FedInvent Patent Applications
Patent Application Details for Thursday, July 15, 2021
This page was updated on Thursday, July 15, 2021 at 11:40 PM GMT
Department of Health and Human Services (HHS)
| US 20210212293 | Lhamon et al. |
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| FUNDED BY |
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| APPLICANT(S) | SIGNAL SOLUTIONS, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael E. Lhamon (Lexington, Kentucky); Anuj Agarwal (Lexington, Kentucky) |
| ABSTRACT | A rack system including a plurality of cages, wherein each cage comprises a respective plurality of outside surfaces, a plurality of housing areas, each housing area corresponding to a respective one cage of the plurality of cages, each housing area comprising a respective plurality of inside surfaces of the rack system and arranged to support at least a portion of one of the respective plurality of outside surfaces of its corresponding one cage, and a plurality of coaxial piezoelectric cables, each coaxial piezoelectric cable corresponding to a respective one cage of the plurality of cages and at least indirectly coupled to its corresponding one cage. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/195653 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/03 (20130101) A01K 1/031 (20130101) A01K 1/0035 (20130101) A01K 1/0157 (20130101) A01K 29/005 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212571 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ji-xin Cheng (Newton, Massachusetts); Yingchun Cao (Natick, Massachusetts); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ji-xin Cheng (Newton, Massachusetts); Yingchun Cao (Natick, Massachusetts) |
| ABSTRACT | An apparatus and method for converting localized laser absorption in lipid-rich biological tissue into ultrasonic waves through thermoelastic expansion to image the entire arterial wall with chemical selectivity and depth resolution. The apparatus including a sensitive quasi-collinear dual-mode photoacoustic/ultrasound catheter with elaborately selected sheath material. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/055260 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/0084 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/02007 (20130101) A61B 5/6852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212629 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE MEDICAL COLLEGE OF WISCONSIN, INC. (MILWAUKEE, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shi-Jiang Li (Brookfield, Wisconsin); Guangyu Chen (Brookfield, Wisconsin); Gang Chen (Wauwatosa, Wisconsin) |
| ABSTRACT | Systems and methods are described for computing a quantitative index that characterizes Alzheimer\'s disease (“AD”) risk events based on a temporally ordered sequence of biomarker events. In general, the systems and methods described here implement a modified event-based probabilistic (“EBP”) model to calculate the risk index from biomarker data. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/062799 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0263 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 5/4842 (20130101) A61B 5/7275 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/56341 (20130101) G01R 33/56366 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212949 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jingwei Xie (Omaha, Nebraska); Sunil Kumar Boda (Omaha, Nebraska) |
| ABSTRACT | Nanofiber segments and nanofiber microspheres are provided as well as methods of use thereof and methods of making. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/044949 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/1641 (20130101) A61K 9/1658 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212955 | ZHENG et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
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| INVENTOR(S) | Siyang ZHENG (State College, Pennsylvania); Cheng GONG (Malden, Massachusetts) |
| ABSTRACT | The present invention relates to compositions and methods for delivery of therapeutic agent. In certain aspects, the invention comprises a metal-organic framework nanoparticle encapsulating a protein. In some aspects, the metal-organic framework nanoparticle encapsulating a protein is coated with an extracellular vesicle membrane. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 17/058925 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 9/5176 (20130101) A61K 9/5192 (20130101) A61K 38/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212969 | SU et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bin SU (Cleveland, Ohio); Monica M. MONTANO (Cleveland, Ohio) |
| ABSTRACT | A method of inducing HEXIM1 expression in cells of a subject includes administering to the cells a compound having the formula, and pharmaceutically acceptable salts thereof. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217084 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 31/18 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212987 | TYAVANAGIMATT et al. |
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| FUNDED BY |
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| APPLICANT(S) | SIGA TECHNOLOGIES, INC. (Corvallis, Oregon) |
| ASSIGNEE(S) | SIGA TECHNOLOGIES, INC. (Corvallis, Oregon) |
| INVENTOR(S) | Shanthakumar R. TYAVANAGIMATT (Sammamish, Washington); Kris HOLT (Colorado Springs, Colorado); Ying TAN (Millbrae, California); Melialani A.C.L.S. ANDERSON (Corvallis, Oregon); Dennis E. HRUBY (Albany, Oregon) |
| ABSTRACT | The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture. |
| FILED | Wednesday, February 15, 2017 |
| APPL NO | 16/071119 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 31/403 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212988 | TUCKER et al. |
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| APPLICANT(S) | Actuate Therapeutics Inc. (Fort Worth, Texas) |
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| INVENTOR(S) | Torry A. TUCKER (Tyler, Texas); Steven IDELL (Tyler, Texas) |
| ABSTRACT | Pharmaceutical compositions and methods are described which rely upon glycogen synthase kinase 3 (form β; GSK 3β) inhibitors, most preferably 9-ING-41, to inhibit fibrotic pulmonary remodeling in vivo including proliferation and differentiation of myofibroblasts to fibrotic fibroblasts in several mouse models. Therapeutic targeting of GSK-3β with the clinically useful specific inhibitor, 9-ING-41, mitigates fibrotic pulmonary remodeling in vivo and provides a mode of therapy of human IPF by specific GSK-3β inhibition with 9-ING-41. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/056238 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 31/407 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212989 | Wandinger-Ness et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angela Wandinger-Ness (Albuquerque, New Mexico); Laurie Hudson (Albuquerque, New Mexico); Larry Sklar (Albuquerque, New Mexico); Zurab Surviladze (Albuquerque, New Mexico); Tudor Oprea (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to molecules which function as modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases (e.g. Rac, Cdc42 and Rho GTPases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-B cell lymphoma, where these GTPases are overexpressed or hyperactivated), sporadic and genetic diseases where activation of Rho GTPases plays a pivotal role (Menkes disease, rheumatoid arthritis, atherosclerosis, diabetes (type 1), Huntington\'s disease and Alzheimer\'s disease) which are mediated through these proteins. Compounds according to the present invention may also be used as a therapy for the treatment of Entamoeba spp. or Acanthamoeba spp. infections, especially including Entamoeba histolytica. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095399 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) A61K 31/407 (20130101) Original (OR) Class A61K 31/415 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 231/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210212997 | Varner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judith Varner (La Jolla, California); Michael C. Schmid (West Kirby, United Kingdom) |
| ABSTRACT | The present invention is based on the finding that CD11b signaling inhibits immune suppression, modulates neovascularization and promotes anti-tumor immune responses in models of murine and human cancer. As such, provided herein are methods of treating cancer using an antibody, protein or small molecule that modulates CD11b activity or expression. Also provided are methods of identifying cancer that is amenable to such treatment and/or increasing susceptibility of cancer cells to treatment with a chemotherapeutic agent. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/058605 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 39/3955 (20130101) A61K 49/0008 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213022 | Strum et al. |
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| FUNDED BY |
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| APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Chapel Hill, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis X. Tavares (Durham, North Carolina) |
| ABSTRACT | This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities. In one aspect, improved treatment of select RB-positive cancers is disclosed using specific compounds disclosed herein. In certain embodiments, the compounds described herein act as highly selective and, in certain embodiments, short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/181638 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/527 (20130101) Original (OR) Class A61K 31/555 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Heterocyclic Compounds C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213023 | Gendelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Howard Gendelman (Omaha, Nebraska); Benson Edagwa (Omaha, Nebraska) |
| ABSTRACT | The present invention provides prodrugs and methods of use thereof. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/301030 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1641 (20130101) A61K 31/5365 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213031 | Boss et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Regents of the university of Colorado (Denver, Colorado) |
| INVENTOR(S) | Gerard Boss (La Jolla, California); Adriano Chan (La Jolla, California); Matthew Brenner (La Jolla, California); Sari Brenner Mahon (La Jolla, California); Vikhyat Bebarta (Denver, Colorado) |
| ABSTRACT | Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 15/734254 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/555 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213041 | Ting et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Miguel N. Rivera (Belmont, Massachusetts); Vikram Deshpande (Belmont, Massachusetts); Kshitij Arora (North Quincy, Massachusetts); Benjamin Dylan Greenbaum (New York, New York); Alexander V. Solovyov (New York, New York) |
| ABSTRACT | Methods for predicting response to immunotherapy and selecting immunotherapy for treating cancer, e.g., cancer of epithelial origin, in a subject. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/967497 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213055 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Irving L. Weissman (Stanford, California); Amira A. Barkal (Stanford, California) |
| ABSTRACT | Methods and compositions are provided for inducing phagocytosis of a target cell in an individual, by blocking the interaction between CD24 on a target cell and Siglec10 on a phagocytic cell. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 15/734470 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 39/39558 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213059 | GEORGIOU et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George GEORGIOU (Austin, Texas); Everett STONE (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
| FILED | Tuesday, August 18, 2020 |
| APPL NO | 16/996806 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 38/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Enzymes C12Y 307/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213067 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Yufang Shi (Belle Mead, New Jersey); Guangwen Ren (Piscataway, New Jersey); Liying Zhang (Belle Mead, New Jersey) |
| ABSTRACT | The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson\'s disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs). |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150457 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/191 (20130101) A61K 38/217 (20130101) A61K 38/2006 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Peptides C07K 14/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213074 | RUVKUN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Gary RUVKUN (Newton, Massachusetts); J. Amaranath GOVINDAN (Somerville, Massachusetts); Elamparithi JAYAMANI (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions comprising a bacterium or a metabolite thereof for enhancing mitochondrial and/or peroxisomal function. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/196271 |
| CURRENT CPC | Fodder A23K 10/18 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/52 (20130101) A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/0056 (20130101) A61K 35/74 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/0006 (20130101) C12N 9/0055 (20130101) C12N 9/0057 (20130101) C12N 2500/14 (20130101) C12N 2500/16 (20130101) C12N 2500/34 (20130101) Enzymes C12Y 101/99 (20130101) C12Y 110/0301 (20130101) C12Y 110/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213098 | Yang |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tianxin Yang (Salt Lake City, Utah) |
| ABSTRACT | Disclosed are methods of treating obesity or an obesity-related condition comprising administering an effective amount of soluble (pro)renin receptor (sPRR) to a subject that is obese or having an obesity-related condition. In some instances, obesity-related conditions can be, but are not limited to, steatosis, hyperglycemia, insulin resistance, chronic renal disease. Disclosed are methods of reducing body weight comprising administering an effective amount of sPRR to a subject in need thereof. Disclosed are methods of treating fatty liver in a subject comprising administering an effective amount of sPRR to a subject in need thereof. Disclosed are methods of treating a fluid and electrolyte disorder comprising administering an effective amount of sPRR to a subject diagnosed with a fluid and electrolyte disorder. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 16/492457 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213101 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070596 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 49/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213110 | Holers et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of The University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | V. Michael Holers (Denver, Colorado); Nirmal Banda (Aurora, Colorado); Liudmila Kulik (Denver, Colorado) |
| ABSTRACT | The present invention provides delivery methods and constructs for treating inflammatory diseases in an individual. The targeted delivery approach utilizes an antibody that recognizes an epitope found to be present at sites of inflammation. The antibody is used to deliver a MAp44 polypeptide or fragment thereof to sites of inflammation, where it inhibits the lectin pathway of complement activation. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113612 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/482 (20130101) Original (OR) Class Peptides C07K 16/18 (20130101) C07K 16/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6424 (20130101) C12N 2710/10041 (20130101) Enzymes C12Y 304/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213126 | Shalek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Pittsburgh - Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander K. Shalek (Cambridge, Massachusetts); Travis Hughes (Cambridge, Massachusetts); Marc H. Wadsworth (Cambridge, Massachusetts); Robert Seder (Bethesda, Maryland); Mario Roederer (Bethesda, Maryland); Joanne L. Flynn (Pittsburgh, Pennsylvania); Patricia Darrah (Bethesda, Maryland) |
| ABSTRACT | Provided herein are compositions and methods for therapeutic and/or prophylactic treatment of an intracellular bacterial infection in a subject in need thereof, comprising one or more modulating agents, wherein the one or more modulating agents increase expression of IFNγ, IL-2, TNF, and/or IL-17 in systemic and/or lung T cells. In some embodiments, the increase of expression of IFNγ, IL-2, TNF, and/or IL-17 occurs in lung T cells. The lung T cells can be lung resident T cells or systemic T cells that are recruited to the lung. In some embodiments, the T cells are CD4+ and/or CD8+ T cells. In some embodiments, the intracellular bacterial infection is a Mycobacterium tuberculosis (MTB) infection. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/137481 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213134 | HEIFETZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | ORPRO THERAPEUTICS, INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter B. HEIFETZ (San Diego, California); Haim MOSKOWITZ (San Diego, California) |
| ABSTRACT | The present invention is related to a drug delivery composition that includes a thioredoxin homologue protein having an N-terminal monocysteinic active site, with the cysteine residue of the active site in a reduced state and an active agent conjugated to the thioredoxin homologue protein and methods of making and using the composition. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/056151 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/407 (20130101) A61K 31/427 (20130101) A61K 31/431 (20130101) A61K 31/475 (20130101) A61K 31/496 (20130101) A61K 31/546 (20130101) A61K 31/665 (20130101) A61K 31/675 (20130101) A61K 31/704 (20130101) A61K 31/5383 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 33/243 (20190101) A61K 38/07 (20130101) A61K 38/12 (20130101) A61K 38/13 (20130101) A61K 38/14 (20130101) A61K 47/64 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213137 | Ekker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen C. Ekker (Rochester, Minnesota); Debabrata Mukhopadhyay (Jacksonville, Florida); Priyabrata Mukherjee (Edmond, Oklahoma); Victoria M. Bedell (Philadelphia, Pennsylvania); Luke H. Hoeppner (Austin, Minnesota); Stella P. Hartono (Houston, Texas) |
| ABSTRACT | This document relates to materials and methods for administering (e.g., topically administering) one or more vascular endothelial growth factor (VEGF) inhibitors to reduce and/or treat ultraviolet (UV)-induced skin injury. For example, compositions including one or more VEGF inhibitors that can be administered (e.g., topically administered) to a mammal to reduce and/or treat UV-induced skin injury following UV exposure are provided. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153565 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 47/6845 (20170801) Original (OR) Class A61K 47/6929 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) A61P 35/00 (20180101) Peptides C07K 16/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213139 | Lu |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Quan Lu (Newton, Massachusetts) |
| ABSTRACT | Methods, systems, compositions and strategies for the delivery of RNA into cells in vivo, ex vivo, or in vitro via ARMMs are provided. In some aspects, ARMMs containing fusion proteins of ARRDC1 fused to an RNA binding protein or an RNA binding protein fused to a WW domain are provided. In some aspects, ARMMs containing binding RNAs associated with cargo RNAs are provided. In other aspects, cargo RNAs associated with a binding RNA, such as a TAR element, are loaded into ARMMs via ARRDC1 fusion proteins containing an RNA binding protein, such as trans-activator of transcription (Tat) protein. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 16/338969 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) A61K 47/54 (20170801) A61K 47/62 (20170801) A61K 47/6901 (20170801) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 2740/16322 (20130101) C12N 2795/10222 (20130101) C12N 2795/10322 (20130101) C12N 2795/18122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213170 | Taboas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Juan M. Taboas (Pittsburgh, Pennsylvania); Alejandro Jose Almarza (Pittsburgh, Pennsylvania); Jingming Chen (Chicago, Illinois) |
| ABSTRACT | Biomaterials disclosed herein can comprise a hydrogel comprising PEG, gelatin, and a glycosaminoglycan with sulfated moiety; and chondrogenic, osteogenic, and immunomodulatory cytokines; wherein the biomaterial is capable of potentiating bone regeneration in a compromised wound while reducing inflammatory response. The glycosaminoglycan with sulfated moiety can comprise heparin, heparan sulfate, keratin sulfate, chondroitin sulfate, dermatan sulfate, and/or similar materials. The biomaterial can further comprise mesenchymal stem cells (MSCs), a crosslinking initiator, microparticles and nanoparticles, and or other materials. The biomaterial can be injectable into a wound, or the biomaterial can be loaded in, or further comprise a porous scaffold providing mechanical support for other components of the biomaterial, such that it can be implanted into a wound. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 17/055046 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 27/3847 (20130101) Original (OR) Class A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213171 | CHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher S. CHEN (Newton, Massachusetts); Jan D. BARANSKI (Philadelphia, Pennsylvania); Ritika CHATURVEDI (Philadelphia, Pennsylvania); Michael T. YANG (West Windsor, New Jersey); Kelly R. STEVENS (Seattle, Washington); Sangeeta N. BHATIA (Lexington, Massachusetts) |
| ABSTRACT | The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213423 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/40 (20130101) A61L 27/50 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 27/3886 (20130101) A61L 2430/20 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213173 | BHATIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sangeeta N. BHATIA (Lexington, Massachusetts); Kelly R. STEVENS (Seattle, Washington); Christopher S. CHEN (Newton, Massachusetts) |
| ABSTRACT | Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213436 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3886 (20130101) A61L 27/3891 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213174 | Spiller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kara Lorraine Spiller (Glenside, Pennsylvania); Nathan Tessema Ersumo (Philadelphia, Pennsylvania) |
| ABSTRACT | This application relates to biologically compatible porous cartilage templates for in vitro and in vivo generation of bone with enhanced structural characteristics. Provided herein are compositions having an internal structure desirable for the generation and regeneration of bone, along with methods of preparation and use. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214159 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/44 (20130101) A61F 2/46 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/222 (20130101) A61L 27/3834 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/04 (20130101) C09D 11/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213181 | Khademhosseini et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women\'s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ali Khademhosseini (Cambridge, Massachusetts); Guillermo Ulises Ruiz Esparza Herrera (Cambridge, Massachusetts); Xichi Wang (Brighton, Massachusetts); Su Ryon Shin (Brookline, Massachusetts); Thomas Jozefiak (Belmont, Massachusetts) |
| ABSTRACT | The present application relates to shear thinning hydrogel compositions which are useful for reducing and/or preventing tissue adhesion in a subject (e.g., a post-operative subject). Methods of using the compositions and kits comprising the compositions oar also provided. |
| FILED | Wednesday, May 29, 2019 |
| APPL NO | 17/058224 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/128 (20130101) A61L 31/145 (20130101) Original (OR) Class A61L 2400/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213200 | Raskin et al. |
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| FUNDED BY |
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| APPLICANT(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward B. Raskin (Irvine, California); David Chi-Wai Lim (Irvine, California); Michael J. Rosinko (Anaheim, California); Firas H. El-Khatib (Allston, Massachusetts); Edward R. Damiano (Acton, Massachusetts) |
| ABSTRACT | An automated blood glucose control system is configured to generate a backup therapy protocol comprising insulin therapy instructions derived from autonomously determined doses of insulin. The system generates a dose control signal using a control algorithm configured to autonomously determine doses of insulin to be infused into a subject for the purpose of controlling blood glucose of the subject based at least in part on a glucose level signal received from a glucose sensor. The system can track insulin therapy administered to the subject over a tracking period, including storing an indication of the autonomously determined doses of insulin delivered to the subject as basal insulin, as correction boluses of insulin, or as mealtime boluses of insulin. The system can generate a backup injection therapy protocol or a backup pump therapy protocol with insulin therapy instructions based at least in part on the insulin therapy administered to the subject over the tracking period. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212984 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2205/52 (20130101) A61M 2230/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213203 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | iRenix Medical, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen J. Smith (Palo Alto, California); Thomas W. Chalberg, JR. (Palo Alto, California) |
