FedInvent™ Patents
Patent Details for Tuesday, December 15, 2020
This page was updated on Monday, March 27, 2023 at 06:15 AM GMT
Department of Health and Human Services (HHS)
| US 10863940 | Gazzaley |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Adam Gazzaley (San Francisco, California) |
| ABSTRACT | Provided are methods of enhancing the performance of a subject on a cognitive task by improved self-regulation of internal distraction. The methods include presenting a computer-based cognitive training program to a subject, where performance of the subject on the cognitive task is enhanced by the cognitive training program. Computer readable media and devices useful for practicing the methods of the present disclosure are also provided. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 15/507922 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/168 (20130101) Original (OR) Class A61B 5/0482 (20130101) A61B 5/486 (20130101) A61B 5/04842 (20130101) A61B 5/04845 (20130101) A61B 5/6803 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/06 (20130101) G09B 7/02 (20130101) G09B 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10863968 | Rosado-Mendez et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ivan Miguel Rosado-Mendez (Madison, Wisconsin); Timothy Jon Hall (Madison, Wisconsin) |
| ABSTRACT | An ultrasound machine for generating push-pulses to excite shear wave stimulation employs separated angled beams that converge at the target region to generate the push-pulses. In one embodiment, the beams are modulated by a set of apodization functions to reduce side lobes caused by the narrowing of the apertures of the beam as well as transducer heating by reducing the average energy deposited in each transducer element. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/501207 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/485 (20130101) A61B 8/4494 (20130101) Original (OR) Class A61B 8/5207 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 2201/20 (20130101) B06B 2201/40 (20130101) B06B 2201/55 (20130101) B06B 2201/76 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52022 (20130101) G01S 7/52042 (20130101) G01S 7/52047 (20130101) G01S 7/52071 (20130101) G01S 15/8915 (20130101) G01S 15/8927 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/346 (20130101) G10K 11/348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864096 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Monarch Biosciences, Inc. (Los Angeles, California) |
| ASSIGNEE(S) | MONARCH BIOSCIENCES, INC. (Los Angeles, California) |
| INVENTOR(S) | Alfred David Johnson (San Leandro, California); Colin Kealey (Los Angeles, California) |
| ABSTRACT | A method of manufacturing three-dimensional thin-film nitinol (NiTi) devices includes: depositing multiple layers of nitinol and sacrificial material on a substrate. A three-dimensional thin-film nitinol device may include a first layer of nitinol and a second layer of nitinol bonded to the first layer at an area masked and not covered by the sacrificial material during deposition of the second layer. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298758 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) A61F 2/86 (20130101) A61F 2/90 (20130101) Original (OR) Class A61F 2/844 (20130101) A61F 2002/068 (20130101) A61F 2002/823 (20130101) A61F 2210/0014 (20130101) A61F 2210/0076 (20130101) A61F 2230/0017 (20130101) A61F 2230/0069 (20130101) A61F 2240/001 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/088 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00476 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/34 (20130101) C23C 14/042 (20130101) C23C 14/165 (20130101) C23C 14/5846 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864153 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | X. Z. Shawn Xu (Ann Arbor, Michigan); Jianfeng Liu (Wuhan, China PRC) |
| ABSTRACT | The present disclosure relates to compositions capable of absorbing UVA and UVB light. In particle, the present disclosure relates to UV screening compositions comprising at least a portion of LITE-1 polypeptides which are capable of absorbing UV light (e.g., UV-A and/or UV-B light). |
| FILED | Monday, November 13, 2017 |
| APPL NO | 16/349448 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 38/1767 (20130101) A61K 2800/10 (20130101) A61K 2800/86 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864162 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Icahn School of Medicine at Mount Sinai (New York, New York); New York University (New York, New York) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Cambridge, Massachusetts); ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | YongTae Kim (Suwanee, Georgia); Zahi Fayad (Larchmont, New York); Willem J. Mulder (New York, New York); Edward Fisher (Scarsdale, New York); Francois Fay (New York, New York); Omid C. Farokhzad (Waban, Massachusetts); Robert Langer (Newton, Massachusetts) |
| ABSTRACT | Methods for making particles, such as nanoparticles, devices useful in the methods, and particles made by the method are described herein. The methods involves the use of microfluidic device, such that upon mixing solutions of the materials to form the particles (or a solution of the material or materials to form the particles and a non-solvent for the material or materials) at least two symmetrical microvortices are formed simultaneously. The method can be used to prepare polymeric or non-polymeric particles and hybrid particles, such as lipid-polymer hybrid particles, as well as such particles containing one or more agents associated with the particles. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 15/617557 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/145 (20130101) A61K 9/146 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 9/5176 (20130101) A61K 9/5192 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864170 | Fahmy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Jung Seok Lee (New Haven, Connecticut); Dongin Kim (Glastonbury, Connecticut) |
| ABSTRACT | Pharmaceutical composition containing poly(bile) acid (PBA) polymers for oral delivery of agent(s) show enhanced uptake by the pancreas, liver, and colon. These nanoparticles show significant retention in the pancreas and colon and are therefore useful for selective delivery. The examples demonstrate efficacy of oral administration of insulin to treat diabetes, and oral induction of tolerance by administration of insulin or ovalbumin in combination with rapamycin. Diabetic animals treated with the insulin or insulin with rapamycin showed normalization of blood glucose levels. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/757608 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 31/436 (20130101) A61K 38/28 (20130101) A61K 45/00 (20130101) A61K 47/6935 (20170801) A61K 49/1824 (20130101) A61K 51/1244 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 1/18 (20180101) A61P 3/10 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864217 | Pache et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California); Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California); SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| INVENTOR(S) | Lars Pache (La Jolla, California); Sumit K. Chanda (La Jolla, California); Mitchell Dennis Vamos (La Jolla, California); Nicholas David Peter Cosford (La Jolla, California); Peter Teriete (La Jolla, California); John Marlett (La Jolla, California); Arturo Diaz (La Jolla, California); John A. T. Young (La Jolla, California) |
| ABSTRACT | Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV). |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/421966 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/20 (20130101) A61K 31/20 (20130101) A61K 31/27 (20130101) A61K 31/27 (20130101) A61K 31/55 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/551 (20130101) A61K 31/553 (20130101) Original (OR) Class A61K 31/553 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4045 (20130101) A61K 31/4045 (20130101) A61K 31/4406 (20130101) A61K 31/4406 (20130101) A61K 31/5365 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864219 | Popov et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Alexey Popov (Waltham, Massachusetts); Elizabeth M. Enlow (Waltham, Massachusetts); Hongming Chen (Belmont, Massachusetts); James Bourassa (Somerville, Massachusetts) |
| ABSTRACT | Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/221253 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0048 (20130101) A61K 9/5031 (20130101) A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 31/56 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864222 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yu Chen (Tampa, Florida); Orville Antonio Pemberton (Tampa, Florida); Adam Renslo (Oakland, California); Priyadarshini Jaishankar (Newark, California) |
| ABSTRACT | Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat bacterial infections. Also provided herein are methods of making and using the heterocyclic compounds and pharmaceutical formulations. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/721090 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) A61K 31/665 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/60 (20130101) C07F 9/6561 (20130101) C07F 9/65522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864229 | Kevil et al. |
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| FUNDED BY |
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| APPLICANT(S) | The UAB Research Foundation (Birmingham, Alabama); The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana) |
| INVENTOR(S) | Christopher Kevil (Shreveport, Louisiana); David Lefer (Decatur, Georgia); Rakesh Patel (Hoover, Alabama) |
| ABSTRACT | Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue. The subject can be diagnosed as having a medical condition that results in persistent or recurring restriction of blood supply to a tissue, for example, peripheral artery disease, diabetes, atherosclerotic cardiovascular disease or defective wound healing. The methods can include the step of identifying a suitable subject. |
| FILED | Monday, April 10, 2017 |
| APPL NO | 15/483187 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) A61K 33/06 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864244 | Srinivasan et al. |
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| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| INVENTOR(S) | Mythily Srinivasan (Greenwood, Indiana); Debomoy Lahiri (Brownsburg, Indiana) |
| ABSTRACT | The present disclosure provides pharmaceutical compositions comprising rationally designed peptide analogs of the p65-TAD binding region of GILZ to selectively sequester activated p65. Structural and functional analyses suggest that select GILZ analog (GA) bind p65-TAD with optimum affinity, exhibit an estimated half minimal lethal dose comparable to known peptide drugs and suppress Aβ1-42 induced cytotoxicity. Furthermore, the present disclosure provides uses and methods of using the pharmaceutical compositions, and uses and methods of using pharmaceutical formulations comprising the pharmaceutical compositions, for the treatment of neurodegenerative diseases such as Alzheimer's Disease, Parkinson's Disease, multiple sclerosis, and amyotrophic lateral sclerosis (ALS). |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/108605 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864251 | Rapraeger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Alan C. Rapraeger (Madison, Wisconsin); DeannaLee M. Beauvais (Madison, Wisconsin) |
| ABSTRACT | The present invention provides a peptide derived from the extracellular domain of syndecan-1 that inhibits angiogenesis. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/251217 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/705 (20130101) C07K 14/4725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864252 | Morgan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of Americans represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard A. Morgan (Columbia, Maryland); Nachimuthu Chinnasamy (North Potomac, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for synovial sarcoma X Breakpoint (SSX)-2. The invention further provides related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells. Further provided by the invention are antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are further provided by the invention. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/173701 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/177 (20130101) A61K 38/1774 (20130101) Original (OR) Class A61K 39/39558 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) C07K 16/2809 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864256 | Dubal |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dena Dubal (Oakland, California) |
| ABSTRACT | Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 16/751108 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/47 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Enzymes C12Y 302/01031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864258 | Bzik et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | David J. Bzik (Grantham, New Hampshire); Barbara A. Fox (Grantham, New Hampshire); Kiah L. Sanders (West Lebanon, New Hampshire) |
| ABSTRACT | Attenuated Toxoplasma gondii mutants and methods using the same as vaccines in the prevention or treatment pancreatic cancer are provided. |
| FILED | Tuesday, April 15, 2014 |
| APPL NO | 14/787488 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/002 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/57 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/585 (20130101) A61K 2039/852 (20180801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 9/001 (20130101) C12N 9/86 (20130101) C12N 9/88 (20130101) C12N 9/93 (20130101) C12N 9/1018 (20130101) C12N 9/1077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864264 | Dormitzer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Seqirus UK Limited (Berkshire, United Kingdom); Synthetic Genomics, Inc. (La Jolla, California) |
| ASSIGNEE(S) | Seqirus UK Limited (Maidenhead, United Kingdom); Synthetic Genomics, Inc. (La Jolla, California) |
| INVENTOR(S) | Philip Dormitzer (Cambridge, Massachusetts); Peter Mason (Cambridge, Massachusetts); Pirada Suphaphiphat (Cambridge, Massachusetts); Raul Gomila (Cambridge, Massachusetts) |
| ABSTRACT | New influenza donor strains for the production of reassortant influenza B viruses are provided. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657082 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16134 (20130101) C12N 2760/16234 (20130101) C12N 2760/16251 (20130101) C12N 2760/16252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864266 | Silhavy et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Thomas J. Silhavy (Belle Mead, New Jersey); Marcin Grabowicz (Princeton, New Jersey); Daniel Kahne (Brookline, Massachusetts); Matthew Lebar (Mandeville, Louisiana); Dorothee Andres (Potsdam, Germany) |
| ABSTRACT | The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/690739 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/55516 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) A61K 2039/55594 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/06 (20130101) C07H 15/04 (20130101) Peptides C07K 4/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/93 (20130101) C12N 15/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864270 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ratneshwar Lal (La Jolla, California); Preston B. Landon (San Diego, California); Alexander Mo (La Jolla, California) |
| ABSTRACT | Methods, systems, and devices are disclosed for fabricating and implementing nanoscale and microscale structured carriers to provide guided, targeted, and on-demand delivery of molecules and biochemical substances for a variety of applications including diagnosis and/or treatment (theranostics) of diseases in humans and animals. In some aspects, a nanostructure carrier can be synthesized in the form of a nanobowl, which may include an actuatable capping particle that can be opened (and in some implementations, closed) on demand. In some aspects, a nanostructure carrier can be synthesized in the form of a hollow porous nanoparticle with a functionalized interior and/or exterior to attach payload substances and substances for magnetically guided delivery and controlled release of substance payloads. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/111090 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0009 (20130101) A61K 9/5115 (20130101) A61K 9/5138 (20130101) A61K 9/5192 (20130101) A61K 38/05 (20130101) A61K 41/00 (20130101) Original (OR) Class A61K 41/0028 (20130101) A61K 47/6923 (20170801) A61K 47/6925 (20170801) A61K 47/6941 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864271 | Khan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Atif Jalees Khan (Bridgewater, New Jersey); Suzie Chen (Highland Park, New Jersey); James S. Goydos (New Brunswick, New Jersey); Bruce G. Haffty (New Brunswick, New Jersey) |
| ABSTRACT | Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents. |
| FILED | Friday, February 15, 2013 |
| APPL NO | 13/768544 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0038 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864282 | Tyavanagimatt et al. |
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| FUNDED BY |
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| APPLICANT(S) | SIGA TECHNOLOGIES, INC. (Corvallis, Oregon) |
| ASSIGNEE(S) | Siga Technologies Inc. (Corvallis, Oregon) |
| INVENTOR(S) | Shanthakumar R. Tyavanagimatt (Corvallis, Oregon); Melialani A. C. L. S. Anderson (Corvallis, Oregon); William Weimers (Corvallis, Oregon); Gopi Krishna Kasi (Lynnwood, Washington); N K Peter Samuel (Corvallis, Oregon); Tove C. Bolken (Keizer, Oregon); Dennis E. Hruby (Albany, Oregon) |
| ABSTRACT | The present invention provides for a novel liquid formulation for solubilizing poorly soluble ST-246 in cyclodextrins and a novel process of making the formulation. |
| FILED | Thursday, January 02, 2020 |
| APPL NO | 16/732509 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 31/715 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 31/4035 (20130101) A61K 31/4035 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/40 (20130101) A61K 47/6951 (20170801) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864285 | Chiorini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | John A. Chiorini (Dayton, Maryland); Hongen Yin (Bethesda, Maryland) |
