FedInvent Patents
Patent Details for Tuesday, June 22, 2021
This page was updated on Saturday, July 17, 2021 at 01:23 AM GMT
Department of Health and Human Services (HHS)
| US 11039811 | Degertekin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); The United States of America, as Represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Fahrettin Levent Degertekin (Atlanta, Georgia); Coskun Tekes (Alpharetta, Georgia); Robert Jay Lederman (Chevy Chase, Maryland); Ozgur Kocaturk (Bethesda, Maryland); M. Wasequr Rashid (Atlanta, Georgia); Maysam Ghovanloo (Atlanta, Georgia) |
| ABSTRACT | An intracardiac imaging system has an MRI compatible intracardiac echography catheter having transmitters, receivers, a multiplexer, and a beamformer. The catheter can include an atraumatic tip disposed on the distal end of the catheter, a pair of inductively coupled coils proximal the atraumatic tip, at least one CMUT-on-CMOS volumetric imaging chip disposed between the pair of coils, and a cable lumen disposed within the volume sized to house a small number of electrical connections due to significant multiplexing in the CMUT-on-CMOS chip. The catheter can be made of MRI compatible materials and can include active cooling channels. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/178665 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 8/12 (20130101) Original (OR) Class A61B 8/56 (20130101) A61B 8/445 (20130101) A61B 8/546 (20130101) A61B 8/0883 (20130101) A61B 8/4254 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0292 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/5208 (20130101) G01S 7/52034 (20130101) G01S 15/8913 (20130101) G01S 15/8925 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040019 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Wenxin Ma (Potomac, Maryland); Lian Zhao (Kensington, Maryland); Xu Wang (Falls Church, Virginia); Wai T. Wong (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods are disclosed for treating and/or preventing retinal degeneration is a subject. In some embodiments, the method includes administering to the subject a therapeutically effective amount of a selective estrogen receptor modulator (SERM) to treat the retinal degeneration in the subject. In other embodiments, the SERM is administered orally. In some examples, the SERM is tamoxifen, afimoxifene, raloxifene, bazedoxifene, arzoxifene, desmethylarzoxifene, or a salt or derivative thereof, or combinations thereof. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 16/325678 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/398 (20210101) A61B 5/4848 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/138 (20130101) Original (OR) Class A61K 31/4535 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040025 | Lamichhane et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF ST. THOMAS (St. Paul, Minnesota) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); University of St. Thomas (St. Paul, Minnesota) |
| INVENTOR(S) | Gyanu Lamichhane (Towson, Maryland); J. Thomas Ippoliti (St. Paul, Minnesota) |
| ABSTRACT | The present invention is a method of treating or preventing Mycobacterium tuberculosis infection in a subject by administering to the subject an effective amount of oxazolidinone, specifically (N-(((S)-3-(dibenzo[b,e][1,4]dioxin-7-yl)-2-oxooxazolidin-5-yl)methyl)acetamide) or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999253 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040042 | Strum et al. |
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| APPLICANT(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Chapel Hill, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis Xavier Tavares (Durham, North Carolina) |
| ABSTRACT | This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC) as well as renal cells, from damage associated with DNA damaging chemotherapeutic agents. In one aspect, improved protection of healthy cells is disclosed using disclosed compounds that act as highly selective and short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects undergoing DNA damaging chemotherapeutic regimens for the treatment of proliferative disorders. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/886309 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/527 (20130101) Original (OR) Class A61K 31/555 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Heterocyclic Compounds C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040054 | Goessling et al. |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Wolfram Goessling (Chestnut Hill, Massachusetts); Saireudee Chaturantabut (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods for the prevention and treatment of an abnormal tissue condition in the liver (e.g., liver cancer) of a subject, based on the administration of an inhibitor of a G protein-coupled estrogen receptor 1 (GPER1). |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/349715 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 38/1774 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040056 | Juliano et al. |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Rudolph L. Juliano (Chapel Hill, North Carolina); Silvia M. Kreda (Mebane, North Carolina); Ling Wang (Chapel Hill, North Carolina); Xin Ming (Chapel Hill, North Carolina); Lindsey Ingerman James (Chapel Hill, North Carolina); Ranathunga Arachchillage Yamuna Kumari Ariyarathna (Carrboro, North Carolina) |
| ABSTRACT | This disclosure is directed to methods, compounds and compositions for delivering nucleic acids to a cell of interest. In particular, it provides salts that are particularly effective in delivering nucleic acids to cells in the lung for disorders such as cystic fibrosis (CF). |
| FILED | Friday, May 10, 2019 |
| APPL NO | 16/409173 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) A61K 31/4985 (20130101) A61K 31/7125 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Heterocyclic Compounds C07D 235/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/314 (20130101) C12N 2310/3233 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040061 | Golobish et al. |
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| APPLICANT(S) | CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | CytoSorbents Corporation (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Monmouth Junction, New Jersey); Tamaz Guliashvili (Monmouth Junction, New Jersey); Pamela O'Sullivan (Monmouth Junction, New Jersey); Andrew Scheirer (Bethlehem, Pennsylvania); Vi Dan (Monmouth Junction, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Monmouth Junction, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769361 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/14 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040082 | Merlin |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia); The United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Didier Merlin (Decatur, Georgia) |
| ABSTRACT | The present invention relates to methods of treating a patient who has colorectal cancer and to methods of reducing the likelihood that a patient will develop or experience a recurrence of colorectal cancer. The methods comprise a step of introducing, to the patient, an effective amount of an agent that targets an intestinal H+-coupled di/tripeptide transporter (PepT1). Useful compositions including, for example, the tripeptide KPV, vectors encoding such peptides, and cells (e.g., bacterial cells) including them, are also within the scope of the present invention, as are kits including such compositions. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/502060 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/655 (20130101) A61K 31/655 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 38/06 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 35/00 (20180101) Peptides C07K 5/0815 (20130101) C07K 5/06026 (20130101) C07K 5/06052 (20130101) C07K 5/06086 (20130101) C07K 5/06165 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040091 | Hammond et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | H. Kirk Hammond (La Jolla, California); Mei Hua Gao (La Jolla, California) |
| ABSTRACT | The invention provides methods for treating, ameliorating or protecting (preventing) an individual or a patient having or at risk of having heart disease or heart failure, or decreased cardiac function, comprising: providing a cyclic adenosine monophosphate-incompetent (cAMP-incompetent) adenylyl cyclase type 6 (AC6) protein or polypeptide (also called “an AC6mut”), or an AC6mut-encoding nucleic acid or a gene operatively linked to a transcriptional regulatory sequence. |
| FILED | Wednesday, June 04, 2014 |
| APPL NO | 14/893905 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/51 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Enzymes C12Y 406/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040099 | Tang |
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| APPLICANT(S) | Altimmune, Inc (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Altimmune, Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | De-Chu C Tang (Plano, Texas) |
| ABSTRACT | The present invention shows that intranasal administration of E1/E3-defective adenovirus particles may confer rapid and broad protection against viral and bacterial pathogens in a variety of disease settings. Protective responses lasted for many weeks in a single-dose regimen in animal models. When a pathogen-derived antigen gene was inserted into the E1/E3-defective adenovirus genome, the antigen-induced protective immunity against the specific pathogen was elicited before the adenovirus-mediated protective response declined away, thus conferring rapid, prolonged, and seamless protection against pathogens. In addition to E1/E3-defective adenovirus, other bioengineered non-replicating vectors encoding pathogen-derived antigens may also be developed into a new generation of rapid and prolonged immunologic-therapeutic (RAPIT). |
| FILED | Saturday, July 11, 2020 |
| APPL NO | 16/926703 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/541 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040100 | Tang |
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| APPLICANT(S) | Altimmune, Inc (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Altimmune Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | De-Chu C Tang (Plano, Texas) |
| ABSTRACT | The present invention shows that intranasal administration of E1/E3-defective adenovirus particles may confer rapid and broad protection against viral and bacterial pathogens in a variety of disease settings. Protective responses lasted for many weeks in a single-dose regimen in animal models. When a pathogen-derived antigen gene was inserted into the E1/E3-defective adenovirus genome, the antigen-induced protective immunity against the specific pathogen was elicited before the adenovirus-mediated protective response declined away, thus conferring rapid, prolonged, and seamless protection against pathogens. In addition to E1/E3-defective adenovirus, other bioengineered non-replicating vectors encoding pathogen-derived antigens may also be developed into a new generation of rapid and prolonged immunologic-therapeutic (RAPIT). |
| FILED | Sunday, July 12, 2020 |
| APPL NO | 16/926704 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/541 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040106 | Burgess et al. |
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| APPLICANT(S) | Small Molecule PPI Mimics LLC (College Station, Texas) |
| ASSIGNEE(S) | Small Molecule PPI Mimics LLC (College Station, Texas) |
| INVENTOR(S) | Kevin Burgess (College Station, Texas); Syed Muhammad Usama (College Station, Texas) |
| ABSTRACT | The present disclosure provides conjugates of kinase inhibitors and cyanine dyes, as well as related compositions, methods and uses. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407264 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4545 (20130101) A61K 47/545 (20170801) Original (OR) Class Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/0083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040108 | Wang et al. |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Huaimin Wang (Waltham, Massachusetts); Bing Xu (Newton, Massachusetts) |
| ABSTRACT | This invention relates to a conjugate of formula (I): (A-Z1-)n-Q-Z2-D (I), wherein Z1, Z2, Q, A, D, and n are as described herein. This invention also relates to a pharmaceutical composition including a pharmaceutically acceptable carrier and a conjugate of formula (I). This invention also relates to a method making a conjugate of formula (I), and the use of the conjugate for treating cancerous conditions, modulating cell membrane microheterogeneity, stimulating an immunoresponse, and forming a network on or near the inner or outer surface of target cells. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/097325 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/351 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 47/00 (20130101) A61K 47/55 (20170801) A61K 47/64 (20170801) Original (OR) Class A61K 47/542 (20170801) A61K 47/554 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040116 | Kaspar et al. |
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| FUNDED BY |
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| APPLICANT(S) | NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Brian K. Kaspar (Westerville, Ohio); Arthur Burghes (Columbus, Ohio); Paul Porensky (Columbus, Ohio) |
| ABSTRACT | The present invention relates to Adeno-associated virus type 9 methods and materials useful for intrathecal delivery of polynucleotides. Use of the methods and materials is indicated, for example, for treatment of lower motor neuron diseases such as SMA and ALS as well as Pompe disease and lysosomal storage disorders. It is disclosed that administration of a non-ionic, low-osmolar contrast agent, together with a rAAV9 vector for the expression of Survival Motor Neuron protein, improves the survival of SMN mutant mice as compared to the administration of the expression vector alone. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502944 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/00 (20130101) A61K 48/0008 (20130101) A61K 48/0075 (20130101) Original (OR) Class A61K 49/0438 (20130101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040124 | Maher et al. |
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| FUNDED BY |
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| APPLICANT(S) | NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (New York, New York) |
| ASSIGNEE(S) | NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (New York, New York) |
| INVENTOR(S) | Suzanne A. Maher (Highland Lakes, New Jersey); Tony Chen (Highland Park, New Jersey); Russell Warren (Greenwich, Connecticut) |
| ABSTRACT | An improved new method of making a multi-component implant comprising a solid hydrogel, a porous hydrogel, and a porous rigid base suitable for implantation into a mammal, to treat, repair or replace defects and/or injury biological tissue as well as the implant made from the improved method. The invention also includes an improved method for making devices, constructs, and materials comprising a hydrogel and a porous rigid material. The invention also includes a mold and kits for performing the methods. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 16/498211 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 2400/06 (20130101) A61L 2400/08 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/03 (20130101) B29C 45/14 (20130101) B29C 45/16 (20130101) B29C 45/26 (20130101) B29C 45/0053 (20130101) B29C 45/7207 (20130101) B29C 2045/1693 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2029/04 (20130101) B29K 2105/04 (20130101) B29K 2105/0061 (20130101) B29K 2239/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040215 | Rubin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS). U.S. GOVERNMENT NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR) (Bethesda, Maryland) |
| INVENTOR(S) | Clinton Rubin (Port Jefferson, New York); Janet Rubin (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention relates to compositions and methods configured to deliver a stimulus (e.g., a therapeutic agent or a therapeutically beneficial signal) to a cell, tissue, organ, or organism. The stimulus is applied at least twice, and the first and second applications are separated by a rest period in which no further stimulus is actively applied. The rest period is of a duration (e.g., about 1-6 hours) sufficient to provoke an enhanced response to the second stimulus. |
| FILED | Friday, July 20, 2018 |
| APPL NO | 16/040659 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 31/002 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/326 (20130101) A61N 2/00 (20130101) A61N 2/02 (20130101) Original (OR) Class A61N 5/062 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040217 | Shafirstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Health Research, Inc. (Buffalo, New York) |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Gal Shafirstein (Amherst, New York); Brian Wrazen (Cheektowaga, New York); Nestor Rigual (Buffalo, New York) |
| ABSTRACT | A system and method for interstitial photodynamic light therapy (I-PDT) of a tissue. A plurality of light-transmitting catheters (LTCs) are provided and placed in the tissue according to a pre-determined treatment plan, wherein an LTC includes a first treatment fiber disposed therethrough, and an LTC includes a dosimetry fiber disposed therethrough. A dose light is provided to the tissue by way of the first treatment fiber according to the pre-determined treatment plan. Light received at the dosimetry fiber is measured using a spectrometer in operable communication with the dosimetry fiber. One or more properties of a photosensitizer in the tissue are determined. The treatment plan is modified based on the properties of the photosensitizer, and an updated dose light is provided to the tissue by way of the first treatment fiber according to the modified treatment plan. |
| FILED | Monday, July 25, 2016 |
| APPL NO | 15/746699 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/24 (20130101) A61B 2017/00061 (20130101) A61B 2018/00642 (20130101) A61B 2018/00702 (20130101) A61B 2018/00779 (20130101) A61B 2018/2261 (20130101) A61B 2018/20554 (20170501) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0601 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/0612 (20130101) A61N 2005/0627 (20130101) A61N 2005/0628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040935 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Beibei Chen (Pittsburgh, Pennsylvania); Rama K. Mallampalli (Pittsburgh, Pennsylvania); Yuan Liu (Pittsburgh, Pennsylvania) |
| ABSTRACT | Described herein are compounds that disrupt the interaction between Fbxo48 and phosphorylated-AMPK. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 16/339534 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Acyclic or Carbocyclic Compounds C07C 215/08 (20130101) C07C 215/18 (20130101) C07C 217/34 (20130101) Original (OR) Class Heterocyclic Compounds C07D 205/04 (20130101) C07D 217/04 (20130101) C07D 311/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040942 | Pluth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael D. Pluth (Eugene, Oregon); Yu Zhao (Eugene, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of a donor compound that releases COS and/or CS2, which can be converted to H2S. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. Methods of making and using the donor compound embodiments also are disclosed. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262226 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 333/08 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/527 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 2333/988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040947 | Ojima et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Iwao Ojima (Port Jefferson, New York); Vincent Alford (Lake Grove, New York); Anushree Kamath (Waltham, Massachusetts); Jian Cao (S. Setauket, New York); Xiadong Ren (Port Jefferson Station, New York); Nicole Sampson (Setauket, New York); Monaf Awwa (Stony Brook, New York) |
| ABSTRACT | A compound of Formula I: wherein:
|
| FILED | Thursday, March 22, 2018 |
| APPL NO | 16/494984 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/56 (20130101) C07D 239/95 (20130101) Original (OR) Class C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040951 | Volpe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Matthew R. Volpe (Cambridge, Massachusetts); Emily Patricia Balskus (Somerville, Massachusetts); Matthew Ryan Wilson (Cambridge, Massachusetts) |
| ABSTRACT | The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/542583 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 311/16 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040957 | Ciblat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Syros Pharmaceuticals, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Syros Pharmaceuticals, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Stephane Ciblat (Montreal, Canada); Patrick Deroy (Blainville, Canada); Nathanael Gray (Boston, Massachusetts); Melissa Leblanc (Laval, Canada); Jason J. Marineau (Franklin, Massachusetts); Joel Moore (Lexington, Massachusetts); Kevin Sprott (Needham, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); M. Arshad Siddiqui (Newton, Massachusetts); Anzhelika Kabro (Montreal, Canada); Serge Leger (Notre-Dame-de-L'ile-Perrot, Canada); Stephanie Roy (Lachine, Canada); Darby Schmidt (Arlington, Massachusetts); Dana K. Winter (Rigaud, Canada); Michael Bradley (Allston, Massachusetts); Tom Miller (Wakefield, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7)), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject. |
| FILED | Wednesday, December 05, 2018 |
| APPL NO | 16/210264 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040959 | Beutler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California); The Board of Regents of the University of Texas System (Austin, Texas); Bruce Beutler (Dallas, Texas); Dale L. Boger (La Jolla, California) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas); The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Bruce Beutler (Dallas, Texas); Dale L. Boger (La Jolla, California) |
| ABSTRACT | A diprovocim compound that corresponds in structure to structural Formula V is disclosed, wherein A, W, Z, R1, R2, R3 and R4 (when present) are defined within. A diprovocim compound has immune-adjuvant properties on human and mouse cells in culture and on in vivo immunization of mice. A composition containing a diprovocim and a method of using a compound are also disclosed. The immunostimulatory activity of a diprovocim compound is similar to that of LPS, to which there is no apparent structural similarity. A contemplated compound bears no structural similarity to either the TLR1/TLR2 lipoprotein agonists nor to any other synthetic TLR agonist, and is remarkably easy to prepare and synthetically modify. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 16/303043 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Heterocyclic Compounds C07D 403/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040976 | Maianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Revere, Massachusetts); David R. Liu (Lexington, Massachusetts) |
| ABSTRACT | Provided herein are compounds of Formulae (RL), (I), (II), (III), (IV), and (V), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, prodrugs, and isotopically labeled derivatives thereof. Also provided are pharmaceutical compositions, kits, and methods involving the inventive compounds for the treatment of metabolic disorders (e.g., diabetes, hyperglycemia, impaired glucose tolerance, insulin resistance, obesity). The compound are useful as substrate selective inhibitors of insulin-degrading enzyme (IDE). |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/568930 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Acyclic or Carbocyclic Compounds C07C 311/16 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 211/14 (20130101) C07D 211/16 (20130101) C07D 211/96 (20130101) C07D 241/44 (20130101) C07D 295/26 (20130101) C07D 295/185 (20130101) C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) C07D 413/06 (20130101) C07D 413/12 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 487/08 (20130101) C07D 493/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041003 | Hook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Magnus Hook (Houston, Texas); Ya-Ping Ko (Sugar Land, Texas); Emanuel Smeds (Sodra Sanby, Sweden); Vannakambadi K. Ganesh (Pearland, Texas) |
| ABSTRACT | The present invention discloses crystal structure of Staphylococcus aureus Clumping factor A (ClfA) in complex with fibrinogen (Fg) derived peptide. Also, the present invention also discloses the use of this structure in the design of ClfA targeted vaccines and therapeutic agents (including monoclonal antibodies). In addition, the present invention discloses isolated and purified engineered Staphylococcus clumping factor A protein (ClfA) with a stabilized, closed conformation and immunogenic compositions thereof including methods of treating a Staphylococcus infection in an individual. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/160625 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 14/75 (20130101) C07K 16/1271 (20130101) C07K 2319/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041004 | Pan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Zhuo-Hua Pan (Troy, Michigan) |
| ABSTRACT | The invention provides compositions and kits including at least one nucleic acid or polypeptide molecule encoding for a mutant CoChop protein. Methods of the invention include administering a composition comprising a mutant CoChop to a subject to preserve, improve, or restore phototransduction. Preferably, the compositions and methods of the invention are provided to a subject having impaired vision, thereby restoring vision to normal levels. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 16/328916 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 14/405 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
11041008 — Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia
| US 11041008 | Bergamaschi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | the Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The Government of the United States of America as Represented by The Secretary of the Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Cristina Bergamaschi (Frederick, Maryland); Barbara K. Felber (Rockville, Maryland); George N. Pavlakis (Rockville, Maryland); Antonio Valentin (Frederick, Maryland) |
| ABSTRACT | The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15. The present invention also provides methods for preventing, alleviating, reducing, and/or inhibiting lymphopenia or peripheral depletion of lymphocytes in a patient in need thereof by administering to the patient IL-15. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123431 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 45/06 (20130101) A61K 47/6813 (20170801) A61K 47/6835 (20170801) A61K 48/005 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/54 (20130101) C07K 14/5443 (20130101) Original (OR) Class C07K 14/7155 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 5/163 (20130101) C12N 15/09 (20130101) C12N 15/62 (20130101) C12N 15/1138 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/30 (20130101) C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041011 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); National Institutes of Health (NIH) (Bethesda, Maryland); U.S. Dept. of Health And Human Services (DHHS) (Bethesda, Maryland); U.S. Government NIH Division of Extramural Inventionsl and Technology Resources (DEITR) (Bethesda, Maryland) |
| INVENTOR(S) | Yukai He (Martinez, Georgia); Wei Zhu (Augusta, Georgia); Esteban Celis (Augusta, Georgia); Yibing Peng (Augusta, Georgia); Lan Wang (Augusta, Georgia) |
| ABSTRACT | T cell receptors that specifically recognize hAFP158 and methods of their use are provided. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969211 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041012 | Scholler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Nathalie Scholler (Narberth, Pennsylvania); Katarzyna Urbanska (Philadelphia, Pennsylvania); Daniel J. Powell (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298310 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) Peptides C07K 14/465 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041023 | Vale et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ronald D. Vale (Tiburon, California); Meghan A. Morrissey (San Francisco, California); Adam P. Williamson (Berkeley, California) |
| ABSTRACT | The present disclosure generally relate to chimeric antigen receptors (CARs) that bind an engulfment receptor expressed on the surface of a phagocytic cell and activate the endogenous phagocytic signaling pathway. Also disclosed are compositions and methods useful for producing such CARs, nucleic acids encoding same, phagocytic cells that have been modified to include a targeted effector activity directed towards a cell of interest such as, e.g., a cancer cell, as well as for modifying a cell and/or for the treatment of various health disorders such as cancer, including solid tumor and hematologic malignancy. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821551 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4748 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041050 | Davis et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute Of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Mark E. Davis (Pasadena, California); Dorothy Pan (Pasadena, California) |
| ABSTRACT | The present disclosure is directed to nanoparticle delivery systems for delivering biological agents, pharmaceutical compositions of comprising these nanoparticles, and methods of using these compositions. Certain embodiments of the present disclosure provide nanoparticles comprising polymers comprising alternating charged and uncharged segments comprising one or more of the following structural units of Formula (I) Formula (III): wherein A is an uncharged segment comprising polyalkylene glycol; and B is a cationically charged segment comprising at least one polyhydroxy linkage. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880065 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 47/34 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/40 (20130101) C08G 73/028 (20130101) C08G 79/08 (20130101) C08G 81/00 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041150 | Marshall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| INVENTOR(S) | Lewis A. Marshall (Oakland, California); Amy L. Hiddessen (Pleasanton, California); Nathan P. Hoverter (Pleasanton, California); Klint A. Rose (Oakland, California); Juan G. Santiago (Stanford, California); Matthew S. Munson (Evanston, Illinois); Janine Mok (Palo Alto, California); Sean Arin (Oakland, California); Yatian Qu (Sunnyvale, California); Andrew Lee (Hayward, California); Michael Christopher DeRenzi (Danville, California) |
| ABSTRACT | The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052565 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/502738 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 9/527 (20130101) B01L 2200/0621 (20130101) B01L 2200/0642 (20130101) B01L 2400/0421 (20130101) B01L 2400/0688 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44704 (20130101) G01N 27/44717 (20130101) G01N 27/44743 (20130101) G01N 27/44791 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041151 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Lloyd Smith (Madison, Wisconsin); Cheng-Hsien Wu (Burlingame, California) |
| ABSTRACT | Described herein are RNA arrays, and compositions and methods for generating RNA arrays, particularly high density RNA arrays. The disclosed methods for generating RNA arrays utilize template DNA arrays and RNA polymerase to generate RNA arrays. In some embodiments, the disclosed methods use an RNA polymerase and modified ribonucleosides to generate modified RNA arrays for various applications, e.g. RNA arrays having higher nuclease resistance, more conformationally stable RNA arrays, and higher binding affinity RNA aptamer arrays. In some embodiments, the disclosed methods are used to generate RNA bead arrays. |
| FILED | Thursday, December 07, 2017 |
| APPL NO | 15/834138 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/005 (20130101) B01J 2219/00529 (20130101) B01J 2219/00585 (20130101) B01J 2219/00596 (20130101) B01J 2219/00605 (20130101) B01J 2219/00711 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1068 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2525/113 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041154 | Kiani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Samira Kiani (Scottsdale, Arizona); Xiao Wang (Chandler, Arizona); David Menn (Tempe, Arizona); Mo Reza Ebrahimkhani (Scottsdale, Arizona) |
| ABSTRACT | Provided herein are tools for understanding and engineering dynamics of synthetic genetic circuits which utilize CRISPR components. More particularly, methods, systems, and compositions for directing Cas9 activity using a fluorescent guide RNA (fgR-NA) which fluoresces in the presence of small molecules (e.g., DFHBI-IT) are described and illustrated in the present provisional application. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 16/632792 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/15 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041155 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Rebecca Tayler Cottman (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are engineered CCCTC-binding factor (CTCF) variants that can bind to mutant CTCF binding sequences and method of using the same. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415989 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/1044 (20130101) C12N 15/1135 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041161 | Avalos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jose Luis Avalos (Arlington, Massachusetts); Gerald Fink (Chestnut Hill, Massachusetts); Gregory Stephanopoulos (Winchester, Massachusetts) |
| ABSTRACT | Metabolic flux biosensors are provided herein, as are related compositions and methods useful for, inter alia, identifying factors which increase the production of metabolites and/or end products of metabolic pathways, and for the production of inter alia, metabolites and/or end products of metabolic pathways. |
| FILED | Thursday, January 08, 2015 |
| APPL NO | 15/110158 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/395 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1025 (20130101) C12N 15/81 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 7/16 (20130101) C12P 13/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5038 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041170 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland); Thomas Jefferson University (Harleysville, Pennsylvania); University of Maryland (Baltimore, Maryland) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania); The United States of America, as represented by the Secretary, Department of Health and Human Service (Rockville, Maryland); University of Maryland (Baltimore, Maryland) |
| INVENTOR(S) | Reed F. Johnson (Frederick, Maryland); Matthias Schnell (Harleysville, Pennsylvania); Lisa E. Hensley (Frederick, Maryland); Christoph Wirblich (Philadelphia, Pennsylvania); Christopher M. Coleman (Owings Mills, Maryland); Matthew B. Frieman (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a coronavirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a coronavirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present disclosure provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one coronavirus immunogenic glycoprotein fragment, as well as pharmaceutical compositions comprising the vaccine vectors. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 16/091005 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/205 (20130101) A61K 39/215 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Workshop Equipment, e.g for Marking-out Work; Storage Means for Workshops B25H 3/003 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2760/20034 (20130101) C12N 2760/20043 (20130101) C12N 2760/20134 (20130101) C12N 2760/20143 (20130101) C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041173 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Randall Jeffrey Platt (Cambridge, Massachusetts); Guoping Feng (Cambridge, Massachusetts); Yang Zhou (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/349603 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 67/0278 (20130101) A01K 2217/05 (20130101) A01K 2217/07 (20130101) A01K 2217/052 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/01 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/8213 (20130101) C12N 15/8509 (20130101) C12N 2800/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041182 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Government of the United States of America (Rockville, Maryland); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Yun-Xing Wang (Frederick, Maryland); Yu Liu (Frederick, Maryland); Rui Sousa (San Antonio, Texas) |
| ABSTRACT | The invention relates to a method for synthesizing a selectively labeled RNA, and an apparatus for performing the method. Specific segments or discrete residues within the RNA may be selectively labeled, and different segments may include different labels. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/258021 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/119 (20130101) C12Q 2563/149 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041187 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Brian T. Cunningham (Champaign, Illinois); Yue Zhuo (Champaign, Illinois); Brendan Harley (Urbana, Illinois); Ji Sun Choi (Urbana, Illinois); Thibault Marin (Champaign, Illinois); Yi Lu (Champaign, Illinois) |
| ABSTRACT | A digital assay for a micro RNA (miRNA) or other target analyte in a sample makes use of nanoparticles that absorb light at the resonant wavelength of a photonic crystal (PC). Such nanoparticles locally quench the resonant reflection of light from the PC when present on the surface of the PC. The nanoparticles are functionalized to specifically bind to the target analyte, and the PC surface is functionalized to specifically bind to the nanoparticles that have bound to the target analyte. The sample is exposed to the functionalized nanoparticles, and the individual nanoparticles bound to the PC surface can be identified and counted based on reduced intensity values in the reflected light from the PC. The number of bound nanoparticles that are counted in this way can be correlated to the abundance of the target analyte in the sample. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170111 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041193 | Rasmussen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Randy P. Rasmussen (Salt Lake City, Utah); Robert John Crisp (Salt Lake City, Utah); Andrew Clinton Hemmert (Murray, Utah); Elizabeth Barker Campbell (Orem, Utah); Thomas Charles Robbins (Salt Lake City, Utah); David J. Eyre (Salt Lake City, Utah) |
| ABSTRACT | Methods and devices are provided for simultaneously amplifying a plurality of sample wells for a predetermined amount of amplification, detecting whether amplification has occurred in a first set of the wells, amplifying for an additional amount of amplification and detecting whether amplification has occurred in a second set of the wells. Methods are also provided for analyzing a target nucleic acid sequence using melt curves that were generated in a plurality of amplification cycles. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037948 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/689 (20130101) C12Q 1/705 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 2527/107 (20130101) C12Q 2537/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041201 | Yu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aiming Yu (Granite Bay, California) |
| ABSTRACT | Provided are polynucleotides that find use, e.g., for detecting RNase activity. In certain embodiments, the polynucleotide comprises a tRNA operably linked to a pre-microRNA (pre-miRNA), and an aptamer that binds to a detectable label. According to some embodiments, the detectable label is a fluorescent dye, non-limiting examples of which include malachite green, tetramethylrosamine, sulforhodamine B, and a triphenylmethane dye. Also provided are compositions that include the polynucleotides of the present disclosure. Also provided are kits that include a polynucleotide of the present disclosure and a detectable label to which the aptamer of the polynucleotide binds. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577762 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/141 (20130101) C12N 2310/3519 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/6876 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041202 | Robins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADAPTIVE BIOTECHNOLOGIES Corporation (Seattle, Washington); FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | Adaptive Biotechnologies Corporation (Seattle, Washington); Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Harlan S. Robins (Seattle, Washington); Aude Georgiana Chapuis (Seattle, Washington); Thomas M. Schmitt (Seattle, Washington); Philip Greenberg (Seattle, Washington); Anna Sherwood (Seattle, Washington) |
| ABSTRACT | Methods are provided for identifying T cell receptors that specifically bind a particular antigenic target and can be used as therapeutics against disease. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/563365 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6881 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/56977 (20130101) G01N 2333/7051 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041204 | Kwiatkowski, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Thomas J. Kwiatkowski, Jr. (Cambridge, Massachusetts); Robert H. Brown, Jr. (Needham, Massachusetts) |
| ABSTRACT | The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and methods of use thereof including methods relating to the diagnosis of ALS or other related motor neuron disease by virtue of the presence of the mutant FUS/TLS sequence(s). |
| FILED | Tuesday, August 25, 2015 |
| APPL NO | 14/834737 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041205 | Siddique et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Teepu Siddique (Chicago, Illinois); Wenjie Chen (Chicago, Illinois); Han-Xiang Deng (Chicago, Illinois); Yi Yang (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions and methods for diagnosis, risk assessment, research, and therapy related to amyotrophic lateral sclerosis (ALS) and ALS-related disorders. In particular, the present invention relates to mutations in the UBQLN2 gene that cause dominantly inherited chromosome X-linked ALS and ALS/dementia. |
| FILED | Friday, September 18, 2015 |
| APPL NO | 14/858692 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/28 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041207 | Clelland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (Menands, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (Menands, New York) |
| INVENTOR(S) | Catherine L. Clelland (New York, New York); James D. Clelland (New York, New York) |
| ABSTRACT | The present invention provides, inter alia, methods for treating or ameliorating the effects of a disorder, such as schizophrenia or bipolar disorder, by increasing or decreasing proline levels. Further provided are methods of predicting and monitoring the clinical response in a patient, and diagnostic systems for identifying a patient likely to benefit from proline modulation. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977144 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/198 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101) G01N 2800/302 (20130101) G01N 2800/304 (20130101) G01N 2800/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041208 | Fairchild et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| INVENTOR(S) | Robert L. Fairchild (Mayfield Village, Ohio); Roslyn Bernstein Mannon (Birmingham, Alabama) |
| ABSTRACT | Provided herein are compositions, systems, kits, and methods for detecting rejection, or an elevated risk of rejection, of an organ or tissue graft (e.g., kidney graft) in a subject by detecting one, or a panel of, RNA markers in a urine sample from the subject. In certain embodiments, kidney graft injury is detected by measuring one or more of the RNA markers disclosed herein. In some embodiments, the one or more markers are employed to distinguish between acute graft rejection and BK virus nephropathy. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/110964 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041212 | Ting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | Angela H. Ting (Cleveland, Ohio); Byron H. Lee (Cleveland, Ohio) |
| ABSTRACT | A method of providing a prognosis or diagnosis of prostate cancer in a subject is described. The method includes obtaining a urine or prostate sample from the subject; determining the level of expression of ABCA1 in the sample; and comparing the level of expression of ABCA1 in the sample to the level of a control sample, wherein a decreased level of ABCA1 expression compared to the control indicates the subject has prostate cancer or a more severe form of prostate cancer. Methods of treating subjects identified as having prostate cancer, and kits for carrying out the method of prognosis or diagnosis are also described. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/048487 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041807 | Shroff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary, Depart. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Hari Shroff (Rockville, Maryland); Yicong Wu (Rockville, Maryland) |
| ABSTRACT | Various embodiments of a multi-photon microscopy system that uses sequential excitation of a sample through three or more objective lenses oriented at different axes intersecting the sample are disclosed. Each objective lens is capable of focused sequential excitation of the sample that elicits fluorescence emissions from the excited sample, which is then simultaneously detected by each respective objective lens along a respective longitudinal axis every time the sample is illuminated through only a single objective lens. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/754948 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/002 (20130101) G02B 21/16 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041808 | Mayerich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | David Mayerich (Houston, Texas); Jason Eriksen (Houston, Texas) |
| ABSTRACT | Imaging systems and methods, referred to herein as surface ablation lathe tomography (SALT), may be capable of providing whole organ tomography to provide 3D imaging. The system may provide a UV source that excites a sample, and a camera may capture imaging of fluorescent emission cause by the excitation. The tissue sample may be treated or stained with an imaging agent, such as fluorescent markers with fluorescently-tagged antibodies. The sample may also be infused with and/or embedded in paraffin wax. The tissue sample embedded in paraffin may be placed on a rotating mechanism that rotates, while the UV source excites a desired region and the camera captures imaging of a thin surface layer or shell of the sample. The system may also provide an ablation mechanism, such as a microtome blade or lathe, to ablate surface of the sample during rotation to allow imaging of subsequent layers of the sample. Once the sample has been fully imaged, a 3D map of the tissue sample, which may be an entire organ, can be provided. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 16/488785 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2001/002 (20130101) G01N 2001/045 (20130101) G01N 2021/6495 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0036 (20130101) G02B 21/362 (20130101) G02B 21/367 (20130101) Image Data Processing or Generation, in General G06T 7/55 (20170101) G06T 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041849 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | APTITUDE MEDICAL SYSTEMS, INC. (Santa Barbara, California) |
| ASSIGNEE(S) | APTITUDE MEDICAL SYSTEMS, INC. (Goleta, California) |
| INVENTOR(S) | Jinpeng Wang (Santa Barbara, California); Brian Ferguson (Santa Barbara, California); Qiang Gong (Santa Barbara, California) |
| ABSTRACT | The present disclosure provides methods, kits and compositions for identifying nucleic acid agents having a desired property, e.g., a property of specifically binding to a target (such as a protein target) with high affinity. More specifically, the present disclosure provides methods, kits and compositions for identifying candidate nucleic acid agents with both high specificity and affinity for a target. |
| FILED | Tuesday, November 14, 2017 |
| APPL NO | 16/463671 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1048 (20130101) C12N 2320/11 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) C40B 40/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/5308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041850 | Bertozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carolyn R. Bertozzi (Stanford, California); Peter V. Robinson (Berkeley, California); Cheng-Ting Tsai (Berkeley, California) |
| ABSTRACT | Methods are provided for detecting a glycosylated target protein in a sample. Aspects of the methods include: (a) contacting a sample comprising a probe-labeled glycosylated target protein with: (i) a first conjugate comprising a first nucleic acid tag linked to a first capture agent that specifically binds the target protein; (ii) a second conjugate comprising a second nucleic acid tag linked to a second capture agent that specifically binds the probe; and (iii) a bridging nucleic acid that hybridizes to the first and second nucleic acid tags; under conditions sufficient to specifically bind the first and second capture agents to the probe-labeled target protein and to hybridize the bridging nucleic acid to the first and second nucleic acid tags to produce a nucleic acid complex; and (b) detecting the nucleic acid complex. Also provided are compositions and kits useful in practicing various embodiments of the subject methods. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/741728 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/532 (20130101) Original (OR) Class G01N 2400/02 (20130101) G01N 2440/38 (20130101) G01N 2458/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041859 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Yuan Chen (Arcadia, California); Chih-Hong Chen (Duarte, California); Andrew Namanja (Duarte, California) |
| ABSTRACT | Provided herein are methods of detecting binding of an SENP1 polypeptide to a compound and methods for screening for inhibitors of SENP1. Further provided are aqueous compositions comprising SENP1 polypeptides and NMR apparatuses comprising the compositions for NMR analysis. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783423 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2440/36 (20130101) G01N 2500/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041862 | Moller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David R. Moller (Ellicott City, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David R. Moller (Ellicott City, Maryland) |
| ABSTRACT | Sarcoidosis is a multisystem disease characterized by granulomatous inflammation in affected organs. The present invention discloses kits and a system for a blood test using mycobacterial catalase-peroxidase that has a high positive predictive value for confirming a diagnosis of sarcoidosis. |
| FILED | Friday, February 23, 2018 |
| APPL NO | 15/903622 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/28 (20130101) C12Q 1/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6866 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/57 (20130101) G01N 2800/24 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041865 | Fu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Qin Fu (Beverly Hills, California); Jennifer Eileen Van Eyk (Los Angeles, California); Vidya Venkatraman (Los Angeles, California) |
| ABSTRACT | The present invention relates to the field of myocardial injury. More specifically, the present invention provides methods and compositions useful in the diagnosis, prognosis and/or assessment of myocardial injury. In a specific embodiment, a method comprises the steps of (a) diagnosing a subject as having myocardial injury based on the statistically significant over expression of one or more markers described herein compared to a baseline value, wherein the markers are measured in a biological sample obtained from the subject; and (b) treating the subject with one or more of an anti-thrombolysis agent, coronary bypass surgery or angioplasty. |
| FILED | Monday, February 22, 2016 |
| APPL NO | 15/552095 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/46 (20130101) G01N 2333/79 (20130101) G01N 2333/908 (20130101) G01N 2333/916 (20130101) G01N 2333/4704 (20130101) G01N 2333/4722 (20130101) G01N 2440/00 (20130101) G01N 2800/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041868 | Ring et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Aaron Michael Ring (New Haven, Connecticut); Aashish Manglik (Menlo Park, California); Andrew Kruse (Roslindale, Massachusetts); Brian K. Kobilka (Palo Alto, California) |
| ABSTRACT | Provided herein are several methods for selecting agents that bind to transmembrane receptors in a conformationally-selective way. In some embodiments, the method may comprise producing: a transmembrane receptor in an active conformation; and said transmembrane receptor in an inactive conformation and using cell sorting to select, from a population of cells comprising a library of cell surface-tethered extracellular capture agents, cells that are specifically bound to either the transmembrane receptor in its active conformation or the transmembrane receptor in its inactive conformation, but not both. In other embodiments, the method may comprise: contacting a GPCR with a population of cells that comprise a library of surface-tethered extracellular proteins; labeling the cell population with a conformationally-specific binding agent, e.g., a G-protein or mimetic thereof; and using cell sorting to select from the cell population cells that bind to the agent. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673838 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/70571 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 33/566 (20130101) G01N 33/6842 (20130101) G01N 2333/726 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042016 | Mertz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Jerome Mertz (Newton, Massachusetts); Amaury Badon (Brookline, Massachusetts); Timothy Weber (Brookline, Massachusetts); Sheng Xiao (Allston, Massachusetts); Jean-Marc Tsang Min Ching (Brookline, Massachusetts) |
| ABSTRACT | A Multi-Z confocal microscopy system can simultaneously record from multiple Z-sections, and thus performs high speed volumetric imaging. An illumination line can be formed by under-filling the illumination beam in the aperture of the microscope objective. The illumination line extends in the Z dimension into the target sample to be imaged and an X-Y scanning mechanism can be used to scan the illumination line over the sample. The detection signal emanating from the scanned sample can be collected through the full numerical aperture of the microscope objective and directed to a detector subsystem. The detector subsystem includes an array of reflecting pinhole detectors and each reflecting pinhole detector is configured to image a volume at a different depth in the sample. This configuration enables reflecting pinhole detector array to image more than one depth volume at the same time. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217791 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/08 (20130101) G02B 21/004 (20130101) G02B 21/006 (20130101) G02B 21/0032 (20130101) G02B 21/0048 (20130101) G02B 21/0052 (20130101) Original (OR) Class G02B 27/10 (20130101) G02B 27/145 (20130101) G02B 27/0977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042019 | Simpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Garth Jason Simpson (West Lafayette, Indiana); James Ulcickas (West Lafayette, Indiana); Fengyuan Deng (Watertown, Massachusetts); Changqin Ding (West Lafayette, Indiana) |
| ABSTRACT | A method for imaging a sample, wherein the sample changes a polarization state of light as a function of position, wherein the method includes changing a polarization state of a purely polarized light of an incident light striking a micro-retarder array, thereby inducing a changed polarization state of the polarization state. The micro-retarder array is placed in a rear conjugate focal plane of a microscope. The method additionally includes projecting the changed polarization state of the polarization state into an object plane of the microscope containing the sample. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713838 |
| ART UNIT | 2424 — Cable and Television |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/26 (20130101) G02B 21/367 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10056 (20130101) G06T 2207/20212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043282 | Vaske et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNVIERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Charles J. Vaske (Santa Cruz, California); Stephen C. Benz (Santa Cruz, California); Joshua M. Stuart (Santa Cruz, California); David Haussler (Santa Cruz, California) |
| ABSTRACT | The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 15/667535 |
| ART UNIT | 3619 — Semiconductors/Memory |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 25/00 (20190201) G16B 40/00 (20190201) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE48599 | Podack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Eckhard R. Podack (Coconut Grove, Florida); Taylor H. Schreiber (Miami, Florida); Samia Q. Khan (Miami, Florida) |
| ABSTRACT | Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific immune responses, are described. Also described are combination therapies that include the administration of a TNFRSF25 agonist and an interleukin (e.g., IL-2) and/or an mTOR inhibitor (e.g., rapamycin). |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366676 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/7088 (20130101) A61K 38/20 (20130101) A61K 38/2013 (20130101) A61K 39/395 (20130101) A61K 39/3955 (20130101) Original (OR) Class Peptides C07K 14/52 (20130101) C07K 14/55 (20130101) C07K 16/246 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11039782 | Inan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Omer T. Inan (Atlanta, Georgia); Michael N. Sawka (Atlanta, Georgia); Jennifer O. Hasler (Atlanta, Georgia); Hakan Toreyin (Atlanta, Georgia); Mindy L. Millard-Stafford (Atlanta, Georgia); Geza Kogler (Atlanta, Georgia); Sinan Hersek (Atlanta, Georgia); Caitlin Teague (Atlanta, Georgia) |
| ABSTRACT | Multi-modal sensing relating to joint acoustic emission and joint bioimpedance. Custom-design analog electronics and electrodes provide high resolution sensing of bioimpedance, microphones and their front-end electronics for capturing sound signals from the joints, rate sensors for identifying joint motions (linear and rotational), and a processor unit for interpretation of the signals. These components are packed into a wearable form factor, which also encapsulates the hardware required to minimize the negative effects of motion artifacts on the signals. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/577253 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) A61B 5/053 (20130101) A61B 5/0295 (20130101) A61B 5/0537 (20130101) A61B 5/1116 (20130101) A61B 5/1123 (20130101) A61B 5/4528 (20130101) A61B 5/4585 (20130101) Original (OR) Class A61B 5/4878 (20130101) A61B 5/6828 (20130101) A61B 7/006 (20130101) A61B 2562/0204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040061 | Golobish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | CytoSorbents Corporation (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Monmouth Junction, New Jersey); Tamaz Guliashvili (Monmouth Junction, New Jersey); Pamela O'Sullivan (Monmouth Junction, New Jersey); Andrew Scheirer (Bethlehem, Pennsylvania); Vi Dan (Monmouth Junction, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Monmouth Junction, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769361 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/14 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040097 | Richardson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles Richardson (Cambridge, Massachusetts); Thomas S. Vedvick (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); William Tino (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/870020 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5258 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040106 | Burgess et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Small Molecule PPI Mimics LLC (College Station, Texas) |
| ASSIGNEE(S) | Small Molecule PPI Mimics LLC (College Station, Texas) |
| INVENTOR(S) | Kevin Burgess (College Station, Texas); Syed Muhammad Usama (College Station, Texas) |
| ABSTRACT | The present disclosure provides conjugates of kinase inhibitors and cyanine dyes, as well as related compositions, methods and uses. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407264 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4545 (20130101) A61K 47/545 (20170801) Original (OR) Class Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/0083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040141 | El-Khatib et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| INVENTOR(S) | Firas H. El-Khatib (Allston, Massachusetts); Edward R. Damiano (Acton, Massachusetts) |
