FedInvent™ Patent Applications
Application Details for Thursday, November 18, 2021
This page was updated on Thursday, November 18, 2021 at 11:41 PM GMT
Department of Health and Human Services (HHS)
| US 20210353142 | Zhang et al. |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei Zhang (Ann Arbor, Michigan); Xueding Wang (Ann Arbor, Michigan); Yannis Paulus (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to systems for low-energy (e.g., 1.0 nJ-7.0 nJ) photoacoustic microscopy and methods for employing such systems. In certain embodiments, such systems employ a low-energy nanosecond pulsed laser beam (NPLB), at least two amplifiers, and a data acquisition system with at least three channels to generate at least three digital signals (e.g., which are averaged and normalized to the energy of the NPLB). In other embodiments, provided herein are systems for combined use of photoacoustic microscopy, dye-based microscopy (e.g., with fluorescein), and optical coherence tomography. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/320755 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 5/0095 (20130101) Optical Elements, Systems, or Apparatus G02B 27/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353144 | Yates et al. |
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| FUNDED BY |
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| APPLICANT(S) | Retivue, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Retivue, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Paul Andrew Yates (Charlottesville, Virginia); Ming Lai (Charlottesville, Virginia); Ta-Wei Yi (New Taipei City, Taiwan); Alex Martinez (Charlottesville, Virginia) |
| ABSTRACT | A wide field fundus camera is disclosed to implement multiple illumination beam projectors and to capture multiple retinal images at various viewing angles to facilitate wide field retinal examination. The wide field fundus camera contemplates an ultra-wide field lens that can provide edge to edge imaging of the entire retina at a single alignment. The wide field fundus camera contemplates configuration of said multiple illumination beam projectors to provide visualization of retina and Purkinje reflections simultaneously to facilitate determination of proper camera alignment with the eye. The wide field fundus camera further contemplates control of multiple illumination beam projectors in a programmable manner to further assess alignment of each illumination beam projector with the eye and to capture said multiple retinal images. The wide field fundus camera further contemplates a consumer image recording device with fast auto focusing and fast continuous image capture to make the device easy to use and quick to respond. The wide field fundus camera further contemplates narrow and broad slit beam illuminations to enhance autofocusing, imaging through less transparent crystalline lens, and reduction of haze due to reflected and scattered light from camera and ocular surfaces other than the retina. The wide field camera contemplates a real-time algorithm to reduce said reflected and scattered light haze in said retinal images. The wide field camera further contemplates automated montage of said multiple retinal images into a single wide field FOV retinal montage and automated removal reflected and scattered light haze from said retinal montage. The wide field camera further contemplates to automatically identify camera alignment with the eye and standardize an alignment procedure to simplify reflected and scattered light haze to facilitate dehaze and auto montage of said retinal images. |
| FILED | Tuesday, January 26, 2021 |
| APPL NO | 17/158632 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/00 (20130101) A61B 3/0008 (20130101) A61B 3/12 (20130101) A61B 3/14 (20130101) A61B 3/152 (20130101) A61B 3/158 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/50 (20130101) G06T 2207/20172 (20130101) Pictorial Communication, e.g Television H04N 7/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353147 | Melodia et al. |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
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| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts); Laura Galluccio (Trecastagni, Italy); Sergio Palazzo (San Giovanni la Punta, Italy) |
| ABSTRACT | Methods and devices for transmitting and receiving data through biological tissue using ultrasonic pulses are described. Methods of the present invention may set an initial time-hopping frame length and an initial spreading code length for data transmission. A request-to-transmit may be sent from a transmitter over a control channel at the initial frame and code length. The receiver may respond to the transmitter with a clear-to-transmit packet having feedback information. The feedback information can be used to improve a forward time-hopping frame length and a forward spreading code length. Embodiments of the invention may involve a body area network or body surface network comprising a plurality of implanted sensor nodes operating according to the disclosed invention. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/157251 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0015 (20130101) A61B 5/0024 (20130101) A61B 5/026 (20130101) A61B 5/0028 (20130101) Original (OR) Class A61B 5/0031 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 23/02 (20130101) Transmission H04B 1/71635 (20130101) Selecting H04Q 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353150 | Wood et al. |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
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| INVENTOR(S) | Bradford J. Wood (Bethesda, Maryland); Baris Turkbey (Bethesda, Maryland); Sheng Xu (Bethesda, Maryland); Evrim Turkbey (Bethesda, Maryland); Peng An (Bethesda, Maryland); Gianpaolo Carrafiello (Bethesda, Maryland); Robert Suh (Bethesda, Maryland); Hayet Amalou (Bethesda, Maryland); Amel Amalou (Bethesda, Maryland); Robin Therme (Bethesda, Maryland); Brad Dunlap (Bethesda, Maryland); Matt Berger (Bethesda, Maryland); Yash Agrawal (Bethesda, Maryland); Geoff Wagner (Bethesda, Maryland); Kurt Haupt (Bethesda, Maryland); Shane Anderson (Bethesda, Maryland); Anna Maria Lerardi (Bethesda, Maryland) |
| ABSTRACT | Systems, devices, and methods for isolating and protecting patients during medical imaging procedures. The devices generally related to disposable personal protective equipment (PPE) that may be used to isolate patients and prevent cross-contamination of infectious diseases during medical imaging. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/323763 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0046 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/70 (20130101) A61B 5/6831 (20130101) A61B 5/7203 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0666 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353192 | Bagwell et al. |
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| APPLICANT(S) | Actuated Medical, Inc. (Bellefonte, Pennsylvania) |
| ASSIGNEE(S) | Actuated Medical, Inc. (Bellefonte, Pennsylvania) |
| INVENTOR(S) | Roger B Bagwell (Bellefonte, Pennsylvania); Casey A. Scruggs (Bellefonte, Pennsylvania); Eric M. Steffan (Karthaus, Pennsylvania); Robert Van Ess (State College, Pennsylvania) |
| ABSTRACT | A lancing device with an ejector that is movably retained with a housing in proximity to a lancet and is selectively movable between a home position, a first eject position, an intermediate position defined by contact of the ejector with the lancet, and a second eject position. The ejector is rotatable to move from the home to first eject position and is linearly translatable to move between the first and second eject positions. The ejector includes an arm that extends within the housing and engages the lancet, an exterior portion that is actuated by a user, and a post extending therebetween. The post extends through a slot in the housing which limits the linear movement and direction of the ejector. Upon rotation of the ejector, the arm extends through an opening at the rear of the carriage holding the lancet to permit access to the lancet. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/381838 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1519 (20130101) A61B 5/14532 (20130101) A61B 5/150137 (20130101) Original (OR) Class A61B 5/150259 (20130101) A61B 2503/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353224 | Etkin et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Board of Regents, The University of Texas System (Austin, Texas) |
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| INVENTOR(S) | Amit Etkin (Palo Alto, California); Madhukar Trivedi (Dallas, Texas); Wei Wu (Palo Alto, California) |
| ABSTRACT | Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 17/282624 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/165 (20130101) A61B 5/168 (20130101) A61B 5/245 (20210101) A61B 5/374 (20210101) A61B 5/377 (20210101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/4848 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 2562/0223 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36053 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/4808 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 40/67 (20180101) G16H 50/20 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353439 | Norman et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); INSERM (Institut National de la Santé et de la Recherche Médicale) (Paris, France); CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (Paris, France) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); INSERM (Institut National de la Santé et de la Recherche Médicale) (Paris, France); CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (Paris, France) |
| INVENTOR(S) | Sumner L Norman (Pasadena, California); David Maresca (Pasadena, California); Vasileios Christopoulos (Riverside, California); Mikhail Shapiro (Pasadena, California); Richard A. Andersen (Pasadena, California); Mickael Tanter (Paris, France); Charlie Demene (Paris, France) |
| ABSTRACT | Methods and systems are provided for decoding movement intentions using functional ultrasound (fUS) imaging of the brain. In one example, decoding movement intentions include determining a memory phase of a cognitive state of the brain, the memory phase between a gaze fixation phase and movement execution phase, and determining one or more movement intentions including one or more of intended effector (e.g., hand, eye) and intended direction (e.g., right, left) according to a machine learning algorithm trained to classify one or more movement intentions simultaneously. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318821 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/70 (20130101) Original (OR) Class A61F 4/00 (20130101) A61F 2002/704 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353566 | Tsai et al. |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Massachusetts, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Li-Huei Tsai (Cambridge, Massachusetts); Yuan-Ta Lin (Medford, Massachusetts); Julia Bonner (Somerville, Massachusetts); Priyanka Narayan (Cambridge, Massachusetts); Grzegorz Sienski (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods of using choline supplementation for treating APOE4-related disorders. In particular the methods are accomplished by administering choline treatment paradigms to re-establish lipid homeostasis in APOE4 carriers. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318921 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353568 | Girardi et al. |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Michael Girardi (Madison, Connecticut); Julia Lewis (Clinton, Connecticut) |
| ABSTRACT | Described herein are methods and compositions useful to reduce (partially/inhibit or completely—prevent) skin cancer development in an individual in need thereof. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 17/276800 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/165 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353581 | Mohsen |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
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| INVENTOR(S) | Al-Walid A. Mohsen (Gibsonia, Pennsylvania) |
| ABSTRACT | A method of treating medium chain acyl-CoA dehydrogenase deficiency, very long chain acyl-CoA dehydrogenase deficiency, long chain hydroxyacyl-CoA dehydrogenase deficiency, trifunctional protein deficiency, or CPT II deficiency in a patient is provided comprising administering to the patient a therapeutic amount of a triglyceride or other conjugated fatty acid that bypasses or leads to an intermediate that bypasses the deficient enzyme. Amino acid-conjugated fatty acids also are provided as well as compositions comprising the amino acid-conjugated fatty acids. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387299 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/221 (20130101) Original (OR) Class A61K 31/232 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353585 | LAMMERDING et al. |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
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| INVENTOR(S) | Jan LAMMERDING (Ithaca, New York); Tyler J. KIRBY (Brooktondale, New York); Gregory R. FEDORCHAK (Ithaca, New York); Ashley J. EARLE (Dryden, New York) |
| ABSTRACT | The present application relates to methods of treating a laminopathy affecting skeletal or cardiac muscle in a subject. The methods involve selecting a subject who has a laminopathy affecting skeletal or cardiac muscle. In some embodiments, the methods involve administering, to the selected subject, an inhibitor of a protein associated with a DNA damage response (DDR) pathway to treat the laminopathy affecting skeletal or cardiac muscle in the subject. In other embodiments, the methods involve administering, to the selected subject, a microtubule stabilizing agent and a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor to treat the laminopathy affecting skeletal or cardiac muscle in the subject. Also disclosed are pharmaceutical compositions comprising an inhibitor of a protein associated with a DNA damage response (DDR) pathway, a microtubule stabilizing agent, and/or a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 17/274131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353610 | WANG et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); AGIOS PHARMACEUTICALS, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaomeng WANG (Ann Arbor, Michigan); Shilin XU (Ann Arbor, Michigan); Angelo AGUILAR (Ann Arbor, Michigan); Liyue HUANG (Ann Arbor, Michigan); Tianfeng XU (Ann Arbor, Michigan); Meng ZHANG (Ann Arbor, Michigan); Renqi XU (Ann Arbor, Michigan); Fuming XU (Ann Arbor, Michigan); Haibin ZHOU (Ann Arbor, Michigan); Tao LIU (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds represented by Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1b, R1c, E, G, and Q are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to inhibition of menin. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 17/277954 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/277 (20130101) A61K 31/454 (20130101) Original (OR) Class A61K 31/4523 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 271/24 (20130101) Heterocyclic Compounds C07D 401/06 (20130101) C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353618 | Tseng et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hsian-Rong Tseng (Los Angeles, California); Yazhen Zhu (Los Angeles, California) |
| ABSTRACT | Compositions for delivering a drug to a subject having: a plurality of self-assembled supramolecular nanoparticles (SMNPs), each of the plurality of self-assembled supramolecular nanoparticles (SMNPs) having: a plurality of binding components, each having a plurality of binding regions; a plurality of cores that are suitable to at least provide some mechanical structure to the plurality of self-assembled supramolecular nanoparticles (SMNPs), the plurality of cores comprising at least one core binding element adapted to bind to the binding regions to form a first inclusion complex; a plurality of terminating components, each having a single terminating binding element that binds to remaining binding regions of one of said plurality of binding components by forming a second inclusion complex; the drug; and a reporter agent, and methods of use thereof. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/290605 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/51 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 47/54 (20170801) A61K 47/60 (20170801) A61K 47/547 (20170801) A61K 47/645 (20170801) A61K 47/6925 (20170801) A61K 49/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353619 | Tyner et al. |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
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| INVENTOR(S) | Jeffrey W. Tyner (Portland, Oregon); Haijiao Zhang (Portland, Oregon) |
| ABSTRACT | Provided herein are methods and therapeutic combinations useful in the treatment of venetoclax-resistant Acute Myeloid Leukemia and of venetoclax-sensitive Acute Myeloid Leukemia. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 17/290649 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/5355 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353620 | Anathy et al. |
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| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
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| INVENTOR(S) | Vikas Anathy (Essex Junction, Vermont); Nicolas Chamberlain (Burlington, Vermont); Amit Kumar (Burlington, Vermont) |
| ABSTRACT | Compositions and methods involving protein disulfide isomerase (PDI) inhibitors, such as protein disulfide isomerase A3 (PDIA3) inhibitory compounds, for human coronavirus, such as severe acute respiratory syndrome (SARS) virus (e.g., SARS-CoV-2), therapies are disclosed herein. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/320069 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) A61K 31/427 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/4965 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 35/16 (20130101) A61K 39/42 (20130101) A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353626 | SUNAHARA et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); FRIEDRICH-ALEXANDER-UNIVERSITÄT ERLANGEN-NÜRNBERG (Erlangen, Germany); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
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| INVENTOR(S) | Roger K. SUNAHARA (San Diego, California); Mary J. CLARK (San Diego, California); Brian K. KOBILKA (Stanford, California); Cheng ZHANG (Pittsburgh, Pennsylvania); Xiangyu LIU (Beijing, China PRC); Peter GMEINER (Erlangen, Germany); Anne STÖSSEL (Erlangen, Germany); Harald HÜBNER (Erlangen, Germany); Daniela DENGLER (Erlangen, Germany); Markus STANEK (Erlangen, Germany); Brian S. SHOICHET (San Francisco, California); Magdalena KORCZYNSKA (San Francisco, California); Jacob P. MAHONEY (Stanford, California); Jonas KAINDL (Erlangen, Germany) |
| ABSTRACT | Provided herein are modulators of beta-adrenergic receptors. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 17/048998 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/84 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353639 | KANG et al. |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sumin KANG (Atlanta, Georgia); Jing CHEN (Atlanta, Georgia); Lingtao JIN (Atlanta, Georgia) |
| ABSTRACT | Described are methods of treating cancer comprising administering an effective amount of a platinum-based chemotherapy agent in combination with a microtubule associated serine/threonine-protein kinase (MAST) inhibitor, e.g., MAST1, and/or other kinase inhibitor to a subject in need thereof. Also described are methods of detecting amounts of MAST1 in a sample thereby determining whether the subject is sensitive or resistant to a platinum-based chemotherapy agent or combination of chemotherapy agents comprising the same. Kits comprising a platinum-based chemotherapy agent and a microtubule associated serine/threonine-protein kinase (MAST) inhibitor are also described. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/963454 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/553 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353675 | Schneider et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dina Schneider (Potomac, Maryland); Rimas J. Orentas (Seattle, Washington); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing CD38 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/331733 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 16/2896 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353710 | Duh et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elia Duh (Baltimore, Maryland); Zhenhua Xu (Baltimore, Maryland); Lingli Zhou (Baltimore, Maryland); Seulki Lee (Baltimore, Maryland); Yumin Oh (Baltimore, Maryland) |
| ABSTRACT | In one aspect, GLP-1r agonists including long-acting PEGylated exenatide (NLY01), exenatide, liraglutide, exenatide LAR (long acting), taspoglutide, albiglutide, dulaglutide, lixisenatide, semaglutide, LY2189265 are used to treat ocular ischemic, inflammatory, angiogenic, and/or degenerative conditions. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/194177 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353712 | Hageman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Hageman (Salt Lake City, Utah); Yingbin Fu (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein are methods and compositions for the diagnosis and treatment of Vascular Associated Maculopathy, or a symptom thereof, in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of one or more symptoms associated with Vascular Associated Maculopathy Disclosed in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of severe maculopathy or late stage maculopathy in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of resolving aberrant choriocapillaris lobules in a subject. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 16/806887 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 31/225 (20130101) A61K 31/4422 (20130101) A61K 38/005 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 38/1709 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353715 | JOHN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MandalMed, Inc. (San Francisco, California) |
| ASSIGNEE(S) | MandalMed, Inc. (San Francisco, California) |
| INVENTOR(S) | Constance M. JOHN (San Francisco, California); Khalil MOUNZIH (San Francisco, California) |
| ABSTRACT | Methods of reducing, treating, or reversing liver fibrosis in a subject in need thereof comprising administering Galectin-3C, are provided. Also provided are Galectin-3C fusion proteins with increased stability. |
| FILED | Thursday, September 19, 2019 |
| APPL NO | 17/277719 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1732 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353716 | Little et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Steven R. Little (Allison Park, Pennsylvania); Andrew Jason Glowacki (Pittsburgh, Pennsylvania) |
| ABSTRACT | Controlled release of VIP from PLGA microparticles was accomplished and varied through use of different polymer molecular sizes, addition of solutes to the inner aqueous phase, and use of our computer model. Released VIP from microparticles appeared to be bioactive and caused DCs to produce more CCL22 than DCs treated with blank particles at 7 and 24 hours. Additionally, DCs treated with VIP microparticle releasates recruited higher percentages of FoxP3+ T-cells in in vitro chemotaxis studies. Testing in a mouse model in vivo indicated that VIP microparticles have significant therapeutic potential to treat periodontal disease by reducing the bone loss in infected mice relative to the blank group. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/362536 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 38/2278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353726 | BALU-IYER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sathy BALU-IYER (Amherst, New York); Richard BANKERT (Eden, New York); Radha RAMAKRISHNAN (Plainsboro, New Jersey); Robert DINGMAN (Henrietta, New York); Vandana IYER (Amherst, New York); Jennifer SCHNEIDER (Boston, Massachusetts); Fiona YAU GLASSMAN (Central Islip, New York); Nhan Hanh NGUYEN (Amherst, New York) |
| ABSTRACT | Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387239 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/436 (20130101) A61K 39/00 (20130101) Original (OR) Class A61K 39/001 (20130101) A61K 39/39 (20130101) A61K 47/24 (20130101) A61K 2039/58 (20130101) A61K 2039/545 (20130101) A61K 2039/577 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353731 | Vaughan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SEATTLE CHILDREN'S HOSPITAL DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | SEATTLE CHILDREN'S HOSPITAL DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Ashley M. Vaughan (Seattle, Washington); Stefan H.I. Kappe (Seattle, Washington); Dorender A. Dankwa (Seattle, Washington) |
