FedInvent™ Patents
Patent Details for Tuesday, December 08, 2020
This page was updated on Monday, March 27, 2023 at 06:14 AM GMT
Department of Health and Human Services (HHS)
| US 10856760 | Narayan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); TOPERA, INC. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sanjiv M. Narayan (Palo Alto, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | A system for processing cardiac activation information associated with a complex rhythm disorder identifies a location of the heart rhythm disorder by determining activations within cardiac signals obtained at neighboring locations of the heart and arranging the activations to identify an activation trail. The activation trail may define a rotational pattern or radially emanating pattern corresponding to an approximate core of the heart rhythm disorder. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/649494 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0255 (20130101) A61B 5/0422 (20130101) A61B 5/0432 (20130101) A61B 5/0452 (20130101) Original (OR) Class A61B 5/0456 (20130101) A61B 5/0464 (20130101) A61B 5/0472 (20130101) A61B 5/726 (20130101) A61B 5/04011 (20130101) A61B 5/04012 (20130101) A61B 5/4857 (20130101) A61B 5/6852 (20130101) A61B 5/7221 (20130101) A61B 5/7264 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856806 | Iskander et al. |
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| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Magdy F. Iskander (Honolulu, Hawaii); Ruthsenne R. G. Perron (Waipahu, Hawaii) |
| ABSTRACT | A system and method for monitoring lung water content of a patient. The system may include at least two microwave sensors and a processor. The system may transmit one or more microwave signals into the thorax of a patient using one or more of the microwave sensors. The system may then receive one or more of the microwave signals using one or more of the microwave sensors. The one or more received microwave signals may each have at least one associated frequency component with a magnitude and a phase. The system may analyze the phase of one or more received microwave signals to monitor changes in the lung water content. The system may analyze the magnitude of one or more received microwave signals to determine whether the lung water content is increasing or decreasing. |
| FILED | Monday, August 17, 2015 |
| APPL NO | 14/828323 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/08 (20130101) A61B 5/021 (20130101) A61B 5/024 (20130101) A61B 5/029 (20130101) A61B 5/0205 (20130101) A61B 5/0507 (20130101) A61B 5/0809 (20130101) A61B 5/0816 (20130101) A61B 5/4878 (20130101) Original (OR) Class A61B 5/6823 (20130101) A61B 5/7246 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) A61B 5/7282 (20130101) A61B 2560/0223 (20130101) A61B 2562/0228 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856818 | Tian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Xiaoyu Tian (Durham, North Carolina); Ehsan Samei (Durham, North Carolina); Paul Segars (Durham, North Carolina) |
| ABSTRACT | Systems and methods for estimating irradiation dose for patient application based on a radiation field model and a patient anatomy model are disclosed. According to an aspect, a method includes providing a database of patient anatomy models. The method also includes providing a radiation field model of an X-ray system. Further, the method includes receiving a measure of an anatomy of a patient. The method also includes determining a patient anatomy model among the patient anatomy models that matches or is similar to the anatomy of the patient based on the measure of the patient and a corresponding measure of each of the patient anatomy models. The method also includes estimating an irradiation dose for application to the patient by the X-ray system based on the radiation field model and the determined patient anatomy model. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/531730 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Original (OR) Class A61B 6/50 (20130101) A61B 6/544 (20130101) A61B 6/545 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857036 | Peli et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Eliezer Peli (Boston, Massachusetts); Jae-Hyun Jung (Boston, Massachusetts) |
| ABSTRACT | The disclosure features systems and methods for providing information to a user about the user's environment. The systems feature a detection apparatus configured to obtain image information about the environment, where the image information corresponds to information at multiple distances relative to a position of the user within the environment, and an electronic processor configured to obtain focal plane distance information defining a set of one or more distance values relative to the position of the user within the environment, construct one or more confocal images of the environment from the image information and the set of one or more distance values, wherein each of the one or more confocal images corresponds to a different distance value and includes a set of pixels, and transform the one or more confocal images to form one or more representative images having fewer pixels and a lower dynamic range. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/183930 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Original (OR) Class Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/061 (20130101) A61H 2003/063 (20130101) A61H 2201/165 (20130101) A61H 2201/5038 (20130101) A61H 2201/5048 (20130101) A61H 2201/5084 (20130101) A61H 2201/5092 (20130101) A61H 2201/5097 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/36046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857112 | Jackson et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Travis Corey Jackson (Pittsburgh, Pennsylvania); Jonathan C. Verrier (Pittsburgh, Pennsylvania); Patrick Kochanek (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of treating a cellular injury in a subject comprising administering to a subject in need thereof, a therapeutically effective amount of a compound of formula I: wherein at least one of R1-R8 is a sulfonic acid, a carboxylic acid, a phosphonic acid, a pharmaceutically acceptable salt of a sulfonic acid, a pharmaceutically acceptable salt of a carboxylic acid, a pharmaceutically acceptable salt of a phosphonic acid, a sulfonate ester, a carboxylate acid ester, or a phosphonate ester; and the remaining R1-R8 are each independently selected from hydrogen, halo, hydroxyl, nitro, nitroso, amino, substituted amino, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoy, alkenyloxy, substituted alkenyloxy, alkynyloxy, substituted alkynyloxy, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, cycloalkynyl, substituted cycloalkynyl, cycloalkyloxy, substituted cycloalkyloxy, heterocyclyl, substituted heterocyclyl, heterocyclyloxy, substituted heterocyclyloxy, heterocyclylthio, substituted heterocyclylthio, cyano, acyl, acylamino, acyloxy, aminocarbonyl, aminocarbonylamino, aminothiocarbonylamino, aminocarbonyloxy, aminosulfonyl, sulfonylamino, aryl, substituted aryl, aryloxy, substituted aryloxy, arylthio, substituted arylthio, alkylthio, substituted alkylthio, cycloalkylthio, substituted cycloalkylthio, cycloalkenylthio, substituted cycloalkenylthio, thiol, heteroaryl, substituted heteroaryl, heteroaryloxy, substituted heteroaryloxy, heteroarylthio, substituted heteroarylthio, sulfonyl, or sulfonyloxy. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 15/448337 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/52 (20130101) A61K 31/167 (20130101) A61K 31/185 (20130101) Original (OR) Class A61K 31/185 (20130101) A61K 31/192 (20130101) A61K 31/551 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4418 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857130 | Wandinger-Ness et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Angela Wandinger-Ness (Albuquerque, New Mexico); Laurie Hudson (Albuquerque, New Mexico); Larry Sklar (Albuquerque, New Mexico); Zurab Surviladze (Albuquerque, New Mexico); Tudor Oprea (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to molecules which function as modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases (e.g. Rac, Cdc42 and Rho GTPases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-B cell lymphoma, where these GTPases are overexpressed or hyperactivated), sporadic and genetic diseases where activation of Rho GTPases plays a pivotal role (Menkes disease, rheumatoid arthritis, atherosclerosis, diabetes (type I), Huntington's disease and Alzheimer's disease) which are mediated through these proteins. Compounds according to the present invention may also be used as a therapy for the treatment of Entamoeba spp. or Acanthamoeba spp. infections, especially including Entamoeba histolytica. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/445413 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) A61K 31/407 (20130101) Original (OR) Class A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 231/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857139 | Jung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael E. Jung (Los Angeles, California); Charles L. Sawyers (New York, New York); Samedy Ouk (Los Angeles, California); Chris Tran (New York, New York); John Wongvipat (New York, New York) |
| ABSTRACT | Provided herein are compounds and pharmaceutical compositions including the compound having a formula: These compounds are androgen receptor modulators useful for the treatment of androgen receptor-associated conditions. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969147 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 31/4439 (20130101) Original (OR) Class Heterocyclic Compounds C07D 401/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857140 | McCormick et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); LEIDOS BIOMEDICAL RESEARCH, INC. (Frederick, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Leidos Biomedical Research, Inc. (Frederick, Maryland) |
| INVENTOR(S) | Frank McCormick (San Francisco, California); Adam R. Renslo (Oakland, California); David Turner (Frederick, Maryland); Stephan Gysin (Basel, Switzerland); Anna E. Maciag (Frederick, Maryland); Oleg Chertov (Frederick, Maryland) |
| ABSTRACT | Provided herein, inter alia, are methods and compounds of formula (I) for inhibiting K-Ras and for treating cancer. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/571475 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) Original (OR) Class A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 207/16 (20130101) C07D 211/28 (20130101) C07D 211/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857161 | McCall et al. |
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| FUNDED BY |
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| APPLICANT(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Kanneboyina Nagaraju (Columbia, Maryland) |
| ABSTRACT | Provided herein is a pharmaceutical composition comprising a compound having the structural formula wherein the compound is present in an amount effective to treat or reduce the symptoms of muscular dystrophy. The therapeutically effective amount may be between 10 mg to 200 mg, or may be between 0.01 mg/kg to 10.0 mg/kg. Also provided are methods of treating or reducing the symptoms of muscular dystrophy, comprising the administration, to a patient in need thereof, of a therapeutically effective of the above compound. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/226061 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/573 (20130101) Original (OR) Class A61K 31/575 (20130101) Steroids C07J 5/0038 (20130101) C07J 5/0053 (20130101) C07J 5/0076 (20130101) Technologies for Adaptation to Climate Change Y02A 50/479 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/824 (20130101) Y10S 514/825 (20130101) Y10S 514/826 (20130101) Y10S 514/903 (20130101) Y10S 514/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857165 | Ebetino et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); BioVinc LLC (Pasadena, California); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Los Angeles, California); BioVinc LLC (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Frank Hallock Ebetino (Venice, Florida); Ichiro Nishimura (Venice, California); Shuting Sun (Temple City, California); Mark Walden Lundy (Cincinnati, Ohio); Akishige Hokugo (Los Angeles, California); Charles McKenna (Pacific Palisades, California); Keivan Sadrerafi (Pasadena, California) |
| ABSTRACT | Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 16/099227 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 31/663 (20130101) Original (OR) Class A61K 31/675 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/58 (20130101) C07F 9/6506 (20130101) C07F 9/6561 (20130101) C07F 9/65583 (20130101) C07F 9/65586 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857167 | Morrow et al. |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| INVENTOR(S) | Ardythe L. Morrow (Cincinnati, Ohio); Michael A. Helmrath (Cincinnati, Ohio); Ethan Mezoff (Cincinnati, Ohio) |
| ABSTRACT | Provided herein are compositions and methods related to use of oligosaccharides, such as 2′-fucosyllactose, for increasing weight gain in a subject. In some aspects the compositions and methods are for use in infants, such as premature infants or infants having intestinal failure. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/569993 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/20 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/30 (20160801) A23L 33/30 (20160801) A23L 33/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2250/284 (20130101) A23V 2250/284 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857178 | Rzigalinski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beverly A. Rzigalinski (Radford, Virginia); Neeraj Singh (Blacksburg, Virginia); Courtney A. Cohen (Frederick, Maryland) |
| ASSIGNEE(S) | EDWARD VIA VIRGINIA COLLEGE OF OSTEOPATHIC MEDICINE (Blacksburg, Virginia) |
| INVENTOR(S) | Beverly A. Rzigalinski (Radford, Virginia); Neeraj Singh (Blacksburg, Virginia); Courtney A. Cohen (Frederick, Maryland) |
| ABSTRACT | Cerium oxide nanoparticles (CeONP) can be used to treat or prevent neurodegenerative diseases, including for example Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, AIDS-related dementia, ALS, progressive supranuclear palsy, and encephalitis, as well as mitochondrial diseases and diseases associated with mitochondrial damage. In particular, CeONP having an average size of about 2 nm to about 100 nm can be administered in an amount sufficient to block production of hydroxyl or superoxide radicals, block free radical production by Aβ(1-42), block Aβ(1-42)-induced neuronal death, block Aβ(1-42)-induced [Ca2+]i dysfunction in neurons, block Aβ(1-42)-induced lipid peroxidation, decrease loss of dopaminergic neurotransmission, or reduce mitochondrial dysfunction in a cell. CeONP can also be effective in treating conditions involving toxic exposures to compounds that induce mitochondrial dysfunction, such as rotenone, cyanide, carbon monoxide, polychlorinated biphenyls (PCBs) and other mitochondrial toxins. |
| FILED | Thursday, October 16, 2008 |
| APPL NO | 12/252905 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 33/24 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857182 | O'Reilly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Richard John O'Reilly (Roxbury, Connecticut); Aisha Nasreen Hasan (Blue Bell, Pennsylvania) |
| ABSTRACT | Provided herein are methods of generating antigen-specific T cells for therapeutic administration to a human patient having or suspected of having a pathogen or cancer, utilizing stem cell-like memory T cells (TSCM cells). Also disclosed are antigen-specific T cells generated by such methods, and methods of treating a human patient using such antigen-specific T cells. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/333651 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 39/245 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) C12N 7/00 (20130101) C12N 2510/00 (20130101) C12N 2710/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857190 | Mani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | Sridhar Mani (Riverdale, New York); Libusha Kelly (Brooklyn, New York); Hao Li (Elmsford, New York) |
| ABSTRACT | Bacterial hyperswarmers are disclosed for treatment, prevention and diagnosis conditions such as intestinal inflammation. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/765513 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) A61K 35/744 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/483 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857197 | Tracey et al. |
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| APPLICANT(S) | The Feinstein Institue for Medical Research (Great Neck, New York) |
| ASSIGNEE(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| INVENTOR(S) | Kevin J. Tracey (Great Neck, New York); Huan Yang (Manhasset, New York); Yousef Al-Abed (Manhasset, New York) |
| ABSTRACT | Methods of treating HMGB1-mediated inflammation by administering a therapeutically effective amount of an MD2-antagonist to a subject in need thereof are described. The novel MD2 antagonist tetrapeptide P5779 is also described. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 15/532226 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/215 (20130101) A61K 31/215 (20130101) A61K 31/7024 (20130101) A61K 31/7024 (20130101) A61K 38/07 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 5/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857199 | Rowe et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Peter S. N. Rowe (Prairie Village, Kansas); Aline Martin (Miami, Florida); Nicolae Valentin David (Miami, Florida); M. Laird Forrest (Lawrence, Kansas); Kenneth Ryan Moulder (Lawrence, Kansas); Shuang Cai (Lawrence, Kansas); Daniel J. Aires (Prairie Village, Kansas) |
| ABSTRACT | A method of promoting hair growth can include: a polypeptide having a sequence that has at least 75% complementarity to or at least 75% identical to SPR4; and topically administering the polypeptide to a subject. This can include putting or causing the polypeptide to be in the skin, such as in any dermal layer. In one aspect, the method can include administering the composition topically so as to administer the polypeptide to the subject. In one aspect, the method can include administering the polypeptide to skin of the subject. In one aspect, the method can include administering the polypeptide to a hair follicle of the subject. In one aspect, the method can include administering the polypeptide to a bald spot of the subject. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/444829 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/14 (20130101) A61K 8/64 (20130101) A61K 9/0014 (20130101) A61K 9/127 (20130101) A61K 9/1075 (20130101) A61K 31/58 (20130101) A61K 31/58 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/6911 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2800/412 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857201 | Yost et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | Ballard Spahr LLP (Salt Lake City, Utah) |
| INVENTOR(S) | Christian Con Yost (Salt Lake City, Utah); Guy A. Zimmerman (Salt Lake City, Utah); Andrew S. Weyrich (Salt Lake City, Utah); Joshua Schiffman (Salt Lake City, Utah) |
| ABSTRACT | Neonatal NET-Inhibitory Factor (nNIF) and nNIF-Related Peptides (NRPs) are provided. Methods for the treatment of and prophylaxis against inflammatory disorders and cancer are also provided. Additionally, methods for the inhibition of metastasis in patients having cancer are provided. The methods can include administering nNIF and/or a NRP to patients having, or at risk of developing, an inflammatory disorder or a cancer. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 16/328697 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/47 (20130101) C07K 14/4703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857209 | Yan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Cong Yan (Carmel, Indiana); Hong Du (Carmel, Indiana) |
| ABSTRACT | Methods of cancer treatment are disclosed. Particularly, disclosed herein are methods of administering LAL and PPARγ ligands for treating various cancer patients to promote anti-cancer immunity (suppress MDSC), use for inhibiting tumor progression, and use for inhibiting tumor metastasis. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 16/077161 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/201 (20130101) A61K 31/201 (20130101) A61K 31/421 (20130101) A61K 31/421 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/5575 (20130101) A61K 31/5575 (20130101) A61K 38/43 (20130101) Original (OR) Class A61K 38/465 (20130101) A61K 38/465 (20130101) A61K 38/1774 (20130101) A61K 38/1774 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) Enzymes C12Y 301/01 (20130101) C12Y 301/01013 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/5743 (20130101) G01N 33/57423 (20130101) G01N 2333/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857210 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Kezhong Zhang (Canton, Michigan); Jiemei Wang (Troy, Michigan) |
| ABSTRACT | Compositions and methods to promote wound healing are described. The compositions and methods up-regulate X-box binding protein 1 (XBP1) and/or inositol-requiring enzyme-1 (IRE-1). In various embodiments, the compositions and methods can be used to promote wound healing in diabetic subjects. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/203628 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/12 (20130101) A61K 9/0014 (20130101) A61K 9/141 (20130101) A61K 38/45 (20130101) Original (OR) Class A61K 38/1709 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10343 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857211 | Wells et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| INVENTOR(S) | Susanne I. Wells (Cincinnati, Ohio); Kenneth D. R. Setchell (Cincinnati, Ohio); Lindsey Romick-Rosendale (Cincinnati, Ohio); Wujuan Zhang (Cincinnati, Ohio); Xueheng Zhao (Cincinnati, Ohio) |
| ABSTRACT | Markers for genomic instability in Fanconi Anemia (FA) and other pathologies for therapeutic and diagnostic uses. In one embodiment, glycosphingolipid metabolism is altered in the FA deficient squamous cell carcinoma (SCC) cells, based on analysis of a metabolomics/lipidomics platform. The data indicated ganglioside metabolism was important in FA patients' susceptibility to SCC progression. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/358620 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) A61K 31/451 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 47/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/57426 (20130101) G01N 2800/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857219 | Hildebrand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University Of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | William H. Hildebrand (Edmond, Oklahoma); Curtis McMurtrey (Oklahoma City, Oklahoma); David Lewinsohn (Portland, Oregon); Deborah Lewinsohn (Portland, Oregon); Melanie Harriff (Portland, Oregon) |
| ABSTRACT | Compositions that include one isolated, class I HLA-E trimolecular complex that includes a peptide ligand unique to M. tuberculosis-infected cells are disclosed. Isolated compositions that include the three components of the trimolecular complex and/or a polynucleotide encoding one or more of the three components are also disclosed. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671322 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/605 (20130101) Peptides C07K 14/35 (20130101) C07K 14/70539 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857220 | McAdow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Molly McAdow (Chicago, Illinois); Andrea Dedent (Chicago, Illinois); Alice Cheng (Chicago, Illinois); Carla Emolo (Chicago, Illinois); Dominique Missiakas (Chicago, Illinois); Olaf Schneewind (Chicago, Illinois) |
| ABSTRACT | The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve coagulase Domains 1-2 and variants thereof. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962115 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) A61K 39/085 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/31 (20130101) C07K 16/1271 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857221 | Granoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Hospital and Research Center at Oakland (Oakland, California) |
| ASSIGNEE(S) | Children's Hospital and Research Center at Oakland (Oakland, California) |
| INVENTOR(S) | Dan M. Granoff (San Francisco, California); Victor Chen-Hsi Hou (Bethlehem, Pennsylvania) |
| ABSTRACT | The present invention generally provides methods and compositions for eliciting an immune response against Neisseria spp. bacteria in a subject, particularly against a Neisseria meningitidis serogroup B strain. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596556 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 39/095 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/22 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857223 | Arts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eric J. Arts (Ontario, Canada); Jamie Mann (Ontario, Canada) |
