FedInvent Patents

Patent Details for Tuesday, June 01, 2021

This page was updated on Saturday, July 17, 2021 at 01:22 AM GMT

Department of Health and Human Services (HHS)

11020005 — Neuromechanical algometer

US 11020005	Fitzgerald et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Rehabilitation Institute of Chicago (Chicago, Illinois)
ASSIGNEE(S)	Rehabilitation Institute of Chicago (Chicago, Illinois)
INVENTOR(S)	Colleen M. Fitzgerald (LaGrange, Illinois); Yasin Y. Dhaher (Mount Prospect, Illinois)
ABSTRACT	Systems and methods for the diagnosis of chronic pain are disclosed. An algometer comprising a pressure sensor and electrode is disclosed. The algometer may be used to measure pressure applied by a clinician at a location on a patient's body, along with EMG signals emanating from the same location of the patient. Further, a pain trigger operable by the patient may be used in coordination with the algometer. Data from the algometer and pain trigger are transmitted to a computing device and display for rendering and analysis of patient data, leading to improved diagnosis.
FILED	Friday, August 10, 2018
APPL NO	16/100928
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0053 (20130101) Original (OR) Class A61B 5/296 (20210101) A61B 5/483 (20130101) A61B 5/4827 (20130101) A61B 5/6843 (20130101) A61B 5/6885 (20130101) A61B 2560/0425 (20130101) A61B 2560/0462 (20130101) A61B 2560/0468 (20130101) A61B 2562/0247 (20130101)
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11020006 — Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data

US 11020006	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Lihong V. Wang (Arcadia, California); Liming Nie (St. Louis, Missouri); Xin Cai (St. Louis, Missouri); Konstantin Maslov (Pasadena, California); Mark A. Anastasio (St. Louis, Missouri); Chao Huang (St. Louis, Missouri); Robert W. Schoonover (St. Louis, Missouri)
ABSTRACT	Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.
FILED	Friday, October 18, 2013
APPL NO	14/436581
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/725 (20130101) A61B 5/4839 (20130101) A61B 5/4848 (20130101) A61B 5/7282 (20130101) A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 2576/026 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/2418 (20130101)
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11020015 — System and method for rapid examination of vasculature and particulate flow using laser speckle contrast imaging

US 11020015	Rege et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	VASOPTIC MEDICAL, INC. (Baltimore, Maryland)
ASSIGNEE(S)	Vasoptic Medical, Inc. (Baltimore, Maryland)
INVENTOR(S)	Abhishek Rege (Baltimore, Maryland); M. Jason Brooke (University Park, Maryland); Kartikeya Murari (Calgary, Canada); Yusi Liu (Rockville, Maryland)
ABSTRACT	Examination of the structure and function of blood vessels is an important means of monitoring the health of a subject. Such examination can be important for disease diagnoses, monitoring specific physiologies over the short- or long-term, and scientific research. This disclosure describes technology and various embodiments of a system and method for imaging blood vessels and the intra-vessel blood flow, using at least laser speckle contrast imaging, with high speed so as to provide a rapid estimate of vessel-related or blood flow-related parameters.
FILED	Friday, October 07, 2016
APPL NO	15/767057
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/14 (20130101) A61B 3/0075 (20130101) A61B 3/0083 (20130101) A61B 3/1208 (20130101) A61B 3/1233 (20130101) A61B 5/02 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) Original (OR) Class A61B 5/721 (20130101) A61B 5/742 (20130101) A61B 5/7207 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101)
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11020020 — Variable ventilation as a diagnostic tool for assessing lung mechanical function

US 11020020	Smith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (Burlington, Vermont)
ASSIGNEE(S)	University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S)	Bradford J. Smith (Burlington, Vermont); Jason H. T. Bates (S. Burlington, Vermont)
ABSTRACT	Systems and methods for determining lung recruitment/derecruitment dynamics of an individual are disclosed. The disclosed embodiments advantageously use variable ventilation of the individual to determine lung dynamics without necessitating additional, potentially harmful ventilation maneuvers.
FILED	Monday, February 23, 2015
APPL NO	15/120902
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/087 (20130101) Original (OR) Class A61B 5/091 (20130101) A61B 5/0816 (20130101) A61B 5/4836 (20130101) A61B 5/7278 (20130101) A61B 5/7282 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0069 (20140204)
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11020025 — Automatically classifying animal behavior

US 11020025	Datta et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD) Office of the Director (NIHOD)
APPLICANT(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Sandeep Robert Datta (Newton, Massachusetts); Alexander Bame Wiltschko (Somerville, Massachusetts); Matthew J. Johnson (Hillsborough, California)
ABSTRACT	Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior.
FILED	Tuesday, October 11, 2016
APPL NO	15/767544
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/1123 (20130101) A61B 5/1128 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2576/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/209 (20130101) G06K 9/00335 (20130101) G06K 9/6247 (20130101) G06K 9/6297 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101)
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11020054 — Diagnostic and therapeutic splints

US 11020054	Pritchard et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Emily Pritchard (Tallahassee, Florida); Mina-Michael Barsoum (Tallahassee, Florida); Judy Delp (Tallahassee, Florida); Josh Maraj (Tallahassee, Florida); Kazuki Hotta (Niigata, Japan)
ABSTRACT	Splints for diagnostic and/or therapeutic purposes are disclosed. In one aspect, the present disclosure relates to a splint system for diagnostic and/or therapeutic functions for a patient with a vascular impairment. In one embodiment, the splint system includes a splint having: a leg supporting portion and a foot supporting portion, that are configured to support and secure the leg and foot of the patient; a locally and/or remotely controllable portion for setting a dorsiflexion angle of the foot of the patient, including electrical and/or mechanical controls and one or more actuators for setting of the dorsiflexion angle, for providing treatment to improve vascular function; and a plurality of physiological parameter sensors for measuring physiological parameters of the leg and/or foot of the patient, wherein the physiological parameters are associated with vascular function in the leg and/or foot of the patient.
FILED	Thursday, November 15, 2018
APPL NO	16/192423
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/026 (20130101) A61B 5/0295 (20130101) A61B 5/1036 (20130101) A61B 5/1071 (20130101) A61B 5/02055 (20130101) A61B 5/02233 (20130101) A61B 5/02416 (20130101) A61B 5/4836 (20130101) A61B 5/6812 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 5/14552 (20130101) A61B 7/04 (20130101) A61B 8/02 (20130101) A61B 8/04 (20130101) A61B 8/06 (20130101) A61B 8/461 (20130101) A61B 8/488 (20130101) A61B 8/4209 (20130101) A61B 8/4227 (20130101) A61B 8/4427 (20130101) A61B 8/5223 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0127 (20130101) A61F 5/0585 (20130101) A61F 2005/0155 (20130101) A61F 2005/0167 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0266 (20130101) A61H 2201/165 (20130101) A61H 2201/0173 (20130101) A61H 2201/0192 (20130101) A61H 2201/1215 (20130101) A61H 2201/1642 (20130101) A61H 2201/5007 (20130101) A61H 2201/5025 (20130101) A61H 2201/5069 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) A61H 2209/00 (20130101) A61H 2230/00 (20130101) A61H 2230/30 (20130101) A61H 2230/50 (20130101) A61H 2230/207 (20130101)
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11020077 — Simultaneous CT-MRI image reconstruction

US 11020077	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)	Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S)	Ge Wang (Loudonville, New York); Yan Xi (Troy, New York); Wenxiang Cong (Albany, New York); Jun Zhao (Shanghai, China PRC)
ABSTRACT	Novel and advantageous systems and method for obtaining and/or reconstructing simultaneous computed tomography (CT)-magnetic resonance imaging (MRI) images are provided. Structural coupling (SC) and compressive sensing (CS) techniques can be combined to unify and improve CT and MRI reconstruction. A bidirectional image estimation method can be used to connect images from different modalities, with CT and MRI data serving as prior knowledge to each other to produce better CT and MRI image quality than would be realized with individual reconstruction.
FILED	Wednesday, September 14, 2016
APPL NO	15/759326
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/055 (20130101) A61B 6/032 (20130101) A61B 6/035 (20130101) A61B 6/4417 (20130101) A61B 6/5205 (20130101) A61B 6/5247 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3815 (20130101) G01R 33/4812 (20130101) G01R 33/5608 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) G06T 2211/424 (20130101)
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11020404 — Use of CDK9 and BRD4 inhibitors to inhibit inflammation

US 11020404	Haudenschild et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents Of The University Of California, Davis (Oakland, California)
INVENTOR(S)	Dominik Haudenschild (Davis, California); Jasper Yik (Elk Grove, California)
ABSTRACT	Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit and/or prevent cartilage degradation and systemic traumatic inflammation. A combination of CDK9 inhibitors and BRD4 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. A combination of CDK9 inhibitors and BRD4 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED	Thursday, May 23, 2019
APPL NO	16/421218
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 31/445 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/5513 (20130101) Original (OR) Class A61K 31/5513 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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11020422 — Cyclodextrin for the treatment of lysosomal storage diseases

US 11020422	McKew et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)
INVENTOR(S)	John McKew (Poolesville, Maryland); Wei Zheng (Potomac, Maryland); Miao Xu (Hangzhou, China PRC); Manju Swaroop (Gaithersburg, Maryland); Juan J. Marugan (Gaithersburg, Maryland)
ABSTRACT	The invention provides for methods of treating lysosomal storage disorders and/or reduction of non-cholesterol lipids, using cyclodextrin compounds, including in combination with other therapeutics, including vitamin E.
FILED	Monday, June 12, 2017
APPL NO	15/620753
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/355 (20130101) A61K 31/355 (20130101) A61K 31/724 (20130101) Original (OR) Class A61K 31/724 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0012 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101)
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11020426 — Electrolyte formulations and uses thereof

US 11020426	Poelzing et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
ASSIGNEE(S)	VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
INVENTOR(S)	Steven Poelzing (Roanoke, Virginia); David Ryan King (Roanoke, Virginia)
ABSTRACT	Described herein are low sodium formulations. In some embodiments, the low sodium formulations can contain an effective concentration of sodium and an effective concentration of calcium. The low sodium formulations can be provided as combination kit that can include, in some embodiments, a low sodium formulation and a defibrillation device. Also described herein are methods of administering the low sodium formulation to a subject in need thereof and performing cardiac resuscitation and/or defibrillation on the subject in need thereof.
FILED	Thursday, November 08, 2018
APPL NO	16/184291
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) A61K 33/06 (20130101) Original (OR) Class A61K 33/08 (20130101) A61K 33/10 (20130101) A61K 33/14 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3904 (20170801)
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11020430 — Immune cells with DNMT3A gene modifications and methods related thereto

US 11020430	Ahmed et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Emory University (Atlanta, Georgia); St. Jude Children's Hospital, Inc. (Memphis, Tennessee)
ASSIGNEE(S)	Emory University (Atlanta, Georgia); St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee)
INVENTOR(S)	Rafi Ahmed (Atlanta, Georgia); Benjamin Youngblood (Decatur, Georgia)
ABSTRACT	This disclosure relates to the genetic modification of DNMT3A gene in immune cells. In certain embodiments, the modified immune cells may be used in adoptive T cells therapies to enhance immune responses against cancer or chronic infections. In certain embodiments, the disclosure relates to deleting, changing, or inserting nucleotides within the DNMT3A gene in immune cells, e.g., human CD8 T cells, such that the DNMT3A gene product does not function for methylation. In certain embodiments, modification of the DNMT3A gene provides an improvement in antigen-specific T cells functions and/or an enhancement of the longevity of the cells.
FILED	Friday, November 04, 2016
APPL NO	15/773783
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 9/1007 (20130101) C12N 2510/00 (20130101) C12N 2740/16033 (20130101) C12N 2740/16111 (20130101) Enzymes C12Y 201/01037 (20130101)
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11020443 — Modulation of AAV vector transgene expression

US 11020443	Esteves et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Miguel Sena Esteves (Westford, Massachusetts); Cara Weismann (Worcester, Massachusetts); Diane Golebiowski (Lexington, Massachusetts); Lorelei Stoica (Worcester, Massachusetts)
ABSTRACT	Aspects of the invention relate to recombinant adeno-associated viruses (rAAVs). In some aspects, the rAAVs comprise artificial genetic regulatory elements that modulate transgene expression. In some aspects, the disclosure relates to the treatment of lysosomal storage disorders.
FILED	Wednesday, April 20, 2016
APPL NO	15/567847
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/761 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 48/0058 (20130101) A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 43/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) C12N 9/2471 (20130101) C12N 15/86 (20130101) C12N 15/861 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 302/01023 (20130101) C12Y 302/01052 (20130101)
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11020456 — Methods for modulating an inflammatory response

US 11020456	Hunter et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Christopher A. Hunter (Philadelphia, Pennsylvania); Alejandro Villarino (Philadelphia, Pennsylvania)
ABSTRACT	The inventive subject matter relates to novel methods for modulating an immune response in an animal, which comprises administering to said animal an effective amount of an agent that increases IL-27R/WSX-1 activity. Further, the inventive subject matter relates to pharmaceutical compositions comprising an effective amount of an agent that increases IL-27R/WSX-1 activity.
FILED	Tuesday, January 30, 2018
APPL NO	15/883879
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class A61K 38/208 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2866 (20130101) C07K 2317/76 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11020463 — Method of determining cellular protein homeostasis

US 11020463	Conklin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The J. David Gladstone Institutes (San Francisco, California); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Bruce R. Conklin (San Francisco, California); Luke Judge (San Francisco, California)
ABSTRACT	The present invention provides assays and compositions to identify the risk of toxicity in a patient population with genotypic variations in specific proteins and/or protein complexes within the patient population.
FILED	Monday, August 08, 2016
APPL NO	15/750495
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/57 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) C12Q 1/6881 (20130101) C12Q 2600/106 (20130101) C12Q 2600/142 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5061 (20130101) G01N 33/5073 (20130101)
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11020482 — Methods and compositions related to inhibition of viral entry

US 11020482	Francis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S)	THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S)	J. Nicholas Francis (Salt Lake City, Utah); Joseph S. Redman (Salt Lake City, Utah); Michael S. Kay (Salt Lake City, Utah)
ABSTRACT	Disclosed herein are compositions and methods for inhibiting viral entry.
FILED	Wednesday, August 21, 2019
APPL NO	16/547383
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/542 (20170801) A61K 47/554 (20170801) A61K 47/643 (20170801) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101)
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11020488 — Pyrroloquinolin compounds and methods of using same

US 11020488	Crews et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California); Henry Ford Health System (Detroit, Michigan)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Henry Ford Health System (Detroit, Michigan)
INVENTOR(S)	Phillip Crews (Santa Cruz, California); Frederick A. Valeriote (Washington, Michigan); Sheng Lin (Beijing, China PRC); Erin P. McCauley (Santa Cruz, California); Nicholas Lorig-Roach (Santa Cruz, California); Karen Tenney (Santa Cruz, California)
ABSTRACT	Provided are pyrroloquinolin compounds of formula (1) or (II). In certain aspects, the pyrroloquinolin compounds are therapeutic, e.g., for treating a cell proliferative disorder. Also provided are conjugates that include the pyrroloquinolin compounds of the present disclosure. Compositions, e.g., pharmaceutical compositions, that include the pyrroloquinolin compounds and conjugates of the present disclosure are also provided. Further provided are therapeutic methods involving the administration of the pyrroloquinolin compounds, conjugates or compositions of the present disclosure. Kits that include the pyrroloquinolin compounds, conjugates or compositions are also provided.
FILED	Tuesday, March 13, 2018
APPL NO	16/493690
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 47/6803 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/06 (20130101)
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11020489 — Immunoconjugates with an intracellularly-cleavable linkage

US 11020489	Govindan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Immunomedics, Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Immunomedics, Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Serengulam V. Govindan (Summit, New Jersey); Sung-Ju Moon (New Providence, New Jersey); David M. Goldenberg (Mendham, New Jersey)
ABSTRACT	The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates.
FILED	Monday, April 06, 2020
APPL NO	16/841345
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6841 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 47/6855 (20170801) A61K 47/6857 (20170801) A61K 47/6861 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 491/22 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/1063 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/3046 (20130101) C07K 16/3076 (20130101) C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/40 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/94 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11020494 — Animal models for nonalcoholic fatty liver disease

US 11020494	Peterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	CROWN BIOSCIENCE INC. (TAICANG) (Taicang, China PRC)
ASSIGNEE(S)	CROWN BIOSCIENCE INC. (TAICANG) (Jiangsu, China PRC)
INVENTOR(S)	Richard Peterson (Indianapolis, Indiana); Charles Van Jackson (Greenfield, Indiana); Gao Sun (Shanghai, China PRC); Guodong Zhang (Taicang, China PRC); Yixin (Jim) Wang (Lafayette, California)
ABSTRACT	The present disclosure provides non-human animal models of non-alcoholic fatty liver disease (NAFLD). Also provided are methods for producing the non-human animal models and uses of the non-human animal models to screen and evaluate agents for treating or preventing NAFLD.
FILED	Thursday, June 21, 2018
APPL NO	16/013953
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) A01K 2207/25 (20130101) A01K 2227/105 (20130101) A01K 2267/035 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class
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11020497 — Rod-shaped plant virus nanoparticles as imaging agent platforms

US 11020497	Steinmetz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Nicole Steinmetz (San Diego, California); Michael Bruckman (Cleveland, Ohio)
ABSTRACT	A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
FILED	Tuesday, October 02, 2018
APPL NO	16/149828
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/1884 (20130101) A61K 49/1896 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/00031 (20130101)
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11020524 — Peristaltic micropumps and fluid delivery devices that incorporate them

US 11020524	Borkholder et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	David A. Borkholder (Canandaigua, New York); Farzad Forouzandeh (Rochester, New York); Robert Nash Carter (Honeoye Falls, New York); Denis Roger Cormier (Pittsford, New York); Joseph P. Walton (Tampa, Florida); Robert Dana Frisina (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida); Rochester Institute of Technology (Rochester, New York)
INVENTOR(S)	David A. Borkholder (Canandaigua, New York); Farzad Forouzandeh (Rochester, New York); Robert Nash Carter (Honeoye Falls, New York); Denis Roger Cormier (Pittsford, New York); Joseph P. Walton (Tampa, Florida); Robert Dana Frisina (Tampa, Florida)
ABSTRACT	In one embodiment, a peristaltic micropump comprising a substrate having a first side and a second side, a microtube that extends across the first side of the substrate, and multiple pump actuators formed on the first side of the substrate and positioned adjacent to the microtube at discrete, spaced positions along the length of the microtube, wherein the micropump is configured to sequentially actuate the pump actuators so as to create peristaltic action that drives fluid contained in the microtube along the length of the tube.
FILED	Monday, February 20, 2017
APPL NO	15/437356
ART UNIT	3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14228 (20130101) A61M 5/14276 (20130101) Original (OR) Class A61M 2005/14208 (20130101) A61M 2205/50 (20130101) A61M 2205/0216 (20130101) A61M 2205/0244 (20130101) A61M 2205/3368 (20130101) A61M 2205/3523 (20130101) A61M 2205/3673 (20130101) A61M 2205/8206 (20130101)
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11020593 — System and method for enhancing the binaural representation for hearing-impaired subjects

US 11020593	Brown
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Arizona Board of Regents Acting for and on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Christopher A. Brown (Pittsburgh, Pennsylvania)
ABSTRACT	A method of enhancing binaural representation for a subject includes receiving a first signal and a second signal in response to a plurality of sound sources, generating a number of estimated interaural time differences using the first signal and the second signal, converting each of the number of estimated interaural time differences to a corresponding interaural level difference, using one or more of the corresponding interaural level differences to generate an adjusted first signal, and using the adjusted first signal to generate a number of signals delivered to the subject for enhancing the hearing of the subject.
FILED	Friday, July 15, 2016
APPL NO	15/211173
ART UNIT	2651 — Videophones and Telephonic Communications
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36038 (20170801) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/43 (20130101) H04R 25/505 (20130101) H04R 25/552 (20130101) H04R 2430/03 (20130101) Stereophonic Systems H04S 2420/01 (20130101) H04S 2420/07 (20130101)
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11020601 — Accessory for external cardiac defibrillation, pacing and monitoring physiological signals/health data in the presence of electromagnetic interference

US 11020601	Shusterman
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Vladimir Shusterman (Pittsburgh, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S)	Vladimir Shusterman (Pittsburgh, Pennsylvania)
ABSTRACT	This accessory adapts external cardiac defibrillation systems to enable safe defibrillation, pacing, and cardioversion inside the MRI bore with minimal effect on MR image quality. Commercially available external defibrillators are not designed to work in the MRI environment. An MR-compatible defibrillator is needed to safely perform cardiovascular MRI, in particular MR-guided interventional cardiovascular procedures, such as cardiac electrophysiology studies and cardiac catheterization. This accessory includes nonmagnetic defibrillator housing with MRI safety features, provides interface for MRI-compatible physiological monitoring, and optimizes defibrillator operation for the MRI environment. The accessory may include MRI-compatible modules for monitoring/recording electrocardiogram, blood pressure, pulse oximetry, and other physiological signals. It may also include a wireless transmitter and at least one module for electrical energy generation and/or stimulation.
FILED	Wednesday, April 25, 2018
APPL NO	15/963095
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0006 (20130101) A61B 5/021 (20130101) A61B 5/0024 (20130101) A61B 5/053 (20130101) A61B 5/055 (20130101) A61B 5/0205 (20130101) A61B 5/0263 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/7203 (20130101) A61B 5/7217 (20130101) A61B 5/7221 (20130101) A61B 5/7225 (20130101) A61B 5/7282 (20130101) A61B 5/14551 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3625 (20130101) A61N 1/3718 (20130101) A61N 1/3904 (20170801) Original (OR) Class A61N 1/3931 (20130101) A61N 1/3993 (20130101) A61N 1/36031 (20170801) A61N 1/36139 (20130101) Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101)
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11020610 — Positioning device for use in therapeutic treatment

US 11020610	Brezinski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Little Sparrows Technologies LLC (Winchester, Massachusetts)
ASSIGNEE(S)	LITTLE SPARROWS TECHNOLOGIES INC. (Winchester, Massachusetts)
INVENTOR(S)	Donna Brezinski (Winchester, Massachusetts); Gary Gilbert (Winchester, Massachusetts)
ABSTRACT	Disclosed is a positioning device for use in a compound portable phototherapy device to contain and enhance therapeutic treatment to a subject. The positioning device comprises an inner surface composed of a non-porous, light reflective material, as well as an outer surface that may be opaque. Use of the positioning device in conjunction with a phototherapy device secures advantages of increased incident light directed on a subject and a controlled thermal environment for the subject. The positioning device may be portable and may be pliable, capable of being rolled or compressed. The positioning device may optionally include a visor, venting, and stabilizing cushioning. The positioning device may optionally include a thermal regulation element.
FILED	Wednesday, June 29, 2016
APPL NO	15/739319
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/08 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0621 (20130101) Original (OR) Class A61N 2005/0638 (20130101) A61N 2005/0663 (20130101) A61N 2005/0666 (20130101) A61N 2005/0667 (20130101)
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11020617 — Methods and systems for peripheral nerve modulation using non ablative focused ultrasound with electromyography (EMG) monitoring

US 11020617	Konofagou et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Elisa E. Konofagou (New York, New York); Matthew Downs (New York, New York); Stephen Lee (New York, New York); Min Gon Kim (Fort Lee, New Jersey); Hermes Arytto Salles Kamimura (New York, New York)
ABSTRACT	Techniques for modulating peripheral nerves using focused ultrasound (FUS) are provided. Methods include locating a peripheral nerve in a subject using an imaging probe, providing a FUS having one or more ultrasound parameters to a location on the peripheral nerve, and modulating the peripheral nerve. The methods can further include eliciting and measuring a physiological response from the FUS modulation, generating tissue deformation in the vicinity of the FUS modulation, and imaging the nerve and the tissue deformation simultaneously with FUS modulation. Systems for use in the modulation of peripheral nerves are also provided.
FILED	Friday, February 01, 2019
APPL NO	16/265827
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/024 (20130101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/4836 (20130101) A61B 8/14 (20130101) A61B 8/42 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/0026 (20130101)
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11020730 — Halogen-containing metathesis catalysts and methods thereof

US 11020730	Hoveyda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	Amir H. Hoveyda (Lincoln, Massachusetts); Ming Joo Koh (Chestnut Hill, Massachusetts); Thach T. Nguyen (Newton, Massachusetts); Richard R. Schrock (Winchester, Massachusetts); Jakub Hyvl (Honolulu, Hawaii)
ABSTRACT	The present disclosure provides compounds, compositions, and methods for preparing alkenyl halides and/or haloalkyl-substituted olefins with Z-selectivity. The methods are particularly useful for preparing alkenyl fluorides such as CF₃-substituted olefins by means of cross-metathesis reactions using halogen-containing molybdenum and tungsten complexes.
FILED	Friday, July 14, 2017
APPL NO	16/317452
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1805 (20130101) B01J 31/2208 (20130101) Original (OR) Class B01J 2231/543 (20130101) B01J 2531/64 (20130101) Acyclic or Carbocyclic Compounds C07C 17/37 (20130101) C07C 41/18 (20130101) C07C 67/475 (20130101) C07C 209/68 (20130101) C07C 319/20 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/48 (20130101) C07D 211/18 (20130101) C07D 211/56 (20130101) C07D 307/79 (20130101) C07D 333/54 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/083 (20130101) C07F 11/00 (20130101) C07F 17/02 (20130101)
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11020736 — High definition microdroplet printer

US 11020736	Abate et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California)
ABSTRACT	Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided.
FILED	Tuesday, August 27, 2019
APPL NO	16/552982
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101)
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11021427 — Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids

US 11021427	Yu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	Jin-Quan Yu (San Diego, California); Pengxiang Shen (San Diego, California)
ABSTRACT	The invention includes procedures for stereoselective β-acylation of carboxylic acids having a β-carbon atom. For example, stereoselective acylation procedures include the following reactions: (I)
FILED	Wednesday, April 17, 2019
APPL NO	15/733763
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/232 (20130101) B01J 31/2213 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 51/353 (20130101) Original (OR) Class C07C 67/343 (20130101) C07C 201/12 (20130101) C07C 253/30 (20130101) Heterocyclic Compounds C07D 209/48 (20130101) C07D 209/49 (20130101) C07D 307/54 (20130101) C07D 333/24 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/4071 (20130101)
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11021435 — Serotonin receptor-targeting compounds and methods

US 11021435	Booth
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) National Institute of Mental Health (NIMH)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Raymond G. Booth (Arlington, Massachusetts)
ABSTRACT	This invention relates to, in part, compositions and methods that are useful for, inter alia, the treatment of various diseases, including those linked to binding at a serotonin receptor. The compositions include chiral tetrahydronaphthalen-2-amine derivatives. Accordingly, the present invention provides for compositions and methods that agonize or antagonize one or more serotonin receptors and which find Use in the treatment of various neuropsychiatric diseases or disorders including, without limitation, autism spectrum disorder (ASD) or associated symptoms.
FILED	Tuesday, May 19, 2015
APPL NO	15/311905
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Acyclic or Carbocyclic Compounds C07C 211/42 (20130101) Original (OR) Class C07C 215/64 (20130101) C07C 217/74 (20130101) C07C 2601/08 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 217/04 (20130101) C07D 307/52 (20130101)
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11021447 — Fluorescent halogen bonding arylethynyl scaffolds for anion recognition