| ABSTRACT | The disclosure relates to doubly attenuated malaria parasites that have had the functionality of LISP2 and PlasMei2 genes interrupted through genetic manipulation. The double attenuated malaria parasites disclosed herein are useful for methods and compositions for stimulating of vertebrate host immune systems because of the complete cessation of lifecycle progression in the late liver stage, while providing a comprehensive antigenic presentation representing wildtype liver stage parasites. The disclosure also relates to the additional blood stage and gametocyte antigens to compositions of genetically attenuated malaria parasites (GAPs) to enhance efficient immune stimulation and prevention of disease and transmission related to the presence of blood stage parasites. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/163932 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/522 (20130101) Peptides C07K 14/445 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353739 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Baoming Jiang (Atlanta, Georgia); Roger I. Glass (Atlanta, Georgia); Jean-Francois Saluzzo (La-Gaude, France) |
| ABSTRACT | Methods of thermally inactivating a rotavirus are provided according to the present invention which include exposing the rotavirus to a temperature in the range of about 50° C.-80° C., inclusive, for an incubation time sufficient to render the rotavirus incapable of replication or infection. The thermally inactivated rotavirus is antigenic and retains a substantially intact rotavirus particle structure. Vaccine compositions and methods of vaccinating a subject against rotavirus are provided which include generation and use of thermally inactivated rotavirus. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385416 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 2039/5252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353740 | Kwong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Li Ou (Potomac, Maryland); John Mascola (Rockville, Maryland); Baoshan Zhang (Bethesda, Maryland); Kai Xu (Rockville, Maryland); Wing-Pui Kong (Germantown, Maryland); Yaroslav Tsybovsky (Brunswick, Maryland); Cara W. Chao (Bethesda, Maryland); Jeffrey Boyington (Clarksburg, Maryland); Yiran Wang (Bethesda, Maryland) |
| ABSTRACT | Embodiments of immunogenic conjugates including the HIV-1 Env fusion peptide and methods of their use and production are disclosed. In several embodiments, the immunogenic conjugates can be used to generate an immune response to HIV-1 Env in a subject, for example, to treat or prevent an HIV-1 infection in the subject. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 17/277694 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1658 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/644 (20170801) A61K 47/646 (20170801) A61K 47/6925 (20170801) A61K 2039/645 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353748 | JIN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lei JIN (Gainesville, Florida) |
| ABSTRACT | Described herein are novel vaccine compositions and methods for use thereof in inducing an immune response in a subject especially aged subjects. Specifically exemplified are vaccine compositions that include an antigen; a cyclic dinucleotide; soluble tumor necrosis factor (TNF); or a CD64 antibody or antibody fragment. Optionally, the vaccine composition comprises a TNF conjugated with a moDC targeting moiety in addition to or in place of TNF or CD64 antibody or antibody fragment, or both TNF and CD64 antibody or antibody fragment. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/280986 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/092 (20130101) A61K 39/3955 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353751 | Kaufman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Daniel Kaufman (Los Angeles, California); Jide Tian (Los Angeles, California) |
| ABSTRACT | The present application relates to a combination therapy for treatment of inflammatory diseases comprising an immunomodulator compound and a GABA-receptor agonist in an amount effective to reduce inflammation and ameliorate disease. In certain embodiments, the present application relates to treatment of T1D by administering an immunomodulator compound and a GABA-receptor agonist in an amount effective to prevent, reduce, and/or treat hyperglycemia in the human or animal subject. In certain embodiments, the immunomodulator compound and GABA-receptor agonist are administered in an amount effective to control autoimmune responses and safely increase β-cell mass and function in the context of established β-cell autoimmunity. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 17/286030 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/42 (20130101) A61K 31/145 (20130101) A61K 31/197 (20130101) A61K 31/351 (20130101) A61K 31/401 (20130101) A61K 31/405 (20130101) A61K 31/407 (20130101) A61K 31/436 (20130101) A61K 31/437 (20130101) A61K 31/515 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/5377 (20130101) A61K 31/5415 (20130101) A61K 31/5513 (20130101) A61K 38/13 (20130101) A61K 38/215 (20130101) A61K 39/3955 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353784 | Bargonetti-Chavarria et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jill Bargonetti-Chavarria (Bronx, New York); Gu Xiao (New York, New York); Brian Zeglis (New York, New York); George Annor (New York, New York); Kimberly Fung (New York, New York) |
| ABSTRACT | Peptide formulations of a general formula of X-mtp53ODP, where mtp53ODP is a peptide that binds to tetrameric mp53 tetramers in vivo. X is a detection agent, such a fluorophore or radioligand, and/or a DNA-damaging agent. The primary structures of suitable mtp53ODPs are given as SEQ ID NOS: 1-8. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318706 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 49/0032 (20130101) A61K 49/0056 (20130101) A61K 51/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20210353833 — NERVE REPAIR SCAFFOLDS HAVING HIGH MICROCHANNEL VOLUME AND METHODS FOR MAKING THE SAME
| US 20210353833 | SAKAMOTO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. SAKAMOTO (Ann Arbor, Michigan); Dena SHAHRIARI (Woodland Hills, California); Mark H. TUSZYNSKI (La Jolla, California); Wendy CAMPANA (La Jolla, California); Yacov KOFFLER (San Diego, California) |
| ABSTRACT | Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels. |
| FILED | Thursday, July 22, 2021 |
| APPL NO | 17/382786 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353898 | Hall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory W. Hall (Belmont, Massachusetts); Ian J. Gillerman (Somerville, Massachusetts); Sina Mohsenian (Billerica, Massachusetts); Aubrey Ortiz (Boston, Massachusetts); Christopher Miles (Acton, Massachusetts); Wolfgang Scholz (Beverly, Massachusetts); Adam J. Young (Dedham, Massachusetts); Benjamin Apollonio (Lunenburg, Massachusetts); Ziad F. Elghazzawi (Newton, Massachusetts) |
| ABSTRACT | Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/331793 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/12 (20130101) Original (OR) Class A61M 16/024 (20170801) A61M 2202/0275 (20130101) A61M 2205/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353940 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hubert H. Lim (Minneapolis, Minnesota); Craig D. Markovitz (Minneapolis, Minnesota); Sarah J. Offutt (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides methods for treating a neurological disorder or deficit, such as tinnitus and phantom limb pain. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/174045 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/00 (20130101) A61F 11/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0236 (20130101) A61H 2201/0207 (20130101) A61H 2201/1604 (20130101) A61H 2205/027 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/361 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36038 (20170801) A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36082 (20130101) A61N 1/36096 (20130101) A61N 1/36167 (20130101) A61N 2/002 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) A61N 5/0622 (20130101) A61N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353955 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pulsethera, Inc. (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Ting Dong (Boston, Massachusetts); Jie Hui (Boston, Massachusetts); Ji-Xin Cheng (Newton, Massachusetts); Yifan Zhu (Allston, Massachusetts) |
| ABSTRACT | Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387579 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/208 (20130101) A61L 2101/02 (20200801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Original (OR) Class A61N 5/0616 (20130101) A61N 5/0624 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353967 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kai Yu (Pittsburgh, Pennsylvania); Xiaodan Niu (Pittsburgh, Pennsylvania); Bin He (Pittsburgh, Pennsylvania) |
| ABSTRACT | Specific parameter sets are provided that makes the transcranial focused ultrasound to selectively activate a certain neuronal type at cortical brain and enables the transcranial focused ultrasound to non-invasively induce long-term effects at deep brain. A type of ultrasound collimator with incidence angle control is designed and validated through acoustic field pressure mapping in order to target brain areas at different depths. Multi-elements transducer arrays are also used to achieve transmission of focused ultrasound. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/284244 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/256 (20210101) A61B 5/291 (20210101) A61B 5/369 (20210101) A61B 5/4836 (20130101) A61B 2562/046 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0026 (20130101) A61N 2007/0056 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353968 | Cancelos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Silvina Cancelos (Mayaguez, Puerto Rico); Manuel Rivera Bengochea (San Juan, Puerto Rico); Edwin Lopez Ramos (Hatillo, Puerto Rico); William Garcia (Mayaguez, Puerto Rico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Silvina Cancelos (Mayaguez, Puerto Rico); Manuel Rivera Bengochea (San Juan, Puerto Rico); Edwin Lopez Ramos (Hatillo, Puerto Rico); William Garcia (Mayaguez, Puerto Rico) |
| ABSTRACT | An acoustic technique designed to increase the gas-dissolution rate of a bubble in a liquid media is proposed. Increased gas-dissolution rate is achieved by increasing the bubble's surface-to-volume ratio via bubble fragmentation. This is achieved by attaching an electroacoustic transducer to the system or load in which bubbles travel and exciting the transducer at the frequency of resonance. The electric resonance of the transducer attached to the system corresponds in frequency to the mechanical resonance of the system or load which allows for achieving such state without the use of an internally placed hydrophone to certify the resonance state. The acoustic bubble fragmentation technique increased the dissolution rate 4 to 5 times of bubbles with initial diameters between 150 and 550 μm in distilled water and in medical grade saline solution. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/324046 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0004 (20130101) Separation B01D 19/0078 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354143 | Skala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Melissa C. Skala (Middleton, Wisconsin); Kayvan Samimi (Madison, Wisconsin); Emmanuel Contreras-Guzman (Madison, Wisconsin) |
| ABSTRACT | Systems and methods for classifying T cells by activation state are disclosed. The system includes a cell analysis pathway, a time-resolved autofluorescence decay spectrometer, a processor, and a non-transitory computer-readable memory. The memory is accessible to the processor and has stored thereon instructions. The instructions, when executed by the processor, cause the processor to: a) receive the time-resolved autofluorescence decay signal; b) compute at least a first phasor coordinate at a first frequency and a second phasor coordinate at a second frequency from the time-resolved autofluorescence decay signal, wherein the first and second frequency are different; and c) compute an activation prediction for the T cell using at least the first phasor coordinate and the second phasor coordinate. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322367 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/143 (20130101) B01L 2200/0652 (20130101) B01L 2300/0663 (20130101) B01L 2300/0864 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0087 (20130101) C12N 5/0636 (20130101) C12N 2521/00 (20130101) C12N 2529/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354360 | LENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (TORONTO, Canada); BETH ISRAEL DEACONESS MEDICAL CENTRE, INC. (BOSTON, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | LIAN LENG (LASALLE, Canada); STEPHANIE GRAINGER (STONEHAM, Massachusetts); ELLIOT L. CHAIKOF (NEWTON, Massachusetts); AXEL GUENTHER (TORONTO, Canada); DAVID MIRANDA NIEVES (SOMERVILLE, Massachusetts); SHASHI MALLADI (TORONTO, Canada); RICHARD CHENG (TORONTO, Canada) |
| ABSTRACT | Systems, devices and methods are provided for fabricating anisotropic polymer materials. According to various embodiments, a fluidic device is employed to distribute a polymer solution and a flow-confining solution in order to generate a layered flow, where the layered flow is formed such that a polymer liquid sheet is sheathed on opposing sides by flow-confining liquid sheets. The fluidic device includes first and second fluid conduits, where the first fluid conduit receives the layered flow. The second fluid conduit has a reduced height relative to the first fluid conduit, such that the layered flow is constricted as it flows through the second fluid conduit. The constriction formed by the second flow conduit causes hydrodynamic focusing, reducing the thickness of the polymer liquid sheet, and inducing molecular alignment and anisotropy within the polymer liquid sheet as it is hardened and as strain is applied during extrusion of the sheet. |
| FILED | Wednesday, March 24, 2021 |
| APPL NO | 17/211613 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/002 (20190201) B29C 48/08 (20190201) B29C 48/022 (20190201) B29C 48/28 (20190201) B29C 48/92 (20190201) B29C 48/2556 (20190201) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 5/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0661 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355079 | Slusher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Institute of Organic Chemistry and Biochemistry AS (Prague, Czech Republic) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Rana Rais (West Friendship, Maryland); Jan Vavra (Praha, Czech Republic); Tomas Tichy (Praha, Czech Republic); Pavel Majer (Sykesville, Maryland); Andrej Jancarik (Koprivnice, Czech Republic); Lukas Tenora (Kretin, Czech Republic) |
| ABSTRACT | Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/372899 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) Acyclic or Carbocyclic Compounds C07C 259/06 (20130101) Original (OR) Class C07C 259/08 (20130101) Heterocyclic Compounds C07D 317/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355084 | THAKUR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ganeshsingh A. THAKUR (Cambridge, Massachusetts); Sumanta GARAI (Jamaica Plain, Massachusetts) |
| ABSTRACT | Heteroaromatic compounds are provided which are allosteric modulators of the cannabinoid receptors and which are useful for the treatment of glaucoma, pain, neuropathic pain, post-traumatic stress disorder (PTSD), and neurodegenerative diseases such as Huntington's disease, Alzheimer's disease, Parkinson's disease, multiple sclerosis, and other diseases where cannabinoid receptors are involved. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/054056 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/06 (20180101) Heterocyclic Compounds C07D 209/12 (20130101) Original (OR) Class C07D 209/18 (20130101) C07D 401/04 (20130101) C07D 403/06 (20130101) C07D 409/04 (20130101) C07D 417/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355099 | AHMED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. AHMED (Pasadena, California); Robert H. GRUBBS (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336756 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355114 | Lindsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Darren W. Engers (Brentwood, Tennessee); Aaron M. Bender (Spring Hill, Tennessee) |
| ABSTRACT | Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 17/287442 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 405/10 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 413/10 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355154 | Viglianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin L. Viglianti (Ann Arbor, Michigan); Allen F. Brooks (Ann Arbor, Michigan); Peter J. H. Scott (Ypsilanti, Michigan); Stephen Thompson (Ann Arbor, Michigan); Stefan Verhoog (Ann Arbor, Michigan); Milton D. Gross (Ann Arbor, Michigan); Wade P. Winton (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are halogenated cholesterol analogues, including methods of making and using the same. Also provided are methods of making radiolabeled cholesterol analogues including admixing an epoxide with a fluorine-18 source under conditions to form a radiofluorinated cholesterol analogue. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/250891 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Steroids C07J 9/00 (20130101) Original (OR) Class C07J 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355170 | Whitehead et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Whitehead (Boulder, Colorado); Monica Kirby (Boulder, Colorado); Zachary Baumer (Boulder, Colorado); Matthew Bedewitz (Boulder, Colorado); Brian Petersen (Boulder, Colorado); Paul J. Steiner (Boulder, Colorado) |
| ABSTRACT | The invention relates to one or more mutations configured to stabilize the prefusion “up” protomer trimeric Spike protein from SARS-CoV-2. The inventive technology further relates to systems, methods, and compositions to display one or more proteins on the surface of a yeast cell. Specifically, in one embodiment the invention relates to systems, methods, and compositions to display one or more Spike protein from SARS-CoV-2 on the surface of a yeast cell, and more preferably a Spike protein from SARS-CoV-2 stabilized in its prefusion conformation on the surface of a yeast cell. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318719 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355175 | CHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zibo CHEN (Seattle, Washington); Scott BOYKEN (Seattle, Washington); Sherry BERMEO (Seattle, Washington); Robert A. LANGAN (Seattle, Washington); David BAKER (Seattle, Washington) |
| ABSTRACT | Disclosed herein are designed heterodimer proteins, monomeric polypeptides capable of forming heterodimer proteins, protein scaffolds including such polypeptides, and methods for using the heterodimer proteins and subunit polypeptides for designing logic gates. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 17/285033 |
| CURRENT CPC | Peptides C07K 14/435 (20130101) Original (OR) Class C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355192 | Bunick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Bunick (Cheshire, Connecticut); Alexander Hinbest (Hamden, Connecticut) |
| ABSTRACT | The present invention provides compositions and methods for treatment, prevention or reduction of skin disease or disorders. In one embodiment, the composition comprises a peptide derived from the SD67 or SD150 region of filaggrin. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 17/283315 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Peptides C07K 14/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355193 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KOREA (CENTER FOR DISEASE CONTROL AND PREVENTION) (Chungcheongbuk-do, South Korea); NIH Office of Tech Transfer (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hansaem Lee (Chungcheongbuk-do, South Korea); Janghoon Choi (Chungcheongbuk-do, South Korea); Sungsoon Kim (Chungcheongbuk-do, South Korea); Lingshu Wang (Bethesda, Maryland); Barney Graham (Bethesda, Maryland); John Mascola (Bethesda, Maryland) |
| ABSTRACT | The present invention relates to monoclonal antibodies for a spike protein of the Middle East respiratory syndrome coronavirus (MERS-CoV), and a use thereof. Particularly, monoclonal antibodies 77-A5, 77-A6, 90-A3, 90-A9, 90-B2, 90-B7, 90-C4, 90-E5, 90-E6, 90-F1 and 90-F2 according to the present invention have excellent attachment force with respect to a full-length spike protein of MERS-CoV and the Si domain of the protein, and, of the monoclonal antibodies, the monoclonal antibodies 90-F1, 90-E5, 90-E6, 90-F2, 77-A5 and 77-A6 have excellent attachment force with respect to an RBD antigen of MERS-CoV. Also, the antibodies 77-A5, 77-A6, 90-E5, 90-E6, 90-F1 and 90-F2 exhibit neutralizing capacity with respect to a MERS pseudovirus and MERS-CoV, and the antibodies 90-B2 and 90-B7 exhibit neutralizing capacity only with respect to MERS-CoV. Further, the monoclonal antibodies have a particular monomeric form, and have excellent stability and thus may be useful for treating or diagnosing MERS. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/641580 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355195 | Bornholdt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); Adimab, LLC (Lebanon, New Hampshire); Mapp Biopharmaceutical, Inc. (San Diego, California); The University of Texas at Austin (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary A. Bornholdt (Encinitas, California); Akaash Mishra (Austin, Texas); Laura M. Walker (Norwich, Vermont); Noel T. Pauli (Lebanon, New Hampshire); Daniel Maurer (Cambridge, Massachusetts); Kartik Chandran (Bronx, New York); Jens Maximilian Fels (Bronx, New York); Dafna Abelson (San Diego, California); Jason Scott McLellan (Austin, Texas); Jonathan R. Lai (Bronx, New York); Ariel Wirchnianski (Bronx, New York); Olivia Vergnolle (Bronx, New York) |
| ABSTRACT | Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308753 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355196 | ESSER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AstraZeneca UK Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | AstraZeneca UK Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Mark ESSER (Gaithersburg, Maryland); James STEINHARDT (Gaithersburg, Maryland); Patrick MCTAMNEY, II (Gaithersburg, Maryland); Yueh-Ming LOO (Gaithersburg, Maryland); Reena M. VARKEY (Gaithersburg, Maryland); Qun DU (Gaithersburg, Maryland); Saravanan RAJAN (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of making and selecting the same. The antibodies can be used, for example, in prophylaxis, post-exposure prophylaxis, or treatment of SARS-CoV-2 infection. The antibodies can also be used to detect SARS-CoV-2 infection in subject. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322137 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355199 | Barker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas H. Barker (Crozet, None); Leandro Moretti (Charlottesville, None); Lizhi Cao (Charlottesville, None); John Nicosia (Charlottesville, None) |
| ABSTRACT | Provided are antibodies that include amino acid sequences of SEQ ID NOs: 2, 4, and 6-12, or amino acid sequences that are about 95% identical thereto, and fragments thereof Also provided are scFv peptides that include a VH segment having a first amino acid sequence of amino acids 4-113 of any one of SEQ ID NOs: 2 and 8-12, a VL segment having a second amino acid sequence having amino acids 113-237 of SEQ ID NOs. 2 and 8-12, or both; nucleic acids encoding the same; methods for using the same to detect and/or target conformational states of FN in samples; methods for treating diseases and/or disorders and/or for meliorating at least one symptom of consequence of a disease or disorder associated with abnormal expression of a force-induced conformational state of FN in subjects; and methods for screening for compounds having selective binding activities for conformational states of FN. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/457393 |
| CURRENT CPC | Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/21 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/04 (20130101) C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355210 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Markus H. Frank (Cambridge, Massachusetts); Natasha Y. Frank (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates in part to the discovery of genes that are deregulated in cancer stem cells (e.g., melanoma stem cells). In some aspects, methods for treating individuals having melanoma are provided; the methods involve modulating (e.g., inducing, inhibiting, etc.) the activity of the cancer stem cell associated genes. In other aspects, cell surface genes that are upregulated in melanoma stem cells are targeted for the selective isolation, detection, and killing of cancer stem cells in melanoma. Other aspects of the invention relate to reagents, arrays, compositions, and kits that are useful for diagnosing and treating melanoma. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/435929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 51/1096 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/51 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/3513 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355214 | Larrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nepenthe Bioscience LLC (Sunnvale, California) |
