FedInvent™ Patent Applications
Application Details for Thursday, August 12, 2021
This page was updated on Friday, August 13, 2021 at 03:26 AM GMT
Department of Health and Human Services (HHS)
| US 20210244280 | BLAAUW et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. BLAAUW (Ann Arbor, Michigan); Jamie PHILLIPS (Ann Arbor, Michigan); Cynthia Anne CHESTEK (Ann Arbor, Michigan); Taekwang JANG (Ann Arbor, Michigan); Hun-Seok KIM (Ann Arbor, Michigan); Dennis SYLVESTER (Ann Arbor, Michigan); Jongyup LIM (Ann Arbor, Michigan); Eunseong MOON (Ann Arbor, Michigan); Michael BARROW (Ann Arbor, Michigan); Samuel NASON (Ann Arbor, Michigan); Julianna RICHIE (Ann Arbor, Michigan); Paras PATEL (Ann Arbor, Michigan) |
| ABSTRACT | A mote includes an optical receiver that wirelessly receives a power and data signal in form of NIR light energy within a patient and converts the NIR light energy to an electrical signal having a supply voltage. A control module supplies the supply voltage to power devices of the mote. A clock generation circuit locks onto a target clock frequency based on the power and data signal and generates clock signals. A data recovery circuit sets parameters of one of the devices based on the power and data signal and a first clock signal. An amplifier amplifies a neuron signal detected via an electrode inserted in tissue of the patient. A chip identifier module, based on a second clock signal, generates a recorded data signal based on a mote chip identifier and the neuron signal. A driver transmits the recorded data signal via a LED or a RF transmitter. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173976 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0017 (20130101) Original (OR) Class A61B 5/0031 (20130101) A61B 5/37 (20210101) A61B 5/384 (20210101) A61B 2560/0219 (20130101) Transmission H04B 10/80 (20130101) H04B 10/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244307 | Neu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body (Denver, Colorado); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Corey P. Neu (Boulder, Colorado); Robert L. Wilson (Boulder, Colorado); David Reiter (Decatur, Georgia) |
| ABSTRACT | A process for more sensitive characterization of tissue composition for generating a quantitative MRI (qMRI) map and corresponding delta analysis. Intervertebral disc degeneration (IVDD), resulting in the depletion of hydrophilic glycosaminoglycans (GAGs) located in the nucleus pulposus (NP), can lead to debilitating neck and back pain. Magnetic Resonance Imaging (MRI) is a promising means of IVD assessment due to the correlation between GAG content and MRI relaxation values. T1 and T2 relaxation data were obtained from healthy cervical IVDs, and relaxation data was modeled using both conventional and stretched exponential (SE) decays. Normalized histograms of the resultant quantitative MRI (qMRI) maps were fit with stable distributions. SE models fit relaxation behavior with lower error compared to monoexponential models, indicating anomalous relaxation behavior in healthy IVDs. SE model parameters T1 and T1 increased with IVD segment, while conventional monoexponential measures did not vary. The improved model fit and correlation between both SE T1 and T1 with IVD level suggests these parameters are more sensitive biomarkers for detection of GAG content variation. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 17/259134 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/0515 (20130101) A61B 5/742 (20130101) A61B 5/4566 (20130101) A61B 2560/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244346 | Barton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer Barton (Tucson, Arizona); Urs Utzinger (Tucson, Arizona); Tyler Tate (Tucson, Arizona); Maureen Keenan (Tucson, Arizona); John Forbes Black (Bainbridge Island, Washington) |
| ABSTRACT | A falloposcope is described, and a method of screening a patient for fallopian tube and/or ovarian cancer with the falloposcope. The falloposcope can perform optical imaging, including fluorescence imaging and/or optical coherence tomography (OCT), and optionally include a channel for a sampling wire, within a diameter of about 0.7 millimeter. The method includes inserting the falloposcope through a lumen of vagina, cervix, uterus, and fallopian tube so a tip of the falloposcope is in proximity to a first fallopian tube or ovary of the patient; providing fluorescence stimulus wavelength through an illumination fiber of the falloposcope while imaging light at fluorescence emission wavelength through a coherent fiber bundle to form fluorescence emissions images; and determining suspect tissue. Then the sampling wire is used to collect cells from the suspect tissue for karyotype and other analysis. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195221 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/07 (20130101) A61B 1/0057 (20130101) A61B 1/063 (20130101) A61B 1/0125 (20130101) A61B 1/303 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/4325 (20130101) Original (OR) Class A61B 10/04 (20130101) A61B 10/0291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244659 | Myung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. Government Represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Myung (Stanford, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/251605 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0051 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244668 | Loscalzo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Loscalzo (Dover, Massachusetts); Ying-Yi Zhang (Quincy, Massachusetts) |
| ABSTRACT | The present application provides a method of making a particle comprising (i) obtaining a first solution comprising a negatively charged polysaccharide; (ii) obtaining a second solution comprising a positively charged polysaccharide; and (iii) mixing the first solution and the second solution to obtain a suspension comprising the particle. The present application also provides a method of making a therapeutic particle, comprising: (i) obtaining a solution comprising a therapeutic protein; (ii) obtaining a first suspension comprising the particle comprising a negatively charged polysaccharide and a positively charged polysaccharide, and (iii) mixing the solution of the therapeutic protein and the first suspension to obtain a second suspension comprising the therapeutic particle. The present application also provides particles (e.g., therapeutic particles) prepared by any one of the disclosed methods, as well as the compositions comprising such particles, and methods of treating a disease or condition using such particles and compositions. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 16/322669 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) A61K 9/1676 (20130101) Original (OR) Class A61K 38/47 (20130101) A61K 38/185 (20130101) A61K 38/195 (20130101) A61K 38/204 (20130101) A61K 38/1825 (20130101) A61K 38/1866 (20130101) A61K 38/1875 (20130101) A61K 47/61 (20170801) A61K 47/6941 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244686 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuedong Liu (Niwot, Colorado); Douglas Chapnick (Boulder, Colorado); William Old (Boulder, Colorado) |
| ABSTRACT | The invention includes the use of cannabidiol (CBD), and cannabidiol analogs, as therapeutic compounds or formulations for the increase of lipid order in the cell membranes of a patient. This increase in membrane lipid order may cause downstream therapeutic effects that may ameliorate certain disease conditions such as cardio vascular disease, high-cholesterol and Alzheimer's disease. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 17/255214 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/09 (20130101) A61K 31/13 (20130101) A61K 31/27 (20130101) A61K 31/55 (20130101) A61K 31/192 (20130101) A61K 31/352 (20130101) A61K 31/445 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244694 | Weimbs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Thomas Weimbs (Santa Barbara, California); Jacob Torres (Santa Barbara, California) |
| ABSTRACT | Compositions and methods for supporting health, especially renal health, comprising ketonic agents that recapitulate beneficial effects of ketosis by exogenously administered agents. The agents include BHB, analogs thereof, and GPR109A agonists. The agents may further include crystal precipitation inhibitors which synergistically improve treatment of certain renal conditions. The agents may be used in dietary supplements and therapeutic compositions for the treatment of cystic kidney diseases such as polycystic kidney disease, ciliopathies, and other conditions. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/240410 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/20 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/047 (20130101) A61K 31/194 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244695 | Weimbs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Augusta University Research Institute (Augusta, Georgia) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Augusta University Research Institute (Augusta, Georgia) |
| INVENTOR(S) | Thomas Weimbs (Santa Barbara, California); Jacob Torres (Santa Barbara, California); Muthusamy Thangaraju (Evans, Georgia) |
| ABSTRACT | Compositions and methods for supporting health, especially renal health, comprising ketonic agents that recapitulate beneficial effects of ketosis by exogenously administered agents. The agents include BHB, analogs thereof, and GPR109A agonists. The agents may further include crystal precipitation inhibitors which synergistically improve treatment of certain renal conditions. The agents may be used in dietary supplements and therapeutic compositions for the treatment of cystic kidney diseases such as polycystic kidney disease, ciliopathies, and other conditions. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/240605 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/20 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/047 (20130101) A61K 31/194 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244721 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jun Wang (Tucson, Arizona); Rami Ghassan Musharrafieh (Tucson, Arizona); Chunlong Ma (Tucson, Arizona); Jiantao Zhang (Tucson, Arizona); Yanmei Hu (Tucson, Arizona) |
| ABSTRACT | This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinoline (or similar) structure which function as antagonists of androgen receptor activity, and their use as therapeutics for the treatment of cancer (e.g., castration-resistant prostate cancer) and other conditions characterized with androgen receptor activity and/or androgen receptor expression. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162670 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/4709 (20130101) A61K 31/4748 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244734 | Nath et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karl A. Nath (Rochester, Minnesota); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials for improving arteriovenous fistula (AVF) maturation and/or maintaining AVF functionality. For example, methods and materials for using one or more senolytic agents to improve AVF maturation, to maintain AVF functionality, and/or to maintain the patency of an AVF are provided. Methods and materials for using one or more senolytic agents to maintain functionality and/or patency of a venous graft (e.g., a venous graft that bypasses an occluded artery) also are provided. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/973723 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/355 (20130101) A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244740 | PLEMPER et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard PLEMPER (Atlanta, Georgia); Julien SOURIMANT (Atlanta, Georgia); Edgars JECS (Decatur, Georgia); Dennis LIOTTA (Atlanta, Georgia); Stephen PELLY (Atlanta, Georgia); Robert WILSON (Ganesvoort, New York); Zackery Will DENTMON (East Point, Georgia) |
| ABSTRACT | Disclosed herein are compounds having antiviral activity, and, in particular, an inhibitory activity on the replication of Respiratory Syncytial Virus (RSV). Druggable target sites, including Px, in the RSV N protein are disclosed, as well as compounds targeting Px. The compounds can be used to treat patients with RSV infection. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 17/052595 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 311/16 (20130101) C07D 311/18 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244748 | KAMBAYASHI |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taku KAMBAYASHI (Malvern, Pennsylvania) |
| ABSTRACT | The present invention includes a method of suppressing systemic immune response in a subject, the method comprising topically administering a pharmaceutically effective amount of a vitamin D analog to a subject in need thereof. The present invention further includes a method of treating an autoimmune disease in a subject, the method comprising topically administering a pharmaceutically effective amount of a vitamin D analog to a subject in need thereof. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/227598 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/593 (20130101) Original (OR) Class A61K 38/32 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244754 | Hirano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michio Hirano (New York, New York); Caterina Garone (Cambridge, United Kingdom); Ramon Marti (Barcelona, Spain) |
| ABSTRACT | The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxynucleoside, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine (dT) or deoxycytidine (dC), or mixtures thereof. This administration of deoxynucleosides is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242822 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/513 (20130101) A61K 31/708 (20130101) A61K 31/7068 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 31/7076 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244764 | NGO et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | John T. NGO (Cambridge, Massachusetts); Jeffrey Blye MCMAHAN (Boston, Massachusetts) |
| ABSTRACT | Described herein are polypeptides, systems, and methods that relate to using domains that bind specifically to a biotinylamide to control receptor and cellular activity. |
| FILED | Tuesday, February 09, 2021 |
| APPL NO | 17/171329 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) C07K 16/44 (20130101) C07K 16/2809 (20130101) C07K 16/2818 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/60 (20130101) C07K 2319/71 (20130101) C07K 2319/74 (20130101) C07K 2319/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244802 | Nelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Daniel C. Nelson (Rockville, Maryland); Irina V. Etobayeva (Kensington, Maryland) |
| ABSTRACT | The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces, including an isolated polypeptide comprising an enzymatically active domain (EAD) of a Bacillus bacteriophage endolysin. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/054539 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) Original (OR) Class A61K 38/162 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244822 | DeAngelis |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma) |
| ABSTRACT | Described herein are compositions such as antibody-drug conjugates that include a heparosan polymer. In some embodiments, a targeting moiety is bound to an end of the heparosan polymer or to an internal monomeric subunit of the heparosan polymer. In some embodiments, a payload molecule is bound to an end of the heparosan or to an internal monomeric subunit. Some embodiments relate to methods of making and using the compositions. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 17/251147 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244824 | PEI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dehua PEI (Columbus, Ohio); Marina BUYANOVA (Columbus, Ohio); Ziqing QIAN (Wellesley, Massachusetts) |
| ABSTRACT | The present disclosure provides for polypeptide conjugates. The polypeptide conjugates disclosed herein comprise a polyarginine peptide and a cyclic cell-penetrating peptide (cCPP) conjugated, directly or indirectly, to the polyarginine peptide. The present disclosure demonstrates that cCPPs conjugated to polyarginine peptides can be used to deliver nucleic acids to the cytosol of cells. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 17/257224 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6455 (20170801) Original (OR) Class Peptides C07K 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244826 | Thaxton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | C. Shad Thaxton (Chicago, Illinois); Kaylin M. McMahon (Chicago, Illinois) |