US 11021447	Lohrman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Oregon (Eugene, Oregon); University of Montana (Missoula, Montana)
ASSIGNEE(S)	University of Oregon (Eugene, Oregon); University of Montana (Missoula, Montana)
INVENTOR(S)	Jessica Lohrman (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Michael M. Haley (Eugene, Oregon); Orion B. Berryman (Missoula, Montana); Asia M. Riel (Missoula, Montana); Daniel A. Decato (Missoula, Montana)
ABSTRACT	A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R¹⁰is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
FILED	Wednesday, May 01, 2019
APPL NO	16/401037
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 213/22 (20130101) C07D 213/90 (20130101) C07D 233/56 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101)
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11021450 — PSMA targeted fluorescent agents for image guided surgery

US 11021450	Pomper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Martin G. Pomper (Baltimore, Maryland); Ronnie C. Mease (Fairfax, Virginia); Ying Chen (Timonium, Maryland); Sangeeta Ray (Ellicott City, Maryland)
ABSTRACT	Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
FILED	Monday, March 16, 2020
APPL NO	16/820052
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0052 (20130101) A61K 51/044 (20130101) A61K 51/0421 (20130101) A61K 51/0446 (20130101) A61K 51/0453 (20130101) A61K 51/0472 (20130101) Heterocyclic Compounds C07D 209/12 (20130101) C07D 209/14 (20130101) C07D 209/24 (20130101) C07D 213/04 (20130101) C07D 249/04 (20130101) C07D 255/02 (20130101) C07D 257/02 (20130101) Original (OR) Class C07D 311/14 (20130101) C07D 311/20 (20130101) C07D 311/82 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) C07F 13/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 2800/342 (20130101)
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11021453 — Carbamate compounds and methods of making and using same

US 11021453	Cisar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Lundbeck La Jolla Research Center, Inc. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S)	LUNDBECK LA JOLLA RESEARCH CENTER, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	Justin S. Cisar (San Diego, California); Cheryl A. Grice (Encinitas, California); Todd K. Jones (Solana Beach, California); Micah J. Niphakis (San Diego, California); Jae Won Chang (San Diego, California); Kenneth M. Lum (San Diego, California); Benjamin F. Cravatt (San Diego, California)
ABSTRACT	This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for a method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
FILED	Tuesday, December 17, 2019
APPL NO	16/717813
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) Acyclic or Carbocyclic Compounds C07C 271/10 (20130101) C07C 271/12 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/09 (20130101) C07D 207/14 (20130101) C07D 213/38 (20130101) C07D 213/40 (20130101) C07D 213/55 (20130101) C07D 215/42 (20130101) C07D 215/46 (20130101) C07D 231/12 (20130101) C07D 231/16 (20130101) C07D 231/56 (20130101) C07D 241/04 (20130101) C07D 261/08 (20130101) C07D 263/32 (20130101) C07D 271/06 (20130101) C07D 295/26 (20130101) C07D 295/205 (20130101) Original (OR) Class C07D 307/79 (20130101) C07D 317/46 (20130101) C07D 317/58 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 405/14 (20130101) C07D 407/06 (20130101) C07D 413/06 (20130101) C07D 413/10 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101)
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11021469 — Indoline sulfonamide inhibitors of DapE and NDM-1 and use of the same

US 11021469	Becker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois); Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois); Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Daniel Paul Becker (Glenview, Illinois); Tahirah K. Heath (Chicago, Illinois); Cory Reidl (Franklin Grove, Illinois); Walter Fast (Austin, Texas)
ABSTRACT	Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.
FILED	Wednesday, July 17, 2019
APPL NO	16/514921
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/10 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) Original (OR) Class
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11021471 — Antibacterial compounds

US 11021471	Teng et al.
FUNDED BY	Department of Health and Human Services (HHS) Assistant Secretary for Preparedness and Response (ASPR)
APPLICANT(S)	FORGE THERAPEUTICS, INC. (San Diego, California)
ASSIGNEE(S)	FORGE THERAPEUTICS, INC. (San Diego, California)
INVENTOR(S)	Min Teng (San Diego, California); Baskar Nammalwar (San Diego, California); Konstantin Taganov (San Diego, California); Xiaoming Li (San Diego, California); David T. Puerta (San Diego, California)
ABSTRACT	Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
FILED	Wednesday, May 09, 2018
APPL NO	16/612308
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 309/40 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 407/04 (20130101) C07D 413/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 493/04 (20130101)
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11021488 — Hetero-substituted cyclic lactone analogues and uses thereof

US 11021488	Guzman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Office of the Director (NIHOD)
APPLICANT(S)	BioVentures, LLC (Little Rock, Arkansas); Cornell University (Ithaca, New York); New York Botanical Garden (Bronx, New York)
ASSIGNEE(S)	Board of Trustees of the University of Arkansas (Little Rock, Arkansas); BioVentures, LLC (Little Rock, Arkansas); Cornell University (Ithaca, New York); New York Botanical Garden (Bronx, New York)
INVENTOR(S)	Monica L. Guzman (Ithaca, New York); Cesar M. Compadre (Little Rock, Arkansas); Paola E. Ordonez (Little Rock, Arkansas); Mariano Martinez (Little Rock, Arkansas); Michael J. Balick (Bronx, New York); Darin E. Jones (Little Rock, Arkansas); Flavio G. Gaudio (Ithaca, New York)
ABSTRACT	The present disclosure provides SL and SL derivatives comprising a polar substituent adjacent to the lactone ring. Additionally, the present disclosure provides methods of using the SL and SL derivatives to inhibit the growth of leukemic cancer cells.
FILED	Friday, July 26, 2019
APPL NO	16/523687
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Heterocyclic Compounds C07D 307/93 (20130101) C07D 493/04 (20130101) C07D 493/08 (20130101) C07D 493/10 (20130101) Original (OR) Class C07D 493/18 (20130101)
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11021502 — Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA)

US 11021502	Eberwine et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Institute of Mental Health (NIMH)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	James Eberwine (Philadelphia, Pennsylvania); Ivan J. Dmochowski (Philadelphia, Pennsylvania); Sean B. Yeldell (Philadelphia, Pennsylvania); Julianne C. Griepenburg (Philadelphia, Pennsylvania); Teresa L. Rapp (Philadelphia, Pennsylvania); Jennifer M. Singh (Havertown, Pennsylvania); Jai-Yoon Sul (Cherry Hill, New Jersey); Jaehee Lee (Wynnewood, Pennsylvania)
ABSTRACT	Compositions and methods of capturing one or more nucleic acid molecules of a cell or subcellular compartment are described. In certain aspects, the compositions comprise a caged molecule comprising one or more photolinkers and an antisense oligonucleotide, which when uncaged hybridizes to a target nucleic acid molecule.
FILED	Tuesday, August 04, 2015
APPL NO	15/501073
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) B01J 2531/821 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/32 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2310/3233 (20130101) C12N 2310/3517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6823 (20130101) C12Q 1/6825 (20130101)
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11021506 — Thiosaccharide mucolytic agents

US 11021506	Oscarson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California); University College Dublin (Dublin, Ireland)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); University College Dublin (Dublin, Ireland)
INVENTOR(S)	Stefan Oscarson (Blackrock, Ireland); John Vincent Fahy (San Francisco, California); Shaopeng Yuan (San Francisco, California); Stephen Carrington (Roundwood, Ireland)
ABSTRACT	There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
FILED	Friday, November 22, 2019
APPL NO	16/692300
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 31/702 (20130101) A61K 31/7016 (20130101) A61K 31/7028 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 11/04 (20180101) A61P 11/06 (20180101) A61P 11/12 (20180101) A61P 43/00 (20180101) Heterocyclic Compounds C07D 309/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/04 (20130101) C07H 13/04 (20130101) C07H 15/04 (20130101) Original (OR) Class
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11021517 — Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic delivery

US 11021517	Nguyen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Quyen T. Nguyen (La Jolla, California); Mike Whitney (San Diego, California); Dina Hingorani (San Diego, California); Roger Y. Tsien (Eugene, Oregon); Stephen Adams (Poway, California)
ABSTRACT	The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
FILED	Monday, February 03, 2020
APPL NO	16/780782
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 41/0057 (20130101) A61K 47/64 (20170801) A61K 49/0056 (20130101) Peptides C07K 7/00 (20130101) C07K 7/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101)
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11021518 — Theta defensin analogs

US 11021518	Selsted et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Justin B. Schaal (Orange, California)
ASSIGNEE(S)	The University of Southern California (Los Angeles, California)
INVENTOR(S)	Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Justin B. Schaal (Orange, California)
ABSTRACT	Novel peptide analogs of a θ-defensin have been developed that provide a biphasic effect in treating infection and/or sepsis. These analogs are active at concentrations below those needed to provide a bactericidal or bacteriostatic effect, and function by initially recruiting effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response characteristic of sepsis and septic shock. These novel θ-defensin analogs are protective at concentrations where naturally occurring θ-defensins have no apparent effect, and include a core set of structural and sequence features not found in native θ-defensin.
FILED	Friday, June 26, 2020
APPL NO	16/914038
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 7/64 (20130101) Original (OR) Class
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11021533 — Human Zika virus antibodies and methods of use therefor

US 11021533	Crowe, Jr.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	James E. Crowe, Jr. (Nashville, Tennessee)
ABSTRACT	The present disclosure is directed to antibodies binding to and neutralizing Zika virus and methods for use thereof.
FILED	Wednesday, November 01, 2017
APPL NO	16/346709
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/18 (20130101) G01N 2333/185 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11021535 — Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use

US 11021535	Seder et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); SANARIA INC (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Sanaria Inc. (Rockville, Maryland)
INVENTOR(S)	Robert Seder (Chevy Chase, Maryland); Neville Kisalu (Bethesda, Maryland); Azza Idris (Bethesda, Maryland); Barbara Flynn (Bethesda, Maryland); Stephen Hoffman (Rockville, Maryland)
ABSTRACT	Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
FILED	Monday, February 12, 2018
APPL NO	16/485354
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/205 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101)
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11021539 — Drug delivery compositions and uses thereof

US 11021539	Goldberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Michael Solomon Goldberg (Brookline, Massachusetts); Chun Gwon Park (Seoul, South Korea)
ABSTRACT	Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.
FILED	Thursday, August 01, 2019
APPL NO	16/529189
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 31/444 (20130101) A61K 31/444 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 35/17 (20130101) A61K 38/19 (20130101) A61K 38/19 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 16/2896 (20130101) C07K 2317/75 (20130101)
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11021545 — Multimodal cancer therapy comprising chimeric viral/nonviral nanoparticles and anticancer agents

US 11021545	Kwon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Young Jik Kwon (Irvine, California); Margaret Lugin (Irvine, California)
ABSTRACT	The disclosure provides for a multimodal cancer therapy comprising chimeric viral/nonviral nanoparticles and anticancer agents and uses thereof to treat a subject with cancer or suspected of having a cancer.
FILED	Wednesday, July 31, 2019
APPL NO	16/528305
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) Peptides C07K 14/4746 (20130101) C07K 14/4747 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/3007 (20130101) Original (OR) Class C07K 16/3053 (20130101) C07K 16/3092 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101)
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11021687 — Production of differentiated enteroendocrine cells and insulin producing cells

US 11021687	Karp et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham And Women's Hospital, Inc. (Boston, Massachusetts); Massachusetts Institute Of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jeffrey Michael Karp (Brookline, Massachusetts); Robert Samuel Langer (Newton, Massachusetts); Xiaolei Yin (Quincy, Massachusetts)
ABSTRACT	A population of enteroendocrine cells (EEC) is obtained from a mammalian post-natal cell population, such as a population including post-natal stem cells, by treating the population with a plurality of small molecules that upregulate ChgA and promote differentiation of the cells to form the enteroendocrine cells. The upregulation of ChgA is such that the fraction of cells expressing CGA in the obtained cell population, as measured by a ChgA Immunostaining Assay, is at least about 1.5%. Small molecules that can be used to differentiate the post-natal cells into the enteroendocrine cells can include at least one of a Wnt activator, a Notch inhibitor, a Wnt inhibitor, a MEK/ERK inhibitor, a growth factor, a HDAC inhibitor, a Histone Methylation Inhibitor, a Tgf-β inhibitor, and a NeuroD1 activator. Also, the insulin expression of a population of mammalian cells is increased by treating the population with a plurality of small molecules that increase the insulin expression.
FILED	Friday, January 06, 2017
APPL NO	15/400877
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0613 (20130101) C12N 5/0678 (20130101) Original (OR) Class C12N 5/0679 (20130101) C12N 2500/38 (20130101) C12N 2500/62 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/42 (20130101) C12N 2501/065 (20130101) C12N 2501/71 (20130101) C12N 2501/72 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/335 (20130101) C12N 2501/395 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2502/23 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101)
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11021688 — Derivation of human skin organoids from pluripotent stem cells

US 11021688	Koehler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana)
ASSIGNEE(S)	INDIANA UNIVERSITY RESEARCH ANND TECHNOLOGY CORPORATION (Indianapolis, Indiana)
INVENTOR(S)	Karl R. Koehler (Indianapolis, Indiana); Jiyoon Lee (Indianapolis, Indiana)
ABSTRACT	Provided herein are methods for directing differentiation of human pluripotent stem cells into a three-dimensional multilayered skin composition comprising an epidermal layer, a dermal layer, and a plurality of cells capable of forming a functional hair follicle. Also provided herein are three-dimensional, multilayered engineered skin compositions and methods of using the same for drug screening, for screening compounds for effects on hair growth, and for other applications.
FILED	Friday, October 21, 2016
APPL NO	15/769139
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/36 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/60 (20130101) A61L 27/362 (20130101) A61L 27/3633 (20130101) A61L 27/3641 (20130101) A61L 27/3687 (20130101) A61L 27/3813 (20130101) A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 27/3891 (20130101) A61L 27/3895 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2300/604 (20130101) A61L 2430/34 (20130101) A61L 2430/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0627 (20130101) C12N 5/0629 (20130101) C12N 5/0656 (20130101) C12N 5/0698 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/999 (20130101) C12N 2502/092 (20130101) C12N 2502/094 (20130101) C12N 2502/1323 (20130101) C12N 2506/02 (20130101) C12N 2506/03 (20130101) C12N 2506/45 (20130101) C12N 2506/1346 (20130101) C12N 2513/00 (20130101) C12N 2533/76 (20130101) C12N 2533/90 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 2600/136 (20130101)
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11021703 — Methods and kit for characterizing the modified base status of a transcriptome

US 11021703	Jaffrey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Samie R. Jaffrey (New York, New York); Kate D. Meyer (New York, New York); Christopher E. Mason (New York, New York)
ABSTRACT	This invention relates to a method of characterizing the modified base status of a transcriptome, which involves contacting a transcriptome comprising one or more modified bases with an antibody specific to the modified bases under conditions effective to bind the antibody to the modified bases; isolating, from the transcriptome, a pool of RNA transcripts to which the antibody binds; and identifying isolated RNA transcripts that are present in a higher abundance in the isolated pool relative to the transcriptome, where each of the isolated RNA transcripts that are present in a higher abundance in the isolated pool together characterize the modified base status of the transcriptome. Also disclosed are a method of diagnosis or prognosis of a disease, a method of determining the effect of a treatment on modified base levels in RNA, and a kit for characterizing the modified base status of a transcriptome.
FILED	Monday, February 18, 2013
APPL NO	14/377680
ART UNIT	1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 2545/114 (20130101) C12Q 2563/149 (20130101) C12Q 2565/113 (20130101)
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11021706 — Antisense antibacterial compounds and methods

US 11021706	Geller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Oregon State University (Corvallis, Oregon); Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas); Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Bruce L. Geller (Corvallis, Oregon); David Greenberg (Coppell, Texas)
ABSTRACT	Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or genes associated with fatty acid biosynthesis, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.
FILED	Friday, September 01, 2017
APPL NO	15/693796
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/64 (20170801) A61K 47/6455 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2320/50 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101)
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11021709 — Lin28/let-7 crystal structures, purification protocols, and molecular probes suitable for screening assays and therapeutics

US 11021709	Sliz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Piotr Sliz (Canton, Massachusetts); Yunsun Nam (Dallas, Texas)
ABSTRACT	The invention provides compositions and methods for regulating microRNA (miRNA) biogenesis. The invention also relates to compositions and methods for treating or preventing cancer in a subject in need thereof.
FILED	Friday, May 29, 2020
APPL NO	16/887632
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 31/7115 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/645 (20170801) A61K 48/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/47 (20130101) C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101)
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11021712 — MiRNA mimics and uses thereof

US 11021712	Hou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Jianghui Hou (St. Louis, Missouri); Yong-feng Gong (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Jianghui Hou (St. Louis, Missouri); Yong-feng Gong (St. Louis, Missouri)
ABSTRACT	Among the various aspects of the present disclosure is the provision of miRNA mimics and uses thereof. An aspect of the present disclosure provides for compositions of miRNA mimic molecules and methods of treating metabolic disorders using miRNA mimic molecules.
FILED	Thursday, September 05, 2019
APPL NO	16/561602
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/321 (20130101) C12N 2310/351 (20130101) C12N 2310/3515 (20130101)
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11021737 — Compositions and methods for analyte detection

US 11021737	Church et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	George M. Church (Brookline, Massachusetts); Je-hyuk Lee (Allston, Massachusetts); Daniel Levner (Boston, Massachusetts); Michael Super (Lexington, Massachusetts)
ABSTRACT	Methods of making a three-dimensional matrix of nucleic acids within a cell is provided.
FILED	Wednesday, July 29, 2020
APPL NO	16/941585
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101)
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11021740 — Devices for CRISPR effector system based diagnostics

US 11021740	Abudayyeh et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Newton, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts)
ABSTRACT	The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.
FILED	Thursday, March 15, 2018
APPL NO	15/922837
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 7/52 (20130101) B01L 2300/0825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/6816 (20130101) C12Q 1/6823 (20130101) C12Q 1/6827 (20130101) C12Q 1/6832 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/558 (20130101)
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11021741 — Methods for attaching cellular constituents to a matrix

US 11021741	Wu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Chao-ting Wu (Brookline, Massachusetts); Son Nguyen (West Roxbury, Massachusetts)
ABSTRACT	The present invention relates to a method of covalently attaching a chromosome within a cell to a matrix including modifying a plurality of nucleotides within the chromosome to include a matrix attachment moiety wherein the chromosome contacts the matrix, and attaching the matrix attachment moiety of the plurality of nucleotides to the matrix, thereby attaching the chromosome to the matrix.
FILED	Wednesday, April 19, 2017
APPL NO	16/095456
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6841 (20130101) Original (OR) Class C12Q 2523/101 (20130101)
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11021750 — Biomarkers for predicting risk of acute ischemic stroke and methods of use thereof

US 11021750	Baird et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Research Foundation for State University of New York (Albany, New York)
ASSIGNEE(S)	THE RESEARCH FOUNDATION FOR STATE UNIVERSITY OF NEWYORK (Albany, New York)
INVENTOR(S)	Alison E. Baird (Brooklyn, New York); Mateusz Adamski (Kradow, Poland)
ABSTRACT	Biomarkers useful for the diagnosis and treatment of acute ischemic stroke are disclosed. Also provided is a quantitative assay method for accurately identifying transcript number in a biological sample.
FILED	Tuesday, October 14, 2014
APPL NO	15/028732
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101)
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11022529 — Sizable tunable enrichment platform for capturing nano particles in a fluid

US 11022529	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) United States Air Force (USAF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI) Department of Agriculture (USDA)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Siyang Zheng (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Yin-Ting Yeh (State College, Pennsylvania); Yi Tang (State College, Pennsylvania); Huaguang Lu (State College, Pennsylvania); Nestor Perea Lopez (State College, Pennsylvania); Yiqiu Xia (State College, Pennsylvania)
ABSTRACT	The invention provides enrichment platform devices for size-based capture of particles in solution. The enrichment platform device is useful for label-free capture of any particle. The invention relates to enrichment platform devices using nanowires and vertically aligned carbon nanotubes. The invention provides methods for making the enrichment platform devices. The invention provides methods for using the enrichment platform devices for filtering particles, capturing particles, concentrating particles, and releasing viable particles.
FILED	Friday, February 07, 2020
APPL NO	16/784507
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/12 (20130101) B01L 2300/041 (20130101) B01L 2300/0681 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) Original (OR) Class G01N 1/4077 (20130101) G01N 33/552 (20130101) G01N 33/54346 (20130101) G01N 33/56983 (20130101) G01N 2001/4088 (20130101) G01N 2333/11 (20130101)
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11022601 — Use of Eomesodermin to determine risk of allograft rejection

US 11022601	Ezzelarab et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	(Pittsburgh, Pennsylvania)
INVENTOR(S)	Mohamed B. Ezzelarab (Pittsburgh, Pennsylvania); Angus W. Thomson (Pittsburgh, Pennsylvania)
ABSTRACT	Pre-existing alloreactive memory T cells are a major barrier to the induction of allograft tolerance in organ transplant recipients. The use of Eomesodermin (Eomes) expression in memory T cells to determine the risk of allograft rejection in a subject is described. Also described is the use of Eomes expression in memory T cells of transplant recipients to modify immunosuppressive therapy.
FILED	Friday, January 22, 2016
APPL NO	15/545414
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class G01N 2333/4703 (20130101)
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11022602 — Antibiotic-based conjugates and methods of use thereof

US 11022602	Carlson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S)	Erin Elizabeth Carlson (Minneapolis, Minnesota); Shabnam Sharifzadeh (Minneapolis, Minnesota)
ABSTRACT	The invention provides a conjugate of formula I: R-L-Y I or a salt thereof, wherein R, L, and Y have any of the values described in the specification, as well as compositions comprising a conjugate of formula I. The conjugates are useful for labeling.
FILED	Friday, April 06, 2018
APPL NO	15/947302
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) A61K 47/12 (20130101) A61K 47/16 (20130101) A61K 47/22 (20130101) A61K 47/552 (20170801) A61K 49/0021 (20130101) A61K 49/0041 (20130101) A61K 49/0052 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 477/00 (20130101) C07D 501/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/532 (20130101) G01N 33/566 (20130101) G01N 33/5008 (20130101) Original (OR) Class
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11022605 — Multi-component in vitro system to deduce cell signaling pathways by electronic stimulation patterns

US 11022605	Hickman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	James Hickman (Orlando, Florida); Lee Kumanchik (Orlando, Florida); Navaneetha Santhanam (Orlando, Florida)
ABSTRACT	Disclosed herein are cell culture analog devices, systems and methods for applying stimuli to components containing different cell types and recording the cell responses before, during, and after a stimulus (for example, a drug, metabolite, toxin, or electrical stimulus) is introduced. Responses can be stored to a database and compared to previous results. By analyzing how each cell type responds to various stimulation parameters, for example, by using multivariate analyses, cell signaling pathway information can be determined or new pathways can be discovered. In some implementations, an individual component interfaces with a specific cell type. This facilitates readout of the cell response to the stimulation. Various components can also interface with each other, such that the behavior of one cell type can affect a cell type in another component. Once assembled, the system is plugged into readout electronics and a programmable electrical stimulator.
FILED	Wednesday, August 16, 2017
APPL NO	16/328417
ART UNIT	1799 — Organic Chemistry
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5014 (20130101) Original (OR) Class G01N 33/5029 (20130101)
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11022613 — Mass spectrometry imaging of glycans from tissue sections and improved analyte detection methods

US 11022613	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Hui Zhang (Ellicott City, Maryland); Xingde Li (Ellicott City, Maryland); Shadi Toghi Eshghi (Baltimore, Maryland)
ABSTRACT	The presently disclosed subject matter provides methods using mass spectrometry for direct profiling of N-linked glycans from a biological sample. In addition, the embodiments of the present invention also disclose novel methods, known as targeted analyte detection (TAD), for improving the detection limit of MALDI-MS. These methods take advantage of the carrier effect of the added standard analytes, which occurs due to the generic sigmoidal shape of the calibration curve. The functionality of TAD depends on the relative enhancement of sensitivity over the increase of the standard deviation at the analysis of target analytes with spiking in exogenous concentration. At certain ranges of exogenous concentration, the increment in the sensitivity overcomes the standard deviation, resulting in an improved LOD. Theoretically, exogenous concentrations approximately at 1 LODorig would generate the optimum LOD improvement. TAD is a cost-effective LOD improvement method, which is not limited to a certain group of analytes, or detection methods or instruments. It can be applied to enhance the detection of any analyte with different detection methods, provided that the analyte of interest can be extracted or is available in synthetic form.
FILED	Thursday, August 15, 2019
APPL NO	16/541581
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class G01N 33/6851 (20130101) G01N 2400/12 (20130101) G01N 2570/00 (20130101)
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11022615 — Regulatory T-cells, method for their isolation and uses

US 11022615	Brusko et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Todd M. Brusko (Gainesville, Florida); Christopher Fuhrman (Cambridge, Massachusetts); Howard R. Seay (Gainesville, Florida)
ABSTRACT	The invention pertains to methods of isolating a Treg from a subject, the method comprising the steps of analyzing a sample of cells obtained from the subject to determine the level of expression of polypeptides and/or polynucleotides corresponding to proteins CD 127, CD4, CD25, and CD226 and isolating, as the Treg, a cell which expresses CD4 and CD25, expresses low levels of CD 127 or does not express CD 127, and expresses low levels of CD226 or does not express CD226. The Treg isolated from a subject can be proliferated in vitro. Accordingly, the invention also provides compositions comprising Treg isolated/proliferated according to the methods of the invention and pharmaceutically acceptable carrier and/or excipient. The pharmaceutical compositions can be used to treat and/or prevent inflammation mediated disease, for example, autoimmune diseases, such as, systemic lupus erythmatosus, rheumatoid arthritis, Multiple Sclerosis, type 1 diabetes, or inflammatory bowel disease.
FILED	Wednesday, May 04, 2016
APPL NO	15/571823
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) C12N 2501/2312 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 33/6854 (20130101) Original (OR) Class G01N 2015/149 (20130101) G01N 2333/70503 (20130101) G01N 2333/70514 (20130101)
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11022618 — Antibody based reagents that specifically recognize neurodegenerative disease related forms of the protein TDP-43

US 11022618	Sierks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Michael Sierks (Ft. McDowell, Arizona); Stephanie Williams (Phoenix, Arizona); Lalitha Venkataraman (Tempe, Arizona)
ABSTRACT	The invention relates to antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with frontotemporal dementia (FTD), but not TDP-43 associated with amyotrophic lateral sclerosis (ALS) or TDP-43 associated with healthy human brain tissue, and antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with ALS, but not TDP-43 associated FTD or TDP-43 associated with healthy human brain tissue.
FILED	Wednesday, December 05, 2018
APPL NO	16/211006
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/18 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/285 (20130101) G01N 2800/2814 (20130101)
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11022665 — Method for echo planar time-resolved magnetic resonance imaging

