention section, a presentation section extending from the retention section, and a retention slot extending along the retention section and the presentation section. The retention slot is operable to retain the plurality of fasteners for dispensing therefore. A presentation slot extends along the presentation section and is sized to receive a tool bit engageable with a lead fastener. The retention slot and presentation slot are sized, such that the plurality of fasteners are each slidable through the retention slot along the presentation section to facilitate dispensing of the lead fastener from the presentation section. The presentation section can be formed at a curve relative to the retention section, to provide clearance of retained fasteners from hardware being fastened by the lead fastener. Associated systems and methods are provided.
FILED	Monday, September 24, 2018
APPL NO	16/140208
ART UNIT	3651 — Material and Article Handling
CURRENT CPC	Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 23/06 (20130101) Original (OR) Class Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 27/00 (20130101)
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10828873 — Textile composite having sorptive and reactive properties against toxic agents

US 10828873	Anderson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Defense Technical Information Center (DTIC)
APPLICANT(S)	Battelle Memorial Institute (Columbus, Ohio); Guild Associates Inc. (Dublin, Ohio); The United States Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S)	Battelle Memorial Institute (Columbus, Ohio); Guild Associates Inc. (Dublin, Ohio); The United States Government as Represented by the Secretary of the Army (Natick, Massachusetts)
INVENTOR(S)	Erin Anderson (Milford, Massachusetts); Rachel Rossin (Ashville, Ohio); Joseph Rossin (Columbus, Ohio); Michael Knapke (Plain City, Ohio); Natalie Pomerantz (Newton, Massachusetts)
ABSTRACT	The present invention relates to a textile composite for the adsorption and breakdown of harmful chemical materials. A support layer and a sorptive and reactive material mounted on the support layer form a protective layer, which is mounted on an inner liner. The protective layer adsorbs and breaks down harmful chemical materials. An outer shell is formed of fabric having an outer surface that is hydrophobic for resisting the passage of harmful chemicals, which may be in the form of vapor, liquid or aerosols. Preferably, the sorptive and reactive material includes zirconium hydroxide, and the support layer includes a fabric material. The zirconium hydroxide is distributed on the fabric material in the amount of at least 20 grams of zirconium hydroxide per square meter. Alternatively, the zirconium hydroxide is distributed in the amount of at least 150 or 200 grams of zirconium hydroxide per square meter.
FILED	Friday, August 16, 2019
APPL NO	16/542599
ART UNIT	1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/26 (20130101) B32B 7/12 (20130101) B32B 19/06 (20130101) Original (OR) Class B32B 2255/02 (20130101) B32B 2264/102 (20130101) B32B 2307/7242 (20130101) B32B 2307/7265 (20130101)
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10829381 — Borophenes, boron layer allotropes and methods of preparation

US 10829381	Hersam et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois)
ABSTRACT	A method of preparing an atomically-dimensioned elemental boron allotrope includes providing a substrate at a temperature greater than about 200° C.; generating elemental boron vapor from a solid elemental boron source; and contacting said substrate with said boron vapor for at least one of a rate and at a pressure sufficient to deposit on said substrate a boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension, said method under negative pressure.
FILED	Friday, May 29, 2020
APPL NO	16/886936
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101)
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10829386 — Methods for making hydrothermally crystallized water-dispersible hexaferrite platelets

US 10829386	Gross et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Adam F. Gross (Santa Monica, California); Xin N. Guan (Monterey Park, California); Shanying Cui (Calabasas, California); Florian G. Herrault (Agoura Hills, California)
ABSTRACT	Some variations provide a method of making water-dispersed hexaferrite nanoparticles, comprising: providing a first salt containing iron, a second salt containing barium and/or strontium, and a third salt containing an anion or cation that is capable of forming a ligand with the hexaferrite nanoparticles; combining the first salt, second salt, third salt, and water to form a reaction mixture; subjecting the reaction mixture to effective reaction conditions to produce hexaferrite nanoparticles with the anion or cation in the third salt forming a ligand on the surface, so that the hexaferrite nanoparticles are dissolved and/or suspended in the reaction mixture; and obtaining water-dispersed hexaferrite nanoparticles with an average zeta potential of at least ±20 mV. The water-dispersed hexaferrite nanoparticles have a hexaferrite content of at least 85 wt %. The method may further include assembling water-dispersed hexaferrite nanoparticles into a magnetic component, such as a self-biased hexaferrite film on a semiconductor substrate.
FILED	Thursday, November 29, 2018
APPL NO	16/203788
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0036 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/24 (20130101) C01P 2004/64 (20130101) C01P 2006/22 (20130101) C01P 2006/40 (20130101) C01P 2006/42 (20130101)
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10829420 — Filamentous organism-derived carbon-based materials, and methods of making and using same

US 10829420	Ren et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL) Office of Naval Research (ONR)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado); The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Zhiyong Ren (Superior, Colorado); Mitchell Tyler Huggins (Boulder, Colorado); Justin C. Biffinger (Dayton, Ohio); Corey T. Love (Alexandria, Virginia); Se-Hee Lee (Superior, Colorado); Justin M. Whiteley (Chicago, Illinois)
ABSTRACT	The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.
FILED	Friday, July 21, 2017
APPL NO	16/319734
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) C01B 32/20 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/83 (20130101) Original (OR) Class C04B 35/62655 (20130101) C04B 2235/422 (20130101) C04B 2235/428 (20130101) C04B 2235/604 (20130101) C04B 2235/606 (20130101) C04B 2235/3275 (20130101) C04B 2235/3418 (20130101) C04B 2235/5248 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/02 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/26 (20130101) H01G 11/32 (20130101) H01G 11/34 (20130101) H01G 11/40 (20130101) H01G 11/44 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/02 (20130101) H01M 4/133 (20130101) H01M 4/362 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/0568 (20130101) H01M 2300/0037 (20130101) H01M 2300/0068 (20130101)
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10829820 — Methods for molecularly characterizing cervical cell samples

US 10829820	Shen-Gunther
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC)
APPLICANT(S)	The United States Government as represented by the Secretary of the Army (Fort Detrick, Maryland)
ASSIGNEE(S)	The United States Government as represented by the Secretary of the Army (Fort Detrick, Maryland)
INVENTOR(S)	Jane Shen-Gunther (San Antonio, Texas)
ABSTRACT	Disclosed herein are methods for molecularly characterizing cervical cell samples as being negative for intraepithelial lesion or malignancy (NILM), low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL).
FILED	Tuesday, August 30, 2016
APPL NO	15/741891
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/708 (20130101) C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/154 (20130101)
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10830081 — Non-contact seal with non-straight spring beam(s)

US 10830081	Chuong et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Conway Chuong (Manchester, Connecticut); Tara L. D'Ambruoso (Oxford, Connecticut); Dwayne K. Mecklenburg (Stafford Springs, Connecticut); Peter E. Gunderson (West Hartford, Connecticut); Eric D. Gray (Glastonbury, Connecticut)
ABSTRACT	An assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. The seal shoes are arranged around an axis in an annular array. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes to the seal base. A first of the spring elements includes a first mount, a second mount and a spring beam. The first mount is connected to the first seal shoe. The second mount is connected to the seal base and disposed a circumferential distance away from the first mount. The spring beam extends longitudinally along a non-straight centerline between and connected to the first mount and the second mount.
FILED	Monday, July 17, 2017
APPL NO	15/651261
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/025 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/60 (20130101) F05D 2260/38 (20130101) Pistons; Cylinders; Sealings F16J 15/442 (20130101)
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10830092 — Bearing rotor thrust control

US 10830092	Snow et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Contract Management Agency (DCMA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Kyle Robert Snow (Loveland, Ohio); Andrew Michael Tompkins (Cincinnati, Ohio); Andrew Michael Watson (Cincinnati, Ohio); Philip Joseph Ogston (Cincinnati, Ohio); Christopher Michael Thompson (West Chester, Ohio)
ABSTRACT	Rotor thrust balancing systems for turbomachines and methods of using the same are generally disclosed. For example, a rotor thrust balancing system for a turbomachine, wherein the turbomachine defines a centerline extending the length of the turbomachine. The system includes a rotating drive shaft, a thrust bearing, and a first waveguide sensor. The rotating drive shaft couples a turbine section and a compressor section of the turbomachine. The thrust bearing supports the rotating drive shaft of the turbomachine. The thrust bearing includes a plurality of ball bearings, an inner race coupled to the rotating drive shaft, and an outer race coupled to a fixed structure. The first waveguide sensor is coupled to the outer race at a first end of the waveguide sensor. The waveguide sensor communicates a vibrational frequency from the thrust bearing to a second end of the waveguide sensor.
FILED	Wednesday, March 07, 2018
APPL NO	15/914419
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 3/04 (20130101) F01D 21/003 (20130101) F01D 21/14 (20130101) Original (OR) Class F01D 25/16 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/52 (20130101) F05D 2260/15 (20130101) F05D 2270/54 (20130101) F05D 2270/334 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 19/02 (20130101) F16C 19/10 (20130101) F16C 19/163 (20130101) F16C 19/522 (20130101) F16C 19/527 (20130101) F16C 2233/00 (20130101) F16C 2326/43 (20130101) F16C 2360/23 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/0019 (20130101) G01L 19/12 (20130101)
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10830096 — Rotating turbine vane bearing cooling

US 10830096	Slavens et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Thomas N. Slavens (Vernon, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut)
ABSTRACT	A pivoting turbine vane has an airfoil, an inner bearing race and an outer bearing race, with the inner and outer bearing races on a pivot axis of the pivoting turbine vane. There are cooling air passages through at least one of the inner and outer bearing races to provide cooling air from a remote facing face of at least one of the inner and outer bearing races to an airfoil facing face of at least one of the inner and outer bearing races. A turbine section is also disclosed.
FILED	Monday, September 22, 2014
APPL NO	14/917434
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 9/041 (20130101) F01D 17/14 (20130101) F01D 17/162 (20130101) F01D 25/16 (20130101) F01D 25/125 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/81 (20130101) F05D 2250/38 (20130101) F05D 2250/314 (20130101) F05D 2260/20 (20130101) F05D 2260/2212 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101)
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10830322 — Rotary positioning apparatus for an aimed device

US 10830322	Sasso
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	THE AEROSPACE CORPORATION (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Felix T. Sasso (Los Angeles, California)
ABSTRACT	A rotary positioning apparatus can adjust the rotational position of a device to be aimed about a desired axis. It can include an device mount that includes the aimed device. A motor can be coupled to the device mount or a shaft extending from the device mount to generate a rotational force to rotate the device mount. Primary mechanical flexures can be positioned along opposing ends of the device mount to provide a mechanical resistance to the rotation imparted on the device mount by the motor. A brake system can be included to stop rotation of the device mount with or without the motor engaged. Secondary mechanical flexures can be coupled to each of the primary mechanical flexures and constructed of materials that give it a lower torque resistance so that the secondary mechanical flexures can begin rotating before the primary mechanical flexures to provide small angle adjustability.
FILED	Thursday, June 13, 2019
APPL NO	16/440336
ART UNIT	3656 — Material and Article Handling
CURRENT CPC	Gearing F16H 35/18 (20130101) Original (OR) Class
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10830372 — Pneumatic controllers, pneumatically controlled inline valves, and methods of cooling pneumatic controllers

US 10830372	DeFelice et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Life Cycle Management Center (AFLCMC)
APPLICANT(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S)	HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S)	Robert DeFelice (South Windsor, Connecticut); Peter J. Dowd (Granby, Connecticut)
ABSTRACT	A pneumatic controller includes a manifold, a selector, and a biasing member. The manifold has a low pressure port, a high pressure port, an actuator port, and a vent. The selector is movable within the manifold between a first position and a second position, the low pressure port in fluid communication with the actuator port in the first position, the high pressure port in fluid communication with the actuator port in the second position. The biasing member is supported within the manifold and urges the selector towards the first position, wherein the low pressure port is in fluid communication with the vent in both the first position and the second position to cool the biasing member with low pressure fluid received at the low pressure port. Inline valves, gas turbine engines, and methods of controlling fluid flow through inline valves are also described.
FILED	Thursday, June 20, 2019
APPL NO	16/447786
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/126 (20130101) F16K 31/1223 (20130101) Original (OR) Class F16K 31/1226 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) Y10T 137/3421 (20150401) Y10T 137/3476 (20150401)
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10830374 — Biasing cryogenic feedline installations to eliminate braided hose distortions and extend useful life of braided hoses

US 10830374	Di Carlo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Tony Di Carlo (Long Beach, California); Richard Topf (Orange, California)
ABSTRACT	The present disclosure relates to the construction and use of feedlines in temperature-biased systems that include counter-biased hoses. The alignment and installation/uninstallation of the counter-biased hoses is enabled by a biasing tool with at least a first yoke having a first rotation point and a second rotation point, a second yoke having a third rotation point and a fourth rotation point, a first rod assembly connected to the first yoke at the first rotation point and connected to the second yoke at the fourth rotation point, and a second rod assembly connected to the first yoke at the second rotation point and connected to the second yoke at the third rotation point.
FILED	Friday, March 30, 2018
APPL NO	15/941629
ART UNIT	3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 3/105 (20130101) Original (OR) Class F16L 59/141 (20130101) F16L 59/153 (20130101)
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10830549 — Handle and firing mechanism assembly

US 10830549	Facteau et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Robert J. Facteau (Troy, New York); George E. Hathaway, IV (Watervliet, New York); Brett L. Stewart (Schenectady, New York); Zachary P. Jablonka (Niskayuna, New York)
ABSTRACT	A Handle and Firing Mechanism Assembly (H&FMA) provides a robust and streamlined H&FMA for a mortar weapon system. The H&FMA is easier to assemble and eliminates jamming issues, and firing pin protrusion adjustment procedures. It also incorporates a lighter trigger squeeze in Trigger fire mode and locks the firing pin in Drop fire mode. The handle is easier and more cost effective to produce. The H&FMA can be used with, for example, a 60 mm mortar weapon system.
FILED	Friday, June 07, 2019
APPL NO	16/434296
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 19/29 (20130101) Original (OR) Class Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 1/06 (20130101)
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10830578 — High-speed metrology

US 10830578	Weber et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Inkbit, LLC (Medford, Massachusetts)
ASSIGNEE(S)	Inkbit, LLC (Medford, Massachusetts)
INVENTOR(S)	Aaron Weber (Arlington, Massachusetts); Kiril Vidimce (Cambridge, Massachusetts); Walter H. Zengerle, III (Dedham, Massachusetts); Desai Chen (Arlington, Massachusetts); Wojciech Matusik (Lexington, Massachusetts)
ABSTRACT	A method and an apparatus are directed to characterizing a continuously moving 3D object via interferometry-based scanning. The method includes repeatedly forming several depth characterizations of the 3D object along respective scan lines of a plurality of scan lines on the surface of the 3D object. During this scanning, the 3D object is undergoing its continuous motion. The method further includes combining the determined depth characterization along the scan lines of the plurality of scan lines to form a depth map representing at least a depth of a portion associated with a location on the surface of the 3D object in the third direction on a grid of locations arranged in the first and second directions. Forming the depth characterizations includes scanning a frequency-dispersed pulsed optical signal in a first direction across the continuously moving 3D object, said 3D object moving in a second direction substantially orthogonal to the first direction. The scanned optical signal forming scan lines on a surface of the 3D object in a third direction substantially orthogonal to the first direction and the second direction.
FILED	Thursday, October 17, 2019
APPL NO	16/656060
ART UNIT	2886 — Optics
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02015 (20130101) G01B 11/22 (20130101) Original (OR) Class
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10830747 — System and method for predicting fatigue strength of alloys

US 10830747	Agrawal et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ankit Agrawal (Evanston, Illinois); Alok Choudhary (Chicago, Illinois)
ABSTRACT	Systems and methods include a predictor module configured to receive an input, e.g., composition parameters and processing parameters. A processor processes the input to predict a material property, e.g., fatigue strength, of an alloy based on the input. The processor outputs the predicted fatigue strength of the alloy for display.
FILED	Wednesday, October 25, 2017
APPL NO	15/793376
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/20 (20130101) G01N 33/202 (20190101) Original (OR) Class G01N 33/2022 (20190101) G01N 33/2025 (20190101) G01N 33/2028 (20190101) G01N 2203/0073 (20130101) G01N 2203/0218 (20130101) G01N 2203/0246 (20130101) Electric Digital Data Processing G06F 16/2465 (20190101) G06F 30/20 (20200101) G06F 30/333 (20200101)
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10830766 — Fibrous substrate and method for making

US 10830766	Singamaneni et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Srikanth Singamaneni (St. Louis, Missouri); Evan Kharasch (St. Louis, Missouri); Jeremiah Morrissey (St. Louis, Missouri); Chang Hee Lee (Tempe, Arizona)
ABSTRACT	Natural and/or synthetic antibodies for specific proteins are adhered to nanoparticles. The nanoparticles are adhered to a substrate and the substrate is exposed to a sample that may contain the specific proteins. The substrates are then tested with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the specific protein in the sample.
FILED	Friday, May 22, 2015
APPL NO	14/719972
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/658 (20130101) G01N 33/553 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 33/54373 (20130101) G01N 33/57438 (20130101) G01N 2201/02 (20130101)
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10830767 — Nanocomposites, methods of making same, and applications of same for multicolor surface enhanced raman spectroscopy (SERS) detections

US 10830767	Biris et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S)	Alexandru S. Biris (Little Rock, Arkansas); Zeid Nima (Little Rock, Arkansas); Yang Xu (Little Rock, Arkansas)
ABSTRACT	A method of making at least one nanocomposite for surface enhanced Raman spectroscopy (SERS) detection of a target of interest includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer, wherein the Raman reporter molecule layer comprises Raman reporter molecules that are detectable by the SERS; coating a thiolated polyethylene glycol (PEG) layer on the assembled Raman reporter molecule layer; and conjugating the coated thiolated PEG layer with molecules of an antibody to make the at least one nanocomposite.
FILED	Wednesday, September 06, 2017
APPL NO	15/697055
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/553 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 33/54353 (20130101)
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10830787 — Optical accelerometers for use in navigation grade environments

US 10830787	Challener et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	William Albert Challener (Glenville, New York); Mengli Wang (Rexford, New York)
ABSTRACT	An accelerometer includes a membrane, an energy source producing a laser beam which is directed at the membrane causing it to vibrate, and a transparent cap disposed at one end of the energy source. The accelerometer includes a first controller for adjusting an output power of the energy source in a first feedback loop, a second controller for controlling the wavelength of the laser beam in a second feedback loop, and a detector sensing a reflected portion of the laser beam. An acceleration signal is based in part on the frequency of the reflected portion of the laser beam.
FILED	Tuesday, May 01, 2018
APPL NO	15/968668
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) B81B 2201/0235 (20130101) B81B 2203/04 (20130101) B81B 2203/0127 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) Original (OR) Class G01P 15/097 (20130101) G01P 15/0802 (20130101) Optical Elements, Systems, or Apparatus G02B 26/02 (20130101)
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10830790 — Method and system of dual-mode actuation and sensing for real-time calibration of axisymmetric resonant gyroscopes

US 10830790	Shirazi et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corpoation (Atlanta, Georgia)
INVENTOR(S)	Arashk Norouz Pour Shirazi (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia)
ABSTRACT	A dual-mode actuation and sensing circuit actuates both modes of an axisymmetric gyroscope and senses both outputs thereof. The sum of the two outputs provides a self-sustaining closed-loop oscillation signal, while the difference of the two mode outputs is used for extracting differential rate information while rejecting the common-mode bias terms of the gyroscope to provide online bias calibration. The proposed system and method facilitates scale factor calibration of an axisymmetric gyroscope. Furthermore, the difference output of the dual-mode gyroscope can provide a mode-split indicator signal which can be used to automatically match the gyroscope modes.
FILED	Monday, January 28, 2019
APPL NO	16/259305
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5719 (20130101) G01C 19/5726 (20130101) G01C 19/5776 (20130101) G01C 25/00 (20130101) G01C 25/005 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) G01P 15/125 (20130101) G01P 21/00 (20130101) Original (OR) Class
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10830848 — System and method for low-field, multi-channel imaging

US 10830848	Rosen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Matthew S. Rosen (Somerville, Massachusetts); Lawrence L. Wald (Charlestown, Massachusetts); Cristen LaPierre (Woburn, Massachusetts)
ABSTRACT	A system and method for performing parallel magnetic resonance imaging (pMRI) process using a low-field magnetic resonance imaging (IfMRI) system includes a substrate configured to follow a contour of a portion of a subject to be imaged by the IfMRI system using a pMRI process. A plurality of coils are coupled to the substrate. Each coil in the plurality of coils has a number of turns and an associated decoupling mechanism selected to operate the plurality of coils to effectuate the pMRI process using the IfMRI system.
FILED	Friday, March 13, 2015
APPL NO	15/125514
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/365 (20130101) G01R 33/445 (20130101) G01R 33/3415 (20130101) G01R 33/3657 (20130101) Original (OR) Class G01R 33/5611 (20130101) G01R 33/5635 (20130101) G01R 33/5673 (20130101) G01R 33/34007 (20130101) G01R 33/34046 (20130101)
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10830890 — Multispectral LADAR using temporal dispersion

US 10830890	Keyser
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S)	Christian Keyser (Shalimar, Florida)
ABSTRACT	A LADAR that includes a transmitter and a receiver. The transmitter includes a laser for delivering an original beam pulse. A nonlinear optic receives the original beam pulse and outputs wavelengths as an incident beam pulse. Output optics direct the incident beam pulse onto a target, which reflect from the target as a reflected beam pulse. The receiver includes a dispersive optic for temporally dispersing the wavelengths in the reflected beam pulse, thereby producing a dispersed beam pulse. A single-pixel sensor receives the dispersed beam pulse, and measures and outputs a separate intensity value for each of the wavelengths in the dispersed beam pulse based at least in part on the temporal dispersion of the wavelengths. A processor receives the intensity values from the dispersed beam pulse, correlates the intensity values with the wavelengths, compares the intensity values to known intensity values from the incident beam pulse, produces ratio values for each of the wavelengths, and produces reflectance data in regard to the target from the ratio values.
FILED	Thursday, April 12, 2018
APPL NO	15/951697
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/1895 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4811 (20130101) G01S 7/4863 (20130101) G01S 17/89 (20130101) Original (OR) Class
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10830918 — Magneto-inductive transmitter with electrically modulated reluctance

US 10830918	Strachen et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Michigan)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Nathan Daniel Strachen (Madison, Wisconsin); Nader Behdad (Oregon, Wisconsin); John H. Booske (McFarland, Wisconsin)
ABSTRACT	A magneto-inductive transmit antenna is provided that includes a shield formed of a magnetic material, a magnetic field source mounted on a first side of the shield, and a coil wrapped around the shield to define a number of turns. The coil is configured to conduct a current therethrough. The magnetic material is configured to exhibit a change in permeability based on the current conducted through the coil when the current is conducted through the coil. The change in permeability is configured to modulate a magnetic field of the magnetic field source. The magnetic field is modulated relative to a second side of the shield opposite the first side when the permeability is changed.
FILED	Monday, July 09, 2018
APPL NO	16/030364
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/10 (20130101) G01V 3/088 (20130101) Original (OR) Class
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10830952 — Integrated photonics including germanium

US 10830952	Coolbaugh et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S)	Douglas Coolbaugh (Highland, New York); Thomas Adam (Slingerlands, New York); Gerald L. Leake (Delmar, New York)
ABSTRACT	A photonic structure can include in one aspect one or more waveguides formed by patterning of waveguiding material adapted to propagate light energy. Such waveguiding material may include one or more of silicon (single-, poly-, or non-crystalline) and silicon nitride.
FILED	Friday, April 26, 2019
APPL NO	16/396128
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) Original (OR) Class G02B 6/43 (20130101) G02B 6/132 (20130101) G02B 6/136 (20130101) G02B 6/1347 (20130101) G02B 6/12002 (20130101) G02B 2006/121 (20130101) G02B 2006/12061 (20130101) G02B 2006/12104 (20130101) G02B 2006/12123 (20130101) G02B 2006/12169 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0245 (20130101) H01L 21/0262 (20130101) H01L 21/2033 (20130101) H01L 21/2053 (20130101) H01L 21/02381 (20130101) H01L 21/02505 (20130101) H01L 21/02532 (20130101) H01L 21/02573 (20130101) H01L 21/02639 (20130101) H01L 27/14625 (20130101) H01L 27/14629 (20130101) H01L 31/028 (20130101) H01L 31/105 (20130101) H01L 31/0232 (20130101) H01L 31/1808 (20130101) H01L 31/02327 (20130101) H01L 31/022408 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101)
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10831014 — Systems and methods for three dimensional imaging

US 10831014	Hillman
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Elizabeth M. C. Hillman (New York, New York)
ABSTRACT	Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed.
FILED	Monday, July 23, 2018
APPL NO	16/042700
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101)
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10831533 — Reducing service downtime during service migration

US 10831533	Abali et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Bulent Abali (Tenafly, New Jersey); Hubertus Franke (Cortlandt Manor, New York); Thai Franck Le (White Plains, New York); Erich M. Nahum (New York, New York)
ABSTRACT	A computer-implemented method is provided for supporting virtual machine and/or container live migration. The method may include hosting a virtual machine (VM) at a first location to be migrated to a second location by sending VM data packets from the first location to the second location and detecting a predetermined event associated with the VM at the first location. The method may further include prompting, in response to detection of the predetermined event, the redirection of the VM data packets from the first location to a buffer associated with the second location and storing the VM data packets in the buffer. The method may further include detecting an end of the predetermined event associated with the first location, and redirecting, in response to the end of the predetermined event, the VM data packets stored in the buffer to the VM migrated to the second location.
FILED	Thursday, October 24, 2019
APPL NO	16/662464
ART UNIT	2445 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 9/544 (20130101) G06F 9/4856 (20130101) Original (OR) Class G06F 9/45558 (20130101) G06F 2009/4557 (20130101) G06F 2009/45595 (20130101)
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10831535 — Reducing minimum operating voltage through heterogeneous codes

US 10831535	Leng et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Jingwen Leng (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Pradip Bose (Yorktown Heights, New York); Ramon Bertran Monfort (New York, New York)
ABSTRACT	Preferred embodiments of systems and methods are disclosed to reduce a minimal working voltage, Vmin, and/or increase the frequency of Vmin while executing multithreaded computer programs with better reliability, efficiency, and performance. A computer complier complies multiple copies of high-level code, each with different a different set of resource allocators so system resources are allocated during simultaneous execution of multiple threads in a way that allows reducing Vmin at a given reference voltage frequency and/or increasing the frequency of Vmin at a given Vmin value.
FILED	Tuesday, January 01, 2019
APPL NO	16/237747
ART UNIT	2193 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 1/26 (20130101) G06F 8/41 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 9/5027 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101)
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10831543 — Contention-aware resource provisioning in heterogeneous processors

US 10831543	Chandramoorthy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Nandhini Chandramoorthy (Yorktown Heights, New York); Karthik V. Swaminathan (Mount Kisco, New York); Ramon Bertran Monfort (New York, New York); Alper Buyuktosunoglu (White Plains, New York); Pradip Bose (Yorktown Heights, New York)
ABSTRACT	Applications on different processing elements have different characteristics such as latency versus bandwidth sensitivity, memory level parallelism, different memory access patterns and the like. Interference between applications due to contention at different sources leads to different effects on performance and is quantified. A method for contention-aware resource provisioning in heterogeneous processors includes receiving stand-alone performance statistics for each processing element for a given application. Multi-core performance slowdown can be computed from the received stand-alone performance statistics. When a request to provision an application on the heterogeneous processors is received, application performance requirements of the application can be determined and a bandwidth for the application can be provisioned based on the application performance requirements and the computed multi-core performance slowdown parameter.
FILED	Friday, November 16, 2018
APPL NO	16/194252
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/48 (20130101) G06F 9/50 (20130101) G06F 9/4806 (20130101) G06F 9/4843 (20130101) G06F 9/4881 (20130101) G06F 9/5005 (20130101) G06F 9/5027 (20130101) Original (OR) Class
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10831595 — Performing error detection during deterministic program execution

US 10831595	Cassidy et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Air Force Research Laboratory (AFRL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Andrew S. Cassidy (San Jose, California); Dharmendra S. Modha (San Jose, California); John V. Arthur (Mountain View, California); Jun Sawada (Austin, Texas)
ABSTRACT	A computer-implemented method according to one embodiment includes, prior to an execution of a deterministic program, determining a pre-computed check sequence for a first plurality of values associated with the execution of the deterministic program, during the execution of the deterministic program, determining a runtime check sequence for a second plurality of values associated with the execution of the deterministic program, comparing the pre-computed check sequence to the runtime check sequence; and identifying one or more errors associated with the execution of the deterministic program, based on the comparing.
FILED	Friday, May 31, 2019
APPL NO	16/428558
ART UNIT	2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 11/14 (20130101) G06F 11/085 (20130101) G06F 11/0796 (20130101) G06F 11/1048 (20130101) Original (OR) Class G06F 11/1608 (20130101)
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10831629 — Multi-agent plan recognition

US 10831629	Riabov et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York)
ABSTRACT	Techniques for solving a multi-agent plan recognition problem are provided. In one example, a computer-implemented method comprises transforming, by a device operatively coupled to a processor, a problem model and an at least partially ordered sequence of observations into an artificial intelligence planning problem through a transform algorithm. The problem model can comprises a domain description from a plurality of agents and a durative action. Furthermore, at least one of the observations of the at least partially ordered sequence of observations can be a condition that changes over time. The computer-implemented method further comprises determining, by the device, plan information using an artificial intelligence planner on the artificial intelligence planning problem. The computer-implemented method further comprises translating, by the device, the plan information into information indicative of a solution to the artificial intelligence planning problem.
FILED	Friday, January 27, 2017
APPL NO	15/418452
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 9/4862 (20130101) G06F 11/302 (20130101) Original (OR) Class G06F 11/3006 (20130101) G06F 11/3438 (20130101) G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101)
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10831800 — Query expansion

US 10831800	Castelli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Vittorio Castelli (Croton on Hudson, New York); Radu Florian (Danbury, Connecticut); Taesun Moon (Scarsdale, New York); Avirup Sil (Ossining, New York)
ABSTRACT	A query expansion method, system, and computer program product, include establishing a context of a query to execute the query within a search index by labeling phrases of interest of the query, expanding of the phrases of interest based on a language model and a topic model, and identifying and incorporating an available historical query into the context according to a historical phrase of interest and an expansion of one or more historical phrases of interest, and retrieving and displaying one or more search results based on the query and the context of the query as a first visual mark indicating a linkage between one or more terms of the query and the one or more search results and a second visual mark indicating an alignment between the available historical query and a match to the terms of the query and the search result.
FILED	Friday, August 26, 2016
APPL NO	15/248974
ART UNIT	2162 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/3338 (20190101) Original (OR) Class G06F 16/3349 (20190101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101)
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10831889 — Secure memory implementation for secure execution of virtual machines

US 10831889	Hall et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	William E. Hall (Clinton, Connecticut); Guerney D. H. Hunt (Yorktown Heights, New York); Ronald N. Kalla (Round Rock, Texas); Jentje Leenstra (Bondorf, Germany); Paul Mackerras (Weston, Australia); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas)
ABSTRACT	A system, a method, and a computer program product for secure memory implementation for secure execution of virtual machines are provided. Data is processed in a first mode and a second mode, and commands are sent to a chip interconnect bus using real addresses, wherein the chip interconnect bus transports a number of bits for the real addresses. A memory controller is operatively coupled to a memory component. A secure memory range is specified by using range registers. If the real address is detected to be in the secure memory range to match a memory component address, a real address bit is set. If the real address is in the memory address hole, a security access violation is detected. If the real address is not in the secure address range and the real address bit is set, the security access violation is detected.
FILED	Tuesday, August 13, 2019
APPL NO	16/539537
ART UNIT	2495 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 9/45558 (20130101) G06F 12/1441 (20130101) G06F 13/364 (20130101) G06F 13/404 (20130101) G06F 21/53 (20130101) G06F 21/78 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 21/6281 (20130101) G06F 2009/45587 (20130101) G06F 2212/1052 (20130101) G06F 2221/034 (20130101)
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10832121 — Transform for a neurosynaptic core circuit

US 10832121	Appuswamy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Rathinakumar Appuswamy (San Jose, California); Myron D. Flickner (San Jose, California); Dharmendra S. Modha (San Jose, California)
ABSTRACT	Embodiments of the present invention provide a method for feature extraction comprising generating synaptic connectivity information for a neurosynaptic core circuit. The core circuit comprises one or more electronic neurons, one or more electronic axons, and an interconnect fabric including a plurality of synapse devices for interconnecting the neurons with the axons. The method further comprises initializing the interconnect fabric based on the synaptic connectivity information generated, and extracting a set of features from input received via the electronic axons. The set of features extracted comprises a set of features with reduced correlation.
FILED	Monday, April 22, 2019
APPL NO	16/391092
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Electric Digital Data Processing G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/088 (20130101) G06N 3/0635 (20130101)
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10832125 — Implementing a neural network algorithm on a neurosynaptic substrate based on metadata associated with the neural network algorithm

US 10832125	Amir et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Arnon Amir (Saratoga, California); Rathinakumar Appuswamy (San Jose, California); Pallab Datta (San Jose, California); Myron D. Flickner (San Jose, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Benjamin G. Shaw (San Francisco, California)
ABSTRACT	One embodiment of the invention provides a system for mapping a neural network onto a neurosynaptic substrate. The system comprises a metadata analysis unit for analyzing metadata information associated with one or more portions of an adjacency matrix representation of the neural network, and a mapping unit for mapping the one or more portions of the matrix representation onto the neurosynaptic substrate based on the metadata information.
FILED	Wednesday, February 28, 2018
APPL NO	15/908415
ART UNIT	2126 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/061 (20130101) Original (OR) Class G06N 3/105 (20130101)
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10832151 — Implementing stochastic networks using magnetic tunnel junctions

US 10832151	Jackson et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Bryan L. Jackson (Fremont, California); Dharmendra S. Modha (San Jose, California)
ABSTRACT	Embodiments of the invention relate to implementing a probabilistic graphical model (PGM) using magnetic tunnel junctions (MTJs). One embodiment comprises a memory array of magnetic tunnel junctions and a driver unit for programming the memory array to represent a probabilistic graphical model. The magnetic tunnel junctions are organized into multiple subsets of magnetic tunnel junctions. The driver unit selectively applies an electrical pulse to a subset of magnetic tunnel junctions to program information representing a probabilistic belief state in said subset of magnetic tunnel junctions.
FILED	Monday, August 22, 2016
APPL NO	15/243802
ART UNIT	2126 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/048 (20130101) G06N 7/005 (20130101) Original (OR) Class
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10832180 — Artificial intelligence system that employs windowed cellular automata to create plausible alternatives

US 10832180	Yeoh et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Terence Yeoh (Pasadena, California); Nehal Desai (El Segundo, California)
ABSTRACT	An artificial intelligence (AI) system is disclosed that employs windowed cellular automata to create plausible alternatives. A cellular automata-based technique may be utilized to perform pattern recognition and assess the best path available (i.e., “instant improv”). Alternative sequences (i.e., “pattern improv”) may also be used to determine alternative paths. This instant improv and pattern improv may then be used to create completely new, plausible alternative nodes. The subsequent evaluation of the sentiment further creates new, dynamic capabilities. Through the use of windowed memory learning, recall, and interpolation, new plausible structures are generated that predict dynamic systems.
FILED	Monday, October 22, 2018
APPL NO	16/166691
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 17/148 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) Original (OR) Class
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10832349 — Modeling user attitudes toward a target from social media

US 10832349	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Jilin Chen (Sunnyvale, California); Huiji Gao (Phoenix, Arizona); Jalal U. Mahmud (San Jose, California); Michelle X. Zhou (Saratoga, California)
ABSTRACT	Embodiments relate to user attitude modeling and behavior prediction for a social media network. One aspect includes collecting data relating to previously demonstrated sentiments, opinions, and actions attributed to network users toward a topic. Another aspect includes creating a model from the data, which includes factorizing the actions for behavior inference, factorizing auxiliary content from the network for opinion and sentiment inferences, and applying sentiment and opinion regularization to constrain user preferences on implicit topics to explicit sentiments and explicit opinions. Another aspect includes applying the model to a new user of the network with respect to the topic, and generating a prediction with respect to the user that includes predicting sentiment and opinion as a function of the auxiliary content and feature coefficients learned during a training process, and predicting a future action of the user as a function of the auxiliary content and latent profiles of the topic.
FILED	Monday, June 02, 2014
APPL NO	14/293094
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/02 (20130101) G06Q 50/01 (20130101) Original (OR) Class
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10832868 — Thin film capacitors

US 10832868	Zhang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Qiming Zhang (University Park, Pennsylvania); Yash Thakur (University Park, Pennsylvania); James Runt (University Park, Pennsylvania); Tian Zhang (University Park, Pennsylvania)
ABSTRACT	Dielectric capacitors including dielectric compositions with high dielectric constant, low dielectric loss, and high thermal stability are disclosed. The dielectric compositions can include a dipolar polymer having a high glass transition temperature (e.g., T_g>150° C.) in combination with either (i) another dipolar polymer having a high glass transition temperature (e.g., T_g≥150° C.) in the form of a blend, or (ii) the dipolar polymer with an inorganic interfacial agent volume content less than 2 vol % in the dielectric composition.
FILED	Friday, February 17, 2017
APPL NO	16/082977
ART UNIT	1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/38 (20130101) C08K 2003/385 (20130101) C08K 2003/2227 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 75/02 (20130101) C08L 79/08 (20130101) C08L 81/06 (20130101) C08L 2203/16 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/18 (20130101) Original (OR) Class H01G 4/20 (20130101) H01G 4/33 (20130101)
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10832885 — Electron transparent membrane for cold cathode devices

US 10832885	Akinwande et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Akintunde I. Akinwande (Newton, Massachusetts); Stephen Angelo Guerrera (Waitsfield, Vermont)
ABSTRACT	According to some aspects, a cold cathode device is provided, the device comprising a substrate, a field electron emitter disposed upon the substrate and configured to emit electrons in a first direction, and a structure encapsulating the field electron emitter, thereby creating an airtight seal around the field electron emitter, at least a portion of the structure being an atomically thin membrane positioned in the first direction with respect to the field electron emitter. According to some embodiments, at least one einzel lens may be located within the structure and configured to direct electrons emitted by the field electron emitter.
FILED	Friday, December 23, 2016
APPL NO	16/063891
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 1/52 (20130101) H01J 1/304 (20130101) H01J 29/62 (20130101) H01J 29/64 (20130101) H01J 29/86 (20130101) H01J 29/94 (20130101) H01J 37/073 (20130101) Original (OR) Class
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10833283 — Insulating tunneling contact for efficient and stable perovskite solar cells

US 10833283	Huang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Jinsong Huang (Lincoln, Nebraska); Xiaopeng Zheng (Lincoln, Nebraska); Qi Wang (Lincoln, Nebraska); Yang Bai (Lincoln, Nebraska); Qingfeng Dong (Lincoln, Nebraska)
ABSTRACT	Perovskite-based photoactive devices, such as solar cells, include an insulating tunneling layer inserted between the perovskite photoactive material and the electron collection layer to reduce charge recombination and concomitantly provide water resistant properties to the device.
FILED	Thursday, September 13, 2018
APPL NO	16/130797
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0034 (20130101) H01L 51/0046 (20130101) H01L 51/0047 (20130101) H01L 51/0091 (20130101) Original (OR) Class H01L 51/442 (20130101) H01L 51/4246 (20130101) H01L 51/4286 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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10833318 — Three-dimensional architected pyrolyzed electrodes for use in secondary batteries and methods of making three-dimensional architected electrodes

US 10833318	Greer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Julia R. Greer (San Marino, California); Andrey Vyatskikh (Irvine, California); John S. Thorne (Sunnyvale, California); Akira Kudo (San Gabriel, California); Kai Narita (Pasadena, California); Michael A. Citrin (South Pasadena, California); Xuan Zhang (Pasadena, California)
ABSTRACT	In an aspect, an electrode for an electrochemical cell comprises: a structure having a nano- or micro-architected three-dimensional geometry; said structure comprising one or more active carbon allotrope materials; wherein said structure is characterized by an average density less than or equal to 2.3 g cm⁻³and an average specific strength (strength-to-density ratio) greater than or equal to 0.004 GPa g⁻¹cm³. Also disclosed herein are methods for making an electrode for an electrochemical cell, and methods for making an electrochemical cell.
FILED	Wednesday, October 03, 2018
APPL NO	16/151186
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/32 (20130101) H01G 11/34 (20130101) H01G 11/38 (20130101) H01G 11/46 (20130101) H01G 11/84 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101)
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10833392 — Reconfigurable foldable and/or origami passive arrays

US 10833392	Zekios et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Akash Biswas (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Akash Biswas (Miami, Florida)
ABSTRACT	Passive antenna arrays and methods of using and fabricating the same are provided. A passive antenna array can include a substrate that is capable of being folded and a plurality of antenna elements disposed on the substrate. The substrate can have predefined folding lines such that the substrate can be folded into different positions. The antenna elements can be separated from each other by the folding lines in the substrate. The passive antenna array can exhibit dual band operation and can change its frequency by changing its shape.
FILED	Wednesday, August 21, 2019
APPL NO	16/546830
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/1235 (20130101) Original (OR) Class H01Q 5/30 (20150115) H01Q 21/061 (20130101) H01Q 21/0087 (20130101)
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10833404 — Scrolling reconfigurable arrays

US 10833404	Kaddour et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida)
ABSTRACT	A scrollable reflectarray antenna system and methods for reconfiguring electromagnetic (EM) characteristics of the reflectarray antenna are provided. The reconfigurable reflectarray antenna includes a flexible substrate; a plurality of reflectarray patterns disposed on a surface of the flexible substrate, each reflectarray pattern comprising a plurality of reflectarray elements; and an actuator system coupled with the flexible substrate. The actuator system is configured to scroll the flexible substrate to different operational positions such that when layout of the plurality of reflectarray patterns is changed, at least one EM characteristic of the reflectarray antenna is reconfigured. In a predetermined operational position, an aperture of the reflectarray is formed by two reflectarray patterns that are optimized to direct an illuminating beam in a new direction.
FILED	Friday, May 01, 2020
APPL NO	16/864335
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/04 (20130101) Original (OR) Class H01Q 3/46 (20130101) H01Q 21/065 (20130101)
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10833405 — Method of tracking steerable antennas on platforms to form an RF communication link

US 10833405	Brown et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Kenneth W. Brown (Yucaipa, California); Alan Rattray (Georgetown, Texas); Travis B. Feenstra (Calimesa, California); Samuel De La Torre (La Habra, California); Johan A. Kullstam (Marlborough, Massachusetts); Arlin L. Pierce (San Antonio, Texas)
ABSTRACT	Steerable antenna on platforms, fixed or mobile, are tracked to form an RF communication link by setting the width of the main lobe of the antenna beam pattern to be greater than the initial pointing uncertainty region and then concurrently scanning and progressively reducing the widths of the main lobes as the pointing uncertainty region is reduced to first acquire and then track the opposing antenna. The width of the main lobe is reduced such that the width of the main lobe is approximately fixed for each block. The antennas at opposite ends of the communication link may be scanned with scan patterns that are orthogonal to each other such that the demodulation of the received signal levels to signal direction of arrival at each platform is solely a function of the scan pattern of the receive antenna.
FILED	Thursday, July 21, 2016
APPL NO	15/760429
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/10 (20130101) H01Q 3/18 (20130101) H01Q 3/20 (20130101) Original (OR) Class H01Q 19/10 (20130101) H01Q 19/19 (20130101) Transmission H04B 7/0617 (20130101)
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10833423 — Dual polarized notch antenna having low profile stripline feed

US 10833423	Brigham
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Glenn A. Brigham (Chelmsford, Massachusetts)
ABSTRACT	In this novel geometry, the 3D radiator unit cell has been designed with flat sided unit cells. Each 3D radiator unit cell incorporates a curf border of sacrificial material. This border permits independent sub-array size and shape. It also allows a gap between sub-arrays while retaining contiguous unit cell spacing giving flexibility to array size, shape and line replaceable unit capabilities.
FILED	Thursday, February 28, 2019
APPL NO	16/288986
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 13/18 (20130101) H01Q 21/22 (20130101) Original (OR) Class H01Q 21/0075 (20130101)
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10833557 — Dual purpose no voltage winding design for bearingless AC homopolar and consequent pole motors and an AC homopolar flywheel energy storage system

US 10833557	Severson
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S)	Eric Severson (Middleton, Wisconsin)
ABSTRACT	A motor includes a rotor used in conjunction with a stator to produce a magnetic field in the air gap having p pole pairs, wherein a single cross section of the rotor taken orthogonal to an axis of rotation comprises iron having a structure forming p teeth. The stator has at least one stator winding configured to form p pole pairs to produce a first magnetic field to rotate the rotor about the axis of rotation and configured to produce a second magnetic field of either one pole pair or p±1 pole pairs to create forces radial to the axis of rotation. The at least one stator winding has two sets of terminals, a first set of terminals for carrying current that produces the first magnetic field in the air gap having p pole pairs to rotate the rotor about the axis of rotation and a second set of terminals for carrying current that produces the second magnetic field in the air gap having either one pole pair or p±1 pole pairs to create the forces radial to the axis of rotation. The second set of terminals experience no motional-electromotive force when the rotor is centered on the axis of rotation.
FILED	Friday, August 04, 2017
APPL NO	15/669594
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/0497 (20130101) F16C 2380/28 (20130101) Dynamo-electric Machines H02K 3/28 (20130101) H02K 7/09 (20130101) H02K 7/025 (20130101) Original (OR) Class H02K 11/33 (20160101) H02K 19/20 (20130101) H02K 19/103 (20130101) H02K 31/02 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 25/18 (20130101) H02P 25/22 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/16 (20130101)
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10833658 — Apparatuses and methods using current-starved ring oscillator biased by floating gate transistors with a variety of applications including as a power-free radiation detector or silicon age determination or odometer system

US 10833658	Kay et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew J Kay (Jasper, Indiana); Adam Duncan (Bloomington, Indiana); Matthew Gadlage (Bloomington, Indiana); Austin H Roach (Bloomington, Indiana); Glenn Berger (Bloomington, Indiana)
ABSTRACT	Apparatuses and methods using current-starved ring oscillator biased by floating gate transistors with a variety of applications including as a power-free radiation detector or silicon age determination or odometer system.
FILED	Friday, December 28, 2018
APPL NO	16/235228
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 1/245 (20130101) G01T 1/246 (20130101) Pulse Technique H03K 3/0315 (20130101) Original (OR) Class
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10833725 — Methods, systems, and articles of manufacture for joint decoding of packets in wireless networks using chirp spread-spectrum modulation

US 10833725	Dongare et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Adwait Dongare (Pittsburgh, Pennsylvania); Artur Balanuta (Pittsburgh, Pennsylvania); Akshay Gadre (Pittsburgh, Pennsylvania); Robert Iannucci (Palo Alto, California); Swarun Kumar (Pittsburgh, Pennsylvania); Anh Luong (Pittsburgh, Pennsylvania); Revathy Narayanan (Chennai, India); Anthony Rowe (Pittsburgh, North Carolina)
ABSTRACT	A method of providing wireless communications in a wireless network can include wirelessly receiving a chirp spread-spectrum modulated signal at a first gateway device, the chirp spread-spectrum modulated signal being transmitted by a remote client device. The chirp spread-spectrum modulated signal can be demodulated at the first gateway device to provide demodulated data at the first gateway device. The demodulated data can be processed to provide an indication that a decode of a packet including the demodulated data failed. Time adjacent chirps included in the demodulated data can be combined to provide combined data at the first gateway device. A message can be transmitted from the first gateway device to a remote server responsive to an amplitude of the combined data exceeding a threshold value and the indication that the decode of the packet including the demodulated data failed.
FILED	Tuesday, June 02, 2020
APPL NO	16/890102
ART UNIT	2632 — Digital Communications
CURRENT CPC	Demodulation or Transference of Modulation From One Carrier to Another H03D 3/009 (20130101) Transmission H04B 1/12 (20130101) H04B 1/7102 (20130101) Original (OR) Class H04B 2001/6912 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/364 (20130101) H04L 27/3818 (20130101)
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10834842 — Rack-mountable assembly with spring-hinged mounting bracket(s)

US 10834842	Elsasser et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Ryan Elsasser (Poughkeepsie, New York); William Risk (San Jose, California); Camillo Sassano (Durham, North Carolina); Matthew Butterbaugh (Rochester, Minnesota); Michael Good (Fountain, Minnesota); Kevin L. Schultz (Raleigh, North Carolina)
ABSTRACT	Rack-mountable assemblies are provided which include a structure to be mounted to a frame of an electronics rack, and a spring-hinged mounting bracket associated with and extending from a side of the structure to facilitate mounting the structure to the frame of the electronics rack. The spring-hinged mounting bracket facilitates insertion of the structure into the frame by pivoting inward towards the side of the structure upon the spring-hinged mounting bracket encountering an obstruction as the rack-mountable assembly is positioned within the frame for mounting to the frame.
FILED	Friday, June 21, 2019
APPL NO	16/448125
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/16 (20130101) H05K 7/183 (20130101) H05K 7/1489 (20130101) Original (OR) Class
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10834848 — Cold plate device for a two-phase cooling system

US 10834848	Chainer et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Stamford, Connecticut); Fanghao Yang (Somerset, New Jersey)
ABSTRACT	Techniques that facilitate two-phase liquid cooling of an electronic device are provided. In one example, an apparatus, such as a cold plate device, comprises a first stackable layer and a second stackable layer. The first stackable layer comprises a first channel formed within the first stackable layer. The first channel comprises a first channel width and the first channel receives a coolant fluid via an inlet port of the apparatus. The second stackable layer comprises a second channel that provides a path for the coolant fluid to flow between the first channel and an outlet port of the apparatus. A width of the second channel increases along a flow direction of the coolant fluid that flows between the inlet port and the outlet port.
FILED	Tuesday, May 07, 2019
APPL NO	16/405214
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/12 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20254 (20130101) Original (OR) Class H05K 7/20272 (20130101)
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National Science Foundation (NSF)

10827911 — Optical imaging system employing vortex fiber for multiple-mode illumination

US 10827911	Ramachandran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts); OFS FITEL, LLC (Norcross, Georgia)
INVENTOR(S)	Siddharth Ramachandran (Boston, Massachusetts); Lu Yan (Sunnyvale, California); Poul Kristensen (Valby, Denmark)
ABSTRACT	A vortex optical fiber for use in an illumination subsystem of an optical imaging system (e.g., a stimulated emission depletion (STED) microscopy system) includes an elongated optically transmissive medium having a set of regions including a core region, a trench region surrounding the core region, a ring region surrounding the trench region, and a cladding region, the set of regions having a doping profile providing a Δn_efffor vector modes in an LP₁₁mode group of greater than 1×10⁻⁴in the visible spectral range so as to simultaneously guide stable Gaussian and orbital angular momentum (OAM) carrying modes at corresponding visible wavelengths.
FILED	Monday, June 05, 2017
APPL NO	16/306026
ART UNIT	2874 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0017 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/0008 (20130101) G02B 6/0286 (20130101) G02B 6/02071 (20130101) G02B 6/02195 (20130101) G02B 6/02366 (20130101) G02B 6/02395 (20130101) G02B 6/03644 (20130101) G02B 21/0028 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) G02B 27/58 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/094 (20130101)
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10828373 — Bioorthogonal compositions

US 10828373	Mejia Oneto et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI)
APPLICANT(S)	TAMBO, INC. (San Francisco, California)
ASSIGNEE(S)	Tambo, Inc. (San Francisco, California)
INVENTOR(S)	Jose Mejia Oneto (San Francisco, California); Robert Galemmo, Jr. (Hong Kong, China PRC)
ABSTRACT	The present disclosure provides bioorthogonal compositions for delivering agents in a subject. The disclosure also provides methods of producing the compositions, as well as methods of using the same.
FILED	Monday, September 12, 2016
APPL NO	15/759056
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 31/35 (20130101) A61K 31/337 (20130101) A61K 31/453 (20130101) A61K 38/08 (20130101) A61K 47/18 (20130101) A61K 47/61 (20170801) Original (OR) Class A61K 47/555 (20170801) A61K 47/6903 (20170801) A61K 47/6939 (20170801) A61K 49/0032 (20130101) A61K 49/0054 (20130101) A61K 49/0073 (20130101) A61K 51/0495 (20130101) A61K 51/1213 (20130101) A61K 51/1244 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101)
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10828398 — Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use

US 10828398	Jiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Shaoyi Jiang (Redmond, Washington); Tao Bai (Seattle, Washington); Harihara Subramanian Sundaram (Seattle, Washington); Andrew William Sinclair (Seattle, Washington); Jean-René Ella-Menye (Seattle, Washington); Priyesh Jain (Seattle, Washington)
ABSTRACT	Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
FILED	Monday, April 29, 2019
APPL NO	16/398002
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 47/58 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/24 (20130101) A61L 15/42 (20130101) A61L 24/0031 (20130101) A61L 24/046 (20130101) A61L 27/16 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/021 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 2533/30 (20130101) C12N 2539/00 (20130101)
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10828664 — Device and method for making shear-aligned, solvent-cast films

US 10828664	Shelton et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) NIST Center for Neutron Research (NCNR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Cameron Shelton (Bear, Delaware); Thomas H. Epps, III (Bear, Delaware)
ASSIGNEE(S)	UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S)	Cameron Shelton (Bear, Delaware); Thomas H. Epps, III (Bear, Delaware)
ABSTRACT	A coating head includes a coating device and at least a first flexible blade that is capable of being shaped into contact with a solvent-containing film on a substrate upon pressing the first flexible blade against the film, thereby providing contact between the blade and the film over a contact distance when the coating head is drawn over the substrate. The coating device and the blade are separated by a spacing distance such that partial loss of solvent occurs from a starting film formed on the substrate by the coating device as the coating head is drawn over the substrate, the partial solvent loss forming the solvent-containing film. A method of producing a film having a hierarchical structure includes drawing a coating head across a substrate to form on the substrate via the coating device a starting film including a solvent and a material for forming the hierarchical structure.
FILED	Thursday, December 08, 2016
APPL NO	15/776289
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Apparatus for Applying Fluent Materials to Surfaces, in General B05C 11/045 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/42 (20130101) Original (OR) Class B05D 2252/02 (20130101) Optical Elements, Systems, or Apparatus G02B 5/30 (20130101)
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10829381 — Borophenes, boron layer allotropes and methods of preparation

US 10829381	Hersam et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois)
ABSTRACT	A method of preparing an atomically-dimensioned elemental boron allotrope includes providing a substrate at a temperature greater than about 200° C.; generating elemental boron vapor from a solid elemental boron source; and contacting said substrate with said boron vapor for at least one of a rate and at a pressure sufficient to deposit on said substrate a boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension, said method under negative pressure.
FILED	Friday, May 29, 2020
APPL NO	16/886936
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101)
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10829445 — N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors

US 10829445	Toscano et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Cardioxyl Pharmaceuticals, Inc. (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	Cardioxyl Pharmaceuticals, Inc. (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	John P. Toscano (Glen Arm, Maryland); Frederick Arthur Brookfield (Abingdon, United Kingdom); Andrew D. Cohen (Mamaroneck, New York); Stephen Martin Courtney (Abingdon, United Kingdom); Lisa Marie Frost (Abingdon, United Kingdom); Vincent Jacob Kalish (Annapolis, Maryland)
ABSTRACT	The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release HNO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
FILED	Friday, November 15, 2019
APPL NO	16/685534
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 311/48 (20130101) Original (OR) Class C07C 317/14 (20130101) C07C 323/67 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 231/18 (20130101) C07D 261/10 (20130101) C07D 263/58 (20130101) C07D 285/125 (20130101) C07D 295/096 (20130101) C07D 307/82 (20130101) C07D 309/12 (20130101) C07D 317/14 (20130101) C07D 333/34 (20130101) C07D 333/62 (20130101) Technologies for Adaptation to Climate Change Y02A 50/414 (20180101)
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10829571 — Polymer-encased nanodiscs with improved buffer compatibility

US 10829571	Altenberg et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S)	Texas Tech University System (Lubbock, Texas)
INVENTOR(S)	Guillermo A. Altenberg (Lubbock, Texas); Hongjun Liang (Lubbock, Texas)
ABSTRACT	The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.
FILED	Thursday, August 30, 2018
APPL NO	16/117073
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 8/12 (20130101) C08F 8/12 (20130101) C08F 8/40 (20130101) Original (OR) Class C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 212/08 (20130101) C08F 212/08 (20130101) C08F 222/06 (20130101) C08F 222/06 (20130101) C08F 222/08 (20130101) C08F 222/08 (20130101) C08F 2438/03 (20130101) Compositions of Macromolecular Compounds C08L 33/00 (20130101) C08L 33/26 (20130101) C08L 35/06 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/96 (20130101) C12N 11/04 (20130101) C12N 11/08 (20130101) Enzymes C12Y 306/01003 (20130101)
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10829612 — Methods of recycling and reshaping thermosetting polymers and composites thereof

US 10829612	Qi et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Hang Qi (Atlanta, Georgia); Kai Yu (Atlanta, Georgia); Qian Shi (Atlanta, Georgia)
ABSTRACT	Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
FILED	Monday, July 03, 2017
APPL NO	16/314549
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/16 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/195 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) C08J 5/121 (20130101) C08J 11/24 (20130101) Original (OR) Class C08J 2363/00 (20130101) C08J 2367/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/103 (20130101) C08K 7/14 (20130101)
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10829727 — Engineered platform to generate 3D cardiac tissues

US 10829727	Chen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S)	Christopher S. Chen (Newton, Massachusetts); Rebeccah Luu (Cambridge, Massachusetts); Anant Chopra (Waltham, Massachusetts)
ABSTRACT	Described herein are a system, device, methods and compositions related to generating 3-dimensional cardiac tissues. Also described herein are a system, device, and methods of maturing 3-dimensional cardiac tissues and maintaining their viability in culture.
FILED	Thursday, April 11, 2019
APPL NO	16/381866
ART UNIT	1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/12 (20130101) C12M 25/14 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0606 (20130101) C12N 5/0657 (20130101) C12N 5/0696 (20130101) C12N 2533/90 (20130101)
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10829729 — Cellular poration using laser radiation

US 10829729	Mazur et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	President and Fellows Of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Eric Mazur (Concord, Massachusetts); Nabiha Saklayen (Cambridge, Massachusetts); Marinna Madrid (Cambridge, Massachusetts); Marinus Huber (Munich, Germany); Valeria Nuzzo (Paris, France)
ABSTRACT	In one aspect, a method of cell processing is disclosed, which includes disposing a plurality of cells on a substrate across which a plurality of projections are distributed and an electrically conductive layer at least partially coating said projections, exposing the cells to a cargo to be internalized by the cells, irradiating the substrate surface (and in particular the projections) with continuous wave or pulsed laser radiation. For example, one or more laser pulses having a pulse width in a range of about 1 ns to about 1000 ns can be applied so as to facilitate uptake of the cargo by at least a portion of the cells (e.g., the cells positioned in the vicinity of the projections (e.g., within hundreds of nanometer (such as less than 100 nm) of the projections)). In some embodiments, the laser pulses have a pulse width in a range of about 10 ns to about 500 ns, e.g., in a range of about 5 ns to about 50 ns.
FILED	Thursday, January 17, 2019
APPL NO	16/250714
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101)
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10829779 — Use of elongator genes to improve plant disease resistance

US 10829779	Mou et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S)	Zhonglin Mou (Gainesville, Florida); Yezhang Ding (La Jolla, California); Xudong Zhang (Gainesville, Florida); Kevin M. Folta (Gainesville, Florida)
ABSTRACT	The invention provides methods and compositions for producing plants displaying enhanced disease resistance by transgenic over-expression of Elongator Complex subunit ELP3 or ELP4 genes. Methods and compositions for production of plants with altered growth habit (e.g. runner development) are also provided.
FILED	Tuesday, July 12, 2016
APPL NO	15/743230
ART UNIT	1662 — Plants
CURRENT CPC	Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8222 (20130101) C12N 15/8281 (20130101) Original (OR) Class C12N 15/8282 (20130101)
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10829792 — Biocatalytic synthesis of strained carbocycles

US 10829792	Chen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Kai Chen (Pasadena, California); Xiongyi Huang (Pasadena, California); S. B. Jennifer Kan (Pasadena, California)
ABSTRACT	Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods include combining an alkyne and a carbene precursor in the presence of a heme protein, e.g., a cytochrome P450, under conditions sufficient to form the strained carbocycle. Reaction mixtures for producing strained carbocycles are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming cyclopropenes, bicyclobutanes, and related products.
FILED	Wednesday, March 21, 2018
APPL NO	15/927971
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0042 (20130101) C12N 9/0071 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) Original (OR) Class Enzymes C12Y 106/02004 (20130101)
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10829795 — Method for rapid in vitro synthesis of glycoproteins via recombinant production of N-glycosylated proteins in prokaryotic cell lysates

US 10829795	Jewett et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York)
INVENTOR(S)	Michael Christopher Jewett (Evanston, Illinois); Jessica Carol Stark (Evanston, Illinois); Matthew P. DeLisa (Ithaca, New York); Thapakorn Jaroentomeechai (Ithaca, New York)
ABSTRACT	Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated proteins. The glycosylated proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. The glycosylated proteins may be synthesized in cell-free glycoprotein synthesis (CFGpS) systems using prokaryote cell lysates that are enriched in components for glycoprotein synthesis such as oligosaccharyltransferases (OSTs) and lipid-linked oligosaccharides (LLOs) including OSTs and LLOs associated with synthesis of bacterial O antigens.
FILED	Friday, July 14, 2017
APPL NO	15/650127
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) A61K 38/16 (20130101) A61K 39/0208 (20130101) A61K 39/0258 (20130101) A61K 2039/6037 (20130101) A61K 2039/6068 (20130101) Peptides C07K 7/06 (20130101) C07K 9/00 (20130101) C07K 14/00 (20130101) C07K 14/47 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/10 (20130101) C12N 9/1081 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/00 (20130101) C12P 21/00 (20130101) C12P 21/02 (20130101) C12P 21/005 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/00 (20130101) C12R 1/19 (20130101) C12R 1/145 (20130101) Enzymes C12Y 204/99019 (20150701) Technologies for Adaptation to Climate Change Y02A 50/47 (20180101) Y02A 50/404 (20180101) Y02A 50/473 (20180101)
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10829804 — Method for identification and enumeration of nucleic acid sequences, expression, splice variant, translocation, copy, or DNA methylation changes using combined nuclease, ligase, polymerase, terminal transferase, and sequencing reactions

US 10829804	Barany et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Francis Barany (New York, New York); John William Efcavitch (San Carlos, California); Steven A. Soper (Baton Rouge, Louisiana); Sunggook Park (Baton Rouge, Louisiana)
ABSTRACT	The present invention is directed methods for identifying, in a sample, one or more target nucleotide sequences differing from other nucleotide sequences in the sample by one or more nucleotides, one or more copy numbers, one or more transcript sequences, and/or one or more methylated residues, using ligation detection reactions, polymerase mediated extension reactions, and/or cleavage reactions. The present invention is also directed to methods for identifying, in a sample, one or more nucleotides in a target nucleotide sequence.
FILED	Wednesday, March 23, 2016
APPL NO	15/560805
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2521/301 (20130101) C12Q 2521/331 (20130101) C12Q 2531/125 (20130101) C12Q 2535/125 (20130101) C12Q 2561/109 (20130101) C12Q 2561/125 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101)
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10829812 — Amplification of oligonucleotides containing non-standard nucleotides

US 10829812	Benner et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Steven A Benner (Gainesville, Florida); Roberto Laos (Gainesville, Florida); Nicole A Leal (Gainesville, Florida); Zunyi Yang (Gainesville, Florida); Myong Jung Kim (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S)	Steven A Benner (Gainesville, Florida); Roberto Laos (Gainesville, Florida); Nicole A Leal (Gainesville, Florida); Zunyi Yang (Gainesville, Florida); Myong Jung Kim (Gainesville, Florida)
ABSTRACT	This invention relates to processes that amplify oligonucleotide analogs that incorporate non-standard nucleobase analogs from an artificially expanded genetic information system. These pair in DNA duplexes via patterns of hydrogen bonds that differ from patterns that join the thymine-adenine and guanine-cytosine nucleobase pairs.
FILED	Tuesday, December 11, 2018
APPL NO	16/216266
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) C12Q 2525/117 (20130101)
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10830639 — Devices, methods, and systems relating to super resolution imaging

US 10830639	Urban et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Eye Institute (NEI) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ben Urban (Evanston, Illinois); Hao F. Zhang (Deerfield, Illinois); Cheng Sun (Wilmette, Illinois); Biqin Dong (Evanston, Illinois)
ABSTRACT	Certain examples disclose systems and methods for imaging a target. An example method includes: a) activating a subset of light-emitting molecules in a wide field area of a target using an excitation light; b) capturing one or more images of the light emitted from the subset of the molecules illuminated with the excitation light; c) localizing one or more activated light emitting molecules using one or more single molecule microscopic methods to obtain localization information; d) simultaneously capturing spectral information for the same localized activated light emitting molecules using one or more spectroscopic methods; e) resolving one or more non-diffraction limited images of the area of the target using a combination of the localization and spectral information for the localized activated light emitting molecules; and f) displaying the one or more non-diffraction limited images.
FILED	Friday, September 25, 2015
APPL NO	15/514084
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/84 (20130101) G01N 21/6458 (20130101) G01N 33/483 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0064 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101)
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10830692 — System and method to measure dissolved gases in liquid

US 10830692	Wang et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) National Science Foundation (NSF) Directorate of Geosciences (GEO) Division of Ocean Sciences (OCE)
APPLICANT(S)	Woods Hole Oceanographic Institution (Woods Hole, Massachusetts)
ASSIGNEE(S)	WOODS HOLE OCEANOGRAPHIC INSTITUTION (Woods Hole, Massachusetts)
INVENTOR(S)	Zhaohui ‘Aleck’ Wang (N. Falmouth, Massachusetts); Frederick N. Sonnichsen (Woods Hole, Massachusetts)
ABSTRACT	A high-resolution in situ sensing system and method for providing continuous measurements of at least one dissolved analyte including a sample processing cell having at least a first conduit defining a first passage with at least one selectively-permeable wall capable of passing a portion of the sample liquid into a processing, fluid. The at least one selectively-permeable wall substantially resists flow of another portion of the sample liquid therethrough. Processing fluid is directed through the first conduit while moving the sample liquid and the reagent fluid relative to each other in one of a stationary, concurrent or a countercurrent flow relationship to achieve either partial or full equilibration between the sample liquid and processing fluid to generate at least partially equilibrated reagent fluid and a processed sample in a substantially continuous manner.
FILED	Saturday, September 01, 2018
APPL NO	16/120248
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 15/06 (20130101) G01N 21/05 (20130101) G01N 21/80 (20130101) G01N 21/314 (20130101) Original (OR) Class G01N 21/783 (20130101) G01N 31/221 (20130101) G01N 33/18 (20130101) G01N 33/1886 (20130101) G01N 33/1893 (20130101) G01N 2201/0212 (20130101) G01N 2201/0216 (20130101) G01N 2201/0218 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/235 (20150115) Y10T 436/255 (20150115)
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10830757 — Universal molecular processor for precision medicine

US 10830757	Soper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Steven A. Soper (Baton Rouge, Louisiana); Francis Barany (New York, New York); Sunggook Park (Baton Rouge, Louisiana); Michael Murphy (Baton Rouge, Louisiana); Collin J. McKinney (Durham, North Carolina); John William Efcavitch (San Carlos, California); Mateusz Hupert (Chapel Hill, North Carolina)
ABSTRACT	The present invention is directed to methods comprising a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The nanotubes have a passage extending between an input end proximate to the bioreactor chamber and an output end distal to the bioreactor chamber, and comprises one or more nanopores within the passage with each nanopore having a reduced diameter relative to the passage.
FILED	Wednesday, July 17, 2019
APPL NO	16/513947
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0645 (20130101) B01L 2300/0861 (20130101) B01L 2300/0896 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/40 (20130101) C12M 23/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2561/125 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class
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10830800 — Subcircuit physical level power monitoring technology for real-time hardware systems and simulators

US 10830800	Cho et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	University of Southern California (Los Angeles, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Young H. Cho (Chatsworth, California); Siddharth S. Bhargav (Los Angeles, California)
ABSTRACT	In at least one aspect, a system is configured to use a mapping to determine per-component dynamic power consumed by components in a SoC during execution of instructions, the mapping translating consumed power per one or more instructions into consumed power per component based on a set of determined components (an adjusted set of proposed components) and derived weights, the set of proposed components having been generated to represent the components of the SoC and including a respective proposed component corresponding to each instruction, and the set of proposed components having been adjusted based on the derived weights being produced for the set of proposed components by at least combining two or more proposed components associated with two or more of the derived weights that converged to a shared value, and perform power and temperature management for the SoC in accordance with the determined per-component dynamic power consumption.
FILED	Friday, August 09, 2019
APPL NO	16/537433
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 21/133 (20130101) Original (OR) Class
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10831014 — Systems and methods for three dimensional imaging

US 10831014	Hillman
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Elizabeth M. C. Hillman (New York, New York)
ABSTRACT	Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed.
FILED	Monday, July 23, 2018
APPL NO	16/042700
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0052 (20130101) G02B 21/361 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 23/04 (20130101)
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10831232 — Computer architecture allowing recycling of instruction slack time

US 10831232	Ravi et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Gokul Subramanian Ravi (Madison, Wisconsin); Mikko H. Lipasti (Lake Mills, Wisconsin)
ABSTRACT	A computer architecture suitable for out-of-order processors manages the problem of timing slack, in which an instruction completes before its clock cycle, by recycling that slack to allow the next succeeding instruction allowing that instruction to begin execution earlier. This recycling mechanism is enabled through the use of a transparent gating between execution units which allows data transfer before clock cycle boundaries and, in some cases, by aggressively issuing children instructions contemporaneously with their parent instruction after a grandparent instruction is issued.
FILED	Friday, February 15, 2019
APPL NO	16/276744
ART UNIT	2186 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 1/10 (20130101) Original (OR) Class G06F 9/3855 (20130101)
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10831332 — User interface element for building interior previewing and navigation

US 10831332	Ullrich et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Oliver Ullrich (Miami, Florida); Naphtali Rishe (Miami Beach, Florida); Victor Potapenko (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Oliver Ullrich (Miami, Florida); Naphtali Rishe (Miami Beach, Florida); Victor Potapenko (Miami, Florida)
ABSTRACT	Methods of communicating, displaying, and storing information relating to structures, as well as apparatuses for executing such methods, are provided. The methods can be executed on touchscreen electronic devices and may be particularly useful for shopping center, cruise ship, museum, and construction applications. The methods and apparatuses allow for, for example, reviewing a building's interior, finding information on areas within a building, and navigating from a current location to a destination. A method can include defining a structure using elements, wherein the elements are three dimensional shapes, and manipulating the elements or the structure on a user interface. A user is therefore able to obtain important information about the structure clearly and effortlessly.
FILED	Thursday, February 23, 2017
APPL NO	15/440524
ART UNIT	2176 — Graphical User Interface and Document Processing
CURRENT CPC	Electric Digital Data Processing G06F 3/04815 (20130101) Original (OR) Class G06F 3/04845 (20130101) G06F 3/04883 (20130101) G06F 30/13 (20200101) G06F 2203/04808 (20130101)
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10831894 — Decentralized root-of-trust framework for heterogeneous networks

US 10831894	Kornegay et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Morgan State University (Baltimore, Maryland)
ASSIGNEE(S)	Morgan State University (Baltimore, Maryland)
INVENTOR(S)	Kevin Tyrone Kornegay (Towson, Maryland); Willie Lee Thompson, II (Perry Hall, Maryland)
ABSTRACT	Systems and methods are disclosed for providing a trusted computing environment that provides data security in commodity computing systems. Such systems and methods deploy a flexible architecture comprised of distributed trusted platform modules (TPMs) configured to establish a root-of-trust within a heterogeneous network environment comprised of non-TPM enabled IoT devices and legacy computing devices. A data traffic module is positioned between a local area network and one or more non-TPM enabled IoT devices and legacy computing devices, and is configured to control and monitor data communication among such IoT devices and legacy computing devices, and from such IoT devices and legacy computing devices to external computers. The data traffic module supports attestation of the IoT devices and legacy computing devices, supports secure boot operations of the IoT devices and legacy computing devices, and provides tamper resistance to such IoT devices and legacy computing devices.
FILED	Tuesday, January 09, 2018
APPL NO	15/865661
ART UNIT	2497 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/44 (20130101) G06F 21/57 (20130101) Original (OR) Class G06F 21/85 (20130101) G06F 21/6218 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0844 (20130101) H04L 9/0897 (20130101) H04L 9/3234 (20130101) H04L 2209/805 (20130101) Wireless Communication Networks H04W 12/08 (20130101) H04W 12/00512 (20190101) H04W 12/1208 (20190101)
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10832091 — Machine learning to process Monte Carlo rendered images

US 10832091	Sen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Pradeep Sen (Goleta, California); Steve Bako (Santa Barbara, California); Nima Khademi Kalantari (La Jolla, California)
ABSTRACT	A method of rendering an image includes Monte Carlo rendering a scene to produce a noisy image. The noisy image is processed to render an output image. The processing applies a machine learning model that utilizes colors and/or features from the rendering system for denoising the noisy image and/or to for adaptively placing samples during rendering.
FILED	Thursday, December 13, 2018
APPL NO	16/219340
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 7/005 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101)
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10832711 — Beta tungsten thin films with giant spin Hall effect for use in compositions and structures with perpendicular magnetic anisotropy

US 10832711	Xiao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	BROWN UNIVERSITY (Providence, Rhode Island)
ASSIGNEE(S)	BROWN UNIVERSITY (Providence, Rhode Island)
INVENTOR(S)	Gang Xiao (Barrington, Rhode Island); Qiang Hao (Sugar Land, Texas)
ABSTRACT	Methods, devices, and compositions for use with spintronic devices such as magnetic random access memory (MRAM) and spin-logic devices are provided. Methods include manipulating magnetization states in spintronic devices and making a structure using spin transfer torque to induce magnetization reversal. A device described herein manipulates magnetization states in spintronic devices and includes a non-magnetic metal to generate spin current based on the giant spin Hall effect, a ferromagnetic thin film with perpendicular magnetic anisotropy, an oxide thin film, and an integrated magnetic sensor. The device does not require an insertion layer between a non-magnetic metal with giant spin Hall effect and a ferromagnetic thin film to achieve perpendicular magnetic anisotropy.
FILED	Monday, December 17, 2018
APPL NO	16/221901
ART UNIT	2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/37 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/30 (20130101) H01F 10/329 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/10 (20130101) H01L 43/12 (20130101) H01L 43/14 (20130101) Pulse Technique H03K 19/18 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49032 (20150115)
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10833283 — Insulating tunneling contact for efficient and stable perovskite solar cells

US 10833283	Huang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Jinsong Huang (Lincoln, Nebraska); Xiaopeng Zheng (Lincoln, Nebraska); Qi Wang (Lincoln, Nebraska); Yang Bai (Lincoln, Nebraska); Qingfeng Dong (Lincoln, Nebraska)
ABSTRACT	Perovskite-based photoactive devices, such as solar cells, include an insulating tunneling layer inserted between the perovskite photoactive material and the electron collection layer to reduce charge recombination and concomitantly provide water resistant properties to the device.
FILED	Thursday, September 13, 2018
APPL NO	16/130797
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0034 (20130101) H01L 51/0046 (20130101) H01L 51/0047 (20130101) H01L 51/0091 (20130101) Original (OR) Class H01L 51/442 (20130101) H01L 51/4246 (20130101) H01L 51/4286 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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10833330 — Sulfur composites and polymeric materials from elemental sulfur

US 10833330	Pyun
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Dong-Chul Pyun (Tucson, Arizona)
ABSTRACT	Sulfur composites and polymeric materials having a high sulfur content and prepared from elemental sulfur as the primary chemical feedstock. The sulfur copolymers are prepared by the polymerization of elemental sulfur with one or more monomers of amines, thiols, sulfides, alkynylly unsaturated monomers, nitrones, aldehydes, ketones, thiiranes, ethylenically unsaturated monomers, or epoxides. The sulfur copolymers may be further dispersed with metal or ceramic composites or copolymerized with elemental carbon, photoactive organic chromophores, or reactive and solubilising/biocompatible moieties. The sulfur composites and polymeric materials feature the ability self-healing through thermal reformation. Applications utilizing the sulfur composites and polymeric materials may include electrochemical cells, optics, H₂S donors and antimicrobial materials.
FILED	Thursday, October 06, 2016
APPL NO	15/287118
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/6303 (20130101) C04B 2235/9653 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 4/608 (20130101) Original (OR) Class H01M 4/664 (20130101) H01M 4/5815 (20130101)
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10833353 — Stretchable and multifunctional batteries

US 10833353	Ardebili et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Haleh Ardebili (Sugarland, Texas); Taylor Dizon (Houston, Texas); Mejdi Kammoun (Humble, Texas)
ABSTRACT	A stretchable battery comprising at least one electrochemical cell further comprising a first electrode having a first active material coupled with a first current collector, a second electrode having a second active material coupled with a second current collector, an electrolytic separator configured between the first and second electrodes, and at least one stretchable substrate coupled with the formation of at least one electrochemical cell, wherein the stretchable substrate encapsulates the formation and is capable of reversible stretching.
FILED	Friday, March 27, 2015
APPL NO	14/671812
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/026 (20130101) H01M 2/0275 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/661 (20130101) H01M 4/663 (20130101) H01M 10/0436 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0565 (20130101) H01M 10/0585 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4911 (20150115)
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10833360 — Protective anode coatings for high energy batteries

US 10833360	Hegde et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Vinay Ishwar Hegde (Chicago, Illinois); David H. Snydacker (Evanston, Illinois); Christopher M. Wolverton (Evanston, Illinois)
ABSTRACT	Materials for coating a metal anode in a high energy battery, anodes coated with the materials, and batteries incorporating the coated anodes are provided. Also provided are batteries that utilize the materials as electrolytes. The coatings, which are composed of binary, ternary, and higher order metal and/or metalloid oxides, nitrides, fluorides, chlorides, bromides, sulfides, and carbides limit the reactions between the electrolyte and the metal anode in a battery, thereby improving the performance of the battery, relative to a battery that employs a bare anode.
FILED	Wednesday, March 08, 2017
APPL NO	16/081533
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101)
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10833694 — Circuits and methods for time-delay to digital converters

US 10833694	De Godoy Peixoto et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Daniel De Godoy Peixoto (Austin, Texas); Xiaofan Jiang (New York, New York); Peter Kinget (Summit, New Jersey)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Daniel De Godoy Peixoto (Austin, Texas); Xiaofan Jiang (New York, New York); Peter Kinget (Summit, New Jersey)
ABSTRACT	In accordance with some embodiments, polarity-coincidence, adaptive time-delay estimation (PCC-ATDE), mixed-signal techniques are provided. In some embodiments, these techniques use 1-bit quantized signals and negative-feedback architectures to directly determine a time-delay between signals at analog inputs and convert the time-delay to a digital number.
FILED	Monday, April 08, 2019
APPL NO	16/378550
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Time-interval Measuring G04F 10/06 (20130101) Pulse Technique H03K 5/135 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/085 (20130101) Coding; Decoding; Code Conversion in General H03M 1/20 (20130101) H03M 1/1215 (20130101) Original (OR) Class
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10833725 — Methods, systems, and articles of manufacture for joint decoding of packets in wireless networks using chirp spread-spectrum modulation

US 10833725	Dongare et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Adwait Dongare (Pittsburgh, Pennsylvania); Artur Balanuta (Pittsburgh, Pennsylvania); Akshay Gadre (Pittsburgh, Pennsylvania); Robert Iannucci (Palo Alto, California); Swarun Kumar (Pittsburgh, Pennsylvania); Anh Luong (Pittsburgh, Pennsylvania); Revathy Narayanan (Chennai, India); Anthony Rowe (Pittsburgh, North Carolina)
ABSTRACT	A method of providing wireless communications in a wireless network can include wirelessly receiving a chirp spread-spectrum modulated signal at a first gateway device, the chirp spread-spectrum modulated signal being transmitted by a remote client device. The chirp spread-spectrum modulated signal can be demodulated at the first gateway device to provide demodulated data at the first gateway device. The demodulated data can be processed to provide an indication that a decode of a packet including the demodulated data failed. Time adjacent chirps included in the demodulated data can be combined to provide combined data at the first gateway device. A message can be transmitted from the first gateway device to a remote server responsive to an amplitude of the combined data exceeding a threshold value and the indication that the decode of the packet including the demodulated data failed.
FILED	Tuesday, June 02, 2020
APPL NO	16/890102
ART UNIT	2632 — Digital Communications
CURRENT CPC	Demodulation or Transference of Modulation From One Carrier to Another H03D 3/009 (20130101) Transmission H04B 1/12 (20130101) H04B 1/7102 (20130101) Original (OR) Class H04B 2001/6912 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/364 (20130101) H04L 27/3818 (20130101)
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10833904 — Distributed and scalable physical layer and medium access design for uplink multiuser multiple-input, multiple-output (MU-MIMO) in wireless local area network (WLAN) systems

US 10833904	Flores Miranda et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	William Marsh Rice University (Houston, Texas)
ASSIGNEE(S)	William Marsh Rice University (Houston, Texas)
INVENTOR(S)	Adriana B. Flores Miranda (Houston, Texas); Edward W. Knightly (Houston, Texas)
ABSTRACT	A client device includes a processor and an antenna. The client device obtains an announcement that specifies a winning client of a channel contention competition; identifies a group association of the client device using an identity of the winning client; transmits a preamble modulated by an entry of a preamble interference nullification matrix, the entry is based on the group association; and transmits, after transmitting the preamble, a data transmission. The preamble is transmitted at the same time as a second preamble is transmitted by a second client device.
FILED	Thursday, December 15, 2016
APPL NO	16/063031
ART UNIT	2467 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/0404 (20130101) H04B 7/0452 (20130101) Multiplex Communication H04J 11/0046 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) H04L 27/0014 (20130101) H04L 27/2611 (20130101) Original (OR) Class H04L 27/2691 (20130101) H04L 27/2692 (20130101) H04L 2027/0095 (20130101) Wireless Communication Networks H04W 74/08 (20130101) H04W 74/0841 (20130101)
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Department of Energy (DOE)

10828513 — Ionizing-radiation beam monitoring system

US 10828513	Friedman
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
INVENTOR(S)	Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT	A transmissive ionizing-radiation beam monitoring system includes an enclosure structure with at least one ultra-thin window to an incident ionizing-radiation beam, where the ultra-thin window is highly transmissive to ionizing-radiation. Embodiments include at least one thin or ultra-thin scintillator within the enclosure structure that is substantially directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam, and at least one ultraviolet (UV) illumination source within the enclosure structure facing the scintillator. Embodiments include at least one machine vision camera within the enclosure structure located out of an incident ionizing-radiation beam path and including a camera body and lens having a projection of its optical axis oriented at an angle of incidence of 45±35 degrees to a surface of the scintillator.
FILED	Friday, March 06, 2020
APPL NO	16/811471
ART UNIT	2884 — Optics
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101)
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10828596 — Promoted ammonium salt-protected activated carbon sorbent particles for removal of mercury from gas streams

US 10828596	Olson et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) Environmental Protection Agency (EPA)
APPLICANT(S)	Midwest Energy Emissions Corp. (Lewis Center, Ohio)
ASSIGNEE(S)	Midwest Energy Emissions Corp. (Lewis Center, Ohio)
INVENTOR(S)	Edwin S. Olson (Grand Forks, North Dakota); John Henry Pavlish (East Grand Forks, Minnesota); Michael J. Holmes (Thompson, North Dakota)
ABSTRACT	Promoted ammonium salt-protected activated carbon sorbent particles for removal of mercury from gas streams. A method of separating mercury from a mercury-containing gas stream includes contacting a mercury-containing gas stream with an activated carbon sorbent including promoted ammonium salt-protected activated carbon sorbent particles, to form a mercury-sorbent composition. The method also includes separating at least some of the mercury-sorbent composition from the mercury-containing gas stream, to give a separated gas.
FILED	Friday, December 16, 2016
APPL NO	15/382114
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/02 (20130101) B01D 53/06 (20130101) B01D 53/08 (20130101) Original (OR) Class B01D 53/10 (20130101) B01D 53/64 (20130101) B01D 53/83 (20130101) B01D 2253/25 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/02 (20130101) B01J 20/20 (20130101) B01J 20/0259 (20130101) B01J 20/0288 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 95/901 (20130101)
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10828621 — Supported multimetallic catalysts for oxidative dehydrogenation of alkanes

US 10828621	Bunquin et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Jeffrey C. Bunquin (Westmont, Illinois); Magali S. Ferrandon (Downers Grove, Illinois)
ABSTRACT	A catalyst for oxidative dehydrogenation of alkanes includes a substrate including an oxide; at least one promoter including a transition metal or a main group element of the periodic table; and an oxidation-active transition metal. The catalyst is multimetallic.
FILED	Monday, August 28, 2017
APPL NO	15/688699
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/34 (20130101) Original (OR) Class B01J 23/8892 (20130101) B01J 27/24 (20130101) B01J 37/024 (20130101) B01J 37/347 (20130101) Acyclic or Carbocyclic Compounds C07C 5/48 (20130101) C07C 5/48 (20130101) C07C 11/06 (20130101) C07C 2521/04 (20130101) C07C 2521/06 (20130101) C07C 2521/08 (20130101) C07C 2523/22 (20130101) C07C 2523/26 (20130101) C07C 2523/34 (20130101) C07C 2523/755 (20130101) C07C 2523/889 (20130101) C07C 2527/24 (20130101)
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10828720 — Foil-based additive manufacturing system and method

US 10828720	Tsai et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Hai-Lung Tsai (Rolla, Missouri); Yiyu Shen (Rolla, Missouri); Yingqi Li (Rolla, Missouri); Chen Chen (Rolla, Missouri)
ABSTRACT	An additive manufacturing system, method of manufacturing, and fabricated part. The system uses a material joining laser system to join together foil sheets to form a metal part. The material joining laser system can be configured to join adjacent foil sheets together in a substantially uniform manner. The manufacturing system also includes a material removal system that removes material from selected locations of the foil sheets to shape the foil sheets to correspond with selective slices of the part. The material removal system can be a laser system, such as a laser system configured to remove material from a foil sheet without removing material from an underlying layer. One embodiment involves the manufacture of amorphous alloy components.
FILED	Thursday, April 12, 2018
APPL NO	15/951268
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/22 (20130101) B23K 26/38 (20130101) B23K 26/082 (20151001) B23K 26/244 (20151001) Original (OR) Class B23K 26/0604 (20130101) B23K 2101/18 (20180801) B23K 2103/04 (20180801) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/011 (20130101) B32B 2307/702 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201)
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10828865 — Toughened and corrosion- and wear-resistant composite structures and fabrication methods thereof

US 10828865	Seals et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Security Complex and PANTEX Plant (Y-12) NNSA Critical Mission Site Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Roland D. Seals (Oak Ridge, Tennessee); Edward B. Ripley (Knoxville, Tennessee); Russell L. Hallman (Knoxville, Tennessee)
ABSTRACT	Composite structures having a reinforced material intermingled with a substrate wherein the reinforced material includes titanium monoboride, titanium diboride, or a combination thereof.
FILED	Tuesday, May 23, 2017
APPL NO	15/602684
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 35/34 (20130101) B23K 35/325 (20130101) B23K 35/327 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/05 (20190101) Original (OR) Class B32B 15/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 12/02 (20130101) C23C 18/08 (20130101) C23C 18/1204 (20130101) C23C 18/1241 (20130101) C23C 18/1275 (20130101) C23C 26/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115) Y10T 428/24826 (20150115) Y10T 428/31678 (20150401)
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10829381 — Borophenes, boron layer allotropes and methods of preparation

US 10829381	Hersam et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois); UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Mark C. Hersam (Wilmette, Illinois); Joshua D. Wood (Chicago, Illinois); Andrew J. Mannix (Chicago, Illinois); Brian T. Kiraly (Hillsboro Beach, Florida); Brandon L. Fisher (Plainfield, Illinois); Nathan P. Guisinger (Darien, Illinois)
ABSTRACT	A method of preparing an atomically-dimensioned elemental boron allotrope includes providing a substrate at a temperature greater than about 200° C.; generating elemental boron vapor from a solid elemental boron source; and contacting said substrate with said boron vapor for at least one of a rate and at a pressure sufficient to deposit on said substrate a boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension, said method under negative pressure.
FILED	Friday, May 29, 2020
APPL NO	16/886936
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 35/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101)
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10829731 — Biocatalysts for conversion of thermochemical waste streams

US 10829731	Jayakody et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Thelhawadigedara Lahiru Niroshan Jayakody (Wheat Ridge, Colorado); Gregg Tyler Beckham (Golden, Colorado)
ABSTRACT	Disclosed herein are microorganisms that have enhanced tolerance to toxic compounds found in thermochemical waste streams. Methods of utilizing carbon found in waste streams are also disclosed. Also presented herein are methods for detoxifying waste streams and methods of bioconversion of toxic waste stream materials into useful products.
FILED	Friday, January 25, 2019
APPL NO	16/258255
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/34 (20130101) Peptides C07K 14/21 (20130101) C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class
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10829745 — In vitro methods for processing lignin and other aromatic compounds

US 10829745	Donohue et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Timothy James Donohue (Middleton, Wisconsin); Daniel Leo Gall (Madison, Wisconsin); Wayne S. Kontur (Madison, Wisconsin); Hoon Kim (Madison, Wisconsin); John Ralph (Madison, Wisconsin); Daniel R. Noguera (Madison, Wisconsin); Brian Fox (Madison, Wisconsin); Craig Bingman (Fitchburg, Wisconsin)
ABSTRACT	Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, β-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The β-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.
FILED	Tuesday, August 14, 2018
APPL NO	16/103275
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/1088 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/22 (20130101) C12P 7/26 (20130101) Enzymes C12Y 114/16005 (20130101) C12Y 205/01018 (20130101)
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10829834 — Apparatus and method for recovery of material

US 10829834	Weimer et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO A Body Corporate (Denver, Colorado)
INVENTOR(S)	Alan W. Weimer (Niwot, Colorado); Aaron W. Palumbo (Denver, Colorado); Illias Hischier (Boulder, Colorado); Arto J. Groehn (Boulder, Colorado); Boris A. Chubukov (Boulder, Colorado); Scott C. Rowe (Boulder, Colorado); Richard Fisher (Broomfield, Colorado)
ABSTRACT	Systems and methods for recovering material from a gas phase are provided. Exemplary systems include a moving bed of particles onto which material can be deposited. The systems can operate in a continuous or semi-continuous mode.
FILED	Friday, March 04, 2016
APPL NO	15/741159
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Production and Refining of Metals; Pretreatment of Raw Materials C22B 5/10 (20130101) Original (OR) Class C22B 5/16 (20130101) C22B 9/04 (20130101) C22B 21/02 (20130101) C22B 26/22 (20130101)
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10829872 — Composite materials with self-regulated infrared emissivity and environment responsive fibers

US 10829872	Wang et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S)	University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Yuhuang Wang (Laurel, Maryland); Min Ouyang (Rockville, Maryland); Chuanfu Sun (College Park, Maryland); Yongxin Wang (College Park, Maryland); Shangjie Yu (College Park, Maryland)
ABSTRACT	A composite fabric having self-regulating Infrared emissivity includes meta fibers formed with optical nanostructures and an environment (temperature and/or moisture) responsive mechanism configured to adjust a relative disposition between the optical structures to control the electromagnetic coupling therebetween, thus regulating the infrared emissivity of the composite fabric to maintain a user of the fabric in a temperature/moisture comfort zone. The environment responsive mechanism may include a temperature responsive polymer layer on the fiber capable of expansion/shrinkage depending on the applied temperature, or a moisture responsive fiber changing its shape depending on the moisture level to affect spacing between the optical nanostructures.
FILED	Thursday, May 19, 2016
APPL NO	15/159666
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Woven Fabrics; Methods of Weaving; Looms D03D 1/00 (20130101) Original (OR) Class D03D 9/00 (20130101) D03D 15/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/003 (20130101) D06M 10/06 (20130101) D06M 11/74 (20130101) D06M 15/285 (20130101)
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10830278 — Halbach-array levitating passive magnetic bearing configuration

US 10830278	Post
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Richard F. Post (Walnut Creek, California)
ABSTRACT	Novel configurations of levitating passive magnetic bearing configurations are described. Such configurations can be used for the precise control of the magnitude and sign of the bearing stiffness, thereby facilitating the overall design of the system in ways that are not possible with conventional attractive or repelling bearing elements.
FILED	Friday, August 09, 2019
APPL NO	16/536882
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/0408 (20130101) F16C 32/0414 (20130101) Original (OR) Class F16C 32/0417 (20130101) F16C 32/0425 (20130101) F16C 32/0427 (20130101) Dynamo-electric Machines H02K 7/09 (20130101)
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10830442 — Segmented annular combustion system with dual fuel capability

US 10830442	Berry et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Jonathan Dwight Berry (Simpsonville, South Carolina); Stanley Kevin Widener (Greenville, South Carolina); Michael John Hughes (State College, Pennsylvania); James Scott Flanagan (Simpsonville, South Carolina)
ABSTRACT	A segmented annular combustion system with dual fuel capability includes an alternating arrangement of fuel injection modules and integrated combustor nozzles. The fuel injection module includes a bundled tube fuel nozzle portion and fuel injection lances, which are fluidly coupled via conduits to respective fuel plenums. A liquid fuel cartridge is disposed within the bundled tube fuel nozzle portion, within one of the plurality of fuel injection lances, or within both the bundled tube fuel nozzle portion and one of the plurality of fuel injection lances. A gas turbine having the segmented annular combustion system is also provided.
FILED	Tuesday, March 21, 2017
APPL NO	15/464400
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/34 (20130101) F23R 3/36 (20130101) F23R 3/46 (20130101) F23R 3/286 (20130101) Original (OR) Class F23R 3/346 (20130101)
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10830504 — Adsorption cooling system using metal organic frameworks

US 10830504	Baumann et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California); Joseph C. Farmer (Tracy, California)
ASSIGNEE(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S)	Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California); Joseph C. Farmer (Tracy, California)
ABSTRACT	An adsorptive cooling system includes: a first highly adsorptive structure positioned to receive thermal energy from a thermal energy source, including: a first substrate; and a first metal-organic framework (MOF) coupled to the first substrate and adapted for adsorbing and desorbing a refrigerant under predetermined thermodynamic conditions; a second highly adsorptive structure positioned to receive thermal energy from the thermal energy source including: a second substrate; and a second MOF coupled to the second substrate and adapted for adsorbing and desorbing a refrigerant under predetermined thermodynamic conditions; a cooling unit; and a circulation system adapted for circulating refrigerant from the first highly adsorptive structure and the second highly adsorptive structure to the cooling unit to provide cooling from the thermal energy source and to return the refrigerant to at least one of the first highly adsorptive structure and the second highly adsorptive structure.
FILED	Thursday, April 26, 2012
APPL NO	13/457331
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/08 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49359 (20150115)
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10830721 — Metal nanoparticle-decorated nanotubes for gas sensing

US 10830721	Iftime et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Methane Observation Networks with Innovative Technology to Obtain Reductions (MONITOR) System of Printed Hybrid Intelligent Nano-Chemical Sensors (SPHINCS)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Gabriel Iftime (Dublin, California); Clinton Smith (San Francisco, California); David Eric Schwartz (San Carlos, California); Yong Zhang (Millbrae, California); Vedasri Vedharathinam (Sunnyvale, California)
ABSTRACT	Disclosed herein are embodiments of compositions for gas sensing and sensors utilizing the same. In one embodiment, a composition comprises carbon nanotubes and and polymer-coated metal nanoparticles bound to the carbon nanotubes.
FILED	Friday, April 28, 2017
APPL NO	15/582172
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/0225 (20130101) B01J 20/327 (20130101) B01J 20/3204 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0018 (20130101) B22F 1/0018 (20130101) B22F 1/0062 (20130101) B22F 1/0062 (20130101) B22F 9/24 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Alloys C22C 2026/002 (20130101) C22C 2026/002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) Original (OR) Class G01N 27/126 (20130101) G01N 27/127 (20130101) G01N 33/0009 (20130101)
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10830735 — Simultaneous real-time measurement of composition, flow, attenuation, density, and pipe-wallthickness in multiphase fluids

US 10830735	Sinha et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Dipen N. Sinha (Los Alamos, New Mexico); Anirban Chaudhuri (Cary, North Carolina)
ABSTRACT	Apparatus (10) and methods for making simultaneous measurements of composition (water-cut), fluid flow, and sound attenuation in a multiphase fluid flowing (15) through a pipe (12) in real-time, using the same apparatus (10) are described. Additionally, the apparatus (10) provides real-time pipe wall thickness monitoring for observing pipe corrosion or internal deposition. Knowledge of wall thickness is necessary to correct for water-cut (oil-water composition) automatically by adjusting the liquid path length internal to the pipe (spool). The use of short duration frequency chirp excitation signals (24) enables the apparatus to provide information that can be used to extract multiple levels of information from the same measurement in multiphase fluids including the presence of a significant quantity of gas (˜60% gas volume fraction) in different flow regimes. Besides measuring steady flow, this device is useful for measurements during fast changing flows, such as for a rod-pumped well. Measurements up to about 1000 times a second can reliably be made.
FILED	Tuesday, March 20, 2018
APPL NO	16/495612
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/024 (20130101) Original (OR) Class Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/18 (20130101) G01P 5/24 (20130101)
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10830792 — Scanning tunneling thermometer

US 10830792	Chinivaranahalli Shastry et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Abhay Shankar Chinivaranahalli Shastry (Tucson, Arizona); Charles Allen Stafford (Tucson, Arizona)
ABSTRACT	Various examples are provided related to scanning tunneling thermometers and scanning tunneling microscopy (STM) techniques. In one example, a method includes simultaneously measuring conductance and thermopower of a nanostructure by toggling between: applying a time modulated voltage to a nanostructure disposed on an interconnect structure, the time modulated voltage applied at a probe tip positioned over the nanostructure, while measuring a resulting current at a contact of the interconnect structure; and applying a time modulated temperature signal to the nanostructure at the probe tip, while measuring current through a calibrated thermoresistor in series with the probe tip. In another example, a device includes an interconnect structure with connections to a first reservoir and a second reservoir; and a scanning tunneling probe in contact with a probe reservoir. Electrical measurements are simultaneously obtained for temperature and voltage applied to a nanostructure between the reservoirs.
FILED	Wednesday, March 13, 2019
APPL NO	16/352808
ART UNIT	2881 — Optics
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/10 (20130101) Original (OR) Class G01Q 60/14 (20130101) G01Q 60/58 (20130101)
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10831663 — Tracking transactions using extended memory features

US 10831663	Kahle et al.
FUNDED BY	Department of Energy (DOE) Office of Scientific and Technical Information (OSTI)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	James A. Kahle (Austin, Texas); Charles R. Johns (Austin, Texas)
ABSTRACT	An approach is disclosed that tracks memory transactions by a node. The approach establishes a transaction processing state corresponding to common virtual addresses accessed by a processing threads. Transactions are executed by the threads. A selected transaction is allowed to complete. In response to detecting a conflict in the transaction processing state, completion of a non-selected transaction is inhibited.
FILED	Monday, December 10, 2018
APPL NO	16/214856
ART UNIT	2133 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/084 (20130101) G06F 12/0828 (20130101) Original (OR) Class G06F 2212/621 (20130101) G06F 2212/656 (20130101)
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10832059 — Feature identification or classification using task-specific metadata

US 10832059	Teuton et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Jeremy R. Teuton (Pasco, Washington); Richard L. Griswold (West Richland, Washington)
ABSTRACT	Innovations in the identification or classification of features in a data set are described, such as a data set representing measurements taken by a scientific instrument. For example, a task-specific processing component, such as a video encoder, is used to generate task-specific metadata. When the data set includes video frames, metadata can include information regarding motion of image elements between frames, or other differences between frames. A feature of the data set, such as an event, can be identified or classified based on the metadata. For example, an event can be identified when metadata for one or more elements of the data set exceed one or more threshold values. When the feature is identified or classified, an output, such as a display or notification, can be generated. Although the metadata may be useable to generate a task-specific output, such as compressed video data, the identifying or classifying is not used solely in production of, or the creation of an association with, the task-specific output.
FILED	Tuesday, August 07, 2018
APPL NO	16/057408
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 16/48 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00765 (20130101) Original (OR) Class G06K 2009/00738 (20130101) G06K 2209/27 (20130101) G06K 2209/403 (20130101) Pictorial Communication, e.g Television H04N 19/25 (20141101) H04N 19/46 (20141101)
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10833283 — Insulating tunneling contact for efficient and stable perovskite solar cells

US 10833283	Huang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Jinsong Huang (Lincoln, Nebraska); Xiaopeng Zheng (Lincoln, Nebraska); Qi Wang (Lincoln, Nebraska); Yang Bai (Lincoln, Nebraska); Qingfeng Dong (Lincoln, Nebraska)
ABSTRACT	Perovskite-based photoactive devices, such as solar cells, include an insulating tunneling layer inserted between the perovskite photoactive material and the electron collection layer to reduce charge recombination and concomitantly provide water resistant properties to the device.
FILED	Thursday, September 13, 2018
APPL NO	16/130797
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0034 (20130101) H01L 51/0046 (20130101) H01L 51/0047 (20130101) H01L 51/0091 (20130101) Original (OR) Class H01L 51/442 (20130101) H01L 51/4246 (20130101) H01L 51/4286 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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10833320 — Poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester), carbon nanotubes, and sulfur nanocomposite, electrode and lithium-fulfur battery including the same

US 10833320	Liu et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Gao Liu (Piedmont, California); Guo Ai (Guangzho, China PRC); Hui Zhao (Emeryville, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Gao Liu (Piedmont, California); Guo Ai (Guangzho, China PRC); Hui Zhao (Emeryville, California)
ABSTRACT	The present invention provides for a composition of matter comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for an electrode comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for a lithium sulfur (Li—S) battery comprising: an electrode comprising poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous.
FILED	Monday, July 23, 2018
APPL NO	16/043051
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) H01M 4/136 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/606 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/661 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 2004/021 (20130101)
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10833321 — Cathode materials for lithium ion batteries

US 10833321	Wu et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Huiming Wu (Darien, Illinois); Khalil Amine (Oakbrook, Illinois); Jun Lu (Bolingbrook, Illinois)
ABSTRACT	A process of forming a coated cathode active material include preparing a cathode material precursor by co-precipitation; coating the cathode material precursor with an electrochemically inert coating material precursor by precipitation to form a coated cathode material precursor; lithiating the coated cathode material precursor with a lithium source material to form a lithiated coated cathode material precursor; and sintering the lithiated coated cathode material precursor to form a cathode active material coated with an electrochemically inert material.
FILED	Friday, March 06, 2015
APPL NO	14/641003
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/02 (20130101) C01G 49/00 (20130101) C01G 49/02 (20130101) C01G 51/04 (20130101) C01G 51/42 (20130101) C01G 53/04 (20130101) C01G 53/42 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/62 (20130101) H01M 4/131 (20130101) H01M 4/139 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0419 (20130101) H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101)
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10833332 — Systems and methods for scale-up synthesis multi-layered Pt-skin nanoparticle catalysts

US 10833332	Stamenkovic et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Vojislav Stamenkovic (Naperville, Illinois); Gregory K. Krumdick (Homer Glen, Illinois); Rongyue Wang (Westmont, Illinois); Nenad Markovic (Hinsdale, Illinois); Krzysztof Z. Pupek (Plainfield, Illinois)
ABSTRACT	A method for scaled-up synthesis of PtNi nanoparticles. Synthesizing a Pt nanoparticle catalyst comprises the steps of: synthesizing PtNi nanoparticles, isolating PtNi/substrate nanoparticles, acid leaching the PtNi/substrate, and annealing the leached PtNi/substrate nanoparticles, and forming a Pt-skin on the PtNi/substrate nanoparticles.
FILED	Friday, June 01, 2018
APPL NO	15/996297
ART UNIT	1796 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) H01M 4/926 (20130101) H01M 4/8657 (20130101) Original (OR) Class
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10833345 — Materials for high-performance aqueous organic redox flow batteries

US 10833345	Narayan et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S)	Sri Narayan (Arcadia, California); Surya G. Prakash (Hacienda Heights, California); Robert Aniszfeld (Los Angeles, California); Bo Yang (Los Angeles, California); Lena Hoober-Burkhardt (Los Angeles, California); Sankarganesh Krishnamoorthy (Los Angeles, California); Advaith Murali (Los Angeles, California); Archith Nirmalchandar (Los Angeles, California)
ABSTRACT	Quinones and related compounds for use in flow batteries are provided. Many of these compounds are found to mitigate the effects of crossover in a flow battery. Other structure for improving battery performance is provided.
FILED	Monday, October 02, 2017
APPL NO	15/723071
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 2008/1095 (20130101) H01M 2250/10 (20130101) H01M 2300/0014 (20130101) H01M 2300/0082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101)
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10833360 — Protective anode coatings for high energy batteries

US 10833360	Hegde et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Vinay Ishwar Hegde (Chicago, Illinois); David H. Snydacker (Evanston, Illinois); Christopher M. Wolverton (Evanston, Illinois)
ABSTRACT	Materials for coating a metal anode in a high energy battery, anodes coated with the materials, and batteries incorporating the coated anodes are provided. Also provided are batteries that utilize the materials as electrolytes. The coatings, which are composed of binary, ternary, and higher order metal and/or metalloid oxides, nitrides, fluorides, chlorides, bromides, sulfides, and carbides limit the reactions between the electrolyte and the metal anode in a battery, thereby improving the performance of the battery, relative to a battery that employs a bare anode.
FILED	Wednesday, March 08, 2017
APPL NO	16/081533
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101)
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10833361 — Standalone sulfide based lithium ion-conducting glass solid electrolyte and associated structures, cells and methods

US 10833361	Visco et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	PolyPlus Battery Company (Berkeley, California)
ASSIGNEE(S)	PolyPlus Battery Company (Berkeley, California)
INVENTOR(S)	Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California)
ABSTRACT	A standalone lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery by providing a high degree of lithium ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner.
FILED	Tuesday, October 16, 2018
APPL NO	16/161720
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Manufacture, Shaping, or Supplementary Processes C03B 17/06 (20130101) C03B 17/064 (20130101) C03B 17/067 (20130101) C03B 23/037 (20130101) C03B 23/245 (20130101) C03B 33/0235 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/19 (20130101) C03C 3/321 (20130101) C03C 4/18 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101)
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10833374 — In-situ x-ray scatter imaging of battery electrodes

US 10833374	Rose-Petruck et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Brown University (Providence, Rhode Island)
ASSIGNEE(S)	BROWN UNIVERSITY (Providence, Rhode Island)
INVENTOR(S)	Christoph Rose-Petruck (Providence, Rhode Island); Brian Sheldon (Brookline, Massachusetts); Alexandra Stephan (Providence, Rhode Island); Ravi Kumar (Providence, Rhode Island); Francicso Schunk (Providence, Rhode Island)
ABSTRACT	A method and apparatus for in-situ x-ray scatter imaging of battery electrodes. An apparatus includes an X-ray source, a grid, the grid comprising stainless steel wires with uniform spacing, and a cell, the X-ray source directing a beam of energy through the metal grid and components of the cell, the cell blurring a previously sharp projection of grid wires on an image detector. A method includes providing a Spatial Frequency Heterodyne Imaging system, providing a grid, providing a cell, generating X-rays from the Spatial Frequency Heterodyne Imaging system that pass through components of the cell and the grid, and detecting a scatter image from the X-rays.
FILED	Friday, November 03, 2017
APPL NO	15/803458
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/201 (20130101) G01N 23/2076 (20130101) G01N 23/20025 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4285 (20130101) Original (OR) Class
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10833436 — Interdigitated power connector

US 10833436	Coteus et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Paul W. Coteus (Yorktown, New York); Andrew Ferencz (Southborough, Massachusetts); Shawn A. Hall (Pleasantville, New York); Todd E. Takken (Brewster, New York)
ABSTRACT	An electrical connector carries large amounts of electrical current between two circuit boards with low resistance and low self-inductance by means of an interdigitated anode and cathode, thereby providing low dynamic voltage loss. The connector also may include, near where power will be consumed, an interposer board with on-board capacitance to provide even lower dynamic voltage loss. The connector has application to delivering low-voltage, high-current power from a power supply on a first board to electronics on a second board: the low resistance provides low voltage drop for a load current that is constant, while the low inductance and the capacitors provide low voltage fluctuation for a load current that changes. These issues are of great importance, for example, in designing high-performance computers.
FILED	Sunday, December 24, 2017
APPL NO	15/853806
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/30 (20130101) H01R 4/363 (20130101) H01R 12/73 (20130101) H01R 12/515 (20130101) Original (OR) Class H01R 12/523 (20130101) H01R 12/7088 (20130101) H01R 13/6625 (20130101)
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10833678 — Performance CMOS voltage level-up shifter circuit topology using pre-drive pull-up transistors

US 10833678	Armstrong
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	Paul Armstrong (Fort Collins, Colorado)
ABSTRACT	In a first example a voltage level-shifting device includes a level-shifting stage circuit. The level-shifting stage circuit includes a first level-shifting inverter circuit to invert a buffered input signal to drive a first internal node, a second level-shifting inverter circuit to invert a buffered inverted input signal to drive a second internal node, a first pre-drive circuit that receives the buffered inverted input signal, and drives the second internal node based on the state of the buffered inverted input signal, and a second pre-drive circuit that receives the buffered input signal, and drives the first internal node based on the state of the buffered input signal.
FILED	Tuesday, July 30, 2019
APPL NO	16/525913
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/0948 (20130101) Original (OR) Class H03K 19/17784 (20130101)
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10833954 — Extracting dependencies between network assets using deep learning

US 10833954	Carroll et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Thomas E. Carroll (Richland, Washington); Satish Chikkagoudar (Richland, Washington); Thomas W. Edgar (Richland, Washington); Kiri J. Oler (Tacoma, Washington); Kristine M. Arthur (West Lafayette, Indiana); Daniel M. Johnson (Kennewick, Washington); Lars J. Kangas (West Richland, Washington)
ABSTRACT	A network analysis tool receives network flow information and uses deep learning—machine learning that models high-level abstractions in the network flow information—to identify dependencies between network assets. Based on the identified dependencies, the network analysis tool can discover functional relationships between network assets. For example, a network analysis tool receives network flow information, identifies dependencies between multiple network assets based on evaluation of the network flow information, and outputs results of the identification of the dependencies. When evaluating the network flow information, the network analysis tool can pre-process the network flow information to produce input vectors, use deep learning to extract patterns in the input vectors, and then determine dependencies based on the extracted patterns. The network analysis tool can repeat this process so as to update an assessment of the dependencies between network assets on a near real-time basis.
FILED	Wednesday, November 19, 2014
APPL NO	14/548159
ART UNIT	2126 — AI & Simulation/Modeling
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 41/14 (20130101) H04L 41/16 (20130101) Original (OR) Class H04L 43/026 (20130101)
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Department of Homeland Security (DHS)

10829770 — Fusion proteins containing luciferase and a polypeptide of interest

US 10829770	Puckette et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	Michael Puckette (Waterford, Connecticut); Max V. Rasmussen (Guilford, Connecticut)
ABSTRACT	Polynucleotides encoding fusion proteins contain a secretable luciferase fused to a modified polypeptide of interest are disclosed. The polypeptide of interest has been modified to remove a native N-terminal secretion sequence and has been replaced by the secretable luciferase. One example of a modified polypeptide of interest is interferon. The polynucleotides and fusion proteins have biotherapeutic, diagnostic, and quality control applications in biotechnological, medical, and veterinary fields. Methods for producing the secretable fusion protein are also disclosed.
FILED	Monday, September 16, 2019
APPL NO	16/571616
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/21 (20130101) Peptides C07K 14/00 (20130101) C07K 14/56 (20130101) C07K 14/705 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/00 (20130101) C12N 15/63 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101)
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10831889 — Secure memory implementation for secure execution of virtual machines

US 10831889	Hall et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	William E. Hall (Clinton, Connecticut); Guerney D. H. Hunt (Yorktown Heights, New York); Ronald N. Kalla (Round Rock, Texas); Jentje Leenstra (Bondorf, Germany); Paul Mackerras (Weston, Australia); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas)
ABSTRACT	A system, a method, and a computer program product for secure memory implementation for secure execution of virtual machines are provided. Data is processed in a first mode and a second mode, and commands are sent to a chip interconnect bus using real addresses, wherein the chip interconnect bus transports a number of bits for the real addresses. A memory controller is operatively coupled to a memory component. A secure memory range is specified by using range registers. If the real address is detected to be in the secure memory range to match a memory component address, a real address bit is set. If the real address is in the memory address hole, a security access violation is detected. If the real address is not in the secure address range and the real address bit is set, the security access violation is detected.
FILED	Tuesday, August 13, 2019
APPL NO	16/539537
ART UNIT	2495 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 9/45558 (20130101) G06F 12/1441 (20130101) G06F 13/364 (20130101) G06F 13/404 (20130101) G06F 21/53 (20130101) G06F 21/78 (20130101) G06F 21/556 (20130101) Original (OR) Class G06F 21/6281 (20130101) G06F 2009/45587 (20130101) G06F 2212/1052 (20130101) G06F 2221/034 (20130101)
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10831940 — Utility situational awareness system

US 10831940	Marean et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S)	GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
INVENTOR(S)	James Marean (Binghamton, New York); William Gale (Palm Coast, Florida)
ABSTRACT	A method and software-implemented system that provides a situational awareness tool for infrastructure operators and government agencies to assess vulnerabilities, and optimize the deployment of prevention and mitigation technologies. The invention automatically obtains current supply information from each of more than one participating utility provider. The supply information from the different sources is standardized and combined with geographic information to provide a building level map of utility service and outages. The service locations, e.g., residential and commercial buildings, are represented as building polygons corresponding to building footprint, and can be color-coded to indicate service status.
FILED	Thursday, December 22, 2016
APPL NO	15/388314
ART UNIT	2127 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 30/13 (20200101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0637 (20130101) G06Q 50/06 (20130101)
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10832366 — Wireless, intrusion-resistant customs declaration service

US 10832366	Maher
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	David Maher (Washington, District of Columbia)
ABSTRACT	Mobile collection and vetting of user supplied information is described. The systems, techniques, devices, methods, and approaches described herein can be used to obtain, validate, and vet information, such as customs information, in a mobile environment. In embodiments, methods comprise receiving information input via a mobile device. The information is encapsulated by an intermediate to escort the information through a firewall to the database. In response to vetting the information to determine if it meets one or more criteria, the method involves creating a record associated with a unique identifier, information that bio-identifies a user, or an indication of a determination that results from the vetting. In this embodiment, the method includes generating an electronic receipt for communication to the mobile device, the electronic receipt including the unique identifier.
FILED	Wednesday, January 29, 2020
APPL NO	16/776170
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 16/83 (20190101) G06F 16/2228 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Original (OR) Class
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10834482 — Systems and methods for integrating first responder technologies

US 10834482	Speicher et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	Norman Speicher (Washington, District of Columbia); Donald McGarry (Reston, Virginia); Brian Wilkins (Reston, Virginia)
ABSTRACT	Various embodiments of the present invention are directed towards a system and method relating to Next Generation First Responder (NGFR) modular and scalable systems capable of easily integrating various components via open standards and interfaces. For example, a wearable on-body first responder system includes at least one sensor configured to identify sensor information, a controller configured to provide a first responder mobile support architecture and that is configured to interface with the at least one sensor. The controller is configured to collect and distribute the sensor information, and an input/output (I/O) device is configured to interface with the controller and present the sensor information to a user of the on-body first responder system.
FILED	Tuesday, December 04, 2018
APPL NO	16/209636
ART UNIT	2685 — Selective Communication
CURRENT CPC	Electric Digital Data Processing G06F 1/26 (20130101) G06F 1/163 (20130101) G06F 13/20 (20130101) Transmission H04B 1/385 (20130101) Selecting H04Q 9/00 (20130101) Original (OR) Class H04Q 2209/00 (20130101) H04Q 2209/20 (20130101) H04Q 2209/40 (20130101) H04Q 2209/43 (20130101) H04Q 2209/80 (20130101) H04Q 2209/88 (20130101) Wireless Communication Networks H04W 84/18 (20130101)
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National Aeronautics and Space Administration (NASA)

10828221 — Wearable, self-locking shape memory alloy (SMA) actuator cartridge

US 10828221	Holschuh et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Bradley T. Holschuh (North Oaks, Minnesota); Dava J. Newman (Marblehead, Massachusetts); Giacomo Gatto (Rome, Italy); Luca Levrino (Turin, Italy)
ABSTRACT	Described embodiments provide a shape memory alloy (SMA) cartridge for use in providing controllable compression. The SMA cartridge includes first and second end caps, each of the first and second end caps being coupled to a passive material. One or more SMA coils extend between the first and second end caps. The SMA coils have a trained state and a deformed state, where the SMA coils are in the deformed state when a stimulus is provided thereto and the SMA coils are in the trained state when the stimulus is removed therefrom. The first end cap and the second end cap include a locking mechanism to automatically lock the first and second end caps in a fixed position relative to one another when the SMA coils are contracted.
FILED	Thursday, November 05, 2015
APPL NO	15/518356
ART UNIT	3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Outerwear; Protective Garments; Accessories A41D 31/00 (20130101) A41D 2400/32 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/03 (20130101) A61F 5/028 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/008 (20130101) Original (OR) Class A61H 2201/165 (20130101) A61H 2205/10 (20130101) A61H 2209/00 (20130101)
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10828400 — Low temperature, nanostructured ceramic coatings

US 10828400	Cho
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Binghamton, New York)
INVENTOR(S)	Junghyun Cho (Vestal, New York)
ABSTRACT	A substrate subject to degradation at temperatures above 100° C. is coated with a nanostructured ceramic coating having a thickness in excess of 100 nm, formed on a surface of the substrate, wherein a process temperature for deposition of the nanostructured coating does not exceed 90° C. The coating may be photocatalytic, photovoltaic, or piezoelectric. The coating, when moistened and exposed to ultraviolet light or sunlight, advantageously generates free radicals, which may be biocidal, deodorizing, or assist in degradation of surface deposits on the substrate after use. The substrate may be biological or organic, and may have a metallic or conductive intermediate layer.
FILED	Tuesday, June 09, 2015
APPL NO	14/734520
ART UNIT	1786 — Miscellaneous Articles, Stock Material
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/106 (20130101) A61L 31/16 (20130101) A61L 31/088 (20130101) Original (OR) Class A61L 2300/404 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/14 (20130101) B29C 2035/0827 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 1/725 (20130101) C02F 2201/326 (20130101) C02F 2303/02 (20130101) C02F 2305/08 (20130101) C02F 2305/10 (20130101) C02F 2307/12 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) C08J 7/14 (20130101) C08J 2323/22 (20130101) C08J 2331/04 (20130101) C08J 2383/04 (20130101) C08J 2389/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 442/2525 (20150401)
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10829511 — Molecular recognition systems with pyrimidine analog pairing

US 10829511	Benner et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Steven A Benner (Gainesville, Florida); Shuichi Hoshika (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S)	Steven A Benner (Gainesville, Florida); Shuichi Hoshika (Gainesville, Florida)
ABSTRACT	This invention covers oligonucleotide analogs that fold in part by having a segment of consecutive pyrimidine analogs form pyrimidine analog:pyrimidine analog pairs with another a segment of consecutive pyrimidine analogs segment, and where the segments pair by pyrimidine analog:pyrimidine analog “skinny” pairing. This pairing retains hydrogen bonding complementarity seen in standard DNA.
FILED	Friday, August 02, 2019
APPL NO	16/530600
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Original (OR) Class
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10829857 — Gas phase alloying for wire fed joining and deposition processes

US 10829857	Brice
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S)	Craig A. Brice (Yorktown, Virginia)
ABSTRACT	Gas is introduced into molten metal during an additive metal fabrication process and/or during a metal fusion process. The gas may comprise a process gas that flows through a tubular feed wire. The amount of process gas introduced can be controlled to vary the composition and/or material properties of metal deposits formed from a molten metal. Material properties such as yield strength, hardness, and fracture toughness can be increased or decreased in specific regions to provide material property gradients that closely correspond to expected requirements of components fabricated utilizing additive and/or fusion processes.
FILED	Wednesday, March 12, 2014
APPL NO	14/206231
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0006 (20130101) B23K 15/06 (20130101) B23K 15/0086 (20130101) B23K 15/0093 (20130101) B23K 2103/14 (20180801) Alloys C22C 14/00 (20130101) C22C 38/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/30 (20130101) Original (OR) Class
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Department of Commerce (DOC)

10828664 — Device and method for making shear-aligned, solvent-cast films

US 10828664	Shelton et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) NIST Center for Neutron Research (NCNR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Cameron Shelton (Bear, Delaware); Thomas H. Epps, III (Bear, Delaware)
ASSIGNEE(S)	UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S)	Cameron Shelton (Bear, Delaware); Thomas H. Epps, III (Bear, Delaware)
ABSTRACT	A coating head includes a coating device and at least a first flexible blade that is capable of being shaped into contact with a solvent-containing film on a substrate upon pressing the first flexible blade against the film, thereby providing contact between the blade and the film over a contact distance when the coating head is drawn over the substrate. The coating device and the blade are separated by a spacing distance such that partial loss of solvent occurs from a starting film formed on the substrate by the coating device as the coating head is drawn over the substrate, the partial solvent loss forming the solvent-containing film. A method of producing a film having a hierarchical structure includes drawing a coating head across a substrate to form on the substrate via the coating device a starting film including a solvent and a material for forming the hierarchical structure.
FILED	Thursday, December 08, 2016
APPL NO	15/776289
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Apparatus for Applying Fluent Materials to Surfaces, in General B05C 11/045 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/42 (20130101) Original (OR) Class B05D 2252/02 (20130101) Optical Elements, Systems, or Apparatus G02B 5/30 (20130101)
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10830692 — System and method to measure dissolved gases in liquid

US 10830692	Wang et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) National Science Foundation (NSF) Directorate of Geosciences (GEO) Division of Ocean Sciences (OCE)
APPLICANT(S)	Woods Hole Oceanographic Institution (Woods Hole, Massachusetts)
ASSIGNEE(S)	WOODS HOLE OCEANOGRAPHIC INSTITUTION (Woods Hole, Massachusetts)
INVENTOR(S)	Zhaohui ‘Aleck’ Wang (N. Falmouth, Massachusetts); Frederick N. Sonnichsen (Woods Hole, Massachusetts)
ABSTRACT	A high-resolution in situ sensing system and method for providing continuous measurements of at least one dissolved analyte including a sample processing cell having at least a first conduit defining a first passage with at least one selectively-permeable wall capable of passing a portion of the sample liquid into a processing, fluid. The at least one selectively-permeable wall substantially resists flow of another portion of the sample liquid therethrough. Processing fluid is directed through the first conduit while moving the sample liquid and the reagent fluid relative to each other in one of a stationary, concurrent or a countercurrent flow relationship to achieve either partial or full equilibration between the sample liquid and processing fluid to generate at least partially equilibrated reagent fluid and a processed sample in a substantially continuous manner.
FILED	Saturday, September 01, 2018
APPL NO	16/120248
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 15/06 (20130101) G01N 21/05 (20130101) G01N 21/80 (20130101) G01N 21/314 (20130101) Original (OR) Class G01N 21/783 (20130101) G01N 31/221 (20130101) G01N 33/18 (20130101) G01N 33/1886 (20130101) G01N 33/1893 (20130101) G01N 2201/0212 (20130101) G01N 2201/0216 (20130101) G01N 2201/0218 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/235 (20150115) Y10T 436/255 (20150115)
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10830747 — System and method for predicting fatigue strength of alloys

US 10830747	Agrawal et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ankit Agrawal (Evanston, Illinois); Alok Choudhary (Chicago, Illinois)
ABSTRACT	Systems and methods include a predictor module configured to receive an input, e.g., composition parameters and processing parameters. A processor processes the input to predict a material property, e.g., fatigue strength, of an alloy based on the input. The processor outputs the predicted fatigue strength of the alloy for display.
FILED	Wednesday, October 25, 2017
APPL NO	15/793376
ART UNIT	2861 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/20 (20130101) G01N 33/202 (20190101) Original (OR) Class G01N 33/2022 (20190101) G01N 33/2025 (20190101) G01N 33/2028 (20190101) G01N 2203/0073 (20130101) G01N 2203/0218 (20130101) G01N 2203/0246 (20130101) Electric Digital Data Processing G06F 16/2465 (20190101) G06F 30/20 (20200101) G06F 30/333 (20200101)
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Department of Agriculture (USDA)

10828246 — Effective hair styling compositions and processes

US 10828246	Yang et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S)	NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S)	Yiqi Yang (Lincoln, Nebraska); Helan Xu (Lincoln, Nebraska); Kaili Song (Lincoln, Nebraska)
ABSTRACT	This disclosure relates to hair styling compositions and processes, and more particularly to compositions for disentangling or crosslinking hair that are useful in hair styling processes.
FILED	Monday, October 03, 2016
APPL NO	15/284336
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Hairdressing or Shaving Equipment; Equipment for Cosmetics or Cosmetic Treatments, e.g for Manicuring or Pedicuring A45D 7/06 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/24 (20130101) A61K 8/37 (20130101) A61K 8/41 (20130101) A61K 8/42 (20130101) A61K 8/44 (20130101) A61K 8/46 (20130101) Original (OR) Class A61K 8/345 (20130101) A61K 8/362 (20130101) A61K 8/447 (20130101) A61K 8/463 (20130101) A61K 2800/80 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 5/04 (20130101) A61Q 5/06 (20130101)
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10830750 — Functional soil maps

US 10830750	Owens et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Phillip Ray Owens (West Lafayette, Indiana); Hans Edwin Winzeler (Gettysburg, Pennsylvania); Zamir Libohova (West Lafayette, Indiana); Jenette Ashetkar (West Lafayette, Indiana)
ABSTRACT	Embodiments of the present disclosure relate generally to system and methods for generating functional soil maps. The systems and methods are configured to determine soil information for an area of interest; determine an elevation model for the area of interest; determine terrain attributes for the area of interest based on the elevation model; determine a relationship between the soil information and the terrain attributes for the area of interest; and generate a functional soil map based at least in part on the relationship between the soil information and the terrain attributes for the area of interest. In an embodiment, the systems and methods can be used to improve management strategies for crops and other land management regions.
FILED	Thursday, May 21, 2015
APPL NO	14/718856
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/24 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/02 (20130101)
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Environmental Protection Agency (EPA)

10828596 — Promoted ammonium salt-protected activated carbon sorbent particles for removal of mercury from gas streams

US 10828596	Olson et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) Environmental Protection Agency (EPA)
APPLICANT(S)	Midwest Energy Emissions Corp. (Lewis Center, Ohio)
ASSIGNEE(S)	Midwest Energy Emissions Corp. (Lewis Center, Ohio)
INVENTOR(S)	Edwin S. Olson (Grand Forks, North Dakota); John Henry Pavlish (East Grand Forks, Minnesota); Michael J. Holmes (Thompson, North Dakota)
ABSTRACT	Promoted ammonium salt-protected activated carbon sorbent particles for removal of mercury from gas streams. A method of separating mercury from a mercury-containing gas stream includes contacting a mercury-containing gas stream with an activated carbon sorbent including promoted ammonium salt-protected activated carbon sorbent particles, to form a mercury-sorbent composition. The method also includes separating at least some of the mercury-sorbent composition from the mercury-containing gas stream, to give a separated gas.
FILED	Friday, December 16, 2016
APPL NO	15/382114
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/02 (20130101) B01D 53/06 (20130101) B01D 53/08 (20130101) Original (OR) Class B01D 53/10 (20130101) B01D 53/64 (20130101) B01D 53/83 (20130101) B01D 2253/25 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/02 (20130101) B01J 20/20 (20130101) B01J 20/0259 (20130101) B01J 20/0288 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 95/901 (20130101)
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10830684 — Reproducible reference standards for filter-based measurements of carbonaceous aerosols found in environmental samples

US 10830684	Solomon et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia)
ASSIGNEE(S)	GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia)
INVENTOR(S)	Paul A. Solomon (Henderson, Nevada); Anthony D. A. Hansen (Berkeley, California); Anna-Marie Hyatt (Las Vegas, Nevada)
ABSTRACT	The method of the invention provides a simple, reproducible reference, or set of reference standards, as a validation of a calibration standard for filter-based measurements of light absorbing aerosol particles (black carbon and brown carbon) and organic carbon and elemental carbon particles found in indoor and outdoor environments, and in emission streams. The set of reference standards comprise grayscale images deposited by a mist or print at a known density on a substrate material. The reference standards may be made by a printer using as a substrate either paper or another material such as glass fiber, quartz fiber, polypropylene, or cellulose.
FILED	Monday, October 15, 2018
APPL NO	16/160637
ART UNIT	2896 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/322 (20130101) C09D 11/324 (20130101) C09D 11/328 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 15/0618 (20130101) Original (OR) Class G01N 21/278 (20130101) G01N 2001/2893 (20130101) G01N 2015/0046 (20130101) Electrography; Electrophotography; Magnetography G03G 15/16 (20130101) G03G 15/55 (20130101) G03G 21/20 (20130101)
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National Security Agency (NSA)

10831629 — Multi-agent plan recognition

US 10831629	Riabov et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York)
ABSTRACT	Techniques for solving a multi-agent plan recognition problem are provided. In one example, a computer-implemented method comprises transforming, by a device operatively coupled to a processor, a problem model and an at least partially ordered sequence of observations into an artificial intelligence planning problem through a transform algorithm. The problem model can comprises a domain description from a plurality of agents and a durative action. Furthermore, at least one of the observations of the at least partially ordered sequence of observations can be a condition that changes over time. The computer-implemented method further comprises determining, by the device, plan information using an artificial intelligence planner on the artificial intelligence planning problem. The computer-implemented method further comprises translating, by the device, the plan information into information indicative of a solution to the artificial intelligence planning problem.
FILED	Friday, January 27, 2017
APPL NO	15/418452
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 9/4862 (20130101) G06F 11/302 (20130101) Original (OR) Class G06F 11/3006 (20130101) G06F 11/3438 (20130101) G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101)
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10833016 — Semiconductor device including superconducting metal through-silicon-vias and method of making the same

US 10833016	Abraham et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	David W. Abraham (Croton, New York); John M. Cotte (New Fairfield, Connecticut)
ABSTRACT	A semiconductor structure and methods of forming the semiconductor structure generally includes providing a thermocompression bonded superconducting metal layer sandwiched between a first silicon substrate and a second silicon substrate. The second substrate includes a plurality of through silicon vias to the thermocompression bonded superconducting metal layer. A second superconducting metal is electroplated into the through silicon vias using the thermocompression bonded superconducting metal layer as a bottom electrode during the electroplating process, wherein the filling is from the bottom upwards.
FILED	Tuesday, December 11, 2018
APPL NO	16/215913
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02068 (20130101) H01L 21/2885 (20130101) H01L 21/32058 (20130101) H01L 21/32133 (20130101) H01L 21/76877 (20130101) H01L 21/76898 (20130101) H01L 23/481 (20130101) H01L 23/53285 (20130101) Original (OR) Class H01L 24/08 (20130101) H01L 24/89 (20130101) H01L 25/50 (20130101) H01L 25/0657 (20130101) H01L 2224/08146 (20130101) H01L 2224/80203 (20130101) H01L 2225/06541 (20130101)
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Department of Transportation (USDOT)

10830049 — Leading edge hybrid cavities and cores for airfoils of gas turbine engine

US 10830049	Clum et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Carey Clum (East Hartford, Connecticut); Dominic J. Mongillo (West Hartford, Connecticut)
ABSTRACT	Airfoils having a leading edge, a trailing edge, a first end, and a second end with a leading edge hybrid skin core cavity formed within the airfoil extending from the first end to the second end proximate the leading edge, the cavity having a hot wall and a cold wall. The cavity has a variable height-to-width ratio in a direction from the first end to the second end, with a first aspect ratio proximate the first end and a second aspect ratio proximate the second end with the height defined as a maximum distance between the hot wall and the cold wall and the width is defined as an arc length of the cold wall.
FILED	Tuesday, May 02, 2017
APPL NO	15/584119
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Foundry Moulding B22C 9/103 (20130101) B22C 13/10 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/20 (20130101) F01D 5/141 (20130101) Original (OR) Class F01D 5/147 (20130101) F01D 5/187 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/24 (20130101) F05D 2240/301 (20130101) F05D 2240/303 (20130101) F05D 2240/304 (20130101) F05D 2240/307 (20130101) F05D 2250/60 (20130101) F05D 2250/231 (20130101) F05D 2250/711 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) F05D 2260/205 (20130101) F05D 2300/20 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

10828304 — Compositions and methods for white to beige adipogenesis

US 10828304	Cooper et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	University of South Florida (Tampa, Florida); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	University of South Florida (Tampa, Florida); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Denise Ratzlaff Cooper (St. Petersburg, Florida); Ryan Adam Kirchoffer (Ocala, Florida); Robert Pleasants Sparks (Urbana, Illinois); Wayne Charles Guida (Saint Pete Beach, Florida)
ABSTRACT	Disclosed herein are compositions and methods for transitioning or converting a white adipocyte to a beige adipocyte. The compositions and methods may be used in the treatment of obesity. In some embodiments, the compositions include a compound selected from DC677 and DC761.
FILED	Thursday, May 14, 2020
APPL NO	16/874226
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/473 (20130101) A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101)
VIEW PATENT	@ USPTO: Full Text PDF

European Union (EU)

10830772 — Detection method and kit

US 10830772	Lettieri et al.
FUNDED BY	European Union (EU)
APPLICANT(S)	The European Union, represented by the European Commission (Brussels, Belgium)
ASSIGNEE(S)	THE EUROPEAN UNION, REPRESENTED BY THE EUROPEAN COMMISSION (Brussels, Belgium)
INVENTOR(S)	Teresa Lettieri (Gavirate, Italy); Valentina Elisabetta Viviana Ferrero (Turin, Italy)
ABSTRACT	Uses of ethyl 5,11-dihydroindolo[3,2-b]carbazole-6-carboxylate as a fluorescent ligand probe, preferably in a binding assay for quantitative analysis in combination with a recombinant aryl hydrocarbon receptor (AhR) protein. A method for detection or quantitative analysis of suspected aryl hydrocarbon receptor (AhR) ligands in a sample, the method comprising the steps of: (a) providing a sample possibly containing at least one known or unknown AhR ligand; (b) mixing said sample with a composition comprising a recombinant AhR protein bound to ethyl 5,11-dihydroindolo[3,2-b]carbazole-6-carboxylate; and (c) determining the presence or the total amount of said at least one known or unknown AhR ligand in the sample by fluorescence spectroscopy. Use e.g. for screening of unknown compounds to determine their binding ability to AhR; for analyzing unknown chemical mixtures to assess the presence of ligands able to bind to AhR; for screening of Polycyclic Aromatic Hydrocarbon (PAHs) from water, food or sediment; for screening of PAHs or dioxin-like compounds in water, food or sediment; for testing for pollutant removal in water and waste water treatment plants; for testing for water reuse; for testing the presence of dioxin-like compounds in incinerator plants; or for testing of bodily fluids of humans or animals exposed to PAHs or dioxin-like compounds.
FILED	Thursday, March 03, 2016
APPL NO	15/556148
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 2333/705 (20130101) G01N 2500/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10828513 — Ionizing-radiation beam monitoring system

US 10828513	Friedman
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S)	Integrated Sensors, LLC (Ottawa Hills, Ohio)
INVENTOR(S)	Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT	A transmissive ionizing-radiation beam monitoring system includes an enclosure structure with at least one ultra-thin window to an incident ionizing-radiation beam, where the ultra-thin window is highly transmissive to ionizing-radiation. Embodiments include at least one thin or ultra-thin scintillator within the enclosure structure that is substantially directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam, and at least one ultraviolet (UV) illumination source within the enclosure structure facing the scintillator. Embodiments include at least one machine vision camera within the enclosure structure located out of an incident ionizing-radiation beam path and including a camera body and lens having a projection of its optical axis oriented at an angle of incidence of 45±35 degrees to a surface of the scintillator.
FILED	Friday, March 06, 2020
APPL NO	16/811471
ART UNIT	2884 — Optics
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10830048 — Gas turbine rotor disk having scallop shield feature

US 10830048	Shaughnessy
FUNDED BY
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Kyle F. Shaughnessy (Manchester, Connecticut)
ABSTRACT	A rotor disk for a gas turbine engine is disclosed. In various embodiments, the rotor disk includes a rim portion disposed about a central axis; a blade post disposed proximate the rim portion, the blade post having a first branch and a second branch; and a first scallop disposed within the rim portion, between and radially inward of the first branch and the second branch.
FILED	Friday, February 01, 2019
APPL NO	16/265399
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/06 (20130101) Original (OR) Class F01D 5/225 (20130101) F01D 5/3007 (20130101) Non-positive-displacement Pumps F04D 29/329 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10830078 — Shaft seal assembly for a turbine engine

US 10830078	Fiore et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Brad E. Fiore (Vernon, Connecticut); James B. Coffin (Windsor, Connecticut); Christopher M. Valva (Manchester, Connecticut)
ABSTRACT	An assembly is provided for a turbine engine. This turbine engine assembly includes a tower shaft rotatable about an axis, an engine component rotatable with the tower shaft about the axis, and a seal assembly. The engine component extends axially along the axis to an end surface. The seal assembly includes a carbon seal element, where the carbon seal element circumscribes the tower shaft and axially engages the end surface.
FILED	Friday, September 14, 2018
APPL NO	16/131145
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Original (OR) Class F01D 25/16 (20130101) F01D 25/183 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) F05D 2240/60 (20130101) F05D 2260/98 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10830080 — Halo seal separate scallop support

US 10830080	DiFrancesco et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Michael L. DiFrancesco (Waterbury, Connecticut); Conway Chuong (Manchester, Connecticut)
ABSTRACT	A seal arrangement may comprise a seal comprising an outer ring, a shoe, and an arm extending between the shoe and the outer ring, wherein the shoe moves relative to the outer ring via the arm, a seal ring adjacent the seal, and a support plate disposed between the seal and the seal ring, wherein the support plate moves together with the shoe in a radial direction relative to the seal ring.
FILED	Friday, September 28, 2018
APPL NO	16/147213
ART UNIT	3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/441 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10830086 — Cam isolation system for gas turbine engine compressor section

US 10830086	Pratt et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	William S. Pratt (West Hartford, Connecticut); Paul W. Duesler (Manchester, Connecticut)
ABSTRACT	A cam isolation system for a gas turbine engine compressor actuator includes a torque tube. The system also includes a cam bracket operatively coupled to an engine case structure, the cam bracket defining a slot. The system further includes an actuator bracket operatively coupled to the torque tube at a first end of the actuator bracket, the actuator bracket having a pin disposed within the slot of the cam bracket.
FILED	Wednesday, July 18, 2018
APPL NO	16/038344
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Original (OR) Class F01D 25/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10833749 — Communication system and method using layered construction of arbitrary unitary matrices

US 10833749	Robinson
FUNDED BY
APPLICANT(S)	Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S)	Rampart Communications, Inc. (Annapolis, Maryland)
INVENTOR(S)	Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT	A method includes generating, via a first processor of a first compute device, symbols based on an incoming data and decomposing a unitary matrix of size N×N by: 1) applying a permutation to each symbol using a permutation matrix, to produce permuted symbols, and 2) transforming each symbol using at least one primitive transformation matrix of size M×M, M being smaller than or equal to N, to produce transformed symbols. The method also includes sending a signal representing the transformed symbols to a plurality of transmitters for transmission of a signal representing the transformed symbols to a plurality of receivers. A signal representing the unitary matrix is sent to a second compute device for transmission of the unitary matrix to the receivers for recovery of the plurality of symbols at the plurality of receivers.
FILED	Monday, July 01, 2019
APPL NO	16/459262
ART UNIT	2415 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/0413 (20130101) H04B 7/0634 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10834346 — Programmable digital TDI EO/IR scanning focal plane array with multiple selectable TDI sub-banks

US 10834346	Botts et al.
FUNDED BY
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	Steven Botts (Santa Barbara, California); Bryan W. Kean (Denver, Colorado); Richard J. Peralta (Santa Barbara, California); John L. Vampola (Goleta, California); Micky R. Harris (Lompoc, California)
ABSTRACT	A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region.
FILED	Thursday, May 30, 2019
APPL NO	16/426863
ART UNIT	2488 — Recording and Compression
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/332 (20130101) H04N 5/378 (20130101) H04N 5/3592 (20130101) H04N 5/36961 (20180801) Original (OR) Class H04N 5/37213 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 10, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201110.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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