FedInvent™ Patents

Patent Details for Tuesday, December 01, 2020 

This page was updated on Monday, March 27, 2023 at 06:14 AM GMT

Department of Health and Human Services (HHS) 

US 10849492 Tomasi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Matteo Tomasi (Boston, Massachusetts);  Shrinivas Pundlik (Boston, Massachusetts);  Kevin Edward Houston (Norwell, Massachusetts);  Gang Luo (Lexington, Massachusetts)
ABSTRACT Disclosed are a mobile device and method which include acquiring, by an image acquisition unit installed in a mobile device, an image of eyes of a patient while light provided by a light source reflects from an optical surface of the eyes of the patient; and obtaining, by a processor installed in the mobile device, ocular misalignment measurements, including a magnitude and a direction of ocular misalignment in the eyes of the patient, using the acquired image or set of images.
FILED Thursday, February 16, 2017
APPL NO 16/076592
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/00 (20130101)
A61B 3/08 (20130101)
A61B 3/10 (20130101)
A61B 3/14 (20130101)
A61B 3/085 (20130101) Original (OR) Class
A61B 3/152 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/22 (20130101)
G06K 9/0061 (20130101)
G06K 9/209 (20130101)
G06K 9/00604 (20130101)
G06K 9/00912 (20130101)
G06K 9/2027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849519 Mendenhall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  UPMC (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) George Stuart Mendenhall (Pittsburgh, Pennsylvania);  Matthew Jones (Pittsburgh, Pennsylvania)
ABSTRACT Disclosed are wearable devices, such as rings and bracelets, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms and methods. The disclosed wearable devices can continuously monitor the wearer's cardiovascular status by measuring heart rate, motion, blood oxygenation, and/or other properties of the wearer. Disclosed wearable devices can further comprise three EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger/wrist, a second electrode on the outer surface adapted to detect a cardiovascular signal from a finger of the opposing hand, and a third electrode on the outer surface of the frame adapted to detect a cardiovascular signal from a EKG lead location on the wearer's chest or leg. The wearable devices can be linked wirelessly to a mobile device that the person can interact with, and can further be linked to other distributed system components and healthcare providers.
FILED Thursday, March 31, 2016
APPL NO 15/560297
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/11 (20130101)
A61B 5/0022 (20130101)
A61B 5/0205 (20130101)
A61B 5/0408 (20130101) Original (OR) Class
A61B 5/0452 (20130101)
A61B 5/0488 (20130101)
A61B 5/683 (20130101)
A61B 5/02438 (20130101)
A61B 5/6826 (20130101)
A61B 5/7275 (20130101)
A61B 5/14552 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/048 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/67 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849561 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Virginia Patent Foundation (Charlotlesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Wei Huang (Charlottesville, Virginia);  Yang Yang (Charlottesville, Virginia);  Xiao Chen (Charlottesville, Virginia);  Michael Salerno (Charlottesville, Virginia)
ABSTRACT In some aspects, the disclosed technology relates to reducing respiratory-induced motion artifacts for accelerated imaging. In one embodiment, magnetic resonance data may be acquired for an area of a subject containing the heart. The acquired data may include motion-corrupted data due to respiration of the subject. From the acquired data, an image may be independently reconstructed for each of a plurality of time frames, with each time frame corresponding to one of a plurality of heartbeats. A region containing the heart of the subject may be automatically detected in the reconstructed images, and rigid motion registration may be performed on the region of the reconstructed images containing the heart. Based on the rigid motion registration, a linear phase shift for motion correction may be determined. The linear phase shift may be applied to the motion-corrupted data to produce linear phase-shifted data, and a k-t image reconstruction may be performed on the linear phase-shifted data to produce motion-corrected images.
FILED Friday, October 21, 2016
APPL NO 15/331292
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0044 (20130101)
A61B 5/055 (20130101)
A61B 5/113 (20130101)
A61B 5/7207 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5611 (20130101)
G01R 33/56509 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849841 Cotsarelis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) George Cotsarelis (Berwyn, Pennsylvania);  Luis Garza (Baltimore, Maryland)
ABSTRACT This invention provides methods of treating androgenetic alopecia (AGA), acne, rosacea, prostate cancer, and benign prostatic hypertrophy (BPH), comprising the step of contacting a subject with a compound or composition capable of decreasing prostaglandin D2 (PGD2) level or activity, a downstream signaling or receptor pathway thereof, or prostaglandin D2 synthase level or activity; methods of stimulating hair growth, comprising the step of contacting a subject with a compound or composition capable of increasing or decreasing the activity or level of a target gene of the present invention, or with a protein product of the target gene or an analogue or mimetic thereof; and methods of testing for AGA and evaluating therapeutic methods thereof, comprising measuring PGD2 levels.
FILED Monday, February 12, 2018
APPL NO 15/894691
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 2217/05 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0368 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 8/36 (20130101)
A61K 8/365 (20130101)
A61K 8/606 (20130101) Original (OR) Class
A61K 31/557 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 7/00 (20130101)
A61Q 19/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0627 (20130101)
C12N 9/0083 (20130101)
C12N 15/8509 (20130101)
C12N 2830/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849853 Bellinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Andrew Bellinger (Wellesley, Massachusetts);  Shiyi Zhang (Brookline, Massachusetts);  Carlo Giovanni Traverso (Etobicoke, Canada);  Robert S. Langer (Newton, Massachusetts);  Stacy Mo (Darien, Illinois);  Jiaqi Lin (Somerville, Massachusetts);  Angela DiCiccio (Santa Clara, California);  Dean Liang Glettig (Cambridge, Massachusetts);  Lowell L. Wood, Jr. (Bellevue, Washington);  Philip A. Eckhoff (Kirkland, Washington)
ABSTRACT Residence devices as well as their related methods of manufacture and use are generally provided. In some embodiments, a residence device includes a plurality of self-assembling structures that assemble in vivo to form an aggregate structure. Each structure of the plurality of structures includes a first side and a first attachment point that attaches to a second attachment point on another structure of the plurality of structures. The aggregate structure may be sized and shaped to maintain an in vivo position relative to an internal orifice of a subject. The attachment between the first and second attachment points may degrade after a period of time.
FILED Thursday, June 11, 2015
APPL NO 15/317628
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/48 (20130101)
A61K 9/0053 (20130101)
A61K 9/0065 (20130101) Original (OR) Class
A61K 31/65 (20130101)
A61K 31/357 (20130101)
A61K 31/7048 (20130101)
A61K 47/10 (20130101)
A61K 47/32 (20130101)
A61K 47/34 (20130101)
A61K 47/40 (20130101)
A61K 47/42 (20130101)
A61K 47/58 (20170801)
A61K 47/6901 (20170801)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/002 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/4277 (20130101)
C08G 63/08 (20130101)
C08G 83/006 (20130101)
C08G 2230/00 (20130101)

Compositions of Macromolecular Compounds
C08L 33/02 (20130101)
C08L 33/08 (20130101)
C08L 33/14 (20130101)
C08L 2203/02 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849863 States et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) J. Christopher States (Goshen, Kentucky);  Ben Frazier Taylor (New Haven, Connecticut);  John O. Trent (Louisville, Kentucky)
ASSIGNEE(S) UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky)
INVENTOR(S) J. Christopher States (Goshen, Kentucky);  Ben Frazier Taylor (New Haven, Connecticut);  John O. Trent (Louisville, Kentucky)
ABSTRACT Some embodiments of this invention include methods for treating disease and methods for administering a compound of the invention. In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of the invention. Pharmaceutical compositions of some embodiments of the present invention comprise a compound of the invention.
FILED Friday, April 27, 2012
APPL NO 14/114352
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/09 (20130101)
A61K 31/53 (20130101)
A61K 31/132 (20130101)
A61K 31/135 (20130101) Original (OR) Class
A61K 31/136 (20130101)
A61K 31/138 (20130101)
A61K 31/495 (20130101)
A61K 31/4439 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849875 Udugamasooriya et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Houston System (Houston, Texas);  University of Texas Southwestern Medical Center (Dallas, Texas)
ASSIGNEE(S) University of Houston System (Houston, Texas);  Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Damith Gomika Udugamasooriya (Katy, Texas);  Rolf A. Brekken (Dallas, Texas)
ABSTRACT A phosphatidylserine targeted peptoid has been identified with the ability to bind to cancer cells globally and specifically. A dimer of the peptoid decreases cancer cell viability. Use of the dimerized peptoid enhances the efficacy of docetaxel. The peptoid can be used for including but not limited to diagnosing and treating cancer, diagnosing and treating a viral condition, and diagnosing and treating diabetes.
FILED Saturday, July 23, 2016
APPL NO 15/747071
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/343 (20130101) Original (OR) Class
A61K 38/00 (20130101)
A61K 47/55 (20170801)
A61K 49/0056 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/5044 (20130101)
G01N 33/5306 (20130101)
G01N 33/54393 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849895 Bassaganya-Riera et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Landos Biopharma, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) LANDOS BIOPHARMA, INC. (Blacksburg, Virginia)
INVENTOR(S) Josep Bassaganya-Riera (Blacksburg, Virginia);  Adria Carbo Barrios (Blacksburg, Virginia);  Richard Gandour (Blacksburg, Virginia);  Julian D. Cooper (Blacksburg, Virginia);  Raquel Hontecillas (Blacksburg, Virginia)
ABSTRACT Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including infectious disease, autoimmune disease, diabetes, and a chronic inflammatory disease.
FILED Monday, May 04, 2020
APPL NO 16/866169
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/423 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)

Acyclic or Carbocyclic Compounds
C07C 65/40 (20130101)

Heterocyclic Compounds
C07D 213/69 (20130101)
C07D 213/79 (20130101)
C07D 307/60 (20130101)
C07D 307/68 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 403/14 (20130101)
C07D 413/12 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849904 Reh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) University of Washington (Seattle, Washington);  The J. David Gladstone Institutes, a Testamentary Trust Established Under the Will of J. David Gladstone (San Francisco, California)
ASSIGNEE(S) University of Washington (Seattle, Washington);  The J. David Gladstone Institutes, a Teatamentary Trust Established Under the Will of J. David. Gladstone (San Francisco, California)
INVENTOR(S) Thomas A. Reh (Seattle, Washington);  Paul Nakamura (Seattle, Washington);  Sheng Ding (Orinda, California)
ABSTRACT Methods for decreasing rod gene expression in a retina, methods for decreasing the protein products expressed by rod genes in a retina, methods for treating a disease or condition treatable by decreasing rod gene expression or their protein products in a retina, and methods for treating a retinal disease in a subject.
FILED Thursday, June 20, 2019
APPL NO 16/447764
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 9/0051 (20130101)
A61K 31/426 (20130101)
A61K 31/519 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Heterocyclic Compounds
C07D 495/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849910 Cotman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Carl W. Cotman (Santa Ana, California);  Larry E. Overman (Corona del Mar, California);  Shikha Snigdha (Long Beach, California)
ABSTRACT Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.
FILED Friday, March 15, 2019
APPL NO 16/354996
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/202 (20130101)
A61K 31/202 (20130101)
A61K 31/445 (20130101)
A61K 31/445 (20130101)
A61K 31/473 (20130101)
A61K 31/473 (20130101)
A61K 31/522 (20130101)
A61K 31/522 (20130101)
A61K 31/548 (20130101) Original (OR) Class
A61K 31/548 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
A61P 25/22 (20180101)
A61P 25/28 (20180101)

Heterocyclic Compounds
C07D 513/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849912 Sayers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Frederick National Laboratory for Cancer Research (FNLCR)
Federally Funded Research and Development Center (FFRDC)
Operated by Leidos Biomedical Research, Inc. (LBRI) at Frederick, MD
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Thomas Joseph Sayers (Boonsboro, Maryland);  Alan David Brooks (Frederick, Maryland);  Curtis J. Henrich (Rockville, Maryland);  Poonam Tewary (Frederick, Maryland);  James Brislin McMahon (Frederick, Maryland);  Leslie Gunatilaka (Tucson, Arizona);  Ya-Ming Xu (Tucson, Arizona);  Kithsiri Wijeratne (Tucson, Arizona)
ABSTRACT Disclosed is a method of enhancing the response of cancer cells in a mammal to treatment with an apoptosis inducing ligand, which method comprises contacting the cancer cells with an apoptosis inducing ligand in conjunction with an effective amount of a compound of the formula: (I), wherein R1-R14 are as described herein. Also disclosed is a method of inducing apoptosis in cancer cells in a mammal, comprising contacting the cancer cells with the compound described herein and also contacting the cancer cells with an apoptosis inducing ligand, whereby apoptosis is induced in the cancer cells.
FILED Thursday, February 09, 2017
APPL NO 16/076954
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/351 (20130101)
A61K 31/366 (20130101)
A61K 31/585 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Steroids
C07J 17/00 (20130101)
C07J 71/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849914 Ghandehari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, None)
INVENTOR(S) Hamid Ghandehari (Salt Lake City, Utah);  Joseph Cappello (Salt Lake City, Utah);  Azadeh Poursaid (Salt Lake City, Utah);  Mark Martin Jensen (Salt Lake City, Utah)
ABSTRACT Described herein are chemoembolic compositions and agents. The compositions include one or more anti-cancer agents and a silk-elastinlike protein polymer, wherein the compositions are liquids prior to administration to a subject but convert to hydrogels upon administration to the subject. Administration of the chemoembolic compositions to tumor and/or tumor vasculature in a subject having cancer can result in reduced or inhibited blood flow to the tumor as well as localized, sustained release of the anti-cancer agent in the vicinity of the tumor. Reduction in blood flow, in turn, results in a reduction of tumor volume and/or inhibition of tumor growth, while localized release of the anti-cancer agent results in reduced systemic effects and lower overall toxicity of treatment with the compositions.
FILED Tuesday, June 12, 2018
APPL NO 16/006015
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0024 (20130101)
A61K 9/146 (20130101)
A61K 31/44 (20130101)
A61K 31/65 (20130101) Original (OR) Class
A61K 47/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849915 Slusher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Barbara Slusher (Kingsville, Maryland);  Rana Rais (West Friendship, Maryland);  Xuhang Li (Clarksville, Maryland)
ABSTRACT Methods and compounds are disclosed for treating inflammatory bowel disease (IBD) by using Prostate Specific Membrane Antigen (PSMA) inhibitors.
FILED Wednesday, November 14, 2018
APPL NO 16/190792
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/02 (20130101)
A61K 9/0031 (20130101)
A61K 9/0053 (20130101)
A61K 31/194 (20130101)
A61K 31/662 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849922 Rodriguez-Boulan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Enrique Rodriguez-Boulan (New York, New York);  Marcelo Nociari (Summit, New Jersey)
ABSTRACT The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.
FILED Monday, October 07, 2019
APPL NO 16/594740
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/724 (20130101) Original (OR) Class
A61K 47/6951 (20170801)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/92 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/143333 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849960 Puri et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
INVENTOR(S) Raj K. Puri (Potomac, Maryland);  Kathryn C. Zoon (Kensington, Maryland);  Syed R. Husain (Gaithersburg, Maryland);  Daniel S. Green (Silver Spring, Maryland)
ABSTRACT Methods and compositions are disclosed for treating a subject with a cancer. The compositions can include a chimeric molecule comprising an agent that specifically binds the interleukin 4 receptor (IL-4R) and a toxic moiety, an interferon alpha (IFNα), and an interferon gamma (IFNγ). In some non-liming embodiments, the compositions can also include monocytes. The methods disclosed herein include administering a therapeutically effective amount of the compositions taught herein to a subject with cancer, thereby treating the cancer in the subject, wherein cells in the cancer express IL-4R. In some non-liming embodiments, the methods can also include administering monocytes.
FILED Friday, September 07, 2018
APPL NO 16/645431
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/15 (20130101)
A61K 38/212 (20130101) Original (OR) Class
A61K 38/217 (20130101)
A61K 38/1793 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849965 Okada et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hideho Okada (Mill Valley, California);  Yafei Hou (Palo Alto, California)
ABSTRACT Peptides that generate an immune response to glioma-related H3.3 proteins and methods of their use are provided.
FILED Thursday, September 12, 2019
APPL NO 16/569615
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/03 (20130101)
A61K 38/17 (20130101)
A61K 38/19 (20130101)
A61K 38/1764 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 2039/80 (20180801)
A61K 2039/5158 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/4748 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/505 (20130101)
G01N 33/5014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849966 Ruiz-Opazo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Nelson Ruiz-Opazo (Westwood, Massachusetts);  Victoria L. M. Herrera (Westwood, Massachusetts)
ABSTRACT Described herein are methods and compositions relating to methods of inhibiting neutrophils, e.g., inhibiting NET release or NETosis, by means of a DEspR inhibitor, e.g., an anti-DEspR antibody reagent. In some embodiments, the methods can relate to the treatment of a disease, e.g., cancer or a disease wherein neutrophils; NETs; or NETosing or NETting neutrophils contribute to pathogenesis, chronicity, or worsening of disease. In some embodiments, the DEspR inhibitor can be a bi-specific reagent or an antibody-drug conjugate.
FILED Tuesday, September 18, 2018
APPL NO 16/134070
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 39/001109 (20180801) Original (OR) Class
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/12 (20180101)
A61P 11/00 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 16/2863 (20130101)
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 9/50 (20130101)
C12N 9/0065 (20130101)
C12N 9/78 (20130101)

Enzymes
C12Y 111/02002 (20130101)
C12Y 301/21001 (20130101)
C12Y 304/21037 (20130101)
C12Y 304/24007 (20130101)
C12Y 305/03001 (20130101)
C12Y 305/04004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849970 Haynes et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina);  Triad National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Duke University (Durham, North Carolina);  Triad National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Barton F. Haynes (Durham, North Carolina);  Hua-Xin Liao (Durham, North Carolina);  Rebecca M. Lynch (Rockville, Maryland);  Tongqing Zhou (Rockville, Maryland);  Feng Gao (Durham, North Carolina);  Scott Boyd (Palo Alto, California);  George M. Shaw (Philadelphia, Pennsylvania);  Beatrice H. Hahn (Philadelphia, Pennsylvania);  Thomas B. Kepler (Boston, Massachusetts);  Bette T. Korber (Los Alamos, New Mexico);  Peter Kwong (Rockville, Maryland);  John R. Mascola (Rockville, Maryland)
ABSTRACT The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
FILED Monday, January 08, 2018
APPL NO 15/864822
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/57 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/15022 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849975 Blaney et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Joseph E. Blaney (Gettysburg, Pennsylvania);  Jason Paragas (Bethesda, Maryland);  Peter Jahrling (Gaithersburg, Maryland);  Reed Johnson (Frederick, Maryland);  Matthias Schnell (Harleysville, Pennsylvania)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania);  The United States of America, as Represented by the Secretary, Department of Health and Human Services Services (Bethesda, Maryland)
INVENTOR(S) Joseph E. Blaney (Gettysburg, Pennsylvania);  Jason Paragas (Bethesda, Maryland);  Peter Jahrling (Gaithersburg, Maryland);  Reed Johnson (Frederick, Maryland);  Matthias Schnell (Harleysville, Pennsylvania)
ABSTRACT The present invention provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a filovirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a filovirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present invention provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one filovirus glycoprotein or an immunogenic fragment thereof, as well as pharmaceutical compositions comprising the vaccine vectors.
FILED Thursday, February 02, 2012
APPL NO 13/983545
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/08 (20130101)
A61K 39/12 (20130101)
A61K 39/205 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 2039/70 (20130101)
A61K 2039/543 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/5254 (20130101)
A61K 2039/5256 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2760/14134 (20130101)
C12N 2760/14234 (20130101)
C12N 2760/20043 (20130101)
C12N 2760/20134 (20130101)
C12N 2760/20143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849980 Bradner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) James Bradner (Weston, Massachusetts);  Dennis Buckley (Jamaica Plain, Massachusetts);  Georg Winter (Vienna, Austria)
ABSTRACT The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of proliferative disorders. The present application also provides methods for making compounds of the application and intermediates thereof.
FILED Thursday, January 31, 2019
APPL NO 16/264266
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/454 (20130101)
A61K 47/54 (20170801)
A61K 47/542 (20170801) Original (OR) Class
A61K 47/545 (20170801)
A61K 47/549 (20170801)
A61K 47/554 (20170801)

Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
C07D 495/14 (20130101)