US 11022665	Setsompop et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Kawin Setsompop (Charlestown, Massachusetts); Lawrence L. Wald (Cambridge, Massachusetts); Fuyixue Wang (Cambridge, Massachusetts)
ABSTRACT	Systems and methods for magnetic resonance imaging (“MRI”) that address the geometric distortions and blurring common to conventional echo planar imaging (“EPI”) sequences, and that provide new temporal signal evolution information across the EPI readout, are described. Echo planar time-resolved imaging (“EPTI”) schemes are described to implement an accelerated sampling of a hybrid space spanned by the phase encoding dimension and the temporal dimension. In general, each EPTI shot covers a segment of this hybrid space using a zigzag trajectory with an interleaved acceleration in the phase-encoding direction. The hybrid space may be undersampled and a tilted reconstruction kernel used to synthesize additional data samples.
FILED	Monday, June 03, 2019
APPL NO	16/430349
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/482 (20130101) Original (OR) Class G01R 33/5602 (20130101) G01R 33/5616 (20130101) G01R 33/56563 (20130101)
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11023820 — System and methods for trajectory pattern recognition

US 11023820	Fang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S)	Hua Fang (Shrewsbury, Massachusetts)
ABSTRACT	A multiple imputation (MI) based fuzzy clustering with visualization-aided MI validation that improves the accuracy and the stability of identified patterns, generally the structure of HD data with missing values.
FILED	Friday, February 06, 2015
APPL NO	15/116570
ART UNIT	2126 — AI & Simulation/Modeling
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6218 (20130101) G06K 9/6253 (20130101) Computer Systems Based on Specific Computational Models G06N 7/02 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/20 (20130101) G06T 2207/30241 (20130101)
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11024018 — Imaging methods and computer-readable media

US 11024018	Sarkar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Susanta Kumar Sarkar (Rockville, Maryland); Ambika Bumb (Greer, South Carolina); Keir Cajal Neuman (Bethesda, Maryland)
ABSTRACT	One aspect of the invention provides an imaging method including: (a) acquiring a first fluorescent image of an object of interest impregnated with fluorescent nanodiamonds; (b) applying a magnetic field to the fluorescent nanodiamonds in order to decrease fluorescence of the fluorescent nanodiamonds; (c) acquiring a second fluorescent linage of the object of interest; and (d) subtracting the second fluorescent linage from the first fluorescent image to produce a resulting image. Another aspect of the invention provides an imaging method including: (a) applying a time-varying magnetic field to an object of interest impregnated with fluorescent nanodiamonds to modulate the fluorescence of the fluorescent nanodiamonds; (b) acquiring a plurality of fluorescent images of the object of interest; and (c) for each corresponding pixel in the plurality of fluorescent images, calculating a fluorescence intensity using a lock-in technique.
FILED	Monday, August 22, 2016
APPL NO	15/243765
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6439 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 5/003 (20130101) G06T 5/50 (20130101) Original (OR) Class G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/20182 (20130101) G06T 2207/20216 (20130101) G06T 2207/20224 (20130101) G06T 2207/30024 (20130101)
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11024024 — Systems and methods for analyzing perfusion-weighted medical imaging using deep neural networks

US 11024024	Arnold et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Corey Arnold (Oakland, California); King Chung Ho (Oakland, California); Fabien Scalzo (Oakland, California)
ABSTRACT	Systems and methods for analyzing perfusion-weighted medical imaging using deep neural networks are provided. In some aspects, a method includes receiving perfusion-weighted imaging data acquired from a subject using a magnetic resonance (“MR”) imaging system and modeling at least one voxel associated with the perfusion-weighted imaging data using a four-dimensional (“4D”) convolutional neural network. The method also includes extracting spatio-temporal features for each modeled voxel and estimating at least one perfusion parameter for each modeled voxel based on the extracted spatio-temporal features. The method further includes generating a report using the at least one perfusion parameter indicating perfusion in the subject.
FILED	Thursday, December 15, 2016
APPL NO	16/062159
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0263 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2209/05 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 5/046 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2200/04 (20130101) G06T 2207/10096 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101)
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11024025 — Automatic quantification of cardiac MRI for hypertrophic cardiomyopathy

US 11024025	Meyer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Craig H. Meyer (Charlottesville, Virginia); Anudeep Konda (Los Angeles, California); Christopher M. Kramer (Charlottesville, Virginia); Xue Feng (Charlottesville, Virginia)
ABSTRACT	In one aspect the disclosed technology relates to embodiments of a method which, includes acquiring magnetic resonance imaging data, for a plurality of images, of the heart of a subject. The method also includes segmenting, using cascaded convolutional neural networks (CNN), respective portions of the images corresponding to respective epicardium layers and endocardium layers for a left ventricle (LV) and a right ventricle (RV) of the heart. The segmenting is used for extracting biomarker data from segmented portions of the images and, in one embodiment, assessing hypertrophic cardiomyopathy from the biomarker data. The method further includes segmenting processes for T1 MRI data and LGE MRI data.
FILED	Thursday, March 07, 2019
APPL NO	16/295939
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/029 (20130101) A61B 5/0263 (20130101) A61B 5/1071 (20130101) A61B 5/1075 (20130101) A61B 5/7267 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6228 (20130101) G06K 2209/051 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/13 (20170101) G06T 7/62 (20170101) G06T 7/70 (20170101) G06T 2207/10088 (20130101) G06T 2207/20084 (20130101) G06T 2207/30048 (20130101)
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11024096 — 3D-perceptually accurate manual alignment of virtual content with the real world with an augmented reality device

US 11024096	Leuze et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Christoph Leuze (Palo Alto, California); Supriya Sathyanarayana (Milpitas, California); Jennifer McNab (Stanford, California)
ABSTRACT	3D alignment of a virtual model and corresponding real-world object is provided. A user places virtual tags on the real-world object as viewed through an augmented reality device. By placing these tags at the positions where he perceives certain real-world landmark locations, this allows for correction of misalignments between virtual content on the AR display and the real world. In particular, the virtual model include virtual landmarks that correspond to the real-world landmarks. Thus aligning the virtual landmarks of the virtual model to the virtual tags provides accurate alignment of the virtual model to the corresponding real-world object.
FILED	Wednesday, April 29, 2020
APPL NO	16/861220
ART UNIT	2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/344 (20170101) G06T 19/006 (20130101) Original (OR) Class G06T 2207/30201 (20130101) G06T 2207/30204 (20130101) G06T 2215/16 (20130101) G06T 2219/004 (20130101)
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11024429 — Method, system and computer readable medium for adaptive and advisory control of diabetes

US 11024429	Patek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Science Foundation (NSF)
APPLICANT(S)	Stephen D. Patek (Charlottesville, Virginia); Boris P. Kovatchev (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	Stephen D. Patek (Charlottesville, Virginia); Boris P. Kovatchev (Charlottesville, Virginia)
ABSTRACT	An Adaptive Advisory Control (AA Control) interactive process involving algorithm-based assessment and communication of physiologic and behavioral parameters and patterns assists patients with diabetes with the optimization of their glycemic control. The method and system may uses all available sources of information about the patient; (i) EO Data (e.g. self-monitoring of blood glucose (SMBG) and CMG), (ii) Insulin Data (e.g. insulin pump log files or patient treatment records), and (iii) Patient Self Reporting Data (e.g. self treatment behaviors, meals, and exercise) to: retroactively assess the risk of hypoglycemia, retroactively assess risk-based reduction of insulin delivery, and then report to the patient how a risk-based insulin reduction system would have acted consistently to prevent hypoglycemia.
FILED	Sunday, August 26, 2012
APPL NO	14/241383
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0022 (20130101) A61B 5/486 (20130101) A61B 5/743 (20130101) A61B 5/1118 (20130101) A61B 5/4812 (20130101) A61B 5/4839 (20130101) A61B 5/4848 (20130101) A61B 5/4857 (20130101) A61B 5/4866 (20130101) A61B 5/7225 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) A61B 5/7282 (20130101) A61B 5/7475 (20130101) A61B 5/14532 (20130101) A61B 2505/07 (20130101) A61B 2560/0295 (20130101) A61B 2560/0475 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 5/16886 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 20/30 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) Original (OR) Class
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11025574 — RNA targeting methods and compositions

US 11025574	Hsu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) Office of the Director (NIHOD)
APPLICANT(S)	Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S)	Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S)	Patrick D. Hsu (San Diego, California); Silvana Konermann (Menlo Park, California)
ABSTRACT	Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
FILED	Wednesday, June 03, 2020
APPL NO	16/891574
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/8201 (20130101) C12N 15/8213 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/08 (20130101) H04L 9/30 (20130101) H04L 45/745 (20130101) H04L 51/08 (20130101) H04L 51/12 (20130101) Original (OR) Class H04L 51/14 (20130101) H04L 51/18 (20130101)
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Department of Defense (DOD)

11020279 — Wound stasis dressing for large surface wounds

US 11020279	Barofsky
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	RevMedx, Inc. (Wilsonville, Oregon)
ASSIGNEE(S)	RevMedx, Inc. (Wilsonville, Oregon)
INVENTOR(S)	Andrew Barofsky (Lake Oswego, Oregon)
ABSTRACT	Embodiments herein provide hemostatic compositions comprising a plurality of liquid-expandable articles arranged on a backing material. In general, embodiments include methods for treating hemorrhagic injuries. More specifically, there is provided a method to effect rapid hemostatic response and control hemorrhage by introducing a hemostatic composition into a bleeding wound cavity. An embodiment also provides a method of preparing or manufacturing such a hemostatic composition.
FILED	Friday, October 27, 2017
APPL NO	15/796663
ART UNIT	1699 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00051 (20130101) A61F 13/0233 (20130101) A61F 13/0243 (20130101) Original (OR) Class A61F 2013/00463 (20130101) A61F 2013/00468 (20130101)
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11020352 — Systems and methods for the fabrication of tablets, including pharmaceutical tablets

US 11020352	Myerson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Allan S. Myerson (Cambridge, Massachusetts); Mohammad A. Azad (Greensboro, North Carolina); Gregory J. Hammersmith (Windsor, Connecticut); David Brancazio (Cambridge, Massachusetts); Juan Guillermo Osorio Caicedo (Elizabeth, New Jersey)
ABSTRACT	Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
FILED	Tuesday, May 26, 2020
APPL NO	16/883909
ART UNIT	1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 3/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/2009 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2095 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/5513 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/1061 (20130101) B01F 13/1063 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/34 (20130101) Presses in General B30B 11/08 (20130101) B30B 11/027 (20130101) B30B 15/302 (20130101)
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11020404 — Use of CDK9 and BRD4 inhibitors to inhibit inflammation

US 11020404	Haudenschild et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents Of The University Of California, Davis (Oakland, California)
INVENTOR(S)	Dominik Haudenschild (Davis, California); Jasper Yik (Elk Grove, California)
ABSTRACT	Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit and/or prevent cartilage degradation and systemic traumatic inflammation. A combination of CDK9 inhibitors and BRD4 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. A combination of CDK9 inhibitors and BRD4 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED	Thursday, May 23, 2019
APPL NO	16/421218
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 31/445 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/5513 (20130101) Original (OR) Class A61K 31/5513 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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11020509 — Microfluidic extrusion

US 11020509	Francis et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Embody, Inc. (Norfolk, Virginia)
ASSIGNEE(S)	Embody, Inc. (Norfolk, Virginia)
INVENTOR(S)	Michael P. Francis (Norfolk, Virginia); Stella Petrova (Blacksburg, Virginia); Nicholas Thayer (Morrisville, North Carolina)
ABSTRACT	A biopolymer fiber containing collagen. The biopolymer fiber has excellent ultimate tensile strength, modulus of elasticity, and strain at break comparable to native human tendons and ligaments. The fiber may substantially circular, ovoid, square, rectangular, ribbon-like, triangular, or irregularly shaped. The fiber exhibits an ordered, longitudinally-oriented structure, and the fiber allows infiltration of cellular growth. Implantable biopolymer scaffolds and sutures containing the fibers are provided as well as microfluidic and extrusion methods for producing the biopolymer fibers.
FILED	Friday, January 31, 2020
APPL NO	16/779196
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/14 (20130101) A61L 17/105 (20130101) A61L 27/24 (20130101) Original (OR) Class A61L 27/386 (20130101) A61L 27/3804 (20130101) A61L 2430/10 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/02 (20130101) D01D 5/06 (20130101) D01D 5/38 (20130101) D01D 7/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101)
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11020521 — Hemocompatibility modifiers for cross-linked polymeric material

US 11020521	Golobish et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	CytoSorbents Corporation (Monmouth Junction, New Jersey)
ASSIGNEE(S)	CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey)
INVENTOR(S)	Thomas D. Golobish (Princeton, New Jersey); Vincent J. Capponi (Lawrenceville, New Jersey); David R. Clay (West Orange, New Jersey)
ABSTRACT	The invention concerns methods of removing undesirable molecules from the blood or physiologic fluid; said method comprising contacting said blood or physiologic fluid with a sorbent, said sorbent comprising a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of ligands attached to the surface of said cross-linked polymeric material, comprising (i) zwitterionic moieties, (ii) oligo(ethylene glycol) moieties or (iii) mixtures thereof; said contacting comprising said sorbent sorbing a plurality of said undesirable molecules when said sorbent is administered within a patient's body.
FILED	Friday, April 17, 2020
APPL NO	16/851305
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/02 (20130101) A01N 1/0215 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/34 (20130101) A61M 1/36 (20130101) A61M 1/0272 (20130101) A61M 1/3679 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/261 (20130101) B01J 20/267 (20130101) B01J 20/3208 (20130101) B01J 20/3246 (20130101) B01J 20/3248 (20130101) B01J 20/3251 (20130101) B01J 20/3272 (20130101) B01J 20/3282 (20130101) B01J 20/3285 (20130101) B01J 20/28069 (20130101) B01J 20/28078 (20130101) B01J 20/28092 (20130101) B01J 2220/62 (20130101)
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11020590 — Targeted remote electrostimulation by interference of bipolar nanosecond pulses

US 11020590	Pakhomov et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Old Dominion University Research Foundation (Norfolk, Virginia)
ASSIGNEE(S)	OLD DOMINION UNIVERSITY RESEARCH FOUNDATION (Norfolk, Virginia)
INVENTOR(S)	Andrei G. Pakhomov (Norfolk, Virginia); Olga N. Pakhomova (Norfolk, Virginia); Shu Xiao (Norfolk, Virginia)
ABSTRACT	Provided herein are methods of generating a biologically effective unipolar nanosecond electric pulse by superposing two biologically ineffective bipolar nanosecond electric pulses and related aspects, such as electroporation and/or therapeutic applications of these methods to non-invasively target electrostimulation (ES) selectively to deep tissues and organs.
FILED	Thursday, August 16, 2018
APPL NO	16/104089
ART UNIT	3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36 (20130101) A61N 1/323 (20130101) Original (OR) Class A61N 1/327 (20130101) A61N 1/0412 (20130101) A61N 1/0476 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101)
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11020617 — Methods and systems for peripheral nerve modulation using non ablative focused ultrasound with electromyography (EMG) monitoring

US 11020617	Konofagou et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Elisa E. Konofagou (New York, New York); Matthew Downs (New York, New York); Stephen Lee (New York, New York); Min Gon Kim (Fort Lee, New Jersey); Hermes Arytto Salles Kamimura (New York, New York)
ABSTRACT	Techniques for modulating peripheral nerves using focused ultrasound (FUS) are provided. Methods include locating a peripheral nerve in a subject using an imaging probe, providing a FUS having one or more ultrasound parameters to a location on the peripheral nerve, and modulating the peripheral nerve. The methods can further include eliciting and measuring a physiological response from the FUS modulation, generating tissue deformation in the vicinity of the FUS modulation, and imaging the nerve and the tissue deformation simultaneously with FUS modulation. Systems for use in the modulation of peripheral nerves are also provided.
FILED	Friday, February 01, 2019
APPL NO	16/265827
ART UNIT	3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/024 (20130101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/4836 (20130101) A61B 8/14 (20130101) A61B 8/42 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/0026 (20130101)
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11020736 — High definition microdroplet printer

US 11020736	Abate et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California)
ABSTRACT	Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided.
FILED	Tuesday, August 27, 2019
APPL NO	16/552982
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101)
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11021497 — Compositions and methods for synthesis of phosphorylated molecules

US 11021497	Chaput et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	John Chaput (Irvine, California); Jen-Yu Liao (Irvine, California); Saikat Bala (Irvine, California)
ABSTRACT	The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.
FILED	Thursday, April 04, 2019
APPL NO	16/374795
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/138 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/091 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101)
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11021516 — Self-assembling peptide polymer

US 11021516	Ulijn et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) U.S. Air Force Department of Energy (DOE) UChicago Argonne, LLC (UCHICAGO) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Rein V. Ulijn (New York, New York); Ayala Lampel (Bronx, New York); Tell Tuttle (Glasgow, United Kingdom); Gary Scott (Glasgow, United Kingdom); Scott McPhee (New York, New York); Christopher Bettinger (Pittsburgh, Pennsylvania)
ABSTRACT	A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.
FILED	Monday, September 11, 2017
APPL NO	16/332231
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 5/0819 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101)
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11021521 — Pore-modified gram-negative bacteria and uses thereof

US 11021521	Zgurskaya et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	THE BOARD OR REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma)
INVENTOR(S)	Helen Zgurskaya (Norman, Oklahoma); Jon W. Weeks (Laurel, Maryland)
ABSTRACT	Mutants of Gram-negative bacteria having outer membranes comprising modified OrbA nanopores absent an N-terminal plug domain are disclosed. The modified OrbA nanopores confer the outer membrane of the bacteria with enhanced permeability. The mutants of Gram-negative bacteria optionally comprise efflux-deficient efflux pumps. The mutants may be used, for example, in a screening method for identifying a compound having an anti-bacterial activity.
FILED	Tuesday, September 18, 2018
APPL NO	16/134696
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/21 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 14/212 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101)
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11021524 — Proteins from anaerobic fungi and uses thereof

US 11021524	O'Malley et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) United States Army (USA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michelle O'Malley (Santa Barbara, California); Kevin Solomon (Lafayette, Indiana); Charles Haitjema (San Jose, California)
ABSTRACT	Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
FILED	Wednesday, June 10, 2020
APPL NO	16/898421
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/37 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/0006 (20130101) C12N 9/24 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 21/02 (20130101) C12P 39/00 (20130101)
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11021529 — Antimicrobial constructs and uses thereof

US 11021529	Bhatia et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Sangeeta N. Bhatia (Lexington, Massachusetts); Ester Jihae Kwon (Cambridge, Massachusetts); Leslie W. Chan (Boston, Massachusetts)
ABSTRACT	Disclosed herein are antimicrobial constructs comprising a membrane interacting peptide and an antimicrobial agent. Also disclosed are methods for making and using the constructs.
FILED	Thursday, March 01, 2018
APPL NO	15/909006
ART UNIT	1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 47/644 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 7/06 (20130101) C07K 14/79 (20130101) Original (OR) Class C07K 14/4723 (20130101)
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11021661 — Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy

US 11021661	Strohm et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE) Battelle Memorial Institute (BATTELLE)
APPLICANT(S)	James J. Strohm (West Richland, Washington); John C. Linehan (Richland, Washington); Benjamin Q. Roberts (Richland, Washington); Douglas L. McMakin (Richland, Washington); David M. Sheen (Richland, Washington); Jeffrey W. Griffin (Kennewick, Washington); James A. Franz (Kennewick, Washington); Charlene Franz (Kennewick, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	James J. Strohm (West Richland, Washington); John C. Linehan (Richland, Washington); Benjamin Q. Roberts (Richland, Washington); Douglas L. McMakin (Richland, Washington); David M. Sheen (Richland, Washington); Jeffrey W. Griffin (Kennewick, Washington); James A. Franz (Kennewick, Washington)
ABSTRACT	Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.
FILED	Tuesday, February 21, 2012
APPL NO	13/401216
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/0093 (20130101) B01J 19/126 (20130101) B01J 2219/0086 (20130101) B01J 2219/00792 (20130101) B01J 2219/00822 (20130101) B01J 2219/00826 (20130101) B01J 2219/00835 (20130101) B01J 2219/0894 (20130101) B01J 2219/00941 (20130101) B01J 2219/1215 (20130101) B01J 2219/1227 (20130101) B01J 2219/1239 (20130101) B01J 2219/1245 (20130101) B01J 2219/1269 (20130101) B01J 2219/1272 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/00 (20130101) C10G 1/02 (20130101) C10G 1/08 (20130101) C10G 9/24 (20130101) C10G 15/08 (20130101) C10G 32/02 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 2001/4622 (20130101)
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11021730 — In vitro glycosylation of proteins and enzymes

US 11021730	Petillo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Design-Zyme LLC (Lawrence, Kansas)
ASSIGNEE(S)
INVENTOR(S)	Peter Albert Petillo (Lawrence, Kansas); Dwight O'Dell Deay, III (Lawrence, Kansas); Michael Gregory Branden (Lawrence, Kansas)
ABSTRACT	The present invention is broadly concerned with new in vitro glycosylation methods that provide rational approaches for producing glycosylated proteins, and the use of glycosylated proteins. In more detail, the present invention comprises methods of glycosylating a starting protein having an amino sidechain with a nucleophilic moiety, comprising the step of reacting the protein with a carbohydrate having an oxazoline moiety on the reducing end thereof, to covalently bond the amino sidechain of the starting protein with the oxazoline moiety, wherein the glycosylated protein substantially retains the structure and function of the starting protein. Target proteins include oxidase, oxidoreductase and dehydrogenase enzymes. The glycosylated proteins advantageously have molecular weights of at least about 7500 Daltons. In a further embodiment, the present invention concerns the use of glycosylated proteins, fabricated by the methods disclosed herein, in the assembly of amperometric biosensors.
FILED	Wednesday, December 19, 2018
APPL NO	16/224795
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 1/006 (20130101) C07K 1/1077 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0006 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class
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11021740 — Devices for CRISPR effector system based diagnostics

US 11021740	Abudayyeh et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Newton, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts)
ABSTRACT	The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.
FILED	Thursday, March 15, 2018
APPL NO	15/922837
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 7/52 (20130101) B01L 2300/0825 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/6816 (20130101) C12Q 1/6823 (20130101) C12Q 1/6827 (20130101) C12Q 1/6832 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/558 (20130101)
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11021958 — Split vernier ring for turbine rotor stack assembly

US 11021958	Juh et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) United States Army (USA)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Christopher M. Juh (Hobe Sound, Florida); Scott D. Virkler (Ellington, Connecticut)
ABSTRACT	A power turbine rotor assembly including a rotor shaft. The assembly also includes a rotor stack surrounding the rotor shaft. The assembly further includes a nut axially retaining the rotor stack. The assembly yet further includes a Vernier ring engaged with the nut and the rotor shaft, the Vernier ring having an inner ring, a plurality of inner tabs extending radially inward from the inner ring, and a plurality of outer tabs extending radially outward from the inner ring, the Vernier ring formed of at least two ring segments.
FILED	Wednesday, October 31, 2018
APPL NO	16/176894
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/025 (20130101) Original (OR) Class F01D 5/026 (20130101) F01D 5/066 (20130101)
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11021967 — Turbine engine component with a core tie hole

US 11021967	Gallier et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Kirk D. Gallier (Cincinnati, Ohio); Cedric Carlton Lowe (Cincinnati, Ohio)
ABSTRACT	An apparatus and method of forming an engine component having an outer wall forming an interior. The interior can be separated into two or more flow paths or flow channels. The two flow paths can be formed by casting having one or more core ties connecting the flow paths during casting. One or more core tie holes can be formed remnant of the core ties during casting in order to fluidly couple the two or more flow paths or flow channels.
FILED	Monday, April 03, 2017
APPL NO	15/477335
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Foundry Moulding B22C 9/10 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 9/04 (20130101) F01D 25/12 (20130101) F01D 25/32 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2230/211 (20130101) F05D 2240/304 (20130101) F05D 2240/307 (20130101) F05D 2250/141 (20130101) F05D 2260/202 (20130101)
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11022145 — Bushing arranged between a body and a shaft, and connected to the shaft

US 11022145	Maliniak et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) United States Navy (USN)
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	David Maliniak (Guilford, Connecticut); Nathan F. Champion (Enfield, Connecticut); Kenneth A. Frisk (West Hartford, Connecticut)
ABSTRACT	A variable area vane arrangement includes a stator vane, a bushing and a vane platform with an aperture. The stator vane rotates about an axis, and includes a shaft that extends along the axis into the aperture. The bushing is connected to the shaft, and is arranged within the aperture between the vane platform and the shaft.
FILED	Monday, August 20, 2018
APPL NO	16/105336
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Non-positive-displacement Pumps F04D 29/563 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/14 (20130101) F05D 2250/73 (20130101)
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11022308 — Double wall combustors with strain isolated inserts

US 11022308	Rudrapatna et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) United States Army (USA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina)
INVENTOR(S)	Nagaraja S. Rudrapatna (Chandler, Arizona); Ian Critchley (Prescott, Arizona); Jeffrey Spencer (Tempe, Arizona); Philip Smalley (Tempe, Arizona)
ABSTRACT	A combustor for a turbine engine includes a first liner and a second liner forming a combustion chamber with the first liner. The combustion chamber is configured to receive an air-fuel mixture for combustion therein. The first liner is a first double wall liner with a first wall forming a portion of the combustion chamber and a second wall extending around at least a portion of the first wall to form a liner cavity with the first wall. The first wall defines a first wall orifice and the second wall defines a second wall orifice. The combustor further includes a first insert mounted on the second wall within the second wall orifice and extending through the first wall orifice. The first insert is configured to direct a first air jet through the second wall, through the first wall, and into the combustion chamber.
FILED	Thursday, May 31, 2018
APPL NO	15/993986
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) Original (OR) Class F23R 3/50 (20130101) F23R 2900/00017 (20130101) F23R 2900/03041 (20130101)
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11022318 — Apparatus and method for operating a gas-fired burner on liquid fuels

US 11022318	Prada Bernal et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Precision Combustion, Inc. (North Haven, Connecticut)
ASSIGNEE(S)	PRECISION COMBUSTION, INC. (North Haven, Connecticut)
INVENTOR(S)	Julian David Prada Bernal (Middletown, Connecticut); Francesco Macri (Farmington, Connecticut)
ABSTRACT	A gas-fired burner adapted for use on a liquid fuel. A method for essentially smokeless start-up and steady state operation of a gas-fired burner on a liquid fuel. The apparatus integrates a catalytic liquid fuel reformer with a flame burner designed for operation on a gaseous fuel of high Wobbe Index, e.g., natural gas. The method involves reacting a mixture of a liquid fuel and oxidant in a catalytic reformer to obtain a gaseous reformate having a low Wobbe Index; and thereafter combusting the gaseous reformate, optionally augmented with liquid co-fuel and oxidant, in the gas-fired burner under diffusion flame conditions. The invention allows commercial gas-fired appliances to be operated on a liquid fuel, thereby offering advantages in logistics and camp operations.
FILED	Wednesday, July 31, 2019
APPL NO	16/527198
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Burners F23D 5/10 (20130101) F23D 5/126 (20130101) F23D 2204/10 (20130101) Feeding Fuel to Combustion Apparatus F23K 5/22 (20130101) Domestic Stoves or Ranges; Details of Domestic Stoves or Ranges, of General Application F24C 5/18 (20130101) Original (OR) Class
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11022378 — Advanced cooling system using throttled internal cooling passage flow for a window assembly, and methods of fabrication and use thereof