| ABSTRACT | A blood glucose control system can generate an indication of total carbohydrate therapy over a period during use by a subject. The system can be connected to a medicament pump configured to deliver insulin therapy, other types of medicament therapy, or a combination of medicament therapies to the subject. The system can determine an amount of a counter-regulatory agent to respond to an impending risk of hypoglycemia or an episode of hypoglycemia and determine a dose of carbohydrate therapy based at least in part on the amount of the counter-regulatory agent. The system can track determined doses of carbohydrate therapy to generate the indication of total carbohydrate therapy over the period. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062022 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/14244 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/16 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/3553 (20130101) A61M 2205/3561 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 20/17 (20180101) G16H 20/60 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040226 | Wheatley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | D. Wheatley Enterprises, Inc. (Belcamp, Maryland) |
| ASSIGNEE(S) | D. WHEATLEY ENTERPRISES, INC. (Belcamp, Maryland) |
| INVENTOR(S) | David Wheatley (Belcamp, Maryland); Patrick Hulbert (Belcamp, Maryland); Stanley Rodowsky (Belcamp, Maryland) |
| ABSTRACT | Disclosed is a modular serviceable cartridge assembly for a respirator exhalation unit that is simple in construction and that allows quick-connect of an exhalation valve cartridge in a mask to minimize the need for reconfiguration when changing personal protective equipment, and that allows for easy removal and breakdown for servicing and/or replacement of individual components of the exhalation valve without modifying or replacing other elements of the protective mask. The assembly may be convertible from a negative pressure valve assembly to a positive pressure valve assembly, and vice versa, and a grill may be provided on an outlet side of the cartridge assembly, the rotation of which converts the assembly from a negative pressure valve to a positive pressure valve. |
| FILED | Tuesday, May 07, 2019 |
| APPL NO | 16/404883 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 9/02 (20130101) A62B 9/027 (20130101) A62B 18/00 (20130101) A62B 18/02 (20130101) A62B 18/08 (20130101) A62B 18/10 (20130101) Original (OR) Class A62B 18/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040323 | Talapin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Dmitri V. Talapin (Riverside, Illinois); Hao Zhang (Urbana, Illinois); Vishwas Srivastava (Chicago, Illinois) |
| ABSTRACT | Colloids comprising inorganic nanocrystals dispersed in a molten salt or a liquid metal are provided. The molten salt may comprise an ion which is a Lewis acid or a Lewis base in the presence of the inorganic nanocrystals. Solid composites formed from the colloids are also provided. Methods of using the colloids as media for inducing chemical transformations using the inorganic nanocrystals are also provided. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/772950 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0004 (20130101) B01J 13/06 (20130101) B01J 13/0043 (20130101) B01J 13/0047 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040682 | Uras |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paradigm Research and Engineering, LLC (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Paradigm Research and Engineering, LLC (, None) |
| INVENTOR(S) | Mehmet Uras (Ann Arbor, Michigan) |
| ABSTRACT | A system includes at least one sensor, an electronics module, an energy storage, and an energy harvesting module. The sensor includes a base, at least one core assembly body, a coil, and a fixed magnet. The base is displaced in accordance with an acceleration. A sensor body reacts to the acceleration. The sensor includes a magnetic circuit powered by a fixed or permanent magnet. Magnetic flux flows through the core assembly body and out of the sensor body into the base and back into the sensor body through another core assembly body. The sensor system detects the acceleration and deploys safety systems of a vehicle. Safety systems may include airbags, seatbelts, or other safety systems of the vehicle. The sensor and the system have applications in both military and civilian sectors such as landing and take of planes, protection of buildings and bridges, monitoring machinery, and harvesting energy from vibrating structures such as bridges and vehicles. |
| FILED | Thursday, January 16, 2020 |
| APPL NO | 16/744652 |
| ART UNIT | 3616 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 21/013 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040922 | Matzger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam Matzger (Ann Arbor, Michigan); Jonathan C. Bennion (Lee, New Hampshire) |
| ABSTRACT | A crystalline composition including an energetic material and hydrogen peroxide, both having observable electron density in a crystal structure of the composition, is provided. Methods of making the crystalline composition are also provided. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023855 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) Original (OR) Class C06B 45/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040924 | Castellanos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jorge Castellanos (LaPlata, Maryland); Demitrios Stamatis (LaPlata, Maryland); Samuel B. Emery (Alexandria, Virginia); David O. Zamor (Port Tobacco, Maryland); Meagan E. Gay (Alexandria, Virginia); George W. McDaniel, Jr. (Alexandria, Virginia); Austin W. Riggins (Knoxville, Tennessee) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jorge Castellanos (LaPlata, Maryland); Demitrios Stamatis (LaPlata, Maryland); Samuel B. Emery (Alexandria, Virginia); David O. Zamor (Port Tobacco, Maryland); Meagan E. Gay (Alexandria, Virginia); George W. McDaniel, Jr. (Alexandria, Virginia); Austin W. Riggins (Knoxville, Tennessee) |
| ABSTRACT | A discrete gradient charge that has a discrete first hollow cylindrical layer of a solid first fuel, which is about 85% by weight fine aluminum powder having a median diameter of about 3.5 microns. There is a discrete second hollow cylindrical layer of a solid second fuel that is about 80% by weight coarse aluminum powder with a median diameter of about 31.0 microns. The fuels have a cured HTPB binder. A pellet of an explosive positioned within the first hollow cylindrical layer provides ignition. The fuel in the charge reacts with the surrounding air or with a hollow cylindrical oxidizer layer, or a combination thereof. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 15/999998 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041445 | Cadman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | John Michael Cadman (Mason, Ohio); David Richard Barnhart (Jefferson, Ohio) |
| ABSTRACT | A valve assembly includes a body including an inlet port, an outlet port, and a flow passage extending therebetween. The flow passage includes a plurality of valve seats in a stepped arrangement between the inlet port and the outlet port. The valve assembly further includes a valve stem positioned within the flow passage. The valve stem includes at least one shaft and a poppet disk positioned at one end of the at least one shaft, and at least one reed petal coupled to the at least one shaft. The poppet disk is engageable with a first valve seat of the plurality of valve seats, and the at least one reed petal is engageable with a second valve seat of the plurality of valve seats. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273300 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/232 (20130101) F02C 9/263 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/443 (20130101) F16K 15/028 (20130101) F16K 15/148 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/7891 (20150401) Y10T 137/87394 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041461 | Beach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Eric Beach (Coventry, Connecticut); Jorge I. Farah (Hartford, Connecticut) |
| ABSTRACT | A system for limiting deflection of an exhaust sidewall liner on a variable geometry exhaust duct uses a spacer and a T-bolt. The system connects the exhaust sidewall liner to the static structure on a variable geometry exhaust duct. The spacer includes a chimney having a first side and a second side opposite of the first side, an aperture extending from the first side to the second side, a flange disposed on the first side, and at least one anti-rotation tab disposed on the second side near an edge of the second side. The T-bolt includes an elongated shaft that extends along an axis and having a diameter, and a head having at least one straight edge connected to an end of the shaft. The at least one straight edge engages with the anti-ration tab, thereby preventing rotation of the stud T-bolt about the axis. |
| FILED | Thursday, February 15, 2018 |
| APPL NO | 15/897902 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/28 (20130101) Jet-propulsion Plants F02K 1/822 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/31 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/21 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041464 | Michael et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | James B. Michael (Ames, Iowa); Travis R. Sippel (Ames, Iowa) |
| ABSTRACT | Apparatus, systems, and methods for enhancing solid propellant performance include seeding combusting energetic material, including solid propellant, with microwave energy at a controlled power and duration. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 15/452531 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0058 (20130101) C06B 21/0066 (20130101) Jet-propulsion Plants F02K 9/24 (20130101) F02K 9/95 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041528 | Colin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | Cummins Inc. (Columbus, Indiana) |
| INVENTOR(S) | Julie Anne Colin (Columbus, Indiana); Nathan E. Coulombe (Greenwood, Indiana); David E. Koeberlein (Columbus, Indiana) |
| ABSTRACT | A main bearing cap having a bearing cap body defining a vertical centerline, the bearing cap body having a top surface opposite a bottom surface, a pair of upper protruding parts and a pair of lower protruding parts that extend in a horizontal direction that is orthogonal to a longitudinal axis of a crankshaft, and a pair of posts that extend between the upper and the lower protruding parts. Each of the posts having a profiled side surface that is recessed to a profiled surface depth to reduce contact pressure and fretting between the bottom surface of the bearing cap and a joint surface of a bulkhead of a cylinder block when the parts are assembled. The profiled side surfaces also reduce the stiffness of the bearing cap to match more closely that of the cylinder block and direct load or force towards a centerline of the bearing cap. |
| FILED | Wednesday, January 08, 2020 |
| APPL NO | 16/737343 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 17/02 (20130101) F16C 33/046 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041701 | Moy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Leon Moy (Verona, New Jersey); Viral Panchal (Parlin, New Jersey); Pasquale Carlucci (Fair Lawn, New Jersey) |
| ABSTRACT | The present invention is directed to composite munition cases that burn without significant residue, rugged enough to withstand rough handling, and provides for additional burn rate control over current state of the art metal and combustible munition cases. The munition cases disclose herein utilizes combustible composite materials having an inner and outer walls connected by support structures. The support structures can be radial walls or honeycomb shaped cells. In another embodiment wedge elements assembled into a cylindrical munition case is also proposed. Exemplary composite materials include felted fiber, foam celluloid and polystyrene. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502159 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041702 | Vasudevan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/691715 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) Original (OR) Class F42B 15/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041704 | Ellis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael E. Ellis (Lake Hopatcong, New Jersey); Michael V. Bruno (Chatham, New Jersey); Deepak Kapoor (Rockaway, New Jersey); Tony F. Zahrah (Fairfax Station, Virginia); Roderick Rowland (Fairfax, Virginia); Steven C. Lawver (Sterling, Virginia) |
| ABSTRACT | A method for preparing a composite projectile body with preformed fragments precisely embedded within the walls of the projectile body. The process utilizes a combination of additive manufacturing and advanced powder metallurgy fabrication techniques. Specifically a skeletal structure or prefabricated cage body is filled with preformed fragments. The cage structure may be situated on a mandrel or tool inside a container. The container is filled with metal powder, degassed under vacuum, and sealed. The canister is then subjected to heat and pressure to consolidate the powder to full density. The canister is then removed and the compacted billet product is further machined to obtain a desired projectile body. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 15/658974 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/15 (20130101) B22F 3/24 (20130101) B22F 7/08 (20130101) B22F 2003/247 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/32 (20130101) Original (OR) Class F42B 33/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041754 | Ifarraguerri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | Augie Ifarraguerri (Arlington, Virginia); Brian Gorin (Setauket, New York); J. Frank Camacho (Albuquerque, New Mexico); Noah Christian (San Diego, California); Robert Rice (Simi Valley, California) |
| ABSTRACT | A system and process scans a target area at a distance of 3-30 m for one or more materials. Scanning is performed by a coherent transmit beam aimed with the help of a thermal camera. The active source of the beam is a supercontinuum (SC) laser. The transmitted source beam is modulated by a high-speed Fourier-transform spectrometer prior to interaction with the target. Target reflected source beam is detected by an infrared detector, along with a reference portion of the transmitted source beam, as a series of interferograms; passed through a digitizer for digitizing the interferograms; and processed to producing spectrograms, wherein the spectrograms are indicative of one or more materials on the target. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/848922 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class G01J 3/0275 (20130101) G01J 3/4537 (20130101) G01J 2003/423 (20130101) G01J 2003/2813 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 2201/0612 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3528 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041841 | Niemann |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Jeffrey D. Niemann (Fort Collins, Colorado) |
| ABSTRACT | Systems and methods are disclosed to downscale the resolution of a coarse-resolution soil moisture data. Coarse-resolution soil moisture data may include data cells that each represent a geographic region having at least one dimension greater than or equal to 1 km. A plurality of fine-resolution supplemental soil moisture data may be received that includes at least one of soil data, vegetation data, topography data, and climate data. The fine-resolution supplemental soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than or equal to 100 meters. The coarse-resolution soil moisture data may be downscaled to fine-resolution soil moisture data using the plurality of fine-resolution supplemental soil moisture data, the fine-resolution soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than 100 meters. |
| FILED | Wednesday, October 19, 2016 |
| APPL NO | 15/769049 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/246 (20130101) Original (OR) Class Meteorology G01W 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041916 | Pham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Linh M. Pham (Arlington, Massachusetts); Erik M. Thompson (Waltham, Massachusetts); John F. Barry (Cambridge, Massachusetts); Kerry A. Johnson (Somerville, Massachusetts); Danielle A. Braje (Winchester, Massachusetts) |
| ABSTRACT | Applying a bias magnetic field to a solid-state spin sensor enables vector magnetic field measurements with the solid-state spin sensor. Unfortunately, if the bias magnetic field drifts slowly, it creates noise that confounds low-frequency field measurements. Fortunately, the undesired slow drift of the magnitude of the bias magnetic field can be removed, nullified, or cancelled by reversing the direction (polarity) of the bias magnetic field at known intervals. This makes the resulting solid-state spin sensor system suitable for detecting low-frequency (mHz, for example) changes in magnetic field or other physical parameters. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/106802 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0017 (20130101) Original (OR) Class G01R 33/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041990 | Frish |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Harel Frish (Moshav Sede Moshe, Israel) |
| ABSTRACT | A structure for coupling an optical signal between an integrated circuit photonic structure and an external optical fiber is disclosed as in a method of formation. The coupling structure is sloped relative to a horizontal surface of the photonic structure such that light entering or leaving the photonic structure is substantially normal to its upper surface. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 16/669937 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 15/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/1857 (20130101) G02B 6/13 (20130101) G02B 6/30 (20130101) Original (OR) Class G02B 6/34 (20130101) G02B 6/122 (20130101) G02B 6/124 (20130101) G02B 6/132 (20130101) G02B 6/3628 (20130101) G02B 2006/12061 (20130101) G02B 2006/12092 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042056 | Lentz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joshua K. Lentz (Niceville, Florida) |
| ABSTRACT | A system, apparatus, and method include a first display device having a first set of pixels adapted to output light; a second display device having a second set of pixels adapted to output light; a first transparent plate spaced apart from each of the first display device and the second display device. The first transparent plate includes a first set of photonic crystal structures arranged in a first direction and adapted to deviate a first path of the light transmitted from the first and second set of pixels at a first angle. A second transparent plate is spaced apart from the first transparent plate and includes a second set of photonic crystal structures arranged in a second direction different from the first direction and adapted to deviate a second path of the light transmitted through the first transparent plate at a second angle to create a third path of light. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/364872 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13336 (20130101) Original (OR) Class G02F 2202/32 (20130101) Electric Digital Data Processing G06F 3/1446 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 9/3026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042073 | Peng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Cheng Peng (Revere, Massachusetts); Dirk Englund (Brookline, Massachusetts) |
| ABSTRACT | Modulating graphene's optical conductivity with an electrolyte nanopatterning technique reduces or eliminates scattering loss caused by rough edges from etching. This technique uses a resist mask patterned with features as small as 30 nm to shield graphene from ions in an electrolyte. It can provide a carrier density variation of about 1014 cm−2 across a length of just 15 nm. And it can be combined with a technique of growing or transferring graphene on atomically smooth hexagonal boron nitride (hBN) to increase graphene's carrier mobility, e.g., to 10,000 cm2/(V·s) or more. The resulting graphene metamaterials can be used to make voltage-tunable electro-optical devices, such as beam-steering devices, electro-optical switch and modulators, and reconfigurable holograms. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/268566 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/29 (20130101) Original (OR) Class G02F 2202/30 (20130101) G02F 2202/36 (20130101) G02F 2203/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042150 | Hansman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert John Hansman (Cambridge, Massachusetts); Luke Loftis Jensen (Cambridge, Massachusetts); Clement Li (Cambridge, Massachusetts) |
| ABSTRACT | An embodiment includes an apparatus that supports a user to make planning decisions of fuel efficiency of an aircraft versus time of arrival of the aircraft along a flight path. An embodiment of the apparatus accepts input data related to the aircraft. The input data may include (i) flight plan data that includes a flight path of the aircraft, (ii) state of the aircraft along the flight path, (iii) environmental data, and (iv) an aircraft performance model of the aircraft. The apparatus calculates aircraft performance and an objective function for a range of altitudes and speeds as a function of the input data. The apparatus causes a user interface to display aircraft performance contour boundaries and a vertical routing path that meets the objective function to provide graphical representations to support a user's planning decisions. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955127 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/005 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0005 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/20 (20200101) Traffic Control Systems G08G 5/0021 (20130101) G08G 5/0034 (20130101) G08G 5/0039 (20130101) G08G 5/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042631 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sudeep Ghosh (Kirkland, Washington); Jason D. Hiser (Charlottesville, Virginia); Jack W. Davidson (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Sudeep Ghosh (Kirkland, Washington); Jason D. Hiser (Charlottesville, Virginia); Jack W. Davidson (Charlottesville, Virginia) |
| ABSTRACT | According to some illustrative embodiments, a method for blending the data of an execution environment and the data of the protected application includes modifying the data values of the protected application using the values of the execution environment in a semantically-neutral manner or modifying the data values of the execution environment using the values of the protected application in a semantically-neutral manner. In some other embodiments, a computer implemented method for binding an execution environment and a protected application includes: selecting at least one instruction from an instruction set of the protected application; selecting at least one context from within the protected application; assigning a new meaning to the selected at least one instruction for the selected at least one context; transforming a program to use the new meaning for the selected at least one instruction and the selected at least one context; and executing the program with the execution environment that knows the newly assigned selected at least one instruction and selected at least one context. In the preferred embodiments, the execution environment comprises any combination of a process-level virtual machine, a system-level virtual machine, a hypervisor, a simulator, an emulator, or a just-in-time compilation system. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 15/535047 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/53 (20130101) Original (OR) Class G06F 21/54 (20130101) G06F 2009/45591 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042647 | Joyce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Robert A. Joyce (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York) |
| ABSTRACT | An example method includes monitoring execution of one or more applications on a runtime computing system that includes a plurality of processing units, receiving, from the runtime computing system during execution of the applications, monitoring information that includes at least one of function call data or application programming interface call data associated with operations performed by the plurality of processing units during execution of the applications, importing the monitoring information into a risk model, analyzing the monitoring information within the risk model to determine one or more potential vulnerabilities and one or more impacts of the one or more vulnerabilities in the runtime computing system, and outputting, for display in a graphical user interface, a graphical representation of the one or more potential vulnerabilities and the one or more impacts within the risk model. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723097 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/52 (20130101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 11/60 (20130101) G06T 11/206 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042795 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Zhengya Zhang (Ann Arbor, Michigan); Chester Liu (Ann Arbor, Michigan); Phil Knag (Portland, Oregon) |
| ABSTRACT | An information processor is provided that includes an inference module configured to extract a subset of data from information in an input and a classification module configured to classify the information in the input based on the extracted data. The inference module includes a first plurality of convolvers acting in parallel to apply each of N1 convolution kernels to each of N2 portions of the input image in order to generate an interim sparse representation of the input and a second plurality of convolvers acting in parallel to apply each of N3 convolution kernels to each of N4 portions of the interim sparse representation to generate a final sparse representation containing the extracted data. In order to take advantage of sparsity in the interim sparse representation, N3 is greater than N4 to parallelize processing in a non-sparse dimension and/or the second plurality of convolvers comprise sparse convolvers. |
| FILED | Tuesday, June 13, 2017 |
| APPL NO | 15/621797 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3293 (20130101) G06F 9/505 (20130101) G06F 9/5094 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) Original (OR) Class G06N 3/063 (20130101) G06N 3/088 (20130101) G06N 3/0454 (20130101) G06N 3/0472 (20130101) G06N 20/10 (20190101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) Y02D 30/50 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043259 | Wentzlaff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | David Wentzlaff (Princeton Junction, New Jersey); Fei Gao (Princeton, New Jersey); Georgios Tziantzioulis (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, an in-memory computation system is disclosed. The system includes a dynamic random access memory (DRAM) module. The system further includes a memory controller configured to violate a timing specification for the DRAM module and activate multiple rows of the DRAM module in rapid succession to enable bit-line charge sharing. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845644 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/4076 (20130101) G11C 11/4085 (20130101) G11C 11/4091 (20130101) G11C 11/4094 (20130101) Original (OR) Class G11C 29/88 (20130101) Pulse Technique H03K 19/20 (20130101) H03K 19/21 (20130101) H03K 19/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043349 | Roper |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Christopher S. Roper (Oak Park, California) |
| ABSTRACT | Some variations provide an electrochemical solid-state field-emission ion source comprising: (a) an ion conductor comprising a protuberance within a protuberance region, wherein the ion conductor contains mobile ions; (b) a first electrode disposed distally from the ion conductor, wherein the protuberance region is on the same side of the first electrode as the ion conductor; (c) a second electrode in contact with the ion conductor, wherein the second electrode is electrically isolated from the first electrode; and (d) an electrical insulator between the ion conductor and the first electrode. Some variations provide a method of electrochemically emitting ions from a field-emission ion source, comprising: applying an electrode potential between the first electrode and the second electrode; oxidizing or reducing the atoms in the atom reservoir, and transporting the atoms into and through the ion conductor as mobile ions; and emitting the mobile ions from the protuberance. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 16/549210 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 1/90 (20130101) H01J 1/304 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043526 | Vincentsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | David M. Vincentsen (Bethlehem, Pennsylvania); Jonas D. Corl (Bethlehem, Pennsylvania); Thomas A. Mitchell (Northampton, Pennsylvania); Michelle M. Stone (Hellertown, Pennsylvania); Thomas W. Stone (Hellertown, Pennsylvania); Randall C. Veitch (Walnutport, Pennsylvania) |
| ABSTRACT | The present disclosure provides an optoelectronic module. In one aspect, the optoelectronic module includes an insertion member including a housing insert and an imager disposed in the housing insert, and a receiving member including an interposer, a housing disposed on the interposer, and an optoelectronic device electrically connected to said interposer. The housing of the receiving member is configured to engage and receive the housing insert of the insertion member. The optoelectronic device of the receiving member is configured to align with the imager of the insertion member. |
| FILED | Sunday, May 24, 2020 |
| APPL NO | 16/882513 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14618 (20130101) H01L 27/14636 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043604 | Wicks |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Gary Wicks (Fairport, New York) |
| ABSTRACT | A resonant cavity-enhanced infrared photodetector has an absorber layer disposed between a first transparent layer and a second transparent layer within an optical cavity. The first transparent layer and the second transparent layer have a bandgap which is larger by at least 0.1 eV compared to the absorber layer. Since the bandgaps of the first and second layer are increased relative to the bandgap of the absorber layer, generation of dark current is limited to the absorber layer. The band profiles of the layers had been designed in order to avoid carrier trapping. In one embodiment, the conduction and valence band offsets are configured to allow unimpeded flow of photogenerated charge carriers away from the absorber layer. The photodetector may be a photoconductor, or a photodiode having n-type and p-type layers. In some embodiments, an interface between the absorber layer and a transparent layer is compositionally graded. In other embodiments, one of a conduction band and a valence band of the absorber layer is aligned with an opposite band of a transparent layer so that a photogenerated charge carrier can tunnel from one band of the absorber layer into the opposite band of the transparent layer. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/745757 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) H01L 31/105 (20130101) H01L 31/109 (20130101) H01L 31/0224 (20130101) H01L 31/1016 (20130101) H01L 31/02327 (20130101) H01L 31/022408 (20130101) Original (OR) Class H01L 31/035236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043705 | Patrissi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States Government of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Charles J Patrissi (Newport, Rhode Island); Joseph H Fontaine (North Kingstown, Rhode Island); Jian Tan (New York, New York) |
| ABSTRACT | A modified battery cell for simulating failure conditions includes a multiple layer electrical cell. A transistor having a source, a gate, and a drain is positioned in the cell. A controllable voltage source is provided, joined to the gate and source of the transistor. The transistor source is further joined to a first location within said electrical cell multiple layers, and the transistor drain is electrically joined to a second location within said electrical cell multiple layers. Voltage from the controllable voltage source can reduce resistance between said transistor source and said transistor drain for simulating a fault condition between the first location and the second location. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/421626 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/382 (20190101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/425 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 50/20 (20210101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043745 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Old Dominion University Research Foundation (Norfolk, Virginia) |
| ASSIGNEE(S) | OLD DOMINION UNIVERSITY RESEARCH FOUNDATION (Norfolk, Virginia) |
| INVENTOR(S) | Shu Xiao (Norfolk, Virginia); Xianbing Zou (Chengdu, China PRC) |
| ABSTRACT | Resistively loaded dielectric biconical antenna apparatuses, including systems and devices, that may be used to transmit very short electrical pulses (e.g., nanosecond, sub-nanosecond, picosecond, etc.) into tissue non-invasively at energy levels sufficient to invoke biological changes in the tissue. These resistively loaded dielectric biconical antenna apparatuses may include a resistor ring reducing internal reflection and reducing energy loss, as well as delivering longer pulses (e.g. microsecond to millisecond) to tissue. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/273112 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/36178 (20130101) A61N 1/37235 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/16 (20130101) Antennas, i.e Radio Aerials H01Q 9/0485 (20130101) Original (OR) Class H01Q 13/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043747 | Mancewicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven Edward Mancewicz (San Diego, California); David Walker Brock (San Diego, California); Robert Joseph Motyl (Oceanside, California) |
| ABSTRACT | An antenna comprising first and second antenna elements, a center conductor, and a dielectric. The first antenna element is configured to be electrically connected to an outer conductor of a coaxial cable. The center conductor is electrically connected to the second antenna element and configured to be electrically connected to an inner conductor of the coaxial cable. The dielectric is disposed around the center conductor so as to separate the center conductor from the first antenna element. The first antenna element is shaped to gradually surround the dielectric and the center conductor over a length of the first antenna element so as to form a balun, integrated into the first antenna element, that is configured to gradually transform an unbalanced signal in the coaxial cable to a balanced signal that is characteristic of a two-conductor transmission line. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437252 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 13/08 (20130101) H01Q 13/085 (20130101) Original (OR) Class H01Q 15/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043785 | Baker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Colin C. Baker (Alexandria, Virginia); Edward J. Friebele (Cheverly, Maryland); Woohong Kim (Lorton, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | Methods for synthesizing fibers having nanoparticles therein are provided, as well as preforms and fibers incorporating nanoparticles. The nanoparticles may include one or more rare earth ions selected based on fluorescence at eye-safer wavelengths, surrounded by a low-phonon energy host. Nanoparticles that are not doped with rare earth ions may also be included as a co-dopant to help increase solubility of nanoparticles doped with rare earth ions in the silica matrix. The nanoparticles may be incorporated into a preform, which is then drawn to form fiber. The fibers may beneficially be incorporated into lasers and amplifiers that operate at eye safer wavelengths. Lasers and amplifiers incorporating the fibers may also beneficially exhibit reduced Stimulated Brillouin Scattering. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783836 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 2201/34 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 13/04 (20130101) C03C 13/045 (20130101) C03C 14/006 (20130101) C03C 2214/16 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/169 (20130101) H01S 3/176 (20130101) H01S 3/1603 (20130101) H01S 3/06716 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043843 | Rozgic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Dejan Rozgic (Los Angeles, California); Dejan Markovic (Los Angeles, California) |
| ABSTRACT | Many embodiments provide an implant power management unit (IPMU) that includes a reconfigurable active rectifier (AR) for wireless power transfer (WPT), where the AR is configurable to operate in a plurality of different modes of operation, an adaptive load control (ALC) unit that accommodates power delivery with load requirements, where the ALC unit is configured to control AR voltage based upon a desired value, control circuitry that is configured to enable a full bridge rectifier in a regular mode of operation of the AR, a feedback circuit that adaptively generates offset current to compensate for switch delays in at least one active NMOS diode, and a feedback circuit that adaptively generates offset current to compensate switch delays in at least one active PMOS diode. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 16/479540 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3787 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 7/0068 (20130101) H02J 50/10 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11044049 | James et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Justin O. James (San Diego, California); Michael P. Daly (San Diego, California) |
| ABSTRACT | A method and system are discussed for providing Unequal Error Protection (UEP) for heterogeneous multi-service provisioning. A transmitter in a network may determine a current status of the network. The transmitter may adaptively adjust a current asymmetric signal constellation and a current channel Forward Error Correction (FEC) coding rate based on the determined current status of the network, and initiate transmission of multi-service data, using the adaptively adjusted asymmetric signal constellation and the adaptively adjusted FEC coding rate for transmission of the multi-service data, based on hybrid Unequal Error Protection (UEP) transmission. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/724836 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/007 (20130101) Original (OR) Class H04L 1/0026 (20130101) H04L 27/3405 (20130101) H04L 2001/0098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11044549 | Byrne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew S. Byrne (Austin, Texas); Hussein Esfahlani (Lausanne, Switzerland); Andrea Alu (Austin, Texas) |
| ABSTRACT | Supercoupling power dividers are provided, in which acoustic impedance at an acoustic input port matches the combined acoustic impedance at two or more acoustic output ports, and the phase of the input signal matches the combined phases of the two or more acoustic output ports. Methods for achieving impedance matching using a uniform-phase acoustic power divider are also provided. The devices and methods achieve acoustic supercoupling without requiring embedded membranes or resonators. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/702328 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/345 (20130101) H04R 1/2857 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11044811 | Verd |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frederick J Verd (Santee, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Frederick J Verd (Santee, California) |