Steroids
C07J 3/005 (20130101)
C07J 43/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849986 Goldenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Immunomedics, Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Immunomedics, Inc. (Morris Plains, New Jersey)
INVENTOR(S) David M. Goldenberg (Mendham, New Jersey);  Serengulam V. Govindan (Summit, New Jersey)
ABSTRACT The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan.
FILED Wednesday, April 08, 2020
APPL NO 16/843599
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/337 (20130101)
A61K 31/454 (20130101)
A61K 31/513 (20130101)
A61K 31/675 (20130101)
A61K 31/713 (20130101)
A61K 31/4184 (20130101)
A61K 31/4375 (20130101)
A61K 31/4745 (20130101)
A61K 31/7068 (20130101)
A61K 31/7088 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 41/0038 (20130101)
A61K 45/06 (20130101)
A61K 47/6803 (20170801)
A61K 47/6851 (20170801) Original (OR) Class
A61K 47/6855 (20170801)
A61K 47/6859 (20170801)
A61K 47/6863 (20170801)
A61K 47/6889 (20170801)
A61K 51/1045 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1001 (20130101)
A61N 2005/1021 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/2803 (20130101)
C07K 16/2833 (20130101)
C07K 16/2887 (20130101)
C07K 16/3007 (20130101)
C07K 16/3076 (20130101)
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
C07K 2317/732 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849988 Segura et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Tatiana Segura (Los Angeles, California);  Donald Griffin (Los Angeles, California);  Philip Scumpia (Los Angeles, California)
ABSTRACT An immune-modulating biomaterial comprising a hydrogel scaffold coupled to D-amino acid containing peptides having unexpected properties in vivo is described. For example, certain inflammatory reactions in vivo are significantly increased around the D-peptide containing particles of hydrogel scaffold as compared to particles that contain both L and D peptides or L peptides alone. In addition, these D-peptide compositions are further observed to enhance wound healing and improve the tensile strength of healed tissues. For these and other reasons, the D-amino acid hydrogel materials disclosed herein are useful in a number of methodologies that seek to modulate the immune response and/or wound healing.
FILED Monday, April 10, 2017
APPL NO 16/092202
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/06 (20130101)
A61K 38/4886 (20130101)
A61K 39/02 (20130101)
A61K 39/0011 (20130101)
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 47/60 (20170801)
A61K 47/6903 (20170801) Original (OR) Class
A61K 2039/64 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6093 (20130101)
A61K 2039/55516 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 26/008 (20130101)
A61L 26/008 (20130101)
A61L 26/008 (20130101)
A61L 26/009 (20130101)
A61L 26/0019 (20130101)
A61L 26/0019 (20130101)
A61L 26/0023 (20130101)
A61L 26/0023 (20130101)
A61L 26/0057 (20130101)
A61L 26/0066 (20130101)
A61L 26/0085 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/20 (20130101)
A61L 27/38 (20130101)
A61L 27/50 (20130101)
A61L 27/52 (20130101)
A61L 27/52 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/58 (20130101)
A61L 2300/214 (20130101)
A61L 2300/256 (20130101)
A61L 2400/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 17/02 (20180101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
C08L 71/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849992 Rosenthal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) ALECTOR LLC (South San Francisco, California)
ASSIGNEE(S) ALECTOR LLC (South San Francisco, California)
INVENTOR(S) Arnon Rosenthal (Woodside, California);  Tina Schwabe (South San Francisco, California)
ABSTRACT The present disclosure provides methods of screening for a sortilin binding antagonist. In some embodiments, the methods include incubating an agent with a sortilin protein and a sortilin ligand, where the sortilin protein and sortilin ligand are each attached to a member of a fluorescence donor/acceptor pair, exciting the fluorescence donor of the fluorescence donor/acceptor pair, and detecting fluorescence emitted by the fluorescence donor at a second wavelength and fluorescence emitted by the fluorescence acceptor at a third wavelength. A decrease in the ratio of the fluorescence emitted by the fluorescence acceptor at the third wavelength to the fluorescence emitted by the fluorescence donor at the second wavelength, as compared to the ratio in the absence of the agent, indicates that the agent is a sortilin binding antagonist.
FILED Thursday, April 07, 2016
APPL NO 15/565063
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0056 (20130101) Original (OR) Class

Peptides
C07K 16/2863 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/533 (20130101)
G01N 33/542 (20130101)
G01N 2333/705 (20130101)
G01N 2500/02 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850097 Hadlock et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Theresa A. Hadlock (Concord, Massachusetts);  Nathan T. P. Jowett (Boston, Massachusetts)
ABSTRACT Methods and devices are provided for electrical neural blockade and stimulation of dysfunctional or transferred nerves. For example, a method is provided including identifying a dysfunctional or transferred nerve, attaching an electrode array to the dysfunctional or transferred nerve proximal to the target musculature, delivering an electrical neural blockade signal, and stimulating the dysfunctional or transferred nerve distal to the point of neural blockade. A system is also provided with an electrode array configured to attach proximally to a dysfunctional or transferred nerve and deliver an electrical neural blockade signal with a neuromuscular stimulating electrode array placed distal to the point of neural blockade, and a processor in communication with the electrode arrays and configured to provide stimulation instructions based on the detected activity of the other neuromusculature. A method is further provided for identifying and treating dysfunction arising from aberrant neural regeneration for which contralateral paired neuromusculature exists.
FILED Friday, January 13, 2017
APPL NO 16/069341
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/06 (20130101)
A61N 1/3614 (20170801)
A61N 1/36003 (20130101) Original (OR) Class
A61N 1/36053 (20130101)
A61N 1/36139 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850274 Varghese et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shyni Varghese (La Jolla, California);  Aereas Aung (San Diego, California);  Han Liang Lim (La Jolla, California)
ABSTRACT The disclosure provides for microfluidic devices comprising patterned hydrogels with embedded cells or microtissues.
FILED Saturday, April 09, 2016
APPL NO 15/564617
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101) Original (OR) Class
B01L 2300/123 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0012 (20130101)
C12N 5/0062 (20130101)
C12N 2533/30 (20130101)
C12N 2533/40 (20130101)
C12N 2533/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850278 Wiktor
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Peter Wiktor (Phoenix, Arizona)
ABSTRACT A microreactor array platform and method for sealing a reagent in microreactors of an array of microreactors are provided. The microreactor array platform includes an array of microreactors, and a sealing film having a first surface and an opposite second surface, the sealing film configured to movably seal the array of microreactors. The microreactor array platform also includes an injector for delivering a reagent into the array of microreactors via a fluid path between the array and the second surface of the sealing film, and an applicator for directing a sealing liquid against the first surface of the sealing film. The microreactor array platform further includes a system for creating a pressure differential between the reagent in the injector and a space between the array of microreactors and the second surface of the sealing film.
FILED Wednesday, January 28, 2015
APPL NO 15/114894
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/00286 (20130101)
B01J 2219/00317 (20130101)
B01J 2219/00396 (20130101)
B01J 2219/00414 (20130101)
B01J 2219/00416 (20130101)
B01J 2219/00418 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0282 (20130101)
B01L 3/0293 (20130101)
B01L 3/50851 (20130101)
B01L 3/50853 (20130101) Original (OR) Class
B01L 2200/16 (20130101)
B01L 2200/025 (20130101)
B01L 2200/141 (20130101)
B01L 2200/142 (20130101)
B01L 2200/0642 (20130101)
B01L 2200/0684 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/044 (20130101)
B01L 2300/046 (20130101)
B01L 2300/161 (20130101)
B01L 2300/165 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0822 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0605 (20130101)
B01L 2400/0666 (20130101)
B01L 2400/0683 (20130101)
B01L 2400/0688 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851051 Chattopadhyay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Shrikanta Chattopadhyay (Boston, Massachusetts);  Stuart L. Schreiber (Cambridge, Massachusetts);  Zarko Boskovic (Cambridge, Massachusetts)
ABSTRACT In one aspect, the present invention provides a method of inhibiting proliferation of a multiple myeloma cell, the method comprising contacting the cell with BRD9647, thereby inhibiting proliferation of the cell. In another aspect, the present invention provides a method of treating multiple myeloma in a pre-selected subject, the method comprising administering an effective amount of BRD9647 to the subject, wherein the subject is pre-selected by detecting a mutation in an AZIN1 polynucleotide or polypeptide relative to a reference in a biological sample obtained from the subject. In another aspect, the present invention provides a method of modulating benzoylation of an agent in a cell, the method comprising contacting the cell with BRD9647, thereby modulating benzoylation of an agent in the cell.
FILED Friday, August 12, 2016
APPL NO 15/752507
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/05 (20130101)

Acyclic or Carbocyclic Compounds
C07C 311/51 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851067 Bozik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Knopp Biosciences LLC (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Knopp Biosciences LLC (Pittsburgh, Pennsylvania)
INVENTOR(S) Michael E. Bozik (Wexford, Pennsylvania);  Scott S. Harried (Sun Prairie, Wisconsin);  Lynn Resnick (Pittsburgh, Pennsylvania);  George T. Topalov (Pittsburgh, Pennsylvania);  Justin K. Belardi (Pittsburgh, Pennsylvania);  Charles A. Flentge (Mars, Pennsylvania);  David A. Mareska (McMurray, Pennsylvania);  James S. Hale (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are optionally substituted benzoimidazol-1,2-yl amides, pharmaceutical compositions comprising a therapeutically effective amount of such compounds and a pharmaceutically acceptable excipient, and methods of treating Kv7 associated diseases, such as, epilepsy, amyotrophic lateral sclerosis, various types of pain, hyperexcitability, a dyskinesia, dystonia, mania and tinnitus with such compounds and pharmaceutical compositions.
FILED Tuesday, March 19, 2019
APPL NO 16/358642
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 235/30 (20130101) Original (OR) Class
C07D 405/04 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851072 Larsen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Scott D. Larsen (South Lyon, Michigan);  Richard Neubig (East Lansing, Michigan);  Kim Hutchings (Dexter, Michigan);  Dylan Kahl (Ann Arbor, Michigan);  Erika Mathes Lisabeth (Howell, Michigan)
ABSTRACT Disclosed herein are inhibitors of Rho/MRTF/SRF-mediated gene transcription, and methods for their use in treating or preventing diseases such as cancer and fibrosis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof:
wherein the substituents are as described.
FILED Friday, April 05, 2019
APPL NO 16/376349
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 271/06 (20130101)
C07D 271/113 (20130101) Original (OR) Class
C07D 413/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851095 Panicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ANGION BIOMEDICA CORP. (Uniondale, New York)
ASSIGNEE(S) ANGION BIOMEDICA CORP. (Uniondale, New York)
INVENTOR(S) Bijoy Panicker (Holbrook, New York);  Lambertus J. W. M. Oehlen (Westbury, New York)
ABSTRACT The present invention provides compounds having the general structural formula (I)
and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving elevated levels of aldosterone or abnormal or excessive fibrosis, such as kidney disease and hypertension.
FILED Tuesday, April 30, 2019
APPL NO 16/399888
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/427 (20130101)
A61K 31/4439 (20130101)
A61K 31/7088 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851113 Bannister et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Thomas D. Bannister (Palm Beach Gardens, Florida);  William R. Roush (Jupiter, Florida);  Jun Yong Choi (Jupiter, Florida);  Reji Nair (Palm Beach Gardens, Florida);  Andy S. Tsai (Mystic, Connecticut);  Jitendra K. Mishra (Memphis, Tennessee);  John L. Cleveland (Land O' Lakes, Florida)
ABSTRACT The invention provides heterocyclic compounds of formula A, B, and C as described herein that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.
FILED Thursday, June 13, 2019
APPL NO 16/439950
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/155 (20130101)
A61K 31/155 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/5025 (20130101)
A61K 31/5025 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851133 Arora et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Paramjit S. Arora (Cold Spring Harbor, New York);  Michael G. Wuo (Brooklyn, New York)
ABSTRACT This invention relates to a macrostructure that includes an antiparallel coiled-coil structure shown below or a parallel coiled-coil structure shown below and described in the present application.
FILED Wednesday, June 08, 2016
APPL NO 15/580987
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
C07K 14/00 (20130101)
C07K 2319/73 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851153 Gladwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Mark Thomas Gladwin (Pittsburgh, Pennsylvania);  Jesus Tejero Bravo (Pittsburgh, Pennsylvania)
ABSTRACT Described herein is a new antidote for the rapid elimination of carbon monoxide from hemoglobin, including brain, heart, and red cell hemoglobin. The disclosed therapy involves the use of modified human globins, particularly neuroglobins modified at residue 64 and cytoglobins modified at residue 81, which bind carbon monoxide with extremely high affinity. The monomeric mutant globins are infused into blood, where they rapidly and irreversibly sequester carbon monoxide, and thus limit toxic effects of carbon monoxide on cellular respiration and oxygen transport and utilization.
FILED Friday, August 30, 2019
APPL NO 16/557168
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/00 (20130101)
A61K 38/41 (20130101)

Peptides
C07K 14/795 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851155 Marasco et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts);  Xianchun Tang (West Roxbury, Massachusetts)
ABSTRACT The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
FILED Monday, November 19, 2018
APPL NO 16/195116
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/13 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)
C07K 2319/40 (20130101)
C07K 2319/43 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16043 (20130101)
C12N 2770/20022 (20130101)
C12N 2810/609 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/577 (20130101)
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2469/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851173 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Yong-Jun Liu (Pearland, Texas);  Kui Shin Voo (Pearland, Texas);  Laura Bover (Pearland, Texas);  Naoya Tsurushita (Palo Alto, California);  J. Yun Tso (Menlo Park, California);  Shankar Kumar (Pleasanton, California)
ABSTRACT Human antibodies, preferably recombinant human antibodies, both humanized and chimeric, which specifically bind to human OX40 are disclosed. Preferred antibodies have high affinity for OX40 receptor and activate the receptor in vitro and in vivo. The antibody can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, are useful for modulating receptor activity, e.g., in a human subject suffering from a disorder in which OX40 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies are provided, and methods of synthesizing the recombinant human antibodies, are also provided.
FILED Thursday, December 13, 2018
APPL NO 16/219528
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/2878 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/56 (20130101)
C07K 2317/74 (20130101)
C07K 2317/75 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851174 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Lai-Xi Wang (Ellicott City, Maryland);  Wei Huang (Dundalk, Maryland);  John Giddens (Chesapeake, Virginia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S) Lai-Xi Wang (Ellicott City, Maryland);  Wei Huang (Dundalk, Maryland);  John Giddens (Chesapeake, Virginia)
ABSTRACT A chemoenzymatic method for the preparation of a core-fucoslyated glycoprotein or glycopeptide, including (a) providing an acceptor selected from the group consisting of a fucosylated GlcNAc-protein and fucosylated GlcNAc-peptide; and (b) reacting the acceptor with a donor substrate including an activated oligosaccharide moiety, in the presence of an endoglycosidase (ENGase) selected from Endo;F1, Endo-F2, Endo-F3, Endo-D and related glycosynthase mutants to transfer the oligosaccharide moiety to the acceptor and yield the structure defined core-fucosylated glycoprotein or glycopeptide. The donor substrate includes, in a specific implementation, a synthetic oligosaccharide oxazoline. A related method of fucosylated glycoprotein or fucosylated glycopeptide remodeling with a predetermined natural N-glycan or a tailor-made oligosaccharide moiety, and a method of remodeling an antibody to include a predetermined sugar chain to replace a heterogeneous sugar chain, are also described.
FILED Monday, March 05, 2012
APPL NO 13/411733
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/00 (20130101)
C07K 16/18 (20130101)
C07K 16/2887 (20130101) Original (OR) Class
C07K 2317/41 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851344 Huebsch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) The Regents of The University of California (Oakland, California);  The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California)
ASSIGNEE(S) The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California);  The Regents of The University of California (Oakland, California)
INVENTOR(S) Nathaniel Huebsch (San Bruno, California);  Bruce Conklin (San Francisco, California);  Kevin E. Healy (Moraga, California);  Peter Loskill (Berkeley, California)
ABSTRACT The invention relates to devices, methods, kits, and compositions for in vitro generation of three-dimensional micro-tissues that are accurate models of heart, skeletal muscle, neuronal, and other tissues.
FILED Friday, August 07, 2015
APPL NO 15/329035
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/12 (20130101)
C12M 25/14 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101) Original (OR) Class
C12N 2533/30 (20130101)
C12N 2535/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851354 Goins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) William F. Goins (Pittsburgh, Pennsylvania);  Joseph C. Glorioso, III (Pittsburgh, Pennsylvania);  Justus Bernard Cohen (Pittsburgh, Pennsylvania);  Bonnie L. Reinhart (Pittsburgh, Pennsylvania)
ABSTRACT The invention provides a method for ameliorating chronic pain signaling involving transient receptor potential cation channel subfamily V member 1 (TRPV1) by expressing PP1α in neurons. The invention also provides HSV vectors for expressing PP1α within neurons and compositions comprising such vectors.
FILED Wednesday, November 21, 2018
APPL NO 16/198401
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0019 (20130101)
A61K 9/0085 (20130101)
A61K 38/46 (20130101)
A61K 47/02 (20130101)
A61K 48/005 (20130101)

Peptides
C07K 14/4703 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101) Original (OR) Class
C12N 2710/16643 (20130101)
C12N 2799/028 (20130101)
C12N 2830/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851357 Davidson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
INVENTOR(S) Beverly Davidson (North Liberty, Iowa);  Chie-yu Lin (Boston, Massachusetts);  Edgardo Rodriguez (Gainesville, Florida);  Feng Zhang (Cambridge, Massachusetts)
ABSTRACT The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences especially for use as to nucleotide repeat disorders. Provided are delivery systems and tissues or organ which are targeted as sites for delivery especially for use as to nucleotide repeat disorders. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex or system especially for use as to nucleotide repeat disorders, as well as methods for the design and of such. Also provided are methods of directing CRISPR complex or system formation in eukaryotic cells especially for use as to nucleotide repeat disorders including with consideration of specificity for target recognition and avoidance of toxicity and editing or modifying a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.
FILED Friday, June 10, 2016
APPL NO 15/179711
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 2217/075 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0318 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 38/465 (20130101)
A61K 48/005 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/22 (20130101) Original (OR) Class
C12N 15/63 (20130101)
C12N 15/86 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/907 (20130101)
C12N 15/1082 (20130101)
C12N 2740/15043 (20130101)
C12N 2750/14143 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851360 Calhoun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute on Minority Health and Health Disparities (NIMHD)
Research Centers in Minority Institutions Program (RCMI)
APPLICANT(S) RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) David H. Calhoun (Leonia, New Jersey);  Abass Abdullahi (New York, New York)
ABSTRACT In one embodiment, the invention provides a method of purifying recombinant alpha-galactosidase A. The method includes obtaining a lysate from cells recombinantly expressing alpha-galactosidase A grown in a cell culture medium having non-precipitating phosphate; contacting said lysate with a first chromatography media that binds α-D-mannopyranosyl or α-D-glucopyranosyl; eluting alpha-galactosidase A from the first chromatography media to generate a first eluate having alpha-galactosidase A, wherein said eluting includes at least one elution pause between 4 and 16 hours; contacting the first eluate with a second chromatography media that binds galactose binding proteins; and eluting alpha-galactosidase A from said second chromatography media to generate a second eluate containing said recombinant alpha-galactosidase A.
FILED Monday, March 05, 2018
APPL NO 15/912075
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Separation
B01D 15/3814 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2465 (20130101) Original (OR) Class

Enzymes
C12Y 302/01022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851369 Kalhor et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Office of Science Consolidated Service Center (CSC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Reza Kalhor (East Boston, Massachusetts);  Javier Fernandez Juarez (Cambridge, Massachusetts);  Henry Hung-yi Lee (Brookline, Massachusetts);  George M. Church (Brookline, Massachusetts)
ABSTRACT A method of processing a collection of nucleic acid sequences is provided including connecting an adaptor to one or more or each nucleic acid sequence in the collection to create a processed nucleic acid template library, wherein the adaptor includes a first DNA sequence encoding a PAM sequence and at least a tracr mate.
FILED Wednesday, June 21, 2017
APPL NO 16/310643
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/09 (20130101)
C12N 15/11 (20130101)
C12N 15/102 (20130101)
C12N 15/111 (20130101)
C12N 15/1093 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
C12N 2310/20 (20170501)
C12N 2320/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2525/191 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/02 (20130101)
C40B 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851376 Chand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Hitendra S. Chand (Doral, Florida);  Madhavan Nair (Coral Gables, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Hitendra S. Chand (Doral, Florida);  Madhavan Nair (Coral Gables, Florida)
ABSTRACT The subject invention provides methods, assays, and products for preventing and/or treating pulmonary diseases. The present invention provides methods for identifying inhibitors of lncRNAs, pharmaceutical compositions comprising such inhibitors, and method of using said inhibitors in preventing and/or treating pulmonary airway inflammation. The present invention also develop novel strategies to modulate the mucous response for preventing, intervening, diagnosing and treating pulmonary airway inflammation, asthma, chronic obstructive pulmonary diseases (COPD) and Chronic mucus hypersecretion (CMH) pathogenesis.
FILED Wednesday, October 30, 2019
APPL NO 16/668781
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851400 Bicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Kevin L. Bicker (Rockvale, Tennessee);  Kevin J. Fisher (Collierville, Tennessee);  Ashley E. Corson (Greenbrier, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Kevin L. Bicker (Rockvale, Tennessee);  Kevin J. Fisher (Collierville, Tennessee);  Ashley E. Corson (Greenbrier, Tennessee)
ABSTRACT A solid supported branched linker assay system, including an alpha compound and a beta compounds reversibly tethered to a solid support; a branched linker coupled to the solid support that tethers the alpha and beta compounds to the solid support; the branched linker having two cleavable linkers that are chemically distinct from one another, wherein a first chemically distinct linker tethers the β compound to the branched linker and a second chemically distinct linker tethers the α compound to the branched linker; and at least two means for cleaving the chemically distinct linkers, wherein a first cleavage means is configured to selectively cleave a first chemically distinct linker and a second cleavage means is configured to selectively cleave a second chemically distinct linker.
FILED Monday, March 20, 2017
APPL NO 15/464043
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 5/0806 (20130101)
C07K 5/0812 (20130101)
C07K 17/06 (20130101)
C07K 17/08 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/195 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851421 Lai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Rose Lai (San Ramon, California);  Chao Ling (Beijing, China PRC);  Darryl Nousome (La Palma, California);  Kai Wang (Agoura Hills, California)
ABSTRACT LncRNAs are emerging as important oncogenic drivers in many cancers, but comprehensive, agnostic studies to identify key lncRNAs involved in GBM are lacking. Described herein are new lncRNA involved in gliomagenesis and prognosis, elucidating the biological functions of these relatively unknown biological actors and opening new therapeutic avenues for therapeutic development.
FILED Friday, March 10, 2017
APPL NO 15/456285
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/20 (20170501)
C12N 2310/113 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851423 Ozers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Proteovista LLC (Madison, Wisconsin)
ASSIGNEE(S) Proteovista LLC (Madison, Wisconsin)
INVENTOR(S) Mary Szatkowski Ozers (Madison, Wisconsin);  Christopher L. Warren (Madison, Wisconsin);  Matthew J. Rodesch (Madison, Wisconsin)
ABSTRACT Provided herein is technology relating to genetic determinants of disease and particularly, but not exclusively, to methods, compositions, and systems for identifying single nucleotide polymorphisms that are functionally associated with a disease.
FILED Monday, June 20, 2016
APPL NO 15/739480
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 60/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852220 D'Silva et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland);  THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey);  University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Joseph D'Silva (Hillsboro, Oregon);  Robert H. Austin (Princeton, New Jersey);  Curt Civin (Baltimore, Maryland);  James C. Sturm (Princeton, New Jersey)
ABSTRACT Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
FILED Monday, September 30, 2019
APPL NO 16/588137
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/14 (20130101)
A61K 35/28 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101)
B01L 3/502761 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/1894 (20130101)
B01L 2400/086 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/34 (20130101) Original (OR) Class
G01N 15/1404 (20130101)
G01N 33/5094 (20130101)
G01N 2015/008 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1493 (20130101)
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852278 Agah et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Masoud Agah (Blacksburg, Virginia);  Muhammad Akbar (Blacksburg, Virginia);  Apoorva Garg (Blacksburg, Virginia);  Leyla Nazhandali (Blacksburg, Virginia);  Hamza Shakeel (Blacksburg, Virginia)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Masoud Agah (Blacksburg, Virginia);  Muhammad Akbar (Blacksburg, Virginia);  Apoorva Garg (Blacksburg, Virginia);  Leyla Nazhandali (Blacksburg, Virginia);  Hamza Shakeel (Blacksburg, Virginia)
ABSTRACT The present invention provides a detector and method for detecting substances in complex mixtures. The detector includes a microfabricated preconcentrator, a separation column with an on-chip thermal conductivity detector, a controller for controlling flow and thermal management and a user interface. The thermal conductivity detector includes a first resistor located at an inlet of the separation column and a second resistor located at an outlet of the separation column.
FILED Friday, August 03, 2018
APPL NO 16/054949
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/223 (20130101)
B01J 20/281 (20130101)
B01J 20/3291 (20130101)
B01J 2220/86 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/6052 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852291 Seibel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Eric J. Seibel (Seattle, Washington);  Ronnie Das (Seattle, Washington);  Christopher W. Burfeind (Seattle, Washington);  Thu-mai Nguyen (Villejuif, France)
ABSTRACT An example fluidic device may include a plurality of channels including one or more curved channels having a channel input and a channel output. Each of the one or more curved channels may have a substantially circular cross-section. The fluidic device may also include an input interface between the channel input of the one or more curved channels and an exterior of the fluidic device. The input interface may be configured to receive a biological tissue sample. The fluidic device may also include an output interface between the channel output of the one or more curved channels and the exterior of the fluidic device.
FILED Wednesday, February 03, 2016
APPL NO 15/014610
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/024 (20130101)
B01L 2300/044 (20130101)
B01L 2300/088 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0883 (20130101)
B01L 2300/1827 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/59 (20130101)
G01N 33/4833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852294 Everson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Gregory Thomas Everson (Englewood, Colorado)
ABSTRACT The disclosure provides a method for quantification of hepatic function in a subject comprising measuring the clearance of an orally administered isotopically labeled cholic acid in a subject with, or suspected of having or developing, a hepatic disorder, for example, chronic hepatitis C. The disclosure further provides methods and kits for assessment of hepatic function.
FILED Friday, December 21, 2018
APPL NO 16/230293
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/49 (20130101) Original (OR) Class
G01N 33/92 (20130101)
G01N 33/497 (20130101)
G01N 33/5308 (20130101)
G01N 2800/08 (20130101)
G01N 2800/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852305 Havranek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) James J. Havranek (Clayton, Missouri);  Benjamin Borgo (St. Louis, Missouri)
ABSTRACT Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
FILED Monday, June 22, 2020
APPL NO 16/907813
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101)
C12N 9/93 (20130101)
C12N 9/485 (20130101)
C12N 9/641 (20130101)