| ABSTRACT | The finding that patients with Sjögren's syndrome exhibit a statistically significant increase in expression of BMP6 in the salivary gland relative to healthy control subjects is described. Also described is the finding that overexpression of BMP6 in the salivary glands of mice results in an increase in electrical potential across the salivary gland. Thus, methods of diagnosing a subject as having Sjögren's syndrome, or at risk for developing Sjögren's syndrome, by measuring the level of BMP6 expression in a salivary gland of a subject, measuring electrical potential in a salivary gland of a subject, or both, are disclosed. Also described are methods of treating a subject with Sjögren's syndrome by administering an agent that inhibits expression of BMP6 expression or activity. Further disclosed is the use of XIST and MECP2 as diagnostic and therapeutic targets for male Sjögren's syndrome patients. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 15/798969 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 38/177 (20130101) A61K 38/179 (20130101) A61K 49/0004 (20130101) Original (OR) Class Peptides C07K 16/22 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1136 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/6872 (20130101) G01N 33/6893 (20130101) G01N 2333/51 (20130101) G01N 2333/4704 (20130101) G01N 2800/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864299 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Siran Wang (Medford, Massachusetts); Rachel Gomes (Medford, Massachusetts); Chiara Ghezzi (Medford, Massachusetts); Dana Cairns (Medford, Massachusetts) |
| ABSTRACT | In some embodiments, the present invention provides tissue compositions including a first silk scaffold comprising a plurality of epithelial cells, a second silk scaffold comprising a plurality of stromal cells, and a plurality of neurons. In some embodiments, provided compositions can function as physiologically relevant corneal model systems for, inter alia, testing of therapeutics for corneal disease and/or injury and production of functional corneal tissue (e.g., for transplant, etc). The present invention also provides methods for making and using provided compositions. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 16/096851 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/56 (20130101) A61L 27/383 (20130101) A61L 27/3604 (20130101) Original (OR) Class A61L 27/3813 (20130101) A61L 27/3891 (20130101) A61L 2430/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 5/0621 (20130101) C12N 5/0697 (20130101) C12N 2500/38 (20130101) C12N 2501/11 (20130101) C12N 2501/12 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/117 (20130101) C12N 2502/081 (20130101) C12N 2502/083 (20130101) C12N 2502/085 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) C12N 2535/00 (20130101) C12N 2535/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864303 | Bettinger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher J. Bettinger (Palo Alto, California); Joost P. Bruggeman (Schorl, Netherlands); Lino da Silva Ferreira (Coimbra, Portugal); Jeffrey M. Karp (Brookline, Massachusetts); Robert S. Langer (Newton, Massachusetts); Christiaan Nijst (Amsterdam, Netherlands); Andreas Zumbuehl (Nyon, Switzerland); Jason Burdick (Philadelphia, Pennsylvania); Sonia J. Kim (West Nyack, New York) |
| ABSTRACT | The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206937 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/48 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/58 (20130101) A61L 31/06 (20130101) Original (OR) Class A61L 31/148 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/6854 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/246 (20130101) C08J 2367/00 (20130101) C08J 2367/07 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) C08L 67/07 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864373 | Bhadra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Niloy Bhadra (Cleveland, Ohio); Narendra Bhadra (Cleveland, Ohio); Kevin L. Kilgore (Cleveland, Ohio); Scott Lempka (Cleveland, Ohio); Jesse Wainright (Cleveland, Ohio); Tina Vrabec (Cleveland, Ohio); Manfred Franke (Cleveland, Ohio) |
| ABSTRACT | One aspect of the present disclosure is a system including a waveform generator, a controller, and an electrical contact. The waveform generator is for generating an electrical nerve conduction block (ENCB). The controller is coupled with the waveform generator. The controller is configured to receive an input comprising at least one parameter to adjust the ENCB. The electrical contact is coupled with the wave-form generator. The electrical contact is configured to be placed into contact with a nerve. The electrical contact comprises a high charge capacity material that prevents formation of damaging electro-chemical products at a charge delivered by the ENCB. The electrical contact is configured to deliver the ENCB to the nerve to block transmission of a signal related to a pain through the nerve. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/060979 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/06 (20130101) A61N 1/20 (20130101) A61N 1/0551 (20130101) A61N 1/36021 (20130101) A61N 1/36057 (20130101) A61N 1/36071 (20130101) Original (OR) Class A61N 1/36103 (20130101) A61N 1/36125 (20130101) A61N 1/36171 (20130101) A61N 1/36175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865128 | Ball |
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| FUNDED BY |
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| APPLICANT(S) | OXYTEC LLC (Newton, Massachusetts) |
| ASSIGNEE(S) | OXYTEC LLC (Newton, Massachusetts) |
| INVENTOR(S) | Raymond G. Ball (Newton, Massachusetts) |
| ABSTRACT | Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/269033 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) B09C 2101/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/70 (20130101) C02F 1/78 (20130101) C02F 1/722 (20130101) Original (OR) Class C02F 1/725 (20130101) C02F 1/727 (20130101) C02F 2101/34 (20130101) C02F 2101/36 (20130101) C02F 2101/305 (20130101) C02F 2101/306 (20130101) C02F 2101/322 (20130101) C02F 2101/327 (20130101) C02F 2101/363 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865181 | Roy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Sudeshna Roy (Lawrence, Kansas); Paolo Bernardi (Padua, Italy); Michael Forte (Portland, Oregon); Frank Schoenen (Lawrence, Kansas); Justina Sileikyte (Padua, Italy) |
| ABSTRACT | The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof. |
| FILED | Wednesday, November 04, 2015 |
| APPL NO | 15/524595 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/415 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 25/00 (20180101) Acyclic or Carbocyclic Compounds C07C 235/38 (20130101) C07C 235/42 (20130101) Original (OR) Class C07C 235/56 (20130101) Heterocyclic Compounds C07D 203/04 (20130101) C07D 211/14 (20130101) C07D 231/14 (20130101) C07D 261/18 (20130101) C07D 295/135 (20130101) C07D 295/185 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865196 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee); ONCTERNAL THERAPEUTICS, INC (San Diego, California) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); ONCTERNAL THERAPEUTICS, INC. (San Diego, California) |
| INVENTOR(S) | Duane D. Miller (Collierville, Tennessee); Jianjun Chen (Knoxville, Tennessee); James T. Dalton (Ann Arbor, Michigan); Chien-Ming Li (Fremont, California); Sunjoo Ahn (Yuseong-gu Daejeon, South Korea); Wei Li (Germantown, Tennessee) |
| ABSTRACT | The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872199 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/421 (20130101) A61K 31/426 (20130101) A61K 31/4178 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 233/02 (20130101) C07D 233/22 (20130101) C07D 233/54 (20130101) C07D 263/06 (20130101) C07D 263/14 (20130101) C07D 263/32 (20130101) C07D 277/04 (20130101) C07D 277/24 (20130101) C07D 277/28 (20130101) C07D 277/56 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 413/04 (20130101) C07D 413/06 (20130101) C07D 417/04 (20130101) C07D 417/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865203 | Cook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin); Medical University of Vienna (Vienna, Austria) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin); Medical University of Vienna (Vienna, Austria) |
| INVENTOR(S) | James Cook (Milwaukee, Wisconsin); Daniel Knutson (Elkhorn, Wisconsin); Marko Mihovilovic (Perchtoldsdorf, Austria); Laurin Wimmer (Oberndorf, Austria) |
| ABSTRACT | Provided herein are novel pyrazolo-quinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/578790 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/06 (20180101) A61P 25/18 (20180101) A61P 25/24 (20180101) A61P 27/16 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 491/147 (20130101) C07D 495/14 (20130101) C07D 498/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865204 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Calla M. Olson (Brookline, Massachusetts); Yanke Liang (Brookline, Massachusetts); Nicholas Kwiatkowski (Auburn, Massachusetts); Baishan Jiang (Watertown, Massachusetts); Eric Wang (Jamaica Plain, Massachusetts) |
| ABSTRACT | The present application provides bifunctional compounds of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for cyclin-dependent kinase 4 (CDK4) and/or cyclin-dependent kinase 6 (CDK6). The present application also relates to methods for the targeted degradation of CDK4 and/or CDK6 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK4 and/or CDK6 which can be utilized in the treatment of disorders modulated by CDK4 and/or CDK6. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 16/094098 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865205 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Calla M. Olson (Brookline, Massachusetts); Yanke Liang (Brookline, Massachusetts); Nicholas Kwiatkowski (Auburn, Massachusetts) |
| ABSTRACT | The present application provides bifunctional compounds of Formula (Ia) or (Ib): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for cyclin-dependent kinase 8 (CDK8). The present application also relates to methods for the targeted degradation of CDK8 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK8 which can be utilized in the treatment of disorders modulated by CDK8. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 16/094105 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/18 (20130101) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865213 | Koehler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela N. Koehler (Belmont, Massachusetts); Eric Stefan (Boston, Massachusetts); Francisco Caballero (Brookline, Massachusetts); Dylan Vijith Neel (Providence, Rhode Island); Nicholas B. Struntz (Cambridge, Massachusetts); Helen L. Evans (Cambridge, Massachusetts); Andrew Chen (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of Formula (I′), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxi1 (e.g., inhibitors of Myc, Mad, or Mxi1), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/167238 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 233/28 (20130101) C07D 491/107 (20130101) C07D 498/04 (20130101) Original (OR) Class C07D 498/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865220 | Ebetino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BIOVINC, LLC (Pasadena, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | BIOVINC, LLC (Pasadena, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Frank H. Ebetino (Pasadena, California); Shuting Sun (Pasadena, California); Mark W. Lundy (Pasadena, California); Charles E. McKenna (Pasadena, California); Eric Richard (Pasadena, California); Parish Sedghizadeh (Los Angeles, California); Keivan Sadrerafi (Pasadena, California); Philip T. Cherian (Pasadena, California) |
| ABSTRACT | Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207465 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) A61K 47/548 (20170801) A61K 47/552 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/10 (20180101) A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) C07F 9/65583 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865222 | Schoenhofen et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Research Council of Canada (Ottawa, Canada); University of Massachusetts Medical School (Boston, Massachusetts) |
| ASSIGNEE(S) | National Research Council of Canada (Ottawa, Canada); University of Massachusetts Medical School (Boston, Massachusetts) |
| INVENTOR(S) | Ian Schoenhofen (Stittsville, Canada); Dennis M. Whitfield (Ottawa, Canada); Sanjay Ram (Worchester, Massachusetts) |
| ABSTRACT | N. gonorrhoeae has become resistant to almost every conventional antibiotic. Described herein is the use of CMP-nonulosonate analogues to counter gonococcal complement evasion. The nonulosonate sugar is incorporated into the lipooligosaccharide of the N. gonorrhoeae which in turn reduces the serum resistance of the bacteria. This provides a novel therapeutic strategy against the global threat of multi-drug resistant gonorrhea. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/693852 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865229 | Berglund et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | John A. Berglund (Gainesville, Florida); Melissa Hale (Gainesville, Florida) |
| ABSTRACT | Provided herein are compositions and methods related to treating repeat expansion diseases that feature the sequestration of Muscleblind-like (MBNL) proteins by the toxic repeat RNA transcripts within distinct nuclear foci that are expressed from the expanded repeat tracts. Certain compositions of synthetic MBLN proteins can be used to displace endogenous MBNL from the toxic RNAs or replace endogenous MBNL within the cell for normal function. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 16/308098 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 14/471 (20130101) Original (OR) Class C07K 14/4702 (20130101) C07K 14/4705 (20130101) C07K 16/44 (20130101) C07K 2317/56 (20130101) C07K 2319/09 (20130101) C07K 2319/10 (20130101) C07K 2319/40 (20130101) C07K 2319/60 (20130101) C07K 2319/81 (20130101) C07K 2319/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865233 | Dranoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | Glenn Dranoff (Lexington, Massachusetts); Matthew Vanneman (Boston, Massachusetts); Gordon Freeman (Brookline, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Glenn Dranoff (Lexington, Massachusetts); Matthew Vanneman (Boston, Massachusetts); Gordon Freeman (Brookline, Massachusetts) |
| ABSTRACT | Methods for cancer immunotherapy are provided. The methods involve the use of a chimeric molecule (e.g., fusion protein) comprising an NKG2D portion and an Fc portion, which binds one or more NKG2D ligands. The methods disclosed herein are useful for the treatment of cancer that is associated with abnormal expression of one or more NKG2D ligands. |
| FILED | Friday, December 18, 2009 |
| APPL NO | 13/140469 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 45/06 (20130101) Peptides C07K 14/7056 (20130101) C07K 14/70596 (20130101) Original (OR) Class C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865234 | Chan-Hui et al. |
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| FUNDED BY |
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| APPLICANT(S) | Theraclone Sciences, Inc. (Seattle, Washington); International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THERACLONE SCIENCES, INC. (Seattle, Washington); INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Po-Ying Chan-Hui (Bellevue, Washington); Steven Frey (Redmond, Washington); Ole Olsen (Everett, Washington); Jennifer Mitcham (Redmond, Washington); Matthew Moyle (Redmond, Washington); Sanjay K. Phogat (Frederick, Maryland); Dennis R. Burton (La Jolla, California); Laura Marjorie Walker (San Diego, California); Pascal Raymond Georges Poignard (San Diego, California); Wayne Koff (Stony Brook, New York); Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York); Stephen Kaminsky (Bronx, New York) |
| ABSTRACT | The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/513859 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865252 | Gregory et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Richard I. Gregory (Brookline, Massachusetts); Elena Piskounova (Dallas, Texas); Dimitrios Iliopoulos (Los Angeles, California) |
| ABSTRACT | The present embodiments provide for compositions and methods that regulate microRNA-binding protein-mediated miRNA biogensis; for example Lin28-mediated biogenesis of let-7; and in particular Lin28A-recruited 3′ terminal uridylyl transferase (TUTase) uridylation of pre-let-7. A particular embodiment provide compositions and methods for screening for agents that inhibit TUTase-dependent Lin28A-mediated repression of let-7 miRNA. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 15/913323 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Peptides C07K 2/00 (20130101) C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/10 (20130101) C12N 2320/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865379 | Rafii et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Shahin Rafii (New York, New York); Fan Zhang (Fort Lee, New Jersey); Marco Seandel (New York, New York) |
