FedInvent™ Patent Applications
Application Details for Thursday, September 23, 2021
This page was updated on Thursday, September 23, 2021 at 09:31 PM GMT
Department of Health and Human Services (HHS)
| US 20210290074 | ERTIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emre ERTIN (Columbus, Ohio); William T. ABRAHAM (Columbus, Ohio) |
| ABSTRACT | Various examples related to mobile bodily monitoring using ultra-wideband radar are provided. In one example, a method for determining a bodily characteristic includes collecting sets of reflected backscatter data for a sequence of ultra-wideband (UWB) pulses transmitted via an UWB sensor, and a corresponding calibration measurement from a calibration channel; determining reflection coefficients for each tissue interface based on the sets of reflected backscatter data; and determining a fluid level content of the lung tissue based upon the reflection coefficients. The reflection coefficients can be determined from reflection profiles based upon the reflected backscatter data for that sequence of UWB pulses and the corresponding calibration measurement. The UWB sensor can include an array of transmit (TX) and receive (RX) antenna pairs positioned on a body of a user. The reflection profile can be associated with a model of tissue layers in the body between the UWB sensor and lung tissue. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 17/260827 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0205 (20130101) Original (OR) Class A61B 5/0507 (20130101) A61B 5/0537 (20130101) A61B 5/6833 (20130101) A61B 2560/0223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290096 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Deshan Yang (St. Louis, Missouri); Yabo Fu (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of methods and systems for segmenting images and expediting a contouring process for MRI-guided adaptive radiotherapy (MR-IGART) comprising applying a convolutional neural network (CNN), wherein the CNN accurately segments organs (e.g., the liver, kidneys, stomach, bowel, or duodenum) in 3D MR images. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 17/264620 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/201 (20130101) A61B 5/4238 (20130101) A61B 5/4244 (20130101) A61B 5/4255 (20130101) A61B 5/4836 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4808 (20130101) G01R 33/5608 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) G06K 9/6257 (20130101) G06K 9/6264 (20130101) G06K 9/6265 (20130101) G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 2207/10088 (20130101) G06T 2207/20084 (20130101) G06T 2207/30056 (20130101) G06T 2207/30084 (20130101) G06T 2207/30092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290429 | Tai |
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| APPLICANT(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g., 37° C. in a human), such as from 43° C. to 54° C. for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15° C. to 30° C. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339481 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/02 (20130101) A61F 7/007 (20130101) Original (OR) Class A61F 2007/0073 (20130101) A61F 2007/0075 (20130101) A61F 2007/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290433 | SIEVING et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Albert SIEVING (Bethesda, Maryland); Ronald Avery BUSH (Howell, Michigan); Hongman SONG (Rockville, Maryland); Lisa L. WEI (Gaithersburg, Maryland); Yong ZENG (Potomac, Maryland); Henry Ernest WILEY (Bethesda, Maryland) |
| ABSTRACT | Methods of administering a gene therapy construct to the eye including injection of the construct into the eye and application of an electric current to enhance penetration of or cellular expression of molecules in ocular tissues. These methods provide effective technique for the intraocular delivery of gene therapy vectors, especially AAV vectors, and nanoparticles. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 17/260905 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 48/0075 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/30 (20130101) A61N 1/0428 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290524 | Woolf et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Clifford J. Woolf (Newton, Massachusetts); Ajay S. YEKKIRALA (Canton, Massachusetts); Michael COSTIGAN (Cambridge, Massachusetts) |
| ABSTRACT | The technology disclosed herein generally relates to the field of pain relief, and relates to a topical composition comprising a TRPV1 antagonist. The technology disclosed herein provides for methods, compositions and devices for topical application for the treatment of pain, allodynia or hyperalgesia associated with acute tissue injury, e.g., for the treatment of a wounds or tissue injury, including but not limited to incision, abrasion, laceration, puncture and avulsion. The methods, compositions and devices disclosed herein can be used for point-of-care treatment of a tissue injury or wound, e.g., in emergency care for first responders, emergency medical technicians (EMTs), ambulance workers, firemen, in field surgery, combat medicine or casualty care and/or first aid kits. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 16/330682 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) Original (OR) Class A61K 31/357 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290539 | GOURDIE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Robert G. GOURDIE (Roanoke, Virginia); VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (BLACKSBURG, Virginia); VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (Blacksburg, Virginia) |
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| INVENTOR(S) | Robert G. GOURDIE (Roanoke, Virginia); L. JANE JOURDAN (Roanoke, Virginia); Eda ROGERS (Roanoke, Virginia) |
| ABSTRACT | Described herein are engineered hemichannels, engineered vesicles that can contain the one or more of the engineered hemichannels, pharmaceutical formulations thereof, and uses thereof. In some aspects, the engineered vesicles can include one or more cargo molecules. Also described herein are methods of loading the engineered vesicles. In some aspects, loading of one or more cargo molecules engineered vesicles can be optionally via an engineered hemichannel contained in the engineered vesicle. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 17/264793 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1526 (20130101) A23C 9/1528 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0056 (20130101) A61K 9/1271 (20130101) A61K 9/1278 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/46 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/06 (20180101) A61P 17/02 (20180101) A61P 25/00 (20180101) A61P 27/02 (20180101) Peptides C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290545 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Velico Medical Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); Junqing Cui (West Roxbury, Massachusetts); Rud Karly Lucien (Lynn, Massachusetts); Ryan Carney (Hudson, New Hampshire); Jihae Sohn (Brighton, Massachusetts); Michelle Arya (Medford, Massachusetts) |
| ABSTRACT | A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/337306 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/1617 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 9/1688 (20130101) A61K 35/16 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/06 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/04 (20130101) F26B 3/06 (20130101) F26B 3/12 (20130101) F26B 5/04 (20130101) F26B 5/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290569 | Rubin et al. |
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| FUNDED BY |
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| APPLICANT(S) | MESHABERASE, LLC (Potomac, Maryland); United States Department of Health and Human Services, National Institutes of Health (Bethesda, Maryland) |
| ASSIGNEE(S) | MESHABERASE, LLC (Potomac, Maryland); United States Department of Health and Human Services, National Institutes of Health (Bethesda, Maryland) |
| INVENTOR(S) | Benjamin Rubin (Potomac, Maryland); Mark Gilbert (Bethesda, Maryland); Jinkyu Jung (Bethesda, Maryland) |
| ABSTRACT | The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/337095 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/28 (20130101) A61K 9/0053 (20130101) A61K 9/4891 (20130101) A61K 31/145 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290571 | Soma et al. |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shivatheja Soma (College Station, Texas); Vishal M. Gohil (College Station, Texas); James C. Sacchettini (College Station, Texas); Liam Guthrie (College Station, Texas) |
| ABSTRACT | In an embodiment, the present disclosure relates to a method of restoring cytochrome c oxidase (CcO) activity in a subject in need thereof. In some embodiments, the method includes administering a therapeutically effective amount of elesclomol or analog thereof and rescuing defects of cells in the subject with deficiencies or mutations in at least one of SOD1, AT-1, API SI, COA6, SC02, COX6B1, CTRL ATOX1, CCS, GSX1, ATP7A, ATP7B, CLCN5, and CLCN7. In a further embodiment, the present disclosure relates to a method of treating disorders of copper metabolism. In some embodiments, the method includes administering a therapeutically effective amount of elesclomol or analog to a subject, where the disorder is caused by a deficiency or mutation to a gene including, without limitation, SOD1, AT-1, API SI, COA6, SC02, COX6B1, CTR1, ATOX1, CCS, GSX1, ATP7A, ATP7B, CLCN5, CLCN7, or combinations thereof. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 17/257770 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) Original (OR) Class A61K 33/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290593 | Jacobsen et al. |
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| APPLICANT(S) | Duke University (Durham, North Carolina); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob P.R. Jacobsen (Durham, North Carolina); Marc G. Caron (Hillsborough, North Carolina); Michael Gershon (New York, New York); Kara Margolis (New York, New York) |
| ABSTRACT | The present invention provides, inter alia, methods for treating or ameliorating a gastrointestinal (GI) condition such as constipation in a subject in need thereof, using a sustained release formulation of 5-hydroxytryptophan (5-HTP SR). A kit comprising 5-HTP SR is also provided. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 17/250350 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/405 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290602 | SHARMA et al. |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
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| INVENTOR(S) | Manu SHARMA (Tappan, New York); Nima N. NASERI (Philadelphia, Pennsylvania) |
| ABSTRACT | The present technology relates to methods for treating, preventing, and/or ameliorating diseases associated with ectopic iron-sulfur (Fe—S) cluster formation or ectopic iron-sulfur (Fe—S) cluster binding, such as adult-onset neuronal ceroid lipofuscinosis (ANCL or Kufs disease) comprising administering a therapeutically effective amount of an iron chelator to a subject in need thereof. Kits for use in practicing the methods are also provided. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155200 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 31/16 (20130101) A61K 31/44 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290615 | Cox et al. |
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| APPLICANT(S) | Sistema Universitario Ana G. Mendez, Inc. (San Juan, Puerto Rico) |
| ASSIGNEE(S) | Sistema Universitario Ana G. Mendez, Inc. (San Juan, Puerto Rico) |
| INVENTOR(S) | Osvaldo Cox (Humacao, Puerto Rico); Beatriz Zayas (San Juan, Puerto Rico) |
| ABSTRACT | A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343503 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290652 | Shay et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jerry Shay (Dallas, Texas); Yang-Xin Fu (Dallas, Texas); Ilgen Mender (Dallas, Texas); Anli Zhang (Dallas, Texas) |
| ABSTRACT | Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. eads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and humanized mouse cancer models. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200539 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290653 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York); Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allen Tingjin Yu (Pleasanton, California); David L. Spector (Cold Spring Harbor, New York); Frank Rigo (Carlsbad, California); Susan M. Freier (San Diego, California); Jan Bergmann (Basel, Switzerland); Carmen Berasain (Pamploma, Spain) |
| ABSTRACT | Provided herein are methods, compounds, and compositions for reducing expression of lnc05 in a cell or individual. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate a cancer in an individual. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/337762 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/7125 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290669 | DUNHAM et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hemanext Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | Hemanext Inc. (Lexington, Massachusetts) |
| INVENTOR(S) | Andrew DUNHAM (Lexington, Massachusetts); Tatsuro YOSHIDA (Lexington, Massachusetts) |
| ABSTRACT | Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. Methods for restoring mean arterial pressure to a normal range and reducing trauma adverse risks in a patient through the administration of oxygen reduced blood compositions. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339283 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290705 | van den Pol |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
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| INVENTOR(S) | Anthony N. van den Pol (Branford, Connecticut) |
| ABSTRACT | Chimeric viruses having a vesicular stomatitis virus (VSV) background where the VSV G protein is supplemented or replaced with an alphavirus glycoprotein(s), or a functional fragment(s) thereof, are provided. A preferred alphavirus is Chikungunya virus. In particular embodiments, the glycoprotein(s) is or includes E3, E2, K6, and E1 proteins of an alphavirus, preferably Chikungunya virus. Methods of using the chimeric viruses for treatment of cancers, particularly brain cancers and metastasis thereof are also provided. In some embodiments, the chimeric viruses retain superior oncolytic activity to infect and destroy cancer cells selectively, such as glioblastoma and intracranial melanoma metastases. In some embodiments, the chimeric viruses have reduced toxicity to e.g., heathy cells relative to a control such as the parent VSV with the VSV G protein. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 17/260930 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/766 (20130101) Original (OR) Class A61K 38/162 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290724 | Udugamasooriya et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Damith Gomika Udugamasooriya (Katy, Texas); Aaron Raymond (Houston, Texas); John Minna (Dallas, Texas) |
| ABSTRACT | Described herein are pharmaceutical compositions containing peptoids of general formula (I), (II), or (III) capable of reducing proliferation of cancer stem cells in a subject and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat cancer. Also provided herein are method of detecting and treating cancerous cell masses by use of peptoids of general formula (I), (II), or (III). |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 16/334528 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290727 | Ahmed et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zubair M. Ahmed (Ellicott City, Maryland); Saumil Sethna (Baltimore, Maryland); Saima Riazuddin (Ellicott City, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Zubair M. Ahmed (Ellicott City, Maryland); Saumil Sethna (Baltimore, Maryland); Saima Riazuddin (Ellicott City, Maryland) |
| ABSTRACT | Provided herein are compositions and methods for down-regulating mTORC1 signaling in a subject, comprising administering to the subject an effective amount of one or more compositions that promote increased levels or activity of CIB32 or a biologically active fragment or variant thereof in the subject. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 17/264939 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 35/76 (20130101) A61K 38/465 (20130101) A61K 38/1738 (20130101) Original (OR) Class A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 35/00 (20180101) Peptides C07K 14/4728 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290731 | McLaughlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tracey L. McLaughlin (Stanford, California); Colleen M. Craig (Stanford, California) |
| ABSTRACT | Treatment of hyperinsulinemic hypoglycemia comprises administration of an effective amount of a glucagon-like peptide-1 receptor antagonist (GLP1RA) alone or in combination with an amylinomimetic agent or any anti-gastric emptying agent. Patients suffering from hyperinsulinemic hypoglycemia after bariatric surgery experience particular benefit, as there is no current method effective for their treatment. Prevention or reduction of acute adverse effects of postprandial hypoglycemia, such as palpitations, tremor, weakness, sweating, confusion, fatigue, blurred vision, seizures, or loss of consciousness, and prevention of chronic adverse effects of hyperinsulinemic hypoglycemia, such as cognitive impairment, can be achieved by treatment with GLP1RA. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/226161 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 38/17 (20130101) A61K 38/22 (20130101) A61K 38/26 (20130101) A61K 38/2278 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290748 | Schneewind et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olaf Schneewind (Chicago, Illinois); Alice G. Cheng (Boston, Massachusetts); Dominique M. Missiakas (Chicago, Illinois); Hwan Keun Kim (Chicago, Illinois) |
| ABSTRACT | The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340532 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 37/04 (20180101) Peptides C07K 14/31 (20130101) C07K 16/1271 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290749 | Kinney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Claire Y. H. Kinney (Fort Collins, Colorado) |
| ABSTRACT | Chimeric flaviviruses that include non-coding regions, non-structural proteins, a capsid (C) protein and a portion of a premembrane (prM) signal sequence from an attenuated or wild-type dengue serotype 2 virus (DENV-2), and a portion of a prM signal sequence, a prM protein and at least a portion of an envelope (E) protein from a Zika virus (ZIKV) are described. Also described are immunogenic compositions and methods for eliciting an immune response in a subject, such as an immune response directed against ZIKV. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 16/316005 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5252 (20130101) Peptides C07K 14/1816 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290754 | Kawaoka et al. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yoshihiro Kawaoka et al. (Middleton, Wisconsin); Peter J. Halfmann (Madison, Wisconsin) |
| ABSTRACT | The invention provides a vaccine comprising a recombinant biologically contained filovirus and methods of making and using those viruses. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 17/266049 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/70 (20130101) Peptides C07K 16/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290761 | Davis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Prommune, Inc. (Topeka, Kansas); Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Davis (Omaha, Nebraska); Samer Al-Murrani (Overland Park, Kansas) |
| ABSTRACT | Anti-parasitic compounds and uses thereof. Compounds comprising a C-terminal peptide adjuvant conjugated to an N-terminal peptide antigen via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism, such as T. gondii. Methods of therapeutic or prophylactic treatment of a parasitic infections. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 17/275892 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/002 (20130101) A61K 39/005 (20130101) A61K 39/008 (20130101) A61K 39/012 (20130101) A61K 39/015 (20130101) A61K 39/018 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/627 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290778 | de los Pinos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Aura Biosciences, Inc. (Cambridge, Massachusetts); The USA, as Represented by the Secretary, Department of Health and Human Service (Bethesda, Massachusetts) |
| ASSIGNEE(S) | Aura Biosciences, Inc. (Cambridge, Massachusetts); The USA, as Represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland) |
| INVENTOR(S) | Elisabet de los Pinos (Brookline, Massachusetts); John Todd Schiller (Kensington, Maryland); Rhonda C. Kines (Washington, District of Columbia) |
| ABSTRACT | Some embodiments of the present disclosure are directed to methods and compositions for the treatment of tumors, using a combination of immunotherapeutic agents and tumor-targeting viral capsid protein assemblages comprising anti-cancer molecules conjugated to viral capsid proteins. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 16/604790 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 41/0061 (20130101) A61K 41/0071 (20130101) A61K 41/0076 (20130101) A61K 47/6901 (20170801) Original (OR) Class A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290779 | COHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); MONELL CHEMICAL SENSES CENTER (Philadelphia, Pennsylvania); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AF (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); MONELL CHEMICAL SENSES CENTER (Philadelphia, Pennsylvania); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AF (Washington, District of Columbia) |
| INVENTOR(S) | Noam A COHEN (Bala Cynwyd, Pennsylvania); Robert J. LEE (Pittsburgh, Pennsylvania); Danielle R. REED (Glenside, Pennsylvania) |