Enzymes
C12Y 304/11018 (20130101)
C12Y 601/0101 (20130101)
C12Y 601/0102 (20130101)
C12Y 601/01021 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6824 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852306 Coon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Joshua J. Coon (Middleton, Wisconsin);  Michael S. Westphall (Fitchburg, Wisconsin)
ABSTRACT Described herein are mass spectrometry systems and methods which improve the accuracy of isobaric tag-based quantification by alleviating the pervasive problem of precursor interference and co-isolation of impurities through gas-phase purification. During the gas-phase purification, the mass-to-charge ratios of precursor ions within at least a selected range are selectively changed allowing ions having similar unmodified mass-to-charge ratios to be separated before further isolation, fragmentation or analysis.
FILED Thursday, June 01, 2017
APPL NO 15/611232
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/483 (20130101)
G01N 33/6848 (20130101) Original (OR) Class
G01N 2458/00 (20130101)
G01N 2560/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/04 (20130101)
H01J 49/26 (20130101)
H01J 49/0072 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/24 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852520 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth M. C. Hillman (New York, New York);  Kripa B. Patel (Salem, New Hampshire)
ABSTRACT In a first invention, a SCAPE system routes light from a tilted intermediate image plane (170) to an infinity space disposed behind a third objective (180). A first dichroic beam splitter (52) positioned in the infinity space routes light from the intermediate image plane with different wavelengths in different directions. First and second light detector arrays (90) capture first and second wavelength images, respectively, and optical components (54,56,58,82) route light having the first and second wavelengths towards the first and second light detectors, respectively. In a second invention, a SCAPE system is used to capture a plurality of images while a sample is perturbed (e.g., vibrated, deformed, pushed, pulled, stretched, or squeezed) in order to visualize the impact of the perturbation on the sample.
FILED Tuesday, September 12, 2017
APPL NO 16/333380
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/36 (20130101)
G01J 3/2803 (20130101)
G01J 2003/2826 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/0032 (20130101)
G02B 21/0036 (20130101)
G02B 21/0048 (20130101) Original (OR) Class
G02B 21/0064 (20130101)
G02B 21/0076 (20130101)
G02B 21/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE48335 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Monash University (Clayton, Australia)
ASSIGNEE(S) Monash University (Clayton, Australia)
INVENTOR(S) Jian Li (Carnegie, Australia);  Roger Nation (Ivanhoe East, Australia);  Tony Velkov (Clarinda, Australia);  Philip Thompson (Northcote, Australia);  Kade D. Roberts (Flemington, Australia)
ABSTRACT The present invention relates to antimicrobial compounds and their uses, and in particular to peptide antibiotics which may be used in the treatment of bacterial infections such as Gram-negative bacterial infections, particularly those caused by multidrug-resistant (MDR) pathogens.
FILED Thursday, September 27, 2018
APPL NO 16/144967
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/12 (20130101)

Peptides
C07K 7/62 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10849518 Hartings et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio)
INVENTOR(S) Jed A. Hartings (Cincinnati, Ohio);  J. Adam Wilson (Maineville, Ohio);  Jason M. Hinzman (Taylor Mill, Kentucky);  Norberto Andaluz (Cincinnati, Ohio);  Vincent DiNapoli (Cincinnati, Ohio);  Sebastian Pollandt (Chicago, Illinois)
ABSTRACT Non-invasive electroencephalogram (EEG)-based methods for detecting a spreading depolarization secondary to a brain injury in a patient who exhibits high-amplitude delta activity in at least one channel of a scalp EEG of an injured brain hemisphere of the patient include (a) recording a baseline scalp EEG pattern in the patient at a channel exhibiting high amplitude delta activity; (b) recording a continuous scalp EEG pattern in the patient across a time frame at the at least one channel; and (c) detecting a spreading depolarization during the time frame by observing at least one feature indicative of a spreading depolarization in the continuous scalp EEG recording pattern relative to the baseline scalp EEG pattern at the at least one channel. Scalp EEG recordings are time-compressed prior to analysis. Methods of treating brain-injured patients and triaging brain-injured patients apply the non-invasive EEG methods.
FILED Tuesday, June 30, 2015
APPL NO 15/323130
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0476 (20130101)
A61B 5/04012 (20130101) Original (OR) Class
A61B 5/4094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850081 Boden, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Integra LifeSciences Switzerland Sarl (Le Locle, Switzerland)
ASSIGNEE(S) Integra LifeSciences Switzerland Sáarl (Le Locle, Switzerland)
INVENTOR(S) Thomas Boden, Jr. (Middleboror, Massachusetts);  Patricia D'Aoust (Franklin, Massachusetts);  Alexander Arazawa (Cambridge, Massachusetts)
ABSTRACT Verifying whether a magnetic field resistance mechanism is properly engaged in a drainage valve having an adjustable valve unit including a rotating construct and a pair of primary magnetic elements for programming the valve unit. Using a toolset, a determination is made whether the magnetic field resistance mechanism is properly engaged. An alert is generated whether the magnetic field resistance mechanism is at least one of properly engaged or not properly engaged based on: (i) a measured angular position of a detected one of the pair of primary magnetic elements relative to a direction of flow of fluid through the valve; and/or (ii) a measured distance separation between respective centers of the pair of primary magnetic elements.
FILED Tuesday, September 19, 2017
APPL NO 15/708549
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 27/006 (20130101) Original (OR) Class
A61M 2205/18 (20130101)
A61M 2205/52 (20130101)
A61M 2205/582 (20130101)
A61M 2205/583 (20130101)
A61M 2205/3317 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850099 Skorheim et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Steven W. Skorheim (Canoga Park, California);  Nicholas A. Ketz (Topanga, California);  Jaehoon Choe (Agoura Hills, California);  Praveen K. Pilly (West Hills, California)
ABSTRACT Described is a system for transcranial stimulation to improve cognitive function. During operation, the system generates a customized stimulation pattern based on damaged white matter. Further, data is obtained representing natural brain oscillations of a subject. Finally, while the subject is awake, one or more electrodes are activated in phase with the natural brain oscillations and based on the customized stimulation pattern.
FILED Friday, May 18, 2018
APPL NO 15/983629
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101)
A61M 2021/0072 (20130101)
A61M 2205/52 (20130101)
A61M 2230/10 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/025 (20130101)
A61N 1/0484 (20130101)
A61N 1/36025 (20130101) Original (OR) Class
A61N 1/36034 (20170801)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/30 (20180101)
G16H 20/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850255 Tran
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Dat Tien Tran (Clarksville, Maryland)
ABSTRACT A system and method for synthesizing a nanoparticle material includes dissolving a metal nitrate in deionized water, adding a hydrogel precursor in the deionized water containing the dissolved metal nitrate to create an aqueous solution, heating the aqueous solution, cooling the aqueous solution to create a solid gel, and calcinating the solid gel to create a metal oxide nanoparticle material. The metal oxide nanoparticle material may include a zinc oxide-based nanoparticle material. The hydrogel precursor may include an agarose gel. The solid gel may be calcinated at approximately 600° C. The solid gel may be calcinated for approximately five hours in the presence of air. The aqueous solution may be heated to a boil. The aqueous solution may be heated at a temperature of ≤100° C.
FILED Monday, November 06, 2017
APPL NO 15/803875
ART UNIT 1796 — Optics
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 53/04 (20130101)
B01D 2253/304 (20130101)
B01D 2253/1124 (20130101)
B01D 2257/304 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 6/001 (20130101)
B01J 13/0065 (20130101)
B01J 20/06 (20130101) Original (OR) Class
B01J 20/3057 (20130101)
B01J 20/3078 (20130101)
B01J 20/3085 (20130101)
B01J 20/3433 (20130101)
B01J 20/3483 (20130101)
B01J 20/28007 (20130101)
B01J 20/28016 (20130101)
B01J 20/28019 (20130101)
B01J 20/28059 (20130101)
B01J 20/28071 (20130101)
B01J 2219/00159 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 13/18 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 9/02 (20130101)
C01G 53/40 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/54 (20130101)
C01P 2002/60 (20130101)
C01P 2002/72 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
C01P 2004/64 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/0675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850298 Kuchinski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Corps of Engineers (USACE)
Engineer Research and Development Center (ERDC)
APPLICANT(S) Madeline A. Kuchinski (Lancaster, Pennsylvania)
ASSIGNEE(S) Madeline A. Kuchinski (Lancaster, Pennsylvania)
INVENTOR(S) Madeline A. Kuchinski (Lancaster, Pennsylvania);  Frank A. Kuchinski (Lancaster, Pennsylvania);  Stephen T. Opresko (Lancaster, Pennsylvania);  Cullen L. Hackler (Alpharetta, Georgia)
ABSTRACT An apparatus for coating an object or component includes at least one dispenser for dispensing a falling flow of material and an actuator for projecting the component through the falling flow of material. A landing may also be provided for receiving the coated projectile, the landing adapted for providing a second coating to the coated projectile. Related methods are also disclosed.
FILED Friday, May 05, 2017
APPL NO 15/587882
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 16/20 (20180201)

Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 3/10 (20130101)
B05C 5/005 (20130101)
B05C 5/0216 (20130101) Original (OR) Class

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/24 (20130101)
B05D 1/305 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850495 Matusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Wojciech Matusik (Lexington, Massachusetts);  Desai Chen (Malden, Massachusetts);  Melina Skouras (Cambridge, Massachusetts);  Bo Zhu (Cambridge, Massachusetts)
ABSTRACT System and method for optimizing a three-dimensional model representing a shape of an object to be fabricated from a plurality of materials having known physical properties. The object is designed to exhibit one or more target properties and the three-dimensional model includes a plurality of cells. The system includes at least one processor programmed to receive a data structure including information for a material property gamut of microstructures for the plurality of materials and two or more of the known physical properties of the plurality of materials, and perform a topology optimization process on the three-dimensional model to generate an optimized model, wherein the topology optimization process is constrained based, at least in part, on the information in the received data structure and the one or more target properties.
FILED Friday, January 27, 2017
APPL NO 15/418528
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/386 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 50/00 (20141201) Original (OR) Class