| ASSIGNEE(S) | Nepenthe Bioscience LLC (Sunnyvale, California) |
| INVENTOR(S) | James Larrick (Sunnyvale, California); Bo Yu (Sunnyvale, California); Andrew Mendelsohn (Palo Alto, California); John C. Cambier (Denver, Colorado) |
| ABSTRACT | The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders. |
| FILED | Thursday, July 22, 2021 |
| APPL NO | 17/382821 |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355231 | LELLA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vijaya M. LELLA (Tyler, Texas); Usha R. PENDURTHI (Tyler, Texas); Jhansi L. MAGISETTY (Tyler, Texas) |
| ABSTRACT | An antibody, preferably a blocking antibody, and most preferably a monoclonal antibody (mAb), specific for human endothelial cell protein C receptor (EPCR) such as mAbs JRK 1494 or JRK 1535 is used to reduce or attenuate joint swelling, macrophage infiltration, iron deposition and/or blood vessel formation and to treat arthropathy in a hemophilic subject. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 17/273965 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4846 (20130101) A61K 2039/54 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Peptides C07K 16/2896 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355440 | CHOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| INVENTOR(S) | Stella CHOU (Bryn Mawr, Pennsylvania); Connie WESTHOFF (New York, New York) |
| ABSTRACT | Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/757815 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355441 | Slukvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madision, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor Slukvin (Verona, Wisconsin); Ho Sun Jung (Madison, Wisconsin) |
| ABSTRACT | The present invention provides methods of creating a population of hemogenic endothelial cells with arterial specification and enhanced T cell potential. The methods involve inducing the expression of a SOX17 transgene in human pluripotent stem cells starting at day 2 of differentiation. Stem cells that express the SOX17 transgene are also provided. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/323715 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 2501/26 (20130101) C12N 2501/125 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2501/2307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355465 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts); Vikram Pattanayak (Wellesley, Massachusetts) |
| ABSTRACT | Engineered CRISPR-Cas9 nucleases with improved specificity and their use in genomic engineering, epigenomic engineering, genome targeting, and genome editing. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/331883 |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/90 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) C12N 2800/22 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 201/01043 (20130101) C12Y 203/01048 (20130101) C12Y 301/00 (20130101) C12Y 305/01098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355481 | Lisowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leszek Lisowski (San Mateo, California); Mark A. Kay (Los Altos, California) |
| ABSTRACT | Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/239132 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14141 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101) C12N 2750/14152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355495 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); Sukhbir Kaur (Bethesda, Maryland); Chengyu Liu (Boyds, Maryland) |
| ABSTRACT | Described herein is the discovery that cancer stem cells (CSCs) can be induced to differentiate by altering CD47 signaling. Provided herein are methods and compositions for inducing differentiation of cancer stem cells, for instance irreversible differentiation, including methods of treating subjects with cancer such as breast cancer, colon cancer, lung cancer, ovarian cancer, or melanoma, and including metastatic as well as primary cancer. Also provided are methods for treating subjects with triple negative breast cancers involving forcing differentiation of bCSCs of the subjects through targeting of CD47. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346630 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Peptides C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0695 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/3233 (20130101) C12N 2320/32 (20130101) C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355522 | CHOUDHARY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (CAMBRIDGE, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (BOSTON, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit CHOUDHARY (Boston, Massachusetts); Kurt COX (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods are provided for the inhibition of the function of RNA guided endonucleases, including the identification and use of such inhibitors. Methods of identifying inhibitor compounds of RNA guided nucleases, assays for detecting nuclease activity and compounds for use therein are also provided. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 17/269995 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355530 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chao-ting Wu (Brookline, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin Richard Williams (Seattle, Washington) |
| ABSTRACT | Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/389257 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355545 | Velculescu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor E. Velculescu (Dayton, Maryland); Robert B. Scharpf (Baltimore, Maryland); Eniko Papp (Baltimore, Maryland); Dorothy Hallberg (Baltimore, Maryland); Dennis Slamon (Oakland, California); Gottfried Konecny (Oakland, California) |
| ABSTRACT | This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as being likely to respond to a particular cancer treatment, and, optionally, for treating the mammal, are provided. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 17/284948 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355552 | BUNDY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brigham Young University (Provo, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradley C. BUNDY (Provo, Utah); J. Porter HUNT (Provo, Utah) |
| ABSTRACT | Disclosed herein are biosensors, which may be made from cell lysates, purified enzymes, or a combination thereof, for testing for the presence of a pathogen, such as SARS-CoV-2. The biosensor may be used in the context of a paper-based test, such as a colorimetric COVID-19 test. Methods of using the biosensor are also disclosed. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/319845 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class C12Q 1/6825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356251 | So et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peter T. C. So (Boston, Massachusetts); Jeon Woong Kang (Melrose, Massachusetts); Hyung Min Kim (Seoul, South Korea) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter T. C. So (Boston, Massachusetts); Jeon Woong Kang (Melrose, Massachusetts); Hyung Min Kim (Seoul, South Korea) |
| ABSTRACT | Since the fat content of pork is a deciding factor in grading the quality of meat, the use of a noninvasive subcutaneous probe for real-time, in situ monitoring of the fat components is of importance to vendors and other interested parties. Fortunately, in situ, in vivo monitoring of subcutaneous fat can be accomplished with spatially offset Raman spectroscopy (SORS) using a fiber-optic probe. The probe acquires Raman spectra as a function of spatial offset. These spectra are used to determine the relative composition of fat-to-skin. The Raman intensity ratio varies disproportionately depending on the fat content, with variations in slope that are correlated to the thickness of the fat layer. Ordinary least square (OLS) regression using two components indicates that depth-resolved SORS spectra reflect the relative thickness of the fat layer. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/249932 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356434 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shigao Chen (Rochester, Minnesota); James F. Greenleaf (Rochester, Minnesota); Armando Manduca (Rochester, Minnesota); Daniel C. Mellema (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Matthew W. Urban (Rochester, Minnesota) |
| ABSTRACT | Methods for processing data acquired using ultrasound elastography, in which shear waves are generated in a subject using continuous vibration of the ultrasound transducer, are described. The described methods can effectively separate shear wave signals from signals corresponding to residual motion artifacts associated with vibration of the ultrasound transducer. The systems and methods described here also provide for real-time visualization of shear waves propagating in the subject. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/637349 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/42 (20130101) G01N 29/043 (20130101) Original (OR) Class G01N 29/46 (20130101) G01N 29/348 (20130101) G01N 29/0645 (20130101) G01N 2291/044 (20130101) G01N 2291/106 (20130101) G01N 2291/0422 (20130101) G01N 2291/02475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356455 | Ginty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David D. Ginty (Cambridge, Massachusetts); Nikhil Sharma (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides a newly conceived of platform for identifying novel pain and/or pruritus-inhibiting agents (e.g., small molecule compounds, peptides, antigen binding proteins (e.g., antibodies or antibody fragments) that are efficacious, safe, and non-addictive alternatives for pain and pruritus management in place of (or in some embodiments, in combination with) “first line” treatments, such as gabapentin, pregabalin, and opioids. The present disclosure also provides for a method of treating pain and/or a pruritus comprising administering a therapeutically effective amount of an agent that activates a Gai/o-coupled G-Protein Coupled Receptor (GPCR) that is selectively expressed in the nociceptor and/or pruriceptor neuron subtypes of the somatosensory neurons. The disclosure also provides a method of inhibiting a nociceptor and/or pruriceptor somatosensory neurons, comprising contacting the nociceptor and/or pruriceptor somatosensory neuron with an agonist of a G-Protein Coupled Receptor (GPCR) expressed on the nociceptor and/or pruriceptor somatosensory neuron. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322861 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356472 | Tuttle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Bane Tuttle (Vestal, New York); Kamalika Mukherjee (Binghamton, New York) |
| ABSTRACT | Oxidative stress (OS) is associated with a wide variety of diseases and disorders. Detection of oxidative stress in living systems typically relies on fluorescent probes for reactive oxygen species (ROS), which is challenging because of their short life span and high reactivity. OS-induced biomolecule carbonylation is a stable modification that also possesses a chemically reactive functional group, and may be detected with a hydrazine, alkoxyamine or hydrazide-containing probe, in a hydrazone or oxime-forming reaction, that does not require strong acid catalysis or nucleophilic catalysis with an aromatic amine. Fluorophores possessing hydrazine, alkoxyamine or hydrazide functional groups can undergo reaction with carbonylated biomolecules in live cells, fixed cells, and tissue sample, and these products can be observed using fluorescence microscopy. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/321088 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/5014 (20130101) G01N 33/57496 (20130101) G01N 2021/6439 (20130101) G01N 2201/06113 (20130101) G01N 2800/709 (20130101) G01N 2800/7009 (20130101) G01N 2800/7042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356473 | ANSLYN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric ANSLYN (Austin, Texas); Edward MARCOTTE (Austin, Texas); Cecil J. HOWARD, II (Austin, Texas); Jagannath SWAMINATHAN (Austin, Texas); Angela M. BARDO (Austin, Texas); Brendan M. FLOYD (Austin, Texas); James REUTHER (Lowell, Massachusetts) |
| ABSTRACT | Provided herein are rapid and reversible methods to non-specifically immobilize peptides and proteins irrespective of their sequence, as well as small molecules, on a solid support to allow for manipulations of and reactions with these molecules in a manner that does not require purification between steps, which increases sample yield and reduces the quantity of starting material required. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282976 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) B01J 20/0229 (20130101) Peptides C07K 1/042 (20130101) C07K 17/06 (20130101) C07K 17/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6824 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356480 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana); Christina Ramires Ferreira (West Lafayette, Indiana); Allison Lisa Dill (Indianapolis, Indiana); Demian R. Ifa (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/331264 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0036 (20130101) H01J 49/142 (20130101) H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357042 | BORODIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anatoliy BORODIN (Setauket, New York); Yevgen BORODIN (Port Jeff Station, New York); Andrii SOVIAK (Lake Grove, New York) |
| ABSTRACT | Provided are a computer mouse and a method for operating the computer mouse, with the computer mouse including a palm-rest on a first side thereof, a baseplate on a second side substantially opposite the first side, hinges positioned along an edge of the palm-rest, and finger-rests, with each finger-rest fixedly attached to one end of a respective hinge. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 17/265296 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/03543 (20130101) Original (OR) Class G06F 2203/0333 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357630 | Shaevitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Joshua W. Shaevitz (Princeton, New Jersey); Mala Murthy (Princeton, New Jersey); Talmo D. Pereira (Princeton, New Jersey); Diego E. Aldarondo (Somerville, Massachusetts) |
| ABSTRACT | Disclosed are a system and method for quantifying changes in animal posture from video recordings of multiple interacting animals. Also disclosed are a system and method for training a posture identification algorithm efficiently with minimal human effort and evaluating the posture of millions of animal images. The disclosed process employs video recordings of behaving animals to produce a full set of geometrical coordinates for each body part over time. Inter alia, the disclosed system should be useful for organizations interested in doing large small-molecule screens to find drugs that affect the behavior of animals, and for those investigating new behavioral diagnostics for human patients. The disclosed system allows one to record video of animals and then automatically calculate the position of each body part over time. The output of this calculation can be used for simple analysis of the amount of movement for specific body parts, or part of a more complex scheme for measuring behaviors. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282818 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04845 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) Original (OR) Class G06K 9/00744 (20130101) G06K 9/6223 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 2207/10016 (20130101) G06T 2207/20101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358573 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Johanna Klughammer (Cambridge, Massachusetts); Daniel Abravanel (Boston, Massachusetts) |
| ABSTRACT | The present invention discloses novel methods and uses thereof for producing molecular spatial maps of metastatic breast cancer (MBC) and ductal carcinoma in situ of the breast (DCIS). A specific list of genes are identified using single-cell RNA sequencing and single-nucleus RNA sequencing and are used for RNA visualization of MBC and DCIS tissue microenvironment. Unexpected subtypes of tumor cells are revealed, and methods for identifying molecular biomarkers for MBC in the bone and breast and DCIS are disclosed. Furthermore, methods for identifying therapeutic agents and uses thereof for treating MBC and DCIS as well as compositions thereof comprising such identified therapeutic agents are provided. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/156392 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 45/00 (20190201) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358574 | Getz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Gad Getz (Boston, Massachusetts); Amaro Taylor-Weiner (Cambridge, Massachusetts); Francois Aguet (Cambridge, Massachusetts) |
| ABSTRACT | The disclosure relates to methods for increasing the speed and efficiency of computational genomics. In particular, the disclosure relates to methods of scaling computational genomics by using one or more specialized architectures for highly parallelized computations, such as graphics processing units (GPUs), tensor processing units (TPUs), and field programmable gate arrays (FPGAs), and the like, to compute the computational genomics calculations. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 17/284708 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 50/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358627 | Longmire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Medable Inc. (Palo Alto, California) |
| ASSIGNEE(S) | Medable Inc. (PALO ALTO, California) |
| INVENTOR(S) | Michelle Longmire (PALO ALTO, California); Ingrid Oakley-Girvan (Henderson, California); NICK MOSS (Los Alamos, New Mexico) |
| ABSTRACT | A method and system for connecting, capturing, managing and predicting outcomes for an improved care for home based patients by collecting data from caregivers and home-based patients. The method and system implemented as a mobile technology is more efficient and effective method for delivering healthcare that will ease the caregiving burden. Providing resources and information to communicate, capture and deliver by the caregivers (formal and informal), patients and healthcare providers communicate helps integrate essential data and care. Through the use of this mobile technology and associated devices vital information from informal caregivers, which is currently not regularly used in remotely located patients, can be captured and implemented in the decisions and adjustments to patients' care plans. In addition, the technology helps with adherence of patient specific treatment guidelines for home-based patients. |
| FILED | Sunday, March 14, 2021 |
| APPL NO | 17/200866 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 10/65 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 80/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358629 | Wujek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Thaddeus Wujek (Milwaukee, Wisconsin); Kathleen Marie Schmainda (Elm Grove, Wisconsin) |
| ABSTRACT | Systems and methods are described for segmenting medical images, such as magnetic resonance images, using a deep learning model that has been trained using random dropped inputs, standardized inputs, or both. Medical images can be segmented based on anatomy, physiology, pathology, other properties or characteristics represented in the medical images, or combinations thereof. As one example, multi-contrast magnetic resonance images are input to the trained deep learning model in order to generate multiple segmented medical images, each representing a different segmentation class. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/284715 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/143 (20170101) G06T 2207/10088 (20130101) G06T 2207/20084 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358642 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Laurent Audoly (, None); Vanderbilt University (Nashville, Tennessee); Parthenon Therapeutics, Inc. (Brookline, Massachusetts); DUET Biosystems, Inc. (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian T. Meyer (Nashville, Tennessee); Vito Quaranta (Nashville, Tennessee); Leonard A. Harris (Nashville, Tennessee); Buddhi Bishal Paudel (Nashville, Tennessee); David J. Wooten (Nashville, Tennessee); Laurent Audoly (Brookline, Massachusetts) |
| ABSTRACT | The invention provides methods for evaluating the therapeutic benefit of a combination therapy useful for treating a medical disorder, such as cancer. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180280 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 70/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20210353298 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Timothy K Williams (Winston-Salem, North Carolina); Lucas Paul Neff (Winston-Salem, North Carolina) |
| ABSTRACT | An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304). |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318549 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1204 (20130101) A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12136 (20130101) A61B 2017/1205 (20130101) A61B 2090/061 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) A61M 25/0097 (20130101) A61M 29/02 (20130101) A61M 2025/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353504 | Schulz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIERRA NEVADA CORPORATION (Sparks, Nevada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karl Schulz (Sparks, Nevada); Richard Campbell (Sparks, Nevada); Emily Huang (Sparks, Nevada); Sarah Koh (Sparks, Nevada); Kurnhee Ma (Sparks, Nevada) |
| ABSTRACT | Mobile systems and methods are adapted to control and document prehospital patient care reports and communication of patient status to a receiving medical treatment facility. The systems and methods relate to systems and methods for managing, recording, and administering drugs such as narcotics in an ambulatory and/or emergency environment. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339588 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 50/22 (20160201) A61B 50/31 (20160201) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 7/0069 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353585 | LAMMERDING et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan LAMMERDING (Ithaca, New York); Tyler J. KIRBY (Brooktondale, New York); Gregory R. FEDORCHAK (Ithaca, New York); Ashley J. EARLE (Dryden, New York) |
| ABSTRACT | The present application relates to methods of treating a laminopathy affecting skeletal or cardiac muscle in a subject. The methods involve selecting a subject who has a laminopathy affecting skeletal or cardiac muscle. In some embodiments, the methods involve administering, to the selected subject, an inhibitor of a protein associated with a DNA damage response (DDR) pathway to treat the laminopathy affecting skeletal or cardiac muscle in the subject. In other embodiments, the methods involve administering, to the selected subject, a microtubule stabilizing agent and a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor to treat the laminopathy affecting skeletal or cardiac muscle in the subject. Also disclosed are pharmaceutical compositions comprising an inhibitor of a protein associated with a DNA damage response (DDR) pathway, a microtubule stabilizing agent, and/or a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 17/274131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353781 | Veiseh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omid Veiseh (Bellaire, Texas); Volkan Yesilyurt (Watertown, Massachusetts); Andrew Bader (Charlestown, Massachusetts); Whitney Loo (Berkeley, California); Daniel G. Anderson (Framingham, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Surface-modified cell containing a cell and a conformal coating on the extracellular surface of the cell are described. The conformal coating contains two or more layers containing particles (e.g. nanoparticles) or macromolecules. The cell is an islet cell, a B cell, or a T cell. The macromolecules or particles are formed from zwitterionic polymers. Covalent linkages are employed to link the particles or macromolecules to a cell surface molecule containing an abiotic functional group, or between macromolecules and/or particles in adjacent layers. Also described are methods of making and using a surface-modified cell. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 17/278383 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6933 (20170801) A61K 49/1854 (20130101) Original (OR) Class A61K 49/1878 (20130101) A61K 49/1896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353896 | Reeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Reeh (College Station, Texas); Mahesh Waje (College Station, Texas); Mehmet Kesmez (College Station, Texas); Carlos Salinas (Bryan, Texas); Jibi Varughese (College Station, Texas); John Zbranek (College Station, Texas); Seth Cocking (College Station, Texas); Ashwin Balasubramanian (College Station, Texas); Cory Teurman (College Station, Texas); James Netherland (Bryan, Texas); Geoffrey Duncan Hitchens (Allen, Texas) |
| ABSTRACT | The present invention includes a device for hypoxia training comprising: one or more electrochemical cells each comprising: a cathode and an anode separated by a proton exchange membrane, each of the anode and cathode in communication with an input and an output, wherein the input of the cathode is in fluid communication with ambient air, and wherein the input of the anode is in fluid communication with a source of liquid water; a power supply connected to the one or more electrochemical cells; and a mask in fluid communication with the output from the cathode of the one or more electrochemical cells, wherein oxygen is removed from the ambient air during contact with the cathode when hydrogen ions separated from liquid water by a catalyst on the anode convert oxygen in the ambient air into water. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353470 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) Original (OR) Class A61M 16/12 (20130101) A61M 16/22 (20130101) A61M 16/0045 (20130101) A61M 16/101 (20140204) A61M 16/106 (20140204) A61M 16/202 (20140204) A61M 16/209 (20140204) A61M 16/1085 (20140204) A61M 2016/1025 (20130101) A61M 2202/0208 (20130101) Devices, Apparatus or Methods for Life-saving A62B 7/14 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 23/18 (20130101) A63B 2220/56 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/085 (20130101) G09B 9/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353923 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chi Hwan Lee (West Lafayette, Indiana); Dong Rip Kim (Seoul, South Korea) |
| ABSTRACT | Devices for intracellular and intratissue nanoinjection of biomolecules into a living body and methods of producing the devices. Such a device includes a flexible substrate and nanoneedles extending from a surface of the flexible substrate, and can be produced by providing a first substrate having pillars extending from a surface thereof, locally reducing diameters of the pillars at locations thereof adjacent the first substrate, embedding distal ends of the pillars in a flexible substrate, and sufficiently expanding the flexible substrate to cause the pillars to fracture at the locations thereof adjacent the first substrate and detach therefrom to define nanoneedles extending from the flexible substrate. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/277427 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) A61M 2205/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354139 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William P. King (Champaign, Illinois); Rashid Bashir (Champaign, Illinois); Mehmet Y. Aydin (Urbana, Illinois); Jacob E. Berger (Champaign, Illinois); Enrique Valera (Champaign, Illinois) |
| ABSTRACT | A microfluidic diagnostic device with a three-dimensional (3D) flow architecture comprises a polymeric body having first and second opposing surfaces and comprising first flow channels in the first opposing surface, second flow channels in the second opposing surface, and connecting flow passages extending through a thickness of the polymeric body to connect the first flow channels to the second flow channels, thereby defining a continuous 3D flow pathway in the polymeric body. The microfluidic diagnostic device also includes a first cover adhered to the first opposing surface to seal the first flow channels, a second cover adhered to the second opposing surface to seal the second flow channels, and one or more access ports in fluid communication with the continuous 3D flow pathway for introducing liquid reagent(s) and/or a sample into the polymeric body. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/316900 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502738 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 2200/10 (20130101) B01L 2300/087 (20130101) B01L 2300/0681 (20130101) B01L 2300/0887 (20130101) B01L 2400/049 (20130101) B01L 2400/0478 (20130101) B01L 2400/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354144 | SHENG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian SHENG (College Station, Texas); Andrew R. WHITE (College Station, Texas); Maryam JALALI (College Station, Texas) |
| ABSTRACT | The present disclosure relates to a microfluidic channel composition configured for establishing a liquid-liquid interface and a microfluidic platform comprising the microfluidic channel composition. More particularly, the present disclosure includes a microfluidic platform for analyzing oil-aqueous interface interactions and methods utilizing the platform, for instance to evaluate environmental settings where oil may be present. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318763 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2300/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354540 | FLAXMAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QinetiQ Limited (Hampshire, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert John Bonner FLAXMAN (Guildford, United Kingdom) |
| ABSTRACT | Some embodiments are directed to a drive configuration for a skid-steered vehicle that has a pair of traction motors for rotationally driving opposite outputs of the drive configuration. The traction motors are operatively connected to the outputs via respective gearing arrangements for selectively varying gear reduction between each of the traction motors and the corresponding output. The drive configuration also has a steer differential in a torque connection with the first and second outputs of the drive configuration. The drive configuration additional has a steer motor operatively connected to the steer differential for selectively varying the rotational speed of the first and second outputs in use. Also, the traction and steer motors define a volume in which the gearing arrangements and steering differential are at least partially located. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/390522 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 1/02 (20130101) Original (OR) Class B60K 6/445 (20130101) B60K 17/08 (20130101) B60K 17/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354571 | Bloomstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Theodore Bloomstein (Medford, Massachusetts) |
| ABSTRACT | An underwater liquid supply unit includes a first bladder containing a first liquid, a second bladder containing a second liquid, and a third bladder containing a third liquid. The combined volume of the first liquid, second liquid, and third liquid is neutrally buoyant relative to a surrounding medium the liquid supply unit is disposed in (e.g., in seawater). As the first liquid, second liquid, and third liquid are dispensed from the bladders, the bladders may reduce in size in at least one dimension. As the liquids are dispensed, the liquids may be dispensed in a predetermined volumetric ratio based on the density of the liquids to maintain neutral buoyancy of the combined volume of liquid. The underwater liquid supply unit may also include an integrated generator such as a fuel cell, as well as a propeller. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 15/930376 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/75 (20190201) Original (OR) Class B60L 2200/32 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04201 (20130101) H01M 16/006 (20130101) H01M 2220/20 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354812 | Patterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Patterson (Hudson, New Hampshire); Mark Silver (Bedford, Massachusetts) |
| ABSTRACT | An aerial vehicle with a plurality of selectively collapsible arms capable of transitioning between an extended state and a contracted state is described. In the extended position, the distance between the main body of the vehicle and the rotor associated with each arm is maximized. In the contracted state, the distance between the main body of the vehicle and the rotor associated with each arm is minimized. In certain embodiments, each of the arms may include one or more tape springs that are biased to selectively move the associated one or more rotors of each arm between the retracted and extended states. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/196102 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/33 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355060 | SRIDHAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jayalakshmi SRIDHAR (New Orleans, Louisiana); Frank JONES (New Orleans, Louisiana); Cheryl STEVENS (Bowling Green, Kentucky) |
| ABSTRACT | The present disclosure relates to compounds that act as protein kinase inhibitors, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 17/284432 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 50/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355073 | SUN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shouheng SUN (East Greenwich, Rhode Island); Mengqi SHEN (Providence, Rhode Island); Hu LIU (Providence, Rhode Island) |
| ABSTRACT | The instant invention provides processes for a chemo selective reduction of a nitro group within a compound in the presence of other groups which can also be reduced. This aspect of the present invention provides an ammonia borane (AB) initiated chemoselective reduction process of a nitro group contained within a compound in the presence of a copper (Cu) nanoparticle based catalyst. The invention is also directed to Copper (Cu) nanoparticle (NP) based catalysts, selected from Cu/WOx, Cu/SiO2, and Cu/C; wherein x represents an integer having a value of from about 2 to about 3.5, used in the chemo selective reduction of a nitro group contained within a compound in the presence of other groups which can also be reduced. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/293581 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/888 (20130101) B01J 35/026 (20130101) Acyclic or Carbocyclic Compounds C07C 209/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355099 | AHMED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. AHMED (Pasadena, California); Robert H. GRUBBS (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336756 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355161 | Stikeleather |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ryan Stikeleather (Phoenix, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Ryan Stikeleather (Phoenix, Arizona) |
| ABSTRACT | Methods and systems for automated protein purification are disclosed. The disclosed methods and systems utilize a plurality of magnetic bead chemistries and an automated extraction system for the purification of one or more proteins within a short time frame. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242973 |
| CURRENT CPC | Peptides C07K 1/22 (20130101) C07K 1/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355196 | ESSER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AstraZeneca UK Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | AstraZeneca UK Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Mark ESSER (Gaithersburg, Maryland); James STEINHARDT (Gaithersburg, Maryland); Patrick MCTAMNEY, II (Gaithersburg, Maryland); Yueh-Ming LOO (Gaithersburg, Maryland); Reena M. VARKEY (Gaithersburg, Maryland); Qun DU (Gaithersburg, Maryland); Saravanan RAJAN (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of making and selecting the same. The antibodies can be used, for example, in prophylaxis, post-exposure prophylaxis, or treatment of SARS-CoV-2 infection. The antibodies can also be used to detect SARS-CoV-2 infection in subject. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322137 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355329 | Walters et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David N. Walters (Slippery Rock, Pennsylvania); John R. Schneider (Sharpsburg, Pennsylvania) |
| ABSTRACT | Coating compositions are disclosed that include corrosion resisting particles such that the coating composition can exhibit corrosion resistance properties. Also disclosed are substrates at least partially coated with a coating deposited from such a composition and multi-component composite coatings, wherein at least one coating later is deposited from such a coating composition. Methods and apparatus for making ultrafine solid particles are also disclosed. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234459 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 283/006 (20130101) C08F 290/06 (20130101) C08F 299/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/672 (20130101) C08G 18/3206 (20130101) Compositions of Macromolecular Compounds C08L 23/26 (20130101) C08L 27/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) C09D 5/002 (20130101) C09D 5/084 (20130101) Original (OR) Class C09D 7/67 (20180101) C09D 123/26 (20130101) C09D 175/16 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/258 (20150115) Y10T 428/31522 (20150401) Y10T 428/31529 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355331 | Droege et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ocellus, Inc. (Livermore, California) |
| ASSIGNEE(S) | Ocellus, Inc. (Livermore, California) |
| INVENTOR(S) | Michael Droege (Livermore, California); Shannon Downey (San Lorenzo, California); Lawrence Hrubesh (Pleasanton, California) |
| ABSTRACT | This invention relates to coating compositions for thermal protection of substrates (particularly for protecting surfaces that are subject to transient, extreme temperature excursions), processes for manufacturing the coating and methods for applying them. The coating is designed to reduce/minimize the thermal diffusivity of the composite and uses constituent materials selected from groups of inorganic fibers, hollow microspheres, aerogels, and inorganic binders. Thermal diffusivity can be reduced/minimized by controlling the relative concentrations of the coating components. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170588 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/24 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 5/18 (20130101) Original (OR) Class C09D 7/61 (20180101) C09D 7/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355522 | CHOUDHARY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (CAMBRIDGE, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (BOSTON, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit CHOUDHARY (Boston, Massachusetts); Kurt COX (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods are provided for the inhibition of the function of RNA guided endonucleases, including the identification and use of such inhibitors. Methods of identifying inhibitor compounds of RNA guided nucleases, assays for detecting nuclease activity and compounds for use therein are also provided. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 17/269995 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355985 | Stupp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRC, Inc. (North Syracuse, New York) |
| ASSIGNEE(S) | SRC, Inc. (North Syracuse, New York) |
| INVENTOR(S) | Andrew H. Stupp (Syracuse, New York) |
| ABSTRACT | An accessory for tethering a cap for a SMA/SMP bulkhead to a device assembly without having to introduce elements that could compromise the integrity of the device assembly. The accessory includes a first portion that engages the SMA/SMP bulkhead and securely interconnects thereto, and a second portion that includes an opening where a tether chain is physically interconnected thereto. The tether chain includes the cap for the SMA/SMP bulkhead secured to the second end thereof. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875387 |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 41/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356243 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| INVENTOR(S) | Anthony Shaw (Madison, New Jersey); Jay Poret (Sparta, New Jersey); Lori Groven (Rapid City, South Dakota); Joshua Koenig (Rapid City, South Dakota); Jason Brusnahan (Semaphore Park, Australia) |
| ABSTRACT | The present invention is a pyrotechnic time delay system that is improved over prior-art designs. Specifically, the system described herein comprises at least one delay element. The delay element or delay elements each have an input charge, a delay composition, and an output charge. Both the input charge and the output charge are igniter compositions and are comprised of the same components despite having different functional goals. The input charge and output charge compositions preferably contain titanium, manganese dioxide, and polytetrafluoroethylene. The delay composition may be modified from current formulations to include manganese and manganese dioxide, or tungsten and manganese dioxide. The system disclosed herein may be comprised of one delay element, or it may be modular wherein multiple delay elements are connected in series. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389598 |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/00 (20130101) C06B 33/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 5/00 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 9/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356306 | Parziale |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Nick Parziale (Ridgewood, New Jersey) |
| ABSTRACT | Methods and apparatus for tracking fluid flows are disclosed. Fast-moving fluids can be non-invasively tracked, including those at supersonic and hypersonic speeds. To track such flows, atoms of an inert gas can be introduced into the fluid. To monitor the tracer, a laser excites a series of molecules along a “write line,” which can be tracked by a series of cameras in order to estimate flow velocity. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/320112 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/704 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/248 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356435 | Pantea et al. |
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| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cristian Pantea (Los Alamos, New Mexico); John James Greenhall (Santa Fe, New Mexico); Alan Lyman Graham (Los Alamos, New Mexico); Dipen N. Sinha (Bay Shore, New York) |
| ABSTRACT | Techniques are provided for detecting wafer defects. Example techniques include exciting a wafer using an acoustic signal to cause the wafer to exhibit vibrations, measuring one or more of linear frequency response metrics or nonlinear frequency responses metrics associated with the vibrations, and identifying any defects in the wafer based at least in part on one or more of the linear frequency response metrics or nonlinear frequency responses metrics. In embodiments, the wafer includes bismuth telluride (Bi2Te3). |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/321332 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/12 (20130101) Original (OR) Class G01N 29/27 (20130101) G01N 29/46 (20130101) G01N 29/225 (20130101) G01N 29/2418 (20130101) G01N 29/2437 (20130101) G01N 2291/011 (20130101) G01N 2291/023 (20130101) G01N 2291/101 (20130101) G01N 2291/0289 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356492 | Kozacik et al. |
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| FUNDED BY |
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| APPLICANT(S) | EM Photonics, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Kozacik (Bloomfield, New Jersey); Aaron Paolini (Wilmington, Delaware); Eric Kelmelis (Lincoln University, Pennsylvania) |
| ABSTRACT | An apparatus for determining wind speed includes an image capture device, a memory, and a computer-readable medium. The image capture device captures video and the memory stores the video. The computer-readable medium includes a computer program product stored thereon, and the computer program product is configured to determine a wind speed in the scene based on analysis of atmospheric turbulence occurring in the video. The method may include comparing a set of models to an analyzed video to determine the wind speed. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/201851 |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/26 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) Image Data Processing or Generation, in General G06T 2207/30212 (20130101) G06T 2207/30232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356611 | Nelson |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle Alan Nelson (San Diego, California) |
| ABSTRACT | A sensor for spectroscopic measurement of alpha and beta particles includes first and second layers, a photomultiplier, and an analyzer. A first material of the first layer scintillates a first stream of photons for each of the alpha particles. However, the beta particles pass through the first layer. A second material of the second layer scintillates a second stream of photons for each of the beta particles, but passes the first stream of photons for each alpha particle. The photomultiplier amplifies the first and second streams of photons for the alpha and beta particles into an electrical signal. The electrical signal includes a respective pulse for each of the alpha and beta particles. From the electrical signal, the analyzer determines a respective energy of each of the alpha and/or beta particles from a shape of the respective pulse for each of the alpha and beta particles. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 15/930117 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/362 (20130101) Original (OR) Class G01T 1/20181 (20200501) G01T 1/20184 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356951 | Matei et al. |
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| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ion Matei (Sunnyvale, California); Jeng Ping Lu (Fremont, California); Saigopal Nelaturi (Mountain View, California); Julie A. Bert (East Palo Alto, California); Lara S. Crawford (Belmont, California); Armin R. Volkel (Mountain View, California); Eugene M. Chow (Palo Alto, California) |
| ABSTRACT | The system and method described allow for real-time control over positioning of a micro-object. A movement of at least one micro-object suspended in a medium can be induced by a generation of one or more forces by electrodes proximate to the micro-object. Prior to inducing the movement, a simulation is used to develop a model describing a parameter of an interaction between each of the electrodes and the micro-object. A function describing the forces generated by an electrode and an extent of the movement induced due to the forces is generated using the model. The function is used to design closed loop policy control scheme for moving the micro-object towards a desired position. The position of the micro-object is tracked and taken into account when generating voltage patterns in the scheme. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391381 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 17/02 (20130101) G05B 19/41885 (20130101) Original (OR) Class G05B 2219/32359 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) G06T 7/155 (20170101) G06T 7/194 (20170101) G06T 2207/20021 (20130101) G06T 2207/30164 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357328 | ABED et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jackson State University (Jackson, Mississippi) |
| ASSIGNEE(S) | Jackson State University (Jackson, Mississippi) |
| INVENTOR(S) | Khalid ABED (Madison, Mississippi); Tirumale RAMESH (Chantilly, Virginia) |
| ABSTRACT | Embodiments of a system for dynamic reconfiguration of cache are disclosed. Accordingly, the system includes a plurality of processors and a plurality of memory modules executed by the plurality of processors. The system also includes a dynamic reconfigurable cache comprising of a multi-level cache implementing a combination of an L1 cache, an L2 cache, and an L3 cache. The one or more of the L1 cache, the L2 cache, and the L3 cache are dynamically reconfigurable to one or more sizes based at least in part on an application data size associated with an application being executed by the plurality of processors. In an embodiment, the system includes a reconfiguration control and distribution module configured to perform dynamic reconfiguration of the dynamic reconfigurable cache based on the application data size. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872409 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/121 (20130101) G06F 12/0811 (20130101) Original (OR) Class G06F 2212/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357585 | Surdeanu et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mihai Surdeanu (Tucson, Arizona); Marco A. Valenzuela Escarcega (Tucson, Arizona); Gustave Hahn-Powell (Tucson, Arizona); Dane Bell (Tucson, Arizona); Thomas Hicks (Tucson, Arizona); Enrique Noriega (Tucson, Arizona); Clayton Morrison (Tucson, Arizona); Rebecca Sharp (Tucson, Arizona); Robert Ionut Vacareanu (Botosani, Romania); George Barbosa (Tucson, Arizona) |
| ABSTRACT | A machine reading system is described herein that includes a framework in which grammar rules can be developed using a concise language that combines syntax and semantics. The resulting technology thus reduces the development time for new grammars in a new domain. An enormous amount of information appears in the form of natural language across millions of academic papers and other literature sources. For example, in the biological domain, there is a tremendous ongoing effort to extract individual chemical interactions from these texts, but these interactions are only isolated fragments of larger causal mechanisms such as protein signaling pathways. The proposed rule-based event extraction framework can model underlying syntactic representations of events in order to extract signaling pathway fragments. Though application to the biomedical domain is herein described, the framework is domain-independent and is expressive enough to capture most complex events annotated by domain experts. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 17/344774 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 16/245 (20190101) G06F 40/30 (20200101) G06F 40/169 (20200101) G06F 40/211 (20200101) Original (OR) Class G06F 40/253 (20200101) G06F 40/284 (20200101) G06F 40/295 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357648 | METAXAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dimitris METAXAS (New Brunswick, New Jersey); Zachary A. DANIELS (New Brunswick, New Jersey) |
| ABSTRACT | An image processing neural network system includes a base net of at least one convolutional layer and at least one pooling layer; and a scenario block layer. The scenario block layer performs scene classification and generates a dictionary of scenarios and a vector of scenario encoding coefficients to output a probabilistic scene class assignment and the vector of scenario encoding coefficients. The vector of scenario encoding coefficients corresponds to reasoning for the scene classification. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/790641 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00718 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357729 | Leino et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Klas Leino (Pittsburgh, Pennsylvania); Shayak Sen (Pittsburgh, Pennsylvania); Anupam Datta (Palo Alto, California); Matthew Fredrikson (Pittsburgh, Pennsylvania) |
| ABSTRACT | A computing machine accesses a set of intermediate artificial neurons in a deep neural network. The deep neural network is fully or partially trained. The computing machine computes, for each artificial neuron in the set of intermediate artificial neurons, an influence score based on an average gradient of an output quantity of interest with respect to the artificial neuron across a plurality of inputs weighted by a probability of each input. The computing machine provides an output associated with the computed influence scores. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583392 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0472 (20130101) Original (OR) Class G06N 3/0481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357737 | Hamerly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ryan Hamerly (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Hamerly (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Deep learning performance is limited by computing power, which is in turn limited by energy consumption. Optics can make neural networks faster and more efficient, but current schemes suffer from limited connectivity and the large footprint of low-loss nanophotonic devices. Our optical neural network architecture addresses these problems using homodyne detection and optical data fan-out. It is scalable to large networks without sacrificing speed or consuming too much energy. It can perform inference and training and work with both fully connected and convolutional neural-network layers. In our architecture, each neural network layer operates on inputs and weights encoded onto optical pulse amplitudes. A homodyne detector computes the vector product of the inputs and weights. The nonlinear activation function is performed electronically on the output of this linear homodyne detection step. Optical modulators combine the outputs from the nonlinear activation function and encode them onto optical pulses input into the next layer. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/681284 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/0675 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357742 | RESTUCCIA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francesco RESTUCCIA (Boston, Massachusetts); Tommaso MELODIA (Newton, Massachusetts) |
| ABSTRACT | Apparatuses and methods for real-time spectrum-driven embedded wireless networking through deep learning are provided. Radio frequency, optical, or acoustic communication apparatus include a programmable logic system having a front-end configuration core, a learning core, and a learning actuation core. The learning core includes a deep learning neural network that receives and processes input in-phase/quadrature (I/Q) input samples through the neural network layers to extract RF, optical, or acoustic spectrum information. A processing system having a learning controller module controls operations of the learning core and the learning actuation core. The processing system and the programmable logic system are operable to configure one or more communication and networking parameters for transmission via the transceiver in response to extracted spectrum information. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/591772 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/063 (20130101) Wireless Communication Networks H04W 24/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357858 | MEHTA |
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| FUNDED BY |
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| APPLICANT(S) | InspiRD, Inc. (Mission Viejo, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SANDEEP MEHTA (Redondo Beach, California) |
| ABSTRACT | Exemplary embodiments disclose a method, a computer program product, and a computer system for managing certification efforts for obtaining regulatory approvals to market products. Exemplary embodiments use the certification argument framework to structure complex certification efforts and build a database of related information. The certification argument framework also provides effective means of graphically representing and analyzing regulatory certification efforts. A computer-implemented method to certify a product or service includes creating a certification argument with one or more certification goals and linking the one or more certification goals to one or more evidences that support the one or more certification goals. The method includes linking the one or more evidences to one or more rationales that demonstrate a sufficiency of the one or more evidences and linking one or more tasks, that can generate the one or more evidences, to the certification argument. The method includes linking one or more contexts, for the one or more certification goals, to the certification argument and determining one or more relationships between the one or more certification goals, the one or more evidences, the one or more rationales, the one or more tasks, and the one or more contexts. The method includes utilizing the certification argument to evaluate a certification effort. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 15/930433 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/288 (20190101) G06F 30/10 (20200101) G06F 40/186 (20200101) G06F 2111/10 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Original (OR) Class G06Q 10/06316 (20130101) G06Q 30/0185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358651 | Bhattacharya et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mishkatul Bhattacharya (Rochester, New York); Anthony Nickolas Vamivakas (Rochester, New York) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); University of Rochester (Rochester, New York) |
| INVENTOR(S) | Mishkatul Bhattacharya (Rochester, New York); Anthony Nickolas Vamivakas (Rochester, New York) |
| ABSTRACT | An optical tweezer phonon laser system and method for modulating mechanical vibrations of an optically levitated mechanical oscillator to produce coherence is disclosed. A feedback loop is configured to simultaneously supply an electro-optic modulator with an amplification signal and a cooling signal representing an amplification force linear in the mechanical oscillator momentum and a cooling force nonlinear in the mechanical oscillator variable position and linear in the momentum, respectively controlling the intensity of a trap beam levitating the mechanical oscillator. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/320708 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/283 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0123 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359097 | Shinohara et al. |
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| FUNDED BY |
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| APPLICANT(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keisuke Shinohara (Thousand Oaks, California); Casey King (Newbury Park, California); Eric Regan (Moorpark, California) |
| ABSTRACT | An ohmic contact for a multiple channel FET comprises a plurality of slit-shaped recesses in a wafer on which a multiple channel FET resides, with each recess having a depth at least equal to the depth of the lowermost channel layer. Ohmic metals in and on the sidewalls of each recess provide ohmic contact to each of the multiple channel layers. An ohmic metal-filled linear connecting recess contiguous with the outside edge of each recess may be provided, as well as an ohmic metal contact layer on the top surface of the wafer over and in contact with the ohmic metals in each of the recesses. The present ohmic contact typically serves as a source and/or drain contact for the multiple channel FET. Also described is the use of a regrown material to make ohmic contact with multiple channels, with the regrown material preferably having a corrugated structure. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/877378 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/452 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/7783 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359099 | Shen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pin-Chun Shen (Changhua, Taiwan); Jing Kong (Winchester, Massachusetts) |
| ABSTRACT | Devices, such as transistors, that use bismuth to create ohmic contacts are provided, as are methods of manufacturing the same. The transistors, such as field-effect transistors, can include one or more two-dimensional materials, and electrical contact areas can be created on the two-dimensional material(s) using bismuth. The bismuth can help to provide energy-barrier free, ohmic contacts, and the resulting devices can have performance levels that rival or exceed state-of-the-art devices that utilize three-dimensional materials, like silicon. The two-dimensional materials can include transition metal dichalcogenides, such as molybdenum disulfide. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/320183 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/45 (20130101) H01L 29/4983 (20130101) Original (OR) Class H01L 29/66628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359531 | Couvillon et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ivan Couvillon (Lutherville, Maryland); Matthew Limpert (Bel Air, Maryland) |
| ABSTRACT | Various embodiments are described that relate to a battery. A battery, such as a battery with a common input/output terminal, can be tested. Part of this testing can include charging the battery and discharging the battery. It can be dangerous to switch out an interface between charging and discharging. Therefore, a single interface can be employed that enables the battery to be charged and discarded. With this, the battery can be charged and discharged without the danger of switching the interface. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/386596 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) Original (OR) Class H02J 7/0069 (20200101) H02J 2207/40 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360772 | Sikina et al. |
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| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Thomas V. Sikina (Acton, Massachusetts); John P. Haven (Lowell, Massachusetts); James E. Benedict (Lowell, Massachusetts); William J. Clark (Waltham, Massachusetts); Channing P. Favreau (Barre, Massachusetts); Erika Klek (Wilmington, Massachusetts); Mikhail Pevzner (Woburn, Massachusetts); Donald G. Hersey (Beverly, Massachusetts); Gregory G. Beninati (Salem, New Hampshire); Thomas J. Tellinghuisen (Pelham, New Hampshire) |
| ABSTRACT | Methods and apparatus for providing a cavity defined by conductive walls, a printed circuit board (PCB) within the cavity, and shorting posts extending into the cavity to suppress higher order modes generated by operation of the PCB. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/874794 |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/20 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0216 (20130101) Original (OR) Class H05K 1/0243 (20130101) H05K 7/1427 (20130101) H05K 2201/10613 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360782 | Thrasher et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carl J. Thrasher (Huber Heights, Ohio); Christopher E. Tabor (Kettering, Ohio); Zachary J. Farrell (Xenia, Ohio); Nicholas J. Morris (Dayton, Ohio) |
| ABSTRACT | The present invention relates to substrates comprising a network comprising core shell liquid metal encapsulates comprising multi-functional ligands and processes of making and using such substrates. The core shell liquid metal particles are linked via ligands to form such network. Such networks volumetric conductivity increases under strain which maintains a substrate's resistance under strain. The constant resistance results in consistent thermal heating via resistive heating. Thus allowing a substrate that comprises such network to serve as an effective heat provider. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/386807 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 3/10 (20130101) H05K 3/22 (20130101) H05K 2201/0245 (20130101) H05K 2201/0314 (20130101) H05K 2203/0783 (20130101) H05K 2203/1105 (20130101) H05K 2203/1131 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20210352926 | Martini |
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| FUNDED BY |
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| APPLICANT(S) | Utah State University (Logan, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Silvana Martini (North Logan, Utah) |
| ABSTRACT | The disclosure generally provides for lipid compositions, foodstuffs, and methods for reducing lipid migration in a food product, the methods comprise sonicating a low saturated lipid with a high intensity ultrasound, and incorporating the sonicated low saturated lipid to a food composition. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385726 |
| CURRENT CPC | Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 7/001 (20130101) A23D 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353010 | Harnett et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cindy K. Harnett (Louisville, Kentucky); Jasmine Beharic (Louisville, Kentucky); Canisha Ternival (Louisville, Kentucky); Sushmita Challa (Louisville, Kentucky); Mohammad Shafquatul Islam (Louisville, Kentucky) |
| ABSTRACT | Radial-armed thin-film bilayers are designed and fabricated from a metal and an oxide to produce grippers that interact with the yarns or fibers of the fabric and form a mechanical tangle attachment to the fabric. MEMs devices attached to the grippers enable the MEMs devices to be adhered to a flexible and/or extensible fabric. Fabrics comprise conventional textile, smart textiles, functional fibers or other smart materials. The fabrics thus incorporate wearable sensors, medical devices, and other functional MEMs for commercial, biomedical, industrial and scientific applications. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/983405 |
| CURRENT CPC | Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 13/0005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353147 | Melodia et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts); Laura Galluccio (Trecastagni, Italy); Sergio Palazzo (San Giovanni la Punta, Italy) |
| ABSTRACT | Methods and devices for transmitting and receiving data through biological tissue using ultrasonic pulses are described. Methods of the present invention may set an initial time-hopping frame length and an initial spreading code length for data transmission. A request-to-transmit may be sent from a transmitter over a control channel at the initial frame and code length. The receiver may respond to the transmitter with a clear-to-transmit packet having feedback information. The feedback information can be used to improve a forward time-hopping frame length and a forward spreading code length. Embodiments of the invention may involve a body area network or body surface network comprising a plurality of implanted sensor nodes operating according to the disclosed invention. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/157251 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0015 (20130101) A61B 5/0024 (20130101) A61B 5/026 (20130101) A61B 5/0028 (20130101) Original (OR) Class A61B 5/0031 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 23/02 (20130101) Transmission H04B 1/71635 (20130101) Selecting H04Q 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353549 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William L. Murphy (Waunakee, Wisconsin); Andrew Salim Khalil (Madison, Wisconsin); Xiaohua Yu (Mansfield Center, Connecticut) |
| ABSTRACT | Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral Layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379351 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/501 (20130101) Original (OR) Class A61K 38/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353585 | LAMMERDING et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jan LAMMERDING (Ithaca, New York); Tyler J. KIRBY (Brooktondale, New York); Gregory R. FEDORCHAK (Ithaca, New York); Ashley J. EARLE (Dryden, New York) |
| ABSTRACT | The present application relates to methods of treating a laminopathy affecting skeletal or cardiac muscle in a subject. The methods involve selecting a subject who has a laminopathy affecting skeletal or cardiac muscle. In some embodiments, the methods involve administering, to the selected subject, an inhibitor of a protein associated with a DNA damage response (DDR) pathway to treat the laminopathy affecting skeletal or cardiac muscle in the subject. In other embodiments, the methods involve administering, to the selected subject, a microtubule stabilizing agent and a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor to treat the laminopathy affecting skeletal or cardiac muscle in the subject. Also disclosed are pharmaceutical compositions comprising an inhibitor of a protein associated with a DNA damage response (DDR) pathway, a microtubule stabilizing agent, and/or a Linker of Nucleoskeleton and Cytoskeleton (LINC) complex disruptor. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 17/274131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353743 | Bencherif et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University Center for Research Innovation, Northeastern Univ. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sidi A. Bencherif (Boston, Massachusetts); Thibault Colombani (Boston, Massachusetts) |
| ABSTRACT | Disclosed are compositions and methods for preventing an infection, such as COVID-19 infection, comprising administering to the subject an oxygen-generating cryogel, wherein the oxygen-generating cryogel comprises an antigen, a chemoattractant for immune cells, an adjuvant, such as toll-like receptor 9 (TLR9) ligand, and an oxygen-producing compound. Described herein are methods of modulating the immune system in a subject, comprising administering an effective amount of the vaccine described herein to the subject, thereby modulating the immune system in the subject. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322054 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/55561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210353835 | GUAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zeyi GUAN (Los Angeles, California); Jingke LIU (Los Angeles, California); Jasmine LI (Los Angeles, California); Xiaochun LI (Los Angeles, California); Injoo HWANG (Los Angeles, California) |
| ABSTRACT | A biomedical device includes a zinc-based material including a matrix including zinc, and nanostructures dispersed in the matrix. Embodiments of this disclosure are directed to zinc (Zn)-based materials including dispersed nanostructures for biomedical applications and devices, such as bioresorbable vascular stents, bioresorbable ureteral stents, endoluminal springs for distraction enterogenesis, biodegradable bone implants with tunable modulus, guided bone generation membranes, bioresorbable dental membranes, and other biomedical implants, as well as other functional applications, such as biodegradable electronics and sensors. |
| FILED | Thursday, August 01, 2019 |
| APPL NO | 17/265163 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/122 (20130101) A61L 31/124 (20130101) Original (OR) Class A61L 2400/12 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 18/06 (20130101) Alloys C22C 1/1036 (20130101) C22C 32/0052 (20130101) C22C 2001/1047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354109 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354121 | Di Carlo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Chueh-Yu Wu (Los Angeles, California); Ghulam Destgeer (Los Angeles, California); Mengxing Ouyang (Culver City, California) |
| ABSTRACT | Sub-millimeter scale three-dimensional (3D) structures are disclosed with customizable chemical properties and/or functionality. The 3D structures are referred to as drop-carrier particles. The drop-carrier particles allow the selective association of one solution (i.e., a dispersed phased) with an interior portion of each of the drop-carrier particles, while a second non-miscible solution (i.e., a continuous phase) associates with an exterior portion of each of the drop-carrier particles due to the specific chemical and/or physical properties of the interior and exterior regions of the drop-carrier particles. The combined drop-carrier particle with the dispersed phase contained therein is referred to as a particle-drop. The selective association results in compartmentalization of the dispersed phase solution into sub-microliter-sized volumes contained in the drop-carrier particles. The compartmentalized volumes can be used for single-molecule assays as well as single-cell, and other single-entity assays. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387990 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0262 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502784 (20130101) B01L 2300/021 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354357 | Panchal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leonine Technologies Inc. (Lowell, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rahul R. Panchal (Brookline, New Hampshire) |
| ABSTRACT | A shrinkage detection device for a polymer injection molding apparatus detects a shrinkage experienced by an injection molded element for assessing a quality of the molded element. Shrinkage, along with temperature and pressure of the melt within the mold during cooling, indicates a sufficiency of the resulting molded element for intended purposes. Sufficiency includes parameters such as flexibility, shear strength and longevity, and is accurately performed can replace conventional sample testing of molded articles that are expensive and time consuming. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318951 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/77 (20130101) B29C 45/78 (20130101) B29C 45/80 (20130101) B29C 45/768 (20130101) Original (OR) Class B29C 2945/7604 (20130101) B29C 2945/76006 (20130101) B29C 2945/76096 (20130101) B29C 2945/76103 (20130101) B29C 2945/76458 (20130101) B29C 2945/76481 (20130101) B29C 2945/76488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355064 | CRONIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Steve P. CRONIN (Louisville, Kentucky); Craig A. GRAPPERHAUS (Jeffersonville, Indiana); Robert M. BUCHANAN (Louisville, Kentucky); Jacob M. STRAIN (Louisville, Kentucky); Joshua M. SPURGEON (Louisville, Kentucky) |
| ABSTRACT | Some embodiments of the invention include methods of using a compound (e.g., Formula (I)) for the reduction of carbon dioxide to formate by contacting the carbon dioxide with a composition comprising a compound. In certain embodiments, the source of the carbon dioxide is air or is flue gas. Additional embodiments of the invention are also discussed herein. |