| ABSTRACT | Therapeutic agent delivery devices are provided. Aspects of the devices include a syringe that is not surface sterilized, a tip that includes a sterile tissue contacting surface and a needle operably coupled to the syringe and the tip. Also provided are methods of using the devices. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/254514 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/002 (20130101) A61M 5/315 (20130101) Original (OR) Class A61M 5/3202 (20130101) A61M 2005/3126 (20130101) A61M 2210/0612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213306 | Chalasani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Sreekanth H. Chalasani (La Jolla, California); Stuart Ibsen (La Jolla, California) |
| ABSTRACT | The invention provides compositions featuring TRP-4 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRP-4 polypeptide in neurons and other cell types using ultrasound. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/029143 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0033 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213329 | Wechsler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emily Wechsler (Dallas, Texas); Ryan Halter (Lyme, New Hampshire); John A. Batsis (Hanover, New Hampshire) |
| ABSTRACT | Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170). |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/055412 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00043 (20130101) A63B 21/0552 (20130101) A63B 21/4035 (20151001) A63B 24/0062 (20130101) Original (OR) Class A63B 2220/17 (20130101) A63B 2220/51 (20130101) A63B 2220/62 (20130101) A63B 2220/833 (20130101) A63B 2225/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213413 | SALIGRAMA et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Naresha SALIGRAMA (Stanford, California); Ansuman SATPATHY (Stanford, California); Howard Y. CHANG (Stanford, California); Mark M. DAVIS (Stanford, California) |
| ABSTRACT | Provided are systems and methods that can combine T cell receptor sequencing (TCRseq) and Assay for Transposase Accessible Chromatin using sequencing (ATAC-seq), and/or respective aspects thereof. Further provided are systems and methods that can combine ATAC-seq and perturbation sequencing (Perturb-seq), and/or respective aspects thereof. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/967402 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00596 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213673 | Benam et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Kambez Benam (Denver, Colorado); Alexander Kaiser (Keenesburg, Colorado) |
| ABSTRACT | A bioprinter for manufacturing an organomimetic device includes at least one extruder configured to extrude a material, a three-dimensional movement assembly, and a build-plate mounted to the three-dimensional movement assembly. The build-plate may be configured to support the organomimetic device being manufactured. The bioprinter may further include a controller operably coupled to and configured to control the at least one extruder, the three-dimensional movement assembly, and the build-plate. The at least one extruder may be non-movably fixed to the cabinet. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/967395 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/232 (20170801) B29C 64/236 (20170801) B29C 64/245 (20170801) B29C 64/393 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214222 | Kondiboyina et al. |
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| FUNDED BY |
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| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vineel Kondiboyina (Somerville, Massachusetts); Christopher Miles (Acton, Massachusetts); Gregory W. Hall (Belmont, Massachusetts); Simon E. Kozin (Lexington, Massachusetts); Wolfgang Scholz (Beverly, Massachusetts); Frank Heirtzler (Londonderry, New Hampshire) |
| ABSTRACT | Systems, methods and devices for nitric oxide generation are provided for use with various ventilation and/or medical devices and having a humidity control system associated therewith. In some embodiments, a system for generating nitric oxide comprises at least one pair of electrodes configured to generate a product gas containing nitric oxide from a reactant gas, a scrubber configured to remove nitric dioxide NO2 from the product gas, and a humidity control device configured to alter a water content of at least one of the reactant gas and the product gas to control humidity within the system. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146468 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214235 | Ramachandran et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roshini Ramachandran (West Hollywood, California); Jessica K. Logan (Los Angeles, California); Alexander M. Spokoyny (Los Angeles, California) |
| ABSTRACT | A method of making boron oxide nanoparticles. The method can comprise sonochemically treating a composition comprising a boron oxide to form boron oxide nanoparticles. The method allows for the formation of these nanoparticles from non-toxic, inexpensive reagents and ambient reaction conditions. Additionally, the nanoparticles produced by the teachings described herein can be easily surface functionalized. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 15/734106 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 35/1027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214348 | Kamenecka et al. |
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| FUNDED BY |
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| APPLICANT(S) | ASTRAZENECA AB (Sodertalje, Sweden); EOLAS THERAPEUTICS, INC. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Theodore M. Kamenecka (Palm Beach Gardens, Florida); Jörg Holenz (Bolton, Massachusetts); Steven Wesolowski (Natick, Massachusetts); Yuanjun He (Palm Beach Gardens, Florida); Roland Bürli (Hertfordshire, United Kingdom) |
| ABSTRACT | The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116773 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214360 | Petrukhin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Troy, New York); Graham Johnson (Sanbornton, New Hampshire); Rando Allikmets (Cornwall on Hudson, New York); Emily Freeman (Voorheesville, New York); Ping Chen (Slingerlands, New York); Michael Conlon (Schenectady, New York); Lei Zhu (Glenmont, New York) |
| ABSTRACT | The present invention provides a compound having the structure:
|
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099231 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214365 | FISHER et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul B. FISHER (Henrico, Virginia); Maurizio PELLECCHIA (Riverside, California); Swadesh K. DAS (Richmond, Virginia); Timothy P. KEGELMAN (Richmond, Virginia); Bainan WU (Richmond, Virginia); Surya K. DE (Richmond, Virginia); Jun WEI (La Jolla, California); Mitchell E. MENEZES (Richmond, Virginia); Luni EMDAD (Richmond, Virginia) |
| ABSTRACT | Provided herein are, inter alia, compositions that bind to a PDZ1 domain of MDA-9/Syntenin (syndecan binding protein: SDCBP), thereby inhibiting MDA-9/Syntenin activity, and methods of use of same. The compositions and methods provided herein are useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/148813 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 495/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214368 | Pluth et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael D. Pluth (Eugene, Oregon); Yu Zhao (Springfield, Oregon); Matthew M. Cerda (Berkeley, California) |
| ABSTRACT | Disclosed herein are embodiments of a compound that is capable of releasing COS and/or H2S upon reaction with a thiol-containing compound. The compound embodiments also can produce a detectable signal (e.g., a fluorescent signal) substantially concomitantly with COS and/or H2S release and/or can release an active agent, such as a therapeutic agent. Methods of making and using the compound embodiments also are disclosed. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 15/733818 |
| CURRENT CPC | Heterocyclic Compounds C07D 285/01 (20130101) C07D 493/10 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) G01N 33/0044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214378 | Holtzman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Michael J. Holtzman (St. Louis, Missouri); Arthur G. Romero (Chesterfield, Missouri); Benjamin J. Gerovac (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Shamus P. Keeler (University City, Missouri); Kangyun Wu (St. Louis, Missouri) |
| ABSTRACT | Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/059251 |
| CURRENT CPC | Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214390 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jun Liu (Baltimore, Maryland); Jingxin Wang (Baltimore, Maryland); Zufeng Guo (Baltimore, Maryland) |
| ABSTRACT | Compounds with the following structures and their analogs are provided. Compositions that include these structures can be used to inhibit glucose transporters and stop or decrease the proliferation of cancer, treat possible organ rejection and treat autoimmune disease. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 16/074300 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/12 (20130101) A61K 31/167 (20130101) A61K 31/235 (20130101) A61K 31/353 (20130101) A61K 31/407 (20130101) A61K 31/4406 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 5/1008 (20130101) Original (OR) Class C07K 5/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214397 | LY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Danith H. LY (Pittsburgh, Pennsylvania); Srinivas RAPIREDDY (Pittsburgh, Pennsylvania); Bichismita SAHU (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
| FILED | Wednesday, August 26, 2020 |
| APPL NO | 17/003131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214413 | Palmenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ann Carol Palmenberg (Madison, Wisconsin); Kelly Watters (Madison, Wisconsin) |
| ABSTRACT | The present invention provides soluble truncated peptides of CDHR3, recombinant variants thereof and methods of making these peptides. The present invention also provide methods of inhibiting rhinovirus C infection and an in vitro assay for screening for anti-viral agents against rhinovirus C. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/058934 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214415 | Klebanoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| INVENTOR(S) | Christopher A. Klebanoff (New York, New York); Tori N. Yamamoto (Bethesda, Maryland); Nicholas P. Restifo (Bethesda, Maryland) |
| ABSTRACT | The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to a cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)) and a dominant negative Fas polypeptide. In certain embodiments, the cells are antigen-directed and exhibit enhanced cell persistence, and enhanced anti-target treatment efficacy. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214436 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001112 (20180801) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 14/70521 (20130101) C07K 14/70578 (20130101) Original (OR) Class C07K 16/2803 (20130101) C07K 16/2809 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214437 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Irving L. Weissman (Stanford, California); Ravindra Majeti (Palo Alto, California); Arash Ash Alizadeh (San Mateo, California); Mark P. Chao (Mountain View, California) |
| ABSTRACT | Methods are provided for treatment of hematologic cancers, particularly lymphomas and leukemias, including without limitation myelogenous and lymphocytic leukemias. A combination of antibodies specific for CD47; and specific for a cancer associated cell surface marker are administered to the patient, and provide for a synergistic decrease in cancer cell burden. The combination of antibodies may comprise a plurality of monospecific antibodies, or a bispecific or multispecific antibody. Markers of interest include without limitation, CD20, CD22, CD52, CD33; CD96; CD44; CD123; CD97; CD99; PTHR2; and HAVCR2. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150881 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 51/1093 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 16/2887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214442 | BIGNER et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Darell BIGNER (Mebane, North Carolina); Smita NAIR (Cary, North Carolina); Vidyalakshmi CHANDRAMOHAN (Durham, North Carolina) |
| ABSTRACT | Provided is a method of treating a tumor in an individual by neoadjuvant therapy, wherein the individual has not previously undergone a resection of the tumor, the method comprising administering an immunotoxin alone or an immune checkpoint inhibitor and an immunotoxin, such as D2C7-immunotoxin (D2C7-IT), followed by resection of the tumor. The method may further comprise administration of immune checkpoint inhibitor following resection. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/055639 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/243 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214443 | Ghosh et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sankar Ghosh (New York, New York); Yenkel Grinberg-Bleyer (New York, New York) |
| ABSTRACT | Methods of treating a PD-1-resistant cancer are provided and comprise administering to a subject in need thereof a therapeutically effective amount of a c-Rel inhibitor and a therapeutically effective amount of a PD-1 inhibitor. A pharmaceutical combination comprising a therapeutically effective amount of a c-Rel inhibitor, and a therapeutically effective amount of a PD-1 inhibitor is also provided. Finally, methods of treating a cancer such as a CTLA-4-resistant cancer, a CD137-resistant cancer, and an OX-4-resistant cancer are provided and comprise administering to a subject in need thereof a therapeutically effective amount of a c-Rel inhibitor and a therapeutically effective amount of a CLTA-4, CD137 or OX-4 inhibitor, respectively. |
| FILED | Tuesday, January 19, 2021 |
| APPL NO | 17/248308 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214558 | Choi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hak Soo Choi (Needham, Massachusetts); Jonghan Kim (Cambridge, Massachusetts); Georges El Fakhri (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/129380 |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/0025 (20130101) C09B 23/0033 (20130101) C09B 23/0041 (20130101) C09B 23/0066 (20130101) Original (OR) Class C09B 69/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214673 | Jovanovich et al. |
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| FUNDED BY |
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| APPLICANT(S) | S2 Genomics, Inc. (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stevan Bogdan Jovanovich (Livermore, California); Kaiwan Chear (Livermore, California); Bruce Leisz (San Jose, California); David Eberhart (Santa Clara, California); John Bashkin (Fremont, California) |
| ABSTRACT | A system, methods, and apparatus are described to collect and prepare single cells, nuclei, subcellular components, and biomolecules from specimens including tissues and in some embodiments use the single cells to form organoids or microtissues. The system can perform enzymatic and/or physical disruption of the tissue to dissociate it into single-cells and then use a hanging droplet method to form organoids or microtissues. |
| FILED | Saturday, June 01, 2019 |
| APPL NO | 15/734128 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/12 (20130101) C12M 45/02 (20130101) Original (OR) Class C12M 45/06 (20130101) C12M 45/09 (20130101) C12M 45/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/31 (20130101) G01N 1/286 (20130101) G01N 1/4077 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214677 | Lyons et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Lyons (York, Pennsylvania); Christopher Ward (Baltimore, Maryland); Joseph Stains (Laurel, Maryland) |
| ABSTRACT | The present invention relates to a fluid flow device. The device includes an elongate body having a proximal end, a distal end, and a length therebetween, at least one source fluid inflow port, at least one waste fluid outflow port, at least one well inlet port positioned at the distal end of the elongate body, at least one well outlet port positioned at the distal end of the elongate body, at least one conduit connecting the at least one source fluid inflow port to the at least one well inlet port, and at least one conduit connecting the at least one waste fluid outflow port to the at least one well outlet port. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154239 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50853 (20130101) B01L 2200/026 (20130101) B01L 2300/046 (20130101) B01L 2300/0829 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214701 | DESAI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | Encodia, Inc. (San Diego, California) |
| INVENTOR(S) | Kevin DESAI (San Diego, California); Kevin L. GUNDERSON (San Diego, California); Robert C. JAMES (San Diego, California); Lei SHI (San Diego, California); Stephen VERESPY, III (San Diego, California) |
| ABSTRACT | Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/213169 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214708 | BRANON et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tess BRANON (Stanford, California); Alice Y. TING (Stanford, California) |
| ABSTRACT | Engineered promiscuous biotin ligases and methods of using them in proximity labeling are described. In particular, the invention provides novel biotin ligase variants having increased promiscuous biotinylation activity capable of proximity labeling of proteins in live cells in as little as 10 minutes. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/962792 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Original (OR) Class Enzymes C12Y 603/04015 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/6842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214712 | Pakhomova et al. |
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| FUNDED BY |
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| APPLICANT(S) | OLD DOMINION UNIVERSITY RESEARCH FOUNDATION (Norfolk, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olga Pakhomova (Norfolk, Virginia); Andrei G. Pakhomov (Norfolk, Virginia) |
| ABSTRACT | Systems and methods of enhancing membrane permeabilization in a cell are provided. An example method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the systems and methods, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215773 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214722 | Shlomchik et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Shlomchik (Pittsburgh, Pennsylvania); Adriana Turqueti Neves (Olching, Germany); Eduardo Schittler Neves (Olching, Germany); Constantinos George Panousis (Pittsburgh, Pennsylvania); Alexander McIntyre Rowe (Pittsburgh, Pennsylvania) |
| ABSTRACT | This document provides methods and materials involved in cloning functional TCRs from single T cells. For example, methods and materials for obtaining nucleic acid encoding a TCR from a single T cell and arranging that nucleic acid to form nucleic acid vectors successfully designed to express a TCR, kits for obtaining nucleic acid encoding a TCR from a single T cell and arranging that nucleic acid to form nucleic acid vectors successfully designed to express a TCR, methods for making such kits, collections of nucleic acid primers designed to amplify the entire coding sequence of both variable regions for each expressed V segment for functional αβ or γδ TCRs of a particular mammalian species, methods for using such collections of nucleic acid primers to clone functional TCRs from single T cells, and kits containing such collections of nucleic acid primers to clone functional TCRs from single T cells are provided. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/127773 |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/1096 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214724 | CHOUDHARY et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN\'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit CHOUDHARY (Boston, Massachusetts); Donghyun LIM (Cambridge, Massachusetts); Kurt COX (Cambridge, Massachusetts); Soumyashree Ashok GANGOPADHYAY (Boston, Massachusetts) |
| ABSTRACT | The present inventions generally relate to site-specific delivery of nucleic acid modifiers and includes novel DNA-binding proteins and effectors that can be rapidly programmed to make site-specific DNA modifications. The present inventions also provide a synthetic all-in-one genome editor (SAGE) systems comprising designer DNA sequence readers and a set of small molecules that induce double-strand breaks, enhance cellular permeability, inhibit NHEJ and activate HDR, as well as methods of using and delivering such systems. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/758840 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 31/18 (20130101) A61K 31/336 (20130101) A61K 31/655 (20130101) A61K 31/7088 (20130101) A61K 38/465 (20130101) A61K 47/60 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214731 | Scadden et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambrigde, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Cheuk-Him Man (Kowloon, China Hong Kong) |
| ABSTRACT | Disclosed are methods for treating cancers (e.g., AML) having increased intracellular pH, including AML overexpressing MCT4. Also disclosed are methods of modulating cell growth by modulating intracellular pH. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/016209 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/551 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214732 | Close et al. |
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| FUNDED BY |
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| APPLICANT(S) | 490 BioTech, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Close (Knoxville, Tennessee); Steven Ripp (Knoxville, Tennessee); Gary Sayler (Blaine, Tennessee); Michael Conway (Medford, Massachusetts) |
| ABSTRACT | The present disclosure relates to cells, including stem cells, comprising an autobioluminescent phenotype, wherein the cells emit a luminescent signal in the absence of an exogenous luminescent stimulator. The luminescent signal may be constitutive, inducible, repressible, or tissue-specific. The cells express a synthetically engineered bacterial luciferase (lux) cassette, i.e., the luxCDABEfrp gene cassette. The cells may comprise luxA, luxB, luxC, luxD, luxE, and flavin reductase. The cells may each express a combined expression level of luxC, luxD, luxE, and flavin reductase that is from ten to forty times greater than a combined expression level of luxA and luxB. Further, methods of making and using the cells comprising an autobioluminescent phenotype are disclosed herein. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/210131 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 15/64 (20130101) Original (OR) Class C12N 15/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) Enzymes C12Y 105/0103 (20130101) C12Y 114/14003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214734 | Mollapour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehdi Mollapour (Fayetteville, New York); Giorgio Colombo (Pavia, Italy); Mark Woodford (Baldwinsville, New York); Gennady Bratslavsky (Fayetteville, New York); Dimitra Bourboulia (Fayetteville, New York) |
| ABSTRACT | The present disclosure relates to a method of identifying an agent-of-interest that alters binding or activity of a client protein to a chaperone, co-chaperone, or chaperone-co-chaperone complex, the method including: determining a three-dimensional (3D) structure of a client protein-of-interest; evaluating the 3D structure of the client protein-of-interest to identify an unstable substructure of the 3D structure of the client protein-of-interest; and determining an amino acid sequence of the unstable substructure of the 3D structure of the client protein-of-interest to identify an agent-of-interest that alters binding or activity of a client protein to a chaperone, co-chaperone, or chaperone-co-chaperone complex. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099692 |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/70 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214751 | Kaler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Stephen G. Kaler (Bethesda, Maryland) |