Electric Digital Data Processing
G06F 30/00 (20200101)
G06F 30/23 (20200101)
G06F 2119/18 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850837 Keennon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) AeroVironment, Inc. (Monrovia, California)
ASSIGNEE(S) AEROVIRONMENT, INC. (Simi Valley, California)
INVENTOR(S) Matthew Todd Keennon (Simi Valley, California);  Alexander Andryukov (Simi Valley, California);  Karl Robert Klingebiel (Simi Valley, California);  Henry Thome Won (Sherman Oaks, California)
ABSTRACT A flapping wing driving apparatus includes at least one crank gear capstan rotatably coupled to a crank gear, the at least one crank gear capstan disposed radially offset from a center of rotation of the crank gear; a first wing capstan coupled to a first wing, the first wing capstan having a first variable-radius drive pulley portion; and a first drive linking member configured to drive the first wing capstan, the first drive linking member windably coupled between the first variable-radius drive pulley portion and one of the at least one crank gear capstan; wherein the first wing capstan is configured to non-constantly, angularly rotate responsive to a constant angular rotation of the crank gear.
FILED Friday, July 27, 2018
APPL NO 16/047395
ART UNIT 3634 — Static Structures, Supports and Furniture
CURRENT CPC
Aeroplanes; Helicopters
B64C 33/02 (20130101)
B64C 39/003 (20130101) Original (OR) Class
B64C 39/028 (20130101)
B64C 2201/025 (20130101)
B64C 2201/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851155 Marasco et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts);  Xianchun Tang (West Roxbury, Massachusetts)
ABSTRACT The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
FILED Monday, November 19, 2018
APPL NO 16/195116
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/507 (20130101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/13 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)
C07K 2319/40 (20130101)
C07K 2319/43 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16043 (20130101)
C12N 2770/20022 (20130101)
C12N 2810/609 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/577 (20130101)
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2469/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851251 Fedynyshyn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Theodore H. Fedynyshyn (Sudbury, Massachusetts);  Michael T. Lis (North Andover, Massachusetts);  Jennifer Ann Lewis (Cambridge, Massachusetts)
ABSTRACT An ink formulation for 3D printing comprises a triblock copolymer in a solvent, where the triblock copolymer includes end blocks comprising an aromatic or acrylate polymer and a midblock between the end blocks comprising an aliphatic polymer. The ink formulation exhibits a shear thinning threshold of about 0.02 rad/sec or less. A method of making a 3D printed radiofrequency (RF) device comprises extruding an ink formulation from a deposition nozzle moving relative to a substrate, where the ink formulation comprises a triblock copolymer in a solvent and the triblock copolymer includes end blocks comprising an aromatic or acrylate polymer and a midblock between the end blocks comprising an aliphatic polymer. One or more continuous filaments comprising the ink formulation are deposited in a predetermined pattern on the substrate, and the ink formulation is treated to remove or cure the solvent, thereby forming a printed RF device.
FILED Tuesday, November 01, 2016
APPL NO 15/773282
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/209 (20170801)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/3456 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 236/06 (20130101)
C08F 236/08 (20130101)
C08F 236/10 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/013 (20180101)
C08K 2201/001 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/033 (20130101)
C09D 11/101 (20130101)
C09D 11/106 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851440 Darling et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Gov't as represented by Sec of Army (Adelphia, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washinton, District of Columbia)
INVENTOR(S) Kristopher Allen Darling (Havre De Grace, Maryland);  Scott Martin Grendahl (Newark, Delaware);  Laszlo John Kecskes (Havre De Grace, Maryland);  Kiran N. Solanki (Tempe, Arizona);  Heather Ann Murdoch (Baltimore, Maryland);  Thomas Lee Luckenbaugh (Spring Grove, Pennsylvania);  Anthony James Roberts (Chesapeake City, Maryland);  Billy Chad Hornbuckle (Aberdeen, Maryland)
ABSTRACT Novel metallic systems and methods for their fabrication provide high temperature machine parts formed of a consolidated nano-crystalline metallic material. The material comprises a matrix formed of a solvent metal having a melting point greater than 1,250° C. with crystalline grains having diameters of no more than about 500 nm, and a plurality of dispersed metallic particles formed on the basis of a solute metal in the solvent metal matrix and having diameters of no more than about 200 nm. The particle density along the grain boundary of the matrix is as high as about 2 nm2 of grain boundary area per particle so as to substantially block grain boundary motion and rotation and limit creep at temperatures above 35% of the melting point of the consolidated nano-crystalline metallic material. The machine parts formed may include turbine blades, gears, hypersonics, radiation shielding, and other high temperature parts.
FILED Thursday, September 13, 2018
APPL NO 16/130629
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/00 (20130101)
B22F 3/10 (20130101)
B22F 3/10 (20130101)
B22F 3/20 (20130101)
B22F 3/115 (20130101)
B22F 3/1055 (20130101)
B22F 3/1225 (20130101)
B22F 5/00 (20130101)
B22F 5/008 (20130101)
B22F 5/009 (20130101)
B22F 9/00 (20130101)
B22F 2301/15 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Alloys
C22C 1/045 (20130101)
C22C 1/0433 (20130101)
C22C 19/007 (20130101) Original (OR) Class
C22C 33/0207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851672 Jakomin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Aeronautical Systems Center (ASC)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) John Martin Jakomin (Sharonville, Ohio);  Darrell Glenn Senile (Oxford, Ohio)
ABSTRACT A grommet assembly for mounting to a component of a turbine engine is provided. In one exemplary aspect, the grommet assembly includes a grommet that is removably mounted within a pass-through opening defined by the component. The component may be formed of a composite material. A locking member may be mounted to a body of the grommet. A flange projects from the body. When the grommet is mounted to the component and the locking member is mounted to the body, the body is received by the pass-through opening of the component and the locking member is mounted to the body such that the locking member and the flange clamp the component to secure the grommet to the component. An interface member, such as a pin, may be received by a hole defined by the grommet.
FILED Tuesday, September 04, 2018
APPL NO 16/120952
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 25/243 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/31 (20130101)
F05D 2300/6033 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 5/0258 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851810 Perkins et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Alex Perkins (Arlington, Massachusetts);  Kevin Blankespoor (Arlington, Massachusetts);  Alfred Rizzi (Cambridge, Massachusetts)
ABSTRACT In some applications, a piston of a hydraulic actuator may move at high speeds, and large undesired forces may be generated if the piston reaches an end-stop of the hydraulic actuator at a high speed. The undesired forces may, for example, cause mechanical damage in the hydraulic actuator. A controller may receive information indicative of the piston reaching a first position at a first threshold distance from the end-stop, and, in response, may modify a signal to a valve assembly controlling flow of hydraulic fluid to and from the hydraulic actuator. Further, the controller may receive information indicative of the piston reaching a second position at a second threshold distance closer to the end-stop of the hydraulic actuator, and, in response, the controller may further modify the signal to the valve assembly so as to apply a force on the piston in a away from the end-stop.
FILED Monday, August 26, 2019
APPL NO 16/550903
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 9/09 (20130101)
F15B 11/048 (20130101) Original (OR) Class
F15B 15/22 (20130101)
F15B 15/28 (20130101)
F15B 15/2815 (20130101)
F15B 21/08 (20130101)
F15B 21/087 (20130101)
F15B 2211/665 (20130101)
F15B 2211/755 (20130101)
F15B 2211/6336 (20130101)
F15B 2211/6654 (20130101)
F15B 2211/6656 (20130101)
F15B 2211/6658 (20130101)
F15B 2211/7053 (20130101)
F15B 2211/7653 (20130101)
F15B 2211/8606 (20130101)
F15B 2211/30575 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851838 Lawrence et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Triton Systems, Inc. (Chelmsford, Massachusetts)
ASSIGNEE(S) TRITON SYSTEMS, INC. (Chelmsford, Massachusetts)
INVENTOR(S) Tyson Lawrence (Cambridge, Massachusetts);  Bryan Andrew Smith (Boston, Massachusetts)
ABSTRACT Disclosed are bearing assemblies including a compliant layer within a mounting socket for reducing wear of the bearing.
FILED Wednesday, January 28, 2015
APPL NO 14/607850
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 11/068 (20130101)
F16C 23/045 (20130101)
F16C 27/02 (20130101)
F16C 27/063 (20130101)
F16C 33/74 (20130101) Original (OR) Class
F16C 33/203 (20130101)
F16C 2226/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852078 Reid et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jessica Reid (Chelmsford, Massachusetts);  Mark Bury (Acton, Massachusetts);  Conor Doyle (Sherborn, Massachusetts);  William Kammerer (Leominster, Massachusetts);  William Flaherty (Dunstable, Massachusetts);  Ryan Fontaine (Waltham, Massachusetts)
ABSTRACT A droplet heat exchange system is provided for that includes a heat exchange chamber, at least one injector, and at least one swirler. The chamber is configured to have gas flow through it. The injector can be configured to dispense liquid droplets into the chamber for thermal energy exchange with gas flowing through the chamber. The swirler can disposed within the chamber and can have a body configured to form a spiral gas flow that pushes liquid droplets from the injector, radially outward as gas flows across the body, thereby separating the liquid droplets from the gas flowing across the body and forming a liquid film along an inner wall of the chamber. The collector can be in fluid communication with the heat exchange chamber and configured to collect the liquid film after thermal energy exchange. The collector can be configured to direct at least some of the collected liquid film to the injector for subsequent use.
FILED Thursday, April 04, 2019
APPL NO 16/374964
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction
F28C 1/16 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 3/04 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 25/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852082 Pierce
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Bradley Pierce (Kailua, Hawaii)
ABSTRACT A pistol with a magazine angle swept backward in relation to the barrel increases the barrel length for a given pistol length without deviating from the grip ergonomics of conventional modern pistols. By angling the magazine in this manner, the muzzle velocity of a pistol may be increased for a given pistol length. Alternatively, the pistol length may be minimized for a given muzzle velocity.
FILED Thursday, April 18, 2019
APPL NO 16/387683
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 3/66 (20130101) Original (OR) Class
F41A 9/65 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852111 Recchia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas Recchia (Succasunna, New Jersey);  Yin Chen (West Milford, New Jersey);  Mitchell Stolk (Kearny, New Jersey);  David Hosier (Lafayette, New Jersey);  Sarah Hunt (Mount Arlington, New Jersey)
ABSTRACT Pressure relief holes are sized and positioned on each fin of a projectile to allow high pressure from one side of the fin due to canard and fin interaction to bleed to a low pressure area on the opposite side of the fin. The location of the pressure relief holes target pressure differences due to canard roll control downwash while not affecting pressure differences due to projectile attitude. The fin planform area remains small enough to meet packaging and fire requirements for this type of munition and large enough to aerodynamically stabilize the airframe thereby enabling a more robust pitch and yaw autopilot design.
FILED Monday, March 26, 2018
APPL NO 15/935278
ART UNIT 3619 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/06 (20130101) Original (OR) Class
F42B 10/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852145 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
ASSIGNEE(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  Kamiar Kordari (McLean, Virginia);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glenn Dale, Maryland)
ABSTRACT A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building.
FILED Wednesday, May 23, 2018
APPL NO 15/987774
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/32 (20130101)
G01C 21/165 (20130101)
G01C 21/206 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0252 (20130101)
G01S 19/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852188 Jenkins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Phillip Jenkins (Cleveland Heights, Ohio);  Robert J. Walters (Alexandria, Virginia);  Raymond Hoheisel (Washington, District of Columbia);  David Scheiman (Washington, District of Columbia);  Justin Lorentzen (Washington, District of Columbia)
ABSTRACT A spectral radiometer system, measures incoming light intensity and spectral distribution in different wavelength-bands. An additional data storage device allows recording of the measured data. The inclusive sensor system yields very high sensitivity to incoming light. Furthermore, outstanding linearity of the detector response over several orders of magnitude of incoming light is achieved. Additional benefits are ultra low power consumption and minimum size. The sensor system can be used in remote solar radiation monitoring applications like mobile solar power units as well as in long-term environmental monitoring systems where high precision and low power consumption is a necessity.
FILED Tuesday, April 17, 2018
APPL NO 15/955150
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/32 (20130101) Original (OR) Class
G01J 3/36 (20130101)
G01J 3/0264 (20130101)
G01J 3/0291 (20130101)
G01J 3/2803 (20130101)
G01J 5/30 (20130101)
G01J 5/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852277 Lobkis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Etegent Technologies, Ltd. (Cincinnati, Ohio)
ASSIGNEE(S) ETEGENT TECHNOLOGIES, LTD. (Cincinnati, Ohio)
INVENTOR(S) Oleg Lobkis (Mason, Ohio);  Richard A. Roth (Goshen, Ohio);  Christopher G. Larsen (Cincinnati, Ohio);  Stuart J. Shelley (Cincinnati, Ohio)
ABSTRACT An environmental condition may be measured with a sensor (10) including a wire (20) having an ultrasonic signal transmission characteristic that varies in response to the environmental condition by sensing ultrasonic energy propagated through the wire using multiple types of propagation, and separating an effect of temperature on the wire from an effect of strain on the wire using the sensed ultrasonic energy propagated through the wire using the multiple types of propagation. A positive feedback loop may be used to excite the wire such that strain in the wire is based upon a sensed resonant frequency, while a square wave with a controlled duty cycle may be used to excite the wire at multiple excitation frequencies. A phase matched cone (200, 210) may be used to couple ultrasonic energy between a waveguide wire (202, 212) and a transducer (204, 214).
FILED Thursday, April 09, 2015
APPL NO 15/302836
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/02 (20130101)
F01D 17/085 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 11/00 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/10 (20130101)
G01L 1/106 (20130101)
G01L 11/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/07 (20130101)
G01N 29/12 (20130101)
G01N 29/326 (20130101) Original (OR) Class
G01N 29/2462 (20130101)
G01N 2291/0421 (20130101)
G01N 2291/0426 (20130101)
G01N 2291/0427 (20130101)
G01N 2291/02827 (20130101)
G01N 2291/02872 (20130101)
G01N 2291/02881 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/097 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852366 Ferguson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) David George Ferguson (Takoma Park, Maryland);  Sergey S. Novikov (Baltimore, Maryland);  Anthony Joseph Przybysz (Linthicum, Maryland);  Robert T. Hinkey (Baltimore, Maryland);  Aaron A. Pesetski (Gambrills, Maryland);  Kenneth M. Zick (Baltimore, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) David George Ferguson (Takoma Park, Maryland);  Sergey S. Novikov (Baltimore, Maryland);  Anthony Joseph Przybysz (Linthicum, Maryland);  Robert T. Hinkey (Baltimore, Maryland);  Aaron A. Pesetski (Gambrills, Maryland);  Kenneth M. Zick (Baltimore, Maryland)
ABSTRACT One example includes a magnetic flux source system that includes a tunable current element. The tunable current element includes a SQUID inductively coupled to a first control line that conducts a first control current that induces a bias flux in the SQUID to decrease relative energy barriers between discrete energy states of the tunable current element. The system also includes an inductor in a series loop with the SQUID and inductively coupled to a second control line that conducts a second control current that induces a control flux in the series loop to change a potential energy of the discrete energy states of the tunable current element to set an energy state of the tunable current element to one of the discrete energy states to generate a current that provides a magnetic flux at an amplitude corresponding to the energy state of the at least one tunable current element.
FILED Tuesday, June 26, 2018
APPL NO 16/019210
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/0358 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/223 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852370 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Connie H. Li (Alexandria, Virginia);  Olaf M. J. van 't Erve (Falls Church, Virginia);  Jeremy T. Robinson (Washington, District of Columbia);  Ying Liu (Waterloo, Canada);  Lian Li (Milwaukee, Wisconsin);  Berend T. Jonker (Waldorf, Maryland)
ABSTRACT A device for directly electrically generating and detecting the current-generated spin polarization in topological insulators, comprising a first and fourth contact on a layer of Bi2Se3 and a second contact comprising a ferromagnet/oxide tunnel barrier contact as a detector, and a third contact comprising nonmagnetic metal as a reference contact, a current to the first and fourth contact to produce a net spin polarization, and the spin polarization manifesting as a voltage between the second (magnetic) and third (reference) contacts.
FILED Tuesday, October 23, 2018
APPL NO 16/168583
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/096 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/08 (20130101)
H01L 43/10 (20130101)
H01L 43/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852371 Romalis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey);  Michael Romalis (Princeton, New Jersey);  Haifeng Dong (Beijing, China PRC);  Andrei Baranga (Omer, Israel)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Michael Romalis (Princeton, New Jersey);  Haifeng Dong (Beijing, China PRC);  Andrei Baranga (Omer, Israel)
ABSTRACT Disclosed is a method and apparatus relating generally to scalar atomic magnetometers. The disclosed methods and apparatus utilize a pressurized sample chamber and a high frequency pulsed pump laser to increase spin polarization and significantly suppress heading errors. These methods and apparatus may also include alternating polarization of the pump light between pulses.
FILED Thursday, December 01, 2016
APPL NO 15/780322
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/02 (20130101)
G01R 33/26 (20130101) Original (OR) Class
G01R 33/032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852423 Suarez
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John Suarez (Brooklyn, New York)
ABSTRACT Various embodiments are described that relate to wave transmission from a vehicle, and reception of a response to the transmitted wave. A vehicle wheel can include a sensor that transmits a radio wave in front of the vehicle. The radio wave can reflect off a non-uniformity, such as a speed bump or pothole, and be returned to the sensor. A controller can compare the transmitted wave against the returned wave to identify the existence of the non-uniformity.
FILED Wednesday, March 07, 2018
APPL NO 15/913953
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion
B60B 19/00 (20130101)
B60B 2900/212 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/931 (20130101) Original (OR) Class
G01S 2013/9327 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852433 Chen
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jerry C. Chen (Lexington, Massachusetts)
ABSTRACT Lidar uses light to sense the range to an object. It can be used as a sensor, e.g., for autonomous vehicle navigation, or to generate detailed maps of terrain. A lidar can also sense target speed, optical reflectivity, and spectroscopic signature. As lidars become more widespread, one lidar could interfere with another nearby lidar. Incoherent (time of flight (TOF)) lidars can also be spoofed or hacked. And both coherent and incoherent lidars can be jammed. Modulating the lidar source makes the lidar more resistant to interference, jamming and hacking. In a TOF lidar, each transmitted pulse is modulated in a prearranged or predetermined fashion. A processor in the receiver distinguishes true returns from actual returns based on the modulation or encoding of the transmitted pulses. If the modulation is present, the return signal considered genuine. If the modulation is not present, it is deemed fake.
FILED Thursday, March 15, 2018
APPL NO 15/922397
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/487 (20130101)
G01S 7/4861 (20130101)
G01S 17/26 (20200101) Original (OR) Class
G01S 17/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852475 Boulais et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Kevin A. Boulais (La Plata, Maryland);  Michael H. Fugate (Fredericksburg, Virginia);  Simin Feng (Waldorf, Maryland);  Walter D. Sessions (Marietta, Georgia);  Robert B. Nichols (Yorktown, Virginia);  Victor H. Gehman, Jr. (Dahlgren, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Kevin A. Boulais (La Plata, Maryland);  Michael H. Fugate (Fredericksburg, Virginia);  Simin Feng (Waldorf, Maryland);  Walter D. Sessions (Marietta, Georgia);  Robert B. Nichols (Yorktown, Virginia);  Victor H. Gehman, Jr. (Dahlgren, Virginia)
ABSTRACT A light transmission system is provided for operating an optically responsive circuit. The system includes a light guide film (LGF) to transmit light emitted from its edge, and a scattering node for directing the light to the circuit. The circuit is disposed on a proximate face of the LGF. The scattering node is disposed on a distal face of the LGF opposite the circuit. The circuit can be an integrated circuit, a light detection sensor or a photovoltaic cell.
FILED Thursday, August 18, 2016
APPL NO 15/239828
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/43 (20130101)
G02B 6/4214 (20130101)
G02B 6/12004 (20130101) Original (OR) Class
G02B 2006/12109 (20130101)
G02B 2006/12138 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853060 Kimball et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota)
INVENTOR(S) Colleen Kimball (Ithaca, New York);  Katey Huddleston (Ithaca, New York);  Paul Nicotera (Ithaca, New York)
ABSTRACT A computer-implemented method includes creating, by a computing device, an abstract syntax tree based on a source code file of a software application, the source code file including source code defining operations of the software application. The method also includes traversing, by the computing device, the abstract syntax tree. The method further includes identifying, by the computing device and based on the traversing of the abstract syntax tree, one or more code violations present in the source code. The method also includes generating, by the computing device, at least one refactoring option for the one or more code violations, each refactoring option of the at least one refactoring option representing a change to the source code file that is configured to remediate the associated code violation.
FILED Monday, January 13, 2020
APPL NO 16/740619
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/72 (20130101) Original (OR) Class
G06F 8/427 (20130101)
G06F 8/443 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853073 Fleming, Jr. et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Kermin E. Fleming, Jr. (Hudson, Massachusetts);  Ping Zou (Westborough, Massachusetts);  Mitchell Diamond (Shrewsbury, Massachusetts);  Benjamin Keen (Marlborough, Massachusetts)
ABSTRACT Systems, methods, and apparatuses relating to conditional operations in a configurable spatial accelerator are described. In one embodiment, a hardware accelerator includes an output buffer of a first processing element coupled to an input buffer of a second processing element via a first data path that is to send a first dataflow token from the output buffer of the first processing element to the input buffer of the second processing element when the first dataflow token is received in the output buffer of the first processing element; an output buffer of a third processing element coupled to the input buffer of the second processing element via a second data path that is to send a second dataflow token from the output buffer of the third processing element to the input buffer of the second processing element when the second dataflow token is received in the output buffer of the third processing element; a first backpressure path from the input buffer of the second processing element to the first processing element to indicate to the first processing element when storage is not available in the input buffer of the second processing element; a second backpressure path from the input buffer of the second processing element to the third processing element to indicate to the third processing element when storage is not available in the input buffer of the second processing element; and a scheduler of the second processing element to cause storage of the first dataflow token from the first data path into the input buffer of the second processing element when both the first backpressure path indicates storage is available in the input buffer of the second processing element and a conditional token received in a conditional queue of the second processing element from another processing element is a first value.
FILED Saturday, June 30, 2018
APPL NO 16/024849
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3005 (20130101)
G06F 9/3836 (20130101)
G06F 9/5027 (20130101)
G06F 9/30072 (20130101) Original (OR) Class
G06F 15/825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853177 Casey
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Eoghan Casey (Lausanne, Switzerland)
ABSTRACT Salvaging renderable content includes providing a set of salvaging instructions including a digital pattern associated with digital content to be salvaged, and a predetermined minimum threshold of usefulness of the digital content. A digital data source includes digital content to be salvaged. The digital content is simultaneously read by reviewing the multiple types of digital content independently of one another using separate software salvaging modules to review each specific type of digital content. The digital content is filtered by identifying potentially recoverable digital content. The digital pattern is compared to the filtered digital content to indicate matches between the filtered digital content and the digital pattern. The digital content is reassembled and/or repaired. The matched digital content is validated by determining whether the salvaged digital content is in a form that meets the predetermined minimum threshold of usefulness. The validated digital content is displayed/rendered.
FILED Thursday, June 21, 2018
APPL NO 16/014067
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 7/02 (20130101)
G06F 11/008 (20130101)
G06F 11/1402 (20130101) Original (OR) Class
G06F 11/3013 (20130101)
G06F 16/162 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854090 Ramstrum, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gunnar Gustaf Ramstrum, Jr. (Bonita, California)
ABSTRACT A collision avoidance system and method for a watercraft for computing, visualizing, programming, and executing ship and hazard avoidance. The collision avoidance system and method employs a map visualization, a linear visualization, and a courses of action visualization to automatically provide a clear visualization of threats in real time in a manner which improves operator awareness for timely decision making and avoidance actions. In this regard, the collision avoidance system and method operate to reduce unwanted or unneeded information, ensure the visualization is task oriented as opposed to function oriented, ensure the visualization is intuitive, keep the key measures of the visualization consistent, and automate the searching of hazards across all charts and automate the closest point of approach in both distance and time of nearby tracks.
FILED Thursday, September 27, 2018
APPL NO 16/143626
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 43/18 (20130101)
B63B 49/00 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/203 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/937 (20200101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0206 (20130101)

Traffic Control Systems
G08G 3/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854257 Wang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Delin Zhang (Saint Paul, Minnesota);  Sara A. Majetich (Pittsburgh, Pennsylvania);  Mukund Bapna (Pittsburgh, Pennsylvania)
ABSTRACT A magnetic device may include a layer stack. The layer stack may include a first ferromagnetic layer; a non-magnetic spacer layer on the first ferromagnetic layer, where the non-magnetic spacer layer comprises at least one of Ru, Ir, Ta, Cr, W, Mo, Re, Hf, Zr, or V; a second ferromagnetic layer on the non-magnetic spacer layer; and an oxide layer on the second ferromagnetic layer. The magnetic device also may include a voltage source configured to apply a bias voltage across the layer stack to cause switching of a magnetic orientation of the second ferromagnetic layer without application of an external magnetic field or a current. A thickness and composition of the non-magnetic spacer layer may be selected to enable a switching direction of the magnetic orientation of the second ferromagnetic layer to be controlled by a sign of the bias voltage.
FILED Wednesday, February 05, 2020
APPL NO 16/782845
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)

Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/222 (20130101)
H01L 43/02 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854351 Ganguli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Sabyasachi Ganguli (Beavercreek, Ohio);  Ajit K Roy (Beavercreek, Ohio);  Chenggang Chen (Beavercreek, Ohio)
ABSTRACT An electrically conductive, flexible, strain resilient product is produced by mixing metal coated carbon nanotube networks with a liquid polymeric resin to produce a liquid mixture, and the mixture is cured to produce the product. The networks may include welded junctions between nanotubes formed by depositing and melting metal nanoparticles on the nanotubes to form the metal coating. After the mixing step the liquid mixture may be deposited on a flexible substrate in the form of an electrical circuit. The mixing step may further include mixing the composite with a volatile solvent to produce a selected viscosity. Then, a three-dimensional printer may be used to print the product, such as an electrical circuit, on a substrate. The product is cured in an atmosphere that absorbs the solvent. The conductivity of the mixture may be adjusted by adjusting the weight percentage of the metal coated carbon nanotube networks from 50% to 90%, but a preferred range is between 75% and 85%.
FILED Thursday, August 30, 2018
APPL NO 16/118353
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 2302/403 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Alloys
C22C 2026/002 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854441 Boris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David R. Boris (Silver Spring, Maryland);  Scott G. Walton (Fairfax, Virginia)
ABSTRACT Methods and apparatuses for the production of HF in an electron-beam generated plasma. A gas containing fluorine, hydrogen, and an inert gas such as argon, e.g., Ar/SF6/H2O or Ar/SF6/NH3 flows into a plasma treatment chamber to produce a low pressure gas in the chamber. An electron beam directed into the gas forms a plasma from the gas, with energy from the electron beam dissociating the F-containing molecules, which react with H-containing gas to produce HF in the plasma. Although the concentration of the gas phase HF in the plasma is a very small fraction of the total gas in the chamber, due to its highly reactive nature, the low concentration of HF produced by the method of the present invention is enough to modify the surfaces of materials, performing the same function as aqueous HF solutions to remove oxygen from an exposed material.
FILED Tuesday, June 04, 2019
APPL NO 16/430459
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Cleaning in General; Prevention of Fouling in General
B08B 7/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/321 (20130101)
H01J 37/3233 (20130101)
H01J 37/3244 (20130101)
H01J 2237/335 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02049 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854457 Feigelson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Boris N. Feigelson (Springfield, Virginia);  Francis J. Kub (Arnold, Maryland);  Alan G. Jacobs (Arlington, Virginia)
ABSTRACT An enhanced symmetric multicycle rapid thermal annealing process for removing defects and activating implanted dopant impurities in a III-nitride semiconductor sample. A sample is placed in an enclosure and heated to a temperature T1 under an applied pressure P1 for a time t1. While the heating of the sample is maintained, the sample is subjected to a series of rapid laser irradiations under an applied pressure P2 and a baseline temperature T2. Each of the laser irradiations heats the sample to a temperature Tmax above its thermodynamic stability limit. After a predetermined number of temperature pulses or a predetermined period of time, the laser irradiations are stopped and the sample is brought to a temperature T3 and held at T3 for a time t3 to complete the annealing.
FILED Tuesday, April 30, 2019
APPL NO 16/398355
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/0006 (20130101)
B23K 26/034 (20130101)
B23K 26/082 (20151001)
B23K 26/127 (20130101)
B23K 2101/40 (20180801)
B23K 2103/56 (20180801)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/041 (20130101)
H01L 21/268 (20130101) Original (OR) Class
H01L 21/0455 (20130101)
H01L 21/2258 (20130101)
H01L 21/67115 (20130101)
H01L 29/1602 (20130101)
H01L 29/1608 (20130101)
H01L 29/2003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854740 Pradhan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S) Nihar R. Pradhan (Tallahassee, Florida);  Stephen A. Mcgill (Tallahassee, Florida)
ABSTRACT Systems and methods for providing a phase modulator. The methods comprise creating a Field Effect Transistor (FET) by: placing a crystal structure displaying ambipolarity on a substrate comprising an oxide layer and a conductive silicon layer, the conductive silicon layer providing a gating electrical contact for the phase modulator, and forming source and drain electrical contacts on the crystal structure using e-beam lithography and an e-beam evaporator. The methods also comprising: annealing the FET to improve an interface between the crystal structure and the source and drain electrical contacts; and coating the FET with a dielectric layer to reduce or eliminate hysteresis so that a functionality of the phase modulator is improved.
FILED Monday, June 24, 2019
APPL NO 16/449597
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101)
H01L 21/477 (20130101)
H01L 21/02568 (20130101)
H01L 21/02631 (20130101)
H01L 21/02694 (20130101)
H01L 29/24 (20130101)
H01L 29/7606 (20130101) Original (OR) Class
H01L 29/66969 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854927 Zhamu et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Global Graphene Group, Inc. (Dayton, Ohio)
ASSIGNEE(S) Global Graphene Group, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Springboro, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT The invention provides a method of improving the cycle-life of a rechargeable alkali metal-sulfur cell. The method comprises implementing an anode-protecting layer between an anode active material layer and a porous separator/electrolyte, and/or implementing a cathode-protecting layer between a cathode active material and the porous separator/electrolyte, wherein the anode-protecting layer or cathode-protecting layer comprises a conductive sulfonated elastomer composite having from 0.01% to 50% by weight of a conductive reinforcement material dispersed in a sulfonated elastomeric matrix material and the protecting layer has a thickness from 1 nm to 100 μm, a fully recoverable tensile strain from 2% to 500%, a lithium ion conductivity from 10−7 S/cm to 5×10−2 S/cm, and an electrical conductivity from 10−7 S/cm to 100 S/cm when measured at room temperature. This battery exhibits an excellent combination of high sulfur content, high sulfur utilization efficiency, high energy density, and long cycle life.
FILED Monday, June 18, 2018
APPL NO 16/010975
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/1395 (20130101)
H01M 10/286 (20130101) Original (OR) Class
H01M 10/0459 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854941 Larsen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Etegent Technologies LTD. (Cincinnati, Ohio)
ASSIGNEE(S) ETEGENT TECHNOLOGIES, LTD. (Cincinnati, Ohio)
INVENTOR(S) Christopher G. Larsen (Cincinnati, Ohio);  Oleg Lobkis (Mason, Ohio);  Richard A. Roth (Goshen, Ohio);  Stuart J. Shelley (Cincinnati, Ohio);  Conor Coyan (Stanford, California);  Jason Feldman (Cincinnati, Ohio);  Ann El Demery (Lebanon, Ohio);  Mackenzie Shelley (Ann Arbor, Michigan)
ABSTRACT A broadband waveguide comprising at least one filament configured to transmit a signal therethrough. The broadband waveguide may include one or more reflection suppression techniques including a damping material coupled to at least a portion of the at least one filament and/or at least one reflection point configured thereon. The waveguide may further including a cladding material coupled to the at least one filament. The at least one filament may be coupled to a securing element configured to couple to a surface. The at least one filament may be coupled to a sensor configured to sense the transmitted signal.
FILED Monday, December 31, 2018
APPL NO 16/237397
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/257 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/04 (20130101)
H01P 3/10 (20130101) Original (OR) Class
H01P 11/001 (20130101)