| FILED | Saturday, July 31, 2021 |
| APPL NO | 17/444185 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 2531/26 (20130101) B01J 2531/0238 (20130101) Acyclic or Carbocyclic Compounds C07C 51/41 (20130101) Original (OR) Class C07C 53/06 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355099 | AHMED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. AHMED (Pasadena, California); Robert H. GRUBBS (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336756 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355246 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan Luo (Ithaca, New York); Dong Wang (Ithaca, New York) |
| ABSTRACT | Crosslinked nucleotide polymers. A crosslinked nucleotide polymer may be formed by reaction of a biomass comprising DNA and/or RNA with one or more crosslinker(s). A crosslinked nucleotide polymers may be formed by a crosslinking reaction including an aza-Michael addition reaction. Crosslinked nucleotide polymers may be present in various forms and compositions and form various articles of manufacture. Crosslinked nucleotide polymers may be used in therapeutic methods, coating methods, and cell-free protein production methods. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318845 |
| CURRENT CPC | Separation B01D 11/0288 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0003 (20130101) Original (OR) Class C08B 37/003 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/09 (20130101) C08J 2367/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355499 | Simon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Anne Elizabeth Simon (Bowie, Maryland) |
| ABSTRACT | The present disclosure relates to a single stranded RNA vector suitable for introducing a therapeutic agent, such as a peptide, a protein or a small RNA, into a host plant. The vector does not encode for any movement protein or coat protein, but is capable of capable of systemic and phloem-limited movement and replication within the host plant. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317596 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355512 | REDDY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts); Western Washington University (Bellingham, Washington); Marine Biological Laboratory (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts); Western Washington University (Bellingham, Washington); Marine Biological Laboratory (Woods Hole, Massachusetts) |
| INVENTOR(S) | CHRISTOPHER M. REDDY (WOODS HOLE, Massachusetts); GREGORY W. O'NEIL (BELLINGHAM, Wisconsin); SCOTT R. LINDELL (WOODS HOLE, Massachusetts) |
| ABSTRACT | A method comprising a series of selective extraction techniques for the parallel production of biodiesel and isolation of several valuable co-products including an alkenone hydrocarbon mixture of the kerosene/jet fuel range (primarily C10-, C12-, and C17-hydrocarbons) and fucoxanthin, a high-valued carotenoid, from the marine alkenone-producing microalgae Isochrysis. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/388298 |
| CURRENT CPC | Heterocyclic Compounds C07D 303/32 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/19 (20130101) C10L 1/185 (20130101) C10L 1/1802 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/003 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/26 (20130101) C12P 7/649 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355588 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaowei Chen (Santa Cruz, California); Bingzhang Lu (Santa Cruz, California); Lin Guo (Santa Cruz, California); Yi Peng (Santa Cruz, California); Jia-En Lu (Santa Cruz, California) |
| ABSTRACT | A catalyst nanocomposite and methods of making the same. The catalyst nanocomposite includes a substrate; and a coating disposed on the substrate, the coating having a ruthenium and nitrogen co-doped carbon matrix. The coating may be melamine and formaldehyde and produced via pyrolizing the melamine and formaldehyde on a nanowire made of metals such as tellurium. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/282156 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/052 (20210101) C25B 11/061 (20210101) C25B 11/091 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356366 | McGrath et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | James Lionel McGrath (Rochester, New York); Kilean Scott Lucas (Bozeman, Montana); Henry Hung Li Chung (Rochester, New York) |
| ABSTRACT | A device and method for isolating extracellular vesicles from biofluids is disclosed. A nanoporous silicon nitride membrane is provided with a tangential flow of biofluid. A pressure gradient through the nanoporous silicon nitride membrane facilitates capture of extracellular vesicles from the tangential flow vector of biofluid. Reversal of the pressure gradient results in the release of the extracellular vesicles for subsequent collection. |
| FILED | Sunday, January 08, 2017 |
| APPL NO | 16/476329 |
| CURRENT CPC | Separation B01D 69/02 (20130101) B01D 71/02 (20130101) B01D 71/52 (20130101) B01D 2325/027 (20130101) B01D 2325/42 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4005 (20130101) Original (OR) Class G01N 2001/4016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356381 | Diebold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Becton, Dickinson and Company (Franklin Lakes, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric D. Diebold (Los Angeles, California); Keegan Owsley (Los Angeles, California); Jonathan Lin (Los Angeles, California) |
| ABSTRACT | In one aspect, a method of sorting cells in a flow cytometry system is disclosed, which includes illuminating a cell with radiation having at least two optical frequencies shifted from one another by a radiofrequency to elicit fluorescent radiation from the cell, detecting the fluorescent radiation to generate temporal fluorescence data, and processing the temporal fluorescence data to arrive at a sorting decision regarding the cell without generating an image (i.e., a pixel-by-pixel image) of the cell based on the fluorescence data.. In other words, while the fluorescence data can contain image data that would allow generating a pixel-by-pixel fluorescence intensity map, the method arrives at the sorting decision without generating such a map. In some cases, the sorting decision can be made with a latency less than about 100 microseconds, In some embodiments, the above method of sorting cells can have a sub-cellular resolution, e.g., the sorting decision can be based on characteristics of a component of the cell. In some embodiments in which more than two frequency-shifted optical frequencies are employed, a single radiofrequency shift is employed to separate the optical frequencies while in other such embodiments a plurality of different radiofrequency shifts are employed. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386192 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1429 (20130101) G01N 15/1434 (20130101) Original (OR) Class G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 2015/1006 (20130101) G01N 2015/1447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356398 | Yuan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas); Tingfeng Yao (Arlington, Texas) |
| ABSTRACT | A method of imaging described herein comprises (a) disposing ultrasound-switchable fluorophores within an environment; (b) exposing the environment to ultrasound to create a first activation region within the environment; (c) disposing the fluorophores within the first activation region to switch the fluorophores from an off state to an on state; (d) irradiating the environment to excite the fluorophores within the first activation region; (e) detecting photoluminescence from the excited fluorophores at a first optical spot on an exterior surface of the environment; (f) subsequently creating a second activation region within the environment; (g) switching fluorophores within the second activation region to an on state; (h) exciting the fluorophores in the on state within the second activation region; and (i) detecting photoluminescence from the excited fluorophores within the second activation region at a second optical spot on the exterior surface, wherein the first and second optical spots are optically resolvable. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 17/286126 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2021/6439 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356417 | Babakhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Yuxiang Sun (Los Angeles, California) |
| ABSTRACT | Wirelessly powered dielectric sensor in accordance with embodiments of the invention are disclosed. In many embodiments, a wirelessly powered dielectric sensor includes an RF-power receiving antenna that receives electromagnetic power, a power management unit (PMU) including a capacitor to rectify and store the electromagnetic power, and a dielectric constant sensing sensor, where the PMU monitors harvested energy and operates the dielectric sensing sensor; and where the dielectric sensing sensor senses a dielectric constant of a material that is in close proximity. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 17/287432 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 2560/0219 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/221 (20130101) G01N 27/228 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/20 (20160201) H02J 50/80 (20160201) H02J 2310/23 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357621 | Khandelwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ankush Khandelwal (Minneapolis, Minnesota); Anuj Karpatne (Minneapolis, Minnesota); Vipin Kumar (Minneapolis, Minnesota) |
| ABSTRACT | A method includes receiving a satellite image of an area and classifying each pixel in the satellite image as representing water, land or unknown using a model. For each of a plurality of possible water levels, a cost associated with the water level is determined, wherein determining the cost associated with a water level includes determining a number of pixels for which the model classification must change to be consistent with the water level and determining a difference between the water level and a water level determined for the area at a previous time point. The lowest cost water level is selected and used to reclassify at least one pixel. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/362054 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) Original (OR) Class G06K 9/00651 (20130101) G06K 9/6202 (20130101) G06K 9/6255 (20130101) G06K 9/6267 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/55 (20170101) G06T 2207/10032 (20130101) G06T 2207/30188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357630 | Shaevitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Joshua W. Shaevitz (Princeton, New Jersey); Mala Murthy (Princeton, New Jersey); Talmo D. Pereira (Princeton, New Jersey); Diego E. Aldarondo (Somerville, Massachusetts) |
| ABSTRACT | Disclosed are a system and method for quantifying changes in animal posture from video recordings of multiple interacting animals. Also disclosed are a system and method for training a posture identification algorithm efficiently with minimal human effort and evaluating the posture of millions of animal images. The disclosed process employs video recordings of behaving animals to produce a full set of geometrical coordinates for each body part over time. Inter alia, the disclosed system should be useful for organizations interested in doing large small-molecule screens to find drugs that affect the behavior of animals, and for those investigating new behavioral diagnostics for human patients. The disclosed system allows one to record video of animals and then automatically calculate the position of each body part over time. The output of this calculation can be used for simple analysis of the amount of movement for specific body parts, or part of a more complex scheme for measuring behaviors. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282818 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04845 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) Original (OR) Class G06K 9/00744 (20130101) G06K 9/6223 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/251 (20170101) G06T 2207/10016 (20130101) G06T 2207/20101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357648 | METAXAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dimitris METAXAS (New Brunswick, New Jersey); Zachary A. DANIELS (New Brunswick, New Jersey) |
| ABSTRACT | An image processing neural network system includes a base net of at least one convolutional layer and at least one pooling layer; and a scenario block layer. The scenario block layer performs scene classification and generates a dictionary of scenarios and a vector of scenario encoding coefficients to output a probabilistic scene class assignment and the vector of scenario encoding coefficients. The vector of scenario encoding coefficients corresponds to reasoning for the scene classification. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/790641 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00718 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357703 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jie Fan (Tempe, Arizona); Sunil Rao (Tempe, Arizona); Gowtham Muniraju (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona); Andreas Spanias (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Jie Fan (Tempe, Arizona); Sunil Rao (Tempe, Arizona); Gowtham Muniraju (Tempe, Arizona); Cihan Tepedelenlioglu (Tempe, Arizona); Andreas Spanias (Tempe, Arizona) |
| ABSTRACT | Various embodiments of a system and associated method for detecting and classifying faults in a photovoltaic array using graph-based signal processing. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318046 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) G06K 9/6259 (20130101) G06K 9/6268 (20130101) Original (OR) Class G06K 9/6296 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357729 | Leino et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Klas Leino (Pittsburgh, Pennsylvania); Shayak Sen (Pittsburgh, Pennsylvania); Anupam Datta (Palo Alto, California); Matthew Fredrikson (Pittsburgh, Pennsylvania) |
| ABSTRACT | A computing machine accesses a set of intermediate artificial neurons in a deep neural network. The deep neural network is fully or partially trained. The computing machine computes, for each artificial neuron in the set of intermediate artificial neurons, an influence score based on an average gradient of an output quantity of interest with respect to the artificial neuron across a plurality of inputs weighted by a probability of each input. The computing machine provides an output associated with the computed influence scores. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583392 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0472 (20130101) Original (OR) Class G06N 3/0481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357741 | Jha |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Niraj K. Jha (Princeton, New Jersey) |
| ABSTRACT | In a system and method for processing detected signals at a detector using a processor, a set of data is converted into a compressed set of data using a compressive sensing component controlled via a processor, the compressed set of data is transformed into a vector and the vector is filtered using a machine learning component controlled via the processor, the filtered vector is encrypted using an encryption component controlled via the processor, and the filtered vector is integrity protected using an integrity protection component controlled via the processor. |
| FILED | Wednesday, January 24, 2018 |
| APPL NO | 16/479714 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 20/10 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3239 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358636 | Ho et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chih-Ming Ho (Los Angeles, California); Xianting Ding (Los Angeles, California); Ieong Wong (Los Angeles, California) |
| ABSTRACT | Multiple tests of a complex system are conducted by applying varying combinations of input parameters from a pool of input parameters. Results of the tests are fitted into a model of the complex system by using multi-dimensional fitting. Using the model of the complex system, identification is made of at least one optimized combination of input parameters to yield a desired response of the complex system. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/390505 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) G06F 30/20 (20200101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/70 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358642 | Meyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Laurent Audoly (, None); Vanderbilt University (Nashville, Tennessee); Parthenon Therapeutics, Inc. (Brookline, Massachusetts); DUET Biosystems, Inc. (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian T. Meyer (Nashville, Tennessee); Vito Quaranta (Nashville, Tennessee); Leonard A. Harris (Nashville, Tennessee); Buddhi Bishal Paudel (Nashville, Tennessee); David J. Wooten (Nashville, Tennessee); Laurent Audoly (Brookline, Massachusetts) |
| ABSTRACT | The invention provides methods for evaluating the therapeutic benefit of a combination therapy useful for treating a medical disorder, such as cancer. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180280 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 70/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358714 | GANDHIRAMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Space Foundry Inc. (Los Gatos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramprasad GANDHIRAMAN (San Jose, California); Fergal John O'MOORE (Los Gatos, California); Lief Niklas Dennis NORDLUND (Menlo Park, California); Arlene Lynette LOPEZ (Long Beach, California) |
| ABSTRACT | Described herein are apparatus and methods of printing in the presence of plasma. The apparatus includes a modular print head comprising an inlet module, a plasma module with movable electrode configurations, and a nozzle module. The modular design of the print head allows for printing on and treatment of surfaces in many different applications. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176905 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/10 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359099 | Shen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pin-Chun Shen (Changhua, Taiwan); Jing Kong (Winchester, Massachusetts) |
| ABSTRACT | Devices, such as transistors, that use bismuth to create ohmic contacts are provided, as are methods of manufacturing the same. The transistors, such as field-effect transistors, can include one or more two-dimensional materials, and electrical contact areas can be created on the two-dimensional material(s) using bismuth. The bismuth can help to provide energy-barrier free, ohmic contacts, and the resulting devices can have performance levels that rival or exceed state-of-the-art devices that utilize three-dimensional materials, like silicon. The two-dimensional materials can include transition metal dichalcogenides, such as molybdenum disulfide. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/320183 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/45 (20130101) H01L 29/4983 (20130101) Original (OR) Class H01L 29/66628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359151 | FERRY et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David FERRY (Scottsdale, Arizona); Vincent WHITESIDE (Buffalo, New York); Ian R. SELLERS (Norman, Oklahoma) |
| ABSTRACT | A photovoltaic device configured to substantially avoid radiative recombination of photo-generated carriers, reduce loss of energy of the photo-generated carriers through the phonon emission, extract photo-generated carriers substantially exclusively from the multi-frequency satellite valley(s) of the bandstructure of the used semiconductor material as opposed to the single predetermined extremum of the bandstructure. Methodologies of fabrication and operation of such a device. |
| FILED | Monday, October 14, 2019 |
| APPL NO | 17/285360 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0735 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359408 | Theofanopoulos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Panagiotis Theofanopoulos (Tempe, Arizona); Georgios Trichopoulos (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Panagiotis Theofanopoulos (Tempe, Arizona); Georgios Trichopoulos (Tempe, Arizona) |
| ABSTRACT | A single-switch-per-bit topology for reconfigurable reflective surfaces (RRSs) is provided. Novel multi-bit unit-cell configurations are presented for radio-frequency (RF) RRSs with improved radiation efficiency and compact designs. Embodiments described herein realize a multi-bit RRS using an antenna array with multiple integrated switches at the ports of every antenna element (e.g., one at each port, providing one control bit per switch). By manipulating the states of the switches, the impinging waves on the surface are modulated, leading to beamforming in the desired direction. Some embodiments utilize a single switch-per-bit topology integrating single-pole-single-throw (SPST) switches (e.g., PIN diodes) into the unit-cell design, achieving up to 4 bits of phase quantization with only 4 switches. The exhibited radiation efficiency of the multi-bit RRS is significantly improved compared to lower bit configurations. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/323560 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/50 (20130101) H01Q 3/36 (20130101) H01Q 3/247 (20130101) Original (OR) Class Transmission H04B 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359409 | Gómez-Diaz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Juan Sebastián Gómez-Diaz (Davis, California); Diego Correas Serrano (Phoenix, Arizona); Alejandro Álvarez-Melcón (Cartagena, Spain); Jiawei Zang (Beijing, China PRC) |
| ABSTRACT | The disclosed embodiments relate to the design of a system that implements a reflectarray antenna. The system includes a time-modulated metasurface, which is configured to act as a planar reflector for an electromagnetic wave that is radiated by a feeder into free space at an operation frequency f0. The time-modulated metasurface includes time-modulated unit-cells that provide a nonlinear conversion between f0 and another desired frequency fd. The system also includes a phase-delay mechanism, which adjusts a phase delay by acting on a phase applied to a modulation frequency fm that modulates each unit-cell. The nonlinear conversion and the phase-delay mechanism operate collectively to facilitate angle-independent nonreciprocity by imposing different phase gradients during up-conversion and down-conversion processes, and by preventing generation of certain propagative harmonics due to total internal reflection. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/715520 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/288 (20130101) H01Q 3/46 (20130101) Original (OR) Class H01Q 15/148 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360515 | CHOWDHURY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kaushik CHOWDHURY (Needham, Massachusetts); Kunal SANKHE (Boston, Massachusetts); Dheryta JAISINGHANI (Cambridge, Massachusetts) |
| ABSTRACT | Systems, devices, and methods for access point discovery in a wireless network are provided. An access point device embeds into a preamble of a transmission packet discovery information including modifications determined by passing in-phase quadrature (IQ) symbols through a finite impulse response (FIR) filter to introduce a phase shift in selected ones of the IQ symbols. The phase shifts are encoded into bits in selected ones of a plurality of subcarriers, bounded by a maximum phase shift and a maximum number of the subcarriers to limit the packet error rate. A convolutional neural network can learn channel state and other information to determine the maximum phase shift and number of subcarriers. A client device can select from among a plurality of modified transmission packets to send a discovery request. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/319141 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/006 (20130101) H04L 5/0094 (20130101) H04L 25/0254 (20130101) Wireless Communication Networks H04W 48/16 (20130101) Original (OR) Class H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360833 | Alissa et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Husam Alissa (Redmond, Washington); Kourosh Nemati (Rockville, Maryland); Baghat Sammakia (Binghamton, New York); Kanad Ghose (Vestal, New York) |
| ABSTRACT | A method of controlling a data center having a cold air cooling system, and at least one containment structure, comprising: determining a minimum performance constraint; determining optimum states of the cold air cooling system, a controlled leakage of air across the containment structure between a hot region and a cold air region, and information technology equipment for performing tasks to meet the minimum performance constraint, to minimize operating cost; and generating control signals to the cold air cooling system, a controlled leakage device, and the information technology equipment in accordance with the determined optimum states. |