| ABSTRACT | A high power radiofrequency (RF) capacitor, integrated circuit board/capacitor and methods for manufacture therefor can include a dielectric substrate, and a first metallic layer and a second metallic layer that can be deposited on opposite sides of the dielectric substrate, and a ground plane that can be co-planar with one of the metallic layers. This can establish a broadside coupling capacitance effect between the first metallic layer and the second metallic layer. The first metallic layer and the second metallic layer can have a circular profile when viewed in plan view; alternatively, the first metallic layer and second metallic layer can have a T-shaped profile when viewed in plan view. The desired profile and the desired profile geometry can depend on the design power and operating frequency for the capacitor can depend on whether the capacitor must operate as a series capacitor or a shunt capacitor. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/456534 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 1/0007 (20130101) H03H 2001/0085 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/162 (20130101) Original (OR) Class H05K 1/0216 (20130101) H05K 3/4644 (20130101) H05K 2201/093 (20130101) H05K 2201/098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11040296 | Brigham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Derek Brigham (Carlsbad, New Mexico); Laetitia Delmau (Oak Ridge, Tennessee); David DePaoli (Knoxville, Tennessee) |
| ABSTRACT | A method for extracting rare earth metals (e.g., lanthanides and/or actinides) from aqueous solution, the method comprising: (i) acidifying an aqueous solution containing said rare earth metals with sulfuric acid to result in an acidified aqueous solution containing 1-12 M concentration of sulfuric acid; and (ii) contacting the acidified aqueous solution with an aqueous-insoluble hydrophobic solution comprising a rare earth extractant molecule dissolved in an aqueous-insoluble hydrophobic solvent to result in extraction of one or more of the rare earth metals into the aqueous hydrophobic solution, wherein the rare earth extractant molecule has the following structure: wherein R1, R2, R3, and R4 are independently selected from hydrocarbon groups containing 1-20 carbon atoms, provided that the total carbon atoms in R1, R2, R3, and R4 is at least 12; and R5 and R6 are independently selected from hydrogen atom and hydrocarbon groups containing 1-3 carbon atoms. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407710 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/0288 (20130101) Original (OR) Class B01D 11/0292 (20130101) B01D 2257/60 (20130101) Acyclic or Carbocyclic Compounds C07C 235/04 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040590 | Durham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Jerry L. Durham (Bexley, Ohio); Gaymon M. Davis (Columbus, Ohio); Kurt R. Ramsey (Powell, Ohio); Mark J. Soper (Hilliard, Ohio); Michael Perry (Pataskala, Ohio); Arthur A. Horinek (Powell, Ohio); Kevin A. Chilcote (Columbus, Ohio) |
| ABSTRACT | A method and apparatus for lowering the height of a wheeled vehicle for cargo height constraints during transportation. The rear leaf spring shackle on each side of the vehicle is connected to a sliding frame mount. In the transport configuration, fasteners are removed from the sliding frame mount, and the mount slides forward, rotating the rear leaf spring shackle from a near vertical to a near horizontal position, effectively lowering the height of the vehicle. To return the vehicle to the ride configuration, a screw jack member is attached to the sliding frame mount and a rear attachment point on the vehicle, pulling the sliding frame mount back, aligning attachment points of the mount with the frame member in the original position. The fasteners are reinstalled to lock the sliding frame mount into the ride configuration. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/604216 |
| ART UNIT | 3616 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Vehicle Suspension Arrangements B60G 17/023 (20130101) Original (OR) Class B60G 2202/43 (20130101) B60G 2202/112 (20130101) B60G 2204/47 (20130101) B60G 2204/61 (20130101) B60G 2204/121 (20130101) B60G 2204/4232 (20130101) B60G 2206/601 (20130101) B60G 2300/024 (20130101) B60G 2300/026 (20130101) B60G 2500/30 (20130101) B60G 2800/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040898 | Sant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Gaurav Sant (Oakland, California); Zongsu Wei (Oakland, California); Bu Wang (Oakland, California); Erika Callagon La Plante (Oakland, California); Dante Simonetti (Oakland, California) |
| ABSTRACT | A method includes: (1) using a chelating agent, extracting divalent ions from a brine solution as complexes of the chelating agent and the divalent ions; (2) using a weak acid, regenerating the chelating agent and producing a divalent ion salt solution; and (3) introducing carbon dioxide to the divalent ion salt solution to induce precipitation of the divalent ions as a carbonate salt. Another method includes: (1) combining water with carbon dioxide to produce a carbon dioxide solution; (2) introducing an ion exchanger to the carbon dioxide solution to induce exchange of alkali metal cations included in the ion exchanger with protons included in the carbon dioxide solution and to produce a bicarbonate salt solution of the alkali metal cations; and (3) introducing a brine solution to the bicarbonate salt solution to induce precipitation of divalent ions from the brine solution as a carbonate salt. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431300 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 7/12 (20130101) C01D 7/16 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/442 (20130101) C02F 1/444 (20130101) C02F 1/683 (20130101) Original (OR) Class C02F 2103/08 (20130101) C02F 2103/10 (20130101) C02F 2305/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040928 | Weissman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Jeffrey Weissman (Guilford, Connecticut) |
| ABSTRACT | A process and apparatus for converting an alkane to an olefin. In one embodiment, the process involves oxidative coupling of an alkane, e.g., methane, with an oxidant, such as air, to produce an olefin having twice the number of carbon atoms as the alkane, e.g., ethylene. In another embodiment, the process involves oxidative dehydrogenation of an alkane, e.g., ethane, with an oxidant to form an olefin having the same number of carbon atoms as the alkane, e.g., ethylene. The process involves passing a flow of the oxidant from a first flow passage through a porous medium; diffusing a flow of the alkane from a second flow passage into the porous medium; and contacting the reactant alkane and the oxidant in the presence of a catalyst within the porous medium to produce the olefin. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273234 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) B01J 19/249 (20130101) B01J 19/2415 (20130101) B01J 2219/247 (20130101) B01J 2219/2409 (20130101) B01J 2219/2458 (20130101) Acyclic or Carbocyclic Compounds C07C 2/84 (20130101) Original (OR) Class C07C 5/333 (20130101) C07C 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041164 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Xiaohan Yang (Knoxville, Tennessee); Gerald A. Tuskan (Oak Ridge, Tennessee); Degao Liu (Oak Ridge, Tennessee); Rongbin Hu (Knoxville, Tennessee); Jin-Gui Chen (Oak Ridge, Tennessee); Meng Xie (Knoxville, Tennessee) |
| ABSTRACT | The present disclosure provides methods for increasing drought resistance and heat resistance of a plant. The methods encompass expression of at least one heat shock protein (HSP) from the group consisting of HSP40, HSP60 or HSP70 together with a phosphoenolpyruvate carboxylase (PEPC) comprising an aspartic acid (D) at a position that corresponds to the position 509 of SEQ ID NO: 4, in the plant. In comparison to a plant not manipulated in this manner, the disclosed, genetically-modified, plants display improved drought resistance and heat resistance. Also provided are plants that can be obtained by the method according to the invention, and nucleic acid vectors to be used in the described methods. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/015732 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/8273 (20130101) Original (OR) Class Enzymes C12Y 401/01031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041248 | Laramie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sion Power Corporation (Tucson, Arizona) |
| ASSIGNEE(S) | Sion Power Corporation (Tucson, Arizona) |
| INVENTOR(S) | Michael G. Laramie (Tucson, Arizona); Yuriy V. Mikhaylik (Tucson, Arizona); James A. Phipps (Tucson, Arizona); Veronika G. Viner (Tucson, Arizona) |
| ABSTRACT | Articles and methods for forming ceramic/polymer composite structures for electrode protection in electrochemical cells, including rechargeable lithium batteries, are presented. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953734 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/02 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/0407 (20130101) H01M 4/0414 (20130101) H01M 4/0421 (20130101) H01M 4/0426 (20130101) H01M 4/0428 (20130101) H01M 4/622 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 50/46 (20210101) H01M 50/403 (20210101) H01M 50/446 (20210101) H01M 50/449 (20210101) H01M 2004/021 (20130101) H01M 2300/0068 (20130101) H01M 2300/0082 (20130101) H01M 2300/0088 (20130101) H01M 2300/0091 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041389 | Lacy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Benjamin Paul Lacy (Greer, South Carolina); Victor John Morgan (Simpsonville, South Carolina) |
| ABSTRACT | A hot gas path component of an industrial machine includes an adaptive cover for a cooling pathway. The component and adaptive cover are made by additive manufacturing. The component includes an outer surface exposed to a working fluid having a high temperature; an internal cooling circuit; and a cooling pathway in communication with the internal cooling circuit and extending towards the outer surface. The adaptive cover is positioned in the cooling pathway at the outer surface. The adaptive cover may include a heat transfer enhancing surface at the outer surface causing the adaptive cover to absorb heat faster than the outer surface. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 15/609576 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 5/04 (20130101) B22F 5/04 (20130101) B22F 5/04 (20130101) B22F 5/10 (20130101) B22F 7/062 (20130101) B22F 10/20 (20210101) B22F 2003/247 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/186 (20130101) Original (OR) Class F01D 5/187 (20130101) F01D 9/041 (20130101) F01D 9/065 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/30 (20130101) F05D 2230/31 (20130101) F05D 2240/11 (20130101) F05D 2240/81 (20130101) F05D 2260/202 (20130101) F05D 2270/3032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041436 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Russell B. Jones (North Palm Beach, Florida); Joseph D. Brostmeyer (Jupiter, Florida); Justin T. Cejka (Palm Beach Gardens, Florida); John E. Ryznic (Jupiter, Florida) |
| ABSTRACT | A process for retrofitting an industrial gas turbine engine of a power plant where an old industrial engine with a high spool has a new low spool with a low pressure turbine that drives a low pressure compressor using exhaust gas from the high pressure turbine, and where the new low pressure compressor delivers compressed air through a new compressed air line to the high pressure compressor through a new inlet added to the high pressure compressor. The old electric generator is replaced with a new generator having around twice the electrical power production. One or more stages of vanes and blades are removed from the high pressure compressor to optimally match a pressure ratio split. Closed loop cooling of one or more new stages of vanes and blades in the high pressure turbine is added and the spent cooling air is discharged into the combustor. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 16/301560 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) F01D 17/14 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/00 (20130101) F02C 3/13 (20130101) Original (OR) Class F02C 6/00 (20130101) F02C 7/18 (20130101) F02C 9/18 (20130101) F02C 9/22 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/76 (20130101) F05D 2230/80 (20130101) F05D 2240/35 (20130101) F05D 2260/202 (20130101) F05D 2260/211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041795 | Xi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| INVENTOR(S) | Wenze Xi (Ellicott City, Maryland); Rongli Geng (Yorktown, Virginia); Carl Zorn (Yorktown, Virginia); Brian J. Kross (Yorktown, Virginia); Andrew G. Weisenberger (Yorktown, Virginia); Jack McKisson (Williamsburg, Virginia); John McKisson (Newport News, Virginia) |
| ABSTRACT | A reflective laser-based particle detector for detecting contamination particles moving through a vacuum. Laser light is directed through a vacuum access window in the containment vessel and toward a reflective surface on an inner surface opposite the window. A photonic detector is positioned to monitor reflected laser from the opposite inner surface inside the vessel and is capable of detecting perturbations of the reflected light. The system makes use of optical interferometry techniques embodied as a photonic integrated circuit to detect the particles. The reflective laser-based system can be placed entirely outside the vacuum thereby avoiding the need for breaking the vacuum environment to check for accumulation of contaminant particles. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657295 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0211 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041803 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | William Green (Yorktown Heights, New York); Matthias Dittberner (Neustrelit, Germany); Chi Xiong (Yorktown Heights, New York); Eric Zhang (Yorktown Heights, New York); Gerard Wysocki (Princeton, New Jersey) |
| ABSTRACT | A generalized feed-forward method for accurate tunable laser absorption spectroscopy includes generating a laser beam. The generated laser beam is directed down a reference path and a test/sample path. One or more parameters are extracted from the reference path. The one or more parameters, extracted from the reference path, are used as feed-forward, to adjust spectral analysis of the test/sample path to detect a composition and/or concentration of an analyte gas within the test/sample path. The extraction of the one or more parameters from the reference path and the spectral analysis of the test/sample path are performed substantially concurrently. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/364544 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) Original (OR) Class G01N 21/255 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042132 | Fan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Xiaoyuan Fan (Richland, Washington); Xinya Li (Richland, Washington); Emily L. Barrett (Richland, Washington); Qiuhua Huang (Richland, Washington); James G. O'Brien (Richland, Washington); Renke Huang (Richland, Washington); Zhangshuan Hou (Richland, Washington); Ruisheng Diao (Richland, Washington) |
| ABSTRACT | Techniques and apparatuses are described that enable transformative Remedial Action Scheme (RAS) analyses and methodologies for a bulk electric power system, including methods of designing, reviewing, revising, testing, implementing, verifying, or validating a RAS. An improved RAS improves operation of the power system, including performance, reliability, control, and asset utilization. The example methodologies discussed—also referred to as a transformative Remedial Action Scheme tool (TRAST)—provide an end-to-end solution for adaptively setting RAS parameters based on realistic and near real-time operation conditions to improve power grid reliability and grid asset utilization, by leveraging utility data analysis and employing dynamic simulations and machine learning to significantly simplify and shorten the entire RAS process. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/435352 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/042 (20130101) Original (OR) Class G05B 13/0265 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 40/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/008 (20130101) H02J 3/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042988 | Wantuch et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Andrew C. Wantuch (Albuquerque, New Mexico); Kyle Saxberg (Mountain View, California); Edward Steven Jimenez, Jr. (Albuquerque, New Mexico); Jaxon Gittinger (Albuquerque, New Mexico); Srivathsan Koundinyan (Highland Park, New Jersey) |
| ABSTRACT | Illustrative embodiments are directed to a method and apparatus for evaluating boundary detection in an image. A processed image is received, wherein a detected boundary of an image of an object is identified in the processed image. A Radon transform is applied to the processed image for a plurality of angles to form a processed image histogram corresponding to the detected boundary for each of the plurality of angles. The processed image histogram for each of the plurality of angles and a corresponding ground truth histogram for each of the plurality of angles is normalized to provide a normalized processed image histogram and a normalized ground truth histogram for each of the plurality of angles, wherein the ground truth histogram corresponds to a ground truth boundary of the object for a corresponding angle. An indication of the edges of the normalized processed image histogram for each of the plurality of angles is plotted to form a boundary detection evaluation visualization. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/424264 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/13 (20170101) Original (OR) Class G06T 7/162 (20170101) G06T 7/168 (20170101) G06T 2207/10012 (20130101) G06T 2207/20072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043308 | Lahoda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WESTINGHOUSE ELECTRIC COMPANY, LLC (Cranberry Township, Pennsylvania); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Edward J. Lahoda (Edgewood, Pennsylvania); Peng Xu (Columbia, South Carolina); Robert Oelrich (Columbia, South Carolina); Kumar Sridharan (Madison, Wisconsin); Benjamin Maier (Waunakee, Wisconsin); Greg Johnson (Madison, Wisconsin) |
| ABSTRACT | A method is described for forming duplex layers including an interlayer and a corrosion resistant boundary layer on a nuclear fuel rod cladding tube for use in a water cooled nuclear reactor. The method includes forming, by thermal deposition or physical vapor deposition, on the exterior of a substrate, an inner interlayer with Mo, Ta, W or Nb or other particles, and forming, by thermal deposition or physical vapor deposition, on the interlayer, an outer corrosion resistant layer with particles selected from the group consisting of Cr, a Cr alloy, and combinations thereof. The interlayer prevents eutectic formation between the corrosion resistant layer and the substrate. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/722167 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) C23C 14/34 (20130101) C23C 24/08 (20130101) C23C 24/087 (20130101) C23C 28/021 (20130101) C23C 28/023 (20130101) Nuclear Reactors G21C 3/07 (20130101) Original (OR) Class G21C 3/20 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043309 | Nygaard et al. |
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| FUNDED BY |
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| APPLICANT(S) | BWXT Technical Services Group, Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | BWXT Technical Services Group, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Erik T. Nygaard (Lynchburg, Virginia); Peter L. Angelo (Oak Ridge, Tennessee); Scott B. Aase (Aiken, South Carolina) |
| ABSTRACT | The present invention relates generally to the field of compensation methods for nuclear reactors and, in particular to a method for fail-safe reactivity compensation in solution-type nuclear reactors. In one embodiment, the fail-safe reactivity compensation method of the present invention augments other control methods for a nuclear reactor. In still another embodiment, the fail-safe reactivity compensation method of the present invention permits one to control a nuclear reaction in a nuclear reactor through a method that does not rely on moving components into or out of a reactor core, nor does the method of the present invention rely on the constant repositioning of control rods within a nuclear reactor in order to maintain a critical state. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/679721 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 1/24 (20130101) G21C 3/24 (20130101) G21C 7/30 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043335 | Wheeler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Lance Michael Wheeler (Wheat Ridge, Colorado); Rachelle Rosemarie Ihly (Parker, Colorado); Noah James Stanton (Denver, Colorado); Jeffrey Lee Blackburn (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes an active layer and a first charge transport layer, where the first charge transport layer includes a first layer and a second layer, the first layer is in contact with the second layer, the second layer is positioned between the first layer and the active layer, the first layer comprises a first carbon nanostructure, and the second layer includes a second carbon nanostructure. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976108 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) E06B 2009/2417 (20130101) E06B 2009/2476 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2063 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) H01L 51/0036 (20130101) H01L 51/0043 (20130101) H01L 51/0048 (20130101) H01L 51/445 (20130101) H01L 51/4226 (20130101) H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043336 | Voelker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MILTEC CORPORATION (Stevensville, Maryland) |