Antennas, i.e Radio Aerials
H01Q 13/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854945 Zhu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Jianxun Zhu (New York, New York);  Peter R. Kinget (Summit, New Jersey)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Jianxun Zhu (New York, New York);  Peter R. Kinget (Summit, New Jersey)
ABSTRACT Circuits for wireless communication on multiple frequency bands are provided. In accordance with some embodiments, transceivers are provided, the transceivers comprising: a first quadrature hybrid having a first in port, a first iso port, a first cpl port, and a first thru port; an antenna coupled to the first in port; a first transmitter having an output coupled to the first cpl port; and a first receiver having an input coupled to the first cpl port.
FILED Monday, May 22, 2017
APPL NO 16/303246
ART UNIT 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 5/18 (20130101) Original (OR) Class
H01P 5/227 (20130101)

Antennas, i.e Radio Aerials
H01Q 21/28 (20130101)

Transmission
H04B 1/00 (20130101)
H04B 1/18 (20130101)
H04B 1/44 (20130101)
H04B 1/52 (20130101)
H04B 1/0458 (20130101)
H04B 1/525 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/001 (20130101)
H04L 5/0023 (20130101)
H04L 5/143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854971 Kaddour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Abdul-Sattar Kaddour (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida);  Constantinos L. Zekios (Miami, Florida)
ASSIGNEE(S) The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S) Abdul-Sattar Kaddour (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida);  Constantinos L. Zekios (Miami, Florida)
ABSTRACT Arrays that are deployable and can change their electromagnetic behavior by changing their shape are provided. An array can include a central panel and at least one foldable panel attached thereto. The central panel can include radiating elements on its upper surface while each foldable panel can have radiating elements on its bottom surface. The array is reconfigurable by each foldable panel being foldable onto the central panel such that its bottom surface then faces upward and covers part or all of the upper surface of the central panel.
FILED Friday, April 24, 2020
APPL NO 16/857449
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/288 (20130101)
H01Q 3/46 (20130101) Original (OR) Class
H01Q 15/148 (20130101)
H01Q 19/104 (20130101)
H01Q 21/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854976 Daniel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) JEM ENGINEERING (Laurel, Maryland)
ASSIGNEE(S) JEM ENGINEERING (Laurel, Maryland)
INVENTOR(S) Chris Daniel (Westminster, Maryland);  David Auckland (College Park, Maryland)
ABSTRACT An antenna includes an electrical excitation component and a core component. The electrical excitation component has and input and a conducting component. The conducting component can conduct current from the input. The core component has a magnetic film, having a substrate and a magnetic material layer, wound around a rectangular mounting plate. The core component can have a magnetic current loop induced therein. The electrical excitation component is arranged such that concentric magnetic fields associated with current conducted through the electrical excitation component are additionally associated with a magnetic current loop within the core component.
FILED Friday, November 10, 2017
APPL NO 15/809217
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/364 (20130101)
H01Q 7/06 (20130101) Original (OR) Class
H01Q 9/265 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855046 Tisdale et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) William A. Tisdale (Belmont, Massachusetts);  Yunan Gao (Cambridge, Massachusetts);  Aaron Jacob Goodman (Cambridge, Massachusetts)
ABSTRACT Phase modulated Optical Parametric Amplification Imaging (p-OPA), can be used to determine the magnitude and the sign of the second-order nonlinear susceptibility of a material, and its spatial variation.
FILED Saturday, October 13, 2018
APPL NO 16/159627
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/0459 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/39 (20130101)
G02F 1/3558 (20130101)
G02F 2001/392 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/302 (20130101)
H01S 3/1083 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855047 Cook
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Gary Cook (Beavercreek, Ohio)
ABSTRACT Systems and methods for employing an electro-optic and photoconductive optical element operating in combination with a polarizer and 100% reflective mirrors to passively control dumping of power from a resonator. The optical element may be constructed of electro-optic material (e.g., Bismuth Silicon Oxide (BSO), Bismuth Germanium Oxide (BGO)), the refractive index of which may be altered by the application of an externally applied electric field. The presence of incident light changes the photoconductivity of the optical element and, therefore, also changes the polarization state of the light passing through the optical element. When combined with a conventional polarizer, the device acts as a self-triggering optical valve to suddenly divert the path of light within a laser to outside of the normal resonator path. Optical power that has been stored inside the laser resonator is then dumped out of the laser in a single, very-high power pulse.
FILED Tuesday, November 06, 2018
APPL NO 16/181515
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/109 (20130101)
H01S 3/115 (20130101)
H01S 3/117 (20130101)
H01S 3/1103 (20130101) Original (OR) Class
H01S 3/1115 (20130101)
H01S 3/08059 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855287 Kay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Matthew James Kay (Bloomington, Indiana);  Matthew John Gadladge (Bloomington, Indiana);  Adam Ray Duncan (Bloomington, Indiana);  Brett J. Hamilton (Heltonville, Indiana);  Andrew Mark Howard (Bloomington, Indiana)
ABSTRACT Various embodiments include providing a MTJ-based LUT and adding a system that short circuits or causes dielectric layer breakdown of selected MTJ junctions to permanently finalize a desired logic state configuration of selected MTJs that is read out by the LUT. Additional embodiments disable dielectric layer breakdown or short circuit control circuits to prevent further alterations to MTJ that have not had their dielectric layers broken down or shorted out. A control system then alters reading out the MTJ-based LUT to sense original higher and lower resistance values of un-shorted/altered MTJs as a higher resistance state and a shorted or dielectric layer that has been broken down as a lower resistance state. This combines the flexibility of a multiple-time programmable LUT-based FPGA with the security and reliability of a one-time programmable LUT-based FPGA which has characteristics of a fixed logic non-programmable integrated circuit or application specific integrated circuit (ASIC).
FILED Wednesday, July 24, 2019
APPL NO 16/520591
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Static Stores
G11C 11/161 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)
G11C 17/16 (20130101)

Pulse Technique
H03K 19/1776 (20130101) Original (OR) Class
H03K 19/17728 (20130101)
H03K 19/17764 (20130101)
H03K 19/17768 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855372 Puckett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Matthew Wade Puckett (Phoenix, Arizona);  Jianfeng Wu (Tucson, Arizona);  Neil A. Krueger (Saint Paul, Minnesota);  Karl D. Nelson (Plymouth, Minnesota)
ABSTRACT Coupled resonators having two resonances are described. A first resonance occurs at the frequency of a pump signal. A second resonance occurs at the frequency of a first Stokes signal. The stop band of the coupled resonators suppresses the second Stokes signal and thus all other higher order Stokes signals. The coupled resonators can be used to more efficiently generate a first Stokes signal having a narrow line width signal.
FILED Wednesday, October 16, 2019
APPL NO 16/654897
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/02076 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/302 (20130101)
H01S 3/0675 (20130101)

Transmission
H04B 10/2537 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855376 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT The present invention reduces the level of optical reflections created in a photonic integrated circuit (PIC) going back into an integrated laser through Reflection Engineering; optimizing the phase/timing and position of optical reflections inherent to a PIC design while adding engineered reflections to the PIC to allow inherent reflections to be reduced or eliminated. The Wavelength Division Multiplexed (WDM) geometric optical isolator of the present invention combines an array of closely spaced WDM lasers with an array of modulators in a novel geometry in order to provide effective optical isolation of the lasers.
FILED Thursday, January 30, 2020
APPL NO 16/777131
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101) Original (OR) Class
H04B 10/50 (20130101)
H04B 10/516 (20130101)
H04B 10/25759 (20130101)
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10849503 Melodia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT A system and method is provided for transmitting signals ultrasonically among a network of implantable and wearable biological devices. The devices includes one or more implantable nodes, which include a sensing and/or actuating unit, at least one gateway node, and at least one access point node. Ultrasonic signals can be transmitted through the body by the implantable nodes to and from the gateway node, for transmission to and from the access point node. The access point node can be connected to the Internet. In this manner, remote instructions can be transmitted to the implantable nodes and data obtained at the implantable nodes can be transmitted to remote sites.
FILED Tuesday, January 26, 2016
APPL NO 15/546423
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101) Original (OR) Class
A61B 5/0024 (20130101)
A61B 5/0026 (20130101)
A61B 5/0028 (20130101)
A61B 5/0205 (20130101)
A61B 5/02438 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/63 (20180101)

Transmission
H04B 11/00 (20130101)

Wireless Communication Networks
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849519 Mendenhall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  UPMC (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) George Stuart Mendenhall (Pittsburgh, Pennsylvania);  Matthew Jones (Pittsburgh, Pennsylvania)
ABSTRACT Disclosed are wearable devices, such as rings and bracelets, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms and methods. The disclosed wearable devices can continuously monitor the wearer's cardiovascular status by measuring heart rate, motion, blood oxygenation, and/or other properties of the wearer. Disclosed wearable devices can further comprise three EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger/wrist, a second electrode on the outer surface adapted to detect a cardiovascular signal from a finger of the opposing hand, and a third electrode on the outer surface of the frame adapted to detect a cardiovascular signal from a EKG lead location on the wearer's chest or leg. The wearable devices can be linked wirelessly to a mobile device that the person can interact with, and can further be linked to other distributed system components and healthcare providers.
FILED Thursday, March 31, 2016
APPL NO 15/560297
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/11 (20130101)
A61B 5/0022 (20130101)
A61B 5/0205 (20130101)
A61B 5/0408 (20130101) Original (OR) Class
A61B 5/0452 (20130101)
A61B 5/0488 (20130101)
A61B 5/683 (20130101)
A61B 5/02438 (20130101)
A61B 5/6826 (20130101)
A61B 5/7275 (20130101)
A61B 5/14552 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/048 (20130101)

Electric Digital Data Processing
G06F 19/00 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/67 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849559 Sereno et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Cogneuro Solutions LLC (Pearland, Texas)
ASSIGNEE(S) CogNeuro Solutions, LLC (Pearland, Texas)
INVENTOR(S) Anne Bibiana Sereno (Pearland, Texas);  Saumil S. Patel (Houston, Texas);  Yujan Shrestha (Houston, Texas);  Stuart Douglass Red (Houston, Texas)
ABSTRACT Portable operatively simple touch screen apparatus uses testing methods and systems that are free of age and language constraints include special signal processing techniques that provide a temporal resolution highly sensitive for probing cognitive function. The embodiments include or make use of one or more modules implemented at least partially in a set of instructions in software and configured to measure user reaction times to visual stimulus on a touch screen device having a capacitive sensor touch-sensitive surface and a detector of audio waves resulting from touch on the touch-sensitive surface. The modules employ recordation of acoustic vibrations resulting from a user's touching a target location on the touch screen surface spaced from a touched starting location on that surface, in one embodiment, to measure temporal response to a visual stimulus placed at the target location.
FILED Tuesday, April 17, 2018
APPL NO 15/954727
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/162 (20130101)
A61B 5/6898 (20130101) Original (OR) Class
A61B 5/7475 (20130101)
A61B 2560/0487 (20130101)
A61B 2562/0204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849593 Hamilton et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) NovaSignal Corp. (Los Angeles, California)
ASSIGNEE(S) NovaSignal Corp. (Los Angeles, California)
INVENTOR(S) Robert Hamilton (Los Angeles, California);  Corey Thibeault (Los Angeles, California);  Michael O'Brien (Los Angeles, California);  Mina Ranjbaran (Los Angeles, California);  Samuel Thorpe (Los Angeles, California);  Nicolas Canac (Los Angeles, California)
ABSTRACT A tool for facilitating medical diagnosis is disclosed herein, including an ultrasound device configured to collect ultrasound data from a patient, a display device, and a processing circuit configured to generate a cerebral blood flow velocity (CBFV) waveform based on the ultrasound data, determine morphology indicators identifying attributes of the CBFV waveform, and configure the display device to display the CBFV waveform and the morphology indicators.
FILED Thursday, June 07, 2018
APPL NO 16/003012
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101) Original (OR) Class
A61B 8/461 (20130101)
A61B 8/463 (20130101)
A61B 8/466 (20130101)
A61B 8/488 (20130101)
A61B 8/0808 (20130101)
A61B 8/0816 (20130101)
A61B 8/0891 (20130101)
A61B 8/4218 (20130101)
A61B 8/4227 (20130101)
A61B 8/4236 (20130101)
A61B 8/4245 (20130101)
A61B 8/4281 (20130101)
A61B 8/4477 (20130101)
A61B 8/5207 (20130101)
A61B 8/5223 (20130101)
A61B 8/5292 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8979 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849667 Almarza et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Alejandro Jose Almarza (Pittsburgh, Pennsylvania);  John A. Holmes (Pittsburgh, Pennsylvania);  William Lee Chung (Mars, Pennsylvania);  Sarah E. Henderson (Irwin, Pennsylvania)
ABSTRACT The invention relates to a biodegradable, magnesium-containing bone screw for implanting into a patient body for use in medical applications, such as, orthopedic, craniofacial and cardiovascular surgery. The bone screw has a head, shaft and tip. The thickness of the head is greater than the thickness of conventional bone screws. The shaft includes both a non-threaded and a threaded portion. The tip is non-threaded and pointed, such as, conical in shape. The composition of the bone screws provide for improved biodegradability and biocompatibility, and the features of the structure of the bone screws facilitate guidance and placement during implantation as well as reduce the potential for mechanical failures.
FILED Thursday, February 20, 2014
APPL NO 14/185007
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/866 (20130101)
A61B 17/8605 (20130101) Original (OR) Class
A61B 17/8635 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849788 Humayun et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Mark S. Humayun (Glendale, California);  Aldo Oregon (Los Angeles, California);  Yi Zhang (Los Angeles, California)
ABSTRACT Several embodiments disclosed herein relate to compositions and methods for treating or repairing damage to ocular tissue. In particular, several embodiments relate to patches that interact, e.g., by way of an adhesive, with damaged retinal tissue to repair or mend a hole, tear or detachment of the retina from underlying ocular tissue. Still additional embodiments relate to self-assembling patches.
FILED Friday, March 18, 2016
APPL NO 15/074909
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/00727 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/24 (20130101)
A61L 27/222 (20130101)
A61L 27/225 (20130101)
A61L 27/227 (20130101)
A61L 2430/16 (20130101)

Compositions of Macromolecular Compounds
C08L 65/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849914 Ghandehari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, None)
INVENTOR(S) Hamid Ghandehari (Salt Lake City, Utah);  Joseph Cappello (Salt Lake City, Utah);  Azadeh Poursaid (Salt Lake City, Utah);  Mark Martin Jensen (Salt Lake City, Utah)
ABSTRACT Described herein are chemoembolic compositions and agents. The compositions include one or more anti-cancer agents and a silk-elastinlike protein polymer, wherein the compositions are liquids prior to administration to a subject but convert to hydrogels upon administration to the subject. Administration of the chemoembolic compositions to tumor and/or tumor vasculature in a subject having cancer can result in reduced or inhibited blood flow to the tumor as well as localized, sustained release of the anti-cancer agent in the vicinity of the tumor. Reduction in blood flow, in turn, results in a reduction of tumor volume and/or inhibition of tumor growth, while localized release of the anti-cancer agent results in reduced systemic effects and lower overall toxicity of treatment with the compositions.
FILED Tuesday, June 12, 2018
APPL NO 16/006015
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0024 (20130101)
A61K 9/146 (20130101)
A61K 31/44 (20130101)
A61K 31/65 (20130101) Original (OR) Class
A61K 47/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850011 Schmidt et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents, the University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas (Austin, Texas)
INVENTOR(S) Christine E. Schmidt (Gainesville, Florida);  Scott A. Zawko (Austin, Texas);  Sarah M. Mayes (Austin, Texas)
ABSTRACT A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
FILED Wednesday, March 20, 2019
APPL NO 16/359102
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/0077 (20130101)
A61F 2002/009 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/16 (20130101)
A61L 31/041 (20130101)
A61L 31/041 (20130101)
A61L 31/041 (20130101)
A61L 31/041 (20130101)
A61L 31/145 (20130101) Original (OR) Class
A61L 31/148 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/075 (20130101)
C08J 5/18 (20130101)
C08J 2305/04 (20130101)
C08J 2405/08 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
C08L 5/08 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850061 Van Reen et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) BROWN UNIVERSITY (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Eliza Van Reen (East Greenwich, Rhode Island);  Gustavo E. Fernandes (Providence, Rhode Island);  Jingming Xu (Providence, Rhode Island);  Mary A. Carskadon (Providence, Rhode Island)
ABSTRACT Systems tune, control, or remediate the intrinsic Circadian clock. A light controller sets spectral distribution, intensity of a bioactive spectral band to shift or entrain circadian response to enhance performance and/or synchronize with local or expected conditions. The systems enhance performance under conditions that might be changing, disrupted, or otherwise present an irregular phase or unnatural change in the subject's circadian status, for example, due to geographically discontinuous activity or spectrally deficient workplace illumination, or due to divergent individual sleep/wake behaviors of subjects in a structured group activity. An illumination recipe that compensates for the deficiency of lighting or of participant sleep or behavior patterns, or age- or disease-related changes, to evoke, shift, or align circadian response and improve behaviors such as classroom alertness, relaxation, excitability, attention, or focus. Systems may receive sensed light values and automatically apply high- and/or low-CER illumination to effect the intended circadian phase.
FILED Tuesday, May 29, 2018
APPL NO 15/991681
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/02 (20130101) Original (OR) Class
A61M 2021/0044 (20130101)
A61M 2205/3306 (20130101)
A61M 2205/3553 (20130101)
A61M 2205/3569 (20130101)
A61M 2205/3592 (20130101)
A61M 2230/06 (20130101)
A61M 2230/50 (20130101)
A61M 2230/63 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0618 (20130101)
A61N 2005/0627 (20130101)
A61N 2005/0628 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850122 Luan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Shuang Luan (Albuquerque, New Mexico);  Daniel Andres Riofrio Almeida (Quito, Ecuador)
ABSTRACT An optimization technique for use with radiation therapy planning that combines stochastic optimization techniques such as Particle Swarm Optimization (PSO) with deterministic techniques to solve for optimal and reliable locations for delivery of radiation doses to a targeted tumor while minimizing the radiation dose experienced by the surrounding critical structures such as normal tissues and organs.
FILED Friday, December 15, 2017
APPL NO 15/843706
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
A61N 5/103 (20130101)
A61N 5/1001 (20130101)
A61N 5/1007 (20130101)
A61N 5/1031 (20130101) Original (OR) Class
A61N 5/1084 (20130101)
A61N 2005/101 (20130101)
A61N 2005/1024 (20130101)
A61N 2005/1034 (20130101)

Electric Digital Data Processing
G06F 19/325 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/006 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850406 Lipton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jeffrey Ian Lipton (Medford, Massachusetts);  Robert MacCurdy (Belchertown, Massachusetts);  Lillian Chin (Cambridge, Massachusetts);  Daniela Rus (Weston, Massachusetts)
ABSTRACT Non-planar shearing auxetic structures, devices, and methods are provided herein. In some embodiments, a non-planar shearing auxetic structure can include a mathematically compact surface with an auxetic pattern of repeating unit cells. The shearing auxetic structure can have a contracted configuration and an expanded configuration, and, when in the compact configuration, can be configured to move to the expanded configuration while generating a net shear on the surface. Shearing auxetic structures can have handedness and, in some embodiments, multiple handed shearing auxetic structures can be joined to create rigid or semi-rigid composite structures, e.g., by arranging differently-handed structures concentrically wherein two or more structures lock against each other. Handed shearing auxetic structures can also provide actuators to convert rotation or other motion to translation, volume expansion, bending, twisting, etc. These structures have many applications, e.g., deployable structures such as pressure vessels, space habitats, fluid carrying vessels, soft robotics, toys, etc.
FILED Friday, April 27, 2018
APPL NO 15/965711
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 15/12 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850495 Matusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Wojciech Matusik (Lexington, Massachusetts);  Desai Chen (Malden, Massachusetts);  Melina Skouras (Cambridge, Massachusetts);  Bo Zhu (Cambridge, Massachusetts)
ABSTRACT System and method for optimizing a three-dimensional model representing a shape of an object to be fabricated from a plurality of materials having known physical properties. The object is designed to exhibit one or more target properties and the three-dimensional model includes a plurality of cells. The system includes at least one processor programmed to receive a data structure including information for a material property gamut of microstructures for the plurality of materials and two or more of the known physical properties of the plurality of materials, and perform a topology optimization process on the three-dimensional model to generate an optimized model, wherein the topology optimization process is constrained based, at least in part, on the information in the received data structure and the one or more target properties.
FILED Friday, January 27, 2017
APPL NO 15/418528
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/386 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 50/00 (20141201) Original (OR) Class