| ABSTRACT | The present invention relates to adenovirus E4ORF1 gene and to endothelial cells engineered to express the E4ORF1 gene. The present invention also relates to uses of the E4ORF1 gene, and cells expressing the E4ORF1 gene, and to compositions comprising the E4ORF1 gene, or comprising cells expressing the E4ORF1 gene. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/906408 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 5/0647 (20130101) C12N 5/0693 (20130101) C12N 15/1131 (20130101) C12N 15/1136 (20130101) C12N 2310/14 (20130101) C12N 2501/998 (20130101) C12N 2710/10322 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865394 | Naegle et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kristen Naegle (St. Louis, Missouri); Roman Sloutsky (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Kristen Naegle (St. Louis, Missouri); Roman Sloutsky (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides a system to produce soluble, folded, and post-translationally modified proteins. The system includes a fusion protein comprising a catalytic domain of an enzyme involved in post-translational protein modification and a targeting domain, and a substrate protein comprising a protein of interest and a sequence that interacts with the targeting domain. The present disclosure also provides polynucleotide sequences encoding fusion proteins and substrate proteins, vectors for expressing polynucleotide sequences, vectors comprising the polynucleotide sequences, and isolated cells comprising said vectors. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/710451 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865396 | Pomerantz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Richard T. Pomerantz (Brooklyn, New York); Tatiana Kent (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for modifying the 3′-terminal ends of nucleic acids using DNA polymerase θ terminal transferase activity. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/772192 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) Original (OR) Class C12N 2310/344 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2521/131 (20130101) C12Q 2525/101 (20130101) C12Q 2525/101 (20130101) C12Q 2525/101 (20130101) C12Q 2525/117 (20130101) C12Q 2525/121 (20130101) C12Q 2525/173 (20130101) C12Q 2527/125 (20130101) C12Q 2563/107 (20130101) C12Q 2563/137 (20130101) C12Q 2563/137 (20130101) Enzymes C12Y 207/07007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865403 | Georgiou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); Shira Cramer (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the engineering of a protein with L-cyst(e)ine degrading enzyme activity are described. For example, disclosed are modified cystathionine-γ-lyases comprising one or more amino acid substitutions and capable of degrading L-cyst(e)ine. Furthermore, compositions and methods are provided for the treatment of cancer and cystinuria using the disclosed modified enzymes or nucleic acids encoding said enzymes. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977246 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/225 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/7076 (20130101) A61K 31/7076 (20130101) A61K 38/00 (20130101) A61K 38/16 (20130101) A61K 38/38 (20130101) A61K 38/51 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/61 (20170801) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/001 (20130101) C07K 14/76 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class Enzymes C12Y 404/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865419 | Daniell |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 14/353980 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) A61K 38/51 (20130101) A61K 38/162 (20130101) A61K 38/164 (20130101) A61K 38/2278 (20130101) Peptides C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865445 | van der Maarel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Silvere M. van der Maarel (Leiden, Netherlands); Stephen J. Tapscott (Seattle, Washington); Rabi Tawil (Rochester, New York); Richard J. L. F. Lemmers (Leiden, Netherlands); Linda Geng (Seattle, Washington); Lauren Snider (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); University of Rochester (Rochester, New York); Leiden University Medical Center (Leiden, Netherlands) |
| INVENTOR(S) | Silvere M. van der Maarel (Leiden, Netherlands); Stephen J. Tapscott (Seattle, Washington); Rabi Tawil (Rochester, New York); Richard J. L. F. Lemmers (Leiden, Netherlands); Linda Geng (Seattle, Washington); Lauren Snider (Seattle, Washington) |
| ABSTRACT | In one aspect, the invention provides a method of screening a human subject to determine if said subject has a genetic predisposition to develop, or is suffering from Facioscapulohumeral Dystrophy (FSHD), said method comprising: (a) providing a biological sample comprising genomic DNA from the subject; and (b) analyzing the portion of the genomic DNA in the sample corresponding to the distal D4Z4-pLAM region on chromosome 4 and determining the presence or absence of a polymorphism resulting in a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene, wherein a determination of the absence of a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene indicates that the subject does not have a genetic predisposition to develop, and is not suffering from FSHD, and/or wherein a determination of the presence of a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene indicates that the subject has a genetic predisposition to develop, or is suffering from Facioscapulohumeral Dystrophy (FSHD). |
| FILED | Thursday, August 18, 2011 |
| APPL NO | 13/817531 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 48/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/326 (20130101) A61N 1/36003 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 2319/71 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2320/11 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101) C12N 2330/51 (20130101) C12N 2501/60 (20130101) C12N 2710/10043 (20130101) C12N 2750/00032 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6897 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/6896 (20130101) G01N 2800/2878 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865446 | Kaminsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF MARYLAND (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Zachary Kaminsky (Baltimore, Maryland); Jennifer L. Payne (Baltimore, Maryland); Todd Gould (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of post-partum depression. More specifically, the present invention relates to the use of biomarkers to diagnose post-partum depression or predict a risk thereof. In a specific embodiment, a method for identifying a likelihood of PPD in a patient comprises the steps of (a) providing a sample from the patient; (b) measuring white blood cell type counts and DNA methylation levels of a panel of biomarkers in the sample collected from the patient, wherein the panel of biomarkers comprises HP1BP3 and TTC9B and the white blood cell type counts comprise monocytes and non-monocytes; and (c) identifying the patient as likely to develop PPD based on the relative DNA methylation levels at the biomarker loci relative to the ratio of monocytes:non-monocytes. |
| FILED | Monday, November 04, 2013 |
| APPL NO | 14/439468 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 2015/008 (20130101) G01N 2015/1062 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865448 | McAllister et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania); VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania); VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Janette M McAllister (Hummelstown, Pennsylvania); Jerome F Strauss (Richmond, Virginia) |
| ABSTRACT | Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product. |
| FILED | Thursday, March 15, 2018 |
| APPL NO | 15/921712 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865451 | Janne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Pasi A. Janne (Needham, Massachusetts); Cloud P. Paweletz (Boston, Massachusetts); Geoffrey Oxnard (Arlington, Massachusetts); Yanan Kuang (Belmont, Massachusetts) |
| ABSTRACT | The invention provides methods to monitor cell free nucleic acids. The method comprises obtaining a plasma sample from a subject known to have a cancer characterized by a pair of mutually exclusive mutations specific to the cancer; isolating cell free nucleic acids from the plasma sample obtained from the subject; measuring the amount a housekeeping gene and/or total DNA in the cell free nucleic acids isolated from the plasma sample to confirm that the amount of housekeeping gene and/or total DNA in the sample is within a selected range; measuring the amount of a first of the pair of mutually exclusive mutations specific to the cancer in the cell free nucleic acids isolated from the plasma sample; and indicating in a report that the subject has the first mutation when (a) the amount of the housekeeping gene and/or total DNA in the cell free nucleic acids isolated from the plasma sample is within the selected range and (b) the amount of the first mutation is increased as compared to a control amount, wherein the control amount is determined by measuring the apparent amount of the first mutation in control cell free nucleic acids isolated from plasma samples obtained from control subjects known to have the second of the pair of mutually exclusive mutations specific to the cancer using measuring conditions substantially the same as those used to measure the amount of the first mutation in the cell free nucleic acids isolated from the plasma sample from the subject. |
| FILED | Wednesday, June 11, 2014 |
| APPL NO | 14/897269 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2545/101 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865818 | Frohnapfel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dustin J. Frohnapfel (Blacksburg, Virginia); Walter F. O'Brien, Jr. (Blacksburg, Virginia); K. Todd Lowe (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Dustin J. Frohnapfel (Blacksburg, Virginia); Walter F. O'Brien, Jr. (Blacksburg, Virginia); K. Todd Lowe (Blacksburg, Virginia) |
| ABSTRACT | Various examples are provided related to improvements in generalized flow profile production. In one example, a method includes determining a downstream flow profile including a pressure profile and a velocity profile; fabricating a pressure profile generator including distortion screen(s) disposed on a backing structure; fabricating a velocity profile generator including turning vanes in a flow path through the velocity profile generator that are configured to generate the velocity profile; attaching the pressure profile generator to an input side of the velocity profile generator; and installing the flow conditioning device in the flow field of interest. Flow through the flow conditioning device produces the downstream flow profile in the flow field of interest. In another example, a flow conditioning device includes a pressure profile generator with distortion screen(s) disposed on a backing structure; and a velocity profile generator with turning vanes attached to an input side of the velocity profile generator. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 16/099389 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/001 (20130101) Original (OR) Class F15D 1/02 (20130101) F15D 1/025 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866184 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Jesus Rodriguez Manzano (London, United Kingdom); Mikhail Karymov (San Jose, Canada); David A. Selck (Sterling, Virginia); Stefano Begolo (Inglewood, California); Erik B. Jue (Moorpark, California); Dmitriy V. Zhukov (Pasadena, California) |
| ABSTRACT | The present invention relates to methods, computer readable medium and systems for detecting and counting single nucleic acid molecules confined in nanoliter volumes using an unmodified camera, such as a cell phone camera. In particular, it identifies colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones. The invention further provides an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/774004 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2527/101 (20130101) C12Q 2537/165 (20130101) C12Q 2563/159 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/46 (20130101) G01J 3/50 (20130101) G01J 3/0272 (20130101) G01J 3/463 (20130101) G01J 2003/468 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/253 (20130101) Original (OR) Class G01N 2201/0221 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 7/90 (20170101) G06T 2207/10012 (20130101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866230 | Grinstaff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Mark Grinstaff (Brookline, Massachusetts); Amit Meller (Brookline, Massachusetts); Joseph Hersey (Cambridge, Massachusetts); Allison Squires (Allston, Massachusetts) |
| ABSTRACT | Provided herein are compositions, compounds, processes, and methods of use of 3D porous coating(s) on or near a nanopore(s) for analysis or detection of charged polymers such as nucleic acids, proteins, protein-nucleic acid complexes, small molecule-biological complexes, polymer-biological complexes, and/or polyelectrolytes. |
| FILED | Friday, May 30, 2014 |
| APPL NO | 14/895714 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/007 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/0427 (20200101) C08J 2309/02 (20130101) C08J 2477/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44747 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866239 | Lampe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Paul Lampe (Seattle, Washington); Junghyun Rho (Auckland, New Zealand) |
| ABSTRACT | The present disclosure provides methods of using certain biomarker expression profiles in the detection, diagnosis, prognosis, or development of treatment regimens for various cellular hyperproliferative disorders of the bowel. For example, pre-diagnostic methods comprise detecting whether the concentration of at least BAG4 in a test biological sample from a subject is elevated as compared to a control. |
| FILED | Friday, September 04, 2015 |
| APPL NO | 15/506466 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) Original (OR) Class G01N 2333/4703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866249 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| INVENTOR(S) | Gale W. Newman (Duluth, Georgia); Barbara A. Jacob-Mungin (Atlanta, Georgia); Chamberlain Obialo (Atlanta, Georgia) |
| ABSTRACT | The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed. |
| FILED | Thursday, May 30, 2013 |
| APPL NO | 13/906074 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/40 (20130101) A61K 31/422 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4025 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/78 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/56988 (20130101) G01N 2333/5754 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867706 | Hillis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Invention, LLC (Glendale, California); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | APPLIED INVENTION, LLC (Glendale, California); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | William Daniel Hillis (Encino, California); David B. Agus (Beverly Hills, California) |
| ABSTRACT | Described herein are methods and systems to measure dynamics of disease progression, including cancer growth and response, at multiple scales by multiple techniques on the same biologic system. Methods and systems according to the invention permit personalized virtual disease models. Moreover, the invention allows for the integration of previously unconnected data points into an in silico disease model, providing for the prediction of disease progression with and without therapeutic intervention. |
| FILED | Thursday, August 13, 2015 |
| APPL NO | 14/826049 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 20/00 (20190201) G16B 99/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868202 | Goldan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Amirhossein Goldan (Stony Brook, New York); Wei Zhao (East Setauket, New York) |
| ABSTRACT | Provided is a field shaping multi-well detector and method of fabrication thereof. The detector is configured by depositing a pixel electrode on a substrate, depositing a first dielectric layer, depositing a first conductive grid electrode layer on the first dielectric layer, depositing a second dielectric layer on the first conductive grid electrode layer, depositing a second conductive grid electrode layer on the second dielectric layer, depositing a third dielectric layer on the second conductive grid electrode layer, depositing an etch mask on the third dielectric layer. Two pillars are formed by etching the third dielectric layer, the second conductive grid electrode layer, the second dielectric layer, the first conductive grid electrode layer, and the first dielectric layer. A well between the two pillars is formed by etching to the pixel electrode, without etching the pixel electrode, and the well is filled with a-Se. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845471 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1461 (20130101) H01L 27/1463 (20130101) H01L 27/14612 (20130101) H01L 27/14632 (20130101) H01L 27/14636 (20130101) H01L 27/14643 (20130101) H01L 27/14659 (20130101) H01L 27/14692 (20130101) H01L 27/14696 (20130101) H01L 31/105 (20130101) H01L 31/107 (20130101) H01L 31/0272 (20130101) Original (OR) Class H01L 31/0376 (20130101) H01L 31/02161 (20130101) H01L 31/022408 (20130101) H01L 31/035209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868284 | Laulicht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Bryan Laulicht (Danbury, Connecticut); Janet Freilich (Washington, District of Columbia); Jeffrey M. Karp (Brookline, Massachusetts); Robert Langer (Newton, Massachusetts) |
| ABSTRACT | A battery for use in electronic devices and which is safely ingested into a body and a related method of making the battery. The battery includes an anode, a cathode and a quantum tunneling composite coating. The quantum tunneling composite coating covers at least a portion of at least one of the anode or the cathode and provides pressure sensitive conductive properties to the battery including a compressive stress threshold for conduction. The compressive stress threshold may be greater than a pre-determined applied stress in a digestive tract of the body in order to prevent harm if the battery is ingested. The battery may include a waterproof seal that extends between the quantum tunneling composite coating and a gasket separating the anode and cathode to inhibit the battery from short circuiting in a conductive fluid below the compressive stress threshold. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 16/504970 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/08 (20130101) H01M 2/18 (20130101) H01M 2/025 (20130101) H01M 2/30 (20130101) H01M 2/34 (20130101) H01M 2/0222 (20130101) Original (OR) Class H01M 2/0267 (20130101) H01M 10/4235 (20130101) H01M 2200/00 (20130101) H01M 2200/20 (20130101) H01M 2220/00 (20130101) H01M 2220/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10863895 | Jarrahi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mona Jarrahi (Los Angeles, California) |