| ABSTRACT | The invention provides methods and compositions for the diagnosis, prognosis and treatment of respiratory tract diseases. Specifically, the invention provides diagnosis, prognosis and treatment of respiratory infections using bitter and sweet taste signal transduction pathways. In one aspect, the invention relates to a method for treating a respiratory infection by administering a composition to the respiratory tract of a subject in an amount capable of activating bitter taste signaling and/or inhibiting sweet taste signaling. The composition comprises at least a bitter receptor agonist and, optionally, a pharmaceutically acceptable carrier for delivering the composition to the respiratory tract. In another aspect, the invention relates to a composition for treatment of a respiratory infection. Such composition comprises at least a bitter receptor agonist and, optionally, a pharmaceutically acceptable carrier for delivering the composition to the respiratory tract. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/111158 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/233 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/0014 (20130101) A61K 9/0043 (20130101) A61K 31/167 (20130101) A61K 31/365 (20130101) A61K 31/513 (20130101) A61K 31/4709 (20130101) A61K 36/185 (20130101) A61K 49/0004 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290780 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew S. Freeman (Cincinnati, Ohio); Bastiaan Driehuys (Chapel Hill, North Carolina) |
| ABSTRACT | Systems, methods and related devices used to produce and collect polarized noble gas to inhibit, suppress, detect or filter alkali metal nanoclusters to preserve or increase a polarization level thereof. The systems can include a pre-sat chamber that has an Area Ratio between 20 and 500. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/331990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/06 (20130101) Original (OR) Class A61K 49/18 (20130101) Non-metallic Elements; Compounds Thereof; C01B 23/00 (20130101) C01B 23/0036 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290781 | Chekmenev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eduard Y. Chekmenev (Troy, Michigan); Baptiste Joalland (Hamtramck, Michigan); Nuwandi M. Ariyasingha (Rochester Hills, Michigan) |
| ABSTRACT | A RASER-inducing contrast agent for magnetic resonance (MR) modalities that includes a parahydrogen addition to unsaturated molecular precursor that renders radio amplification by stimulated emission of radiation (RASER) of protons and other nuclear spins. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/202454 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290784 | Horti et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew G. Horti (Ellicott City, Maryland); Ravi Naik (Baltimore, Maryland); Robert F. Dannals (Sparks, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | Positron emission tomography (PET) radiotracers for imaging macrophage colony stimulating factor-1 receptors in a subject afflicted with or suspected of being afflicted with a neuroinflammatory or neurodegenerative disease or disorder are disclosed. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/253336 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0459 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290829 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Konstantinos Tsioris (Somerville, Massachusetts); Fiorenzo G. Omenetto (Lexington, Massachusetts); Eleanor M. Pritchard (New Orleans, Louisiana) |
| ABSTRACT | A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173289 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/205 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 31/125 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 37/0015 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290973 | Moore-Ede et al. |
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| FUNDED BY |
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| APPLICANT(S) | CIRCADIAN ZIRCLIGHT INC. (Stoneham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin Moore-Ede (Wellesley, Massachusetts); Doros Platika (Charleston, Massachusetts); Anneke Heitmann (Arlington, Massachusetts); Rainer Guttkuhn (Maynard, Massachusetts); John Luciani (Wakefield, Massachusetts) |
| ABSTRACT | Methods and apparatus for circadian lighting are disclosed. In particular, improved lighting is described in relation to a novel definition of an optimum relative circadian spectral sensitivity distribution (“Circadian Potency SSD”) with a peak sensitivity at approximately 470 nm-480 nm (preferable embodiments at 472 nm or 478 nm) with a full width at half maximum (“FWHM”) of approximately 50 nm which is skewed asymmetrically between approximately 440 nm and approximately 490 nm. Methods and approaches to determine the Circadian Potency of light sources from their spectral power distributions (SPD) and use the CircadianPotency SSD to optimize healthy circadian function under normal indoor and outdoor illumination conditions are described herein, and incorporated into various light sources, including white light sources, dimmable light sources, and daytime/nighttime light sources. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 17/260215 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2021/0044 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0618 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291137 | Qing et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Quan Qing (Chandler, Arizona); Ching-wei Tsao (Tempe, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising a top surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/257816 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00317 (20130101) B01J 2219/00529 (20130101) B01J 2219/00596 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00822 (20130101) B01J 2219/00853 (20130101) B01J 2219/00855 (20130101) Peptides C07K 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291355 | LERNER et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northen Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Forest LERNER (Flagstaff, Arizona); Greg OREKHOV (Flagstaf, Arizona); Jason LUQUE (Flagstaff, Arizona) |
| ABSTRACT | A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207317 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/5061 (20130101) A61H 2201/5071 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292309 | Wender et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Wender (Stanford, California); Ryan Quiroz (Boston, Massachusetts); Stephen Ho (Stanford, California); Akira Shimizu (Stanford, California); Steven Ryckbosch (Albany, California); Matthew C. Stevens (Atherton, California); Matthew S. Jeffreys (King of Prussia, Pennsylvania); Clayton Hardman (Stanford, California); Jack Sloane (Stanford, California) |
| ABSTRACT | Methods for preparing a variety of bryostatin compounds are provided. The subject methods provide for preparation of bryostatin 1 in multi-gram quantities in a low and unprecedented number of convergent synthetic steps from commercially available materials. The subject methods are scalable with low estimated material costs and can provide enough material to meet clinical needs. Also provided are a variety of bryostatin analog compounds, and prodrug forms thereof, which are synthetically accessible via the subject methods and pharmaceutical compositions including the same. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162554 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) A61K 31/365 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 407/14 (20130101) Original (OR) Class C07D 493/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292310 | Morris et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Joel Morris (Rockville, Maryland); Donn G. Wishka (Middletown, Maryland); Omar Diego Lopez (Walkersville, Maryland) |
| ABSTRACT | Halogenated analogs of 5-aza-2′-deoxycytidine, such as halogenated analogs of 5-aza-4′-thio-2′-deoxycytidine (5-aza-T-dCyd) are described. Pharmaceutical compositions including a halogenated analog and methods of using the halogenated analogs to inhibit neoplasia are described. In some examples, the halogenated analogs have a structure according to formula Ia, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof: |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343350 |
| CURRENT CPC | Heterocyclic Compounds C07D 409/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292325 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Eric Fischer (Chestnut Hill, Massachusetts); Zhixiang He (Brookline, Massachusetts); Guangyan Du (Jamaica Plain, Massachusetts); Katherine Donovan (Boston, Massachusetts); Radoslaw Nowak (Boston, Massachusetts); Jing Ting Christine Yuan (Brookline, Massachusetts) |
| ABSTRACT | Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/255734 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 405/14 (20130101) C07D 473/16 (20130101) Original (OR) Class C07D 473/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292326 | Ha et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ya Ha (Mamaroneck, New York); Jonathan Ellman (Guilford, Connecticut); Song Chen (New Haven, Connecticut); Caroline Chandra Tjin (Boston, Massachusetts); Fabrizio Micheli (Verona, Italy); Agostino Cianciulli (Verona, Italy); Claudia Beato (Verona, Italy) |
| ABSTRACT | The present-disclosure relates to the discovery of novel 2-amino-dihydropteridinone compounds and analogues thereof, which are capable of inhibiting phosphatidylinositol phosphate kinases. In certain embodiments, the compounds of the present disclosure can be used to treat p53-null cancer in a subject. In other embodiments, the compounds of the present disclosure can be used to treat metabolic disorders in a subject, including but not limited to type 2 diabetes and/or obesity. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 17/267488 |
| CURRENT CPC | Heterocyclic Compounds C07D 475/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292335 | Ye |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keqiang Ye (Atlanta, Georgia) |
| ABSTRACT | In certain embodiments, the disclosure relates to heterocyclic flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing diseases or conditions related to BDNF and TrkB activity, such as depression, stroke, Rett syndrome, Parkinson's disease, and Alzheimer's disease by administering effective amounts of pharmaceutical compositions comprising compounds disclosed herein to a subject in need thereof. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 17/266863 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 491/052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292352 | Eberwine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Eberwine (Philadelphia, Pennsylvania); Ivan J. Dmochowski (Philadelphia, Pennsylvania); Sean B. Yeldell (Philadelphia, Pennsylvania); Julianne C. Griepenburg (Philadelphia, Pennsylvania); Teresa L. Rapp (Philadelphia, Pennsylvania); Jennifer M. Singh (Havertown, Pennsylvania); Jai-Yoon Sul (Cherry Hill, New Jersey); Jaehee Lee (Wynnewood, Pennsylvania) |
| ABSTRACT | Compositions and methods of capturing one or more nucleic acid molecules of a cell or subcellular compartment are described. In certain aspects, the compositions comprise a caged molecule comprising one or more photolinkers and an antisense oligonucleotide, which when uncaged hybridizes to a target nucleic acid molecule. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/333376 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) B01J 2531/821 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/32 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2310/3233 (20130101) C12N 2310/3517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6823 (20130101) C12Q 1/6825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292366 | KRISHNA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REALTA HOLDINGS, LLC (Norfolk, Virginia) |
| ASSIGNEE(S) | REALTA HOLDINGS, LLC (Norfolk, Virginia) |
| INVENTOR(S) | Neel K. KRISHNA (Norfolk, Virginia); Kenji CUNNION (Norfolk, Virginia) |
| ABSTRACT | The present invention provides peptide compounds that regulate the complement system and methods of using these compounds. The invention is an isolated, purified peptide of 30 amino acids derived from human astrovirus protein, called CP1. The invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of CP1 having, for example, internal peptide deletions and substitutions, deletions and substitutions at the N-terminus and C-terminus, and that are able to regulate complement activation. The invention further provides pharmaceutical compositions of therapeutically effective amounts of the peptide compounds and a pharmaceutically acceptable carrier, diluent, or excipient for treating a disease or condition associated with complement-mediated tissue damage. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/337950 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/03 (20130101) A61K 38/10 (20130101) A61K 38/162 (20130101) A61K 45/06 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/005 (20130101) C07K 14/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292370 | Adachi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kei Adachi (Portland, Oregon); Xiao Lan Chang (Portland, Oregon); Hiroyuki Nakai (Portland, Oregon) |
| ABSTRACT | Human anti-AAV capsid polyclonal antibody conformational epitopes including those of neutralizing antibodies are provided. The epitopes can be recognized by human anti-AAV2 or other AAV strain-derived capsid polyclonal antibodies. One or more of the epitopes may be mutated to form AAV2 and other AAV strain-derived capsids that can escape antibody neutralization. Methods of identifying human anti-AAV capsid polyclonal antibody conformational epitopes are also provided. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/088977 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 2750/14122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292388 | Hirsch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Louis Hirsch (Chapel Hill, North Carolina); Brian Christopher Gilger (Raleigh, North Carolina) |
| ABSTRACT | This invention relates to vectors for delivery of human leukocyte antigen G to the eye and/or to cornea explants and methods of using the same for treatment and/or prevention of corneal transplant rejection and other disorders associated with an immune response and/or vascularization. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 16/318070 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 37/06 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292393 | WESTENDORF et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Hunman Servi (Bethesda, Maryland) |
| ASSIGNEE(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Hunman Servi (Bethesda, Maryland) |
| INVENTOR(S) | Kathryn WESTENDORF (Vancouver, Canada); Stefanie ZENTELIS (Vancouver, Canada); Krithika MUTHURAMAN (Toronto, Canada); Kevin JEPSON (Vancouver, Canada); Ester FALCONER (Vancouver, Canada); John MASCOLA (Bethesda, Maryland); Barney GRAHAM (Bethesda, Maryland); Kizzmekia CORBETT (Bethesda, Maryland); Julie LEDGERWOOD (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Olubukola ABIONA (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Wing-pui KONG (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Bryan Edward JONES (San Diego, California); Denisa FOSTER (San Diego, California); Julian DAVIES (La Jolla, California); Qing CHAI (San Diego, California); Christopher Carl FRYE (Bargersville, Indiana); Ganapathy GOPALRATHNAM (Fishers, Indiana); Jörg HENDLE (San Diego, California); John Michael SAUDER (Carlsbad, California); Jeffrey Streetman BOYLES (Indianapolis, Indiana); Anna PUSTILNIK (San Diego, California) |
| ABSTRACT | Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) A61K 47/6801 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292394 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F.. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Carlisle, Massachusetts); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for antibodies useful for filovirus infections. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/135525 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 2317/76 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292400 | HAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yiping W. HAN (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yiping W. HAN (Bronx, New York); Piero D. DALERBA (New York, New York) |
| ABSTRACT | The present invention relates to treating cancer including colorectal cancer (CRC) by inhibiting or blocking Annexin 1. The present invention also relates to preventing CRC in a patient at high risk by inhibiting or blocking Annexin A1. The present invention also relates to reducing chemo-resistance by inhibiting or blocking Annexin A1. The present invention also relates to detecting a poor prognosis in a subject with CRC by detecting or measuring the expression level of ANXA1 and/or the level of Annexin 1 protein. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/055962 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292428 | Ho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Nan Li (Laurel, Maryland); Bryan D. Fleming (Bethesda, Maryland) |
| ABSTRACT | Monoclonal antibodies that bind glypican-2 (GPC2) with high affinity are described. Immunotoxins and chimeric antigen receptors (CARs) that include the disclosed antibodies or antigen-binding fragments thereof are further described. In some instances, the antibody or antigen-binding fragment is humanized. The disclosed GPC2-specific antibodies and conjugates can be used, for example, for the diagnosis or treatment of GPC2-positive cancers, including neuroblastoma, medulloblastoma and retinoblastoma. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 17/266419 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6829 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292433 | LI |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| INVENTOR(S) | Zihai LI (Mount Pleasant, South Carolina) |
| ABSTRACT | Isolated or recombinant monoclonal antibodies that bind to GARP are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. Further provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of an anti-platelet agent and a T cell therapy. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/327967 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0019 (20130101) A61K 31/675 (20130101) A61K 31/7076 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/34 (20130101) Original (OR) Class C07K 16/2827 (20130101) C07K 16/2866 (20130101) C07K 16/3015 (20130101) C07K 16/3046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292711 | Riddell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Stanley R. Riddell (Seattle, Washington); Irwin D. Bernstein (Seattle, Washington); Margot J. Pont (Seattle, Washington) |
| ABSTRACT | The disclosure provides in some aspect methods and compositions related to culturing and engineering T cells that maintain less differentiated state. The T cells are cultured in conditions that induce Notch signaling The resulting T cells exhibit maintenance of a less differentiated state for prolonged periods and have reduced susceptibility to exhaustion. Also provided are the cells produced by the methods, as well as related compositions and methods of use for adoptive therapy. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 17/272117 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292721 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ABSTRACT | Engineered or non-naturally occurring systems and compositions comprising a novel Cas12b and a guide molecule. Also provided include methods of use the systems and compositions, including in treating and diagnosing diseases. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/894678 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/1276 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292735 | Brangwynne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Cliff Brangwynne (Hopewell, New Jersey); Jared Toettcher (Princeton, New Jersey); Yongdae Shin (Lawrenceville, New Jersey) |
| ABSTRACT | A protein construct including a gene encoding a light-sensitive protein fused to at least one of either a low complexity sequence, an intrinsically disordered protein region (IDR), or a repeating sequence of a linker and another gene encoding a light-sensitive protein. Among the many different possibilities contemplated, the protein construct may also advantageously include cleavage tags. This protein construct may be utilized for a variety of functions, including a method for protein purification, which requires introducing the protein construct into a living cell, and inducing the formation of clusters by irradiating the construct with light. The method may also advantageously include cleaving a target protein from an IDR, and separating the clusters via centrifuge. A kit for practicing in vivo aggregation or liquid-liquid phase separation is also included, the kit including the protein construct and a light source capable of producing a wavelength that the light-sensitive protein will respond to. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338819 |
| CURRENT CPC | Peptides C07K 1/32 (20130101) C07K 14/43595 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class C12N 13/00 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Enzymes C12Y 401/99003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292758 | Tomarev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Stanislav Ivanovich Tomarev (Kensington, Maryland); Benjamin Frank John Martin Mead (Wales, United Kingdom) |
| ABSTRACT | Methods are disclosed herein for treating glaucoma in a subject. In some embodiments, the methods increase retinal ganglion cell survival. The disclosed methods use exosomes and/or miRNA. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/341057 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/498 (20130101) A61K 31/4178 (20130101) A61K 31/5377 (20130101) A61K 31/5575 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292786 | Weissman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Katalin Kariko (Rydal, Pennsylvania) |