Electric Digital Data Processing
G06F 30/00 (20200101)
G06F 30/23 (20200101)
G06F 2119/18 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851003 Silver et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Matthew Silver (Cambridge, Massachusetts);  Justin Buck (Cambridge, Massachusetts);  Patrick Kiely (Brighton, Massachusetts);  Juan J. Guzman (Medford, Massachusetts);  Zhen Huang (Waltham, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Matthew Silver (Cambridge, Massachusetts);  Justin Buck (Cambridge, Massachusetts);  Patrick Kiely (Brighton, Massachusetts);  Juan J. Guzman (Medford, Massachusetts);  Zhen Huang (Waltham, Massachusetts)
ABSTRACT In one aspect, the present invention provides reactor designs, component designs, and operating schemes for removing nitrates and chemical oxygen demand from any suitable wastewater stream. In another aspect, the invention also provides reactor designs, component designs, and operating schemes designed to modify and improve pH and water quality in wastewater streams.
FILED Thursday, July 21, 2011
APPL NO 13/811149
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 63/04 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 3/005 (20130101)
C02F 3/025 (20130101) Original (OR) Class
C02F 3/302 (20130101)
C02F 2201/007 (20130101)
C02F 2201/46115 (20130101)
C02F 2201/46135 (20130101)
C02F 2209/08 (20130101)
C02F 2209/14 (20130101)
C02F 2209/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851244 Webster et al.
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Office of Integrative Activities (OIA)
APPLICANT(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Dean C. Webster (Fargo, North Dakota);  Eric Krall (Fargo, North Dakota);  Kelly M. Sutko (N. Maple Grove, Minnesota)
ABSTRACT The invention relates to novel acetoacetylated lignin resin compositions comprising the reaction product of lignin and an acetoacetate ester. The invention also relates to novel (meth)acrylated lignin resin compositions comprising the reaction product of lignin and a (meth)acrylic compound. The invention also relates to methods of making the novel acetoacetylated lignin resin compositions and the novel (meth)acrylated lignin resin compositions. The invention also relates to curable coating compositions comprising the novel acetoacetylated lignin resin composition or (meth)acrylated lignin resin composition. The invention also relates to methods of making the curable coating compositions of the invention. The invention also relates to methods of applying curable coating compositions of the invention to substrates. The invention also relates to articles of manufacture comprising a curable coating composition of the invention and a method of making such article.
FILED Thursday, October 26, 2017
APPL NO 15/794500
ART UNIT 1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Derivatives of Natural Macromolecular Compounds
C08H 6/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/10 (20130101)
C08K 5/1515 (20130101)

Compositions of Macromolecular Compounds
C08L 97/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851407 Ly et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Danith H. Ly (Pittsburgh, Pennsylvania);  Wei-Che Hsieh (Pittsburgh, Pennsylvania);  Iulia Sacui (Owensboro, Kentucky);  Arunava Manna (Pittsburgh, Pennsylvania)
ABSTRACT A method of making optically pure preparations of chiral γPNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral γPNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed γPNA, and vice-versa, are provided.
FILED Friday, May 08, 2015
APPL NO 15/308901
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/003 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/686 (20130101)
C12Q 1/6858 (20130101)
C12Q 1/6858 (20130101)
C12Q 2525/107 (20130101)
C12Q 2525/107 (20130101)
C12Q 2525/113 (20130101)
C12Q 2525/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851463 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Joseph Wang (San Diego, California);  Wei Gao (La Jolla, California);  Sirilak Sattayasamitsathit (San Diego, California)
ABSTRACT Methods, structures, devices and systems are disclosed for fabrication of microtube engines using membrane template electrodeposition. Such nanomotors operate based on bubble-induced propulsion in biological fluids and salt-rich environments. In one aspect, fabricating microengines includes depositing a polymer layer on a membrane template, depositing a conductive metal layer on the polymer layer, and dissolving the membrane template to release the multilayer microtubes.
FILED Monday, April 30, 2018
APPL NO 15/967454
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/70 (20130101)
A61K 47/02 (20130101)
A61K 47/34 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/22 (20130101)
B01J 23/42 (20130101)
B01J 23/892 (20130101)
B01J 23/8906 (20130101)
B01J 23/8913 (20130101)
B01J 31/06 (20130101)
B01J 35/02 (20130101)
B01J 35/0006 (20130101)
B01J 35/0033 (20130101)
B01J 37/0215 (20130101)
B01J 37/0244 (20130101)
B01J 2231/005 (20130101)
B01J 2531/005 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/02 (20130101) Original (OR) Class
C25D 1/006 (20130101)
C25D 1/20 (20130101)
C25D 3/12 (20130101)

Producing a Reactive Propulsive Thrust, Not Otherwise Provided for
F03H 99/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/48707 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851627 Hale et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S) Mike Hale (Hopewell Junction, New York);  Keith Hale (Hopewell Junction, New York);  Melinda Sims (Lakeland, Florida)
ABSTRACT A system for extracting landfill gas from a landfill is provided. According to some embodiments, a control system for landfill gas extraction is provided. The control system uses a throttle to control flow of landfill gas extracted from the landfill. The throttle is actuated in use to vary the flow of gas between a well and a gas collection system, in accordance with a control algorithm that adjusts flow as a parameter in controlling gas extraction. The throttle is configured to ensure that there is at least some flow of landfill gas from the landfill to a gas output throughout operation. The extraction system provides an efficient system for landfill gas extraction, while mitigating a risk of creating undesired or unpleasant conditions and/or of violating regulations during operation.
FILED Friday, July 12, 2019
APPL NO 16/510167
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/006 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/12 (20130101) Original (OR) Class

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/36 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/30 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/30 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852145 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
ASSIGNEE(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  Kamiar Kordari (McLean, Virginia);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glenn Dale, Maryland)
ABSTRACT A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building.
FILED Wednesday, May 23, 2018
APPL NO 15/987774
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/32 (20130101)
G01C 21/165 (20130101)
G01C 21/206 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0252 (20130101)
G01S 19/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852214 Qiao et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Wei Qiao (Lincoln, Nebraska);  Jun Wang (Lincoln, Nebraska);  Liyan Qu (Lincoln, Nebraska)
ABSTRACT A wind turbine generator fault detection method is described. The method includes obtaining a first signal from a generator of a wind turbine and a second signal from a vibration sensor coupled to the wind turbine, the first signal representing an output current of the generator, and the second signal being a time-sampled signal representing vibrations of a bearing in the wind turbine. Determining a shaft rotation frequency signal from the first signal, the shaft rotation frequency signal representing a time-varying rotational speed of a shaft of the wind turbine. Resampling an envelope of the second signal based on the shaft rotation frequency signal to provide a third signal, the third signal being an angular sampled signal. Detecting, by the at least one processor, a fault in the bearing of the wind turbine by identifying a characteristic signature of a bearing fault in the third signal.
FILED Monday, May 21, 2018
APPL NO 15/985226
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Wind Motors
F03D 17/00 (20160501)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2240/50 (20130101)
F05B 2260/80 (20130101)
F05B 2270/327 (20130101)
F05B 2270/334 (20130101)
F05B 2270/335 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 13/045 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852272 Herr et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Amy E. Herr (Oakland, California);  Todd A. Duncombe (Oakland, California)
ABSTRACT Provided are devices that include a polymeric separation medium configured to immobilize one or more constituents of interest in the polymeric separation medium and have an increased pore size upon application of an applied stimulus. Systems including the devices, as well as methods of using the devices, are also provided. Embodiments of the present disclosure find use in a variety of different applications, including detecting whether an analyte is present in a fluid sample.
FILED Thursday, June 04, 2015
APPL NO 15/310069
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 15/20 (20130101)
B01D 15/3871 (20130101)
B01D 15/3876 (20130101)
B01D 15/3885 (20130101)
B01D 17/06 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/267 (20130101)
B01J 20/285 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44726 (20130101)
G01N 27/44734 (20130101)
G01N 27/44739 (20130101) Original (OR) Class
G01N 27/44747 (20130101)
G01N 27/44756 (20130101)
G01N 2030/525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852274 Easley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Auburn University (Auburn, Alabama)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Christopher J. Easley (Auburn, Alabama);  Mark D. Holtan (Auburn, Alabama);  Subramaniam Somasundaram (Auburn, Alabama)
ABSTRACT A method of target molecule detection includes simultaneously obtaining a first signal from a first working electrode and a second signal from a second working electrode, wherein the first signal is responsive to interaction of the first recognition element with the target molecule in a sample, and the second signal is indicative of background noise from the sample. The method further includes generating a modified signal that is proportional to an instantaneous difference between the first and second signals, wherein the modified signal indicates an amount of the target molecule present in the sample.
FILED Friday, March 09, 2018
APPL NO 15/917138
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 2563/116 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/48 (20130101) Original (OR) Class
G01N 27/3276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852278 Agah et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Masoud Agah (Blacksburg, Virginia);  Muhammad Akbar (Blacksburg, Virginia);  Apoorva Garg (Blacksburg, Virginia);  Leyla Nazhandali (Blacksburg, Virginia);  Hamza Shakeel (Blacksburg, Virginia)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Masoud Agah (Blacksburg, Virginia);  Muhammad Akbar (Blacksburg, Virginia);  Apoorva Garg (Blacksburg, Virginia);  Leyla Nazhandali (Blacksburg, Virginia);  Hamza Shakeel (Blacksburg, Virginia)
ABSTRACT The present invention provides a detector and method for detecting substances in complex mixtures. The detector includes a microfabricated preconcentrator, a separation column with an on-chip thermal conductivity detector, a controller for controlling flow and thermal management and a user interface. The thermal conductivity detector includes a first resistor located at an inlet of the separation column and a second resistor located at an outlet of the separation column.
FILED Friday, August 03, 2018
APPL NO 16/054949
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/223 (20130101)
B01J 20/281 (20130101)
B01J 20/3291 (20130101)
B01J 2220/86 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/6052 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852291 Seibel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Eric J. Seibel (Seattle, Washington);  Ronnie Das (Seattle, Washington);  Christopher W. Burfeind (Seattle, Washington);  Thu-mai Nguyen (Villejuif, France)
ABSTRACT An example fluidic device may include a plurality of channels including one or more curved channels having a channel input and a channel output. Each of the one or more curved channels may have a substantially circular cross-section. The fluidic device may also include an input interface between the channel input of the one or more curved channels and an exterior of the fluidic device. The input interface may be configured to receive a biological tissue sample. The fluidic device may also include an output interface between the channel output of the one or more curved channels and the exterior of the fluidic device.
FILED Wednesday, February 03, 2016
APPL NO 15/014610
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2200/0647 (20130101)
B01L 2300/024 (20130101)
B01L 2300/044 (20130101)
B01L 2300/088 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/0883 (20130101)
B01L 2300/1827 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/59 (20130101)
G01N 33/4833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852615 Koch et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Tim R. Koch (Corvallis, Oregon);  Jason C. Heikenfeld (Cincinnati, Ohio);  Sayantika Mukherjee (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio);  Crown Electrokinetics Corp. (Corvallis, Oregon)
INVENTOR(S) Tim R. Koch (Corvallis, Oregon);  Jason C. Heikenfeld (Cincinnati, Ohio);  Sayantika Mukherjee (Cincinnati, Ohio)
ABSTRACT A laminate which can serve as either a smart window or a smart mirror is formed using first and second substrates coated with transparent first and second electrodes which are separated by foraminous layer and a third grid-like linear electrode insulated from the first and second electrodes. The foraminous layer includes spacers defining a cell space which is filled with a colloidal ink having first and second particles. The first particles have a positive charge and a first color and second particles having a negative charge and a second color different from the first color. By altering the voltages of the first, second and third electrodes, one can achieve different light transmission characteristics which, for example, can alter the color temperature of the light transmitted through the laminate or enhance reflective colors.
FILED Wednesday, December 02, 2015
APPL NO 15/552924
ART UNIT 2872 — Optics
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/24 (20130101)
E06B 2009/2464 (20130101)

Optical Elements, Systems, or Apparatus
G02B 26/007 (20130101)
G02B 26/026 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/167 (20130101) Original (OR) Class
G02F 1/1676 (20190101)
G02F 2001/1678 (20130101)
G02F 2202/28 (20130101)
G02F 2203/03 (20130101)
G02F 2203/055 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852835 Yetkin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Oguz Yetkin (Dallas, Texas);  Joseph D. Sanford (Dallas, Texas);  Dan O. Popa (Roanoke, Texas);  Lena C. Wallace (Grand Prairie, Texas);  Fahad Mirza (Arlington, Texas);  Roopak Karulkar (Arlington, Texas);  Sumit Kumar Das (Louisville, Kentucky);  Joshua R. Baptist (Louisville, Kentucky);  J. Paul Carpenter (Fort Worth, Texas)
ABSTRACT Systems and methods for manual gesture recognition to control prosthetic devices. Low encumbrance systems utilizing glove-based recognition to control prosthetic devices. Prosthetic control systems and methods are also provided utilizing elements for application on the user's fingernails.
FILED Sunday, April 16, 2017
APPL NO 15/488500
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)
A61F 2002/704 (20130101)
A61F 2002/705 (20130101)
A61F 2002/707 (20130101)

Electric Digital Data Processing
G06F 1/163 (20130101)
G06F 3/014 (20130101)
G06F 3/015 (20130101)
G06F 3/017 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852840 Sinha et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Ayan Sinha (West Lafayette, Indiana);  Chiho Choi (West Lafayette, Indiana);  Joon Hee Choi (West Lafayette, Indiana);  Karthik Ramani (West Lafayette, Indiana)
ABSTRACT A method for hand pose identification in an automated system includes providing depth map data of a hand of a user to a first neural network trained to classify features corresponding to a joint angle of a wrist in the hand to generate a first plurality of activation features and performing a first search in a predetermined plurality of activation features stored in a database in the memory to identify a first plurality of hand pose parameters for the wrist associated with predetermined activation features in the database that are nearest neighbors to the first plurality of activation features. The method further includes generating a hand pose model corresponding to the hand of the user based on the first plurality of hand pose parameters and performing an operation in the automated system in response to input from the user based on the hand pose model.
FILED Monday, December 09, 2019
APPL NO 16/707936
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/017 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/66 (20130101)
G06K 9/00214 (20130101)
G06K 9/00382 (20130101)
G06K 9/00389 (20130101)
G06K 9/4628 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Pictorial Communication, e.g Television
H04N 13/271 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853372 Mueen et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Abdullah Mueen (Albuquerque, New Mexico);  Hossein Hamooni (Santa Clara, California)
ABSTRACT This disclosure describes technologies for pattern matching in data streams. Given one or more patterns of data, and one or more data streams, e.g., streams of measurements made by one or more sensors, this disclosure provides apparatus and techniques for identifying occurrences of the patterns in the data streams. Techniques according to this disclosure generally make use of distribution strategies, as disclosed herein, to distribute the work of pattern identification among multiple processors. Data streams may be divided into multiple segments, and patterns for identification as well as data stream segments may be distributed among the multiple processors.
FILED Friday, December 01, 2017
APPL NO 15/829575
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 16/278 (20190101)
G06F 16/24568 (20190101) Original (OR) Class
G06F 40/103 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853536 Steingrimsson et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Baldur Andrew Steingrimsson (Hillsboro, Oregon);  Anand Kulkarni (Davidson, North Carolina)
ASSIGNEE(S) Imagars LLC (Hillsboro, Oregon)
INVENTOR(S) Baldur Andrew Steingrimsson (Hillsboro, Oregon);  Anand Kulkarni (Davidson, North Carolina)
ABSTRACT This invention presents a transformative design decision support tool (an e-Design Assessment Engine), one that 1. Significantly reduces cost and risk of engineering design projects, over the state of affair, in part through early and automatic detection of design oversights; 2. Offers compelling reduction in the development time of designs, through improved productivity, but without compromising quality or creativity; 3. Offers wide range of flexibility in terms of supporting design processes employed at different design organizations. The design oversights are identified through proper structuring of the engineering design requirements, extraction of relevant design parameters through application program interfaces provided by the pertinent design tools, and mapping against the requirements. Big data analytics are applied to repositories of past designs, for the purpose of improving new designs. The Engine can be used stand-alone, as a part of a design ecosystem, or integrated into existing systems for product lifecycle or data management.
FILED Saturday, June 03, 2017
APPL NO 15/613183
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854003 Korkin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dmitry Korkin (Worcester, Massachusetts);  Pavel Terentiev (Worcester, Massachusetts)
ABSTRACT Embodiments of the innovation relate to a mixed reality device having a mixed reality display and a controller disposed in electrical communication with the mixed reality display. The controller configured to receive topology data associated with a network and three-dimensional (3D) embedded network data associated with the network. The controller is configured to construct a hierarchical data structure from the topology data and the 3D embedded network data. The controller is also configured to display a level of the hierarchical data structure as a virtual object in a 3D space on the mixed reality display, the level of the hierarchical data structure identifying a subset of nodes and a subset of edges of the hierarchical data structure.
FILED Monday, January 15, 2018
APPL NO 15/871632
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/017 (20130101)

Electric Digital Data Processing
G06F 3/013 (20130101)
G06F 3/04815 (20130101)

Image Data Processing or Generation, in General
G06T 17/005 (20130101)
G06T 19/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854313 Pastrana-Rios et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) PROTEIN DYNAMIC SOLUTIONS, INC. (Wakefield, Massachusetts)
ASSIGNEE(S) Protein Dynamic Solutions, Inc. (Wakefield, Massachusetts)
INVENTOR(S) Belinda Pastrana-Rios (Rincon, Puerto Rico);  Jose Javier Rodriguez-Toro (Mayaguez, Puerto Rico)
ABSTRACT Characteristics of proteins, peptides, and/or peptoids can be determined via two-dimensional correlation spectroscopy and/or two-dimensional co-distribution spectroscopies. Spectral data of the proteins, peptides, and/or peptoids can be obtained with respect to an applied perturbation. two-dimensional co-distribution analysis can be applied to generate an asynchronous co-distribution plot for the proteins, peptides, and/or peptoids to define the population of proteins in solution. In the two-dimensional asynchronous plot, a cross peak can be identified as correlating with an auto peak in the two-dimensional correlation synchronous plot associated with aggregation of the proteins, peptides, and/or peptoids. The two-dimensional asynchronous cross peak can be used to determine an order of a distributed presence of spectral intensities with respect to the applied perturbation. For example, for two wavenumbers v1 and v2, the value of the cross peak corresponding to the two wavenumbers can indicate a presence of spectral intensity at v1 relative to the presence of spectral intensity at v2.
FILED Friday, January 20, 2017
APPL NO 16/071032
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)
G01N 21/255 (20130101)
G01N 21/552 (20130101)
G01N 2021/3595 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/00 (20190201) Original (OR) Class
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854740 Pradhan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S) Nihar R. Pradhan (Tallahassee, Florida);  Stephen A. Mcgill (Tallahassee, Florida)
ABSTRACT Systems and methods for providing a phase modulator. The methods comprise creating a Field Effect Transistor (FET) by: placing a crystal structure displaying ambipolarity on a substrate comprising an oxide layer and a conductive silicon layer, the conductive silicon layer providing a gating electrical contact for the phase modulator, and forming source and drain electrical contacts on the crystal structure using e-beam lithography and an e-beam evaporator. The methods also comprising: annealing the FET to improve an interface between the crystal structure and the source and drain electrical contacts; and coating the FET with a dielectric layer to reduce or eliminate hysteresis so that a functionality of the phase modulator is improved.
FILED Monday, June 24, 2019
APPL NO 16/449597
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101)
H01L 21/477 (20130101)
H01L 21/02568 (20130101)
H01L 21/02631 (20130101)
H01L 21/02694 (20130101)
H01L 29/24 (20130101)
H01L 29/7606 (20130101) Original (OR) Class
H01L 29/66969 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854812 Jha et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio)
INVENTOR(S) Rashmi Jha (Wyoming, Ohio);  Andrew Rush (Cincinnati, Ohio);  Eric Herrmann (Beavercreek, Ohio)
ABSTRACT Systems and methods of use and fabrication are described for a non-volatile resistive random access memory (RRAM) multi-terminal device including a first electrode, a second electrode, a metal oxide disposed between the first electrode and the second electrode, and an at least first gate configured to apply a voltage bias to change a resistive state in the metal oxide.
FILED Tuesday, December 24, 2019
APPL NO 16/726371
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/004 (20130101)
G11C 13/0069 (20130101)
G11C 2013/0045 (20130101)
G11C 2013/0078 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/2436 (20130101)
H01L 27/2463 (20130101)
H01L 45/085 (20130101)
H01L 45/146 (20130101) Original (OR) Class
H01L 45/1206 (20130101)
H01L 45/1226 (20130101)
H01L 45/1253 (20130101)
H01L 45/1625 (20130101)
H01L 45/1675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854911 Odom et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Susan A. Odom (Lexington, Kentucky);  Chad Risko (Lexington, Kentucky);  Matthew D. Casselman (Lexington, Kentucky);  Corrine F. Elliott (Lexington, Kentucky);  N. Harsha Attanayake (Lexington, Kentucky);  Subrahmanyam Modekrutti (Lexington, Kentucky)
ABSTRACT Compounds for use in a rechargeable battery are provided, including a compound according to the formula:
wherein R1 and R9 are independently selected from the group consisting of H, alkyl, aryl, perfluoroaryl, perfluoroalkyl, alkylaryl, alkoxyaryl, alkylcarboxyl, aryl carbonyl, haloalkyl, perfluoroalkyl, glycols, haloaryl, a negative electrolyte, and a polymer, so long as when R1 is H, R9 is not H; and R10 is selected from the group consisting of methyl, alkyl, aryl, alkylaryl, alkoxyaryl, alkylcarboxyl, aryl carbonyl, haloalkyl, perfluoroalkyl, perfluoroaryl, glycols, haloaryl, an oligomer, and a polymer.
FILED Wednesday, July 19, 2017
APPL NO 15/654464
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 279/20 (20130101)
C07D 279/22 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/133 (20130101)
H01M 4/587 (20130101)
H01M 8/18 (20130101)
H01M 8/188 (20130101)
H01M 10/056 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0567 (20130101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854937 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Dunwei Wang (Newton, Massachusetts);  Qingmei Cheng (Brighton, Massachusetts)
ABSTRACT Solar rechargeable battery combines the advantages of photoelectrochemical devices and batteries and has emerged as an attractive alternative to artificial photosynthesis for large-scale solar energy harvesting and storage. Due to the low photovoltages by the photoelectrodes, however, most previous demonstrations of unassisted photocharge have been realized on systems with low open circuit potentials (<0.8 V). In response to this critical challenge, here the present disclosure shows that the combined photovoltages exceeding 1.4 V can be obtained using a Ta3N5 nanotube photoanode and a GaN nanowire/Si photocathode with high photocurrents (>5 mA/cm2). The photoelectrode system makes it possible to operate a 1.2 V alkaline anthraquinone/ferrocyanide redox battery with a high ideal solar-to-chemical conversion efficiency of 3.0% without externally applied potentials. Importantly, the photocharged battery was successfully discharged with a high voltage output.
FILED Wednesday, January 16, 2019
APPL NO 16/248940
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/18 (20130101)
H01M 8/188 (20130101)
H01M 14/005 (20130101) Original (OR) Class
H01M 2300/0014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855564 Korkin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dmitry Korkin (Worcester, Massachusetts);  Pavel Terentiev (Worcester, Massachusetts)
ABSTRACT A mixed reality device includes a mixed reality display and a controller disposed in electrical communication with the mixed reality display. The controller is configured to display a hierarchical data structure as a virtual object in a 3D space on the mixed reality display, the hierarchical data structure constructed from topology data associated with a network and three-dimensional (3D) embedded network data associated with the network; receive a hierarchy traversal command relative to at least one node of a first level of the hierarchical data structure; and, in response to receiving the hierarchy traversal command, display at least one node of the second level of the hierarchical data structure on the mixed reality display.
FILED Tuesday, January 15, 2019
APPL NO 16/248391
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image Data Processing or Generation, in General
G06T 19/003 (20130101)
G06T 19/006 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/08 (20130101)
H04L 43/10 (20130101)
H04L 43/045 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10849970 Haynes et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina);  Triad National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Duke University (Durham, North Carolina);  Triad National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Barton F. Haynes (Durham, North Carolina);  Hua-Xin Liao (Durham, North Carolina);  Rebecca M. Lynch (Rockville, Maryland);  Tongqing Zhou (Rockville, Maryland);  Feng Gao (Durham, North Carolina);  Scott Boyd (Palo Alto, California);  George M. Shaw (Philadelphia, Pennsylvania);  Beatrice H. Hahn (Philadelphia, Pennsylvania);  Thomas B. Kepler (Boston, Massachusetts);  Bette T. Korber (Los Alamos, New Mexico);  Peter Kwong (Rockville, Maryland);  John R. Mascola (Rockville, Maryland)
ABSTRACT The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
FILED Monday, January 08, 2018
APPL NO 15/864822
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/57 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/15022 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850266 White et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Mississippi State University (Starkville, Mississippi)
ASSIGNEE(S) Mississippi State University (Starkville, Mississippi)
INVENTOR(S) Mark G. White (Spring Hill, Florida);  Shetian Liu (Bartlesville, Oklahoma)
ABSTRACT The present invention provides a novel process and system in which a mixture of carbon monoxide and hydrogen synthesis gas, or syngas, is converted into hydrocarbon mixtures composed of high quality gasoline components, aromatic compounds, and lower molecular weight gaseous olefins in one reactor or step. The invention utilizes a novel molybdenum-zeolite catalyst in high pressure hydrogen for conversion, as well as a novel rhenium-zeolite catalyst in place of the molybdenum-zeolite catalyst, and provides for use of the novel catalysts in the process and system of the invention.
FILED Monday, September 25, 2017
APPL NO 15/714238
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/28 (20130101)
B01J 29/26 (20130101)
B01J 29/48 (20130101)
B01J 29/076 (20130101)
B01J 29/78 (20130101)
B01J 29/084 (20130101)
B01J 29/166 (20130101)
B01J 29/0341 (20130101)
B01J 29/7815 (20130101) Original (OR) Class
B01J 29/7876 (20130101)
B01J 37/0201 (20130101)
B01J 2229/18 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 2/334 (20130101)
C10G 2400/30 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/08 (20130101)
C10L 3/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10850324 Seals et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee);  UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Roland D. Seals (Oak Ridge, Tennessee);  Paul A. Menchhofer (Clinton, Tennessee);  James O. Kiggans, Jr. (Oak Ridge, Tennessee)
ABSTRACT Disclosed herein are structures comprising a titanium, zirconium, or hafnium powder particle with titanium carbide, zirconium carbide, or hafnium carbide (respectively) nano-whiskers grown directly from and anchored to the powder particle. Also disclosed are methods for fabrication of such structures, involving heating the powder particles and exposing the particles to an organic gas.
FILED Monday, February 10, 2020
APPL NO 16/786286
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/02 (20130101)
B22F 1/0007 (20130101) Original (OR) Class
B22F 1/0018 (20130101)
B22F 2301/205 (20130101)
B22F 2302/10 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/914 (20170801)
C01B 32/921 (20170801)