| ABSTRACT | Terahertz imaging systems for endoscopy are provided. Terahertz imaging systems can be utilized in scanning tissue. Terahertz imaging systems in accordance with embodiments of the invention can include terahertz sources, terahertz detectors, and/or rotating elements. The terahertz sources can generate terahertz radiation and have plasmonic contact electrodes that can be illuminated by optical pump beams. The terahertz detectors can receive terahertz field data. The terahertz source and detector can be arranged in an array. The rotating elements can be mirror mounted at a particular angle on a micromotor. The terahertz source, rotating element, and terahertz detector can be arranged in an catheter. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/577222 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/05 (20130101) A61B 1/063 (20130101) Original (OR) Class A61B 1/00188 (20130101) A61B 1/00195 (20130101) A61B 1/0676 (20130101) A61B 1/2676 (20130101) A61B 1/2736 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14601 (20130101) H01L 31/08 (20130101) H01L 31/0224 (20130101) H01L 31/03042 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864387 | MacKay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jake Travis MacKay (Tuscaloosa, Alabama); Brent Gilbert (Birmingham, Alabama); Logan Brost (Benbrook, Texas); Richard Gilliland (Hoover, Alabama); Mark Morgan Pelt (Ogden, Utah); Caleb Clemons (Huntsville, Alabama); Zachary Martin (Charlotte, North Carolina); Wesley S. Hunko (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | Jake Travis MacKay (Tuscaloosa, Alabama); Brent Gilbert (Birmingham, Alabama); Logan Brost (Benbrook, Texas); Richard Gilliland (Hoover, Alabama); Mark Morgan Pelt (Ogden, Utah); Caleb Clemons (Huntsville, Alabama); Zachary Martin (Charlotte, North Carolina); Wesley S. Hunko (Auburn, Alabama) |
| ABSTRACT | Disclosed is a hinged, two-wheeled device for improving the safety of an individual or object descending along a rope from an elevated position. The device includes a two-piece hinged framed held open by a torsion spring. Each part of the frame contains a wheel with a cut out/channel with a knurled surface to increase the friction between the rope and the device and to prevent the device from disengaging during use. The rope is placed between the two wheels and the handle is pulled down, clamping the device around the rope. The two wheels are connected to viscous rotary dampers that slow the speed of the wheels during descent, preventing the user/object from accelerating in a free-fall and controlling the descent rate to a relatively constant, safer speed. |
| FILED | Thursday, April 19, 2018 |
| APPL NO | 15/956906 |
| ART UNIT | 3634 — Static Structures, Supports and Furniture |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 1/12 (20130101) A62B 1/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864520 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); William Hampton Henley (Chapel Hill, North Carolina); Joseph Carl Gaiteri (Chapel Hill, North Carolina) |
| ABSTRACT | Embodiments of the invention provide fluidic devices such as, but not limited to, microfluidic chips, with one or more freeze thaw valves (FTVs) employing one or more ice-nucleating agents (INAs), that can reliably operate to freeze at relatively higher temperatures and/or at faster rates than conventional microfluidic devices with FTV systems. |
| FILED | Friday, July 22, 2016 |
| APPL NO | 15/742662 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 7/50 (20130101) Original (OR) Class B01L 2300/0816 (20130101) B01L 2300/1894 (20130101) B01L 2400/0677 (20130101) Peptides C07K 14/21 (20130101) C07K 14/27 (20130101) C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0032 (20130101) F16K 99/0036 (20130101) F16K 99/0044 (20130101) F16K 2099/0084 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864567 | Pingilley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Army (, None) |
| INVENTOR(S) | John D. Pingilley (Bettendorf, Iowa); Amanda L. Badger (Eldridge, Iowa); Dale A. Phipps (Taylor Ridge, Illinois) |
| ABSTRACT | A guide system for use in electro-processing a bore of a gun barrel includes a non-conductive external bore guide and a non-conductive internal bore guide. The external bore guide is an adapter that is configured to removably engage the outside of the gun barrel and includes a conduit formed therein. The conduit is disposed such that it is axially aligned with a bore of the gun barrel when the external bore guide is engaged with the gun barrel. The internal bore guide is elongated and includes an axial recess that is sized to seat an electro-processing electrode (an anode). A method for uniformly plating the bore includes moving an anode through the gun barrel at one or more rate(s) of travel to uniformly plate the bore is also disclosed. The plating is sufficiently uniform to conform to military specifications. The systems, methods, support structures, etc. described herein are particularly well-suited to plating small-bore gun barrels. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384109 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/152 (20130101) Original (OR) Class Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/02 (20130101) F41A 21/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864857 | Hollis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael Hollis (Flanders, New Jersey); Christopher Mougeotte (Westminster, Maryland); Jeffrey Van Derveer (Randolph, New Jersey); Nicholas Stolten (Bangor, Pennsylvania); Kris Mayer (Blairstown, New Jersey) |
| ABSTRACT | A weapon stowage and mounting system for a military vehicle, wherein the weapon stowage and mounting system secures a weapon such as an M16 or M249 emplaced therein and retains such weapon from flying about as a secondary projectile in the event of a vehicle roll over, vehicle collision or vehicle blast event, The weapon stowage and mounting system allows for stowage of a weapon with loaded ammunition magazines, grenade launchers, forward hand grips, and/or rails and scopes still attached to the weapon, thus allowing maintenance of constant mission readiness. The weapon stowage and mounting system also includes a panel of UMWPE material that is positioned in line with the muzzle of a stowed weapon to fully capture a bullet in the event of an accidental discharge of the weapon. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/387868 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 7/04 (20130101) B60R 7/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864987 | Ulrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Evan Robert Ulrich (Hermosa Beach, California); Robert Edward Oberto (Manhattan Beach, California) |
| ABSTRACT | An aircraft that includes torque rotor and a lifting rotor, and generates torque from the torque rotor. The torque rotor may optimize drag production while the lifting rotor may optimize lift production limiting compromise between drag and lift production rotor. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724526 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) B64C 27/78 (20130101) B64C 27/82 (20130101) Original (OR) Class B64C 2027/8272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865196 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee); ONCTERNAL THERAPEUTICS, INC (San Diego, California) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); ONCTERNAL THERAPEUTICS, INC. (San Diego, California) |
| INVENTOR(S) | Duane D. Miller (Collierville, Tennessee); Jianjun Chen (Knoxville, Tennessee); James T. Dalton (Ann Arbor, Michigan); Chien-Ming Li (Fremont, California); Sunjoo Ahn (Yuseong-gu Daejeon, South Korea); Wei Li (Germantown, Tennessee) |
| ABSTRACT | The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872199 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/421 (20130101) A61K 31/426 (20130101) A61K 31/4178 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 233/02 (20130101) C07D 233/22 (20130101) C07D 233/54 (20130101) C07D 263/06 (20130101) C07D 263/14 (20130101) C07D 263/32 (20130101) C07D 277/04 (20130101) C07D 277/24 (20130101) C07D 277/28 (20130101) C07D 277/56 (20130101) C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 413/04 (20130101) C07D 413/06 (20130101) C07D 417/04 (20130101) C07D 417/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865235 | Ingber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Michael Super (Lexington, Massachusetts); Jeffrey Charles Way (Cambridge, Massachusetts); Mark J. Cartwright (West Newton, Massachusetts); Julia B. Berthet (Brookline, Massachusetts); Dinah R. Super (Lexington, Massachusetts); Martin Rottman (St. Cloud, France); Alexander L. Watters (Melrose, Massachusetts) |
| ABSTRACT | Described herein are engineered microbe-targeting or microbe-binding molecules, kits comprising the same and uses thereof. Some particular embodiments of the microbe-targeting or microbe-binding molecules comprise a carbohydrate recognition domain of mannose-binding lectin, or a fragment thereof, linked to a portion of a Fc region. In some embodiments, the microbe-targeting molecules or microbe-binding molecules can be conjugated to a substrate, e.g., a magnetic microbead, forming a microbe-targeting substrate (e.g., a microbe-targeting magnetic microbead). Such microbe-targeting molecules and/or substrates and the kits comprising the same can bind and/or capture of a microbe and/or microbial matter thereof, and can thus be used in various applications, e.g., diagnosis and/or treatment of an infection caused by microbes such as sepsis in a subject or any environmental surface. Microbe-targeting molecules and/or substrates can be regenerated after use by washing with a low pH buffer or buffer in which calcium is insoluble. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683630 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/68 (20170801) A61K 47/6815 (20170801) Peptides C07K 14/42 (20130101) C07K 16/12 (20130101) Original (OR) Class C07K 2319/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54353 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 33/56938 (20130101) G01N 33/56961 (20130101) G01N 2333/42 (20130101) G01N 2333/4724 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865306 | Esser-Kahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Aaron P. Esser-Kahn (Champaign, Illinois); Hefei Dong (Urbana, Illinois); Piyush R. Thakre (Lake Jackson, Texas); Jason F. Patrick (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois) |
| ABSTRACT | A microvascular system includes a solid polymeric matrix and a woven structure in the matrix. The woven structure includes a plurality of fibers, and a plurality of microfluidic channels, where at least a portion of the microfluidic channels are interconnected. The microvascular system may be made by forming a composite that includes a solid polymeric matrix and a plurality of sacrificial fibers in the matrix, heating the composite to a temperature of from 100 to 250° C., maintaining the composite at a temperature of from 100 to 250° C. for a time sufficient to form degradants from the sacrificial fibers, and removing the degradants from the composite. The sacrificial fibers may include a polymeric fiber matrix including a poly(hydroxyalkanoate) and a metal selected from the group consisting of an alkali earth metal and a transition metal, in the fiber matrix, where the concentration of the metal in the fiber matrix is at least 0.1 wt %. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/960076 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/023 (20190201) B29C 67/202 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/20 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/04 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2958 (20150115) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865316 | Mount et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Andrew Mount (Clemson, South Carolina); Bin San Chan (Hong Kong, China PRC); Mary Beth Johnstone (Clemson, South Carolina) |
| ABSTRACT | Materials and methods for prevention of biofouling that incorporate the presence of a conotoxin peptide on a surface are described. The conotoxin peptide is either directly or indirectly adhered to the surface and interferes with the ability of biofouling organisms to settle on the surface. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685101 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 2303/20 (20130101) Peptides C07K 7/08 (20130101) C07K 14/43504 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865440 | Eberhart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEGENX INC. (Pleasanton, California) |
| ASSIGNEE(S) | IntegenX, Inc. (Pleasanton, California) |
| INVENTOR(S) | David Eberhart (Santa Clara, California); Yuan Li (Dublin, California); James Ogg (Sunnyvale, California); Ezra Van Gelder (Palo Alto, California); Stephen J. Williams (San Carlos, California); Timothy Woudenberg (San Francisco, California); Dean S. Burgi (Sunnyvale, California); William D. Nielsen (San Jose, California) |
| ABSTRACT | This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module. |
| FILED | Thursday, February 28, 2013 |
| APPL NO | 14/381179 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/527 (20130101) B01L 3/5029 (20130101) B01L 3/502715 (20130101) B01L 7/52 (20130101) B01L 2200/04 (20130101) B01L 2200/025 (20130101) B01L 2200/028 (20130101) B01L 2200/143 (20130101) B01L 2200/0647 (20130101) B01L 2200/0684 (20130101) B01L 2300/023 (20130101) B01L 2300/027 (20130101) B01L 2300/123 (20130101) B01L 2300/0672 (20130101) B01L 2400/043 (20130101) B01L 2400/0421 (20130101) B01L 2400/0478 (20130101) B01L 2400/0616 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/686 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44704 (20130101) G01N 2035/00158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865582 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Justin M Roberts (Florence, Mississippi); Craig R Ackerman (Gainesville, Virginia) |
| ABSTRACT | In one embodiment, a flashing system is provided for fortifying seams between a first blast, ballistic, and forced entry resistant shelter module and a second blast, ballistic, and forced entry resistant shelter module. The system includes a first side flashing assembly for fortifying a first side seam between the first blast, ballistic, and forced entry resistant shelter module and the second blast, ballistic, and forced entry resistant shelter module, a top flashing assembly for fortifying a top seam between the first blast, ballistic, and forced entry resistant shelter module and the second blast, ballistic, and forced entry resistant shelter module, and a second side flashing assembly for fortifying a second side seam between the first blast, ballistic, and forced entry resistant shelter module and the second blast, ballistic, and forced entry resistant shelter module. The system can also include fastening assemblies for coupling the flashing assemblies with the blast, ballistic, and forced entry resistant shelter modules. |
| FILED | Thursday, December 13, 2018 |
| APPL NO | 16/219858 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/348 (20130101) Finishing Work on Buildings, e.g Stairs, Floors E04F 19/02 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865644 | Walker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KEYSTONE SYNERGISTIC ENTERPRISES, INC. (Port Saint Lucie, Florida) |
| ASSIGNEE(S) | KEYSTONE SYNERGISTIC ENTERPRISES, INC. (Port Saint Lucie, Florida) |
| INVENTOR(S) | Bryant Walker (Palm City, Florida); Raymond Walker (Port Saint Lucie, Florida) |
| ABSTRACT | A rotor for use in an aircraft engine, that has been repaired by (a) welding together a first portion of a damaged blade of the rotor and a second portion of metal to form a weld nugget, (b) compressively stressing the weld nugget throughout its volume, and (c) heat treating the compressively stressed weld nugget to recrystallize metal therein. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467173 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0006 (20130101) B23K 15/0093 (20130101) B23K 26/0006 (20130101) B23K 26/20 (20130101) B23K 26/21 (20151001) B23K 2101/001 (20180801) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/005 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/005 (20130101) Original (OR) Class F01D 5/147 (20130101) Jet-propulsion Plants F02K 9/52 (20130101) F02K 9/58 (20130101) F02K 9/62 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/41 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49318 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865818 | Frohnapfel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dustin J. Frohnapfel (Blacksburg, Virginia); Walter F. O'Brien, Jr. (Blacksburg, Virginia); K. Todd Lowe (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Dustin J. Frohnapfel (Blacksburg, Virginia); Walter F. O'Brien, Jr. (Blacksburg, Virginia); K. Todd Lowe (Blacksburg, Virginia) |
| ABSTRACT | Various examples are provided related to improvements in generalized flow profile production. In one example, a method includes determining a downstream flow profile including a pressure profile and a velocity profile; fabricating a pressure profile generator including distortion screen(s) disposed on a backing structure; fabricating a velocity profile generator including turning vanes in a flow path through the velocity profile generator that are configured to generate the velocity profile; attaching the pressure profile generator to an input side of the velocity profile generator; and installing the flow conditioning device in the flow field of interest. Flow through the flow conditioning device produces the downstream flow profile in the flow field of interest. In another example, a flow conditioning device includes a pressure profile generator with distortion screen(s) disposed on a backing structure; and a velocity profile generator with turning vanes attached to an input side of the velocity profile generator. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 16/099389 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/001 (20130101) Original (OR) Class F15D 1/02 (20130101) F15D 1/025 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865899 | Wiedemeier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brandon J. Wiedemeier (San Diego, California); Jesse T. Caldwell (Alpine, California) |
| ABSTRACT | A system and method for protecting a lightweight pressure vessel capable of airborne and underwater use. The system includes an enclosure and a gas container that is capable of holding pressurized or liquefied gas in sufficient quantity to increase internal pressure of the pressure vessel, so that the internal pressure of the pressure vessel equals an external pressure of the pressure vessel. The system also includes a pressure relief device coupled to the enclosure. The pressure relief device is configured to release the pressurized or liquefied gas from the pressure vessel when the internal pressure exceeds the external pressure by a predetermined amount. The system also includes a gas supply mechanism coupled to the gas container, the gas supply mechanism being configured to allow gas from the gas container into order to increase the internal pressure of the pressure vessel until the internal pressure equals the external pressure. |