| ABSTRACT | Disclosed herein are codon-optimized nucleic acids encoding a reduced-size ATP7A protein. Also disclosed are vectors and recombinant viruses (such as recombinant adeno-associated viruses) including the codon-optimized nucleic acids encoding the reduced-size ATP7A protein and compositions including the disclosed vectors and viruses. Further disclosed herein are methods of treating copper transport disorders, for example by administering a disclosed nucleic acid, vector, or recombinant virus to a subject with a copper transport disorder, such as Menkes disease, occipital horn syndrome, or ATP7A-related distal motor neuropathy. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217961 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/34 (20130101) A61K 38/46 (20130101) A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2800/22 (20130101) Enzymes C12Y 306/03004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214758 | CHATTOPADHYAY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ID GENOMICS, INC. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sujay CHATTOPADHYAY (Kolkata, West Bengal, India); Veronika TCHESNOKOVA (Seattle, Washington); Elena RECHKINA (Seattle, Washington) |
| ABSTRACT | The present disclosure provides methods and compositions for generating clonotypes from input nucleic acid sequences. Presently disclosed clonotype generating methods produce accurate and efficient indicators of genetic relatedness and diversity, including for example, of pathogenic organisms such as infectious bacteria. Also provided are primers, kits, and related methods for determining antibiotic susceptibility of a pathogenic organism, such as, for example, Klebsiella, and for treating an infection by one or more pathogenic Discard organisms on the basis of herein disclosed clonotypes and clonotype-generating methods. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 17/053727 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1089 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/30 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214773 | HE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Chuan HE (Chicago, Illinois); Xiaocheng WENG (Chicago, Illinois); Tong WU (Chicago, Illinois) |
| ABSTRACT | Embodiments are directed to N3-kethoxal reagents and derivatives thereof, and related methods that allow fast and reversible labeling of single-stranded nucleic acids in live cells. By way of example, one aspect is directed to a process for reversible labeling of single-stranded guanine bases in live cells, which results in an effective in vivo method for transcriptome-wide RNA secondary structure mapping and RNA G-quadruplex prediction. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 17/250023 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214778 | Makrigiorgos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerassimos Makrigiorgos (Chestnut Hill, Massachusetts); Cloud P. Paweletz (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are methods to improve the efficiency of absolute quantification of nucleic acid targets such as digital PCR and digital isothermal amplification, and/or reduce the amount of nucleic acid sample required to determine the absolute quantity of target sequences in the sample. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 17/057936 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6848 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214781 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Abhijit Ajit Patel (Madison, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abhijit Ajit Patel (Madison, Connecticut) |
| ABSTRACT | The current document is directed to methods and compositions that enable simplified, sensitive, and accurate quantification of nucleic acids, including sequence variations and epigenetic modifications. Some methods enable highly sensitive measurement of low-abundance nucleic acid variants from a complex mixture of nucleic acid molecules. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/105188 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215471 | Lipson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michal Lipson (New York, New York); Xingchen Ji (New York, New York); Alexander Klenner (New York, New York); Xinwen Yao (Baltimore, Maryland); Yu Gan (Harriston, New Jersey); Alexander L. Gaeta (New York, New York); Christine P Hendon (Bronx, New York) |
| ABSTRACT | A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/100401 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/7257 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215672 | Teitell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. Teitell (Tarzana, California); Thomas A. Zangle (Salt Lake City, Utah); Owen M. Witte (Sherman Oaks, California); Daina Burnes Linton (Marina Del Rey, California) |
| ABSTRACT | In certain embodiments methods of identifying T cell receptors that respond to specific target cell antigens are provided, where the methods comprise providing a substrate bearing a plurality of target cells (e.g., mammalian cells); contacting the target cells on the substrate with CD8+ T cells; and using label-free optical imaging to identify an increase in mass of a T-cell and/or a decrease in mass of a target cell, where an increase in mass of a T cell and/or a decrease in mass of a target cell is an indicator that said T cell bears a T cell receptor activated by antigens presented on said target cell. |
| FILED | Thursday, December 17, 2020 |
| APPL NO | 17/125855 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02015 (20130101) G01B 11/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class G01N 2333/70517 (20130101) Optical Elements, Systems, or Apparatus G02B 21/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215679 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Sogang University (Seoul, South Korea) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ki-Bum Lee (Piscataway, New Jersey); Jin-Ho Lee (Piscataway, New Jersey); Jeong-Woo Choi (Seoul, South Korea); Jin-Ha Choi (Seoul, South Korea) |
| ABSTRACT | Nanorod devices for isolating and characterizing target cellular components are provided. Methods of isolating, detecting, and/or characterizing the components are also provided. Methods of use and treatment are further disclosed, such as treating diseases identified using the nanorods and/or using differentiated stem cells identified using the provided nanorods. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142950 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/533 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/40 (20130101) H01F 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215684 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Scott M. Berry (Madison, Wisconsin) |
| ABSTRACT | A device and a method for isolating a target from a sample are provided. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes a first plate having a first region for receiving at least a portion of the sample. A second plate is spaced from the first plate by a distance and has a first region for receiving a reagent. A force attracts the target bound solid phase substrate toward the first region of the second plate such that the target bound solid phase substrate in the portion of the sample are drawn through the air gap and into the reagent by the force. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/197243 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/5088 (20130101) B01L 2200/16 (20130101) B01L 2300/161 (20130101) B01L 2300/0819 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 1/405 (20130101) G01N 33/54326 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/25375 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215696 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Weiss (Decatur, Georgia); Victor Band (Decatur, Georgia); David Hufnagel (Atlanta, Georgia) |
| ABSTRACT | This disclosure contemplates detecting antimicrobial heteroresistance to guide antibiotic or other antimicrobial therapy. In certain embodiments, this disclosure contemplates avoiding a monotherapy with antibiotics to which an individual bacterial isolate is heteroresistant, because this can lead to treatment failure. Thus, in certain embodiments, one uses a combination of antibiotics to which a bacterium is individually heteroresistant. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214332 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56961 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215700 | Hughes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Hughes (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a soluble protein signature from the tumor microenvironment that can predict overall survival post-surgery in pancreatic adenocarcinoma. The disclosed protein signatures provide a precision approach to surgical therapy for patients with pancreatic cancer. Also disclosed herein is a soluble protein signature from the tumor microenvironment that can diagnose pancreatic ductal adenocarcinoma (PDAC). Also disclosed herein are proteins that can be used to accurately normalize protein levels in a pancreatic sample. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 17/059727 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) Original (OR) Class G01N 33/57484 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215703 | McDevitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John T. McDevitt (New York, New York); Michael P. McRae (Houston, Texas) |
| ABSTRACT | The present disclosure is related to systems and methods to be used as aids in the diagnosis of risk for oral cancer, potentially malignant oral lesion (PMOL), and/or oral epithelial dysplasia (OED) by identifying cellular phenotype characteristics of cell samples, including percentage of mature squamous cells, presence or absence of nuclear actin in mature squamous cells, percentage of non-mature squamous cells, percentage of small round cells, percentage of white blood cells, and percentage of lone nuclei. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/147681 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215706 | MARCOTTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Edward MARCOTTE (Austin, Texas); Eric ANSLYN (Austin, Texas); Jagannath SWAMINATHAN (Austin, Texas); Angela M. BARDO (Austin, Texas); Caroline M. HINSON (Austin, Texas); Cecil HOWARD (Austin, Texas); Brendan FLOYD (Austin, Texas) |
| ABSTRACT | The present disclosure provides methods of selectively label an amino acid residue on a peptide by replacing a post translational modification with a labeling moiety and sequencing the peptide to obtain the location of the amino acid residue and the identity of the post translational modification. In some aspects, the disclosure also provides methods of identifying the position, quantity, the identity of a post translational modification, or any combination thereof, in peptides which may be used for therapeutic purposes. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155298 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6818 (20130101) Original (OR) Class G01N 2440/10 (20130101) G01N 2440/12 (20130101) G01N 2440/14 (20130101) G01N 2440/18 (20130101) G01N 2440/26 (20130101) G01N 2440/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215707 | MARCOTTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward MARCOTTE (Austin, Texas); Eric ANSLYN (Austin, Texas); Alexander BOULGAKOV (Austin, Texas); Angela M. BARDO (Austin, Texas); Siyuan Stella WANG (Austin, Texas); Jagannath SWAMINATHAN (Austin, Texas); Fan TU (Austin, Texas) |
| ABSTRACT | The present disclosure provides methods of identifying and quantifying the peptides displayed by the major histocompatibility complex (MHC). Such methods may comprise the ability to determine the type, identity, and quantity of each peptide displayed by the MHC. In some embodiments, these methods may be used to develop an anti-cancer therapy or type the HLA of a patient. Also provided herein are compositions comprising peptides from the MHC which have been prepared for sequencing. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 17/268162 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6818 (20130101) Original (OR) Class G01N 33/54306 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215708 | Shu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiaokun Shu (San Francisco, California); Qiang Zhang (Daly City, California); Chan-I Chung (San Francisco, California) |
| ABSTRACT | The invention is a novel reporter system for measuring protein-protein interactions. The system uses a pair of functionalized coiled coil subunits that spontaneously form two separate homo-oligomers when expressed in cells. The coiled coil subunits are functionalized with fluorescent proteins and complementary interacting proteins. Upon an activation stimulus which promotes the protein-protein interaction, the interacting proteins drive the formation of multivalent aggregates of the homo-oligomers in phase-shifted droplets. The highly concentrated fluorescent proteins in these structures provide high brightness over background fluorescence and a readily observed, quantitative and dynamic indicator of the protein-protein interaction. The reporters and assay methods are amenable to cells and whole organisms. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/838023 |
| CURRENT CPC | Peptides C07K 14/4705 (20130101) C07K 14/4746 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 9/0028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215720 | O\'Bryant |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Texas Health Science Center at Fort Worth (Fort Worth, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sid E. O\'Bryant (Aledo, Texas) |
| ABSTRACT | The present disclosure relates to a method of treating a subject having a proinflammatory endophenotype profile with celecoxib or naproxen to improve cognition or to prevent cognitive decline or dysfunction in the subject. In another aspect, the present disclosure relates to a method of screening a subject for inclusion an NSAID or a PPAR-γ agonist clinical trial. In another aspect, the present disclosure relates to a method of determining a surrogate outcome of an NSAID or a PPAR-γ agonist clinical trial. In yet another aspect, the present disclosure relates to a method of treating an Alzheimer\'s disease patient having both a proinflammatory endophenotype profile and a metabolic endophenotype profile with a PPAR-γ agonist to improve cognition or to prevent cognitive decline or dysfunction in the patient. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193907 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216351 | Chaterji et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Somali Chaterji (West Lafayette, Indiana); Saurabh Bagchi (West Lafayette, Indiana); Ashraf Mahgoub (West Lafayette, Indiana) |
| ABSTRACT | A system may forecast a workload for a cluster of nodes in a database management system. The system may generate a reconfiguration plan based on the forecasted workload. The system may obtain a heterogenous configuration set. The heterogenous configuration set may include respective configuration sets for the complete sets of nodes. The system may forecast, based on a first machine learning model, respective performance metrics for nodes in each of the complete sets. The system may forecast a cluster performance metric for the entire cluster of nodes based on a second machine learning model. The system may include, in response to satisfaction of an acceptance criterion, the heterogenous configuration set in the reconfiguration plan. The system may cause the cluster of nodes to be reconfigured based on the reconfiguration plan. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/139958 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3891 (20130101) G06F 9/44505 (20130101) G06F 9/45558 (20130101) Original (OR) Class G06F 16/182 (20190101) G06F 2009/4557 (20130101) G06F 2009/45583 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217213 | Cole et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elizabeth K. Cole (Stanford, California); Shreyas S. Vasanawala (Stanford, California); Frank Ong (Los Altos, California); John M. Pauly (Stanford, California) |
| ABSTRACT | A method of magnetic resonance imaging acquires undersampled MRI data and generates by an adversarially trained generative neural network MRI data having higher quality without using any fully-sampled data as a ground truth. The generative neural network is adversarially trained using a discriminative neural network that distinguishes between undersampled MRI training data and candidate undersampled MRI training data produced by applying an MRI measurement function containing an undersampling mask to generated MRI training data produced by the generative neural network from the undersampled MRI training data. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/740655 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 5/10 (20130101) G06T 11/006 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217490 | MISHRA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (, None) |
| INVENTOR(S) | Bhubaneswar MISHRA (Great Neck, New York); Giuseppe NARZISI (New York, New York) |
| ABSTRACT | Exemplary methods, procedures, computer-accessible medium, and systems for base-calling, aligning and polymorphism detection and analysis using raw output from a sequencing platform can be provided. A set of raw outputs can be used to detect polymorphisms in an individual by obtaining a plurality of sequence read data from one or more technologies (e.g., using sequencing-by-synthesis, sequencing-by-ligation, sequencing-by-hybridization, Sanger sequencing, etc.). For example, provided herein are exemplary methods, procedures, computer-accessible medium and systems, which can include and/or be configured for obtaining raw output from a sequencing platform configured to be used for reading fragment(s) of genomes, obtaining reference sequences for the genomes obtained independently from the raw output, and generating a base-call interpretation and/or alignment using the raw output and the reference sequences. For example, a score function can be determined based on information associated with the sequencing platform that can be used to analyze polymorphisms based on the base-call interpretation and/or alignment. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/216000 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218485 | KOVACH |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (IOWA CITY, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CHRISTOPHER K. KOVACH (IOWA CITY, Iowa) |
| ABSTRACT | The invention addresses the problem of recovering an unknown signal from multiple records of brief duration which are presumed to contain the signal at mutually random delays in a background of independent noise. The scenario is relevant to many applications, among which are the recovery of weak transients from large arrays of sensors and the identification of recurring patterns through a comparison of sequential intervals within a single record of longer duration. A simple and practical approach is provided by solving this problem through higher-order spectra is developed. Applying the method to the third-order spectrum, the bispectrum, leads to filters derived from cross bicoherence. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 17/058727 |
| CURRENT CPC | Transmission H04B 7/0842 (20130101) H04B 17/318 (20150115) H04B 17/336 (20150115) H04B 17/364 (20150115) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218998 | Ong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frank Ong (Los Altos, California); John M. Pauly (Stanford, California); Shreyas S. Vasanawala (Stanford, California); Michael Lustig (Moraga, California); Nien Sin Cedric Yue Sik Kin (San Carlos, California) |
| ABSTRACT | A method of medical imaging includes performing a medical imaging scan to produce acquired imaging data; reconstructing from the acquired imaging data a multi-dimensional medical imaging dataset in the form of a sliceable compressed representation where the reconstruction does not at any stage create full decompressed images; and producing from the sliceable compressed representation a selected image slice by decompressing only a subset of the sliceable compressed representation. The sliceable compressed representation may be stored in a lossless format, and the selected image slice may be displayed on a viewer for visualization. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146355 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 19/63 (20141101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20210213101 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070596 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 49/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213115 | PEOPLES |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George E. PEOPLES (Spring Branch, Texas) |
| ABSTRACT | Provided are methods for inducing and maintaining protective immunity against a tumor expressing FRα in a subject, comprising the administration of one or more peptide vaccines according to a particular dosages or particular dosage regimens. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/101985 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213159 | Kudela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Damien Kudela (Santa Barbara, California); Galen D. Stucky (Santa Barbara, California); Anna May-Masnou (Barcelona, Spain); Gary Bernard Braun (San Diego, California); James H. Morrissey (Champaign, Illinois); Stephanie A. Smith (Urbana, Illinois) |
| ABSTRACT | A hemostatic composition is provided. The hemostatic composition includes a hemostatically effective amount of a hemostatic agent that includes a nanoparticle and a polyphosphate polymer attached to the nanoparticle. Also provided are medical devices and methods of use to promote blood clotting. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099400 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/595 (20170801) A61K 47/6923 (20170801) A61K 47/6935 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 2300/404 (20130101) A61L 2300/418 (20130101) A61L 2400/04 (20130101) A61L 2400/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213170 | Taboas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Juan M. Taboas (Pittsburgh, Pennsylvania); Alejandro Jose Almarza (Pittsburgh, Pennsylvania); Jingming Chen (Chicago, Illinois) |
| ABSTRACT | Biomaterials disclosed herein can comprise a hydrogel comprising PEG, gelatin, and a glycosaminoglycan with sulfated moiety; and chondrogenic, osteogenic, and immunomodulatory cytokines; wherein the biomaterial is capable of potentiating bone regeneration in a compromised wound while reducing inflammatory response. The glycosaminoglycan with sulfated moiety can comprise heparin, heparan sulfate, keratin sulfate, chondroitin sulfate, dermatan sulfate, and/or similar materials. The biomaterial can further comprise mesenchymal stem cells (MSCs), a crosslinking initiator, microparticles and nanoparticles, and or other materials. The biomaterial can be injectable into a wound, or the biomaterial can be loaded in, or further comprise a porous scaffold providing mechanical support for other components of the biomaterial, such that it can be implanted into a wound. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 17/055046 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 27/3847 (20130101) Original (OR) Class A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213191 | BRUGGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| ASSIGNEE(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| INVENTOR(S) | James M. BRUGGER (Newburyport, Massachusetts); David DESOUZA (Essex, Massachusetts) |
| ABSTRACT | Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/218860 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3629 (20140204) A61M 1/3643 (20130101) Original (OR) Class A61M 1/3644 (20140204) A61M 1/3646 (20140204) A61M 1/3652 (20140204) A61M 1/3672 (20130101) A61M 39/10 (20130101) A61M 2205/702 (20130101) A61M 2205/705 (20130101) A61M 2205/707 (20130101) A61M 2205/3331 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213523 | Peterson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | G. P. "Bud" Peterson (Atlanta, Georgia); Haiping Hong (Rapid City, South Dakota) |
| ABSTRACT | Disclosed herein is a method of homogeneously mixing solids, comprising: mixing, in a fluid medium, at least a first Got nanoparticle material and a surfactant, wherein the surfactant causes the first nanoparticle material to distribute uniformly in the fluid medium and have a specific charge; adding, to the fluid medium, a second nanoparticle material, wherein the surfactant has a charge of opposite polarity to the zeta potential of the second nanoparticle material; attaching the second nanoparticle material to the first Nnanoparticle material using the charge attraction of the surfactant and the second nanoparticle material to obtain a homogeneous material; and removing the attached first and second nanoparticle materials from the fluid medium to obtain a solid homogeneous material. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054202 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) Original (OR) Class B22F 1/0074 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214101 | Hoffman |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nolan R. Hoffman (Vicksburg, Mississippi) |
