FedInvent™ Patents
Patent Details for Tuesday, December 22, 2020
This page was updated on Monday, March 27, 2023 at 06:15 AM GMT
Department of Health and Human Services (HHS)
| US 10869611 | Ernst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE QUEEN'S MEDICAL CENTER (Honolulu, Hawaii); THE UNIVERSITY OF HAWAII (Honolulu, Hawaii); THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin); UWM RESEARCH FOUNDATION, INC. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Queen's Medical Center (Honolulu, Hawaii); The University of Hawaii (Honolulu, Hawaii); The Medical Collene of Wisconsin, Inc. (Milwaukee, Wisconsin); UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Thomas Edmund Prieto (Grafton, Wisconsin); Brian Stewart Randall Armstrong (Shorewood, Wisconsin) |
| ABSTRACT | This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/837240 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/721 (20130101) A61B 5/1127 (20130101) A61B 5/1128 (20130101) A61B 5/7292 (20130101) A61B 6/0492 (20130101) A61B 6/547 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/28 (20130101) G01R 33/56509 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00624 (20130101) G06K 2009/3291 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/70 (20170101) Pictorial Communication, e.g Television H04N 7/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869629 | Sejdic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of die Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Ervin Sejdic (Pittsburgh, Pennsylvania); Amro El-Jaroudi (Pittsburgh, Pennsylvania); James Coyle (Harmony, Pennsylvania); Joshua Dudik (Bethesda, Maryland); Mingui Sun (Pittsburgh, Pennsylvania); Zhi-Hong Mao (Sewickley, Pennsylvania) |
| ABSTRACT | A method of classifying a swallow of a subject includes obtaining vibration data that is based on and indicative of a number of vibrations resulting from the swallow, and using a computer implemented deep learning classifier to classify the swallow based on the vibration data. Also, a system for classifying a swallow of a subject includes a computing device implementing a deep learning classifier. The computing device includes a processor apparatus structured and configured to receive vibration data that is based on and indicative of a number of vibrations resulting from the swallow, and use the deep learning classifier to classify the swallow based on the vibration data. The deep learning classifier may comprise a single layer or a multi-layer Deep Belief network. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 16/323556 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4205 (20130101) Original (OR) Class A61B 2562/0219 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/088 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 3/0472 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869630 | Searl |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Jeff P. Searl (Overland Park, Kansas) |
| ABSTRACT | A device for measuring the pressure applied between a user's tongue and palate includes a body shaped to fit complimentarily against the user's palate and a pressure sensor affixed to the body such that the device has a total thickness less than 4 millimeters. |
| FILED | Tuesday, January 26, 2016 |
| APPL NO | 15/007022 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/682 (20130101) A61B 5/4552 (20130101) Original (OR) Class A61B 2562/12 (20130101) A61B 2562/0247 (20130101) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 7/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) B29C 39/38 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869637 | Fairchild et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Karen D. Fairchild (Charlottesville, Virginia); Douglas E. Lake (Charlottesville, Virginia); Brynne Sullivan (Charlottesville, Virginia) |
| ABSTRACT | A method and system for generating pulse oximetry predictive scores for predicting adverse outcomes in preterm infants. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/801226 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/48 (20130101) A61B 5/1455 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 2503/045 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2230/205 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869652 | Carpenter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); University of Leeds (Yorkshire, United Kingdom) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); University of Leeds (Leeds, United Kingdom) |
| INVENTOR(S) | Thomas Carpenter (Leeds, United Kingdom); M. Wasequr Rashid (Atlanta, Georgia); F. Levent Degertekin (Atlanta, Georgia); Steven Freear (Leeds, United Kingdom); David Matthew Joseph Cowell (Leeds, United Kingdom) |
| ABSTRACT | The disclosed technology relates to imaging catheters. A method is provided that includes: receiving, from a plurality of transducers disposed on a catheter probe, a corresponding plurality of analog signals; selectively sampling the plurality of analog signals; multiplexing to produce a sequence of samples; and transmitting the sequence of samples to a receiver circuit. The receiver circuit includes a clock; an analog to digital converter (ADC) in communication with the clock; and a sampling phase correction circuit in communication with the clock and the ADC. The method further includes: determining optimum sampling times based on measured signal delays associated with the system; adjusting a phase of the clock based on the measured signal delays; and communicating the phase-adjusted clock to the transmitter circuit for the selective sampling of the analog signals. Certain embodiments of the disclosed technology may further be utilized in conjunction with beamforming. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/768435 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0402 (20130101) A61B 8/12 (20130101) A61B 8/56 (20130101) Original (OR) Class A61B 8/58 (20130101) A61B 8/4488 (20130101) A61B 8/5207 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/5208 (20130101) G01S 7/52022 (20130101) G01S 7/52025 (20130101) G01S 7/52034 (20130101) G01S 7/52077 (20130101) G01S 7/52079 (20130101) G01S 7/52087 (20130101) G01S 7/52095 (20130101) G01S 15/8915 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869680 | Marionneaux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CLEMSON UNIVERSITY (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Alan Michael Marionneaux (Greenville, South Carolina); Michael David Stokes (Simpsonville, South Carolina); George Marion Seignious, IV (Mt. Pleasant, South Carolina); Alison Santillo (Ponte Vedra Beach, Florida); Jeremy Mercuri (Piedmont, South Carolina); Nicholas Freeman (Ponte Vedra Beach, Florida); Adam Marrocco (Central, South Carolina); Steven Brian Singleton (Vail, Colorado); Brian Curtis Keim (Landrum, South Carolina) |
| ABSTRACT | A medical positioning bracket is described that provides users with the ability to attach and secure multiple bone tunnel drill guides into a single working unit. Users can manipulate each drill guide independently and lock the drill guides at desired locations relative to one another to achieve precise bone tunnel angles and locations. |
| FILED | Thursday, February 18, 2016 |
| APPL NO | 15/046697 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1714 (20130101) A61B 17/1757 (20130101) A61B 17/1764 (20130101) Original (OR) Class A61B 17/1778 (20161101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869773 | Martinez-Luna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | College Park Industries, Inc. (Warren, Michigan) |
| ASSIGNEE(S) | College Park Industries, Inc. (Warren, Michigan) |
| INVENTOR(S) | Carlos Humberto Martinez-Luna (Boylston, Massachusetts); Michael Alfred Delph, II (Port Jefferson Station, New York); Taylor Raven Duckworth (Merrimack, New Hampshire); Todd Richard Farrell (Waltham, Massachusetts); Thane Robert Hunt (Colchester, Connecticut); Craig Malone Kelly (Dracut, Massachusetts); Kevin Edward Keough (Sharon, Massachusetts); Carlton Winslow King (Westfield, Massachusetts); Benjamin Douglas Pulver (Naples, New York); Todd William Roberts (Saint Inigoes, Maryland); Benjamin Edward McDonald (Holliston, Massachusetts) |
| ABSTRACT | A prosthetic finger includes a main body and a terminal gripper at an end of the main body for enabling fine-motor grasping skills. The terminal gripper has at least two tongs movable relative to one another. The prosthetic finger includes a gripping mode and a flexion mode. In the gripping mode, the tongs of the terminal gripper are able to move relative to one another while the main body is not able to flex, and in the flexion mode, the main body is able to flex while the at two tongs is not able to move relative to one another. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/156722 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/72 (20130101) A61F 2/586 (20130101) Original (OR) Class A61F 2/588 (20130101) A61F 2/5044 (20130101) A61F 2002/6854 (20130101) A61F 2002/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869847 | Pearlman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Eric Pearlman (Irvine, California); Mark Kester (Afton, Virginia) |
| ABSTRACT | A method for treating and preventing diseases associated with neutrophil infiltration, particularly ocular diseases, is provided, which method comprises administering to a subject in need thereof an effective amount of ceramide or a derivative thereof. Also provided is a composition for treating diseases associated with neutrophil infiltration, the composition comprising ceramide or a derivative thereof. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/046246 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/164 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869850 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Bruce A. Freeman (Pittsburgh, Pennsylvania); Francisco J. Schopfer (Pittsburgh, Pennsylvania) |
| ABSTRACT | Nitro oleic acid and related metabolites are agonists of PPAR-γ. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-γ, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-γ. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/748453 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/201 (20130101) Original (OR) Class A61K 31/201 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869856 | Debnath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York Blood Center, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | New York Blood Center, Inc. (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Asim Kumar Debnath (Fort Lee, New Jersey); Francesca Curreli (West New York, New Jersey); Peter D. Kwong (Bethesda, Maryland); Young Do Kwon (Bethesda, Maryland) |
| ABSTRACT | Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/777559 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Acyclic or Carbocyclic Compounds C07C 25/00 (20130101) C07C 233/01 (20130101) Heterocyclic Compounds C07D 207/30 (20130101) C07D 207/34 (20130101) C07D 277/20 (20130101) C07D 403/12 (20130101) C07D 405/14 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869860 | Cravatt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vividion Therapeutics, Inc. (San Diego, California); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | VIVIDION THERAPEUTICS, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Benjamin F. Cravatt (La Jolla, California); Matthew Patricelli (San Diego, California); Dean Stamos (San Diego, California); Gabe Simon (San Diego, California); Benjamin Horning (San Diego, California); David Weinstein (San Diego, California); Ekaterina Vinogradova (San Diego, California) |
| ABSTRACT | Disclosed herein are compositions and methods for modulating cereblon neosubstrates. A small molecule modulator of Formula (I*), or a pharmaceutically acceptable salt or solvate thereof can be used to modulate cereblon neosubstrates. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/503415 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) A61K 31/439 (20130101) A61K 31/445 (20130101) Original (OR) Class A61K 31/501 (20130101) A61K 31/4545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869865 | Desai |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Serv (Bethesda, Maryland) |
| INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland) |
| ABSTRACT | The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2 (I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/292722 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/50 (20130101) A61K 31/422 (20130101) A61K 31/423 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/498 (20130101) A61K 31/501 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4355 (20130101) A61K 31/4439 (20130101) A61K 31/4741 (20130101) A61K 39/015 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/84 (20130101) C07D 241/44 (20130101) C07D 263/57 (20130101) C07D 277/54 (20130101) C07D 281/16 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 491/048 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) Peptides C07K 14/445 (20130101) C07K 16/205 (20130101) C07K 2319/21 (20130101) C07K 2319/43 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869866 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Beibei Chen (Sewickley, Pennsylvania); Rama K. Mallampalli (Sewickley, Pennsylvania) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/444879 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/341 (20130101) A61K 31/381 (20130101) A61K 31/402 (20130101) A61K 31/427 (20130101) A61K 31/435 (20130101) A61K 31/444 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4418 (20130101) A61K 31/5375 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 11/06 (20180101) A61P 19/00 (20180101) A61P 25/00 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 211/01 (20130101) C07C 211/53 (20130101) C07C 229/38 (20130101) Heterocyclic Compounds C07D 207/06 (20130101) C07D 211/14 (20130101) C07D 213/06 (20130101) C07D 213/36 (20130101) C07D 213/38 (20130101) C07D 231/12 (20130101) C07D 233/61 (20130101) C07D 233/64 (20130101) C07D 239/26 (20130101) C07D 265/30 (20130101) C07D 277/28 (20130101) C07D 295/135 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869868 | Armstrong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Scott A. Armstrong (New York, New York) |
| ABSTRACT | Disclosed are methods for inhibiting proliferation of or inducing apoptosis in certain leukemia cells or both. The methods comprise contacting a leukemia cell exhibiting an NPM1 mutation with a pharmacologic inhibitor of interaction between MLL and menin. More broadly, disclosed are methods for treating a susceptible leukemia using pharmacologic inhibition of Menin-MLL interaction. Also disclosed are methods for treating such leukemias using inhibition of Menin-MLL interaction in combination with DOT1L inhibition. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 16/072876 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/7064 (20130101) A61K 31/7064 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869871 | Markowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Dallas, Texas) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); James K.V. Wilson (Dallas, Texas); Bruce Posner (Richardson, Texas); Joseph Ready (Carrollton, Texas); Monika Antczak (Ft. Worth, Texas); Yongyou Zhang (Cleveland, Ohio); Amar Desai (Cleveland, Ohio); Stanton Gerson (Hunting Valley, Ohio); William Greenlee (Cleveland, Ohio); Sung Yeun Yang (Busan, South Korea); KiBeom Bae (Busan, South Korea) |
| ABSTRACT | Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 15/785259 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/519 (20130101) A61K 31/4365 (20130101) A61K 31/5377 (20130101) Original (OR) Class Heterocyclic Compounds C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869873 | Einav et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Shirit Einav (Palo Alto, California); Rina Barouch-Bentov (Palo Alto, California); Gregory Neveu (Palo Alto, California); Amotz Zivav (Palo Alto, California) |
| ABSTRACT | The invention provides a method for treating viral infections and coinfections through the use of inhibitory agents that prevent a unique viral structural protein motifs from binding to host proteins from the clathrin adaptor proteins family and subsequently preventing viral replication. |
| FILED | Monday, May 09, 2016 |
| APPL NO | 15/150293 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/517 (20130101) A61K 31/553 (20130101) Original (OR) Class Beer; Preparation of Beer by Fermentation; Preparation of Malt for Making Beer; Preparation of Hops for Making Beer C12C 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/10 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869880 | Karin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael Karin (La Jolla, California); Zhenyu Zhong (San Diego, California) |
| ABSTRACT | Provided herein are methods of treating NLRP3 inflammasome-associated diseases and disorders. Also, disclosed are methods for screening for agents useful in such methods. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/451674 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/127 (20130101) A61K 31/713 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869887 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Kenan Christopher Garcia (Menlo Park, California); Jonathan Sockolosky (San Francisco, California); Lora Picton (Foster City, California) |
| ABSTRACT | Engineered orthogonal cytokine receptor/ligand pairs, and methods of use thereof, are provided. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916689 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 2039/5156 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/1034 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869889 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Michael C. Jensen (Bainbridge Island, Washington); Stanley R. Riddell (Sammamish, Washington); Michael Hudecek (Leipzig, Germany) |