Alloys
C22C 32/0052 (20130101)
C22C 47/00 (20130101)
C22C 49/04 (20130101)
C22C 49/14 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/32 (20130101)
C23C 16/0218 (20130101)
C23C 16/4417 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/005 (20130101)
C30B 29/36 (20130101)
C30B 29/62 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851106 Li
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Jian Li (Tempe, Arizona)
ABSTRACT Thermally assisted delayed fluorescent materials with triad-type materials for use in full color displays and lighting applications with the following generic structures are provided:
FILED Tuesday, August 27, 2019
APPL NO 16/552585
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101)
C07D 471/14 (20130101) Original (OR) Class
C07D 471/22 (20130101)
C07D 493/22 (20130101)
C07D 495/14 (20130101)
C07D 495/22 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1018 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0061 (20130101)
H01L 51/0071 (20130101)
H01L 51/0072 (20130101)
H01L 51/5012 (20130101)
H01L 51/5016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851369 Kalhor et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Office of Science Consolidated Service Center (CSC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Reza Kalhor (East Boston, Massachusetts);  Javier Fernandez Juarez (Cambridge, Massachusetts);  Henry Hung-yi Lee (Brookline, Massachusetts);  George M. Church (Brookline, Massachusetts)
ABSTRACT A method of processing a collection of nucleic acid sequences is provided including connecting an adaptor to one or more or each nucleic acid sequence in the collection to create a processed nucleic acid template library, wherein the adaptor includes a first DNA sequence encoding a PAM sequence and at least a tracr mate.
FILED Wednesday, June 21, 2017
APPL NO 16/310643
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/09 (20130101)
C12N 15/11 (20130101)
C12N 15/102 (20130101)
C12N 15/111 (20130101)
C12N 15/1093 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
C12N 2310/20 (20170501)
C12N 2320/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2525/191 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/02 (20130101)
C40B 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851446 Anderson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Iver E. Anderson (Ames, Iowa);  Emma Marie Hamilton White (Ames, Iowa);  Matthew J. Kramer (Ankeny, Iowa);  Aaron G. Kassen (Ames, Iowa);  Kevin W. Dennis (Ames, Iowa)
ABSTRACT Magnet microstructure manipulation in the solid state by controlled application of a sufficient stress in a direction during high temperature annealing in a single-phase region of heat-treatable magnet alloys, e.g., alnico-type magnets is followed by magnetic annealing and draw annealing to improve coercivity and saturation magnetization properties. The solid-state process can be termed highly controlled abnormal grain growth (hereafter AGG) and will make aligned sintered anisotropic magnets that meet or exceed the magnetic properties of cast versions of the same alloy types.
FILED Tuesday, March 28, 2017
APPL NO 15/530951
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 21/04 (20130101)
C22C 21/10 (20130101)
C22C 21/14 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/004 (20130101) Original (OR) Class
C22F 1/057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851658 Hafner
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S) Matthew Troy Hafner (Honea Path, South Carolina)
ABSTRACT A nozzle assembly is disclosed, including a CMC nozzle shell, a nozzle spar, and an endwall. The CMC nozzle shell includes a CMC composition and an interior cavity. The nozzle spar is partially disposed within the interior cavity and includes a metallic composition, a cross-sectional conformation, a plurality of spacers protruding from the cross-sectional conformation, the plurality of spacers contacting the CMC nozzle shell, and a spar cap. The endwall includes at least one surface in lateral contact with the spar cap and maintains a lateral orientation of the CMC nozzle shell and the nozzle spar relative to the endwall. The lateral orientation maintains a predetermined throat area of the nozzle assembly. A method for forming the nozzle assembly includes inserting the nozzle spar into the interior cavity, rotating the CMC nozzle shell and the nozzle spar laterally relative to the endwall, and maintaining the lateral orientation.
FILED Monday, February 06, 2017
APPL NO 15/425545
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/282 (20130101)
F01D 5/284 (20130101)
F01D 9/041 (20130101) Original (OR) Class
F01D 9/042 (20130101)
F01D 9/044 (20130101)
F01D 25/005 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/232 (20130101)
F05D 2240/128 (20130101)
F05D 2250/60 (20130101)
F05D 2250/121 (20130101)
F05D 2250/141 (20130101)
F05D 2300/17 (20130101)
F05D 2300/174 (20130101)
F05D 2300/175 (20130101)
F05D 2300/604 (20130101)
F05D 2300/6033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852214 Qiao et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Wei Qiao (Lincoln, Nebraska);  Jun Wang (Lincoln, Nebraska);  Liyan Qu (Lincoln, Nebraska)
ABSTRACT A wind turbine generator fault detection method is described. The method includes obtaining a first signal from a generator of a wind turbine and a second signal from a vibration sensor coupled to the wind turbine, the first signal representing an output current of the generator, and the second signal being a time-sampled signal representing vibrations of a bearing in the wind turbine. Determining a shaft rotation frequency signal from the first signal, the shaft rotation frequency signal representing a time-varying rotational speed of a shaft of the wind turbine. Resampling an envelope of the second signal based on the shaft rotation frequency signal to provide a third signal, the third signal being an angular sampled signal. Detecting, by the at least one processor, a fault in the bearing of the wind turbine by identifying a characteristic signature of a bearing fault in the third signal.
FILED Monday, May 21, 2018
APPL NO 15/985226
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Wind Motors
F03D 17/00 (20160501)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2240/50 (20130101)
F05B 2260/80 (20130101)
F05B 2270/327 (20130101)
F05B 2270/334 (20130101)
F05B 2270/335 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 13/045 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852384 Allnutt et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Daniel Allnutt (Kansas City, Missouri);  Daniel Longo (Kansas City, Missouri)
ABSTRACT A device and method for detecting presence of a wireless communication device having an antenna with intrinsic characteristics includes a transmitter, a receiver, a memory element, and a processing element. The transmitter may send a first signal to the antenna of the wireless communication device. The receiver may receive a second signal from the antenna of the wireless communication device, the second signal being a first portion of the first signal that is reflected by the antenna based on intrinsic characteristics of the antenna. The memory element may store intrinsic characteristic information for the antenna. The processing element may determine presence of the wireless communication device by analyzing the second signal against the intrinsic characteristic information stored in the memory element.
FILED Wednesday, January 31, 2018
APPL NO 15/885128
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/20 (20130101) Original (OR) Class

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/12 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/2601 (20130101)

Wireless Communication Networks
H04W 8/005 (20130101)
H04W 88/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852706 Lian et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jianming Lian (Richland, Washington);  Karanjit Kalsi (Richland, Washington);  Draguna Vrabie (West Richland, Washington);  Soumya Kundu (Richland, Washington)
ABSTRACT Methods and apparatus are disclosed for extracting maximal frequency response potential in controllable loads. In one example, a method includes assigning a fitness metric to at least one electrical device coupled to a power grid, assigning a frequency threshold based on the fitness metric, and transmitting the assigned frequency threshold to the at least one electrical device. The fitness metric can be based at least in part on an availability component and a quality component associated with the at least one device and the frequency threshold can cause the at least one electrical device to activate autonomously based on a frequency of the power grid.
FILED Tuesday, July 10, 2018
APPL NO 16/031949
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/045 (20130101) Original (OR) Class
G05B 19/0426 (20130101)
G05B 2219/21109 (20130101)
G05B 2219/25268 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/14 (20130101)
H02J 3/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10853075 Agrawal et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S) Varun Agrawal (Acton, Massachusetts);  John Kalamatianos (Arlington, Massachusetts);  Adithya Yalavarti (Acton, Massachusetts);  Jingjie Qian (Arlington, Massachusetts)
ABSTRACT An electronic device handles accesses of a branch prediction functional block when executing instructions in program code. The electronic device includes a processor having the branch prediction functional block that provides branch prediction information for control transfer instructions (CTIs) in the program code and a minimum predictor use (MPU) functional block. The MPU functional block determines, based on a record associated with a given fetch group of instructions, that a specified number of subsequent fetch groups of instructions that were previously determined to include no CTIs or conditional CTIs that were not taken are to be fetched for execution in sequence following the given fetch group. The MPU functional block then, when each of the specified number of the subsequent fetch groups is fetched and prepared for execution, prevents corresponding accesses of the branch prediction functional block for acquiring branch prediction information for instructions in that subsequent fetch group.
FILED Monday, December 23, 2019
APPL NO 16/725203
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3804 (20130101) Original (OR) Class
G06F 9/3808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854417 Lewellen et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) John Lewellen (Los Alamos, New Mexico);  John Harris (Albuquerque, New Mexico)
ABSTRACT Radial radio frequency (RF) electron guns and radial RF electron gun systems are provided that are capable of generating an electron beam that can propagate either radially inward, towards the axis of a cylinder, or radially outward from the axis. A beam source capable of generating a radially inwardly propagating electron beam, while perhaps not particularly useful as a source for a higher-energy accelerator, offers potential advantages for materials processing, as the geometry allows irradiation from all sides of an enclosed material flow with a single structure. Other potential applications include, but are not limited to, atmospheric plasma generation, radiation damage testing, and possibly, novel electron lens-type devices for hadron accelerators.
FILED Friday, October 26, 2018
APPL NO 16/171458
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 29/04 (20130101)
H01J 29/481 (20130101)
H01J 29/485 (20130101)
H01J 31/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854771 Conway et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Adam Conway (Livermore, California);  Mihail Bora (Livermore, California);  Paulius Vytautas Grivickas (Livermore, California);  Lars Voss (Livermore, California)
ABSTRACT Techniques, systems, and devices are disclosed that relate to coaxial photoconductive switch modules. The coaxial photoconductive switch may include an outer conductor, an inner conductor, and a photoconductive material positioned between the inner conductor and the outer conductor. The inner conductor, the outer conductor, and the photoconductive material have a predetermined height. A bias voltage may be applied between the inner conductor and the outer conductor. When light of a predetermined wavelength and a predetermined intensity is incident on the photoconductive material, the photoconductive material may break down allowing a current to flow through the photoconductive material between the inner conductor and the outer conductor.
FILED Wednesday, May 01, 2019
APPL NO 16/401016
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 2006/12145 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/161 (20130101) Original (OR) Class
H01L 31/0224 (20130101)

Pulse Technique
H03K 17/78 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 2201/10121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854810 Ketterson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Qorvo US, Inc. (Greensboro, North Carolina)
ASSIGNEE(S) Qorvo US, Inc. (Greensboro, North Carolina)
INVENTOR(S) Andrew Arthur Ketterson (Dallas, Texas);  Xing Gu (Allen, Texas);  Yongjie Cui (Plano, Texas);  Xing Chen (Plainfield, Illinois)
ABSTRACT A passive magnetic device (PMD) has a base electrode, a multi-port signal structure (MPSS), and a substrate therebetween. The MPSS has a central plate residing in a second plane and at least two port tabs spaced apart from one another and extending from the central plate. The substrate has a central portion that defines a mesh structure between the base electrode and the central plate of the multi-port signal structure. A plurality of magnetic pillars are provided within the mesh structure, wherein each of the plurality of the magnetic pillars are spaced apart from one another and surrounded by a corresponding portion of the mesh structure. The PMD may provide a magnetically self-biased device that may be used as a radio frequency (RF) circulator, an RF isolator, and the like.
FILED Wednesday, January 15, 2020
APPL NO 16/743367
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/015 (20130101)
H01F 1/22 (20130101)
H01F 1/36 (20130101)
H01F 3/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/02 (20130101) Original (OR) Class

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/36 (20130101)
H01P 1/38 (20130101)
H01P 1/387 (20130101)

Transmission
H04B 7/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854923 Xu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Wu Xu (Richland, Washington);  Shuru Chen (Troy, Michigan);  Ji-Guang Zhang (Richland, Washington);  Xia Cao (Richland, Washington);  Haiping Jia (Richland, Washington);  Bin Liu (Richland, Washington);  Xiaodi Ren (Richland, Washington)
ABSTRACT Low flammability and nonflammable localized superconcentrated electrolytes (LSEs) for stable operation of lithium and sodium ion batteries are disclosed. Electrochemical devices including the low flammability and nonflammable LSEs are also disclosed. The low flammability and nonflammable LSEs include an active salt, a solvent comprising a flame retardant compound, wherein the active salt is soluble in the solvent, and a diluent in which the active salt is insoluble or poorly soluble. The LSE may further include a cosolvent, such as a carbonate, a sulfone, a sulfite, a sulfate, a carboxylate, an ether, a nitrogen-containing solvent, or any combination thereof. In certain embodiments, such as when the solvent and diluent are immiscible, the LSE further includes a bridge solvent.
FILED Friday, August 31, 2018
APPL NO 16/119641
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/382 (20130101)
H01M 10/052 (20130101)
H01M 10/0567 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101) Original (OR) Class
H01M 10/4235 (20130101)
H01M 2300/0034 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854932 Ganguli et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Anurag Ganguli (Milpitas, California);  Julian Schwartz (Palo Alto, California);  Ajay Raghavan (Mountain View, California);  Peter Kiesel (Palo Alto, California);  Bhaskar Saha (Redwood City, California);  Saroj Sahu (Fremont, California);  Lars Wilko Sommer (Bretten, Germany)
ABSTRACT A system includes a first optical sensor sensitive to both a parameter of interest, Parameter1, and at least one confounding parameter, Parameter2 and a second optical sensor sensitive only to the confounding parameter. Measurement circuitry measures M1 in response to light scattered by the first optical sensor, where M1=value of Parameter1+K*value of Parameter2. The measurement circuitry also measures M2 in response to light scattered by the second optical sensor, where M2=value of Parameter2. Compensation circuitry determines a compensation factor, K, for the confounding parameter based on measurements of M1 and M2 taken over multiple load/unload cycles or over one or more thermal cycles. The compensation factor is used to determine the parameter of interest.
FILED Tuesday, July 28, 2015
APPL NO 14/810919
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 3/036 (20130101)
G01D 5/353 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/392 (20190101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/48 (20130101)
H01M 10/425 (20130101)
H01M 10/486 (20130101)
H01M 10/4285 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855203 Maksimovic et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado);  Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado);  Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Dragan Maksimovic (Boulder, Colorado);  Prasanta Achanta (San Jose, California);  Brian B. Johnson (Denver, Colorado);  Miguel Rodriguez (Golden, Colorado);  Vahan Gevorgian (Westminster, Colorado)
ABSTRACT A cascaded architecture composed of interconnected blocks that are each designed to process constant power and eliminate bulk energy storage are provided. Further, local controls within each block natively achieve both block- and system-level aims, making the system modular and scalable. Further methods of providing power conversion using such interconnected clocks are also provided.
FILED Thursday, May 02, 2019
APPL NO 16/402222
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/4826 (20130101)
H02M 7/53875 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855259 Panas et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert Matthew Panas (Dublin, California);  Logan Bekker (Pleasanton, California);  Julie Mancini (Livermore, California);  Andrew Pascall (Livermore, California);  Jonathan Hopkins (Los Angeles, California);  Amin Farzaneh (Woodland Hills, California)
ABSTRACT The present disclosure relates to a micromechanical displacement logic, signal propagation system that makes use of first and second bistable elements, and first and second mounting structures arranged adjacent opposing surfaces of the first bistable element. A plurality of pivotal lever arms are used to support the first bistable element in either one of two positions of equilibrium. A support structure and a compressible flexure element disposed between the support structure and the first mounting structure apply a preload force to the first mounting structure, which imparts the preload force to the first bistable element. The first bistable element is moveable from one of the two stable equilibrium positions to the other in response to an initial signal applied thereto. The preload force, at least one stiffness characteristic of the lever arms, and a compressibility of a compressible coupling element which links the second bistable element to the first, are all selected to tune signal propagation from the first bistable element to the second bistable element.
FILED Wednesday, March 04, 2020
APPL NO 16/808629
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0097 (20130101)
B81B 2201/0292 (20130101)