| ABSTRACT | This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338795 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/52 (20130101) C07K 14/475 (20130101) C07K 14/505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 2310/335 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292794 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng ZHANG (Cambridge, Massachusetts); Chie-yu LIN (Cambridge, Massachusetts); Fei RAN (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in prokaryotic and eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/321872 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292810 | Bignell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Illumina Cambridge Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Helen Bignell (Cambridge, United Kingdom); Louise Fraser (Cambridge, United Kingdom); Niall Anthony Gormley (Cambridge, United Kingdom) |
| ABSTRACT | The invention relates to methods for indexing samples during the sequencing of polynucleotide templates, resulting in the attachment of tags specific to the source of each nucleic acid sample such that after a sequencing run, both the source and sequence of each polynucleotide can be determined. Thus, the present invention pertains to analysis of complex genomes (e.g., human genomes), as well as multiplexing less complex genomes, such as those of bacteria, viruses, mitochondria, and the like. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/186571 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292823 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for rapid diagnostics related to the use of isothermal amplification reagents for detection of microbial species, including coronavirus, and methods of use, are provided. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/894664 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 7/52 (20130101) B01L 2300/0816 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292824 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts); Julia Joung (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Han Altae-Tran (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for rapid diagnostics related to the use of CRISPR effector systems and optimized guide sequences for detection of coronavirus, including multiplex lateral flow diagnostic devices and methods of use, are provided. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/894670 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292837 | Johnson-Buck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Bio-Rad Laboratories, Inc. (Hercules, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Johnson-Buck (Ann Arbor, Michigan); Nils Walter (Ann Arbor, Michigan); Muneesh Tewari (Ann Arbor, Michigan); William Bradley Strong (El Cerrito, California); Kenneth J. Oh (Pleasant Hill, California); Evan Thrush (San Anselmo, California); Ning Liu (Walnut Creek, California) |
| ABSTRACT | Provided herein is technology relating to the detection of analytes and particularly, but not exclusively, to methods, systems, compositions, and kits for detecting analytes such as nucleic acids, proteins, small molecules, metabolites, and other molecules using a technology based on the transient binding of detection probes in combination with a microfluidic device and/or a nanoparticle. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193060 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6834 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292842 | SYMMANS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William Fraser SYMMANS (Houston, Texas); Bruno SINN (Berlin, Germany); Christos HATZIS (Guilford, Connecticut); Chunxiao FU (Pearland, Texas); Rosanna LAU (Houston, Texas) |
| ABSTRACT | Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESRI) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/097102 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/566 (20130101) A61K 31/4196 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292843 | SMITH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Molly SMITH (Cincinnati, Ohio); Daniel STARCZYNOWSKI (Cincinnati, Ohio); Kakajan KOMUROV (West Chester, Ohio) |
| ABSTRACT | Methods and compositions disclosed herein generally relate to compositions and methods for the treatment of cancers, including disorders such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In particular, the invention relates to determining an individual in need of treatment who can be treated with an IRAK1/4 inhibitor. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 16/339692 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292846 | Rigoutsos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isidore Rigoutsos (Astoria, New York); Eric Londin (Wynnewood, Pennsylvania); Rogan G. Magee (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides a method for assessing whether a uveal melanoma (UVM) patient has, or is at risk of developing a condition, the method comprising measuring the abundance of at least two isomiRs, and/or at least one tRNA derived fragment (tRF), in a biological sample obtained from the patient, and computing the difference in abundance of the at least two isomiRs and at least one tRF as an indication that the subject either has, or is at risk of developing, or is at a given stage of the condition. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206796 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/178 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293674 | Zhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Li Zhan (Saint Paul, Minnesota); Shuang-Zhuang Guo (Minneapolis, Minnesota); Shweta Narayan (Minneapolis, Minnesota); Cari Dutcher (North Oaks, Minnesota); Michael McAlpine (Minneapolis, Minnesota); Kanav Khosla (Minneapolis, Minnesota); John Bischof (St. Paul, Minnesota) |
| ABSTRACT | A cryopreservation system for biological samples is provided. Tire cryopreservation system includes a cooling platform 100 with a 3D printing device that enables a “pick and print” method for processing biological samples 140 for cryopreservation. A syringe or syringes 110 in the 3D printing device picks up biological samples and prints them into a cryogenic environment. A sorting station 200 sorts vitrified samples from unvitrified samples. A warming platform 300 warms the samples using a laser warming system. The cryopreservation system with the sorting station and warming platform are configured for high throughput. Methods for cooling, sorting and warming the biological samples in a high throughput manner are also provided. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 17/262126 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/022 (20130101) B01L 3/502761 (20130101) B01L 7/50 (20130101) B01L 2200/143 (20130101) B01L 2200/0652 (20130101) B01L 2300/023 (20130101) B01L 2300/0819 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 1/44 (20130101) G01N 1/2806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293677 | Gallippi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Caterina M Gallippi (Cary, North Carolina); Christopher Joseph Moore (Durham, North Carolina); Joseph Brickey Richardson (Chapel Hill, North Carolina) |
| ABSTRACT | A method for quantitatively measuring a physical characteristic of a material includes applying a force to a material sample according to an interrogation profile comprising a set of one or more interrogation parameters. The method further includes measuring a displacement over time of the material sample that occurs as a result of applying the force according to the interrogation profile. The method further includes using the interrogation profile and the measured displacement over time of the material sample to derive a quantitative value of a physical characteristic of the material sample. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204919 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/062 (20130101) G01N 3/068 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2203/04 (20130101) G01N 2203/005 (20130101) G01N 2203/0094 (20130101) G01N 2203/0605 (20130101) G01N 2203/0617 (20130101) G01N 2203/0641 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293748 | Gundlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jens Gundlach (Seattle, Washington); Ian Michael Derrington (Seattle, Washington); Andrew Laszlo (Seattle, Washington); Jonathan Craig (Seattle, Washington); Henry Brinkerhoff (Seattle, Washington) |
| ABSTRACT | Methods for nanopore-based protein analysis are provided. The methods address the characterization of a target protein analyte, which has a dimension greater than an internal diameter of the nanopore tunnel, and which is also physically associated with a polymer. The methods further comprise applying an electrical potential to the nanopore system to cause the polymer to interact with the nanopore tunnel. The ion current through the nanopore is measured to provide a current pattern reflective of the structure of the portion of the polymer interacting with the nanopore tunnel. This is used as a metric for characterizing the associated protein that does not pass through the nanopore. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/202118 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 33/6818 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293790 | MATSUNAMI |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hiro MATSUNAMI (Durham, North Carolina) |
| ABSTRACT | The present invention relates to an odorant receptor based odorant sensor system and related methods. In particular, systems and methods are provided permitting detection and discrimination of an odorant molecule in a vapor/gaseous phase using a panel of odorant receptors expressed in heterologous cells. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340804 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20210293794 — METABOLIC BIOMARKERS FOR THE IDENTIFICATION AND CHARACTERIZATION OF ALZHEIMERS DISEASE
| US 20210293794 | Jia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF HAWII CANCER CENTER (Honolulu, Hawaii) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei Jia (Honolulu, Hawaii); Matthias Arnold (Neuherberg, Bavaria, Germany); Gabi Kastenmueller (Neuherberg, Bavaria, Germany); Kwangsik Nho (Indianapolis, Indiana); Andrew J. Saykin (Indianapolis, Indiana); Siamak Mahmoudian Dehkordi (Raleigh, North Carolina); Rima F. Kaddurah-Daouk (Belmont, Massachusetts); Gregory Louie (Durham, North Carolina); Therese Koal (Innsbruck, Austria) |
| ABSTRACT | Embodiments of the present disclosure relate generally to the analysis of broad metabolic changes associated with neurological disorders. In particular, the present disclosure provides materials and methods relating to the use of metabolomics as a biochemical approach to identify peripheral metabolic changes and corresponding metabolic biomarkers of neurological disorders. Embodiments of the present disclosure include the use of bile acids and their derivatives as metabolic biomarkers to aid in the determination of whether a subject suffers from, or is at risk of developing, a neurological disorder, such as Alzheimer's Disease (AD). |
| FILED | Saturday, February 24, 2018 |
| APPL NO | 16/488393 |
| CURRENT CPC | Steroids C07J 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) Original (OR) Class G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293825 | Bergan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond Bergan (Portland, Oregon); Ryan Gordon (Portland, Oregon) |
| ABSTRACT | Disclosed are methods for identifying an agent of interest that alters binding or activity of a client protein to a chaperone and kits thereof. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 17/262556 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2440/14 (20130101) G01N 2500/02 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294830 | Kasthurirathne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suranga Nath Kasthurirathne (Indianapolis, Indiana); Shaun Jason Grannis (Indianapolis, Indiana) |
| ABSTRACT | Methods and systems disclosed herein relate to using machine learning to identify names from a database. In an exemplary embodiment, a name identification system comprises a database including a plurality of name pairs. The name identification system also comprises a computing device operatively coupled with the database. The computing device is configured to perform the following: extract the plurality of name pairs from the database; calculate features for each name pair from the plurality of name pairs; assign a name pair data vector to the each name pair based on the features calculated for the each name pair; separate the name pair data vectors into a training dataset and a holdout dataset; train a decision model, via machine learning, based on the training dataset; apply the decision model to the holdout dataset; and evaluate the decision model. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205765 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) Original (OR) Class G06F 40/295 (20200101) Computer Systems Based on Specific Computational Models G06N 5/003 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295193 | Harrison |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert W. Harrison (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present systems and methods may provide techniques for deterministic training of cRBMs. Embodiments may utilize least square error estimates for the hidden variables, which is computationally tractable and provides improved results. For example, in an embodiment, a computer-implemented method for machine learning may comprise generating a continuous restricted Boltzman machine model by replacing discrete valued spins in a discrete restricted Boltzman machine model with continuous values, training the continuous restricted Boltzman machine model using a training dataset using a deterministic training process having hidden variables defined using least square error estimates, and using the trained continuous restricted Boltzman machine model to recognize patterns in new data. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 17/265395 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 7/08 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295505 | Constance et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward Constance (Washington, District of Columbia); Kadir Aslan (Towson, Maryland); Enock Bonyi (Rosedale, Maryland) |
| ABSTRACT | Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204194 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/90 (20170101) G06T 2207/10024 (20130101) G06T 2207/30072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295528 | FUCHS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas FUCHS (New York, New York); David Joon HO (New York, New York) |
| ABSTRACT | Described herein are systems and methods of training models to segment images. A device may identify a training dataset. The training dataset may include images each having a region of interest. The training dataset may include first annotations. The device may train, using the training dataset, an image segmentation model having parameters to generate a corresponding first segmented images. The device may provide the first segmented images for presentation on a user interface to obtain feedback. The device may receive, via the user interface, a feedback dataset including second annotations for at least a subset of the first segmented images. Each of the second annotations may label at least a second portion of the region of interest in a corresponding image of the subset. The device may retrain, using the feedback dataset received via the user interface, the image segmentation model. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/201826 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6267 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/187 (20170101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295673 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| INVENTOR(S) | Peng Liu (Chicago, Illinois); Yang Liu (Chicago, Illinois) |
| ABSTRACT | A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341789 |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/245 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20210290593 | Jacobsen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob P.R. Jacobsen (Durham, North Carolina); Marc G. Caron (Hillsborough, North Carolina); Michael Gershon (New York, New York); Kara Margolis (New York, New York) |
| ABSTRACT | The present invention provides, inter alia, methods for treating or ameliorating a gastrointestinal (GI) condition such as constipation in a subject in need thereof, using a sustained release formulation of 5-hydroxytryptophan (5-HTP SR). A kit comprising 5-HTP SR is also provided. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 17/250350 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/405 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290664 | Ehrlich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (NEW HAVEN, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (NEW HAVEN, Connecticut) |
| INVENTOR(S) | Barbara Ehrlich (New Haven, Connecticut); Sara Rockwell (Madison, Connecticut); Jennifer Benbow (Fort Mill, South Carolina) |
| ABSTRACT | The invention provides a method of treatment comprising reducing therapy-induced adverse effects (TIAE), including chemotherapy-induced adverse effects (CIAE), such as chemotherapy-induced peripheral neuropathy (CIPN) and/or chemotherapy-induced cardiovascular adverse effects (CICAE) in a subject being treated with a CIAE-inducing anti-cancer active ingredient by co-administering to the subject a pharmaceutically effective amount of a NCS-1-protective composition. Related pharmaceutical compositions, diagnostics and screening techniques are also provided. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192185 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/20 (20130101) A61K 31/337 (20130101) A61K 31/416 (20130101) A61K 31/437 (20130101) A61K 31/5415 (20130101) A61K 33/00 (20130101) A61K 33/14 (20130101) Original (OR) Class A61K 38/57 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290781 | Chekmenev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eduard Y. Chekmenev (Troy, Michigan); Baptiste Joalland (Hamtramck, Michigan); Nuwandi M. Ariyasingha (Rochester Hills, Michigan) |
| ABSTRACT | A RASER-inducing contrast agent for magnetic resonance (MR) modalities that includes a parahydrogen addition to unsaturated molecular precursor that renders radio amplification by stimulated emission of radiation (RASER) of protons and other nuclear spins. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/202454 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290829 | Kaplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Konstantinos Tsioris (Somerville, Massachusetts); Fiorenzo G. Omenetto (Lexington, Massachusetts); Eleanor M. Pritchard (New Orleans, Louisiana) |
| ABSTRACT | A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173289 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/205 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/047 (20130101) A61L 31/125 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 37/0015 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291137 | Qing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Quan Qing (Chandler, Arizona); Ching-wei Tsao (Tempe, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising a top surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/257816 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00317 (20130101) B01J 2219/00529 (20130101) B01J 2219/00596 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00822 (20130101) B01J 2219/00853 (20130101) B01J 2219/00855 (20130101) Peptides C07K 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292393 | WESTENDORF et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Hunman Servi (Bethesda, Maryland) |
| ASSIGNEE(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Hunman Servi (Bethesda, Maryland) |
| INVENTOR(S) | Kathryn WESTENDORF (Vancouver, Canada); Stefanie ZENTELIS (Vancouver, Canada); Krithika MUTHURAMAN (Toronto, Canada); Kevin JEPSON (Vancouver, Canada); Ester FALCONER (Vancouver, Canada); John MASCOLA (Bethesda, Maryland); Barney GRAHAM (Bethesda, Maryland); Kizzmekia CORBETT (Bethesda, Maryland); Julie LEDGERWOOD (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Olubukola ABIONA (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Wing-pui KONG (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Bryan Edward JONES (San Diego, California); Denisa FOSTER (San Diego, California); Julian DAVIES (La Jolla, California); Qing CHAI (San Diego, California); Christopher Carl FRYE (Bargersville, Indiana); Ganapathy GOPALRATHNAM (Fishers, Indiana); Jörg HENDLE (San Diego, California); John Michael SAUDER (Carlsbad, California); Jeffrey Streetman BOYLES (Indianapolis, Indiana); Anna PUSTILNIK (San Diego, California) |
| ABSTRACT | Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) A61K 47/6801 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292394 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F.. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Carlisle, Massachusetts); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for antibodies useful for filovirus infections. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/135525 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 2317/76 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292482 | BOWMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORTATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CHRISTOPHER N. BOWMAN (BOULDER, Colorado); BRADY T. WORRELL (BOULDER, Colorado); GAYLA BERG LYON (MEDFORD, Massachusetts); MATTHEW K. MCBRIDE (BOULDER, Colorado); CHEN WANG (BOULDER, Colorado) |
| ABSTRACT | The present invention relates to covalent adaptable networks (CANs) having exchangeable crosslinks that are able to undergo repeated covalent bond reshuffling through photo-activation at ambient temperatures. The invention provides covalent adaptable network forming compositions as well as methods of forming, remolding and recycling the CANs of the invention. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 16/326567 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/775 (20130101) C08G 18/3876 (20130101) C08G 18/8166 (20130101) C08G 75/26 (20130101) Original (OR) Class C08G 75/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292573 | WEBSTER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NDSU RESEARCH FOUNDATION (Fargo, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean C. WEBSTER (Fargo, North Dakota); Alireza RAHIMI (N. Royalton, Ohio) |
| ABSTRACT | The invention relates to a curable coating composition comprising at least one surface-modifying amphiphilic additive and at least one siloxane-polyurethane coating composition. The invention also relates to methods of making and using the curable coating composition of the invention. The invention also relates to methods for reducing or preventing biofouling of a surface exposed to an aqueous environment comprising the use of the curable coating composition of the invention. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200442 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1675 (20130101) C09D 5/1687 (20130101) Original (OR) Class C09D 183/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292581 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brewer Science, Inc. (Rolla, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zun Chen (Springfield, Missouri); Jonathan J. Fury (Springfield, Missouri); Alec Neeson (Springfield, Missouri) |
| ABSTRACT | A copolymer of polytetrafluoroethylene and a perfluoro acid (e.g., Nafion™) is neutralized by a base to yield its corresponding salt, and a high-boiling-point compatible solvent is used as a substituting solvent, with the original, low-boiling-point solvent being removed by rotor evaporation. The resulting dispersion is screen printable, and its viscosity is controllable by adjusting its solids content. This screen-printable salt dispersion is especially useful in printed electronics applications such as sensors. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208386 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/12 (20130101) B41M 1/30 (20130101) B41M 5/0023 (20130101) B41M 5/0047 (20130101) B41M 5/0064 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 214/184 (20130101) C08F 214/262 (20130101) C08F 2810/50 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/033 (20130101) C09D 11/106 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292613 | Wilker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan James Wilker (Lafayette, Indiana); Heather Meredith Chaput (Beavercreek, Ohio) |
| ABSTRACT | Embodiments of this invention relate to adhesives, and more particularly to biomimetic heteropolymer adhesive compositions. Certain embodiments relate to biomimetic terpolymer adhesive compositions including dopamine methacrylamide, 3,4-dihydroxyphenylalanine, or 3,4-dihydroxystyrene, mimicking moieties found in marine mussel adhesive proteins. In some embodiments, elastic moduli of the adhesives are preferably selected to match the elastic moduli of the substrates to minimize stress concentrations, to increase the ductility of the adhesive-substrate system, or both. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338237 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/24 (20130101) C08F 120/14 (20130101) C08F 220/14 (20130101) C08F 220/28 (20130101) C08F 220/60 (20130101) C08F 220/286 (20200201) C08F 220/603 (20200201) C08F 2800/10 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 125/18 (20130101) C09J 133/08 (20130101) C09J 133/10 (20130101) C09J 133/12 (20130101) C09J 133/14 (20130101) C09J 133/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292718 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Kai Chen (Pasadena, California); Noah P. Dunham (Pasadena, California); Daniel J. Wackelin (Pasadena, California); Andrew Z. Zhou (Pasadena, California); Zhen Liu (Pasadena, California) |
| ABSTRACT | The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200394 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0042 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 17/04 (20130101) C12P 17/16 (20130101) Enzymes C12Y 106/02004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292737 | Brangwynne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Cliff Brangwynne (Hopewell, New Jersey); Dan Bracha (Princeton, New Jersey) |
| ABSTRACT | A system and method for reversibly controlling clustering of proteins around an engineered multivalent nucleus is disclosed. The system and method utilize clustering, which may be controlled by light activation or deactivation. The system and method enable the spatiotemporal control of protein supramolecular assemblies, including liquid-like droplets under some conditions, and solid-like gels under other conditions. The system and method can be utilized for segregating or locally concentrating desired proteins and/or RNA in cells or cell lysate, which may be useful for protein purification purposes, or for assembling single or multiple membraneless bodies within specific sub-regions of the cells. These synthetically assembled bodies may recruit both transgenic and endogenic proteins and other biomolecules, thus can be linked to affect and even trigger a plethora of cellular processes, including both physiological and pathological (e.g., protein aggregation) processes. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/335473 |
| CURRENT CPC | Peptides C07K 1/14 (20130101) C07K 2319/00 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292930 | PALUMBO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTEGRAN TECHNOLOGIES INC. (Mississauga, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | GINO PALUMBO (TORONTO, Canada); LEO MONACO (TORONTO, Canada); JONATHAN MCCREA (TORONTO, Canada); KLAUS TOMANTSCHGER (MISSISSAUGA, Canada); DAVE LIMOGES (ETOBICOKE, Canada); MICHAEL MILLS (TORONTO, Canada) |
| ABSTRACT | An apparatus and system for in-situ electropolishing and/or for in-situ electroforming a structural or functional reinforcement layer such as a sleeve of a selected metallic material on the internal surfaces of metallic tubular conduits are described. The apparatus and system can be employed on straight tubes, tube joints to different diameter tubes or face plates, tube elbows and other complex shapes encountered in piping systems. The apparatus includes components which can be independently manipulated and assembled on or near a degraded site and, after secured in place, form an electrolytic cell within the workpiece. The apparatus contains counter-electrodes which can be moved relative to the workpiece surface during the electroplating and/or electropolishing operation to provide flexibility in selecting and employing electropolishing process parameters and electroplating process parameters to design and optimize the surface roughness as well as the size, shape and properties of the electrodeposited reinforcing layer(s). |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 16/824165 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/12 (20130101) C25D 3/38 (20130101) C25D 7/04 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) Original (OR) Class C25F 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292934 | Wetzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric D. Wetzel (Baltimore, Maryland); Larry R. Holmes, JR. (Peach Bottom, Pennsylvania); Ricardo X. Rodriguez (Pembroke Pines, Florida); Patrick M. Toal, JR. (Pearl River, New York) |
| ABSTRACT | A thermoplastic filament comprising multiple polymers of differing flow temperatures in a regular geometric arrangement, and a method for producing such a filament, are described. Because of the difference in flow temperatures, there exists a temperature range at which one polymer is mechanically stable while the other is flowable. This property is extremely useful for creating thermoplastic monofilament feedstock for three-dimensionally printed parts, wherein the mechanically stable polymer enables geometric stability while the flowable polymer can fill gaps and provide strong bonding and homogenization between deposited material lines and layers. These multimaterial filaments can be produced via thermal drawing from a thermoplastic preform, which itself can be three-dimensionally printed. Furthermore, the preform can be printed with precisely controlled and complex geometries, enabling the creation of monofilament and fiber with unique decorative or functional properties. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219697 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 65/565 (20130101) B29C 66/53 (20130101) B29C 66/61 (20130101) B29C 66/5221 (20130101) B29C 66/5241 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) B29D 11/00701 (20130101) B29D 11/00721 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Manufacture, Shaping, or Supplementary Processes C03B 19/00 (20130101) C03B 37/027 (20130101) C03B 37/028 (20130101) C03B 2201/06 (20130101) C03B 2201/32 (20130101) C03B 2201/70 (20130101) C03B 2201/86 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/30 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/00 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/08 (20130101) D10B 2321/10 (20130101) D10B 2331/04 (20130101) Optical Elements, Systems, or Apparatus G02B 6/00 (20130101) G02B 6/02033 (20130101) G02B 6/02314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293490 | Huitink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| INVENTOR(S) | David Huitink (Prairie Grove, Arkansas); Ange Christian Iradukunda (Fayetteville, Arkansas) |
| ABSTRACT | A heat removal system comprising a heat sink, a plurality of fractal-fins each having a predetermined geometry; and a plurality of phase change materials each having a predetermined geometry. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338477 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/02 (20130101) F28D 20/021 (20130101) F28D 20/026 (20130101) Original (OR) Class F28D 2021/0029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293643 | Correll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Nikolaus Correll (Boulder, Colorado); Radhen Patel (Boulder, Colorado); Jacob Segil (Boulder, Colorado); John Klingner (Boulder, Colorado); Richard F. Weir (Longmont, Colorado) |
| ABSTRACT | Various embodiments of the present technology generally relate to robotics and prosthetics. More specifically, some embodiments of the present technology relate to multi-modal fingertip sensors with proximity, contact, and for localization capabilities. Various embodiments of the present technology provide for a novel multi-modal tactile sensor which comprises an infrared proximity sensor and a barometric pressure sensor embedded in an elastomer layer. Signals from both of these sensors can be fused to measure proximity (0-10 mm), contact (0N), force (0-50N) and localize impact at five spatial locations and three angles of incidence. Gaussian processes in a regression setting can be used to obtain calibrated force measurements with an R-squared value of 0.99. Supervised machine learning approaches can be used to localize the position and direction of probing with classification accuracies of 96% and 89% respectively. |
| FILED | Friday, July 05, 2019 |
| APPL NO | 17/257715 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/586 (20130101) A61F 2002/7635 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0009 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293809 | Beckley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MFB Fertility,Inc. (Erie, Colorado) |
| ASSIGNEE(S) | MFB Fertility,Inc. (Erie, Colorado) |
| INVENTOR(S) | Amy Beckley (Erie, Colorado) |
| ABSTRACT | Various aspects of the system and methods described herein rely upon the operation of lateral flow assays specially configured to evaluate a bodily fluid for at least the presence or absence of pregnanediol glucuronide at a threshold selected from the range inclusive of 1 μg/mL-10 μg/mL. The results from the lateral flow assays are optionally interpreted in association with an application operating upon a mobile device or a system for the collection, interpretation and storage of results. The interpretations are useful in accordance with facilitating diagnoses and treatments associated with medical conditions related to the generated interpretations of the lateral flow assays. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317212 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/76 (20130101) G01N 33/558 (20130101) Original (OR) Class G01N 33/689 (20130101) G01N 33/743 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294039 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeremiah Q. Williams (Dayton, Ohio); Hengky Chandrahalim (Beavercreek, Ohio) |
| ABSTRACT | A method is provided for fabricating a passive optical sensor on a tip of an optical fiber. The method includes perpendicularly cleaving a tip of an optical fiber and mounting the tip of the optical fiber in a specimen holder of a photosensitive polymer three-dimensional micromachining machine. The method includes forming a three-dimensional microscopic optical structure within the photosensitive polymer that comprises a two cavity Fabry-Perot Interferometer (FPI) having a hinged optical layer that is pivotally coupled to a suspended structure. The method includes removing an uncured portion of the photosensitive polymer using a solvent. The method includes depositing a reflective layer on a mirror surface of the hinged optical layer. The method includes positioning the pivotally hinged optical layer to a closed position with the suspended structure, aligning the mirror surface with the cleaved tip of the optical fiber. |
| FILED | Wednesday, April 21, 2021 |
| APPL NO | 17/236028 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) G02B 6/29358 (20130101) G02B 6/29359 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294088 | GREENWALD |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David GREENWALD (O'Hara, Pennsylvania) |
| ABSTRACT | An optical element support system and a method of supporting an optical element are provided. The optical element includes an optical axis, an arcuate front surface, and a back surface. The optical element support system includes an axial support system that provides axial support to the optical element in a direction parallel to the optical axis of the optical element, and further includes a lateral support system that provides lateral support to the optical element in one or more directions perpendicular to the optical axis of the optical element that is offset from a center-of-gravity of the optical element. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338356 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/02 (20130101) G02B 7/182 (20130101) G02B 23/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294748 | BOETTCHER |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arm Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthias Lothar BOETTCHER (Cambridge, United Kingdom) |
| ABSTRACT | There is provided a data processing apparatus that includes memory circuitry that provides a physical address space, which is logically divided into a plurality of memory segments and stores a plurality of accessors with associated validity indicators. Each of the accessors controls access to a region of the physical address space in dependence on at least its associated validity indicator. Tracking circuitry tracks which of the memory segments contain the accessors and invalidation circuitry responds to a request to invalidate an accessor by determining a set of equivalent accessors with reference to the tracking circuitry, and invalidating the accessor and the equivalent accessors by setting the associated validity indicator of each of the accessor and the equivalent accessors to indicate that the accessor and the equivalent accessors are invalid. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825021 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30018 (20130101) G06F 12/023 (20130101) G06F 12/0864 (20130101) G06F 12/0891 (20130101) Original (OR) Class G06F 12/1027 (20130101) G06F 12/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294897 | Stephenson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Govemment of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark M. Stephenson (New Carlisle, Ohio); Patrick Reber (Dayton, Ohio); Patrick J. Sweeney (Beavercreek, Ohio); Scott Graham (Beavercreek, Ohio) |
| ABSTRACT | An active attestation apparatus verifies at runtime the integrity of untrusted machine code of an embedded system residing in a memory device while it is being run/used with while slowing the processing time less than other methods. The apparatus uses an integrated circuit chip containing a microcontroller and a reprogrammable logic device, such as a field programmable gate array (FPGA), to implement software attestation at runtime and in less time than is typically possible with comparable attestation approaches, while not requiring any halt of the processor in the microcontroller. The reprogrammable logic device includes functionality to load an encrypted version of its configuration and operating code, perform a checksum computation, and communicate with a verifier. The checksum algorithm is preferably time optimized to execute computations in the reprogrammable logic device in the minimum possible time. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341575 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) Original (OR) Class G06F 21/602 (20130101) G06F 2221/033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294954 | Kia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Behnam Kia (Raleigh, North Carolina); William Ditto (Raleigh, North Carolina); Yaman Dalal (Raleigh, North Carolina); Ravikanth Somsole (Raleigh, North Carolina); Siva Rama Maruthi Ven Donepudi Krishna Sesha Sai (Raleigh, North Carolina); Allen R. Mendes (Raleigh, North Carolina); Akshay Parnami (Raleigh, North Carolina); Robin George (Raleigh, North Carolina) |
| ABSTRACT | A system can include a nonlinear circuit and a voltage decoder. The nonlinear circuit can perform an operation on an input voltage. The operation can be changed. A voltage decoder can be communicatively coupled to the nonlinear circuit for receiving an output voltage from the nonlinear circuit that results from the operation performed on the input voltage. The voltage decoder can compare the output voltage to a threshold voltage and determine a result of the operation. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 16/326603 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/38 (20200101) Original (OR) Class G06F 30/333 (20200101) G06F 30/337 (20200101) G06F 30/373 (20200101) G06F 2119/12 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294959 | HILLS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gage Krieger HILLS (Mill Valley, California); Max SHULAKER (Weston, Massachusetts) |
| ABSTRACT | System and methods to generate a circuit design for an integrated circuit using only allowable pairs of connected logic stages. The allowable pairs of connected logic stages are those pairs of connected logic stages with a static noise margin (SNM) above an SNM threshold. Also presented is a 16-bit microprocessor made entirely from carbon nanotube field effect transistors (CNFET) having such allowable pair of connected logic stages. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336916 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/337 (20200101) G06F 30/398 (20200101) Original (OR) Class G06F 2119/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295082 | Sikka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karan Sikka (Lawrenceville, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey); Ankan Bansal (College Park, Maryland) |
| ABSTRACT | A method, apparatus and system for zero shot object detection includes, in a semantic embedding space having embedded object class labels, training the space by embedding extracted features of bounding boxes and object class labels of labeled bounding boxes of known object classes into the space, determining regions in an image having unknown object classes on which to perform object detection as proposed bounding boxes, extracting features of the proposed bounding boxes, projecting the extracted features of the proposed bounding boxes into the space, computing a similarity measure between the projected features of the proposed bounding boxes and the embedded, extracted features of the bounding boxes of the known object classes in the space, and predicting an object class label for proposed bounding boxes by determining a nearest embedded object class label to the projected features of the proposed bounding boxes in the space based on the similarity measures. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/337093 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) G06K 9/3241 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/20 (20130101) G06T 2210/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295152 | Bouman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); High Performance Imaging LLC (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Addison Bouman (West Lafayette, Indiana); Sherman Jordan Kisner (Niskayuna, New York) |
| ABSTRACT | A computer-implemented method of latency reduction is disclosed for a digital holography optical imaging system. The method comprises receiving an incoming light field at a focal plane array of the digital holography optical imaging system, applying an interfering light field to the incoming light field at the focal plane array, and generating a holographic image based on the incoming light field and the interfering light field at the focal plane array. The method further comprises generating a sequence of phase errors based on the holographic image, generating at least one training parameter based on the sequence of phase errors, and training a neural network to revise the at least one training parameter using the sequence of phase errors, a time delay, and the at least one training parameter. The method further comprises predicting a future phase error for a future holographic image based on the revised training parameter. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153659 |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0443 (20130101) G03H 2001/0445 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295166 | Rouhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| INVENTOR(S) | Bita Darvish Rouhani (San Diego, California); Azalia Mirhoseini (Houston, Texas); Farinaz Koushanfar (San Diego, California) |
| ABSTRACT | A system may include a processor and a memory. The memory may include program code that provides operations when executed by the processor. The operations may include: partitioning, based at least on a resource constraint of a platform, a global machine learning model into a plurality of local machine learning models; transforming training data to at least conform to the resource constraint of the platform; and training the global machine learning model by at least processing, at the platform, the transformed training data with a first of the plurality of local machine learning models. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 16/077395 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Original (OR) Class G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295505 | Constance et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward Constance (Washington, District of Columbia); Kadir Aslan (Towson, Maryland); Enock Bonyi (Rosedale, Maryland) |
| ABSTRACT | Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204194 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/90 (20170101) G06T 2207/10024 (20130101) G06T 2207/30072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295861 | BALASUBRAMANIYAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vijay BALASUBRAMANIYAN (Atlanta, Georgia); Mustaque AHAMAD (Atlanta, Georgia); Patrick Gerard TRAYNOR (Decatur, Georgia); Michael Thomas HUNTER (Atlanta, Georgia); Aamir POONAWALLA (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338523 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/162 (20130101) G06F 16/22 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 25/51 (20130101) Original (OR) Class Telephonic Communication H04M 3/2281 (20130101) H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296107 | Newsome et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Graham Asher Newsome (Riverdale, Maryland); Kevin John Johnson (Odenton, Maryland); Michael Paul Malito (Washington, District of Columbia) |
| ABSTRACT | A method of transferring neutral gaseous material includes the steps of passing heated gas through flow tube in a central gas stream; and permeating a chemical dopant inward to the central gas stream through walls of the flow tube. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207336 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0422 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296524 | Jernigan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenn G. Jernigan (Waldorf, Maryland); Mark E. Twigg (Falls Church, Virginia); Nadeemullah A. Mahadik (Springfield, Virginia); Jill A. Nolde (Takoma Park, Maryland) |
| ABSTRACT | A method of growing fully relaxed SiGeSn buffer layers on Si substrates to produce virtual substrates for the epitaxial growth of high quality GeSn films suitable for high performance infrared (IR) optoelectronic device technology directly integrated on silicon. Growing the SiGeSn virtual substrate uses a precisely decreasing growth temperature and Si flux and a precisely increasing Ge and Sn flux. The virtual substrates may have a slightly larger lattice constant than that of the target GeSn alloy to impose a precise degree of tensile strain resulting in a direct band gap for the target GeSn alloy. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/209133 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/025 (20130101) C30B 29/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0312 (20130101) H01L 31/1812 (20130101) Original (OR) Class H01L 31/03921 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296602 | Rand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barry P. Rand (Princeton, New Jersey); Lianfeng Zhao (Jersey City, New Jersey) |
| ABSTRACT | Provided is a thin film semiconductor device that exploits excitonic characteristics of various organic semiconductor materials. The device may include an anode (120), a cathode (170), and a donor-acceptor heterojunction (150) disposed between the anode and the cathode. The donor-acceptor heterojunction may further include an acceptor material (404) having a highest occupied molecular orbital (HOMO) and a lowest unoccupied molecular orbital (LUMO), and a donor material (402) comprising a hybrid organic-inorganic metal halide perovskite semiconductor. Other embodiments are disclosed and additional embodiments are also possible. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 17/264037 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/001 (20130101) H01L 51/0003 (20130101) H01L 51/0026 (20130101) H01L 51/0077 (20130101) H01L 51/426 (20130101) Original (OR) Class H01L 51/4213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296622 | Alivisatos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Armand Paul Alivisatos (Berkeley, California); Farnaz Niroui (Cambridge, Massachusetts); Vida Jamali (Menlo Park, California); Matteo Pasquali (Houston, Texas) |
| ABSTRACT | In various embodiments a light emitting fiber is provided as well as articles of manufacture comprising one or more light emitting fibers. In certain embodiments the light emitting fiber comprises a conductive carbon nanotube fiber; an emissive layer surrounding the carbon nanotube fiber; and a conductive outer layer disposed outside the emissive layer. In certain embodiments the light emitting fiber comprises a hole transport layer disposed between the carbon nanotube fiber and the emissive layer. In certain embodiments the light emitting fiber comprise a hole injection layer disposed between the nanotube fiber and the hole transport layer. In certain embodiments the light emitting fiber comprises an electron transport layer and, optionally an electron injection layer. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 17/265510 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/06 (20130101) C09K 11/08 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 11/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0021 (20130101) H01L 51/0035 (20130101) H01L 51/0037 (20130101) H01L 51/0049 (20130101) H01L 51/56 (20130101) H01L 51/0077 (20130101) H01L 51/502 (20130101) H01L 51/5032 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5088 (20130101) H01L 51/5092 (20130101) H01L 51/5206 (20130101) H01L 51/5253 (20130101) H01L 51/5287 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/60 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296675 | Gervasio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dominic Francis Gervasio (Tucson, Arizona); Peiwen Li (Tucson, Arizona) |
| ABSTRACT | A fuel cell stack comprising one or more high temperature membrane electrode assemblies (MEAs) and a bipolar plate comprising a liquid cooling chamber and gas flow channels; the use thereof, and the preparation thereof. The invention also encompasses an electrical generating system. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221690 |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 43/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/8605 (20130101) H01M 8/0258 (20130101) H01M 8/0267 (20130101) H01M 8/1213 (20130101) Original (OR) Class H01M 8/04029 (20130101) H01M 8/04074 (20130101) H01M 2008/1095 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296757 | Timberlake |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Garrett L. Timberlake (Virginia Beach, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Garrett L. Timberlake (Virginia Beach, Virginia) |
| ABSTRACT | A pedestal is provided for mounting a portable antenna onto a platform. The pedestal includes a base, a horn and a prong composed of three-dimensionally printable composite resin. The base includes an outer tube having a pair of axially distributed outer holes. The horn includes an inner tube for insertion into the outer tube and an inverted pyramid that connects to the inner tube. The inner tube includes at least three axially distributed inner holes. The prong has two probes that insert into the outer holes and two of the inner holes to secure the horn to the base. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853654 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Antennas, i.e Radio Aerials H01Q 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296856 | Kaneda |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yushi Kaneda (Tucson, Arizona) |
| ABSTRACT | Methods, devices and systems for improving single-frequency operation of diode lasers are described. One such method includes ramping up an operational current of a diode laser for a first predetermined number of steps, and measuring an associated current value indicative of optical power within the laser diode for each of the first predetermined number of steps. Next, operational current of the diode laser is ramped down for a second predetermined number of steps, and an associated current value indicative of optical power within the laser diode is measured for each of the second predetermined number of steps. Using the measured data current values at which a mode hop or a multimode operation is likely to occur are identified, and a contiguous range of operating currents that is devoid of identified likely mode hops or multimode regions of operation is determined as the operating current range of the diode laser. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 17/263686 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/024 (20130101) H01S 5/0092 (20130101) H01S 5/141 (20130101) H01S 5/0617 (20130101) Original (OR) Class H01S 5/0653 (20130101) H01S 5/06808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210297498 | Divakaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ajay Divakaran (Monmouth Junction, New Jersey); Karan Sikka (Lawrenceville, New Jersey); Arijit Ray (Princeton, New Jersey); Xiao Lin (Princeton, New Jersey); Yi Yao (Princeton, New Jersey) |
| ABSTRACT | A method, apparatus and system for determining user-content associations for determining and providing user-preferred content using multimodal embeddings include creating an embedding space for multimodal content by creating a first modality vector representation of the multimodal content having a first modality, creating a second modality vector representation of the multimodal content having a second modality, creating a user vector representation, as a third modality, for each user associated with at least a portion of the multimodal content, and embedding the first and the second modality vector representations and the user vector representations in the common embedding space using at least a mixture of loss functions for each modality pair of the first, the at least second and the third modalities that pushes closer co-occurring pairs of multimodal content. Embodiments can further include generating content using determined attributes of a message to be conveyed and features of the user-preferred content. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/191698 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/22 (20130101) H04L 67/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20210289716 | Lokdarshi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ansul Lokdarshi (Knoxville, Tennessee) |
| ABSTRACT | An enclosure for maintaining biological matter therein under controlled conditions can include a main body, which has an interior space and a door through which the interior space is accessible, one or more light emitter panels that illuminate the interior space, a base that receives the main body thereon and comprises a cooling system. The cooling system can have a container, a fluid inlet for introducing a fluid into the container, and a fluid outlet for removing the fluid from the container; and a top section that is removably attached to a top surface of the main body. Such an enclosure is capable of maintaining a temperature within the interior space between about 14° C. and about 30° C. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/075445 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/045 (20130101) A01G 9/246 (20130101) Original (OR) Class A01G 9/249 (20190501) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/02 (20130101) C12M 29/20 (20130101) C12M 31/10 (20130101) C12M 41/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290074 | ERTIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emre ERTIN (Columbus, Ohio); William T. ABRAHAM (Columbus, Ohio) |
| ABSTRACT | Various examples related to mobile bodily monitoring using ultra-wideband radar are provided. In one example, a method for determining a bodily characteristic includes collecting sets of reflected backscatter data for a sequence of ultra-wideband (UWB) pulses transmitted via an UWB sensor, and a corresponding calibration measurement from a calibration channel; determining reflection coefficients for each tissue interface based on the sets of reflected backscatter data; and determining a fluid level content of the lung tissue based upon the reflection coefficients. The reflection coefficients can be determined from reflection profiles based upon the reflected backscatter data for that sequence of UWB pulses and the corresponding calibration measurement. The UWB sensor can include an array of transmit (TX) and receive (RX) antenna pairs positioned on a body of a user. The reflection profile can be associated with a model of tissue layers in the body between the UWB sensor and lung tissue. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 17/260827 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0205 (20130101) Original (OR) Class A61B 5/0507 (20130101) A61B 5/0537 (20130101) A61B 5/6833 (20130101) A61B 2560/0223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290431 | Kulstad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Cooling Therapy, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Kulstad (Chicago, Illinois); Patrick Shanley (Chicago, Illinois) |
| ABSTRACT | Methods, devices, and systems for temperature management of a pediatric patient in a perioperative environment are disclosed. Methods, devices, and systems for maintaining normothermia in a pediatric patient in a perioperative environment are disclosed. The use of esophageal heat transfer devices for perioperative temperature management and/or maintenance of normothermia in a pediatric patient is disclosed. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339514 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/12 (20130101) Original (OR) Class A61F 2007/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290770 | Jeffries et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric M. Jeffries (West New York, New Jersey); Yadong Wang (Bradford Woods, Pennsylvania) |
| ABSTRACT | Provided herein are coacervate compositions including cytokines, and methods of making and using the same. The coacervate can be formed by the mixing of an active agent, such as a drug or protein with the polyanion, such as heparin or heparan sulfate, and a custom-made polycation (e.g., PEAD or PELD). The coacervates can be used in the treatment of diseases and disorders where targeted treatment is desired, for example in treatment of cancers. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 31/727 (20130101) A61K 38/18 (20130101) A61K 38/20 (20130101) A61K 38/21 (20130101) A61K 38/208 (20130101) A61K 38/1825 (20130101) A61K 38/2066 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 47/58 (20170801) Original (OR) Class A61K 47/61 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290781 | Chekmenev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eduard Y. Chekmenev (Troy, Michigan); Baptiste Joalland (Hamtramck, Michigan); Nuwandi M. Ariyasingha (Rochester Hills, Michigan) |
| ABSTRACT | A RASER-inducing contrast agent for magnetic resonance (MR) modalities that includes a parahydrogen addition to unsaturated molecular precursor that renders radio amplification by stimulated emission of radiation (RASER) of protons and other nuclear spins. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/202454 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290787 | MAGDA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LUMIPHORE, INC. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darren MAGDA (San Leandro, California); David TATUM (Berkeley, California); Nathaniel G. BUTLIN (Pacifica, California) |
| ABSTRACT | The invention relates to chemical compounds and complexes that can be used in therapeutic and diagnostic applications. In various embodiments, the invention described herein pertains to the diagnosis, imaging, and/or treatment of pathogenic cell populations. In particular, the invention described herein pertains to the diagnosis, imaging, and/or treatment of diseases caused by PSMA express-ing cells, such as prostate cancer cells, using compounds capable of targeting PSMA expressing cells. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 17/253550 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 49/0056 (20130101) A61K 51/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291137 | Qing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Quan Qing (Chandler, Arizona); Ching-wei Tsao (Tempe, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising a top surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/257816 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00317 (20130101) B01J 2219/00529 (20130101) B01J 2219/00596 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00822 (20130101) B01J 2219/00853 (20130101) B01J 2219/00855 (20130101) Peptides C07K 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291138 | FAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Qi Hua FAN (Okemos, Michigan); Martin E. TOOMAJIAN (Brighton, Michigan); Thomas SCHUELKE (Pinckney, Michigan) |
| ABSTRACT | A vertically oriented plasma reactor is provided. In another aspect, a plasma reactor includes a vertically elongated vacuum chamber, a wall internally projecting within a middle section of the housing, magnets, electrodes and a radio frequency source. A further aspect employs a workpiece-entry port and an opposite workpiece material-exit port, with one located adjacent a top end and the other adjacent a bottom end of a vertically elongated reactor housing or vacuum chamber. Yet another aspect employs a moving or falling-bed plasma reactor for use in activating biochar material. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 17/258881 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/006 (20130101) B01J 19/088 (20130101) Original (OR) Class B01J 20/20 (20130101) B01J 20/3416 (20130101) B01J 2219/0894 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/366 (20170801) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/466 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291185 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Mohammad Aghaamoo (Irvine, California); Xuan Li (Irvine, California); Neha Garg (Irvine, California); Yu-Hsi Chen (Irvine, California) |
| ABSTRACT | The present invention features the use of cavity acoustic transducers (CATs) to apply mechanical stimuli on cells. CATs utilize the generated acoustic microstreaming vortices to trap cells and apply tunable shear on them. The present invention may use such a portable, automated, and high throughput device for cell transfection. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340581 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502769 (20130101) B01L 2200/18 (20130101) B01L 2200/0668 (20130101) B01L 2300/0645 (20130101) B01L 2300/0809 (20130101) B01L 2400/0415 (20130101) B01L 2400/0436 (20130101) B01L 2400/0439 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291355 | LERNER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Northen Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Forest LERNER (Flagstaff, Arizona); Greg OREKHOV (Flagstaf, Arizona); Jason LUQUE (Flagstaff, Arizona) |
| ABSTRACT | A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207317 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/5061 (20130101) A61H 2201/5071 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292482 | BOWMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORTATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | CHRISTOPHER N. BOWMAN (BOULDER, Colorado); BRADY T. WORRELL (BOULDER, Colorado); GAYLA BERG LYON (MEDFORD, Massachusetts); MATTHEW K. MCBRIDE (BOULDER, Colorado); CHEN WANG (BOULDER, Colorado) |
| ABSTRACT | The present invention relates to covalent adaptable networks (CANs) having exchangeable crosslinks that are able to undergo repeated covalent bond reshuffling through photo-activation at ambient temperatures. The invention provides covalent adaptable network forming compositions as well as methods of forming, remolding and recycling the CANs of the invention. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 16/326567 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/775 (20130101) C08G 18/3876 (20130101) C08G 18/8166 (20130101) C08G 75/26 (20130101) Original (OR) Class C08G 75/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292489 | Bellan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leon M. Bellan (Nashville, Tennessee); John Rector (Nashville, Tennessee) |
| ABSTRACT | Provided arm biocompatible polymer compositions, and methods of printing such polymer compositions using a fused deposition modelling printer to form a solid scaffold. In particular, the disclosed compositions may include a thermoresponsive polymer, and the printed scaffold may be used as a sacrificial template providing a three-dimensional vascular structure upon temperature-dependent disintegration. The present compositions and methods may be particularly useful for engineering thick tissues. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 17/260979 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 218/08 (20130101) C08F 226/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3322 (20130101) C08G 81/024 (20130101) Original (OR) Class C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292490 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Chueh-Yu Wu (Los Angeles, California) |
| ABSTRACT | A method of forming three-dimensional shaped microparticles in a microfluidic device includes flowing a mixture of a monomer and photoinitiator in a microfluidic channel having a plurality of pillars disposed therein to define a flow stream having a pre-defined shape and temporarily stopping the same. One or more portions of the flow stream are polymerized by passing polymerizing light through one or more masks and onto the flow stream, the polymerization process forming a plurality of three-dimensional shaped microparticles. The three-dimensional shape of the microparticle may be geometrically complex by using non-rectangular 2D orthogonal shapes for the flow and/or masked light source. The microparticles may include protected regions on which cells can be adhered to and protected from shear forces. The flow stream is restarted to flush out the newly formed microparticles and prepare the device for the next cycle of particle formation. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/340926 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292512 | Jia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Li Jia (Hudson, Ohio); Xuesong Yan (Cuyahoga Falls, None); Gary Hamed (Cuyahoga Falls, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Li Jia (Hudson, Ohio); Xuesong Yan (Cuyahoga Falls, None); Gary Hamed (Cuyahoga Falls, Ohio) |
| ABSTRACT | A vulcanizable rubber composition is includes a silica filler and a substituted catechol moiety. The substituted catechol moiety having a catechol end group with an organic substituent at the 3 or 4 position of the catechol ring, the organic substituent including a hydrocarbon moiety bound to the catechol ring and having at least 2 carbons. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/348266 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) Original (OR) Class C08K 5/13 (20130101) C08K 5/372 (20130101) C08K 9/04 (20130101) Compositions of Macromolecular Compounds C08L 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292574 | HARDIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Showa Denko Materials Co., Ltd. (Tokyo, Japan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian E. HARDIN (San Carlos, California); Fillarry SUSANTO (Alameda, California); Dhea SUSENO (Oakland, California); Daniel J. HELLEBUSCH (Oakland, California); Craig H. PETERS (Belmont, California) |
| ABSTRACT | Intercalation pastes for use with semiconductor devices are disclosed. The pastes contain precious metal particles, intercalating particles, organic vehicle, and metal-based additives (MBAs). MBAs can be used to improve the material properties of metal particle layers. Specific formulations have been developed to be screen-printed directly onto a dried metal particle layer and fired to make a fired multilayer stack. The fired multilayer stack can be tailored to create a solderable surface, high mechanical strength, and low contact resistance. In some embodiments, the fired multilayer stack can etch through a dielectric layer to improve adhesion to a substrate. Such pastes can be used to increase the efficiency of silicon solar cells, specifically multi- and mono-crystalline silicon back-surface field (BSF), and passivated emitter and rear contact (PERC) photovoltaic cells. Other applications include integrated circuits and more broadly, electronic devices. |
| FILED | Thursday, July 04, 2019 |
| APPL NO | 17/257856 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292718 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Kai Chen (Pasadena, California); Noah P. Dunham (Pasadena, California); Daniel J. Wackelin (Pasadena, California); Andrew Z. Zhou (Pasadena, California); Zhen Liu (Pasadena, California) |
| ABSTRACT | The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200394 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0042 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 17/04 (20130101) C12P 17/16 (20130101) Enzymes C12Y 106/02004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292720 | Pfleger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Jose HERNANDEZ-LOZADA (Jena, Germany); Costas MARANAS (State College, Pennsylvania); Matthew GRISEWOOD (Mountaintop, Pennsylvania) |
| ABSTRACT | Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ. ID. NO: 1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, M141, E142, Y145, and L146, gene constructs encoding and configured to express the mutated thioesterases in a transformed host cell, and host cells transformed to contain the gene constructs. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332186 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292784 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Ross D. Jones (Cambridge, Massachusetts); Breanna E. DiAndreth (Cambridge, Massachusetts); Domitilla Del Vecchio (Cambridge, Massachusetts); Yili Qian (Madison, Wisconsin) |
| ABSTRACT | The present disclosure, at least in part, relates to an engineered incoherent feed forward loop (iFFL) comprising a first transcription unit encoding an endoribonuclease and a second transcription unit encoding an output molecule and an endoribonuclease target site located in the 5′ UTR of the output molecule coding sequence. The engineered iFFL, at least in part, can be used for sustained expression of an output molecule despite of transcription resource disturbance in a given environment. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153276 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292805 | Pastore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vito Paolo Pastore (Genova, Italy); Simone Bianco (San Francisco, California) |
| ABSTRACT | A system and method that identify and classify unknown microorganisms and/or known microorganisms with anomalies are provided. The system and method comprise processing images of microorganisms from an aquatic environment; extracting features from the processed images; an unsupervised partitioning algorithm for identifying and classifying known microorganisms in the aquatic environment based upon the extracted features; and a supervised classifier neural network that is trained with the unsupervised partitioning algorithm and identifies and classifies unknown microorganisms and/or known microorganisms with anomalies. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 16/823149 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00127 (20130101) G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292929 | ZHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei ZHAN (Auburn, Alabama); MD. Shamim IQBAL (Auburn, Alabama) |
| ABSTRACT | Described herein are methods for the surface deposition of polyionic species on a substrate surface. This deposition process can be triggered facilely by oxidizing organometallic species present on the surface of the substrate. This approach is quite general, affording quantitative deposition of polyionic species with a wide range of chemical identities (e.g., synthetic polymers, peptides and DNA) and molecular weights. This approach is in addition suitable for surface deposition of several types of functional materials, including proteins (antibodies), nanomaterials, colloids, lipid vesicles, among others. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997268 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/04 (20130101) Original (OR) Class C25D 13/12 (20130101) C25D 13/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293706 | Tropp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joshua Tropp (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Tropp (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
| ABSTRACT | The methods disclosed utilize π-conjugated polymers (CPs) as sensors for various analytes through the inner filter effect (IFE). Further, the methods utilize CPs with controlled optical properties for targeting sensing applications and operates through a novel IFE-based method, providing sensitive and selective sensors that operate in complex environments. The methods further provide calibration standards for the identification of similar and structurally distinct target analytes, where the analyte is a small molecule, macromolecule, and/or biological organism of interest. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/139707 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/645 (20130101) Original (OR) Class Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/70 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293741 | Westerhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Sergio Garcia-Segura (Tempe, Arizona); Shahnawaz Sinha (Chandler, Arizona); Rishabh Bansal (Tempe, Arizona); Rafael Verduzco (Houston, Texas); Michael S. Wong (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Sergio Garcia-Segura (Tempe, Arizona); Shahnawaz Sinha (Chandler, Arizona); Rishabh Bansal (Tempe, Arizona); Rafael Verduzco (Houston, Texas); Michael S. Wong (Houston, Texas) |
| ABSTRACT | An electrode includes an electrically conductive substrate with a coating containing boron-doped diamond (BDD) nanoparticles. Fabricating the electrode can include dispersing BDD nanoparticles in a solvent to yield a suspension, coating a conductive substrate with the suspension, and drying the suspension to yield the electrode. In some cases, fabricating the electrode includes combining BDD nanoparticles with a polymeric resin precursor to yield a mixture including a metal oxide, coating a conductive substrate with the mixture to yield a coated substrate, and calcining the coated substrate to yield a metal oxide coating including BDD nanoparticles. In certain cases, fabricating the electrode includes combining powdered activated carbon with polymeric linkers to yield a polymeric precursor solution, combining BDD nanoparticles with the polymeric precursor solution to yield a mixture, coating a conductive substrate with the mixture to yield a coated substrate, and crosslinking the polymeric linkers to yield the electrode. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206935 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/46109 (20130101) C02F 2001/46147 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293782 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George Guikai Wu (Laguna Hills, California); Yonglei Shang (Laguna Hills, California) |
| ABSTRACT | Methods and systems for performing assays in compartmentalized nano-volumes to screen for functional bispecific or multispecific biologics, including: providing a plurality of at least two distinct types of cells, wherein two or more first-type cells are engineered to express substantially a single genetic-variant per cell for a bispecific or multispecific biologic in a secreted form, wherein two or more second-type cells are selected or engineered to produce a positive reporter molecule signal that is triggered by a functional variant of the said biologic expressed by a first-type cell; providing a plurality of compartmentalized nano-volumes, wherein two or more nano-volumes are each provided with substantially one first-type cell, and one or more second-type cell(s); incubating the said nano-volumes over a period of time to allow the expression and secretion of the said biologics inside the said nano-volumes; collecting data representing the positive reporter molecule signal triggered by secreted biologics inside the said nano-volumes, and recovering cells from the nano-volumes with the positive reporter molecule signal and extracting the genetic information representing respective functional variants of the biologics. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221688 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293842 | VERMA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vishal VERMA (Savoy, Illinois); Haoran YU (Urbana, Illinois); Joseph PUTHUSSERY (Champaign, Illinois) |
| ABSTRACT | Disclosed herein are instruments and related methods for measuring oxidative potential (OP) in airborne particulates, particularly PM2.5. The instrument is formed from three main components: a sample injector, a sample incubator and a measurement system. The instrument provides an automatic measure of five OP endpoints in a relatively rapid time frame of less than 3 hours. In this manner, additional parameters beyond the gross particle concentration or mass per unit volume is obtained, including the biologically-relevant OP associated with PM2.5. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204158 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/567 (20130101) B01L 7/00 (20130101) B01L 2200/026 (20130101) B01L 2200/0605 (20130101) B01L 2300/18 (20130101) B01L 2400/0403 (20130101) B01L 2400/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/6428 (20130101) G01N 35/1016 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295174 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mi ZHANG (Okemos, Michigan); Biyi FANG (Lansing, Michigan); Xiao ZENG (Lansing, Michigan) |
| ABSTRACT | Systems and methods are disclosed which allow mobile devices, and other resource constrained applications, to more efficiently and effectively utilize deep learning neural networks using only (or primarily) local resources. These systems and methods take the dynamics of runtime resources into account to enable resource-aware, multi-tenant on-device deep learning for artificial intelligence functions for use in tasks like mobile vision systems. The multi-capacity framework enables deep learning models to offer flexible resource-accuracy trade-offs and other similar balancing of performance and resources consumed. At runtime, various systems disclosed herein may dynamically select the optimal resource-accuracy trade-off for each deep learning model to fit the model's resource demand to the system's available runtime resources and the needs of the task being performed by the model. In doing so, systems and methods disclosed herein can efficiently utilize the limited resources in mobile systems to maximize performance of multiple concurrently running neural network-based applications. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 17/267467 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00711 (20130101) G06K 9/00979 (20130101) G06K 9/6227 (20130101) G06K 9/6257 (20130101) Computer Systems Based on Specific Computational Models G06N 3/10 (20130101) Original (OR) Class G06N 3/082 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295565 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Song Zhang (West Lafayette, Indiana); Tyler Bell (Lafayette, Indiana) |
| ABSTRACT | A method for generating encoded depth data includes receiving digital fringe projection (DFP) data corresponding to a three-dimensional structure of a physical object, and generating first and second fringe encodings for a first predetermined wavelength based on the DFP data at a first coordinate. The method further includes generating third and fourth fringe encodings for a second predetermined wavelength based on the DFP data at the first coordinate, the second wavelength being longer than the first wavelength, and generating a combined fringe encoding based on the third fringe encoding and the fourth fringe encoding. The method further includes storing the first, second, and combined fringe encoding data in a pixel of two-dimensional image data at a pixel coordinate in the two-dimensional image data corresponding to the first coordinate. |
| FILED | Sunday, June 06, 2021 |
| APPL NO | 17/340081 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/90 (20170101) G06T 9/00 (20130101) Original (OR) Class G06T 2207/10024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295594 | SINHA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (WEST LAFAYETTE, India) |
| ASSIGNEE(S) | |
| INVENTOR(S) | AYAN TUHINENDU SINHA (WEST LAFAYETTE, Indiana); KARTHIK RAMANI (WEST LAFAYETTE, Indiana) |
| ABSTRACT | A method using a two-dimensional (2D) image representation of three-dimensional (3D) geometric objects in a machine learning framework has been developed. The method includes generating a single 2D geometry image corresponding to a 3D object model, and providing the single geometry image as input to a shape analysis task to enable shape analysis of the 3D object model based only on information encoded in the single 2D geometry image in the machine learning framework. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 16/338881 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 15/10 (20130101) G06T 17/00 (20130101) Original (OR) Class G06T 2215/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296124 | Gagnon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jarod C. Gagnon (Finksburg, Maryland); Michael J. Presley (Silver Spring, Maryland); Steven M. Storck (Catonsville, Maryland); Jeffrey P. Maranchi (Clarksburg, Maryland); Korine A. Ohiri (Laurel, Maryland); Scott A. Shuler (Baltimore, Maryland) |
| ABSTRACT | A method for printing a semiconductor material includes depositing a molten metal onto a substrate in an enclosed chamber to form a trace having a maximum height of 15 micrometers and/or a maximum width of 25 micrometers to 10 millimeters and/or a thin film having a maximum height of 15 micrometers. The method further includes reacting the molten metal with a gas phase species in the enclosed chamber to form the semiconductor material. The depositing the molten metal includes depositing a metal composition including the molten metal and an etchant or depositing the etchant separate from the molten metal in the enclosed chamber. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338997 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02554 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296561 | NARAYAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagdish NARAYAN (Raleigh, North Carolina) |
| ABSTRACT | Certain embodiments involve processes or systems for creating various high-temperature superconductive structures or materials. For example, a method can involve depositing a first layer of boron and a second layer of un-doped amorphous carbon on a substrate. The un-doped amorphous carbon is ferromagnetic. The first layer of boron and the second layer of un-doped amorphous carbon are melted by a laser pulse to form a melted boron-doped amorphous carbon. The melted boron-doped amorphous carbon is quenched to create a quenched boron-doped amorphous carbon that is diamagnetic and superconducting. The quenched melted boron-doped amorphous carbon includes a mixture of sp3 bonded carbon atoms and sp2 bonded carbon atoms and a superconducting transition temperature of the quenched boron-doped amorphous carbon is much higher than diamond and increases based on a boron concentration. Undoped Q-carbon is ferromagnetic with Curie temperature above 500K. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 16/614686 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/56 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/12 (20130101) H01L 39/249 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296773 | BANIYA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat BANIYA (Tucson, Arizona); Kathleen L. MELDE (Tucson, Arizona) |
| ABSTRACT | A multichip system includes a plurality of processor chips each having one or more cores and a plurality of antenna module for establishing interchip wireless communication. Each antenna module is disposed on a chip. At least one antenna module includes an antenna element array and a Butler matrix. The antenna element array includes n circular patch antenna elements for 360° end-fire scanning, where n is equal to 4 or a multiple thereof. The Butler matrix has n/4 submatrices. Each submatrix include two input 90° hybrids each having two outputs and two inputs for selectively receiving signals from a transceiver. The Butler matrix also includes two output 90° hybrids each having two outputs and two inputs. The two inputs of each output 90° hybrid are coupled to an output of different ones of the input 90° hybrids. Each output of the output 90° hybrids are coupled to a different antenna element. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 17/260808 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/2283 (20130101) H01Q 3/40 (20130101) Original (OR) Class H01Q 21/065 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 1/0243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296946 | KRISHNASAMY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jayaraman KRISHNASAMY (Boxborough, Massachusetts); Martin Hosek (Salem, New Hampshire); Dennis Poole (East Derry, New Hampshire) |
| ABSTRACT | An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/330707 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/126 (20130101) Gearing F16H 25/20 (20130101) F16H 2025/2081 (20130101) Dynamo-electric Machines H02K 1/146 (20130101) Original (OR) Class H02K 1/278 (20130101) H02K 7/06 (20130101) H02K 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296983 | Rentmeister et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan S. Rentmeister (Norwich, Vermont); Jason T. Stauth (Hanover, New Hampshire) |
| ABSTRACT | A method for controlling a hybrid switched capacitor (SC) converter includes (a) generating control signals for controlling switching devices of the hybrid SC converter, in a manner which regulates one or more parameters of the hybrid SC converter, (b) detecting flying capacitor voltage imbalance in the hybrid SC converter, and (c) in response to detecting flying capacitor voltage imbalance in the hybrid SC converter, generating the control signals in a manner which varies switching state duration of the hybrid SC converter, to move flying capacitor voltage towards balance. |
| FILED | Saturday, March 20, 2021 |
| APPL NO | 17/207670 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/16538 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0025 (20210501) H02M 3/07 (20130101) Original (OR) Class H02M 3/1584 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210297098 | Haque et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tanbir Haque (Jackson Heights, New York); Peter R. Kinget (Summit, New Jersey); Matthew W. Bajor (Bayonne, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tanbir Haque (Jackson Heights, New York); Peter R. Kinget (Summit, New Jersey); Matthew W. Bajor (Bayonne, New Jersey) |
| ABSTRACT | Circuits for identifying interferers using compressed-sampling, comprising: a low noise amplifier (LNA); a passive mixer having a first input coupled to an output of the LNA; a local oscillator (LO) source having an output coupled to a second input of the passive mixer; a low pass filter having an input coupled to an output of the passive mixer; an analog-to-digital converter (ADC) having an input coupled to the output of the low pass filter; a digital baseband (DBB) circuit having an input coupled to an output of the ADC; and a compression-sampling digital-signal-processor (DSP) having an input coupled to the output of the DBB circuit, wherein the compression-sampling DSP is configured to output identifiers of frequency locations of interferers, wherein, in a first mode, the LO source outputs a modulated LO signal that is formed by modulating an LO signal with a pseudo-random sequence. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 16/331086 |