| ABSTRACT | Nanostructures for the systemic delivery of nucleic acids, such as RNA, are provided herein. The nanostructures include templated lipoprotein nanoparticles (TLPs) composed of a core decorated with proteins, a lipid bilayer and hydrophobic molecules that self-assemble with nucleic acids, such as RNA. The nanostructures are useful for research, therapeutic and diagnostic applications. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/221867 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 47/183 (20130101) A61K 47/6929 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244830 | CONDEELIS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); MONTEFIORE MEDICAL CENTER (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John CONDEELIS (Bronx, New York); Craig BRANCH (Bronx, New York); Maja OKTAY (Bronx, New York) |
| ABSTRACT | Methods are provided for measuring the activity of TMEM sites in a tumor comprising measuring a transient increase in permeability of blood vessels at TMEM sites that allows tumor cells to enter the blood vessels, wherein permeability is measured using a modality selected from the group consisting of MRI, PET, CT, and SPECT, and wherein a transient increase in permeability indicates that a TMEM site is active. The method can include, for example, obtaining a MenaINV score assessed by fine needle aspiration in the same tissue. The present invention can be used as both a prognostic for dissemination and a predictive end point for identification and validation of dissemination inhibitors/anti-metastasis drugs. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/972798 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/105 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244831 | Steinmetz |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California) |
| ABSTRACT | A nanoparticle for diagnostic, therapeutic, and/or theranostic applications includes a rod-shaped plant virus like particle (VLP), one or more gadolinium T1 contrast agents conjugated to an interior surface of the VLP, and a layer of polydopamine (PDA) coated over a portion of the exterior surface of the VLP. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/129490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0052 (20130101) A61K 49/108 (20130101) A61K 49/1896 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244850 | Bellas et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evangelia Bellas (Philadelphia, Pennsylvania); Kacey Marra (Canonsburg, Pennsylvania); J. Peter Rubin (Pittsburgh, Pennsylvania); David L. Kaplan (Concord, Massachusetts); James J. Yoo (Winston-Salem, North Carolina) |
| ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection) and/or be molded flexibly into a tissue void of any shape and/or size. In some embodiments, the composition described herein comprises a plurality of silk fibroin particles, which can retain their original volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091835 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244851 | Shen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jie Shen (St. Louis, Missouri); Jianjun Guan (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Jie Shen (St. Louis, Missouri); Jianjun Guan (St. Louis, Missouri) |
| ABSTRACT | Methods and formulations for promoting the healing of fracture nonunion sites under inflammatory conditions. The formulation includes a flexible biodegradable scaffold loaded with therapeutically effective amounts of CXCL12 and SPPI encapsulated in biodegradable microspheres. The method includes applying the formulation directly to a region of a fracture nonunion to effect sustained local release of the therapeutically effective amounts of CXCL12 and SPPI to the fracture nonunion region. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170310 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/58 (20130101) A61L 27/227 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244911 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky); W-Z Biotech, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dongfang Wang (Lexington, Kentucky); Joseph B. Zwischenberger (Lexington, Kentucky); Guangfeng Zhao (Shenzhen, China PRC); Cherry Ballard-Croft (Lexington, Kentucky) |
| ABSTRACT | A multiple lumen device for percutaneous left ventricular unloading during venoarterial extracorporeal membrane oxygenation comprising: an expandable cage, an outer catheter, and an inner catheter, wherein a proximal end of the expandable cage is attached to the outer catheter and a distal end of the expandable cage is attached to the inner catheter, such that when the proximal end of the inner catheter is retracted, the cage moves from a compressed configuration to an expanded configuration is described. Also provided are methods for causing the blood of a subject to flow in a retrograde manner using a multiple lumen device. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232594 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/003 (20130101) Original (OR) Class A61M 25/0074 (20130101) A61M 2025/0002 (20130101) A61M 2025/0031 (20130101) A61M 2205/0216 (20130101) A61M 2205/3331 (20130101) A61M 2210/125 (20130101) A61M 2210/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246099 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig J. Thomas (Gaithersburg, Maryland); Patrick Joseph Morris (Laurel, Maryland); Richard Andrew Castledine (Northumberland, United Kingdom); Samuel Lawrence Bourne (Northumberland, United Kingdom) |
| ABSTRACT | A process for the preparation of (2R, 6R)-hydroxynorketamine is provided. The process requires no chromatography purification and affords the (2R, 6R)-hydroxynorketamine in eight steps with a 26% overall yield and greater than 97% purity. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 15/734710 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic or Carbocyclic Compounds C07C 221/00 (20130101) Original (OR) Class C07C 249/02 (20130101) C07C 269/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246109 | Glazer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edith C. Glazer (Lexington, Kentucky); David K. Heidary (Lexington, Kentucky) |
| ABSTRACT | Inhibitors of the enzyme cytochrome P450 (CYP), including 1B1 (CYP1B1), 1A1 (CYP1A1) and 19A1 (CYP19A1) are provided, and are useful in medical applications. Disclosed are highly potent and selective compounds that can be used in chemoprevention to ameliorate malignant changes induced by CYP, or to aid in treatment, including restoration of chemotherapeutic efficacy. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/174336 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Acyclic or Carbocyclic Compounds C07C 43/285 (20130101) C07C 255/16 (20130101) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 213/30 (20130101) C07D 213/56 (20130101) C07D 215/14 (20130101) C07D 235/18 (20130101) C07D 239/26 (20130101) C07D 239/74 (20130101) C07D 277/24 (20130101) Original (OR) Class C07D 277/28 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246125 | Moghadam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 712 North, Inc. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcel Victor Alavi Khorassani Moghadam (San Francisco, California) |
| ABSTRACT | Pyranone compounds are disclosed herein, which were quite surprisingly found as having OMA1 and/or OPA1 modulatory properties. Compounds of present invention may provide useful for the treatment of certain conditions and diseases, which are amenable to OMA1 and/or OPA1-modulatory therapies. Such conditions may include conditions and diseases prevalent in the elderly, such as cancer and Alzheimer's disease. Pharmaceutical compositions comprising compounds of present invention may be combined with other treatments or further comprise other pharmaceutically active ingredients. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/156237 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0073 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246137 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); Loyola University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); Loyola University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Wenwei Huang (Rockville, Maryland); Hao Li (Rockville, Maryland); Wei Sun (Germantown, Maryland); Xiuli Huang (Potomac, Maryland); Paresma R. Patel (Rockville, Maryland); Hangmao Sun (Germantown, Maryland); Wei Zheng (Potomac, Maryland); Xiao Lu (Rockville, Maryland); Philip E. Sanderson (Bethesda, Maryland); Myunghoon Kim (Olympia, Washington); Meghan J. Orr (Nashville, Illinois); Gregory J. Tawa (Doylestown, Pennsylvania); Kim C. Williamson (Bethesda, Maryland) |
| ABSTRACT | Disclosed are compounds of formula (I) and formula (II): wherein R1, R2, A, and B are as defined herein. Also disclosed is a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula (I) or (II) either alone or in combination with a second compound selected from elesclomol, NSC174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237351 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 487/08 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246140 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhaoda Zhang (Andover, Massachusetts); Baohui Zheng (Boston, Massachusetts); Gengyang Yuan (Boston, Massachusetts); Ramesh Neelamegam (Boston, Massachusetts); Anna-Liisa Brownell (Salem, Massachusetts) |
| ABSTRACT | The present application provides a compound of Formula: or a pharmaceutically acceptable salt thereof, wherein ring B, L1, ring A, L2, n, R1, R2, R3, R4, and X1 are as described herein. Pharmaceutical compositions comprising the compound, as well as the methods of making and using the compound, are also provided. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162614 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0455 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 471/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246141 | Gangjee |
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| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | A compound of Formula II, or optionally a salt or a hydrate of the compound of Formula II is provided: wherein R1 is selected from the group consisting of a hydrogen, an alkyl group having from one to six carbon atoms, an aryl group, and a heteroaryl group; R2 is selected from the group consisting of an alkyl group having from one to six carbon atoms, a hydrogen, a NRaRb group wherein Ra is either a hydrogen or an alkyl group having from one to six carbon atoms and Rb is either a hydrogen or an alkyl group having from one to six carbon atoms, an aryl group, a heteroaryl group, and a halogen; R is an alkyl group having from one to six carbon atoms; and Ar is selected from the group consisting of an alkyl group having from one to six carbon atoms, a substituted aryl, and a substituted heteroaryl. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 16/949519 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246170 | LANGEDIJK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Janssen Pharmaceuticals, Inc. (Titusville, New Jersey); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Johannes Petrus Maria LANGEDIJK (Amsterdam, Netherlands); Lucy RUTTEN (Rijnsburg, Netherlands); Mark Johannes Gerardus BAKKERS (Haarsteeg, Netherlands); Rinke BOS (Oegstgeest, Netherlands); Frank WEGMANN (Leiden, Netherlands); David Adrianus Theodorus Maria ZUIJDGEEST (Den Haag, Netherlands); Dan H. BAROUCH (Newton, Massachusetts); An VANDEBOSCH (Herentals, Belgium); Mathieu Claude Michel le GARS (Antwerp, Belgium); Jerald C. SADOFF (Washington, D.C., None) |
| ABSTRACT | The invention relates to immunogenic compositions and vaccines containing a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; also referred to as SARS-CoV-2)) protein or a polynucleotide encoding a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) protein and uses thereof. The invention also provides methods of treating and/or preventing a coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) infection by administering an immunogenic composition or vaccine to a subject (e.g., a human). The invention also provides methods of detecting and/or monitoring a protective anti-coronavirus (e.g., Wuhan coronavirus (2019-nCoV; SARS-CoV-2)) antibody response (e.g., anti-coronavirus antibody response, e.g., anti-2019-nCoV antibody response, e.g., anti-Spike antibody response, e.g., anti-Spike neutralizing antibody response). The present invention relates to isolated nucleic and/or recombinant nucleic acid encoding a coronavirus S protein, in particular a SARS-CoV-2 S protein, and to the coronavirus S proteins, as well as to the use of the nucleic acids and/or proteins thereof in vaccines. |
| FILED | Saturday, January 30, 2021 |
| APPL NO | 17/163357 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246180 | Jaffrey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samie R. Jaffrey (New York, New York); Ulrich Hengst (New York, New York) |
| ABSTRACT | The invention relates to expressing proteins in the axons of mammalian neurons. The invention provides nucleic acids that can be used to express a selected polypeptide in neuronal axons, viruses that can be used deliver nucleic acids of the invention into neuronal axons, as well as methods for doing so. Thus, the invention provides pharmaceutical compositions comprising viruses of the invention, as well as their use in methods of treating injured axons or conditions associated with aberrant axon growth or function. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/168774 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0075 (20130101) Peptides C07K 14/4705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2770/36143 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246186 | Roybal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kole T. Roybal (San Francisco, California); Raymond Liu (San Francisco, California); Iowis Zhu (San Francisco, California) |
| ABSTRACT | The present disclosure generally relates to, among other things, a new class of receptors engineered to modulate transcriptional regulation in a ligand-dependent manner. Particularly, the new receptors, even though derived from Notch, do not require the Notch negative regulatory regions previously believed to be essential for the functioning of the receptors. The disclosure also provides compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating an activity of a cell and/or for the treatment of various health conditions or diseases, such as cancers. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217635 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/09 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246202 | LONGO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valter D. LONGO (Playa del Rey, California); Jaime GUEVARA (Aventura, Florida) |
| ABSTRACT | A method for alleviating a symptom of chemotherapy in a subject comprises identifying a subject undergoing chemotherapy and then administering a therapeutically effective amount of a GH/IGF-1 Axis inhibitory composition to the subject. Typically, the levels of IGF-1 and/or GH in the subject are monitored as well as chemotherapy related symptoms. A method of alleviating oxidative damage, cellular damage including mutations, and insulin resistance in a subject is also provided. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/175393 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/27 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/26 (20130101) Original (OR) Class C07K 16/2863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246211 | Goldberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Michael Solomon Goldberg (Brookline, Massachusetts); Chun Gwon Park (Seoul, South Korea) |
| ABSTRACT | Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices. |
| FILED | Tuesday, April 27, 2021 |
| APPL NO | 17/241935 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 31/444 (20130101) A61K 31/635 (20130101) A61K 31/4745 (20130101) A61K 38/19 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 16/2896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246226 | BAUM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regeneron Pharmaceuticals, Inc. (TARRYTOWN, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alina BAUM (Pleasantville, New York); Christos KYRATSOUS (Irvington, New York); Lisa PURCELL (Yorktown Heights, New York) |