| ABSTRACT | In one embodiment, tie-down assembly is provided for securing a parked aircraft to a slab of an aircraft mooring area. The assembly includes a support structure having a first side wall, a second side wall, a first end cover coupled with the first side wall and the second side wall, and a second end cover coupled with the first side wall and the second side wall. The assembly also includes a connector rod coupled with the first side wall and the second side wall, a talon pivot rod coupled with the first side wall and the second side wall, a first talon rotatably coupled with the talon pivot rod, a second talon rotatably coupled with the talon pivot rod, a first depth adjustment mechanism coupled with the first talon, and a second depth adjustment mechanism coupled with the second talon. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742841 |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214303 | ZARE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (Cludad de Mexico, Coyacan, Mexico); INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN (Cludad de Mexico, Alcaldia Tlalpan, Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Neil ZARE (Stanford, California); Jose Ignacio VEYTIA-BUCHELI (San Luis Potosi, Mexico); Edson Norberto Carcamo NORIEGA (Cuernavaca, Mexico); Gnanamani ELUMALAI (Stanford, California); Shyam SATHYAMOORTHI (Stanford, California); Lourival Domingos POSSANI POSTAY (Cuernavaca, Mexico); Shibdas BANERJEE (Howrah, India); Rogelio Enrique HERNANDEZ PANDO (Ciudad de Mexico, Mexico) |
| ABSTRACT | Provided are colored 1,4-benzoquinone compounds obtained by oxidation of precursor molecules from the venom of the scorpion Diplocentrus melici (Diplocentridae family). Schemes for the chemical synthesis of these compounds using reagents commercially available are also provided. Biological assays show that the red compound (3,5-dimethoxy-2-(methylthio)cyclohexa-2,5-diene-1,4-dione) is very effective at killing Staphylococcus aureus and that the blue compound (5-methoxy-2,3-bis(methylthio)cyclohexa-2,5-diene-1,4-dione) has remarkable activity against Mycobacterium tuberculosis. The blue compound is effective against multi-drug-resistant tuberculosis (MDR-TB) and is not detrimental to lung epithelium. Both compounds were found to be cytotoxic to human neoplastic cell lines and to mononuclear cells (PBMCs). |
| FILED | Monday, May 20, 2019 |
| APPL NO | 17/058962 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 319/20 (20130101) C07C 323/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214469 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xi Chen (New York, New York); Rein V. Ulijn (New York, New York); Zhi-Lun Liu (New York, New York); Yi-Ren Wang (San Jose, California); Daniela Kroiss (New York, New York); Haozhen Wang (New York, New York) |
| ABSTRACT | A rotary engine that generates electricity using differences in relative humidity. A water-responsive material expands and contracts as water evaporates which drives the rotation of two wheels. The rotary motion drives an electrical generator which produces electricity. In another embodiment, the water-responsive material is used to actuate an artificial muscle of a robotic device. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214132 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0015 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0081 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 105/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214505 | WAGENER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth B. WAGENER (Gainesville, Florida); Taylor W. GAINES (Chandler, Arizona); Michael BELL (North East, Maryland); Julia Grace PRIBYL (Gainesville, Florida) |
| ABSTRACT | A polysulfone has sulfone units that are separated by alkylene units in a polymer chain or a copolymer chain where the alkylene units have at least four carbons between sulfone units. The alkylene units can include an ethenylene unit separated from the sulfone units by at least one methylene units. The polysulfones can be crosslinked for enhanced thermal stability. Membranes can be formed from the polysulfones. |
| FILED | Tuesday, January 19, 2021 |
| APPL NO | 17/152164 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/22 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214664 | RAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (BALTIMORE, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | GOVIND RAO (ELLICOTT CITY, Maryland); YORDAN KOSTOV (COLUMBIA, Maryland); ABHAY ANDAR (GAITHERSBURG, Maryland); MUSTAFA AL-ADHAMI (SILVER SPRING, Maryland) |
| ABSTRACT | The present invention provides for a fully integrated microfluidic system capable of producing single-dose amounts of biotherapeutics at the point-of-care wherein protein production, purification and product harvest are all integrated as a single microfluidic device which is portable and capable of continuous-flow production of biotherapeutics at the microscale using a cell-free reaction system. |
| FILED | Thursday, June 07, 2018 |
| APPL NO | 16/618473 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/44 (20130101) C12M 27/00 (20130101) C12M 29/20 (20130101) C12M 33/14 (20130101) C12M 41/12 (20130101) C12M 41/26 (20130101) C12M 41/28 (20130101) C12M 41/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214698 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); John Paul Guilinger (Cambridge, Massachusetts); David B. Thompson (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure provide compositions, methods, and kits for improving the specificity of RNA-programmable endonucleases, such as Cas9. Also provided are variants of Cas9, e.g., Cas9 dimers and fusion proteins, engineered to have improved specificity for cleaving nucleic acid targets. Also provided are compositions, methods, and kits for site-specific nucleic acid modification using Cas9 fusion proteins (e.g., nuclease-inactivated Cas9 fused to a nuclease catalytic domain or a recombinase catalytic domain). Such Cas9 variants are useful in clinical and research settings involving site-specific modification of DNA, for example, genomic modifications. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103233 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/465 (20130101) Peptides C07K 14/315 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/1241 (20130101) C12N 15/01 (20130101) C12N 15/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214713 | Bashor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Caleb J. Bashor (Boston, Massachusetts); Jason Hung-Ying Yang (Watertown, Massachusetts); Arnaud Gutierrez (Somerville, Massachusetts); Wooseok Steven Ahn (Tenafly, New Jersey); James J. Collins (Newton, New Jersey); Brandon Gei-Chin Wong (Brighton, Massachusetts); Ahmad S. Khalil (Lexington, Massachusetts) |
| ABSTRACT | Disclosed herein are a high-throughput continuous culture system and novel methodologies for the experimental evolution of natural and synthetic microbes using the continuous culture system. The microbial culture is exposed to a stress ramp function which is overlaid on top of a culture fitness function. The amount of stress applied to the culture is increased in response to increased fitness of the microbial culture. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 16/081975 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/01 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214724 | CHOUDHARY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN\'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit CHOUDHARY (Boston, Massachusetts); Donghyun LIM (Cambridge, Massachusetts); Kurt COX (Cambridge, Massachusetts); Soumyashree Ashok GANGOPADHYAY (Boston, Massachusetts) |
| ABSTRACT | The present inventions generally relate to site-specific delivery of nucleic acid modifiers and includes novel DNA-binding proteins and effectors that can be rapidly programmed to make site-specific DNA modifications. The present inventions also provide a synthetic all-in-one genome editor (SAGE) systems comprising designer DNA sequence readers and a set of small molecules that induce double-strand breaks, enhance cellular permeability, inhibit NHEJ and activate HDR, as well as methods of using and delivering such systems. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/758840 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 31/18 (20130101) A61K 31/336 (20130101) A61K 31/655 (20130101) A61K 31/7088 (20130101) A61K 38/465 (20130101) A61K 47/60 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214776 | Henley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Hampton Henley (Chapel Hill, North Carolina); Elizabeth Ann Dethoff (Chapel Hill, North Carolina); John Michael Ramsey (Chapel Hill, North Carolina) |
| ABSTRACT | Provided are compounds, compositions, kits, systems, devices, and methods for improving an assay such as, for example, a multiplexed PCR assay (e.g., a multiplexed immuno-PCR assay). A solid support (e.g., a bead) may be provided according to some embodiments of the present invention. The solid support may comprise an encoding agent (e.g., a dye), a nucleic acid sequence (e.g., an oligonucleotide and/or primer); and a molecular recognition element (e.g., an antibody). A detection reagent may be provided according to some embodiments of the present invention. The detection reagent may comprise a molecular recognition element (e.g., an antibody) and a nucleic acid tag. In some embodiments, at least a portion of the nucleic acid sequence of the solid support and at least a portion of the nucleic acid target tag of the detection reagent are configured to participate in a nucleic acid amplification process. A solid support and detection reagent may bind to the same target, thereby forming a reagent pair. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 17/048115 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214856 | Grotjohn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy A. Grotjohn (Okemos, Michigan); Ramon Diaz (East Lansing, Michigan); Aron Hardy (East Lansing, Michigan) |
| ABSTRACT | The disclosure relates to large area single crystal diamond (SCD) surfaces and substrates, and their methods of formation. Typical large area substrates can be at least about 25 mm, 50 mm, or 100 mm in diameter or square edge length, and suitable thicknesses can be about 100 μm to 1000 μm. The large area substrates have a high degree of crystallographic alignment. The large area substrates can be used in a variety of electronics and/or optics applications. Methods of forming the large area substrates generally include lateral and vertical growth of SCD on spaced apart and crystallographically aligned SCD seed substrates, with the individual SCD growth layers eventually merging to form a composite SCD layer of high quality and high crystallographic alignment. A diamond substrate holder can be used to crystallographically align the SCD seed substrates and reduce the effect of thermal stress on the formed SCD layers. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/055943 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 25/08 (20130101) C30B 25/12 (20130101) C30B 25/16 (20130101) C30B 25/20 (20130101) C30B 25/025 (20130101) Original (OR) Class C30B 29/04 (20130101) C30B 29/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215168 | Greene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Britton Greene (East Hartford, Connecticut); Dustin Joseph Frohnapfel (Bloomfield, Connecticut) |
| ABSTRACT | A boost compressor assembly may comprise an outer annular structure and a plurality of blades. Each blade in the plurality of blades may be moveably coupled to the outer annular structure. The plurality of blades may be configured to deploy in response to the boost compressor assembly rotating. The plurality of blades may be configured to retract when the boost compressor assembly stops rotating. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742591 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 7/02 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Non-positive-displacement Pumps F04D 29/366 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215235 | O\'BRIEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin W. O\'BRIEN (Ithaca, New York); Robert F. SHEPHERD (Ithaca, New York) |
| ABSTRACT | A transmission is presented, including a spool having a bore. An outer member disposed on the spool, and a cord is configured to at least partially wrap around the outer member. The outer member is configured to constrict and unconstrict to a force applied to the outer member. In this way, rotation of the spool causes a tension force to be applied to the cord, and a greater tension force in the cord will cause the outer member to constrict more than a lower tension force in the cord. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/648610 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/104 (20130101) Gearing F16H 19/08 (20130101) Original (OR) Class F16H 55/54 (20130101) F16H 2019/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215461 | Hoemann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John M. Hoemann (Vicksburg, Mississippi); Justin M. Roberts (Florence, Mississippi) |
| ABSTRACT | Enclosed structures, such as guard towers, are provided which are designed to be easily transportable, constructed easily onsite and erected in a manner which produces an exceptionally blast resistant structure that is also advantageously designed for positioning within a perimeter wall. In particular, in some embodiments, the guard towers have a pentagon shape and are comprised of a plurality of composite panels. Each panel is able to be constructed onsite. The panels typically have a rectangular shape with at least one half of the panel constructed as a solid composite of concrete and metal. Once the panels are constructed, the panels are erected and arranged in a pentagon shape. The panels are bolted together with the use of vertical face connections. These connections provide better structural integrity, retained over time, particularly after subjection to a blast. In addition, the pentagon shape provides improved safety when positioned along a perimeter wall. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742813 |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/34321 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 12/08 (20130101) E04H 12/12 (20130101) E04H 12/18 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215471 | Lipson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michal Lipson (New York, New York); Xingchen Ji (New York, New York); Alexander Klenner (New York, New York); Xinwen Yao (Baltimore, Maryland); Yu Gan (Harriston, New Jersey); Alexander L. Gaeta (New York, New York); Christine P Hendon (Bronx, New York) |
| ABSTRACT | A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/100401 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/7257 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215472 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois); The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kuan He (Evanston, Illinois); Oliver Strider Cossairt (Evanston, Illinois); Aggelos K. Katsaggelos (Chicago, Illinois); Norbert Scherer (Chicago, Illinois); Mark Hereld (Chicago, Illinois) |
| ABSTRACT | A system to generate image representations includes a first objective that receives a first light beam emitted from a sample and a second objective that receives a second light beam emitted from the sample, where the first light beam and the second light beam have conjugate phase. The system also includes a first diffractive element to receive the first light beam and separate it into a first plurality of diffractive light beams that are spatially distinct, and a second diffractive element to receive the second light beam and separate it into a second plurality of diffractive light beams that are spatially distinct. The system further includes a detector that receives the first and second plurality of diffractive light beams. The first plurality of diffractive light beams and the second plurality of diffractive light beams are simultaneously directed and focused onto different portions of an image plane of the detector. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 15/734172 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) Original (OR) Class G01B 9/02041 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) Optical Elements, Systems, or Apparatus G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215554 | Araromi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Follows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Follows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Oluwaseun A. Araromi (Cambridge, Massachusetts); Conor J. Walsh (Cambridge, Massachusetts); Robert J. Wood (Cambridge, Massachusetts) |
| ABSTRACT | A strain sensor comprising a conductive member having a plurality of elements arranged adjacent to one another, and a non-conductive and elastically deformable material encapsulating the conductive member, wherein, in an equilibrium state, compressive forces cause at least one of the plurality of elements to contact at least a portion of an adjacent element, and wherein, when a strain is applied, a resulting elastic deformation causes at least one of the plurality of elements to space apart from an adjacent element such that the contacted portion decreases or is eliminated. A multi-axis force sensor comprising a sensing array comprising at least two planar sensors arranged radially on a planar substrate in antagonistic pairs, and a compressible member positioned between the substrate and a central portion of the sensing array, the compressible member acting to displace the central portion of the sensing array away from the substrate. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 17/056357 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2287 (20130101) Original (OR) Class G01L 5/1627 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215642 | Fincke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Randall Fincke (Lincoln, Massachusetts); Brian W. Anthony (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are provided for imaging of soft and hard tissues with ultrasound. Such systems and methods can provide for non-contact and quantitative ultrasound images of bone and soft tissue. A method for imaging a biological body segment of soft and hard tissues includes setting geometry and material properties according to a model of the biological body segment to thereby generate a simulated time series data set. The method further includes collecting reflective and transmissive time series data of the biological body segment to thereby form an experimental time series data set and minimizing a difference between the simulated time series data set and the experimental time series data set, thereby imaging the biological body segment. Regularizing travel-time and/or using full waveform tomographic techniques with level set methods enable recovery of cortical bone geometry. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/255410 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0672 (20130101) Original (OR) Class G01N 29/2418 (20130101) G01N 33/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215737 | MCLEOD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | ALEXANDER SWINTON MCLEOD (New York, New York); LIN XIONG (Bronx, New York); SHUAI ZHANG (New York, New York); DIMITRI N. BASOV (New York, New York) |
| ABSTRACT | An exemplary apparatus can provide radiation to a sample(s), which can include, for example, a radiation source arrangement configured to provide radiation, a beam splitter configured to split the radiation into (i) a first radiation, and (ii) a second radiation. An optical element can also be provided which, in operation, can, e.g., (a) receive the first radiation and the second radiation, (b) reflect the first radiation as a reference radiation, (c) provide the second radiation as illumination for the sample(s), (d) receive a resultant radiation from the sample(s) that can be based on the illumination from the second radiation, and (e) provide the reference radiation and the resultant radiation to be detected and used for interferometric imaging or spectroscopy. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149236 |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 20/02 (20130101) Original (OR) Class G01Q 30/18 (20130101) G01Q 60/24 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215758 | Jackson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Dennis H Jackson (Riverside, California) |
| ABSTRACT | The present invention relates to a system and method for calculating measurement uncertainty and determining measurement decision risk. Measurement uncertainty is calculated based on a plurality of error contributors. Measurement decision risk is evaluated using the measurement uncertainty, and mitigation strategies are applied to lower the probability of false acceptance and the probability of false rejection. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/145985 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31718 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216500 | YIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Heng YIN (Riverside, California); Xunchao HU (Riverside, California); Sheng YU (Riverside, California); Yu ZHENG (Riverside, California) |
| ABSTRACT | A novel high-throughput embedding generation and comparison system for executable code is presented in this invention. More specifically, the invention relates to a deep-neural-network based graph embedding generation and comparison system. A novel bi-directional code graph embedding generation has been proposed to enrich the information extracted from code graph. Furthermore, by deploying matrix manipulation, the throughput of the system has significantly increased for embedding generation. Potential applications such as executable file similarity calculation, vulnerability search are also presented in this invention. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198312 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/148 (20190101) Original (OR) Class G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6215 (20130101) G06K 9/6247 (20130101) G06K 9/6296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217149 | Fleizach |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Knowles Fleizach (San Diego, California) |
| ABSTRACT | Method and system for improved contrast enhancement. The method includes receiving, from at least one imaging system, first and second component chiral images, the first component chiral image being captured by a first filter that is polarized in a first direction, the second component chiral image being captured by a second filter that is polarized in a second direction, the second direction being substantially orthogonal to the first direction. The method also includes pre-enhancing, by a processor, one or both of said first component chiral image and said second component chiral image. Then the processor weights and sums at least a portion of the first and second component chiral images. Weighting and summing may be repeated until an optimal weight is reached. A contrast enhanced image may be generated after the optimal weight is reached. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738871 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/007 (20130101) Original (OR) Class G06T 5/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217185 | MUHLEMAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DANIEL H. MUHLEMAN (EL CAJON, California) |
| ABSTRACT | Method comprises receiving, by at least one memory, from at least one imaging system, at least two input images. The method includes comparing, by a processor, the at least two input images to each other such that nonstationary portions of the at least two input images are determined by either separating, by the at least one processor, each of the two input images into multiple pixel regions, and generating an error matrix for each of said multiple pixel regions. If an error value in the error matrix falls within a predetermined range, the pixel region is a nonstationary portion of the input images; or identifying, by a machine learning system, nonstationary portions of the input images. The pixels from nonstationary portions are removed from the at least two input images. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739351 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/32 (20170101) Original (OR) Class G06T 7/97 (20170101) G06T 2207/10032 (20130101) G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217402 | Wynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles Wynn (Groton, Massachusetts); Yaron Rachlin (Newton, Massachusetts); Ryan Sullenberger (Somerville, Massachusetts); Sumanth KAUSHIK (Belmont, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Wynn (Groton, Massachusetts); Yaron Rachlin (Newton, Massachusetts); Ryan Sullenberger (Somerville, Massachusetts); Sumanth KAUSHIK (Belmont, Massachusetts) |
| ABSTRACT | The ability to communicate with a specific subject at a prescribed location who lacks any communications equipment opens up many intriguing possibilities. Communications across noisy rooms, hail and warn applications, and localized communications directed at only the intended recipient are a few possibilities. We disclose and show localized acoustic communications, which we call photoacoustic communications, with a listener at long standoff distances using a modulated laser transmitted toward the receiver\'s ear. The optically encoded information is converted into acoustic messages via the photoacoustic effect. The photoacoustic conversion of the optical information into an audible signal occurs via the absorption of the light by ambient water vapor in the near area of the receiver\'s ear followed by airborne acoustic transmission to the ear. The recipient requires no external communications equipment to receive audible messages. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736212 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 2021/1704 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 15/046 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217474 | Whitesides et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Whitesides (Newton, Massachusetts); Brian J. Cafferty (Cambridge, Massachusetts); Alexei S. Ten (Evanston, Illinois); Michael J. Fink (Cambridge, Massachusetts); Daniel J. Preston (Cambridge, Massachusetts); Milan M. Mrksich (Hinsdale, Illinois); Amit A. Nagarkar (Cambridge, Massachusetts) |