| FILED | Saturday, July 24, 2021 |
| APPL NO | 17/384733 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20745 (20130101) H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20210352926 | Martini |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Utah State University (Logan, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Silvana Martini (North Logan, Utah) |
| ABSTRACT | The disclosure generally provides for lipid compositions, foodstuffs, and methods for reducing lipid migration in a food product, the methods comprise sonicating a low saturated lipid with a high intensity ultrasound, and incorporating the sonicated low saturated lipid to a food composition. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385726 |
| CURRENT CPC | Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 7/001 (20130101) A23D 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354083 | Pavlish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Midwest Energy Emissions Corp (Corsicana, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John H. Pavlish (East Grand Forks, Minnesota); Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota) |
| ABSTRACT | Various embodiments disclosed relate to sorbents for the oxidation and removal of mercury. The present invention includes removing mercury from a mercury-containing gas using a halide-promoted and optionally ammonium-protected sorbent that can include carbon sorbent, non-carbon sorbent, or a combination thereof. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209720 |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 53/83 (20130101) B01D 2251/108 (20130101) B01D 2251/206 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 2220/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354084 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bu Wang (Madison, Wisconsin); Raghavendra Ragipani (Madison, Wisconsin) |
| ABSTRACT | A method of sequestering gaseous carbon dioxide in which an oxide is carbonated by contacting it with a first aqueous carbonate solution to convert a portion of the oxide into a carbonate, which precipitates from solution. By converting the oxide to a solid carbonate, the CO2 from the first carbonate solution is sequestered into the precipitate. At the same time, an aqueous hydroxide solution is formed. The aqueous hydroxide solution is contacted with gaseous carbon dioxide which sequesters the gaseous CO2 into a second aqueous carbonate solution. The second solution so generated is then recycled back into the process and used to convert the oxide into the precipitated carbonate. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318424 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/78 (20130101) Original (OR) Class B01D 53/96 (20130101) B01D 53/1425 (20130101) B01D 53/1475 (20130101) B01D 2251/304 (20130101) B01D 2251/306 (20130101) B01D 2257/504 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354094 | FRAYNE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Via Separations, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Via Separations, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Stephen FRAYNE (Watertown, Massachusetts); Michelle MACLEOD (Somerville, Massachusetts); Brandon Ian MACDONALD (Melrose, Massachusetts); Lymaris ORTIZ RIVERA (Cambridge, Massachusetts); Brent KELLER (Somerville, Massachusetts) |
| ABSTRACT | Embodiments described herein relate generally to durable graphene oxide membranes for fluid filtration. For example, the graphene oxide membranes can be durable under high temperatures non-neutral pH, and/or high pressures. One aspect of the present disclosure relates to a filtration apparatus comprising: a support substrate, and a graphene oxide membrane disposed on the support substrate. The graphene oxide membrane has a first lactose rejection rate of at least 50% with a first 1 wt % lactose solution at room temperature. The graphene oxide membrane has a second lactose rejection rate of at least 50% with a second 1 wt % lactose solution at room temperature after the graphene oxide membrane is contacted with a solution that is at least 80° C. for a period of time. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 17/380566 |
| CURRENT CPC | Separation B01D 67/0069 (20130101) B01D 67/0093 (20130101) B01D 69/10 (20130101) B01D 71/021 (20130101) Original (OR) Class B01D 2323/36 (20130101) B01D 2325/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354799 | Mundon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oscilla Power, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Mundon (Seattle, Washington); Balakrishnan G Nair (Sandy, Utah) |
| ABSTRACT | A system includes an unmanned underwater vehicle (UUV), a reaction structure configured to deploy from a body of the UUV, and one or more tendons connecting the reaction structure to the body of the UUV, wherein the reaction structure deploys at a depth below the body of the UUV. The system further includes one or more power take-out (PTO) units coupled to or between the reaction structure and the UUV. The system further includes a control unit coupled to the one or more PTO units to convert energy from waves on a surface of a body of water for use in other systems within the UUV. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/319036 |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Original (OR) Class B63G 2008/004 (20130101) Machines or Engines for Liquids F03B 13/20 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2240/97 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355006 | McGrail et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bernard P. McGrail (Pasco, Washington); Jeromy W. J. Jenks (Hines, Oregon); Satish K. Nune (Richland, Washington); Herbert T. Schaef (West Richland, Washington) |
| ABSTRACT | Systems for removing one or more contaminants from water are provided that can include a hydrate formation chamber assembly; a contaminated water diffusion assembly within the hydrate formation chamber assembly; a space between a wall of the hydrate formation chamber assembly and the diffusion assembly; and a guest compound conduit configured to provide a guest compound within the space and form a hydrate comprising water and the guest compound. Methods for removing one or more contaminants from water are provided that can include providing a contaminated water mixture and one or more guest compounds; forming a hydrate complex comprising water and the one or more guest compounds; and separating the water from the guest compounds to provide water with less contaminant. Mixtures are also provided that can include a liquid component comprising water and at least one contaminant, and a solid component comprising a hydrate complex. One embodiment of the system provides methods for production of excess electric power as a byproduct of the desalination process. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322865 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/04 (20130101) C02F 1/683 (20130101) Original (OR) Class C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355261 | Pearson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Ryan Michael Pearson (Berkeley, California); Matthew David Ryan (Berkeley, California); Garret Miyake (Fort Collins, Colorado) |
| ABSTRACT | Polymer composite photonic crystal materials are disclosed as coatings with topcoats having high reflection (>30%) in a specific range of the electromagnetic spectrum, such as ultraviolet (<400 nm), visible (Vis, 400 nm-700 nm), or near-infrared radiation range (NIR, 700-2000 nm), and optionally a relatively low reflection (<20% reflection) in a second, different range of the electromagnetic spectrum. Surprisingly, it was found that through a multi-layer coating approach, the optical properties of polymer composite photonic crystal films can be selectively modified from a variety of different coating methods, including spray deposition. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/390259 |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00865 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 299/0485 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355565 | Rios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orlando Rios (Oak Ridge, Tennessee); Hunter B. Henderson (Knoxville, Tennessee); Michael S. Kesler (Oak Ridge, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ryan Ott (Ames, Iowa); Corby Anderson (Golden, Colorado); Hao Cui (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Orlando Rios (Oak Ridge, Tennessee); Hunter B. Henderson (Knoxville, Tennessee); Michael S. Kesler (Oak Ridge, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ryan Ott (Ames, Iowa); Corby Anderson (Golden, Colorado); Hao Cui (Golden, Colorado) |
| ABSTRACT | The disclosure concerns methods for making a composition comprising a light metal and an intermetallic comprising the light metal and a light rare earth element. The composition also may include a plurality of nanoparticles comprising an oxide of the light metal. The method includes directly reducing a light rare earth element precursor compound in a melt of the light metal, thereby forming the light rare earth element and nanoparticles of the light metal oxide. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781635 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Alloys C22C 1/026 (20130101) C22C 1/0416 (20130101) C22C 1/0491 (20130101) C22C 21/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355581 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongping Zhao (Columbus, Ohio); Zhaoying Chen (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are laser-assisted metal-organic chemical vapor deposition devices and methods of use thereof. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876798 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/483 (20130101) Original (OR) Class C23C 16/4584 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/12 (20130101) C30B 25/14 (20130101) C30B 25/105 (20130101) C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/68764 (20130101) H01L 21/68771 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355839 | Kesseli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Kesseli (Geenland, New Hampshire); Thomas Wolf (Winchester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Kesseli (Geenland, New Hampshire); Thomas Wolf (Winchester, Massachusetts) |
| ABSTRACT | Electrical energy storage is critical to increased adoption of renewable energy resources such as solar and wind power. Apparatuses, systems and methods are disclosed for storing electrical energy as thermal energy and retrieving electrical energy from the stored thermal energy on a large utility scale. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169234 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 13/006 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355906 | Mundon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oscilla Power, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Mundon (Seattle, Washington) |
| ABSTRACT | A system includes a float including a drivetrain, a reaction structure coupled to the drivetrain by a tendon, and an extension spring having a first end coupled to a fixed point on the tendon and a second end configured to be disposed at a fixed location relative to the drivetrain. The extension spring is configured to experience an elastic force in response to tension on the first end of the extension spring away from the drivetrain. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/319040 |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356193 | Dhuley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ram Dhuley (Aurora, Illinois) |
| ABSTRACT | Methods and systems for bolted joint conduction cooling of accelerator cavities comprises a conduction cooling system. The conduction cooling system comprises mounting at least one cooling ring to a cavity and a conduction link joined to the cooling ring with at least one connection assembly. The materials in the at least one connection assembly can be selected to experience greater thermal contraction than the cooling ring and the conduction link when cooled. A fast conduction cooling system can comprise a cryocooler in thermal communication with a conduction cooling apparatus affixed to a cavity via a conduction path and a thermal switch in the conduction path between the cryocooler and the conduction cooling apparatus wherein a thermal conductance of the thermal switch decreases as a function of temperature. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/306481 |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 19/006 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/02 (20130101) H05H 7/20 (20130101) H05H 2007/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356325 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samantha Taylor (West Chester, Ohio); Eric Christopher Forrest (Albuquerque, New Mexico) |
| ABSTRACT | Embodiments of the present disclosure provide an improved method and apparatus for thermal monitoring for a metal additive manufacturing system. An emissivity value of a top surface of an object to be manufactured is determined based, at least in part, on an arithmetic product of a predetermined roughness value and a predetermined slope-related value. The predetermined roughness value and slope-related values are predetermined based, at least in part, on measurements of a previously manufactured object. The system sinters a metal to form the top surface of the object to be manufactured. An infrared sensor detects radiation from at least a portion of the top surface of the object to be manufactured. A temperature is generated based, at least in part, on the detected infrared radiation and the emissivity value and the generated temperature is applied to a temperature utilization component of the system. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876725 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 2003/1057 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/00 (20130101) Original (OR) Class G01J 2005/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356435 | Pantea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cristian Pantea (Los Alamos, New Mexico); John James Greenhall (Santa Fe, New Mexico); Alan Lyman Graham (Los Alamos, New Mexico); Dipen N. Sinha (Bay Shore, New York) |
| ABSTRACT | Techniques are provided for detecting wafer defects. Example techniques include exciting a wafer using an acoustic signal to cause the wafer to exhibit vibrations, measuring one or more of linear frequency response metrics or nonlinear frequency responses metrics associated with the vibrations, and identifying any defects in the wafer based at least in part on one or more of the linear frequency response metrics or nonlinear frequency responses metrics. In embodiments, the wafer includes bismuth telluride (Bi2Te3). |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/321332 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/12 (20130101) Original (OR) Class G01N 29/27 (20130101) G01N 29/46 (20130101) G01N 29/225 (20130101) G01N 29/2418 (20130101) G01N 29/2437 (20130101) G01N 2291/011 (20130101) G01N 2291/023 (20130101) G01N 2291/101 (20130101) G01N 2291/0289 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356626 | FEIGENBAUM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Eyal FEIGENBAUM (Livermore, California); Nathan James RAY (Tracy, California); Jae Hyuck YOO (Dublin, California) |
| ABSTRACT | A method and system is disclosed for creating an optical component having a spatially controlled refractive index and uniform anti-reflective layer. The method may involve alternately depositing and dewetting two or more thin metal material layers on the substrate to form a mask having a spatially varying nano-particle distribution, and with an increased thickness beyond what could be achieved using a single, thick layer of the same material. The substrate may then be etched, using the mask, to imprint a spatially patterned nanostructure pattern on a surface the substrate in accordance with the mask. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875337 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/11 (20130101) G02B 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356738 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Jonathan Fan (Los Altos, California); Jiaqi Jiang (Stanford, California); Mingkun Chen (Palo Alto, California) |
| ABSTRACT | A method for optimization of photonic devices is disclosed. The method includes receiving a set of unconstrained latent variables; mapping the set of unconstrained latent variables to a constrained space to generate a constrained device; calculating the permittivity across each element of the constrained device; determining a permittivity-constrained width gradient based at least partially on the permittivity across each element; and optimizing the set of unconstrained latent variables by at least partially using the permittivity-constrained width gradient. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317624 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/0228 (20130101) G01M 11/0242 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0012 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356916 | Wenzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Johnson Controls Technology Company (Auburn Hills, Michigan) |
| ASSIGNEE(S) | Johnson Controls Technology Company (Auburn Hills, Michigan) |
| INVENTOR(S) | Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin) |
| ABSTRACT | A system includes a processing circuit configured to provide an energy use setpoint based on energy data including an energy characteristic and subject to a constraint based on a variable condition of a building. The processing circuit is configured to estimate a value for the energy use setpoint that will result in the variable condition of the building satisfying the constraint and provide a control signal for equipment based on a difference between the energy use setpoint and a measured energy use. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/389093 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/30 (20180101) F24F 11/46 (20180101) F24F 11/62 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Electric Digital Data Processing G06F 1/3203 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0201 (20130101) G06Q 30/0202 (20130101) G06Q 30/0206 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/14 (20130101) H04L 12/2803 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/84 (20151101) Y02P 90/845 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357719 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behaft of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul B. Johnson (Phoenix, Arizona); Jose Antonio Bautista-Martinez (Mesa, Arizona); Cody A. Friesen (Fort McDowell, Arizona); Elise Switzer (Napa, California) |
| ABSTRACT | The disclosed technology relates generally to apparatus comprising conductive polymers and more particularly to tag and tag devices comprising a redox-active polymer film, and method of using and manufacturing the same. In one aspect, an apparatus includes a substrate and a conductive structure formed on the substrate which includes a layer of redox-active polymer film having mobile ions and electrons. The conductive structure further includes a first terminal and a second terminal configured to receive an electrical signal therebetween, where the layer of redox-active polymer is configured to conduct an electrical current generated by the mobile ions and the electrons in response to the electrical signal. The apparatus additionally includes a detection circuit operatively coupled to the conductive structure and configured to detect the electrical current flowing through the conductive structure. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/164241 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/122 (20130101) C08G 61/123 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0702 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) G06K 19/07743 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/608 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358646 | Wellons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew S. Wellons (AIKEN, South Carolina); Michael A. Devore, II (NORTH AUGUSTA, South Carolina); Wendy W. Kuhne (EVANS, Georgia) |
| ABSTRACT | Methods for forming particulates that are highly consistent with regard to shape, size, and content are described. Particulates are suitable for use as reference materials. Methods can incorporate actinides and/or lanthanides, e.g., uranium, and can be used for forming certified reference materials for use in the nuclear industry. Methods include formation of an aerosol from an oxalate salt solution, in-line diagnostics, and collection of particles of the aerosol either in a liquid impinger or on a solid surface. |
| FILED | Wednesday, May 13, 2020 |
| APPL NO | 15/930639 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/46 (20130101) Nuclear Reactors G21C 3/60 (20130101) Original (OR) Class G21C 3/623 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358660 | Majkic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Goran Majkic (Houston, Texas); Anis Ben Yahia (Houston, Texas); Wenbo Luo (Houston, Texas); Venkat Selvamanickam (Houston, Texas); Soumen Kar (Houston, Texas) |
| ABSTRACT | A round superconductor wire and method for fabricating same are disclosed. Embodiments are directed to a round superconductor wire including at least two superconductor tapes wound on a wire former. Each superconductor tape includes: bottom stabilizer and silver layers; substrate disposed above the bottom silver layer; buffer film stack disposed above the substrate; superconductor film disposed above the buffer film stack; top silver layer disposed above the superconductor film; and top stabilizer layer disposed above the top silver layer. At least one of the bottom stabilizer layer, bottom silver layer, substrate, buffer film stack, superconductor film, top silver layer, or top stabilizer layer is of a different width, thickness, or material composition in one of the superconductor tapes than in another of the superconductor tapes. These and other embodiments achieve a round superconductor wire having improved current density in high magnetic field applications when made in small diameters. |
| FILED | Monday, October 28, 2019 |
| APPL NO | 17/288838 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358686 | Raminosoa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tsarafidy Raminosoa (Oak Ridge, Tennessee); Jason L. Pries (Oak Ridge, Tennessee); Randy H. Wiles (Oak Ridge, Tennessee); Jonathan P. Wilkins (Oak Ridge, Tennessee) |
| ABSTRACT | A system is provided for transferring power between a stator and a rotor of an excitation system. The stator and the rotor may form part of a rotary transformer that includes a primary winding and a secondary winding, where power is transferred from the primary winding to the secondary winding or conversely from the secondary winding to the primary winding. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318248 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) H01F 38/18 (20130101) Original (OR) Class H01F 38/023 (20130101) H01F 2038/146 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/10 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359146 | Selvamanickam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Venkat Selvamanickam (Houston, Texas); Yongkuan Li (Houston, Texas); Ying Gao (Mason, Ohio) |
| ABSTRACT | A superconductor tape and method for fabricating same are disclosed. Embodiments are directed to a superconductor tape including a substrate and a buffer stack. In one embodiment, the buffer stack includes: an Ion Beam-Assisted Deposition (IBAD) template layer above the substrate; a homo-epitaxial film of MgO or TiN above the IBAD template layer; an epitaxial film of silver above the homo-epitaxial film; and a homo-epitaxial film of LaMnO3 (LMO) above the silver epitaxial film. The superconductor tape also includes a superconductor film above the buffer stack. These and other embodiments achieve a LMO film with substantially improved texture, resulting in a superconductor structure having high critical current and significantly reduced power consumption and cost. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 17/288828 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/183 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02293 (20130101) H01L 31/0392 (20130101) Original (OR) Class H01L 39/248 (20130101) H01L 39/2461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210359484 | Pax et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul H. Pax (Livermore, California); Jay W. Dawson (Livermore, California); Victor V. Khitrov (San Ramon, California); Cody W. Mart (Livermore, California); Michael J. Messerly (Danville, California); Michael Runkel (Livermore, California); Charles X. Yu (Pleasanton, California) |