| ABSTRACT | The present invention provides nucleic acids, vectors, host cells, methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring CD8+ central memory T cells or combinations of central memory T cells with CD4+ T cells that are genetically modified to express a chimeric receptor. In embodiments the genetically modified host cell comprises a nucleic acid comprising a polynucleotide coding for a ligand binding domain, a polynucleotide comprising a customized spacer region, a polynucleotide comprising a transmembrane domain, and a polynucleotide comprising an intracellular signaling domain. It has been surprisingly found that the length of the spacer region can affects the ability of chimeric receptor modified T cells to recognize target cells in vitro and affects in vivo efficacy of the chimeric receptor modified T cells. Pharmaceutical formulations produced by the method, and methods of using the same, are also described. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657666 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/7151 (20130101) C07K 14/70521 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/2803 (20130101) C07K 2317/64 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869908 | Devreotes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Peter Devreotes (Towson, Maryland); Huaqing Cai (Baltimore, Maryland); Marc Edwards (Baltimore, Maryland); Jun Liu (Clarksville, Maryland); Michele Vitolo (Baltimore, Maryland); Thomas Lampert (Baltimore, Maryland); Yu Long (Ellicott City, Maryland); Alexandra Debonnes (Meyrieu-les-Étangs, France) |
| ABSTRACT | Methods of inducing cell death by hyperactivation of motility networks are provided. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 16/080975 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 7/00 (20130101) A61H 23/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/22 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/366 (20130101) A61K 31/404 (20130101) A61K 31/505 (20130101) A61K 31/655 (20130101) A61K 31/5415 (20130101) A61K 38/12 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2501/48 (20130101) C12N 2501/999 (20130101) C12N 2527/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869920 | Pletnev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Rockville, Maryland); The Government of the United States, as Represented by The Secretary of The Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary, Department of Health and Human Services (Rockville, Maryland); The Government of the United States, as represented by The Secretary of The Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Alexander G. Pletnev (Gaithersburg, Maryland); Joseph R. Putnak (Silver Spring, Maryland); Robert M. Chanock (Bethesda, Maryland); Brian R. Murphy (Bethesda, Maryland); Stephen S. Whitehead (Bethesda, Maryland); Joseph E. Blaney (Gettysburg, Pennsylvania) |
| ABSTRACT | The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596175 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24143 (20130101) C12N 2770/24162 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6888 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869921 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Shan Lu (Hopkinton, Massachusetts); Shixia Wang (Northborough, Massachusetts) |
| ABSTRACT | Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV are disclosed. The compositions and methods described herein are for the use of a nucleic acid composition that encodes one or more different HIV envelope glycoproteins. The synthetic, codon-optimized DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV polypeptide compositions for inducing an immune response against HIV are also disclosed. Methods for using the polypeptide compositions before, at the same time as, and/or after administration of the DNA compositions are provided. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/180519 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16134 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869926 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Shibin Zhou (Owings Mills, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); KiBem Kim (Lutherville, Maryland) |
| ABSTRACT | Impressive responses have been observed in patients treated with checkpoint inhibitory anti-PD-1 or anti-CTLA-4 antibodies. However, immunotherapy against poorly immunogenic cancers remains a challenge. Treatment with both anti-PD-1 and anti-CTLA-4 antibodies were unable to eradicate large, modestly immunogenic CT26 tumors or metastatic 4T1 tumors. However, co-treatment with epigenetic modulating drugs and checkpoint inhibitors markedly improved treatment outcomes, curing more than 80% of them. Functional studies revealed that the primary targets of the epigenetic modulators were myeloid-derived suppressor cells (MDSCs). A PI3K-inhibitor that reduced circulating MDSCs also cured 80% of mice with metastatic 4T1 tumors when combined with immune checkpoint inhibitors. Thus, cancers resistant to immune checkpoint blockade can be cured by eliminating MDSCs. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 15/326186 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 31/4406 (20130101) A61K 31/4406 (20130101) A61K 35/742 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2818 (20130101) C07K 2317/34 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869936 | Bogyo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Matthew S. Bogyo (Redwood City, California); Martijn Verdoes (Nijmegen, Netherlands) |
| ABSTRACT | Activity-based probe compounds for use in labeling a cysteine protease are provided. The compounds are targeted to the protease through a specific targeting element. The compounds additionally include a detectable element, such as a fluorescent label, a radiolabel, or a chelator. In some cases, the compounds additionally include a quenching element that is released upon reaction with the protease. Also provided are compositions comprising the compounds and methods for using the compounds, for example in labeling a protease in an animal and in visualizing a tumor in an animal. |
| FILED | Saturday, December 23, 2017 |
| APPL NO | 16/338682 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870112 | Sharei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Armon R. Sharei (Watertown, Massachusetts); Viktor A. Adalsteinsson (Kennett Square, Pennsylvania); Nahyun Cho (Closter, New Jersey); Robert S. Langer (Newton, Massachusetts); J. Christopher Love (Somerville, Massachusetts); Klavs F. Jensen (Lexington, Massachusetts) |
| ABSTRACT | Isolating or identifying a cell based on a physical property of said cell can include providing a cell suspension; passing said suspension through a microfluidic channel that includes a constriction; passing the cell suspension through the constriction; and, contacting said cell suspension solution with a compound. The constriction can be sized to preferentially deform a relatively larger cell compared to a relatively smaller cell. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/145865 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/08 (20130101) B01L 2400/0487 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 5/0693 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 33/574 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870202 | Gregg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Robert D. Gregg (Richardson, Texas); Edgar A. Bolivar (Richardson, Texas); David P. Allen (Richardson, Texas); Walter E. Voit (Dallas, Texas) |
| ABSTRACT | A dielectric elastomer system (DES) variable stiffness actuator (VSA) is provided. In an embodiment, the DES VSA includes a variable stiffness module (VSM). The VSM includes a DES that softens when energized and stiffens when unpowered, an outer frame, and an inner frame member. The stiffness of the DES is variable. The outer frame supports the DES and the inner frame member, which is disposed within the DES. The inner frame member is configured to be displaceable with respect to the outer frame. The DES VSA also includes an actuation motor mechanically coupled to the inner frame member that is configured to cause a force to be applied to the inner frame member and the actuation motor is configured to control an equilibrium position of the DES VSA. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/111072 |
| ART UNIT | 2846 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0009 (20130101) B25J 9/123 (20130101) B25J 9/1633 (20130101) Original (OR) Class B25J 9/1694 (20130101) B25J 19/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870616 | Scanlan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Thomas Scanlan (Portland, Oregon); Jordan Devereaux (Portland, Oregon); Andrew Placzek (Portland, Oregon); Tapasree Banerji (Portland, Oregon); Skylar Ferrara (Portland, Oregon); James Matthew Meinig (Portland, Oregon); Tania Banerji (Portland, Oregon) |
| ABSTRACT | Disclosed are halo substituted derivative compounds of sobetirome with improved pharmacological characteristics relative to sobetirome, pharmaceutical compositions that include those compounds and methods of treating diseases such as neurodegenerative disorders using those pharmaceutical compositions. |
| FILED | Monday, December 09, 2019 |
| APPL NO | 16/707604 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 39/07 (20130101) C07C 43/315 (20130101) Original (OR) Class C07C 59/115 (20130101) C07C 65/34 (20130101) C07C 235/20 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870618 | Chou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| INVENTOR(S) | Chung-Jen James Chou (Mt. Pleasant, South Carolina); Jesse McClure (Charleston, South Carolina); Cheng Zhang (Charleston, South Carolina); Elizabeth Inks (Charleston, South Carolina) |
| ABSTRACT | Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 16/340458 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 243/00 (20130101) C07C 243/26 (20130101) C07C 243/32 (20130101) C07C 243/38 (20130101) Original (OR) Class C07C 2603/02 (20170501) C07C 2603/04 (20170501) Heterocyclic Compounds C07D 209/14 (20130101) C07D 213/87 (20130101) C07D 307/68 (20130101) C07D 307/85 (20130101) C07D 333/38 (20130101) C07D 333/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870636 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Pasi Janne (Needham, Massachusetts); Hwan Geun Choi (Daegu, South Korea); Jaebong Jang (Boston, Massachusetts) |
| ABSTRACT | The application relates to a compound having Formula (I): which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/290153 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 403/04 (20130101) Original (OR) Class C07D 403/14 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870640 | El-Deiry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wafik S. El-Deiry (Philadelphia, Pennsylvania); Xiaobing Tian (Philadelphia, Pennsylvania) |
| ABSTRACT | Prodigiosin analogs which reactivate the p53 pathway are provided, as well as compositions of these compounds, and methods for reactivation of the p53 pathway using these compounds are provided. The prodigiosin analogs may be used to treat cancer in which p53 mutation plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among others. |
| FILED | Saturday, April 27, 2019 |
| APPL NO | 16/396669 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870651 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Yanke Liang (Brookline, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7)), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject. |
| FILED | Wednesday, December 23, 2015 |
| APPL NO | 15/538763 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/4162 (20130101) A61K 31/4162 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 487/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870670 | Christofidou-Solomidou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Melpo Christofidou-Solomidou (Eagleville, Pennsylvania); Kyriacos C. Nicolaou (La Jolla, California); Roman A. Valiulin (Atlanta, Georgia); Nicholas Simmons (Houston, Texas); Philipp M. Heretsch (Houston, Texas) |
| ABSTRACT | The invention relates to processes for preparing (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside and compositions comprising the same. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042866 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 41/18 (20130101) C07C 67/31 (20130101) C07C 67/303 (20130101) C07C 67/343 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/18 (20130101) Original (OR) Class C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870682 | Messer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | William Messer (Portland, Oregon); Ralph Baric (Haw River, North Carolina); Aravinda de Silva (Chapel Hill, North Carolina); Boyd Yount (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/105346 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/1825 (20130101) C07K 16/1081 (20130101) C07K 2317/76 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870687 | Hinrichs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland) |
| INVENTOR(S) | Christian S. Hinrichs (Bethesda, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E7, E711-19. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention are also provided. Also disclosed are methods of detecting the presence of a condition in a mammal and methods of treating or preventing a condition in a mammal, wherein the condition is cancer, HPV 16 infection, or HPV-positive premalignancy. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/205631 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1774 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2319/00 (20130101) C07K 2319/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/57484 (20130101) G01N 2333/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870689 | Hla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Timothy T. Hla (Wellesley, Massachusetts); Steven L. Swendeman (Cambridge, Massachusetts); Annarita DiLorenzo (Ithaca, New York); Teresa Sanchez (Ithaca, New York) |
| ABSTRACT | The present disclosure is directed to an engineered phospholipid or lysophospholipid (e.g., sphingosine 1-phosphate (S1P)) chaperone derived from an Apolipoprotein M (ApoM)-Fc fusion protein having an extended half life in vivo. The disclosed ApoM-Fc fusion protein provides a safe, efficient and effective means of delivering S1P to endothelial cells and to all tissues of the body. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 16/326089 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/553 (20130101) A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 47/544 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/02 (20180101) A61P 9/10 (20180101) A61P 9/12 (20180101) Peptides C07K 14/00 (20130101) C07K 14/775 (20130101) Original (OR) Class C07K 19/00 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870705 | Marasco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts) |
| ABSTRACT | The present invention provides chimeric antigen receptor cells specific for carbonic anhydrase IX (CAIX) and methods of using same for treatment of CAIX expressing cancers such as renal cell carcinoma. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 15/537780 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/2013 (20130101) A61K 39/0011 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 2317/51 (20130101) C07K 2317/60 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) C12N 5/0638 (20130101) C12N 9/88 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 402/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870709 | Wisniewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Thomas M. Wisniewski (Staten Island, New York); Fernando Goni (New York, New York) |
| ABSTRACT | The present invention relates to antibodies and binding fragments thereof that bind the β-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding to the non-toxic, non-pathological forms of these proteins or peptides These antibodies and binding fragments thereof are suitable for the diagnosis, prevention, and treatment of protein conformational disorders including all amyloid diseases. |
| FILED | Saturday, July 22, 2017 |
| APPL NO | 16/319682 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 7/06 (20130101) C07K 14/00 (20130101) C07K 16/18 (20130101) C07K 16/44 (20130101) Original (OR) Class C07K 2317/30 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870823 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | LEHIGH UNIVERSITY (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Yaling Liu (Ambler, Pennsylvania); Antony Thomas (Bethlehem, Pennsylvania) |
| ABSTRACT | Described herein are apparatus comprising: a first layer comprising a first microfluidic channel; a second layer comprising a second microfluidic channel; and a membrane for culturing cells; along with methods of making and using same. |
| FILED | Friday, June 12, 2015 |
| APPL NO | 14/737809 |
| ART UNIT | 1799 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 25/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870850 | Ge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SomaGenics, Inc. (Santa Cruz, California) |
| ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
| INVENTOR(S) | Qing Ge (Beijing, China PRC); Brian H. Johnston (Scotts Valley, California); Mark A. Behlke (Coralville, Iowa); Heini Ilves (Santa Cruz, California); Anne Dallas (Santa Cruz, California) |