| ABSTRACT | A machine-readable medium and methods of reading and writing same are disclosed. The machine-readable medium comprises a substrate having an array of addressable locations thereon, each addressable location adapted to be physically associated with a collection of non-polymeric molecules. The molecules in each collection are selected from a set of unambiguously identifiable molecules, each molecule uniquely associated with a predetermined position in a numerical value, wherein the presence of the molecule in the collection indicates a predetermined digit at the associated position and the absence of said molecule in the collection indicates a zero at said associated position. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214664 |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/008 (20130101) B82B 3/009 (20130101) B82B 3/0019 (20130101) B82B 3/0047 (20130101) Static Stores G11C 13/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217598 | VRIJSEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Geert VRIJSEN (Durham, North Carolina); Jungsang KIM (Chapel Hill, North Carolina); Robert SPIVEY (Durham, North Carolina); Ismail INLEK (Durham, North Carolina); Yuhi AIKYO (Durham, North Carolina) |
| ABSTRACT | Systems and methods for loading microfabricated ion traps are disclosed. Photo-ablation via an ablation pulse is used to generate a flow of atoms from a source material, where the flow is predominantly populated with neutral atoms. As the neutral atoms flow toward the ion trap, two-photon photo-ionization is used to selectively ionize a specific isotope contained in the atom flow. The velocity of the liberated atoms, atom-generation rate, and/or heat load of the source material is controlled by controlling the fluence of the ablation pulse to provide high ion-trapping probability while simultaneously mitigating generation of heat in the ion-trapping system that can preclude cryogenic operation. In some embodiments, the source material is held within an ablation oven comprising an electrically conductive housing that is configured to restrict the flow of agglomerated neutral atoms generated during photo-ablation toward the ion trap. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950703 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Electric Discharge Tubes or Discharge Lamps H01J 49/0018 (20130101) Original (OR) Class H01J 49/161 (20130101) H01J 49/422 (20130101) H01J 49/0463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217617 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua A. Robinson (Spring Mills, Pennsylvania); Natalie Briggs (Benton City, Washington) |
| ABSTRACT | This disclosure relates to methods of growing crystalline layers on amorphous substrates by way of an ultra-thin seed layer, methods for preparing the seed layer, and compositions comprising both. In an aspect of the invention, the crystalline layers can be thin films. In a preferred embodiment, these thin films can be free-standing. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/301117 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02568 (20130101) Original (OR) Class H01L 21/02631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217952 | Jarillo-Herrero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong MA (Cambridge, Massachusetts); Nuh GEDIK (Watertown, Massachusetts); Suyang XU (Cambridge, Massachusetts); Zhiren ZHENG (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong MA (Cambridge, Massachusetts); Nuh GEDIK (Watertown, Massachusetts); Suyang XU (Cambridge, Massachusetts); Zhiren ZHENG (Cambridge, Massachusetts) |
| ABSTRACT | An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094141 |
| CURRENT CPC | Static Stores G11C 13/0069 (20130101) G11C 2213/35 (20130101) G11C 2213/53 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/10 (20130101) Original (OR) Class H01L 45/142 (20130101) H01L 45/143 (20130101) H01L 45/148 (20130101) H01L 45/149 (20130101) H01L 45/1206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218153 | Chapman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam J. Chapman (Medford, Massachusetts); Alan J. Fenn (Wayland, Massachusetts); Pierre Dufilie (Marlborough, Massachusetts) |
| ABSTRACT | A compact shallow cavity-backed discone antenna array for conformal omnidirectional antenna applications is disclosed. The antenna array comprises a plurality of discone antennas arranged in a ring array within a circular contoured conical cavity. The cavity is covered with an electrically transparent radome. The individual discone antenna elements are fed with coaxial transmission lines. Good performance is demonstrated by simulation and by experiment in terms of reflection coefficient and omnidirectional gain radiation patterns from about 960 MHz to 1220 MHz. In one embodiment, the shallow cavity-backed discone antenna array may be used as a flush-mounted antenna that conforms to the outer mold line of an aircraft. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 16/850372 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/286 (20130101) H01Q 1/421 (20130101) H01Q 13/18 (20130101) H01Q 21/0056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218350 | WEST et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James WEST (Baltimore, Maryland); Ugur ERTURUN (Baltimore, Maryland); Sung Hoon KANG (Lutherville-Timonium, Maryland); Adebayo EISAPE (Baltimore, Maryland) |
| ABSTRACT | Disclosed are device implementations for a hybrid energy harvesting device and methods for harvesting mechanical energy from the ambient. The various device implementations utilize a combination of electrostatic energy conversion and piezoelectric energy conversion elements. The method simultaneously converts mechanical energy into electrical charge by electrostatic and piezoelectric energy harvesting. The devices include a piezoelectric harvester including a pair of electrodes and piezoelectric nanocomposite polymer, an electrostatic harvester including an electret film and a pair of electrostatic electrodes. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 17/059735 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/113 (20130101) H01L 41/183 (20130101) H01L 41/0472 (20130101) Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) H02N 2/181 (20130101) H02N 2/186 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218382 | Hickle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Mark D. Hickle (Merrimack, New Hampshire) |
| ABSTRACT | Techniques are disclosed for filtering a radio frequency (RF) signal using an N-path bandstop filter with an extended, spurious-free upper passband. In an embodiment, a bandstop filter includes a bank of three switched capacitors in series with the RF signal path through the filter, in contrast to 4- or 8-capacitor banks or other bandstop filters where N is a power of 2. In this 3-path example configuration, an undesirable spurious bandstop notch at the 3rd and 5th harmonics of the clock frequency are eliminated or substantially reduced, improving performance of the filter in the desired passbands while preserving the notch in the desired stopband at high RF signal frequencies. Another N-path bandstop filter embodiment includes a bridged T-coil circuit, which absorbs a shunt capacitance of the bandstop filter into the bridged T-coil circuit. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738441 |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/004 (20130101) H03H 7/0153 (20130101) Original (OR) Class H03H 11/0466 (20130101) H03H 2007/013 (20130101) H03H 2011/0488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218408 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian Daffern Hong (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Daffern Hong (Sierra Madre, California); Seyed Ali Hajimiri (Pasadena, California) |
| ABSTRACT | The present disclosure includes a frequency divider circuit that includes a superharmonically injection-locked ring oscillator, injection circuitry, and various switches. The input can include a collection of signal components at different phases that are all at the same, but changeable, frequency. The divider\'s division ratio can be changed during the divider\'s operation by, for example, utilizing one or more switches to change: the number of stages in the ring oscillator, and/or which stage(s) of the ring oscillator are injected into by which input signal components. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/145886 |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1228 (20130101) Pulse Technique H03K 3/0322 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/24 (20130101) Original (OR) Class H03L 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20210212657 | GAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cardiac Motion, LLC (Truckee, California); The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaomeng GAO (Dublin, California); Xiaonan JIANG (Davis, California); Xiaoguang LIU (Davis, California); Dennis MATTHEWS (Meadow Vista, California); Saul SCHAEFER (Davis, California) |
| ABSTRACT | The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject\'s home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor\'s office, or hospital. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/102838 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/02 (20130101) A61B 8/04 (20130101) Original (OR) Class A61B 8/08 (20130101) A61B 8/488 (20130101) A61B 8/5207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213041 | Ting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Miguel N. Rivera (Belmont, Massachusetts); Vikram Deshpande (Belmont, Massachusetts); Kshitij Arora (North Quincy, Massachusetts); Benjamin Dylan Greenbaum (New York, New York); Alexander V. Solovyov (New York, New York) |
| ABSTRACT | Methods for predicting response to immunotherapy and selecting immunotherapy for treating cancer, e.g., cancer of epithelial origin, in a subject. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/967497 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213168 | BONASSAR et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence J. BONASSAR (Ithaca, New York); Roger HARTL (New York, New York); Robert D. BOWLES (Ithaca, New York); Harry H. GEBHARD (Tuebingen, Germany) |
| ABSTRACT | The present invention relates to a tissue-engineered intervertebral disc (IVD) suitable for total disc replacement in a mammal and methods of fabrication. The IVD comprises a nucleus pulposus structure comprising a first population of living cells that secrete a hydrophilic protein and an annulus fibrosis structure surrounding and in contact with the nucleus pulposus structure, the annulus fibrosis structure comprising a second population of living cells and type I collagen. The collagen fibrils in the annulus fibrosis structure are circumferentially aligned around the nucleus pulposus region due to cell-mediated contraction in the annulus fibrosis structure. Also disclosed are methods of fabricating tissue-engineered intervertebral discs. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/105154 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/442 (20130101) A61F 2002/444 (20130101) A61F 2002/445 (20130101) A61F 2002/4435 (20130101) A61F 2002/4445 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/22 (20130101) A61L 27/24 (20130101) A61L 27/44 (20130101) A61L 27/52 (20130101) A61L 27/3658 (20130101) Original (OR) Class A61L 27/3691 (20130101) A61L 27/3817 (20130101) A61L 27/3856 (20130101) A61L 27/3886 (20130101) A61L 2430/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213264 | LIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (COLLEGE PARK, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SANWEI LIU (SAN JOSE, California); SANGWOOK CHU (SAN JOSE, California); REZA GHODSSI (POTOMAC, Maryland); LUKE BEARDSLEE (ATLANTA, Georgia); ASHLEY AUGUSTINY CHAPIN (WASHINGTON, District of Columbia) |
| ABSTRACT | A microneedle system includes an ingestible structure and one or more microneedle units secured to a surface of the structure. Each microneedle unit has a plurality of barb members extending from the outer surface of a microneedle. The microneedle unit is secured to the structure by a displacement member, which displaces the microneedle unit when in a released state. The displacement member may be held in a compressed state by a dissolvable coating. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149277 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0053 (20130101) A61M 2205/0238 (20130101) A61M 2210/1042 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) B29C 64/135 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7546 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213297 | Yan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dayun Yan (Ashburn, Virginia); Michael Keidar (Baltimore, Maryland); Eda GJIKA (Washington, District of Columbia) |
| ABSTRACT | A method and system of adaptive cold atmospheric based treatment for diseased tissues, such as an area with cancerous cells, is disclosed. A gas such as helium is ionized via supplying power between and anode and a cathode to create an initial cold atmospheric plasma jet. The initial plasma jet is directed toward the area for a sufficient time, such as 10 seconds, to sensitize the cells via a reactive species. A reactive treatment, such as H2O2 or TMZ, is directed to the sensitized cells. The effectiveness of the reactive treatment is increased by the process of sensitizing the cells. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 15/734149 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4188 (20130101) A61K 33/40 (20130101) A61K 41/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/44 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/32366 (20130101) H01J 37/32449 (20130101) H01J 37/32825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213329 | Wechsler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emily Wechsler (Dallas, Texas); Ryan Halter (Lyme, New Hampshire); John A. Batsis (Hanover, New Hampshire) |
| ABSTRACT | Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170). |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/055412 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00043 (20130101) A63B 21/0552 (20130101) A63B 21/4035 (20151001) A63B 24/0062 (20130101) Original (OR) Class A63B 2220/17 (20130101) A63B 2220/51 (20130101) A63B 2220/62 (20130101) A63B 2220/833 (20130101) A63B 2225/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213419 | Anyanwu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John-Timothy Anyanwu (Ann Arbor, Michigan); Yiren Wang (Ann Arbor, Michigan); Ralph T. Yang (Ann Arbor, Michigan) |
| ABSTRACT | A method of grafting a silica support includes adding the silica support to a solvent, resulting in a first solution, adding an amount of silane to the first solution, resulting in a second solution, filtering grafted silica support from the second solution, and drying the grafted silica support. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150376 |
| CURRENT CPC | Separation B01D 53/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/283 (20130101) Original (OR) Class B01J 20/3259 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213424 | Sofranko et al. |
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| FUNDED BY |
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| APPLICANT(S) | John A. Sofranko (Weston, Massachusetts); Fanxing Li (Raleigh, North Carolina); Luke Michael Neal (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina); Seif Yusuf (Raleigh, North Carolina); Ryan Dudek (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. Sofranko (Weston, Massachusetts); Fanxing Li (Raleigh, North Carolina); Luke Michael Neal (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina); Seif Yusuf (Raleigh, North Carolina); Ryan Dudek (Raleigh, North Carolina) |
| ABSTRACT | Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/115115 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/14 (20130101) B01J 23/002 (20130101) Original (OR) Class B01J 23/02 (20130101) B01J 23/005 (20130101) B01J 23/30 (20130101) B01J 35/002 (20130101) B01J 35/0006 (20130101) B01J 35/10 (20130101) B01J 37/06 (20130101) B01J 37/0081 (20130101) B01J 37/088 (20130101) B01J 37/0215 (20130101) Acyclic or Carbocyclic Compounds C07C 4/06 (20130101) C07C 5/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213523 | Peterson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | G. P. "Bud" Peterson (Atlanta, Georgia); Haiping Hong (Rapid City, South Dakota) |
| ABSTRACT | Disclosed herein is a method of homogeneously mixing solids, comprising: mixing, in a fluid medium, at least a first Got nanoparticle material and a surfactant, wherein the surfactant causes the first nanoparticle material to distribute uniformly in the fluid medium and have a specific charge; adding, to the fluid medium, a second nanoparticle material, wherein the surfactant has a charge of opposite polarity to the zeta potential of the second nanoparticle material; attaching the second nanoparticle material to the first Nnanoparticle material using the charge attraction of the surfactant and the second nanoparticle material to obtain a homogeneous material; and removing the attached first and second nanoparticle materials from the fluid medium to obtain a solid homogeneous material. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054202 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) Original (OR) Class B22F 1/0074 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214079 | Chilson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Phillip B. Chilson (Norman, Oklahoma); Antonio R. Segales Espinosa (Norman, Oklahoma); William J. Doyle (Norman, Oklahoma); Tyler M. Bell (Norman, Oklahoma); Brian R. Greene (Norman, Oklahoma); Joshua J. Martin (Norman, Oklahoma); Elizabeth A. Pillar-Little (Norman, Oklahoma); Gustavo Britto Hupsel de Azevedo (Norman, Oklahoma) |
| ABSTRACT | An unmanned aerial system (UAS) adapted to measure one or more atmospheric conditions has a frame and a plurality of motorized rotors suspended on arms extending outward from the frame. The UAS further includes a flight control module that includes a computer programmable flight control board and a sensor package that has an air sampling scoop, a first sensor positioned inside the air sampling scoop, and a ducted fan inside the air sampling scoop. The ducted fan is configured to draw air through the air sampling scoop in contact with the first sensor. The ducted fan can be configured to operate only when the UAS is above a predetermined altitude. The UAS may also be configured to operate in a “wind vane” mode in which wind speed and direction is determined based on the pitch and heading of the UAS. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146352 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/027 (20130101) B64C 2201/108 (20130101) B64C 2201/125 (20130101) B64C 2201/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214282 | Temme et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (Berkeley, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria\'s nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/148173 |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214325 | Bond et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jesse Quentin Bond (Syracuse, New York); Ran Zhu (Boston, Massachusetts) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (SYRACUSE, New York) |
| INVENTOR(S) | Jesse Quentin Bond (Syracuse, New York); Ran Zhu (Boston, Massachusetts) |
| ABSTRACT | A process for forming protoanemonin from an amount of levulinic acid or an amount of α-Angelica lactone using oxidative dehydrogenation. Biomass-derived levulinic acid (LA) is a green platform chemical and, using an oxidative scission pathway can be transformed into cyclic intermediates, namely angelicalactones to form protoanemonin. The oxidative dehydrogenation may be heterogeneously catalyzed in a gas-phase to perform aerobic oxidation using a solid oxide such as vanadium oxide. Protoanemonin is an intriguing polyfunctional molecule that is uniquely suited to bio-based production, and can be synthesized in yields from 50%-75% during periods of transient reactor operation. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/148615 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/22 (20130101) Heterocyclic Compounds C07D 307/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214397 | LY et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Danith H. LY (Pittsburgh, Pennsylvania); Srinivas RAPIREDDY (Pittsburgh, Pennsylvania); Bichismita SAHU (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers. |
| FILED | Wednesday, August 26, 2020 |
| APPL NO | 17/003131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 229/12 (20130101) C07C 271/20 (20130101) Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Peptides C07K 1/04 (20130101) C07K 1/08 (20130101) C07K 14/003 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214507 | Sumerlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brent S. Sumerlin (Gainesville, Florida); William L.A. Brooks (Jacksonville, Florida); Christopher Deng (Goleta, California) |
| ABSTRACT | Boronic acid monomers, methods of making boronic acid monomer, and the like, are provided. Embodiments of the present disclosure are advantageous in that the boronic acid monomers are water soluble at a neutral pH, which is uncommon for boronic acids. As a result, the boronic acid monomers can be used in aqueous polymerization reactions with other hydrophilic monomers to yield polymers including boronic acids and esters. |
| FILED | Wednesday, March 24, 2021 |
| APPL NO | 17/211255 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/08 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 85/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214508 | Rawashdeh-Omary et al. |
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| FUNDED BY |
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| APPLICANT(S) | Texas Woman\'s University (Denton, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manal A. Rawashdeh-Omary (Denton, Texas); Ruaa M. Almotawa (Denton, Texas); Mohammad A. Omary (Denton, Texas) |
| ABSTRACT | The embodiments described herein pertains to a new design method to produce copper, silver or gold based metal functional coordination polymers with excellent potential towards optoelectronic devices, gas storage and separation, optical sensors, and other applications. |
| FILED | Tuesday, July 09, 2019 |
| APPL NO | 17/058764 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) C07F 1/10 (20130101) C07F 1/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214611 | Bawendi et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi Bawendi (Cambridge, Massachusetts); Daniel Franke (Cambridge, Massachusetts); Matthias Ginterseder (Cambridge, Massachusetts) |
| ABSTRACT | A semiconductor nanocrystal can be made by an in situ redox reaction between an M donor and an E donor. |
| FILED | Tuesday, January 12, 2021 |
| APPL NO | 17/147057 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/0883 (20130101) C09K 11/883 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214613 | Jákli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kent State University (Kent, Ohio); The University of Akron (Akron, Ohio) |
| ASSIGNEE(S) | Kent State University (Kent, Ohio); The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Antal Jákli (Kent, Ohio); Chenrun Feng (Kent, Ohio); Chathuranga Prageeth Hemantha Rajapaksha (Kent, Ohio); Vikash Kaphle (Kent, Ohio); Thein Kyu (Akron, Ohio) |
| ABSTRACT | An ionic liquid crystal elastomer composition includes a liquid crystal elastomer; and an ionic liquid. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/248127 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/12 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/14 (20130101) C08F 2/50 (20130101) C08F 20/30 (20130101) C08F 22/20 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/07 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/02 (20130101) Original (OR) Class C09K 19/542 (20130101) C09K 2019/0448 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214713 | Bashor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Caleb J. Bashor (Boston, Massachusetts); Jason Hung-Ying Yang (Watertown, Massachusetts); Arnaud Gutierrez (Somerville, Massachusetts); Wooseok Steven Ahn (Tenafly, New Jersey); James J. Collins (Newton, New Jersey); Brandon Gei-Chin Wong (Brighton, Massachusetts); Ahmad S. Khalil (Lexington, Massachusetts) |
| ABSTRACT | Disclosed herein are a high-throughput continuous culture system and novel methodologies for the experimental evolution of natural and synthetic microbes using the continuous culture system. The microbial culture is exposed to a stress ramp function which is overlaid on top of a culture fitness function. The amount of stress applied to the culture is increased in response to increased fitness of the microbial culture. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 16/081975 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/01 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214857 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Haiyan Wang (West Lafayette, Indiana); Xuejing Wang (West Lafayette, Indiana); Xinghang Zhang (West Lafayette, Indiana) |