US 11022378	Tucker et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Mainstream Engineering Corporation (Rockledge, Florida)
ASSIGNEE(S)	Mainstream Engineering Corporation (Rockledge, Florida)
INVENTOR(S)	Brian P. Tucker (Orlando, Florida); Joshua D. Sole (Rockledge, Florida); Justin J. Hill (Merritt Island, Florida); Robert P. Scaringe (Rockledge, Florida)
ABSTRACT	A window assembly heat transfer system is disclosed in which a window member has a selected transparency to monitored or sensed light wavelengths. One or more passages are provided in the window member for flowing a single-phase or two-phase heat transfer fluid, the passages being optically non-transparent to the monitored or sensed light wavelengths. A mechanism allows either evaporation or condensation of the fluid and/or balancing of a flow of the fluid within the passages. In one embodiment, the window assembly can be made by producing passages in a top surface of a first single plate, optionally producing passages in a bottom surface of a second single plate and bonding the top surface of the first plate to a bottom surface of a second single plate to form the window member with the passage or passages. In another embodiment, the window assembly can be made by providing a core around which the window member material is grown and thereafter removing the core to produce the passage or passages.
FILED	Monday, January 20, 2020
APPL NO	16/747038
ART UNIT	2884 — Optics
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/56 (20130101) C23C 16/305 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 29/48 (20130101) C30B 33/08 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Original (OR) Class
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11022391 — Cartridge extraction with dummy extractor for a cased telescoped ammunition firearm

US 11022391	Shipley et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Textron Systems Corporation (Hunt Valley, Maryland)
ASSIGNEE(S)	Textron Systems Corporation (Hunt Valley, Maryland)
INVENTOR(S)	Paul Andrew Shipley (Millers, Maryland); Cameron Mehdi Brand (Towson, Maryland); Kevin Michael Ayotte (Baltimore, Maryland); Joshua Stephen Ruck (Baltimore, Maryland); Benjamin Tyler Cole (Baltimore, Maryland); William Henry Engel, IV (Cockeysville, Maryland)
ABSTRACT	A firearm for firing cased telescoped (CT) ammunition cartridges that includes a split chamber configured to fully support a CT cartridge when it is fired, and that includes i) a dynamic rear chamber portion defining a pocket in a face of a bolt, and ii) a static front chamber portion that is integral to the barrel and separate from the bolt. A cartridge extraction mechanism engages the CT cartridge prior to the CT cartridge being fired, and holds the CT cartridge in the pocket in the bolt face as the bolt moves rearward to pull the CT cartridge out of the static front chamber portion and into an ejection position. An ejector is operable to eject the CT cartridge from the pocket in the face of the bolt when the CT cartridge reaches the ejection position.
FILED	Thursday, March 05, 2020
APPL NO	16/809683
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 3/26 (20130101) F41A 15/14 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/045 (20130101)
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11022446 — Method and apparatus for two-stage planning

US 11022446	Kaehler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) United States Air Force (USAF)
APPLICANT(S)	APPLIED INVENTION, LLC (Burbank, California)
ASSIGNEE(S)	APPLIED INVENTION, LLC (Burbank, California)
INVENTOR(S)	Adrian Kaehler (Los Feliz, California); Kjerstin Williams (Los Angeles, California); Mark E. Duttweiler (Sherman Oaks, California)
ABSTRACT	A plan through a space having a near field and a far field is determined. Using a sensor device, measurements of the far field are obtained and stored in an electronic memory. A processor uses the measurements to determine the viability of each far field plan among a plurality of candidate far field plans. The processor also determines a flexibility score for each of the candidate far field plans and selects a composite plan comprising the viable far field plan having a highest flexibility score among the viable candidate far field plans.
FILED	Thursday, July 25, 2019
APPL NO	16/522456
ART UNIT	3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/34 (20130101) G01C 21/3407 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0212 (20130101) G05D 2201/0213 (20130101)
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11022489 — Portable multi-spectrometry system for chemical and biological sensing in atmospheric air

US 11022489	Ng et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC) Secretary of the Navy (SECNAV)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Kin Chiu Ng (Fresno, California); Subrata Sanyal (Eastvale, California)
ABSTRACT	The invention relates to a portable multi-spectrometry system for chemical and biological sensing in atmospheric air. A portable, spectrometric system integrates multiple spectroscopy theories, combines their advantageous features, and fills the gaps for their limitations. The combined spectrometry system with operations for PLS, IRAS, MAS, MFS, RSS, and MS, will detect particles and chemicals, directly and sequentially, in the same air-stream.
FILED	Thursday, March 28, 2019
APPL NO	16/368171
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/0272 (20130101) G01J 3/0294 (20130101) Original (OR) Class G01J 3/4406 (20130101) G01J 3/4412 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/3103 (20130101) G01N 21/3504 (20130101) G01N 21/6404 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101)
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11022529 — Sizable tunable enrichment platform for capturing nano particles in a fluid

US 11022529	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) United States Air Force (USAF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI) Department of Agriculture (USDA)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Siyang Zheng (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Yin-Ting Yeh (State College, Pennsylvania); Yi Tang (State College, Pennsylvania); Huaguang Lu (State College, Pennsylvania); Nestor Perea Lopez (State College, Pennsylvania); Yiqiu Xia (State College, Pennsylvania)
ABSTRACT	The invention provides enrichment platform devices for size-based capture of particles in solution. The enrichment platform device is useful for label-free capture of any particle. The invention relates to enrichment platform devices using nanowires and vertically aligned carbon nanotubes. The invention provides methods for making the enrichment platform devices. The invention provides methods for using the enrichment platform devices for filtering particles, capturing particles, concentrating particles, and releasing viable particles.
FILED	Friday, February 07, 2020
APPL NO	16/784507
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/12 (20130101) B01L 2300/041 (20130101) B01L 2300/0681 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) Original (OR) Class G01N 1/4077 (20130101) G01N 33/552 (20130101) G01N 33/54346 (20130101) G01N 33/56983 (20130101) G01N 2001/4088 (20130101) G01N 2333/11 (20130101)
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11022533 — Method of controlling particles size of fillers in extrudable compositions, compositions comprising the fillers and devices made from the compositions

US 11022533	Bruton et al.
FUNDED BY	Department of Defense (DOD) Defense Mobility Enterprise (DME) National Advanced Mobility Consortium (NAMC) Department of the Army (DOA) U.S. Army Contracting Command (ACC) U.S. Army
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Eric Alan Bruton (Lake St. Louis, Missouri); Loyal Bruce Shawgo (O'Fallon, Missouri)
ABSTRACT	A method of controlling a particle size distribution of a filler in an extrudable composition comprises introducing an extrudable composition comprising a polymer matrix material and a filler into an extruder, the filler having a first average particle size that is larger than a target average particle size. The extrudable composition is extruded one or more times using the extruder to reduce the size of the filler from the first average particle size to a reduced average particle size, the reduced average particle size being within 10% of the target average particle size.
FILED	Monday, May 06, 2019
APPL NO	16/404297
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0227 (20130101) Original (OR) Class G01N 2015/0277 (20130101)
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11022541 — Polarimetric detection of foreign fluids on surfaces

US 11022541	Chenault
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army
APPLICANT(S)	Polaris Sensor Technologies, Inc. (Huntsville, Alabama)
ASSIGNEE(S)	Polaris Sensor Technologies, Inc. (Huntsville, Alabama)
INVENTOR(S)	David B. Chenault (Huntsville, Alabama)
ABSTRACT	A method for detecting the presence of foreign fluids on surface comprises estimating an expected polarization response for a foreign fluid desired to be detected. Oil from an oil spill is one such foreign fluid. A polarimeter records raw image data of a surface (e.g., the surface of water) to obtain polarized images of the surface. IR and polarization data products are computed from the polarized images. The IR and polarization data products are converted to multi-dimensional data set to form multi-dimensional imagery. Contrast algorithms are applied to the multi-dimensional imagery to form enhanced contrast images, from which foreign fluids can be automatically detected.
FILED	Tuesday, July 30, 2019
APPL NO	16/526503
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Original (OR) Class G01N 25/00 (20130101) G01N 33/1833 (20130101) G01N 2021/1793 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/2036 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 2207/10048 (20130101) G06T 2207/30181 (20130101)
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11022605 — Multi-component in vitro system to deduce cell signaling pathways by electronic stimulation patterns

US 11022605	Hickman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	James Hickman (Orlando, Florida); Lee Kumanchik (Orlando, Florida); Navaneetha Santhanam (Orlando, Florida)
ABSTRACT	Disclosed herein are cell culture analog devices, systems and methods for applying stimuli to components containing different cell types and recording the cell responses before, during, and after a stimulus (for example, a drug, metabolite, toxin, or electrical stimulus) is introduced. Responses can be stored to a database and compared to previous results. By analyzing how each cell type responds to various stimulation parameters, for example, by using multivariate analyses, cell signaling pathway information can be determined or new pathways can be discovered. In some implementations, an individual component interfaces with a specific cell type. This facilitates readout of the cell response to the stimulation. Various components can also interface with each other, such that the behavior of one cell type can affect a cell type in another component. Once assembled, the system is plugged into readout electronics and a programmable electrical stimulator.
FILED	Wednesday, August 16, 2017
APPL NO	16/328417
ART UNIT	1799 — Organic Chemistry
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5014 (20130101) Original (OR) Class G01N 33/5029 (20130101)
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11022762 — Optical fiber connectors for rotational alignment

US 11022762	Singer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Chiral Photonics, Inc. (Pine Brook, New Jersey)
ASSIGNEE(S)	Chiral Photonics, Inc. (Pine Brook, New Jersey)
INVENTOR(S)	Jonathan Singer (New Hope, Pennsylvania); Victor Il'ich Kopp (Fair Lawn, New Jersey); Christopher W. Draper (Allendale, New Jersey); Zhou Shi (Pine Brook, New Jersey); Norman Chao (Brooklyn, New York)
ABSTRACT	An optical fiber connector configured to rotationally align a first optical fiber with a second optical fiber is provided. The connector can include at least two rotational alignment features. At least one of the two rotational alignment features can include at least one ferrule configured to hold at least the first optical fiber.
FILED	Wednesday, December 11, 2019
APPL NO	16/710463
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/383 (20130101) G02B 6/3851 (20130101) G02B 6/3853 (20130101) G02B 6/3874 (20130101) Original (OR) Class G02B 6/3885 (20130101)
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11022823 — Switchable optical filter for imaging and optical beam modulation

US 11022823	Syllaios
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army
APPLICANT(S)	University of North Texas (Denton, Texas)
ASSIGNEE(S)	University of North Texas (Denton, Texas)
INVENTOR(S)	Athanasios J. Syllaios (Denton, Texas)
ABSTRACT	switchable optical filter that is based on carrier injection induced semiconductor to metal phase transition (SMT) of vanadium oxide-based (e.g., VO₂) thin films may reversibly change from optically transparent to opaque while undergoing such phase transition. Electrical carrier injection may be established by an electric field or by photoexcitation. The SMT may also be induced by a combination of applying an electric field and optical flux. Such a switchable optical filter, when inserted in the optical path of an optical radiation sensor, may be used to control and/or limit high power optical beams, such as a laser beam impinging on one or more sensor elements. Since the SMT may be configured to occur at ultrafast time scales (e.g., approximately 100 femtoseconds), it may also act as a beam shutter and/or as a fast optical beam modulator.
FILED	Wednesday, August 08, 2018
APPL NO	16/058759
ART UNIT	2872 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/015 (20130101) Original (OR) Class G02F 2201/38 (20130101) G02F 2203/01 (20130101)
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11023275 — Technologies for queue management by a host fabric interface

US 11023275	Dinan et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts); Timo Schneider (Hudson, Massachusetts)
ABSTRACT	Technologies for managing a queue on a compute device are disclosed. In the illustrative embodiment, the queue is managed by a host fabric interface of the compute device. Queue operations such as enqueuing data onto the queue and dequeuing data from the queue may be requested by remote compute devices by sending queue operations which may be processed by the host fabric interface. The host fabric interface may, in some embodiments, fully manage the queue without any assistance from the processor of the compute device. In other embodiments, the processor of the compute device may be responsible for certain tasks, such as garbage collection.
FILED	Thursday, February 09, 2017
APPL NO	15/428282
ART UNIT	2195 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/46 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 9/5016 (20130101)
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11023625 — Computational accelerator architecture for change control in model-based system engineering

US 11023625	Eck et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Christopher R. Eck (Dunedin, Florida); Cassandra L. Wellman (St. Petersburg, Florida); Jagannath Chirravuri (Medfield, Massachusetts)
ABSTRACT	A computational accelerator architecture facilitates change management of works in a model-based system engineering (MBSE) system in which each of the MBSE works includes a plurality of separately-identifiable statements. A linkage data store stores statement-wise, variable-strength linkages between certain statements of the MBSE works, where the linkages are indicative of associations between those certain statements. A revision control engine detects changes made to statements of MBSE works, and selectively indicates calls for revision of other statements in response to those changes based on respective strengths of linkages associated with the changed statements.
FILED	Thursday, January 10, 2019
APPL NO	16/244420
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 16/211 (20190101) G06F 30/00 (20200101) Original (OR) Class
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11023808 — System and method of modeling visual perception V1 area

US 11023808	Jiang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Qin Jiang (Park Oaks, California); Narayan Srinivasa (Oak Park, California)
ABSTRACT	A system to detect a feature in an input image comprising a processor to evaluate a model including: four layers including: a supragranular layer, a granular layer, a first infragranular layer, and a second infragranular layer, each of the layers including a base connection structure including: an excitatory layer including a excitatory neurons arranged in a two dimensional grid; and an inhibitory layer including a inhibitory neurons arranged in a two dimensional grid; within-layer connections between the neurons of each layer in accordance with a Gaussian distribution; between-layer connections between the neurons of different layers, the probability of a neuron of a first layer of the different layers to a neuron of a second layer of the different layers in accordance with a uniform distribution; and input connections from lateral geniculate nucleus (LGN) neurons of an input LGN layer to the granular layer in accordance with a uniform distribution.
FILED	Thursday, October 24, 2019
APPL NO	16/663195
ART UNIT	2137 — Memory Access and Control
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/082 (20130101) Original (OR) Class G06N 3/0635 (20130101)
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11023840 — Scenario planning and risk management

US 11023840	Chang et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Yuan-Chi Chang (Armonk, New York); Mark D. Feblowitz (Winchester, Massachusetts); Nagui Halim (Yorktown Heights, New York); Stuart S. Horn (Southbury, Connecticut); Edward J. Pring (Yorktown Heights, New York); Anton V. Riabov (Ann Arbor, Michigan); Edward W. Shay (White Plains, New York); Shirin Sohrabi Araghi (Port Chester, New York); Deepak S. Turaga (Elmsford, New York); Octavian Udrea (Ossining, New York); Fang Yuan (Chappaqua, New York); Peter Zimmer (Danbury, Connecticut)
ABSTRACT	Techniques for scenario planning are provided. In one example, a computer-implemented method can comprise analyzing, by a device operatively coupled to a processor, content using a topic model. The content can be associated with a defined source and is related to one or more current events. The computer-implemented method can also comprise determining, by the device, one or more portions of the analyzed content that are relevant to one or more key risk drivers using a risk driver model. The computer-implemented method can also comprise aggregating, by the device, the determined one or more portions into one or more emerging storylines based on values of one or more attributes of the topic model.
FILED	Friday, January 27, 2017
APPL NO	15/418377
ART UNIT	3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Electric Digital Data Processing G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0635 (20130101) Original (OR) Class
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11024291 — Real-time class recognition for an audio stream

US 11024291	Castan Lavilla et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI INTERNATIONAL (Menlo Park, California)
INVENTOR(S)	Diego Castan Lavilla (Mountain View, California); Harry Bratt (Mountain View, California); Mitchell Leigh McLaren (Alderley, Australia)
ABSTRACT	In an embodiment, the disclosed technologies include automatically recognizing speech content of an audio stream that may contain multiple different classes of speech content, by receiving, by an audio capture device, an audio stream; outputting, by one or more classifiers, in response to an inputting to the one or more classifiers of digital data that has been extracted from the audio stream, score data; where a score of the score data indicates a likelihood that a particular time segment of the audio stream contains speech of a particular class; where the one or more classifiers use one or more machine-learned models that have been trained to recognize audio of one or more particular classes to determine the score data; using a sliding time window process, selecting particular scores from the score data; using the selected particular scores, determining and outputting one or more decisions as to whether one or more particular time segments of the audio stream contain speech of one or more particular classes; where the one or more decisions are outputted within a real-time time interval of the receipt of the audio stream; where the one or more decisions are used by downstream processing of the audio stream to control any one or more of the following: labeling the audio stream, segmenting the audio stream, diarizing the audio stream.
FILED	Wednesday, March 27, 2019
APPL NO	16/366751
ART UNIT	2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/04 (20130101) G10L 15/005 (20130101) G10L 15/08 (20130101) Original (OR) Class G10L 15/16 (20130101) G10L 17/06 (20130101) G10L 17/18 (20130101)
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11024348 — Memory array with reduced read power requirements and increased capacity

US 11024348	Lynch et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	John K. Lynch (West Lafayette, Indiana); Pedro P. Irazoqui (West Lafayette, Indiana)
ABSTRACT	An electronic memory array includes a plurality of memory domains, a current controller, and a selector device. Each memory domain includes a plurality of bit cells. The current controller includes a current controller output electrically connectable to said plurality of memory domains and is configured to control a bit cell current. The selector device is electrically connected to the current controller and the plurality of memory domains. The selector device is configured to selectively electrically connect the current controller output to only a select one of said memory domains, such that the current controller controls only the bit cell current of the bit cells of the select memory domain.
FILED	Thursday, February 20, 2020
APPL NO	16/795787
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 7/08 (20130101) G11C 7/12 (20130101) Original (OR) Class G11C 7/14 (20130101) G11C 7/065 (20130101) G11C 7/106 (20130101) G11C 7/1051 (20130101) G11C 11/419 (20130101) G11C 11/565 (20130101) G11C 11/4091 (20130101) G11C 11/4094 (20130101)
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11024447 — Two-dimensional materials integrated with multiferroic layers

US 11024447	Jonker
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Secretary of the Navy (SECNAV)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Berend T. Jonker (Waldorf, Maryland)
ABSTRACT	The invention relates to heterostructures including a layer of a two-dimensional material placed on a multiferroic layer. An ordered array of differing polarization domains in the multiferroic layer produces corresponding domains having differing properties in the two-dimensional material. When the multiferroic layer is ferroelectric, the ferroelectric polarization domains in the layer produce local electric fields that penetrate the two-dimensional material. The local electric fields can influence properties of the two-dimensional material, including carrier density, transport properties, optical properties, surface chemistry, piezoelectric-induced strain, magnetic properties, and interlayer spacing. Methods for producing the heterostructures are provided. Devices incorporating the heterostructures are also provided, including tunable sensors, optical emitters, and programmable logic gates.
FILED	Tuesday, November 21, 2017
APPL NO	15/819929
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/414 (20130101) G01N 27/4146 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/009 (20130101) Original (OR) Class H01F 10/1933 (20130101) H01F 10/3222 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/778 (20130101) H01L 29/1606 (20130101) H01L 29/7391 (20130101) H01L 29/66984 (20130101) H01L 29/78391 (20140902)
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11024624 — Devices and methods to control clamping devices

US 11024624	Savanth et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Arm Limited (Cambridge, United Kingdom); The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	Arm Limited (Cambridge, United Kingdom); The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Parameshwarappa Anand Kumar Savanth (Cambridge, United Kingdom); Fabrice Blanc (Vinay, France); David Theodore Blaauw (Ann Arbor, Michigan); Sechang Oh (Ann Arbor, Michigan); In Hee Lee (Ann Arbor, Michigan)
ABSTRACT	In a particular implementation, an apparatus to control clamping devices includes a first control circuit and a second control circuit. The first control circuit is responsive to a detection signal and generates a first drive signal to control a body diode of a clamping device. The second control circuit is responsive to the detection signal and generates a second drive signal to control the gate terminal of the clamping device.
FILED	Tuesday, July 24, 2018
APPL NO	16/044231
ART UNIT	2839 — Organic Chemistry
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0277 (20130101) Original (OR) Class Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) H02H 9/046 (20130101)
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11024790 — Single-photon single-flux coupled detectors

US 11024790	Onen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Research Office (ARO)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Oguzhan Murat Onen (Boston, Massachusetts); Marco Turchetti (Cambridge, Massachusetts); Karl K. Berggren (Arlington, Massachusetts); Brenden Butters (Cambridge, Massachusetts); Mina Bionta (Somerville, Massachusetts); Phillip Donald Keathley (Natick, Massachusetts)
ABSTRACT	A device that is a combination of a superconducting nanowire single-photon detector and a superconducting multi-level memory. These devices can be used to count a number of photons impinging on the device through single-photon to single-flux conversion. Electrical characterization of the device demonstrates single-flux quantum (SFQ) separated states. Optical measurements using attenuated laser pulses with different mean photon number, pulse energies and repetition rates are shown to differentiate single-photon detection from other possible phenomena, such as multiphoton detection and thermal activation. Array devices and methods are also discussed.
FILED	Monday, August 24, 2020
APPL NO	17/000959
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) H01L 39/10 (20130101) Original (OR) Class H01L 39/18 (20130101)
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11024848 — Thermally self-chargeable flexible energy storage device and method of forming and operating the same

US 11024848	Yu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Choongho Yu (College Station, Texas); Suk Lae Kim (College Station, Texas)
ABSTRACT	An energy storage device and method of forming and operating the same. In one embodiment, the energy storage device includes a positive electrode including a first redox polymer deposited on a first conductive porous substrate. The energy storage device also includes a solid-state polyelectrolyte separator operative as a voltage generator, and a negative electrode including a second redox polymer deposited on a second conductive porous substrate, thereby forming an electrochemical cell.
FILED	Friday, February 17, 2017
APPL NO	15/999855
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/606 (20130101) Original (OR) Class H01M 4/663 (20130101) H01M 10/08 (20130101) H01M 10/36 (20130101)
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11024876 — Composite membrane comprising solid electrolyte, method of making said composite membrane, and electrochemical cell comprising said composite membrane

US 11024876	Xu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Army (DOA) United States Army (USA) National Aeronautics and Space Administration (NASA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Giner, Inc. (Newton, Massachusetts)
ASSIGNEE(S)	GINER, INC. (Newton, Massachusetts)
INVENTOR(S)	Hui Xu (Acton, Massachusetts); Jarrod D. Milshtein (Cambridge, Massachusetts); Katherine Harrison (Arlington, Massachusetts); Mario Moreira (Hudson, Massachusetts); Brian Rasimick (Boston, Massachusetts)
ABSTRACT	A composite membrane that is suitable for use in an electrochemical cell, an electrochemical cell including the composite membrane, and a method of making the composite membrane. In one embodiment, the composite membrane includes a porous support and a solid electrolyte. The porous support is a unitary structure made of a polymer that is non-conductive to ions. The porous support is shaped to include a plurality of straight-through pores. The solid electrolyte has alkali ion conductivity and preferably completely fills at least some of the pores of the porous support. A variety of techniques may be used to load the solid electrolyte into the pores. According to one technique, the solid electrolyte is melted and then poured into the pores of the porous support. Upon cooling, the electrolyte re-solidifies, forming a monolithic structure within the pores of the porous support.
FILED	Wednesday, November 01, 2017
APPL NO	15/801118
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/02 (20130101) H01M 4/13 (20130101) H01M 10/052 (20130101) H01M 10/0486 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101)
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11024937 — High power broadband terahertz emitter with enhanced stability and beam polarity

US 11024937	Wu et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Secretary of the Navy (SECNAV)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Dong Ho Wu (Olney, Maryland); Louis M. Pecora (Alexandria, Virginia); Christopher Kim (Lorton, Virginia)
ABSTRACT	Systems and methods are provided for enhancing the terahertz power output of a terahertz beam while increasing its stability and its beam polarity by implementing a pair of pinched ripple electrodes and a small flat section in the middle of each electrode. By using tight control over the design parameters and by exploiting the plasmonic effect and the superradiance effect, systems and methods according to embodiments of the present disclosure can achieve a dramatic improvement in the terahertz output power and beam quality as well as the beam stability.
FILED	Friday, May 31, 2019
APPL NO	16/427701
ART UNIT	2884 — Optics
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/108 (20130101) H01L 31/0224 (20130101) H01L 31/0304 (20130101) H01L 31/022408 (20130101) Antennas, i.e Radio Aerials H01Q 1/02 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 1/00 (20130101)
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11024950 — Wideband laser-induced plasma filament antenna with modulated conductivity

US 11024950	Hening et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Secretary of the Navy (SECNAV) Space and Naval Warfare Systems (SPAWAR)
APPLICANT(S)	United States Government as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S)	United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Alexandru Hening (San Diego, California); Ryan P. Lu (San Diego, California); Ayax D. Ramirez (Chula Vista, California); Britanny Lynn (San Diego, California)
ABSTRACT	An antenna comprising: a radio frequency (RF) coupler; a transceiver communicatively coupled to the RF coupler; a laser configured to generate a plurality of femtosecond laser pulses so as to create, without the use of high voltage electrodes, a laser-induced plasma filament (LIPF) in atmospheric air, wherein the laser is operatively coupled to the RF coupler such that RF energy is transferred between the LIPF and the RF coupler; and wherein the laser is configured to modulate a characteristic of the laser pulses at a rate within the range of 1 Hz to 1 GHz so as to modulate a conduction efficiency of the LIPF thereby creating a variable impedance LIPF antenna.
FILED	Friday, November 30, 2018
APPL NO	16/206280
ART UNIT	2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/26 (20130101) Original (OR) Class H01Q 3/01 (20130101) H01Q 9/16 (20130101) H01Q 19/108 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101)
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11025215 — High input impedance, high dynamic range, common-mode-interferer tolerant sensing front-end for neuromodulation systems

US 11025215	Chandrakumar et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Hariprasad Chandrakumar (Los Angeles, California); Dejan Markovic (Los Angeles, California)
ABSTRACT	Neuromodulation systems in accordance with embodiments of the invention can use a feed-forward common-mode cancellation (CMC) path to attenuate common-mode (CM) artifacts appearing at a voltage input, thus allowing for the simultaneous recording of neural data and stimulation of neurons. In several embodiments of the invention, the feed-forward CMC path is utilized to attenuate the common-mode swings at V_in,CM, which can restore the linear operation of the front-end for differential signals. In several embodiments, the neuromodulation system may utilize an anti-alias filter (AAF) that includes a duty-cycles resistor (DCR) switching at a first frequency f₁, followed by a DCR switching at a second frequency f₂. The AAF allows for a significantly reduced second frequency f₂that enables the multi-rate DCR to increase the maximum realizable resistance, which is dependent upon the frequency ratio f₁/f₂.
FILED	Thursday, December 07, 2017
APPL NO	16/467456
ART UNIT	2843 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/7217 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Amplifiers H03F 1/26 (20130101) H03F 1/56 (20130101) H03F 3/45475 (20130101) Original (OR) Class H03F 2200/261 (20130101) H03F 2200/459 (20130101) H03F 2203/45138 (20130101)
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11025273 — Reducing error in data compression