| FILED | Thursday, September 27, 2018 |
| APPL NO | 16/143616 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/003 (20130101) Original (OR) Class F16K 17/048 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 2205/0332 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/2036 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865901 | Cleveland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Kenneth D. Cleveland (Hollis, New Hampshire); Joseph A. Colosimo (Lexington, New Hampshire); Michael J. Patrick (Andover, Massachusetts); John A. Talbourdet (Danvers, Massachusetts) |
| ABSTRACT | A pressure relief valve having two rigid sealing surfaces lapped to a smoothness Ra of 8 micro-inches or less, and flatness within 80 micro-inches, forms a reliable seal by direct contact therebetween without an elastomer. The sealing surfaces and surrounding structures can be made of one or more metals, such as alloys of stainless steel, and can be CTE-matched, so that the valve is not impeded by environmental temperature changes. In a disclosed embodiment, a “poppet” is axially pressed against a seal plate by a spring. The poppet can be axially stabilized by sliding within a surrounding cylinder or spacer, and can contact the surrounding surface with a plurality of “arms” that reduce friction and enable gas flow therebetween. The poppet can be made from anti-galling Nitronic 60 alloy, and the surrounding structures can be stainless steel. Embodiments are suitable for low-pressure gas applications in extreme environments. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/185868 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/147 (20130101) F16K 17/08 (20130101) F16K 17/0413 (20130101) Original (OR) Class F16K 17/0426 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865942 | Banerjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEXGEN COMPOSITES LLC (Franklin, Ohio) |
| ASSIGNEE(S) | NEXGEN COMPOSITES LLC (Franklin, Ohio) |
| INVENTOR(S) | Robin Banerjee (Centerville, Ohio); Robert L. Lapoint (Charleston, South Carolina); Michael S. Sheppard (Centerville, Ohio) |
| ABSTRACT | According to aspects of the present disclosure, a process of fabricating a unitized container panel is disclosed. The unitized container panel is fabricated by forming a multilayer insulated panel, which has opposing external layers and an intermediate layer therebetween. The intermediate layer is a combination of an insulation material (e.g., vacuum insulated panel, aerogel, etc.), and a buffer material (e.g., a foam board, polystyrene, fiberglass, minerals, plastic, natural fibers, wood, plastic, etc.) that bounds the insulation material. Pressure is applied about the multilayer insulated panel for a predetermined process time, causing the external layers to encase the intermediate layer. After elapse of the predetermined process time, the pressure is released about the multilayer insulated panel, thereby resulting in a unitized container panel. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172242 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 90/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/344 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/12 (20130101) F17C 3/027 (20130101) Original (OR) Class F17C 2201/052 (20130101) F17C 2203/0358 (20130101) F17C 2203/0391 (20130101) F17C 2203/0626 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866096 | Stanley-Marbell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Phillip Stanley-Marbell (Boston, Massachusetts); Martin C. Rinard (Arlington, Massachusetts) |
| ABSTRACT | A sensor produces the sensor data for a sensor data consumer. A device receives a sensor profile of the sensor indicating a relationship between a sensor parameter operating range and a deviation of the sensor data as a result of scaling one or more sensor parameters. The device receives a tolerance profile of the sensor data consumer indicating a tolerable degree of deviation of the sensor data and scales a parameter of the sensor according to the tolerance profile. The scaling reduces a power dissipation level of the sensor. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/710221 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/112 (20130101) A61B 5/1123 (20130101) A61B 2560/0209 (20130101) A61B 2560/0242 (20130101) A61B 2562/0219 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/10 (20130101) Original (OR) Class G01C 22/006 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) G01P 15/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866099 | Mazilu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Mazilu (St. Andrews, United Kingdom); Joanna Ptasinski (San Diego, California); Alexandru Hening (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Mazilu (St. Andrews, United Kingdom); Joanna Ptasinski (San Diego, California); Alexandru Hening (San Diego, California) |
| ABSTRACT | A gyroscope and method for navigating using the gyroscope can include a substrate that can define a cavity. The cavity can be placed under a vacuum, and a birefringent microrotor can be located in the cavity. A light source can direct light through the substrate and into the cavity to establish an optical spring effect, which act on the microrotor to establish an initial reference position, as well as to establish rotational and translational motion of said microrotor. A receiver can detect light that has passed through said cavity. Changes in light patterns that can be detected at the receiver can be indicative of a change in position of the microrotor. The change and rate of change in position of the microrotor can be used for inertial navigation. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/427579 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/04 (20130101) G01C 19/5656 (20130101) G01C 19/5677 (20130101) G01C 19/5712 (20130101) G01C 19/5726 (20130101) Original (OR) Class Transmission H04B 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866184 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Jesus Rodriguez Manzano (London, United Kingdom); Mikhail Karymov (San Jose, Canada); David A. Selck (Sterling, Virginia); Stefano Begolo (Inglewood, California); Erik B. Jue (Moorpark, California); Dmitriy V. Zhukov (Pasadena, California) |
| ABSTRACT | The present invention relates to methods, computer readable medium and systems for detecting and counting single nucleic acid molecules confined in nanoliter volumes using an unmodified camera, such as a cell phone camera. In particular, it identifies colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones. The invention further provides an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/774004 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2527/101 (20130101) C12Q 2537/165 (20130101) C12Q 2563/159 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/46 (20130101) G01J 3/50 (20130101) G01J 3/0272 (20130101) G01J 3/463 (20130101) G01J 2003/468 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/253 (20130101) Original (OR) Class G01N 2201/0221 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 7/90 (20170101) G06T 2207/10012 (20130101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10866190 — Three-dimensional coherent plasmonic nanowire arrays for enhancement of optical processes
| US 10866190 | Caldwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joshua D. Caldwell (Nashville, Tennessee); Orest J. Glembocki (Alexandria, Virginia); Sharka M. Prokes (Columbia, Maryland); Ronald W. Rendell (Washington, District of Columbia) |
| ABSTRACT | A plasmonic grating sensor having periodic arrays of vertically aligned plasmonic nanopillars, nanowires, or both with an interparticle pitch ranging from λ/8-2λ, where λ is the incident wavelength of light divided by the effective index of refraction of the sample; a coupled-plasmonic array sensor having vertically aligned periodic arrays of plasmonically coupled nanopillars, nanowires, or both with interparticle gaps sufficient to induce overlap between the plasmonic evanescent fields from neighboring nanoparticles, typically requiring edge-to-edge separations of less than 20 nm; and a plasmo-photonic array sensor having a double-resonant, periodic array of vertically aligned subarrays of 1 to 25 plasmonically coupled nanopillars, nanowires, or both where the subarrays are periodically spaced at a pitch on the order of a wavelength of light. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/200992 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866220 | Gianchandani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Yogesh B. Gianchandani (Ann Arbor, Michigan); Yutao Qin (Ann Arbor, Michigan) |
| ABSTRACT | In order to achieve a system capable of analyzing a wide range of compounds while saving time and energy consumption, a progressive cellular architecture is presented for vapor collection and gas chromatographic separation. Each cell includes a preconcentrator and separation column that are adapted for collecting and separating compounds only within a specific volatility range. A wide volatility range can therefore be covered by the use of multiple cells that are cascaded in the appropriate order. The separation columns within each cell are short enough to reduce the heating and pumping requirements. The gas flow for vapor collection and separation is provided by low-power gas micropumps that use ambient air. The system is also configurable to incorporate capabilities of detecting and reducing vapor overload. The progressive cellular architecture directly address the compromise between low power and broad chemical analyses. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978744 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/78 (20130101) G01N 30/461 (20130101) G01N 30/6095 (20130101) Original (OR) Class G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866258 | Reinke |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | John Reinke (Plymouth, Minnesota) |
| ABSTRACT | A vibrating beam accelerometer (VBA) with an in-plane translational proof mass that may include at least two or more resonators and be built with planar geometry, discrete lever arms, four-fold symmetry and a single primary mechanical anchor between the support base and the VBA. In some examples, the VBA of this disclosure may be built according to a micro-electromechanical systems (MEMS) fabrication process. Use of a single primary mechanical anchor may minimize bias errors that can be caused by external mechanical forces applied to the circuit board, package, and/or substrate that contains the accelerometer mechanism. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/041187 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/0235 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/162 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/032 (20130101) Original (OR) Class G01P 15/097 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/083 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/2473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866360 | Khorasaninejad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mohammadreza Khorasaninejad (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | A phase shift element includes a substrate and a dielectric ridge waveguide (DRW) disposed on the substrate. The DRW includes a dielectric material, and a width of the DRW is less than 500 nanometers (nm). A meta-grating includes a substrate and multiple dielectric ridge wave-guides (DRWs) disposed on the substrate. |
| FILED | Thursday, August 18, 2016 |
| APPL NO | 15/745925 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 6/107 (20130101) G02B 6/124 (20130101) Original (OR) Class G02B 2006/12061 (20130101) G02B 2006/12078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866877 | Harer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacob Harer (Mansfield, Massachusetts); Tomo Lazovich (Cambridge, Massachusetts); Rebecca Russell (Cambridge, Massachusetts); Onur Ozdemir (Arlington, Massachusetts); Louis Kim (Cambridge, Massachusetts) |
| ABSTRACT | A software instruction code repair system comprising an instruction code example pool. The example pool comprises a set of good instruction code examples and a set of bad instruction code examples. The software instruction code repair system further comprises a sequence-to-sequence (seq2seq) network that is configured to generate a corrected instruction code example, based on one example of the set of bad instruction code examples. The software instruction code repair system further comprises a discriminator configured to randomly select one of the corrected instruction code example and one instruction code example of the set of good instruction code examples to produce a selected instruction code example. The discriminator is further configured to make a determination that the selected instruction code example is most likely taken either the instruction code example pool or the seq2seq network. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/189353 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3604 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867208 | Lamkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Thomas Lamkin (Fairfield, Ohio); Patrick McLendon (Loveland, Ohio); Daniel Cowan (Beavercreek, Ohio); Robert Trevino (Wailuku, Hawaii) |
| ABSTRACT | A high content analysis computing system, computer program product and method provides receiving two or more sets of microscopic images of respective sites of selected biological cell assay. Each set of microscopic images comprises one or more images having an aggregate field of view sufficient to encompass all of the cells within the respective site and a resolution sufficient to image cellular bodies within each of encompassed cells. For each set of microscopic images, a library of algorithms is executed that evaluate image features for each cell in each site producing a quantified feature measurement for each cell. Quantified feature measurements are compared for each one of the two or more sets of microscopic images. A subset of the library of algorithms is identified that discriminate at least two of the two sets or more microscopic images and deployed as a computer program product for evaluating additional biological cell assays. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103064 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00147 (20130101) G06K 9/6227 (20130101) Original (OR) Class G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 2207/10056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867719 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Andong Liu (Brookline, Massachusetts); Karen K. Gleason (Cambridge, Massachusetts); T. Alan Hatton (Sudbury, Massachusetts); Xianwen Mao (Ithaca, New York) |
| ABSTRACT | Disclosed are compositions of electroactive polymers (EAPs) having improved performance stability. In the EAP compositions, a cross-linked polymer is deposited onto the surface of the EAP by vapor-deposition methods. Upon contact with an aqueous solution (e.g., an aqueous electrolyte solution), the vapor-deposited polymeric network becomes a hydrogel that encapsulates the EAPs. By modulating precursors and vapor deposition conditions, the mesh size of the resultant hydrogel coatings can be controlled to accommodate the key species that interact with the EAPs. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/036010 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 120/20 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/00 (20130101) C08G 61/124 (20130101) C08G 61/126 (20130101) C08G 2261/19 (20130101) C08G 2261/3221 (20130101) C08G 2261/3223 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/00 (20130101) H01B 1/124 (20130101) H01B 1/127 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/48 (20130101) H01G 11/56 (20130101) H01G 11/84 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867757 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Clark T.-C. Nguyen (Oakland, California); Ruonan Liu (Berkeley, California); Jalal Naghsh Nilchi (Berkeley, California) |
| ABSTRACT | A microelectromechanical resonant switch (“resoswitch”) converts received radio frequency (RF) energy into a clock output. The resoswitch first accepts incoming amplitude- or frequency-shift keyed clock-modulated RF energy at a carrier frequency, filters it, provides power gain via resonant impact switching, and finally envelop detects impact impulses to demodulate and recover the carrier clock waveform. The resulting output derives from the clock signal that originally modulated the RF carrier, resulting in a local clock that shares its originator's accuracy. A bare push-pull 1-kHz RF-powered mechanical clock generator driving an on-chip inverter gate capacitance of 5 fF can potentially operate with only 5 pW of battery power, 200,000 times lower than a typical real-time clock. Using an off-chip inverter with 17.5 pF of effective capacitance, a 1-kHz push-pull resonator would consume 17.5 nW. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/167799 |
| ART UNIT | 2849 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 1/0036 (20130101) Original (OR) Class H01H 2001/0078 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/462 (20130101) H03H 9/505 (20130101) H03H 9/2426 (20130101) Pulse Technique H03K 3/01 (20130101) H03K 5/135 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867781 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); William McKay Gilliland, Jr. (Chapel Hill, North Carolina) |
| ABSTRACT | An electrospray ionization (ESI)-mass spectrometer analysis systems include an ESI device with at least one emitter configured to electrospray ions and a mass spectrometer in fluid communication with the at least one emitter of the ESI device. The mass spectrometer includes a mass analyzer held in a vacuum chamber. The vacuum chamber is configured to have a high (background/gas) pressure of about 50 mTorr or greater during operation. During operation, the ESI device is configured to either; (a) electrospray ions into a spatial region external to the vacuum chamber and at atmospheric pressure, the spatial extent being adjacent to an inlet device attached to the vacuum chamber, the inlet device intakes the electrosprayed ions external to the vacuum chamber with the mass analyzer and discharges the ions into the vacuum chamber with the mass analyzer; or (b) electrospray ions directly into the vacuum chamber with the mass analyzer. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/371213 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/24 (20130101) H01J 49/0031 (20130101) H01J 49/165 (20130101) Original (OR) Class H01J 49/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867887 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Evelyn Wang (Cambridge, Massachusetts); Yangying Zhu (Cambridge, Massachusetts); Kuang-Han Chu (Chandler, Arizona); Dion Savio Antao (Somerville, Massachusetts) |