| ABSTRACT | A method of the fabricating a metal-nitride vertically aligned nanocomposites is disclosed which includes applying a pulsed laser onto a composite target, the composite target including a two-phase metal-nitride plasmonic nanostructure, depositing adatoms of the composite target onto a substrate, and nucleating metal over the substrate and growing metal and nitride thereover until a predetermined size of vertically aligned metal nitride nanocomposite is achieved including metal nanorods embedded in nitride. |
| FILED | Saturday, December 26, 2020 |
| APPL NO | 17/134340 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/025 (20130101) C30B 23/066 (20130101) C30B 29/02 (20130101) C30B 29/38 (20130101) C30B 29/605 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215471 | Lipson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michal Lipson (New York, New York); Xingchen Ji (New York, New York); Alexander Klenner (New York, New York); Xinwen Yao (Baltimore, Maryland); Yu Gan (Harriston, New Jersey); Alexander L. Gaeta (New York, New York); Christine P Hendon (Bronx, New York) |
| ABSTRACT | A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source. |
| FILED | Friday, August 10, 2018 |
| APPL NO | 16/100401 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/7257 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215472 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois); The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kuan He (Evanston, Illinois); Oliver Strider Cossairt (Evanston, Illinois); Aggelos K. Katsaggelos (Chicago, Illinois); Norbert Scherer (Chicago, Illinois); Mark Hereld (Chicago, Illinois) |
| ABSTRACT | A system to generate image representations includes a first objective that receives a first light beam emitted from a sample and a second objective that receives a second light beam emitted from the sample, where the first light beam and the second light beam have conjugate phase. The system also includes a first diffractive element to receive the first light beam and separate it into a first plurality of diffractive light beams that are spatially distinct, and a second diffractive element to receive the second light beam and separate it into a second plurality of diffractive light beams that are spatially distinct. The system further includes a detector that receives the first and second plurality of diffractive light beams. The first plurality of diffractive light beams and the second plurality of diffractive light beams are simultaneously directed and focused onto different portions of an image plane of the detector. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 15/734172 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) Original (OR) Class G01B 9/02041 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) Optical Elements, Systems, or Apparatus G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215508 | Watson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | College of William and Mary (Williamsburg, Virginia) |
| ASSIGNEE(S) | College of William and Mary (Williamsburg, Virginia) |
| INVENTOR(S) | Amanda Watson (Williamsburg, Virginia); Andrew Lyubovsky (Williamsburg, Virginia); Gang Zhou (Williamsburg, Virginia) |
| ABSTRACT | A method is provided for monitoring relative positions of two objects sharing a common joint during motion between the two objects. An electromagnet is positioned on a first object and a magnetic sensor is positioned on a second object. The electromagnet\'s power or polarity is cycled during a monitoring session in accordance with a periodic schedule of alternating power-on/power-off periods or alternating-polarity periods, respectively. The magnetic sensor\'s output during one or more of the power-off periods or the alternating-polarity periods is used to remove environmental magnetic interference to dynamically determine the distance between the electromagnet and the magnetic sensor where the determined distance and the north pole orientation of the electromagnet are indicative of relative positions of the first object and the second object. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743502 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1126 (20130101) A61B 2562/0223 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/30 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215636 | Claussen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); Kshama Parate (Ames, Iowa); Mark C. Hersam (Willmette, Illinois); Sonal V. Rangnekar (Chicago, Illinois) |
| ABSTRACT | Methods and systems of fabrication of high resolution, high-throughput electrochemical sensing circuits on a substrate. High resolution electrochemical sensing circuits are printed by an effective additive technique to the substrate. Optionally, post-print annealing converts electrochemically inactive printed graphene into one that is electrochemically active. The printing can be by aerosol jet printing, but is not necessarily limited thereto. An example is inkjet printing and then the post-print annealing. Ink formulation would be adjusted for effectiveness with inkjet printing. Optionally biorecognition agents can be covalently bonded to the printed graphene for the purpose of electrochemical biosensing. High throughput fabrication of high-resolution graphene circuits (feature sizes in the tens of microns <50 μm) for electrochemical biosensing is possible by chemical functionalization of the graphene surface with a biological agent. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/248211 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/08 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 80/00 (20141201) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) B41M 5/0023 (20130101) B41M 7/009 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4148 (20130101) Original (OR) Class G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215679 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Sogang University (Seoul, South Korea) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ki-Bum Lee (Piscataway, New Jersey); Jin-Ho Lee (Piscataway, New Jersey); Jeong-Woo Choi (Seoul, South Korea); Jin-Ha Choi (Seoul, South Korea) |
| ABSTRACT | Nanorod devices for isolating and characterizing target cellular components are provided. Methods of isolating, detecting, and/or characterizing the components are also provided. Methods of use and treatment are further disclosed, such as treating diseases identified using the nanorods and/or using differentiated stem cells identified using the provided nanorods. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142950 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/533 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/40 (20130101) H01F 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215769 | Chow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mo-Yuen Chow (Raleigh, North Carolina); Habiballah Rahimi Eichi (Raleigh, North Carolina); Cong Sheng Huang (Raleigh, North Carolina); Bharat Balagopal (Raleigh, North Carolina) |
| ABSTRACT | Battery parameters, state of charge, and state of health co-estimation are disclosed. According to an aspect, a method includes determining a terminal current and a terminal voltage of a battery. The method also includes maintaining a battery model that defines a relationship between a parameter of the battery, the terminal current, and the terminal voltage. Further, the method includes determining the parameter of the battery based on the battery model and the acquired terminal current and the terminal voltage. Temperature effects can also be accounted for by the co-estimation. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/740366 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) G01R 31/3835 (20190101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 10/425 (20130101) H01M 10/0525 (20130101) H01M 2010/4271 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216020 | Magnusson et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Magnusson (Arlington, Texas); Kyu Lee (Euless, Texas); Hafez Hemmati (Arlington, Texas); Pawarat Bootpakdeetam (Arlington, Texas) |
| ABSTRACT | A method of fabricating a metasurface comprises coating a photoresist film onto a substrate and loading the coated substrate into a laser interference lithography setup, exposing the photoresist film via a laser with a first interference pattern, the first interference pattern having a first period and a first exposure energy, subsequently exposing the coated substrate with a second interference pattern, the second interference pattern having a second period and a second exposure energy, developing the exposed portions of the photoresist film to form a periodic pattern in the photoresist, and transferring the periodic pattern into the substrate, the substrate supporting an appropriate film system that embodies the final metasurface device. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150171 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0035 (20130101) G03F 7/094 (20130101) G03F 7/162 (20130101) G03F 7/70408 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216500 | YIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Heng YIN (Riverside, California); Xunchao HU (Riverside, California); Sheng YU (Riverside, California); Yu ZHENG (Riverside, California) |
| ABSTRACT | A novel high-throughput embedding generation and comparison system for executable code is presented in this invention. More specifically, the invention relates to a deep-neural-network based graph embedding generation and comparison system. A novel bi-directional code graph embedding generation has been proposed to enrich the information extracted from code graph. Furthermore, by deploying matrix manipulation, the throughput of the system has significantly increased for embedding generation. Potential applications such as executable file similarity calculation, vulnerability search are also presented in this invention. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198312 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/148 (20190101) Original (OR) Class G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6215 (20130101) G06K 9/6247 (20130101) G06K 9/6296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217490 | MISHRA et al. |
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| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (, None) |
| INVENTOR(S) | Bhubaneswar MISHRA (Great Neck, New York); Giuseppe NARZISI (New York, New York) |
| ABSTRACT | Exemplary methods, procedures, computer-accessible medium, and systems for base-calling, aligning and polymorphism detection and analysis using raw output from a sequencing platform can be provided. A set of raw outputs can be used to detect polymorphisms in an individual by obtaining a plurality of sequence read data from one or more technologies (e.g., using sequencing-by-synthesis, sequencing-by-ligation, sequencing-by-hybridization, Sanger sequencing, etc.). For example, provided herein are exemplary methods, procedures, computer-accessible medium and systems, which can include and/or be configured for obtaining raw output from a sequencing platform configured to be used for reading fragment(s) of genomes, obtaining reference sequences for the genomes obtained independently from the raw output, and generating a base-call interpretation and/or alignment using the raw output and the reference sequences. For example, a score function can be determined based on information associated with the sequencing platform that can be used to analyze polymorphisms based on the base-call interpretation and/or alignment. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/216000 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217606 | JARROLD et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin F. JARROLD (Bloomington, Indiana); Daniel BOTAMANENKO (Bloomington, Indiana) |
| ABSTRACT | An electrostatic linear ion trap (ELIT) array includes multiple elongated charge detection cylinders arranged end-to-end and each defining an axial passageway extending centrally therethrough, a plurality of ion mirror structures each defining a pair of axially aligned cavities and an axial passageway extending centrally therethrough, wherein a different ion mirror structure is disposed between opposing ends of each cylinder, and front and rear ion mirrors each defining at least one cavity and an axial passageway extending centrally therethrough, the front ion mirror positioned at one end of the arrangement of charge detection cylinders and the rear ion mirror positioned at an opposite end of the arrangement of charge detection cylinders, wherein the axial passageways of the charge detection cylinders, the ion mirror structures, the front ion mirror and the rear ion mirror are coaxial to define a longitudinal axis passing centrally through the ELIT array. In a second aspect, an ELIT array comprises a plurality of non-coaxial ELIT regions, wherein ions are selectively guided into each of the ELIT regions. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 17/058561 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/025 (20130101) H01J 49/0031 (20130101) H01J 49/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217617 | Robinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua A. Robinson (Spring Mills, Pennsylvania); Natalie Briggs (Benton City, Washington) |
| ABSTRACT | This disclosure relates to methods of growing crystalline layers on amorphous substrates by way of an ultra-thin seed layer, methods for preparing the seed layer, and compositions comprising both. In an aspect of the invention, the crystalline layers can be thin films. In a preferred embodiment, these thin films can be free-standing. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/301117 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02568 (20130101) Original (OR) Class H01L 21/02631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217974 | SCHMEDAKE et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Andrew SCHMEDAKE (Charlotte, North Carolina); Michael George WALTER (Charlotte, North Carolina); Yong ZHANG (Charlotte, North Carolina); Margaret KOCHERGA (Charlotte, North Carolina) |
| ABSTRACT | A variety of hexacoordinate pincer complexes are described herein having electronic structure advantageous for electronic and/or optoelectronic applications. In some embodiments, the pincer complexes are luminescent, exhibiting fluorescence and/or phosphorescence. Briefly, a hexacoordinate complex comprises a central atom selected from the group consisting of silicon, germanium, and tin, and two pincer ligands bound to the central atom, wherein the hexacoordinate complex is luminescent. In another aspect, a hexacoordinate complex comprises a central atom selected from the group consisting of silicon, germanium and tin, and two pincer ligands bound to the central atom, wherein the difference between the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) of the hexacoordinate complex is at least 1.5 eV. |
| FILED | Wednesday, May 29, 2019 |
| APPL NO | 17/057308 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/025 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0067 (20130101) H01L 51/0072 (20130101) H01L 51/0094 (20130101) Original (OR) Class H01L 51/5072 (20130101) H01L 2251/552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218028 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Laisuo Su (Pittsburgh, Pennsylvania); Baby Reeja-Jayan (Pittsburgh, Pennsylvania) |
| ABSTRACT | Manufacturing technology to fabricate liquid metal-based soft and flexible electronics (sensors, antennas, etc.) in a high-throughput fashion, with fabrication rates that may approach that of the traditional integrated circuit components and circuits, are described. The technique allows creation of liquid-metal-only circuits, as well as seamless integration of solid IC chips into the circuits, in which liquid metal traces are used as flexible interconnects and/or as other circuit elements. The process may be applied at the wafer scale and may be integrated into the traditional microelectronics fabrication processes. Many sensors, antennas, and other circuit elements may be directly created using liquid metal, and when combined with the IC chips, a broad range of electronic functionality may be provided in a flexible, soft circuit that can be conformable, wearable. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886948 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/583 (20130101) H01M 4/606 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218366 | Naing et al. |
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| FUNDED BY |
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| APPLICANT(S) | MUMEC, INC. (Oakland, California) |
| ASSIGNEE(S) | MUMEC, INC. (Oakland, California) |
| INVENTOR(S) | Thura Lin Naing (Union City, California); Tristan Orion Rocheleau (Berkeley, California) |
| ABSTRACT | The present disclosure provides a super-regenerative transceiver with a feedback element having a controllable gain. The super-regenerative transceiver utilizes the controllable gain to improve RF signal data sensitivity and improve RF signal data capture rates. Super-regenerative transceivers described herein permit signal data capture over a broad range of frequencies and for a range of communication protocols. Super-regenerative transceivers described herein are tunable, consume very little power for operation and maintenance, and permit long term operation even when powered by very small power sources (e.g., coin batteries). |
| FILED | Sunday, January 24, 2021 |
| APPL NO | 17/248411 |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/30 (20130101) H03B 5/32 (20130101) Original (OR) Class H03B 5/323 (20130101) H03B 5/1215 (20130101) Demodulation or Transference of Modulation From One Carrier to Another H03D 11/04 (20130101) H03D 11/08 (20130101) H03D 2200/0074 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/02 (20130101) H03H 9/02259 (20130101) H03H 9/02393 (20130101) H03H 9/2447 (20130101) H03H 9/2457 (20130101) Transmission H04B 1/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218392 | Carrigan |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph T. Carrigan (Columbia, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a system and method of physically modulating a digital signal across a medium. A signal is sent one bit at a time (serially) as a period of high voltage followed by a period of low voltage. The present invention includes several major advantages. One advantage is that the code to execute the method is very lightweight. Another advantage is that the signals require no synchronization source. The signals of the present invention function as their own synchronization. |
| FILED | Monday, February 20, 2017 |
| APPL NO | 15/999841 |
| CURRENT CPC | Pulse Technique H03K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218423 | Barton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taylor Wallis Barton (Boulder, Colorado); William Sear (Aurora, Colorado) |
| ABSTRACT | Systems and methods for controlling power amplifier (PA) performance metrics such as linearity and stability based on out-of-band feedback are presented. Various embodiments provide for synthesizing negative baseband termination using a feedback network between the drain and gate bias paths of the PA, so that the intermodulation distortion (IMD) is suppressed without an increase in system complexity. Other embodiments include a feedback network topology between the drain and gate bias paths of the PA that provides stability enhancement of the PA without the need for conventional stability networks in the radio frequency (RF) path. The out-of-band feedback nature of the approach means that the continuous wave (CW) RF performance is not perturbed, enabling conventional design techniques to be used for the input and output matching networks while enhancing aspects of the PA performance. |
| FILED | Tuesday, January 12, 2021 |
| APPL NO | 17/146965 |
| CURRENT CPC | Transmission H04B 1/0057 (20130101) Original (OR) Class H04B 1/0458 (20130101) H04B 1/0475 (20130101) H04B 1/1036 (20130101) H04B 2001/0433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218498 | Effros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michelle Effros (Pasadena, California); Yuxin Liu (Pasadena, California) |
| ABSTRACT | Systems and methods in accordance with various embodiments of the invention enable communicating using nested Low Density Parity Check (LDPC) codes. A nested LDPC code is an LDPC code having a full blocklength, where shorter blocklengths of the nested LDPC code can be utilized as shorter blocklength LDPC codes. In certain embodiments, a transmitter utilizes a nested LDPC code to communicate via a point-to-point connection. In several embodiments, multiple transmitters utilize nested LDPC codes to communicate simultaneously via a Random Access Channel. One embodiment includes a transmitter capable of encoding a message as symbols using a nested LDPC code until a feedback message indicating an end of epoch message is received. A receiver can determine whether a decoding rule is satisfied at predetermined decode times and transmit an end of epoch message when the decoder can decode a message based upon the nested LDPC code. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146343 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1105 (20130101) H03M 13/1148 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0041 (20130101) H04L 1/0057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218499 | Yavas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Recep Can Yavas (Pasadena, California); Victoria Kostina (Pasadena, California); Michelle Effros (Pasadena, California) |
| ABSTRACT | Communication systems and methods in accordance with various embodiments of the invention employ a rateless coding strategy in which an encoder utilizes codewords located within a restricted subset of a multi-dimensional sphere. In one embodiment, a transmitter is configured to encode message data as symbols using a rateless code until an end of epoch message is received, where the rateless code comprises a set of codewords characterized in that they are located within a restricted subset of a multi-dimensional sphere. A receiver receives observed symbols and at each of a predetermined set of decode times, determines whether a decoding rule is satisfied. When the decoding rule is satisfied, the receiver decodes at least one message using the rateless code and transmits an end of epoch message. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146462 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0643 (20130101) H04L 1/0687 (20130101) Original (OR) Class H04L 12/1868 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20210213424 | Sofranko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John A. Sofranko (Weston, Massachusetts); Fanxing Li (Raleigh, North Carolina); Luke Michael Neal (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina); Seif Yusuf (Raleigh, North Carolina); Ryan Dudek (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. Sofranko (Weston, Massachusetts); Fanxing Li (Raleigh, North Carolina); Luke Michael Neal (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina); Seif Yusuf (Raleigh, North Carolina); Ryan Dudek (Raleigh, North Carolina) |
| ABSTRACT | Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/115115 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/14 (20130101) B01J 23/002 (20130101) Original (OR) Class B01J 23/02 (20130101) B01J 23/005 (20130101) B01J 23/30 (20130101) B01J 35/002 (20130101) B01J 35/0006 (20130101) B01J 35/10 (20130101) B01J 37/06 (20130101) B01J 37/0081 (20130101) B01J 37/088 (20130101) B01J 37/0215 (20130101) Acyclic or Carbocyclic Compounds C07C 4/06 (20130101) C07C 5/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213501 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Keystone Tower Systems, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric D. SMITH (Boulder, Colorado); Rosalind K. TAKATA (Denver, Colorado); Alexander H. SLOCUM (Bow, New Hampshire); Samir A. NAYFEH (Shrewsbury, Massachusetts) |
| ABSTRACT | Feeding stock used to form a tapered structure into a curving device such that each point on the stock undergoes rotational motion about a peak location of the tapered structure; and the stock meets a predecessor portion of stock along one or more adjacent edges. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/199019 |
| CURRENT CPC | Rolling of Metal B21B 39/02 (20130101) Original (OR) Class Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 37/124 (20130101) B21C 37/126 (20130101) B21C 37/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213753 | Secor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ethan Benjamin Secor (Albuquerque, New Mexico) |
| ABSTRACT | Aerosol jet printing offers a versatile, high-resolution capability for flexible and hybrid electronics. By integrating a flow-through ink cartridge with an ink recirculation system, ink composition and level within the cartridge are better maintained. This invention enables extended duration printing with improved deposition stability. This provides an important tool for extending the duration and improving reliability for aerosol jet printing, a key factor for integration of aerosol jet printing in practical manufacturing operations. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743720 |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/18 (20130101) Original (OR) Class B41J 2/17566 (20130101) B41J 2/17596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213932 | AGGOUNE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (ST. MICHAEL, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KARIM AGGOUNE (AUBURN HILLS, Michigan); PETER M. OLIN (ANN ARBOR, Michigan); ZHAOXUAN ZHU (UPPER ARLINGTON, Ohio) |