| ABSTRACT | Aspects of the present invention include the production and use of chemically modified RNAi agents (e.g., shRNAs) in gene silencing applications. The chemically modified RNAi agents disclosed herein have reduced immunostimulatory activity, increased serum stability, or both, as compared to a corresponding RNAi agent not having the chemical modification. Compositions containing chemically modified RNAi agents according to aspects of the present invention (including pharmaceutical compositions) and kits containing the same are also provided. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 15/725870 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 31/7125 (20130101) A61K 47/554 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/318 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/531 (20130101) C12N 2310/3515 (20130101) C12N 2310/3521 (20130101) C12N 2320/30 (20130101) C12N 2320/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870851 | Stampfer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Martha R. Stampfer (Oakland, California); James C. Garbe (San Francisco, California); Lukas Vrba (Tucson, Arizona); Bernard W. Futscher (Tucson, Arizona) |
| ABSTRACT | Aspects of the present disclosure include RNAs that confer a mortal phenotype and nucleic acids encoding same. Liposomes, recombinant cells, and pharmaceutical compositions that include the RNAs or nucleic acids encoding same are also provided. Further provided are methods involving quantifying MORT RNAs and/or determining the methylation status of the MORT promoter, as well as methods that employ the RNAs or nucleic acids encoding same. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/764255 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 15/79 (20130101) C12N 15/88 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2310/113 (20130101) C12N 2510/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870852 | Dey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Bijan K. Dey (Slingerlands, New York); Paul Andrew Yates (Charlottesville, Virginia) |
| ABSTRACT | The application discloses compositions and methods for preventing and treating diabetic retinopathy. It is disclosed herein that an inhibitor of microRNA-let-7b administered to the eye of a subject in need thereof is useful for preventing and treating several problems associated with diabetic retinopathy and plays a role in vasculature stabilization, increasing retinal thickness, reducing retinal capillary dropout, diminishing microvascular leakage, preventing or treating hyperproliferation of microvascular cells, and stabilizing aberrant neovascularization. The invention includes the use of various kinds of inhibitors of microRNA-let-7b, including, but not limited to, an antagomir of miRNA-let-7b. A useful compound of the invention can be administered into the eye, including intravitreally. A useful antagomir is Dy547-mA(*)mA(*)mCmCmAmCmAmCmAmAmCmCmUmAmCmUmAmCmCmU(*) mC(*)mA (*)(3′-Chl). |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/765736 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/7088 (20130101) A61K 31/7125 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/3231 (20130101) C12N 2310/3515 (20130101) C12N 2310/3517 (20130101) C12N 2310/3525 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870853 | Schaefer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); THE ROCKEFELLER UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); THE ROCKEFELLER UNIVERSITY (New York, New York) |
| INVENTOR(S) | Anne Schaefer (New York, New York); Paul Greengard (New York, New York) |
| ABSTRACT | The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148015 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 67/0276 (20130101) A01K 2217/052 (20130101) A01K 2217/075 (20130101) A01K 2217/203 (20130101) A01K 2227/105 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/185 (20130101) A61K 49/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3515 (20130101) C12N 2310/3521 (20130101) C12N 2310/3521 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870854 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Hao Zhu (Dallas, Texas); Shuyuan Zhang (Dallas, Texas) |
| ABSTRACT | Embodiments of the present disclosure include compositions and methods related to certain siRNA compositions for the treatment of cancer. In specific embodiments, siRNAs are employed for treatment of cancer, including at least liver cancer. Therapeutic methods, compositions, and kits are encompassed in the disclosure. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 16/308669 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/127 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1077 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) C12N 2330/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870872 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Henry Hung-yi Lee (Brookline, Massachusetts); George M. Church (Brookline, Massachusetts); Reza Kalhor (East Boston, Massachusetts) |
| ABSTRACT | The disclosure provides methods for making a polynucleotide wherein the addition of nucleotides can be physically, chemically and/or enzymatically controlled. The methods include combining a selected nucleotide, cations, an error prone or template independent DNA polymerase at a reaction site including an initiator sequence attached thereto and having a 3′ terminal nucleotide, wherein the reaction reagents can be modulated and under conditions that allow covalent addition of one or more of a selected nucleotide to the 3′ terminal nucleotide such that the selected nucleotide becomes a 3′ terminal nucleotide, and repeating the addition step until the polynucleotide is formed. |
| FILED | Thursday, March 30, 2017 |
| APPL NO | 16/090640 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2565/519 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870874 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amunix Pharmaceuticals, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Amunix Pharmaceuticals, Inc. (South San Francisco, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. C. Stemmer (Los Gatos, California); Nathan C. Geething (Santa Clara, California) |
| ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955046 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870881 | Soper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); NORTHEASTERN UNIVERSITY (Boston, Massachusetts); BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Steven A. Soper (Baton Rouge, Louisiana); Francis Barany (New York, New York); George Grills (Trumansburg, New York); Robin McCarley (Prairieville, Louisiana); Collin J. McKinney (Durham, North Carolina); Dorel Moldovan (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); Dimitris Nikitopoulos (Baton Rouge, Louisiana); Sunggook Park (Baton Rouge, Louisiana); Elizabeth J. Podlaha-Murphy (West Roxbury, Massachusetts) |
| ABSTRACT | The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure within each bioreactor; a cleaving enzyme immobilized to the support structure and operatively positioned within the bioreactor chamber to cleave monomer or multimer units of a biopolymer molecule operatively engaged by the cleaving enzyme; and one or more time-of-flight channels formed in the solid substrate and fluidically coupled to said one or more bioreactor chambers. Each of the time-of-flight channels have two or more sensors including at least (i) a first sensor contacting the time-of-flight channel proximate to the input end of the channel and (ii) a second sensor contacting the time-of-flight channel proximate to the output end of channel. The present invention further relates to methods of sequencing and identifying biopolymer molecules using the device. |
| FILED | Monday, February 19, 2018 |
| APPL NO | 15/898943 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/027 (20130101) B01L 2200/0663 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44791 (20130101) G01N 33/6803 (20130101) G01N 33/48721 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870883 | Gundlach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Michael Niederweis (Homewood, Alabama); Thomas Z. Butler (Seattle, Washington); Mikhail Pavlenok (Birmingham, Alabama); Mark A. Troll (Seattle, Washington); Suja Sukumaran (Dublin, California) |
| ABSTRACT | Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/996084 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/04 (20130101) Peptides C07K 14/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2523/31 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/00 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 33/6872 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870885 | Regev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Alexander K. Shalek (Cambridge, Massachusetts); Rahul Satija (New York, New York); Hongkun Park (Lexington, Massachusetts) |
| ABSTRACT | This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences dendritic cell (DC) response(s), for example, dendritic cell maturation, dendritic cell antiviral response(s) and/or dendritic cell inflammatory response(s), as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences dendritic cell response(s) in a variety of therapeutic and/or diagnostic indications. |
| FILED | Friday, September 04, 2015 |
| APPL NO | 14/846219 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101) G01N 33/6893 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870886 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts Medical Center (Shrewsbury, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Peter L. Jones (Boston, Massachusetts); Takako Jones (Boston, Massachusetts); Johnny Salameh (Boston, Massachusetts); Colin Quinn (Boston, Massachusetts); Oliver D. King (Boston, Massachusetts) |
| ABSTRACT | The present invention includes methods of determining whether an individual in need thereof has, or is at risk of developing, facioscapulohumeral muscular dystrophy (FSHD). |
| FILED | Wednesday, October 07, 2015 |
| APPL NO | 15/516291 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870888 | Salomon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Daniel Salomon (San Diego, California); Sunil M. Kurian (San Diego, California); Steven Head (Lakeside, California); Michael M. Abecassis (Highland Park, Illinois); John J. Friedewald (Chicago, Illinois); Josh Levitsky (Evanston, Illinois) |
| ABSTRACT | Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 15/898513 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/245 (20130101) Electric Digital Data Processing G06F 19/3481 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/26 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870890 | Vogelstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Luis Diaz (Ellicott City, Maryland); Nickolas Papadopoulos (Towson, Maryland); George J. Netto (Baltimore, Maryland); Ralph Hruban (Baltimore, Maryland); Isaac A. Kinde (Beaumont, California) |
| ABSTRACT | TERT promoter mutations occur in both papillary and flat lesion bladder cancers, are the most frequent genetic alterations identified to date in noninvasive precursor lesions of the bladder, are detectable in urine, and appear to be strongly associated with bladder cancer recurrence. The TERT promoter mutations are useful urinary biomarker for both the early detection and monitoring of bladder neoplasia. |
| FILED | Tuesday, March 22, 2016 |
| APPL NO | 15/077284 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871484 | Kosa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BIOO Scientific Corporation (Austin, Texas) |
| ASSIGNEE(S) | BIOO Scientific Corporation (Austin, Texas) |
| INVENTOR(S) | Nicolas M. Kosa (Austin, Texas); Joseph F. Krebs (Austin, Texas); Darshan N. Kasal (Fort Worth, Texas) |
| ABSTRACT | Polyaromatic hydrocarbons (PAH) from industrial waste and oil spills are a recurrent threat to food safety due to their stability and toxicity. Existing methods to establish the concentrations of PAH in environmental and food samples rely on expensive and laborious methodology. The teachings herein provide methods and kits for detecting the presence or absence of PAH. In certain embodiments, the quantity of PAH in a sample can be determined. |
| FILED | Monday, August 24, 2015 |
| APPL NO | 14/833886 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) Original (OR) Class G01N 2333/90241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871534 | Setsompop et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Kawin Setsompop (Charlestown, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts); Zijing Dong (Beijing, China PRC); Hua Guo (Beijing, China PRC); Fuyixue Wang (Cambridge, Massachusetts); Timothy G. Reese (Bedford, Massachusetts) |
| ABSTRACT | Systems and methods for accelerated magnetic resonance imaging using a tilted reconstruction kernel to synthesize unsampled k-space data in phase encoded and point spread function (“PSF”) encoded k-space data are provided. Images reconstructed from the data have reduced B0-related distortions and reduced T2* blurring. In general, data are acquired with systematically optimized undersampling of the PSF and phase encoding subspace. Parallel imaging reconstruction is implemented with a B0 inhomogeneity informed approach to achieve greater than twenty-fold acceleration of the PSF encoding dimension. A tilted reconstruction kernel is used to exploit the correlations in the phase encoding-PSF encoding subspace. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429467 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/565 (20130101) G01R 33/4818 (20130101) Original (OR) Class G01R 33/5619 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871539 | Basser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter J. Basser (Washington, District of Columbia); Dan H. Benjamini (Rockville, Maryland) |
| ABSTRACT | Described herein are exemplary methods for estimating a nonparametric joint radius-length (R-L) distribution of an ensemble of porous elements represented generally by finite cylinders. Some described methods comprise estimating an eccentricity distribution of a group of anisotropic porous elements. For example, disclosed methods can be applied to estimate a nonparametric joint R-L distribution of injured axons in nervous tissue, muscle tissue, plant elements, or other porous materials. Employing a novel three dimensional (3-D) double pulsed-field gradient (d-PFG) magnetic resonance (MR) acquisition scheme, both the marginal radius and length distributions of a population of generally cylindrical porous elements can be obtained. The marginal radius and length distributions can then b e used to constrain and stabilize the estimate of the joint radius-length distribution. Using the marginal distributions as constraints allows the joint R-L distribution to be reconstructed from an underdetermined system (i.e., more variables than equations). |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 15/529412 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/567 (20130101) Original (OR) Class G01R 33/56341 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871745 | Ozcan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Alon Greenbaum (Durham, California); Yibo Zhang (Los Angeles, California); Alborz Feizi (Los Angeles, California); Wei Luo (Los Angeles, California) |
| ABSTRACT | A method for lens-free imaging of a sample or objects within the sample uses multi-height iterative phase retrieval and rotational field transformations to perform wide FOV imaging of pathology samples with clinically comparable image quality to a benchtop lens-based microscope. The solution of the transport-of-intensity (TIE) equation is used as an initial guess in the phase recovery process to speed the image recovery process. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for any focus adjustment, and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. In an alternative embodiment, a synthetic aperture approach is used with multi-angle iterative phase retrieval to perform wide FOV imaging of pathology samples and increase the effective numerical aperture of the image. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 15/500880 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1475 (20130101) G01N 2015/144 (20130101) G01N 2015/1006 (20130101) G01N 2015/1445 (20130101) G01N 2015/1454 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 1/0891 (20130101) G03H 2001/005 (20130101) G03H 2001/046 (20130101) G03H 2001/0447 (20130101) G03H 2001/0454 (20130101) G03H 2001/0816 (20130101) G03H 2001/0883 (20130101) G03H 2001/2655 (20130101) G03H 2210/42 (20130101) G03H 2226/02 (20130101) G03H 2227/03 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872619 | Goldhor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Speech Technology and Applied Research Corporation (Lexington, Massachusetts); Richard S. Goldhor (Belmont, Massachusetts) |
| ASSIGNEE(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Richard S. Goldhor (Belmont, Massachusetts); Keith Gilbert (Framingham, Massachusetts); Joel MacAuslan (Nashua, New Hampshire) |
| ABSTRACT | A system processes data signals consisting of sums of independent signal terms, zero or more of which signal terms may already have been identified, in order to generate one or more additional terms. Deflated versions of the data signals are created by subtracting from the data signals any previously identified signal terms. Additional independent signal terms are computed using a set of reference signals organized into mutually independent partioning support sets. The images of each support set are computed on the data signals. Computed images on a data signal that are non-zero are identified as additional independent signal terms of that data signal. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 16/746603 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/0272 (20130101) G10L 25/51 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872679 | Cai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Long Cai (Pasadena, California); Ahmet F. Coskun (Pasadena, California) |