| ABSTRACT | The present disclosure provides antibodies and antigen-binding fragments thereof that bind specifically to TMPRSS2 and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., coronavirus infections or influenza virus infections). |
| FILED | Tuesday, February 09, 2021 |
| APPL NO | 17/171941 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246409 | MCCARTHY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Kevin J. MCCARTHY (Shreveport, Louisiana); Deborah MCCARTHY (Shreveport, Louisiana) |
| ABSTRACT | The presently disclosed invention relates to methods of creating a laminar and shear stress environment for cells and Multidirectional Shear Stress Apparatuses comprising a baseplate, a dish attached to the baseplate, a motor attached to the baseplate, the motor turning a shaft, a cone functionally and rotationally attached to the shaft, a first plurality of wells defined in the baseplate to receive coverslips |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/210394 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/04 (20130101) Original (OR) Class C12M 41/12 (20130101) C12M 41/34 (20130101) C12M 41/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246411 | SIERAD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CLEMSON UNIVERSITY RESEARCH FOUNDATION (Clemson, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | LESLIE SIERAD (CENTRAL, South Carolina); CHRISTOPHER DELANEY (WINSTON-SALEM, North Carolina); RICHARD PASCAL, III (CHAPIN, South Carolina); DAN SIMIONESCU (PENDLETON, South Carolina); AGNETA SIMIONESCU (PENDLETON, South Carolina) |
| ABSTRACT | Bioreactors and components of bioreactors are described as may be beneficially utilized in development and conditioning of cellular materials for study or implant. The bioreactors are modular, and components of the bioreactors can be easily assembled with alternatives provided to develop specific, predetermined conditioning environments for cellular materials (e.g., implantable tissue). By selection of one of multiple alternative compliance chambers, a bioreactor can be utilized to condition tissue in a low-pressure circuit (e.g., a pulmonary heart circuit), and by utilization of an alternative compliance chamber, the bioreactor can instead condition tissue in a high-pressure circuit (e.g., an aortic heart circuit). |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244447 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/00 (20130101) C12M 23/44 (20130101) C12M 29/00 (20130101) C12M 29/12 (20130101) C12M 35/04 (20130101) C12M 41/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246432 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin); The University of Tokyo (Tokyo, Japan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Yuri Furusawa (Tokyo, Japan); Seiya Yamayoshi (Kanagawa, Japan) |
| ABSTRACT | Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155625 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) A61K 2039/5252 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246439 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Breanna E. DiAndreth (Cambridge, Massachusetts); Noreen Wauford (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure, at least in part, provides RNA cleavage based engineered bi-stable toggle switch utilizing the Programmable Endonucleolytic Scission-Induced Stability Tuning (PERSIST) platform. Also provided herein, are vectors encoding the engineered bi-stable toggle switch, and uses thereof. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122087 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/1024 (20130101) Original (OR) Class C12N 2310/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246440 | St. Onge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert P. St. Onge (Palo Alto, California); Ulrich Schlecht (Palo Alto, California); Sasha F. Levy (Stony Brook, New York); Ronald W. Davis (Palo Alto, California); Joseph Horecka (Fremont, California) |
| ABSTRACT | A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997586 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1031 (20130101) C12N 15/1034 (20130101) C12N 15/1037 (20130101) Original (OR) Class C12N 15/1058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246442 | Rivera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Juan Rivera (Mechanicsburg, Pennsylvania); Nicolas Charles (Asnieres Sur Seine, France) |
| ABSTRACT | The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162982 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/675 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 39/395 (20130101) A61K 39/39533 (20130101) A61K 39/39566 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/4291 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246446 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aiming YU (Granite Bay, California); Pui Yan HO (Davis, California); Meijuan TU (Davis, California); Joseph L. JILEK (Davis, California); Qianyu ZHANG (Davis, California); Hannah E. PETREK (Davis, California) |
| ABSTRACT | Provided are hybrid tRNA/pre-miRNA molecules, e.g., comprising a single tRNA and one, two or more pre-miRNA molecules, useful for the production and therapeutic delivery of an inserted RNA sequence, e.g., one or more miRNAs. Also provided are liposomes and nanoparticles that include the hybrid tRNA/pre-miRNA molecules. Methods of treating cancer by administration of the hybrid tRNA/pre-miRNA molecules are also provided. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 17/056203 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6911 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246454 | LYKENS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LifeSplice Pharma LLC (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole M. LYKENS (Malvern, Pennsylvania); Gordon J. LUTZ (Malvern, Pennsylvania); Melanie K. TALLENT (Malvern, Pennsylvania) |
| ABSTRACT | The invention provides splice modulating oligonucleotides (SMOs) designed to modulate the splicing of a RAGE pre-mRNA, compositions including the SMOs, and methods of treating and preventing diseases and conditions using the SMOs and compositions. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/056368 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2207/15 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246455 | DE ABREU RIBEIRO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cairn Biosciences, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M. Susana G. DE ABREU RIBEIRO (San Francisco, California); Catherine I. LACAYO (Fremont, California); Mary J. C. LUDLAM (San Francisco, California) |
| ABSTRACT | The present invention provides assays for profiling two or more polypeptides in live cells. In some embodiments, the invention provides multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells. Methods of making multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Libraries and kits comprising multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Methods of profiling/assaying the multireporter cells and multireporter cell libraries are provided. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/614297 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 15/1093 (20130101) C12N 2830/20 (20130101) C12N 2840/002 (20130101) C12N 2840/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246494 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for methods of epigenetic analysis. In some cases, the methods may include obtaining a sample comprising a nucleic acid sequence. In some cases, the nucleic acid sequence may comprise one or more epigenetic marks. The methods may include performing a sequencing. The methods may include distinguishing a hydroxymethylated base from a methylated base. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231671 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2501/70 (20130101) C12N 2501/71 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246496 | FAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Saint Louis University (St. Louis, Missouri) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Xiaofeng FAN (St. Louis, Missouri); Adrian Michael DI BISCEGLIE (St. Louis, Missouri) |
| ABSTRACT | Provided herein are methods of preparing a template nucleic acid for next-generation sequencing. The methods comprise performing primer extension using c7dGTP instead of dGTP, which then allows for the input nucleic acids to be selectively digested by c7dGTP-resistant restriction enzymes, thereby enriching the template nucleic acid prior to next-generation sequencing library preparation. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173858 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6848 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246502 | HANAGE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | William HANAGE (Cambridge, Massachusetts); Karel BRINDA (Brighton, Massachusetts); Michael Hartmann BAYM (Cambridge, Massachusetts) |
| ABSTRACT | Surveillance of circulating drug resistant bacteria is essential for healthcare providers to deliver effective empiric antibiotic therapy. However, molecular epidemiology does not occur on a timescale that is optimal for guiding patient treatment. Here the Inventors present a method called neighbor typing for inferring characteristics of an unknown bacterial sample by identifying the its closest relative in a database of known genomes. The Inventors demonstrate an implementation of this principle using sequence k-mer content, to identify both the closest relative and a phenotype of interest, in this case drug resistance. The Inventors show for the examples of S. pneumoniae and N. gonorrhoeae that this technique can be applied to data from an Oxford Nanopore device in real time and is capable of identifying the presence of a known resistant strain in 5 minutes of sequencing and 4 hours from sample collection, even from a clinical metagenomic sample. This flexible approach has wide application to pathogen surveillance and may be used to greatly accelerate diagnoses of resistant infections. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 17/251343 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246503 | Ludwig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leif S. Ludwig (Cambridge, Massachusetts); Caleb A. Lareau (Boston, Massachusetts); Jacob C. Ulirsch (Boston, Massachusetts); Aviv Regev (Cambridge, Massachusetts); Vijay G. Sankaran (Boston, Massachusetts); Jason Buenrostro (Cambridge, Massachusetts); Christoph Muus (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments disclosed herein provide methods of using somatic mutations in mitochondrial genomes to retrospectively infer cell lineages in native contexts and to serve as genetic barcodes to measure clonal dynamics in complex cellular populations. Further, somatic mutations in mitochondrial DNA (mtDNA) are tracked by single cell genomic approaches for simultaneous analysis of single cell lineage and state. Applicants further show that mitochondrial mutations can be readily detected with contemporary single cell transcriptomic and epigenomic technologies to concomitantly capture gene expression profiles and chromatin accessibility, respectively. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 17/251451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246509 | Weinand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin E. Weinand (Tucson, Arizona); Ryan Sprissler (Tucson, Arizona); Michael F. Hammer (Tucson, Arizona) |
| ABSTRACT | Methods involving analysis of pretreatment leukocyte expression profiles for prognostic assessment of seizure outcome following a treatment or medical procedure, such as stereotactic laser amygdalohippocampotomy (SLAH). In one aspect, RNA sequencing (RNA-Seq) on whole blood leukocyte samples is taken from a patient with intractable epilepsy prior to SLAH. Differential expression (DE) analysis revealed 24 significantly dysregulated genes (≥2.0-fold change, p-value<0.05, and False Discovery Rate, FDR<0.05) useful in prognostic assessment. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/269092 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246519 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Chiu (Oakland, California); Xianding Deng (Oakland, California) |
| ABSTRACT | Methods, compositions and kits for detection of a taxon of pathogenic microorganisms in a sample are provided. Also provided are methods, compositions and kits for detecting taxons of pathogenic microorganisms present in low titers in a sample. Compositions, methods and kits for detection of pathogenic co-infections are also provided. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 17/049320 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6895 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 25/20 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247331 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lei ZHU (Hefei, Anhui Province, China PRC); Michael Joseph PETRONGOLO, Jr. (Sewell, New Jersey) |
| ABSTRACT | Disclosed herein is a system and method, which utilize primary beam modulation to enable single-scan dual-energy CT (DECT) on a conventional CT scanner. An attenuation sheet with a spatially-varying pattern is placed between the x-ray source and the imaged object. During the CT scan, the modulator selectively hardens the x-ray beam at specific detector locations. Thus, this method simultaneously acquires high and low energy data at each projection angle. High and low energy CT images can then reconstructed from the projections via an iterative CT reconstruction algorithm, which accounts for the spatial modulation of the projected x-rays. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 16/310930 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/4035 (20130101) A61B 6/4078 (20130101) A61B 6/4085 (20130101) A61B 6/4208 (20130101) A61B 6/4435 (20130101) A61B 6/5229 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) Original (OR) Class G01N 23/083 (20130101) G01N 2223/424 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 2211/408 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247347 | Lindsay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stuart Lindsay (Scottsdale, Arizona); Joshua Sadar (Scottsdale, Arizona); Quan Qing (Scottsdale, Arizona) |
| ABSTRACT | The present disclosure provides devices, systems, and methods related to protein bioelectronics. In particular, the present disclosure provides bioelectronic devices, systems, and methods that utilize a defined electrical potential to maximize electrical conductance of a protein-of-interest, which can serve as a basis for the fabrication of enhanced bioelectronic devices for the direct measurement of protein activity. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173569 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/026 (20130101) G01N 27/3275 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247351 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XiuJun Li (El Paso, Texas); Wan Zhou (El Paso, Texas) |
| ABSTRACT | A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112841 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3276 (20130101) G01N 27/3277 (20130101) G01N 27/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247391 | STEERE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Allen C. STEERE (Wellesley, Massachusetts); Elise E. Drouin (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with P. copri or a portion thereof. In one aspect of the invention the immunological reactivity of the subject to one or more protein of P. copri or polypeptide fragments thereof such as protein Pc-p27 or polypeptide fragments thereof, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays, compositions, and kits for use with the methods are also disclosed. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116260 |
| CURRENT CPC | Peptides C07K 16/1257 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/564 (20130101) Original (OR) Class G01N 33/6878 (20130101) G01N 33/56916 (20130101) G01N 2469/20 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247406 | NEWMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Morehouse School of Medicine (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gale W. NEWMAN (Duluth, Georgia); James W. Lillard, JR. (Smyrna, Georgia); Chamberlain Obialo (Atlanta, Georgia) |
| ABSTRACT | The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244214 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/40 (20130101) A61K 31/422 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4025 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/78 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/56988 (20130101) G01N 2333/5754 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249102 | Hurwitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bonnie L. Hurwitz (Tucson, Arizona); George S. Watts (Tucson, Arizona); Illyoung Choi (Tucson, Arizona); John H. Hartman (Tucson, Arizona) |
| ABSTRACT | Systems and methods for metagenomic analysis are provided. A method of metagenome sequence analysis of two or more samples can include (i) counting the abundance of each k-mer deconstructed from sequencing reads of nucleic acids in each sample, and (ii) using a vector space model to compute the genetic distance between each of the two or more samples according to the abundance of the k-mers. In some embodiments, counting includes (a) constructing a k-mer histogram containing the distribution of k-mers for each sample, and (b) dividing k-mers into partitions having approximately an equal number of k-mers based on the histogram, preparing an inverted index of the k-mers in each partition, and assigning a weight to each k-mer according to its abundance. Method of developing diagnostic and prognostic information using the methods of sequence analysis are also provided. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 17/059993 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6223 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class G16B 40/00 (20190201) G16B 50/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250420 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Yingying Chen (Morganville, New Jersey); Jie Yang (Tallahassee, Florida); Yan Wang (Jersey City, New Jersey); Jian Liu (Jersey City, New Jersey); Marco Gruteser (Princeton, New Jersey) |
| ABSTRACT | A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219781 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/306 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/027 (20130101) H04W 4/029 (20180201) H04W 4/30 (20180201) H04W 88/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20210244022 | Veleva |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BENANOVA INC. (CARY, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anka Veleva (Cary, North Carolina) |
| ABSTRACT | Disclosed is a method for creating a composite colloidal particle formulation with advanced functionality that possesses highly efficient and effective properties. The composite colloidal particle formulation comprises an engineered biodegradable particle core dispersed in a bioadhesive polyelectrolyte solution. Also disclosed are methods of use of the same, including but not limited to applying said formulation to plants for disease treatment. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/247808 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/10 (20130101) A01N 25/22 (20130101) Original (OR) Class A01N 59/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245395 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Cai Wang (Tampa, Florida); YunJo Jeong (Tampa, Florida) |
| ABSTRACT | A method of forming a layered material including arranging a 2DLM on a base material comprising one or more Moiré interferences, and adding material or removing material at a location of the one or more Moiré interferences. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170103 |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/10 (20130101) B28B 11/0863 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 41/4505 (20130101) C04B 41/5001 (20130101) C04B 2235/945 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246031 | Hirschmugl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COnovate, Inc. (Shorewood, Wisconsin); University of Wisconsin-Milwaukee Research Foundation (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carol J. Hirschmugl (Shorewood, Wisconsin); Marija Gajdardziska-Josifovska (Fox Point, Wisconsin); Marvin Schofield (Milwaukee, Wisconsin); Yakov Kutsovsky (Arlington, Massachusetts); Xingkang Huang (Darien, Illinois) |
| ABSTRACT | A composition of graphene-based nanomaterials characterized by at least one area of one atomic layer of graphene monoxide, wherein at least a portion of oxygen molecules present in the graphene monoxide are incorporated into specific crystalline structural moieties, methods of making the same, electrodes in electrochemical devices incorporating the same, and compositions of lithium and graphene monoxide containing materials that result from cycling said electrodes. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/148010 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246045 | Chakrabarty et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rajan K. Chakrabarty (St. Louis, Missouri); Pai Liu (St. Louis, Missouri) |
| ABSTRACT | A process for gas-phase synthesis of titanium dioxide aerosol gels with controlled monomer size and crystalline phase using a diffusion flame aerosol reactor operated in a buoyancy-opposed configuration is disclosed. The process includes introducing a precursor stream into a diffusion flame aerosol reactor, introducing a fuel stream into the reactor, combusting the precursor stream and the fuel stream in a flame to form at least one nanoparticle, and operating the reactor in a down-fired buoyancy-opposed configuration to produce the aerosol gel. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 16/341825 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0095 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/07 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/50 (20130101) C01P 2004/61 (20130101) C01P 2004/64 (20130101) C01P 2006/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246266 | Alim et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marvin D. Alim (Kirkland, Washington); Christopher N. Bowman (Boulder, Colorado); Sudheendran Mavila (Boulder, Colorado); Robert R. McLeod (Boulder, Colorado) |
| ABSTRACT | The present invention, in one aspect, relates to monomers and photopolymers that exhibit a high refractive index. The photopolymers of the invention have properties suitable for fabricating holographic optical elements (HOEs). |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/972884 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/50 (20130101) C08F 20/38 (20130101) C08F 28/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/02 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/004 (20130101) Holographic Processes or Apparatus G03H 1/024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246412 | Burge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Burge Environmental, Inc. (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott R. Burge (Tempe, Arizona); David A. Hoffman (Tempe, Arizona) |
| ABSTRACT | A microbial sensor, system and method that can be used to determine the chemical environment and/or substrate concentrations in saturated and unsaturated natural and environments, such as soils, aquifers and sediments are disclosed. The system may be used for monitoring municipal and industrial treatment facilities and sites where chemicals or contaminants were released to natural environments. The electrochemical microbial sensor system can be referenced using either a cathode exposed to oxygen or a reference cell (silver/silver chloride or calomel) for monitoring natural or man-made environments. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244440 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/32 (20130101) C12M 41/46 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/404 (20130101) G01N 27/411 (20130101) G01N 27/4035 (20130101) G01N 33/24 (20130101) G01N 33/1806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246455 | DE ABREU RIBEIRO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cairn Biosciences, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M. Susana G. DE ABREU RIBEIRO (San Francisco, California); Catherine I. LACAYO (Fremont, California); Mary J. C. LUDLAM (San Francisco, California) |
| ABSTRACT | The present invention provides assays for profiling two or more polypeptides in live cells. In some embodiments, the invention provides multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells. Methods of making multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Libraries and kits comprising multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Methods of profiling/assaying the multireporter cells and multireporter cell libraries are provided. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/614297 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 15/1093 (20130101) C12N 2830/20 (20130101) C12N 2840/002 (20130101) C12N 2840/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246569 | Markovski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jasmina Markovski (Mesa, Arizona); Aliaksandr Sharstniou (Gilbert, Arizona); Stanislau Niauzorau (Gilbert, Arizona); Bruno Azeredo (Scottsdale, Arizona); Yifu Ding (Superior, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jasmina Markovski (Mesa, Arizona); Aliaksandr Sharstniou (Gilbert, Arizona); Stanislau Niauzorau (Gilbert, Arizona); Bruno Azeredo (Scottsdale, Arizona); Yifu Ding (Superior, Colorado) |
| ABSTRACT | A metal-assisted chemical imprinting stamp includes a porous polymer substrate and a noble metal coating formed directly on the porous polymer substrate. Fabricating the metal-assisted chemical imprinting stamp includes providing a porous polymer substrate, and disposing a noble metal on the porous polymer substrate. Metal-assisted chemical imprinting includes positioning a silicon substrate in an etching solution, contacting a surface of the silicon substrate with a stamp comprising a noble metal layer on a surface of a porous polymer substrate, and separating the silicon substrate from the stamp to yield a pattern corresponding to the noble metal layer on the silicon substrate. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173837 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/205 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/12 (20130101) Original (OR) Class C25F 3/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247180 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Qiaoen Luo (West Lafayette, Indiana); Justin A. Patel (West Lafayette, Indiana); Kevin J. Webb (West Lafayette, Indiana) |
| ABSTRACT | An ultra-sensitive speckle-analyzing system is disclosed which includes an image capture device configured to receive a scattered field having a speckle configuration and thereby capture i) a reference speckle image, and ii) a subsequent speckle image, each of the reference and the subsequent speckle images having a plurality of speckles on a background; and a processor configured to generate a cross-correlation between the plurality of speckles of the reference and the subsequent speckle images, to thereby represent a change in the speckle configuration. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150880 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247239 | Qoutb et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdelrahman G. Qoutb (Rochester, New York); Eby G. Friedman (Rochester, New York) |
| ABSTRACT | A hybrid integrated thermal sensor device includes a magnetic tunnel junction (MTJ) device electrically coupled in series with at least one CMOS transistor and disposed between a voltage rail terminal and a ground terminal. An output terminal is electrically coupled to a drain of the at least one CMOS transistor. The MTJ operates in an anti-parallel state and the output terminal provides a voltage indicative of a temperature of the MTJ device based on an MTJ antiparallel resistance. A distributed sensor network for real-time thermal mapping of an integrated circuit (IC) is also described. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/787681 |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/026 (20130101) G01K 3/005 (20130101) G01K 7/01 (20130101) Original (OR) Class G01K 13/00 (20130101) G01K 2213/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247285 | Fini et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Daniel Oldham (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Daniel Oldham (Tempe, Arizona) |
| ABSTRACT | Assessing an interaction between solid particles and a thermoplastic material in which the solid particles are dispersed includes combining a thermoplastic material with a multiplicity of solid particles to yield a heterogeneous mixture, processing the heterogeneous mixture to yield an unconditioned sample, conditioning the unconditioned sample to yield a conditioned sample, subjecting the conditioned sample to a ramping shear rate from an initial shear rate to a final shear rate, assessing a viscosity of the conditioned sample at a plurality of shear rates between the initial shear rate and the final shear rate, and assessing a value of a slope of a shear-thinning region for the unconditioned sample using a power-law equation. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169080 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247351 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XiuJun Li (El Paso, Texas); Wan Zhou (El Paso, Texas) |
| ABSTRACT | A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112841 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3276 (20130101) G01N 27/3277 (20130101) G01N 27/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247375 | Toreyin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
| ASSIGNEE(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
| INVENTOR(S) | Hakan Toreyin (San Diego, California) |
| ABSTRACT | A system and method for detecting, amplifying, and sorting non-transitory signals stemming from cellular activity of tissue in an extracellular medium is presented herein. Weak signals are difficult to detect, especially when they originate far from the measuring electrode. The invention takes advantage of stochastic resonance, i.e. adding noise to signals to amplify them and make them more detectable, to improve signal detection from a single electrode. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/128224 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4836 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0051 (20130101) G06K 9/0055 (20130101) G06K 9/0057 (20130101) G06K 9/00523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247390 | VEMULAPATI et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Sasank VEMULAPATI (Ithaca, New York); David ERICKSON (Ithaca, New York) |
| ABSTRACT | The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets mounted on the surface or in the wall of the magnetic separation chamber. The device also includes a force provider configured to move the magnetic separation chamber in a side-to-side motion to mix and/or magnetize the fluid sample. In one embodiment, the magnetic separation chamber is in a form of a sleeve and comprises a substantially central channel for loading a vessel containing the fluid sample therein. The systems and methods of the present disclosure involve the use of this device to separate biological entities from fluid samples. |
| FILED | Monday, July 22, 2019 |
| APPL NO | 17/261855 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 33/54326 (20130101) Original (OR) Class G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247797 | Gu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jie Gu (Evanston, Illinois); Tianyu Jia (Binzhou, China PRC) |
| ABSTRACT | A system for clock management in an m columns×n rows array-based accelerators. Each row of the array may include a clock domain that clocks runtime clock cycles for the m processing elements. The clock domain includes a data detection and timing control circuit which is coupled to a common clock phase bus which provides a local clock source in multiple selectable phases, wherein the data detection and timing control circuit is configured to select a clock phase to clock a next clock cycle for a next concurrent data processing by the m processing elements. Each of m processing elements is coupled to access data from a first memory and a second memory and to generate respective outputs from each of the m processing elements to a corresponding m processing element of a same column in a subsequent neighboring row for the next processing in the next clock cycle. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170187 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/08 (20130101) Original (OR) Class G06F 1/12 (20130101) G06F 9/5027 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247839 | Pathak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Divya Pathak (Bengaluru, Karnataka, India); Ioannis Savidis (Wallingford, Pennsylvania) |
| ABSTRACT | An on-chip voltage delivery method for a system includes multiple processor cores operating at multiple voltage levels. Distributed on-chip DC-DC converters as voltage regulators may deliver point of load current to the different units of a processor core operating at the same voltage level. Distributed timing sensors calibrated to generate digitized clock edge location. A power management unit may take input from the timing sensors, processes it through a particle swarm optimizer and generates digitized voltage identification code as reference to the distributed voltage regulators. The particle swarm optimizer may provide disparate voltage levels feasible for a given frequency of operation of the processor core with a provision to operate at multiple frequencies. The run-time assignment of the voltage through the particle swarm optimizer may negate the effects of transistor aging, process, temperature, and power supply noise induced variation in the load circuits, voltage regulators and sensors. |
| FILED | Tuesday, September 03, 2019 |
| APPL NO | 17/271121 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/324 (20130101) G06F 1/3243 (20130101) G06F 1/3296 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/006 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210248335 | STANACEVIC et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Milutin STANACEVIC (Smithtown, New York); Samir DAS (Melville, New York); Djuric PETAR (Setauket, New York); Athalye AKSHAY (Forest Hills, New York); Ryoo JIHOON (Incheon, South Korea); Karimi YASHA (Selden, New York) |
| ABSTRACT | A method, system and apparatus are provided for estimating characteristics of a wireless communication channel between at least two passive radio frequency (RF) nodes. Backscatter channel state information (BCSI) is measured during communication between the at least two passive RF nodes using the wireless communication channel. An RF node aggregates the measured BCSI and the aggregated BSCI is analyzed to detect at least one activity of a plurality of activities. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/972829 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Original (OR) Class G06K 19/0723 (20130101) G06K 19/07773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210248480 | Hill et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Hill (La Jolla, California); Sheldon Brown (La Jolla, California); Wesley Hawkins (La Jolla, California) |
| ABSTRACT | A data analysis and processing method includes forming an initial assembly of datasets comprising multiple entities, where each entity is a collection of variables and relationships that define how entities interact with each other, simulating an evolution of the initial assembly by performing multiple iterations in which a first iteration uses the initial assembly as a starting assembly, and querying, during the simulating, the evolution of the initial assembly, for datasets that meet an optimality criterion. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 17/260993 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/69 (20140902) Electric Digital Data Processing G06F 9/455 (20130101) G06F 16/245 (20190101) Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210248516 | Woodbury |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neal Woodbury (Tempe, Arizona) |
| ABSTRACT | Methods and systems, including those employing machine learning, utilizing one or more algorithms for relating the structure of a molecule in a library to its function are described. Embodiments described herein relate structure to function by considering the covalent structure of the molecule, the components of that structure that are common to many molecules in the library, and the properties of those components as they relate to the function in question. Applications include, for example, enhancement and amplification of the diagnostic and prognostic signals provided by peptide arrays for use in analyzing the profile of antibodies in the blood produced in response to a disease, condition or treatment. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/637369 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/10 (20190101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249102 | Hurwitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bonnie L. Hurwitz (Tucson, Arizona); George S. Watts (Tucson, Arizona); Illyoung Choi (Tucson, Arizona); John H. Hartman (Tucson, Arizona) |
| ABSTRACT | Systems and methods for metagenomic analysis are provided. A method of metagenome sequence analysis of two or more samples can include (i) counting the abundance of each k-mer deconstructed from sequencing reads of nucleic acids in each sample, and (ii) using a vector space model to compute the genetic distance between each of the two or more samples according to the abundance of the k-mers. In some embodiments, counting includes (a) constructing a k-mer histogram containing the distribution of k-mers for each sample, and (b) dividing k-mers into partitions having approximately an equal number of k-mers based on the histogram, preparing an inverted index of the k-mers in each partition, and assigning a weight to each k-mer according to its abundance. Method of developing diagnostic and prognostic information using the methods of sequence analysis are also provided. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 17/059993 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6223 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class G16B 40/00 (20190201) G16B 50/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249513 | Chaudhuri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Reet Chaudhuri (Ithaca, New York); Samuel James Bader (Hillsboro, Oregon); Jena Debdeep (Ithaca, New York); Huili Grace Xing (Ithaca, New York) |
| ABSTRACT | The long-missing polarization-induced two-dimensional hole gas is finally observed in undoped Group III nitride semiconductor structures and in undoped Group II or Group III oxide semiconductor structures. Experimental results providing unambiguous proof that a 2D hole gas in GaN grown on AlN does not need acceptor doping, and can be formed entirely by the difference in the internal polarization fields across the semiconductor heterojunction are presented. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 17/261309 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/04 (20130101) H01L 29/267 (20130101) Original (OR) Class H01L 29/7786 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249862 | Awal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M A. Awal (Raleigh, North Carolina); Iqbal Husain (Raleigh, North Carolina) |
| ABSTRACT | A power electronic converter can utilize exemplary double synchronous unified virtual oscillator control (DSUVOC) logic or circuitry to convert direct current to alternating current that is input into a power grid. An exemplary DSUVOC controller of the present disclosure includes a double synchronous space vector oscillator component, a sequence extraction component, a fault detection component, a pre-synchronization component, a virtual impedance component, a terminal voltage compensation component, and/or an active damping component, wherein the double synchronous unified virtual oscillator controller is capable of controlling a grid following or a grid forming power electronic converter enabling synchronization and fault ride-through under both balanced and unbalanced conditions. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173505 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/0012 (20200101) H02J 3/24 (20130101) Original (OR) Class Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250025 | Johnson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nonvologic LLC (Meredith, New Hampshire) |
| ASSIGNEE(S) | Nonvologic LLC (Meredith, New Hampshire) |
| INVENTOR(S) | Mark B. Johnson (Potomac, Maryland) |
| ABSTRACT | An electronic environmental sensor tag includes microsensor elements using magnetic logic devices adapted to detect target chemical and/or target environmental conditions. The microsensor elements operate only periodically to save power, and also include non-volatile memories and communications circuits to allow interrogation and detection of a target condition. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/156918 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 27/122 (20130101) G01N 27/127 (20130101) G01N 27/128 (20130101) Pulse Technique H03K 19/017581 (20130101) Original (OR) Class Transmission H04B 1/40 (20130101) H04B 5/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250420 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Yingying Chen (Morganville, New Jersey); Jie Yang (Tallahassee, Florida); Yan Wang (Jersey City, New Jersey); Jian Liu (Jersey City, New Jersey); Marco Gruteser (Princeton, New Jersey) |
| ABSTRACT | A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219781 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/306 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/027 (20130101) H04W 4/029 (20180201) H04W 4/30 (20180201) H04W 88/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20210244439 | Frederick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Frederick (Gretna, Nebraska); Shane Farritor (Lincoln, Nebraska); Jack Mondry (Edina, Minnesota); Eric Markvicka (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska); Jacob Greenburg (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning surgical systems or devices into the cavity. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999407 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0218 (20130101) A61B 17/3423 (20130101) Original (OR) Class A61B 17/3498 (20130101) A61B 90/40 (20160201) A61B 2017/3447 (20130101) A61B 2034/302 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244686 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuedong Liu (Niwot, Colorado); Douglas Chapnick (Boulder, Colorado); William Old (Boulder, Colorado) |
| ABSTRACT | The invention includes the use of cannabidiol (CBD), and cannabidiol analogs, as therapeutic compounds or formulations for the increase of lipid order in the cell membranes of a patient. This increase in membrane lipid order may cause downstream therapeutic effects that may ameliorate certain disease conditions such as cardio vascular disease, high-cholesterol and Alzheimer's disease. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 17/255214 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/09 (20130101) A61K 31/13 (20130101) A61K 31/27 (20130101) A61K 31/55 (20130101) A61K 31/192 (20130101) A61K 31/352 (20130101) A61K 31/445 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244799 | Gan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rong Z. Gan (Oklahoma City, Oklahoma); Tao Chen (Chongqing, China PRC) |
| ABSTRACT | Methods of treating a subject for hearing loss or auditory impairment or damage, such as blast-induced hearing damage, comprising administering to the subject in need of such treatment an effective quantity of a glucagon-like peptide-1 receptor (GLP-1R) agonist. The treatment may be given after exposure to a blast, loud noise, or other hearing loss-inducing traumatic event, or may be prophylactic, i.e., given prior to exposure to a blast or loud noise. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231381 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244802 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Daniel C. Nelson (Rockville, Maryland); Irina V. Etobayeva (Kensington, Maryland) |
| ABSTRACT | The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces, including an isolated polypeptide comprising an enzymatically active domain (EAD) of a Bacillus bacteriophage endolysin. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/054539 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) Original (OR) Class A61K 38/162 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244850 | Bellas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evangelia Bellas (Philadelphia, Pennsylvania); Kacey Marra (Canonsburg, Pennsylvania); J. Peter Rubin (Pittsburgh, Pennsylvania); David L. Kaplan (Concord, Massachusetts); James J. Yoo (Winston-Salem, North Carolina) |
| ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection) and/or be molded flexibly into a tissue void of any shape and/or size. In some embodiments, the composition described herein comprises a plurality of silk fibroin particles, which can retain their original volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091835 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244854 | Biris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandru S. Biris (Little Rock, Arkansas); Karrer M. Alghazali (Little Rock, Arkansas); Anwer Dheyaa Mahdi Mhannawee (Little Rock, Arkansas) |
| ABSTRACT | The disclosure relates to an expandable scaffold and a method for fabricating the scaffold. The expandable scaffold includes a three-dimensional porous structure comprising a composite material composed by a first material and a second material. The 3D porous structure has a tunable expansion capacity. When applied in a liquid, the 3D porous structure may uptake the liquid and expand from an original volume to an expansion volume up to 1000 times of the original volume. The 3D porous structure may be formed by a plurality of layers of the composite material, and architecture and shape of the layers of the composite material are arranged in accordance with a shape and a size of the expansion volume. Applications of the scaffold may include a bone or soft tissue regeneration system or a bleed stopping device. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783256 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/08 (20130101) A61L 27/12 (20130101) A61L 27/20 (20130101) A61L 27/24 (20130101) A61L 27/38 (20130101) A61L 27/56 (20130101) A61L 27/365 (20130101) Original (OR) Class A61L 27/3695 (20130101) A61L 2400/04 (20130101) A61L 2400/06 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244989 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Linda S. Lee (West Lafayette, Indiana); Jenny E. Zenobio (Arlington, Massachusetts) |
| ABSTRACT | The present application relates to a novel method for reductive degradation of perfluoroalkyl-containing compounds, such as perfluoroalkyl sulfonates, by activated carbon (AC) supported zero valent iron-nickle nanoparticles (nNi0Fe0). |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244219 |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/34 (20130101) Original (OR) Class A62D 3/37 (20130101) A62D 2101/22 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/755 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) C02F 1/705 (20130101) C02F 2101/36 (20130101) C02F 2103/06 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245491 | McIver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Carl R. McIver (Everett, Washington); Brice A. Johnson (Federal Way, Washington); Michael R. Anderson (Renton, Washington) |
| ABSTRACT | An apparatus is provided for peeling a liner away from a substrate. The apparatus comprises a first member rotatable about an axis. The apparatus also comprises a second member disposed on the first member and for generating a suction force to be applied to the liner to peel a portion of the liner away from the substrate when the suction force of the second member is applied to the liner and the first member is rotating about its axis. The apparatus further comprises a third member synchronized to rotation of the first member about its axis such that the third member clamps the peeled portion of the liner against the first member while the second member is applying suction force to the liner and the first member is rotating about its axis. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784732 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 43/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246030 | Amiri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Ahmad Amiri (College Station, Texas); Mohammad Naraghi (Cypress, Texas) |
| ABSTRACT | A method for manufacturing graphene-based materials includes (a) positioning graphite into an inner chamber of a rotatable housing of a rod mill. A plurality of elongate rigid rods are loosely positioned in the housing. In addition, the method includes (b) rotating the housing of the rod-mill after (a). Further, the method includes (c) rod milling the graphite with the rods during (b) to produce a first portion of the graphene-based materials and milled graphite. The first portion of the graphene-based materials include 30 layers or less of graphene and the milled graphite comprises more than 30 layers of graphene. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/973378 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Original (OR) Class C01B 32/194 (20170801) C01B 2204/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246066 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vinh Q. Nguyen (Fairfax, Virginia); Mikhail Kotov (Silver Spring, Maryland); Daniel J. Gibson (Falls Church, Virginia); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Gryphon A. Drake (Potomac, Maryland) |
| ABSTRACT | The present invention provides for synthesizing high optical quality multicomponent chalcogenide glasses without refractive index perturbations due to striae, phase separation or crystal formation using a two-zone furnace and multiple fining steps. The top and bottom zones are initially heated to the same temperature, and then a temperature gradient is created between the top zone and the bottom zone. The fining and cooling phase is divided into multiple steps with multiple temperature holds. |
| FILED | Tuesday, April 27, 2021 |
| APPL NO | 17/241378 |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 1/00 (20130101) C03B 5/06 (20130101) C03B 5/16 (20130101) C03B 5/187 (20130101) C03B 25/00 (20130101) C03B 27/028 (20130101) C03B 2201/86 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246437 | SIEGEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Bloomfield SIEGEL (Seattle, Washington); David BAKER (Seattle, Washington); Ingrid Swanson PULTZ (Seattle, Washington) |
| ABSTRACT | The invention provides compositions and methods for treating celiac sprue. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230230 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class C12N 9/64 (20130101) C12N 9/6489 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246452 | YAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENT ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hao YAN (Chandler, Arizona); Yung CHANG (Tempe, Arizona); Xiaowei LIU (Tempe, Arizona); Fei ZHANG (Chandler, Arizona); Xiaodong QI (Tempe, Arizona) |
| ABSTRACT | Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory). |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/642792 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) Original (OR) Class C12N 2310/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246850 | Cicchini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nicholas P. Cicchini (Vail, Arizona) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Nicholas P. Cicchini (Vail, Arizona) |
| ABSTRACT | A method of reducing low-energy flow in a flight vehicle engine includes an isolator of the engine having a swept-back wedge to improve flow mixing. The wedge includes forward shock-anchoring locations, such as edges or rapidly-curved portions, that anchor oblique shocks in situations where the isolator has sufficient back pressure. The swept-back wedge may also create swept oblique shocks along its length. Boundary layer flow streamlines are diverted running parallel to or parallel but moving outward conically to the swept-wedge leading edge moving outboard and upward. The non-viscous flow outside the boundary layer is processed through the swept-back ramp shock and diverted outboard and upward as well. The outboard aft portion of the wedge at the sidewall intersection may also induce shocks and divert flow near the walls closer toward the walls and upward, and/or improve flow mixing. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242394 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 23/04 (20130101) B64C 30/00 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/20 (20130101) B64D 33/02 (20130101) B64D 2033/026 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/04 (20130101) Jet-propulsion Plants F02K 7/00 (20130101) F02K 7/08 (20130101) F02K 7/10 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/10 (20130101) F05D 2250/51 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/38 (20130101) F42B 10/42 (20130101) F42B 15/10 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210248443 | Shu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaokui Shu (Ossining, New York); Zhongshu Gu (Ridgewood, New Jersey); Marc P. Stoecklin (Richterswil, Switzerland); Hani T. Jamjoom (Cos Cob, Connecticut) |
| ABSTRACT | Mechanisms for identifying a pattern of computing resource activity of interest, in activity data characterizing activities of computer system elements, are provided. A temporal graph of the activity data is generated and a filter is applied to the temporal graph to generate one or more first vector representations, each characterizing nodes and edges within a moving window defined by the filter. The filter is applied to a pattern graph representing a pattern of entities and events indicative of the pattern of interest, to generate a second vector representation. The second vector representation is compared to the one or more first vector representations to identify one or more nearby vectors, and one or more corresponding subgraph instances are output to an intelligence console computing system as inexact matches of the temporal graph. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783274 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9017 (20190101) G06F 16/9024 (20190101) G06F 16/9035 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6296 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/0436 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249331 | Ueda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Ueda (Whittier, California); Aaron McLeod (La Jolla, California); Andrew Kummel (San Diego, California); Mike Burkland (Tucson, Arizona); Eduardo M. Chumbes (Andover, Massachusetts); Thomas E. Kazior (Arlington, Virginia); Eric Pop (Stanford, California); Michelle Chen (Stanford, California); Chris Perez (Stanford, California); Mark Rodwell (Santa Barbara, California) |
| ABSTRACT | Provided are high quality metal-nitride, such as aluminum nitride (AlN), films for heat dissipation and heat spreading applications, methods of preparing the same, and deposition of high thermal conductivity heat spreading layers for use in RF devices such as power amplifiers, high electron mobility transistors, etc. Aspects of the inventive concept can be used to enable heterogeneously integrated compound semiconductor on silicon devices or can be used in in non-RF applications as the power densities of these highly scaled microelectronic devices continues to increase. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/169914 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4807 (20130101) H01L 23/3731 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249468 | Heron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Thomas Heron (Saline, Michigan); Peter Benjamin Meisenheimer (Ann Arbor, Michigan); Darrell G. Schlom (Ithaca, New York); Rachel Steinhardt (Brooktondale, New York) |
| ABSTRACT | A heterostructure includes a substrate exhibiting a piezoelectric effect, and a magnetostrictive film supported by the substrate. The magnetostrictive film includes an iron-gallium alloy. The iron-gallium alloy has a gallium composition greater than 20%. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784351 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) Original (OR) Class H01L 41/20 (20130101) H01L 41/47 (20130101) H01L 41/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249513 | Chaudhuri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Reet Chaudhuri (Ithaca, New York); Samuel James Bader (Hillsboro, Oregon); Jena Debdeep (Ithaca, New York); Huili Grace Xing (Ithaca, New York) |
| ABSTRACT | The long-missing polarization-induced two-dimensional hole gas is finally observed in undoped Group III nitride semiconductor structures and in undoped Group II or Group III oxide semiconductor structures. Experimental results providing unambiguous proof that a 2D hole gas in GaN grown on AlN does not need acceptor doping, and can be formed entirely by the difference in the internal polarization fields across the semiconductor heterojunction are presented. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 17/261309 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/04 (20130101) H01L 29/267 (20130101) Original (OR) Class H01L 29/7786 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250025 | Johnson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nonvologic LLC (Meredith, New Hampshire) |
| ASSIGNEE(S) | Nonvologic LLC (Meredith, New Hampshire) |
| INVENTOR(S) | Mark B. Johnson (Potomac, Maryland) |
| ABSTRACT | An electronic environmental sensor tag includes microsensor elements using magnetic logic devices adapted to detect target chemical and/or target environmental conditions. The microsensor elements operate only periodically to save power, and also include non-volatile memories and communications circuits to allow interrogation and detection of a target condition. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/156918 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 27/122 (20130101) G01N 27/127 (20130101) G01N 27/128 (20130101) Pulse Technique H03K 19/017581 (20130101) Original (OR) Class Transmission H04B 1/40 (20130101) H04B 5/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250049 | Gabrys et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Christopher Gabrys (San Diego, California); Jayson T. Durham (San Diego, California) |
| ABSTRACT | At a physical data-link in a network, a current status of a plurality of logical data-channels in the network is determined, using machine learning to infer the current status. A plurality of cross-layer error correction coding schemes for transmissions is adaptively adjusted, based on the determined current status, and based on an application transmitting data. Transmission of the data, and a plurality of information-exchange requirements, are supported, using the adaptively adjusted plurality of error correction coding schemes. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/788051 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Coding; Decoding; Code Conversion in General H03M 13/1515 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0061 (20130101) H04L 25/024 (20130101) H04L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250536 | Collins, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Thomas E. Collins, III (Tyngsboro, Massachusetts); Dimitre P. Dimitrov (Wayland, Massachusetts); Allen W. Hairston (Andover, Massachusetts) |
| ABSTRACT | Techniques, systems, architectures, and methods for reducing peak power during an Analog-to-Digital Conversion (ADC) process, in embodiments on a Focal Plane Array (FPA). |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/787741 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/34 (20130101) H03M 1/56 (20130101) Pictorial Communication, e.g Television H04N 5/378 (20130101) Original (OR) Class H04N 5/3765 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20210244751 | GRDINA |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | David J. GRDINA (Naperville, Illinois) |
| ABSTRACT | Described are methods for preventing or inhibiting genomic instability and in cells affected by diagnostic radiology procedures employing ionizing radiation. Embodiments include methods of preventing or inhibiting genomic instability and in cells affected by computed tomography (CT) radiation. Subjects receiving ionizing radiation may be those persons suspected of having cancer, or cancer patients having received or currently receiving cancer therapy, and or those patients having received previous ionizing radiation, including those who are approaching or have exceeded the recommended total radiation dose for a person. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/302143 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/508 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/132 (20130101) A61K 31/145 (20130101) A61K 31/355 (20130101) A61K 31/661 (20130101) Original (OR) Class A61K 33/04 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245112 | Stewart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); UChicago Argonne, LLC (Chicago, Illinois); Adamas Nanotechnologies, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederick F. Stewart (Idaho Falls, Idaho); Christopher J. Orme (Firth, Idaho); John R. Klaehn (Idaho Falls, Idaho); Birendra Adhikari (Ammon, Idaho); Olga Aleksandrovna Shenderova (Raleigh, North Carolina); Nicholas Austin Nunn (Garner, North Carolina); Marco D. Torelli (Raleigh, North Carolina); Gary Elder McGuire (Chapel Hill, North Carolina); Tae H. Lee (Naperville, Illinois); Uthamalingam Balachandran (Willowbrook, Illinois) |
| ABSTRACT | A mixed matrix membrane comprises a support structure. The support structure comprises a glassy polymer matrix, and nanodiamond particles dispersed within the glassy polymer matrix. A gas separation membrane apparatus, a gaseous fluid treatment system, and a method of forming a mixed matrix membrane are also described. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/174796 |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 67/0079 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/021 (20130101) B01D 71/38 (20130101) B01D 71/68 (20130101) B01D 71/82 (20130101) B01D 2256/12 (20130101) B01D 2257/102 (20130101) B01D 2317/025 (20130101) B01D 2323/36 (20130101) B01D 2325/12 (20130101) B01D 2325/20 (20130101) B01D 2325/22 (20130101) B01D 2325/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245139 | SEABAUGH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEXCERIS INNOVATION HOLDINGS, LLC. (Lewis Center, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew SEABAUGH (Columbus, Ohio); Naftali OPEMBE (Powell, Ohio); Douglas MITCHELL (Monrovia, Indiana) |
| ABSTRACT | A catalyst having a core comprising a composite (A) of SiC grains and a protective matrix of one or more metal oxides, such as alumina, in voids between the SiC grains, said core having a density >60% of theoretical density, and a catalytically active layer (C) containing, e.g., Ni adhered to the core. A catalyst support comprising a composite of SiC grains and a protective matrix of one or more metal oxides in voids between the SiC grains is also provided, along with a method of fabricating a catalyst core. The catalyst can be used in Fischer-TRopsch synthesis or in steam methane reforming. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/972865 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 21/12 (20130101) Original (OR) Class B01J 23/755 (20130101) B01J 27/224 (20130101) B01J 33/00 (20130101) B01J 35/0006 (20130101) B01J 35/008 (20130101) B01J 35/026 (20130101) B01J 37/04 (20130101) B01J 37/0018 (20130101) B01J 37/082 (20130101) B01J 37/0207 (20130101) B01J 37/0217 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 2203/107 (20130101) C01B 2203/0233 (20130101) C01B 2203/1047 (20130101) C01B 2203/1052 (20130101) C01B 2203/1058 (20130101) C01B 2203/1064 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/332 (20130101) C10G 2/333 (20130101) C10G 2300/70 (20130101) C10G 2300/1022 (20130101) C10G 2300/4006 (20130101) C10G 2300/4012 (20130101) C10G 2300/4018 (20130101) C10G 2400/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245182 | Fedorov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrei G. Fedorov (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure provide for methods and systems for making structures using an electrospray system while under vacuum. In particular, embodiments of the present disclosure provide for methods and systems for ultra-fast growth of high aspect ratio nano/meso/micro-structures with three dimensional topological complexity and control of phase and composition of the structure formed. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/223620 |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/16 (20130101) Original (OR) Class B05B 5/035 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 3/068 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/145 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245246 | Lara-Curzio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edgar Lara-Curzio (Oak Ridge, Tennessee); Corson L. Cramer (Oak Ridge, Tennessee); Amelia M. Elliott (Oak Ridge, Tennessee); Brian A. Fricke (Oak Ridge, Tennessee); Prashant K. Jain (Oak Ridge, Tennessee); Richard R. Lowden (Oak Ridge, Tennessee); Kashif Nawaz (Oak Ridge, Tennessee); Vivek M. Rao (Oak Ridge, Tennessee); Matthew J. Sandlin (Oak Ridge, Tennessee) |
| ABSTRACT | A method for fabricating heat exchangers using additive manufacturing technologies. Additive manufacturing enables the manufacture of heat exchangers with complex geometries and/or with internal and external integral surface features. Additive manufacture also facilitates the manufacture of heat exchangers with regional variations, such as changes in size, shape and surface features. In one embodiment, the present invention provides a heat exchanger with a helicoidal shape that provides axial elastic compliance. In one embodiment, the internal channel of the heat exchanger varies along its length. The internal channel may have a cross-sectional area that increases progressively from one end to the other. In one embodiment, the external shape of the tubular structure may be non-circular to optimize heat transfer with an external heat transfer fluid. In one embodiment, the present invention provides a heat pipe with an internal wicking structure formed as an integral part of the additive manufacturing process. |
| FILED | Tuesday, February 09, 2021 |
| APPL NO | 17/171323 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 5/10 (20130101) B22F 10/20 (20210101) Original (OR) Class B22F 2998/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) F28D 15/0233 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2255/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210245296 | YE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianchao YE (Tracy, California); John ROEHLING (Livermore, California); Jae Hyuck YOO (Dublin, California) |
| ABSTRACT | The present disclosure relates to a system for laser processing of a ceramic electrolyte material. The system may include a controller, a laser responsive to the controller for generating a beam, and a beam forming subsystem. The beam forming subsystem controls a parameter of the beam generated by the laser. The beam forming subsystem further controls the beam to provide a laser fluence sufficient to produce densification of the ceramic electrolyte material. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783910 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0622 (20151001) Original (OR) Class B23K 2103/52 (20180801) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246031 | Hirschmugl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COnovate, Inc. (Shorewood, Wisconsin); University of Wisconsin-Milwaukee Research Foundation (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carol J. Hirschmugl (Shorewood, Wisconsin); Marija Gajdardziska-Josifovska (Fox Point, Wisconsin); Marvin Schofield (Milwaukee, Wisconsin); Yakov Kutsovsky (Arlington, Massachusetts); Xingkang Huang (Darien, Illinois) |
| ABSTRACT | A composition of graphene-based nanomaterials characterized by at least one area of one atomic layer of graphene monoxide, wherein at least a portion of oxygen molecules present in the graphene monoxide are incorporated into specific crystalline structural moieties, methods of making the same, electrodes in electrochemical devices incorporating the same, and compositions of lithium and graphene monoxide containing materials that result from cycling said electrodes. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/148010 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246032 | Loeb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Colin Loeb (Fairfield, California); Patrick Campbell (Oakland, California); Jennifer Marie Knipe (Oakland, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | A product includes an aerogel having a single bulk structure, the single bulk structure having at least one dimension greater than 10 millimeters. The single bulk structure includes a plurality of pores, where each pore has a largest diameter defined as a greatest distance between pore walls of the respective pore. In addition, an average of the largest diameters of a majority of the pores is within a specified range, and the plurality of pores are distributed substantially homogenously throughout the single bulk structure. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784385 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/318 (20170801) Original (OR) Class C01B 32/336 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 8/22 (20130101) C08G 2101/0091 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/36 (20130101) C08J 9/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246063 | Gangloff, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John J. Gangloff, JR. (Middletown, Connecticut); Paul Sheedy (Bolton, Connecticut); Rajiv Ranjan (South Windsor, Connecticut) |
| ABSTRACT | A method of fabricating a glass matrix composite includes providing a fiber preform in a cavity of a die tooling, the fiber preform circumscribing an interior region; providing a parison of glass matrix material in the interior region, the glass matrix material having a first viscosity; introducing pressurized inert gas into the parison to outwardly inflate the parison against the fiber preform; and while under pressure from the pressurized inert gas, decreasing the first viscosity of the glass matrix material to a second viscosity. The pressure and the second viscosity cause the glass matrix material to flow and infiltrate into the fiber preform to thereby form a consolidated workpiece. The consolidated workpiece is then cooled to form a glass matrix composite. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784384 |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 9/347 (20130101) Original (OR) Class Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 10/00 (20130101) C03C 14/002 (20130101) C03C 2214/20 (20130101) C03C 2214/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246412 | Burge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Burge Environmental, Inc. (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott R. Burge (Tempe, Arizona); David A. Hoffman (Tempe, Arizona) |
| ABSTRACT | A microbial sensor, system and method that can be used to determine the chemical environment and/or substrate concentrations in saturated and unsaturated natural and environments, such as soils, aquifers and sediments are disclosed. The system may be used for monitoring municipal and industrial treatment facilities and sites where chemicals or contaminants were released to natural environments. The electrochemical microbial sensor system can be referenced using either a cathode exposed to oxygen or a reference cell (silver/silver chloride or calomel) for monitoring natural or man-made environments. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244440 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/32 (20130101) C12M 41/46 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/404 (20130101) G01N 27/411 (20130101) G01N 27/4035 (20130101) G01N 33/24 (20130101) G01N 33/1806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246551 | Otto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Laminera LLC (Berkeley, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lauren M. Otto (Berkeley, California); Adam M. Schwartzberg (Richmond, California); Shaul Aloni (El Cerrito, California); Edward K. S. Wong (Walnut Creek, California); Joseph G. Wallig (Concord, California) |
| ABSTRACT | This application relates to substrate processing systems using mean free path limited species generated in a generation region; a substrate processing chamber including a substrate support system positioned within the mean free path of the mean free path limited species; the substrate processing system having a pumping system for evacuating the contents of the substrate processing chamber; the substrate processing system optionally including a device for throttling the pumping of the substrate processing chamber and optionally including a device for mechanically tuning the distance between the emission point of the mean free path limited species and the substrate. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/174183 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45536 (20130101) C23C 16/45544 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/32082 (20130101) H01J 37/32715 (20130101) H01J 37/32834 (20130101) H01J 2237/3321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246562 | KLEIN, JR. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Walter Ellis KLEIN, JR. (Bailey, Colorado); Kenneth Charles NEYERLIN (Arvada, Colorado) |
| ABSTRACT | The present disclosure relates to an electrochemical flow cell that includes a gap positioned between an ion exchange membrane (IEM) and a cathode gas diffusion electrode (GDE), where the gap is positioned to contain a liquid and the gap has a thickness value, as defined by the distance between the IEM and the cathode GDE, of between greater than zero mm and less than about 2.0 mm. In some embodiments of the present disclosure, the gap may be between about 0.1 mm and about 1.0 mm. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159736 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 9/23 (20210101) Original (OR) Class C25B 11/032 (20210101) C25B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210247557 | Smalyukh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ivan I. Smalyukh (Boulder, Colorado); Andrew Johnston Hess (Louisville, Colorado); Quingkun Liu (Boulder, Colorado); Joshua A. De La Cruz (Denver, Colorado); Blaise Fleury (Boulder, Colorado); Eldho Abraham (Boulder, Colorado); Bohdan Senyuk (Boulder, Colorado); Vladyslav Cherpak (Westminster, Colorado) |
| ABSTRACT | Materials that can be templated by one or more of biological material and biologically-derived material, structures including such materials, and methods of forming and using the materials and structures are disclosed. Exemplary materials and structures can be used to reflect, polarize and/or retard electromagnetic radiation. |
| FILED | Wednesday, June 13, 2018 |
| APPL NO | 17/251675 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/08 (20130101) G02B 5/3083 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210248204 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NAMESFORLIFE, LLC (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles T. Parker (East Lansing, Michigan); Catherine M. Lyons (Edinburgh, United Kingdom); Gerald P. Roston (Saline, Michigan); George M. Garrity (Okemos, Michigan) |
| ABSTRACT | The present invention provides systems and methods for automatically identifying name-like-strings in digital resources, matching these name-like-string against a set of names held in an expertly curated database, and for those name-like-strings found in said database, enhancing the content by associating additional matter with the name, wherein said matter includes information about the names that is held within said database and pointers to other digital resources which include the same name and it synonyms. |
| FILED | Tuesday, January 19, 2021 |
| APPL NO | 17/152429 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/951 (20190101) G06F 16/955 (20190101) G06F 16/3331 (20190101) G06F 16/9566 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249618 | Meshot et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Eric Meshot (Livermore, California); Steven Buchsbaum (Livermore, California) |
| ABSTRACT | Provided is a gated nanostructure device, which includes a thick film comprising a conducting nanoporous material between a source electrode and a drain electrode; and a gate electrode that modulates an electric current through the conducting nanoporous material between the source electrode and the drain electrode throughout a thickness of the thick film. The conducting nanoporous material includes an exposed portion, which is exposed to an external environment, and pores of the conducting nanoporous material are aligned at least partially between the source electrode and the drain electrode. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170685 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/055 (20130101) H01L 51/0558 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249693 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yisi Zhu (Naperville, Illinois); Sanja Tepavcevic (Chicago, Illinois); Justin Grant Connell (Chicago, Illinois); Peter Zapol (Hinsdale, Illinois); Nenad Markovic (Hinsdale, Illinois) |
| ABSTRACT | Solid-state batteries offer improved safety and the high-energy-density capabilities required for next generation demands of electric vehicles. Disclosed is a method for fabricating high-current-density solid-state batteries, and the associated device structures and systems. The method of fabrication includes purifying surfaces of a solid electrolyte, depositing materials to form deposition layers on the surfaces of the solid electrolyte in a vacuum, and forming oxygen-deficient interfaces at the interface of the deposition layers and the solid electrolyte. The methods and associated devices form high-current-density solid-state batteries with stable electrochemical performance over hundreds of electric cycles. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784543 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/405 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 10/0585 (20130101) Original (OR) Class H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249974 | Lorimer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Spark Thermionics, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Lorimer (Emeryville, California); Jared William Schwede (Emeryville, California) |
| ABSTRACT | A system for combined heat and electric power generation, preferably including a heat reservoir and one or more electric generators, each preferably including a heat source and an energy converter. A method for combined heat and electric power generation, preferably including activating an electric generator, deactivating the electric generator, and/or providing heat from a heat reservoir. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170748 |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250525 | Kester |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Timothy Kester (Friendswood, Texas) |
| ABSTRACT | In one embodiment, an infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including an optical focal plane array (FPA) unit. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. Said optical system and said processing unit can be contained together in a data acquisition and processing module configured to be worn or carried by a person. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/302306 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/28 (20130101) G01J 3/0208 (20130101) G01J 3/0232 (20130101) G01J 3/0256 (20130101) G01J 3/0289 (20130101) G01J 3/0297 (20130101) G01J 3/2803 (20130101) G01J 5/02 (20130101) G01J 5/0014 (20130101) G01J 5/026 (20130101) G01J 5/047 (20130101) G01J 5/089 (20130101) G01J 5/0834 (20130101) G01J 2003/104 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3504 (20130101) Optical Elements, Systems, or Apparatus G02B 5/201 (20130101) G02B 5/208 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/209 (20130101) G06K 9/00624 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class H04N 5/2258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20210244023 | KIM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanghoon KIM (Peoria, Illinois); Patrick F. DOWD (Peoria, Illinois) |
| ABSTRACT | The present invention relates to compositions of microencapsulated organic compounds, such as pesticides, including insecticides, and methods of making and using the microcapsules. Encapsulating materials include proteins and degradable polymers. These microencapsulated organic compounds provide, for example, increased effective working time of pesticides, resulting in lowered need for reapplication of the pesticides. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/973292 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) Original (OR) Class A01N 37/08 (20130101) A01N 43/16 (20130101) A01N 43/54 (20130101) A01N 43/90 (20130101) A01N 47/22 (20130101) A01N 47/34 (20130101) A01N 57/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210244809 | GLADUE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Douglas P. GLADUE (GUILFORD, Connecticut); MANUEL V. BORCA (WESTBROOK, Connecticut) |