| ABSTRACT | A method for controlling vehicle propulsion includes identifying at least one route characteristic of a portion of a route being traversed by a vehicle. The method further includes determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method further includes selectively adjusting a vehicle speed control input based on the target vehicle speed profile. The method further includes communicating the vehicle speed control input to a vehicle propulsion controller to achieve the target vehicle speed profile. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742204 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/12 (20160101) Original (OR) Class B60W 30/143 (20130101) B60W 30/18072 (20130101) B60W 40/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213933 | Borrelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); HYUNDAI AMERICA TECHNICAL CENTER INC. (Superior Township, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); HYUNDAI AMERICA TECHNICAL CENTER INC. (Superior Township, Michigan) |
| INVENTOR(S) | Francesco Borrelli (Kensington, California); Yongkeun Choi (Berkeley, California); Jacopo Guanetti (Berkeley, California); Yeojun Kim (Berkeley, California); Ryan Miller (Chino, California) |
| ABSTRACT | Systems, apparatus and methods for controlling a plug-in hybrid electric vehicles (PHEVs) to improve energy utilization based on vehicle-to-internet cloud (V2C) connectivity. An automated driving system is trained for predicting vehicle motion trajectories based on historical vehicle and environmental trip data. An automated powertrain control system is trained to provide a parametric approximation of long-term energy cost about the remainder of a given vehicle trip. During the trip the automated driving system plans estimated trajectories based on forecasts of power allocation, while the powertrain control system forecasts and controls the fuel burning engine, electric drive motor(s), and powertrain mode, to minimize energy-wasteful motion trajectories. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/118320 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/11 (20160101) B60W 20/12 (20160101) Original (OR) Class B60W 20/13 (20160101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2400/214 (20130101) Wireless Communication Networks H04W 4/44 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214287 | Kothandaraman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jotheeswari Kothandaraman (Richland, Washington); David J. Heldebrant (Richland, Washington); Robert A. Dagle (Richland, Washington); Yuan Jiang (Richland, Washington); Johnny Saavedra Lopez (Richland, Washington) |
| ABSTRACT | A process for producing methane or methanol includes combining a hydrogenation catalyst, hydrogen, and CO2 with a condensed phase solution comprising an amine under conditions effective to form methane or methanol, and water. A process for coproduction of methanol and a glycol includes combining an epoxide, a hydrogenation catalyst, hydrogen, and CO2 with a condensed phase solution comprising an amine under conditions effective to form methanol and a glycol. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215415 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) Original (OR) Class C07C 29/1512 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214633 | Thorson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Michael R. Thorson (Richland, Washington); Lesley J. Snowden-Swan (Ellensburg, Washington); Andrew J. Schmidt (Richland, Washington); Todd R. Hart (Kennewick, Washington); Justin M. Billing (Richland, Washington); Daniel B. Anderson (Pasco, Washington); Richard T. Hallen (Richland, Washington) |
| ABSTRACT | A hydrothermal liquefaction (HTL) system can comprise a biomass slurry source, a first pump in fluid communication with the slurry source and configured to pressurize a biomass slurry stream from the slurry source to a first pressure, a first heat exchanger in fluid communication with the first pump and configured to heat a slurry stream received from the first pump to a first temperature, a second pump in fluid communication with the first heat exchanger and configured to pressurize a slurry stream received from the first heat exchanger to a second pressure higher than the first pressure, a second heat exchanger in fluid communication with the second pump and configured to heat a slurry stream received from the second pump to a second temperature higher than the first temperature, and a HTL reactor configured to produce biocrude from a slurry stream received from the second heat exchanger. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/740339 |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/08 (20130101) C10L 9/086 (20130101) Original (OR) Class C10L 2200/0469 (20130101) C10L 2290/06 (20130101) C10L 2290/46 (20130101) C10L 2290/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214756 | Stephanopoulos |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Gregory Stephanopoulos (Winchester, Massachusetts) |
| ABSTRACT | Some aspects of this invention provide methods and bioreactors for converting a carbon source into a lipid. In some embodiments, lipid production is carried out in an aerobic fermentor and carbon dioxide generated during lipid production is converted into a carbon substrate by CO2 fixation in an anaerobic fermentor. In some embodiments, the carbon substrate generated by CO2 fixation is used as the carbon source for lipid production, thus achieving total carbon utilization in lipid production. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/074682 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 43/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/16 (20130101) C12P 7/54 (20130101) C12P 7/649 (20130101) Original (OR) Class C12P 7/6463 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214757 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Sun (Albany, California); Jian Shi (Albany, California); Blake A. Simmons (San Francisco, California); Seema Singh (Mountain House, California) |
| ABSTRACT | The present invention provides for a method of fermenting or saccharifying a biomass comprising: (a) (i) contacting a biomass comprising a polysaccharide, and an ionic liquid (IL) to form a first solution, or (ii) providing the first solution comprising the biomass and the IL, (b) contacting the first solution and carbon dioxide such that the first solution results in a lower pH, (c) introducing (i) an enzyme capable of enzymatically to breakdown at least one bond in the polysaccharide or a breakdown product of the polysaccharide, and/or (ii) a microorganism that capable of producing the enzyme and/or fermenting the polysaccharide or a breakdown product of the polysaccharide, such that the polysaccharide is at least partially broken down and the first solution is transformed into a second solution. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099488 |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 1/003 (20130101) Derivatives of Natural Macromolecular Compounds C08H 8/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/065 (20130101) C12P 7/649 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214823 | Allard, JR. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Allard, JR. (Knoxville, Tennessee); Sumit Bahl (Knoxville, Tennessee); Ryan Dehoff (Knoxville, Tennessee); Hunter Henderson (Knoxville, Tennessee); Michael Kesler (Knoxville, Tennessee); Scott McCall (Livermore, California); Peeyush Nandwana (Oak Ridge, Tennessee); Ryan Ott (Ames, Iowa); Alex Plotkowski (Knoxville, Tennessee); Orlando Rios (Knoxville, Tennessee); Amit Shyam (Knoxville, Tennessee); Zachary Sims (Knoxville, Tennessee); Kevin Sisco (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ying Yang (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence Allard, JR. (Knoxville, Tennessee); Sumit Bahl (Knoxville, Tennessee); Ryan Dehoff (Knoxville, Tennessee); Hunter Henderson (Knoxville, Tennessee); Michael Kesler (Knoxville, Tennessee); Scott McCall (Livermore, California); Peeyush Nandwana (Oak Ridge, Tennessee); Ryan Ott (Ames, Iowa); Alex Plotkowski (Knoxville, Tennessee); Orlando Rios (Knoxville, Tennessee); Amit Shyam (Knoxville, Tennessee); Zachary Sims (Knoxville, Tennessee); Kevin Sisco (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ying Yang (Knoxville, Tennessee) |
| ABSTRACT | Disclosed herein are embodiments of an Al—Ce—Mn alloy for use in additive manufacturing. The disclosed alloy embodiments provide fabricated objects, such as bulk components, comprising a heterogeneous microstructure and having good mechanical properties even when exposed to conditions used during the additive manufacturing process. Methods for making and using alloy embodiments also are disclosed herein. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/894551 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2301/052 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Alloys C22C 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215472 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); UChicago Argonne, LLC (Chicago, Illinois); The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kuan He (Evanston, Illinois); Oliver Strider Cossairt (Evanston, Illinois); Aggelos K. Katsaggelos (Chicago, Illinois); Norbert Scherer (Chicago, Illinois); Mark Hereld (Chicago, Illinois) |
| ABSTRACT | A system to generate image representations includes a first objective that receives a first light beam emitted from a sample and a second objective that receives a second light beam emitted from the sample, where the first light beam and the second light beam have conjugate phase. The system also includes a first diffractive element to receive the first light beam and separate it into a first plurality of diffractive light beams that are spatially distinct, and a second diffractive element to receive the second light beam and separate it into a second plurality of diffractive light beams that are spatially distinct. The system further includes a detector that receives the first and second plurality of diffractive light beams. The first plurality of diffractive light beams and the second plurality of diffractive light beams are simultaneously directed and focused onto different portions of an image plane of the detector. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 15/734172 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) Original (OR) Class G01B 9/02041 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) Optical Elements, Systems, or Apparatus G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215737 | MCLEOD et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | ALEXANDER SWINTON MCLEOD (New York, New York); LIN XIONG (Bronx, New York); SHUAI ZHANG (New York, New York); DIMITRI N. BASOV (New York, New York) |
| ABSTRACT | An exemplary apparatus can provide radiation to a sample(s), which can include, for example, a radiation source arrangement configured to provide radiation, a beam splitter configured to split the radiation into (i) a first radiation, and (ii) a second radiation. An optical element can also be provided which, in operation, can, e.g., (a) receive the first radiation and the second radiation, (b) reflect the first radiation as a reference radiation, (c) provide the second radiation as illumination for the sample(s), (d) receive a resultant radiation from the sample(s) that can be based on the illumination from the second radiation, and (e) provide the reference radiation and the resultant radiation to be detected and used for interferometric imaging or spectroscopy. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149236 |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 20/02 (20130101) Original (OR) Class G01Q 30/18 (20130101) G01Q 60/24 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215777 | Marple |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maxwell Marple (Berkeley, California) |
| ABSTRACT | A magic angle sample spinning nuclear magnetic resonance system including a housing, a cryogenic fluid in the housing, a magnet in the housing, a probe in the housing, a magic angle sample spinning insert in the probe, a sample battery in the magic angle sample spinning insert, a photovoltaic cell in the magic angle sample spinning insert wherein the photovoltaic cell is connected to the sample battery, an optic fiber operatively connected to the photovoltaic cell, and a laser operatively connected to the optic fiber wherein the laser provides power to charge the sample battery during the magic angle sample spinning nuclear magnetic resonance. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122233 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) G01R 33/307 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215843 | Barajas-Olalde et al. |
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| FUNDED BY |
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| APPLICANT(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | César Barajas-Olalde (Tampico, Mexico); Kyle A. Glazewski (Grand Forks, North Dakota); Nicholas W. Bosshart (Larimore, North Dakota) |
| ABSTRACT | Methods are presented for determining the location of underground features (e.g., CO2). One method includes capturing, by sensors distributed throughout a region, seismic traces associated with seismic signals generated by a seismic source. For multiple sensors, active noise is identified or passive noise is measured within each seismic trace and values for attributes associated with the active or passive noise are determined. Further, an unsupervised machine-learning model, based on the values of the attributes, is utilized to determine noise characteristics for multiple sensors. The sensors are grouped in clusters based on the noise characteristics for each sensor. For multiple clusters, a noise filter is created based on the noise characteristics of the sensors in the cluster, and the noise filter of the cluster is applied, for multiple sensors, to the seismic traces of the sensor. Additionally, the filtered seismic traces are analyzed to determine a location of CO2 underground. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116409 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/288 (20130101) G01V 1/301 (20130101) G01V 1/364 (20130101) Original (OR) Class G01V 2210/3246 (20130101) G01V 2210/3248 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216368 | GUTIERREZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony GUTIERREZ (Bellevue, Washington); Sooraj PUTHOOR (Austin, Texas) |
| ABSTRACT | A processor core is configured to execute a parent task that is described by a data structure stored in a memory. A coprocessor is configured to dispatch a child task to the at least one processor core in response to the coprocessor receiving a request from the parent task concurrently with the parent task executing on the at least one processor core. In some cases, the parent task registers the child task in a task pool and the child task is a future task that is configured to monitor a completion object and enqueue another task associated with the future task in response to detecting the completion object. The future task is configured to self-enqueue by adding a continuation future task to a continuation queue for subsequent execution in response to the future task failing to detect the completion object. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215171 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) G06F 9/545 (20130101) G06F 9/546 (20130101) G06F 9/3877 (20130101) G06F 9/4881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210216387 | LePera et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William P. LePera (Wappingers Falls, New York); Sameh Sherif Sharkawi (Cypress, Texas); Austen William Lauria (Fishkill, New York) |
| ABSTRACT | Technology for determining whether an inter-process type message has been successfully sent from a first process to a second process running on a single computer with a single processor(s) set. A variable (for example, a bit value) is used to indicate whether the inter-process message has been communicated between the processes. A timer and a predetermined timeout threshold are used to determine if the inter-process message has been pending for too long without being successfully communicated. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739613 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) G06F 11/079 (20130101) Original (OR) Class G06F 11/0724 (20130101) G06F 11/0757 (20130101) G06F 11/0772 (20130101) G06F 2209/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217712 | PAPAPOLYMEROU et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Ioannis PAPAPOLYMEROU (Okemos, Michigan); Premjeet CHAHAL (Okemos, Michigan); John D. ALBRECHT (Okemos, Michigan); Michael Thomas CRATON (Lansing, Michigan); Christopher OAKLEY (Lansing, Michigan) |
| ABSTRACT | A method of manufacturing an interconnect packaging structure is provided. In one aspect, the method includes forming a first body defining a cavity around at least one integrated circuit using an additive manufacturing machine, depositing a conductive transmission line on the first body and electrically coupling the conductive transmission line and the at least one integrated circuit with a conductive interconnect. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 17/056188 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/028 (20210501) G01S 7/282 (20130101) G01S 13/931 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) Original (OR) Class H01L 24/06 (20130101) H01L 24/19 (20130101) H01L 24/24 (20130101) H01L 2223/6627 (20130101) H01L 2223/6644 (20130101) H01L 2223/6677 (20130101) H01L 2224/06131 (20130101) H01L 2224/24227 (20130101) H01L 2224/24247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217943 | REN et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Zhifeng REN (Pearland, Texas); Jing SHUAI (Houston, Texas) |
| ABSTRACT | Systems and methods discussed herein relate to Zintl-type thermoelectric materials, including a p-type thermoelectric material according to the formula AMyXy, and includes at least one of calcium (Ca), europium (Eu), ytterbium (Yb), and strontium N (Sr), and has a ZT of the above about 0.60 above 675 K. The n-type thermoelectric component includes magnesium (Mg), tellurium (Te), antimony (Sb), and bismuth (Bi) according to the formula Mg3.2Sb1.5Bi0.5-xTex that has an average ZT above 0.8 from 400 K to 800 K. The p-type and n-type materials discussed herein may be used alone, in combination with other materials, or in combination with each other in various configurations. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999846 |
| CURRENT CPC | Alloys C22C 1/04 (20130101) C22C 12/00 (20130101) C22C 28/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217952 | Jarillo-Herrero et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong MA (Cambridge, Massachusetts); Nuh GEDIK (Watertown, Massachusetts); Suyang XU (Cambridge, Massachusetts); Zhiren ZHENG (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pablo Jarillo-Herrero (Cambridge, Massachusetts); Qiong MA (Cambridge, Massachusetts); Nuh GEDIK (Watertown, Massachusetts); Suyang XU (Cambridge, Massachusetts); Zhiren ZHENG (Cambridge, Massachusetts) |
| ABSTRACT | An ultrathin, carbon-based memristor with a moiré superlattice potential shows prominent ferroelectric resistance switching. The memristor includes a bilayer material, such as Bernal-stacked bilayer graphene, encapsulated between two layers of a layered material, such as hexagonal boron nitride. At least one of the encapsulating layers is rotationally aligned with the bilayer to create the moiré superlattice potential. The memristor exhibits ultrafast and robust resistance switching between multiple resistance states at high temperatures. The memristor, which may be volatile or nonvolatile, may be suitable for neuromorphic computing. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094141 |
| CURRENT CPC | Static Stores G11C 13/0069 (20130101) G11C 2213/35 (20130101) G11C 2213/53 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/10 (20130101) Original (OR) Class H01L 45/142 (20130101) H01L 45/143 (20130101) H01L 45/148 (20130101) H01L 45/149 (20130101) H01L 45/1206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218015 | CHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Shuru CHEN (Troy, Michigan); Fang DAI (Troy, Michigan); Mei CAI (Bloomfield Hills, Michigan) |
| ABSTRACT | The present disclosure relates to sulfur-containing electrodes and methods for forming the same. For example, the method may include disposing an electroactive material on or near a current collector to form an electroactive material layer having a first porosity and applying pressure and heat to the electroactive material layer so that the electroactive material layer has a second porosity. The first porosity is greater than the second porosity. The electroactive material may include a plurality of electroactive material particles and one or more salt additives. The method may further include contacting the electroactive material layer and an electrolyte such that the electrolyte dissolves the plurality of one or more salt particles so that the electroactive material layer has a third porosity. The third porosity may be greater than the second porosity and less than the first porosity. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743650 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/62 (20130101) H01M 4/139 (20130101) Original (OR) Class H01M 4/0404 (20130101) H01M 4/0435 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218055 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | A sulfide glass solid electrolyte sheet can be protected from reaction with moisture by a thin metal layer coating converted to a thin electrochemically functional and protective compound layer. The converted protective compound layer is electrochemically functional in that it allows for through transport of lithium ions. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/248225 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 50/403 (20210101) H01M 50/437 (20210101) H01M 50/451 (20210101) H01M 50/457 (20210101) H01M 2300/0068 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218062 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wu Xu (Richland, Washington); Ji-Guang Zhang (Richland, Washington); Hao Jia (Richland, Washington); Xianhui Zhang (Richland, Washington); Xia Cao (Richland, Washington); Sujong Chae (Richland, Washington); Ran Yi (Richland, Washington); Qiuyan Li (Richland, Washington); Won-Jin Kwak (Richland, Washington); Xiaolin Li (Richland, Washington) |
| ABSTRACT | Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, or a combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144600 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) Original (OR) Class H01M 10/0569 (20130101) H01M 2300/004 (20130101) H01M 2300/0034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218230 | BOWERS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John E. BOWERS (Santa Barbara, California); Arthur GOSSARD (Santa Barbara, California); Daehwan JUNG (Goleta, California); Kunal MUKHERJEE (Goleta, California); Justin NORMAN (Goleta, California); Jenny SELVIDGE (Goleta, California) |
| ABSTRACT | A quantum dot (QD) laser comprises a semiconductor substrate and an active region epitaxially deposited on the semi-conductor substrate. The active region includes a plurality of barrier layers and a plurality of QD layers interposed between each of the plurality of barrier layers. A net compressive strain associated with the plurality of QD layers is maintained below a maximum allowable strain to prevent formation of misfit dislocations within the active region of the QD laser. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 17/058012 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/3406 (20130101) Original (OR) Class H01S 5/3412 (20130101) H01S 5/3436 (20130101) H01S 5/34353 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218805 | Gonzalez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ASSIGNEE(S) | Intellectual Property Systems, LLC (Weston, Florida) |
| INVENTOR(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ABSTRACT | Systems and methods for reducing data movement in a computer system. The systems and methods use information or knowledge about the structure of an algorithm, operations to be executed at a receiving processing unit, variables or subsets or groups of variables in a distributed algorithm, or other forms of contextual information, for reducing the number of bits transmitted from at least one transmitting processing unit to at least one receiving processing unit or storage device. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/213012 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) Coding; Decoding; Code Conversion in General H03M 7/24 (20130101) H03M 7/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) H04L 67/104 (20130101) H04L 67/1095 (20130101) Original (OR) Class H04L 69/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20210214049 | Cardenas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Engineering Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Lee Cardenas (Framingham, Massachusetts); Michael Conry (Beverly, Massachusetts); Michael Rufo (Hanover, Massachusetts) |