| ABSTRACT | Disclosed herein are methods and systems for analyzing visual data from multiple rounds of hybridization interactions where the same molecular target is detected by probes with different detectable labels. In particular, disclosed herein are methods and systems for analyzing sequential hybridization images for molecular profiling, where the images are obtained using multiplex fluorescence in situ hybridization (FISH). |
| FILED | Friday, July 17, 2015 |
| APPL NO | 14/802919 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 35/00 (20190201) G16B 45/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873172 | Fu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Walter Fu (Ithaca, New York); Frank Wise (Ithaca, New York) |
| ABSTRACT | The technology described in this document can be used to implement an optical device including a seed pump laser to produce pump seed laser pulses at a pump wavelength, a pulse stretcher operable to stretch a pulse duration of the pump seed laser pulses to produce stretched pump seed laser pulses, a pump fiber amplifier including one or more fiber gain media to receive the seed pump laser pulses to produce a pump laser beam of pump laser pulses, a signal laser to produce a signal laser beam at a signal wavelength different from the pump wavelength, an optical module coupled to combine the pump laser beam and the signal laser beam, and a fiber optical parametric amplifier (OPA) to cause a nonlinear parametric interaction in the nonlinear fiber medium to produce an output signal beam, an output idler laser beam at an idler wavelength, and an output pump beam. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/372226 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/067 (20130101) H01S 3/1062 (20130101) H01S 3/1083 (20130101) Original (OR) Class H01S 3/06754 (20130101) H01S 3/08086 (20130101) H01S 3/094003 (20130101) H01S 3/094076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10869851 | Ieronimakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The United States Government as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Nicholas M. Ieronimakis (Tacoma, Washington); Andrew S. Thagard (Portsmouth, Virginia); Sarah M. Estrada (Lacey, Washington); Peter Napolitano (Steilacoom, Washington) |
| ABSTRACT | Compositions and methods of inhibiting Nur77 in a subject for treatment of perinatal neuroinflammation, preterm labor, or preterm birth are provided. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916353 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/216 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869920 | Pletnev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Rockville, Maryland); The Government of the United States, as Represented by The Secretary of The Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary, Department of Health and Human Services (Rockville, Maryland); The Government of the United States, as represented by The Secretary of The Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Alexander G. Pletnev (Gaithersburg, Maryland); Joseph R. Putnak (Silver Spring, Maryland); Robert M. Chanock (Bethesda, Maryland); Brian R. Murphy (Bethesda, Maryland); Stephen S. Whitehead (Bethesda, Maryland); Joseph E. Blaney (Gettysburg, Pennsylvania) |
| ABSTRACT | The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596175 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101) C12N 2770/24143 (20130101) C12N 2770/24162 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6888 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10869958 | Burbank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| ASSIGNEE(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| INVENTOR(S) | Jeffrey H. Burbank (Boxford, Massachusetts); Dennis M. Treu (Castle Rock, Colorado); Daniel J. Rubery, Jr. (Windham, New Hampshire); Scott W. Newell (Ipswich, Massachusetts); James M. Brugger (Newburyport, Massachusetts); William J. Schnell (Libertyville, Illinois); William K. Weigel (Portland, Maine); Steven A. White (Hudson, Massachusetts); Mark T. Wyeth (Andover, Massachusetts); Jerome James (Vestavia, Alabama); David Desouza (Essex, Massachusetts); Joseph E. Turk, Jr. (North Andover, Massachusetts); Garrett Casey (Methuen, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381363 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/14 (20130101) A61M 1/34 (20130101) A61M 1/165 (20140204) A61M 1/341 (20140204) A61M 1/1605 (20140204) Original (OR) Class A61M 1/1613 (20140204) A61M 1/1615 (20140204) A61M 1/1647 (20140204) A61M 1/3403 (20140204) A61M 1/3434 (20140204) A61M 1/3437 (20140204) A61M 1/3441 (20130101) A61M 1/3444 (20140204) A61M 1/3448 (20140204) A61M 1/3607 (20140204) A61M 1/3609 (20140204) A61M 1/3635 (20140204) A61M 2205/15 (20130101) A61M 2205/058 (20130101) A61M 2205/502 (20130101) A61M 2205/702 (20130101) A61M 2205/3331 (20130101) A61M 2205/3334 (20130101) A61M 2205/3341 (20130101) A61M 2205/3351 (20130101) A61M 2205/3355 (20130101) A61M 2205/3365 (20130101) A61M 2205/3368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870111 | Ramsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); William Hampton Henley (Chapel Hill, North Carolina) |
| ABSTRACT | A fluidic device includes a plurality of reaction wells, typically in a dense array, with at least one bead retention segment in fluid communication with and spatially separated from at least one signal detection segment. A respective bead retention segment can be configured to hold a single bead, which can have a reagent attached thereto. |
| FILED | Tuesday, July 19, 2016 |
| APPL NO | 15/742616 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00317 (20130101) B01J 2219/00648 (20130101) B01J 2219/00702 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0668 (20130101) B01L 2300/0877 (20130101) B01L 2300/0893 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/00029 (20130101) G01N 2035/00158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870140 | Pingilley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John D. Pingilley (Bettendorf, Iowa); Amanda L. Badger (Eldridge, Iowa); Dale A. Phipps (Taylor Ridge, Illinois) |
| ABSTRACT | A guide system for use in electro-processing a bore of a gun barrel includes a non-conductive external bore guide and a non-conductive internal bore guide. The external bore guide is an adapter that is configured to removably engage the outside of the gun barrel and includes a conduit formed therein. The conduit is disposed such that it is axially aligned with a bore of the gun barrel when the external bore guide is engaged with the gun barrel. The internal bore guide is elongated and includes an axial recess that is sized to seat an electro-processing electrode (an anode). A method for uniformly plating the bore includes moving an anode through the gun barrel at one or more rate(s) of travel to uniformly plate the bore is also disclosed. The plating is sufficiently uniform to conform to military specifications. The systems, methods, support structures, etc. described herein are particularly well-suited to plating small-bore gun barrels. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 16/385790 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/152 (20130101) Original (OR) Class Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/02 (20130101) F41A 21/18 (20130101) F41A 21/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870694 | Marasco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts) |
| ABSTRACT | The present invention comprises methods of using a humanized monoclonal antibody that binds to the human immunoglobulin heavy chain variable region germline gene VH1-69 to treat B-cell disorders. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 16/330188 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39566 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/2803 (20130101) C07K 16/4241 (20130101) C07K 2317/24 (20130101) C07K 2317/35 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870757 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| INVENTOR(S) | Benjamin W. C. Garcia (Tremonton, Utah); Robert S. Larson (Harrisville, Utah) |
| ABSTRACT | An insulation material includes a matrix comprising a reaction product formed from a silicon carbide precursor resin and a silicon dioxide precursor resin. At least one filler, such as hollow glass microspheres and/or carbon fiber is dispersed within the matrix. A rocket motor includes a case, the insulation material within and bonded to the case, and a solid propellant within the case. An insulation precursor includes a silicon carbide precursor resin, a silicon dioxide precursor resin, and the at least one filler. Related methods are also disclosed. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045352 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/042 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/06 (20130101) C08K 7/28 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 83/02 (20130101) Original (OR) Class Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 183/04 (20130101) Jet-propulsion Plants F02K 9/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870845 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Global Life Sciences Solutions Operations UK Ltd (Sheffield, United Kingdom) |
| ASSIGNEE(S) | Global Life Sciences Solutions Operations UK Ltd (Sheffield, United Kingdom) |
| INVENTOR(S) | John Richard Nelson (Clifton Park, New York); Bing Li (Clifton Park, New York) |
| ABSTRACT | A method is provided herein, wherein the method of capturing a target nucleic acid, comprises applying a nucleic acid capture probe to a capture zone of a needs definition, wherein the nucleic acid capture probe having a first molecular weight comprises at least a sequence that is complimentary to at least a portion of the target nucleic acid sequence and the nucleic acid capture probe is substantially immobilized at the capture zone of the substrate. The method further comprises applying a sample comprising the target nucleic acid having a second molecular weight to a sample application zone of the substrate; wherein the sample comprising the target nucleic acid flows across a length of the substrate from the sample application zone to the capture zone by lateral flow, and the target nucleic acid is captured by the nucleic acid capture probes by hybridization to the capture zone. |
| FILED | Thursday, December 11, 2014 |
| APPL NO | 14/566865 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870853 | Schaefer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); THE ROCKEFELLER UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); THE ROCKEFELLER UNIVERSITY (New York, New York) |
| INVENTOR(S) | Anne Schaefer (New York, New York); Paul Greengard (New York, New York) |
| ABSTRACT | The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148015 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 67/0276 (20130101) A01K 2217/052 (20130101) A01K 2217/075 (20130101) A01K 2217/203 (20130101) A01K 2227/105 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/185 (20130101) A61K 49/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3515 (20130101) C12N 2310/3521 (20130101) C12N 2310/3521 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870918 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haitao Liu (Solon, Ohio); Feng Zhou (New York, New York) |
| ABSTRACT | A method of forming a carbonized composition includes providing an organic composition, forming a protective layer over the organic composition, increasing temperature to carbonize the organic composition and for a period of time to form the carbonized composition, and removing the protective layer from the carbonized composition. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571911 |
| ART UNIT | 1796 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 18/1283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871355 | Flater, IV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Govt as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip J. Flater, IV (Niceville, Florida); Charles M. Jenkins (Ft Walton Beach, Florida) |
| ABSTRACT | A munition includes a triply periodic minimal surface (TPMS) structure attached to an inner surface of a cylindrical tube. The TPMS structure is formed by an additive manufacturing process to promote fluid permeability and to reduce pressure drop to prevent trapped air and maximize surface area contact at a structure and liquid interface. An explosive material is introduced into one or more upper apertures of the TPMS in a flowable state to fill the TPMS structure n a compartmentalized arrangement that provides stiffness to the munition. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/819237 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/208 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871361 | Skowron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Concurrent Technologies Corporation (Johnstown, Pennsylvania) |
| ASSIGNEE(S) | Concurrent Technologies Corporation (Johnstown, Pennsylvania) |
| INVENTOR(S) | Todd Skowron (Johnstown, Pennsylvania); Juan Valencia (Johnstown, Pennsylvania); Shawn Rhodes (Somerset, Pennsylvania) |
| ABSTRACT | Disclosed is a cartridge case for various caliber ammunition that can consist essentially of a powdered metal and/or powdered metal alloy(s) that is formed into the cartridge case through an injection mold processing. Also disclosed is a method for forming a cartridge case, which may include use of Metal Injection Molding (“MIM”) processes to produce the cartridge case which retains a primer, propellant, and/or a bullet. Also disclosed are embodiments related to a case telescoped cartridge that may include a cap and a body. The body can consist essentially of or consists entirely of a powdered metal and/or powdered metal alloy(s) that has been formed through MIM. The cap can comprise plastic that has been formed through plastic molding or comprise powdered metal and/or powdered metal alloy(s) that has been formed through MIM. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/729983 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0062 (20130101) B22F 3/16 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/28 (20130101) F42B 5/045 (20130101) F42B 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871419 | Sydney |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anish J. Sydney (Arlington, Virginia) |
| ABSTRACT | A fluid-dynamic test device is implementable in a fluid tunnel such as a wind tunnel or water tunnel. The exemplary inventive device features an outer case and four foils connected to and projecting inward from the case, wherein each foil is rotatable about its spanwise axis and is thus positionable at a selected angle of attack with respect to current generated in the tunnel. The respective axes or span-lines of the four foils lie in a vertical geometric plane in a crisscross configuration, each axis/span-line directed inward toward the point in the vertical plane that is centric relative to the case. Two axes/span-lines are aligned in a horizontal direction, and two axes/span-lines are aligned in a vertical direction. Generated current passes through the inventive device at perpendiculars to the vertical plane, thereby forming a wake that is predominately characterized by mutually interactive tip vortices corresponding to the four foils. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/885461 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/065 (20130101) Original (OR) Class G01M 10/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871445 | Cochenour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Patuxent River, Maryland) |
| INVENTOR(S) | Brandon Cochenour (Alexandria, Virginia); Amanda Alley (Great Mills, Maryland); Alan Edward Laux (Great Mills, Maryland); Linda Mullen (Chesapeake Beach, Maryland) |
| ABSTRACT | A method and system for optical vortex transmissometry. The method uses optical orbital angular momentum (OAM) and optical vortices to discriminate coherent non-scattered light from incoherent scattered light. The system includes a laser which transmits a Gaussian laser beam through a medium. An OAM generating device is placed before a photodetector receiver. Coherent, non-scattered light passing through the OAM generating device forms an optical vortex, used to discriminate against the unwanted scattered signal that doesn't form a vortex. Alternatively, the system includes a transmitter which generates one or more OAM modes which are transmitted through a turbid medium. At the receiver, an OAM detection device analyzes the OAM mode spectrum of the received light. Coherent non-scattered light retains the OAM encoded at the transmitter, while scattered light does not. The attenuation of the channel is determined by comparison of the received OAM mode spectrum relative to the transmitted OAM mode spectrum. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267438 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/538 (20130101) Original (OR) Class G01N 21/5907 (20130101) G01N 2021/5988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871477 | Graupmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mary M. Graupmann (Corona, California); Christopher H. Clark (Riverside, California); Michael L. Bishop (Norco, California) |