| ABSTRACT | The present technology provides large mode area optical fibers engineered to have normal dispersion around 1600 nm, enabling high power Raman amplification at eye safer wavelengths. The fibers can have a main core and one or more side cores disposed relative to the main core so that modes of the main core and the one or more side cores hybridize into supermodes with modified dispersion. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317752 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) H01S 3/06716 (20130101) H01S 3/06725 (20130101) H01S 3/06737 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20210353454 | Steele et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John W. Steele (New Hartford, Connecticut); Peter A. Canga (League City, Texas); Barbara M. Peyton (Windsor, Connecticut); Tony Rector (East Granby, Connecticut); Douglas Zupan (La Porte, Texas) |
| ABSTRACT | A system includes a filter device that has, in serial flow order, an adsorbent bed, a biocide filter, and a particle filter. The adsorbent bed includes adsorbent media that is configured to remove organic compounds from feed water that are capable of forming an adherent layer on a porous surface of a sublimator, and the biocide filter contains a halogen-release material. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/388407 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/0085 (20130101) Original (OR) Class A61F 2007/0056 (20130101) Separation B01D 7/00 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 6/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 9/005 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355952 | Gallagher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward J. Gallagher (West Hartford, Connecticut); Byron R. Monzon (Cromwell, Connecticut); Shari L. Bugaj (Haddam, Connecticut) |
| ABSTRACT | A gas turbine engine includes a gear assembly, a bypass flow passage, a fan located upstream of the bypass flow passage, a first shaft and a second shaft, a first turbine coupled through the gear assembly to the fan, a first compressor coupled with the first shaft, and a second turbine coupled with the second shaft. The fan has a bypass ratio of greater than 8.5. The fan includes a hub and a row of fan blades that extend from the hub. The row includes a number (N) of the fan blades that is from 16 to 20, a solidity value (R) at tips of the fan blades, and a ratio of N/R that is from 12.3 to 20. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385150 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/282 (20130101) F01D 15/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) F02C 7/36 (20130101) Jet-propulsion Plants F02K 1/06 (20130101) F02K 3/06 (20130101) Non-positive-displacement Pumps F04D 29/023 (20130101) Original (OR) Class F04D 29/053 (20130101) F04D 29/325 (20130101) F04D 29/388 (20130101) F04D 29/526 (20130101) F04D 29/563 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/36 (20130101) F05D 2220/323 (20130101) F05D 2220/327 (20130101) F05D 2260/4031 (20130101) F05D 2300/603 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356625 | Mecikalski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John R. Mecikalski (Madison, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John R. Mecikalski (Madison, Alabama) |
| ABSTRACT | A weather forecasting system has a data processing system that receives weather data from one or more sources and processes such data in conjunction with a weather forecasting algorithm in order to forecast weather for one or more geographic regions. In this regard, the weather data is input into a machine learning algorithm, which applies learned weights and relationships to the inputs in order to calculate at least one score indicating a probability that precipitation or other weather event will occur in the future within a certain time period (e.g., within the next 1 hour or some other unit of time) in one or more geographic regions. For each such geographic region, the weather forecasting logic may also predict the extent to which rain or other precipitation, lightning, or other weather event will occur during the time period. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162517 |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/10 (20130101) G06F 30/20 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 2207/30192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358714 | GANDHIRAMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Space Foundry Inc. (Los Gatos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramprasad GANDHIRAMAN (San Jose, California); Fergal John O'MOORE (Los Gatos, California); Lief Niklas Dennis NORDLUND (Menlo Park, California); Arlene Lynette LOPEZ (Long Beach, California) |
| ABSTRACT | Described herein are apparatus and methods of printing in the presence of plasma. The apparatus includes a modular print head comprising an inlet module, a plasma module with movable electrode configurations, and a nozzle module. The modular design of the print head allows for printing on and treatment of surfaces in many different applications. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176905 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/10 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360440 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386179 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360441 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386206 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360443 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443663 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360444 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Pallisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443709 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360445 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443751 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210360841 | THOMSEN, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DONALD L. THOMSEN, III (YORKTOWN, Virginia); ROBERTO J. CANO (YORKTOWN, Virginia); BRIAN J. JENSEN (WILLIAMSBURG, Virginia); STEPHEN J. HALES (POQUOSON, Virginia); JOEL A. ALEXA (HAMPTON, Virginia) |
| ABSTRACT | Aspects relate to building Z-graded radiation shielding and covers. In one aspect, the method includes: providing a substrate surface having about medium Z-grade; plasma spraying a first metal having higher Z-grade than the substrate surface; and infusing a polymer layer to form a laminate. In another aspect, the method includes electro/electroless plating a first metal having higher Z-grade than the substrate surface. In other aspects, the invention provides methods of improving an existing electronics enclosure to build a Z-graded radiation shield by applying a temperature controller to at least part of the enclosure and affixing at least one layer of a first metal having higher Z-grade than the enclosure. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386208 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/48 (20130101) B29C 70/88 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/02 (20130101) C23C 4/08 (20130101) C23C 4/18 (20130101) C23C 28/00 (20130101) C23C 28/021 (20130101) C23C 28/023 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 13/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/4902 (20150115) Y10T 29/49002 (20150115) Y10T 29/49224 (20150115) Y10T 442/259 (20150401) Y10T 442/2041 (20150401) Y10T 442/2049 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20210356306 | Parziale |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Nick Parziale (Ridgewood, New Jersey) |
| ABSTRACT | Methods and apparatus for tracking fluid flows are disclosed. Fast-moving fluids can be non-invasively tracked, including those at supersonic and hypersonic speeds. To track such flows, atoms of an inert gas can be introduced into the fluid. To monitor the tracer, a laser excites a series of molecules along a “write line,” which can be tracked by a series of cameras in order to estimate flow velocity. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/320112 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/704 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/248 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358627 | Longmire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Medable Inc. (Palo Alto, California) |
| ASSIGNEE(S) | Medable Inc. (PALO ALTO, California) |
| INVENTOR(S) | Michelle Longmire (PALO ALTO, California); Ingrid Oakley-Girvan (Henderson, California); NICK MOSS (Los Alamos, New Mexico) |
| ABSTRACT | A method and system for connecting, capturing, managing and predicting outcomes for an improved care for home based patients by collecting data from caregivers and home-based patients. The method and system implemented as a mobile technology is more efficient and effective method for delivering healthcare that will ease the caregiving burden. Providing resources and information to communicate, capture and deliver by the caregivers (formal and informal), patients and healthcare providers communicate helps integrate essential data and care. Through the use of this mobile technology and associated devices vital information from informal caregivers, which is currently not regularly used in remotely located patients, can be captured and implemented in the decisions and adjustments to patients' care plans. In addition, the technology helps with adherence of patient specific treatment guidelines for home-based patients. |
| FILED | Sunday, March 14, 2021 |
| APPL NO | 17/200866 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 10/65 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 80/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358660 | Majkic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Goran Majkic (Houston, Texas); Anis Ben Yahia (Houston, Texas); Wenbo Luo (Houston, Texas); Venkat Selvamanickam (Houston, Texas); Soumen Kar (Houston, Texas) |
| ABSTRACT | A round superconductor wire and method for fabricating same are disclosed. Embodiments are directed to a round superconductor wire including at least two superconductor tapes wound on a wire former. Each superconductor tape includes: bottom stabilizer and silver layers; substrate disposed above the bottom silver layer; buffer film stack disposed above the substrate; superconductor film disposed above the buffer film stack; top silver layer disposed above the superconductor film; and top stabilizer layer disposed above the top silver layer. At least one of the bottom stabilizer layer, bottom silver layer, substrate, buffer film stack, superconductor film, top silver layer, or top stabilizer layer is of a different width, thickness, or material composition in one of the superconductor tapes than in another of the superconductor tapes. These and other embodiments achieve a round superconductor wire having improved current density in high magnetic field applications when made in small diameters. |
| FILED | Monday, October 28, 2019 |
| APPL NO | 17/288838 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210358714 | GANDHIRAMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Space Foundry Inc. (Los Gatos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramprasad GANDHIRAMAN (San Jose, California); Fergal John O'MOORE (Los Gatos, California); Lief Niklas Dennis NORDLUND (Menlo Park, California); Arlene Lynette LOPEZ (Long Beach, California) |
| ABSTRACT | Described herein are apparatus and methods of printing in the presence of plasma. The apparatus includes a modular print head comprising an inlet module, a plasma module with movable electrode configurations, and a nozzle module. The modular design of the print head allows for printing on and treatment of surfaces in many different applications. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176905 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/10 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20210354109 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355512 | REDDY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts); Western Washington University (Bellingham, Washington); Marine Biological Laboratory (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts); Western Washington University (Bellingham, Washington); Marine Biological Laboratory (Woods Hole, Massachusetts) |
| INVENTOR(S) | CHRISTOPHER M. REDDY (WOODS HOLE, Massachusetts); GREGORY W. O'NEIL (BELLINGHAM, Wisconsin); SCOTT R. LINDELL (WOODS HOLE, Massachusetts) |
| ABSTRACT | A method comprising a series of selective extraction techniques for the parallel production of biodiesel and isolation of several valuable co-products including an alkenone hydrocarbon mixture of the kerosene/jet fuel range (primarily C10-, C12-, and C17-hydrocarbons) and fucoxanthin, a high-valued carotenoid, from the marine alkenone-producing microalgae Isochrysis. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/388298 |
| CURRENT CPC | Heterocyclic Compounds C07D 303/32 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/19 (20130101) C10L 1/185 (20130101) C10L 1/1802 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/003 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/26 (20130101) C12P 7/649 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210356398 | Yuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Baohong Yuan (Arlington, Texas); Tingfeng Yao (Arlington, Texas) |
| ABSTRACT | A method of imaging described herein comprises (a) disposing ultrasound-switchable fluorophores within an environment; (b) exposing the environment to ultrasound to create a first activation region within the environment; (c) disposing the fluorophores within the first activation region to switch the fluorophores from an off state to an on state; (d) irradiating the environment to excite the fluorophores within the first activation region; (e) detecting photoluminescence from the excited fluorophores at a first optical spot on an exterior surface of the environment; (f) subsequently creating a second activation region within the environment; (g) switching fluorophores within the second activation region to an on state; (h) exciting the fluorophores in the on state within the second activation region; and (i) detecting photoluminescence from the excited fluorophores within the second activation region at a second optical spot on the exterior surface, wherein the first and second optical spots are optically resolvable. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 17/286126 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2021/6439 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357480 | Hoff |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clean Power Research, L.L.C. (Napa, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas E. Hoff (Napa, California) |
| ABSTRACT | Long-term photovoltaic system degradation can be predicted through a simple, low-cost solution. The approach requires the configuration specification for a photovoltaic system, as well as measured photovoltaic production data and solar irradiance, such as measured by a reliable third party source using satellite imagery. Note the configuration specification can be derived. This information is used to simulate photovoltaic power production by the photovoltaic system, which is then evaluated against the measured photovoltaic production data. The simulated production is adjusted to infer degradation that can be projected over time to forecast long-term photovoltaic system degradation. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379170 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20210352856 | MARTIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Active Influence and Scientific Management, SP (San Angelo, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DANIEL E. MARTIN (COLLEGE STATION, Texas); Arquimedes Ruiz-Columbie (San Angelo, Texas) |
| ABSTRACT | The system uses a specifically modified spray assembly to spray electrically charged fluid into selected clouds. In addition to rain enhancement, the system is also designed for snow enhancement, hail suppression, fog dissipation, and smog remediation. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387348 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 15/00 (20130101) Original (OR) Class Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/0255 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355499 | Simon |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Anne Elizabeth Simon (Bowie, Maryland) |
| ABSTRACT | The present disclosure relates to a single stranded RNA vector suitable for introducing a therapeutic agent, such as a peptide, a protein or a small RNA, into a host plant. The vector does not encode for any movement protein or coat protein, but is capable of capable of systemic and phloem-limited movement and replication within the host plant. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317596 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355500 | GLEASON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cynthia GLEASON (Pullman, Washington); Lei ZHANG (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure provides bacterial strains modified for secretion of a plant defense elicitor peptide. More particularly, the bacterial strain comprises an exogenous sequence encoding the plant defense elicitor peptide. Vectors and methods utilizing the described bacterial strains are also provided. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/320414 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8285 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/125 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
20210353833 — NERVE REPAIR SCAFFOLDS HAVING HIGH MICROCHANNEL VOLUME AND METHODS FOR MAKING THE SAME
| US 20210353833 | SAKAMOTO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. SAKAMOTO (Ann Arbor, Michigan); Dena SHAHRIARI (Woodland Hills, California); Mark H. TUSZYNSKI (La Jolla, California); Wendy CAMPANA (La Jolla, California); Yacov KOFFLER (San Diego, California) |
| ABSTRACT | Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels. |
| FILED | Thursday, July 22, 2021 |
| APPL NO | 17/382786 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355154 | Viglianti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin L. Viglianti (Ann Arbor, Michigan); Allen F. Brooks (Ann Arbor, Michigan); Peter J. H. Scott (Ypsilanti, Michigan); Stephen Thompson (Ann Arbor, Michigan); Stefan Verhoog (Ann Arbor, Michigan); Milton D. Gross (Ann Arbor, Michigan); Wade P. Winton (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are halogenated cholesterol analogues, including methods of making and using the same. Also provided are methods of making radiolabeled cholesterol analogues including admixing an epoxide with a fluorine-18 source under conditions to form a radiofluorinated cholesterol analogue. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/250891 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Steroids C07J 9/00 (20130101) Original (OR) Class C07J 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210357021 | Major et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Justin Major (Chicago, Illinois); Stefania Fatone (Chicago, Illinois) |
| ABSTRACT | A system to perform neurorehabilitation includes a display that is visible to a user. The system also includes a camera operatively coupled to the display and configured to capture a walking surface upon which the user is walking. The system further includes a processor operatively coupled to the display and to the camera. The processor is configured to project a virtual object onto the walking surface such that the virtual object is visible to the user on the display. The processor is also configured to monitor user movement relative to the virtual object. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318520 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 71/0622 (20130101) A63B 2071/0638 (20130101) A63B 2071/0666 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 19/006 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20210353549 | Murphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William L. Murphy (Waunakee, Wisconsin); Andrew Salim Khalil (Madison, Wisconsin); Xiaohua Yu (Mansfield Center, Connecticut) |
| ABSTRACT | Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral Layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379351 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/501 (20130101) Original (OR) Class A61K 38/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210354083 | Pavlish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Midwest Energy Emissions Corp (Corsicana, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John H. Pavlish (East Grand Forks, Minnesota); Edwin S. Olson (Grand Forks, North Dakota); Michael J. Holmes (Thompson, North Dakota) |
| ABSTRACT | Various embodiments disclosed relate to sorbents for the oxidation and removal of mercury. The present invention includes removing mercury from a mercury-containing gas using a halide-promoted and optionally ammonium-protected sorbent that can include carbon sorbent, non-carbon sorbent, or a combination thereof. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209720 |
| CURRENT CPC | Separation B01D 53/10 (20130101) B01D 53/64 (20130101) Original (OR) Class B01D 53/83 (20130101) B01D 2251/108 (20130101) B01D 2251/206 (20130101) B01D 2253/102 (20130101) B01D 2257/602 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/04 (20130101) B01J 20/10 (20130101) B01J 20/12 (20130101) B01J 20/20 (20130101) B01J 20/027 (20130101) B01J 20/041 (20130101) B01J 20/043 (20130101) B01J 20/106 (20130101) B01J 20/223 (20130101) B01J 20/0262 (20130101) B01J 20/3416 (20130101) B01J 20/28004 (20130101) B01J 2220/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20210354144 | SHENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian SHENG (College Station, Texas); Andrew R. WHITE (College Station, Texas); Maryam JALALI (College Station, Texas) |
| ABSTRACT | The present disclosure relates to a microfluidic channel composition configured for establishing a liquid-liquid interface and a microfluidic platform comprising the microfluidic channel composition. More particularly, the present disclosure includes a microfluidic platform for analyzing oil-aqueous interface interactions and methods utilizing the platform, for instance to evaluate environmental settings where oil may be present. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318763 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502784 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2300/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20210355440 | CHOU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| INVENTOR(S) | Stella CHOU (Bryn Mawr, Pennsylvania); Connie WESTHOFF (New York, New York) |
| ABSTRACT | Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/757815 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20210355420 | Ling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jian Ling (Spring Branch, Texas); Kreg A. Zimmern (San Antonio, Texas); Michael C. Milone (Philadelphia, Pennsylvania) |
| ABSTRACT | Described herein is a beads-free bioprocessor as an automated and cost-effective T cell processing and manufacturing platform. T cells are a core component in CAR T cell therapies for cancer treatment, but are difficult to manufacture to scale in clinically relevant quantities. The 3D bioprocessor provides an alternative device that is scalable, beads-free, easy-to-use, and cost-effective for using CAR T cell therapy in cancer immunotherapy. Besides CAR T cell application, this platform technology has potential for many other applications such as cancer cell isolation. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872823 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 25/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20210354109 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 20210355197 | LANDAIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elise LANDAIS (La Jolla, California); Devin SOK (San Diego, California) |
| ABSTRACT | The present disclosure relates to anti-HIV Env antibodies and their use in the treatment or prevention of HIV/AIDS. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 17/287188 |
| CURRENT CPC | Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20210359666 | Keane |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zachary Kyle Keane (Baltimore, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (FALLS CHURCH, Virginia) |
| INVENTOR(S) | Zachary Kyle Keane (Baltimore, Maryland) |
| ABSTRACT | A capacitively-driven tunable coupler includes a coupling capacitor connecting an open end of a quantum object (i.e., an end of the object that cannot have a DC path to a low-voltage rail, such as a ground node, without breaking the functionality of the object) to an RF SQUID having a Josephson element capable of providing variable inductance and therefore variable coupling to another quantum object. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/383779 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/04 (20130101) Original (OR) Class Pulse Technique H03K 3/38 (20130101) H03K 19/1952 (20130101) H03K 19/017509 (20130101) H03K 19/017545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, November 18, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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