| ASSIGNEE(S) | Miltec Corporation (Stevensville, Maryland) |
| INVENTOR(S) | Gary Voelker (Bumpass, Virginia); John Arnold (Pittstown, New Jersey); Joseph Fasolo (Edgewood, Maryland) |
| ABSTRACT | A process for manufacturing an electrode utilizing electron beam (EB) or actinic radiation to cure the electrode binder is provided. A process is also disclosed for mixing specific actinic or EB radiation curable polymer precursors with electrode solid particles to form an aqueous mixture, application of the mixture to an electrode current collector, followed by the application of actinic or EB radiation to the current collector for curing the polymer, thereby binding the electrode binder to the current collector. Lithium ion batteries, electric double layer capacitors, and components produced therefrom are also provided. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/130284 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/28 (20130101) H01G 11/48 (20130101) Original (OR) Class H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/139 (20130101) H01M 4/0404 (20130101) H01M 4/622 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043370 | Denis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Elizabeth Denis (Richland, Washington); Brian Dockendorff (Kennewick, Washington); Robert Ewing (Kennewick, Washington); Eric Wilcox Freeburg (Minneapolis, Minnesota); Kelsey Morrison (Richland, Washington); Megan Nims (Richland, Washington); Blandina Valenzuela (Richland, Washington) |
| ABSTRACT | Disclosed herein are embodiments of a system for selectively ionizing samples that may comprise a plurality of different analytes that are not normally detectable using the same ionization technique. The disclosed system comprises a unique split flow tube that can be coupled with a plurality of ionization sources to facilitate using different ionization techniques for the same sample. Also disclosed herein are embodiments of a method for determining the presence of analytes in a sample, wherein the number and type of detectable analytes that can be identified is increased and sensitivity and selectivity are not sacrificed. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/860548 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/282 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043679 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ESS TECH, INC. (Portland, Oregon) |
| ASSIGNEE(S) | ESS TECH, INC. (Portland, Oregon) |
| INVENTOR(S) | Craig E. Evans (West Linn, Oregon); Yang Song (West Linn, Oregon); Jeffrey Chen (Portland, Oregon) |
| ABSTRACT | An electrode for use in an all-iron redox flow battery is provided. In one example, the electrode may include a plastic mesh; and a coating on the plastic mesh. The coating may be a hydrophilic coating or a conductive coating and the electrode may have an electrode reaction potential is less than 0.8V. Further, a method of manufacturing a coated plastic mesh electrode for use in an all-iron redox flow battery is provided. In one example method, the steps include fabricating a plastic mesh, treating the plastic mesh by applying a solvent treatment or a plasma treatment or a mechanical abrasion treatment; coating the plastic mesh with a material selected from: carbon inks, metal oxides, and hydrophilic polymers. |
| FILED | Wednesday, December 30, 2015 |
| APPL NO | 14/984416 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8803 (20130101) Original (OR) Class H01M 4/8817 (20130101) H01M 4/8828 (20130101) H01M 8/18 (20130101) H01M 8/20 (20130101) H01M 8/182 (20130101) H01M 8/184 (20130101) H01M 8/186 (20130101) H01M 8/188 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043684 | Jahnke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Fred C. Jahnke (Rye, New York); Matthew Lambrech (Sherman, Connecticut) |
| ABSTRACT | A carbon dioxide capture system for removing carbon dioxide from a flue gas produced by a combustion power plant. The system includes an electrolyzer cell configured to receive a flue gas comprising carbon dioxide and output a first exhaust stream comprising an enriched flue gas comprising carbon dioxide. The system further includes a fuel cell configured to receive the first exhaust stream and output a second exhaust stream comprising carbon dioxide. The second exhaust stream contains a higher concentration of carbon dioxide than the first exhaust stream. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 15/980291 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/326 (20130101) B01D 2257/504 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/16 (20130101) C01B 2203/066 (20130101) C01B 2203/067 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 15/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0656 (20130101) H01M 8/0668 (20130101) Original (OR) Class H01M 2008/147 (20130101) H01M 2250/10 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/10 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/40 (20200801) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Y02E 60/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/151 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043686 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wei Wang (Kennewick, Washington); Dongping Lu (Richland, Washington); Yuyan Shao (Richland, Washington); Qian Huang (Richland, Washington); Litao Yan (Richland, Washington) |
| ABSTRACT | Described herein are systems and methods of storing and delivering electrical using hydrogen at low-cost and for long-durations. The systems and methods use energy-bearing redox pairs that electrochemically bear energy through decoupled hydrogen and oxygen consumption and/or evolution reactions, which are typically associated with fuel cells. Each species of the energy-bearing redox pair is associated with a standard electrode potential within a water electrolysis voltage window for the electrolyte solution. Electrical energy delivery, hydrogen generation, electrolyte regeneration, or combinations thereof can be performed by logically or physically separated unit operations in a continuous manner, batch manner, or semi-batch manner facilitated by the energy-bearing redox pair. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/988192 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/122 (20130101) B01J 2219/0877 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/73 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/18 (20130101) H01M 8/186 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 8/04276 (20130101) H01M 8/04925 (20130101) H01M 2250/10 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043696 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Liangbing Hu (Hyattsville, Maryland); Eric D. Wachsman (Fulton, Maryland); Yunhui Gong (Clarksville, Maryland); Kun Fu (College Park, Maryland); Wei Luo (College Park, Maryland); Chengwei Wang (College Park, Maryland) |
| ABSTRACT | Metal alloy layers on substrates. The metal-alloy layers (e.g., lithium-metal layers, sodium-metal layers, and magnesium-metal layers) can be disposed on, for example, a solid-state electrolyte material. The metal-alloy layers can be used in, for example, solid-state batteries. A metal alloy layer can be an anode or part of an anode of a solid state battery. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 16/097424 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/40 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/405 (20130101) H01M 4/0407 (20130101) H01M 4/0423 (20130101) H01M 4/0426 (20130101) H01M 4/0428 (20130101) H01M 4/466 (20130101) H01M 4/0471 (20130101) H01M 4/0488 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/661 (20130101) H01M 4/1395 (20130101) H01M 4/5815 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0562 (20130101) H01M 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043815 | Meeker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Richard H. Meeker (Tallahassee, Florida); MD Omar Faruque (Tallahassee, Florida); Juan Ospina (Tallahassee, Florida); Alvi Newaz (Tallahassee, Florida); Emmanuel Collins (Tallahassee, Florida); Griffin Francis (Newton, Massachusetts); Nikhil Gupta (Tallahassee, Florida) |
| ABSTRACT | Devices and methods of allocating distributed energy resources (DERs) to loads connected to a microgrid based on the cost of the DERs are provided. The devices and methods may determine one or more microgrid measurements. The devices and methods may determine one or more real-time electricity prices associated with utility generation sources. The devices and methods may determine one or more forecasts. The devices and methods may determine a cost associated with one or more renewable energy sources within the microgrid. The devices and methods may determine an allocation of the renewable sources to one or more loads in the microgrid. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049785 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) G05B 13/048 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 30/0206 (20130101) G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/003 (20200101) H02J 3/005 (20130101) H02J 3/382 (20130101) Original (OR) Class H02J 3/383 (20130101) H02J 3/386 (20130101) H02J 2203/20 (20200101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 50/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11044169 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dong Chen (Scarsdale, New York); Sameer Kumar (Mountain View, California) |
| ABSTRACT | In a L×M×N 3D torus network of computer nodes, a 2-dimensional plane comprising M×N torus network of nodes mapped into M/2 meshes×2*N torus network of nodes. N can be k*M, k is an integer greater than zero, and M and N are even numbers. Each of M/2 mesh of the 2*N torus is contiguous in the 2D plane. Mapping is performed for each of the L planes of the L×M×N 3D torus network. The M/2 meshes are combined with a remaining torus network dimension comprising L planes, the combining creating another 2*N pattern, wherein an L*M/2×2*N communication pattern is created. Application entities are executed according to the mapped L*M/2×2*N communication pattern. |
| FILED | Monday, January 07, 2019 |
| APPL NO | 16/241128 |
| ART UNIT | 2466 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) H04L 41/145 (20130101) Original (OR) Class H04L 67/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11044423 | Kester |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
| ASSIGNEE(S) | REBELLION PHOTONICS, INC. (Houston, Texas) |
| INVENTOR(S) | Robert Timothy Kester (Friendswood, Texas) |
| ABSTRACT | In one embodiment, an infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including an optical focal plane array (FPA) unit. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. Said optical system and said processing unit can be contained together in a data acquisition and processing module configured to be worn or carried by a person. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530232 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/28 (20130101) G01J 3/0208 (20130101) G01J 3/0232 (20130101) G01J 3/0256 (20130101) G01J 3/0289 (20130101) G01J 3/0297 (20130101) G01J 3/2803 (20130101) G01J 5/02 (20130101) G01J 5/0014 (20130101) G01J 5/026 (20130101) G01J 5/047 (20130101) G01J 5/089 (20130101) G01J 5/0834 (20130101) G01J 2003/104 (20130101) G01J 2003/1217 (20130101) G01J 2003/1221 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3504 (20130101) Optical Elements, Systems, or Apparatus G02B 5/201 (20130101) G02B 5/208 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/209 (20130101) G06K 9/00624 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class H04N 5/2258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11040323 | Talapin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Dmitri V. Talapin (Riverside, Illinois); Hao Zhang (Urbana, Illinois); Vishwas Srivastava (Chicago, Illinois) |
| ABSTRACT | Colloids comprising inorganic nanocrystals dispersed in a molten salt or a liquid metal are provided. The molten salt may comprise an ion which is a Lewis acid or a Lewis base in the presence of the inorganic nanocrystals. Solid composites formed from the colloids are also provided. Methods of using the colloids as media for inducing chemical transformations using the inorganic nanocrystals are also provided. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/772950 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0004 (20130101) B01J 13/06 (20130101) B01J 13/0043 (20130101) B01J 13/0047 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040324 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daeyeon Lee (Wynnewood, Pennsylvania); Junsang Doh (Seoul, South Korea); Miju Kim (Philadelphia, Pennsylvania); Martin F. Haase (Philadelphia, Pennsylvania); Gang Duan (Philadelphia, Pennsylvania) |
| ABSTRACT | Polyelectrolyte microcapsules, and methods for making and using the polyelectrolyte microcapsules, are described. A method of making polyelectrolyte microcapsules includes forming an “interfacial complexation in emulsion” (ICE), wherein a polyelectrolyte “shell” is formed by complexing two different polyelectrolytes together at an interface between two immiscible fluids. Both hydrophilic and hydrophobic materials can be incorporated into the cores and shells of the polyelectrolyte microcapsules. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/097874 |
| ART UNIT | 1699 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 27/72 (20160801) A23L 33/10 (20160801) A23L 33/30 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 8/11 (20130101) A61K 8/84 (20130101) A61K 8/8147 (20130101) A61K 9/5026 (20130101) A61K 9/5031 (20130101) A61K 9/5089 (20130101) A61K 9/5094 (20130101) A61K 2800/56 (20130101) A61K 2800/412 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/06 (20130101) Original (OR) Class B01J 13/10 (20130101) Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 3/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040339 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Angela Dee Mohanty (Clifton Park, New York) |
| ABSTRACT | Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mol %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696186 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 8/04 (20130101) C08F 8/04 (20130101) C08F 8/18 (20130101) C08F 8/24 (20130101) C08F 8/24 (20130101) C08F 8/42 (20130101) C08F 8/42 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 8/44 (20130101) C08F 297/04 (20130101) C08F 297/04 (20130101) C08F 297/04 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) H01M 8/103 (20130101) H01M 8/1023 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040395 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiaochun Li (Manhattan Beach, California); Jiaquan Xu (Los Angeles, California) |
| ABSTRACT | A metal matrix nanocomposite includes: 1) a matrix including one or more metals; and 2) nanostructures uniformly dispersed and stabilized in the matrix at a volume fraction, including those greater than about 3% of the nanocomposite. |
| FILED | Thursday, March 30, 2017 |
| APPL NO | 16/090130 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0025 (20130101) Original (OR) Class B22F 2001/0033 (20130101) Alloys C22C 1/1036 (20130101) C22C 21/06 (20130101) C22C 32/0036 (20130101) C22C 32/0052 (20130101) C22C 32/0063 (20130101) C22C 32/0073 (20130101) C22C 33/0264 (20130101) C22C 47/08 (20130101) C22C 49/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041026 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Mao Chen (Boston, Massachusetts) |
| ABSTRACT | Disclosed are methods, compositions, kits, and reagents to prepare compounds (e.g. polymers and small molecules) via radical reactions by utilizing thermoresponsive and photoresponsive gels. This invention discloses the preparation of polymers via controlled radical polymerizations from an iniferter or initiator, one or more reactant monomer, and a thermoresponsive and photoresponsive gel. Embodiments of the invention show that the polymerization is reversibly activated and/or deactivated by controlling one or more of the following external control stimuli: temperature, light, and catalyst presence. This invention also relates the preparation of Gel-PTH, a heterogeneous thermoresponsive and photoresponsive gel. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 16/080536 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 2/50 (20130101) Original (OR) Class C08F 4/40 (20130101) C08F 293/005 (20130101) C08F 2438/01 (20130101) C08F 2438/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041051 | Youngblood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research University (West Lafayette, Indiana) |
| INVENTOR(S) | Jeffrey Paul Youngblood (West Lafayette, Indiana); Caitlyn Michelle Clarkson (West Lafayette, Indiana); Md Nuruddin (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to a novel method for dispersion of nanocellulose in melt-processed polymers without the introduction of solvent during melt processing. |
| FILED | Wednesday, August 14, 2019 |
| APPL NO | 16/540195 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/005 (20130101) Original (OR) Class C08J 2333/12 (20130101) C08J 2367/04 (20130101) C08J 2371/02 (20130101) C08J 2377/06 (20130101) C08J 2401/02 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) C08L 33/12 (20130101) C08L 71/02 (20130101) C08L 77/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041187 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Brian T. Cunningham (Champaign, Illinois); Yue Zhuo (Champaign, Illinois); Brendan Harley (Urbana, Illinois); Ji Sun Choi (Urbana, Illinois); Thibault Marin (Champaign, Illinois); Yi Lu (Champaign, Illinois) |
| ABSTRACT | A digital assay for a micro RNA (miRNA) or other target analyte in a sample makes use of nanoparticles that absorb light at the resonant wavelength of a photonic crystal (PC). Such nanoparticles locally quench the resonant reflection of light from the PC when present on the surface of the PC. The nanoparticles are functionalized to specifically bind to the target analyte, and the PC surface is functionalized to specifically bind to the nanoparticles that have bound to the target analyte. The sample is exposed to the functionalized nanoparticles, and the individual nanoparticles bound to the PC surface can be identified and counted based on reduced intensity values in the reflected light from the PC. The number of bound nanoparticles that are counted in this way can be correlated to the abundance of the target analyte in the sample. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170111 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041338 | Saive et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Rebecca Saive (Enschede, Netherlands); Harry A. Atwater (South Pasadena, California); Thomas C. R. Russell (Pasadena, California); Michael D. Kelzenberg (Glendale, California); Lucas J. Myers (Stoughton, Wisconsin) |
| ABSTRACT | Systems and methods for transparent materials implementing effectively transparent conductors in accordance with various embodiments of the invention are illustrated. One embodiment includes a window including a first transparent layer of transparent material having a first surface and a second surface, a first plurality of triangular conductors in optical communication with the first transparent layer of glass, wherein each of the first plurality of triangular conductors includes a base side that is parallel to the first surface of the first transparent layer of glass and wherein the first plurality of triangular conductors is configured to redirect a portion of incident light, wherein the portion of incident light travels through both the first surface and the second surface of the first transparent layer of glass. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547511 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6612 (20130101) E06B 3/6715 (20130101) Original (OR) Class E06B 9/24 (20130101) E06B 2009/2417 (20130101) E06B 2009/2464 (20130101) Optical Elements, Systems, or Apparatus G02B 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041759 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Juejun Hu (Newton, Massachusetts); Derek Kita (Cambridge, Massachusetts); Jerome Michon (Cambridge, Massachusetts) |