| ABSTRACT | Provided herein are details on the construction of a recombinant African Swine Fever Virus (ASFV) live attenuated vaccine for prevention of ASF caused by various strains of ASFV, such as the highly virulent Georgia 2007 isolate (“ASFV-G”). An exemplary vaccine comprises the ASFV-GΔI1771 modified virus, a recombinant ASFV-G modified by deleting a portion of the I177L ORF rendering the I177L gene nonfunctional. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/223252 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246343 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Huai N. Cheng (Metairie, Louisiana); Michael K. Dowd (Metairie, Louisiana); Zhongqi He (New Orleans, Louisiana) |
| ABSTRACT | Disclosed herein are adhesive compositions containing a cottonseed protein and a catechol compound containing a carboxyl group, and optionally a carrier. Also disclosed are processes for producing an adhesive composition involving mixing a cottonseed protein and a catechol compound containing a carboxyl group, and optionally a carrier. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144329 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/1207 (20130101) B32B 2309/02 (20130101) B32B 2309/12 (20130101) B32B 2317/16 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 189/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210246416 | Talaat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adel M. Talaat (Madison, Wisconsin) |
| ABSTRACT | Described herein is a mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL, sigE, ECF-1, and mixtures thereof, wherein the GGR gene is at least partially inactivated. Described herein also is a vaccine based on the mutant and a method of differentiating between subjects that have been infected with mycobacterium and subjects that have not been infected with mycobacterium or have been vaccinated with a mycobacterium vaccine. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221605 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 2039/522 (20130101) Peptides C07K 14/35 (20130101) C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class C12N 1/36 (20130101) C12N 15/1031 (20130101) C12N 15/1136 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20210249468 | Heron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Thomas Heron (Saline, Michigan); Peter Benjamin Meisenheimer (Ann Arbor, Michigan); Darrell G. Schlom (Ithaca, New York); Rachel Steinhardt (Brooktondale, New York) |
| ABSTRACT | A heterostructure includes a substrate exhibiting a piezoelectric effect, and a magnetostrictive film supported by the substrate. The magnetostrictive film includes an iron-gallium alloy. The iron-gallium alloy has a gallium composition greater than 20%. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784351 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/20 (20130101) Original (OR) Class H01L 41/20 (20130101) H01L 41/47 (20130101) H01L 41/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210249583 | Najafi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PsiQuantum Corp. (Palo Alto, California); Government of the United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Faraz Najafi (Palo Alto, California); Qiaodan Jin Stone (Sunnyvale, California); Adam Nykoruk McCaughan (Denver, Colorado) |
| ABSTRACT | The various embodiments described herein include methods, devices, and systems for operating superconducting circuits. In one aspect, an electric circuit includes: (1) a superconductor component having a first terminal at a first end and a second terminal at a second end; (2) a gate component thermally-coupled to the superconductor component at a first location between the first terminal and the second terminal, where the gate component is thermally-coupled via a first section of the gate component; and where the gate component has a smallest width at the first section so as to focus resistive heating toward the superconductor component. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/240965 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) H01L 39/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250101 | Gordon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Ari Gordon (Lafayette, Colorado); Christopher Lee Holloway (Boulder, Colorado) |
| ABSTRACT | A quantum atomic receiving antenna includes: a probe laser; a coupling laser; an atomic vapor cell that includes: a spherically-shaped or parallelepiped-shaped atomic vapor space and Rydberg antenna atoms that undergo a radiofrequency Rydberg transition to produce quantum antenna light from probe light such that an intensity of the quantum antenna light depends on an amount of radiofrequency radiation received by the Rydberg antenna atoms, the quantum antenna light including a strength, direction and polarization of the radiofrequency radiation; and a quantum antenna light detector in optical communication with the atomic vapor cell. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173476 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/503 (20130101) H04B 10/532 (20130101) Original (OR) Class H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20210244439 | Frederick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Frederick (Gretna, Nebraska); Shane Farritor (Lincoln, Nebraska); Jack Mondry (Edina, Minnesota); Eric Markvicka (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska); Jacob Greenburg (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning surgical systems or devices into the cavity. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999407 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0218 (20130101) A61B 17/3423 (20130101) Original (OR) Class A61B 17/3498 (20130101) A61B 90/40 (20160201) A61B 2017/3447 (20130101) A61B 2034/302 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250298 | Liaghati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir Leon Liaghati (Huntsville, Alabama); Roderick Howell (Madison, Alabama) |
| ABSTRACT | A system controls a transmission of data. A sensor datum measured by a sensor is received. Whether to send the received sensor datum to a multiplexer is determined based on a predefined real time download rate. When the determination indicates to send the received sensor datum to the multiplexer, the received sensor datum is sent to the multiplexer. When the determination does not indicate to send the received sensor datum to the multiplexer, the received sensor datum is written to a data file. The written sensor datum is sent from the data file to the multiplexer when there is an indicator of excess available bandwidth. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/787719 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/022 (20130101) H04L 47/2416 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/38 (20180201) H04W 28/0215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20210250059 | Roden, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies, Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Gilbert Roden, III (New Windsor, Maryland); John-Francis Mergen (Baltimore, Maryland); Christopher Michael Wilder (Pikesville, Maryland); David Brian Miller, JR. (Washington, District of Columbia) |
| ABSTRACT | An RF clocked device can include a signal processor operable to receive an RF signal having an RF signal frequency and output a clock signal having a clock frequency based on the RF signal frequency. The RF clocked device can also include a clock operable to receive, and operate, using the clock signal. The clock can output at least one of a time and a date. In addition, a clock system can include an RF clocked device. The RF clocked device can include a signal processor operable to receive an RF signal having an RF signal frequency and output a clock signal having a clock frequency based on the RF signal frequency. The RF clocked device can also include a clock operable to receive, and operate, using the clock signal. The clock can output at least one of a time and a date. The clock system can also include a client device operable to receive timing information from the RF clocked device. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/833356 |
| CURRENT CPC | Transmission H04B 1/7073 (20130101) Original (OR) Class H04B 2201/7073 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0331 (20130101) H04L 7/0332 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20210250085 | ZENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dongsong ZENG (Germantown, Maryland); John C. Gonda, III (Falls Church, Virginia) |
| ABSTRACT | Disclosed herein are system, method, and computer program product embodiments for utilizing parallel links to improve sub-network availability and latency performance for ATC traffic. An embodiment operates by receiving a generated message. The type of the generated message is determined, where the type is an air traffic control message or a non-air traffic control message. Based on the type of message, communication links are selected, where the communication links include parallel transmission links or a serial link. The method continues by copying the generated message and transmitting the copied message using the selected communication links. The method waits to receive an acknowledgement indicating receipt of the transmitted message. Upon identifying an acknowledgement, any of the copied messages not yet retransmitted are deleted. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222450 |
| CURRENT CPC | Transmission H04B 7/18506 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 45/245 (20130101) H04L 47/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20210244659 | Myung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); U.S. Government Represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Myung (Stanford, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/251605 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0051 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20210245137 | Myung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Nosang Myung (Oakland, California); David Cwiertny (Iowa City, Iowa); Katherine Greenstein (Iowa City, Iowa); Gene Parkin (Iowa City, Iowa) |
| ABSTRACT | A method is disclosed of forming core-shell iron oxide-polymer nanofiber composites. The method includes synthesizing composite nanofibers of polyacrylonitrile (PAN) with embedded hematite (α-Fe2O3) nanoparticles via a single-pot electrospinning synthesis; and generating a core-shell nanofiber composite through a subsequent hydrothermal growth of α-Fe2O3 nanostructures on the composite nanofibers of polyacrylonitrile (PAN) with the embedded hematite (α-Fe2O3) nanoparticles. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/972958 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/261 (20130101) Original (OR) Class B01J 20/321 (20130101) B01J 20/3078 (20130101) B01J 20/3236 (20130101) B01J 20/3295 (20130101) B01J 20/28004 (20130101) B01J 20/28007 (20130101) B01J 20/28011 (20130101) B01J 20/28028 (20130101) B01J 20/28038 (20130101) B01J 2220/46 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 2101/103 (20130101) C02F 2305/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/1216 (20130101) C23C 18/1237 (20130101) C23C 18/1245 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/08 (20130101) D01F 8/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
MITRE Corporation (MITRE)
| US 20210250085 | ZENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dongsong ZENG (Germantown, Maryland); John C. Gonda, III (Falls Church, Virginia) |
| ABSTRACT | Disclosed herein are system, method, and computer program product embodiments for utilizing parallel links to improve sub-network availability and latency performance for ATC traffic. An embodiment operates by receiving a generated message. The type of the generated message is determined, where the type is an air traffic control message or a non-air traffic control message. Based on the type of message, communication links are selected, where the communication links include parallel transmission links or a serial link. The method continues by copying the generated message and transmitting the copied message using the selected communication links. The method waits to receive an acknowledgement indicating receipt of the transmitted message. Upon identifying an acknowledgement, any of the copied messages not yet retransmitted are deleted. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222450 |
| CURRENT CPC | Transmission H04B 7/18506 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 45/245 (20130101) H04L 47/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20210244911 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky); W-Z Biotech, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dongfang Wang (Lexington, Kentucky); Joseph B. Zwischenberger (Lexington, Kentucky); Guangfeng Zhao (Shenzhen, China PRC); Cherry Ballard-Croft (Lexington, Kentucky) |
| ABSTRACT | A multiple lumen device for percutaneous left ventricular unloading during venoarterial extracorporeal membrane oxygenation comprising: an expandable cage, an outer catheter, and an inner catheter, wherein a proximal end of the expandable cage is attached to the outer catheter and a distal end of the expandable cage is attached to the inner catheter, such that when the proximal end of the inner catheter is retracted, the cage moves from a compressed configuration to an expanded configuration is described. Also provided are methods for causing the blood of a subject to flow in a retrograde manner using a multiple lumen device. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232594 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/003 (20130101) Original (OR) Class A61M 25/0074 (20130101) A61M 2025/0002 (20130101) A61M 2025/0031 (20130101) A61M 2205/0216 (20130101) A61M 2205/3331 (20130101) A61M 2210/125 (20130101) A61M 2210/127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20210247152 | Roberge |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary D. Roberge (Tolland, Connecticut) |
| ABSTRACT | A heat exchanger duct includes a wall having ends spaced along a central axis. An inlet manifold is positioned within a downstream portion of the duct at a radially outward location. An outlet manifold is positioned within an upstream portion of the duct at a radially outward location. At least one of the inlet and outlet manifolds extend at least 10 degrees around the circumference of the duct. A central manifold is disposed between the inlet and outlet manifolds, and radially inwardly of the inlet and outlet manifolds. Heat exchanger entrance elements extend radially inward from the inlet manifold to the central manifold, and heat exchanger exit elements extend radially outward from the central manifold to the outlet manifold. A gas turbine engine is also disclosed. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784630 |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/10 (20130101) F28F 9/22 (20130101) F28F 9/027 (20130101) Original (OR) Class F28F 27/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210250075 | ROBINSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Brandon ROBINSON (Crownsville, Maryland) |
| ABSTRACT | A processor coupled to a first communication device produces and transmits a first encoded vector and a second encoded vector to a second communication device via a communication channel that applies a channel transformation to the encoded vectors during transmission. A processor coupled to the second communication device receives the transformed signals, constructs a matrix based on the transformed signals, detects an effective channel thereof, and identifies left and right singular vectors of the effective channel. A precoding matrix is selected from a codebook of unitary matrices based on a message, and a second encoded vector is produced based on a second known vector, the precoding matrix, a complex conjugate of the left singular vectors, and the right singular vectors. A first symbol of the second encoded vector and a second symbol of the second encoded vector are sent to the first communication device for identification of the message. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/787290 |
| CURRENT CPC | Transmission H04B 7/0417 (20130101) H04B 7/0456 (20130101) H04B 7/0634 (20130101) Original (OR) Class H04B 7/0639 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 12, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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FUNDED BY
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National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page