| ABSTRACT | A two-phase microchannel heat sink can be a fluid channel including a bottom wall including a superhydrophilic surface with microstructures and a side wall including a surface that is hydrophobic relative to the superhydrophilic surface of the bottom wall. When heat flux is applied to the fluid channel, a liquid film on the bottom wall is maintained and nucleation of boiling occurs only on the side wall. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 14/811811 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/187 (20130101) F28F 2245/02 (20130101) F28F 2245/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) Original (OR) Class H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867914 | Dardona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Sameh Dardona (South Windsor, Connecticut); Dustin D. Caldwell (Portland, Connecticut); Callum Bailey (Glastonbury, Connecticut) |
| ABSTRACT | An extendable sensor system having a lattice topology includes a number of extendable interconnects having one or more electrically-conductive layers alternately sandwiched between two or more dielectric layers, two or more interconnect nodes, each located on the lattice topology and electrically-connected to the extendable interconnects to define a sensor array topology, and one or more sensors. The extendable interconnects are arranged in a serpentine pattern that is configured to be expanded, thereby extending the extendable sensor system. The expanded interconnects define an extended sensor system topology, and is configured to be installed on the surface of an asset. Methods of manufacturing an extendable sensor system are also disclosed. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/299502 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76895 (20130101) H01L 23/528 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868191 | Park |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Jisung Park (Ithaca, New York) |
| ABSTRACT | Patterning electronic devices using reactive-ion etching of tin oxides is provided. Reactive-ion etching facilitates patterning of tin oxides, such as barium stannate (BaSnO3), at a consistent and controllable etch rate. The reactive-ion etching approach described herein facilitates photolithographic patterning of tin oxide-based semiconductors to produce electronic devices, such as thin-film transistors (TFTs). This approach further patterns a tin oxide-based semiconductor without adversely affecting its electrical properties (e.g., resistivity, electron or hole mobility), as well as maintaining surface roughness. This approach can be used to produce optically transparent devices with high drain current (ID, drain-to-source current per channel width) and high on-off ratio. |
| FILED | Friday, December 06, 2019 |
| APPL NO | 16/706122 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 19/02 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/4682 (20130101) C04B 2235/3293 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/31144 (20130101) H01L 29/24 (20130101) H01L 29/45 (20130101) H01L 29/517 (20130101) H01L 29/4966 (20130101) H01L 29/7869 (20130101) Original (OR) Class H01L 51/0018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868320 | Gould et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Benjamin D. Gould (Alexandria, Virginia); Joseph Rodgers (Jessup, Maryland); Richard Stroman (Washington, District of Columbia); Matthew Hazard (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin D. Gould (Alexandria, Virginia); Joseph Rodgers (Jessup, Maryland); Richard Stroman (Washington, District of Columbia); Matthew Hazard (Washington, District of Columbia) |
| ABSTRACT | A fuel cell includes a catalyst coated membrane with a proton exchange membrane, a cathode layer disposed on a first surface of the proton exchange membrane, and an anode layer disposed on an oppositely disposed second surface of the proton exchange membrane. At least one gas diffusion layer is bonded to at least one of the cathode and anode layers of the catalyst coated membrane. At least one bonding layer substantially surrounds at least one of the catalyst coated membrane and the at least one gas diffusion layer. The at least one bonding layer is bonded to a portion of the proton exchange membrane. At least one circuit is bonded to a portion of the gas diffusion layer and a portion of the at least one bonding layer. |
| FILED | Tuesday, September 22, 2015 |
| APPL NO | 14/861809 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0269 (20130101) H01M 8/1004 (20130101) Original (OR) Class H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868540 | Herr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anna Y. Herr (Ellicott City, Maryland); Quentin P. Herr (Ellicott City, Maryland); Ryan Edward Clarke (Hanover, Maryland); Harold Clifton Hearne, III (Baltimore, Maryland); Alexander Louis Braun (Baltimore, Maryland); Randall M. Burnett (Catonsbille, Maryland); Timothy Chi-Chao Lee (Gaithersburg, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Anna Y. Herr (Ellicott City, Maryland); Quentin P. Herr (Ellicott City, Maryland); Ryan Edward Clarke (Hanover, Maryland); Harold Clifton Hearne, III (Baltimore, Maryland); Alexander Louis Braun (Baltimore, Maryland); Randall M. Burnett (Catonsbille, Maryland); Timothy Chi-Chao Lee (Gaithersburg, Maryland) |
| ABSTRACT | Non-destructive read out (NDRO) circuits are provided for use in reciprocal quantum logic (RQL) superconducting systems. Each NDRO circuit includes a “body” circuit that provides a single or multi-state sub-critical bias current to one or many independent “tail” circuitries. Each “tail” has minimal effect on the “body” thereby preventing any interference or destruction to the state of the “body” circuitry. The circuits reduce device count and thereby increase circuit density, simplify and reduce the cost of fabrication, and provide functionality not available in existing designs, such as the ability to write a state and read it in the same operation cycle. The NDRO circuits provide more compact unit cells useful in memory or logic arrays, demanding fewer resources with increased functionality. The circuits also provide compact cells for AND, AND-OR, A-NOT-B, inverter, multiplexer, and demultiplexer gates. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700615 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 11/44 (20130101) Pulse Technique H03K 3/38 (20130101) H03K 19/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868576 | Gong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Songbin Gong (Champaign, Illinois); Ruochen Lu (Champaign, Illinois); John Andrew Krol (Manhattan, Illinois); Liuqing Gao (Champaign, Illinois) |
| ABSTRACT | An apparatus includes parallel delay lines, each exhibiting a delay; a first set of switches for each port of a first set of ports, each of which is to selectively couple a port of the first set of ports to first ends of the delay lines; a second set of switches for each port of a second set of ports, each of which to selectively couple a port of the second set of ports to second ends of the delay lines. A signal source generates a series of clock signals that are sequentially time delayed between the first set of switches and the second set of switches, where an input signal at one of the first or second sets of ports travels from the one of the first or second sets of ports to an output port of opposite set of ports over the delay lines. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/396024 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/387 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/74 (20130101) Pulse Technique H03K 5/14 (20130101) H03K 5/135 (20130101) H03K 2005/00078 (20130101) Transmission H04B 1/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868825 | Dominessy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Christopher Dominessy (Painted Post, New York); Scott Aloisio (Ithaca, New York); Robert A. Joyce (Ithaca, New York) |
| ABSTRACT | An example network security and threat assessment system is configured to determine, based on one or more events that have occurred during execution of one or more applications, a potential security vulnerability of a target computing system, where the one or more events correspond to a node represented in the hierarchical risk model. The system is further configured to identify, based on a mapping of the node represented in the hierarchical risk model to a node represented in a hierarchical game tree model, one or more actions that are associated with the potential security vulnerability and that correspond to the node represented in the hierarchical game tree model, and to output, for display in a graphical user interface, a graphical representation of the potential security vulnerability and the one or more actions associated with the potential security vulnerability. |
| FILED | Friday, September 14, 2018 |
| APPL NO | 16/131669 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/06 (20130101) H04L 43/045 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868843 | Ethier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Randall Paul Joseph Ethier (Burke, Virginia); Gene Lee Harrison (Leesburg, Virginia) |
| ABSTRACT | Disclosed herein are system, apparatus, method and/or computer program product embodiments for providing survivable calling and conferencing. An embodiment operates by providing, by a first server, a first sub-conference to a plurality of user devices over first lines. The first sub-conference is combined with a second sub-conference to form a collective conference of the plurality of user devices. The first server accesses the conference. A second server is configured to provide the second sub-conference of the collective conference to the plurality of user devices over second lines, the first and second lines being distinct from each other. The collective conference may provide resilient and reliable sharing of information among participants and may leverage dispersed elements or diverse links simultaneously without impediments of echoes, loops, or other impacts. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 16/420995 |
| ART UNIT | 2454 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 65/80 (20130101) H04L 65/403 (20130101) Original (OR) Class H04L 65/1073 (20130101) H04L 65/1096 (20130101) H04L 65/4076 (20130101) H04L 67/10 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10864501 | Siriwardane |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Ranjani V. Siriwardane (Morgantown, West Virginia) |
| ABSTRACT | The invention provides a use of metal ferrite oxygen carrier for converting carbon dioxide to carbon monoxide or synthesis gas via three processes: catalytic dry reforming of methane, chemical looping dry reforming of fuel and promoting coal gasification with CO2. The metal ferrite oxygen carrier comprises MzFexOy, where MzFexOy is a chemical composition with 0<x≤4, z>0 and 0<y≤6 and M is one of Ca, Ba, and/or combinations thereof. For example, MzFexOy may be one of CaFe2O4, BaFe2O4, MgFe2O4, SrFe2O4 and/or combinations thereof. In catalytic dry reforming, methane and carbon dioxide react in the presence of metal ferrites generating a product stream comprising at least 50 vol. % CO and H2. In another embodiment, chemical looping dry reforming process where metal ferrite is reduced with a fuel and then oxidized with carbon dioxide is used for production of CO from carbon dioxide. In another embodiment, the metal ferrite is used as a promoter to produce CO continuously from coal gasification with CO2. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/550747 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/78 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 2203/066 (20130101) C01B 2203/0238 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864578 | Barr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Christian Barr (Kansas City, Missouri); Wesley Everhart (Overland Park, Kansas) |
| ABSTRACT | A computing device for controlling the operation of an additive manufacturing machine comprises a memory element and a processing element. The memory element is configured to store a three-dimensional model of a part to be manufactured, wherein the three-dimensional model defines a plurality of cross sections of the part. The processing element is in communication with the memory element. The processing element is configured to receive the three-dimensional model, determine a plurality of paths, each path including a plurality of parallel lines, determine a radiation beam power for each line, such that the radiation beam power varies non-linearly according to a length of the line, and determine a radiation beam scan speed for each line, such that the radiation beam scan speed is a function of a temperature of a material used to manufacture the part, the length of the line, and the radiation beam power for the line. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885214 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/003 (20130101) B22F 3/1055 (20130101) Original (OR) Class B22F 2003/1056 (20130101) B22F 2003/1057 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864618 | Schnitzler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joshua Michael Schnitzler (Kansas City, Missouri); Donald Conrad Branson (Kansas City, Missouri) |
| ABSTRACT | A driver for non-magnetic gripping of a socketed fastener head. The driver includes a shank and two cantilever beams. Each cantilever beam has an end and a basal segment adjacent the shank opposite the end. The driver also includes a gap defined by the two cantilever beams in resting positions. The gap extends between the two cantilever beams from an open end toward the shank. The ends of the two cantilever beams are configured to bend into the gap from the resting positions. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615639 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 15/004 (20130101) Original (OR) Class B25B 23/105 (20130101) Handles for Hand Implements B25G 3/28 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 23/0007 (20130101) F16B 23/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864673 | Fenn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David Robert Fenn (Allison Park, Pennsylvania); Kurt G. Olson (Gibsonia, Pennsylvania); Reza M. Rock (Pittsburgh, Pennsylvania); Cynthia Kutchko (Allison Park, Pennsylvania); Susan Donaldson (Allison Park, Pennsylvania); Anthony J. Fogl (Swissvale, Pennsylvania) |
| ABSTRACT | Methods of additive manufacture using coreactive components are disclosed. Thermosetting compositions for additive manufacturing are also disclosed. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/423474 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/325 (20130101) C08G 18/755 (20130101) C08G 18/792 (20130101) C08G 18/3234 (20130101) C08G 18/3821 (20130101) C08G 18/3855 (20130101) C08G 18/4854 (20130101) C08G 18/5024 (20130101) C08G 18/6685 (20130101) C08G 59/66 (20130101) C08G 75/14 (20130101) C08G 75/045 (20130101) C08G 2150/50 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/046 (20170501) C08K 3/046 (20170501) Compositions of Macromolecular Compounds C08L 75/02 (20130101) C08L 81/02 (20130101) C08L 81/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/02 (20130101) C09D 175/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865136 | Simpson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Lin Jay Simpson (Lakewood, Colorado); Chaiwat Engtrakul (Louisville, Colorado) |
| ABSTRACT | Transparent and insulating materials having evacuated capsules are provided. According to an aspect of the invention, a method includes forming evacuated capsules within a solution, and dispersing and suspending the evacuated capsules within the solution such that a packing density of the evacuated capsules within the solution is greater than 30%, and a visible light transmission of the solution including the evacuated capsules is greater than 75%. According to another aspect of the invention, a layer includes a plurality of evacuated capsules distributed within a dried sol-gel. A thermal conductivity of the layer is between 0.02 W/m-K and 0.001 W/m-K, and the layer has a visible light transmission of greater than 30%. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 15/656378 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/32 (20130101) C01P 2004/34 (20130101) C01P 2004/84 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 19/107 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 11/002 (20130101) Original (OR) Class C03C 17/2453 (20130101) C03C 2217/211 (20130101) C03C 2217/216 (20130101) C03C 2218/15 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 7/28 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249974 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865216 | Bensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MERCK SHARP and DOHME CORP. (Rahway, New Jersey); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | MERCK SHARP and DOHME CORP. (Rahway, New Jersey); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Daniel Bensen (Carlsbad, California); Allen Borchardt (San Diego, California); Zhiyong Chen (San Diego, California); John M. Finn (Encinitas, California); Thanh To Lam (San Diego, California); Suk Joong Lee (San Diego, California); Xiaoming Li (San Diego, California); Leslie William Tari (San Diego, California); Min Teng (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Michael E. Jung (Los Angeles, California); Felice C. Lightstone (Fremont, California); Sergio E. Wong (San Jose, California); Toan B. Nguyen (San Ramon, California) |
| ABSTRACT | Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. In addition, species of tricyclic gyrase inhibitors compounds are also disclosed herein. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated. |
| FILED | Wednesday, September 11, 2013 |
| APPL NO | 14/427611 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) C07D 487/16 (20130101) C07D 487/22 (20130101) C07D 498/22 (20130101) C07D 515/22 (20130101) C07D 519/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865421 | Cahoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (O'Fallon, Missouri) |