| CURRENT CPC | Transmission H04B 1/10 (20130101) Original (OR) Class H04B 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210297480 | Shi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Yuan Shi (Wayne, Pennsylvania) |
| ABSTRACT | A system for network-scale parallel computing comprises a set of computer-readable instructions implementing the steps of executing a computational process from at least one client node by communicating via a content addressable service network implemented using the Tuple Space abstraction, data parallel semantics and Unidirectional Virtual Ring architecture, with any number of service computers, networks and storage to deliver lossless, non-stop services. A network-scale distributed storage system, an enhanced DNS system, a network-scale database system and a network-scale hybrid transactional analytical processing systems are also described. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/348899 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 61/1511 (20130101) H04L 67/1034 (20130101) Original (OR) Class H04L 69/14 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20210291153 | Lee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novomer, Inc. (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Han Lee (Chicago, Illinois) |
| ABSTRACT | The present disclosure provides novel methods of making aluminum complexes with utility for promoting epoxide carbonylation reactions. Methods include reacting neutral metal carbonyl compounds with alkylaluminum complexes. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192452 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/183 (20130101) Original (OR) Class B01J 31/1815 (20130101) B01J 31/2243 (20130101) B01J 2231/321 (20130101) B01J 2531/025 (20130101) B01J 2531/31 (20130101) B01J 2531/0205 (20130101) B01J 2531/0252 (20130101) B01J 2531/845 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210291267 | HUNYADI MURPH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SIMONA E. HUNYADI MURPH (NORTH AUGUSTA, South Carolina); HENRY T. SESSIONS (AIKEN, South Carolina) |
| ABSTRACT | Vehicle structural components and additive manufacturing methods for forming the components are described. The structural components incorporate hydrogen storage materials for use in conjunction with hydrogen fuel cells in electric-powered vehicles such as unmanned aerial vehicles. The hydrogen storage materials can be in the form of a 3D printed metal foam that includes a metal hydride and an inert structural metal. The material can exhibit a very low weight density able to store hydrogen in a low pressure solid-state form at a high energy density. The structural components that carry the hydrogen storage materials can be exchangeable components of a vehicle, and the vehicle can be refueled by merely exchanging an exhausted component for a replacement component that is fully-charged with hydrogen. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 16/822634 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1125 (20130101) Original (OR) Class B22F 2003/1056 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292173 | Bayko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (, None) |
| INVENTOR(S) | Dmitriy Pavlovich Bayko (Tucson, Arizona); Steven Kmiec (Ames, Iowa); Steve W. Martin (Ames, Iowa) |
| ABSTRACT | A method is provided for making high quality silicon sulfide having 4N (99.99% by weight) or better purity. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 16/974249 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/00 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/61 (20130101) C01P 2006/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292258 | Marshall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); FORGE NANO (Louisville, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher L. Marshall (Naperville, Illinois); Zheng Lu (Bolingbrook, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Christopher Nicholas (Evanston, Illinois); Paul T. Barger (Arlington Heights, Illinois); Leigh Abrams (Chicago, Illinois); Arrelaine Dameron (Boulder, Colorado); Ryon W. Tracy (Westminster, Colorado) |
| ABSTRACT | Provided herein is an alkane dehydrogenation catalyst, a method of manufacturing an alkane dehydrogenation catalyst, and a method of converting alkanes to alkenes. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/197997 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 21/063 (20130101) B01J 23/42 (20130101) B01J 35/0006 (20130101) B01J 35/023 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1038 (20130101) B01J 35/1042 (20130101) B01J 35/1061 (20130101) B01J 37/12 (20130101) B01J 37/18 (20130101) B01J 37/082 (20130101) B01J 37/0207 (20130101) B01J 37/0238 (20130101) B01J 37/0244 (20130101) Acyclic or Carbocyclic Compounds C07C 5/3337 (20130101) Original (OR) Class C07C 2521/04 (20130101) C07C 2521/06 (20130101) C07C 2523/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292344 | Mao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lingling Mao (Evanston, Illinois); Weijun Ke (Evanston, Illinois); Konstantinos Stoumpos (Chicago, Illinois); Mercouri G. Kanatzidis (Wilmette, Illinois) |
| ABSTRACT | Two-dimensional halide perovskites are provided. The perovskites have two-dimensional Dion-Jacobson phases and are composed of a plurality of inorganic perovskite layers separated by 3-(aminomethyl)piperidinium (3AMP) and/or 4-(aminomethyl)piperidinium (4AMP) spacer cations. The halide perovskites may have a single perovskitizer cation or mixed perovskitizer cations. Also provided are radiation-absorbing materials comprising the perovskites and photovoltaic cells comprising the radiation-absorbing materials as photoactive materials. |
| FILED | Monday, October 14, 2019 |
| APPL NO | 17/285049 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/003 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292543 | GINLEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Samuel GINLEY (Evergreen, Colorado); Dan Austin PLATTENBERGER (Denver, Colorado) |
| ABSTRACT | Disclosed herein are new compositions of matter and methods useful for the packing of electronics in extreme environments. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/206104 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 61/16 (20130101) Original (OR) Class C08L 67/03 (20130101) C08L 79/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292572 | Percival et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen John Percival (Albuquerque, New Mexico); C. Garrett Campbell (Albuquerque, New Mexico); Mathias C. Celina (Albuquerque, New Mexico); Erik David Spoerke (Albuquerque, New Mexico); Eric John Schindelholz (Columbus, Ohio) |
| ABSTRACT | Nanocomposite anticorrosion coating can be achieved by depositing alternating, multilayers of a cross-linkable polymer and dispersed and aligned inorganic platelets followed by cross-linking of the cross-linkable polymer. The cross-linkable polymer can be an externally cross-linkable polymer that is cross-linked by diffusing a cross-linking agent into the deposited multilayer coating. Alternately, the cross-linkable polymer can be a functionalized cross-linkable polymer that is cross-linked by self-curing, thermal heat curing, or light (e.g., UV) following deposition of the multilayer coating. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/029630 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 7/148 (20130101) B05D 7/542 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/346 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/084 (20130101) Original (OR) Class C09D 7/70 (20180101) C09D 139/02 (20130101) C09D 163/00 (20130101) C09D 179/02 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 11/173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292732 | Liew et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LanzaTech, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fungmin Liew (Skokie, Illinois); Michael Koepke (Skokie, Illinois); Shilpa Nagaraju (Skokie, Illinois); Audrey Harris (Skokie, Illinois) |
| ABSTRACT | Disclosed herein are methods for production of 2-phenylethanol by microbial fermentation of substrates comprising carbon monoxide and/or carbon dioxide and further disclosed are genetically modified microorganisms for use in such methods. Additionally, the processes disclosed herein are improved methods of 2-PE production that alleviate dependence on natural and petrochemical processes. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150900 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/88 (20130101) Original (OR) Class C12N 9/90 (20130101) C12N 9/1085 (20130101) C12N 9/1092 (20130101) C12N 9/1205 (20130101) C12N 9/1294 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/22 (20130101) Enzymes C12Y 101/01025 (20130101) C12Y 102/07005 (20130101) C12Y 205/01019 (20130101) C12Y 207/01071 (20130101) C12Y 207/09001 (20130101) C12Y 401/01043 (20130101) C12Y 402/0101 (20130101) C12Y 402/01051 (20130101) C12Y 402/03004 (20130101) C12Y 402/03005 (20130101) C12Y 504/99005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292747 | Gill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan T. Gill (Boulder, Colorado); Rongming Liu (Boulder, Colorado) |
| ABSTRACT | Embodiments of the present disclosure relate to methods for creating and using engineered chimeric nucleic acid guided nuclease libraries for improved and commercially viable nuclease constructs for targeted and improved gene editing. In certain embodiments, libraries of chimeric nucleases having modules derived from two, three or more Cas12a-type species can be constructed to form chimeras representing two or more different species. In some embodiments, engineered libraries disclosed herein can be used for rapid production, identification and use for improved targeted genomic editing in a subject. In other embodiments, PAM sequence recognition by a native Cas12a-type nuclease can be selected against in libraries disclosed herein creating novel Cas12a-like chimeric nuclease libraries having increased targeting capabilities across species for improved genomic editing efficiency, reducing off-targeting and/or creating expanded target specificity. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207421 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292780 | Loque et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dominique Loque (Geneva, Switzerland); Aymerick Eudes (Emeryville, California) |
| ABSTRACT | The present invention provides an expression cassette comprising a polynucleotide that encodes a protein that diverts a monolignol precursor from a lignin biosynthesis pathway in the plant, which is operably linked to a heterologous promoter. Also provided are methods of engineering a plant having reduced lignin content, as well as plant cells, plant parts, and plant tissues from such engineered plants. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/157942 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/8255 (20130101) Original (OR) Class Enzymes C12Y 402/01118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292797 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Taek Soon Lee (Berkeley, California); Xi Wang (Emeryville, California) |
| ABSTRACT | The present invention provides for a fusion protein comprising: (a) a terpene synthase (TS), or a homolog thereof, (b) a peptide linker, and (c) a P450 enzyme, or a homolog thereof. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207097 |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class Enzymes C12Y 114/14 (20130101) C12Y 114/13106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210292870 | Case et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary E. Case (Idaho Falls, Idaho); Robert V. Fox (Idaho Falls, Idaho); Donna L. Baek (Idaho Falls, Idaho) |
| ABSTRACT | A method of removing of recovering an elemental rare earth metal comprises placing a rare earth-containing material comprising a rare earth metal in a reaction solution comprising a reducing agent and a non-aqueous solvent comprising an ionic liquid or a eutectic mixture, reducing the rare earth metal with the reducing agent to form a metallic rare earth metal and cations of the reducing agent, transferring the cations of the reducing agent from the reaction solution to an electrochemical cell through an ion exchange membrane, and reducing the cations of the reducing agent in the electrochemical cell. Related methods of forming an elemental rare earth metal, and related systems are disclosed. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/249283 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/10 (20200101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 59/00 (20130101) Original (OR) Class Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293689 | HUNYADI MURPH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SIMONA E. HUNYADI MURPH (NORTH AUGUSTA, South Carolina); HENRY T. SESSIONS (AIKEN, South Carolina); MICHAEL A. BROWN (AIKEN, South Carolina) |
| ABSTRACT | Automated apparatuses for use in examining gas sorption materials are described. Devices utilize a noncontact magnetic induction heating approach for controlling the temperature of tested materials. The apparatuses can be used to generate single or multiple isotherms simultaneously. The apparatuses can examine nanogram or microgram-scale quantities of materials of interest and can do so automatically and unattended. Pressure-composition isotherms can be provided through use of disclosed apparatuses in a period of a few hours. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826789 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0806 (20130101) Original (OR) Class G01N 2015/0866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293697 | Potyrailo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Joleyn Eileen Brewer (Clifton Park, New York) |
| ABSTRACT | A sensor system includes a sensing element having a section of a layer assembly deposited onto a substrate. The layer assembly includes plural layers of different materials. The section of the layer assembly is configured to be etched to form plural individual pillars of the plural layers of the different materials. The individual pillars are configured to be in contact with a fluid to sense one or more analyte fluid components within the fluid. The sensing element is configured to generate a sensor signal responsive to the individual pillars being in contact with the fluid. The sensor system includes one or more processors configured to receive the sensor signal from the sensing element. The one or more processors may identify the one or more analyte fluid components within the fluid and an amount of each of the analyte fluid components within the fluid based on the sensor signal. |
| FILED | Sunday, March 22, 2020 |
| APPL NO | 16/826248 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/255 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293698 | Pallares et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Roger M. Pallares (Berkeley, California); Rebecca J. Abergel (Kensington, California) |
| ABSTRACT | A colorimetric assay of lanthanide or actinide (f-block elements) samples and a sensing construct of functionalized gold nanoparticles are provided. The construct is a gold nanoparticle with hydroxypyridinone ligands on the surface. The colorimetric assay can be performed in two different ways: (1) Gold nanoparticles functionalized with hydroxypyridinone ligands are synthesized, and then added to the sample solution. The presence of f-block elements triggers the gold nanoparticle aggregation, which changes the solution color. (2) Exploiting the competition between Au3+ and cations with higher binding affinities, where the f-block elements quench the nanoparticle growth and affect the color of solution. In both methods, the change in color is used as a sensing principle to quantify the f-block element concentrations in aqueous solutions. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154317 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293924 | Chritton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (KANSAS CITY, Missouri) |
| INVENTOR(S) | Audrey L. Chritton (Kansas City, Missouri) |
| ABSTRACT | A simulation system for use in testing a radar system comprises a coarse delay module, a fine delay module, and a doppler shift module. The coarse delay module is configured to receive a first stream of digital data samples that are sampled from a radar signal at a sample time period or a second stream of digital data samples that are processed by another simulation system component and delay the digital data samples by a selectable first delay time that is greater than or equal to the sample time period. The fine delay module is configured to receive the digital data samples and filter the digital data samples to represent delay by a selectable second delay time that is less than the sample time period. The doppler shift module is configured to receive the digital data samples and adjust a value of a frequency content of the fine delayed samples. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 16/822197 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4021 (20130101) G01S 7/4052 (20130101) Original (OR) Class G01S 2007/4095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293979 | Waugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin Waugh (Boulder, Colorado); Daniel S. Dessau (Boulder, Colorado); Stephen P. Parham (Broomfield, Colorado); Thomas Nummy (Boulder, Colorado); Justin Griffith (Littleton, Colorado); Xiaoqing Zhou (Longmont, Colorado); Haoxiang Li (Boulder, Colorado) |
| ABSTRACT | A quantitative pulse count (event detection) algorithm with linearity to high count rates is accomplished by combining a high-speed, high frame rate camera with simple logic code run on a massively parallel processor such as a GPU or a FPGA. The parallel processor elements examine frames from the camera pixel by pixel to find and tag events or count pulses. The tagged events are combined to form a combined quantitative event image. |
| FILED | Sunday, June 06, 2021 |
| APPL NO | 17/340049 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/20184 (20200501) Original (OR) Class Pictorial Communication, e.g Television H04N 5/374 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294277 | Samaan et al. |
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| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nader A. Samaan (Richland, Washington); Bharat GNVSR Vyakaranam (Redmond, Washington); Jeffery E. Dagle (Richland, Washington); Yousu Chen (Mount Pleasant, South Carolina); Marcelo A. Elizondo (Seattle, Washington); Mallikarjuna R. Vallem (Richland, Washington); Pavel V. Etingov (Mukilteo, Washington); Qiuhua Huang (Richland, Washington); Xinya Li (Ithaca, New York); Blaine J. McGary (Pasco, Washington); Kirsten L. Pierce (Richland, Washington); George Chin, JR. (Richland, Washington); Dimitri V. Zarzhitsky (Everett, Washington) |
| ABSTRACT | The present disclosure describes systems and techniques that enhance effectiveness and efficiency of a contingency analysis tool that is used for studying the magnitude and likelihood of extreme contingencies and potential cascading events across a power system. The described systems and techniques include deploying the contingency analysis tool in a high-performance computing (HPC) environment and incorporating visual situational awareness approaches to allow power system engineers to quickly and efficiently evaluate multiple power system simulation models. Furthermore, the described systems and techniques include the power system contingency-analysis tool calculating and coordinating protection element settings, as well as assessing controls of the power system using small-signal nomograms, allowing power system engineers to more effectively comprehend, evaluate, and analyze causes and effects of cascading events against a topology of a power system. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/827695 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/02 (20130101) Original (OR) Class G05B 15/02 (20130101) G05B 23/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294304 | Chamie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Mahmoud El Chamie (Manchester, Connecticut); Vladimir Blasko (Avon, Connecticut) |
| ABSTRACT | A method of controlling a matrix converter system is provided. The method includes receiving an operating condition and consulting a trained Q-data structure for reward values associated with respective switching states of the switching matrix for an operating state that corresponds to the operating condition. The Q-data structure is trained using Q-learning to map a reward value predicted for respective switching states to respective discrete operating states. The method further includes sorting the reward values predicted for the respective switching states mapped to the operating state that corresponds to the operating condition, selecting a subset of the set of the mappings as a function of a result of sorting the reward values associated with the switching states of the operating state, evaluating each switching state included in the subset, and selecting an optimal switching state for the operating condition based on a result of evaluating the switching states of the subset. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826635 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4155 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 20/00 (20190101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210294646 | HASSAAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Muhammad Amber HASSAAN (Austin, Texas); Anirudh Mohan KAUSHIK (Austin, Texas); Sooraj PUTHOOR (Austin, Texas); Gokul Subramanian RAVI (Austin, Texas); Bradford BECKMANN (Bellevue, Washington); Ashwin AJI (Santa Clara, California) |