| ABSTRACT | A method of reducing a latent HIV-specific memory-CD4+ T cell pool in a subject includes administering to the subject at least one HIV-1 protein and a pharmaceutically acceptable carrier, wherein the at least one HIV-1 protein is derived from an allogenic infecting HIV-1 virus, and wherein the HIV-1 protein stimulates latent HIV-specific memory CD4+ T cells to induce latent HIV-1 replication resulting in HIV-specific memory-CD4+ T cell death in the subject. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/252108 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/572 (20130101) A61K 2039/6075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857238 | Mohanty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NANOSCOPE TECHNOLOGIES LLC (Arlington, Texas) |
| ASSIGNEE(S) | Nanoscope Technologies LLC (Bedford, Texas) |
| INVENTOR(S) | Samarendra Kumar Mohanty (Bedford, Texas); Sulagna Bhattacharya (Bedford, Texas) |
| ABSTRACT | Principles of the present disclosure are directed to novel methods and devices for efficient and targeted delivery of impermeable exogenous materials such as small molecules, proteins, antibodies, and genes into cells, both in vitro as well as in vivo, which is of great importance for drug, vaccine and gene delivery for various therapeutic applications. Specifically, the invention provides device and method for targeted nano-enhanced optical delivery of opsins for vision restoration in patients with retinal photodegeneration by conventional intravitreal/sub-retinal injection of gold nano-rods and opsin plasmids followed by scanned/spatially modulated laser beam matching the pathological areas determined by Fundoscopy, OCT or scanning ophthalmoscope. |
| FILED | Monday, February 13, 2017 |
| APPL NO | 16/074041 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) A61B 3/102 (20130101) A61B 3/135 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/00 (20130101) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857243 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Xuewen Du (Waltham, Massachusetts); Jie Zhou (Waltham, Massachusetts); Bing Xu (Newton, Massachusetts) |
| ABSTRACT | The invention relates to an enzymatically responsive product that includes an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. Compositions containing the enzymatically responsive product, and the use thereof for separating distinct types of mammalian cells (e.g., cancer cells from normal cells), for treating a cancerous condition, and imaging cancer cells are also disclosed. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 15/303117 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00345 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 41/0052 (20130101) A61K 45/06 (20130101) A61K 47/52 (20170801) A61K 47/64 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/1866 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/54326 (20130101) G01N 33/57492 (20130101) G01N 2333/916 (20130101) G01N 2440/14 (20130101) G01N 2440/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857244 | Brentnall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through Its Center for Commercialization (Seattle, Washington); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | University of Washington Through Its Center for Communication (Seattle, Washington); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Teresa A. Brentnall (Seattle, Washington); Juergen Karl Willmann (Stanford, California); Sheng Pan (Seattle, Washington) |
| ABSTRACT | The present invention provides reagents and methods for detecting cancer and precancerous lesions in a patient. |
| FILED | Thursday, April 12, 2018 |
| APPL NO | 15/951567 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/221 (20130101) Original (OR) Class A61K 49/223 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857246 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Xing Yang (Baltimore, Maryland); Il Minn (Ellicott City, Maryland); Steven Rowe (Parkville, Maryland); Sangeeta Ray (Ellicott City, Maryland); Ronnie C. Mease (Fairfax, Virginia); Michael Gorin (Towson, Maryland); Mohamad Allaf (Baltimore, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed. |
| FILED | Wednesday, June 01, 2016 |
| APPL NO | 15/578473 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0497 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/12 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857260 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Haitao Cui (Arlington, Virginia); Wei Zhu (Washington, District of Columbia); Lijie Grace Zhang (Washington, District of Columbia) |
| ABSTRACT | A coaxial needle having two or more passageways for forming a biomimetic bioprinted blood vessel tubular construct. The coaxial needle has an external needle passageway and an internal needle passageway separated by an internal barrier, and having a nozzle at an end thereof. A bioink is provided flowable through the external needle passageway and a crosslinking solution is provided flowable through the internal needle passageway. The crosslinking solution contacts the bioink as the crosslinking solution and bioink exit the nozzle thereby forming a tubular blood vessel construct. |
| FILED | Monday, January 08, 2018 |
| APPL NO | 15/864387 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/062 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/18 (20130101) A61L 27/52 (20130101) A61L 27/222 (20130101) A61L 27/507 (20130101) A61L 27/3808 (20130101) A61L 27/3826 (20130101) A61L 2430/22 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/135 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857287 | Damiano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); Beta Bionics, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Beta Bionics, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Edward R. Damiano (Acton, Massachusetts); Rajendranath Selagamsetty (Allston, Massachusetts); Firas H. El-Khatib (Allston, Massachusetts); Bryan D. Knodel (Flagstaff, Arizona); Raymond A. Carr (Lutz, Florida) |
| ABSTRACT | Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament reservoirs, a multi-channel fluid conduit, and an infusion set. The medicament reservoirs and/or collars may be sized and shaped differently such that the medicament reservoirs can only be inserted into the system under selected configurations. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/503269 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/201 (20150501) A61J 1/1406 (20130101) A61J 1/1481 (20150501) A61J 1/2037 (20150501) A61J 1/2065 (20150501) A61J 1/2096 (20130101) A61J 2200/70 (20130101) A61J 2205/10 (20130101) A61J 2205/60 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1408 (20130101) Original (OR) Class A61M 5/1684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857386 | Sheng |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ke Sheng (Los Angeles, California) |
| ABSTRACT | A system and method are provided for generating and delivering a volumetric modulated arc therapy (“VMAT”) plan to a patient. In some aspects, the method includes receiving a representation of a patient comprising information related to target and non-target volumes of interest and generating an objective function based on the representation of the patient. The method also includes performing an iterative optimization process using the objective function to generate a VMAT plan and generating a report according to the VMAT plan. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/941112 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) A61N 5/1039 (20130101) A61N 5/1047 (20130101) Original (OR) Class A61N 5/1065 (20130101) A61N 5/1081 (20130101) A61N 2005/1035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858306 | Guerard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (Paris, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); UNIVERSITE DE NANTES (Nantes, France); UNIVERSITE D'ANGERS (Angers, France); THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (Paris, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); UNIVERSITE DE NANTES (Nantes, France); UNIVERSITE D'ANGERS (Angers, France); THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| INVENTOR(S) | François Guerard (Nantes, France); Jean-François Gestin (Nantes, France); Martin W. Brechbiel (Bethesda, Maryland); Yong-Sok Lee (Bethesda, Maryland) |
| ABSTRACT | The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene. |
| FILED | Thursday, April 09, 2020 |
| APPL NO | 16/844077 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 59/002 (20130101) C07B 59/008 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 17/361 (20130101) C07C 17/361 (20130101) C07C 25/24 (20130101) C07C 25/24 (20130101) C07C 29/10 (20130101) C07C 29/10 (20130101) C07C 29/58 (20130101) C07C 29/58 (20130101) C07C 29/62 (20130101) C07C 29/62 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 33/46 (20130101) C07C 41/18 (20130101) C07C 41/18 (20130101) C07C 43/225 (20130101) C07C 43/225 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/76 (20130101) C07C 201/12 (20130101) Original (OR) Class C07C 201/12 (20130101) C07C 205/11 (20130101) C07C 247/10 (20130101) C07C 247/16 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/50 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858334 | Stahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Shannon Stahl (Madison, Wisconsin); Stephen Tereniak (Madison, Wisconsin) |
| ABSTRACT | An oxidative homocoupling method of synthesizing certain 2,2′-bithiophenes from thiophenes using oxygen as the terminal oxidant is disclosed. In non-limiting examples, the method uses oxygen along with a catalytic system that includes palladium, an assistive ligand, and a non-palladium metal additive to catalyze one of the following reactions: Associated catalytic systems and compositions are also disclosed. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243394 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/04 (20130101) B01J 31/181 (20130101) B01J 31/183 (20130101) B01J 31/184 (20130101) B01J 31/1815 (20130101) B01J 31/1825 (20130101) B01J 31/2239 (20130101) B01J 31/2409 (20130101) B01J 2231/46 (20130101) B01J 2531/16 (20130101) B01J 2531/0205 (20130101) B01J 2531/824 (20130101) B01J 2531/842 (20130101) B01J 2540/10 (20130101) B01J 2540/22 (20130101) B01J 2540/40 (20130101) B01J 2540/225 (20130101) Heterocyclic Compounds C07D 277/32 (20130101) C07D 333/22 (20130101) Original (OR) Class C07D 333/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858338 | Hammock et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bruce Hammock (Davis, California); Sean Kodani (Orangevale, California) |
| ABSTRACT | The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer. |
| FILED | Tuesday, March 14, 2017 |
| APPL NO | 16/084465 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 275/28 (20130101) C07C 275/34 (20130101) C07C 275/36 (20130101) C07C 2601/14 (20170501) Heterocyclic Compounds C07D 211/16 (20130101) C07D 211/46 (20130101) C07D 271/10 (20130101) C07D 401/06 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858360 | Bensen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Merck Sharp and Dohme Corp. (North Wales, Pennsylvania); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | MERCK SHARP and DOHME CORP. (Rahway, New Jersey); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh T. Lam (San Diego, California); Suk J. Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie W. Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (Marlborough, California); Sergio E. Wong (Tracy, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California) |
| ABSTRACT | Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/643760 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858361 | Gangjee |
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| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | A compound of Formula II, or optionally a salt or a hydrate of the compound of Formula II is provided: wherein R1 is selected from the group consisting of a hydrogen, an alkyl group having from one to six carbon atoms, an aryl group, and a heteroaryl group; R2 is selected from the group consisting of an alkyl group having from one to six carbon atoms, a hydrogen, a NRaRb group wherein Ra is either a hydrogen or an alkyl group having from one to six carbon atoms and Rb is either a hydrogen or an alkyl group having from one to six carbon atoms, an aryl group, a heteroaryl group, and a halogen; R is an alkyl group having from one to six carbon atoms; and Ar is selected from the group consisting of an alkyl group having from one to six carbon atoms, a substituted aryl, and a substituted heteroaryl. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 15/929363 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858368 | Canney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); Praeventix, LLC (Exton, Pennsylvania) |
| ASSIGNEE(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania); PRAEVENTIX, LLC (Exton, Pennsylvania) |
| INVENTOR(S) | Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Kevin M. Blattner (Folsom, Pennsylvania); Douglas A. Pippin (Chester Springs, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 16/349811 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 221/00 (20130101) C07D 295/073 (20130101) C07D 309/08 (20130101) C07D 413/10 (20130101) C07D 491/107 (20130101) Original (OR) Class C07D 493/10 (20130101) C07D 513/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858371 | Ghosh |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana) |
| ABSTRACT | Embodiments provide, among other compounds, a family of compounds that can be used as therapeutic anti-cancer agents, methods for using such compounds to treat cancer, and methods of making such compounds. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/335378 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/351 (20130101) A61K 31/357 (20130101) A61K 31/695 (20130101) A61K 31/4025 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 309/14 (20130101) C07D 493/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858381 | Cui et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xinyan Cui (Wexford, Pennsylvania); Noah Snyder (Glenshaw, Pennsylvania); Kasey Catt (Pittsburgh, Pennsylvania); James Eles (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, anti-inflammatory, anti-microbial, and/or cell-adhesion specificity to a surface or material in need thereof, such as a surface of an indwelling medical implant, or a marine surface. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/513064 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04001 (20130101) A61B 17/68 (20130101) A61B 2017/00889 (20130101) A61B 2017/00893 (20130101) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0013 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/24 (20130101) A61F 2/82 (20130101) A61F 2250/0067 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 27/28 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/54 (20130101) A61L 27/54 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/16 (20130101) A61L 31/16 (20130101) A61L 2300/102 (20130101) A61L 2300/102 (20130101) A61L 2300/404 (20130101) A61L 2300/404 (20130101) A61L 2300/404 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0017 (20130101) A61M 2205/0205 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3605 (20130101) A61N 1/3629 (20170801) Heterocyclic Compounds C07D 487/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/02 (20130101) C07F 13/005 (20130101) Original (OR) Class C07F 15/025 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/3432 (20130101) Compositions of Macromolecular Compounds C08L 77/00 (20130101) C08L 77/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858383 | Yu |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Jin-Quan Yu (San Diego, California) |
| ABSTRACT | We report the design of a catalytic, bifunctional template that binds heterocyclic substrate via reversible coordination instead of covalent linkage, allowing remote site-selective C—H olefination of heterocycles. The two metal centers coordinated to this template play different roles; anchoring substrates to the proximity of catalyst and cleaving the remote C—H bonds respectively. Using this strategy, we demonstrate remote site-selective C—H olefination of heterocyclic substrates which do not have functional group handles for covalently attaching templates. For instance the olefination can be an alkenylation of a 3-phenylpyridine with an acrylate alkyl ester selective for the meta position of the phenyl group with respect to the pyridine, or can be an alkenylation of a quinoline with an acrylate alkyl ester selective for the 5-position of the quinoline. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 16/485931 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/04 (20130101) C07D 215/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858396 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Thomas D. Wang (Ann Arbor, Michigan); Bishnu P. Joshi (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure is directed to HER2-specific peptide reagents, methods for detecting pre-cancer (dysplasia), early cancer and/or cancer using the peptide reagents, and methods for targeting pre-cancerous (dysplastic) cells, and/or cancer cells using the peptide reagents. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/780286 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/64 (20170801) A61K 49/0056 (20130101) Peptides C07K 7/00 (20130101) C07K 7/06 (20130101) Original (OR) Class C07K 14/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/82 (20130101) G01N 2333/485 (20130101) G01N 2333/705 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858400 | Kwong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Barney Graham (Rockville, Maryland); Jason McLellan (Austin, Texas); Man Chen (Bethesda, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Yongping Yang (Potomac, District of Columbia) |
| ABSTRACT | Disclosed are immunogens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the immunogens and methods of producing the immunogens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the immunogen to the subject. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/633578 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/03 (20130101) C07K 2319/21 (20130101) C07K 2319/40 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858410 | Polt et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Robin Polt (Tucson, Arizona); Evan M. Jones (Tucson, Arizona); Bobbi Anglin (Tucson, Arizona); Michael L. Heien (Tucson, Arizona); John M. Streicher (Tucson, Arizona) |
| ABSTRACT | Glycosylated peptides with glycosylation at or near the C-terminal domain of the peptide have an enhanced ability to cross the blood brain barrier (BBB) and/or enhanced half-lives. These glycosylated peptides may be used as drugs. For example, a PACAP peptide with a C-terminal glycosylation, e.g., in lieu of the terminal leucine, functions as a PAC1 agonist with enhanced ability to cross the BBB and with enhanced half-life. The peptides can have a pseudoproline residue with glycosylation at or near the C-terminal domain. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752157 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858436 | Bradley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Linda M. Bradley (La Jolla, California); Roberto Tinoco (La Jolla, California) |
| ABSTRACT | The present invention relates to the seminal discovery that P-selectin glycoprotein ligand-1 (PSGL-1) modulates the immune system and immune responses. Specifically, the present invention provides PSGL-1 agonists and antagonists which increase the survival of multifunctional T cells and viral clearance. The present invention further provides methods of treating infectious diseases, cancer and immune and inflammatory diseases and disorders using a PSGL-1 modulator. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 15/324262 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/70596 (20130101) C07K 16/2854 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858444 | Scheinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California) |
| INVENTOR(S) | David Scheinberg (New York, New York); Tao Dao (New York, New York); Cheng Liu (Emeryville, California); Su Yan (Emeryville, California) |
| ABSTRACT | The present invention provides antigen binding proteins that specifically bind to Wilms' tumor protein (WT1), including humanized, chimeric and fully human antibodies against WT1, antibody fragments, chimeric antigen receptors (CARs), fusion proteins, and conjugates thereof. The antigen binding proteins and antibodies bind to HLA-A0201-restricted WT1 peptide. Such antibodies, fragments, fusion proteins and conjugates thereof are useful for the treatment of WT1 associated cancers, including for example, breast cancer, ovarian cancer, prostate cancer, chronic myelocytic leukemia, multiple myeloma, acute lymphoblastic leukemia (ALL), acute myeloid/myelogenous leukemia (AML) and myelodysplastic syndrome (MDS). In more particular embodiments, the anti-WT1/A antibodies may comprise one or more framework region amino acid substitutions designed to improve protein stability, antibody binding and/or expression levels. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/055535 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/32 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 16/2833 (20130101) C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858493 | Parrott |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Matthew Parrott (Chapel Hill, North Carolina) |
| ABSTRACT | A process for chemically recycling polyethylene terephthalate (PET) which utilizes a microwave absorber to optimize glycolytic depolymerization of PET via microwave irradiation. The method of chemically degrading PET to its reactive intermediate, bis(2-hydroxyethyl) terephthalate (BHET), is carried out by: (a) combining PET with ethylene glycol and a catalytic system comprising a catalyst and a microwave absorber to produce a heterogeneous reaction mixture; and then (b) heating by microwave irradiating the reaction mixture to a temperature sufficient to produce a reaction product comprising BHET. The BHET monomer then can be purified and re-polymerized to form new, virgin PET. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/662168 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 67/48 (20130101) C07C 67/54 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/16 (20130101) Original (OR) Class C08J 11/24 (20130101) C08J 11/26 (20130101) C08J 11/28 (20130101) C08J 2367/02 (20130101) C08J 2367/04 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/62 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858627 | Garry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Daniel J. Garry (Eagan, Minnesota); Naoko Koyano-Nakagawa (Shoreview, Minnesota); Mary G. Garry (Eagan, Minnesota); Bhairab Singh (Falcon Heights, Minnesota) |
| ABSTRACT | Disclosed is a method to differentiate stern, progenitor or precursor cells comprising contacting said stem, progenitor or precursor cells with miR-130a, or an RNA having at least 95% identity thereto, so as to yield cells of endothelial lineage. Further disclosed are compositions comprising the endothelial lineage cells obtained and methods of using the compositions for treating diseases including cardiovascular diseases. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/748772 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 17/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0606 (20130101) C12N 5/0647 (20130101) Original (OR) Class C12N 5/0692 (20130101) C12N 5/0696 (20130101) C12N 2310/141 (20130101) C12N 2501/65 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858632 | Hewitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Curtis Hewitt (Austin, Texas); Richard Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | This invention relates to modified parvovirus inverted terminal repeats (ITRs) that do not functionally interact with wild-type large Rep proteins, synthetic Rep proteins that functionally interact with the modified ITRs, and methods of using the same for delivery of nucleic acids to a cell or a subject. The modifications provide a novel Rep-ITR interaction that limits vector mobilization, increasing the safety of viral vectors. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/271163 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14162 (20130101) C12N 2750/14322 (20130101) C12N 2750/14352 (20130101) C12N 2820/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858636 | Lambowitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Alan M. Lambowitz (Austin, Texas); Sabine Mohr (Austin, Texas); Georg Mohr (Austin, Texas); Eman Ghanem (Raleigh, North Carolina) |
| ABSTRACT | Stabilized reverse transcriptase fusion proteins including a thermostable reverse transcriptase connected to a stabilizer protein are described. Attaching the stabilizer protein to the thermostable reverse transcriptase stabilizes the fusion protein and can aid in its purification, provide increased solubility, allow for longer storage, or allow the fusion protein to be used under more rigorous conditions such as higher temperature. The stabilized reverse transcriptase fusion protein can also include a linker between the stabilizer protein and the thermostable reverse transcriptase. The stabilized reverse transcriptase fusion proteins are suitable for use in nucleic acid amplification methods such as the reverse transcription polymerase chain reaction and other applications involving cDNA synthesis. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/051549 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858650 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeannie T. Lee (Cambridge, Massachusetts); Kavitha Sarma (Waltham, Massachusetts) |
| ABSTRACT | Methods and compositions for modulation of the activity of alpha thalassemia/mental retardation syndrome X-linked (ATRX), e.g., modulation of DNA-ATRX or RNA-ATRX interactions, and methods for identifying and using compounds that modulate DNA-ATRX or RNA-ATRX interactions, as well as the compounds themselves. |
| FILED | Friday, October 30, 2015 |
| APPL NO | 15/522171 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 39/395 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 15/1093 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/15 (20130101) C12N 2310/113 (20130101) C12N 2310/531 (20130101) C12N 2310/1241 (20130101) C12N 2320/11 (20130101) C12N 2330/31 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/08 (20130101) C40B 50/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/914 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858654 | Leof et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Edward B. Leof (Rochester, Minnesota); Mark C. Wilkes (Plainview, Minnesota); Claire E. Repellin (Alameda, California); Jeong-Han Kang (Rochester, Minnesota); Xueqian Yin (Rochester, Minnesota); Mahefatiana Andrianifahanana (Rochester, Minnesota) |
| ABSTRACT | This document provides polypeptide inhibitors of Smad3 polypeptide activities. For example, methods and materials for using polypeptides (e.g., polypeptides designed to include both a cell penetrating amino acid sequence and an amino acid segment of a SH3 domain of a SNX9 polypeptide) to inhibit one or more Smad3 polypeptide activities are provided. This document also provides methods and materials for using RNA interference to treat a disease (e.g., a fibrotic disease) in a mammal (e.g., a human). |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/184768 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) A61K 38/10 (20130101) A61K 38/16 (20130101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) C07K 14/4702 (20130101) C07K 14/4703 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858681 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California); Stephanie Galanie (Palo Alto, California) |
| ABSTRACT | Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes involved in synthetic pathways from starting compounds to BIAs of the host cell. Also provided are methods of producing the BIAs of interest by culturing the host cells under culture conditions that promote expression of enzymes encoded by the heterologous coding sequences of the host cells. Aspects of the invention further include compositions, e.g., host cells, starting compounds and kits, etc., that find use in methods of the invention. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/978005 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) C12N 9/1007 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/18 (20130101) C12P 17/182 (20130101) Original (OR) Class Enzymes C12Y 121/03003 (20130101) C12Y 201/0114 (20130101) C12Y 201/01116 (20130101) C12Y 201/01128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858692 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kun Zhang (Brighton, Massachusetts); Joseph Chou (Jamaica Plain, Massachusetts) |
| ABSTRACT | Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945192 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858693 | Sardar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH and TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH and TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Rajesh Sardar (Indianapolis, Indiana); Murray Korc (Indianapolis, Indiana); Gayatri K. Joshi (Carmel, Indiana) |
| ABSTRACT | Biosensors and methods for localized surface plasmon resonance biosensing are disclosed. The biosensor can include a substrate having a substrate surface to which a plurality of localized surface plasmon resonance (LSPR) antennae are affixed. The LSPR antennae can be affixed via an affixation surface of the LSPR antenna. The LSPR antennae can have a functional surface opposite the affixation surface. Each functional surface can be functionalized by a plurality of single-stranded DNA. |
| FILED | Tuesday, October 06, 2015 |
| APPL NO | 15/517383 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 2525/207 (20130101) C12Q 2565/628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858700 | Gundlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Andrew Laszlo (Seattle, Washington) |
| ABSTRACT | The present disclosure provides methods and reagents for improving nanopore-based analyses of polymers. Specifically, the disclosure provides a method of analyzing a polymer that includes a polymer analyte that contains an end domain that has at least one charged moiety. The disclosure also provides a method of increasing the interaction rate between a polymer analyte and a nanopore, wherein the polymer analyte contains an end domain that has at least one charged moiety. The disclosure also provide compositions for use with the described methods, including adapter compositions that contain charged moieties, such as phosphate or sulfate groups, and that are configured to being linked to an polymer analyte domain. |
| FILED | Friday, August 02, 2013 |
| APPL NO | 14/419217 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2523/31 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858705 | Pollak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Martin Pollak (Brookline, Massachusetts); Elizabeth J. Brown (Dallas, Texas); Johannes Schlondorff (Chestnut Hill, Massachusetts) |
| ABSTRACT | This document features method related to variants in the Inverted Formin 2 (INF2) gene that are associated with susceptibility to focal segmental glomerulosclerosis (FSGS). For example, methods of using such variants for risk assessment and for diagnosing and optimizing treatment of FSGS are provided. |
| FILED | Wednesday, October 19, 2016 |
| APPL NO | 15/297804 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6811 (20130101) C12Q 1/6813 (20130101) C12Q 1/6816 (20130101) C12Q 1/6827 (20130101) C12Q 1/6876 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858707 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Jewish Health (Denver, Colorado) |
| ASSIGNEE(S) | NATIONAL JEWISH HEALTH (Denver, Colorado) |
| INVENTOR(S) | David A. Schwartz (Aurora, Colorado); Max Seibold (Denver, Colorado) |
| ABSTRACT | The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 15/802281 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/4725 (20130101) G01N 2800/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858711 | Zhu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Tuofu Zhu (Seattle, Washington) |
| ABSTRACT | Primers and probes for detecting an RNA virus, including HIV, HIV-1 subtypes of the M and O groups, and HCV, in a sample. The primers and probes can be used for monitoring the efficacy of anti-retroviral treatment in a subject infected with HIV and/or HCV, and for detecting acute HIV-1 infection, and/or acute HCV infection, in a subject. Included are inner, middle and outer primers that can be used in PCR, including triple nested PCR in a single tube. The methods are highly sensitive and specific, allowing for detection of as few as 4 copies of virus in a sample. |
| FILED | Tuesday, February 23, 2016 |
| APPL NO | 15/553083 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 1/707 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859527 | Swain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Greg M. Swain (Owosso, Michigan); Serban F. Peteu (East Lansing, Michigan); Borys W. Hrinczenko (East Lansing, Michigan) |
| ABSTRACT | The disclosure relates to electrodes and related sensor apparatus for the detection of nitric oxide (NO) and/or peroxynitrite (PON). The electrodes and sensors incorporate electrically conducting boron-doped diamond (BDD) to provide a selective and quantitative detection platform. The sensing electrode for detection of NO includes metallic nanoparticles for oxidation of NO as well as anionic polyelectrolyte layer over the electrically conducting BDD layer. The sensing electrode for detection of PON includes an electrically conductive polymeric layer including a metal-complexed porphyrin for redox reaction with PON over the electrically conducting BDD layer. A corresponding sensor apparatus includes one or two electrochemical cells with associated electrolytes, separate working electrodes for the separate, selective detection of NO or PON, and associated reference electrode(s) and counter electrode(s). Use of the related sensor with various electrochemical techniques to detect NO and/or PON in exhaled breath can be used for detection and/or diagnosis of lung-related conditions. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885024 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/097 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/413 (20130101) G01N 27/4045 (20130101) G01N 27/4072 (20130101) G01N 27/4074 (20130101) G01N 27/4075 (20130101) Original (OR) Class G01N 27/4076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859569 | Blanchard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Scott Blanchard (New York, New York); Harel Weinstein (New York, New York); Jonathan Javitch (New Rochelle, New York) |
| ABSTRACT | This disclosure is directed to methods of conducting dynamic single-molecule fluorescence studies such as smFRET on a membrane protein which permits observation and quantification of conformational dynamics of a membrane protein. Also disclosed herein are mutant membrane proteins in which one or more mutations have been introduced for affixing a fluorophore, as well as reagents and kits containing such mutant membrane proteins for conducting dynamic single-molecule fluorescence studies. The methods and compositions disclosed herein can be used in screening for compounds that enhance or reduce the activity of a membrane protein, useful for treating diseases associated with the malfunction of the membrane protein or alterations in membrane protein conformation. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/355819 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Peptides C07K 14/001 (20130101) C07K 14/195 (20130101) C07K 14/245 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/542 (20130101) Original (OR) Class G01N 33/582 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859582 | Sigurdsson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Einar M. Sigurdsson (Scarsdale, New York) |
| ABSTRACT | The present invention relates to antibody-based probes (including single domain antibody fragment, scFv molecules, antibodies, antibody fragments, diabodies, and the epitope-binding domains thereof) that are capable of immunospecifically and selectively binding to a phosphoserine-containing epitope of Tau, such as, for example, Tau-phospho-serine 396/404 peptide. Such imaging ligands are useful to detect pathological Tau protein conformer if present in a biological sample, especially in conjunction with the diagnosis of Alzheimer's disease or other tauopathy, and thus provide a diagnostic for Alzheimer's disease and other Tau pathologies. The scFv molecules of the present invention have utility as diagnostic markers for, Alzheimer's disease and related tauopathies and as pharmaceutical compositions for the treatment of such conditions. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/151555 |
| ART UNIT | 1699 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 49/0058 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/30 (20130101) C07K 2317/34 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2440/14 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859585 | Cravatt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Benjamin F. Cravatt (La Jolla, California); Micah J. Niphakis (San Diego, California); Kenneth Lum (San Diego, California); Bruno Correia (Blemblens, Switzerland); Armand Cognetta (San Diego, California); Jonathan Hulce (Libertyville, Illinois) |
| ABSTRACT | Disclosed herein are methods, compositions, probes, assays and kits for identifying a lipid binding protein as a drug binding target. Also disclosed herein are methods, compositions, and probes for mapping a ligand binding site on a lipid binding protein, identification of lipid binding proteins, generating drug-lipid binding protein profiles, high throughput drug screening, and identification of drugs as potential lipid binding protein ligands. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235096 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/6842 (20130101) G01N 2500/04 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859654 | Gulani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Vikas Gulani (Shaker Heights, Ohio); Satyam Ghodasara (Cleveland, Ohio); Katherine Wright (Macedonia, Ohio); Nicole Seiberlich (Shaker Heights, Ohio); Mark A. Griswold (Shaker Heights, Ohio) |
| ABSTRACT | A method for determining quantitative parameters for dynamic contrast-enhanced MR data includes acquiring a set of contrast-enhanced MR data for a region of interest using a T1-weighted pulse sequence, generating at least one contrast concentration curve based on the set of contrast-enhanced MR data, accessing a comprehensive dictionary of contrast concentration curves and generating a grouped dictionary that has a plurality of groups based on the comprehensive dictionary. Each group includes a plurality of correlated contrast concentration curves and a group representative signal for the group. The method also includes comparing a contrast concentration curve with the group representative signal of each group to select a group, comparing the contrast concentration curve to the plurality of correlated contrast concentration curves in the selected group to identify a set of quantitative parameters for the concentration curve and generating a report including the set of quantitative parameter. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/351404 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/281 (20130101) G01R 33/443 (20130101) G01R 33/5601 (20130101) G01R 33/5602 (20130101) Original (OR) Class G01R 33/56308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859658 | Edelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHSHORE UNIVERSITY HEALTHSYSTEM (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHSHORE UNIVERSITY HEALTHSYSTEM (Evanston, Illinois) |
| INVENTOR(S) | Robert R. Edelman (Highland Park, Illinois); Ioannis Koktzoglou (Des Plaines, Illinois) |
| ABSTRACT | A system and method for controlling a magnetic resonance imaging (MRI) system to create magnetic resonance (MR) cine angiograms of a subject. The method includes controlling the MRI system to acquire MR data from the subject by performing at least one cine acquisition pulse sequence having a plurality of acquisition RF pulse modules applied at constant intervals throughout a cardiac cycle, and at least one labeling pulse sequence including a first and a second α/2 module and a labeling RF pulse module for labeling a region of inflowing arterial flow through a vessel of interest. The method further includes reconstructing the MR data to form a series of cine frames that form a cine angiogram, subtracting at least one cine frame from other cine frames reconstructed from the MR data, and displaying the MR cine angiogram of the vessel of interest. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/395835 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5608 (20130101) G01R 33/5613 (20130101) G01R 33/5635 (20130101) Original (OR) Class G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861152 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Cleveland, Ohio); Prateek Prasanna (Cleveland, Ohio) |
| ABSTRACT | Embodiments access a radiological image of tissue having a tumoral volume and a peritumoral volume; define a vasculature associated with the tumoral volume; generate a Cartesian two-dimensional (2D) vessel network representation; compute a first set of localized Hough transforms based on the Cartesian 2D vessel network representation; generate a first aggregated set of peak orientations based on the first set of Hough transforms; generate a spherical 2D vessel network representation; compute a second set of localized Hough transforms based on the spherical 2D vessel network representation; generate a second aggregated set of peak orientations based on the second set of Hough transforms; generate a vascular network organization descriptor based on the aggregated peak orientations; compute a probability that the tissue is a member of a positive class based on the vascular network organization descriptor; classify the ROI based on the probability; and display the classification. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/354504 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7253 (20130101) A61B 5/7267 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/628 (20130101) G06K 9/4633 (20130101) G06K 9/6228 (20130101) G06K 9/6277 (20130101) G06K 9/6286 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/62 (20170101) G06T 7/70 (20170101) G06T 7/187 (20170101) G06T 15/08 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20044 (20130101) G06T 2207/20061 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20116 (20130101) G06T 2207/20152 (20130101) G06T 2207/30064 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861156 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Andrew Janowczyk (East Meadow, New York) |
| ABSTRACT | Embodiments include accessing a set of digital pathology (DP) images having an imaging parameter; applying a low-computational cost histology quality control (HistoQC) pipeline to the DP images, where the low-computational cost HistoQC pipeline computes a first set of image metrics associated with a DP image, and assigns the DP image to a first or a second, different cohort based on the imaging parameter and the first set of image metrics; applying a first, higher-computational-cost HistoQC pipeline to a member of the first cohort; applying a second, different higher-computation-cost HistoQC pipeline to a member of the second cohort; where the first or second, higher-computational-cost HistoQC pipeline determines an artifact-free region of the member of the first or second cohort, respectively, and classifies the member of the first or second cohort, respectively, as suitable or unsuitable for downstream computation or diagnostic analysis based, at least in part, on the artifact free region. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 16/246650 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 7/0014 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862168 | Wessells et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Natron Energy, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Natron Energy, Inc. (Santa Clara, California) |
| INVENTOR(S) | Colin Deane Wessells (Palo Alto, California); Shahrokh Motallebi (Los Gatos, California) |
| ABSTRACT | A system and method for stabilizing electrodes against dissolution and/or hydrolysis including use of cosolvents in liquid electrolyte batteries for three purposes: the extension of the calendar and cycle life time of electrodes that are partially soluble in liquid electrolytes, the purpose of limiting the rate of electrolysis of water into hydrogen and oxygen as a side reaction during battery operation, and for the purpose of cost reduction. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/215339 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/36 (20130101) H01M 4/58 (20130101) H01M 4/60 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/628 (20130101) H01M 4/9008 (20130101) H01M 8/188 (20130101) H01M 10/08 (20130101) H01M 10/36 (20130101) H01M 10/44 (20130101) H01M 10/056 (20130101) H01M 10/345 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2220/10 (20130101) H01M 2220/20 (20130101) H01M 2250/10 (20130101) H01M 2250/20 (20130101) H01M 2300/0002 (20130101) H01M 2300/002 (20130101) H01M 2300/004 (20130101) H01M 2300/0025 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101) H01M 2300/0091 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 90/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48347 | Mugler, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | John P. Mugler, III (Charlottesville, Virginia); James R. Brookeman (Charlottesville, Virginia) |
| ABSTRACT | A magnetic resonance imaging “MRI” method and apparatus for lengthening the usable echo-train duration and reducing the power deposition for imaging is provided. The method explicitly considers the t1 and t2 relaxation times for the tissues of interest, and permits the desired image contrast to be incorporated into the tissue signal evolutions corresponding to the long echo train. The method provides a means to shorten image acquisition times and/or increase spatial resolution for widely-used spin-echo train magnetic resonance techniques, and enables high-field imaging within the safety guidelines established by the Food and Drug Administration for power deposition in human MRI. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/195079 |
| ART UNIT | 3992 — Central Reexamination Unit (Electrical) |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/586 (20130101) G01R 33/5615 (20130101) Original (OR) Class G01R 33/5617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10856740 | Arbabian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Mohammad Amin Arbabian (San Francisco, California); Hao Nan (Stanford, California) |
| ABSTRACT | A thermoacoustic imaging device is provided having a transmitter configured to provide an electromagnetic transmit signal (e.g. a continuous sinusoidal signal) to an object being imaged. The transmit signal is a modulated continuous-wave signal based on a carrier frequency signal fc modulated at a modulation frequency at or near fm. The detector is further configured to receive an acoustic signal from the object being imaged, and is responsive to acoustic frequencies at or near 2fm. A non-linear thermoacoustic effect in the object being imaged generates the acoustic signal from the object being imaged. Spectroscopic maps could be generated and imaged object could be analyzed. The device enhances signal-to-noise ratio of the reconstructed image and reduces the requirement of peak power in thermoacoustic imaging systems. In addition, the generated pressure of the imaged object is separated from microwave leakage and feedthrough in frequency through the nonlinear thermoacoustic effect. |
| FILED | Tuesday, March 03, 2015 |
| APPL NO | 14/636412 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0093 (20130101) Original (OR) Class A61B 8/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856752 | Banet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Matt Banet (Kihei, Hawaii); Isaac Henry (La Mesa, California); Donald Bernstein (Rancho Santa Fe, California) |
| ASSIGNEE(S) | SOTERA WIRELESS, INC. (San Diego, California) |
| INVENTOR(S) | Matt Banet (Kihei, Hawaii); Isaac Henry (La Mesa, California); Donald Bernstein (Rancho Santa Fe, California) |
| ABSTRACT | The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. |
| FILED | Tuesday, December 27, 2011 |
| APPL NO | 13/338235 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0008 (20130101) A61B 5/021 (20130101) A61B 5/0022 (20130101) A61B 5/029 (20130101) A61B 5/0205 (20130101) A61B 5/0245 (20130101) A61B 5/0295 (20130101) Original (OR) Class A61B 5/0535 (20130101) A61B 5/681 (20130101) A61B 5/725 (20130101) A61B 5/746 (20130101) A61B 5/0816 (20130101) A61B 5/1116 (20130101) A61B 5/02028 (20130101) A61B 5/02427 (20130101) A61B 5/6823 (20130101) A61B 5/6824 (20130101) A61B 5/6826 (20130101) A61B 5/6833 (20130101) A61B 5/7239 (20130101) A61B 5/14542 (20130101) A61B 5/14551 (20130101) A61B 2562/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856765 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LR Technologies, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | LR Technologies, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Eugene Yu-Jiun Ren (San Marcos, California); Yexian Qin (Tuscon, Arizona); Chiehping Lai (Rockville, Maryland) |
| ABSTRACT | The present disclosure includes an electromagnetic field detection and monitoring system. The system includes passive detection, active detection, and signal processing capabilities. At least one embodiment includes a body worn system with sensing, processing, communications, and data storage capabilities. The system provides wearable antennas to transfer the EMF energy in its electrical or magnetic forms into the sensor efficiently. A specially designed processing algorithm can process the collected data and generated the results for medical professionals to read and make decisions. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277968 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) Original (OR) Class A61B 5/0408 (20130101) A61B 5/0464 (20130101) A61B 5/0476 (20130101) A61B 5/721 (20130101) A61B 5/6804 (20130101) A61B 5/7264 (20130101) Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 1/273 (20130101) H01Q 1/2291 (20130101) H01Q 5/335 (20150115) H01Q 21/28 (20130101) Selecting H04Q 9/00 (20130101) H04Q 9/02 (20130101) H04Q 2209/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856815 | Pereira et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| INVENTOR(S) | Francisco Pereira (Jersey City, New Jersey); Bin Lou (West Windsor, New Jersey); Angeliki Lazaridou (Artemida, Greece) |
| ABSTRACT | By way of introduction, the present embodiments described below include apparatuses and methods for generating natural language representations of mental content from functional brain images. Given functional imaging data acquired while a subject reads a text passage, a reconstruction of the text passage is produced. Linguistic semantic vector representations are assigned (1301) to words, phrases or sentences to be used as training stimuli. Basis learning is performed (1305), using brain imaging data acquired (1303) when a subject is exposed to the training stimuli and the corresponding semantic vectors for training stimuli, to learn an image basis directly. Semantic vector decoding (1309) is performed with functional brain imaging data for test stimuli and using the image basis to generate a semantic vector representing the test imaging stimuli. Text generation (1311) is then performed using the decoded semantic vector representing the test imaging stimuli. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/752276 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) A61B 5/04842 (20130101) A61B 5/7267 (20130101) Original (OR) Class Electric Digital Data Processing G06F 40/30 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857008 | Haque et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Impulse Technology LLC (State College, Pennsylvania) |
| ASSIGNEE(S) | Impulse Technology LLC (State College, Pennsylvania) |
| INVENTOR(S) | Md Amanul Haque (State College, Pennsylvania); Vamsidhar Reddy Rajula (State College, Pennsylvania); Mst (Kamrun) Kamrunnahar (State College, Pennsylvania) |
| ABSTRACT | A self-adjusting adapter for a prosthetic leg having a foot and a leg socket has a low stiffness spring having a central opening, a high stiffness spring that has a central opening and is adjacent the low stiffness spring, a shaft or a bolt passing through the central opening in the low stiffness spring and the central opening in the high stiffness spring and a spring stiffener configured and positioned to restrain movement of the high stiffness spring relative to the low stiffness spring in a direction parallel to the low-stiffness spring. A connector for attaching the adapter to a leg socket is connected to the bolt or shaft and is capable of pivoting about an axis through the bolt or shaft. The adapter can be used an add-on component for existing prosthetic legs, or it can be integrated with foot design for the ankle-foot product category. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/536935 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 2002/503 (20130101) A61F 2002/5078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857161 | McCall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Kanneboyina Nagaraju (Columbia, Maryland) |
| ABSTRACT | Provided herein is a pharmaceutical composition comprising a compound having the structural formula wherein the compound is present in an amount effective to treat or reduce the symptoms of muscular dystrophy. The therapeutically effective amount may be between 10 mg to 200 mg, or may be between 0.01 mg/kg to 10.0 mg/kg. Also provided are methods of treating or reducing the symptoms of muscular dystrophy, comprising the administration, to a patient in need thereof, of a therapeutically effective of the above compound. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/226061 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/573 (20130101) Original (OR) Class A61K 31/575 (20130101) Steroids C07J 5/0038 (20130101) C07J 5/0053 (20130101) C07J 5/0076 (20130101) Technologies for Adaptation to Climate Change Y02A 50/479 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/824 (20130101) Y10S 514/825 (20130101) Y10S 514/826 (20130101) Y10S 514/903 (20130101) Y10S 514/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857427 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel King (Watertown, Massachusetts); Isaac Ehrenberg (Brookline, Massachusetts); Alexander Sawyer (Seekonk, Massachusetts); Graham Arrick (Cambridge, Massachusetts); Juliette E. Mahaffey (Boston, Massachusetts); William McFarland (Waltham, Massachusetts); David Carter (Concord, Massachusetts) |
| ABSTRACT | A hard-point fixture placement system places a fixture that is pre-loaded with a curable adhesive by mechanically extruding the adhesive between the fixture and a target surface to which the fixture is to be attached. The placement system includes an irradiating device to cure the adhesive. The hard-point fixture stores the adhesive in a reservoir that is protected from the curing radiation. Once the curing process is complete, the fixture is released from the placement system leaving the fixture affixed to the target surface. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 15/986144 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 1/00 (20130101) A63B 29/08 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 2035/0211 (20130101) B29C 2035/0822 (20130101) B29C 2035/0827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857773 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kevin Thomas Turner (Wayne, Pennsylvania); David Scott Grierson (Madison, Wisconsin) |
| ABSTRACT | Transfer of nanoscale elements from a substrate on which they were manufactured or transferred to a flexible sheet may be performed by local and progressive deformation of the flexible sheet over the surface of the substrate to attach and lift the nanoscale elements from the substrate with controlled inter-element registration. |
| FILED | Wednesday, July 08, 2015 |
| APPL NO | 14/794232 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/026 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/00 (20130101) B29K 2079/08 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/755 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/025 (20130101) Original (OR) Class B32B 37/0053 (20130101) B32B 38/06 (20130101) B32B 38/10 (20130101) B32B 38/1825 (20130101) B32B 38/1875 (20130101) B32B 41/00 (20130101) B32B 2367/00 (20130101) B32B 2379/08 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/002 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1195 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858239 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annadale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293455 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858240 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annadale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293457 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858253 | Snure et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Michael R. Snure (Dayton, Ohio); David Weyburne (Maynard, Massachusetts) |
| ABSTRACT | A low pressure process for producing thin film crystalline black phosphorus on a substrate and a black phosphorus thin film made by the process. The process includes flowing a phosphorus-containing gas into a deposition chamber and depositing phosphorus from the phosphorus-containing gas onto the substrate in the chamber. The substrate is selected from (i) a gold substrate, a gold-tin alloy substrate, a silver substrate and a copper substrate and (ii) a substrate comprising a thin film of metal selected from gold, tin, silver, copper and alloys of the foregoing metals. The substrate and phosphorus are heated to a temperature ranging from about 350° to less than about 500° C. to form a phosphorus intermediate composition. The substrate and intermediate composition are heated to a temperature of greater than 500° C. to less than about 1000° C. convert the metal phosphorus intermediate composition to the black phosphorus thin film. |
| FILED | Wednesday, December 26, 2018 |
| APPL NO | 16/232425 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/02 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858256 | Gui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California); Jason K. Streit (Gaithersburg, Maryland); Angela R. Hight Walker (Gaithersburg, Maryland); Ming Zheng (Gaithersburg, Maryland) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California); Government of the United States of America, as Represented by the Secretary of Commerce, National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | Hui Gui (Los Angeles, California); Jason K. Streit (Gaithersburg, Maryland); Angela R. Hight Walker (Gaithersburg, Maryland); Chongwu Zhou (San Marino, California); Ming Zheng (Rockville, Maryland) |
| ABSTRACT | A method of separating and extracting carbon nanotubes, the method includes introducing the carbon nanotubes into a two-phase system that includes a first component and a second component, the first component being different from the second component. The method includes introducing a chemical agent into the two-phase system, mixing the chemical agent and the carbon nanotubes in the two-phase system, removing the first component to extract a first portion of the carbon nanotubes contained in the first component after the mixing, replenishing the two-phase system with fresh first component, and extracting a second portion of the carbon nanotubes contained in the fresh first component. A bandgap of the carbon nanotubes in the first portion is different from the bandgap of the carbon nanotubes in the second portion. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/545659 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/17 (20170801) C01B 32/172 (20170801) Original (OR) Class C01B 2202/02 (20130101) C01B 2202/22 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858297 | Krawietz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Krawietz (Shalimar, Florida); Victor Bellitto (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Krawietz (Shalimar, Florida); Victor Bellitto (Alexandria, Virginia) |
| ABSTRACT | An explosive composition, an insensitive munition with a metal eutectic binder, and a method include using a metal eutectic binder with metal coated explosive particles. The metal eutectic binder concept represents novel melt-cast solid mixtures having explosives such as RDX (cyclonite) or HMX (octogen) distributed in an alloy including, for example, eutectic bismuth (Bi)/tin (Sn). Eutectic alloys are particularly considered to provide a melting point of the mixture below the exothermic point of the explosive so that vented munitions disarm by melting without exploding in the event of fire or other elevated heating. Particularly novel is the pre-coating of crystals of explosive (RDX/HMX) with a metal to promote wetting and bonding during melt fabrication of the final mixture. Copper, aluminum, and other metals are considered for use as coating. |
| FILED | Wednesday, July 09, 2014 |
| APPL NO | 14/120909 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858410 | Polt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Robin Polt (Tucson, Arizona); Evan M. Jones (Tucson, Arizona); Bobbi Anglin (Tucson, Arizona); Michael L. Heien (Tucson, Arizona); John M. Streicher (Tucson, Arizona) |
| ABSTRACT | Glycosylated peptides with glycosylation at or near the C-terminal domain of the peptide have an enhanced ability to cross the blood brain barrier (BBB) and/or enhanced half-lives. These glycosylated peptides may be used as drugs. For example, a PACAP peptide with a C-terminal glycosylation, e.g., in lieu of the terminal leucine, functions as a PAC1 agonist with enhanced ability to cross the BBB and with enhanced half-life. The peptides can have a pseudoproline residue with glycosylation at or near the C-terminal domain. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752157 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858652 | Ellington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Andrew Ellington (Austin, Texas); Jared Ellefson (Austin, Texas); Jimmy Gollihar (Austin, Texas) |
| ABSTRACT | Embodiments of the disclosure concern methods and compositions related to generation and/or use of proofreading reverse transcriptases, including those that are thermophilic or hyperthermophilic. The disclosure encompasses specific recombinant polymerases and their use. In some embodiments, the polymerases are utilized for RNA sequencing in the absence of generation of a cDNA intermediate. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/407163 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) C12N 15/1096 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858855 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Justin M Roberts (Florence, Mississippi); John M Hoemann (Vicksburg, Mississippi); Craig R Ackerman (Gainesville, Virginia) |
| ABSTRACT | The modular anti-ballistic shelter system includes two end units and, optionally, additional middle units for a wider structure. End and middle units may also stack atop each other for multi-story structures. Each unit is configured to comply with both ISO standards for size and weight, and with the U.S. Department of State Certification Standard for Forced Entry and Ballistic Resistance of Structural Systems. Each exterior wall of each end unit and each middle unit is reinforced with wall studs that penetrate the unit's structural framework of beams and frames. Even though these wall studs are welded into place, penetration of the wall studs into the beams and frames ensures acceptable blast, ballistic, and forced entry resistance even if the welds are flawed. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/355459 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/1912 (20130101) E04B 1/2403 (20130101) E04B 2/58 (20130101) E04B 5/10 (20130101) E04B 7/022 (20130101) E04B 2001/199 (20130101) E04B 2001/1972 (20130101) E04B 2001/2427 (20130101) E04B 2001/2448 (20130101) E04B 2001/2463 (20130101) E04B 2001/2466 (20130101) E04B 2001/2481 (20130101) E04B 2001/2484 (20130101) E04B 2103/06 (20130101) Structural Elements; Building Materials E04C 3/06 (20130101) E04C 3/32 (20130101) E04C 2003/0465 (20130101) E04C 2003/0473 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/10 (20130101) Original (OR) Class E04H 2001/1283 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 1/02 (20130101) E06B 1/56 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/24 (20130101) F41H 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859356 | Dindl |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Frank J. Dindl (Newton, New Jersey) |
| ABSTRACT | A liquid or powder filled cartridge is used to cool and lubricate the bore of gun barrels to eliminate cook off and improve barrel life. A primer is used to rupture the nose of the cartridge and propel the cooling material into the bore. The coolant absorbs heat from the bore of the barrel and is ejected from the muzzle of the weapon. The liquid or powder may include lubricants, preservatives, antifreeze, coolants, cleaners, or mixtures thereof, or other materials to enhance barrel performance. The liquid or powder filled cartridge is particularly well suited to externally powered weapons. Ammunition may be fed into the weapon using a mix of conventional cartridges and coolant filled cartridges. Internally cooling the barrel may be used to reduce or eliminate cook off and increase barrel life. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784789 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 9/29 (20130101) F41A 9/50 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/24 (20130101) F42B 5/145 (20130101) F42B 14/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859358 | Burke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gregory Burke (Haverhill, New Hampshire); John Hirlinger (Hackettstown, New Jersey); Thomas DeVoe (Randolph, New Jersey); Christopher Csernica (Port Murray, New Jersey); Viral Panchal (Parlin, New Jersey); Mohamed Elalem (Carteret, New Jersey) |
| ABSTRACT | An ignition system for energetics including artillery charges includes a radio frequency transmitter and a radio frequency igniter. The radio frequency igniter receives and converts radio frequency energy into heat or electrical energy for the purpose of igniting energetics, such as propellants or pyrotechnics. The radio frequency igniter may be applied to the exterior of the energetic container or may be integral to the container. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/136493 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 19/63 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/10 (20130101) F42B 5/08 (20130101) F42B 5/38 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/001 (20130101) F42C 13/04 (20130101) F42C 13/045 (20130101) Original (OR) Class F42C 13/047 (20130101) F42C 19/0823 (20130101) F42C 19/0834 (20130101) Blasting F42D 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859359 | Shaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Michael J. Shaw (Epsom, New Hampshire); Benjamin K. Campbell (Nashua, New Hampshire); Ryan Dippel (Arlington, Massachusetts); Matthew M. Hall (Nashua, New Hampshire); Andrew Kaye (Alamo, California); John A. Mitchell (Amherst, New Hampshire); William R. Samuels (Wilton, New Hampshire); Timothy W. Spence (Hollis, New Hampshire); Heather A. Wickman (Hollis, New Hampshire) |
| ABSTRACT | The system and method for forming an ignition sequencer comprising two inseparable portions (a body and an armature) where an armature is articulable with respect to a body to allow for the existence of no less than two distinct stages of the ignition sequence through the articulating motion of the additively-manufactured armature. The ignition sequencer assembly architecture allows for installation of an internal energetic compound while all components are assembled and interconnected. The ignition sequencer assembly architecture allows for installation into a next higher-level assembly using a single, uniaxial, force. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/412539 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859563 | Karp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Jessica Godin Karp (Schenectady, New York); Xiaohui Chen (Schenectady, New York); Kashan Ali Shaikh (Clifton Park, New York); Mengli Wang (Rexford, New York); Ralf Lenigk (Schenectady, New York); Christine Lynne Surrette (Albany, New York) |
| ABSTRACT | A device and/or methodology are described that include a mechanism for separating erythrocytes from other constituents of blood and for purifying leukocytes from blood. The separation and purification aspects may be provided in separate components or within the same component. The separation aspect assists in separating erythrocytes (red blood cells) from other cells in blood, such as by aggregation of the red blood cells. A suitable aggregation device or device component uses chambers with at least one small dimension (e.g., a microfluidic chip) to control the interaction of the blood with a solution containing a high molecular weight polymer (e.g., dextran) to achieve separation. |
| FILED | Tuesday, December 01, 2015 |
| APPL NO | 14/956067 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 2313/18 (20130101) B01D 2313/50 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 3/502769 (20130101) B01L 2200/0647 (20130101) B01L 2300/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/491 (20130101) G01N 33/5002 (20130101) Original (OR) Class G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859596 | Reinke |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | John Reinke (Plymouth, Minnesota) |
| ABSTRACT | A vibrating beam accelerometer (VBA) with an in-plane pendulous proof mass, which may include one or more resonators, planar geometry, a single primary mechanical anchor between the support base and the VBA, a resonator connector structure connecting the resonators to the single primary anchor and a hinge flexure mechanically connecting the proof mass to the single primary anchor. The techniques of this disclosure specify how the resonators can be solidly attached to the single anchor without compromising performance caused by forces applied on or by the support base. The geometry of the VBA may prevent bias errors that may otherwise result from a force applied to the support base that reaches the mechanism of the VBA. An example of force applied to the support base, may include the thermal expansion mismatch between the material of the support base and the material of the VBA. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/041244 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/007 (20130101) B81B 2201/0235 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02259 (20130101) H03H 9/2473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859695 | Reed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Allen H. Reed (Bay St. Louis, Mississippi); William M. Sanders (New Orelans, Louisiana); David C. Young (Long Beach, Mississippi) |
| ABSTRACT | Embodiments relate to noncontact determination of nonlinearities. Initially, a first and second primary signal are preconditioned to produce a first and second tone capable of reaching a target granular media. Using a sound source, the first and second primary signals are emitted such that the first and second primary signals combine in a nonlinear fashion in the target granular media to produce low frequency acoustic tone that is a difference between the first and primary signals. An acoustic pulse is received by an acoustic receiver, and a quadratic nonlinearity coefficient and an acoustic pressure field are determined based on the acoustic pulse. At this stage, a sediment shear strength of the granular media is correlated to the quadratic nonlinearity coefficient to generate a shear strength lookup table. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/824711 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/539 (20130101) G01S 15/108 (20130101) Original (OR) Class G01S 15/8911 (20130101) G01S 15/8952 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 2210/144 (20130101) G01V 2210/584 (20130101) G01V 2210/588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860407 | Ly |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul Ly (Alhambra, California) |
| ABSTRACT | An apparatus and method for testing and troubleshooting systems, such as remote systems, have been developed that provide for a test control system configured to perform testing on a system under test. The test control system may include an electronic device operable to display a system fault code failure matrix visualization that may include fault codes and/or fault locations for one or more subsystems of a SUT. The test control system may also include an aggregated subsystem fault locations database that stores previously identified system or subsystem fault locations of the SUT that may lead to a source of an issue causing a particular fault code for the SUT, where the electronic device is operable to access the aggregated subsystem fault locations database to obtain the various previously identified fault locations. The previously identified system or subsystem fault locations may be based on previous testing of a system or subsystem. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870685 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/079 (20130101) Original (OR) Class G06F 11/0739 (20130101) G06F 11/0769 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860625 | Wroblewski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ronald John Wroblewski (San Diego, California) |
| ABSTRACT | A method for indexing semantic, non-transitory, computer-stored data comprising the following steps: storing the data in a database; representing the data in a structured framework having at least three elements derived from an ontology; expressing each element as a hierarchical-index value based on an ontology such that semantic information is embedded therein; combining the elements in a multi-dimensional index; and converting the multi-dimensional index into a one-dimensional index. |
| FILED | Tuesday, September 22, 2015 |
| APPL NO | 14/861965 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/283 (20190101) G06F 16/316 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860637 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Chengmin Ding (Chantilly, Virginia); Adam D. Dumey (Falls Church, Virginia); Allen B. Ginsberg (St. Petersburg, Florida); Elinna Shek (Aldie, Virginia) |
| ABSTRACT | Embodiments can provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement a media artifact annotation system, the method comprising inputting one or more relationships; for each of the one or more relationships, extracting, through an entity argument extraction module, one or more entity arguments; constructing, through a media query construction module, a media query using the one or more entity arguments; submitting the media query to a media search corpus; receiving search results comprising one or more media artifacts from the media search corpus; passing, through an annotation module, the search results to an annotator; receiving, through a response input module, one or more responses regarding each of the one or more media artifacts from the annotator; if the response for the media artifact is confirmatory, applying an annotation to the media artifact; and if the response for the media artifact is rejection, applying no annotation to the media artifact. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467283 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/48 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860916 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Serhan Ardanuc (Ithaca, New York); Jason T. Hoople (Ithaca, New York); Justin C. Kuo (Ithaca, New York) |
| ABSTRACT | Techniques, systems, and devices are described for implementing for implementing computation devices and artificial neurons based on nanoelectromechanical (NEMS) systems. In one aspect, a nanoelectromechanical system (NEMS) based computing element includes: a substrate; two electrodes configured as a first beam structure and a second beam structure positioned in close proximity with each other without contact, wherein the first beam structure is fixed to the substrate and the second beam structure is attached to the substrate while being free to bend under electrostatic force. The first beam structure is kept at a constant voltage while the other voltage varies based on an input signal applied to the NEMS based computing element. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/880261 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 2201/018 (20130101) B81B 2201/0214 (20130101) B81B 2201/0285 (20130101) B81B 2203/04 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/521 (20130101) G01S 7/52079 (20130101) G01S 15/02 (20130101) G01S 15/8925 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0002 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/0635 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 1/0094 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861152 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Cleveland, Ohio); Prateek Prasanna (Cleveland, Ohio) |
| ABSTRACT | Embodiments access a radiological image of tissue having a tumoral volume and a peritumoral volume; define a vasculature associated with the tumoral volume; generate a Cartesian two-dimensional (2D) vessel network representation; compute a first set of localized Hough transforms based on the Cartesian 2D vessel network representation; generate a first aggregated set of peak orientations based on the first set of Hough transforms; generate a spherical 2D vessel network representation; compute a second set of localized Hough transforms based on the spherical 2D vessel network representation; generate a second aggregated set of peak orientations based on the second set of Hough transforms; generate a vascular network organization descriptor based on the aggregated peak orientations; compute a probability that the tissue is a member of a positive class based on the vascular network organization descriptor; classify the ROI based on the probability; and display the classification. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/354504 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7253 (20130101) A61B 5/7267 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/628 (20130101) G06K 9/4633 (20130101) G06K 9/6228 (20130101) G06K 9/6277 (20130101) G06K 9/6286 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/62 (20170101) G06T 7/70 (20170101) G06T 7/187 (20170101) G06T 15/08 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20044 (20130101) G06T 2207/20061 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20116 (20130101) G06T 2207/20152 (20130101) G06T 2207/30064 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861219 | Haanpaa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cybernet Systems Corporation (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Cybernet Systems Corp. (Ann Arbor, Michigan) |
| INVENTOR(S) | Douglas Haanpaa (Dexter, Michigan); Charles J. Cohen (Ann Arbor, Michigan); Glenn J. Beach (Grass Lake, Michigan); Charles J. Jacobus (Ann Arbor, Michigan) |
| ABSTRACT | A system for performing object identification combines pose determination, EO/IR sensor data, and novel computer graphics rendering techniques. A first module extracts the orientation and distance of a target in a truth chip given that the target type is known. A second is a module identifies the vehicle within a truth chip given the known distance and elevation angle from camera to target. Image matching is based on synthetic image and truth chip image comparison, where the synthetic image is rotated and moved through a 3-Dimensional space. To limit the search space, it is assumed that the object is positioned on relatively flat ground and that the camera roll angle stays near zero. This leaves three dimensions of motion (distance, heading, and pitch angle) to define the space in which the synthetic target is moved. A graphical user interface (GUI) front end allows the user to manually adjust the orientation of the target within the synthetic images. The system also includes the generation of shadows and allows the user to manipulate the sun angle to approximate the lighting conditions of the test range in the provided video. |
| FILED | Tuesday, November 01, 2016 |
| APPL NO | 15/340519 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/3241 (20130101) G06K 9/6202 (20130101) Image Data Processing or Generation, in General G06T 3/20 (20130101) G06T 3/60 (20130101) G06T 7/20 (20130101) G06T 15/00 (20130101) G06T 15/10 (20130101) G06T 15/20 (20130101) Original (OR) Class G06T 2207/10012 (20130101) G06T 2207/30212 (20130101) G06T 2207/30248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861627 | Pelrine et al. |
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| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Ronald E. Pelrine (Longmont, Colorado); Annjoe Wong-Foy (Pacifica, California); Allen L. Hsu (Mountain View, California); Jose P. Joseph (Palo Alto, California) |
| ABSTRACT | A microrobot assembly system includes a substrate containing conductive traces formed into at least one holding zone and one moving zone, a diamagnetic layer on the substrate, at least two magnetic structures movable across the diamagnetic layer in response to voltages applied to the conductive traces, wherein the holding zone holds one of the magnetic structures and the moving zone allows another of the magnetic structures to attach to the magnetic structure being held. The system may include a plate spaced above the substrate and rails to guide the moving magnetic structures. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/565344 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0233 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0127 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 13/04 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/06 (20130101) H01F 7/0236 (20130101) H01F 7/0242 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861931 | Lichtenwalner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Daniel J. Lichtenwalner (Raleigh, North Carolina); Edward R. Van Brunt (Raleigh, North Carolina); Brett Hull (Raleigh, North Carolina) |
| ABSTRACT | Semiconductor devices include a semiconductor layer structure comprising a drift region that includes a wide band-gap semiconductor material. A shielding pattern is provided in an upper portion of the drift region in an active region of the device and a termination structure is provided in the upper portion of the drift region in a termination region of the device. A gate trench extends into an upper surface of the semiconductor layer structure. The semiconductor layer structure includes a semiconductor layer that extends above and at least partially covers the termination structure. |
| FILED | Thursday, December 08, 2016 |
| APPL NO | 15/372505 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/046 (20130101) H01L 29/063 (20130101) Original (OR) Class H01L 29/0615 (20130101) H01L 29/0619 (20130101) H01L 29/0623 (20130101) H01L 29/0696 (20130101) H01L 29/0878 (20130101) H01L 29/1037 (20130101) H01L 29/1095 (20130101) H01L 29/1608 (20130101) H01L 29/7397 (20130101) H01L 29/7811 (20130101) H01L 29/7813 (20130101) H01L 29/66068 (20130101) H01L 29/66734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861963 | Sriram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Saptharishi Sriram (Cary, North Carolina); Jennifer Qingzhu Gao (Raleigh, North Carolina); Jeremy Fisher (Raleigh, North Carolina); Scott Sheppard (Chapel Hill, North Carolina) |
| ABSTRACT | A gallium nitride based monolithic microwave integrated circuit includes a substrate, a channel layer on the substrate and a barrier layer on the channel layer. A recess is provided in a top surface of the barrier layer. First gate, source and drain electrodes are provided on the barrier layer opposite the channel layer, with a bottom surface of the first gate electrode in direct contact with the barrier layer. Second gate, source and drain electrodes are also provided on the barrier layer opposite the channel layer. A gate insulating layer is provided in the recess in the barrier layer, and the second gate electrode is on the gate insulating layer opposite the barrier layer and extending into the recess. The first gate, source and drain electrodes comprise the electrodes of a depletion mode transistor, and the second gate, source and drain electrodes comprise the electrodes of an enhancement mode transistor. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/663843 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/2003 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/66462 (20130101) Amplifiers H03F 1/0261 (20130101) H03F 3/21 (20130101) H03F 3/1935 (20130101) H03F 2200/451 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862016 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Gov't, as represented by Sec of Army (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Patrick J Taylor (Vienna, Virginia); Sudhir Trivedi (Nottingham, Maryland); Wendy L Sarney (Columbia, Maryland) |
| ABSTRACT | Provided among other things is an electrical device comprising: a first component that is a semiconductor or an electrical conductor; a second component that is an electrical conductor; and a strong, heat stable junction there between including an intermetallic bond formed of: substantially (a) tin (Sn) or a mixture of Sn and indium (In) thereof, and (b) substantially nickel (Ni). The junction can have an electrical contact resistance that is small compared to the resistance of the electrical device. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037835 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/29 (20130101) H01L 24/83 (20130101) H01L 35/08 (20130101) Original (OR) Class H01L 35/34 (20130101) H01L 2224/29083 (20130101) H01L 2224/29109 (20130101) H01L 2224/29111 (20130101) H01L 2224/29155 (20130101) H01L 2224/83895 (20130101) H01L 2224/83914 (20130101) H01L 2924/01322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862157 | Zhamu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Global Graphene Group, Inc. (Dayton, Ohio) |
| ASSIGNEE(S) | Global Graphene Group, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Aruna Zhamu (Springboro, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | Provided is a rechargeable alkali metal-sulfur cell comprising an anode layer, an electrolyte and a porous separator, a cathode layer, and a discrete anode-protecting layer disposed between the anode layer and the separator and/or a discrete cathode-protecting layer disposed between the separator and the cathode active material layer; wherein the anode-protecting layer or cathode-protecting layer comprises a conductive sulfonated elastomer composite having from 0.01% to 50% by weight of a conductive reinforcement material dispersed in a sulfonated elastomeric matrix material and the protective layer has a thickness from 1 nm to 50 μm, a fully recoverable tensile strain from 2% to 500%, a lithium ion conductivity from 10−7 S/cm to 5×10−2 S/cm, and an electrical conductivity from 10−7 S/cm to 100 S/cm. This battery exhibits an excellent combination of high sulfur content, high sulfur utilization efficiency, high energy density, and long cycle life. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/010965 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/583 (20130101) H01M 4/661 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 10/056 (20130101) H01M 10/3909 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862210 | Behdad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nader Behdad (Oregon, Wisconsin); John H. Booske (McFarland, Wisconsin); Hung Thanh Luyen (Madison, Wisconsin); Zongtang Zhang (Madison, Wisconsin) |
| ABSTRACT | A multiple band phase shifter includes a first dielectric layer, a conductive layer, a second dielectric layer, and for each central operating frequency of a plurality of central operating frequencies, a switch, a plurality of vias, and a conducting pattern layer. Each via is formed of a conductive material that extends through the first dielectric layer, through a third dielectric material formed in and through the conductive layer, and through the second dielectric layer and is connected to a first throw arm or a second throw arm of the switch. The conducting pattern layer includes conductors electrically connected to a distinct via. An electric polarization of a reflected electromagnetic wave is rotated by 90 degrees when the switch is positioned in the first conducting position and the electric polarization of the reflected electromagnetic wave is rotated by −90 degrees when the switch is positioned in the second conducting position. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/362947 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/34 (20130101) Original (OR) Class H01Q 15/24 (20130101) H01Q 19/104 (20130101) H01Q 21/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862692 | Shahrjerdi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Davood Shahrjerdi (New York, New York); Abdullah Alharbi (Brooklyn, New York) |
| ABSTRACT | An article of manufacture includes a substrate and a security primitive deposited on the substrate. The security primitive includes a transition metal dichalcogenide having a varying thickness. According to various embodiments, the transition metal dichalcogenide comprises a chalcogen atom (X) selected from the group consisting of S, Se, and Te and a transition metal (M) selected from the group consisting of Mo, W, Hf, and Zr. The security primitive is pixelated into a plurality of discrete regions having different luminescence. A security primitive key includes a first set of data values corresponding to a first set of coordinates of a first region and a second set of data values corresponding to a second set of coordinates of a second region. In some embodiments, the security primitive key is digitally captured through an optical reader and verified by querying a database. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847460 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) B05D 5/061 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/681 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862865 | Lane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daria Christine Lane (San Diego, California); Enrique Salvador Leon (San Diego, California); Francisco Chiu Tacliad, III (San Diego, California); Dmitriy Ivanovich Obukhov (San Diego, California) |
| ABSTRACT | An unmanned autonomous device includes an isolation kernel having plurality of drivers respectively dedicated to a plurality of subsystems. The drivers are configured to facilitate communication between the subsystems. A gateway in the unmanned autonomous device is configured to control routing of data between the subsystems via the drivers respectively dedicated to the subsystems, such that data is only allowed to be passed between the subsystems along predefined routes. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/015012 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/0015 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/02 (20130101) H04L 29/06068 (20130101) H04L 63/02 (20130101) H04L 63/0245 (20130101) Original (OR) Class H04L 63/1408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862918 | Benyo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts); Florida Institute of Technology (Melbourne, Florida) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts); Florida Institute of Technology, Inc. (Melbourne, Florida) |
| INVENTOR(S) | Brett Benyo (Ayer, Massachusetts); Michael Atighetchi (Framingham, Massachusetts); Fusun Yaman (Arlington, Massachusetts); Marco M. Carvalho (Satellite Beach, Florida); Thomas C. Eskridge (Satellite Beach, Florida) |
| ABSTRACT | A decision engine includes: a genetic algorithm framework including a knowledge base of standard configurations, a candidate selector generator and a selector to select a candidate configuration from a plurality of preferred standard configurations in response to the candidate selector generator; a parallelized reasoning framework including an attack surface reasoning algorithm module to compute the security and cost tradeoffs of an attack surface associated with each candidate configuration; and a user interface framework including a web service engine where users can interact and provide feedback on direction of an evolution used in a genetic algorithm search for evolving defenses. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958359 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/56 (20130101) G06F 21/552 (20130101) G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1416 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101) Wireless Communication Networks H04W 12/1204 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862938 | Mitchell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Tyler J. Mitchell (Ithaca, New York); Scott Aloisio (Willseyville, New York); Matthew A. Stillerman (Ithaca, New York); Valentino Felipe (Campbell, California); Judson Powers (Ithaca, New York) |
| ABSTRACT | In general, this disclosure describes media stream transmission techniques for a computing device. The computing device captures a first media item and identifies a primary portion of the first media item and a secondary portion of the first media item different than the primary portion. The computing device applies a first compression algorithm to the primary portion of the first media item to generate a compressed primary portion. The computing device applies a second compression algorithm to the secondary portion of the first media item to generate a compressed secondary portion, where a data compression ratio of the second compression algorithm is greater than a data compression ratio of the first compression algorithm. The computing device transmits, to a central computing device, the compressed primary portion of the first media item and the compressed secondary portion of the first media item. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432457 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 65/601 (20130101) Original (OR) Class H04L 65/607 (20130101) H04L 65/608 (20130101) Pictorial Communication, e.g Television H04N 19/182 (20141101) H04N 19/186 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10858360 | Bensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Merck Sharp and Dohme Corp. (North Wales, Pennsylvania); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | MERCK SHARP and DOHME CORP. (Rahway, New Jersey); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh T. Lam (San Diego, California); Suk J. Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie W. Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (Marlborough, California); Sergio E. Wong (Tracy, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California) |
| ABSTRACT | Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/643760 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858404 | Cushman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF UNIVERSITY (Reno, Nevada) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
| INVENTOR(S) | John C. Cushman (Reno, Nevada); Sung Don Lim (Reno, Nevada); Won Cheol Yim (Reno, Nevada) |
| ABSTRACT | Disclosed herein are method of altering CAM pathways in plants. In some examples, a disclosed method includes overexpressing one or more genes encoding one or more enzymes that carry out the basic biochemical sequence of nocturnal CO2 fixation (carboxylation) into C4 acids (malate), store C4 acids in the vacuole of the plant, and/or then decarboxylate and refix the released CO2 by C3 photosynthesis during the subsequent day in a plant cell, thereby altering CAM in the plant cell. Also disclosed herein are isolated polynucleotide sequences, transformation vectors, transgenic plant cells, plant part, and plants. The disclosed methods and compositions can be used to improve the water-use efficiency and drought tolerance and durability of plants, such as in plants in arid environments, and also enhance the ability of plants to perform. |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/027145 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/00 (20130101) A01H 5/00 (20130101) Peptides C07K 14/415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858581 | Dou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Letian Dou (West Lafayette, Indiana); Minliang Lai (El Cerrito, California); Yiming Yang (Walnut Creek, California); Peidong Yang (Kensington, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Letian Dou (West Lafayette, Indiana); Minliang Lai (El Cerrito, California); Yiming Yang (Walnut Creek, California); Peidong Yang (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to heterojunctions in halide perovskite nanostructures. In one aspect, a nanostructure comprises a first region and a second region. The first region comprises ABX3, with A being selected from a group consisting of Cs and Rb, with B being selected from a group consisting of Sn and Pb, and with X being selected from a group consisting of Br, Cl, and Br and Cl. The second region comprises ABY3, with Y being selected from a group consisting of Br, I, and Br and I. Compositions of the first region of the nanostructure and the second region of the nanostructure are different. |
| FILED | Monday, October 09, 2017 |
| APPL NO | 15/727823 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/665 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858664 | Kaeppler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Shawn Kaeppler (Oregon, Wisconsin); Natalia de Leon (Middleton, Wisconsin); Jillian M. Foerster (Des Moines, Iowa); German Muttoni (Madison, Wisconsin) |
| ABSTRACT | The present invention provides compositions and methods for modulating the reproductive transition in plants, such as grasses (e.g., maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G171650 (zmm22) or homologs thereof. Modulation of expression of one or more additional genes which affect reproductive transition such as zagl1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G171650 are also contemplated, as are transgenic plants, and products produced therefrom, that demonstrate altered development such as extended flowering time and display associated phenotypes such as enhanced yield of vegetative biomass, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production. |
| FILED | Wednesday, June 04, 2014 |
| APPL NO | 14/296352 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858687 | Bonito et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Gregory Bonito (East Lansing, Michigan); Zhi-Yan Du (East Lansing, Michigan); Christoph Benning (East Lansing, Michigan) |
| ABSTRACT | This application describes consortium between fungi and algae, where the algae are incorporated within hyphae of the fungi. The fungi, the algae, or both can be modified to express heterologous lipid synthesizing enzymes. Incorporation of algae into fungi facilitates harvesting of the algae and products produced by the consortia. Such consortia are robust. For example, the fungi and algae can symbiotically provide nutrients to each other and are tolerant of environmental stresses. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058632 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/14 (20130101) C12N 9/00 (20130101) C12N 9/0004 (20130101) C12N 15/8205 (20130101) C12N 15/8245 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/649 (20130101) C12P 7/6463 (20130101) C12P 39/00 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/66 (20130101) C12R 1/72 (20130101) C12R 1/77 (20130101) C12R 1/80 (20130101) C12R 1/84 (20130101) C12R 1/85 (20130101) C12R 1/89 (20130101) C12R 1/885 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858692 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kun Zhang (Brighton, Massachusetts); Joseph Chou (Jamaica Plain, Massachusetts) |
| ABSTRACT | Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945192 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858698 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Liangcai Gu (Boston, Massachusetts) |
| ABSTRACT | Methods for attaching barcodes to polypeptides are provided. Methods for detecting molecular interactions at the single molecule level are provided. Embodiments of the invention are directed to a ONA barcoded protein array technology for parallel protein interaction profiling on a single molecule basis. DNA barcodes are attached to proteins collectively via ribosome display or individually via enzymatic conjugation. Novel methods are described herein that measure protein interactions based on the statistical analysis of co-localized polonies arising from barcoding DNAs of interacting proteins. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 15/128145 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2521/107 (20130101) C12Q 2563/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859208 | Tamburello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | David A. Tamburello (Aiken, South Carolina); Anthony J. McWilliams (Aiken, South Carolina) |
| ABSTRACT | Vessel assemblies, heat transfer units for prefabricated vessels, and methods for heat transfer prefabricated vessel are provided. A heat transfer unit includes a central rod, and a plurality of peripheral rods surrounding the central rod and connected to the central rod. The plurality of peripheral rods are movable between a first collapsed position and a second bowed position, wherein in the second bowed position a midpoint of each of the plurality of peripheral rods is spaced from the central rod relative to in the first position. The heat transfer unit further includes a heat transfer element connected to one of the plurality of peripheral rods. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994446 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 13/002 (20130101) Original (OR) Class F17C 2227/0304 (20130101) F17C 2227/0309 (20130101) F17C 2227/0341 (20130101) F17C 2227/0397 (20130101) F17C 2250/0631 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0206 (20130101) F28D 1/0472 (20130101) F28D 2001/0273 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/24 (20130101) F28F 1/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859264 | Fetvedt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 8 Rivers Capital, LLC (Durham, North Carolina) |
| ASSIGNEE(S) | 8 Rivers Capital, LLC (Durham, North Carolina) |
| INVENTOR(S) | Jeremy Eron Fetvedt (Raleigh, North Carolina); Xijia Lu (Durham, North Carolina); Brent Gregory (Scottsdale, Arizona); Chris Bonilha (Phoenix, Arizona); James Lenertz (Scottsdale, Arizona); Stefan Tschirren (Laufen, Switzerland); Hassan Abdulsater (Gilbert, Arizona) |
| ABSTRACT | The present disclosure relates to apparatuses and methods that are useful for one or more aspects of a power production plant. More particularly, the disclosure relates to combustor apparatuses and methods for a combustor adapted to utilize different fuel mixtures derived from gasification of a solid fuel. Combustion of the different fuel mixtures within the combustor can be facilitated by arranging elements of the combustor controlled so that a defined set of combustion characteristics remains substantially constant across a range of different fuel mixtures. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/869978 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 43/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/22 (20130101) Methods or Apparatus for Combustion Using Only Solid Fuel F23B 90/06 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 2202/50 (20130101) Burners F23D 14/24 (20130101) F23D 2214/00 (20130101) Cremation Furnaces; Consuming Waste Products by Combustion F23G 5/027 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) F23L 2900/07002 (20130101) Casings, Linings, Walls or Doors Specially Adapted for Combustion Chambers, e.g Firebridges; Devices for Deflecting Air, Flames or Combustion Products in Combustion Chambers; Safety Arrangements Specially Adapted for Combustion Apparatus; Details of Combustion Chambers, Not Otherwise Provided for F23M 5/085 (20130101) Original (OR) Class Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) F23R 3/12 (20130101) F23R 3/36 (20130101) F23R 2900/03041 (20130101) F23R 2900/03043 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859324 | Wirz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard E. Wirz (Los Angeles, California); Parker A. Wells (Oakland, California) |
| ABSTRACT | A thermal energy storage (TES) system includes a plurality of closely packed TES modules, each TES module having a shell enclosing a plurality of sealed tubes that each contain a TES media. A computer-controlled flow control system includes a flow distributor, for example a flow distributor having a plenum configured to receive a heat transfer fluid (HTF), and a plurality of control valves controlled by the computer to controllably distribute the HTF from the plenum to the plurality of TES modules. Sensor data from the TES modules, for example temperature, pressure, and/or flow data, is provided to the computer. In some embodiments the plenum includes two or more compartments with separate HTF flow ports, which may be provided to the controller at different temperatures. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 16/083450 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 17/04 (20130101) Original (OR) Class F28D 20/028 (20130101) F28D 2020/0004 (20130101) F28D 2020/006 (20130101) F28D 2020/0069 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859480 | Koester et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | David J. Koester (Nashville, Tennessee); Douglas Adams (Brentwood, Tennessee); Raymond Martin Bond (Nashville, Tennessee); Garrett W. Thorne (Nashville, Tennessee); Janette Jaques Meyer (Nashville, Tennessee) |
| ABSTRACT | A method for determining a linear density of a carbon fiber tow. The method includes providing a pulse of air directed toward the carbon fiber tow, determining, via a first sensor, an air pressure of the pulse of air, and measuring, via a second sensor, a displacement of the carbon fiber tow in response to the pulse of air directed toward the carbon fiber tow. The method further includes calculating, via a controller, a linear density of the carbon fiber tow based on the air pressure and the displacement, and outputting, via the controller, the linear density. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/920175 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 9/00 (20130101) G01N 9/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859721 | Stracuzzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David John Stracuzzi (Albuquerque, New Mexico); Matthew Gregor Peterson (Albuquerque, New Mexico); Charles Theodore Vollmer (Fort Collins, Colorado) |
| ABSTRACT | A computer-implemented method of enhancing a computer to estimate an uncertainty of an onset of a signal of interest in time-series noisy data. A first mathematical model of first time series data that contains only noise is calculated. A second mathematical model of second time series data that contains the noise and an onset of a signal of interest in the second time series data is calculated. A difference is evaluated between a first combination, being the first mathematical model and the second mathematical model, and a second combination, being the first time series data and the second time series data, wherein evaluating is performed using a generalized entropy metric. A specific time when an onset of the signal of interest occurs is estimated from the difference. An “a posteriori” distribution is derived for an uncertainty of the specific time at which the onset occurs. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885255 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/282 (20130101) Original (OR) Class G01V 1/366 (20130101) G01V 2210/30 (20130101) G01V 2210/612 (20130101) G01V 2210/667 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/0053 (20130101) G06K 9/0055 (20130101) G06K 9/6268 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860418 | Kalamatianos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Sunnyvale, California) |
| INVENTOR(S) | John Kalamatianos (Boxborough, Massachusetts); Michael Mantor (Orlando, Florida); Sudhanva Gurumurthi (Austin, Texas) |
| ABSTRACT | A system and method for protecting memory instructions against faults are described. The system and method include converting the slave instructions to dummy operations, modifying memory arbiter to issue up to N master and N slave global/shared memory instructions per cycle, sending master memory requests to memory system, using slave requests for error checking, entering master requests to the GM/LM FIFO, storing slave requests in a register, and comparing the entered master requests with the stored slave requests. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 16/378287 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1064 (20130101) Original (OR) Class G06F 11/1629 (20130101) G06F 11/1641 (20130101) G06F 11/1654 (20130101) G06F 12/0866 (20130101) G06F 2212/281 (20130101) G06F 2212/403 (20130101) G06F 2212/1032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860489 | Das et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Shomit N. Das (Austin, Texas); Matthew Tomei (Champaign, Illinois); David A. Wood (Austin, Texas) |
| ABSTRACT | Techniques are disclosed for designing cache compression algorithms that control how data in caches are compressed. The techniques generate a custom “byte select algorithm” by applying repeated transforms applied to an initial compression algorithm until a set of suitability criteria is met. The suitability criteria include that the “cost” is below a threshold and that a metadata constraint is met. The “cost” is the number of blocks that can be compressed by an algorithm as compared with the “ideal” algorithm. The metadata constraint is the number of bits required for metadata. |
| FILED | Wednesday, October 31, 2018 |
| APPL NO | 16/176828 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0871 (20130101) Original (OR) Class G06F 30/00 (20200101) G06F 2212/401 (20130101) Coding; Decoding; Code Conversion in General H03M 7/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860526 | Bowen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Benjamin P. Bowen (Berkeley, California); Oliver Ruebel (Berkeley, California) |
| ABSTRACT | Disclosed are systems and software that provide a high-performance, extensible file format and web API for remote data access and a visual interface for data viewing, query, and analysis. The described system can support storage of raw spectroscopic data such as neural recording data, MSI data, metadata, and derived analyses in a single, self-describing format that may be compatible by a large range of analysis software. |
| FILED | Wednesday, November 27, 2013 |
| APPL NO | 14/091986 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/11 (20190101) Original (OR) Class G06F 19/321 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861172 | Matzner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Shari Matzner (Sequim, Washington) |
| ABSTRACT | Described herein are sensing methods, sensor systems, and non-transitory, computer-readable, storage media having programs for long-duration, continuous monitoring of flying objects during the day or the night and regardless of weather conditions. The methods and systems are computationally efficient and can provide compact, three-dimensional representations of motion from the observed object. A 3D track of the flying object can be generated from a point-matched pair of stereo composite motion track images and not directly from the videos, wherein each composite motion track image is based on a composite of a plurality of video frames composited in part according to video frame numbers. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/203115 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0025 (20130101) G01J 2005/0077 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) G06K 9/6202 (20130101) G06K 9/6212 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/97 (20170101) G06T 7/285 (20170101) Original (OR) Class G06T 7/593 (20170101) G06T 2207/10021 (20130101) Pictorial Communication, e.g Television H04N 13/122 (20180501) H04N 13/279 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861995 | Sie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Edbert J. Sie (Stanford, California); Clara M. Nyby (Stanford, California); Sri C D Pemmaraju (Stanford, California); Xijie Wang (Stanford, California); Aaron M. Lindenberg (Stanford, California) |
| ABSTRACT | A method of operating a device includes: (1) providing a film of a semimetal in a first topological phase; and (2) inducing interlayer shear oscillation of the semimetal within the film, wherein the interlayer shear oscillation induces the semimetal to transition to a different, second topological phase. |
| FILED | Tuesday, September 03, 2019 |
| APPL NO | 16/559331 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) Original (OR) Class H01L 31/032 (20130101) H01L 49/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862163 | Fenton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC- (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Kyle R. Fenton (Albuquerque, New Mexico); Ganesan Nagasubramanian (Albuquerque, New Mexico); Chad Staiger (Albuquerque, New Mexico); Harry Pratt (Albuquerque, New Mexico); Kevin Leung (Albuquerque, New Mexico); Susan Rempe (Albuquerque, New Mexico); Mangesh Chaudhari (Albuquerque, New Mexico); Travis Mark Anderson (Albuquerque, New Mexico) |
| ABSTRACT | Organosilicon electrolytes exhibit several important properties for use in lithium carbon monofluoride batteries, including high conductivity/low viscosity and thermal/electrochemical stability. Conjugation of an anion binding agent to the siloxane backbone of an organosilicon electrolyte creates a bi-functional electrolyte. The bi-functionality of the electrolyte is due to the ability of the conjugated polyethylene oxide moieties of the siloxane backbone to solvate lithium and thus control the ionic conductivity within the electrolyte, and the anion binding agent to bind the fluoride anion and thus facilitate lithium fluoride dissolution and preserve the porous structure of the carbon monofluoride cathode. The ability to control both the electrolyte conductivity and the electrode morphology/properties simultaneously can improve lithium electrolyte operation. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/409845 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/385 (20130101) H01M 4/5835 (20130101) H01M 10/052 (20130101) H01M 10/0564 (20130101) Original (OR) Class H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862168 | Wessells et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Natron Energy, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Natron Energy, Inc. (Santa Clara, California) |
| INVENTOR(S) | Colin Deane Wessells (Palo Alto, California); Shahrokh Motallebi (Los Gatos, California) |
| ABSTRACT | A system and method for stabilizing electrodes against dissolution and/or hydrolysis including use of cosolvents in liquid electrolyte batteries for three purposes: the extension of the calendar and cycle life time of electrodes that are partially soluble in liquid electrolytes, the purpose of limiting the rate of electrolysis of water into hydrogen and oxygen as a side reaction during battery operation, and for the purpose of cost reduction. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/215339 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/36 (20130101) H01M 4/58 (20130101) H01M 4/60 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/628 (20130101) H01M 4/9008 (20130101) H01M 8/188 (20130101) H01M 10/08 (20130101) H01M 10/36 (20130101) H01M 10/44 (20130101) H01M 10/056 (20130101) H01M 10/345 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2220/10 (20130101) H01M 2220/20 (20130101) H01M 2250/10 (20130101) H01M 2250/20 (20130101) H01M 2300/0002 (20130101) H01M 2300/002 (20130101) H01M 2300/004 (20130101) H01M 2300/0025 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101) H01M 2300/0091 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 90/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862171 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | POLYPLUS BATTERY COMPANY (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Richard L. Swisher (Northfield, Minnesota) |
| ABSTRACT | Methods for making solid-state laminate electrode assemblies include methods to prevent devitrifying and damaging a lithium ion conducting sulfide glass substrate during thermal evaporation of lithium metal, as well as methods for making thin extruded lithium metal foils. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/341874 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/0423 (20130101) H01M 4/0471 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 10/0585 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862692 | Shahrjerdi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Davood Shahrjerdi (New York, New York); Abdullah Alharbi (Brooklyn, New York) |
| ABSTRACT | An article of manufacture includes a substrate and a security primitive deposited on the substrate. The security primitive includes a transition metal dichalcogenide having a varying thickness. According to various embodiments, the transition metal dichalcogenide comprises a chalcogen atom (X) selected from the group consisting of S, Se, and Te and a transition metal (M) selected from the group consisting of Mo, W, Hf, and Zr. The security primitive is pixelated into a plurality of discrete regions having different luminescence. A security primitive key includes a first set of data values corresponding to a first set of coordinates of a first region and a second set of data values corresponding to a second set of coordinates of a second region. In some embodiments, the security primitive key is digitally captured through an optical reader and verified by querying a database. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847460 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) B05D 5/061 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/681 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10856806 | Iskander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Magdy F. Iskander (Honolulu, Hawaii); Ruthsenne R. G. Perron (Waipahu, Hawaii) |
| ABSTRACT | A system and method for monitoring lung water content of a patient. The system may include at least two microwave sensors and a processor. The system may transmit one or more microwave signals into the thorax of a patient using one or more of the microwave sensors. The system may then receive one or more of the microwave signals using one or more of the microwave sensors. The one or more received microwave signals may each have at least one associated frequency component with a magnitude and a phase. The system may analyze the phase of one or more received microwave signals to monitor changes in the lung water content. The system may analyze the magnitude of one or more received microwave signals to determine whether the lung water content is increasing or decreasing. |
| FILED | Monday, August 17, 2015 |
| APPL NO | 14/828323 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/08 (20130101) A61B 5/021 (20130101) A61B 5/024 (20130101) A61B 5/029 (20130101) A61B 5/0205 (20130101) A61B 5/0507 (20130101) A61B 5/0809 (20130101) A61B 5/0816 (20130101) A61B 5/4878 (20130101) Original (OR) Class A61B 5/6823 (20130101) A61B 5/7246 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) A61B 5/7282 (20130101) A61B 2560/0223 (20130101) A61B 2562/0228 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856815 | Pereira et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| INVENTOR(S) | Francisco Pereira (Jersey City, New Jersey); Bin Lou (West Windsor, New Jersey); Angeliki Lazaridou (Artemida, Greece) |
| ABSTRACT | By way of introduction, the present embodiments described below include apparatuses and methods for generating natural language representations of mental content from functional brain images. Given functional imaging data acquired while a subject reads a text passage, a reconstruction of the text passage is produced. Linguistic semantic vector representations are assigned (1301) to words, phrases or sentences to be used as training stimuli. Basis learning is performed (1305), using brain imaging data acquired (1303) when a subject is exposed to the training stimuli and the corresponding semantic vectors for training stimuli, to learn an image basis directly. Semantic vector decoding (1309) is performed with functional brain imaging data for test stimuli and using the image basis to generate a semantic vector representing the test imaging stimuli. Text generation (1311) is then performed using the decoded semantic vector representing the test imaging stimuli. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/752276 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) A61B 5/04842 (20130101) A61B 5/7267 (20130101) Original (OR) Class Electric Digital Data Processing G06F 40/30 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857243 | Du et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Xuewen Du (Waltham, Massachusetts); Jie Zhou (Waltham, Massachusetts); Bing Xu (Newton, Massachusetts) |
| ABSTRACT | The invention relates to an enzymatically responsive product that includes an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. Compositions containing the enzymatically responsive product, and the use thereof for separating distinct types of mammalian cells (e.g., cancer cells from normal cells), for treating a cancerous condition, and imaging cancer cells are also disclosed. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 15/303117 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00345 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 41/0052 (20130101) A61K 45/06 (20130101) A61K 47/52 (20170801) A61K 47/64 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/1866 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/54326 (20130101) G01N 33/57492 (20130101) G01N 2333/916 (20130101) G01N 2440/14 (20130101) G01N 2440/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857669 | Rus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniela Rus (Weston, Massachusetts); John W. Romanishin (Medford, Massachusetts); Kyle W. Gilpin (Cambridge, Massachusetts) |
| ABSTRACT | A modular robotic system that includes a plurality of self-configuring robots. Each self-configuring robot includes a frame structure having a plurality of cylindrical bonding magnets positioned along the edges of the frame structure. The frame structure includes magnetic, non-gendered, hinges on any of the edges of the frame. The hinges provide enough force to maintain a pivot axis through various motions. The cylindrical bonding magnets are free to rotate allowing for multiple self-configurations with other like self-configuring robots. A movement generator is positioned within the frame structure that pivots to generate multi-axis movement allowing both robust self-reconfiguration with the other self-configuring robots and independent locomotion. |
| FILED | Wednesday, October 30, 2013 |
| APPL NO | 14/067132 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Toys, e.g Tops, Dolls, Hoops or Building Blocks A63H 29/20 (20130101) A63H 33/26 (20130101) A63H 33/046 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857670 | Rus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniela Rus (Weston, Massachusetts); John W. Romanishin (Medford, Massachusetts); Kyle W. Gilpin (Cambridge, Massachusetts) |
| ABSTRACT | A modular robotic system that includes a plurality of self-configuring robots. Each self-configuring robot includes a frame structure having a plurality of cylindrical bonding magnets positioned along the edges of the frame structure. The frame structure includes magnetic, non-gendered, hinges on any of the edges of the frame. The hinges provide enough force to maintain a pivot axis through various motions. The cylindrical bonding magnets are free to rotate allowing for multiple self-configurations with other like self-configuring robots. A movement generator is positioned within the frame structure that pivots to generate multi-axis movement allowing both robust self-reconfiguration with the other self-configuring robots and independent locomotion. |
| FILED | Monday, July 18, 2016 |
| APPL NO | 15/212753 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Toys, e.g Tops, Dolls, Hoops or Building Blocks A63H 29/20 (20130101) A63H 33/26 (20130101) A63H 33/046 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858239 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annadale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293455 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858240 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annadale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293457 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858263 | Weller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jon Mark Weller (Phoenix, Arizona); Candace Chan (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jon Mark Weller (Phoenix, Arizona); Candace Chan (Phoenix, Arizona) |
| ABSTRACT | Nanosized cubic lithium lanthanum zirconate is synthesized by forming a solution including an organic compound and compounds of lithium, lanthanum, and zirconium; drying the solution to yield a solid; and heating the solid in the presence of oxygen to pyrolyze the organic compound to yield a product comprising nanosized cubic lithium lanthanum zirconate. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/009518 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/76 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) H01M 10/0562 (20130101) H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858318 | Frost et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | John Wesley Frost (Okemos, Michigan); Peng Zhang (Piscataway, New Jersey) |
| ABSTRACT | Methods for producing cycloaddition products comprising: reacting a diene with a dienophile in the presence of one or more boron-based catalysts of Formula I or Formula II are provided. In particular, the methods can be used to prepare 4-methyl-3-cyclohexene-1-carboxylic acid and 3-methyl-3-cyclohexene-1-carboxylic acid, including bio-based versions thereof. The cycloaddition products can be advantageously used in the production of terephthalic acid and isophthalic acid, and ultimately, poly(ethylene terephthalate), and bio-based versions thereof. BOBL4 Formula II |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/762822 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/14 (20130101) B01J 31/146 (20130101) B01J 2231/326 (20130101) Acyclic or Carbocyclic Compounds C07C 51/347 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 61/22 (20130101) C07C 61/22 (20130101) C07C 61/28 (20130101) C07C 61/29 (20130101) C07C 61/39 (20130101) C07C 62/36 (20130101) C07C 2601/16 (20170501) C07C 2602/42 (20170501) C07C 2602/44 (20170501) Heterocyclic Compounds C07D 209/18 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858334 | Stahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Shannon Stahl (Madison, Wisconsin); Stephen Tereniak (Madison, Wisconsin) |
| ABSTRACT | An oxidative homocoupling method of synthesizing certain 2,2′-bithiophenes from thiophenes using oxygen as the terminal oxidant is disclosed. In non-limiting examples, the method uses oxygen along with a catalytic system that includes palladium, an assistive ligand, and a non-palladium metal additive to catalyze one of the following reactions: Associated catalytic systems and compositions are also disclosed. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243394 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/04 (20130101) B01J 31/181 (20130101) B01J 31/183 (20130101) B01J 31/184 (20130101) B01J 31/1815 (20130101) B01J 31/1825 (20130101) B01J 31/2239 (20130101) B01J 31/2409 (20130101) B01J 2231/46 (20130101) B01J 2531/16 (20130101) B01J 2531/0205 (20130101) B01J 2531/824 (20130101) B01J 2531/842 (20130101) B01J 2540/10 (20130101) B01J 2540/22 (20130101) B01J 2540/40 (20130101) B01J 2540/225 (20130101) Heterocyclic Compounds C07D 277/32 (20130101) C07D 333/22 (20130101) Original (OR) Class C07D 333/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858410 | Polt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Robin Polt (Tucson, Arizona); Evan M. Jones (Tucson, Arizona); Bobbi Anglin (Tucson, Arizona); Michael L. Heien (Tucson, Arizona); John M. Streicher (Tucson, Arizona) |
| ABSTRACT | Glycosylated peptides with glycosylation at or near the C-terminal domain of the peptide have an enhanced ability to cross the blood brain barrier (BBB) and/or enhanced half-lives. These glycosylated peptides may be used as drugs. For example, a PACAP peptide with a C-terminal glycosylation, e.g., in lieu of the terminal leucine, functions as a PAC1 agonist with enhanced ability to cross the BBB and with enhanced half-life. The peptides can have a pseudoproline residue with glycosylation at or near the C-terminal domain. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752157 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858681 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California); Stephanie Galanie (Palo Alto, California) |
| ABSTRACT | Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes involved in synthetic pathways from starting compounds to BIAs of the host cell. Also provided are methods of producing the BIAs of interest by culturing the host cells under culture conditions that promote expression of enzymes encoded by the heterologous coding sequences of the host cells. Aspects of the invention further include compositions, e.g., host cells, starting compounds and kits, etc., that find use in methods of the invention. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/978005 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) C12N 9/1007 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/18 (20130101) C12P 17/182 (20130101) Original (OR) Class Enzymes C12Y 121/03003 (20130101) C12Y 201/0114 (20130101) C12Y 201/01116 (20130101) C12Y 201/01128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858687 | Bonito et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Gregory Bonito (East Lansing, Michigan); Zhi-Yan Du (East Lansing, Michigan); Christoph Benning (East Lansing, Michigan) |
| ABSTRACT | This application describes consortium between fungi and algae, where the algae are incorporated within hyphae of the fungi. The fungi, the algae, or both can be modified to express heterologous lipid synthesizing enzymes. Incorporation of algae into fungi facilitates harvesting of the algae and products produced by the consortia. Such consortia are robust. For example, the fungi and algae can symbiotically provide nutrients to each other and are tolerant of environmental stresses. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058632 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/14 (20130101) C12N 9/00 (20130101) C12N 9/0004 (20130101) C12N 15/8205 (20130101) C12N 15/8245 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/649 (20130101) C12P 7/6463 (20130101) C12P 39/00 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/66 (20130101) C12R 1/72 (20130101) C12R 1/77 (20130101) C12R 1/80 (20130101) C12R 1/84 (20130101) C12R 1/85 (20130101) C12R 1/89 (20130101) C12R 1/885 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859437 | Scholtz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chromation, Inc. (New York, New York) |
| ASSIGNEE(S) | CHROMATION, INC. (Bronx, New York) |
| INVENTOR(S) | James Scholtz (Jamesport, New York); Nadia Pervez (Houston, Texas); Ioannis Kymissis (New York, New York); Michael Gazes (Forest Hills, New York) |
| ABSTRACT | An apparatus includes a substrate transmissive of electromagnetic energy of at least a plurality of wavelengths, having a first end, a second end, a first major face, a second major face, at least one edge, a length, a width, and a thickness, at least a first output optic that outputs electromagnetic energy the substrate; and a first input optic oriented and positioned to provide electromagnetic energy into the substrate via at least one of the first or the second major face of the substrate. The first output optic is laterally spaced from the first input optic. A number of reflectors and optional absorbers may be positioned proximate the first major face and/or the second major face to structure electromagnetic energy and/or to translate such from the first input optic to the first output optic. The apparatus may be part of a spectrometer or other optical system. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/303373 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0208 (20130101) Original (OR) Class G01J 3/0237 (20130101) G01J 3/0254 (20130101) Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 6/29365 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/377 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859473 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Chang-Yu Wu (Gainesville, Florida); Xiao Jiang (Gainesville, Florida); Maohua Pan (Gainesville, Florida); John Lednicky (Gainesville, Florida); Alexandros Demetrios Theodore (Plantation, Florida); Zhonghui Hugh Fan (Gainesville, Florida); Nima Afshar Mohajer (Baltimore, Maryland) |
| ABSTRACT | Described herein are bioaerosol detection systems and methods of use. |
| FILED | Thursday, April 06, 2017 |
| APPL NO | 16/089099 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/70 (20130101) C12Q 1/70 (20130101) C12Q 2531/119 (20130101) C12Q 2531/143 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) Original (OR) Class G01N 1/2214 (20130101) G01N 33/54306 (20130101) G01N 33/54366 (20130101) G01N 33/56983 (20130101) G01N 2001/2223 (20130101) G01N 2001/2282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859500 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Wei David Wei (Gainesville, Florida); Jingjing Qiu (Daly City, California) |
| ABSTRACT | Embodiments of the present disclosure provide plasmonic structures, methods of making plasmonic structures, and the like. |
| FILED | Monday, April 17, 2017 |
| APPL NO | 16/093152 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 33/553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859538 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Shrinivas G. Joshi (Brookfield, Wisconsin); Meghna Saikia (Milwaukee, Wisconsin) |
| ABSTRACT | Passive wireless sensors include an antenna. The antenna receives a combined signal. The combined signal includes a low frequency modulating signal modulated on a high frequency carrier wave. A demodulator receives the combined signal and extracts the modulating signal. A sensor receives the extracted modulating signal and produces an output signal with a time delay indicative of a property to be sensed. A modulator receives the output signal and the high frequency carrier wave and modulates the output signal onto the high frequency carrier wave to create a combined output signal broadcast by the antenna. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/097743 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/66 (20130101) G01F 1/662 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860653 | Miranker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | data.world, Inc. (Austin, Texas) |
| ASSIGNEE(S) | data.world, Inc. (Austin, Texas) |
| INVENTOR(S) | Daniel Paul Miranker (Austin, Texas); Juan Federico Sequeda (Austin, Texas) |
| ABSTRACT | This invention is a system for integrating data sets organized in one organization type with data sets organized in a second organization type so that data queries submitted to be processed in the manner of the first organization type can be translated into queries usable by the data set in the second data organization type and the results returned to satisfy the first query. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/251408 |
| ART UNIT | 2157 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/25 (20190101) G06F 16/81 (20190101) G06F 16/86 (20190101) G06F 16/353 (20190101) G06F 16/8358 (20190101) G06F 16/8365 (20190101) G06F 16/90332 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860683 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Yi Xu (Endwell, New York); Zhongfei Mark Zhang (Vestal, New York) |
| ABSTRACT | The general problem of pattern change discovery between high-dimensional data sets is addressed by considering the notion of the principal angles between the subspaces is introduced to measure the subspace difference between two high-dimensional data sets. Current methods either mainly focus on magnitude change detection of low-dimensional data sets or are under supervised frameworks. Principal angles bear a property to isolate subspace change from the magnitude change. To address the challenge of directly computing the principal angles, matrix factorization is used to serve as a statistical framework and develop the principle of the dominant subspace mapping to transfer the principal angle based detection to a matrix factorization problem. Matrix factorization can be naturally embedded into the likelihood ratio test based on the linear models. The method may be unsupervised and addresses the statistical significance of the pattern changes between high-dimensional data sets. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/060743 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861668 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Liang Pan (West Lafayette, Indiana); Xianfan Xu (West Lafayette, Indiana) |
| ABSTRACT | A system for generating an electron beam array, comprising a light source, a first substrate having a plurality of plasmonic lenses mounted thereon, the plasmonic lenses configured to received light from the light source and produce an electron emission, and a plurality of electrostatic microlenses configured to focus the electron emissions into a beam for focusing on a wafer substrate. A light source modulator and digital micro mirror may be included which captures light from the light source and projects light beamlets on the plasmonic lenses. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/128441 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/10 (20130101) Original (OR) Class H01J 37/12 (20130101) H01J 37/073 (20130101) H01J 37/3174 (20130101) H01J 37/3177 (20130101) H01J 2201/342 (20130101) H01J 2237/062 (20130101) H01J 2237/202 (20130101) H01J 2237/0492 (20130101) H01J 2237/06333 (20130101) H01J 2237/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862692 | Shahrjerdi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Davood Shahrjerdi (New York, New York); Abdullah Alharbi (Brooklyn, New York) |
| ABSTRACT | An article of manufacture includes a substrate and a security primitive deposited on the substrate. The security primitive includes a transition metal dichalcogenide having a varying thickness. According to various embodiments, the transition metal dichalcogenide comprises a chalcogen atom (X) selected from the group consisting of S, Se, and Te and a transition metal (M) selected from the group consisting of Mo, W, Hf, and Zr. The security primitive is pixelated into a plurality of discrete regions having different luminescence. A security primitive key includes a first set of data values corresponding to a first set of coordinates of a first region and a second set of data values corresponding to a second set of coordinates of a second region. In some embodiments, the security primitive key is digitally captured through an optical reader and verified by querying a database. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 15/847460 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) B05D 5/061 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/681 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10857597 | Brice |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Craig A. Brice (Yorktown, Virginia) |
| ABSTRACT | Methods and devices are disclosed for creating a multiple alloy composite structure by forming a three-dimensional arrangement of a first alloy composition in which the three-dimensional arrangement has a substantially open and continuous porosity. The three-dimensional arrangement of the first alloy composition is infused with at least a second alloy composition, where the second alloy composition comprises a shape memory alloy. The three-dimensional arrangement is consolidated into a fully dense solid structure, and the original shape of the second alloy composition is set for reversible transformation. Strain is applied to the fully dense solid structure, which is treated with heat so that the shape memory alloy composition becomes memory activated to recover the original shape. An interwoven composite of the first alloy composition and the memory-activated second alloy composition is thereby formed in the multiple alloy composite structure. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707479 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/15 (20130101) B22F 3/15 (20130101) B22F 3/18 (20130101) B22F 3/18 (20130101) B22F 3/26 (20130101) B22F 3/125 (20130101) B22F 3/125 (20130101) B22F 3/1055 (20130101) B22F 3/1055 (20130101) B22F 7/02 (20130101) Original (OR) Class B22F 2003/247 (20130101) B22F 2003/248 (20130101) B22F 2003/248 (20130101) B22F 2003/248 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/12042 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858126 | Doggett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A., as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | William R. Doggett (Poquoson, Virginia); Timothy S. Roach (Virgina Beach, Virginia); Gerard D. Valle (Pearland, Texas); Molly M. Selig (League City, Texas); Winfred S. Kenner (Yorktown, Virginia); Thomas C. Jones (Newport News, Virginia); Judith J. Watson (Yorktown, Virginia); Lynn M. Bowman (Chesapeake, Virginia); Mary Jane E. O'Rourke (Seabrook, Texas); Bryan C. Yount (Sunnyvale, California); Alberto Makino (Standford, California); John T. Dorsey (Hampton, Virginia); Russell W. Smith (Newport News, Virginia); Clarence E. Stanfield (Hampton, Virginia); Jasen L. Raboin (League City, Texas) |
| ABSTRACT | A deformable closure mechanism for an aperture that may include an aperture seal that has a seal seat between an internal support structure and an external support structure. A barrier structure may be configured to resealably close the aperture, and have a central membrane and a barrier sealed that is inflatable in order to engage the barrier structure with the aperture seal. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/441318 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/12 (20130101) B64G 1/66 (20130101) Original (OR) Class B64G 2001/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858754 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Hyun Jung Kim (Poquson, Virginia); Sang Hyouk Choi (Poquoson, Virginia) |
| ABSTRACT | Some aspects relate to methods of forming an epitaxial layer. In some examples, the methods include ejecting atoms from a molten metal sputtering material onto a heated crystalline substrate and growing a single epitaxial layer on the substrate from the ejected atoms, where the atoms are ejected with sufficient energy that the grown epitaxial layer has at least a partial rhombohedral lattice, and wherein the crystalline substrate is heated to a temperature of about 600 degrees Celsius or less, or about 500 degrees or less. Other aspects relate to materials, such as a material including a single epitaxial layer on top of a crystalline substrate, the layer including one or more semiconductor materials and having at least a partial rhombohedral lattice, or a substantially rhombohedral lattice. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/358987 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/08 (20130101) Original (OR) Class C30B 23/066 (20130101) C30B 29/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/02433 (20130101) H01L 21/02532 (20130101) H01L 21/02609 (20130101) H01L 21/02631 (20130101) H01L 21/02658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859398 | Sweet |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Douglas Sweet (Campbell, California) |
| ABSTRACT | Systems, devices, methods, and techniques are described for automated air traffic management using multiple flight operation modes. In one example, a method includes receiving, by a computing device comprising one or more processors, data associated with one or more aircraft in flight in a controlled airspace. The method further includes selecting, by the computing device, based at least in part on the data associated with the one or more aircraft, a respective flight operation mode from among a plurality of flight operation modes for at least one respective aircraft among the one or more aircraft in flight. The method further includes outputting, by the computing device for transmission to the at least one respective aircraft, an indication of the respective flight operation mode selected for the at least one respective aircraft. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/344104 |
| ART UNIT | 3619 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/00 (20130101) Original (OR) Class Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0082 (20130101) G08G 5/0091 (20130101) Transmission H04B 7/18506 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859448 | Barnard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Casey A. Barnard (Gainesville, Florida); Jessica C. Meloy (Seattle, Washington); Mark Sheplak (Gainesville, Florida) |
| ABSTRACT | A sensor system comprising a Micro-Electro-Mechanical Systems (MEMS)-based capacitive floating element shear stress sensor, the associated packaging, and the interface circuitry required for operation as an instrumentation-grade sensing system is disclosed herein. One implementation of the interface circuitry is an analog synchronous modulation/demodulation scheme enabling time-resolved measurements of both mean and dynamic wall shear stress events, where a modulation section couples to the sensor for sensing wall shear stress at the surface of an object in a fluid and generates at least one bias signal from the sensor output signal. In response to the bias signal, a demodulation control circuit adjusts the phase of the bias signal and generates a demodulation control signal from the phase adjusted signal. Consequently, in response to the demodulation control signal, a demodulation section synchronizes the rectification of the sensor output signal, while the phase information is maintained. |
| FILED | Thursday, February 11, 2016 |
| APPL NO | 15/550466 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/007 (20130101) B81B 7/0064 (20130101) B81B 2207/012 (20130101) B81B 2207/096 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/144 (20130101) Original (OR) Class G01L 1/146 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/00 (20130101) G01N 11/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/48 (20130101) H01L 2224/45099 (20130101) H01L 2224/48227 (20130101) H01L 2224/48227 (20130101) H01L 2224/48465 (20130101) H01L 2224/48465 (20130101) H01L 2924/00 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/1433 (20130101) H01L 2924/1461 (20130101) H01L 2924/3025 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/183 (20130101) H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861256 | Colombano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | USA as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Silvano P. Colombano (Pacifica, California); Liljana Spirkovska (Sunnyvale, California); Paul H. Morris (Mountain View, California) |
| ABSTRACT | A system and method of warning and planning failure responses using an automated failure response system including, providing an electro-mechanical system having mechanical and electrical components and providing a failure response system for diagnosing failures of the components. The failure response system then determines effects of said failures on carrying out system activities using the failure response system, quantifies a severity for each failure diagnosed by the failure response system, and identifies repairs for each component failure. The failure response system also prioritizes each failure of a component based on severity and then recommends which repairs should be prioritized as most urgent to keep the electro-mechanical system operational based upon the severity of the associated failures and the effects of their corresponding failure. |
| FILED | Monday, August 29, 2016 |
| APPL NO | 15/249912 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/52 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0808 (20130101) Original (OR) Class G07C 5/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862189 | Romanofsky |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert R. Romanofsky (Hinckley, Ohio) |
| ABSTRACT | An apparatus that combines an antenna and telescope to minimize system mass without compromising performance of either the antenna or telescope. The apparatus includes a sub-reflector placed before a prime focus feed of a hybrid reflector system. The apparatus also includes a radio frequency (RF) reflector is rigidly attached to a body of a spacecraft and an optical section is attached to a vibration isolation platform. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 15/804374 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 17/061 (20130101) G02B 23/06 (20130101) G02B 23/16 (20130101) Antennas, i.e Radio Aerials H01Q 1/22 (20130101) Original (OR) Class H01Q 1/27 (20130101) H01Q 19/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10863370 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Friday, December 27, 2019 |