| ABSTRACT | Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385688 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865422 | Schnell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Danny J. Schnell (Belchertown, Massachusetts); Mine O. Canakci (Granby, Massachusetts); Bibin Paulose (Amherst, Massachusetts); Michelle DaCosta Inguagiato (Wilbraham, Massachusetts) |
| ABSTRACT | A transgenic plant having enhanced photosynthesis is disclosed. The transgenic plant is transformed with a transgenic polynucleotide encoding a heterologous bicarbonate transporter. The bicarbonate transporter can be from an algae or a cyanobacterial species. The transgenic polynucleotide comprises a nucleic acid sequence encoding the bicarbonate transporter under the control of a functional plant promoter and optionally includes a chloroplast envelope targeting peptide heterologous to the bicarbonate transporter. Methods of making the transgenic plant and transgenic polynucleotide are disclosed. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/421599 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8245 (20130101) C12N 15/8247 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865746 | Warlick, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ACHATES POWER, INC. (San Diego, California) |
| ASSIGNEE(S) | Achates Power, Inc. (San Diego, California) |
| INVENTOR(S) | Richard D. Warlick, Jr. (Farmington Hills, Michigan); Cain Piotrowski (Farmington Hills, Michigan) |
| ABSTRACT | An opposed-piston engine is configured to fit in an engine compartment of a light-duty truck without compromising engine operations or the integrity of the engine compartment. The opposed-piston engine includes an air handling system and can be configured so that a cylinder assembly of the engine is tilted. The tilt of the cylinder assembly can allow for all of the components of the engine's air handling system to be located on one side of the opposed-piston engine. The air handling system of the opposed-piston engine can be configured with a cobra-head shaped intake duct assembly. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414082 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 5/02 (20130101) B60K 17/04 (20130101) Motor Vehicles; Trailers B62D 21/02 (20130101) B62D 25/081 (20130101) B62D 25/082 (20130101) B62D 25/105 (20130101) B62D 33/02 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/41 (20160201) F02M 26/42 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866263 | Montazeri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Arthur Okhtay Montazeri (Berkeley, California); Hoi-Ying N. Holman (Oakland, California); Stefano Cabrini (Albany, California) |
| ABSTRACT | Plasmonic gratings, along with methods of creating devices using width-graded plasmonic gratings are described. Plasmonic gratings may be transmission-type or closed-ended plasmonic gratings, and may be disposed on detectors to enhance the spectral range detection of the detectors or in further device architectures. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/152204 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/554 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/22 (20130101) G01Q 60/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867079 | Hart |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Mark Miles Hart (Livermore, California) |
| ABSTRACT | An Initialization Unit (IU) initiates an initial secure connection with an Intrinsic Use Control (IUC) Chip based on very large random numbers (VLRNs). The IUC Chip in turn initiates a secondary secure connection between it and one or more Use Controlled Components (UCCs). Polling by the IU allows confirmation of an ongoing secure connection, and also allows the IUC Chip to confirm the secondary secure connection to the UCCs. Removal or improper polling response from one of the UCCs results in a response from the IUC Chip that may include notification of tampering, or temporary or permanent discontinued operation of the offending UCC. Permanent discontinued operation may include destruction of the offending UCC, and cascaded discontinued operation of all other UCCs secured by the IUC Chip. A UCC may in turn be another nested layer of IUC Chips, controlling a corresponding layer of UCCs, ad infinitum. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/034080 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/57 (20130101) G06F 21/88 (20130101) Original (OR) Class G06F 2221/2141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867415 | Korbin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | John P. Korbin (Albuquerque, New Mexico); David Peterson (Albuquerque, New Mexico); Matthew David Smith (Albuquerque, New Mexico); Carianne Martinez (Albuquerque, New Mexico); Charles Snider (Albuquerque, New Mexico); Kevin M. Potter (Rio Rancho, New Mexico) |
| ABSTRACT | Constructing a computer image from raw imaging data or encoded imaging data by transforming a first data structure in which the raw imaging data or the encoded imaging data is stored into a second data structure storing reorganized imaging data. The raw imaging data or the encoded imaging data is received, stored in the first data structure. The computer reorganizes the raw imaging data or the encoded imaging data into the reorganized data and stores the reorganized data in the second data structure, which is a multi-dimensional array having subarrays containing local information needed by a convolutional neural network for processing the reorganized data. Other portions of the multi-dimensional array store other portions of the raw imaging data or the encoded imaging data. The computer also processes the reorganized data using the convolutional neural network to construct the image, whereby a constructed image is formed. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/250910 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) Image Data Processing or Generation, in General G06T 1/60 (20130101) G06T 9/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867715 | Woloshun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Keith A. Woloshun (Los Alamos, New Mexico); Eric R. Olivas (Los Alamos, New Mexico); Gregory E. Dale (Los Alamos, New Mexico) |
| ABSTRACT | Apparatus for radioisotope production includes housing, a plurality of target disks inside the housing and a curved windows positioned convex inward toward the disks. During operation, coolant flows though the housing across the disks and windows while electron beams passes through the window and the disks. The window temperature increases, rising the fastest in the middle of the window where the electron beam hits the window. A flat window would buckle because the center would deform during thermal expansion against the relatively unaffected periphery, but the curved window shape allows the window to endure high thermal and mechanical stress created by a combination of heating from the electron beam(s) and elevated pressure from coolant on the inside of the window. Such a window may be used for applications in which a pressurized coolant acts on only one side of the window. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 15/526699 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) Original (OR) Class G21G 1/10 (20130101) G21G 2001/0036 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) H05H 2006/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867730 | Matthiesen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | David Matthiesen (Cleveland, Ohio) |
| ABSTRACT | A process for producing an ordered martensitic iron nitride powder that is suitable for use as a permanent magnetic material is provided. The process includes fabricating an iron alloy powder having a desired composition and uniformity; nitriding the iron alloy powder by contacting the material with a nitrogen source in a fluidized bed reactor to produce a nitride iron powder; transforming the nitride iron powder to a disordered martensitic phase; annealing the disordered martensitic phase to an ordered martensitic phase; and separating the ordered martensitic phase from the iron nitride powder to yield an ordered martensitic iron nitride powder. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 15/974517 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 9/082 (20130101) B22F 2009/041 (20130101) B22F 2009/043 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/0622 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2006/42 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/6265 (20130101) C04B 35/6268 (20130101) C04B 35/58042 (20130101) C04B 35/62615 (20130101) C04B 2235/46 (20130101) C04B 2235/81 (20130101) C04B 2235/404 (20130101) C04B 2235/405 (20130101) C04B 2235/465 (20130101) C04B 2235/5436 (20130101) Alloys C22C 33/0264 (20130101) C22C 2202/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/26 (20130101) C23C 8/62 (20130101) C23C 8/80 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/08 (20130101) H01F 1/24 (20130101) Original (OR) Class H01F 1/065 (20130101) H01F 1/083 (20130101) H01F 41/0266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867768 | Mane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | An enhanced electron amplifier structure includes a microporous substrate having a front surface and a rear surface, the microporous substrate including at least one channel extending substantially through the substrate between the front surface and the rear surface, an ion diffusion layer formed on a surface of the channel, the ion diffusion layer comprising a metal oxide, a resistive coating layer formed on the first ion diffusion layer, an emissive coating layer formed on the resistive coating layer, and an optional ion feedback layer formed on the front surface of the structure. The emissive coating produces a secondary electron emission responsive to an interaction with a particle received by the channel. The ion diffusion layer, the resistive coating layer, the emissive coating layer, and the ion feedback layer are independently deposited via chemical vapor deposition or atomic layer deposition. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/691633 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 1/32 (20130101) Original (OR) Class H01J 9/125 (20130101) H01J 43/04 (20130101) H01J 43/246 (20130101) H01J 2209/012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868293 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | POLYPLUS BATTERY COMPANY (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Richard L. Swisher (Northfield, Minnesota) |
| ABSTRACT | Methods for making solid-state laminate electrode assemblies include methods of forming a solid electrolyte interphase (SEI) by ion implanting nitrogen and/or phosphorous into the glass surface by ion implantation. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/663177 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/3626 (20130101) C03C 17/3649 (20130101) C03C 17/3671 (20130101) C03C 2218/151 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/24 (20130101) C23C 14/34 (20130101) C23C 14/48 (20130101) C23C 14/0641 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/0407 (20130101) H01M 4/0423 (20130101) Original (OR) Class H01M 4/628 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868333 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chi Cheung Su (Westmont, Illinois); Khalil Amine (Oakbrook, Illinois); Meinan He (Sterling Heights, Michigan) |
| ABSTRACT | An electrochemical cell includes a cathode active material, lithium metal, a separator, and an electrolyte including a lithium salt and a fluorinated glycol ether. |
| FILED | Wednesday, January 23, 2019 |
| APPL NO | 16/255621 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0565 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 12/08 (20130101) H01M 2300/0025 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868335 | Lau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Ka-Cheong Lau (Chicago, Illinois); Chen Liao (Westmont, Illinois) |
| ABSTRACT | Magnesium salts suitable for use in an electrolyte for a magnesium ion electrochemical cell are described herein. The salts are magnesium tetra(perfluoroalkoxy)metalates, optionally solvated with up to seven ether molecules coordinated to the magnesium ion thereof. In one embodiment, the salt has the empirical formula: Mg(Z)n2+[M(OCR3)4−]2 (Formula (I)) wherein Z is an ether; n is 0 to about 7; M is Al or B; and each R independently is a perfluoroalkyl group (e.g., C1 to C10 perfluoroalkyl). The magnesium salts of Formula (I) are suitable for use as electrolyte salts for magnesium ion batteries (e.g., 5 V class magnesium batteries) and exhibit a wide redox window that is particularly compatible with magnesium anode. The salts are relatively cost effective to prepare by methods described herein, which are conveniently scalable to levels suitable for commercial production. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/133278 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) C07F 5/069 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/054 (20130101) H01M 10/0568 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10864091 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tyagi Ramakrishnan (White Rock, New Mexico); Kyle B. Reed (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Tyagi Ramakrishnan (White Rock, New Mexico); Kyle B. Reed (Tampa, Florida) |
| ABSTRACT | A prosthetic knee having a passive knee locking mechanism that uses the same four-bar mechanics found in a natural knee. The flexible four-bar mechanism guides the motion of the knee, aids in the return of the knee from full flexion to extension, and connects a femoral gear to a tibial gear. The gears have a circular radius and are connected using parallel links to keep the femur and tibia together when the knee is active. The knee stays locked throughout the stance phase. At toe off, no weight is applied on the prosthetic knee allowing the knee to flex. The flexible links are stretched, thereby increasing the stiffness in the springs, and at terminal swing phase, moments before heel strike, the flexible links in the four-bar mechanism snap back to the extended/locking position and lockout once the user applies his/her weight on the knee. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 16/401886 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/642 (20130101) A61F 2/644 (20130101) Original (OR) Class A61F 2002/503 (20130101) A61F 2002/5007 (20130101) A61F 2002/5009 (20130101) A61F 2002/5043 (20130101) A61F 2002/5073 (20130101) A61F 2002/6836 (20130101) A61F 2002/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864170 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Jung Seok Lee (New Haven, Connecticut); Dongin Kim (Glastonbury, Connecticut) |
| ABSTRACT | Pharmaceutical composition containing poly(bile) acid (PBA) polymers for oral delivery of agent(s) show enhanced uptake by the pancreas, liver, and colon. These nanoparticles show significant retention in the pancreas and colon and are therefore useful for selective delivery. The examples demonstrate efficacy of oral administration of insulin to treat diabetes, and oral induction of tolerance by administration of insulin or ovalbumin in combination with rapamycin. Diabetic animals treated with the insulin or insulin with rapamycin showed normalization of blood glucose levels. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/757608 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 9/5153 (20130101) A61K 31/436 (20130101) A61K 38/28 (20130101) A61K 45/00 (20130101) A61K 47/6935 (20170801) A61K 49/1824 (20130101) A61K 51/1244 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 1/18 (20180101) A61P 3/10 (20180101) A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864273 | Crespo-Hernandez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Carlos E. Crespo-Hernandez (Cleveland, Ohio); Marvin Pollum (Cleveland, Ohio) |
| ABSTRACT | A method of using a compound in a phototherapy procedure includes administering to a subject in need of treatment a therapeutically effective amount of a thio-substituted nucleobase, nucleoside, nucleotide, and/or analogs thereof; and exposing the administered compound to electromagnetic radiation. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/573682 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0659 (20130101) A61N 2005/0661 (20130101) A61N 2005/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864303 | Bettinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher J. Bettinger (Palo Alto, California); Joost P. Bruggeman (Schorl, Netherlands); Lino da Silva Ferreira (Coimbra, Portugal); Jeffrey M. Karp (Brookline, Massachusetts); Robert S. Langer (Newton, Massachusetts); Christiaan Nijst (Amsterdam, Netherlands); Andreas Zumbuehl (Nyon, Switzerland); Jason Burdick (Philadelphia, Pennsylvania); Sonia J. Kim (West Nyack, New York) |
| ABSTRACT | The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206937 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/48 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/58 (20130101) A61L 31/06 (20130101) Original (OR) Class A61L 31/148 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/6854 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/246 (20130101) C08J 2367/00 (20130101) C08J 2367/07 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/0025 (20130101) Compositions of Macromolecular Compounds C08L 67/00 (20130101) C08L 67/07 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10864577 | Hopkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Uniformity Labs, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Uniformity Labs Inc. (Menlo Park, California) |
| INVENTOR(S) | Adam Bayne Hopkins (San Jose, California); Salvatore Torquato (Princeton, New Jersey) |