| ABSTRACT | Contaminant cleaning systems and related methods are provided. Exemplary embodiments include a reactive substance generator to produce or transfer reactive substance(s) that react with contaminant(s) on an item into a cleaning chamber. An analysis section can be attached to the cleaning chamber to perform gas analysis on gas samples brought into the analysis chamber that measure reaction byproducts from the reactive substance(s) interaction with the contaminants. An exemplary valve system can selectively couple the reactive substance generator, the analysis section, and the cleaning chamber. An exemplary pumping system, in combination with the valve system, can selectively generate differential pressure/vacuum levels between the reactive substance generator vs cleaning chamber as well as between the cleaning chamber and analysis section. For example, the analysis chamber can be configured to have a higher vacuum than the cleaning chamber to facilitate passage of gas test samples into the analysis chamber. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/243769 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 9/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0009 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/32862 (20130101) H01J 37/32981 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871554 | Keyser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian K. Keyser (Shalimar, Florida); Luke A. Ausley (Niceville, Florida); Chad M. Welsh (Niceville, Florida) |
| ABSTRACT | A LADAR having a transmitter and a receiver. The transmitter includes a laser for delivering an original beam pulse having a time duration. A nonlinear element receives the original beam pulse and outputs a multispectral incident beam pulse. For each wavelength component of the incident beam pulse, a unique wavelength-dependent variation of intensity is imparted over the time duration of the incident beam pulse. This creates a unique waveform shape for each component. Output optics direct the incident beam pulse onto a target, which reflects from the target as a scattered beam pulse. The receiver includes a single-pixel sensor for receiving the scattered beam pulse and measuring and outputting an intensity of the scattered beam pulse over time, which creates a scattered beam pulse envelope. A processor receives the scattered beam pulse envelope, applies factors to fit the waveform shapes to the scattered beam pulse envelope, and derives a reflectivity of the target for each of the wavelength components from the factors. |
| FILED | Thursday, March 08, 2018 |
| APPL NO | 15/915573 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4802 (20130101) Original (OR) Class G01S 7/4814 (20130101) G01S 7/4816 (20130101) G01S 7/4818 (20130101) G01S 17/06 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 2202/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871745 | Ozcan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Alon Greenbaum (Durham, California); Yibo Zhang (Los Angeles, California); Alborz Feizi (Los Angeles, California); Wei Luo (Los Angeles, California) |
| ABSTRACT | A method for lens-free imaging of a sample or objects within the sample uses multi-height iterative phase retrieval and rotational field transformations to perform wide FOV imaging of pathology samples with clinically comparable image quality to a benchtop lens-based microscope. The solution of the transport-of-intensity (TIE) equation is used as an initial guess in the phase recovery process to speed the image recovery process. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for any focus adjustment, and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. In an alternative embodiment, a synthetic aperture approach is used with multi-angle iterative phase retrieval to perform wide FOV imaging of pathology samples and increase the effective numerical aperture of the image. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 15/500880 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1475 (20130101) G01N 2015/144 (20130101) G01N 2015/1006 (20130101) G01N 2015/1445 (20130101) G01N 2015/1454 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 1/0891 (20130101) G03H 2001/005 (20130101) G03H 2001/046 (20130101) G03H 2001/0447 (20130101) G03H 2001/0454 (20130101) G03H 2001/0816 (20130101) G03H 2001/0883 (20130101) G03H 2001/2655 (20130101) G03H 2210/42 (20130101) G03H 2226/02 (20130101) G03H 2227/03 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872072 | Medard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts); University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts); University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Kishori Mohan Konwar (Revere, Massachusetts); Prakash Narayana Moorthy (Framingham, Massachusetts); Nancy Ann Lynch (Brookline, Massachusetts); Erez Kantor (Brookline, Massachusetts); Alexander Allister Schwarzmann (Storrs, Connecticut) |
| ABSTRACT | Described are devices, systems and techniques for implementing atomic memory objects in a multi-writer, multi-reader setting. In an embodiment, the devices, systems and techniques use maximum distance separable (MDS) codes, and may be specifically designed to optimize a total storage cost for a given fault-tolerance requirement. Also described is an embodiment to handle the case where some of the servers can return erroneous coded elements during a read operation. |
| FILED | Tuesday, December 12, 2017 |
| APPL NO | 15/838966 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/067 (20130101) G06F 16/00 (20190101) G06F 16/27 (20190101) G06F 16/2329 (20190101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101) H04L 69/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872149 | Alexander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Perspecta Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Scott Alexander (Basking Ridge, New York); Josephine Micallef (Basking Ridge, New Jersey); Joshua Morman (Basking Ridge, New Jersey); Euthimios Panagos (Basking Ridge, New Jersey); Marc Pucci (Basking Ridge, New Jersey); Simon Tsang (Basking Ridge, New Jersey) |
| ABSTRACT | A computer program product, a computer-implemented method, and a computer system include a processor(s) that obtains side channel emanations from a device. The processor(s) analyzes the side channel emanations to identify distinct emanation patterns and timing characteristics, wherein the timing characteristics are associated with transitions between the distinct emanation patterns. The processor(s) generates a non-deterministic finite automaton (NFA) by correlating the distinct emanation patterns with states of the device, where the NFA captures states and state transitions of the device. The processor(s) identifies an anomaly in the device, based on deviation in emanations from the device. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045368 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/556 (20130101) Original (OR) Class G06F 21/562 (20130101) G06F 21/566 (20130101) G06F 21/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872177 | Gupta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Nikhil Gupta (Ossining, New York) |
| ABSTRACT | A method for securing a computer-aided design (CAD)-based shape to prevent shape counterfeiting by unauthorized three-dimensional (3D) printing includes creating and embedding a security element in the CAD-based shape itself. In some embodiments, the method includes splitting (slicing) a first solid of a three-dimensional 3D model into at least two parts, such that the 3D model comprises at least two distinct solids. The shape of the distinct solid(s) may be specified by a plurality of curved surfaces, which are defined by performing a finite element analysis on the CAD-based shape to determine an optimal shape for each curved surface. The method further includes converting the 3D model to a digital surface geometry schema according to a first resolution. The digital surface geometry schema describes the surface geometry of the at least two distinct solids. The first resolution is part of the security controls of the CAD-based shape. The first resolution may be selected based on a shape of the split of the first solid, a location of the split of the first solid, a 3D printer type, an anticipated horizontal print direction, an anticipated vertical print direction, an anticipated slicer software scheme, an anticipated slice thickness, and/or an anticipated slice location. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/710723 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) B33Y 80/00 (20141201) Electric Digital Data Processing G06F 30/00 (20200101) Original (OR) Class G06F 2119/18 (20200101) Pictorial Communication, e.g Television H04N 1/00838 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/02 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872187 | Platzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | André Platzer (Pittsburgh, Pennsylvania); Stefan Mitsch (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method for ensuring that verification results about models apply to cyber-physical systems (CPS) implementations is presented. The invention provides correctness guarantees for CPS executions at runtime. Offline verification of CPS models are combined with runtime validation of system executions for compliance with the model. The invention ensures that the verification results obtained for the model apply to the actual system runs by monitoring the behavior of the world for compliance with the model, assuming the system dynamics deviation is bounded. If, at some point, the observed behavior no longer complies with the model, such that offline verification results no longer apply, provably safe fallback actions are initiated. The invention includes a systematic technique to synthesize provably correct monitors automatically from CPS proofs in differential dynamic logic. |
| FILED | Friday, October 10, 2014 |
| APPL NO | 15/026690 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 30/3323 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872205 | Beller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Paul J. Chase (Fairfax, Virginia); Richard Darden (Leesburg, Virginia); Michael Drzewucki (Woodbridge, Virginia); Edward G. Katz (Washington, District of Columbia); Christopher Phipps (Arlington, Virginia) |
| ABSTRACT | An apparatus comprising a memory and a processor configured for semi-autonomous natural language processing domain adaptation related activities. The processor coupled to the memory and configured to identify a corpus of documents of an evaluation domain and generate a first lexicon based on the corpus of documents of the evaluation domain, and determine a threshold that indicates a sufficiency of domain adaptation of the evaluation domain based at least in part on the first lexicon. The processor is further configured to identify a corpus of documents of a client domain, generate a second lexicon based on the corpus of documents of the client domain, determine a metric associated with the corpus of documents of the client domain and the second lexicon, and determine that domain adaptation of the client domain is complete when the metric exceeds the threshold. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376338 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) G06F 16/3329 (20190101) G06F 16/3344 (20190101) G06F 40/30 (20200101) G06F 40/242 (20200101) G06F 40/284 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872539 | Brueckner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Stephen K. Brueckner (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York) |
| ABSTRACT | An example method includes outputting a graphical dashboard that includes one or more learning objective nodes and one or more skill nodes, selecting one or more software agents that are associated with the one or more skill nodes, providing, to at least one host computing system, an indication of the one or more software agents that are configured to collect parameter data from the at least one host computing system while a trainee performs actions, receiving the parameter data collected by the one or more software agents during execution, determining, based on the parameter data, that the one or more skills represented by the one or more skill nodes have been demonstrated by the trainee, and updating the one or more skill nodes to graphically indicate that one or more represented skills have been demonstrated. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/137735 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 19/0053 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873045 | Dutta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Achyut Kumar Dutta (Sunnyvale, California) |
| ASSIGNEE(S) | Banpil Photonics, Inc. (Santa Clara, California) |
| INVENTOR(S) | Achyut Kumar Dutta (Sunnyvale, California) |
| ABSTRACT | This invention relates to a novel structure of photovoltaic devices (e.g. photovoltaic cells also called as solar cells) are provided. The cells are based on the micro or nano scaled structures which could not only increase the surface area but also have the capability of reducing the reflection and increasing the absorption of incident light. More specifically, the structures are based on 3D structure which are made of electric materials covering semiconductors, insulators, dielectric, polymer, and metallic type materials. By using such structures reflection loss of the light from the cell is significantly reduced, increasing the absorption, which results in increasing the conversion efficiency of the solar cell, and reducing the usage of material while increasing the flexibility of the solar cell. The structures can be also used in other optical devices wherein the reflection loss and absorption are required to enhance significantly improve the device performances. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 15/588575 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2031 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/02327 (20130101) H01L 31/02366 (20130101) H01L 31/03529 (20130101) H01L 51/447 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/543 (20130101) Y02E 10/544 (20130101) Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873340 | Dixon |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ray Dixon (Avenue, Maryland) |
| ABSTRACT | According to one aspect of the invention, a method for making relatively high resolution measurements using relatively low resolution devices includes the steps of: deriving a first anticipated measurement value; using the first anticipated measurement value as an initial feed-forward signal; comparing the initial feed forward signal to a received signal from a sensor, thereby generating a compared signal; scaling the compared signal to full scale of an analog-to-digital converter, thereby generating a scaled signal; delivering the scaled signal in binary form for computation; and iteratively performing the comparing step until the compared signal is below a predetermined threshold value. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 16/667409 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/00 (20130101) H03M 1/06 (20130101) H03M 1/12 (20130101) Original (OR) Class H03M 1/68 (20130101) H03M 1/1071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873471 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Utah State University Research Foundation (North Logan, Utah) |
| ASSIGNEE(S) | Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| INVENTOR(S) | Troy R. Johnson (North Logan, Utah); Jonathan R. Haws (Richmond, Utah); Nathan A. Jensen (Preston, Idaho) |
| ABSTRACT | For measuring an area of interest based on a sensor task and/or routing sensor data, a method discovers a network topology for a network comprising a plurality of network nodes connected by links. The method dynamically generates a minimum spanning tree from the network topology. Given sensor data traverses one link of the minimum spanning tree only once. The method routes a sensor task to a sensor with a sensor motion track that includes an area of interest. The method measures the area of interest with the sensor based on the sensor task. The method routes sensor data from the measurement of the area of interest via links of the minimum spanning tree. |
| FILED | Monday, November 25, 2019 |
| APPL NO | 16/694684 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 40/10 (20200101) G16Y 40/60 (20200101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/00 (20130101) Original (OR) Class H04L 45/021 (20130101) H04L 45/48 (20130101) H04L 45/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10870103 | Striegler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Susanne Striegler (Fayetteville, Arkansas) |
| ABSTRACT | Disclosed herein is a class of chiral binuclear metal complexes for stereoselective hydrolysis of saccharides and glycosides, and more particular chiral binuclear transition metal complex catalysts that discriminate epimeric glycosides and α- and β-glycosidic bonds of saccharides in aqueous solutions at near physiological pHs. The chiral binuclear metal complexes include a Schiff-base-type ligand derived from a chiral diamino building block, and a binuclear transition metal core, each which can be varied for selectivity. The metal core is a Lewis-acidic metal ion, such as copper, zinc, lanthanum, iron and nickel. The Schiff-base may be a reduced or non-reduced Schiff-base derived from aliphatic linear, aliphatic cyclic diamino alcohols or aromatic aldehydes. The ligand can be a penta- or heptadentate ligand derived from pyridinecarbaldehydes, benzaldehydes, linear or cyclic diamines or diamino alcohols. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 15/451478 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2239 (20130101) Original (OR) Class B01J 31/2243 (20130101) B01J 2531/16 (20130101) B01J 2531/0208 (20130101) B01J 2531/0238 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 211/36 (20130101) C07C 215/44 (20130101) C07C 2601/14 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/005 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870749 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jiahua Zhu (Fairlawn, Ohio); Nitin Mehra (Akron, Ohio); Liwen Mu (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Jiahua Zhu (Fairlawn, Ohio); Nitin Mehra (Akron, Ohio); Liwen Mu (Akron, Ohio) |