US 11025273	Sample
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Secretary of the Navy (SECNAV)
APPLICANT(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	John T. Sample (Pearl River, Louisiana)
ABSTRACT	Systems and methods are provided for reducing error in data compression and decompression when data is transmitted over low bandwidth communication links, such as satellite links. Embodiments of the present disclosure provide systems and methods for variable block size compression for gridded data, efficiently storing null values in gridded data, and eliminating growth of error in compressed time series data.
FILED	Tuesday, April 09, 2019
APPL NO	16/378766
ART UNIT	2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 11/076 (20130101) G06F 11/0709 (20130101) Coding; Decoding; Code Conversion in General H03M 7/6041 (20130101) Original (OR) Class Transmission H04B 7/185 (20130101)
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11025287 — Interference cancellation system

US 11025287	Jensen
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Rockwell Collins, Inc. (Cedar Rapids, Iowa)
ASSIGNEE(S)	Rockwell Collins, Inc. (Cedar Rapids, Iowa)
INVENTOR(S)	Dana J. Jensen (Marion, Iowa)
ABSTRACT	Embodiments of the inventive concepts disclosed herein are directed to a system for cancelling interference. The system may include a first antenna and a second antenna spatially separated from the first antenna. The system may include a first time delay unit, coupled to the first antenna, and configured to apply a first time delay and first power gain on a first signal received by the first antenna. The system may include a control circuit, coupled to the first time delay unit, and configured to determine the first time delay and first power gain to cause a modified version of the first signal and a second signal, received by the second antenna, to be aligned in time and power levels.
FILED	Monday, February 17, 2020
APPL NO	16/792350
ART UNIT	2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Transmission H04B 1/126 (20130101) Original (OR) Class H04B 1/1018 (20130101) H04B 1/1036 (20130101) H04B 1/1081 (20130101)
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11025600 — System for de-duplicating network coded distributed storage and related techniques

US 11025600	Medard et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Muriel Medard (Belmont, Massachusetts); Prakash Narayana Moorthy (Framingham, Massachusetts); Vitaly Abdrashitov (Somerville, Massachusetts)
ABSTRACT	Methods for encoding a file and de-duplicating a coded packet of the file are presented. The encoding method includes: identifying a file to be stored; encoding the file to generate a plurality of coded packets; generating a hash code associated with the file; distributing the plurality of coded packets to a plurality of storage nodes; and storing the hash code associated with the file in a hash server. The de-duplicating method includes: receiving a coded packet at a storage node; retrieving a hash code, from the hash server, corresponding to the coded packet; determining whether the coded packet has been stored in the storage node based upon the hash code; in response to determination that the coded packet has being stored, discarding the coded packet; and in response to determination that the coded packet has not being stored, storing the coded packet in the storage node.
FILED	Thursday, November 08, 2018
APPL NO	16/184272
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 16/256 (20190101) G06F 16/1827 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) H04L 61/103 (20130101) H04L 61/2007 (20130101) H04L 61/6086 (20130101) H04L 63/0471 (20130101) Original (OR) Class
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11025661 — Method for improving the security of a networked system by adjusting the configuration parameters of the system components

US 11025661	Soroush et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Hamed Soroush (San Jose, California); Shantanu Rane (Menlo Park, California)
ABSTRACT	One embodiment provides a method for facilitating security in a system of networked components. During operation, the system constructs a configuration graph that stores a first set of relationships between configuration parameters within a component and a second set of relationships between configuration parameters across different components. A relationship corresponds to a constraint and is indicated by one or more of: a range for a configuration parameter; and a conjunction or a disjunction of logical relationships between two or more configuration parameters. The system generates a set of candidate configuration parameter values that satisfy the constraints of the relationships in the configuration graph. The system selects, from the set of candidate configuration parameter values, a first set of configuration parameter values that optimizes a security objective function.
FILED	Thursday, December 13, 2018
APPL NO	16/219774
ART UNIT	2497 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 41/22 (20130101) H04L 41/0816 (20130101) H04L 41/0823 (20130101) H04L 43/045 (20130101) H04L 63/20 (20130101) H04L 63/1433 (20130101) Original (OR) Class
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11026351 — Computing apparatus with closed cooling loop

US 11026351	Kulkarni et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Devdatta P. Kulkarni (Olympia, Washington); Richard J. Dischler (Bolton, Massachusetts)
ABSTRACT	The present disclosure describes embodiments of apparatuses and methods related to a computing apparatus with a closed cooling loop thermally coupled to one or more processors disposed on a circuit board of the computing apparatus. The closed cooling loop circulates a dielectric fluid to absorb heat from the processor. A portion of the dielectric fluid is evaporated from the processor heat absorbed by the dielectric fluid. A heat exchanger is coupled to the circuit board and thermally coupled to the closed cooling loop. The heat exchanger is to include a coolant flow to remove heat from the dielectric fluid circulated through the portion of the closed cooling loop thermally coupled to the heat exchanger. A vapor portion of the dielectric fluid is condensed from the heat removed by the coolant flow. Other embodiments may be described and/or claimed.
FILED	Friday, September 25, 2015
APPL NO	15/754957
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 1/0203 (20130101) H05K 7/20327 (20130101) H05K 7/20809 (20130101) Original (OR) Class H05K 7/20818 (20130101) H05K 2201/064 (20130101)
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11026358 — Biopolymer-based electromagnetic interference shielding materials

US 11026358	Zang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) U.S. Air Force
APPLICANT(S)	Software Defined Technologies Inc. (Carlsbad, California)
ASSIGNEE(S)	SOFTWARE DEFINED TECHNOLOGIES, INC (Carlsbad, California)
INVENTOR(S)	De Yu Zang (Irvine, California); Michael M. Salour (Carlsbad, California); James G. Grote (Yellow Spring, Ohio)
ABSTRACT	An electromagnetic interference (EMI) shielded device which includes an object to be shielded and an EMI shielding material encompassing the object. The EMI shielding material is made up of, but not limited to a broadband biopolymer or polymer dissolved in organic solvents, and metal and carbon-based nano-powders or nanoparticles. The specific makeup of the shielding material and fabrication procedure of the shielding material is also included herein.
FILED	Monday, February 25, 2019
APPL NO	16/284507
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/32 (20130101) C09D 199/00 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0209 (20130101) H05K 1/0216 (20130101) H05K 3/1283 (20130101) H05K 9/009 (20130101) H05K 9/0022 (20130101) H05K 9/0083 (20130101) Original (OR) Class H05K 2201/0257 (20130101)
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Department of Energy (DOE)

11020042 — Seizure detection device

US 11020042	Arnold et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Technology and Engineering Solutions of Sandia, LLC (NTESS)
APPLICANT(S)	KNOW BIOLOGICAL, INC. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	Know Biological, Inc. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Gary Stephen Arnold (Cumming, Georgia); Matthew Wallace Moorman (Albuquerque, New Mexico); Joshua Jonathan Whiting (Albuquerque, New Mexico)
ABSTRACT	Example aspects of a collector for a seizure detection device, a seizure detection device, and a method of detecting a seizure are disclosed. The collector for a seizure detection device can comprise a collector material configured to collect volatile organic compounds given off from a patient's skin; a wrapping configured to isolate the collector material from an external environment; a heater comprising a heating element, the heating element configured to emit a thermal pulse to desorb the volatile organic compounds from the collector material; and a mesh layer configured to prevent the collector material from contacting the patient's skin, wherein the collector material is received between the wrapping and the mesh layer.
FILED	Thursday, May 14, 2020
APPL NO	16/874229
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/443 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/6833 (20130101) A61B 10/00 (20130101) A61B 2010/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/20 (20130101) G01N 30/64 (20130101) G01N 30/80 (20130101) G01N 2030/025 (20130101)
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11020507 — Hemorrhage management system

US 11020507	Maitland et al.
FUNDED BY	Department of Energy (DOE) Lawrence Livermore National Laboratory (LLNL) Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Duncan J. Maitland (College Station, Texas); Todd Lawrence Landsman (College Station, Texas); Tyler Joseph Touchet (Cypress, Texas); Elizabeth L. Cosgriff-Hernandez (College Station, Texas); Thomas S. Wilson (San Leandro, California)
ABSTRACT	An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (T_g) of the SMP foam to below 25° C. Other embodiments are described herein.
FILED	Thursday, March 14, 2019
APPL NO	16/353793
ART UNIT	3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00017 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) Original (OR) Class A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/46 (20130101) A61L 15/425 (20130101) A61L 24/0015 (20130101) A61L 24/0036 (20130101) A61L 24/0094 (20130101) A61L 24/0094 (20130101) A61L 2300/106 (20130101) A61L 2300/404 (20130101) A61L 2400/16 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/04 (20130101)
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11020711 — Nanoscale membrane for removing trace organic contaminants in a fluid and methods of making and using the same

US 11020711	Lin et al.
FUNDED BY	Department of Energy (DOE) UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Xiao-Min Lin (Naperville, Illinois); Kun Wu (Naperville, Illinois); Subramanian Sankaranarayanan (Naperville, Illinois)
ABSTRACT	A membrane for filtering one or more hydrophobic organic contaminants can include a porous nanostructure that includes one or more of a metal, a metal oxide, and a metal alloy nanostructure component functionalized with one or more amphiphilic ligands.
FILED	Friday, September 28, 2018
APPL NO	16/147534
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 61/08 (20130101) B01D 67/0093 (20130101) B01D 69/125 (20130101) B01D 71/022 (20130101) Original (OR) Class B01D 2239/0414 (20130101) B01D 2257/70 (20130101) B01D 2321/168 (20130101) B01D 2323/36 (20130101) B01D 2323/40 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101)
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11020797 — System and method for controlling oxidation of metals during freeform casting

US 11020797	Pascall et al.
FUNDED BY	Department of Energy (DOE) Lawrence Livermore National Laboratory (LLNL) Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Andrew J. Pascall (Livermore, California); Joshua David Kuntz (Livermore, California); Scott K. McCall (Livermore, California)
ABSTRACT	A system is disclosed for printing a component. The system may have a nozzle controlled for movement within a plane. The nozzle may be configured to dispense a molten metal. A substrate may be positioned within a reservoir. The substrate may receive the molten metal to form the component in a printing operation. A heated barrier material in a molten state may be contained within the reservoir for forming a liquid barrier between an atmosphere and the substrate. The nozzle has a tip which is submerged within the liquid barrier while dispensing the molten metal during the printing operation. The liquid barrier forms a barrier between an atmosphere in a vicinity of the substrate and the substrate.
FILED	Tuesday, September 25, 2018
APPL NO	16/141437
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class B22D 45/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201)
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11020933 — Friction reduction for engine components

US 11020933	Hsu et al.
FUNDED BY	Department of Energy (DOE) National Energy Technology Laboratory (NETL)
APPLICANT(S)	The George Washington University (Washington, District of Columbia)
ASSIGNEE(S)	The George Washington University (Washington, District of Columbia)
INVENTOR(S)	Stephen M. Hsu (Germantown, Maryland); Yang Jing (Washington, District of Columbia); Yufei Mo (Washington, District of Columbia); Dongyun Hua (Washington, District of Columbia); Ming Chen (Washington, District of Columbia)
ABSTRACT	The present invention relates to techniques for lowering friction between moving surfaces of, for example, an internal combustion engine. Friction reduction is achieved by adding texture modifications to surfaces that come in contact with each other. Texture modifications that reduce friction in accordance with the present invention include dimples of varying geometries and depths ion the surfaces of components. The present invention also relates to the fabrication technique for applying the texture to the surfaces. In another embodiment, the patterned soft mask is applied onto a large surface (flat or curved including cylindrical rollers surfaces) to be followed by electrochemical etching to imprint the textures onto the component And, in another embodiment, a diamond-like-carbon (DLC) film may be applied to the turbine component to also reduce friction.
FILED	Friday, March 01, 2019
APPL NO	16/290648
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 5/08 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) Original (OR) Class Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/02 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/20 (20130101) Indexing Scheme Relating to Materials, Material Properties or Material Characteristics for Machines, Engines or Pumps Other Than Non-positive-displacement Machines or Engines F05C 2253/08 (20130101) F05C 2253/083 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115) Y10T 428/24851 (20150115)
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11020939 — Nanofiber electrodes, fabricating methods and applications of same

US 11020939	Pintauro
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	Peter N. Pintauro (Nashville, Tennessee)
ABSTRACT	Nanofiber electrodes for electrochemical devices and fabricating methods of the same are disclosed. In one embodiment, the method includes forming a liquid mixture containing a catalyst, a first polymer of perfluoro sulfonic acid and a second polymer of polyethylene oxide, the first polymer of perfluoro sulfonic acid being pre-treated to remove protons in the first polymer by exchange with a cation species like Na+; and electro spinning the liquid mixture to generate electro spun fibers and deposit the generated fibers on a collector substrate to form a fiber electrode mat comprising a network of fibers, where each fiber has a plurality of particles of the catalyst distributed thereon.
FILED	Friday, November 16, 2018
APPL NO	16/764504
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 13/02 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8652 (20130101) H01M 4/8657 (20130101) H01M 4/8663 (20130101)
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11021274 — Cubesat system

US 11021274	Judd et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Laboratory (LANL) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Triad National Security, LLC (Triad)
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Stephen Judd (Los Alamos, New Mexico); Nicholas Dallmann (Los Alamos, New Mexico); Kevin McCabe (Santa Fe, New Mexico); Donald Enemark (Los Alamos, New Mexico); Michael Proicou (Los Alamos, New Mexico); Daniel Seitz (Los Alamos, New Mexico)
ABSTRACT	Small cubesat systems may be available for a lower cost, have a higher reliability, and be much simpler to use than conventional cubesats. A complete turnkey system solution may be provided, including the ground station and remote field units. The satellite, ground station, and field unit may be provided separately as kits that are ready to go out-of-the-box as soon as they arrive. This enables universities, researchers, and hobbyists to obtain and deploy their own functional satellites. Furthermore, theoretical designs and functionality may be rapidly prototyped and demonstrated, which allows for proof-of-concept without needing to build a larger, more expensive satellite system and hope that the new design or functionality works as intended.
FILED	Thursday, September 08, 2016
APPL NO	15/259152
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/641 (20130101) B64G 1/646 (20130101) Original (OR) Class B64G 2001/1092 (20130101)
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11021391 — High thermal expansion glass composites and uses thereof

US 11021391	Ewsuk
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Technology and Engineering Solutions of Sandia, LLC (NTESS)
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Kevin G. Ewsuk (Albuquerque, New Mexico)
ABSTRACT	The present invention relates to glass composites, including filled glass composites and uses thereof. In particular examples, the composites provide improved thermal expansion characteristics. Also described are methods of forming such composites, such as by adding a particle filler to a glass mixture.
FILED	Monday, December 16, 2019
APPL NO	16/715709
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Manufacture, Shaping, or Supplementary Processes C03B 32/02 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/097 (20130101) Original (OR) Class C03C 8/24 (20130101)
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11021441 — High solubility thioether quinones

US 11021441	Stahl et al.
FUNDED BY	Department of Energy (DOE) Pacific Northwest National Laboratory (PNNL)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Shannon S. Stahl (Madison, Wisconsin); James B. Gerken (Madison, Wisconsin)
ABSTRACT	Substituted hydroquinones and quinones and methods of synthesizing such compounds are disclosed herein. The substituted hydroquinones have the formula: while the substituted quinones have the corresponding oxidized structure (1,4-benzoquinones). One, two, three, or all four of R¹, R², R³and R⁴comprise a thioether moiety and a sulfonate moiety, and wherein each R¹, R², R³and R⁴that does not comprise a thioether and a sulfonate moiety sulfonate moiety is independently a hydrogen, an alkyl or an electron withdrawing group. The substituted hydroquinones and quinones are soluble in water, stable in aqueous acid solutions, and have a high reduction potential in the oxidized form. Accordingly, they can be used as redox mediators in emerging technologies, such as in mediated fuel cells or organic-mediator flow batteries.
FILED	Wednesday, March 18, 2020
APPL NO	16/822189
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 309/42 (20130101) Original (OR) Class C07C 319/14 (20130101) C07C 323/66 (20130101) Heterocyclic Compounds C07D 209/48 (20130101) C07D 231/18 (20130101) C07D 285/14 (20130101) C07D 487/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101)
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11021516 — Self-assembling peptide polymer

US 11021516	Ulijn et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) U.S. Air Force Department of Energy (DOE) UChicago Argonne, LLC (UCHICAGO) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Rein V. Ulijn (New York, New York); Ayala Lampel (Bronx, New York); Tell Tuttle (Glasgow, United Kingdom); Gary Scott (Glasgow, United Kingdom); Scott McPhee (New York, New York); Christopher Bettinger (Pittsburgh, Pennsylvania)
ABSTRACT	A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.
FILED	Monday, September 11, 2017
APPL NO	16/332231
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 5/0819 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101)
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11021523 — Cyanobacteriochromes active in the far-red to near-infrared

US 11021523	Lagarias et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	John Clark Lagarias (Davis, California); Nathan Clarke Rockwell (Davis, California)
ABSTRACT	The present invention provides a protein fusion construct comprising a far-red cyanobacteriochrome (CBCR) domain linked to a heterologous domain, wherein the far-red CBCR domain comprises a CBCR polypeptide and a tetrapyrrole chromophore. The invention also provides nucleic acids, expression cassettes, vectors, and host cells for expression of the far-red CBCR protein fusion constructs. Methods for detecting cellular components, methods for imaging biological structures, and method for modulating cellular processes using the protein fusion constructs are also provided.
FILED	Wednesday, August 22, 2018
APPL NO	16/109613
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0045 (20130101) A61K 49/0056 (20130101) Peptides C07K 14/36 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101)
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11021525 — Synthetic transcription factor and uses thereof

US 11021525	Chou et al.
FUNDED BY	Department of Energy (DOE) Lawrence Berkeley National Laboratory (LBNL)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Howard H. Chou (Berkeley, California); Jay D. Keasling (Berkeley, California); Sergey Zotchev (Trondheim, Norway)
ABSTRACT	The present invention provides for a synthetic transcription factor (TF) comprising a first peptide capable of binding a target ligand, a second peptide capable of binding a target DNA, and a peptide linker linking the first and second peptides. The present invention also provide for a system for modulating the mutagenesis frequency of a host cell. The host cell has a mutator rate (R) which is inversely proportional to a phenotypic trait (P).
FILED	Wednesday, June 10, 2015
APPL NO	14/735985
ART UNIT	1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/70 (20130101) C07K 2319/80 (20130101)
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11021615 — Removable smart sequestration coatings for hazardous metals

US 11021615	Sampathkumaran et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOEOS)
APPLICANT(S)	INNOSENSE LLC (Torrance, California)
ASSIGNEE(S)	INNOSENSE LLC (Torrance, California)
INVENTOR(S)	Uma Sampathkumaran (Torrance, California); Kevin H. Yu (Temple City, California); Raymond Winter (Riverside, California)
ABSTRACT	Materials are disclosed for the safe sequestration and removal of hazardous contaminants from a surface. The materials can be sprayed, rolled, painted, brushed or dip coated onto any surface and allowed to dry and/or cure at room temperature or drying/curing can be accelerated by the application of heat to form a coating that entraps the contaminant therein. The coating and the entrapped contaminant can then peeled from the surface and safely disposed of to minimize hazardous waste. The coating includes a colorimetric additive that is specific to the contaminant, the coating and the contaminant producing a visual indication of contamination.
FILED	Wednesday, May 31, 2017
APPL NO	15/610219
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/20 (20130101) Original (OR) Class C09D 5/32 (20130101) C09D 101/28 (20130101) C09D 175/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 21/94 (20130101) G01N 31/22 (20130101)
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11021661 — Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy

US 11021661	Strohm et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE) Battelle Memorial Institute (BATTELLE)
APPLICANT(S)	James J. Strohm (West Richland, Washington); John C. Linehan (Richland, Washington); Benjamin Q. Roberts (Richland, Washington); Douglas L. McMakin (Richland, Washington); David M. Sheen (Richland, Washington); Jeffrey W. Griffin (Kennewick, Washington); James A. Franz (Kennewick, Washington); Charlene Franz (Kennewick, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	James J. Strohm (West Richland, Washington); John C. Linehan (Richland, Washington); Benjamin Q. Roberts (Richland, Washington); Douglas L. McMakin (Richland, Washington); David M. Sheen (Richland, Washington); Jeffrey W. Griffin (Kennewick, Washington); James A. Franz (Kennewick, Washington)
ABSTRACT	Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.
FILED	Tuesday, February 21, 2012
APPL NO	13/401216
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/0093 (20130101) B01J 19/126 (20130101) B01J 2219/0086 (20130101) B01J 2219/00792 (20130101) B01J 2219/00822 (20130101) B01J 2219/00826 (20130101) B01J 2219/00835 (20130101) B01J 2219/0894 (20130101) B01J 2219/00941 (20130101) B01J 2219/1215 (20130101) B01J 2219/1227 (20130101) B01J 2219/1239 (20130101) B01J 2219/1245 (20130101) B01J 2219/1269 (20130101) B01J 2219/1272 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/00 (20130101) C10G 1/02 (20130101) C10G 1/08 (20130101) C10G 9/24 (20130101) C10G 15/08 (20130101) C10G 32/02 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 2001/4622 (20130101)
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11021721 — Genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and its metabolic intermediates

US 11021721	Beckham et al.
FUNDED BY	Department of Energy (DOE) Battelle Memorial Institute (BATTELLE) Office of Energy Efficiency and Renewable Energy (EERE) Alliance for Sustainable Energy, LLC (ASE) National Renewable Energy Laboratory (NREL) Pacific Northwest National Laboratory (PNNL) UT-Battelle, LLC (UT-BATTELLE) Oak Ridge National Laboratory (ORNL)
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado); Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen (Aachen, Germany); University of Stuttgart (Stuttgart, Germany)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado); University of Stuttgart (Stuttgart, Germany); UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Gregg Tyler Beckham (Golden, Colorado); Mary Ann Franden (Centennial, Colorado); Lahiru N. Jayakody (Wheat Ridge, Colorado); Nick Johannes Petrus Wierckx (Bemelen, Netherlands); Janosch Alexander Klebensberger (Stuttgart, Germany); Lars Mathias Blank (Dortmund, Germany); Wing-Jin Li (Cologne, Germany); Bernhard Hauer (Stuttgart, Germany); Nicholas S. Cleveland (Golden, Colorado); William E. Michener (Golden, Colorado); Jason Michael Whitham (Raleigh, North Carolina)
ABSTRACT	Presented herein are genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and producing polyhydroxyalkanoates.
FILED	Friday, July 20, 2018
APPL NO	16/041371
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/0006 (20130101) C12N 9/1022 (20130101) C12N 15/52 (20130101) C12N 2500/50 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/625 (20130101) Original (OR) Class Enzymes C12Y 101/03015 (20130101) C12Y 202/01005 (20130101)
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11022028 — Engine system and method including first and second turbochargers

US 11022028	Lusardi
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency Energy (ARPAE)
APPLICANT(S)	Caterpillar Inc. (Deerfield, Illinois)
ASSIGNEE(S)	Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S)	Christopher Lusardi (Peoria, Illinois)
ABSTRACT	An engine system includes an internal combustion engine having an intake passage, a first set of combustion chambers, a second set of combustion chambers, a first exhaust passage fluidly connected to the first set of combustion chambers, and a second exhaust passage fluidly connected to the second set of combustion chambers. The engine system includes a first turbocharger including a first compressor and a first turbine. The engine system also includes a second turbocharger including a second compressor and a second turbine, the second compressor connected in series with the first compressor, and the second turbine being in fluid communication with the second exhaust passage. The first and second turbines are connected in parallel such that the first turbine only receives exhaust flow from the first set of combustion chambers, and the second turbine only receives exhaust flow from the second set of combustion chambers.
FILED	Tuesday, May 07, 2019
APPL NO	16/405600
ART UNIT	3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 37/001 (20130101) Original (OR) Class F02B 37/013 (20130101) F02B 37/24 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/08 (20160201) Non-positive-displacement Pumps F04D 29/2216 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04111 (20130101) H01M 2008/1293 (20130101)
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11022429 — Method for real-time inspection of structural components

US 11022429	Stull et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Laboratory (LANL) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Triad National Security, LLC (Triad)
APPLICANT(S)	Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Nicholas D. Stull (Los Alamos, New Mexico); Eric Brian Flynn (Los Alamos, New Mexico); Matthew David Mascarenas (Lakeside, California)
ABSTRACT	A multi-mode approach for real-time inspection of structural components may be applied to rapid, wide area measurement of thickness of thick plate-like structures using full-field multi-mode response measurement and analysis. The approach may allow estimation of thickness from full-field multi-mode response to single-tone ultrasonic excitation in thick plates. The approach may utilize wavenumber information across all available wave modes in order to make wavenumber spectroscopy sensitive to changes in thickness for a broader range of nominal initial thicknesses.
FILED	Thursday, December 13, 2018
APPL NO	16/219581
ART UNIT	2877 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02084 (20130101) G01B 11/0666 (20130101) Original (OR) Class
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11022542 — On-chip spectroscopic sensors with optical fringe suppression

US 11022542	Green et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency Energy (ARPAE)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	William Green (Yorktown Heights, New York); Chu Cheyenne Teng (Princeton, New Jersey); Gerard Wysocki (Princeton, New Jersey); Eric Zhang (Yorktown Heights, New York)
ABSTRACT	An on-chip spectroscopic sensor includes a tunable diode laser. A laser driver for drives the tunable diode laser. An analyte test cavity receives a chemical sample and exposes the received chemical sample to light from the tunable diode laser. An optical detector detects light emerging from the analyte test cavity as a result of the laser exposure. A spectral analyzer determines a spectrum of the emerging light, matches and removes one or more known optical fringe patterns from the determined spectrum, and determines a composition or concentration of the chemical sample from the optical fringe pattern-removed spectrum.
FILED	Friday, July 05, 2019
APPL NO	16/504100
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/28 (20130101) G01J 3/42 (20130101) G01J 3/45 (20130101) G01J 2003/423 (20130101) G01J 2003/2869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) Original (OR) Class G01N 21/39 (20130101) G01N 21/274 (20130101) G01N 33/0047 (20130101) G01N 2021/399 (20130101) G01N 2201/1211 (20130101) G01N 2201/06113 (20130101)
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11022582 — Structures including a measurement coating and methods of forming the same