| ABSTRACT | The present invention relates to granular composite density enhancement, and related methods and compositions. The application where these properties are valuable include but are not limited to: 1) additive manufacturing (“3D printing”) involving metallic, ceramic, cermet, polymer, plastic, or other dry or solvent-suspended powders or gels, 2) concrete materials, 3) solid propellant materials, 4) cermet materials, 5) granular armors, 6) glass-metal and glass-plastic mixtures, and 7) ceramics comprising (or manufactured using) granular composites. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/235654 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0014 (20130101) Original (OR) Class B22F 1/0048 (20130101) B22F 3/11 (20130101) B22F 3/1055 (20130101) B22F 3/1055 (20130101) B22F 7/002 (20130101) B22F 7/02 (20130101) B22F 7/008 (20130101) B22F 2202/01 (20130101) B22F 2301/15 (20130101) B22F 2301/35 (20130101) B22F 2301/205 (20130101) B22F 2302/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) B23K 26/354 (20151001) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 64/153 (20170801) B29C 64/165 (20170801) B29C 64/268 (20170801) B29C 64/371 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0064 (20130101) B29K 2105/251 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 70/00 (20141201) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 12/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 14/06 (20130101) C04B 14/048 (20130101) C04B 20/0076 (20130101) C04B 20/0096 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 35/56 (20130101) C04B 35/111 (20130101) C04B 35/547 (20130101) C04B 35/5626 (20130101) C04B 35/62695 (20130101) C04B 2235/405 (20130101) C04B 2235/446 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3847 (20130101) C04B 2235/5427 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5472 (20130101) Alloys C22C 1/08 (20130101) C22C 1/0458 (20130101) C22C 14/00 (20130101) C22C 29/08 (20130101) C22C 32/0052 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/44 (20130101) C22C 38/56 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865421 | Cahoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (O'Fallon, Missouri) |
| ABSTRACT | Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385688 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866184 | Ismagilov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Jesus Rodriguez Manzano (London, United Kingdom); Mikhail Karymov (San Jose, Canada); David A. Selck (Sterling, Virginia); Stefano Begolo (Inglewood, California); Erik B. Jue (Moorpark, California); Dmitriy V. Zhukov (Pasadena, California) |
| ABSTRACT | The present invention relates to methods, computer readable medium and systems for detecting and counting single nucleic acid molecules confined in nanoliter volumes using an unmodified camera, such as a cell phone camera. In particular, it identifies colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones. The invention further provides an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/774004 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2527/101 (20130101) C12Q 2537/165 (20130101) C12Q 2563/159 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/46 (20130101) G01J 3/50 (20130101) G01J 3/0272 (20130101) G01J 3/463 (20130101) G01J 2003/468 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/253 (20130101) Original (OR) Class G01N 2201/0221 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 7/90 (20170101) G06T 2207/10012 (20130101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866229 | Meng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Huaiyu Meng (Medford, Massachusetts); Rajeev Ram (Arlington, Massachusetts) |
| ABSTRACT | A system for molecular mapping includes a semiconductor substrate defining a reservoir to receive a sample of molecules and a nanofluidic channel in fluid communication with the reservoir. The system also includes a plurality of electrodes, in electrical communication with the nanofluidic channel, to electrophoretically trap the sample of molecules in the nanofluidic channel. At least one avalanche photodiode is fabricated in the semiconductor substrate and disposed within an optical near-field of the nanofluidic channel to detect fluorescence emission from at least one molecule in the sample of molecules. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883183 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0816 (20130101) B01L 2300/0896 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) B81B 2203/0338 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00246 (20130101) B81C 2203/0742 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/001 (20130101) B82B 3/0019 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 40/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44713 (20130101) G01N 27/44726 (20130101) G01N 27/44791 (20130101) G01N 33/48707 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/107 (20130101) H01L 31/165 (20130101) H01L 31/02005 (20130101) H01L 31/02019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10866992 | Pol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gratiana Denisa Pol (Los Angeles, California); Gilbert Jude Calvillo (San Rafael, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gratiana Denisa Pol (Los Angeles, California); Gilbert Jude Calvillo (San Rafael, California) |
| ABSTRACT | A system and method for extracting, searching, visualizing, and navigating scientific, technical and academic research and literature using constructs and causal relationships between such constructs, the relationships including independent variables, dependent variables, mediator variables, moderator variables, and covariate control variables. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595942 |
| ART UNIT | 2156 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/34 (20190101) G06F 16/93 (20190101) Original (OR) Class G06F 16/313 (20190101) G06F 16/355 (20190101) G06F 16/367 (20190101) G06F 16/3331 (20190101) G06F 16/3344 (20190101) G06F 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10867937 | Rajendran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); The Texas A and M University System (College Station, Texas); Nankai University (Nankai Qu, China PRC) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jeyavijayan Rajendran (Dallas, Texas); Jiang Hu (College Station, Texas); Yujie Wang (Tianjin, China PRC); Pu Chen (Seattle, Washington) |
| ABSTRACT | Disclosed are various embodiments to enhance the security of a circuit design after a global routing of the circuit design and an assignment of wire layers for the circuit design. A tree can be extracted from the circuit design. The tree can include multiple gates and location information for the gates. The tree can be perturbed by moving one or more locations of one or more gates. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 15/987309 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/505 (20130101) G06F 17/5022 (20130101) G06F 17/5068 (20130101) G06F 17/5072 (20130101) G06F 17/5077 (20130101) G06F 17/5081 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/573 (20130101) Original (OR) Class H01L 23/576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10864281 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Joseph D. Donovan (Urbana, Illinois); Soo-Yeun Lee (Champaign, Illinois); Youngsoo Lee (Champaign, Illinois) |
| ABSTRACT | The invention provides novel formulations comprising a stable inclusion complex of tributyrin and a cyclodextrin. In one particular embodiment, the formulation comprises an oven dried inclusion complex of tributyrin and γ-cyclodextrin that is effective in minimizing or preventing the unpleasant taste and odor of tributyrin, thus making it suitable for oral administration and delivery to the digestive tract and intestines. The invention provides compositions of these inclusion complexes and methods of using them that are advantageous as food, medicinal and other products, where the negative sensory properties of tributyrin can be a liability. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/145416 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/12 (20160801) A23L 33/15 (20160801) A23L 33/16 (20160801) A23L 33/17 (20160801) A23L 33/40 (20160801) A23L 33/155 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/32 (20130101) A23V 2250/1946 (20130101) A23V 2250/5112 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/07 (20130101) A61K 31/07 (20130101) A61K 31/25 (20130101) A61K 31/25 (20130101) A61K 31/225 (20130101) A61K 31/355 (20130101) A61K 31/355 (20130101) A61K 31/593 (20130101) A61K 31/593 (20130101) A61K 45/06 (20130101) A61K 47/6949 (20170801) Original (OR) Class A61K 47/6951 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865419 | Daniell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Henry Daniell (Philadelphia, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts. |
| FILED | Wednesday, October 24, 2012 |
| APPL NO | 14/353980 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) A61K 38/51 (20130101) A61K 38/162 (20130101) A61K 38/164 (20130101) A61K 38/2278 (20130101) Peptides C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865421 | Cahoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Edgar Cahoon (Lincoln, Nebraska); Umidjon Iskandarov (Lincoln, Nebraska); Hae Jin Kim (Lincoln, Nebraska); Jillian Collins-Silva (O'Fallon, Missouri) |
| ABSTRACT | Provided herein are novel acyltransferases and methods of using such novel acyltransferases in making medium-chain fatty acids. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385688 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP32617 | Scorza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Ralph Scorza (Shepherdstown, West Virginia); Mark Demuth (Kearneysville, West Virginia) |
| ABSTRACT | A new hardy kiwi is of the variety denominated ‘Tango’ Actinidia chinensis Planch, originated from open pollination of A. chinensis selections collected in Rome. This new kiwi can be distinguished by its cold hardiness, high fruit quality, and relatively large fruit size. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 16/501886 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/00 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP32645 | Kenworthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| INVENTOR(S) | Kevin E. Kenworthy (Gainesville, Florida); Kenneth H. Quesenberry (Gainesville, Florida) |
| ABSTRACT | ‘FSA1602’ is a new and distinct St. Augustine grass (Stenotaphrum secundatum (Walt.) Kuntze) variety distinguished at least by its distinctive olive blue-green color, large stolon size, and good tolerance to leaf diseases. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/501837 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/46 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10865306 | Esser-Kahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Aaron P. Esser-Kahn (Champaign, Illinois); Hefei Dong (Urbana, Illinois); Piyush R. Thakre (Lake Jackson, Texas); Jason F. Patrick (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois) |
| ABSTRACT | A microvascular system includes a solid polymeric matrix and a woven structure in the matrix. The woven structure includes a plurality of fibers, and a plurality of microfluidic channels, where at least a portion of the microfluidic channels are interconnected. The microvascular system may be made by forming a composite that includes a solid polymeric matrix and a plurality of sacrificial fibers in the matrix, heating the composite to a temperature of from 100 to 250° C., maintaining the composite at a temperature of from 100 to 250° C. for a time sufficient to form degradants from the sacrificial fibers, and removing the degradants from the composite. The sacrificial fibers may include a polymeric fiber matrix including a poly(hydroxyalkanoate) and a metal selected from the group consisting of an alkali earth metal and a transition metal, in the fiber matrix, where the concentration of the metal in the fiber matrix is at least 0.1 wt %. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 15/960076 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/023 (20190201) B29C 67/202 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/20 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/04 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2958 (20150115) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10865389 | Puckette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Puckette (Waterford, Connecticut); Max V. Rasmussen (Guilford, Connecticut) |
| ABSTRACT | This application is directed generally to foot-and-mouth disease virus (FMDV) 3C proteases that have been modified by mutating a polynucleotide sequence coding for the FMDV 3C protease. The modified FMDV proteases exhibit proteolytic activity on FMDV P1 precursor protein and exhibit a reduction in one or more toxic or inhibitory properties associated with an unmodified FMDV 3C protease on a host cell used to recombinantly produce it. Vectors carrying polynucleotides encoding modified FMDV 3C protease sequences can induce production of FMDV virus-like particles in a host cell when expressed in the host cell. The modified FMDV 3C proteases can generally be used to produce immunogenic FMDV preparations capable of inducing an immune response against FMDV. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369177 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/135 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 16/1009 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/506 (20130101) C12N 2770/32122 (20130101) C12N 2770/32123 (20130101) C12N 2770/32134 (20130101) C12N 2770/32151 (20130101) Enzymes C12Y 304/22028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6854 (20130101) G01N 33/56972 (20130101) G01N 33/56983 (20130101) G01N 2333/09 (20130101) G01N 2333/9513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10866622 | Deloatch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland) |
| ASSIGNEE(S) | Government of the United States as represented by Director National Security Agency (, None) |
| INVENTOR(S) | Daryle D. Deloatch (Severn, Maryland) |
| ABSTRACT | A secure charging device provides a charge signal from a host device to an end-user device to charge a battery of the end-user device. The secure charging device includes data transmission logic for transmitting data signals from the host device to the end-user device. The secure charging device also include data monitoring logic for monitoring the data transferred from the host device to the end-user device. Alternatively, the data monitoring logic may include logic for terminating the data transmission signal. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/216325 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/266 (20130101) Original (OR) Class G06F 21/606 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) H02J 7/0047 (20130101) H02J 2207/30 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10868984 | Charlton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States as represented by the Director, National Security Agency (Fort George G. Meade, Maryland) |
| ASSIGNEE(S) | Government of the United States as represented by Director, National Security Agency (, None) |
| INVENTOR(S) | Sarah T. Charlton (Frederick, Maryland); Jeffrey B. Farr (Severn, Maryland) |
| ABSTRACT | An improved method of determining a camera fingerprint and matching fingerprints is provided. A pixel-wise mass is defined and pixel positions having a low pixel-wise mass are identified. Once identified, the fingerprint values associated with those pixel positions are exchanged with statistically distributed random fingerprint values. Because the replacement values are statistically distributed, an improved fingerprint is provide resulting in improved accuracy of fingerprint matching. |
| FILED | Thursday, November 15, 2018 |
| APPL NO | 16/192258 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14605 (20130101) Pictorial Communication, e.g Television H04N 5/341 (20130101) H04N 5/357 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10866186 | Schoegl |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ingmar Schoegl (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Ingmar Schoegl (Baton Rouge, Louisiana) |
| ABSTRACT | Embodiments of the present application are directed toward a focusing Schlieren technique that is capable of adding color-coded directional information to the visualization of density gradients. Other advantages of the technique can include that it does not require manual calibration, has a simple design and is sensitive enough to be used in compact experimental setups. Certain embodiments include the use of a color-coded source image that replaces the conventional source grid. The technique may benefit from a computer-controlled digital background, which is used for both illumination and display of color-coded source images. |
| FILED | Wednesday, January 03, 2018 |
| APPL NO | 15/860978 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/661 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/274 (20130101) G01N 21/455 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 17/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10865644 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KEYSTONE SYNERGISTIC ENTERPRISES, INC. (Port Saint Lucie, Florida) |
| ASSIGNEE(S) | KEYSTONE SYNERGISTIC ENTERPRISES, INC. (Port Saint Lucie, Florida) |
| INVENTOR(S) | Bryant Walker (Palm City, Florida); Raymond Walker (Port Saint Lucie, Florida) |
| ABSTRACT | A rotor for use in an aircraft engine, that has been repaired by (a) welding together a first portion of a damaged blade of the rotor and a second portion of metal to form a weld nugget, (b) compressively stressing the weld nugget throughout its volume, and (c) heat treating the compressively stressed weld nugget to recrystallize metal therein. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467173 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0006 (20130101) B23K 15/0093 (20130101) B23K 26/0006 (20130101) B23K 26/20 (20130101) B23K 26/21 (20151001) B23K 2101/001 (20180801) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/005 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/005 (20130101) Original (OR) Class F01D 5/147 (20130101) Jet-propulsion Plants F02K 9/52 (20130101) F02K 9/58 (20130101) F02K 9/62 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/41 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49318 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10867855 | Higashi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Robert E. Higashi (Shorewood, Minnesota); Son T. Lu (Plymouth, Minnesota); Elenita Chanhvongsak (Lakeville, Minnesota) |
| ABSTRACT | One or more embodiments are directed to establishing electrical connections through silicon wafers with low resistance and high density, while at the same time maintaining processability for further fabrication. Such connections through silicon wafers enable low resistance connections from the top side of a silicon wafer to the bottom side of the silicon wafer. |
| FILED | Monday, May 13, 2019 |
| APPL NO | 16/410694 |
| ART UNIT | 2896 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76831 (20130101) H01L 21/76844 (20130101) H01L 21/76873 (20130101) H01L 21/76898 (20130101) Original (OR) Class H01L 23/481 (20130101) H01L 23/53238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 15, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201215.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page