| ABSTRACT | A processor includes a task scheduling unit and a compute unit coupled to the task scheduling unit. The task scheduling unit performs a task dependency assessment of a task dependency graph and task data requirements that correspond to each task of the plurality of tasks. Based on the task dependency assessment, the task scheduling unit schedules a first task of the plurality of tasks and a second proxy object of a plurality of proxy objects specified by the task data requirements such that a memory transfer of the second proxy object of the plurality of proxy objects occurs while the first task is being executed. |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 16/824601 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 16/9024 (20190101) G06F 2209/486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296558 | ENGLUND et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dirk Robert ENGLUND (Brookline, Massachusetts); Matthew Edwin TRUSHEIM (Cambridge, Massachusetts); Matt Eichenfield (Albuquerque, New Mexico); Tomas Neuman (Cambridge, Massachusetts); Prineha Narang (Somerville, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dirk Robert ENGLUND (Brookline, Massachusetts); Matthew Edwin TRUSHEIM (Cambridge, Massachusetts); Matt Eichenfield (Albuquerque, New Mexico); Tomas Neuman (Cambridge, Massachusetts); Prineha Narang (Somerville, Massachusetts) |
| ABSTRACT | A hybrid quantum system performs high-fidelity quantum state transduction between a superconducting (SC) microwave qubit and the ground state spin system of a solid-state artificial atom. This transduction is mediated via an acoustic bus connected by piezoelectric transducers to the SC microwave qubit. For SC circuit qubits and diamond silicon vacancy centers in an optimized phononic cavity, the system can achieve quantum state transduction with fidelity exceeding 99% at a MHz-scale bandwidth. By combining the complementary strengths of SC circuit quantum computing and artificial atoms, the hybrid quantum system provides high-fidelity qubit gates with long-lived quantum memory, high-fidelity measurement, large qubit number, reconfigurable qubit connectivity, and high-fidelity state and gate teleportation through optical quantum networks. |
| FILED | Tuesday, January 19, 2021 |
| APPL NO | 17/151763 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296602 | Rand et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barry P. Rand (Princeton, New Jersey); Lianfeng Zhao (Jersey City, New Jersey) |
| ABSTRACT | Provided is a thin film semiconductor device that exploits excitonic characteristics of various organic semiconductor materials. The device may include an anode (120), a cathode (170), and a donor-acceptor heterojunction (150) disposed between the anode and the cathode. The donor-acceptor heterojunction may further include an acceptor material (404) having a highest occupied molecular orbital (HOMO) and a lowest unoccupied molecular orbital (LUMO), and a donor material (402) comprising a hybrid organic-inorganic metal halide perovskite semiconductor. Other embodiments are disclosed and additional embodiments are also possible. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 17/264037 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/001 (20130101) H01L 51/0003 (20130101) H01L 51/0026 (20130101) H01L 51/0077 (20130101) H01L 51/426 (20130101) Original (OR) Class H01L 51/4213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296607 | Spindler et al. |
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| FUNDED BY |
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| APPLICANT(S) | OLEDWorks LLC (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Spindler (Ontario, New York); Marina Kondakova (Kendall, New York) |
| ABSTRACT | An OLED lighting device comprising: a blue light-emitting unit with a blue-light fluorescent, phosphorescent or TADF emitter; a yellow light-emitting electroluminescent unit comprising a green phosphorescent emitter, a red phosphorescent emitter and at least one non-emitting host; wherein the blue light-emitting unit and the yellow light-emitting unit are separated by a mixed interlayer with two non-emitting charge-carrier materials. Desirably, the yellow-light emitting unit essentially consists of a green phosphorescent emitter, a red phosphorescent emitter and a single non-emitting host. The mixed interlayer desirably has more than 50% of a hole-transporting material and an electron-transporting material. The Triplet Energy of both materials in the mixed interlayer can be higher than the Triplet Energies of the R and G phosphorescent dopants. The HOMOs of both materials in the mixed interlayer are more negative than the HOMO of the host in the yellow unit but less negative than the HOMO of the host in the blue unit. The LUMOs of the materials in the mixed interlayer can be more negative than the LUMO of the host in the yellow unit but less negative than the LUMO of the host in the blue unit. The OLED lighting device is spectrally tunable according to the supplied power. |
| FILED | Wednesday, February 10, 2021 |
| APPL NO | 17/172398 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5016 (20130101) H01L 51/5044 (20130101) Original (OR) Class H01L 51/5206 (20130101) H01L 51/5221 (20130101) H01L 2251/533 (20130101) H01L 2251/552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296676 | Gervasio |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dominic Francis Gervasio (Tucson, Arizona) |
| ABSTRACT | A novel electrochemical hydrogen compressor material technology system comprising a composite polymer membrane made from a blend of inorganic and organic polymers, the preparation and the use thereof. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221729 |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 43/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/8605 (20130101) H01M 8/0258 (20130101) H01M 8/0267 (20130101) H01M 8/1213 (20130101) Original (OR) Class H01M 8/04029 (20130101) H01M 8/04074 (20130101) H01M 2008/1095 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296733 | Carlson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Optodot Corporation (Devens, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A. Carlson (Cambridge, Massachusetts); Benjamin Sloan (Exeter, New Hampshire); David W. Avison (Boxborough, Massachusetts) |
| ABSTRACT | Provided is a lithium battery, wherein the battery comprises an anode, a cathode, wherein the cathode comprises one or more transition metals, an electrolyte, and a porous separator interposed between the cathode and anode, wherein the separator comprises an anionic compound. Also provided are methods of manufacturing such batteries. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338214 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/20 (20130101) H01G 11/50 (20130101) H01G 11/52 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0585 (20130101) H01M 50/46 (20210101) H01M 50/446 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20210290787 | MAGDA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LUMIPHORE, INC. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darren MAGDA (San Leandro, California); David TATUM (Berkeley, California); Nathaniel G. BUTLIN (Pacifica, California) |
| ABSTRACT | The invention relates to chemical compounds and complexes that can be used in therapeutic and diagnostic applications. In various embodiments, the invention described herein pertains to the diagnosis, imaging, and/or treatment of pathogenic cell populations. In particular, the invention described herein pertains to the diagnosis, imaging, and/or treatment of diseases caused by PSMA express-ing cells, such as prostate cancer cells, using compounds capable of targeting PSMA expressing cells. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 17/253550 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 49/0056 (20130101) A61K 51/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293782 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George Guikai Wu (Laguna Hills, California); Yonglei Shang (Laguna Hills, California) |
| ABSTRACT | Methods and systems for performing assays in compartmentalized nano-volumes to screen for functional bispecific or multispecific biologics, including: providing a plurality of at least two distinct types of cells, wherein two or more first-type cells are engineered to express substantially a single genetic-variant per cell for a bispecific or multispecific biologic in a secreted form, wherein two or more second-type cells are selected or engineered to produce a positive reporter molecule signal that is triggered by a functional variant of the said biologic expressed by a first-type cell; providing a plurality of compartmentalized nano-volumes, wherein two or more nano-volumes are each provided with substantially one first-type cell, and one or more second-type cell(s); incubating the said nano-volumes over a period of time to allow the expression and secretion of the said biologics inside the said nano-volumes; collecting data representing the positive reporter molecule signal triggered by secreted biologics inside the said nano-volumes, and recovering cells from the nano-volumes with the positive reporter molecule signal and extracting the genetic information representing respective functional variants of the biologics. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221688 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295673 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Microsensor Labs, LLC (Chicago, Illinois) |
| INVENTOR(S) | Peng Liu (Chicago, Illinois); Yang Liu (Chicago, Illinois) |
| ABSTRACT | A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341789 |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/245 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210296946 | KRISHNASAMY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jayaraman KRISHNASAMY (Boxborough, Massachusetts); Martin Hosek (Salem, New Hampshire); Dennis Poole (East Derry, New Hampshire) |
| ABSTRACT | An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/330707 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/126 (20130101) Gearing F16H 25/20 (20130101) F16H 2025/2081 (20130101) Dynamo-electric Machines H02K 1/146 (20130101) Original (OR) Class H02K 1/278 (20130101) H02K 7/06 (20130101) H02K 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20210290148 | Najafi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Arizona Board of Regents on behalf of Arizona State University, a body corporate duly formed in a... (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bijan Najafi (Houston, Texas); Javad Razjouyan (Houston, Texas); He Zhou (Houston, Texas); Mark Kunik (Bellaire, Texas) |
| ABSTRACT | An instrumented trail-making task (iTMT) platform includes a wearable sensor and interactive interface technology configured to identify cognitive-cognitive impairment in individuals such as older adults. The iTMT platform may be programmed with neuropsychological tests for assessing individuals. The iTMT may provide information on visual search, scanning, speed of processing, mental flexibility, and/or executive functions as well as physical biomarkers of motor performance including slowness, weakness, exclusion, and/or motor planning error. Results of tests administered by the iTMT system may be reported to a patient or caregiver and used in identifying cognitive-motor impairment among individuals suffering from cognitive impairment, dementia, and/or those with frailty status, and/or cognitive frailty, and/or high risk of falling, and/or high likelihood of decline in cognitive-motor over time. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 16/334571 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1124 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 2562/0219 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210290823 | Lancaster et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jordan J. Lancaster (Tucson, Arizona); Steven Goldman (Tucson, Arizona) |
| ABSTRACT | Disclosed herein are contractile cell constructs, methods for using them to treat disease, and methods for making them. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/335687 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/18 (20130101) A61K 38/2292 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/367 (20130101) A61L 27/3826 (20130101) Original (OR) Class A61L 27/3873 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) C12N 2506/1315 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293825 | Bergan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond Bergan (Portland, Oregon); Ryan Gordon (Portland, Oregon) |
| ABSTRACT | Disclosed are methods for identifying an agent of interest that alters binding or activity of a client protein to a chaperone and kits thereof. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 17/262556 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2440/14 (20130101) G01N 2500/02 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20210295144 | Restelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alessandro Restelli (Greenbelt, Maryland); Daniel P. Lathrop (University Park, Maryland); Heidi Komkov (Albuquerque, New Mexico) |
| ABSTRACT | A variable sensitivity node for a neural network that can be implemented as an information processing device such as an ASIC, and can be adjusted simply by applying immediate weights or parameters that change and/or amplify or de-amplify the output of the nodes. The information processing device has one or more nodes each with an input setting channel, a logic element configured to translate the input signal into the output signal based on a mathematical function that includes a parameter setting, and a parameter-setting element configured to set the parameter setting based on a control input to the input setting channel, thereby altering the mathematical relationship of the logic element without compromising speed and efficiency. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208399 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0635 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210295861 | BALASUBRAMANIYAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vijay BALASUBRAMANIYAN (Atlanta, Georgia); Mustaque AHAMAD (Atlanta, Georgia); Patrick Gerard TRAYNOR (Decatur, Georgia); Michael Thomas HUNTER (Atlanta, Georgia); Aamir POONAWALLA (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338523 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/162 (20130101) G06F 16/22 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 25/51 (20130101) Original (OR) Class Telephonic Communication H04M 3/2281 (20130101) H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20210292169 | Barak |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Phillip Warren Barak (Madison, Wisconsin) |
| ABSTRACT | A method of producing ammonium phosphates from at least one mineral containing phosphate and an element which is calcium, magnesium, iron, or aluminum. The method includes contacting the at least one mineral (or a combination of them) with a cation exchanger for a time and at a temperature sufficient to yield phosphoric acid from the mineral. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338825 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/16 (20130101) Non-metallic Elements; Compounds Thereof; C01B 25/28 (20130101) Original (OR) Class C01B 25/321 (20130101) Phosphatic Fertilisers C05B 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20210291136 | Jacobson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gen9, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Gen9, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Joseph Jacobson (Newton, Massachusetts); Larry Li-Yang Chu (Cambridge, Massachusetts) |
| ABSTRACT | Methods and apparatus relate to the synthesis of high fidelity polynucleotides and to the reduction of sequence errors generated during synthesis of nucleic acids on a solid support. Specifically, design of support-bound template oligonucleotides is disclosed. Assembly methods include cycles of annealing, stringent wash and extension of polynucleotides comprising a sequence region complementary to immobilized template oligonucleotides. The error free synthetic nucleic acids generated therefrom can be used for a variety of applications, including synthesis of biofuels and value-added pharmaceutical products. |
| FILED | Monday, June 07, 2021 |
| APPL NO | 17/341286 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00608 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1031 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6837 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20210290806 | McCreery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| ASSIGNEE(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| INVENTOR(S) | Thomas McCreery (Sykesville, Maryland); Wayne A. Bryden (Sykesville, Maryland); Emily Caton (Sykesville, Maryland) |
| ABSTRACT | Mobile decontamination systems and microwave assisted decontamination methods for decontaminating a variety of contaminated surfaces disposed external to the system are disclosed. The systems and methods comprise treating the surfaces with benign chemical formulations followed by exposing to microwave irradiation for short periods of time to achieve at least 6-log reduction in biological contaminants including viruses and spores of B. anthracis, B. thuringiensis, and P. roqueforti. The formulations comprise a percarbonate and surfactant in water. |
| FILED | Sunday, May 30, 2021 |
| APPL NO | 17/334778 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/12 (20130101) A61L 2/22 (20130101) Original (OR) Class A61L 2/24 (20130101) A61L 2/26 (20130101) A61L 2202/14 (20130101) A61L 2202/15 (20130101) A61L 2202/16 (20130101) A61L 2202/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20210296106 | Manicke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Nicholas Manicke (Zionsville, Indiana); Chengsen Zhang (Indianapolis, Indiana) |
| ABSTRACT | Mass spectrometry cartridge including a base in mechanical communication with a spray substrate holder, an absorbent pad between the base and the spray substrate holder, a translatable sample well holder interposed between the spray substrate holder and a top cover, the top cover configured to house a conductive element, wherein when the translatable sample well holder is in a first position, the translatable well holder is vertically above the absorbent pad, when the translatable sample well holder is in a second position, the translatable well holder is vertically above a spray substrate are disclosed. Methods of analyzing a sample are also disclosed. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 16/334329 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/16 (20130101) H01J 49/0409 (20130101) Original (OR) Class H01J 49/0431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 20210292396 | SOK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devin SOK (San Diego, California); Joseph JARDINE (La Jolla, California) |
| ABSTRACT | The present disclosure relates to anti-HIV Env antibodies and their use in the treatment or prevention of HIV/AIDS. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 17/263490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20210289746 | Villalobos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizone State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesus Rene Villalobos (Mesa, Arizona); Octavio Sanchez (Hermosillo, Mexico); Cesar Meneses (Hermosillo, Mexico) |
| ABSTRACT | In accordance with embodiments disclosed herein, there are provided methods and systems for real-time beef cattle monitoring utilizing Radio-Frequency Identification (RFID) based technologies. For example, there is disclosed a system having at least a memory to store instructions; a processor to execute the instructions; a database to store data for heads of livestock, wherein each head of livestock is individually identified via a Radio-Frequency Identification (RFID) tag, the RFID tag uniquely identifying each of the heads of livestock to the system; a plurality of antennas to read information transmitted from the RFID tags; a transactional and analytical server to receive the information transmitted from the RFID tags and to store the information in the database; wherein the transactional and analytical server to further analyze the information stored in the database to identify when each head of livestock is present within a defined feeding zone; and monitoring the heads of livestock for anomalous feeding behavior based on the analysis. Other related embodiments are disclosed. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826709 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 5/01 (20130101) A01K 5/02 (20130101) A01K 11/004 (20130101) Original (OR) Class A01K 29/005 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10356 (20130101) G06K 19/07758 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210293591 | KERTESZ et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S (Washington, District of Columbia); URBANALTA CORP (Cincinnati, Ohio) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S (Washington, District of Columbia); URBANALTA CORP (Cincinnati, Ohio) |
| INVENTOR(S) | Ruben KERTESZ (Cincinnati, Ohio); Daniel J. MURRAY, JR. (Cincinnati, Ohio); Michael BOLAN (Cincinnati, Ohio); Ryan ANDERSON (Cincinnati, Ohio); Chunsheng FANG (Redwood City, California) |
| ABSTRACT | A flow imaging and monitoring system for synchronized management of wide area drainage that includes an interposer for supporting monitoring and management equipment in a manhole, a module for illuminating water flowing in pipes at the base of the manhole, a module for monitoring responses to reflected light, a sealed and rechargeable battery pack, and a data analysis and management system to interpret data streams in real time. The interposer can be adjusted to fit the diameter of the manhole and can be adjusted to be placed under the manhole cover. The module for illuminating the flowing water can be adjusted to generate various frequencies. The support structures for the modules can be adjusted for varying pitch, roll and yaw with respect to the manhole. The data analysis and management system is supported by cloud computing. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343221 |
| CURRENT CPC | Sewers; Cesspools E03F 7/00 (20130101) E03F 2201/20 (20130101) E03F 2201/40 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/02 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/002 (20130101) G01F 1/66 (20130101) G01F 1/661 (20130101) G01F 1/662 (20130101) Original (OR) Class G01F 1/666 (20130101) G01F 1/704 (20130101) G01F 1/7086 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4257 (20130101) H01M 50/20 (20210101) Technical Subjects Covered by Former US Classification Y10T 137/8158 (20150401) Y10T 137/8359 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, September 23, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page