US 11022582	Ely
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Technology and Engineering Solutions of Sandia, LLC (NTESS) Sandia National Laboratories (SNL)
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	George Ray Ely (Albuquerque, New Mexico)
ABSTRACT	A structure includes a substrate and a coating applied over the substrate, the coating containing particles sized between 30 and 250 micrometers. A proportion of the particles to the carrier is between 40 and 70 by volume percentage. In response to excitation of the structure by a controllable excitation source, a first instrument monitors behavior of the particles to determine a first condition of the structure thereby. In response to an absence of excitation of the structure by the controllable excitation source, a second instrument monitors behavior of the particles to determine a second condition of the structure thereby.
FILED	Tuesday, August 15, 2017
APPL NO	15/677441
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/20 (20130101) G01N 29/043 (20130101) Original (OR) Class G01N 29/045 (20130101) G01N 2291/0231 (20130101)
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11022593 — Solid phase sampling device and methods for point-source sampling of polar organic analytes

US 11022593	Boggess et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S)	Andrew J. Boggess (Aiken, South Carolina); Stephen L. Crump (Martinez, Georgia); Thomas L. White (Evans, Georgia)
ABSTRACT	Sampling devices for sampling an aqueous source (e.g., field testing of ground water) for multiple different analytes are described. Devices include a solid phase extraction component for retention of a wide variety of targeted analytes. Devices include analyte derivatization capability for improved extraction of targeted analytes. Thus, a single device can be utilized to examine a sample source for a wide variety of analytes. Devices also include an isotope dilution capability that can prevent error introduction to the sample analysis and can correct for sample loss and degradation from the point of sampling until analysis as well as correction for incomplete or poor derivatization reactions. The devices can be field-deployable and rechargeable.
FILED	Thursday, October 25, 2018
APPL NO	16/170185
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/405 (20130101) G01N 33/1826 (20130101) Original (OR) Class
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11022717 — Distributed measurement of minimum and maximum in-situ stress in substrates

US 11022717	Ohanian, III et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOEOS)
APPLICANT(S)	Luna Innovations Incorporated (Roanoke, Virginia)
ASSIGNEE(S)	Luna Innovations Incorporated (Roanoke, Virginia); Tennessee Technological University (Cookeville, Tennessee)
INVENTOR(S)	Osgar John Ohanian, III (Blacksburg, Virginia); Daniel R. Vandenberge (Cookeville, Tennessee); Matthew Anthony Davis (Christiansburg, Virginia)
ABSTRACT	A system for performing distributed measurements of in-situ stress includes an expandable element with at least one fiber optic sensor. The expandable element can be positioned at various depths in a hole in a substrate. A pressurizing device expands (and contracts) the expandable element when the expandable element is inserted in the hole in the substrate to exert pressure on the hole wall. A pressure sensor provides a sensor output indicative of a pressure applied to the hole wall by the expandable element. The fiber optic sensor and an optical interrogator measure strain along a length of the sensor in a continuous, high spatial resolution manner Based on the measured strain and pressure sensor output, the system determines various properties of the substrate such as, minimum principal stress, maximum principal stress, and/or principal stress direction associated with one or more fractures in the substrate, as well as substrate modulus.
FILED	Tuesday, August 28, 2018
APPL NO	16/114376
ART UNIT	2886 — Optics
CURRENT CPC	Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 47/06 (20130101) E21B 47/135 (20200501) E21B 49/006 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/243 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 2021/4735 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/16 (20130101) Original (OR) Class
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11022981 — Control architecture for predictive and optimal vehicle operations in a single vehicle environment

US 11022981	Borhan
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency Energy (ARPAE)
APPLICANT(S)	Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S)	Cummins Inc. (Columbus, Indiana)
INVENTOR(S)	Hoseinali Borhan (Bloomington, Indiana)
ABSTRACT	There is disclosed a cloud computing control system for vehicle speed control and also for control of a vehicle in a platoon. The cloud computing control system determines a speed trajectory and neutral coasting command for a first vehicle of the platoon and a vehicle controller determines a reference speed for the first vehicle in response to the speed trajectory and the neutral coasting command, and is response to one or more vehicle specific factors associated with the first vehicle.
FILED	Wednesday, October 31, 2018
APPL NO	16/176947
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) B60W 2552/00 (20200201) B60W 2555/20 (20200201) B60W 2555/60 (20200201) Systems for Controlling or Regulating Non-electric Variables G05D 1/0027 (20130101) G05D 1/0088 (20130101) G05D 1/0221 (20130101) G05D 1/0223 (20130101) Original (OR) Class Traffic Control Systems G08G 1/22 (20130101)
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11023242 — Method and apparatus for asynchronous scheduling

US 11023242	Kalamatianos et al.
FUNDED BY	Department of Energy (DOE) Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California); ATI Technologies ULC (Markham, Canada)
ASSIGNEE(S)	ATI TECHNOLOGIES ULC (Markham, Canada); ADVANCED MICRO DEVICES, INC. (Sunnyvale, California)
INVENTOR(S)	John Kalamatianos (Boxborough, Massachusetts); Greg Sadowski (Boxborough, Massachusetts); Syed Zohaib M. Gilani (Markham, Canada)
ABSTRACT	A method and apparatus of asynchronous scheduling in a graphics device includes sending one or more instructions from an instruction scheduler to one or more instruction first-in/first-out (FIFO) devices. An instruction in the one or more FIFO devices is selected for execution by a single-instruction/multiple-data (SIMD) pipeline unit. It is determined whether all operands for the selected instruction are available for execution of the instruction, and if all the operands are available, the selected instruction is executed on the SIMD pipeline unit. The self-timed arithmetic pipeline unit (SIMD pipeline unit) is effectively encapsulated in a synchronous, (e.g., clocked by global clock), scheduler and register file environment.
FILED	Friday, January 27, 2017
APPL NO	15/417555
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/383 (20130101) G06F 9/384 (20130101) G06F 9/3001 (20130101) G06F 9/3824 (20130101) G06F 9/3836 (20130101) Original (OR) Class G06F 9/3851 (20130101) G06F 9/3871 (20130101) G06F 9/3877 (20130101) G06F 9/3887 (20130101) G06F 9/30036 (20130101) G06F 12/0875 (20130101) G06F 15/8007 (20130101) G06F 2212/452 (20130101)
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11023291 — Synchronization between processes in a coordination namespace

US 11023291	Jacob et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Philip Jacob (Congers, New York); Philip N. Strenski (Yorktown Heights, New York); Charles Johns (Austin, Texas)
ABSTRACT	A system and method of supporting point-to-point synchronization among processes/nodes implementing different hardware barriers in a tuple space/coordinated namespace (CNS) extended memory storage architecture. The system-wide CNS provides an efficient means for storing data, communications, and coordination within applications and workflows implementing barriers in a multi-tier, multi-nodal tree hierarchy. The system provides a hardware accelerated mechanism to support barriers between the participating processes. Also architected is a tree structure for a barrier processing method where processes are mapped to nodes of a tree, e.g., a tree of degree k to provide an efficient way of scaling the number of processes in a tuple space/coordination namespace.
FILED	Friday, May 10, 2019
APPL NO	16/409377
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/522 (20130101) Original (OR) Class G06F 9/546 (20130101) G06F 9/5072 (20130101)
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11023410 — Instructions for performing multi-line memory accesses

US 11023410	Roberts et al.
FUNDED BY	Department of Energy (DOE) Exascale Computing Project (ECP) PathForward Project (PATHFORWARD) Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S)	Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S)	ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
INVENTOR(S)	David A. Roberts (Wellesley, Massachusetts); Shenghsun Cho (Stonybrook, New York)
ABSTRACT	A system is described that performs memory access operations. The system includes a processor in a first node, a memory in a second node, a communication interconnect coupled to the processor and the memory, and an interconnect controller in the first node coupled between the processor and the communication interconnect. Upon executing a multi-line memory access instruction, the processor prepares a memory access operation for accessing, in the memory, a block of data including at least some of each of at least two lines of data. The processor then causes the interconnect controller to use a single remote direct memory access memory transfer to perform the memory access operation for the block of data via the communication interconnect.
FILED	Tuesday, September 11, 2018
APPL NO	16/127607
ART UNIT	2184 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 12/0862 (20130101) G06F 13/1673 (20130101) G06F 13/4027 (20130101) G06F 15/17331 (20130101) Original (OR) Class G06F 2212/1021 (20130101) G06F 2212/1024 (20130101) G06F 2212/6026 (20130101)
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11023579 — Malicious activity detection in a memory

US 11023579	Wheeler et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Technology and Engineering Solutions of Sandia, LLC (NTESS) Sandia National Laboratories (SNL)
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jason W. Wheeler (Albuquerque, New Mexico); Tu-Thach Quach (Albuquerque, New Mexico); Conrad D. James (Albuquerque, New Mexico); James Bradley Aimone (Albuquerque, New Mexico); Arun F. Rodrigues (Albuquerque, New Mexico)
ABSTRACT	A method and apparatus for monitoring a volatile memory in a computer system. Samples of compressed data from locations in the volatile memory in the computer system are read. Data in the volatile memory is reconstructed using the samples of compressed data. The data is an image of the volatile memory. The image enables determining whether an undesired process is present in the volatile memory.
FILED	Thursday, December 01, 2016
APPL NO	15/367026
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/562 (20130101) Original (OR) Class G06F 21/564 (20130101) G06F 2212/401 (20130101) G06F 2212/1052 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/145 (20130101)
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11024433 — Control rod damping system

US 11024433	Snuggerud
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S)	NuScale Power, LLC (Corvallis, Oregon)
INVENTOR(S)	Ross Douglas Snuggerud (Corvallis, Oregon)
ABSTRACT	A damping area or “dash pot” on the upper ends of control rods absorb energy from dropped control rod assemblies without narrowing the diameter of guide tubes. As a result, coolant can freely flow through the guide tubes reducing boiling water issues. The dampening area reduces a separation distance between an outside surface of the control rod and an inside surface of the guide tubes decelerating the control rods when entering a top end of the guide tubes. In another example, the dampening area may be located on a drive shaft. The dampening area may have a larger diameter than an opening in a drive shaft support member that decelerates the drive shaft when dropped by a drive mechanism.
FILED	Friday, December 29, 2017
APPL NO	15/858073
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Nuclear Reactors G21C 3/322 (20130101) G21C 3/3315 (20130101) G21C 7/11 (20130101) G21C 7/20 (20130101) Original (OR) Class G21C 7/117 (20130101) G21C 9/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101)
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11024465 — Mixed three-dimensional and two-dimensional perovskites and methods of making the same

US 11024465	Zhu et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Alliance for Sustainable Energy, LLC (ASE) National Renewable Energy Laboratory (NREL)
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Kai Zhu (Littleton, Colorado); Donghoe Kim (Seoul, South Korea)
ABSTRACT	An aspect of the present disclosure is a perovskite that includes A_{(n−1−nw+w)}A′_(wn−w)A″₂B_nX_{(3n−3zn+3z−4e+1)}X′_(3zn−3z)X″_4e, where each of A, A′, A″ are monovalent cations, B is a divalent cation, each of X, X′, and X″ are monovalent anions, 0<w≤1, 0<z≤1, 0<e≤1, and 1≤n≤100000.
FILED	Monday, September 16, 2019
APPL NO	16/571344
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/00 (20130101) C07F 7/24 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class H01G 9/2072 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/302 (20130101) H01L 31/0322 (20130101) H01L 51/0007 (20130101) H01L 51/0077 (20130101) H01L 51/4253 (20130101)
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11024734 — Three dimensional vertically structured electronic devices

US 11024734	Conway et al.
FUNDED BY	Department of Energy (DOE) Lawrence Livermore National Laboratory (LLNL) Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Adam Conway (Livermore, California); Sara Elizabeth Harrison (Fremont, California); Rebecca J. Nikolic (Oakland, California); Qinghui Shao (Fremont, California); Lars Voss (Livermore, California)
ABSTRACT	In one embodiment, a method of forming a vertical transistor includes forming a layer comprising a semiconductor material above a substrate, defining three dimensional (3D) structures in the layer, forming a second region in at least one vertical sidewall of each 3D structure, and forming an isolation region between the 3D structures. In another embodiment, an apparatus includes at least one vertical transistor, where the at least one vertical transistor includes: a substrate comprising a semiconductor material, an array of 3D structures above the substrate, and an isolation region positioned between the 3D structures. Each 3D structure includes the semiconductor material. Each 3D structure also includes a first region having a first conductivity type and a second region having a second conductivity type, the second region including a portion of at least one vertical sidewall of the 3D structure.
FILED	Wednesday, January 04, 2017
APPL NO	15/398652
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/0657 (20130101) H01L 29/2003 (20130101) H01L 29/7788 (20130101) H01L 29/7789 (20130101) H01L 29/7827 (20130101) Original (OR) Class H01L 29/8083 (20130101) H01L 29/66924 (20130101)
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11025025 — Integrated optics for high energy laser applications

US 11025025	Walton et al.
FUNDED BY	Department of Energy (DOE) Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Christopher C. Walton (Oakland, California); S. Mark Ammons (Oakland, California); Brian Bauman (Livermore, California); Robert C. Bickel (Walnut Creek, California); Willem H. De Vries (Livermore, California); Alexander Pertica (Livermore, California); Michael Pivovaroff (Oakland, California); Vincent Riot (Oakland, California)
ABSTRACT	An optical laser beam director assembly is disclosed. The beam director assembly includes a monolithic optics piece formed of transparent optical material, a laser source is coupled to the monolithic optics piece to provide a laser beam to the optics piece, and a beam steerer connected to the optics piece to direct the laser beam output from the optics piece onto a target.
FILED	Tuesday, November 27, 2018
APPL NO	16/202015
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/08 (20130101) G02B 27/30 (20130101) G02B 27/0977 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/16 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0071 (20130101) Original (OR) Class
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11026326 — Peripheral end face attachment of exposed copper layers of a first printed circuit board to the surface of a second printed circuit board by surface mount assembly

US 11026326	Takken et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Todd E. Takken (Brewster, New York); Xin Zhang (Yorktown Heights, New York); Yuan Yao (Tarrytown, New York); Andrew Ferencz (Southborough, Massachusetts)
ABSTRACT	A printed circuit board (PCB) structure and mounting assembly for joining two PCBs. A first PCB has a top and bottom surface faces and a peripheral end face separating the top and bottom surface. The first PCB has one or more conductive wire ends exposed at a surface of the peripheral end face; the exposed conductive wire ends forming multiple separate electrical contacts across the thickness and length of the PEF surface. A second PCB has a top surface face and one or more conductive pads exposed at the top surface at locations corresponding to locations of the multiple electrical contacts. A surface mount solder material is disposed on one or more exposed conductive pads for electrically connecting with corresponding the multiple electrical contacts. The disposed solder material stably joins the PEF surface of the first PCB to the top surface of the second PCB in a relative perpendicular orientation.
FILED	Thursday, August 01, 2019
APPL NO	16/528908
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/117 (20130101) H05K 1/0298 (20130101) Original (OR) Class H05K 3/366 (20130101) H05K 3/403 (20130101) H05K 13/04 (20130101) H05K 2201/0919 (20130101) H05K 2201/09145 (20130101)
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11026354 — Cooling methods for medium voltage drive systems

US 11026354	Ledezma et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	TECO-Westinghouse Motor Company (Round Rock, Texas)
ASSIGNEE(S)	TECO-Westinghouse Motor Company (Round Rock, Texas)
INVENTOR(S)	Enrique Ledezma (Austin, Texas); Bhaskara Palle (Round Rock, Texas); Rose Metzler (Cedar Park, Texas)
ABSTRACT	In one aspect, a medium voltage power converter includes a cabinet having: a power cube bay to house a plurality of power cubes, each of the plurality of power cubes adapted within a corresponding enclosure and comprising a low frequency front end stage, a DC link and a high frequency back end stage, the plurality of power cubes to couple to a high speed machine; and a plurality of first barriers adapted to isolate and direct a first flow of cooling air through one of the plurality of power cubes; and a transformer bay having at least one transformer to couple between a utility connection and the plurality of power cubes, the transformer bay including a plurality of cooling fans to cool the at least one transformer.
FILED	Monday, December 16, 2019
APPL NO	16/715013
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Boards, Substations, or Switching Arrangements for the Supply or Distribution of Electric Power H02B 1/565 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/4585 (20130101) H02M 7/003 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/08 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/202 (20130101) H05K 7/20154 (20130101) H05K 7/20254 (20130101) H05K 7/20572 (20130101) H05K 7/20609 (20130101) H05K 7/20927 (20130101) Original (OR) Class H05K 7/20936 (20130101)
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National Science Foundation (NSF)

11020001 — Ultrasonic network for wearable devices

US 11020001	Melodia et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Northeastern University (Boston, Massachusetts)
ASSIGNEE(S)	Northeastern University (Boston, Massachusetts)
INVENTOR(S)	Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT	An ultrasonic communication system and method provide a networking framework for wearable devices based on ultrasonic communications. The ultrasonic communication system and method incorporate a set of physical, data link, network and application layer functionalities that can flexibly adapt to application and system requirements to efficiently distribute information between ultrasonic wearable devices.
FILED	Thursday, April 11, 2019
APPL NO	16/381716
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0015 (20130101) Original (OR) Class A61B 5/0024 (20130101) A61B 5/0026 (20130101) A61B 5/0028 (20130101) A61B 5/0205 (20130101) A61B 5/02438 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) Transmission H04B 11/00 (20130101) Wireless Communication Networks H04W 84/18 (20130101)
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11020046 — Systems and methods for monitoring a patient

US 11020046	Lee et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Hanmin Lee (San Francisco, California); Sachin Rangarajan (San Francisco, California); Isabelle Chumfong (San Francisco, California)
ABSTRACT	Provided herein are methods and systems for monitoring a patient using a pressure-sensing device containing a pressure-sensitive region configured to selectively overlie a pressure ulcer-prone body part of the patient. In some embodiments, the pressure-sensing device includes a multilayered sensing unit containing a pressure-sensing layer to sense force and an adhesive layer configured to attach the pressure-sensing device to the body part. Also provided is a kit that includes the pressure-sensing device. The present methods, systems, and kits may find use in reducing the risk of pressure ulcer development in a patient.
FILED	Thursday, January 12, 2017
APPL NO	16/068847
ART UNIT	3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0022 (20130101) A61B 5/447 (20130101) Original (OR) Class A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/1115 (20130101) A61B 5/4848 (20130101) A61B 5/6833 (20130101) A61B 5/6892 (20130101) A61B 5/7225 (20130101) A61B 5/7242 (20130101) A61B 5/7275 (20130101) A61B 5/7405 (20130101) A61B 5/7455 (20130101) A61B 2562/046 (20130101) A61B 2562/0247 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101)
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11020491 — In vivo radical-mediated polymerization for targeted delivery of trophic factors

US 11020491	Lowe et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	Christopher Lowe (Piscataway, New Jersey); David I. Shreiber (Whitehouse Station, New Jersey); Emily DiMartini (Piscataway, New Jersey); Adam Gormley (New Brunswick, New Jersey)
ABSTRACT	The present invention provides a biocompatible conjugate for treating a disease or an injury. The conjugate contains a polymer covalently linked to one or more moieties each containing a polymerizable functional group. The conjugate forms a cross-linked polymer network after being exposed to an elevated level of free radicals associated with the disease or injury.
FILED	Thursday, June 14, 2018
APPL NO	16/009033
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/6935 (20170801) Original (OR) Class Compositions of Macromolecular Compounds C08L 33/06 (20130101) C08L 33/20 (20130101) C08L 33/26 (20130101) C08L 2203/02 (20130101)
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11020497 — Rod-shaped plant virus nanoparticles as imaging agent platforms

US 11020497	Steinmetz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S)	Nicole Steinmetz (San Diego, California); Michael Bruckman (Cleveland, Ohio)
ABSTRACT	A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
FILED	Tuesday, October 02, 2018
APPL NO	16/149828
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/1884 (20130101) A61K 49/1896 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/00031 (20130101)
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11020731 — Catalysts for selective coupling of olefins, and methods of making and using same

US 11020731	Goldman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Alan S. Goldman (Piscataway, New Jersey); Yang Gao (Piscataway, New Jersey)
ABSTRACT	The present invention relates in part to the unexpected discovery of novel complexes capable of catalyzing the selective dehydrogenative coupling of olefins. The invention further relates to the use of these complexes for the selective coupling of olefins.
FILED	Tuesday, October 30, 2018
APPL NO	16/175339
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/182 (20130101) B01J 31/2295 (20130101) Original (OR) Class B01J 2231/46 (20130101) B01J 2231/4205 (20130101) B01J 2531/0244 (20130101) B01J 2531/827 (20130101) B01J 2540/10 (20130101) Acyclic or Carbocyclic Compounds C07C 2/76 (20130101) C07C 2/76 (20130101) C07C 2/86 (20130101) C07C 11/167 (20130101) C07C 2531/22 (20130101)
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11020736 — High definition microdroplet printer

US 11020736	Abate et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Adam R. Abate (San Francisco, California); Adam R. Sciambi (San Francisco, California); Russell Cole (San Francisco, California); Zev Jordan Gartner (Pacifica, California)
ABSTRACT	Methods for delivering discrete entities including, e.g., cells, media or reagents to substrates are provided. In certain aspects, the methods include manipulating and/or analyzing qualities of the entities or biological components thereof. In some embodiments, the methods may be used to create arrays of microenvironments and/or for two and three-dimensional printing of tissues or structures. Systems and devices for practicing the subject methods are also provided.
FILED	Tuesday, August 27, 2019
APPL NO	16/552982
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2035/1034 (20130101)
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11021447 — Fluorescent halogen bonding arylethynyl scaffolds for anion recognition

US 11021447	Lohrman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Oregon (Eugene, Oregon); University of Montana (Missoula, Montana)
ASSIGNEE(S)	University of Oregon (Eugene, Oregon); University of Montana (Missoula, Montana)
INVENTOR(S)	Jessica Lohrman (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Michael M. Haley (Eugene, Oregon); Orion B. Berryman (Missoula, Montana); Asia M. Riel (Missoula, Montana); Daniel A. Decato (Missoula, Montana)
ABSTRACT	A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R¹⁰is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
FILED	Wednesday, May 01, 2019
APPL NO	16/401037
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 213/22 (20130101) C07D 213/90 (20130101) C07D 233/56 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101)
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11021489 — Polycyclic aromatic compound embodiments and methods of making and using the same

US 11021489	Haley et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Oregon (Eugene, Oregon)
ASSIGNEE(S)	University of Oregon (Eugene, Oregon)
INVENTOR(S)	Michael Haley (Eugene, Oregon); Justin Dressler (Eugene, Oregon); Joshua Barker (Eugene, Oregon)
ABSTRACT	Disclosed herein are polycyclic aromatic compound embodiments and methods of making and using such compounds. In some embodiments, the polycyclic aromatic compounds comprise an indenoindenodi(benzothiophene) skeleton. The polycyclic aromatic compound embodiments can be used in a variety of devices, such as electronic and/or electrooptical devices.
FILED	Friday, February 28, 2020
APPL NO	16/805382
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/04 (20130101) C07D 493/04 (20130101) C07D 495/04 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) H01L 51/0073 (20130101) H01L 51/0074 (20130101) H01L 51/0094 (20130101)
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11021516 — Self-assembling peptide polymer

US 11021516	Ulijn et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) U.S. Air Force Department of Energy (DOE) UChicago Argonne, LLC (UCHICAGO) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York); University of Strathclyde (Glasgow, United Kingdom); Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Rein V. Ulijn (New York, New York); Ayala Lampel (Bronx, New York); Tell Tuttle (Glasgow, United Kingdom); Gary Scott (Glasgow, United Kingdom); Scott McPhee (New York, New York); Christopher Bettinger (Pittsburgh, Pennsylvania)
ABSTRACT	A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.
FILED	Monday, September 11, 2017
APPL NO	16/332231
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 5/0819 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101)
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11021554 — Transition metal catalysts for olefin polymerization

US 11021554	Carrow et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Brad P Carrow (Princeton, New Jersey); Wei Zhang (Exton, Pennsylvania)
ABSTRACT	In one aspect, a chelating phosphine-phosphonic diamide (PPDA) ligand is described herein for constructing transition metal complexes operable for catalysis of olefin polymerization, including copolymerization of ethylene with polar monomer.
FILED	Wednesday, April 17, 2019
APPL NO	16/387100
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/28 (20130101) C07F 9/44 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/80 (20130101) C08F 4/7014 (20130101) C08F 4/7014 (20130101) C08F 10/02 (20130101) C08F 110/02 (20130101) C08F 210/02 (20130101) Original (OR) Class C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 210/02 (20130101) C08F 216/12 (20130101) C08F 216/18 (20130101) C08F 218/12 (20130101) C08F 220/00 (20130101) C08F 220/02 (20130101) C08F 220/06 (20130101) C08F 220/06 (20130101) C08F 220/10 (20130101) C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/44 (20130101) C08F 2410/01 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/02 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/03 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101) C08F 2500/10 (20130101)
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11021723 — System and method for biosynthesis

US 11021723	Coleman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Todd Prentice Coleman (La Jolla, California); Marianne Catanho (San Diego, California); Phillip Kyriakakis (San Diego, California)
ABSTRACT	Methods, systems, and devices are disclosed for in vivo production or biosynthesis of metabolites in foreign cells using the combination of (i) one or more ferredoxin dependent enzyme(s) and (ii) a ferredoxin (Fd)/ferredoxin-NADP⁺ reductase (FNR) system. The ferredoxin dependent enzymes and the Fd/FNR system are from the same species or from a different but matching species.
FILED	Thursday, May 04, 2017
APPL NO	16/098700
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 5/0215 (20130101) C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0095 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) C12P 13/14 (20130101) C12P 17/165 (20130101) Original (OR) Class Enzymes C12Y 103/07004 (20130101) C12Y 103/07005 (20130101) C12Y 118/01002 (20130101)
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11021724 — Materials and methods for alkene reduction of levoglucosenone by an alkene reductase

US 11021724	Stewart et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); AgroParisTech (Paris, France)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainsville, Florida); AfroParisTech (Paris, France)
INVENTOR(S)	Jon Dale Stewart (Orlando, Florida); Florent Allais (Bouy, France); Louis Michel Marie Mouterde (Reims, France)
ABSTRACT	The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (S)-γ-hydroxymethyl-α,β-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 from Pichia stipites and comprises the amino acid sequence of SEQ ID NO: I. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).
FILED	Thursday, March 29, 2018
APPL NO	16/490556
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/181 (20130101) Original (OR) Class Enzymes C12Y 106/99001 (20130101)
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11022115 — Controlled variable delivery external gear machine

US 11022115	Vacca et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Andrea Vacca (Lafayette, Indiana); Srinath Tankasala (Boston, Massachusetts)
ABSTRACT	A controlled variable delivery external gear machine (VD-EGM). The VD-EGM includes a housing, an inlet, a drive gear, a driven gear, the drive gear configured to engage the driven gear in an angular mesh zone, an outlet, a first slider comprising a first longitudinal portion connected to a second longitudinal portion such that longitudinal forces applied to the first and second longitudinal portions substantially cancel each other thereby requiring between about 0 N to about 20 N to longitudinally moving the first slider, selective positioning of the first slider configured to vary net operational volumes of fluid communication between the inlet and the outlet, for a given rotational speed of the drive gear, and a first drive mechanism coupled to the first slider and configured to cause the first slider to slide in a longitudinal direction.
FILED	Wednesday, May 30, 2018
APPL NO	15/993505
ART UNIT	3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2/18 (20130101) F04C 14/18 (20130101) Original (OR) Class F04C 2240/811 (20130101)
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11022500 — Systems and methods for thermometry and theranostic applications

US 11022500	Yuan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Baohong Yuan (Arlington, Texas); Shuai Yu (Mansfield, Texas); Tingfeng Yao (Arlington, Texas)
ABSTRACT	In one aspect, methods of measuring the temperature of an environment are described herein. In some embodiments, such a method comprises (a) disposing a population of ultrasound-switchable fluorophores in the environment, the population comprising n differing fluorophores having n differing switching threshold temperatures; (b) exposing the environment to an ultrasound beam to create an activation region having a temperature greater than or equal to one or more of the switching threshold temperatures; (c) disposing the fluorophores within the activation region to switch at least one fluorophore from an off state to an on state; (d) exposing the environment to up to n beams of electromagnetic radiation, thereby exciting at least one fluorophore in the on state; (e) detecting up to n photoluminescence signals emitted by the fluorophores; and (f) correlating the photoluminescence signals with up to n temperatures or temperature ranges.
FILED	Friday, June 02, 2017
APPL NO	16/304408
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/20 (20130101) Original (OR) Class
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11022501 — Apparatus and method for measuring temperature of batteries and internal battery components

US 11022501	Hsieh et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Feasible, Inc. (Berkeley, California)
ASSIGNEE(S)	Feasible, Inc. (Berkeley, California)
INVENTOR(S)	Andrew Gaheem Hsieh (Berkeley, California); Barry James Van Tassell (El Cerrito, California); Daniel Artemis Steingart (Princeton, New Jersey); Shaurjo Biswas (El Cerrito, California); Robert Charles Mohr (Berkeley, California)
ABSTRACT	Systems and methods for measuring temperature characteristics of a battery include one or more transducers coupled to the battery for transmitting and/or receiving sound waves through at least a portion of the battery. A temperature measurement unit is provided to determine a time-of-flight of sound waves through at least the portion of the battery based on transmitted and received sound waves through at least the portion of the battery, and to determine temperature characteristics of at least the portion of the battery based on the time-of-flight.
FILED	Friday, October 11, 2019
APPL NO	16/599562
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 31/382 (20190101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/486 (20130101)
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11022592 — Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor

US 11022592	Zang et al.
FUNDED BY	Department of Homeland Security (DHS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Ling Zang (Salt Lake City, Utah); Na Wu (Salt Lake City, Utah); Paul Slattum (Salt Lake City, Utah)
ABSTRACT	A chemiresistive vapor sensor compound for detecting target vapors can comprise a perylene-tetracarboxylic diimide (PTCDI) core according to structure (I): where R can be a morphology control group or -A′-D′, A and A′ can be independently a linking group, D and D′ can be independently a strong electron donor which transfers electrons to the PTCDI core sufficient to form an anionic PTCDI radical of the PTCDI core, and R1 to R8 can be independently a side group. A chemiresistive vapor sensor for detection of a target compound can comprise an assembly of nanofibers formed of the chemiresistive sensor compound and a pair of electrodes operatively oriented about the assembly of nanofibers to allow electrical current to pass from a first electrode in the pair of electrodes through the assembly of nanofibers and to a second electrode in the pair of electrodes.
FILED	Friday, December 02, 2016
APPL NO	15/368276
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Heterocyclic Compounds C07D 471/06 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 5/62 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 27/127 (20130101) G01N 33/0037 (20130101) G01N 33/0057 (20130101) Original (OR) Class
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11022610 — Integrated dual-modality microfluidic sensor for biomarker detection using lithographic plasmonic crystal

US 11022610	Dong et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Liang Dong (Ames, Iowa); Azahar Ali (Ames, Iowa); Shawana Tabassum (Ames, Iowa); Qiugu Wang (Ames, Iowa); Ratnesh Kumar (Ames, Iowa)
ABSTRACT	An integrated dual-modality microfluidic sensor chip and methods for using the same. In one form, the sensor comprises a patterned periodic array of nanoposts coated with a noble metal and graphene oxide (GO) to detect target biomarker molecules in a limited sample volume. The device generates both electrochemical and surface plasmon resonance (SPR) signals from a single sensing area of the metal-GO nanoposts. The metal-GO nanoposts are functionalized with specific receptor molecules, serving as a spatially well-defined nanostructured working electrode for electrochemical sensing, as well as a nanostructured plasmonic crystal for SPR-based sensing via the excitation of surface plasmon polaritons. The integrated dual-modality sensor offers higher sensitivity (through higher surface area and diffusions from nanoposts for electrochemical measurements), as well as the dynamic measurements of antigen-antibody bindings (through the SPR measurement), while operating simultaneously in a same sensing area using a same sample volume.
FILED	Monday, January 21, 2019
APPL NO	16/253104
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 2200/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/553 (20130101) G01N 27/3276 (20130101) G01N 27/3278 (20130101) G01N 33/531 (20130101) G01N 33/553 (20130101) Original (OR) Class G01N 33/5748 (20130101) G01N 2021/258 (20130101)
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11022654 — Universal driver systems and methods of operating the same

US 11022654	Wang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Tennessee Research Foundation (Knoxville, Tennessee); Keysight Technologies, Inc. (Santa Rosa, California)
ASSIGNEE(S)	UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); KEYSIGHT TECHNOLOGIES, INC. (Santa Rosa, California)
INVENTOR(S)	Fei Wang (Knoxville, Tennessee); Wen Zhang (Wuhan, China PRC); Bernhard Holzinger (Gaertringen, Germany)
ABSTRACT	A system includes a controller that is configured to generate a plurality of switch control signals; a plurality of electrical circuit elements, the plurality of electrical circuit elements being characterized by a plurality of impedances, respectively; a plurality of voltage sources; and a plurality of switches that are programmable to couple the plurality of electrical circuit elements to the plurality of voltage sources responsive to the plurality of switch control signals.
FILED	Thursday, March 12, 2020
APPL NO	16/817105
ART UNIT	2849 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/40 (20130101) Original (OR) Class G01R 31/2621 (20130101) G01R 31/2623 (20130101) G01R 31/2879 (20130101) G01R 31/31721 (20130101) G01R 31/31723 (20130101) G01R 31/31924 (20130101) G01R 31/31926 (20130101) Electric Digital Data Processing G06F 11/2733 (20130101) Pulse Technique H03K 17/693 (20130101)
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11023523 — Video content retrieval system

US 11023523	Hauptmann et al.
FUNDED BY	Department of Homeland Security (DHS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Alexander G. Hauptmann (Finleyville, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Alexander G. Hauptmann (Finleyville, Pennsylvania); Lu Jiang (Pittsburgh, Pennsylvania); Po-yao Huang (Pittsburgh, Pennsylvania)
ABSTRACT	This document describes a search retrieval system for automatically indexing data representing audio-visual recordings and for querying, responsive to a search query, that indexed data representing the audio-visual recordings. The search retrieval system defines weights for semantic features of an audio-visual recording and extracts, based on execution of a first set of rules, one or more semantic features. The system determines a weight for each of the one or more semantic features. A search engine searches nodes in the graph of the semantic features to identify one or more logical relationships for the one or more semantic features extracted. The weights for each of the one or more semantic features are adjusted based on the graph. The data is indexed in association with the one or more adjusted weights for the one or more semantic features, respectively.
FILED	Monday, October 24, 2016
APPL NO	15/769233
ART UNIT	2166 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/71 (20190101) Original (OR) Class G06F 16/78 (20190101) G06F 16/738 (20190101) G06F 16/7834 (20190101) G06F 16/7837 (20190101) G06F 16/7844 (20190101) Computer Systems Based on Specific Computational Models G06N 5/025 (20130101)
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11023594 — Locally private determination of heavy hitters

US 11023594	Nissim Kobliner et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Georgetown University (Washington, District of Columbia); President and Fellows of Harvard College (Cambridge, Massachusetts); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	Georgetown University (Washington, District of Columbia)
INVENTOR(S)	Yaacov Nissim Kobliner (Brookline, Massachusetts); Uri Stemmer (Cambridge, Massachusetts); Raef Bahi Youssef Bassily (San Diego, California); Abhradeep Guha Thakurta (Santa Cruz, California)
ABSTRACT	Technologies are disclosed for computing heavy hitter histograms using locally private randomization. Under this strategy, “agents” can each hold a “type” derived from a large dictionary. By performing an algorithm, an estimate of the distribution of data can be obtained. Two algorithms implement embodiments for performing methods involving differential privacy for one or more users, and usually are run in the local model. This means that information is collected from the agents with added noise to hide the agents' individual contributions to the histogram. The result is an accurate enough estimate of the histogram for commercial or other applications relating to the data collection of one or more agents. Specifically, the proposed algorithms improve on the performance (measured in computation and memory requirements at the server and the agent, as well as communication volume) of previously solutions.
FILED	Tuesday, May 22, 2018
APPL NO	15/986734
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/602 (20130101) Original (OR) Class G06F 21/6245 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0643 (20130101) H04L 2209/08 (20130101)
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11024047 — Cameras and depth estimation of images acquired in a distorting medium

US 11024047	Peng et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Yan-Tsung Peng (New Taipei, Taiwan); Pamela Cosman (La Jolla, California)
ABSTRACT	The invention provides a method for depth estimation in image or video obtained from a distorting medium. In the method, a pixel blurriness map is calculated. A rough depth map is then determined from the pixel blurriness map while assuming depth in a small local patch is uniform. The rough depth map is then refined. The method can be implemented in imaging systems, such as cameras or imaging processing computers, and the distorting medium can be an underwater medium, haze, fog, low lighting, or a sandstorm, for example. Preferred embodiments determined the blurriness map by calculating a difference between an original image and multi-scale Gaussian-filtered images to estimate the pixel blurriness map.
FILED	Thursday, September 15, 2016
APPL NO	15/759106
ART UNIT	2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/005 (20130101) G06T 5/20 (20130101) G06T 7/90 (20170101) G06T 7/571 (20170101) G06T 7/586 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) Pictorial Communication, e.g Television H04N 5/2252 (20130101) H04N 5/23229 (20130101)
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11024429 — Method, system and computer readable medium for adaptive and advisory control of diabetes

US 11024429	Patek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Science Foundation (NSF)
APPLICANT(S)	Stephen D. Patek (Charlottesville, Virginia); Boris P. Kovatchev (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	Stephen D. Patek (Charlottesville, Virginia); Boris P. Kovatchev (Charlottesville, Virginia)
ABSTRACT	An Adaptive Advisory Control (AA Control) interactive process involving algorithm-based assessment and communication of physiologic and behavioral parameters and patterns assists patients with diabetes with the optimization of their glycemic control. The method and system may uses all available sources of information about the patient; (i) EO Data (e.g. self-monitoring of blood glucose (SMBG) and CMG), (ii) Insulin Data (e.g. insulin pump log files or patient treatment records), and (iii) Patient Self Reporting Data (e.g. self treatment behaviors, meals, and exercise) to: retroactively assess the risk of hypoglycemia, retroactively assess risk-based reduction of insulin delivery, and then report to the patient how a risk-based insulin reduction system would have acted consistently to prevent hypoglycemia.
FILED	Sunday, August 26, 2012
APPL NO	14/241383
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0022 (20130101) A61B 5/486 (20130101) A61B 5/743 (20130101) A61B 5/1118 (20130101) A61B 5/4812 (20130101) A61B 5/4839 (20130101) A61B 5/4848 (20130101) A61B 5/4857 (20130101) A61B 5/4866 (20130101) A61B 5/7225 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) A61B 5/7282 (20130101) A61B 5/7475 (20130101) A61B 5/14532 (20130101) A61B 2505/07 (20130101) A61B 2560/0295 (20130101) A61B 2560/0475 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 5/16886 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 20/30 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) Original (OR) Class
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11024710 — Vertically oriented planar structures of transition metal chalcogenides for advanced electronic and optoelectronic systems

US 11024710	Robinson et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Joshua Alexander Robinson (Spring Mills, Pennsylvania); Rafael Vila (Sierra Vista, Arizona)
ABSTRACT	The present invention relates to methods for fabricating vertical homogenous and heterogeneous two-dimensional structures, the fabricated vertical two-dimensional structures, and methods of using the same. The methods demonstrated herein produce structures that are free standing and electrically isolated.
FILED	Friday, September 22, 2017
APPL NO	15/712561
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0259 (20130101) H01L 21/02376 (20130101) H01L 21/02378 (20130101) H01L 21/02381 (20130101) H01L 21/02565 (20130101) H01L 21/02568 (20130101) H01L 21/02612 (20130101) H01L 21/02664 (20130101) H01L 29/24 (20130101) H01L 29/045 (20130101) H01L 29/0665 (20130101) Original (OR) Class H01L 29/0669 (20130101) H01L 29/778 (20130101) H01L 29/785 (20130101) H01L 29/66795 (20130101)
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11024859 — High temperature humidification membranes

US 11024859	Chen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Dongmei Chen (Austin, Texas); Wei Li (Austin, Texas); Russell Borduin (Austin, Texas)
ABSTRACT	Membranes and methods of making and using the membranes are described herein. The membranes can include a foamed polymeric support and a plurality of inorganic particles disposed within the foamed polymeric support. The foamed polymeric support can contain a hydrophilic polymer such as polyethersulfone. The plurality of inorganic particles can include hydrophilic particles such as zeolite particles. In certain embodiments, the membrane can be used in humidifiers, such as those used in fuel cell systems. In some aspects, the membrane can be used for separating a fluid mixture comprising water. The membranes described herein are stable for high temperature applications.
FILED	Friday, February 03, 2017
APPL NO	15/424125
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 67/0079 (20130101) B01D 69/148 (20130101) B01D 71/028 (20130101) B01D 71/68 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/10 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/3453 (20130101) B29C 48/08 (20190201) B29C 67/202 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2069/00 (20130101) B29K 2071/00 (20130101) B29K 2075/00 (20130101) B29K 2077/00 (20130101) B29K 2081/06 (20130101) B29K 2105/16 (20130101) B29K 2105/041 (20130101) B29K 2503/04 (20130101) B29K 2995/0063 (20130101) B29K 2995/0092 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/755 (20130101) B29L 2031/3468 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04149 (20130101) Original (OR) Class H01M 2008/1095 (20130101)
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11025321 — Reconfigurable, bi-directional, multi-band front end for a hybrid beamforming transceiver

US 11025321	Paramesh et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S)	Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania)
ABSTRACT	Designs and techniques to enhance power-efficiency and incorporate new features in millimeter-wave MIMO transceivers are described. A new mechanism for built-in dual-band, per-element self-interference cancellation (SIC) is introduced to enable multi-antenna frequency-division duplex (FDD) and full-duplex (FD) operation. Additionally, several innovative circuit concepts are introduced, including low-loss wideband antenna interface design, dual-band power combining PA, dual-band RF-SIC design, and bi-directional MIMO signal path design.
FILED	Monday, February 03, 2020
APPL NO	16/780535
ART UNIT	2632 — Digital Communications
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/523 (20130101) H01Q 3/38 (20130101) H01Q 21/0025 (20130101) Transmission H04B 1/40 (20130101) H04B 7/0413 (20130101) H04B 7/0617 (20130101) Original (OR) Class
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11025519 — Systems, methods and computer-readable media for external non-intrusive packet delay measurement

US 11025519	Koral et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	AT and T Intellectual Property I, L.P. (Atlanta, Georgia)
ASSIGNEE(S)	AT and T Intellectual Property I, L.P. (Atlanta, Georgia); The Trustees Of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Yaron Koral (Cherry Hill, New Jersey); Tuan Duong (Eatontown, New Jersey); Steven A. Monetti (Mountain Lakes, New Jersey); Tzuu-Yi Wang (Newtown, Pennsylvania); Simon Tse (Holmdel, New Jersey); Shir Landau Feibish (Princeton, New Jersey); Jennifer Rexford (Princeton, New Jersey); Xiaoqi Chen (Princeton, New Jersey)
ABSTRACT	Methods, systems, and computer-readable media for measuring packet delays are provided. An input port of a network device is tapped to duplicate an input packet stream having a first packet. An output port of the network device is tapped to duplicate an output packet stream including the first packet. The duplicated input packet stream and the duplicated output packet stream is transmitted to a programmable device. The first packet in the first input packet stream is matched to the first packet in the first output packet stream. An arrival time and a departure time for the first packet is measured. The difference between the departure time of the first packet and the arrival time of the first packet is determined and the value is reported to an external collector.
FILED	Wednesday, April 10, 2019
APPL NO	16/380484
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 43/12 (20130101) H04L 43/0858 (20130101) Original (OR) Class
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11025600 — System for de-duplicating network coded distributed storage and related techniques

US 11025600	Medard et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Muriel Medard (Belmont, Massachusetts); Prakash Narayana Moorthy (Framingham, Massachusetts); Vitaly Abdrashitov (Somerville, Massachusetts)
ABSTRACT	Methods for encoding a file and de-duplicating a coded packet of the file are presented. The encoding method includes: identifying a file to be stored; encoding the file to generate a plurality of coded packets; generating a hash code associated with the file; distributing the plurality of coded packets to a plurality of storage nodes; and storing the hash code associated with the file in a hash server. The de-duplicating method includes: receiving a coded packet at a storage node; retrieving a hash code, from the hash server, corresponding to the coded packet; determining whether the coded packet has been stored in the storage node based upon the hash code; in response to determination that the coded packet has being stored, discarding the coded packet; and in response to determination that the coded packet has not being stored, storing the coded packet in the storage node.
FILED	Thursday, November 08, 2018
APPL NO	16/184272
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 16/256 (20190101) G06F 16/1827 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) H04L 61/103 (20130101) H04L 61/2007 (20130101) H04L 61/6086 (20130101) H04L 63/0471 (20130101) Original (OR) Class
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Department of Agriculture (USDA)

11019776 — Compositions and methods for modulating immunity in plants

US 11019776	Klessig et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Boyce Thompson Institute for Plant Research, Inc. (Ithaca, New York)
ASSIGNEE(S)	BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York)
INVENTOR(S)	Daniel Klessig (Dryden, New York); Frank Schroeder (Ithaca, New York); Patricia Manosalva (Ithaca, New York)
ABSTRACT	Compositions and methods for enhancing disease resistance in plants are disclosed.
FILED	Tuesday, October 16, 2018
APPL NO	16/161252
ART UNIT	1663 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 3/04 (20130101) Original (OR) Class Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/16 (20130101) A01N 43/38 (20130101) A01N 63/10 (20200101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8281 (20130101) C12N 15/8282 (20130101) C12N 15/8283 (20130101) C12N 15/8285 (20130101)
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11019809 — Porcine reproductive and respiratory syndrome virus resistant animals

US 11019809	Prather et al.
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS)
APPLICANT(S)	The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Randall S. Prather (Rocheport, Missouri); Kevin D. Wells (Columbia, Missouri); Kristin M. Whitworth (Columbia, Missouri)
ABSTRACT	The present invention generally relates to genetically modified swine wherein at least one allele of a SIGLEC1 gene has been inactivated and/or at least one allele of a CD163 gene has been inactivated. Genetically modified swine having both alleles of the SIGLEC1 gene and/or both alleles CD163 gene inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSV). Methods for producing such transgenic swine are also provided.
FILED	Friday, August 30, 2019
APPL NO	16/556878
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/108 (20130101) A01K 2267/02 (20130101) Peptides C07K 14/7056 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101)
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11021760 — Fungal chromosome-end knockoff strategy

US 11021760	Schardl et al.
FUNDED BY	Department of Agriculture (USDA) Agriculture and Food Research Initiative (AFRI) National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI)
APPLICANT(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S)	Christopher L. Schardl (Lexington, Kentucky); Simona Florea (Lexington, Kentucky); Mark L. Farman (Lexington, Kentucky)
ABSTRACT	Non-toxigenic fungal strains, and methods of making and use thereof, are provided and have utility as endophytes in forage crops, and as strains that can outcompete toxigenic strains in forage and food crops.
FILED	Thursday, June 01, 2017
APPL NO	15/610860
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) Original (OR) Class
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11022529 — Sizable tunable enrichment platform for capturing nano particles in a fluid

US 11022529	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) United States Air Force (USAF) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI) Department of Agriculture (USDA)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Siyang Zheng (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Yin-Ting Yeh (State College, Pennsylvania); Yi Tang (State College, Pennsylvania); Huaguang Lu (State College, Pennsylvania); Nestor Perea Lopez (State College, Pennsylvania); Yiqiu Xia (State College, Pennsylvania)
ABSTRACT	The invention provides enrichment platform devices for size-based capture of particles in solution. The enrichment platform device is useful for label-free capture of any particle. The invention relates to enrichment platform devices using nanowires and vertically aligned carbon nanotubes. The invention provides methods for making the enrichment platform devices. The invention provides methods for using the enrichment platform devices for filtering particles, capturing particles, concentrating particles, and releasing viable particles.
FILED	Friday, February 07, 2020
APPL NO	16/784507
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/12 (20130101) B01L 2300/041 (20130101) B01L 2300/0681 (20130101) B01L 2300/0896 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) Original (OR) Class G01N 1/4077 (20130101) G01N 33/552 (20130101) G01N 33/54346 (20130101) G01N 33/56983 (20130101) G01N 2001/4088 (20130101) G01N 2333/11 (20130101)
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11022672 — Mobile emergency perimeter system and method

US 11022672	Chartier et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S)	Eric Chartier (St. Louis Park, Minnesota); Paul C. Davis (Saratoga, California); Ryan L Hagelstrom (Chaska, Minnesota); Ian J. McLinden (Minneapolis, Minnesota); Douglas Sweet (Sunnyvale, California)
ABSTRACT	A computer-implemented method for establishing and controlling a mobile perimeter and for determining a geographic location of an RF emitting source at or within the mobile perimeter includes receiving from RF sensors in a network, processed RF emissions from the source collected at RF sensors. The RF emissions follow a wireless protocol and include frames encoding RF emitting source identification information. The method further includes extracting RF emitting source identification information from one or more of the frames, processing the source identification information to identify the RF emitting source, and classifying the RF emitting source by one or more of UAS type, UAS capabilities, and UAS model. The method also includes receiving from the RF sensors, a geographic location of each RF sensor and a time of arrival (TOA) of the RF emissions at the RF sensor; and executing a multilateration process to estimate a geographic location of the RF emitting source.
FILED	Friday, December 20, 2019
APPL NO	16/723980
ART UNIT	2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) Original (OR) Class G01S 5/0018 (20130101) G01S 5/021 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) H04L 67/18 (20130101) Wireless Communication Networks H04W 4/021 (20130101) H04W 4/40 (20180201) H04W 84/18 (20130101)
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PP033116 — Lantana camara plant named ‘UF-1013-1’

US PP33116	Deng
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS) Tropical and Subtropical Agricultural Research (TSTAR) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Florida Foundation Seed Producers, Inc. (Marianna, Florida)
ASSIGNEE(S)	Florida Foundation Seed Producers, Inc. (Marianna, Florida)
INVENTOR(S)	Zhanao Deng (Riverview, Florida)
ABSTRACT	A new and distinct cultivar of Lantana camara plant named ‘UF-1013-1’, characterized by its moderate vigor, mounding growth habit, dense branches, round plant form and canopy, free flowering, bright yellow and red flowers, no to little fruiting, no to few seeds, a very high level of female infertility, a very low level of pollen stainability and viability, a very high level of male infertility, lack of hybridization with Lantana depressa, triploidy and a unique combination of DNA marker alleles, is disclosed.
FILED	Wednesday, December 02, 2020
APPL NO	16/974252
ART UNIT	1661 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/86 (20180501) Original (OR) Class
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National Aeronautics and Space Administration (NASA)

11019862 — Grasp assist system with triple Brummel soft anchor

US 11019862	McBryan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Emily R. McBryan (Houston, Texas); Jonathan M. Rogers (League City, Texas); Benjamin J. Peters (Houston, Texas); Evan Laske (Houston, Texas)
ABSTRACT	A grasp assist system includes a glove, finger saddles attached to a respective glove finger, one or more tendon actuators, and artificial tendons. The saddles have a rectangular body partially circumscribing a respective glove finger. Each saddle includes end lobes at opposite distal ends of the body. A first end of each tendon is secured to one of the tendon actuators. A second end forms a triple Brummel loop defining a main loop and two anchor loops. The anchor loops are disposed around the lobes. The saddles may form a rounded, double-headed arrow shape that is at least double the thickness of the body. The finger saddles are anisotropic, with different bending strengths depending on the axis, and may be constructed of thermoplastic polyurethane-coated nylon. Flexion and/or contact sensors and a controller, may be used. A method of connecting the tendon actuator to the finger is also disclosed.
FILED	Thursday, April 05, 2018
APPL NO	15/946519
ART UNIT	3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Outerwear; Protective Garments; Accessories A41D 19/0006 (20130101) A41D 19/015 (20130101) A41D 19/0024 (20130101) Original (OR) Class A41D 19/0044 (20130101) A41D 2500/50 (20130101) A41D 2600/20 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 25/08 (20130101) B32B 25/20 (20130101) B32B 27/08 (20130101) B32B 27/36 (20130101) B32B 27/322 (20130101) B32B 2307/558 (20130101) B32B 2307/3065 (20130101) B32B 2307/7265 (20130101)
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11021972 — Variable pitch blade holder for gas turbine engine

US 11021972	Bailey
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S)	Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
INVENTOR(S)	Patrick Bailey (Lebanon, Indiana)
ABSTRACT	A variable pitch blade holder for use with a gas turbine engine. The variable pitch blade holder is configured to retain a blade and to rotate about a center axis with the blade during operation of the gas turbine engine. The blade holder is adapted to rotate about a pitch change axis to vary a pitch of the blade.
FILED	Tuesday, August 14, 2018
APPL NO	16/103407
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/282 (20130101) F01D 5/3007 (20130101) Original (OR) Class F01D 7/00 (20130101) Non-positive-displacement Pumps F04D 29/322 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/20 (20130101) F05D 2240/80 (20130101) F05D 2260/941 (20130101) F05D 2300/603 (20130101)
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11023249 — First stage bootloader (FSBL)

US 11023249	Corekin
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Jennifer A. S. Corekin (Odenton, Maryland)
ABSTRACT	The present invention relates to a method of reading images using redundant copies and recovery mechanisms to produce valid images, including: reading an OS boot table from a default location in at least one flash memory to at least one DDR SDRAM of a printed circuit board, using at least one processor connected to at least one FPGA; wherein the boot table describes where to find an OS image and a RAM filesystem image in the flash memory; reading a RAM filesystem image from the flash memory into the DDR SDRAM; and validating the boot table and the RAM filesystem image by checking them for corruption using header information and cyclic redundancy check methods; wherein when at least one of the OS image or the RAM filesystem image is corrupt, a valid image can be compiled using valid sections of each of the OS image or the RAM filesystem image.
FILED	Wednesday, September 26, 2018
APPL NO	16/142187
ART UNIT	2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 9/4401 (20130101) Original (OR) Class G06F 11/1004 (20130101) G06F 11/1417 (20130101) G06F 16/18 (20190101) G06F 16/1734 (20190101) G06F 21/64 (20130101) G06F 21/575 (20130101)
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11024181 — Systems and methods for generating avionic displays including forecast overpressure event symbology

US 11024181	Suddreth et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina)
INVENTOR(S)	John G. Suddreth (Cave Creek, Arizona); Marisela Mendez Tapia (San Jose, California); Jerry Ball (Peoria, Arizona); Mark Giddings (Mesa, Arizona)
ABSTRACT	Avionic display systems and methods are provided for generating avionic displays, which include symbology and other graphics pertaining to forecast overpressure events, which are forecast to occur during supersonic aircraft flight. In various embodiments, the avionic display system includes a display device on which an avionic display is produced. A controller architecture is operably coupled to the display device. Storage media contains computer-readable code or instructions that, when executed by the controller architecture, cause the avionic display system to determine whether an overpressure event is forecast to occur due to the predicted future occurrence of a sonic boom, which has a magnitude exceeding a boom tolerance threshold. When the controller architecture determines that an overpressure event is forecast to occur, the avionic display system further generates symbology on the avionic display indicative of or visually signifying the forecast overpressure event.
FILED	Tuesday, September 24, 2019
APPL NO	16/580626
ART UNIT	2685 — Selective Communication
CURRENT CPC	Aeroplanes; Helicopters B64C 30/00 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) B64D 45/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/00 (20130101) G01H 5/00 (20130101) G01H 17/00 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0017 (20130101) Original (OR) Class G08G 5/0021 (20130101) G08G 5/0052 (20130101) G08G 5/0069 (20130101) G08G 5/0086 (20130101) G08G 5/0091 (20130101)
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11024876 — Composite membrane comprising solid electrolyte, method of making said composite membrane, and electrochemical cell comprising said composite membrane

US 11024876	Xu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Army (DOA) United States Army (USA) National Aeronautics and Space Administration (NASA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Giner, Inc. (Newton, Massachusetts)
ASSIGNEE(S)	GINER, INC. (Newton, Massachusetts)
INVENTOR(S)	Hui Xu (Acton, Massachusetts); Jarrod D. Milshtein (Cambridge, Massachusetts); Katherine Harrison (Arlington, Massachusetts); Mario Moreira (Hudson, Massachusetts); Brian Rasimick (Boston, Massachusetts)
ABSTRACT	A composite membrane that is suitable for use in an electrochemical cell, an electrochemical cell including the composite membrane, and a method of making the composite membrane. In one embodiment, the composite membrane includes a porous support and a solid electrolyte. The porous support is a unitary structure made of a polymer that is non-conductive to ions. The porous support is shaped to include a plurality of straight-through pores. The solid electrolyte has alkali ion conductivity and preferably completely fills at least some of the pores of the porous support. A variety of techniques may be used to load the solid electrolyte into the pores. According to one technique, the solid electrolyte is melted and then poured into the pores of the porous support. Upon cooling, the electrolyte re-solidifies, forming a monolithic structure within the pores of the porous support.
FILED	Wednesday, November 01, 2017
APPL NO	15/801118
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/02 (20130101) H01M 4/13 (20130101) H01M 10/052 (20130101) H01M 10/0486 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101)
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11026331 — SpaceCube V3.0 single-board computer

US 11026331	Flatley et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Thomas Flatley (Greenbelt, Maryland); Alessandro Giest (Greenbelt, Maryland); David Petrick (Greenbelt, Maryland); Gary Crum (Greenbelt, Maryland); Milton Davis (Greenbelt, Maryland)
ABSTRACT	A single-board computer system radiation hardened for space flight includes a printed circuit board (PCB) having a top side and bottom side; a reconfigurable field programmable gate array (FPGA) processor device a connector disposed on the top side; a plurality of peripheral components mounted on the bottom side, wherein AC coupling capacitors are configured to select routing between the first FPGA and the second FPGA. An expansion card plug attaches to a connector on the bottom of the PCB and a frame is mounted to the PCB.
FILED	Friday, September 27, 2019
APPL NO	16/586210
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 11/1076 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/18 (20130101) Original (OR) Class H05K 1/113 (20130101) H05K 2201/09309 (20130101) H05K 2201/09509 (20130101) H05K 2201/10015 (20130101) H05K 2201/10159 (20130101) H05K 2201/10189 (20130101) H05K 2201/10212 (20130101) H05K 2201/10545 (20130101)
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Department of Homeland Security (DHS)

11022555 — Methods and compositions for rapid multiplex application of STR loci

US 11022555	Schumm et al.
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	ANDE Corporation (Waltham, Massachusetts)
ASSIGNEE(S)	ANDE CORPORATION (Waltham, Massachusetts)
INVENTOR(S)	James W. Schumm (Lakewood Ranch, Florida); Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts)
ABSTRACT	Provided are methods for multiplex polymerase chain reaction (PCR) amplification of short tandem repeat (STR) loci that can be used to rapidly generate a highly specific STR profile from target nucleic acids. The resulting STR profiles are useful for human identification purposes in law enforcement, homeland security, military, intelligence, and paternity testing applications.
FILED	Monday, October 16, 2017
APPL NO	15/784929
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class
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11022592 — Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor

US 11022592	Zang et al.
FUNDED BY	Department of Homeland Security (DHS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Ling Zang (Salt Lake City, Utah); Na Wu (Salt Lake City, Utah); Paul Slattum (Salt Lake City, Utah)
ABSTRACT	A chemiresistive vapor sensor compound for detecting target vapors can comprise a perylene-tetracarboxylic diimide (PTCDI) core according to structure (I): where R can be a morphology control group or -A′-D′, A and A′ can be independently a linking group, D and D′ can be independently a strong electron donor which transfers electrons to the PTCDI core sufficient to form an anionic PTCDI radical of the PTCDI core, and R1 to R8 can be independently a side group. A chemiresistive vapor sensor for detection of a target compound can comprise an assembly of nanofibers formed of the chemiresistive sensor compound and a pair of electrodes operatively oriented about the assembly of nanofibers to allow electrical current to pass from a first electrode in the pair of electrodes through the assembly of nanofibers and to a second electrode in the pair of electrodes.
FILED	Friday, December 02, 2016
APPL NO	15/368276
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Heterocyclic Compounds C07D 471/06 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 5/62 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 27/127 (20130101) G01N 33/0037 (20130101) G01N 33/0057 (20130101) Original (OR) Class
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11023523 — Video content retrieval system

US 11023523	Hauptmann et al.
FUNDED BY	Department of Homeland Security (DHS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Alexander G. Hauptmann (Finleyville, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Alexander G. Hauptmann (Finleyville, Pennsylvania); Lu Jiang (Pittsburgh, Pennsylvania); Po-yao Huang (Pittsburgh, Pennsylvania)
ABSTRACT	This document describes a search retrieval system for automatically indexing data representing audio-visual recordings and for querying, responsive to a search query, that indexed data representing the audio-visual recordings. The search retrieval system defines weights for semantic features of an audio-visual recording and extracts, based on execution of a first set of rules, one or more semantic features. The system determines a weight for each of the one or more semantic features. A search engine searches nodes in the graph of the semantic features to identify one or more logical relationships for the one or more semantic features extracted. The weights for each of the one or more semantic features are adjusted based on the graph. The data is indexed in association with the one or more adjusted weights for the one or more semantic features, respectively.
FILED	Monday, October 24, 2016
APPL NO	15/769233
ART UNIT	2166 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 16/71 (20190101) Original (OR) Class G06F 16/78 (20190101) G06F 16/738 (20190101) G06F 16/7834 (20190101) G06F 16/7837 (20190101) G06F 16/7844 (20190101) Computer Systems Based on Specific Computational Models G06N 5/025 (20130101)
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11023569 — Secure re-enrollment of biometric templates using functional encryption

US 11023569	Eldefrawy et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Karim Eldefrawy (Palo Alto, California); Tancrede Lepoint (Jersey City, New Jersey)
ABSTRACT	An example computing device includes a functional encryption unit configured to generate a master secret key and public key; apply functional encryption using the public key to biometric information of a user to produce functionally encrypted biometric information, the functional encryption is based on an encryption function that encodes the biometric information, a computation engine configured to perform re-enrollment by at least one of 1) retrieving a pre-generated function key from a memory, or 2) retrieving a dynamically generated function key from the one or more storage nodes that can be inaccessible during user authentication, the function key dynamically generated using the master secret key, and applying, using the function key and functionally encrypted biometric information, a decryption operation to generate new helper data, wherein the new helper data is generated as an evaluation of a cryptographic function during the decryption operation without the need to decrypt the biometric information.
FILED	Tuesday, May 29, 2018
APPL NO	15/991037
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00926 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0861 (20130101) H04L 9/0894 (20130101)
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Small Business Administration (SBA)

11020494 — Animal models for nonalcoholic fatty liver disease

US 11020494	Peterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	CROWN BIOSCIENCE INC. (TAICANG) (Taicang, China PRC)
ASSIGNEE(S)	CROWN BIOSCIENCE INC. (TAICANG) (Jiangsu, China PRC)
INVENTOR(S)	Richard Peterson (Indianapolis, Indiana); Charles Van Jackson (Greenfield, Indiana); Gao Sun (Shanghai, China PRC); Guodong Zhang (Taicang, China PRC); Yixin (Jim) Wang (Lafayette, California)
ABSTRACT	The present disclosure provides non-human animal models of non-alcoholic fatty liver disease (NAFLD). Also provided are methods for producing the non-human animal models and uses of the non-human animal models to screen and evaluate agents for treating or preventing NAFLD.
FILED	Thursday, June 21, 2018
APPL NO	16/013953
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) A01K 2207/25 (20130101) A01K 2227/105 (20130101) A01K 2267/035 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class
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11022501 — Apparatus and method for measuring temperature of batteries and internal battery components

US 11022501	Hsieh et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Feasible, Inc. (Berkeley, California)
ASSIGNEE(S)	Feasible, Inc. (Berkeley, California)
INVENTOR(S)	Andrew Gaheem Hsieh (Berkeley, California); Barry James Van Tassell (El Cerrito, California); Daniel Artemis Steingart (Princeton, New Jersey); Shaurjo Biswas (El Cerrito, California); Robert Charles Mohr (Berkeley, California)
ABSTRACT	Systems and methods for measuring temperature characteristics of a battery include one or more transducers coupled to the battery for transmitting and/or receiving sound waves through at least a portion of the battery. A temperature measurement unit is provided to determine a time-of-flight of sound waves through at least the portion of the battery based on transmitted and received sound waves through at least the portion of the battery, and to determine temperature characteristics of at least the portion of the battery based on the time-of-flight.
FILED	Friday, October 11, 2019
APPL NO	16/599562
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 31/382 (20190101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/486 (20130101)
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11022555 — Methods and compositions for rapid multiplex application of STR loci

US 11022555	Schumm et al.
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	ANDE Corporation (Waltham, Massachusetts)
ASSIGNEE(S)	ANDE CORPORATION (Waltham, Massachusetts)
INVENTOR(S)	James W. Schumm (Lakewood Ranch, Florida); Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts)
ABSTRACT	Provided are methods for multiplex polymerase chain reaction (PCR) amplification of short tandem repeat (STR) loci that can be used to rapidly generate a highly specific STR profile from target nucleic acids. The resulting STR profiles are useful for human identification purposes in law enforcement, homeland security, military, intelligence, and paternity testing applications.
FILED	Monday, October 16, 2017
APPL NO	15/784929
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class
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11024876 — Composite membrane comprising solid electrolyte, method of making said composite membrane, and electrochemical cell comprising said composite membrane

US 11024876	Xu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Army (DOA) United States Army (USA) National Aeronautics and Space Administration (NASA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Giner, Inc. (Newton, Massachusetts)
ASSIGNEE(S)	GINER, INC. (Newton, Massachusetts)
INVENTOR(S)	Hui Xu (Acton, Massachusetts); Jarrod D. Milshtein (Cambridge, Massachusetts); Katherine Harrison (Arlington, Massachusetts); Mario Moreira (Hudson, Massachusetts); Brian Rasimick (Boston, Massachusetts)
ABSTRACT	A composite membrane that is suitable for use in an electrochemical cell, an electrochemical cell including the composite membrane, and a method of making the composite membrane. In one embodiment, the composite membrane includes a porous support and a solid electrolyte. The porous support is a unitary structure made of a polymer that is non-conductive to ions. The porous support is shaped to include a plurality of straight-through pores. The solid electrolyte has alkali ion conductivity and preferably completely fills at least some of the pores of the porous support. A variety of techniques may be used to load the solid electrolyte into the pores. According to one technique, the solid electrolyte is melted and then poured into the pores of the porous support. Upon cooling, the electrolyte re-solidifies, forming a monolithic structure within the pores of the porous support.
FILED	Wednesday, November 01, 2017
APPL NO	15/801118
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/02 (20130101) H01M 4/13 (20130101) H01M 10/052 (20130101) H01M 10/0486 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101)
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National Security Agency (NSA)

11023275 — Technologies for queue management by a host fabric interface

US 11023275	Dinan et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts); Timo Schneider (Hudson, Massachusetts)
ABSTRACT	Technologies for managing a queue on a compute device are disclosed. In the illustrative embodiment, the queue is managed by a host fabric interface of the compute device. Queue operations such as enqueuing data onto the queue and dequeuing data from the queue may be requested by remote compute devices by sending queue operations which may be processed by the host fabric interface. The host fabric interface may, in some embodiments, fully manage the queue without any assistance from the processor of the compute device. In other embodiments, the processor of the compute device may be responsible for certain tasks, such as garbage collection.
FILED	Thursday, February 09, 2017
APPL NO	15/428282
ART UNIT	2195 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/46 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 9/5016 (20130101)
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11023840 — Scenario planning and risk management

US 11023840	Chang et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Yuan-Chi Chang (Armonk, New York); Mark D. Feblowitz (Winchester, Massachusetts); Nagui Halim (Yorktown Heights, New York); Stuart S. Horn (Southbury, Connecticut); Edward J. Pring (Yorktown Heights, New York); Anton V. Riabov (Ann Arbor, Michigan); Edward W. Shay (White Plains, New York); Shirin Sohrabi Araghi (Port Chester, New York); Deepak S. Turaga (Elmsford, New York); Octavian Udrea (Ossining, New York); Fang Yuan (Chappaqua, New York); Peter Zimmer (Danbury, Connecticut)
ABSTRACT	Techniques for scenario planning are provided. In one example, a computer-implemented method can comprise analyzing, by a device operatively coupled to a processor, content using a topic model. The content can be associated with a defined source and is related to one or more current events. The computer-implemented method can also comprise determining, by the device, one or more portions of the analyzed content that are relevant to one or more key risk drivers using a risk driver model. The computer-implemented method can also comprise aggregating, by the device, the determined one or more portions into one or more emerging storylines based on values of one or more attributes of the topic model.
FILED	Friday, January 27, 2017
APPL NO	15/418377
ART UNIT	3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Electric Digital Data Processing G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0635 (20130101) Original (OR) Class
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11026351 — Computing apparatus with closed cooling loop

US 11026351	Kulkarni et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Devdatta P. Kulkarni (Olympia, Washington); Richard J. Dischler (Bolton, Massachusetts)
ABSTRACT	The present disclosure describes embodiments of apparatuses and methods related to a computing apparatus with a closed cooling loop thermally coupled to one or more processors disposed on a circuit board of the computing apparatus. The closed cooling loop circulates a dielectric fluid to absorb heat from the processor. A portion of the dielectric fluid is evaporated from the processor heat absorbed by the dielectric fluid. A heat exchanger is coupled to the circuit board and thermally coupled to the closed cooling loop. The heat exchanger is to include a coolant flow to remove heat from the dielectric fluid circulated through the portion of the closed cooling loop thermally coupled to the heat exchanger. A vapor portion of the dielectric fluid is condensed from the heat removed by the coolant flow. Other embodiments may be described and/or claimed.
FILED	Friday, September 25, 2015
APPL NO	15/754957
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 1/0203 (20130101) H05K 7/20327 (20130101) H05K 7/20809 (20130101) Original (OR) Class H05K 7/20818 (20130101) H05K 2201/064 (20130101)
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Department of Commerce (DOC)

11022538 — Quantum flow cytometer

US 11022538	Polyakov et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S)	GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S)	Sergey V. Polyakov (Gaithersburg, Maryland); Ivan A. Burenkov (Germantown, Maryland); Yu-Hsiang Cheng (North Brunswick, New Jersey)
ABSTRACT	A quantum flow cytometer detects an analyte with photon-number statistics and includes: a flow cytometer that receives a pump light, an analyte and produces scattered light from the analyte; an intensity interferometer that includes a beam splitter and receives the scattered light; splits the scattered light; and single photon detectors that receive the scattered light, such that the beam splitter and the single photon detectors provide photon number statistics that detects the analyte. A process for detecting the analyte with photon-number statistics includes: receiving the pump light; producing, by the analyte, scattered light from scattering the pump light; splitting the scattered light into first scattered light and second scattered light; detecting, by single photon detectors, the first scattered light and second scattered light; producing, by the single photon detectors, detection signals; and subjecting the detection signals to an analyzer to detect the analyte by photon number statistics.
FILED	Wednesday, May 15, 2019
APPL NO	16/413078
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 2015/1454 (20130101)
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11024841 — Template electrode structures for depositing active materials

US 11024841	Loveness et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Amprius, Inc. (Sunnyvale, California)
ASSIGNEE(S)	Amprius, Inc. (Fremont, California)
INVENTOR(S)	Ghyrn E. Loveness (Mountain View, California); William S. Delhagen (San Francisco, California); Rainer Fasching (Mill Valley, California); Song Han (Foster City, California); Zuqin Liu (Sunnyvale, California)
ABSTRACT	Provided are examples of electrochemically active electrode materials, electrodes using such materials, and methods of manufacturing such electrodes. Electrochemically active electrode materials may include a high surface area template containing a metal silicide and a layer of high capacity active material deposited over the template. The template may serve as a mechanical support for the active material and/or an electrical conductor between the active material and, for example, a substrate. Due to the high surface area of the template, even a thin layer of the active material can provide sufficient active material loading and corresponding battery capacity. As such, a thickness of the layer may be maintained below the fracture threshold of the active material used and preserve its structural integrity during battery cycling.
FILED	Thursday, January 31, 2019
APPL NO	16/264456
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/58 (20130101) H01M 4/66 (20130101) H01M 4/75 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/0428 (20130101) H01M 4/587 (20130101) H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115) Y10T 29/49115 (20150115)
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Classified Government Agency

11025358 — Method of adaptively mitigating common template multi-channel wireless interference

US 11025358	Beaudeau
FUNDED BY	Classified Government Agency
APPLICANT(S)	BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Jonathan P. Beaudeau (Littleton, Massachusetts)
ABSTRACT	A method of mitigating interference in a wireless signal of interest (SOI) received on an active frequency channel due to a common template multi-channel jamming attack includes selecting at least one reference channel from among a plurality of monitored frequency channels in which correlated jamming patterns are present without the SOI. The method further includes generating a plurality of weights according to data obtained from the active and reference channels, and applying an adaptive digital filter to the active channel according to the generated weights. The monitored frequency channels can be centered about the active frequency channel. The selection of reference channels can be varied and optimized. The data from each reference channel can be used to create a single virtual antenna tap or a plurality thereof. Assignment of the active channel can be time-varied to match a hopping pattern of a frequency hopping SOI.
FILED	Monday, April 20, 2020
APPL NO	16/852631
ART UNIT	2633 — Digital Communications
CURRENT CPC	Transmission H04B 1/28 (20130101) H04B 1/123 (20130101) H04B 1/525 (20130101) H04B 1/713 (20130101) H04B 1/1036 (20130101) Multiplex Communication H04J 11/0036 (20130101) Original (OR) Class
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Department of Veterans Affairs (DVA)

11020510 — Muscle cell patches and uses therefor

US 11020510	Lancaster et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Jordan J. Lancaster (Tucson, Arizona); Steven Goldman (Tucson, Arizona)
ABSTRACT	Disclosed herein are contractile cell constructs, methods for using them to treat disease, and methods for making them.
FILED	Thursday, December 20, 2018
APPL NO	16/228017
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 38/2292 (20130101) A61K 38/2292 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/367 (20130101) A61L 27/3826 (20130101) Original (OR) Class A61L 27/3873 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) C12N 2506/1315 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101)
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Office of the Director of National Intelligence (ODNI)

11023711 — All-in-one convolutional neural network for face analysis

US 11023711	Ranjan et al.
FUNDED BY	Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S)	Rajeev Ranjan (College Park, Maryland); Swaminathan Sankaranarayanan (University Park, Maryland); Carlos Castillo (Silver Spring, Maryland); Ramalingam Chellappa (Potomac, Maryland)
ABSTRACT	Various facial recognition systems may benefit from appropriate use of computer systems. For example, certain face analysis systems may benefit from an all-in-one convolutional neural network that has been appropriately configured. A method can include obtaining an image of a face. The method can also include processing the image of the face using a first set of convolutional network layers configured to perform subject-independent tasks. The method can further include subsequently processing the image of the face using a second set of convolutional network layers configured to perform subject-dependent tasks. The second set of convolutional network layers can be integrated with the first set of convolutional network layers to form a single convolutional neural network. The method can additionally include outputting facial image detection results based on the processing and subsequent processing.
FILED	Tuesday, October 10, 2017
APPL NO	16/340859
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00228 (20130101) G06K 9/00288 (20130101) Original (OR) Class G06K 9/00302 (20130101) G06K 9/4628 (20130101) G06K 9/6262 (20130101) G06K 9/6267 (20130101)
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Government Rights Acknowledged

11021962 — Turbulent air reducer for a gas turbine engine

US 11021962	Tatman et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Neil L. Tatman (Brentwood, New Hampshire); Nathan K. Galle (Portland, Maine); Richard K. Hayford (Cape Neddick, Maine)
ABSTRACT	A turbulent air reducer assembly for a gas turbine engine includes a windage cover attached to a first standoff and a second standoff, the windage cover tuned to a particular vibration response. A method of managing air within a turbine of a gas turbine engine includes reducing turbulence from a multiple of recesses within a tangential on-board injector with a turbulent air reducer assembly within each of the multiple of recesses, the turbulent air reducer assembly tuned to a particular vibration response from a turbine rotor.
FILED	Wednesday, August 22, 2018
APPL NO	16/108763
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/10 (20130101) F01D 5/085 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2260/31 (20130101) F05D 2260/96 (20130101)
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11021985 — Non-contact seal with resilient biasing element(s)

US 11021985	D'Ambruoso
FUNDED BY
APPLICANT(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Tara L. D'Ambruoso (Oxford, Connecticut)
ABSTRACT	A seal device includes a plurality of seal shoes, a seal base, a plurality of spring elements and a resilient biasing element. The seal shoes are arranged around an axis. The seal base circumscribes the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes and the seal base. A first of the spring elements includes a first mount, a second mount and a spring beam. The first mount is connected to a first of the seal shoes. The second mount is connected to the seal base. The spring beam connects the first mount to the second mount. The resilient biasing element is radially between and engaged with first and second components of the seal device, where the first component is configured as or otherwise includes the first mount or the second mount.
FILED	Monday, January 14, 2019
APPL NO	16/246748
ART UNIT	3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) F01D 11/003 (20130101) F01D 11/025 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/10 (20130101) F05D 2240/20 (20130101) F05D 2240/55 (20130101) F05D 2260/38 (20130101) F05D 2260/52 (20130101) Pistons; Cylinders; Sealings F16J 15/442 (20130101) F16J 15/447 (20130101) F16J 15/3452 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11021990 — Shroud sealing for a gas turbine engine

US 11021990	Filippi
FUNDED BY
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Sergio Filippi (Montgomery, Ohio)
ABSTRACT	A shroud assembly for gas turbine engine defining an axial direction, a radial direction, and a circumferential direction includes a shroud segment extending substantially along the circumferential direction and including a forward wall and an aft wall spaced along the axial direction from one another and defining a cavity therebetween; and a hanger assembly including a first attachment member and a seal member, the first attachment member attached to one of the forward wall or the aft wall of the shroud segment, and the seal member positioned within the cavity and interference fit against the other of the forward wall or the aft wall of the shroud segment.
FILED	Wednesday, December 19, 2018
APPL NO	16/225371
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/122 (20130101) Original (OR) Class F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2240/14 (20130101) F05D 2300/6033 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11022144 — Diffuser case assembly

US 11022144	Hough et al.
FUNDED BY
APPLICANT(S)	United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S)	Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Matthew Andrew Hough (West Simsbury, Connecticut); John S. Tu (Agawam, Massachusetts); Stephen C. Harmon (East Hampton, Connecticut); Paul F. Croteau (Columbia, Connecticut); Russell B. Hanson (Jupiter, Florida); Joshua C. Rathgeb (Glastonbury, Connecticut)
ABSTRACT	A diffuser case assembly for a gas turbine engine includes a fairing disposed circumferentially about a longitudinal axis. The fairing defines a plurality of passages circumferentially spaced apart and forming at least a portion of a fluid path between a compressor and a combustor of the gas turbine engine. A diffuser frame includes a plurality of struts. Each of the plurality of struts is disposed between a pair of adjacent passages of the plurality of passages. The diffuser frame is configured to couple an inner diffuser case to an outer diffuser case.
FILED	Friday, March 22, 2019
APPL NO	16/361938
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) Non-positive-displacement Pumps F04D 29/542 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11024952 — Broadband dual polarization active artificial magnetic conductor

US 11024952	Quarfoth et al.
FUNDED BY
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Ryan G. Quarfoth (Los Angeles, California); Carson R. White (Agoura Hills, California)
ABSTRACT	A system and method for a dual-polarized active artificial magnetic conductor (AAMC) is presented in this disclosure. An embodiment of the proposed system comprises an array of unit cells that reflects electromagnetic waves polarized parallel to a surface with a zero-degree phase shift. The array of unit cells has impedance elements connected to neighboring impedance elements with non-Foster circuits coupled in a crossover configuration, each impedance element being coupled to a ground with a conductive via.
FILED	Friday, January 25, 2019
APPL NO	16/258501
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 1/364 (20130101) Original (OR) Class H01Q 1/523 (20130101) H01Q 9/16 (20130101) H01Q 21/065 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

11025470 — Communication system and method using orthogonal frequency division multiplexing (OFDM) with non-linear transformation

US 11025470	Robinson
FUNDED BY
APPLICANT(S)	Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S)	Rampart Communications, Inc. (Annapolis, Maryland)
INVENTOR(S)	Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT	A method of encoding data includes identifying multiple complex number pairs of a data vector and generating a transformed data vector by applying a non-linear transformation to each complex number pair from the multiple complex number pairs. The non-linear transformation includes modifying a phase of a first complex number from each complex number pair. The phase modification is based on a value associated with a second complex number from each complex number pair. A signal representing the transformed data vector is sent to multiple transmitters for transmission to multiple receivers. A signal representing the non-linear transformation is sent to a compute device for transmission of the non-linear transformation to the multiple receivers prior to transmission of the signal representing the transformed data vector from the multiple transmitters to the multiple receivers, for recovery of the data vector at the multiple receivers.
FILED	Monday, July 01, 2019
APPL NO	16/459254
ART UNIT	2471 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/0456 (20130101) Multiplex Communication H04J 11/003 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2634 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 01, 2021.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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