| ABSTRACT | A technique for managing an attachment between first and second portions of a device. The technique includes a retaining component having a first state in which the retaining component maintains the attachment between the first and second portions by virtue of a rigid characteristic and a second state in which the retaining component loses the rigid characteristic and no longer maintains the attachment. The retaining component transitions from the first state to the second state upon exposure to liquid water. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854533 |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/003 (20130101) B63B 22/08 (20130101) Original (OR) Class Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215353 | Yashar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Anthony Yashar (Dunn Loring, Virginia) |
| ABSTRACT | A bacteria abatement water heater abates bacterial growth and includes a fluid-isolated heat exchanger; a water heating container that heats water to a high water temperature that is greater than or equal to a kill temperature for bacteria; a hot water delivery conduit including a transitional cooling zone in thermal communication with the fluid-isolated heat exchanger and that provides bacteria-free water from the water heating container at a safe temperature. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146330 |
| CURRENT CPC | Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 17/0073 (20130101) Original (OR) Class F24D 19/1051 (20130101) F24D 2220/06 (20130101) Fluid Heaters, e.g Water or Air Heaters, Having Heat Generating Means, in General F24H 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215518 | Rufo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Engineering Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Rufo (Hanover, Massachusetts); Michael Conry (Beverly, Massachusetts); Robert Watson (Lowell, Massachusetts) |
| ABSTRACT | A technique provides a modular sensing device having multiple separable modules attached end to end. The modules are selectable based on mission requirements, with different modules and combinations thereof selected for different mission types and/or requirements. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144527 |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/245 (20130101) Original (OR) Class G01D 21/02 (20130101) Electric Digital Data Processing G06F 8/61 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215599 | Forbes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented bythe Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Patrick Forbes (Elkridge, Maryland); Matthew Edward Staymates (Damascus, Maryland) |
| ABSTRACT | An infrared thermal desorber includes a desorption housing; an infrared source receiver that receives an infrared emission source; an infrared absorber receiver that receives an infrared absorber, such that the infrared absorber receiver produces thermal energy emission; an analyte target receiver that receives an analyte target, such that the analyte target receiver is in infrared communication with the infrared absorber disposed in the infrared source receiver so that the analyte target receives the thermal energy emission from the infrared absorber, desorbs the adsorbed analyte as volatilized analyte from the analyte target in response to receipt of the thermal energy emission from the infrared absorber, and communicates the volatilized analyte from the analyte target; and an effluent communicator that receives the volatized analyte. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144232 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 21/35 (20130101) Original (OR) Class G01N 21/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215636 | Claussen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); Kshama Parate (Ames, Iowa); Mark C. Hersam (Willmette, Illinois); Sonal V. Rangnekar (Chicago, Illinois) |
| ABSTRACT | Methods and systems of fabrication of high resolution, high-throughput electrochemical sensing circuits on a substrate. High resolution electrochemical sensing circuits are printed by an effective additive technique to the substrate. Optionally, post-print annealing converts electrochemically inactive printed graphene into one that is electrochemically active. The printing can be by aerosol jet printing, but is not necessarily limited thereto. An example is inkjet printing and then the post-print annealing. Ink formulation would be adjusted for effectiveness with inkjet printing. Optionally biorecognition agents can be covalently bonded to the printed graphene for the purpose of electrochemical biosensing. High throughput fabrication of high-resolution graphene circuits (feature sizes in the tens of microns <50 μm) for electrochemical biosensing is possible by chemical functionalization of the graphene surface with a biological agent. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/248211 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2001/08 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 80/00 (20141201) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) B41M 5/0023 (20130101) B41M 7/009 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4148 (20130101) Original (OR) Class G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215882 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saeed Khan (Lafayette, Colorado); Jeffrey Shainline (Boulder, Colorado) |
| ABSTRACT | A fiber-to-chip coupler includes a substrate, a waveguide on a top surface of the substrate, an optical fiber axially aligned to the waveguide, and a cap. The waveguide has a uniform region with uniform width and a tapered-waveguide region having a width that adiabatically increases from a minimum width to the uniform width. The optical fiber has a tapered fiber tip having a minimum core diameter, a cylindrical section having a maximum core diameter, and a tapered-fiber section therebetween. The optical fiber is located at least in part above the tapered-waveguide region, and has a core diameter that adiabatically decreases within a taper length of the tapered-fiber section. The cap extends from the tapered fiber tip toward the cylindrical section, is formed of a second material having a cap refractive index that exceeds a refractive index of the optical fiber, and includes a cap-region disposed on the tapered-waveguide region. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144980 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/305 (20130101) Original (OR) Class G02B 6/4214 (20130101) G02B 6/4239 (20130101) G02B 6/29335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20210213177 | Cho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Junghyun Cho (Vestal, New York) |
| ABSTRACT | A substrate subject to degradation at temperatures above 100° C. is coated with a nanostructured ceramic coating having a thickness in excess of 100 nm, formed on a surface of the substrate, wherein a process temperature for deposition of the nanostructured coating does not exceed 90° C. The coating may be photocatalytic, photovoltaic, or piezoelectric. The coating, when moistened and exposed to ultraviolet light or sunlight, advantageously generates free radicals, which may be biocidal, deodorizing, or assist in degradation of surface deposits on the substrate after use. The substrate may be biological or organic, and may have a metallic or conductive intermediate layer. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/093382 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/106 (20130101) A61L 31/16 (20130101) A61L 31/088 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 1/725 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) C08J 7/14 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213491 | Edwards et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Scott Edwards (Roanoke, Virginia); Mark Alan Mitchell (Decatur, Alabama); Eric Townsend Fox (Huntsville, Alabama) |
| ABSTRACT | A high flow differential cleaning system uses a source of pressurized compressed dry gas to pressurize a holding tank. A component to be cleaned is securely loaded and oriented against a blast plate designed specifically for the desired pressure, flow, and volume. A fast-actuated valve system opens to direct high volumes of pressurized gas from a holding tank through and around the component(s) held within the cleaning chamber for the removal of remnant powder and foreign particles from interior cavities as well as exterior component surfaces. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909572 |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 9/0328 (20130101) Original (OR) Class Servicing, Cleaning, Repairing, Supporting, Lifting, or Manoeuvring of Vehicles, Not Otherwise Provided for B60S 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210213523 | Peterson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | G. P. "Bud" Peterson (Atlanta, Georgia); Haiping Hong (Rapid City, South Dakota) |
| ABSTRACT | Disclosed herein is a method of homogeneously mixing solids, comprising: mixing, in a fluid medium, at least a first Got nanoparticle material and a surfactant, wherein the surfactant causes the first nanoparticle material to distribute uniformly in the fluid medium and have a specific charge; adding, to the fluid medium, a second nanoparticle material, wherein the surfactant has a charge of opposite polarity to the zeta potential of the second nanoparticle material; attaching the second nanoparticle material to the first Nnanoparticle material using the charge attraction of the surfactant and the second nanoparticle material to obtain a homogeneous material; and removing the attached first and second nanoparticle materials from the fluid medium to obtain a solid homogeneous material. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054202 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) Original (OR) Class B22F 1/0074 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218368 | Siles Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Jose Vicente Siles Perez (Pasadena, California); Choonsup Lee (La Palma, California); Robert H. Lin (Chino, California); Alejandro Peralta (Pasadena, California) |
| ABSTRACT | A solid-state device chip including diodes (generating a higher or lower frequency output through frequency multiplication or mixing of the input frequency) and a novel on-chip diplexing design that allows combination of two or more multiplier or mixer structures operating at different frequency bands within the 50-5000 GHz range within a same chip and/or waveguide. The on-chip diplexing design consists of a single-substrate multiplier chip with two or more multiplying structures each one containing 2 or more Schottky diodes. The diodes in each structure are tuned to one portion of the target frequency band, resulting in the two or more structures working together as a whole as a large broadband multiplier or mixer. Thus, an increase in bandwidth from 10-15% (current state-of-the-art) to at least 40% is achieved. Depending on the target frequencies, each subset of diodes within the chip can be designed to work either as a doubler or a tripler. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/093305 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 29/872 (20130101) H01L 2223/6627 (20130101) H01L 2223/6688 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 19/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218805 | Gonzalez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ASSIGNEE(S) | Intellectual Property Systems, LLC (Weston, Florida) |
| INVENTOR(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ABSTRACT | Systems and methods for reducing data movement in a computer system. The systems and methods use information or knowledge about the structure of an algorithm, operations to be executed at a receiving processing unit, variables or subsets or groups of variables in a distributed algorithm, or other forms of contextual information, for reducing the number of bits transmitted from at least one transmitting processing unit to at least one receiving processing unit or storage device. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/213012 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) Coding; Decoding; Code Conversion in General H03M 7/24 (20130101) H03M 7/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) H04L 67/104 (20130101) H04L 67/1095 (20130101) Original (OR) Class H04L 69/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20210212657 | GAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cardiac Motion, LLC (Truckee, California); The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaomeng GAO (Dublin, California); Xiaonan JIANG (Davis, California); Xiaoguang LIU (Davis, California); Dennis MATTHEWS (Meadow Vista, California); Saul SCHAEFER (Davis, California) |
| ABSTRACT | The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject\'s home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor\'s office, or hospital. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/102838 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/02 (20130101) A61B 8/04 (20130101) Original (OR) Class A61B 8/08 (20130101) A61B 8/488 (20130101) A61B 8/5207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210214282 | Temme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (Berkeley, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria\'s nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/148173 |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218805 | Gonzalez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ASSIGNEE(S) | Intellectual Property Systems, LLC (Weston, Florida) |
| INVENTOR(S) | Juan Guillermo Gonzalez (Weston, Florida); Santiago Andres Fonseca (Doral, Florida); Rafael Camilo Nunez (Aventura, Florida) |
| ABSTRACT | Systems and methods for reducing data movement in a computer system. The systems and methods use information or knowledge about the structure of an algorithm, operations to be executed at a receiving processing unit, variables or subsets or groups of variables in a distributed algorithm, or other forms of contextual information, for reducing the number of bits transmitted from at least one transmitting processing unit to at least one receiving processing unit or storage device. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/213012 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) Coding; Decoding; Code Conversion in General H03M 7/24 (20130101) H03M 7/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) H04L 67/104 (20130101) H04L 67/1095 (20130101) Original (OR) Class H04L 69/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20210215882 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Government of the United States of America as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saeed Khan (Lafayette, Colorado); Jeffrey Shainline (Boulder, Colorado) |
| ABSTRACT | A fiber-to-chip coupler includes a substrate, a waveguide on a top surface of the substrate, an optical fiber axially aligned to the waveguide, and a cap. The waveguide has a uniform region with uniform width and a tapered-waveguide region having a width that adiabatically increases from a minimum width to the uniform width. The optical fiber has a tapered fiber tip having a minimum core diameter, a cylindrical section having a maximum core diameter, and a tapered-fiber section therebetween. The optical fiber is located at least in part above the tapered-waveguide region, and has a core diameter that adiabatically decreases within a taper length of the tapered-fiber section. The cap extends from the tapered fiber tip toward the cylindrical section, is formed of a second material having a cap refractive index that exceeds a refractive index of the optical fiber, and includes a cap-region disposed on the tapered-waveguide region. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144980 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/305 (20130101) Original (OR) Class G02B 6/4214 (20130101) G02B 6/4239 (20130101) G02B 6/29335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217598 | VRIJSEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Geert VRIJSEN (Durham, North Carolina); Jungsang KIM (Chapel Hill, North Carolina); Robert SPIVEY (Durham, North Carolina); Ismail INLEK (Durham, North Carolina); Yuhi AIKYO (Durham, North Carolina) |
| ABSTRACT | Systems and methods for loading microfabricated ion traps are disclosed. Photo-ablation via an ablation pulse is used to generate a flow of atoms from a source material, where the flow is predominantly populated with neutral atoms. As the neutral atoms flow toward the ion trap, two-photon photo-ionization is used to selectively ionize a specific isotope contained in the atom flow. The velocity of the liberated atoms, atom-generation rate, and/or heat load of the source material is controlled by controlling the fluence of the ablation pulse to provide high ion-trapping probability while simultaneously mitigating generation of heat in the ion-trapping system that can preclude cryogenic operation. In some embodiments, the source material is held within an ablation oven comprising an electrically conductive housing that is configured to restrict the flow of agglomerated neutral atoms generated during photo-ablation toward the ion trap. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950703 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Electric Discharge Tubes or Discharge Lamps H01J 49/0018 (20130101) Original (OR) Class H01J 49/161 (20130101) H01J 49/422 (20130101) H01J 49/0463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20210216962 | Lawson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angela Dawn Lawson (Cambridge, Massachusetts); Fatema Momenni Kennedy (Dumfries, Virginia); Junghyun Hwang (Herndon, Virginia) |
| ABSTRACT | A system and method for tracking and managing package delivery within a distribution network. Many events happen during the processing, moving, and delivery of a package. Systems and methods herein identify whether all expected events occur, whether scan locations are correct, whether delivery times are met, and other requirements. Problems or potential problems can be identified and corrected. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/145719 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0633 (20130101) G06Q 10/0833 (20130101) Original (OR) Class G06Q 10/06393 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210218975 | Simpson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
| ABSTRACT | Embodiments of a system and method for secure processing of image data are described. Image data included in image files may be encrypted and compressed in a single step using dynamically identified compression/encryption information such as code word tables. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219353 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6209 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00456 (20130101) Pictorial Communication, e.g Television H04N 19/172 (20141101) H04N 19/182 (20141101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20210214383 | Jackson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. Jackson (Morton, Illinois); Neil P. Price (Edelstein, Illinois) |
| ABSTRACT | Disclosed are C-glycoside amine derivatives of the formula: R—CH2—C(CH3)—NH—R2 wherein R is a saccharide (e.g., as described in U.S. Pat. No. 8,314,219) and R2 is an acyl moiety derived from any ketone of the formula R3—C(O)—R3 wherein R3 is C1 to C22 straight or branched chain hydrocarbon which may be saturated or unsaturated. In addition, a method for making the C-glycoside amine derivatives involving (1) reacting a saccharide (e.g., glucose) C-glycoside ketone with a catalyst (e.g., Rh), about 10 to about 25 fold excess NH3, and an organic solvent (e.g., methanol) to form a saccharide C-glycoside amine, and (2) reacting said saccharide C-glycoside amine with a catalyst (e.g., Rh), an organic solvent (e.g., methanol), and an acyl moiety derived from any ketone of the formula R3—C(O)—R3 wherein R3 is C1 to C22 straight or branched chain hydrocarbon which may be saturated or unsaturated to form said C-glycoside amine derivative. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140415 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20210215599 | Forbes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented bythe Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Patrick Forbes (Elkridge, Maryland); Matthew Edward Staymates (Damascus, Maryland) |
| ABSTRACT | An infrared thermal desorber includes a desorption housing; an infrared source receiver that receives an infrared emission source; an infrared absorber receiver that receives an infrared absorber, such that the infrared absorber receiver produces thermal energy emission; an analyte target receiver that receives an analyte target, such that the analyte target receiver is in infrared communication with the infrared absorber disposed in the infrared source receiver so that the analyte target receives the thermal energy emission from the infrared absorber, desorbs the adsorbed analyte as volatilized analyte from the analyte target in response to receipt of the thermal energy emission from the infrared absorber, and communicates the volatilized analyte from the analyte target; and an effluent communicator that receives the volatized analyte. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144232 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 21/35 (20130101) Original (OR) Class G01N 21/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20210213101 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Chenying Guo (Malden, Massachusetts) |
| ABSTRACT | Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070596 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/708 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/7004 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/18 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 38/30 (20130101) A61K 38/1738 (20130101) A61K 38/1841 (20130101) A61K 38/2278 (20130101) A61K 45/06 (20130101) A61K 49/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20210215098 | GREENE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | CHRISTOPHER BRITTON GREENE (Hebron, Connecticut); Stuart S. Ochs (Coventry, Connecticut) |
| ABSTRACT | A diffuser may comprise an inlet and an outlet. The inlet may comprise an arcuate shape. The outlet may comprise an annular shape. The diffuser may transition from the arcuate shape at the inlet to the annular shape at the outlet. The diffuser may comprise a radially inner wall and a radially outer wall disposed opposite the radially inner wall. The radially inner wall and the radially outer wall may partially define a duct. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743966 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/02 (20130101) B64D 2033/0273 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/04 (20130101) Original (OR) Class Jet-propulsion Plants F02K 7/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/51 (20130101) F05D 2250/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210215779 | BULATOWICZ |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MICHAEL D. BULATOWICZ (SUN PRAIRIE, Wisconsin) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (FALLS CHURCH, Virginia) |
| INVENTOR(S) | MICHAEL D. BULATOWICZ (SUN PRAIRIE, Wisconsin) |
| ABSTRACT | One embodiment includes a heater system. The system includes a current source configured to generate an input current and to receive a return current. The system also includes a heater configured to generate heat in response to the input current. The system further includes a plurality of current lead wires interconnecting the current source and the heater and being configured to provide the input current to the heater and to conduct the return current from the heater. Each of the plurality of current lead wires is arranged on a separate substrate layer such that each of the plurality of current lead wires are each spaced apart from each other. At least one of the input current and the return current is divided to be conducted on two or more of the plurality of current lead wires. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741302 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) G01R 33/3804 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/03 (20130101) H05B 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210217949 | KIRBY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHRISTOPHER F. KIRBY (GAMBRILLS, Maryland); MICHAEL RENNIE (ASHLAND, Virginia); DANIEL J. O\'DONNELL (LINTHICUM, Maryland); AURELIUS L. GRANINGER (SYKESVILLE, Maryland); AARON A. PESETSKI (GAMBRILLS, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (FALLS CHURCH, Virginia) |
| INVENTOR(S) | CHRISTOPHER F. KIRBY (GAMBRILLS, Maryland); MICHAEL RENNIE (ASHLAND, Virginia); DANIEL J. O\'DONNELL (LINTHICUM, Maryland); AURELIUS L. GRANINGER (SYKESVILLE, Maryland); AARON A. PESETSKI (GAMBRILLS, Maryland) |
| ABSTRACT | A method of forming a superconductor structure is disclosed. The method comprises forming a superconductor line in a first dielectric layer, forming a resistor with an end coupled to an end of the superconductor line, and forming a second dielectric layer overlying the resistor. The method further comprises etching a tapered opening through the second dielectric layer to the resistor, and performing a contact material fill with a normal metal material to fill the tapered opening and form a normal metal connector coupled to the resistor. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738790 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/5228 (20130101) H01L 23/53242 (20130101) H01L 39/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, July 15, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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