Pulse Technique
H03K 3/013 (20130101)
H03K 3/0375 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855706 Choudhury et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Sutanay Choudhury (Kennewick, Washington);  Khushbu Agarwal (Kennewick, Washington);  Pin-Yu Chen (Yorktown Heights, New York);  Indrajit Ray (Fort Collins, Colorado)
ABSTRACT A method for securing an IT (information technology) system using a set of methods for knowledge extraction, event detection, risk estimation and explanation for ranking cyber-alerts which includes a method to explain the relationship (or an attack pathway) from an entity (user or host) and an event context to another entity (a high-value resource) and an event context (attack or service failure).
FILED Wednesday, October 11, 2017
APPL NO 15/730028
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 16/9024 (20190101)
G06F 21/566 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/0427 (20130101)
G06N 3/0445 (20130101)
G06N 5/022 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/20 (20130101)
H04L 63/1416 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
H04L 63/1441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10856376 Song et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Lumileds LLC (San Jose, California)
ASSIGNEE(S) Lumileds LLC (San Jose, California)
INVENTOR(S) Zhihua Song (San Jose, California);  Wouter Soer (San Jose, California);  Ron Bonne (San Jose, California);  Yifeng Qiu (San Jose, California)
ABSTRACT A light emitting diode (LED) module may include a direct current (DC) voltage node formed on a first layer. The DC voltage node may be configured to sink a first current. One or more devices may be formed on the first layer configured to provide a second current to one or more LEDs. A device of the one or more devices may carry a steep slope voltage waveform. A local shielding area may be formed in a second layer directly below the DC voltage node and the one or more devices. The local shielding area may include a substantially continuous area of conductive material. A conductive via may extend through one or more layers. The conductive via may electrically connect the DC voltage node and the local shielding area.
FILED Thursday, November 08, 2018
APPL NO 16/184565
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 25/50 (20130101)
H01L 25/167 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/6591 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 45/10 (20200101) Original (OR) Class
H05B 45/37 (20200101)
H05B 45/50 (20200101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/024 (20130101)
H05K 1/053 (20130101)
H05K 1/056 (20130101)
H05K 1/111 (20130101)
H05K 1/115 (20130101)
H05K 1/181 (20130101)
H05K 1/0203 (20130101)
H05K 1/0215 (20130101)
H05K 1/0224 (20130101)
H05K 1/0243 (20130101)
H05K 1/0251 (20130101)
H05K 1/0262 (20130101)
H05K 3/16 (20130101)
H05K 3/44 (20130101)
H05K 3/0061 (20130101)
H05K 3/107 (20130101)
H05K 3/146 (20130101)
H05K 3/181 (20130101)
H05K 3/303 (20130101)
H05K 3/465 (20130101)
H05K 3/467 (20130101)
H05K 3/4076 (20130101)
H05K 3/4608 (20130101)
H05K 3/4644 (20130101)
H05K 3/4661 (20130101)
H05K 3/4679 (20130101)
H05K 3/4688 (20130101)
H05K 9/0084 (20130101)
H05K 9/0088 (20130101)
H05K 13/00 (20130101)
H05K 2201/066 (20130101)
H05K 2201/093 (20130101)
H05K 2201/0723 (20130101)
H05K 2201/09327 (20130101)
H05K 2201/09563 (20130101)
H05K 2201/10106 (20130101)
H05K 2201/10166 (20130101)
H05K 2201/10522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10850395 Moses et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Melanie E. Moses (Albuquerque, New Mexico);  Joshua P. Hecker (Albuquerque, New Mexico);  Qi Lu (Albuquerque, New Mexico)
ABSTRACT Teams of robots can be organized to collectively complete complex real-world tasks, for example collective foraging in which robots search for, pick up, and drop off targets in a collection zone. A dynamic multiple-place foraging algorithm (MPFAdynamic) is a scalable, flexible, and efficient algorithm for robot swarms to collect objects in unmapped environments. It achieves scalability through a decentralized architecture in which robots search without central control, and then return to mobile depots which provide collection and communication points. Mobile depots move closer to clusters of targets as robots discover them, which reduces robot transport time as well as collisions among robots. Flexibility is achieved by incorporating individual robot behaviors in which robots move and communicate in ways that mimic the foraging behaviors of ants. The MPFAdynamic algorithm demonstrates that dispersed agents that dynamically adapt to local information in their environment provide more flexible and scalable swarms.
FILED Monday, May 21, 2018
APPL NO 15/985213
ART UNIT 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0084 (20130101)
B25J 9/162 (20130101)
B25J 9/1666 (20130101) Original (OR) Class
B25J 9/1676 (20130101)
B25J 11/008 (20130101)
B25J 19/02 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/39146 (20130101)
G05B 2219/39168 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0088 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852485 Stone et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Stone Aerospace, Inc. (Del Valle, Texas)
ASSIGNEE(S) Stone Aerospace, Inc. (Del Valle, Texas)
INVENTOR(S) William C. Stone (Del Valle, Texas);  Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT An optical energy transfer and conversion system comprising a fiber spooler and an electrical power extraction subsystem connected to the spooler with an optical waveguide. Optical energy is generated at and transferred from a base station through fiber wrapped around the spooler, and ultimately to the power extraction system at a remote mobility platform for conversion to another form of energy. The fiber spooler may reside on the remote mobility platform which may be a vehicle, or apparatus that is either self-propelled or is carried by a secondary mobility platform either on land, under the sea, in the air or in space.
FILED Monday, January 15, 2018
APPL NO 15/871774
ART UNIT 2883 — Optics
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 33/00 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 41/0085 (20130101)
E21B 47/135 (20200501)

Optical Elements, Systems, or Apparatus
G02B 6/3604 (20130101) Original (OR) Class
G02B 6/4268 (20130101)
G02B 6/4296 (20130101)
G02B 6/4415 (20130101)
G02B 6/4436 (20130101)
G02B 6/4458 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/30 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/30 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10852754 Piraner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Alexander Piraner (Long Beach, California);  Son T. Vo (Huntington Beach, California);  Wayne Pauley (Seal Beach, California)
ABSTRACT A pressure control system may include a plurality of inflatable objects, each of the inflatable objects having a respective pressure sensor and a respective inflation valve, wherein each of the inflation valves has a behavior profile predictive of an amount of current used by the valve when operated. A valve controller of the system may have a pressure management circuit that receives information from the pressure sensors and is configured to automatically maintain a respective selected pressure in each of the inflatable objects by issuing commands to operate the inflation valves. An electrical current management circuit of the valve controller may be configured to predict, based on the valve behavior profiles, what effect the command would have on a total current usage, when executed, and automatically prevent any command that would cause the total current usage to exceed a maximum allowable current.
FILED Tuesday, July 25, 2017
APPL NO 15/659558
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/62 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 31/0675 (20130101)
F16K 37/005 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 16/2026 (20130101) Original (OR) Class

Pulse Technique
H03K 19/177 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10849895 Bassaganya-Riera et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Landos Biopharma, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) LANDOS BIOPHARMA, INC. (Blacksburg, Virginia)
INVENTOR(S) Josep Bassaganya-Riera (Blacksburg, Virginia);  Adria Carbo Barrios (Blacksburg, Virginia);  Richard Gandour (Blacksburg, Virginia);  Julian D. Cooper (Blacksburg, Virginia);  Raquel Hontecillas (Blacksburg, Virginia)
ABSTRACT Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including infectious disease, autoimmune disease, diabetes, and a chronic inflammatory disease.
FILED Monday, May 04, 2020
APPL NO 16/866169
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/423 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)

Acyclic or Carbocyclic Compounds
C07C 65/40 (20130101)

Heterocyclic Compounds
C07D 213/69 (20130101)
C07D 213/79 (20130101)
C07D 307/60 (20130101)
C07D 307/68 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 403/14 (20130101)
C07D 413/12 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10851627 Hale et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Fall River, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Fall River, Massachusetts)
INVENTOR(S) Mike Hale (Hopewell Junction, New York);  Keith Hale (Hopewell Junction, New York);  Melinda Sims (Lakeland, Florida)
ABSTRACT A system for extracting landfill gas from a landfill is provided. According to some embodiments, a control system for landfill gas extraction is provided. The control system uses a throttle to control flow of landfill gas extracted from the landfill. The throttle is actuated in use to vary the flow of gas between a well and a gas collection system, in accordance with a control algorithm that adjusts flow as a parameter in controlling gas extraction. The throttle is configured to ensure that there is at least some flow of landfill gas from the landfill to a gas output throughout operation. The extraction system provides an efficient system for landfill gas extraction, while mitigating a risk of creating undesired or unpleasant conditions and/or of violating regulations during operation.
FILED Friday, July 12, 2019
APPL NO 16/510167
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/006 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/12 (20130101) Original (OR) Class

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/36 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/30 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/30 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10855376 Morton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Morton Photonics (West Friendship, Maryland)
ASSIGNEE(S) Morton Photonics (West Friendship, Maryland)
INVENTOR(S) Paul A. Morton (West Friendship, Maryland);  Jacob Khurgin (Pikesville, Maryland)
ABSTRACT The present invention reduces the level of optical reflections created in a photonic integrated circuit (PIC) going back into an integrated laser through Reflection Engineering; optimizing the phase/timing and position of optical reflections inherent to a PIC design while adding engineered reflections to the PIC to allow inherent reflections to be reduced or eliminated. The Wavelength Division Multiplexed (WDM) geometric optical isolator of the present invention combines an array of closely spaced WDM lasers with an array of modulators in a novel geometry in order to provide effective optical isolation of the lasers.
FILED Thursday, January 30, 2020
APPL NO 16/777131
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/00 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/2676 (20130101)

Transmission
H04B 10/40 (20130101) Original (OR) Class
H04B 10/50 (20130101)
H04B 10/516 (20130101)
H04B 10/25759 (20130101)
H04B 2210/006 (20130101)

Selecting
H04Q 5/00 (20130101)
H04Q 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10851393 San et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Ka-Yiu San (Houston, Texas);  Xian Zhang (Houston, Texas);  Hui Wu (Houston, Texas);  Dan Wang (Houston, Texas)
ABSTRACT The present disclosure describes a genetically engineered a KASIII-independent fatty acid biosynthetic pathway that makes use of the promiscuous nature of the rest of the FAS enzymes (3-ketoacyl-ACP synthetase, 3-ketoacyl-ACP reductase, 3-hydroxyacyl ACP dehydrase, enoyl-ACP reductase) to bypass the KASIII step by providing a Co-A precursor of two or higher than two carbons (such as the four carbon butyryl-CoA) as the starting molecule. Since many CoA-based starter molecules can be supplied for the fatty acid synthesis, much more diversified products can be obtained with various carbon-chain lengths. As such, this disclosure will serve as a powerful and efficient platform to produce low to medium chain length products carrying many different functional groups.
FILED Monday, February 22, 2016
APPL NO 15/553129
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 9/0006 (20130101)
C12N 9/13 (20130101)
C12N 9/16 (20130101)
C12N 9/88 (20130101)
C12N 9/1029 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/6409 (20130101) Original (OR) Class
C12P 7/6463 (20130101)

Enzymes
C12Y 101/011 (20130101)
C12Y 103/01009 (20130101)
C12Y 203/01041 (20130101)
C12Y 208/03008 (20130101)
C12Y 301/02014 (20130101)
C12Y 402/01017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP32535 Weber
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Courtney A. Weber (Geneva, New York)
ABSTRACT This invention relates to a new and distinct June-bearing (short day responsive) strawberry plant named ‘Dickens’ primarily adapted to the growing conditions of the west central New York and other regions of similar climate. The new plant is primarily characterized by strong vigor, high resistance to replant diseases, fruit equally broad and long, wide rounded conical fruit shape, large primary fruit with a small internal cavity, uniformly large secondary and tertiary fruit, high fruit numbers per fruiting lateral and plant, flat calyx and intense red fruit color externally and internally.
FILED Thursday, August 01, 2019
APPL NO 16/602080
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/7409 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10849395 Aubin et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of Washington (Seattle, Washington);  The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Washington (Seattle, Washington);  The United States as represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Patrick M. Aubin (Seattle, Washington);  Chris Richburg (Seattle, Washington);  Joseph Czerniecki (Seattle, Washington);  Evan Schuster (Seattle, Washington)
ABSTRACT Several embodiments are provided of a device which is tunable for providing a walking aid user with passive haptic feedback. The haptic feedback is provided to the user when a predetermined, desired force in the device is reached. The force, often simply an axial force, in the device is inputted by the user, who is looking to support some of his or her body weight, thereby taking some weight off of one or both legs for some purpose. The amount of body weight support the user would input is often expressed in terms of percentage of the user's total body weight, and can therefore be predetermined and the device tuned accordingly.
FILED Friday, April 20, 2018
APPL NO 15/958947
ART UNIT 3636 — Static Structures, Supports and Furniture
CURRENT CPC
Walking Sticks; Umbrellas; Ladies\' or Like Fans
A45B 3/00 (20130101)
A45B 9/04 (20130101) Original (OR) Class
A45B 2200/05 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 3/02 (20130101)
A61H 3/0288 (20130101)
A61H 2201/0184 (20130101)
A61H 2201/1207 (20130101)
A61H 2201/1246 (20130101)
A61H 2201/1657 (20130101)
A61H 2201/5061 (20130101)
A61H 2201/5071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10849896 Patel et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of South Florida (Tampa, Florida);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Niketa A. Patel (Land O'Lakes, Florida);  Robert Pleasants Sparks (Tampa, Florida);  Wayne Charles Guida (St. Petersburg Beach, Florida)
ABSTRACT Various scaffolds of small molecules capable of binding to the active site of sortilin are identified by in silico methods. These scaffolds include norbornene anhydride amino acid adducts and 2-substituted 3-oxo-1,2,3,4-tetrahydro-2-quinoxalines. These sortilin ligands increase the uptake of glucose in 3T3L1 cells and can be employed in compositions to increase uptake of glucose for the treatment of diabetic patents.
FILED Friday, June 29, 2018
APPL NO 16/022803
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/197 (20130101)
A61K 31/498 (20130101) Original (OR) Class
A61K 31/4035 (20130101)
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 35/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10853073 Fleming, Jr. et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Kermin E. Fleming, Jr. (Hudson, Massachusetts);  Ping Zou (Westborough, Massachusetts);  Mitchell Diamond (Shrewsbury, Massachusetts);  Benjamin Keen (Marlborough, Massachusetts)
ABSTRACT Systems, methods, and apparatuses relating to conditional operations in a configurable spatial accelerator are described. In one embodiment, a hardware accelerator includes an output buffer of a first processing element coupled to an input buffer of a second processing element via a first data path that is to send a first dataflow token from the output buffer of the first processing element to the input buffer of the second processing element when the first dataflow token is received in the output buffer of the first processing element; an output buffer of a third processing element coupled to the input buffer of the second processing element via a second data path that is to send a second dataflow token from the output buffer of the third processing element to the input buffer of the second processing element when the second dataflow token is received in the output buffer of the third processing element; a first backpressure path from the input buffer of the second processing element to the first processing element to indicate to the first processing element when storage is not available in the input buffer of the second processing element; a second backpressure path from the input buffer of the second processing element to the third processing element to indicate to the third processing element when storage is not available in the input buffer of the second processing element; and a scheduler of the second processing element to cause storage of the first dataflow token from the first data path into the input buffer of the second processing element when both the first backpressure path indicates storage is available in the input buffer of the second processing element and a conditional token received in a conditional queue of the second processing element from another processing element is a first value.
FILED Saturday, June 30, 2018
APPL NO 16/024849
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3005 (20130101)
G06F 9/3836 (20130101)
G06F 9/5027 (20130101)
G06F 9/30072 (20130101) Original (OR) Class
G06F 15/825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854768 Zeng et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Xiaoge Zeng (Palo Alto, California);  Zhihong Huang (Palo Alto, California);  Di Liang (Santa Barbara, California)
ABSTRACT A three-terminal avalanche photodiode provides a first controllable voltage drop across a light absorbing region and a second, independently controllable, voltage drop across a photocurrent amplifying region. The absorbing region may also have a different composition from the amplifying region, allowing further independent optimization of the two functional regions. An insulating layer blocks leakage paths, redirecting photocurrent toward the region(s) of highest avalanche gain. The resulting high-gain, low-bias avalanche photodiodes may be fabricated in integrated optical circuits using commercial CMOS processes, operated by power supplies common to mature computer architecture, and used for optical interconnects, light sensing, and other applications.
FILED Thursday, December 20, 2018
APPL NO 16/226753
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/44 (20130101)
G01J 2001/4466 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/1075 (20130101) Original (OR) Class
H01L 31/1804 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 10855440 Alwen et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Wickr Inc. (San Francisco, California)
ASSIGNEE(S) Wickr Inc. (Pleasanton, California)
INVENTOR(S) Joël Alwen (Vienna, Austria);  Thomas Michael Leavy (River Edge, New Jersey)
ABSTRACT The present application describes a method, system, and non-transitory computer-readable medium for generating new keys during a secure communication session. A key derivation function is operatively connected to both a counter and a memory. The key derivation function generates new key material from a first input and a second input in response to a signal provided by the counter. The key derivation function generates the new key material and outputs it to the memory.
FILED Wednesday, November 08, 2017
APPL NO 15/806471
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/00 (20130101) Original (OR) Class
H04L 9/0816 (20130101)
H04L 9/0819 (20130101)
H04L 9/0838 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10852123 Stavis et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Samuel Martin Stavis (Rockville, Maryland);  Craig Robert Copeland (Joppa, Maryland)
ABSTRACT Performing critical-dimension localization microscopy includes: subjecting a first dimensional member and a second dimensional member of a reference artifact to critical-dimension metrology, the first and second dimensional members, in combination, including a critical dimension and each independently providing optical contrast; determining a primary length of the critical dimension to be traceable to International System of Units meter; imaging in a calibrant optical field, by optical microscopy, the first dimensional member and the second dimensional member, the calibrant optical field disposed in an ocular optical field; determining, from the optical microscopy of the first dimensional member and the second dimensional member, a secondary length and a secondary length uncertainty of the critical dimension subjected to the critical-dimension metrology; and calibrating the calibrant optical field and the secondary length, to the primary length to establish traceability of the secondary length to the International System of Units meter to perform critical-dimension localization microscopy.
FILED Friday, October 25, 2019
APPL NO 16/663959
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/022 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/62 (20170101)
G06T 2207/10056 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 10854316 Marciano et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
APPLICANT(S) Michael Marciano (Manlius, New York);  Jonathan D. Adelman (Mexico, New York);  Laura C. Haarer (Jamesville, New York)
ASSIGNEE(S) Syracuse University (Syracuse, New York)
INVENTOR(S) Michael Marciano (Manlius, New York);  Jonathan D. Adelman (Mexico, New York);  Laura C. Haarer (Jamesville, New York)
ABSTRACT A system configured to characterize a ratio of contributors to a DNA mixture within a sample, the system including: a sample preparation module configured to generate initial data about the DNA mixture within the sample; a processor comprising a ratio of contributors determination module configured to: (i) receive the generated initial data; (ii) analyze the generated initial data to determine the ratio of contributors to the DNA mixture within the sample; and an output device configured to receive the determined ratio of contributors from the processor, and further configured to output information about the received determined ratio of contributors.
FILED Friday, December 02, 2016
APPL NO 15/367814
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 30/00 (20190201) Original (OR) Class
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 10850550 Rich et al.
FUNDED BY
Department of the Treasury (TREASURY)
Bureau of Engraving and Printing (BEP)
APPLICANT(S) Wavefront Technology, Inc. (Paramount, California)
ASSIGNEE(S) WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
INVENTOR(S) Christopher Chapman Rich (Rancho Palos Verdes, California);  Joel Mikael Petersen (Valley Village, California);  Roger Winston Phillips (Santa Rosa, California);  John Michael Tamkin (Pasadena, California)
ABSTRACT A security device includes an array of lenses and a plurality of first and second segments disposed under the array of lenses. At a first viewing angle, the array of lenses presents a first image for viewing without presenting the second image for viewing, and at a second viewing angle different from the first viewing angle, the array of lenses presents for viewing the second image without presenting the first image for viewing. At least one first or second segment can include one or more microstructures or one or more nanostructures configured to produce one or more colors for the first or second image.
FILED Tuesday, April 18, 2017
APPL NO 15/490639
ART UNIT 2872 — Optics
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/08 (20130101)
B32B 3/30 (20130101)
B32B 7/06 (20130101)
B32B 27/08 (20130101)
B32B 27/32 (20130101)
B32B 27/36 (20130101)
B32B 27/285 (20130101)
B32B 27/302 (20130101)
B32B 27/304 (20130101)
B32B 27/365 (20130101)
B32B 2250/24 (20130101)
B32B 2255/20 (20130101)
B32B 2255/26 (20130101)
B32B 2255/28 (20130101)
B32B 2255/205 (20130101)
B32B 2307/40 (20130101)
B32B 2307/41 (20130101)
B32B 2307/204 (20130101)
B32B 2307/402 (20130101)
B32B 2307/408 (20130101)
B32B 2307/412 (20130101)
B32B 2307/422 (20130101)
B32B 2307/732 (20130101)
B32B 2307/4023 (20130101)
B32B 2307/4026 (20130101)
B32B 2425/00 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/21 (20141001)
B42D 25/324 (20141001)
B42D 25/328 (20141001)
B42D 25/351 (20141001) Original (OR) Class
B42D 25/373 (20141001)
B42D 25/378 (20141001)

Special Designs or Pictures
B44F 1/045 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0056 (20130101)
G02B 27/06 (20130101)
G02B 30/27 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10854586 Dennis et al.
FUNDED BY
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronics Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Lori D. Dennis (Centreville, Virginia);  Jamie A. Bernard (Midland, Virginia);  Alan F. Dennis (Centreville, Virginia);  Jane O. Gilliam (Centreville, Virginia);  Jason F. Ross (Haymarket, Virginia);  Keith K. Sturcken (Nokesville, Virginia);  Dale A Rickard (Manassas, Virginia)
ABSTRACT A multi-chip module hybrid integrated circuit (MCM-HIC) provides cold spare support to an apparatus comprising a plurality of ICs and/or other circuits that are not cold spare compliant. At least one core IC and at least one cold spare chiplet are installed on an interconnecting substrate having a plurality of power zones to which power can be applied and withdrawn as needed. When powered, the cold spare chiplets serve as mediators and interfaces between the non cold spare compliant circuits. When the cold spare chiplets are at least partly unpowered, they protect all interconnected circuits, and ensure that interconnected circuits that remain powered are not hindered by unpowered interconnected circuits. Cold spare chiplets can extend across boundaries between power zones. External circuits can be exclusively interfaced to a subset of the power zones. Separate power circuits within a power zone can be sequenced during application and withdrawal of power.
FILED Friday, May 24, 2019
APPL NO 16/422072
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/64 (20130101)
H01L 23/3675 (20130101)
H01L 23/5385 (20130101)
H01L 23/49811 (20130101)
H01L 24/16 (20130101)
H01L 24/32 (20130101)
H01L 24/73 (20130101)
H01L 25/50 (20130101)
H01L 25/165 (20130101) Original (OR) Class
H01L 2224/16225 (20130101)
H01L 2224/32221 (20130101)
H01L 2224/73253 (20130101)
H01L 2924/19105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10854929 Bhavaraju et al.
FUNDED BY
APPLICANT(S) FIELD UPGRADING USA, INC. (Broomfield, Colorado)
ASSIGNEE(S) FIELD UPGRADING USA, INC. (Broomfield, Colorado)
INVENTOR(S) Sai Bhavaraju (West Jordan, Utah);  Mathew Robins (Saratoga Springs, Utah);  Alexis Eccleston (Midvale, Utah)
ABSTRACT An intermediate temperature sodium-halogen secondary cell that includes a negative electrode compartment housing a negative, molten sodium-based electrode and a positive electrode compartment housing a current collector disposed in a highly conductive molten positive electrolyte. A sodium halide (NaX) positive electrode is disposed in a molten positive electrolyte comprising one or more AlX3 salts, wherein X may be the same or different halogen selected from Cl, Br, and I, wherein the ratio of NaX to AlX3 is greater than or equal to one. A sodium ion conductive solid electrolyte membrane separates the molten sodium negative electrode from the molten positive electrolyte. The secondary cell operates at a temperature in the range from about 80° C. to 210° C.
FILED Tuesday, December 01, 2015
APPL NO 14/956078
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/40 (20130101)
H01M 4/62 (20130101)
H01M 4/381 (20130101)
H01M 4/388 (20130101)
H01M 4/661 (20130101)
H01M 10/36 (20130101)
H01M 10/054 (20130101)
H01M 10/399 (20130101) Original (OR) Class
H01M 10/0562 (20130101)
H01M 10/0563 (20130101)
H01M 10/4235 (20130101)
H01M 2300/0054 (20130101)
H01M 2300/0068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 01, 2020.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201201.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital