FedInvent™ Patents
Patent Details for Tuesday, November 24, 2020
This page was updated on Monday, March 27, 2023 at 06:14 AM GMT
Department of Health and Human Services (HHS)
| US 10842373 | Fink et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Wolfgang Fink (Tucson, Arizona); Mark Tarbell (Tucson, Arizona) |
| ABSTRACT | Various examples of methods, systems and devices are provided for ophthalmic examination. In one example, a handheld system includes an optical imaging assembly coupled to a user device that includes a camera aligned with optics of the optical imaging assembly. The user device can obtain ocular imaging data of at least a portion of an eye via the optics of the optical imaging assembly and provide ophthalmic evaluation results based at least in part upon the ocular imaging data. In another example, a method includes receiving ocular imaging data of at least a portion of an eye; analyzing the ocular imaging data to determine at least one ophthalmic characteristic of the eye; and determining a condition based at least in part upon the at least one ophthalmic characteristic. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/571701 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) Original (OR) Class A61B 3/14 (20130101) A61B 3/0033 (20130101) A61B 3/0041 (20130101) A61B 3/135 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842382 | Feldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Martin Feldman (Baton Rouge, Louisiana); Dooyoung Hah (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Martin Feldman (Baton Rouge, Louisiana); Dooyoung Hah (Baton Rouge, Louisiana) |
| ABSTRACT | A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106722 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/002 (20130101) A61B 1/06 (20130101) A61B 1/0011 (20130101) A61B 1/0661 (20130101) A61B 5/0075 (20130101) Original (OR) Class A61B 5/0084 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/0205 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842401 | Trayanova et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Sohail Zahid (Baltimore, Maryland); Patrick Boyle (Baltimore, Maryland) |
| ABSTRACT | A computer-implemented method for non-invasively identifying ablation locations in atrial tissue, can include: receiving three-dimensional imaging data representing atrial tissue of a left atrial flutter (LAFL) subject; generating a subject-specific model of the at least one of the atrial tissue from the three-dimensional imaging data; estimating tissue fiber orientations in the atrial tissue; assigning the estimated tissue fiber orientations to the subject-specific model of the atrial tissue; conducting simulations of LAFL using the subject-specific model to identify regions of slow conduction of a propagating wave within an atrial tissue region of the atrial tissue; a critical isthmus of a rotational wavefront within the atrial tissue region; or a region based on a minimum cut in a flow network; and identifying at least one ablation location in the atrial tissue region based on the identified regions of slow conduction, the critical isthmus, or the minimum cut. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/573292 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0044 (20130101) A61B 5/046 (20130101) Original (OR) Class A61B 5/0059 (20130101) A61B 5/0073 (20130101) A61B 5/0082 (20130101) A61B 18/1492 (20130101) A61B 2018/00357 (20130101) A61B 2018/00577 (20130101) A61B 2018/00839 (20130101) A61B 2576/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842440 | Shusterman |
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| FUNDED BY |
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| APPLICANT(S) | Vladimir Shusterman (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladimir Shusterman (Pittsburgh, Pennsylvania) |
| ABSTRACT | A wireless monitoring system that provides reliable wireless data transmission during patient table (bed) movement. The system makes use of at least one wireless antenna linked to the patient table to provide substantially continuous, unobstructed communication regardless of the patient table's position and the movement of medical personnel around the table. The system also utilizes adaptive filtering of electromagnetic interference, signal conditioning, and detection of cardiac-activity waveforms, providing means for adjusting signal-processing parameters to the specific features of electromagnetic interference and cardiac waveforms. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/442705 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0006 (20130101) A61B 5/021 (20130101) A61B 5/0024 (20130101) A61B 5/053 (20130101) A61B 5/055 (20130101) A61B 5/0205 (20130101) A61B 5/0263 (20130101) A61B 5/0402 (20130101) A61B 5/0476 (20130101) A61B 5/0488 (20130101) A61B 5/0555 (20130101) A61B 5/7203 (20130101) Original (OR) Class A61B 5/7221 (20130101) A61B 5/7225 (20130101) A61B 5/7282 (20130101) A61B 5/14551 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842455 | Boone et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John M. Boone (Folsom, California); Thomas R. Yellen-Nelson (Del Mar, California) |
| ABSTRACT | A device and methods for performing a simulated CT biopsy on a region of interest on a patient. The device comprises a gantry (22) configured to mount an x-ray emitter (24) and CT detector (26) on opposing sides of the gantry, a motor (28) rotatably coupled to the gantry such that the gantry rotates horizontally about the region of interest, and a rotation of source high resolution x-ray detector (172) positioned adjacent the CT detector in between the CT detector and and detector the x-ray emitter. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717886 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/03 (20130101) A61B 6/12 (20130101) A61B 6/037 (20130101) A61B 6/405 (20130101) A61B 6/0435 (20130101) A61B 6/482 (20130101) Original (OR) Class A61B 6/502 (20130101) A61B 6/584 (20130101) A61B 6/4028 (20130101) A61B 6/4417 (20130101) A61B 6/4423 (20130101) A61B 6/5235 (20130101) A61B 8/0825 (20130101) A61B 8/4416 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842504 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The United Dtates of America, as represented by the Secretary of the Navy (Washington, District of Columbia); The United States of America, as represented by the Secretary of Defense (Washington, District of Columbia) |
| INVENTOR(S) | Chad Gordon (Cockeysville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 16/561984 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842631 | Karimov et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Jamshid Karimov (Cleveland Heights, Ohio); Marc Gillinov (Cleveland, Ohio); Kiyotaka Fukamachi (Mayfield Heights, Ohio) |
| ABSTRACT | Systems and methods for de-airing a cardiac chamber during cardiac surgery are provided. A catheter-based inflatable device is inserted adjacent a target area of the heart, and the frequency of inflation and deflation of the inflatable device is controlled via a remote controller to change the shape of the cardiac chamber to dislodge air bubbles from their deposition site in the cardiac chamber. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903737 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12136 (20130101) A61B 2017/0023 (20130101) A61B 2017/00084 (20130101) A61B 2017/00132 (20130101) A61B 2017/00154 (20130101) A61B 2017/00212 (20130101) A61B 2017/00243 (20130101) A61B 2017/00292 (20130101) A61B 2017/00557 (20130101) A61B 2017/00778 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2481 (20130101) Original (OR) Class A61F 2002/2484 (20130101) A61F 2250/0003 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) A61M 2025/1072 (20130101) A61M 2025/1088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842693 | Duerstock et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley S. Duerstock (West Lafayette, Indiana); Jeffrey Ackerman (Arvada, Colorado) |
| ABSTRACT | The present disclosure illustrates a motorized mount with a plurality of degrees of freedom coupled to a seating system. The motorized mount assembly can include an attachment assembly configured to attach to a seating assembly. A vertical control assembly can be connected to the attachment assembly with an arm having a first end attached to vertical control assembly by a first hinge. A mounting assembly can be attached to a second end of the arm. The mounting assembly can configured to receive a personal computing device. A linear actuator may be attached to the vertical control assembly to raise and lower the arm and mounting assembly. A first motor can be configured to attach to the arm. A second motor can be configured to attach between the arm and the mounting assembly. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 16/007638 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Chairs; Sofas; Beds A47C 7/62 (20130101) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/04 (20130101) A61G 5/08 (20130101) A61G 5/1094 (20161101) Original (OR) Class A61G 2203/16 (20130101) A61G 2203/20 (20130101) Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for B60N 3/002 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/18 (20130101) F16M 11/38 (20130101) F16M 13/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842743 | Roth et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Michael D. Roth (Los Angeles, California); Airi Harui (Los Angeles, California) |
| ABSTRACT | Hyaluronic acid-based hydrogels, solutions for preparing such, and methods pertaining thereunto are disclosed with properties that include self-resorption, extended release of biologically active agents, and/or decreased degradation, denaturation, and/or functional inactivation of biologically active agents. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 16/091604 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/0019 (20130101) A61K 38/47 (20130101) A61K 45/06 (20130101) A61K 47/14 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/256 (20130101) A61L 2300/426 (20130101) A61L 2400/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/2818 (20130101) C07K 16/2878 (20130101) C07K 16/2896 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842753 | Vegas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Arturo J. Vegas (Belmont, Massachusetts); Minglin Ma (Ithaca, New York); Kaitlin M. Bratlie (Ames, Iowa); Daniel G. Anderson (Framingham, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 16/408899 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5036 (20130101) Original (OR) Class A61K 9/5161 (20130101) A61K 35/39 (20130101) A61K 45/06 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842775 | Burnett et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); Levo Therapeutics, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); LEVO THERAPEUTICS, INC. (Skokie, Illinois) |
| INVENTOR(S) | Lisa Cole Burnett (Chicago, Illinois); Dieter Egli (New York, New York); Rudolph L. Leibel (New York, New York); Sara Cotter (New York, New York) |
| ABSTRACT | The present invention relates to methods for regulating prohormone convertase (PC1) and compounds and treatments which increase PC1 levels, for treating Prader-Willi Syndrome (PWS). |
| FILED | Friday, June 02, 2017 |
| APPL NO | 16/306233 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 31/366 (20130101) Original (OR) Class A61K 31/403 (20130101) A61K 31/403 (20130101) A61K 31/426 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/522 (20130101) A61K 31/522 (20130101) A61K 31/4015 (20130101) A61K 31/4015 (20130101) A61K 31/4035 (20130101) A61K 31/4035 (20130101) A61K 31/4162 (20130101) A61K 31/4162 (20130101) A61K 31/4375 (20130101) A61K 31/4375 (20130101) A61K 31/5513 (20130101) A61K 31/5513 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/095 (20190101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842783 | Lamichhane |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Gyanu Lamichhane (Towson, Maryland) |
| ABSTRACT | Described are methods of treating or preventing a bacterial infection by administering an antibacterial agent comprising a β-lactamase inhibitor and one or more carbapenem to a subject. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560006 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842785 | Bieberich et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Charles J. Bieberich (Brookeville, Maryland); Xiang Li (Baltimore, Maryland); Tejashree Joglekar (Savage, Maryland) |
| ABSTRACT | The present invention provides for a method of treating cancer and/or reducing proliferation of cancer cells, the method comprising administering to a subject in need of such treatment a composition comprising a PIM kinase inhibitor that exhibits changes of mRNA splicing in combination with a compound that modulates/inhibits activity of an RNA splicing factor protein. Further, changes in splicing of mRNAs and phosphorylation of RNA splicing factors can be used as biomarkers for patient responsiveness to anti-PIM treatment and also suggest effective combinatorial therapies, including synergistic combination. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598536 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/351 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/426 (20130101) A61K 31/437 (20130101) A61K 31/453 (20130101) A61K 31/453 (20130101) A61K 31/454 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 31/4412 (20130101) A61K 31/5025 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842791 | Whitehead et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Christopher Emil Whitehead (Ann Arbor, Michigan); Judith S. Leopold (Ann Arbor, Michigan) |
| ABSTRACT | This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207998 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 403/14 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842807 | Yano et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hiroko Yano (St. Louis, Missouri); Albert Kim (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Hiroko Yano (St. Louis, Missouri); Albert Kim (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides a method of treating a neurodegenerative disorder, the method comprising administering a DNA methyltransferase inhibitor. |
| FILED | Tuesday, June 13, 2017 |
| APPL NO | 16/309796 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/7068 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10842816 — Compositions and methods for isolating and enriching IgM-producing cells and uses thereof
| US 10842816 | Zhong et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Xuemei Zhong (Sharon, Massachusetts); Joyce Wong (Chestnut Hill, Massachusetts) |
| ABSTRACT | The technology described herein relates, at least in part, to compositions comprising and methods for isolating and enriching natural IgM-producing phagocytic B (NIMPAB) cells and methods of producing IgM antibodies using such cells, as well as uses of the antibodies produced by the methods for the prevention and treatment of diseases wherein immunotherapy with such natural IgM antibodies and their derivatives can be useful. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/102905 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 47/24 (20130101) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/00 (20130101) C07K 16/30 (20130101) C07K 2317/52 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) C12N 5/0635 (20130101) C12N 5/0693 (20130101) C12N 2529/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842828 | Bishai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | William R. Bishai (Baltimore, Maryland); Ruchi Jain Dey (Baltimore, Maryland); Bappaditya Dey (Baltimore, Maryland); Laurene Cheung (Baltimore, Maryland) |
| ABSTRACT | Described herein are methods of treating or preventing cancer in a subject comprising administering to the subject an effective amount of a bacteria comprising and expression vector encoding a di-adenylate cyclase enzyme. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/147916 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 39/04 (20130101) A61K 48/00 (20130101) A61K 2039/522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842832 | Bushman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Frederic Bushman (Rose Valley, Pennsylvania); Gary Wu (Ardmore, Pennsylvania); James Lewis (Moorestown, Pennsylvania); Mark Goulian (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention provides for the treatment of hyperammonemia, Clostridium difficile colitis, hepatic encephalopathy associated with cirrhosis, and inflammatory bowel disease. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/114961 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/48 (20130101) A61K 31/77 (20130101) A61K 31/77 (20130101) A61K 31/7036 (20130101) A61K 31/7036 (20130101) A61K 35/74 (20130101) A61K 35/74 (20130101) A61K 35/742 (20130101) A61K 35/742 (20130101) A61K 35/744 (20130101) A61K 35/744 (20130101) A61K 35/745 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) Original (OR) Class A61K 35/747 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) Y02A 50/475 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842835 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Bertram Jacobs (Tempe, Arizona); Heather Koehler (Phoenix, Arizona); William Arndt (Albuquerque, New Mexico); Karen Kibler (Scottsdale, Arizona); Kelly Trainor (Prescott, Arizona); Chandra Mitnik (Tempe, Arizona); Jeffrey Langland (Chandler, Arizona) |
| ABSTRACT | Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL. |
| FILED | Thursday, May 25, 2017 |
| APPL NO | 16/304564 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/768 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/24121 (20130101) C12N 2710/24122 (20130101) C12N 2710/24132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842843 | Budd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Ralph C. Budd (Hinesburg, Vermont); Cheryl Collins (Burlington, Vermont) |
| ABSTRACT | Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/572698 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 35/15 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/0225 (20130101) A61K 2039/6006 (20130101) Technologies for Adaptation to Climate Change Y02A 50/48 (20180101) Y02A 50/401 (20180101) Y02A 50/478 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842845 | Mendelowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | David Mendelowitz (Vienna, Virginia); Vivek Jain (McLean, Virginia); Heather Jameson (Arlington, Virginia); Jay Shawn Kimbro (Stevensville, Maryland) |
| ABSTRACT | The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/184091 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 38/095 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842849 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 14/002033 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 9/0085 (20130101) A61K 9/5169 (20130101) A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 35/30 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/30 (20130101) A61K 38/1703 (20130101) A61K 38/1709 (20130101) A61K 38/1738 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 49/0056 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 2501/105 (20130101) C12N 2502/08 (20130101) C12N 2502/081 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/5073 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842852 | Prochiantz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Centre National de la Recherche Scientifique (Paris, France); Ecole Normale Superieure (Paris, France) |
| ASSIGNEE(S) | Centre National de la Recherche Scientifique (Paris, France); Ecole Normale Superieure (Paris, France) |
| INVENTOR(S) | Alain Prochiantz (Paris, France); Ariel Di Nardo (Palaiseau, France); Marine Beurdeley (Paris, France); Takao Hensch (Newton, Massachusetts) |
| ABSTRACT | The disclosure provides a method of delivering a polypeptide molecule to an Otx2 target cell, including contacting the target cell with a chimeric polypeptide having (i) a targeting peptide consisting of SEQ ID NO: 2 and (ii) the polypeptide molecule. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/280502 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 35/12 (20130101) A61K 35/30 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 47/62 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/383 (20130101) A61L 27/3604 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 27/02 (20180101) A61P 43/00 (20180101) Peptides C07K 14/47 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0602 (20130101) C12N 5/0618 (20130101) C12N 5/0619 (20130101) C12N 5/0621 (20130101) C12N 9/16 (20130101) C12N 15/85 (20130101) C12N 15/907 (20130101) C12N 2501/40 (20130101) C12N 2501/50 (20130101) C12N 2501/58 (20130101) C12N 2502/085 (20130101) C12N 2506/08 (20130101) C12N 2830/008 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Enzymes C12Y 301/03001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5044 (20130101) G01N 33/5058 (20130101) G01N 33/57496 (20130101) G01N 2500/10 (20130101) G01N 2800/164 (20130101) G01N 2800/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842857 | Lyerly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding a HER2 polypeptide or a truncation, deletion or substitution mutant thereof. Methods of using the vaccine including the polynucleotide encoding the HER2 polypeptide to treat a cancer or precancer are also provided. The vaccines may be administered with a cancer therapeutic or prevention agent or a checkpoint inhibitor immunomodulatory agent. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045248 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 39/0011 (20130101) A61K 39/0011 (20130101) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/53 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842859 | Bucala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut); GlaxoSmithKline Biologicals SA (Rixensart, Belgium) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); GlaxoSmithKline Biologicals SA (Rixensart, Belgium) |
| INVENTOR(S) | Richard Bucala (New Haven, Connecticut); Andrew Geall (Cambridge, Massachusetts) |
| ABSTRACT | This invention relates to compositions (e.g. vaccine compositions) which can be used to provide a subject with protective immunity against a parasite infection. The compositions comprise: (i) an immunologically effective amount of a nucleic acid (e.g. a nucleic acid-based vaccine) comprising a sequence which encodes a parasite macrophage migration inhibitory factor (MIF) antigen; (ii) a parasite MIF antigen; or (iii) an antibody which specifically binds to a parasite MIF antigen. The compositions may be used to treat infections and diseases caused by parasitic protozoans, such as a Plasmodium parasite, or parasitic helminths. |
| FILED | Tuesday, March 24, 2015 |
| APPL NO | 15/128851 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 9/127 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/44 (20130101) C07K 14/445 (20130101) C07K 16/24 (20130101) C07K 16/205 (20130101) Technologies for Adaptation to Climate Change Y02A 50/41 (20180101) Y02A 50/412 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842862 | Morrison |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Trudy G Morrison (Northborough, Massachusetts) |
| ABSTRACT | The invention provides methods for using virus-like particle (VLP) vaccines containing a stabilized pre-fusion respiratory syncytial virus (RSV) F protein to stimulate RSV neutralizing antibodies in pre-immune subjects. In one embodiment, the invention provides a method for immunizing a mammalian subject in need of immunizing against Respiratory Syncytial virus (RSV) infection, comprising, a) providing i) a pre-immune mammalian subject containing RSV neutralizing antibodies, ii) a first composition comprising recombinant chimeric Newcastle disease virus-like particles (ND VLPs), that contain a chimeric protein comprising, in operable combination, 1) stabilized pre-fusion RSV F protein ectodomain, 2) transmembrane (TM) domain of NDV F protein, and 3) cytoplasmic (CT) domain of NDV F protein, and b) administering an immunologically effective amount of the first composition to the pre-immune subject to produce an immunized subject that comprises an increase in the level of the RSV neutralizing antibodies compared to the level of RSV neutralizing antibodies in the pre-immune subject. In one embodiment, the level of the RSV neutralizing antibodies in the pre-immune subject does not prevent RSV infection of the pre-immune subject. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 16/339219 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/17 (20130101) Original (OR) Class A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18122 (20130101) C12N 2760/18134 (20130101) C12N 2760/18171 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842864 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Don J. Diamond (Glendora, California); Felix Wussow (Duarte, California) |
| ABSTRACT | In one embodiment, an expression system for expressing a UL128 complex is provided herein. The expression system may include a bacterial artificial chromosome (BAC) construct, wherein the BAC construct comprises a viral vector inserted with a set of DNA sequences that encode a UL128 complex. In another embodiment, a vaccine composition for preventing HCMV infection is provided. The vaccine composition may include a viral or bacterial vector capable of expressing a UL128 complex and a pharmaceutically acceptable carrier, adjuvant, additive or combination thereof or additional vector expressing a protein adjuvant. The viral vector may be an MVA and the UL128 complex includes five HCMV proteins or antigenic fragments thereof: UL128, UL130, UL131A, gL, and gH. In some embodiments, the viral vector is further inserted with one or more additional DNA sequences that encode one or more additional HCMVHCMV proteins or antigenic fragments thereof such as pp65, gB or both, or such as gM/gN or gO. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538668 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) C12N 2710/24143 (20130101) C12N 2799/023 (20130101) C12N 2800/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842891 | Hooker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jacob M. Hooker (Charlestown, Massachusetts); Changning Wang (Acton, Massachusetts); Frederick Albert Schroeder (Baltimore, Massachusetts) |
| ABSTRACT | Disclosed herein are histone deacetylase imaging agents for positron emission tomography and related imaging methods using the histone deacetylase imaging agents. The histone deacetylase imaging agents may be a compound of formula (I): wherein R1 is a moiety including a positron emitter; R2 represents hydrogen, or substituted or unsubstituted alkyl, or substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and n is an integer selected from 0 or 1. In one version of the compound of formula (I), R1 is a moiety including an adamantyl group. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/213358 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 259/06 (20130101) C07C 259/08 (20130101) C07C 275/34 (20130101) C07C 311/16 (20130101) C07C 311/21 (20130101) C07C 2601/14 (20170501) C07C 2602/10 (20170501) C07C 2603/74 (20170501) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/14 (20130101) C07D 235/08 (20130101) C07D 267/16 (20130101) C07D 281/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10842893 — Multifunctional chelators, complexes, and compositions thereof, and methods of using same
| US 10842893 | Chong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hyun-Soon Chong (Chicago, Illinois) |
| ASSIGNEE(S) | ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois) |
| INVENTOR(S) | Hyun-Soon Chong (Chicago, Illinois) |
| ABSTRACT | Multifunctional chelators, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/562577 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0474 (20130101) A61K 51/0482 (20130101) Original (OR) Class Heterocyclic Compounds C07D 255/02 (20130101) C07D 257/02 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842920 | Aho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Johnathon M. Aho (Rochester, Minnesota); Raaj K. Ruparel (Rochester, Minnesota); Phillip G. Rowse (Rochester, Minnesota); Cornelius A. Thiels (Rochester, Minnesota); Twinkle Kumar Pandian (Rochester, Minnesota); Nimesh D. Naik (Rochester, Minnesota) |
| ABSTRACT | This document provides systems and methods that can improve the efficacy of tube and needle thoracostomy. For example, this document provides devices and methods for confirming the proper placement of a chest tube or needle within the pleural space to relieve a pneumothorax or tension pneumothoax. |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 15/534126 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0088 (20130101) Original (OR) Class A61M 2205/6081 (20130101) A61M 2210/101 (20130101) A61M 2230/432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842934 | El-Khatib et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Firas H. El-Khatib (Allston, Massachusetts); Edward R. Damiano (Acton, Massachusetts); Steven J. Russell (Lincoln, Massachusetts) |
| ABSTRACT | A glucose control system employs adaptation of a glucose target (set-point) control variable in controlling delivery of insulin to a subject to maintain euglycemia. The glucose target adapts based on trends in actual glucose level (e.g., measured blood glucose in the subject), and/or computed doses of a counter-regulatory agent such as glucagon. An adaptation region with upper and lower bounds for the glucose target may be imposed. Generally the disclosed techniques can provide for robust and safe glucose level control. Adaptation may be based on computed doses of a counter-regulatory agent whether or not such agent is actually delivered to the subject, and may be used for example to adjust operation in a bihormonal system during periods in which the counter-regulatory agent is not available for delivery. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/748333 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4839 (20130101) A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2005/14208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843100 | Khan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Abdul Wahid Khan (Murrysville, Pennsylvania); Dennis Brian Hubbard (Lancaster, Massachusetts) |
| ABSTRACT | A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/603699 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 1/18 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843996 | Ortlund et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Eric Ortlund (Decatur, Georgia); Suzanne Mays (Marietta, Georgia); Nathan Jui (Decatur, Georgia); Autumn Flynn (Decatur, Georgia); Michael Dugan (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to modulators of liver receptor homologue 1 (LRH-1) and methods of managing disease and conditions related thereto. In certain embodiments, modulators are derivatives of hexahydropentalene. In certain embodiments, this disclosure relates to methods of treating or preventing cancer, diabetes, or cardiovascular disease by administering an effective amount of a hexahydropentalene derivative disclosed herein. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 16/495092 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 35/50 (20130101) C07C 39/23 (20130101) C07C 43/23 (20130101) C07C 49/83 (20130101) C07C 49/683 (20130101) C07C 59/54 (20130101) Original (OR) Class C07C 215/70 (20130101) C07C 255/47 (20130101) C07C 271/34 (20130101) C07C 307/02 (20130101) C07C 309/66 (20130101) C07C 2602/22 (20170501) Heterocyclic Compounds C07D 249/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) C07F 9/572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844021 | Crew et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| INVENTOR(S) | Andrew P. Crew (Guilford, Connecticut); Lawrence B. Snyder (Killingworth, Connecticut); Jing Wang (Milford, Connecticut) |
| ABSTRACT | The present disclosure relates to bifunctional compounds, which find utility to degrade and (inhibit) Androgen Receptor. In particular, the present disclosure is directed to compounds, which contain on one end a cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds Androgen Receptor, such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present disclosure exhibits a broad range of pharmacological activities associated with compounds according to the present disclosure, consistent with the degradation/inhibition of Androgen Receptor. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577901 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/166 (20130101) A61K 31/277 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 209/48 (20130101) C07D 211/76 (20130101) C07D 213/72 (20130101) C07D 221/20 (20130101) C07D 231/12 (20130101) C07D 233/42 (20130101) Original (OR) Class C07D 237/08 (20130101) C07D 239/24 (20130101) C07D 241/04 (20130101) C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844023 | Dorn, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Gerald W. Dorn, II (St. Louis, Missouri); James Janetka (St. Louis, Missouri) |
| ABSTRACT | Compositions comprising small molecule mitofusin agonists are described. The mitofusin modulating agents are useful for treating diseases or disorders associated with a mitochondria-associated disease, disorder, or condition such as diseases or disorders associated with mitofusin 1 (Mfn1) and/or mitofusin 2 (Mfn2), or mitochondrial dysfunction. Methods of treatment, pharmaceutical formulations, and screening methods for identifying compounds that regulate mitochondrial function are also described. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/152172 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 249/12 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844025 | Pierce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Joshua G. Pierce (Raleigh, North Carolina); Jonathan J. Mills (Raleigh, North Carolina) |
| ABSTRACT | Provided herein are oxazolidinone derivatives that can exhibit anti-microbial activity and/or activity as biofilm modulating agents (e.g., activity as biofilm inhibitors and/or activity as biofilm dispersal agents). The compounds can exhibit potent activity anti-microbial activity (e.g., potent activity against Gram-positive positive bacteria including methicillin-resistant Staphylococcus aureus). The compounds can exhibit potent activity against biofilms. In some cases, the compounds can exhibit both anti-microbial activity and biofilm modulation properties. |
| FILED | Tuesday, August 22, 2017 |
| APPL NO | 16/327478 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/76 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 31/08 (20130101) A61L 31/16 (20130101) A61L 2300/204 (20130101) A61L 2300/404 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 263/40 (20130101) Original (OR) Class C07D 263/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844026 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biohaven Pharmaceutical Holding Company Ltd. (New Haven, Connecticut); Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Biohaven Pharmaceutical Holding Company Ltd. (New Haven, Connecticut); Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Garry Robert Smith (Royersford, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Mark McDonnell (Lansdale, Pennsylvania); Suzie Chen (Highland Park, New Jersey); Matthew D. Vera (Collegeville, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Jeffrey Claude Pelletier (Lafayette Hill, Pennsylvania); Venkata N. Velvadapu (Philadelphia, Pennsylvania); Jay Edward Wrobel (Lawrenceville, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/748354 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 277/82 (20130101) Original (OR) Class C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844028 | Mahon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kerry Peter Mahon (Cambridge, Massachusetts); Kevin Thomas Love (Boston, Massachusetts); Christopher G. Levins (Flemington, New Jersey); Kathryn Ann Whitehead (Pittsburgh, Pennsylvania); Robert S. Langer (Newton, Massachusetts); Daniel Griffith Anderson (Framingham, Massachusetts) |
| ABSTRACT | Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/208295 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 9/1271 (20130101) A61K 9/5123 (20130101) A61K 31/7088 (20130101) A61K 38/02 (20130101) A61K 47/16 (20130101) A61K 47/54 (20170801) A61K 47/545 (20170801) A61K 48/0025 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2531/0252 (20130101) B01J 2531/845 (20130101) Acyclic or Carbocyclic Compounds C07C 215/14 (20130101) C07C 217/08 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 15/111 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844044 | Alvarado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Joseph R. Alvarado (Nashville, Tennessee); Shaun R. Stauffer (Brentwood, Tennessee); Rocco D. Gogliotti (Kingston Springs, Tennessee); Changho Han (Nashville, Tennessee); Kenneth M. Meyers (Nashville, Tennessee); Jianhua Tian (Nashville, Tennessee); Jonathan D. Macdonald (Nashville, Tennessee); Stephen W. Fesik (Nashville, Tennessee); Taekyu Lee (Brentwood, Tennessee) |
| ABSTRACT | Described are imino-azacycle-benzamide compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441854 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 233/88 (20130101) C07D 401/06 (20130101) C07D 401/10 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 405/10 (20130101) C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844052 | Lam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kit S. Lam (Davis, California); Ruiwu Liu (Sacramento, California); Tsung-Chieh Shih (Davis, California) |
| ABSTRACT | The present invention provides benzamidazole compounds and methods of using the compounds as galectin-1 inhibitors. |
| FILED | Tuesday, April 04, 2017 |
| APPL NO | 16/091098 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 235/14 (20130101) C07D 235/18 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 403/12 (20130101) C07D 409/14 (20130101) C07D 413/10 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/18 (20130101) Compositions of Macromolecular Compounds C08L 79/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844077 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Sara Jean Buhrlage (Somerville, Massachusetts); Steven P. Treon (Jamaica Plain, Massachusetts); Hwan Geun Choi (Chestnut Hill, Massachusetts); Yuan Xiong (Brookline, Massachusetts); Guang Yang (Natick, Massachusetts) |
| ABSTRACT | The present disclosure provides thiazolyl-containing compounds of Formula (I), (II), or (III). The compounds described herein may be able to inhibit protein kinases (e.g. Src family kinases (e.g. hemopoietic cell kinase (HCK)), Bruton's tyrosine kinase (BTK)) and may be useful in treating and/or preventing proliferative diseases (e.g. myelodysplasia, leukemia, lymphoma, (e.g. Waldenström's macroglobulinemia)) and in inducing apoptosis in a cell (e.g. malignant blood cell). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/672198 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Heterocyclic Compounds C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844089 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
| INVENTOR(S) | Shunlin Ren (Richmond, Virginia); William M. Pandak (Richmond, Virginia) |
| ABSTRACT | The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided. |
| FILED | Monday, October 08, 2018 |
| APPL NO | 16/154007 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Steroids C07J 9/00 (20130101) C07J 31/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844093 | Krishna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REALTA HOLDINGS, LLC (Norfolk, Virginia) |
| ASSIGNEE(S) | REALTA HOLDINGS, LLC (Norfolk, Virginia) |
| INVENTOR(S) | Neel K. Krishna (Norfolk, Virginia); Kenji Cunnion (Norfolk, Virginia) |
| ABSTRACT | The present invention provides peptide compounds that regulate the complement system and methods of using these compounds. The invention is an isolated, purified peptide of 30 amino acids derived from human astrovirus protein, called CP1. The invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of CP1 having, for example, internal peptide deletions and substitutions, deletions and substitutions at the N-terminus and C-terminus, and that are able to regulate complement activation. The invention further provides pharmaceutical compositions of therapeutically effective amounts of the peptide compounds and a pharmaceutically acceptable carrier, diluent, or excipient for treating a disease or condition associated with complement-mediated tissue damage. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/534200 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/03 (20130101) A61K 38/10 (20130101) A61K 38/162 (20130101) A61K 38/1725 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/005 (20130101) C07K 14/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/12022 (20130101) C12N 2770/12033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844095 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York) |
| ASSIGNEE(S) | INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York) |
| INVENTOR(S) | Christopher L. Parks (New York, New York); Ivo Lorenz (New York, New York); Sanjay K. Phogat (New York, New York); Timothy J. Zamb (New York, New York) |
| ABSTRACT | The present relation relates to recombinant vesicular stomatitis virus for use as prophylactic and therapeutic vaccines for infectious diseases of AIDS. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/267058 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16051 (20130101) C12N 2740/16134 (20130101) C12N 2760/20234 (20130101) C12N 2760/20243 (20130101) C12N 2760/20251 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 2333/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844105 | Silva Manzano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Daniel Adriano Silva Manzano (Seattle, Washington); Shawn Yu (Seattle, Washington); Umut Ulge (Seattle, Washington); David Baker (Seattle, Washington); Kenan Christopher Garcia (Stanford, California); Jamie Spangler (Stanford, California); Carl Walkey (Seattle, Washington) |
| ABSTRACT | De novo designed polypeptides that bind to IL-2 receptor β |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909185 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 14/5437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844106 | Cochran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jennifer R. Cochran (Stanford, California); Douglas S. Jones (Cambridge, Massachusetts); Mihalis S. Kariolis (Stanford, California); Ping-Chuan Tsai (Fremont, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Jennifer R. Cochran (Stanford, California); Douglas S. Jones (Cambridge, Massachusetts); Mihalis S. Kariolis (Stanford, California); Ping-Chuan Tsai (Fremont, California) |
| ABSTRACT | The present disclosure presents a general approach to engineering existing protein-protein interactions through domain addition and evolution. The disclosure teaches the creation of novel fusion proteins that include knottin peptides where a portion of the knottin peptide is replaced with a sequence that has been created for binding to a particular target. Such fusion proteins can also be bispecific or multi specific in that they can bind to and/or inhibit two or more receptors or receptor ligands. Knottins may be fused with an existing ligand (or receptor) as a general platform for increasing the affinity of a ligand-receptor interaction or for creating a multi specific protein. In addition, the fusion proteins may comprise a knottin peptide fused to another protein where the other protein facilitates proper expression and folding of the knottin. |
| FILED | Monday, November 07, 2011 |
| APPL NO | 13/883216 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/71 (20130101) C07K 14/81 (20130101) C07K 14/475 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/4702 (20130101) C07K 14/8121 (20130101) C07K 14/43518 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844118 | Winau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Florian E. Winau (Boston, Massachusetts); Ji Hyung Kim (Brookline, Massachusetts) |
| ABSTRACT | The methods, compositions, and assays described herein are based, in part, on the discovery that CD1a mediates inflammation related to certain conditions such as urushiol exposure, psoriasis and other inflammatory skin diseases. One aspect provided herein relates to a method for treating or preventing an inflammatory skin disease, the method comprising: administering a therapeutically effective amount of an inhibitor of CD 1a to a subject having an inflammatory skin disease, thereby treating or preventing the inflammatory skin diseases. |
| FILED | Wednesday, September 17, 2014 |
| APPL NO | 15/023283 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 31/04 (20130101) A61K 31/05 (20130101) A61K 31/437 (20130101) A61K 31/713 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/5047 (20130101) G01N 2333/70539 (20130101) G01N 2800/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844128 | Orentas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Seattle, Washington); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing CD123 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/578063 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2740/15041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844352 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees Of The University of Pennsyivania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Xiaowei Xu (Monmouth Junction, New Jersey); Ruifeng Yang (Philadelphia, Pennsylvania) |
| ABSTRACT | Compositions and methods for generating melanocytes through direct reprogramming are disclosed. Also disclosed are methods of use of such compositions for the treatment of vitiligo and other hypopigmentation disorders. In accordance with the present invention, a method for producing melanocytes suitable for use in human patients is provided. An exemplary method comprises providing cells capable of transdifferentiation into melanocytes, culturing said cells in a chemically defined culture medium, introducing at least two of microphthalmia-associated transcription factor (MITF), SRY-related HMG-box (SOX10) transcription factor and paired box-3 (PAX-3) transcription factor and paired box-3 (PAX-3) transcription factor, or nucleic acids encoding said transcription factors into said cells, wherein expression of said factors induces the cells to transdifferentiae into melanocytes expressing melanocyte markers TYR, DCT, S-100 and Melan-A. |
| FILED | Wednesday, November 18, 2015 |
| APPL NO | 15/527334 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/36 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/60 (20130101) A61L 27/3813 (20130101) A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 27/3895 (20130101) A61L 2300/64 (20130101) A61L 2430/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0626 (20130101) Original (OR) Class C12N 2501/01 (20130101) C12N 2501/60 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/365 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844353 | Ward et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GPB SCIENTIFIC, LLC (Richmond, Virginia); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | GPB Scientific, Inc. (Richmond, Virginia); The Trustees of Princeton University (Princeton, New Jersey); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Anthony Ward (Rancho Santa Fe, California); Roberto Campos-Gonzalez (Carlsbad, California); Alison Skelley (Riverside, California); Khushroo Gandhi (Palo Alto, California); Curt Civin (Baltimore, Maryland); James C. Sturm (Princeton, New Jersey); Michael Grisham (Richmond, Virginia) |
| ABSTRACT | The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/108365 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2531/00 (20130101) C12N 2533/54 (20130101) C12N 2533/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844362 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard (Cambridge, Massachusetts) |
| INVENTOR(S) | Min Dong (Weatogue, Connecticut); Lisheng Peng (Guangzhou, China PRC); Pål Erik Gustav Stenmark (Järfälla, Sweden); Ronnie Per Arne Berntsson (Umeå, Sweden) |
| ABSTRACT | Disclosed herein are botulinum neurotoxin (BoNT) polypeptides with a modified receptor binding domain of Clostridial botulinum serotype B (B-Hc), comprising one or more substitution mutations corresponding to substitution mutations in serotype B, strain 1, V1118M; Y1183M; E1191M; E1191I; E1191Q; E1191T; S1199Y; S1199F; S1199L; S1201V; or combinations thereof. Specific combination mutations include E1191M and S1199L, E1191M and S1199Y, E1191M and S1199F, E1191Q and S1199L, E1191Q and S1199Y, or E1191Q and S1199F. Other substitution mutations are also disclosed. Isolated modified receptor binding domains, chimeric molecules, pharmaceutical compositions, and methods of using the same are also disclosed. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/252083 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/24069 (20130101) Technologies for Adaptation to Climate Change Y02A 50/469 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844377 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Julia Alterman (Worcester, Massachusetts); Matthew Hassler (Worcester, Massachusetts) |
| ABSTRACT | Provided are compositions and methods comprising two-tailed siRNAs (tt-siRNAs) that exhibit unprecedented cellular uptake and silencing. Also provided are methods of treating neurological and other diseases with the two-tailed siRNAs of the invention. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/015440 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/314 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/343 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844387 | Kochenderfer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683477 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844388 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nature Technology Corporation (Lincoln, Nebraska) |
| ASSIGNEE(S) | Nature Technology Corporation (Lincoln, Nebraska) |
| INVENTOR(S) | James A. Williams (Lincoln, Nebraska) |
| ABSTRACT | A eukaryotic replicative pUC-free minicircle expression vector is provided. The eukaryotic replicative pUC-free minicircle expression vector includes a pUC-free eukaryotic region sequence encoding a transgene of interest and comprising 5′ and 3′ ends and ii) a pUC-free spacer region of less than 500 basepairs in length linking the 5′ and 3′ ends of the eukaryotic region sequences and comprising a bacterial R6K replication origin having at least 95% sequence identity to SEQ ID NO: 11 or SEQ ID NO: 12 and a RNA selectable marker, the RNA selectable marker being an RNA-IN regulating RNA-OUT functional variant having at least 95% sequence identity to SEQ ID NO:20 or SEQ ID NO:22. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/016229 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/64 (20130101) C12N 15/67 (20130101) C12N 15/79 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 2800/24 (20130101) C12N 2800/107 (20130101) C12N 2820/55 (20130101) C12N 2830/42 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844403 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); James Angstman (Charlestown, Massachusetts); Jeffry D. Sander (Ankeny, Iowa); Morgan Maeder (Brookline, Massachusetts); Shengdar Tsai (Memphis, Tennessee) |
| ABSTRACT | Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870659 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/96 (20130101) C12N 9/1007 (20130101) C12N 15/01 (20130101) C12N 15/11 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1031 (20130101) C12N 2310/20 (20170501) C12N 2710/00033 (20130101) C12N 2770/00033 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 201/01 (20130101) C12Y 301/00 (20130101) C12Y 301/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844426 | Daugharthy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan R. Daugharthy (Cambridge, Massachusetts); Son C. Nguyen (West Roxbury, Massachusetts); Chao-ting Wu (Brookline, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to a method of identifying a target genomic nucleic acid sequence including hybridizing a set of probes to the target genomic nucleic acid sequence, wherein the set of probes has a unique associated barcode sequence for identification of the target genomic nucleic acid sequence, wherein each probe of the set includes (1) a complementary sequence complementary to a first strand of the target genomic nucleic acid sequence and (2) the associated barcode sequence or a portion of the associated barcode sequence, sequencing the associated barcode sequence from probes hybridized to the target genomic nucleic acid sequence using a fluorescence-based sequencing method, and identifying the target genomic nucleic acid sequence by the sequenced barcode sequence. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 16/085705 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 2535/00 (20130101) C12Q 2535/00 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/04 (20130101) C40B 40/08 (20130101) C40B 70/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844436 | Lyden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| INVENTOR(S) | David C. Lyden (New York, New York); Hector Peinado Selgas (New York, New York); Haiying Zhang (New York, New York); Basant Kumar Thakur (New York, New York); Annette Becker (New York, New York); Jacqueline Bromberg (West Nyack, New York) |
| ABSTRACT | The present invention is directed to methods of prognosing, treating, or managing treatment of cancer in a subject. These methods involve selecting a subject having cancer, obtaining, from the selected subject, a sample containing exosomes, recovering the exosomes from the sample, and isolating the double-stranded DNA from within the exosomes. The isolated double-stranded DNA is then used to detect the presence or absence of one or more genetic mutations associated with cancer, quantify the amount of isolated double-stranded DNA from the recovered exosomes in the sample, detect the methylation status of the isolated double-stranded DNA, or quantify the amount isolated double-stranded DNA able to enter a recipient cell. The prognosing, treating, or managing treatment is carried out based on this information. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 15/300639 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845366 | Gerner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Eugene Gerner (Tucson, Arizona); Edwin Paz (Durham, North Carolina); Bonnie Lafleur (Tucson, Arizona); Jenaro Garcia-Huidobro (Tucson, Arizona) |
| ABSTRACT | The present invention relates to therapeutic methods and medical uses comprising the identification and use of cancer marker surrogates for increased polyamine expression. These markers may be used to identify patients who may be treated for diseases and disorders that are susceptible to polyamine synthesis inhibitors, and they can also be used to monitor therapeutic responses when such agents are used. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172252 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/198 (20130101) A61K 31/198 (20130101) A61K 31/616 (20130101) A61K 31/616 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 33/57496 (20130101) Original (OR) Class G01N 2333/4703 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845368 | Dhar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Shanta Dhar (Miami, Florida); Sean M. Marrache (Portland, Oregon) |
| ABSTRACT | Nanoparticles include a core, a hydrophilic layer around the core, and one or more mitochondrial targeting moieties, and may optionally include one or more contrast agents or one or more therapeutic agents. For effective mitochondrial targeting the nanoparticles have a diameter of about 200 nm or less or have a zeta potential of about 0 mV or more. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530355 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 31/06 (20130101) A61K 31/12 (20130101) A61K 31/355 (20130101) A61K 31/416 (20130101) A61K 47/60 (20170801) A61K 47/548 (20170801) A61K 47/6937 (20170801) A61K 49/0067 (20130101) A61K 49/0093 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/587 (20130101) Original (OR) Class G01N 33/588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845446 | Reeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Scott B. Reeder (Middleton, Wisconsin); Xiaoke Wang (Madison, Wisconsin) |
| ABSTRACT | A system and method are provided for controlling a magnetic resonance imaging system to perform a gradient echo pulse sequence that includes varying a phase of an RF pulse of the gradient echo pulse sequence between repetitions and acquire complex MR data. The method includes processing the complex MR data to determine signal contributions from transverse relaxation (T2) in the subject, generating a quantitative T2 map of the subject using the signal contributions from T2 in the subject, and displaying the quantitative T2 map. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393806 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/543 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845447 | Edelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHSHORE UNIVERSITY HEALTH SYSTEM (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHSHORE UNIVERSITY HEALTHSYSTEM (Evanston, Illinois) |
| INVENTOR(S) | Robert R. Edelman (Highland Park, Illinois); Ioannis Koktzoglou (Des Plaines, Illinois) |
| ABSTRACT | A system and method for controlling a magnetic resonance imaging (MRI) system to create magnetic resonance (MR) angiograms of a subject. The method includes controlling the MRI system to acquire MR data by performing a pulse sequence that includes at least one set of modules formed by a first α/2 module, a (readout, α)n module, a second α/2 module. In this case, α denotes a radiofrequency (RF) flip angle and n denotes a number of times that the set of modules is repeated. The method also includes reconstructing an MR angiogram of the subject from the MR data. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/040730 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0452 (20130101) A61B 5/7285 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5607 (20130101) G01R 33/5614 (20130101) G01R 33/5635 (20130101) Original (OR) Class G01R 33/5673 (20130101) G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846251 | Caccamo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Marco Caccamo (Urbana, Illinois); Rodolfo Pellizzoni (Waterloo, Canada); Renato Mancuso (Urbana, Illinois); Rohan Tabish (Urbana, Illinois); Saud Wasly (Jeddah, Saudi Arabia) |
| ABSTRACT | An embodiment may involve determining that a first logical partition of a scratchpad memory coupled to a processor core is empty and a first application is scheduled to execute; instructing a direct memory access (DMA) engine to load the first application into the first logical partition and then instructing the processor core to execute the first application from the first logical partition; while the first application is being executed from the first logical partition, determining that a second logical partition of the scratchpad memory is empty and a second application is scheduled to execute; instructing the DMA engine to load the second application into the second logical partition; determining that execution of the first application has completed; and instructing the DMA engine to unload the first application from the first logical partition and instructing the processor core to execute the second application from the second logical partition. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/840005 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 3/061 (20130101) G06F 3/0656 (20130101) G06F 3/0683 (20130101) G06F 9/5077 (20130101) G06F 13/28 (20130101) Original (OR) Class G06F 13/1673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846367 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Xiangxue Wang (Cleveland Heights, Ohio); Pranjal Vaidya (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio) |
| ABSTRACT | Embodiments predict early stage NSCLC recurrence, and include processors configured to access a pathology image of a region of tissue demonstrating early stage NSCLC; extract a set of pathomic features from the pathology image; access a radiological image of the region of tissue; extract a set of radiomic features from the radiological image; generate a combined feature set that includes at least one member of the set of pathomic features, and at least one member of the set of radiomic features; compute a probability that the region of tissue will experience NSCLC recurrence based, at least in part, on the combined feature set; and classify the region of tissue as recurrent or non-recurrent based, at least in part, on the probability. Embodiments may display the classification, or generate a personalized treatment plan based on the classification. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/131570 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 19/00 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00127 (20130101) G06K 9/3233 (20130101) G06K 9/4619 (20130101) G06K 9/4628 (20130101) G06K 9/6218 (20130101) G06K 9/6234 (20130101) G06K 9/6273 (20130101) G06K 9/6277 (20130101) G06K 9/6286 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) G06N 3/0472 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/0012 (20130101) G06T 7/0016 (20130101) G06T 2207/10004 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) G16H 20/40 (20180101) G16H 30/40 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846856 | Heine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institure, Inc. (Tampa, Florida) |
| INVENTOR(S) | John J. Heine (New Port Richey, Florida); Thomas A. Sellers (Tampa, Florida); Erin E. Fowler (Tampa, Florida) |
| ABSTRACT | Breast density is a significant breast cancer risk factor measured from mammograms. Disclosed is a methodology for converting continuous measurements of breast density and calibrated mammograms into a four-state ordinal variable approximating the BI-RADS ratings. In particular, the present disclosure is directed to a calibration system for a specific full field digital mammography (FFDM) technology. The calibration adjusts for the x-ray acquisition technique differences across mammograms resulting in standardized images. The approach produced various calibrated and validated measures of breast density, one of which assesses variation in the mammogram referred to as Vc (i.e. variation measured from calibrated mammograms). The variation in raw mammograms [i.e. Vr] is a valid breast density risk factor in both FFDM in digitized film mammograms. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422040 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/502 (20130101) A61B 6/583 (20130101) A61B 6/5205 (20130101) A61B 6/5217 (20130101) Image Data Processing or Generation, in General G06T 5/40 (20130101) G06T 7/0014 (20130101) Original (OR) Class G06T 7/44 (20170101) G06T 7/90 (20170101) G06T 2207/10116 (20130101) G06T 2207/30068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846858 | Small et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Scott A. Small (Millerton, New York); Frank A. Provenzano (New York, New York); Usman A. Khan (Brooklyn, New York) |
| ABSTRACT | A technology which enables identifying, via a computer, a vessel in a third image. The third image is obtained from a subtraction of a second image from a first image. The second image and the first image are aligned within an imaging space. The first image is post-contrast. The second image is pre-contrast. The technology enables determining, via the computer, a voxel intensity mean value of a segment of the vessel in the third image. The technology enables obtaining, via the computer, a fourth image from a division of the third image by the voxel intensity mean value. The technology enables applying, via the computer, a filter onto the fourth image. The technology enables generating, via the computer, a filter mask based on the fourth image. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/267067 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 5/50 (20130101) G06T 7/11 (20170101) G06T 7/0016 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 2207/10088 (20130101) G06T 2207/20224 (20130101) G06T 2207/30016 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846928 | Alterovitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Ron Alterovitz (Chapel Hill, North Carolina); Luis Guillermo Torres (Carrboro, North Carolina); Philip Joseph Swaney (Nashville, Tennessee); Hunter Bryant Gilbert (Nashville, Tennessee); Robert James Webster (Nashville, Tennessee); Richard Joseph Hendrick (Nashville, Tennessee) |
| ABSTRACT | Systems for controlling concentric tube probes are disclosed. In some examples, the system includes a concentric tube position display interface and a control system. The concentric tube display interface includes a display for displaying visual feedback to a user indicating a position (and possibly orientation) of a tip of a concentric tube probe and a user input device for receiving user input from the user designating a goal position (and possibly orientation) for the tip of the concentric tube probe. The control system is configured for interactive-rate motion planning of the concentric tube probe by creating, in real-time or near real-time, a motion plan to move the tip of the concentric tube probe to the goal position (and possibly orientation) while avoiding contact by the concentric tube probe with one or more obstacles and for configuring the concentric tube probe as specified by the motion plan. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/576619 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/01 (20130101) A61B 1/2676 (20130101) A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2034/301 (20160201) Image Data Processing or Generation, in General G06T 19/00 (20130101) G06T 19/003 (20130101) Original (OR) Class G06T 2210/21 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847278 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Ou Chen (Somerville, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ABSTRACT | Multifunctional nanoparticles can include two or more different populations of nanocrystals that impart a combination of properties arising from the constituent populations in a single, multifunctional nanoparticle. |
| FILED | Saturday, February 23, 2019 |
| APPL NO | 16/283750 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0093 (20130101) A61K 49/1818 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) Y10T 428/2993 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848519 | Howard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles River Analytics, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Charles River Analytics, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Howard (Watertown, Massachusetts); Avi Pfeffer (Cambridge, Massachusetts); Mukesh Dalal (Carlisle, Massachusetts); Michael Reposa (Lynn, Massachusetts) |
| ABSTRACT | Methods and systems for Predictive Malware Defense (PMD) are described. The systems and methods can utilize advanced machine-learning (ML) techniques to generate malware defenses preemptively. Embodiments of PMD can utilize models, which are trained on features extracted from malware families, to predict possible courses of malware evolution. PMD captures these predicted future evolutions in signatures of as yet unseen malware variants to function as a malware vaccine. These signatures of predicted future malware “evolutions” can be added to the training set of a machine-learning (ML) based malware detection and/or mitigation system so that it can detect these new variants as they arrive. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/159067 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/57 (20130101) G06F 21/552 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) G06N 20/10 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) H04L 63/145 (20130101) Original (OR) Class H04L 63/1416 (20130101) H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10842504 | Gordon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); The United Dtates of America, as represented by the Secretary of the Navy (Washington, District of Columbia); The United States of America, as represented by the Secretary of Defense (Washington, District of Columbia) |
| INVENTOR(S) | Chad Gordon (Cockeysville, Maryland); Mehran Armand (Fulton, Maryland); Ryan Murphy (Columbia, Maryland); Gerald Grant (Goshen, Kentucky); Peter Liacouras (North Potomac, Maryland); Kevin Wolfe (Lutherville, Maryland); Ehsan Basafa (Baltimore, Maryland) |
| ABSTRACT | A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 16/561984 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/15 (20130101) Original (OR) Class A61B 17/176 (20130101) A61B 17/1695 (20130101) A61B 17/1739 (20130101) A61B 17/8085 (20130101) A61B 34/10 (20160201) A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/108 (20160201) A61B 2034/2051 (20160201) A61B 2034/2055 (20160201) A61B 2034/2065 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2803 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/50 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842748 | DeSimone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Agoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689733 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842749 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Haifa Shen (Bellaire, Texas); Mauro Ferrari (Houston, Texas); Xiaoyong Deng (Houston, Texas); Guodong Zhang (Sugar Land, Texas) |
| ASSIGNEE(S) | The Methodist Hospital Research Institute (Houston, Texas) |
| INVENTOR(S) | Haifa Shen (Bellaire, Texas); Mauro Ferrari (Houston, Texas); Xiaoyong Deng (Houston, Texas); Guodong Zhang (Sugar Land, Texas) |
| ABSTRACT | The present disclosure is directed to a composition for the sustained-release delivery of an active agent to a target cell of an individual. The compositions disclosed herein comprise of at least one porous particle; at least one polymer; and at least one active agent. In an embodiment, the porous particle comprises a plurality of microscale reservoirs. In an exemplary embodiment, the at least one active agent is covalently linked to the at least one polymer to form a polymer-active agent conjugate, and the polymer-active agent conjugate is contained in the plurality of microscale reservoirs of the porous particle. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual the composition described supra. Additionally, disclosed herein is a method of eliminating tumor stem cells. Furthermore, there is provided a method of circumventing multi-drug resistance in a tumor cell. |
| FILED | Wednesday, June 12, 2013 |
| APPL NO | 13/916380 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/146 (20130101) Original (OR) Class A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842767 | D'Agostino et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Dominic Paul D'Agostino (Tampa, Florida); Jay B. Dean (Land O'Lakes, Florida); Raffaele Pilla (Tampa, Florida); Patrick Arnold (Champaign, Illinois) |
| ABSTRACT | The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and Aβ-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two. |
| FILED | Tuesday, November 12, 2013 |
| APPL NO | 14/078066 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/22 (20130101) A61K 31/225 (20130101) Original (OR) Class A61K 31/225 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842849 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 14/002033 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 9/0085 (20130101) A61K 9/5169 (20130101) A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 35/30 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/30 (20130101) A61K 38/1703 (20130101) A61K 38/1709 (20130101) A61K 38/1738 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 49/0056 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 2501/105 (20130101) C12N 2502/08 (20130101) C12N 2502/081 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/5073 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842855 | Lyerly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering the cancer therapeutic or prevention agent and a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding an ESR1 polypeptide or a truncation, deletion or substitution mutant thereof. Methods of using the vaccine including the polynucleotide encoding the ESR1 polypeptide to treat a cancer or precancer are also provided. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044269 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842856 | Peoples et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | George E. Peoples (Spring Branch, Texas); Sathibalan Ponniah (Columbia, Maryland) |
| ABSTRACT | The invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75, with the effect of inducing and maintaining protective or therapeutic immunity against breast cancer in a patient in clinical remission. The methods comprise administering to the patient an effective amount of a vaccine composition comprising a pharmaceutically acceptable carrier, an adjuvant such as recombinant human GM-CSF, and the E75 peptide at an optimized dose and schedule. The methods further comprise administering an annual or semi-annual booster vaccine dose due to declining E75-specific T cell immunity. The invention also features vaccine compositions for use in the methods. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912156 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/179 (20130101) A61K 38/193 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/001106 (20180801) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842857 | Lyerly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding a HER2 polypeptide or a truncation, deletion or substitution mutant thereof. Methods of using the vaccine including the polynucleotide encoding the HER2 polypeptide to treat a cancer or precancer are also provided. The vaccines may be administered with a cancer therapeutic or prevention agent or a checkpoint inhibitor immunomodulatory agent. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045248 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 39/0011 (20130101) A61K 39/0011 (20130101) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/53 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842874 | Collins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James J. Collins (Newton, Massachusetts); Michael Andrew Lobritz (Basel, Switzerland); Arnaud Gutierrez (Somerville, Massachusetts) |
| ABSTRACT | Provided herein are pharmaceutical compositions and kits useful for sensitizing a microorganism or a population of microorganisms to a quinolone antibiotic. In a particular aspect, a carbon source and an electron acceptor can sensitize an antibiotic persistent microorganism to treatment with a fluoroquinolone antibiotic. Methods for sensitizing a microorganism to a quinolone antibiotic, reducing the density-dependent persistence (DDP) of an antibiotic resistant microorganism, and reducing the number of persistent cells in a population are also provided. Theses compositions and methods are useful in treating infections resulting from high-density bacterial cultures, such as pneumonia, genitourinary infections, biofilms, prosthetic graft infections, sepsis, and endovascular infections. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/168628 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) A61K 31/194 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/4741 (20130101) A61K 31/4741 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 31/7004 (20130101) A61K 31/7004 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/12 (20130101) A61K 47/26 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842908 | Kudela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Damien Kudela (Santa Barbara, California); Galen D Stucky (Santa Barbara, California); Anna May-Masnou (Barcelona, Spain); Gary Bernard Braun (San Diego, California); James H Morrissey (Champaign, Illinois); Stephanie A Smith (Urbana, Illinois) |
| ABSTRACT | A hemostatic composition is provided. The hemostatic composition includes a hemostatically effective amount of a hemostatic agent that includes a nanoparticle and a polyphosphate polymer attached to the nanoparticle. Also provided are medical devices and methods of use to promote blood clotting. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/390451 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/595 (20170801) A61K 47/6923 (20170801) A61K 47/6935 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 2300/404 (20130101) A61L 2300/418 (20130101) A61L 2400/04 (20130101) A61L 2400/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842932 | Bibian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stéphane Bibian (Cleveland Heights, Ohio); Sankar Barua (Stow, Ohio); Tatjana Zikov (Cleveland Heights, Ohio) |
| ASSIGNEE(S) | NeuroWave Systems Inc. (Cleveland Heights, Ohio) |
| INVENTOR(S) | Stéphane Bibian (Cleveland Heights, Ohio); Sankar Barua (Stow, Ohio); Tatjana Zikov (Cleveland Heights, Ohio) |
| ABSTRACT | The present invention relates to the titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering such medications in a semi-automated or fully automated manner and which can be monitoring and controlled remotely. Even still further, the present invention relates to such a device that can perform the titration and delivery of medication in a manner that minimalizes occlusion and prevents back flow of the medication. More particularly, the present invention relates to a device for titration and delivery of medication using a non-concentric pumping mechanism that gradual or progressively increases and decreases occlusion in the medication delivery line within the pump to minimize and/or prevent sudden formation and release of occlusion in order to provide more steady and continuous flow of the medication through the device to the subject. |
| FILED | Tuesday, July 19, 2016 |
| APPL NO | 15/213489 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1684 (20130101) Original (OR) Class A61M 5/14232 (20130101) A61M 19/00 (20130101) A61M 2005/16863 (20130101) A61M 2205/14 (20130101) A61M 2205/18 (20130101) A61M 2205/332 (20130101) A61M 2205/6063 (20130101) A61M 2230/005 (20130101) A61M 2230/10 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/1238 (20130101) F04B 43/1253 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 5/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843162 | DuBois |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Terry DuBois (Forest Hill, Maryland) |
| ABSTRACT | Various embodiments that pertain to oxygen enrichment are described. Oxygen enrichment is shown to allow for independent control of both reformer residence time and the oxygen-to-carbon ratio during reforming. This allows for much better control over the reformer and for significant gains in reformer through-put without negative impacts to reformer performance. Additionally, the use of oxygen enriched reforming is shown to result in enhanced reformer performance, reduced degradation from catalyst poisons (carbon formation and sulfur) and enhanced fuel cell stack performance due to greatly increased hydrogen concentration in the reformate. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/951236 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) B01J 19/0013 (20130101) B01J 19/24 (20130101) Original (OR) Class B01J 2219/24 (20130101) B01J 2219/00063 (20130101) B01J 2219/00065 (20130101) B01J 2219/00069 (20130101) B01J 2219/00087 (20130101) B01J 2219/00117 (20130101) B01J 2219/00159 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/38 (20130101) C01B 13/0251 (20130101) C01B 2203/0227 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843189 | Hung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Paul J. Hung (Berkeley, California); Philip J. Lee (Alameda, California); Luke P. Lee (Orinda, California) |
| ABSTRACT | Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/925445 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/027 (20130101) B01L 2200/0647 (20130101) B01L 2200/0689 (20130101) B01L 2300/0627 (20130101) B01L 2300/0816 (20130101) B01L 2400/086 (20130101) B01L 2400/088 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/05 (20130101) B81B 2201/06 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/019 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 23/34 (20130101) C12M 29/06 (20130101) C12M 29/10 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843332 | Walsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellow of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Conor J. Walsh (Cambridge, Massachusetts); Alan Thomas Asbeck (Cambridge, Massachusetts); Ye Ding (Cambridge, Massachusetts); Ignacio Galiana Bujanda (Cambridge, Massachusetts); Stefano Marco Maria De Rossi (Cambridge, Massachusetts) |
| ABSTRACT | A motion control system includes an actuator having an actuation member, the actuation member having a proximal end attached to the actuator on a first side of a joint and a distal end attached to an anchor element attachment point on a second side of the joint. A first sensor is configured to output signals defining a gait cycle and a second sensor is configured to output signals representing a tensile force in the at least one actuation member. A controller receives the output signals from the sensors and actuates the actuator, during a first portion of the gait cycle, to apply a force greater than a predetermined threshold tensile force to the anchor element attachment point via the actuation member to generate a beneficial moment about the joint and to automatically actuate the actuator. |
| FILED | Friday, May 30, 2014 |
| APPL NO | 14/893934 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/6812 (20130101) A61B 5/6828 (20130101) A61B 5/6831 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0266 (20130101) A61H 3/00 (20130101) A61H 2003/001 (20130101) A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/1215 (20130101) A61H 2201/1238 (20130101) A61H 2201/1253 (20130101) A61H 2201/1628 (20130101) A61H 2201/1676 (20130101) A61H 2201/5046 (20130101) A61H 2201/5048 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) A61H 2230/60 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/008 (20130101) A63B 21/023 (20130101) A63B 21/0054 (20151001) A63B 21/152 (20130101) A63B 21/00178 (20130101) A63B 21/4009 (20151001) A63B 21/4013 (20151001) A63B 21/4015 (20151001) A63B 21/4025 (20151001) A63B 21/4047 (20151001) A63B 23/0405 (20130101) A63B 23/03541 (20130101) A63B 24/0087 (20130101) A63B 2071/068 (20130101) A63B 2071/0666 (20130101) A63B 2220/24 (20130101) A63B 2220/40 (20130101) A63B 2220/51 (20130101) A63B 2220/801 (20130101) A63B 2225/20 (20130101) A63B 2225/50 (20130101) A63B 2230/60 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/104 (20130101) B25J 9/1694 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/005 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843336 | Kwok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sen Wai Kwok (Watertown, Massachusetts); Stephen A. Morin (Lincoln, Nebraska); Bobak Mosadegh (New York, New York); Ju-Hee So (Seoul, South Korea); Robert F. Shepherd (Brooktondale, New York); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | Reconfigurable soft robotic actuators with hard components are described. Magnetic attraction is used to couple flexible molded bodies capable of actuation upon pressurization with other flexible molded bodies and/or with hard components (e.g., frames and connectors) to form a seal for fluidic communication and cooperative actuation. Pneumatic de-coupling chambers built into the hard components to de-couple the hard components from the magnetically-coupled soft molded bodies are described. The use of magnetic self-alignment coupling and pneumatic de-coupling allows for the remote assembly and disassembly of complex structures involving hard and soft components. The magnetic coupling allows for rapid, reversible reconfiguration of hybrid soft-hard robots for repair, testing new designs, and carrying out new tasks. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/974444 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Toys, e.g Tops, Dolls, Hoops or Building Blocks A63H 3/46 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/04 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/08 (20130101) B25J 9/14 (20130101) Original (OR) Class B25J 9/142 (20130101) B25J 15/12 (20130101) B25J 15/0023 (20130101) B25J 15/0608 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/27 (20130101) Y10S 901/37 (20130101) Y10S 901/39 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843549 | Morrow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| ASSIGNEE(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| INVENTOR(S) | Jon Morrow (Neenah, Wisconsin); Dave Steinberger (Oshkosh, Wisconsin); Eric Braun (Oshkosh, Wisconsin); Andrew Kotloski (Oshkosh, Wisconsin); Nader Nasr (Neenah, Wisconsin) |
| ABSTRACT | A drive train includes a first gear set including a sun gear, a ring gear and planetary gears coupling the sun gear to the ring gear, a second gear set including a sun gear, a ring gear and planetary gears coupling the sun gear to the ring gear, a first motor/generator coupled to the first gear set, a second motor/generator coupled to the second gear set, a first clutch that selectively engages the second motor/generator with the first gear set, and a second clutch that selectively engages the ring gear of the second gear set with the planetary gear carrier of at least one of the first gear set and the second gear set. The planetary gears of both sets are rotatably supported by respective planetary gear carriers. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/592167 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/52 (20130101) Original (OR) Class B60K 6/365 (20130101) B60K 6/445 (20130101) B60K 6/543 (20130101) Gearing F16H 3/728 (20130101) F16H 37/065 (20130101) F16H 2037/088 (20130101) F16H 2037/102 (20130101) F16H 2037/106 (20130101) F16H 2037/0866 (20130101) F16H 2200/201 (20130101) F16H 2200/2007 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/76 (20130101) Y02T 10/6239 (20130101) Y02T 10/6265 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 903/902 (20130101) Y10S 903/911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843783 | Cranston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Brian Cranston (Dayton, Ohio); Anthony Palazotto (Dayton, Ohio) |
| ABSTRACT | A vacuum lighter than air vehicle (VLTAV) includes a rigid frame of rods connected together to form a hexakis icosahedron. A membrane skin covers the rigid frame and defines therewith a vessel configured to hold an internal vacuum that allows the vessel to float in the air. The plurality of rods and membrane skin have weights and dimensions that result in a neutral and/or positive buoyancy for the vessel while preventing geometric instability. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/843540 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) B32B 27/32 (20130101) B32B 2262/0253 (20130101) B32B 2605/18 (20130101) Lighter-than Air Aircraft B64B 1/08 (20130101) Original (OR) Class B64B 1/12 (20130101) B64B 1/16 (20130101) B64B 1/20 (20130101) B64B 1/30 (20130101) B64B 1/62 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 2211/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844185 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois); Piyush R. Thakre (Lake Jackson, Texas) |
| ABSTRACT | A thermally degradable polymeric sheet, comprising: a poly(hydroxyalkanoate); and a metal selected from the group consisting of an alkali earth metal and a transition metal; where the volume fraction of the metal in the sheet is at least 0.1 vol %. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/138573 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2022/007 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2367/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24744 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844230 | Babilo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Peter Babilo (Mission Viejo, California); Giuseppe A. Russo (Orange, California) |
| ABSTRACT | The present disclosure relates to highly reflective coating formulations that produce coatings having an average infrared reflectivity ranging from about 75% to about 90% at wavelengths ranging from about 0.5 μm to about 1000 μm, methods for making the coatings and coating mixtures, and substrates comprising such coatings. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 15/426635 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/5006 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 2003/0812 (20130101) C08K 2003/0812 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) Original (OR) Class C09D 163/00 (20130101) C09D 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844365 | Souza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Glauco R. Souza (Houston, Texas); Renata Pasqualini (Houston, Texas); Wadih Arap (Houston, Texas); Thomas Charles Killian (Houston, Texas); Robert M. Raphael (Houston, Texas); Daniel Joshua Stark (Houston, Texas) |
| ABSTRACT | Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912165 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844436 | Lyden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| INVENTOR(S) | David C. Lyden (New York, New York); Hector Peinado Selgas (New York, New York); Haiying Zhang (New York, New York); Basant Kumar Thakur (New York, New York); Annette Becker (New York, New York); Jacqueline Bromberg (West Nyack, New York) |
| ABSTRACT | The present invention is directed to methods of prognosing, treating, or managing treatment of cancer in a subject. These methods involve selecting a subject having cancer, obtaining, from the selected subject, a sample containing exosomes, recovering the exosomes from the sample, and isolating the double-stranded DNA from within the exosomes. The isolated double-stranded DNA is then used to detect the presence or absence of one or more genetic mutations associated with cancer, quantify the amount of isolated double-stranded DNA from the recovered exosomes in the sample, detect the methylation status of the isolated double-stranded DNA, or quantify the amount isolated double-stranded DNA able to enter a recipient cell. The prognosing, treating, or managing treatment is carried out based on this information. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 15/300639 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844944 | Bloxham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Keith Bloxham (Gilbert, Arizona); Derick S. Balsiger (Mayer, Arizona) |
| ABSTRACT | An inverted harmonic gear actuator is provided and includes a motor stator and a motor rotor radially disposed within the motor stator. The inverted harmonic gear actuator also includes a wave generator radially disposed within the motor rotor, where the wave generator has a radially inner surface with a cammed shape. An actuator output shaft is radially disposed within the wave generator. A flex spline is radially interposable between the radially inner surface of the wave generator and the actuator output shaft. The flex spline is deformable to conform to the radially inner surface of the wave generator and drive rotation of the actuator output shaft slower than rotation of the motor rotor. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686375 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Gearing F16H 49/001 (20130101) Original (OR) Class F16H 2049/003 (20130101) Dynamo-electric Machines H02K 7/116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845067 | Martin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Energy and Enviornmental Research Center (Grand Forks, North Dakota) |
| INVENTOR(S) | Christopher Lee Martin (Grand Forks, North Dakota) |
| ABSTRACT | In various embodiments, the present invention relates to heat dissipation systems including a hygroscopic working fluid integrating waste water as makeup water. The present invention also relates to methods of using the same. The present invention also relates to hygroscopic cooling systems adapted to dispose of waste water by combining the waste water with a hygroscopic working fluid, precipitating impurities and evaporating the remaining water. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/918916 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 9/003 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 5/0035 (20130101) F24F 2003/144 (20130101) Steam or Vapour Condensers F28B 9/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/02 (20130101) F28C 1/04 (20130101) F28C 1/16 (20130101) F28C 2001/006 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 23/02 (20130101) F28F 25/02 (20130101) F28F 25/12 (20130101) F28F 25/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845174 | Little et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Gregory D. Little (Ashland, Virginia); John-Paul Shebalin (Chapel Hill, North Carolina); James S. Fetsko (Fredericksburg, Virginia); Joseph A. Silber (King George, Virginia); Christopher N. Davidson (King George, Virginia); John E. Brough (Fredericksburg, Virginia) |
| ABSTRACT | An ammunition tray is provided for containing a plurality of bullet cartridges within an ammunition box container having a stowage volume. The tray includes a substantially rectangular template having a horizontal surface bounded by first and second opposing longitudinal edges and opposing lateral edges joined at four corners. Each longitudinal edge includes a first tab bent substantially perpendicular to the surface in a vertical direction to form a rib. Each lateral edge includes a second tab bent substantially perpendicular to the surface to form a wall. The surface includes a first row of interior pockets that point towards the first longitudinal edge as a proximal orientation. The surface further includes a second row of interior pockets that point towards the second longitudinal edge as a distal orientation. The template has longitudinal and lateral edges bent to form the respective ribs and walls fits within the stowage volume as a vertical stack of plural templates. Each first interior pocket in the first row can cradle a cartridge on the surface along the proximal orientation, can fit the cartridge from an adjacent second row, and has lateral edges bent to curl in said vertical direction. Each second interior pocket in the second row can cradle the cartridge on the surface along the distal orientation, can fit the cartridge from an adjacent first row, and has lateral edges bent to curl opposite said vertical direction. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157394 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 30/08 (20130101) F42B 39/22 (20130101) F42B 39/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845211 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida); Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson, Ohio) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Chengying Xu (Tallahassee, Florida); Amanda Schrand (Eglin, Florida); Reamonn Soto (Daytona Beach, Florida) |
| ABSTRACT | Temperature sensors, pressure sensors, methods of making the same, and methods of detecting pressures and temperatures using the same are provided. In an embodiment, the temperature sensor includes a ceramic coil inductor having a first end plate and a second end plate, wherein the ceramic coil inductor is formed of a ceramic composite that comprises carbon nanotubes or, carbon nanofibers, or a combination of carbon nanotubes and carbon nanofibers thereof dispersed in a ceramic matrix; and a thin film polymer-derived ceramic (PDC) nanocomposite disposed between the first and the second end plates, wherein the thin film PDC nanocomposite has a dielectric constant that increases monotonically with temperature. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863150 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 3/08 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/32 (20130101) G01K 7/343 (20130101) G01K 2211/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/007 (20130101) G01L 9/105 (20130101) G01L 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845295 | Jalali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric D. Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/528426 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 33/537 (20130101) G01N 2015/1006 (20130101) G01N 2015/1477 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845349 | Ensor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina) |
| INVENTOR(S) | David S. Ensor (Chapel Hill, North Carolina); Li Han (Research Triangle Park, North Carolina) |
| ABSTRACT | A chemical sensor and a system and method for sensing a chemical species. The chemical sensor includes a plurality of nanofibers whose electrical impedance varies upon exposure to the chemical species, a substrate supporting and electrically isolating the fibers, a set of electrodes connected to the plurality of fibers at spatially separated points to permit the electrical impedance of the plurality of fibers to be measured, and a membrane encasing the fibers and having a thickness ranging from 50 μm to 5.0 mm. The system includes the chemical sensor, an impedance measuring device coupled to the electrodes and configured to determine an electrical impedance of the plurality of fibers, and an analyzer configured to identify the chemical species based on a change in the electrical impedance. The method measures at least one change in an electrical impedance between spatially separated electrodes connected to a plurality of fibers upon exposure of the fibers to the chemical species, and identifies the chemical species based on the measured change in the electrical impedance. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580683 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 27/227 (20130101) G01N 33/0047 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845461 | Phelan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brian R. Phelan (Silver Spring, Maryland); Marc Allan Ressler (College Park, Maryland); Kenneth I. Ranney (Monrovia, Maryland) |
| ABSTRACT | Embodiments of the present invention implement a novel methodology for processing radar image data from a radar system having one or more transmitter and receiver antenna pairs. The novel methodology deliberately operates on spectrally-notched radar data. It uses a specially-adapted version of the CLEAN algorithm to mitigate the effects of frequency-band notching. Following that, it performs a non-linear sidelobe-reduction algorithm to further eliminate artifacts and produce radar imagery of much higher quality. In some cases, it exploits a specific version of the recursive sidelobe minimization (RSM) algorithm which operates in the frequency and aperture (spatial) domain. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/000452 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/023 (20130101) G01S 7/295 (20130101) Original (OR) Class G01S 7/2813 (20130101) G01S 7/2955 (20130101) G01S 13/89 (20130101) G01S 13/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845671 | McManamon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Exciting Technology, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | Exciting Technology, LLC (Dayton, Ohio) |
| INVENTOR(S) | Paul F. McManamon (Dayton, Ohio); Abtin Ataei (Dayton, Ohio) |
| ABSTRACT | This disclosure teaches a thin film beam steering system comprising either flat or tilted transparent electrodes on one side of the electro-optical crystal layer and a transparent ground electrode on the other side. There is an insulator between each adjacent electrode which can be inserted all the way or partially through the EO crystal layer. A mirror layer can also be attached to the ground electrode. The refractive index of the EO crystal layer is changeable as a function of varying an applied voltage generated by the voltage supply and applied to the EO crystal layer. The disclosure also includes bulk crystal beam steering systems to steer a beam in 2 dimensions and to a wider angle. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 15/796055 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/29 (20130101) Original (OR) Class G02F 2201/12 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846329 | Nicotera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Paul Nicotera (Ithaca, New York); Kenneth McVearry (Dewitt, New York) |
| ABSTRACT | At least one processor of a computing device may determine relevancy metadata associated with of images stored in an imagery processing system. The at least one processor may determine one or more active retention policies for the images based at least in part on the relevancy metadata, wherein the one or more active retention policies include one or more rulesets that are applied to the relevancy metadata. The at least one processor may determine retention priority values associated with the images stored in the imagery processing system based at least in part on the one or more active retention policies. The at least one processor may manage retention of the images in the imagery processing system based at least in part on the retention priority values associated with the images. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885194 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/125 (20190101) G06F 16/5866 (20190101) Original (OR) Class Image Data Processing or Generation, in General G06T 1/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846367 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Xiangxue Wang (Cleveland Heights, Ohio); Pranjal Vaidya (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio) |
| ABSTRACT | Embodiments predict early stage NSCLC recurrence, and include processors configured to access a pathology image of a region of tissue demonstrating early stage NSCLC; extract a set of pathomic features from the pathology image; access a radiological image of the region of tissue; extract a set of radiomic features from the radiological image; generate a combined feature set that includes at least one member of the set of pathomic features, and at least one member of the set of radiomic features; compute a probability that the region of tissue will experience NSCLC recurrence based, at least in part, on the combined feature set; and classify the region of tissue as recurrent or non-recurrent based, at least in part, on the probability. Embodiments may display the classification, or generate a personalized treatment plan based on the classification. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/131570 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 19/00 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00127 (20130101) G06K 9/3233 (20130101) G06K 9/4619 (20130101) G06K 9/4628 (20130101) G06K 9/6218 (20130101) G06K 9/6234 (20130101) G06K 9/6273 (20130101) G06K 9/6277 (20130101) G06K 9/6286 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) G06N 3/0472 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/0012 (20130101) G06T 7/0016 (20130101) G06T 2207/10004 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) G16H 20/40 (20180101) G16H 30/40 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846391 | Bonney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Jordan C. Bonney (Bloomington, Minnesota); Ranga Ramanujan (Medina, Minnesota) |
| ABSTRACT | In general, the techniques of this disclosure describe a computing device in a secure domain that is configured to receive, via a guard device, an authentication factor from at least one authentication device of a plurality of authentication devices each in a non-secure domain. The respective authentication factor comprises a respective identifier of a respective user of the respective authentication device. The computing device may then determine whether the respective user of each respective authentication device is a particular trusted user based on the received authentication factors. Responsive to determining that the respective user of each respective authentication device is the particular trusted user, the computing device may enable access to one or more applications on the computing device. Once access is enabled, the computing device may continue to enable access so long as the authentication devices send additional authentication factors that confirm the identity of the user. |
| FILED | Tuesday, January 09, 2018 |
| APPL NO | 15/866097 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/40 (20130101) G06F 21/43 (20130101) Original (OR) Class G06F 21/44 (20130101) G06F 21/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846567 | Andreopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Rathinakumar Appuswamy (San Jose, California); Pallab Datta (San Jose, California); Steven K. Esser (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention provide a method for scene understanding based on a sequence of image frames. The method comprises converting each pixel of each image frame to neural spikes, and extracting features from the sequence of image frames by processing neural spikes corresponding to pixels of the sequence of image frames. The method further comprises encoding the extracted features as neural spikes, and classifying the extracted features. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/592662 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/52 (20130101) G06K 9/66 (20130101) G06K 9/00718 (20130101) G06K 9/00986 (20130101) G06K 9/4623 (20130101) G06K 9/4652 (20130101) G06K 9/4661 (20130101) G06K 9/4671 (20130101) G06K 9/4676 (20130101) G06K 9/6256 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0635 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) Pictorial Communication, e.g Television H04N 9/67 (20130101) H04N 19/136 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846589 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| INVENTOR(S) | Ankit B. Patel (Houston, Texas); Richard G. Baraniuk (Houston, Texas) |
| ABSTRACT | A mechanism for compiling a generative description of an inference task into a neural network. First, an arbitrary generative probabilistic model from the exponential family is specified (or received). The model characterizes a conditional probability distribution for measurement data given a set of latent variables. A factor graph is generated for the generative probabilistic model. Each factor node of the factor graph is expanded into a corresponding sequence of arithmetic operations, based on a specified inference task and a kind of message passing algorithm. The factor graph and the sequences of arithmetic operations specify the structure of a neural network for performance of the inference task. A learning algorithm is executed, to determine values of parameters of the neural network. The neural network is then ready for performing inference on operational measurements. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/557793 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Original (OR) Class Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846606 | Levchuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts); Wright State University (Dayton, Ohio) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Georgiy Levchuk (South Grafton, Massachusetts); Jared Freeman (Bethesda, Maryland); Wayne Shebilske (Bellbrook, Ohio) |
| ABSTRACT | Embodiments of this invention comprise modeling a subject's state and the influence of training treatments, or actions, on that state to create a training policy. Both state and effects of actions are modeled as probabilistic using Partially Observable Markov Decision Process (POMDP) techniques. Utilizing this model and the resulting training policy with subjects creates an effective decision aid for instructors to improve learning relative to a traditional scenario selection strategy. |
| FILED | Monday, December 30, 2013 |
| APPL NO | 14/143410 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846834 | Fleizach |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gregory K. Fleizach (San Diego, California) |
| ABSTRACT | A shadow brightening method includes receiving, at a memory device, an original input image, a brightening level, and a threshold pixel intensity. If a pixel intensity is greater than the threshold, then the pixel is considered bright. Otherwise, the pixel is shadowed. The method includes calculating a gamma transformation for each pixel. If the pixel intensity is less than or equal to the threshold, then a gamma transformation equal to the received brightening level is applied. If the pixel intensity is greater than the threshold, then the gamma transformation is scaled to decrease with intensity. For each shadowed pixel, the method includes computing a minimum value. It also includes determining the brightening level to be applied, thus creating a gamma map. The method also includes applying the determined brightening level to the shadowed pixels and outputting a shadow-brightened output image. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280901 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4084 (20130101) G06T 5/009 (20130101) Original (OR) Class G06T 5/40 (20130101) G06T 2207/10024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846873 | Versace et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Neurala, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Neurala, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Massimiliano Versace (Boston, Massachusetts); Anatoly Gorshechnikov (Newton, Massachusetts) |
| ABSTRACT | Sensory processing of visual, auditory, and other sensor information (e.g., visual imagery, LIDAR, RADAR) is conventionally based on “stovepiped,” or isolated processing, with little interactions between modules. Biological systems, on the other hand, fuse multi-sensory information to identify nearby objects of interest more quickly, more efficiently, and with higher signal-to-noise ratios. Similarly, examples of the OpenSense technology disclosed herein use neurally inspired processing to identify and locate objects in a robot's environment. This enables the robot to navigate its environment more quickly and with lower computational and power requirements. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139466 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) G01S 7/41 (20130101) G01S 13/86 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/629 (20130101) G06K 9/00664 (20130101) G06K 9/3241 (20130101) G06K 9/4628 (20130101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) G06N 3/049 (20130101) G06N 3/0409 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847268 | Burnett |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Gregory M. Burnett (Dayton, Ohio) |
| ABSTRACT | Systems and associated methods for offline data transfer using exclusive point-to-point data communication between a transference device and a reception device. The transference device comprises an outputting subsystem configured to maintain a patient-specific chain-of-care data packet comprising patient-related identification data, health data, and sensor communication data. The transference device encodes the chain-of-care data packet in a machine-readable form (e.g, matrix barcode, haptic pulse, audio signal) that is detected by an appropriate component of the proximately-positioned reception device (e.g., camera, accelerometer, microphone) and decoded to create a cloned chain-of-care packet and to reestablish sensor communication for the subject patient through the reception device. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/192863 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 80/00 (20180101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 63/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847573 | Berggren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Susan Anne Elizabeth Berggren (San Diego, California); Benjamin J. Taylor (Escondido, California) |
| ABSTRACT | A device is disclosed that includes a substrate, a first superconducting quantum interference device (SQUID), a second SQUID and a third SQUID. The first SQUID is disposed on the substrate and has a first feature dimension, a second feature dimension and a first effective geometric magnetic inductance parameter value, βL1. The second SQUID is disposed on the substrate and has the first feature dimension, a third feature dimension and a second effective geometric magnetic inductance parameter value, βL2. The third SQUID is disposed on the substrate and has the first feature dimension, a fourth feature dimension and a third effective geometric magnetic inductance parameter value, βL3, wherein βL1<βL2<βL3. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/786659 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) Original (OR) Class H01L 39/025 (20130101) H01L 39/223 (20130101) H01L 39/2419 (20130101) Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847665 | Baehr-Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elenion Technologies, LLC (New York, New York) |
| ASSIGNEE(S) | Elenion Technologies, LLC (New York, New York) |
| INVENTOR(S) | Thomas Baehr-Jones (Arcadia, California); Yi Zhang (Jersey City, New Jersey); Michael J. Hochberg (New York, New York); Ari Novack (New York, New York) |
| ABSTRACT | A Ge-on-Si photodetector constructed without doping or contacting Germanium by metal is described. Despite the simplified fabrication process, the device has responsivity of 1.24 A/W, corresponding to 99.2% quantum efficiency. Dark current is 40 nA at −4 V reverse bias. 3-dB bandwidth is 30 GHz. |
| FILED | Friday, November 29, 2019 |
| APPL NO | 16/699363 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14638 (20130101) H01L 27/14649 (20130101) H01L 27/14685 (20130101) H01L 27/14698 (20130101) H01L 31/028 (20130101) H01L 31/105 (20130101) H01L 31/107 (20130101) H01L 31/0256 (20130101) H01L 31/0352 (20130101) Original (OR) Class H01L 31/1808 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847667 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Xing-Quan Liu (Arcadia, California); Christopher M. Fetzer (Valencia, California); Daniel C. Law (Arcadia, California); Richard R. King (Thousand Oaks, California) |
| ABSTRACT | In one aspect, semiconductor structures are described herein. A semiconductor structure, in some implementations, comprises a first semiconductor layer having a first bandgap and a first lattice constant and a second semiconductor layer having a second bandgap and a second lattice constant. The second lattice constant is lower than the first lattice constant. Additionally, a transparent metamorphic buffer layer is disposed between the first semiconductor layer and the second semiconductor layer. The buffer layer has a constant or substantially constant bandgap and a varying lattice constant. The varying lattice constant is matched to the first lattice constant adjacent the first semiconductor layer and matched to the second lattice constant adjacent the second semiconductor layer. The buffer layer comprises a first portion comprising AlyGazIn(1-y-z)As and a second portion comprising GaxIn(1-x)P. The first portion is adjacent the first semiconductor layer and the second portion is adjacent the second semiconductor layer. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/379141 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0392 (20130101) H01L 31/1844 (20130101) H01L 31/03046 (20130101) H01L 31/06875 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847706 | Ivry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts INSTITUTE of technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yachin Ivry (Brookline, Massachusetts); Jonathan J. Surick (Cambridge, Massachusetts); Karl Kimon Berggren (Arlington, Massachusetts) |
| ABSTRACT | A superconducting medium includes a first layer made of a first superconductor and a second layer made of a second superconductor. The first layer has a first thickness less than a first coherence length of the first superconductor. The second layer has a second thickness less than a second coherence length of the second superconductor so as to induce a proximity effect between the first layer and the second layer. The proximity effect can induce desirable properties in the resulting superconducting medium. Controlling the thickness ratio of the first layer to the second layer can also tune the property of the superconducting medium. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/907793 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/44 (20130101) G01J 5/10 (20130101) G01J 5/023 (20130101) G01J 5/024 (20130101) G01J 5/046 (20130101) G01J 2001/442 (20130101) G01J 2001/4446 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) Original (OR) Class H01L 39/12 (20130101) H01L 39/24 (20130101) H01L 39/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847726 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jianmin Shi (Rockville, Maryland); Eric W. Forsythe (Rockville, Maryland); David C. Morton (Columbia, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (, Washington) |
| INVENTOR(S) | Jianmin Shi (Rockville, Maryland); Eric W. Forsythe (Rockville, Maryland); David C. Morton (Columbia, Maryland) |
| ABSTRACT | The present invention relates to imidizo derivatives containing a plurality of imidizo moieties linked by aryl or heteroaryl groups. The resultant imidizo derivates may advantageously be used in organic electronic devices, such as multi-layer organic electroluminescent devices or organic photovoltaic devices, and in chemical sensing applications as a host material. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/120825 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Heterocyclic Compounds C07D 519/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0067 (20130101) Original (OR) Class H01L 51/0072 (20130101) H01L 51/5012 (20130101) H01L 51/5076 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847857 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Jonathan J. Lynch (Oxnard, California); Florian G. Herrault (Malibu, California) |
| ABSTRACT | An RF circulator in combination with a RF integrated circuit, the RF integrated circuit having a plurality of RF waveguide or waveguide-like structures in or on the RF integrated circuit, the RF circulator comprising a disk of ferrite material disposed on a metallic material disposed on or in the RF integrated circuit, the disk of ferrite material extending away from the RF integrated circuit when disposed thereon, the metallic portion having a plurality of apertures therein adjacent the disk of ferrite material which, in use, are in electromagnetic communication with the disk of ferrite material and with the plurality of RF waveguide or waveguide-like structures, the disk of ferrite material being disposed in a metallic cavity. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/396074 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 2223/6627 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/38 (20130101) Original (OR) Class H01P 3/003 (20130101) H01P 3/08 (20130101) H01P 3/081 (20130101) H01P 11/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847858 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Qorvo US, Inc. (Greensboro, North Carolina) |
| ASSIGNEE(S) | Qorvo US, Inc. (Greensboro, North Carolina) |
| INVENTOR(S) | Yu Cao (Allen, Texas); Yongjie Cui (Plano, Texas); Subrahmanyam V. Pilla (Plano, Texas) |
| ABSTRACT | A method for manufacturing a self-biased circulator includes cooling a nanocomposite material to a magnetization temperature below 200 K, applying an external magnetic field to the nanocomposite material to form a magnetic nanocomposite material, providing the magnetic nanocomposite material in a semiconductor substrate, and providing one or more metal layers over the magnetic nanocomposite material to form a circulator. By cooling and then magnetizing the nanocomposite material, a performance of the circulator may be significantly improved. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/427143 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8213 (20130101) H01L 21/8252 (20130101) H01L 23/66 (20130101) H01L 2223/6627 (20130101) H01L 2223/6683 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/387 (20130101) Original (OR) Class H01P 11/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848044 | Miesner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John E Miesner (Fairfax, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John E Miesner (Fairfax, Virginia) |
| ABSTRACT | The invention is an electromagnetic inertial force generator that provides a linear output with improved compactness and reliability because it has no radial gaps and only on pair of axial gaps. Radial permanent magnet rings are directly in contact with inner and outer flux cylinders to provide magnetic bias. The magnetic bias flux flows across two axial air gaps to a supporting flux return structure. A current conducting coil drives magnetic flux across the same axial air gaps. The magnetic bias flux is in opposite directions across the two air gaps while the coil flux across the two gaps is in the same direction. The combination of bias flux and coil flux cancels in one gap and add in the other gap producing a net force on an inertial mass and an equal and opposite force on the supporting structure. The resulting force is linear with current through the drive coil. |
| FILED | Monday, August 14, 2017 |
| APPL NO | 15/675901 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Dynamo-electric Machines H02K 33/06 (20130101) Original (OR) Class H02K 33/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848284 | Halepovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Illinois at Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Emir Halepovic (Somerset, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Hulya Seferoglu (Chicago, Illinois); Muhammad Usama Chaudhry (Milpitas, California); Shibin Mathew (Chicago, Illinois); Shanyu Zhou (Chicago, Illinois); Balajee Vamanan (Chicago, Illinois) |
| ABSTRACT | Concepts and technologies directed to agile transport for background traffic in cellular networks are disclosed herein. In various aspects, a system can include a processor and memory storing instructions that, upon execution, cause performance of operations. The operations can include determining a capacity of a communication path that communicatively couples a user equipment to a radio access network cell site. The operations can include identifying, from the radio access network cell site, a queue that is constructed for the user equipment. The operations can include assembling a plurality of probe burst packet sets from a background traffic flow. The operations can include probing the communication path for spare capacity using the plurality of probe burst packet sets and delivering the background traffic flow to the user equipment using the spare capacity while the communication path is not busy. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385782 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) Original (OR) Class H04L 67/28 (20130101) Wireless Communication Networks H04W 72/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848375 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Marco Platania (Maplewood, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (St. Paul, Minnesota) |
| ABSTRACT | The concepts and technologies disclosed herein are directed to a network-assisted Raft consensus protocol, referred to herein as “NetRaft.” According to one aspect of the concepts and technologies disclosed herein, a system can include a plurality of servers operating in a server cluster, and a plurality of P4 switches corresponding to the plurality of servers. Each server of the plurality of servers can include a back-end that executes a complete Raft algorithm to perform leader election, log replication, and log commitment of a Raft consensus algorithm. Each P4 switch of the plurality of P4 switches can include a front-end that executes a partial Raft algorithm to perform the log replication and the log commitment of the Raft consensus algorithm. The back-end can maintain a complete state for responding to requests that cannot be fulfilled by the front-end. The requests can include read requests and/or write requests. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/101751 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0668 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 49/355 (20130101) H04L 67/1051 (20130101) H04L 67/1093 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D902841 | Cook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Cook (Beavercreek, Ohio); Jackie Barnes (Vandalia, Ohio) |
| ABSTRACT | |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 29/646276 |
| ART UNIT | 2912 — Design |
| CURRENT CPC | Equipment for production, distribution, or transformation of energy D13/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10842373 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Wolfgang Fink (Tucson, Arizona); Mark Tarbell (Tucson, Arizona) |
| ABSTRACT | Various examples of methods, systems and devices are provided for ophthalmic examination. In one example, a handheld system includes an optical imaging assembly coupled to a user device that includes a camera aligned with optics of the optical imaging assembly. The user device can obtain ocular imaging data of at least a portion of an eye via the optics of the optical imaging assembly and provide ophthalmic evaluation results based at least in part upon the ocular imaging data. In another example, a method includes receiving ocular imaging data of at least a portion of an eye; analyzing the ocular imaging data to determine at least one ophthalmic characteristic of the eye; and determining a condition based at least in part upon the at least one ophthalmic characteristic. |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/571701 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) Original (OR) Class A61B 3/14 (20130101) A61B 3/0033 (20130101) A61B 3/0041 (20130101) A61B 3/135 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842693 | Duerstock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley S. Duerstock (West Lafayette, Indiana); Jeffrey Ackerman (Arvada, Colorado) |
| ABSTRACT | The present disclosure illustrates a motorized mount with a plurality of degrees of freedom coupled to a seating system. The motorized mount assembly can include an attachment assembly configured to attach to a seating assembly. A vertical control assembly can be connected to the attachment assembly with an arm having a first end attached to vertical control assembly by a first hinge. A mounting assembly can be attached to a second end of the arm. The mounting assembly can configured to receive a personal computing device. A linear actuator may be attached to the vertical control assembly to raise and lower the arm and mounting assembly. A first motor can be configured to attach to the arm. A second motor can be configured to attach between the arm and the mounting assembly. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 16/007638 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Chairs; Sofas; Beds A47C 7/62 (20130101) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/04 (20130101) A61G 5/08 (20130101) A61G 5/1094 (20161101) Original (OR) Class A61G 2203/16 (20130101) A61G 2203/20 (20130101) Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for B60N 3/002 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/18 (20130101) F16M 11/38 (20130101) F16M 13/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842748 | DeSimone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Agoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689733 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843139 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Shu Yang (Blue Bell, Pennsylvania); Daeyeon Lee (Wynnewood, Pennsylvania); Zhiwei Liao (Philadelphia, Pennsylvania); Gaoxiang Wu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides compositions comprising anisotropic chain-like silica nanoparticles functionalized with hydrophilic groups. The anisotropic chain-like silica nanoparticles comprise linked arrays of charged silica nanoparticles, each linked array have at least one linear dimension of from about 100 nm to about 1200 nm and the anisotropic chain-like silica nanoparticles each in have a diameter of from about 10 nm to about 500 nm. These compositions are superoleophobic in the presence of water, e.g., when submerged in water. Also provided are layered coatings comprising these compositions, substrates comprising the layered coatings, articles comprising the layered coatings, methods of filtering a mixture of water and an oil using the compositions described herein, and methods of preparing a superoleophobic coating on a substrate using the compositions described herein. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 16/312577 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/14 (20130101) B01D 65/02 (20130101) B01D 67/0041 (20130101) B01D 67/0046 (20130101) B01D 69/02 (20130101) B01D 71/027 (20130101) Original (OR) Class B01D 2311/04 (20130101) B01D 2311/04 (20130101) B01D 2311/12 (20130101) B01D 2311/12 (20130101) B01D 2311/2626 (20130101) B01D 2311/2626 (20130101) B01D 2325/36 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 1/66 (20130101) C02F 2101/32 (20130101) C02F 2101/301 (20130101) C02F 2101/325 (20130101) C02F 2103/08 (20130101) C02F 2103/10 (20130101) C02F 2303/16 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843165 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Yongsong Huang (Barrington, Rhode Island); Jose C. Aponte (Silver Spring, Maryland); Rafael Tarozo (Providence, Rhode Island); James Dillon (Pawtucket, Rhode Island) |
| ABSTRACT | Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743857 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/10 (20130101) B01D 15/38 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0233 (20130101) B01J 20/0237 (20130101) B01J 20/0262 (20130101) Original (OR) Class B01J 20/283 (20130101) B01J 20/284 (20130101) B01J 20/285 (20130101) B01J 20/287 (20130101) B01J 20/289 (20130101) B01J 20/291 (20130101) B01J 20/3204 (20130101) B01J 20/3208 (20130101) B01J 20/3219 (20130101) B01J 20/3236 (20130101) B01J 20/3242 (20130101) B01J 2220/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843189 | Hung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Paul J. Hung (Berkeley, California); Philip J. Lee (Alameda, California); Luke P. Lee (Orinda, California) |
| ABSTRACT | Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/925445 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/027 (20130101) B01L 2200/0647 (20130101) B01L 2200/0689 (20130101) B01L 2300/0627 (20130101) B01L 2300/0816 (20130101) B01L 2400/086 (20130101) B01L 2400/088 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/05 (20130101) B81B 2201/06 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/019 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 23/34 (20130101) C12M 29/06 (20130101) C12M 29/10 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843267 | Davidson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jane H. Davidson (Wayzata, Minnesota); Susan C. Mantell (Saint Paul, Minnesota); Brandon J. Hathaway (Minneapolis, Minnesota); Kunal Sudam Garde (Minneapolis, Minnesota) |
| ABSTRACT | Heat exchangers are manufactured by three-dimensional (3D) printers by printing subsequent layers of a material in a print direction. The heat exchangers include one or more tubes. The one or more tubes are configured to transport a fluid to be heated or cooled. Each of the one or more tubes defines a slope that is within a threshold angle of the print direction. The heat exchangers include a plurality of fins that are each configured to intersect with the one or more tubes while allowing fluid flow between the plurality of fins to heat or cool the fluid. Each fin of the plurality of fins defines a slope that is within a threshold angle of the print direction. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910459 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) Original (OR) Class B22F 3/1055 (20130101) B22F 3/1118 (20130101) B22F 5/10 (20130101) B22F 5/10 (20130101) B22F 5/10 (20130101) B22F 2003/1058 (20130101) B22F 2005/004 (20130101) B22F 2005/004 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/05316 (20130101) F28D 1/05333 (20130101) F28D 1/05366 (20130101) F28D 2021/0089 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/10 (20130101) F28F 1/32 (20130101) F28F 1/34 (20130101) F28F 1/40 (20130101) F28F 21/081 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844031 | Sadow et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Aaron David Sadow (Ames, Iowa); Zachary Benjamin Weinstein (Ames, Iowa); George A. Kraus (Ames, Iowa) |
| ABSTRACT | The present application relates to a process for preparation of a compound of Formula (I) and Formula (IV): wherein is as described herein; and wherein and R are as described herein. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685456 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/15 (20130101) Heterocyclic Compounds C07D 307/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844365 | Souza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Glauco R. Souza (Houston, Texas); Renata Pasqualini (Houston, Texas); Wadih Arap (Houston, Texas); Thomas Charles Killian (Houston, Texas); Robert M. Raphael (Houston, Texas); Daniel Joshua Stark (Houston, Texas) |
| ABSTRACT | Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912165 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844410 | Pfleger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Hernandez-Lozada (Madison, Wisconsin); Rung-Yi Lai (Changhua, Taiwan) |
| ABSTRACT | Mutant thioesterases having enhanced medium chain substrate activity, polynucleotides encoding and configured to express the mutant thioesterases in a transformed host cell, host cells transformed to contain the polynucleotides, and methods of using same. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357635 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845187 | Kontsos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Antonios Kontsos (Philadelphia, Pennsylvania); Fnu Melvin Domin Mathew (Philadelphia, Pennsylvania); Andrew James Ellenberg (Blackwood, New Jersey); Ivan Bartoli (Ardmore, Pennsylvania) |
| ABSTRACT | Remote measurements using images are particularly useful in structural health monitoring cases in which the installation of contact sensors is difficult. Some limitations, though, associated with photogrammetry-type optical metrology involve the application of speckle patterns, which become even more important with variable working distance or when the required resolution and sensitivity are not a priori known. In this context, multispectral sensing combined with tailored speckle patterns can circumvent some of the challenges of acquiring data at different working distances. The present invention uses multispectral imaging combined controlled generation of speckle patterns to demonstrate an approach for remote sensing related to deformation measurements at the structural level. To demonstrate this approach, two speckle patterns were designed for measurements at specified working distances. The results show that the spectral specific reflectivity of the speckle patterns allow for spatial overlay without affecting imaging within either spectral range considered, which results in the extraction of multiscale deformation measurements. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/289842 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) G01B 11/162 (20130101) Original (OR) Class G01B 11/167 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/93 (20130101) G01N 21/4788 (20130101) G01N 21/95607 (20130101) G01N 2021/479 (20130101) G01N 2021/95615 (20130101) Image Data Processing or Generation, in General G06T 7/001 (20130101) G06T 2207/10036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845324 | Kulkarni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Girish Kulkarni (Ann Arbor, Michigan); Xudong Fan (Saline, Michigan); Zhaohui Zhong (Ann Arbor, Michigan); Ayush Pandey (Ann Arbor, Michigan); Wenzhe Zang (Ann Arbor, Michigan) |
| ABSTRACT | Electrochemical sensors for the detection of select analytes are provided. The electrochemical sensors include a barrier layer having a substantially uniformed thickness disposed between a sensing layer and an ion exchange membrane. The barrier layer includes a two-dimensional nanomaterial. The barrier layer has a thickness of less than or equal to about 1 nm. The sensing layer has a thickness of less than or equal to about 10 nm. The sensing layer generates ions in response to select analytes. The barrier layer allows the generation ions to pass therethrough and travel into the ion exchange membrane. The barrier layer acts as a physical barrier to contaminants and larger molecules. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 16/071441 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3335 (20130101) Original (OR) Class G01N 27/4045 (20130101) G01N 27/4075 (20130101) G01N 33/4972 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845325 | Maboudian et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Roya Maboudian (Orinda, California); Hu Long (Albany, California); Anna Harley-Trochimczyk (Berkeley, California); William Mickelson (Albany, California); Carlo Carraro (Orinda, California) |
| ABSTRACT | A solid-state, low power microheater sensor platform that is configurable with selected metal oxide films for particular gas sensing applications is described. The sensor platform is configured by selecting a chemiresistive or catalytic material that is suitable for detecting a desired gas and then forming a porous nanostructured film on the designated surfaces of the microheater platform. Also described are methods for creating a highly porous, nanostructured metal oxide film in a controlled location from a liquid precursor using a localized heat source. By fast annealing deposited liquid precursors with the microheater, a highly porous, nanocrystalline metal oxide film can be generated in-situ and locally on the sensor platform. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045300 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 27/4067 (20130101) G01N 27/4074 (20130101) G01N 27/4075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845335 | Kurup et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Pradeep Kurup (Nashua, New Hampshire); Ramaswamy Nagarajan (Westford, Massachusetts); Timothy Ponrathnam (Lowell, Massachusetts); Weeradech Kiratitanavit (Lowell, Massachusetts) |
| ABSTRACT | An electrochemical tongue can be used for detection of metal ions. The reference electrode of the electrochemical tongue can be coated with a polymer. More than one reference electrode can be used, and the electrochemical tongue can be inserted into a cone penetrometer for portable, in situ analysis. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923698 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/48 (20130101) Original (OR) Class G01N 33/1813 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845416 | Deutsch et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Sergej Deutsch (Durham, North Carolina); Krishnendu Chakrabarty (Chapel Hill, North Carolina) |
| ABSTRACT | Embedded processor-based self-test and diagnosis using the compressed test data is described for ICs having on-chip memory. Techniques for compressing the test data before the compressed test data is transferred to a device under test (DUT) are also described. A modified LZ77 algorithm can be used to compress strings of test data in which don't care bits are handled by assigning a value to the don't care bits according to a longest match in the window as the data is being encoded. The compressed test data can be decompressed at the DUT using a software program transferred by the automated test equipment (ATE) to the DUT with the compressed test data. Decompression and diagnostics can be carried out at the DUT using an embedded processor and the on-chip memory. Results from the diagnostics can be read by the ATE. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 15/827200 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2834 (20130101) G01R 31/318547 (20130101) Original (OR) Class Electric Digital Data Processing G06F 11/263 (20130101) Static Stores G11C 5/04 (20130101) G11C 29/36 (20130101) G11C 29/40 (20130101) G11C 29/44 (20130101) G11C 29/4401 (20130101) G11C 29/56004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846251 | Caccamo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Marco Caccamo (Urbana, Illinois); Rodolfo Pellizzoni (Waterloo, Canada); Renato Mancuso (Urbana, Illinois); Rohan Tabish (Urbana, Illinois); Saud Wasly (Jeddah, Saudi Arabia) |
| ABSTRACT | An embodiment may involve determining that a first logical partition of a scratchpad memory coupled to a processor core is empty and a first application is scheduled to execute; instructing a direct memory access (DMA) engine to load the first application into the first logical partition and then instructing the processor core to execute the first application from the first logical partition; while the first application is being executed from the first logical partition, determining that a second logical partition of the scratchpad memory is empty and a second application is scheduled to execute; instructing the DMA engine to load the second application into the second logical partition; determining that execution of the first application has completed; and instructing the DMA engine to unload the first application from the first logical partition and instructing the processor core to execute the second application from the second logical partition. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/840005 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 3/061 (20130101) G06F 3/0656 (20130101) G06F 3/0683 (20130101) G06F 9/5077 (20130101) G06F 13/28 (20130101) Original (OR) Class G06F 13/1673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846356 | Gopalakrishnan et al. |
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| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Purdue University (West Lafayette, Indiana) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vijay Gopalakrishnan (Edison, New Jersey); Subhabrata Sen (Westfield, New Jersey); Shankaranarayanan Puzhavakath Narayanan (Hillsborough, New Jersey); Ashiwan Sivakumar (Pittsburgh, Pennsylvania); Sanjay Rao (West Lafayette, Indiana); Mithuna Thottethodi (West Lafayette, Indiana); Terani Vijaykumar (West Lafayette, Indiana) |
| ABSTRACT | A whittling proxy system can receive a target web page that includes a plurality of Javascript functions and a plurality of objects needed to load the target web page. The system can determine a target Javascript function of the plurality of Javascript functions to be tested for a whittling capability. The system can generate a full version and a partial version of the target web page. The full version includes all of the plurality of Javascript functions. The partial version includes the plurality of Javascript functions excluding the target Javascript function. The system can conduct a test to determine a first page signature associated with the full version and a second page signature associated with the partial version. The system can determine if the first page signature matches the second page signature, and if so, can determine that the target Javascript function can be whittled. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 16/006951 |
| ART UNIT | 2176 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9574 (20190101) Original (OR) Class G06F 40/14 (20200101) G06F 40/197 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846581 | Salman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Emre Salman (St. James, New York); Milutin Stanacevic (Smithtown, New York); Tutu Wan (Stony Brook, New York); Yasha Karimi (Selden, New York) |
| ABSTRACT | Provided is a passive charge recovery logic circuit that includes an electromagnetic field capturing device that harvests ambient electromagnetic energy, with the device including a first end and a second end; a first phase shifter including a first end connected to the first end of the device; a second phase shifter including a first end connected to the second end of the device; a peak detector including a first end connected to the first end of the device; and at least four gates that operate by respective first to fourth power clock signals. |
| FILED | Thursday, May 04, 2017 |
| APPL NO | 16/096431 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0708 (20130101) Original (OR) Class G06K 19/0723 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/02 (20130101) H02J 50/001 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846589 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| INVENTOR(S) | Ankit B. Patel (Houston, Texas); Richard G. Baraniuk (Houston, Texas) |
| ABSTRACT | A mechanism for compiling a generative description of an inference task into a neural network. First, an arbitrary generative probabilistic model from the exponential family is specified (or received). The model characterizes a conditional probability distribution for measurement data given a set of latent variables. A factor graph is generated for the generative probabilistic model. Each factor node of the factor graph is expanded into a corresponding sequence of arithmetic operations, based on a specified inference task and a kind of message passing algorithm. The factor graph and the sequences of arithmetic operations specify the structure of a neural network for performance of the inference task. A learning algorithm is executed, to determine values of parameters of the neural network. The neural network is then ready for performing inference on operational measurements. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/557793 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0472 (20130101) Original (OR) Class Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/16 (20130101) G10L 15/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846860 | Atria et al. |
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| FUNDED BY |
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| APPLICANT(S) | NVIEW MEDICAL INC. (Salt Lake City, Utah) |
| ASSIGNEE(S) | nView medical Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Cristian Atria (Salt Lake City, Utah); Arvidas B. Cheryauka (Salt Lake City, Utah); Lisa M. Last (Holladay, Utah) |
| ABSTRACT | Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469301 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 11/006 (20130101) G06T 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846928 | Alterovitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Ron Alterovitz (Chapel Hill, North Carolina); Luis Guillermo Torres (Carrboro, North Carolina); Philip Joseph Swaney (Nashville, Tennessee); Hunter Bryant Gilbert (Nashville, Tennessee); Robert James Webster (Nashville, Tennessee); Richard Joseph Hendrick (Nashville, Tennessee) |
| ABSTRACT | Systems for controlling concentric tube probes are disclosed. In some examples, the system includes a concentric tube position display interface and a control system. The concentric tube display interface includes a display for displaying visual feedback to a user indicating a position (and possibly orientation) of a tip of a concentric tube probe and a user input device for receiving user input from the user designating a goal position (and possibly orientation) for the tip of the concentric tube probe. The control system is configured for interactive-rate motion planning of the concentric tube probe by creating, in real-time or near real-time, a motion plan to move the tip of the concentric tube probe to the goal position (and possibly orientation) while avoiding contact by the concentric tube probe with one or more obstacles and for configuring the concentric tube probe as specified by the motion plan. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/576619 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/01 (20130101) A61B 1/2676 (20130101) A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2034/301 (20160201) Image Data Processing or Generation, in General G06T 19/00 (20130101) G06T 19/003 (20130101) Original (OR) Class G06T 2210/21 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847197 | Buhrman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert A. Buhrman (Ithaca, New York); Minh-hai Nguyen (Ithaca, New York); Chi-feng Pai (Ithaca, New York); Daniel C. Ralph (Ithaca, New York) |
| ABSTRACT | Devices or circuits based on spin torque transfer (STT) and Spin Hall effect are disclosed by using a spin Hall effect (SHE) metal layer coupled to a magnetic free layer for various applications. The efficiency or strength of the STT effect based on this combination of SHE and STT can be enhanced by an interface modification between the SHE metal layer and the magnetic free layer or by modifying or engineering the SHE metal layer by doping the SHE metal with certain impurities or other means. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/017565 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) G11C 11/1697 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 29/66984 (20130101) H01L 43/04 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847706 | Ivry et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts INSTITUTE of technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yachin Ivry (Brookline, Massachusetts); Jonathan J. Surick (Cambridge, Massachusetts); Karl Kimon Berggren (Arlington, Massachusetts) |
| ABSTRACT | A superconducting medium includes a first layer made of a first superconductor and a second layer made of a second superconductor. The first layer has a first thickness less than a first coherence length of the first superconductor. The second layer has a second thickness less than a second coherence length of the second superconductor so as to induce a proximity effect between the first layer and the second layer. The proximity effect can induce desirable properties in the resulting superconducting medium. Controlling the thickness ratio of the first layer to the second layer can also tune the property of the superconducting medium. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/907793 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/44 (20130101) G01J 5/10 (20130101) G01J 5/023 (20130101) G01J 5/024 (20130101) G01J 5/046 (20130101) G01J 2001/442 (20130101) G01J 2001/4446 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) Original (OR) Class H01L 39/12 (20130101) H01L 39/24 (20130101) H01L 39/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848079 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Tianwei Ma (Honolulu, Hawaii); Jian Yu (Honolulu, Hawaii); Enze Ma (Durham, North Carolina) |
| ABSTRACT | Systems, apparatuses and methods for harvesting ambient energy involve an electrically conductive charge-carrying movable electrode. An apparatus includes an electrically conductive charge-carrying electrode, a first dielectric interface region, a second dielectric interface region, and at least one reference electrode. The first and second dielectric interface regions differ in surface charge density. In certain aspects, the movable electrode moves proximate and relative to the first and second dielectric interface regions in response to receipt of ambient energy, thereby providing first and second capacitances. The first capacitance differs from the second capacitance, and/or the first surface charge density differs from the second surface charge density. Movement of the movable electrode in combination with the differing capacitances and/or charge densities results in energy accumulation, thereby enabling ambient energy to be harvested efficiently and effectively. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 16/346679 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848204 | Almasi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| ASSIGNEE(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| INVENTOR(S) | Mojtaba Ahmadi Almasi (Boise, Idaho); Hani Mehrpouyan (Boise, Idaho) |
| ABSTRACT | A system may include a radio frequency chain configured to process a signal. The system may further include a reconfigurable antenna including multiple antenna feeds, each of the antenna feeds associated with a beam direction. The system may also include a beam selection network configured to couple the radio frequency chain to a first antenna feed of the multiple antenna feeds to generate a first beam in a first direction, and simultaneously couple the radio frequency chain to a second antenna feed of the multiple antenna feeds to generate a second beam in a second direction. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209350 |
| ART UNIT | 2477 — Multiplex and VoIP |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 1/241 (20130101) Transmission H04B 7/024 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848284 | Halepovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Illinois at Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Emir Halepovic (Somerset, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Hulya Seferoglu (Chicago, Illinois); Muhammad Usama Chaudhry (Milpitas, California); Shibin Mathew (Chicago, Illinois); Shanyu Zhou (Chicago, Illinois); Balajee Vamanan (Chicago, Illinois) |
| ABSTRACT | Concepts and technologies directed to agile transport for background traffic in cellular networks are disclosed herein. In various aspects, a system can include a processor and memory storing instructions that, upon execution, cause performance of operations. The operations can include determining a capacity of a communication path that communicatively couples a user equipment to a radio access network cell site. The operations can include identifying, from the radio access network cell site, a queue that is constructed for the user equipment. The operations can include assembling a plurality of probe burst packet sets from a background traffic flow. The operations can include probing the communication path for spare capacity using the plurality of probe burst packet sets and delivering the background traffic flow to the user equipment using the spare capacity while the communication path is not busy. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385782 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) Original (OR) Class H04L 67/28 (20130101) Wireless Communication Networks H04W 72/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848303 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yuhua Chen (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Yuhua Chen (Houston, Texas) |
| ABSTRACT | Systems and methods of authenticating and/or communicating key and/or data between communication parties using quantum channels are provided. In some embodiments, authentication may be provided during transmission (including at various stages), without transmission, before transmission, and/or without keys. Such systems and methods allow authentication to be performed on a bit-by-bit basis using the same quantum communication channel. Further, these systems and methods prevent an eavesdropper from gaining useful information, and/or allow man-in-the-middle attacks to be detected. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/556152 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) H04L 9/0852 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848364 | Prothero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astrapi Corporation (Dallas, Texas) |
| ASSIGNEE(S) | Astrapi Corporation (Dallas, Texas) |
| INVENTOR(S) | Jerrold Prothero (Delray Beach, Florida); James J. Sterling (Chambersburg, Pennsylvania) |
| ABSTRACT | Systems, devices, and methods of the present invention enhance data transmission through the use of polynomial symbol waveforms (PSW) and sets of PSWs corresponding to a symbol alphabet is here termed a PSW alphabet. Methods introduced here are based on modifying polynomial alphabet by changing the polynomial coefficients or roots of PSWs and/or shaping of the polynomial alphabet to produce a designed PSW alphabet including waveforms with improved characteristics for data transmission. In various embodiments, transmitter and receivers utilizing symbol waveforms based on a PSW alphabet designed may be in wireless and/or wired data transmission systems that may or may not include transmitters and receivers employing traditional modulation formats. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/735655 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 27/363 (20130101) H04L 27/2639 (20130101) H04L 27/2647 (20130101) H04L 27/3405 (20130101) Original (OR) Class H04L 27/3494 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848375 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bo Han (Bridgewater, New Jersey); Vijay Gopalakrishnan (Edison, New Jersey); Marco Platania (Maplewood, New Jersey); Zhi-Li Zhang (Eden Prairie, Minnesota); Yang Zhang (St. Paul, Minnesota) |
| ABSTRACT | The concepts and technologies disclosed herein are directed to a network-assisted Raft consensus protocol, referred to herein as “NetRaft.” According to one aspect of the concepts and technologies disclosed herein, a system can include a plurality of servers operating in a server cluster, and a plurality of P4 switches corresponding to the plurality of servers. Each server of the plurality of servers can include a back-end that executes a complete Raft algorithm to perform leader election, log replication, and log commitment of a Raft consensus algorithm. Each P4 switch of the plurality of P4 switches can include a front-end that executes a partial Raft algorithm to perform the log replication and the log commitment of the Raft consensus algorithm. The back-end can maintain a complete state for responding to requests that cannot be fulfilled by the front-end. The requests can include read requests and/or write requests. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/101751 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0668 (20130101) Original (OR) Class H04L 45/64 (20130101) H04L 49/355 (20130101) H04L 67/1051 (20130101) H04L 67/1093 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10842388 | Dagdeviren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Canan Dagdeviren (Cambridge, Massachusetts); John A. Rogers (Urbana, Illinois); Marvin J. Slepian (Tucson, Arizona) |
| ABSTRACT | Materials and devices are provided for the sensing and manipulation of biomechanical and physiochemical properties of tissues or tissue surfaces. Examples of use include soft tissues such as skin or adipose tissues or more dense tissues such as muscle or heart or dense tissues such as bone. The materials and devices provide for in vivo measurements of biomechanical properties at the tissue surface, e.g. near surface regions of the epidermis or dermis or underlying structures. The devices can be non-invasive and/or non-destructive to the material and, especially for the biomaterials, can be biocompatible and/or biodegradable. The materials and devices can use ultrathin, stretchable networks of mechanical actuators and sensors constructed with nanoribbons of piezoelectric materials. |
| FILED | Sunday, April 17, 2016 |
| APPL NO | 15/567239 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0051 (20130101) A61B 5/0205 (20130101) Original (OR) Class A61B 5/442 (20130101) A61B 5/444 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/0261 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0492 (20130101) A61N 1/0504 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842812 | Mootha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vamsi K. Mootha (Boston, Massachusetts); Isha Jain (Cambridge, Massachusetts); Warren M. Zapol (Cambridge, Massachusetts); Luca Zazzeron (Boston, Massachusetts) |
| ABSTRACT | Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/751585 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 31/19 (20130101) A61K 31/44 (20130101) A61K 31/194 (20130101) A61K 31/198 (20130101) A61K 31/225 (20130101) A61K 31/472 (20130101) A61K 31/4704 (20130101) A61K 31/4745 (20130101) A61K 31/5377 (20130101) A61K 33/00 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) Peptides C07K 14/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/20 (20170501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/5008 (20130101) G01N 33/5041 (20130101) G01N 33/5079 (20130101) G01N 2800/04 (20130101) G01N 2800/7009 (20130101) G01N 2800/7038 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10842840 | Konowalchuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | World Force Technologies, LLC (Newport, Oregon) |
| ASSIGNEE(S) | WORLD FORCE TECHNOLOGIES, LLC (Newport, Oregon) |
| INVENTOR(S) | Thomas W. Konowalchuk (Newport, Oregon); Jack Konowalchuk (Newport, Oregon) |
| ABSTRACT | This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods of inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further includes methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses. |
| FILED | Thursday, January 24, 2019 |
| APPL NO | 16/257003 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0095 (20130101) A61K 31/353 (20130101) A61K 31/353 (20130101) A61K 31/715 (20130101) A61K 31/715 (20130101) A61K 36/87 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843154 | Burton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Patrick D. Burton (Albuquerque, New Mexico); Mark D. Tucker (Albuquerque, New Mexico); Keith E. Frakes (Albuquerque, New Mexico) |
| ABSTRACT | The present disclosure is directed to highly concentrated foam formulations for blast suppression and dispersion mitigation. for use in responding to a terrorism incident involving a blast dispersion device. The foam formulation is more concentrated and more stable than current blast suppression foams, which reduces the logistics burden on the user. |
| FILED | Monday, August 14, 2017 |
| APPL NO | 15/676628 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 17/0021 (20130101) B01F 17/0057 (20130101) B01F 17/0092 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0033 (20130101) C08J 2205/022 (20130101) C08J 2305/00 (20130101) C08J 2401/28 (20130101) Blasting F42D 5/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843261 | Balachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Uthamalingam Balachandran (Willowbrook, Illinois); Beihai Ma (Naperville, Illinois); Tae H. Lee (Naperville, Illinois); Stephen E. Dorris (LaGrange Park, Illinois); David R. Forrest (Washington, District of Columbia) |
| ABSTRACT | A method for making covetic metal-nanostructured carbon composites or compositions is described herein. This method is advantageous, in that it provides substantially oxygen-free covetic materials and allows precise control of the composition of the covetic material to be produced. The method comprises introducing carbon into a molten metal in a heated reactor under low oxygen partial pressure, while passing an electric current through the molten metal. The reactor is heated at a temperature sufficient to form a network of nanostructured carbon within a matrix of the metal. After heating the covetic material is recovered from the reactor. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/009897 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/087 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) Original (OR) Class B22F 3/1134 (20130101) B22F 2302/40 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/21 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843964 | Dai |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Steve Xunhu Dai (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to structure including an interfacial seal between a glass-ceramic component and a metal component, as well as methods for forming such structures. In particular embodiments, the interfacial seal includes a metal oxide. Such interfacial seals can be beneficial for, e.g., hermetic seals between a glass-ceramic component and a metal component. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/691948 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 37/02 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 10/0027 (20130101) C03C 10/0054 (20130101) C03C 27/042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844102 | Turley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eva A. Turley (London, Canada); Seyed Bahram Bahrami (Menlo Park, California); Mina J. Bissell (Berkeley, California) |
| ABSTRACT | Peptides that stimulate subcutaneous adipogenesis in mammals and uses thereof are provided. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 15/313538 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) A61K 8/65 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/1075 (20130101) A61K 38/00 (20130101) A61K 38/39 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/54 (20130101) A61L 2300/402 (20130101) A61L 2300/412 (20130101) A61L 2430/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) A61P 29/00 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) A61Q 19/06 (20130101) A61Q 19/08 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844231 | Monickam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | PIXELLIGENT TECHNOLOGIES, LLC (Baltimore, Maryland) |
| INVENTOR(S) | Selina Monickam (Takoma Park, Maryland); Darryl Peters (Bel Air, Maryland); Gregory Cooper (Fulton, Maryland); Zhiyun Chen (Olney, Maryland) |
| ABSTRACT | The present disclosure provides a high refractive index acrylic formulation embedded with sub-10 nm metal oxide nanocrystals. The formulation is ideal for high refractive index, high transparency coating for a variety of optical applications including OLED lighting. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/749237 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 9/04 (20130101) C08K 9/06 (20130101) C08K 2003/2244 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 3/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/00 (20130101) C09D 5/00 (20130101) C09D 5/004 (20130101) Original (OR) Class C09D 7/62 (20180101) C09D 7/67 (20180101) C09D 7/68 (20180101) C09D 7/69 (20180101) C09D 135/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0043 (20130101) H01L 51/5268 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844479 | Aytug |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Tolga Aytug (Knoxville, Tennessee) |
| ABSTRACT | An article having a nanostructured surface and a method of making the same are described. The article can include a substrate and a nanostructured layer bonded to the substrate. The nanostructured layer can include a plurality of spaced apart nanostructured features comprising a contiguous, protrusive material and the nanostructured features can be sufficiently small that the nanostructured layer is optically transparent. A surface of the nanostructured features can be coated with a continuous hydrophobic coating. The method can include providing a substrate; depositing a film on the substrate; decomposing the film to form a decomposed film; and etching the decomposed film to form the nanostructured layer. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 15/843471 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 11/005 (20130101) C03C 17/008 (20130101) C03C 2217/47 (20130101) C03C 2217/425 (20130101) C03C 2217/452 (20130101) C03C 2218/33 (20130101) C03C 2218/154 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/10 (20130101) C23C 14/35 (20130101) C23C 14/5806 (20130101) C23C 14/5873 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/249969 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844497 | Beachy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | pH Matter, LLC (Columbus, Ohio) |
| ASSIGNEE(S) | Power to Hydrogen, LLC (Columbus, Ohio) |
| INVENTOR(S) | Michael G. Beachy (Gahana, Ohio); Christopher T. Holt (Bexley, Ohio); Minette Ocampo (Columbus, Ohio); Paul H. Matter (Columbus, Ohio) |
| ABSTRACT | A novel electrochemical cell is disclosed in multiple embodiments. The instant invention relates to an electrochemical cell design. In one embodiment, the cell design can electrolyze water into pressurized hydrogen using low-cost materials. In another embodiment, the cell design can convert hydrogen and oxygen into electricity. In another embodiment, the cell design can electrolyze water into hydrogen and oxygen for storage, then later convert the stored hydrogen and oxygen back into electricity and water. |
| FILED | Thursday, April 19, 2018 |
| APPL NO | 15/957052 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/10 (20130101) C25B 9/08 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8668 (20130101) H01M 8/083 (20130101) H01M 8/186 (20130101) H01M 8/0289 (20130101) H01M 8/2455 (20130101) H01M 8/2459 (20160201) H01M 8/2483 (20160201) H01M 2300/0014 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844501 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
| INVENTOR(S) | Di-Jia Liu (Elmhurst, Illinois); Tao Xu (Naperville, Illinois); Dominic Rebollar (New Lenox, Illinois); Haiping Xu (Dekalb, Illinois) |
| ABSTRACT | Electrocatalysts composed of single atoms dispersed over porous carbon support were prepared by a lithium-melt method. The new catalysts demonstrated high selectivity, high Faradic efficiency and low overpotential toward to the electrocatalytic reduction of carbon dioxide to fuels. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915259 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/087 (20130101) B01J 2219/0803 (20130101) B01J 2219/0875 (20130101) B01J 2219/0892 (20130101) Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) C07C 29/154 (20130101) C07C 29/158 (20130101) C07C 45/00 (20130101) C07C 51/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) C25B 11/035 (20130101) C25B 11/0405 (20130101) C25B 11/0478 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844507 | Bunn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Thomas L. Bunn (Livermore, California); Corie Horwood (Livermore, California) |
| ABSTRACT | The present disclosure relates to an apparatus for electroplating an element. The apparatus may comprise a cathode cage assembly. The cathode cage assembly may include a cage member and at least one electrically conductive wire extending along at least a portion of the cage member. The wire may be arranged to form at least one volume within the cage member for retaining an element within the cage member. The cage member and the wire permit a degree of movement of the element during an electroplating process while retaining the element within the volume. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/965317 |
| ART UNIT | 1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/20 (20130101) C25D 7/00 (20130101) C25D 17/08 (20130101) C25D 17/12 (20130101) Original (OR) Class C25D 21/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844658 | Wheeler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Lance Michael Wheeler (Wheat Ridge, Colorado); Joseph Matthew Luther (Boulder, Colorado); Jeffrey A. Christians (Denver, Colorado); Joseph Jonathan Berry (Boulder, Colorado) |
| ABSTRACT | The present disclosure relates to devices that include a perovskite, where, when a first condition is met, at least a portion of the perovskite is in a first phase that substantially transmits light, when a second condition is met, at least a portion of the perovskite is in a second phase that substantially absorbs light, and the perovskite is reversibly switchable between the first phase and the second phase by reversibly switching between the first condition and the second condition. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906696 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) Original (OR) Class E06B 2009/2417 (20130101) E06B 2009/2476 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0147 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/4226 (20130101) H01L 51/4253 (20130101) H01L 2251/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845067 | Martin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Energy and Enviornmental Research Center (Grand Forks, North Dakota) |
| INVENTOR(S) | Christopher Lee Martin (Grand Forks, North Dakota) |
| ABSTRACT | In various embodiments, the present invention relates to heat dissipation systems including a hygroscopic working fluid integrating waste water as makeup water. The present invention also relates to methods of using the same. The present invention also relates to hygroscopic cooling systems adapted to dispose of waste water by combining the waste water with a hygroscopic working fluid, precipitating impurities and evaporating the remaining water. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/918916 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 9/003 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 5/0035 (20130101) F24F 2003/144 (20130101) Steam or Vapour Condensers F28B 9/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/02 (20130101) F28C 1/04 (20130101) F28C 1/16 (20130101) F28C 2001/006 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 23/02 (20130101) F28F 25/02 (20130101) F28F 25/12 (20130101) F28F 25/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845302 | Mallery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
| ASSIGNEE(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
| INVENTOR(S) | Ryan Mallery (Houston, Texas); Ohad Israel Balila (Friendswood, Texas); Robert Timothy Kester (Friendswood, Texas) |
| ABSTRACT | An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/664615 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/314 (20130101) G01N 21/3504 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845325 | Maboudian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Roya Maboudian (Orinda, California); Hu Long (Albany, California); Anna Harley-Trochimczyk (Berkeley, California); William Mickelson (Albany, California); Carlo Carraro (Orinda, California) |
| ABSTRACT | A solid-state, low power microheater sensor platform that is configurable with selected metal oxide films for particular gas sensing applications is described. The sensor platform is configured by selecting a chemiresistive or catalytic material that is suitable for detecting a desired gas and then forming a porous nanostructured film on the designated surfaces of the microheater platform. Also described are methods for creating a highly porous, nanostructured metal oxide film in a controlled location from a liquid precursor using a localized heat source. By fast annealing deposited liquid precursors with the microheater, a highly porous, nanocrystalline metal oxide film can be generated in-situ and locally on the sensor platform. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045300 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 27/4067 (20130101) G01N 27/4074 (20130101) G01N 27/4075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10845608 | Froula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Dustin H. Froula (Rochester, New York); Terrance Kessler (Rochester, New York) |
| ABSTRACT | Methods and systems are disclosed for using a chromatic lens system to provide a “flying focus”—i.e., an advanced focusing scheme enabling spatiotemporal control of a focal location. In a method, a photon beam is emitted from a source at a wavelength. The photon beam may have more than one wavelength. The photon beam is focused to a focal location using a chromatic lens system. The focal location is at a first longitudinal distance along an optical axis from the chromatic lens system. The wavelength of the photon beam is changed as a function of time to change the focal location as a function of time. The wavelength may be changed such that the focal location changes with a focal velocity. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 15/784789 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1814 (20130101) G02B 5/1866 (20130101) G02B 5/1876 (20130101) G02B 27/40 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847271 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Michael William Donald Cooper (Los Alamos, New Mexico); Anders David Ragnar Andersson (Los Alamos, New Mexico); Christopher Richard Stanek (Los Alamos, New Mexico) |
| ABSTRACT | A nuclear fuel includes uranium(IV) oxide (UO2) and manganese (Mn) as a dopant. The Mn dopant may be present in the fuel in an amount up to the solubility limit for Mn under a given set of conditions, for example, about 0.01 wt % to about 1 wt %. The nuclear fuel is substantially free of aluminum (Al). The nuclear fuel exhibits enhanced grain size development during sintering temperatures as low at 1400 K due to an increase in uranium sub-lattice vacancies induced by dissolution of the Mn dopant at interstitial defect sites. The Mn-doped nuclear fuel exhibits improved grain sizes at lower temperatures compared to Cr-, Al-, and undoped UO2, and therefore desirably exhibits lower fission gas release and higher plasticity, reducing the chances of fuel rod failure. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/101808 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/51 (20130101) C04B 35/64 (20130101) C04B 2111/00862 (20130101) C04B 2235/40 (20130101) Nuclear Reactors G21C 3/60 (20130101) G21C 3/623 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847272 | Lobscheid |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Christian Lobscheid (Corvallis, Oregon) |
| ABSTRACT | The drive assembly includes annular drive magnets extending around a top end of a drive shaft and annular drive coils extending around the drive magnets, separated by a pressure boundary. A latch assembly is coupled to the drive magnets and engages with the drive shaft in response to actuation of the drive assembly. The drive coils also rotate the drive magnets and the engaged latch assembly to axially displace the drive shaft. Deactivating the drive coils disengages the latch assembly from the drive shaft, dropping a connected control rod assembly via gravity into a nuclear fuel assembly. |
| FILED | Friday, December 29, 2017 |
| APPL NO | 15/858727 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 1/32 (20130101) G21C 7/14 (20130101) Original (OR) Class G21C 7/117 (20130101) G21C 9/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/39 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847738 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kai Zhu (Littleton, Colorado); Zhiwen Ma (Golden, Colorado); John Mehmet Dagdelen (Alameda, California) |
| ABSTRACT | An aspect of the present disclosure is a method that includes, in a first mixture that includes a metal alkoxide and water, reacting at least a portion of the metal alkoxide and at least a portion of the water to form a second mixture that includes a solid metal oxide phase dispersed in the second mixture, applying the second mixture onto a surface of a device that includes an intervening layer adjacent to a perovskite layer such that the intervening layer is between the second mixture and perovskite layer, and treating the second mixture, such that the solid metal oxide phase is transformed to a first solid metal oxide layer such that the intervening layer is positioned between the first solid metal oxide layer and the perovskite layer. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487988 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2077 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/448 (20130101) Original (OR) Class H01L 51/4226 (20130101) H01L 2251/306 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847805 | Sakamoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Jeffrey Sakamoto (Ann Arbor, Michigan); Travis Thompson (Ann Arbor, Michigan); Nathan Taylor (Ann Arbor, Michigan) |
| ABSTRACT | An article for forming an electrochemical device is disclosed. The article comprises a metallic current collector clad with an ion conducting solid-electrolyte material such that intimate contact between the current collector and the ion conducting solid-electrolyte material is made. A lithium metal anode can be formed in situ between the current collector clad and the ion conducting solid-electrolyte material from lithium ions contained within a cathode material that is placed in contact with the ion conducting solid-electrolyte material. A bipolar electrochemical cell can be constructed from the article. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243525 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/382 (20130101) H01M 4/485 (20130101) H01M 4/582 (20130101) H01M 4/661 (20130101) H01M 4/662 (20130101) H01M 4/667 (20130101) Original (OR) Class H01M 4/5815 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/0585 (20130101) H01M 2004/028 (20130101) H01M 2300/0071 (20130101) H01M 2300/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847829 | Huskinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Brian Huskinson (Flower Mound, Texas); Michael Marshak (Cambridge, Massachusetts); Michael J. Aziz (Concord, Massachusetts); Roy G. Gordon (Cambridge, Massachusetts); Alan Aspuru-Guzik (Cambridge, Massachusetts); Suleyman Er (Katwijk, Netherlands); Changwon Suh (Centreville, Virginia); Liuchuan Tong (Cambridge, Massachusetts); Kaixiang Lin (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides an electrochemical cell based on a new chemistry for a flow battery for large scale, e.g., gridscale, electrical energy storage. Electrical energy is stored chemically in quinone molecules having multiple oxidation states, e.g., three or more. During charging of the battery, the quinone molecules at one electrode are oxidized by emitting electrons and protons, and the quinone molecules at the other electrode are reduced by accepting electrons and protons. These reactions are reversed to deliver electrical energy. The invention also provides additional high and low potential quinones that are useful in rechargeable batteries. |
| FILED | Friday, September 26, 2014 |
| APPL NO | 15/025040 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/2528 (20190201) B29C 48/2886 (20190201) B29C 64/393 (20170801) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 2250/10 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/14 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847839 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chi Cheung Su (Westmont, Illinois); Khalil Amine (Oakbrook, Illinois); Meinan He (Willowbrook, Illinois) |
| ABSTRACT | An electrochemical cell includes a cathode active material, lithium metal, a separator, and an electrolyte comprising a lithium salt, an organic aprotic solvent and a fluorinated sulfone represented by Formula II: |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052425 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0034 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847840 | Liao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chen Liao (Westmont, Illinois); Ilya A. Shkrob (Chicago, Illinois); Daniel Abraham (Bolingbrook, Illinois); Zhengcheng Zhang (Naperville, Illinois) |
| ABSTRACT | Lithium tetrafluoro(malonato)phosphate compounds are useful as additives in lithium ion battery applications. The compounds are represented by Formula (I): MPF4[—O(C═O)—(CX′X″)—(C═O)O—]; wherein M is Li or Na; each X′ and X″ independently is selected from the group consisting of H, alkyl, fluoro-substituted alkyl, and F; or wherein the X′ and X″ together are —CR2—(CR′2)m—CR″2—; each R, R′ and R″ independently is selected from the group consisting of H, methyl, trifluoromethyl, and F; and m is 0 or 1. These compounds can be prepared in high purity and a high yield by reaction of a metal hexafluorophosphate with a bis-silyl malonate compound. A similar oxalato compound, lithium tetrafluoro(oxalato)phosphate), can be made in the same manner, but using a bis-silyl oxalate in place of the bis-silyl malonate. Advantageously, the compounds can be formed, in situ, in a LiPF6-containing electrolyte solution. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175497 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/587 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848481 | Cebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mumin Cebe (Miami, Florida); Kemal Akkaya (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Mumin Cebe (Miami, Florida); Kemal Akkaya (Miami, Florida) |
| ABSTRACT | Systems and methods for certificate revocation management for advanced metering infrastructure networks are provided. An accumulation manager can be used to accumulate certificate revocation list (CRL) information and determine an accumulator value and a proof value based on the accumulated CRL information using a plurality of functions. These values can be sent on to smart meters, which can then use them for authentication purposes. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875050 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/20 (20130101) H04L 63/0823 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10843041 | Cobb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tyson Cobb (Pensacola, Florida); Travis Craig (Pensacola, Florida); Jeremy Gines (Pensacola, Florida); Peter Neuhaus (Pensacola, Florida) |
| ASSIGNEE(S) | Florida Institute for Human and Machine Cognition, Inc. (Pensacola, Florida) |
| INVENTOR(S) | Tyson Cobb (Pensacola, Florida); Travis Craig (Pensacola, Florida); Jeremy Gines (Pensacola, Florida); Peter Neuhaus (Pensacola, Florida) |
| ABSTRACT | An exercise device where force is applied by computer-controlled actuators. The programmable nature of the force application allows the device to simulate weight-training devices and other useful exercise devices. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/421780 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/023 (20130101) A63B 21/156 (20130101) A63B 21/0428 (20130101) A63B 21/4033 (20151001) A63B 23/1281 (20130101) A63B 23/03525 (20130101) A63B 24/0062 (20130101) A63B 24/0087 (20130101) Original (OR) Class A63B 2024/0093 (20130101) A63B 2220/51 (20130101) A63B 2220/54 (20130101) A63B 2220/833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843165 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Yongsong Huang (Barrington, Rhode Island); Jose C. Aponte (Silver Spring, Maryland); Rafael Tarozo (Providence, Rhode Island); James Dillon (Pawtucket, Rhode Island) |
| ABSTRACT | Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743857 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/10 (20130101) B01D 15/38 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0233 (20130101) B01J 20/0237 (20130101) B01J 20/0262 (20130101) Original (OR) Class B01J 20/283 (20130101) B01J 20/284 (20130101) B01J 20/285 (20130101) B01J 20/287 (20130101) B01J 20/289 (20130101) B01J 20/291 (20130101) B01J 20/3204 (20130101) B01J 20/3208 (20130101) B01J 20/3219 (20130101) B01J 20/3236 (20130101) B01J 20/3242 (20130101) B01J 2220/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10843240 | Rangan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MATERIALS MODIFICATION INC. (Fairfax, Virginia) |
| ASSIGNEE(S) | MATERIALS MODIFICATION INC. (Fairfax, Virginia) |
| INVENTOR(S) | Krishnaswamy Kasthuri Rangan (Fairfax, Virginia); Tirumalai Srinivas Sudarshan (Vienna, Virginia) |
| ABSTRACT | Disclosure of a container to store solid and liquid wastes and perishable goods and protect them from microbial damage. The storage container is also amenable to selectively remove water vapor from inside the bag without damaging the container. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905700 |
| ART UNIT | 1799 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/04 (20130101) A61L 2/18 (20130101) A61L 11/00 (20130101) Disposal of Solid Waste B09B 3/0025 (20130101) B09B 3/0083 (20130101) Original (OR) Class Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 33/00 (20130101) B65D 81/18 (20130101) B65D 81/28 (20130101) B65D 81/34 (20130101) Gathering or Removal of Domestic or Like Refuse B65F 1/0006 (20130101) B65F 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846873 | Versace et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Neurala, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Neurala, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Massimiliano Versace (Boston, Massachusetts); Anatoly Gorshechnikov (Newton, Massachusetts) |
| ABSTRACT | Sensory processing of visual, auditory, and other sensor information (e.g., visual imagery, LIDAR, RADAR) is conventionally based on “stovepiped,” or isolated processing, with little interactions between modules. Biological systems, on the other hand, fuse multi-sensory information to identify nearby objects of interest more quickly, more efficiently, and with higher signal-to-noise ratios. Similarly, examples of the OpenSense technology disclosed herein use neurally inspired processing to identify and locate objects in a robot's environment. This enables the robot to navigate its environment more quickly and with lower computational and power requirements. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139466 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) G01S 7/41 (20130101) G01S 13/86 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/629 (20130101) G06K 9/00664 (20130101) G06K 9/3241 (20130101) G06K 9/4628 (20130101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) G06N 3/049 (20130101) G06N 3/0409 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847023 | Jessop |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Metis Technology Solutions, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | METIS TECHNOLOGY SOLUTIONS, INC. (Albuquerque, New Mexico) |
| INVENTOR(S) | Richard Karle Jessop (Williamsburg, Virginia) |
| ABSTRACT | An information processing system for monitoring a system. An embodiment of the present invention is a system (and concomitant methods and computer software embodied in non-transitory computer readable media) providing prioritized information and several extensions. These extensions include improved information flow between actors that participate in monitoring the system. These actors each have a model of its environment and may include either human operators, computational or software systems, or hardware systems that can act on information; for example, a pilot flying, a pilot monitoring, an aircraft itself, and responses taken and electronics readings therein. Components of the system comprise a metadata workbench, an information source, a condition monitor, and a notification terminal. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/442059 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/02 (20130101) G08B 21/18 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101) Original (OR) Class Broadcast Communication H04H 60/73 (20130101) Pictorial Communication, e.g Television H04N 1/00137 (20130101) H04N 21/84 (20130101) Selecting H04Q 9/00 (20130101) H04Q 2209/00 (20130101) H04Q 2209/30 (20130101) H04Q 2209/40 (20130101) H04Q 2209/70 (20130101) H04Q 2209/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10847419 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Scott S. Miller (Waltham, Massachusetts); Christine Frandsen (Waltham, Massachusetts); Andrew Cahill (Waltham, Massachusetts); Sean P. Kilcoyne (Waltham, Massachusetts); Shannon Wilkey (Waltham, Massachusetts) |
| ABSTRACT | Disclosed is a process for manufacturing individual die devices, with a desired or predicted amount of flatness, from a bonded wafer process. The flatness of a bonded wafer is measured at point in the wafer manufacturing process. This measurement is compared to a value predetermined by an empirical analysis of previous devices made by the same process. If the flatness of the bonded wafer is not at the predetermined value, then one or more compensation layers are provided to the bonded wafer to obtain the predetermined flatness value. Once obtained, subsequent processing is performed and the resulting individual dies are obtained with the desired flatness characteristic. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 15/920983 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) Original (OR) Class H01L 21/6835 (20130101) H01L 22/12 (20130101) H01L 22/20 (20130101) H01L 23/562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848989 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/724038 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10848990 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/724047 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10843240 | Rangan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MATERIALS MODIFICATION INC. (Fairfax, Virginia) |
| ASSIGNEE(S) | MATERIALS MODIFICATION INC. (Fairfax, Virginia) |
| INVENTOR(S) | Krishnaswamy Kasthuri Rangan (Fairfax, Virginia); Tirumalai Srinivas Sudarshan (Vienna, Virginia) |
| ABSTRACT | Disclosure of a container to store solid and liquid wastes and perishable goods and protect them from microbial damage. The storage container is also amenable to selectively remove water vapor from inside the bag without damaging the container. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905700 |
| ART UNIT | 1799 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/04 (20130101) A61L 2/18 (20130101) A61L 11/00 (20130101) Disposal of Solid Waste B09B 3/0025 (20130101) B09B 3/0083 (20130101) Original (OR) Class Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 33/00 (20130101) B65D 81/18 (20130101) B65D 81/28 (20130101) B65D 81/34 (20130101) Gathering or Removal of Domestic or Like Refuse B65F 1/0006 (20130101) B65F 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844231 | Monickam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | PIXELLIGENT TECHNOLOGIES, LLC (Baltimore, Maryland) |
| INVENTOR(S) | Selina Monickam (Takoma Park, Maryland); Darryl Peters (Bel Air, Maryland); Gregory Cooper (Fulton, Maryland); Zhiyun Chen (Olney, Maryland) |
| ABSTRACT | The present disclosure provides a high refractive index acrylic formulation embedded with sub-10 nm metal oxide nanocrystals. The formulation is ideal for high refractive index, high transparency coating for a variety of optical applications including OLED lighting. |
| FILED | Wednesday, July 27, 2016 |
| APPL NO | 15/749237 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 9/04 (20130101) C08K 9/06 (20130101) C08K 2003/2244 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 3/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/00 (20130101) C09D 5/00 (20130101) C09D 5/004 (20130101) Original (OR) Class C09D 7/62 (20180101) C09D 7/67 (20180101) C09D 7/68 (20180101) C09D 7/69 (20180101) C09D 135/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0043 (20130101) H01L 51/5268 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846860 | Atria et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIEW MEDICAL INC. (Salt Lake City, Utah) |
| ASSIGNEE(S) | nView medical Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Cristian Atria (Salt Lake City, Utah); Arvidas B. Cheryauka (Salt Lake City, Utah); Lisa M. Last (Holladay, Utah) |
| ABSTRACT | Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469301 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 11/006 (20130101) G06T 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10846873 | Versace et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Neurala, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Neurala, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Massimiliano Versace (Boston, Massachusetts); Anatoly Gorshechnikov (Newton, Massachusetts) |
| ABSTRACT | Sensory processing of visual, auditory, and other sensor information (e.g., visual imagery, LIDAR, RADAR) is conventionally based on “stovepiped,” or isolated processing, with little interactions between modules. Biological systems, on the other hand, fuse multi-sensory information to identify nearby objects of interest more quickly, more efficiently, and with higher signal-to-noise ratios. Similarly, examples of the OpenSense technology disclosed herein use neurally inspired processing to identify and locate objects in a robot's environment. This enables the robot to navigate its environment more quickly and with lower computational and power requirements. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/139466 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/16 (20130101) G01S 7/41 (20130101) G01S 13/86 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/629 (20130101) G06K 9/00664 (20130101) G06K 9/3241 (20130101) G06K 9/4628 (20130101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) G06N 3/049 (20130101) G06N 3/0409 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10844224 | Tisserat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Brent Tisserat (Washington, Illinois) |
| ABSTRACT | A method for producing an engineered wood material may include a matrix material and filler material. In some embodiments, a separate binder and/or adhesive is not required. The matrix and filler materials may be bio-based and/or renewable materials. The engineered wood material may be produced by compressing the mixed components together under pressure at an elevated temperature for a predetermined amount of time. An advantage of the present invention may be that such materials are easily and cheaply replenished, as opposed to non-bio-based materials which include petroleum-based or other non-renewable products in their manufacture. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651149 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/16 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) C08L 91/00 (20130101) C08L 91/00 (20130101) C08L 97/02 (20130101) Original (OR) Class C08L 97/02 (20130101) C08L 97/005 (20130101) C08L 101/16 (20130101) C08L 2201/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10844315 | Harry-O'Kuru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Rogers E. Harry-O'Kuru (Peoria, Maryland); Girma Biresaw (Peoria, Illinois); Rex E. Murray (Peoria, Illinois) |
| ABSTRACT | Disclosed herein are polyketone triglyceride compositions containing 8 to 16 ketone carbonyl moieties per triglyceride unit and methods of making. Also disclosed are polyimine triglyceride compositions having has 8 to 16 nitrogen moieties per triglyceride unit and methods of making. Also disclosed are polyamine triglyceride compositions containing 8 to 16 nitrogen moieties per triglyceride unit and methods of making. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/554796 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/716 (20130101) C07C 219/06 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 105/20 (20130101) C10M 105/56 (20130101) C10M 105/60 (20130101) C10M 129/95 (20130101) C10M 133/06 (20130101) C10M 133/22 (20130101) C10M 159/12 (20130101) C10M 177/00 (20130101) Original (OR) Class C10M 2207/34 (20130101) C10M 2207/40 (20130101) C10M 2207/401 (20130101) C10M 2215/003 (20130101) C10M 2215/04 (20130101) C10M 2215/14 (20130101) C10M 2215/041 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2030/02 (20130101) C10N 2030/06 (20130101) C10N 2030/14 (20130101) C10N 2060/02 (20130101) C10N 2060/04 (20130101) C10N 2070/00 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10842849 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 14/002033 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 9/0085 (20130101) A61K 9/5169 (20130101) A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 35/30 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/30 (20130101) A61K 38/1703 (20130101) A61K 38/1709 (20130101) A61K 38/1738 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 49/0056 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 2501/105 (20130101) C12N 2502/08 (20130101) C12N 2502/081 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/5073 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D902790 | Nowak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Vikki Nowak (Cleveland Heights, Ohio); Rebecca Lynn Blice (Akron, Ohio); Shawn Dellinger (Cleveland, Ohio); Maynard Payumo (Parma, Ohio); Ronald J. Triolo (Cleveland Heights, Ohio); Stephanie Bailey (Shaker Heights, Ohio); Kevin Foglyano (Lakewood, Ohio); Lisa M. Lombardo (Chardon, Ohio) |
| ABSTRACT | |
| FILED | Monday, August 06, 2018 |
| APPL NO | 29/659034 |
| ART UNIT | 2918 — Design |
| CURRENT CPC | Transportation D12/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10842571 | Hoffman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Brian D. Hoffman (Mountain View, California); David Q. Larkin (Menlo Park, California); Giuseppe Maria Prisco (Calci, Italy); Guanghua G. Zhang (San Jose, California); Rajesh Kumar (Sunnyvale, California) |
| ABSTRACT | Methods and system perform tool tracking during minimally invasive robotic surgery. Tool states are determined using triangulation techniques or a Bayesian filter from either or both non-endoscopically derived and endoscopically derived tool state information, or from either or both non-visually derived and visually derived tool state information. The non-endoscopically derived tool state information is derived from sensor data provided either by sensors associated with a mechanism for manipulating the tool, or sensors capable of detecting identifiable signals emanating or reflecting from the tool and indicative of its position, or external cameras viewing an end of the tool extending out of the body. The endoscopically derived tool state information is derived from image data provided by an endoscope inserted in the body so as to view the tool. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650804 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/00193 (20130101) A61B 1/3132 (20130101) A61B 5/06 (20130101) A61B 5/061 (20130101) A61B 5/062 (20130101) A61B 5/725 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 34/30 (20160201) A61B 34/37 (20160201) A61B 90/36 (20160201) A61B 90/39 (20160201) A61B 90/361 (20160201) A61B 2034/102 (20160201) A61B 2034/2065 (20160201) A61B 2090/364 (20160201) A61B 2090/0818 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10845277 | Packingham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | InnovaPrep LLC (Drexel, Missouri) |
| ASSIGNEE(S) | INNOVAPREP, LLC (Drexel, Missouri) |
| INVENTOR(S) | Zachary Allen Packingham (Drexel, Missouri); Andrew Edward Page (Smithton, Missouri); David Scott Alburty (Drexel, Missouri); Steven Dale Graham (Overland Park, Kansas); Alec Douglas Adolphson (Raymore, Missouri) |
| ABSTRACT | The present disclosure provides for devices, systems and methods for fractionation and concentration of particles from a fluid sample. This includes a cartridge containing staged filters having porous surface in series of decreasing pore size for capture of particles from a fluid sample; and a permeate pressure source in fluid communication with the cartridge; wherein the particles are eluted from the porous surfaces and dispensed in a reduced fluid volume. |
| FILED | Friday, October 18, 2013 |
| APPL NO | 14/058193 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/20 (20130101) B01D 61/22 (20130101) B01D 63/082 (20130101) B01D 63/088 (20130101) B01D 2315/08 (20130101) B01D 2319/06 (20130101) B01D 2321/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 1/405 (20130101) Original (OR) Class G01N 1/4055 (20130101) G01N 1/4077 (20130101) G01N 2001/4016 (20130101) G01N 2001/4038 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10848079 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Tianwei Ma (Honolulu, Hawaii); Jian Yu (Honolulu, Hawaii); Enze Ma (Durham, North Carolina) |
| ABSTRACT | Systems, apparatuses and methods for harvesting ambient energy involve an electrically conductive charge-carrying movable electrode. An apparatus includes an electrically conductive charge-carrying electrode, a first dielectric interface region, a second dielectric interface region, and at least one reference electrode. The first and second dielectric interface regions differ in surface charge density. In certain aspects, the movable electrode moves proximate and relative to the first and second dielectric interface regions in response to receipt of ambient energy, thereby providing first and second capacitances. The first capacitance differs from the second capacitance, and/or the first surface charge density differs from the second surface charge density. Movement of the movable electrode in combination with the differing capacitances and/or charge densities results in energy accumulation, thereby enabling ambient energy to be harvested efficiently and effectively. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 16/346679 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10845288 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Daren Chen (Glen Allen, Virginia); Qiaoling Liu (Richmond, Virginia) |
| ABSTRACT | A particle electrical mobility classifier is provided for the classification of particles (e.g., particles less than 1 μιη in size) based on their electrical mobility. The particle classification zone is curved. In an exemplary embodiment, two metal concentric cylinders, separated by an annular insulation spacer, establish a particle classification zone. A DC electrical field is supplied by the cylinders in the circular classification zone. An example classifier can be operated in different modes such as: (1) as a particle precipitator; (2) as a particle electrical mobility separator, and (3) as a differential mobility classifier. The curved classification zone results in a particle classifier having an extended particle sizing range as compared to their counterparts in classical configurations. The curve of the classification channel (in the flow direction) may be in any of several configurations (e.g., circular, wavy, spiral, or helical). |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/768574 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 3/15 (20130101) B03C 3/36 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0266 (20130101) Original (OR) Class G01N 2015/0038 (20130101) G01N 2015/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10846296 | Strachan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | John Paul Strachan (San Carlos, California); Catherine Graves (Palo Alto, California) |
| ABSTRACT | Filters are represented as k-SAT solutions. A filter query includes a k-SAT clause having literals pertaining to variables. A ternary content-addressable memory (TCAM) has cells programmed in correspondence with the k-SAT solutions. Input column lines of the TCAM that correspond to variables to which the literals of the k-SAT clause pertain are set in accordance with inversions of the literals. Input column lines of the TCAM that correspond to variables to which no literal of the k-SAT clause pertains are set in accordance with a “don't care” state. Responsive to any output match row line of the TCAM being set, the filter query is indicated as failing to satisfy the filters. Responsive to no output match row line of the TCAM being set, the filter query is indicated as satisfying the filters. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966817 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2468 (20190101) Original (OR) Class G06F 21/552 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 24, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201124.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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