| ABSTRACT | A process is provided for preparing a thermally conductive polymer composite. The method includes the steps of combining a linear, hydrophilic polymer and an organic, hydrophilic additive to form a blend. The additive includes at least two polar functional groups that are capable of forming hydrogen bonds. A thermally conductive polymer is also provided. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/027736 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/215 (20130101) C08J 5/18 (20130101) C08J 2329/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/17 (20130101) C08K 5/053 (20130101) C08K 5/053 (20130101) C08K 5/175 (20130101) Compositions of Macromolecular Compounds C08L 29/04 (20130101) Original (OR) Class C08L 29/04 (20130101) C08L 29/04 (20130101) C08L 29/04 (20130101) C08L 29/04 (20130101) C08L 29/04 (20130101) C08L 71/02 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 97/005 (20130101) C08L 97/005 (20130101) C08L 2203/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870858 | Hittinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Christopher Todd Hittinger (Madison, Wisconsin); William Gerald Alexander (Madison, Wisconsin) |
| ABSTRACT | Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878698 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/80 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870881 | Soper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); NORTHEASTERN UNIVERSITY (Boston, Massachusetts); BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Steven A. Soper (Baton Rouge, Louisiana); Francis Barany (New York, New York); George Grills (Trumansburg, New York); Robin McCarley (Prairieville, Louisiana); Collin J. McKinney (Durham, North Carolina); Dorel Moldovan (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); Dimitris Nikitopoulos (Baton Rouge, Louisiana); Sunggook Park (Baton Rouge, Louisiana); Elizabeth J. Podlaha-Murphy (West Roxbury, Massachusetts) |
| ABSTRACT | The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure within each bioreactor; a cleaving enzyme immobilized to the support structure and operatively positioned within the bioreactor chamber to cleave monomer or multimer units of a biopolymer molecule operatively engaged by the cleaving enzyme; and one or more time-of-flight channels formed in the solid substrate and fluidically coupled to said one or more bioreactor chambers. Each of the time-of-flight channels have two or more sensors including at least (i) a first sensor contacting the time-of-flight channel proximate to the input end of the channel and (ii) a second sensor contacting the time-of-flight channel proximate to the output end of channel. The present invention further relates to methods of sequencing and identifying biopolymer molecules using the device. |
| FILED | Monday, February 19, 2018 |
| APPL NO | 15/898943 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/027 (20130101) B01L 2200/0663 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44791 (20130101) G01N 33/6803 (20130101) G01N 33/48721 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870918 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haitao Liu (Solon, Ohio); Feng Zhou (New York, New York) |
| ABSTRACT | A method of forming a carbonized composition includes providing an organic composition, forming a protective layer over the organic composition, increasing temperature to carbonize the organic composition and for a period of time to form the carbonized composition, and removing the protective layer from the carbonized composition. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571911 |
| ART UNIT | 1796 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 18/1283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871435 | Yang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shengyuan Yang (West Melbourne, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shengyuan Yang (West Melbourne, Florida) |
| ABSTRACT | The present disclosure provides methods, and related kits, for directing cell attachment and spreading on a substrate and inducing isotropic spreading of cells; provides methods, and related kits, for cell sorting; and further provides methods, and related kits, for guided induction of stem cell differentiation. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652928 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 3/00 (20130101) C12M 25/16 (20130101) C12M 47/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871466 | Mackin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles E. Mackin (Cambridge, Massachusetts); Tomás Apostol Palacios (Cambridge, Massachusetts) |
| ABSTRACT | A sensor device including a substrate that is transparent and/or flexible, and a transparent sensor array disposed on the substrate. The transparent sensor array includes transparent sensor circuits and transparent interconnects electrically coupled to the transparent sensor circuits. Each of the transparent sensor circuits includes a transparent transistor. A transparent slide may include a transparent sensor circuit disposed on a transparent substrate. The slide may be prepared for observation of a specimen by placing the specimen in fluidic communication with the transparent sensor circuit. A flexible sensor device may include an array of transparent sensor circuits disposed on a flexible substrate. The flexible sensor device may be placed on the surface of an object to determine parameters at locations adjacent to the surface of the object. A method of fabricating an integrated circuit may include using a multilayer etch mask of electron-beam resist and photoresist. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/773247 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/30 (20130101) G03F 7/095 (20130101) G03F 7/2022 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0274 (20130101) H01L 21/02527 (20130101) H01L 21/02554 (20130101) H01L 21/02568 (20130101) H01L 29/22 (20130101) H01L 29/24 (20130101) H01L 29/1606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871699 | Reddy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Dileep V. Reddy (Eugene, Oregon); Michael G. Raymer (Eugene, Oregon) |
| ABSTRACT | Apparatus include an optical cavity including an optical coupling portion situated to couple an optical signal input field to an intracavity optical signal field and an optical control input field to an intracavity optical control field, wherein the optical cavity includes a nonlinear optical medium that mediates a selective exchange of at least one predetermined temporal mode between the intracavity optical signal field and an intracavity optical register field based on a nonlinear phase-matched interaction between the intracavity optical signal, control, and register fields and selectable field characteristics of the optical control input field. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530737 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3534 (20130101) G02F 1/3536 (20130101) G02F 1/3544 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871745 | Ozcan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Alon Greenbaum (Durham, California); Yibo Zhang (Los Angeles, California); Alborz Feizi (Los Angeles, California); Wei Luo (Los Angeles, California) |
| ABSTRACT | A method for lens-free imaging of a sample or objects within the sample uses multi-height iterative phase retrieval and rotational field transformations to perform wide FOV imaging of pathology samples with clinically comparable image quality to a benchtop lens-based microscope. The solution of the transport-of-intensity (TIE) equation is used as an initial guess in the phase recovery process to speed the image recovery process. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for any focus adjustment, and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. In an alternative embodiment, a synthetic aperture approach is used with multi-angle iterative phase retrieval to perform wide FOV imaging of pathology samples and increase the effective numerical aperture of the image. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 15/500880 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1475 (20130101) G01N 2015/144 (20130101) G01N 2015/1006 (20130101) G01N 2015/1445 (20130101) G01N 2015/1454 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) Original (OR) Class G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 1/0891 (20130101) G03H 2001/005 (20130101) G03H 2001/046 (20130101) G03H 2001/0447 (20130101) G03H 2001/0454 (20130101) G03H 2001/0816 (20130101) G03H 2001/0883 (20130101) G03H 2001/2655 (20130101) G03H 2210/42 (20130101) G03H 2226/02 (20130101) G03H 2227/03 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872209 | Ha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Unsoo Ha (Cambridge, Massachusetts); Junshan Leng (Boston, Massachusetts); Alaa Khaddaj (Kfarmatta, Lebanon); Yunfei Ma (Santa Clara, California); Tzu Ming Hsu (Cambridge, Massachusetts); Zexuan Zhong (Princeton, New Jersey); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | A system may sense the contents of a closed container, by analyzing a wireless signal that reflects from an RFID tag on the outside of the container. The frequency response of the tag's antenna may be affected by the relative permittivity of the contents and by the tag's environment. The frequency response may be measured in a line-of-sight environment and in a multipath environment. Channel estimates may be calculated, based on the measurements. Channel ratios may be calculated by dividing line-of-sight channel estimates by multipath channel estimates. The resulting channel ratios may be fed into a variational autoencoder, which in turn generates synthetic data that contains information about multipath environments but not the contents. The output of the variational autoencoder may be converted into synthetic channel estimates, which may in turn be employed for anomaly detection, or to train a classifier to classify contents of the container. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 16/601584 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) Original (OR) Class G06K 7/10009 (20130101) G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873026 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael Scott Arnold (Middleton, Wisconsin); Katherine Rose Jinkins (Madison, Wisconsin); Gerald Joseph Brady (Madison, Wisconsin); Padma Gopalan (Madison, Wisconsin) |
| ABSTRACT | Methods for forming carbon nanotube arrays are provided. Also provided are the arrays formed by the methods and electronic devices that incorporate the array as active layers. The arrays are formed by flowing a fluid suspension of carbon nanotubes through a confined channel under conditions that create a velocity gradient across the flowing suspension. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/455587 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) C01B 32/172 (20170801) C01B 2202/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) Original (OR) Class H01L 51/0012 (20130101) H01L 51/0048 (20130101) H01L 51/0558 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/746 (20130101) Y10S 977/847 (20130101) Y10S 977/891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873044 | Xue |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation Inc. (Gainesville, Florida) |
| INVENTOR(S) | Jiangeng Xue (Gainesville, Florida) |
| ABSTRACT | Embodiments of the invention pertain to the use of alloyed semiconductor nanocrystals for use in solar cells. The use of alloyed semiconductor nanocrystals offers materials that have a flexible stoichiometry. The alloyed semiconductor may be a ternary semiconductor alloy, such as AxB1-xC or AB1-yCy, or a quaternary semiconductor alloy, such as AxByC1-x-yD, AxB1-xCyD1-y or ABxCyD1-x-y (where A, B, C, and D are different elements). In general, alloys with more than four elements can be used as well, although it can be much harder to control the synthesis and quality of such materials. Embodiments of the invention pertain to solar cells having a layer incorporating two or more organic materials such that percolated paths for one or both molecular species are created. Specific embodiments of the invention pertain to a method for fabricating nanostructured bulk heterojunction that facilitates both efficient exciton diffusion and charge transport. Embodiments of the subject invention pertain to a solar cell having an architecture that allows for efficient harvesting of solar energy. The organic solar cell architecture can incorporate a host/guest (or matrix/dopant) material system that utilizes the long diffusion lengths for triplet excitons without compromising light absorption efficiency. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/122511 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/424 (20130101) H01L 51/426 (20130101) H01L 51/4213 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873070 | Royer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SOUTH 8 TECHNOLOGIES, INC. (San Diego, California) |
| ASSIGNEE(S) | SOUTH 8 TECHNOLOGIES, INC. (San Diego, California) |
| INVENTOR(S) | James Royer (San Diego, California); Cyrus Sam Rustomji (La Jolla, California); Jungwoo Lee (San Diego, California) |
| ABSTRACT | Disclosed are novel methods and techniques for introducing liquefied gas solvents into electrochemical devices. Unlike conventional electrolytes, the disclosed electrolytes are based on “liquefied gas solvents” mixed with various salts, referred to as “liquefied gas electrolytes.” The disclosed liquefied gas electrolytes can have wide electrochemical potential windows, high conductivity, low temperature capability and/or high-pressure solvent properties. Non-limiting examples of a class of liquefied gases that can be used as solvents for electrolytes include hydrofluorocarbons, and in particular include fluoromethane, difluoromethane, tetrafluoroethane, and pentafluoroethane. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804207 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/36 (20130101) Original (OR) Class H01M 6/24 (20130101) H01M 6/164 (20130101) H01M 10/60 (20150401) H01M 2300/0042 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873172 | Fu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Walter Fu (Ithaca, New York); Frank Wise (Ithaca, New York) |
| ABSTRACT | The technology described in this document can be used to implement an optical device including a seed pump laser to produce pump seed laser pulses at a pump wavelength, a pulse stretcher operable to stretch a pulse duration of the pump seed laser pulses to produce stretched pump seed laser pulses, a pump fiber amplifier including one or more fiber gain media to receive the seed pump laser pulses to produce a pump laser beam of pump laser pulses, a signal laser to produce a signal laser beam at a signal wavelength different from the pump wavelength, an optical module coupled to combine the pump laser beam and the signal laser beam, and a fiber optical parametric amplifier (OPA) to cause a nonlinear parametric interaction in the nonlinear fiber medium to produce an output signal beam, an output idler laser beam at an idler wavelength, and an output pump beam. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/372226 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/067 (20130101) H01S 3/1062 (20130101) H01S 3/1083 (20130101) Original (OR) Class H01S 3/06754 (20130101) H01S 3/08086 (20130101) H01S 3/094003 (20130101) H01S 3/094076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873184 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Fei Wang (Knoxville, Tennessee); Leon M. Tolbert (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee); Kevin Tomsovic (Knoxville, Tennessee); Kai Sun (Knoxville, Tennessee); Shuoting Zhang (Knoxville, Tennessee); Jingxin Wang (Knoxville, Tennessee) |
| ABSTRACT | A system includes a controller that is configured to generate a node control signal and a plurality of switch control signals, a plurality of programmable emulators, each of the plurality of programmable emulators being configurable as one of a plurality of node types responsive to the node control signal, and a plurality of switches that are programmable to couple ones of the plurality of programmable emulators to each other responsive to the plurality of switch control signals. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/165547 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/041 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) Original (OR) Class H02J 3/36 (20130101) H02J 3/385 (20130101) H02J 3/386 (20130101) H02J 2203/20 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873276 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Tianwei Ma (Honolulu, Hawaii); Jian Yu (Honolulu, Hawaii); Enze Ma (Durham, North Carolina) |
| ABSTRACT | Apparatuses and methods for harvesting ambient energy involve repeated circuit reconfiguration. An apparatus includes a primary charge storage device, a first secondary charge storage device, a second secondary charge storage device, and switching circuitry. The switching circuitry is configured to cyclically alter connection of the first and second secondary charge storage devices between a series state and a parallel state. First and second moveable electrically conductive elements may include electrically conductive liquid droplets of materials such as water or mercury. At least one of the primary storage device, the first secondary charge storage device, or the second secondary charge storage device includes a capacitance that varies in response to receipt of ambient energy. Concurrently altering relative capacitance and circuit configuration results in exponential growth of harvested energy. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 16/346676 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873363 | Gollakota et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shyamnath Gollakota (Seattle, Washington); Bryce Kellogg (Seattle, Washington); Vamsi Talla (Seattle, Washington); Joshua R. Smith (Seattle, Washington) |
| ABSTRACT | Examples described herein include devices and systems utilizing backscatter communication to directly generate transmissions in accordance with wireless communication protocols that can be decoded existing devices. Examples include devices that generate 802.11b transmissions using backscatter communication. Examples of network stacks are described which may facilitate backscatter devices to coexist with other devices (e.g. in the ISM band), without incurring, or reducing a need for, the power consumption or carrier sense and medium access control operations. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752214 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/713 (20130101) Original (OR) Class H04B 7/0413 (20130101) Wireless Communication Networks H04W 74/0808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873412 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Polytechnic Institute and State University (Blacksburg, Virginia) |
| INVENTOR(S) | Yan Huang (Blacksburg, Virginia); Y. Thomas Hou (Blacksburg, Virginia); Yongce Chen (Blacksburg, Virginia) |
| ABSTRACT | System and method for using a network with base stations to optimally or near-optimally schedule radio resources among the users are disclosed. In certain embodiments the system and method are designed to operate in real-time (such as but not limited to 100 μs) to schedule radio resources in a 5G NR network by solving for an optimal or near-optimal solution to scheduling problem by decomposing it into a number of small and independent sub-problems, selecting a subset of sub-problems and fitting them into a number of parallel processing cores from one or multiple many-core computing devices, and solving for an optimal or near-optimal solution through parallel processing within approximately 100 μs. In other embodiments, the sub-problems are constructed to have a similar mathematical structure. In yet other embodiments, the sub-problems are constructed to each be solved within approximately 10 s of μs. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039486 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) Original (OR) Class H04L 1/0009 (20130101) H04L 1/0015 (20130101) H04L 1/0026 (20130101) H04L 5/003 (20130101) H04L 5/0053 (20130101) H04L 2001/0093 (20130101) Wireless Communication Networks H04W 72/0453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873446 | Kose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Selcuk Kose (Tampa, Florida); Weize Yu (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Selcuk Kose (Tampa, Florida); Weize Yu (Tampa, Florida) |
| ABSTRACT | Methods and systems are provided for single false key-controlled (SFKC) aggressive voltage scaling (AVS) and multiple parallel false key controlled (MPFKC) AVS countermeasure systems. When a plaintext value is input into a cryptographic circuit for modification by a correct key, power supplied to the cryptographic circuit is scaled based on a result of the plaintext value modified by a false key or by a random number of parallel false keys, which occurs during every clock cycle. The scaling may be triggered when the operating frequency of the cryptographic circuit falls below a threshold, which indicates occurrence of a leakage power attack. A key that is detectable within a power trace of the scaled power provided to the cryptographic circuit, with a highest correlation coefficient relative to a known key, is a key other than the correct key. The MPFKC AVS technique also inhibits unriddling of the input power scaling scheme. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/967171 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 1/28 (20130101) G06F 1/305 (20130101) G06F 1/3203 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/003 (20130101) Original (OR) Class H04L 9/3066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10870173 | Mariella, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Raymond P. Mariella, Jr. (Danville, California); Alexander M. Rubenchik (Livermore, California); Mary A. Norton (Livermore, California) |
| ABSTRACT | Systems for processing a material by submerging the material in a fluid and directing laser pulses at the fluid and the material for processing the material. An embodiment removes the surface of concrete, brick, or rock or minerals in a relatively gentle, energy-efficient, and controlled manner that also confines the material that is removed. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994083 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 7/0042 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/16 (20130101) Original (OR) Class B23K 26/36 (20130101) B23K 26/40 (20130101) B23K 26/0622 (20151001) B23K 26/1224 (20151001) B23K 2103/50 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870851 | Stampfer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Martha R. Stampfer (Oakland, California); James C. Garbe (San Francisco, California); Lukas Vrba (Tucson, Arizona); Bernard W. Futscher (Tucson, Arizona) |
| ABSTRACT | Aspects of the present disclosure include RNAs that confer a mortal phenotype and nucleic acids encoding same. Liposomes, recombinant cells, and pharmaceutical compositions that include the RNAs or nucleic acids encoding same are also provided. Further provided are methods involving quantifying MORT RNAs and/or determining the methylation status of the MORT promoter, as well as methods that employ the RNAs or nucleic acids encoding same. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/764255 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 15/79 (20130101) C12N 15/88 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2310/113 (20130101) C12N 2510/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870858 | Hittinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Christopher Todd Hittinger (Madison, Wisconsin); William Gerald Alexander (Madison, Wisconsin) |
| ABSTRACT | Provided herein are constructs for genome editing or genetic engineering its fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 15/878698 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/80 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870917 | Darling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Naperville, Illinois); Seth W. Snyder (Lincolnwood, Illinois) |
| ABSTRACT | A method of fabricating an foam includes providing a foam comprising a base material. The base material is coated with an inorganic material using at least one of an atomic layer deposition (ALD), a molecular layer deposition (MLD), or sequential infiltration synthesis (SIS) process. The SIS process includes at least one cycle of exposing the foam to a first metal precursor for a first predetermined time and a first partial pressure. The first metal precursor infiltrates at least a portion of the base material and binds with the base material. The foam is exposed to a second co-reactant precursor for a second predetermined time and a second partial pressure. The second co-reactant precursor reacts with the first metal precursor, thereby forming the inorganic material on the base material. The inorganic material infiltrating at least the portion of the base material. The inorganic material is functionalized with a material. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/644569 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/32 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) C23C 16/30 (20130101) C23C 16/045 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 16/45555 (20130101) Hydraulic Engineering E02B 15/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871066 | Kemp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Richard A. Kemp (Albuquerque, New Mexico); Timothy J. Boyle (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to modified proppants and methods of using the modified proppants that use metal ligand tracers to characterize subterranean fluid flow. The metal and ligands are best chosen to be a strongly-coordinating, chelating ligand with a functional group for the chosen flow environment. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937650 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/045 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/267 (20130101) E21B 47/11 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871311 | Coulter |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joshua Oliver Coulter (Kansas City, Missouri) |
| ABSTRACT | A case for an electronic device includes a housing for enclosing the electronic device and a removable heating device that may be placed in or on the housing for warming the electronic device without electricity from the electronic device. The removable heating device includes a pouch enclosing a supersaturated solution and a metal disk. The super saturated solution in the pouch undergoes an exothermic reaction when the disk is actuated. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233798 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Collection, Production or Use of Heat Not Otherwise Provided for F24V 30/00 (20180501) Original (OR) Class Electric Digital Data Processing G06F 1/1626 (20130101) G06F 1/1656 (20130101) Transmission H04B 1/3888 (20130101) Telephonic Communication H04M 1/21 (20130101) H04M 1/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871765 | Barr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Christian Barr (Kansas City, Missouri); Wesley Everhart (Overland Park, Kansas) |
| ABSTRACT | A computing device for controlling the operation of an additive manufacturing machine comprises a memory element and a processing element. The memory element is configured to store a three-dimensional model of a part to be manufactured, wherein the three-dimensional model defines a plurality of cross sections of the part. The processing element is in communication with the memory element. The processing element is configured to receive the three-dimensional model, determine a path across a surface of each cross section, wherein the path includes a plurality of parallel lines, calculate a power for a radiation beam to scan each of the lines, such that the power varies from line to line non-linearly according to a length of the line, and calculate a scan speed for the radiation beam for each of the lines, such that the scan speed varies line to line non-linearly according to the power of the radiation beam. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426540 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/02 (20130101) B23K 15/0086 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10871766 | Barr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kanas City, Missouri) |
| INVENTOR(S) | Christian Barr (Kansas City, Missouri); Wesley Everhart (Overland Park, Kansas) |
| ABSTRACT | A computing device for controlling the operation of an additive manufacturing machine comprises a memory element and a processing element. The memory element is configured to store a three-dimensional model of a part to be manufactured, wherein the three-dimensional model defines a plurality of cross sections of the part. The processing element is in communication with the memory element. The processing element is configured to receive the three-dimensional model, determine a plurality of paths, each path including a plurality of parallel lines, determine a radiation beam power for each line, such that the radiation beam power varies non-linearly according to a length of the line, and determine a radiation beam scan speed for each line, such that the radiation beam scan speed is a function of a temperature of a material used to manufacture the part, the length of the line, and the radiation beam power for the line. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426568 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1056 (20130101) B22F 2003/1057 (20130101) B22F 2203/11 (20130101) B22F 2999/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/02 (20130101) B23K 15/06 (20130101) B23K 15/0086 (20130101) B23K 26/034 (20130101) B23K 26/082 (20151001) B23K 26/127 (20130101) B23K 26/342 (20151001) B23K 26/1224 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/416 (20130101) G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/305 (20130101) H01J 37/3026 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/10 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872705 | Tripathy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho) |
| ABSTRACT | A method of direct oxide reduction includes forming a molten salt electrolyte in an electrochemical cell, disposing at least one metal oxide in the electrochemical cell, disposing a counter electrode comprising a material selected from the group consisting of osmium, ruthenium, rhodium, iridium, palladium, platinum, silver, gold, lithium iridate, lithium ruthenate, a lithium rhodate, a lithium tin oxygen compound, a lithium manganese compound, strontium ruthenium ternary compounds, calcium iridate, strontium iridate, calcium platinate, strontium platinate, magnesium ruthenate, magnesium iridate, sodium ruthenate, sodium iridate, potassium iridate, and potassium ruthenate in the electrochemical cell, and applying a current between the counter electrode and the at least one metal oxide to reduce the at least one metal oxide. Related methods of direct oxide reduction and related electrochemical cells are also disclosed. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 15/886041 |
| ART UNIT | 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/34 (20130101) C25C 3/36 (20130101) C25C 7/025 (20130101) Nuclear Reactors G21C 19/48 (20130101) Original (OR) Class G21C 19/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872734 | Vela-Becerra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Javier Vela-Becerra (Ames, Iowa); Bryan A. Rosales (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Javier Vela-Becerra (Ames, Iowa); Bryan A. Rosales (Ames, Iowa) |
| ABSTRACT | A method of synthesizing a mixed-halide perovskite is disclosed herein. The method includes the steps of mixing a first single-halide perovskite and a second single-halide perovskite to form a solid phase mixture and heating the solid phase mixture at a temperature below a first decomposition temperature of the first single-halide perovskite and below a second decomposition temperature of the second single-halide perovskite for a time sufficient to form the mixed-halide perovskite. During the mixing, the first and second single-halide perovskite are both in the solid phase. A mixed-halide perovskite made according to the method is also disclosed herein. The mixed-halide perovskite is free of amorphous and/or semicrystalline phases. The mixed-halide perovskite can be utilized in a photovoltaic cell in a solar panel. |
| FILED | Tuesday, December 26, 2017 |
| APPL NO | 15/854596 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0029 (20130101) H01G 9/2004 (20130101) Original (OR) Class H01G 9/2077 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/005 (20130101) H01L 51/0025 (20130101) H01L 51/0077 (20130101) H01L 51/422 (20130101) H01L 51/441 (20130101) H01L 51/448 (20130101) H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872737 | Brambilla |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FastCAP SYSTEMS Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | FASTCAP SYSTEMS CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Nicolò Michele Brambilla (Brookline, Massachusetts) |
| ABSTRACT | An ultracapacitor that includes an energy storage cell immersed in an electrolyte and disposed within an hermetically sealed housing, the cell electrically coupled to a positive contact and a negative contact, wherein the ultracapacitor has a gel or polymer based electrolyte and is configured to output electrical energy at temperatures between about −40° C. and about 250° C. Methods of fabrication and use are provided. |
| FILED | Monday, November 28, 2016 |
| APPL NO | 15/362810 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) H01G 11/56 (20130101) Original (OR) Class H01G 11/62 (20130101) H01G 11/64 (20130101) H01G 11/68 (20130101) H01G 11/70 (20130101) H01G 11/80 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872991 | Caswell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SUNPOWER CORPORATION (San Jose, California) |
| ASSIGNEE(S) | SUNPOWER CORPORATION (San Jose, California) |
| INVENTOR(S) | Nathaniel Caswell (Sunnyvale, California); David C. Hosken (Redwood City, California); Jason Kalus (Redwood City, California) |
| ABSTRACT | Solar cell devices as well as method and apparatus for producing solar cell devices are disclosed. Aspects of the disclosure provide a solar cell device that includes a string of solar cells. The string of solar cells are conductively connected in series and arranged in a shingled manner with sides of adjacent solar cells being overlapped. A first metal ribbon segment is conductively bonded to a front surface of an end cell, the front surface being configured to face a light incoming direction to receive energy from a light source. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/950727 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/0508 (20130101) Original (OR) Class H01L 31/02008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873074 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yi Cui (Stanford, California); Nian Liu (Stanford, California); Zhenda Lu (Stanford, California); Jie Zhao (Stanford, California) |