| APPL NO | 16/729226 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10856760 | Narayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); TOPERA, INC. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sanjiv M. Narayan (Palo Alto, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | A system for processing cardiac activation information associated with a complex rhythm disorder identifies a location of the heart rhythm disorder by determining activations within cardiac signals obtained at neighboring locations of the heart and arranging the activations to identify an activation trail. The activation trail may define a rotational pattern or radially emanating pattern corresponding to an approximate core of the heart rhythm disorder. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/649494 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0255 (20130101) A61B 5/0422 (20130101) A61B 5/0432 (20130101) A61B 5/0452 (20130101) Original (OR) Class A61B 5/0456 (20130101) A61B 5/0464 (20130101) A61B 5/0472 (20130101) A61B 5/726 (20130101) A61B 5/04011 (20130101) A61B 5/04012 (20130101) A61B 5/4857 (20130101) A61B 5/6852 (20130101) A61B 5/7221 (20130101) A61B 5/7264 (20130101) A61B 5/7278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10856800 | Woodward |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Steven H. Woodward (Palo Alto, California) |
| ABSTRACT | A portable polysomnography apparatus comprises a unitary flexible structured pillow that is embedded with accelerometers for data collection. The polysomnography apparatus is advantageously sized and shaped to cause the sleeping subject to properly orient the embedded accelerometers for optimal data collection while the subject is asleep. A portable polysomnography system comprises a structured pillow with embedded sensors that are in wireless communication with a companion data collection device that records data from the embedded sensors. In an alternative embodiment, a system may include a structured pillow with an internal pocket into which a single device including embedded sensors and data recording capabilities is inserted. |
| FILED | Friday, June 07, 2013 |
| APPL NO | 13/912405 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/002 (20130101) A61B 5/11 (20130101) A61B 5/70 (20130101) A61B 5/0476 (20130101) A61B 5/0488 (20130101) A61B 5/0496 (20130101) A61B 5/4806 (20130101) Original (OR) Class A61B 5/6887 (20130101) A61B 5/6892 (20130101) A61B 5/14542 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857174 | Ambady et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Prakash Ambady (Portland, Oregon); Jeffrey Wu (Portland, Oregon); Edward Neuwelt (Portland, Oregon) |
| ABSTRACT | Disclosed are morpholino oligonucleotides that can be used to silence expression of MGMT, pharmaceutical compositions that include said morpholino oligonucleotides, and methods of using said morpholino oligonucleotides in the treatment of cancer, particularly methods that involve the use of radiation to deliver said morpholino oligonucleotides. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522381 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/711 (20130101) Original (OR) Class A61K 31/4162 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857187 | Patel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Niketa A. Patel (Land O Lakes, Florida); Paula Cole Bickford (Ruskin, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Niketa A. Patel (Land O Lakes, Florida); Paula Cole Bickford (Ruskin, Florida) |
| ABSTRACT | Brain injury can be caused by trauma or may occur in stroke or neurodegenerative diseases. The disclosure relates to compositions that can include exosomes isolated from human adipose-derived stem cells (hASC) and methods where exosomes from hASC may be used alone or in combination with insulin for the treatment of brain injury. |
| FILED | Monday, June 18, 2018 |
| APPL NO | 16/011239 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/35 (20130101) Original (OR) Class A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 48/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857219 | Hildebrand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University Of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | William H. Hildebrand (Edmond, Oklahoma); Curtis McMurtrey (Oklahoma City, Oklahoma); David Lewinsohn (Portland, Oregon); Deborah Lewinsohn (Portland, Oregon); Melanie Harriff (Portland, Oregon) |
| ABSTRACT | Compositions that include one isolated, class I HLA-E trimolecular complex that includes a peptide ligand unique to M. tuberculosis-infected cells are disclosed. Isolated compositions that include the three components of the trimolecular complex and/or a polynucleotide encoding one or more of the three components are also disclosed. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671322 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/605 (20130101) Peptides C07K 14/35 (20130101) C07K 14/70539 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10857265 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | James Chang (Stanford, California); Hung Pham (Milpitas, California); Colin Woon (Chicago, Illinois); Simon Farnebo (Palo Alto, California); Anais Legrand (Palo Alto, California) |
| ABSTRACT | The invention provides an injectable composition and method for the minimally invasive, in-situ repair and regeneration of an injured ligament or tendon in a mammalian subject. The composition is also useful for the delivery of growth factors, therapeutic agents and cells into the area of tendon or ligament injury. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/837300 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/12 (20130101) A61K 35/16 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/386 (20130101) A61L 27/3633 (20130101) A61L 27/3662 (20130101) A61L 27/3687 (20130101) A61L 27/3804 (20130101) A61L 27/3834 (20130101) A61L 2300/45 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/402 (20130101) A61L 2300/406 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/10 (20130101) A61L 2430/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10858633 | Puckette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Puckette (Waterford, Connecticut); Max V. Rasmussen (Guilford, Connecticut) |
| ABSTRACT | This application is directed generally to foot-and-mouth disease virus (FMDV) 3C proteases that have been modified by mutating a polynucleotide sequence coding for the FMDV 3C protease. The modified FMDV proteases exhibit proteolytic activity on FMDV P1 precursor protein and exhibit a reduction in one or more toxic or inhibitory properties associated with an unmodified FMDV 3C protease on a host cell used to recombinantly produce it. Vectors carrying polynucleotides encoding modified FMDV 3C protease sequences can induce production of FMDV virus-like particles in a host cell when expressed in the host cell. The modified FMDV 3C proteases can generally be used to produce immunogenic FMDV preparations capable of inducing an immune response against FMDV. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/368146 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/135 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1009 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/506 (20130101) C12N 2770/32122 (20130101) C12N 2770/32123 (20130101) C12N 2770/32134 (20130101) C12N 2770/32151 (20130101) Enzymes C12Y 304/22028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6854 (20130101) G01N 33/56972 (20130101) G01N 33/56983 (20130101) G01N 2333/09 (20130101) G01N 2333/9513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10858634 | Puckette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Puckette (Waterford, Connecticut); Max V. Rasmussen (Guilford, Connecticut) |
| ABSTRACT | This application is directed generally to foot-and-mouth disease virus (FMDV) 3C proteases that have been modified by mutating a polynucleotide sequence coding for the FMDV 3C protease. The modified FMDV proteases exhibit proteolytic activity on FMDV P1 precursor protein and exhibit a reduction in one or more toxic or inhibitory properties associated with an unmodified FMDV 3C protease on a host cell used to recombinantly produce it. Vectors carrying polynucleotides encoding modified FMDV 3C protease sequences can induce production of FMDV virus-like particles in a host cell when expressed in the host cell. The modified FMDV 3C proteases can generally be used to produce immunogenic FMDV preparations capable of inducing an immune response against FMDV. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/368327 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/135 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1009 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/506 (20130101) C12N 2770/32122 (20130101) C12N 2770/32123 (20130101) C12N 2770/32134 (20130101) C12N 2770/32151 (20130101) Enzymes C12Y 304/22028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6854 (20130101) G01N 33/56972 (20130101) G01N 33/56983 (20130101) G01N 2333/09 (20130101) G01N 2333/9513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859517 | Hesselink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Lambertus Hesselink (Atherton, California); Max Yuen (San Francisco, California); Yao-Te Cheng (New Taipei, Taiwan); Yuzuru Takashima (Cupertino, California) |
| ABSTRACT | Single X-ray grating differential phase contrast (DPC) X-ray imaging is provided by replacing the conventional X-ray source with a photo-emitter X-ray source array (PeXSA), and by replacing the conventional X-ray detector with a photonic-channeled X-ray detector array (PcXDA). These substitutions allow for the elimination of the G0 and G2 amplitude X-ray gratings used in conventional DPC X-ray imaging. Equivalent spatial patterns are formed optically in the PeXSA and the PcXDA. The result is DPC imaging that only has a single X-ray grating (i.e., the G1 X-ray phase grating). |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/640092 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/483 (20130101) A61B 6/484 (20130101) A61B 6/4241 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/041 (20180201) G01N 23/20075 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) G01T 1/2018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10862908 | Nogin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Aleksey Nogin (Fresno, California); Joshua D. Lampkins (Gardena, California) |
| ABSTRACT | The system is directed to a plurality of nodes in a network and a process by which the nodes reach a consensus ordering of broadcast messages. For example, one or more nodes proceed by agreeing on an order of two or more broadcast message derived events A and B. If a node sees event A longer than a time period (T6) before seeing event B, then the node outputs “A consensus-before B” as a consensus broadcast ordering. If the node sees the event A and not the event B after waiting at least T6, then the node outputs “A consensus-before B” as a consensus broadcast ordering. However, if the node sees both events A and event B within T6, then the node broadcasts a request for a vote on message ordering, executes a consensus broadcast reception protocol for the votes, and makes an ordering decision based on the votes received. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450170 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/783 (20130101) H04L 47/806 (20130101) H04L 63/0421 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) Wireless Communication Networks H04W 12/1202 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 10856815 | Pereira et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| INVENTOR(S) | Francisco Pereira (Jersey City, New Jersey); Bin Lou (West Windsor, New Jersey); Angeliki Lazaridou (Artemida, Greece) |
| ABSTRACT | By way of introduction, the present embodiments described below include apparatuses and methods for generating natural language representations of mental content from functional brain images. Given functional imaging data acquired while a subject reads a text passage, a reconstruction of the text passage is produced. Linguistic semantic vector representations are assigned (1301) to words, phrases or sentences to be used as training stimuli. Basis learning is performed (1305), using brain imaging data acquired (1303) when a subject is exposed to the training stimuli and the corresponding semantic vectors for training stimuli, to learn an image basis directly. Semantic vector decoding (1309) is performed with functional brain imaging data for test stimuli and using the image basis to generate a semantic vector representing the test imaging stimuli. Text generation (1311) is then performed using the decoded semantic vector representing the test imaging stimuli. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/752276 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) A61B 5/04842 (20130101) A61B 5/7267 (20130101) Original (OR) Class Electric Digital Data Processing G06F 40/30 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860837 | Ranjan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Rajeev Ranjan (College Park, Maryland); Vishal M. Patel (Silver Spring, Maryland); Ramalingam Chellappa (Potomac, Maryland); Carlos D. Castillo (Silver Spring, Maryland) |
| ABSTRACT | Various image processing may benefit from the application deep convolutional neural networks. For example, a deep multi-task learning framework may assist face detection, for example when combined with landmark localization, pose estimation, and gender recognition. An apparatus can include a first module of at least three modules configured to generate class independent region proposals to provide a region. The apparatus can also include a second module of the at least three modules configured to classify the region as face or non-face using a multi-task analysis. The apparatus can further include a third module configured to perform post-processing on the classified region. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/746237 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/036 (20130101) G06K 9/00248 (20130101) G06K 9/00281 (20130101) Original (OR) Class G06K 9/4628 (20130101) G06K 9/6267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10860916 | Lal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Serhan Ardanuc (Ithaca, New York); Jason T. Hoople (Ithaca, New York); Justin C. Kuo (Ithaca, New York) |
| ABSTRACT | Techniques, systems, and devices are described for implementing for implementing computation devices and artificial neurons based on nanoelectromechanical (NEMS) systems. In one aspect, a nanoelectromechanical system (NEMS) based computing element includes: a substrate; two electrodes configured as a first beam structure and a second beam structure positioned in close proximity with each other without contact, wherein the first beam structure is fixed to the substrate and the second beam structure is attached to the substrate while being free to bend under electrostatic force. The first beam structure is kept at a constant voltage while the other voltage varies based on an input signal applied to the NEMS based computing element. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/880261 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 2201/018 (20130101) B81B 2201/0214 (20130101) B81B 2201/0285 (20130101) B81B 2203/04 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/521 (20130101) G01S 7/52079 (20130101) G01S 15/02 (20130101) G01S 15/8925 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0002 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/0635 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 1/0094 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10857008 | Haque et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Impulse Technology LLC (State College, Pennsylvania) |
| ASSIGNEE(S) | Impulse Technology LLC (State College, Pennsylvania) |
| INVENTOR(S) | Md Amanul Haque (State College, Pennsylvania); Vamsidhar Reddy Rajula (State College, Pennsylvania); Mst (Kamrun) Kamrunnahar (State College, Pennsylvania) |
| ABSTRACT | A self-adjusting adapter for a prosthetic leg having a foot and a leg socket has a low stiffness spring having a central opening, a high stiffness spring that has a central opening and is adjacent the low stiffness spring, a shaft or a bolt passing through the central opening in the low stiffness spring and the central opening in the high stiffness spring and a spring stiffener configured and positioned to restrain movement of the high stiffness spring relative to the low stiffness spring in a direction parallel to the low-stiffness spring. A connector for attaching the adapter to a leg socket is connected to the bolt or shaft and is capable of pivoting about an axis through the bolt or shaft. The adapter can be used an add-on component for existing prosthetic legs, or it can be integrated with foot design for the ankle-foot product category. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/536935 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 2002/503 (20130101) A61F 2002/5078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10859700 | Ngai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Z-SENZ LLC (Oak Shade Rd, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darryl Ngai (Bathesda, Maryland); Christopher Brown (Gaithersburg, Maryland) |
| ABSTRACT | Certain exemplary embodiments can provide an instrument comprising a signal generator. The signal generator is constructed to generate a temporally distinct profile of LIDAR pulses and a reference signal. The instrument comprises a light source coupled to the signal generator. The light source constructed to receive the temporally distinct profile of LIDAR pulses and output corresponding light pulses with temporal spacing substantially equal to those of temporally distinct profile. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 15/656901 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/497 (20130101) G01S 17/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10858704 | Lambert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Kris Lambert (Urbana, Illinois); Sadia Bekal (Urbana, Illinois) |
| ABSTRACT | Phytoparasitic nematodes that are able to infect and reproduce on plants that are considered resistant are referred to as virulent. The mechanism(s) that virulent nematodes employ to evade or suppress host plant defenses are not well understood. Described herein is the discovery of three single nucleotide polymorphisms (SNPs) that reproducibly show allele imbalances between soybean cyst nematode (SCN) grown on resistant and susceptible soybean (Heterodera glycines) plants. Two candidate SCN virulence genes, biotin synthase (HgBioB) and a bacterial-like protein containing a putative SNARE domain (HgSLP-1), were tightly linked to the SNPs. Methods, kits, and compositions are provided for using these discoveries to detect and quantify SCN virulence in field samples. Also provided are methods for planting fields in accordance with the results of detecting (or not detecting) virulent SCN in the fields. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939854 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10858256 | Gui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California); Jason K. Streit (Gaithersburg, Maryland); Angela R. Hight Walker (Gaithersburg, Maryland); Ming Zheng (Gaithersburg, Maryland) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California); Government of the United States of America, as Represented by the Secretary of Commerce, National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | Hui Gui (Los Angeles, California); Jason K. Streit (Gaithersburg, Maryland); Angela R. Hight Walker (Gaithersburg, Maryland); Chongwu Zhou (San Marino, California); Ming Zheng (Rockville, Maryland) |
| ABSTRACT | A method of separating and extracting carbon nanotubes, the method includes introducing the carbon nanotubes into a two-phase system that includes a first component and a second component, the first component being different from the second component. The method includes introducing a chemical agent into the two-phase system, mixing the chemical agent and the carbon nanotubes in the two-phase system, removing the first component to extract a first portion of the carbon nanotubes contained in the first component after the mixing, replenishing the two-phase system with fresh first component, and extracting a second portion of the carbon nanotubes contained in the fresh first component. A bandgap of the carbon nanotubes in the first portion is different from the bandgap of the carbon nanotubes in the second portion. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/545659 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/17 (20170801) C01B 32/172 (20170801) Original (OR) Class C01B 2202/02 (20130101) C01B 2202/22 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10857596 | Mittendorf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Don Mittendorf (Mesa, Arizona); Jason Smoke (Phoenix, Arizona); Brent Ludwig (Scottsdale, Arizona) |
| ABSTRACT | A method of producing an abrasive tip for a turbine blade includes producing or obtaining a metal powder that is mixed with an abrasive ceramic powder and producing or obtaining a metallic mold that is in the shape of an airfoil. The metallic mold includes a hollow interior portion. The method further includes sealing the metal and ceramic powder mixture within the hollow interior portion of the metallic mold under vacuum and subjecting the sealed mold to a hot isostatic pressing process. The hot isostatic pressing process compacts and binds the metal and ceramic powder mixture together into a solid article in the shape of the airfoil. Still further, the method includes slicing the solid article into a plurality of airfoil-shaped slices and bonding one slice of the plurality of airfoil-shaped slices to a tip portion of a turbine blade. |
| FILED | Tuesday, September 11, 2018 |
| APPL NO | 16/127383 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/15 (20130101) B22F 3/156 (20130101) B22F 5/04 (20130101) Original (OR) Class Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/04 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 2043/106 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/23 (20130101) F05D 2230/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10858190 | Arlt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Hans Arlt (Vienna, Virginia); Christopher R. Simpson (Olney, Maryland) |
| ABSTRACT | A pulley assembly for an automative machine and methods for the same are disclosed. The pulley assembly may include a monolithic body, an actuation assembly, and a pulley. The body may define a recess extending from a first end surface toward a second end surface thereof. The recess may separate an upper portion from a lower portion of the body. The body may define a bore extending through the upper and lower portions of the body. The bore may be threaded along a length thereof. The actuation assembly may include a mechanical biasing element having a threaded portion. The mechanical biasing element may be disposed in the bore such that the threaded portion thereof is threadably coupled with the threaded portion of the bore. The pulley may be rotatably coupled with the upper portion of the body such that the pully moves when the upper portion is actuated. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 16/749666 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 15/64 (20130101) Original (OR) Class B65G 23/06 (20130101) B65G 39/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10859664 | Bowden |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | James M. Bowden (Forney, Texas) |
| ABSTRACT | A direction finding (DF) system and technique using a switched network architecture to couple a first plurality of antenna elements to a second, fewer, plurality of channels of an RF receiver. The RF receiver provides signals to a DF processor which combines data sampled at phase centers of the plurality of array elements. Such combined data samples may be used to estimate a direction of a received signal. The antenna elements may be configured into subarrays and a switch network couples different groups of subarrays to the RF receiver channels during different dwell times. Data collected during each dwell may be used to generate a spatial sample covariance matrix (SCM) and multiple spatial SCMs may be combined to provide aggregate covariance matrix values. A DF processor uses values from the aggregate covariance matrix to provide an output signal indicative of the direction of a received signal. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267824 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/14 (20130101) G01S 3/043 (20130101) Original (OR) Class G01S 3/48 (20130101) G01S 3/74 (20130101) G01S 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10861892 | McGrath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Robert Daniel McGrath (Lexington, Massachusetts); Stephen P. Tobin (Carlisle, Massachusetts) |
| ABSTRACT | A system for low light level image sensing is provided having: A photodiode; a transfer gate disposed in a center of the photodiode; an active gate disposed surrounded by the transfer gate; a plurality of microlenses, each microlens being disposed over a portion of the photodiode and directing light away from the transfer gate towards the photodiode. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/198298 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14607 (20130101) H01L 27/14614 (20130101) H01L 27/14627 (20130101) Original (OR) Class H01L 27/14643 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 08, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201208.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page