| ABSTRACT | A battery electrode material includes: 1) primary particles formed of an electrochemically active material; and 2) a secondary particle defining multiple, discrete internal volumes, wherein the primary particles are disposed within respective ones of the internal volumes. |
| FILED | Friday, October 03, 2014 |
| APPL NO | 14/506345 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/625 (20130101) H01M 4/626 (20130101) H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873090 | Ito et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yasumasa Ito (Nagoya, Japan); Sanjoy Banerjee (New York, New York) |
| ASSIGNEE(S) | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEWYORK (New York, New York) |
| INVENTOR(S) | Yasumasa Ito (Nagoya, Japan); Sanjoy Banerjee (New York, New York) |
| ABSTRACT | A novel electrode current collector design that can improve performance and extend cycle life for rechargeable batteries based on metal electrodeposition is disclosed. The novel electrode current collector has a reduced effective surface area that can help to balance efficiencies between battery electrodes and to ensure non-uniform electrodeposition of metal onto the anode current collector during charge. One result is mitigation of internal short circuits that can cause a battery to fail prematurely. |
| FILED | Thursday, July 05, 2012 |
| APPL NO | 14/129865 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/70 (20130101) H01M 4/72 (20130101) Original (OR) Class H01M 4/661 (20130101) H01M 10/30 (20130101) H01M 2004/021 (20130101) H01M 2300/0014 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873991 | Prasher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravi Shankar Prasher (Danville, California); Hao Wang (Richmond, California); Justin Palmer Freedman (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ravi Shankar Prasher (Danville, California); Hao Wang (Richmond, California); Justin Palmer Freedman (Berkeley, California) |
| ABSTRACT | A multilayer photonic stack comprising a lower plurality of alternating layers comprising at least A and B and an upper plurality of alternating layers comprising at least C and D, layer A comprises at least one of Al, Au, W, Ag, Ni, Ti, Pt, and Cr, layer B comprises at least one of Al2O3, AlN, MgO, SiO2, TiO2, Si3N4, MgF2, Ta2O5, SiC, Si, Ge, and Indium Tin Oxide (ITO), and layers C and D comprise at least one of Al2O3, AlN, MgO, SiO2, TiO2, Si3N4, MgF2, Ta2O5, SiC, Si, Ge, and Indium Tin Oxide (ITO). |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/879885 |
| ART UNIT | 3754 — Fluid Handling and Dispensing |
| CURRENT CPC | Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874033 | Bilski, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aavid Thermal Corp. (Wilmington, Delaware) |
| ASSIGNEE(S) | Aavid Thermal Corp. (Wilmington, Delaware) |
| INVENTOR(S) | Walter John Bilski, Jr. (Mohnton, Pennsylvania); Sidrit Kosta (Philadelphia, Pennsylvania) |
| ABSTRACT | An electronics rack comprising a first cage, a first heat sink positioned at a rear and in thermal communication with the first cage, a second cage positioned above the first cage, and a second heat sink in thermal communication with the second cage. In another aspect, the present invention provides an electronics rack comprising a frame, a cage, a heat sink positioned at a rear of the frame, and a compliant thermal collector operatively positioned between the cage and the heat sink. The compliant thermal collector can comprise a heat pipe having a non-linear shape that facilitates flexing of the heat pipe to change the length of the thermal collector. The thermal collector advantageously includes a plurality of heat pipes and a contact bar coupling the plurality of heat pipes. Preferably, the rack further includes an adjusting mechanism (e.g., threaded rods) for adjusting a position of the contact bar. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/445554 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20681 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10869866 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Beibei Chen (Sewickley, Pennsylvania); Rama K. Mallampalli (Sewickley, Pennsylvania) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/444879 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/341 (20130101) A61K 31/381 (20130101) A61K 31/402 (20130101) A61K 31/427 (20130101) A61K 31/435 (20130101) A61K 31/444 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4418 (20130101) A61K 31/5375 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 11/06 (20180101) A61P 19/00 (20180101) A61P 25/00 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 211/01 (20130101) C07C 211/53 (20130101) C07C 229/38 (20130101) Heterocyclic Compounds C07D 207/06 (20130101) C07D 211/14 (20130101) C07D 213/06 (20130101) C07D 213/36 (20130101) C07D 213/38 (20130101) C07D 231/12 (20130101) C07D 233/61 (20130101) C07D 233/64 (20130101) C07D 239/26 (20130101) C07D 265/30 (20130101) C07D 277/28 (20130101) C07D 295/135 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10870625 | Wright et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut); United States of America as represented by the Department of Veterans Affairs (Syracuse, New York) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Dennis Wright (Storrs, Connecticut); Amy C. Anderson (, None); Eric Scocchera (Mansfield Center, Connecticut); Narendran Gummudipundi Dayanandan (Mansfield Center, Connecticut); Santosh Keshipeddy (Hamden, Connecticut); Stephanie Reeve (Manchester, Connecticut); Michael N. Lombardo (Manchester, Connecticut); Michael Henry Cynamon (Dewitt, New York) |
| ABSTRACT | The disclosure provides compounds of the formula I and the pharmaceutically acceptable salts thereof. The variables, e.g. R1, R2, R3, R4, A, B, J, V, W, M, J and Ar are defined herein. The disclosure also provides pharmaceutical compositions comprising a compound or salt of formula I and a pharmaceutically acceptable carrier, methods of inhibiting dihydrofolate reductase (DHFR) in vitro or in vivo with a compound or salt of formula I, and methods of treating a bacterial infections, fungal infections, and protozoal infections with a compound or salt of formula I. A compound or salt of formula I can be the first and only active ingredient used in a pharmaceutical composition or method of this disclosure or may be combined with one or more additional active ingredients that are not compounds or salts of formula I. |
| FILED | Monday, January 09, 2017 |
| APPL NO | 16/068262 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/06 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) C07D 239/49 (20130101) Original (OR) Class C07D 403/10 (20130101) C07D 405/06 (20130101) C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10872391 | Juarez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Peter D. Juarez (Hampton, Virginia); Elizabeth D. Gregory (Hampton, Virginia); K. Elliott Cramer (Yorktown, Virginia) |
| ABSTRACT | A method of detecting defects in a composite structure includes applying heat to a surface of a composite structure. Thermographic images or frames captured by a moving camera may be utilized to form temporally aligned images that include temperature data (pixels) from a plurality of frames, wherein the (pixels) comprise data captured at a simple (uniform) time delay from the time at which heat was applied. The temporally aligned thermographic data for the surface region may include variations due to differences in thermal transients caused by defects in the composite structure. The variations in the thermographic data may be utilized to detect one or more defects in the composite structure. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/954126 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/54 (20130101) B29C 70/384 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/10 (20130101) G01J 2005/0077 (20130101) G01J 2005/0081 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8851 (20130101) Image Data Processing or Generation, in General G06T 1/0014 (20130101) Original (OR) Class G06T 7/90 (20170101) G06T 2207/10048 (20130101) G06T 2207/30124 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872987 | Ting et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David Z. Ting (Arcadia, California); Alexander Soibel (South Pasadena, California); Arezou Khoshakhlagh (Pasadena, California); Sarath D. Gunapala (Stevenson Ranch, California) |
| ABSTRACT | Barrier infrared detectors having structures configured to enhance the quantum efficiency, and methods of their manufacture are provided. In particular, device structures for constructing high-performance barrier infrared detectors using novel combinations of p-type and n-type absorber regions and contact regions are provided. The infrared detectors generally incorporate a “p+Bpnn+” structure. The detectors generally comprise, in sequence, a highly p-doped contact layer “p+”, an electron unipolar barrier “B”, a p-type absorber section “p”, and n-type absorber section “n”, and a highly n-doped contact layer “n+”. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/530294 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1463 (20130101) H01L 27/14649 (20130101) H01L 31/101 (20130101) H01L 31/102 (20130101) H01L 31/03046 (20130101) H01L 31/035236 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10870874 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amunix Pharmaceuticals, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Amunix Pharmaceuticals, Inc. (South San Francisco, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. C. Stemmer (Los Gatos, California); Nathan C. Geething (Santa Clara, California) |
| ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955046 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10872619 | Goldhor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Speech Technology and Applied Research Corporation (Lexington, Massachusetts); Richard S. Goldhor (Belmont, Massachusetts) |
| ASSIGNEE(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Richard S. Goldhor (Belmont, Massachusetts); Keith Gilbert (Framingham, Massachusetts); Joel MacAuslan (Nashua, New Hampshire) |
| ABSTRACT | A system processes data signals consisting of sums of independent signal terms, zero or more of which signal terms may already have been identified, in order to generate one or more additional terms. Deflated versions of the data signals are created by subtracting from the data signals any previously identified signal terms. Additional independent signal terms are computed using a set of reference signals organized into mutually independent partioning support sets. The images of each support set are computed on the data signals. Computed images on a data signal that are non-zero are identified as additional independent signal terms of that data signal. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 16/746603 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/0272 (20130101) G10L 25/51 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10870873 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qingdao Vland Biotech Group Co., Ltd. (Qingdao, China PRC) |
| ASSIGNEE(S) | Qingdao Viand Biotech Group Co., Ltd. (Qingdao, China PRC) |
| INVENTOR(S) | Tom Tao Huang (Fremont, California) |
| ABSTRACT | The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020429 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/04 (20130101) Peptides C07K 14/475 (20130101) C07K 14/575 (20130101) C07K 16/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/38 (20130101) C12N 9/2408 (20130101) C12N 9/2411 (20130101) C12N 9/2434 (20130101) C12N 9/2437 (20130101) C12N 15/80 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/12 (20130101) C12P 19/44 (20130101) C12P 21/02 (20130101) C12P 21/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10872122 | Elliott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | John Elliott (Silver Spring, Maryland); Talapady N. Bhat (Gaithersburg, Maryland); Ursula R. Kattner (Germantown, Maryland); Carelyn E. Campbell (Germantown, Maryland); Ram D. Sriram (Ellicott City, Maryland); Eswaran Subrahmanian (Washington, District of Columbia); Jacob Collard (Ithaca, New York); Ira Monarch (Pittsburgh, Pennsylvania) |
| ABSTRACT | A knowledge management system includes: a default knowledge system including: a knowledge system and a knowledge database in communication with the knowledge system; and a knowledge store in communication with the default knowledge system and including: a taxonomy amendment, an annotation amendment, a canonicalization amendment, an ecosystem amendment, a term amendment, and a phrase amendment. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883449 |
| ART UNIT | 2156 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) Original (OR) Class G06F 16/212 (20190101) G06F 16/313 (20190101) G06F 16/3344 (20190101) G06F 40/117 (20200101) G06F 40/169 (20200101) G06F 40/211 (20200101) Computer Systems Based on Specific Computational Models G06N 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10871591 | Atherton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Eric Atherton (Middletown, New Jersey); Matthew Aderholdt (Vineland, New Jersey); Joseph Regensburger (Grove City, Ohio); Lucinda Flaherty (Bradenton, Florida); Joseph Cochran (Egg Harbor Township, New Jersey) |
| ABSTRACT | Systems, methods, and apparatuses are provided for evaluating an image quality of an image produced by an x-ray computed tomography (CT) system. The system includes at least one test article configured to support one or more test objects within an inner volume. The test article includes an exterior shell assembly, a base assembly, a support structure. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 15/514247 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/005 (20130101) Original (OR) Class G01V 5/0008 (20130101) G01V 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10873276 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | UNIVERSITY OF HAWAII (Honolulu, Hawaii) |
| INVENTOR(S) | Tianwei Ma (Honolulu, Hawaii); Jian Yu (Honolulu, Hawaii); Enze Ma (Durham, North Carolina) |
| ABSTRACT | Apparatuses and methods for harvesting ambient energy involve repeated circuit reconfiguration. An apparatus includes a primary charge storage device, a first secondary charge storage device, a second secondary charge storage device, and switching circuitry. The switching circuitry is configured to cyclically alter connection of the first and second secondary charge storage devices between a series state and a parallel state. First and second moveable electrically conductive elements may include electrically conductive liquid droplets of materials such as water or mercury. At least one of the primary storage device, the first secondary charge storage device, or the second secondary charge storage device includes a capacitance that varies in response to receipt of ambient energy. Concurrently altering relative capacitance and circuit configuration results in exponential growth of harvested energy. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 16/346676 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10871552 | Fluhler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Herbert U. Fluhler (Huntsville, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Herbert U. Fluhler (Huntsville, Alabama) |
| ABSTRACT | A method for processing detection and range signals using a digital signal processor generates an interstitial filter that overlaps two adjacent baseline filters of filter bank. The interstitial filter is generated from data outputs of the two adjacent baseline filters using computations that are much simpler than those used to generate baseline filters. The inclusion of interstitial filters in the filter bank improves the resolution and signal to noise ratios of the filter bank. |
| FILED | Saturday, August 11, 2018 |
| APPL NO | 16/101439 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/295 (20130101) Original (OR) Class G01S 13/53 (20130101) G01S 13/582 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/0266 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10873361 | Robinson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
| ABSTRACT | A method includes generating, via a processor, multiple initial vectors, each including N elements. A code map is applied to each of the initial vectors, to produce an associated spreading code vector. Each of the spreading code vectors includes M elements, where M≥N. Using the spreading code vectors, spread signals are produced based on a complex baseband signals. The spread signals are stored in a memory operably coupled to the processor. The first and second spread signals are split into respective sets of spread signals, each uniquely associated with one of multiple transmit antennas. The first and second sets of spread signals are transmitted to respective signal receivers for detection of associated complex baseband signals based on the associated spreading code vectors. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/416144 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/66 (20130101) H04B 1/709 (20130101) Original (OR) Class H04B 1/7097 (20130101) H04B 7/0413 (20130101) Multiplex Communication H04J 11/0023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 22, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201222.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page