| ABSTRACT | A method of performing Raman spectroscopy can include guiding a Raman pump beam with an optical fiber, where the Raman pump beam inducing fluorescence in the optical fiber. The beam and the fluorescence are coupled to a photonic integrated circuit (PIC) via the fiber. The beam is used to excite a sample in optical communication with the PIC via evanescent coupling and induces Raman scattering in the sample. The Raman scattering is collected via the PIC, and the Raman pump beam as well as the fluorescence is filtered out from the Raman scattering via the PIC. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/456188 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/0205 (20130101) G01J 3/0218 (20130101) G01J 3/4406 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041764 | Chakrabartty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shantanu Chakrabartty (St. Louis, Missouri); Liang Zhou (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Shantanu Chakrabartty (St. Louis, Missouri); Liang Zhou (St. Louis, Missouri) |
| ABSTRACT | A sensor system for detecting events is provided. The sensor system includes a sensor and a read-out interface. The sensor includes a transducer and a memory device. The transducer detects an event and generates a sensor signal in response to the event. The memory device includes a floating-gate with a sensing interface coupled to the transducer. The sensing interface has an energy barrier that leaks electrons at a predetermined electron leakage rate through Fowler-Nordheim (F-N) tunneling. The sensor signal alters a geometry of the energy barrier to change the electron leakage rate. The read-out interface is communicatively coupled to the memory device and retrieves data stored on the memory device for analysis. The event and a timestamp of the event are identifiable from the stored data. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 16/079848 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/06 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041990 | Frish |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Harel Frish (Moshav Sede Moshe, Israel) |
| ABSTRACT | A structure for coupling an optical signal between an integrated circuit photonic structure and an external optical fiber is disclosed as in a method of formation. The coupling structure is sloped relative to a horizontal surface of the photonic structure such that light entering or leaving the photonic structure is substantially normal to its upper surface. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 16/669937 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 15/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/1857 (20130101) G02B 6/13 (20130101) G02B 6/30 (20130101) Original (OR) Class G02B 6/34 (20130101) G02B 6/122 (20130101) G02B 6/124 (20130101) G02B 6/132 (20130101) G02B 6/3628 (20130101) G02B 2006/12061 (20130101) G02B 2006/12092 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042019 | Simpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Garth Jason Simpson (West Lafayette, Indiana); James Ulcickas (West Lafayette, Indiana); Fengyuan Deng (Watertown, Massachusetts); Changqin Ding (West Lafayette, Indiana) |
| ABSTRACT | A method for imaging a sample, wherein the sample changes a polarization state of light as a function of position, wherein the method includes changing a polarization state of a purely polarized light of an incident light striking a micro-retarder array, thereby inducing a changed polarization state of the polarization state. The micro-retarder array is placed in a rear conjugate focal plane of a microscope. The method additionally includes projecting the changed polarization state of the polarization state into an object plane of the microscope containing the sample. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713838 |
| ART UNIT | 2424 — Cable and Television |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/26 (20130101) G02B 21/367 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10056 (20130101) G06T 2207/20212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042631 | Ghosh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sudeep Ghosh (Kirkland, Washington); Jason D. Hiser (Charlottesville, Virginia); Jack W. Davidson (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Sudeep Ghosh (Kirkland, Washington); Jason D. Hiser (Charlottesville, Virginia); Jack W. Davidson (Charlottesville, Virginia) |
| ABSTRACT | According to some illustrative embodiments, a method for blending the data of an execution environment and the data of the protected application includes modifying the data values of the protected application using the values of the execution environment in a semantically-neutral manner or modifying the data values of the execution environment using the values of the protected application in a semantically-neutral manner. In some other embodiments, a computer implemented method for binding an execution environment and a protected application includes: selecting at least one instruction from an instruction set of the protected application; selecting at least one context from within the protected application; assigning a new meaning to the selected at least one instruction for the selected at least one context; transforming a program to use the new meaning for the selected at least one instruction and the selected at least one context; and executing the program with the execution environment that knows the newly assigned selected at least one instruction and selected at least one context. In the preferred embodiments, the execution environment comprises any combination of a process-level virtual machine, a system-level virtual machine, a hypervisor, a simulator, an emulator, or a just-in-time compilation system. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 15/535047 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/53 (20130101) Original (OR) Class G06F 21/54 (20130101) G06F 2009/45591 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042785 | Cox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Cox (Somerville, Massachusetts); Walter Scheirer (Somerville, Massachusetts); Samuel Anthony (Cambridge, Massachusetts); Ken Nakayama (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | David Cox (Somerville, Massachusetts); Walter Scheirer (Somerville, Massachusetts); Samuel Anthony (Cambridge, Massachusetts); Ken Nakayama (Cambridge, Massachusetts) |
| ABSTRACT | In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classifies based at least in part on the human-weighted loss function. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842101 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) G06K 9/627 (20130101) G06K 9/6263 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042800 | Mars et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cline, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Cline, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Jason Mars (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for implementing an artificially intelligent virtual assistant includes collecting a user query; using a competency classification machine learning model to generate a competency label for the user query; using a slot identification machine learning model to segment the text of the query and label each of the slots of the query; generating a slot value for each of the slots of the query; generating a handler for each of the slot values; and using the slot values to: identify an external data source relevant to the user query, fetch user data from the external data source, and apply one or more operations to the query to generate response data; and using the response data, to generate a response to the user query. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743929 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/3329 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043026 | Fathi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pointivo, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | POINTIVO, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Habib Fathi (Atlanta, Georgia); Daniel L Ciprari (Atlanta, Georgia); Bradden J Gross (Atlanta, Georgia) |
| ABSTRACT | The inventions herein relate generally to improvements in the generation of wireframe renderings derived from 2D and/or 3D data that includes at least one structure of interest in a scene. Such wireframe renderings and similar formats can be used in, among other things, 2D/3D CAD drawings, designs, drafts, models, building information models, augmented reality or virtual reality, and the like. Measurements, dimensions, geometric information, and semantic information generated according to the inventive methods can be accurate in relation to the actual structures. The wireframe renderings can be generated from a combination of a plurality of 2D images and point clouds, processing of point clouds to generate virtual/synthetic views to be used with the point clouds, or from 2D image data that has been processed in a machine learning process to generate 3D data. In some aspects, the wireframe renderings are accurate in relation to the actual structure of interest, automatically generated, or both. |
| FILED | Sunday, January 28, 2018 |
| APPL NO | 15/881795 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 30/13 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 17/05 (20130101) G06T 17/20 (20130101) Original (OR) Class G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043208 | Michelin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cline, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Daniel C. Michelin (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Stefan Larson (Ann Arbor, Michigan); Joseph J. Peper (Ann Arbor, Michigan); Yunqi Zhang (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for intelligently training a subject machine learning model includes identifying new observations comprising a plurality of distinct samples unseen by a target model during a prior training; creating an incremental training corpus based on randomly sampling a collection of training data samples that includes a plurality of new observations and a plurality of historical training data samples used in the prior training of the target model; implementing a first training mode that includes an incremental training of the target model using samples from the incremental training corpus as model training input; computing performance metrics of the target model based on the incremental training; evaluating the performance metrics of the target model against training mode thresholds; and selectively choosing based on the evaluation one of maintaining the first training mode and automatically switching to a second training mode that includes a full retraining of the target model. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180112 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 40/35 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/063 (20130101) Original (OR) Class G10L 2015/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043259 | Wentzlaff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | David Wentzlaff (Princeton Junction, New Jersey); Fei Gao (Princeton, New Jersey); Georgios Tziantzioulis (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, an in-memory computation system is disclosed. The system includes a dynamic random access memory (DRAM) module. The system further includes a memory controller configured to violate a timing specification for the DRAM module and activate multiple rows of the DRAM module in rapid succession to enable bit-line charge sharing. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845644 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/4076 (20130101) G11C 11/4085 (20130101) G11C 11/4091 (20130101) G11C 11/4094 (20130101) Original (OR) Class G11C 29/88 (20130101) Pulse Technique H03K 19/20 (20130101) H03K 19/21 (20130101) H03K 19/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043282 | Vaske et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNVIERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Charles J. Vaske (Santa Cruz, California); Stephen C. Benz (Santa Cruz, California); Joshua M. Stuart (Santa Cruz, California); David Haussler (Santa Cruz, California) |
| ABSTRACT | The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 15/667535 |
| ART UNIT | 3619 — Semiconductors/Memory |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 25/00 (20190201) G16B 40/00 (20190201) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043592 | Naeemi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Azad Naeemi (Atlanta, Georgia); Chenyun Pan (Arlington, Texas) |
| ABSTRACT | An anti-ferromagnetic (AFM) voltage-controlled field effect logic device structure can include an AFM material that extends in a first direction and an input voltage terminal that extends opposite the AFM material. An oxide material can be located between the AFM material and the input voltage terminal. A first spin orbital coupling (SOC) material can extend in a second direction across the AFM material to provide a first SOC channel with a drain voltage terminal at a first end of the first SOC channel and an output voltage terminal at a second end of the first SOC channel that is opposite the first end. A contact can be electrically coupled to the output voltage terminal and configured to electrically couple to a second SOC material extending in the second direction spaced apart from the first SOC material to provide a second SOC channel. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/541564 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/329 (20130101) H01F 10/3268 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78391 (20140902) Original (OR) Class H01L 43/02 (20130101) Pulse Technique H03K 19/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043857 | Krishnasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Jayaraman Krishnasamy (Boxborough, Massachusetts); Martin Hosek (Lowell, Massachusetts); Dennis Poole (East Derry, New Hampshire) |
| ABSTRACT | An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/195174 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/126 (20130101) Gearing F16H 25/20 (20130101) F16H 2025/2081 (20130101) Dynamo-electric Machines H02K 1/146 (20130101) Original (OR) Class H02K 1/278 (20130101) H02K 7/06 (20130101) H02K 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11040061 | Golobish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CYTOSORBENTS CORPORATION (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | CytoSorbents Corporation (Monmouth Junction, New Jersey) |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Monmouth Junction, New Jersey); Tamaz Guliashvili (Monmouth Junction, New Jersey); Pamela O'Sullivan (Monmouth Junction, New Jersey); Andrew Scheirer (Bethlehem, Pennsylvania); Vi Dan (Monmouth Junction, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Monmouth Junction, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, October 21, 2016 |
| APPL NO | 15/769361 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/14 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11041702 | Vasudevan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/691715 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) Original (OR) Class F42B 15/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042800 | Mars et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cline, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Cline, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Jason Mars (Ann Arbor, Michigan); Lingjia Tang (Ann Arbor, Michigan); Michael Laurenzano (Ann Arbor, Michigan); Johann Hauswald (Ann Arbor, Michigan); Parker Hill (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for implementing an artificially intelligent virtual assistant includes collecting a user query; using a competency classification machine learning model to generate a competency label for the user query; using a slot identification machine learning model to segment the text of the query and label each of the slots of the query; generating a slot value for each of the slots of the query; generating a handler for each of the slot values; and using the slot values to: identify an external data source relevant to the user query, fetch user data from the external data source, and apply one or more operations to the query to generate response data; and using the response data, to generate a response to the user query. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743929 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) G06F 16/3329 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043208 | Michelin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cline, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Clinc, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Daniel C. Michelin (Ann Arbor, Michigan); Jonathan K. Kummerfeld (Ann Arbor, Michigan); Kevin Leach (Ann Arbor, Michigan); Stefan Larson (Ann Arbor, Michigan); Joseph J. Peper (Ann Arbor, Michigan); Yunqi Zhang (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for intelligently training a subject machine learning model includes identifying new observations comprising a plurality of distinct samples unseen by a target model during a prior training; creating an incremental training corpus based on randomly sampling a collection of training data samples that includes a plurality of new observations and a plurality of historical training data samples used in the prior training of the target model; implementing a first training mode that includes an incremental training of the target model using samples from the incremental training corpus as model training input; computing performance metrics of the target model based on the incremental training; evaluating the performance metrics of the target model against training mode thresholds; and selectively choosing based on the evaluation one of maintaining the first training mode and automatically switching to a second training mode that includes a full retraining of the target model. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180112 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 40/35 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/063 (20130101) Original (OR) Class G10L 2015/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043857 | Krishnasamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Persimmon Technologies, Corp. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | Persimmon Technologies Corporation (Wakefield, Massachusetts) |
| INVENTOR(S) | Jayaraman Krishnasamy (Boxborough, Massachusetts); Martin Hosek (Lowell, Massachusetts); Dennis Poole (East Derry, New Hampshire) |
| ABSTRACT | An apparatus includes a motor having a rotor; and a stator, where the rotor is located at least partially in a rotor receiving area of the stator, where the stator includes at least one coil winding and teeth, where the at least one coil winding is located on at least some of the teeth, where the teeth include a first set of the teeth and a second set of the teeth, where the teeth of the first set of teeth are longer in a radial direction from the rotor receiving area than the teeth of the second set of teeth. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/195174 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/126 (20130101) Gearing F16H 25/20 (20130101) F16H 2025/2081 (20130101) Dynamo-electric Machines H02K 1/146 (20130101) Original (OR) Class H02K 1/278 (20130101) H02K 7/06 (20130101) H02K 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11040082 | Merlin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia); The United States Government as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Didier Merlin (Decatur, Georgia) |
| ABSTRACT | The present invention relates to methods of treating a patient who has colorectal cancer and to methods of reducing the likelihood that a patient will develop or experience a recurrence of colorectal cancer. The methods comprise a step of introducing, to the patient, an effective amount of an agent that targets an intestinal H+-coupled di/tripeptide transporter (PepT1). Useful compositions including, for example, the tripeptide KPV, vectors encoding such peptides, and cells (e.g., bacterial cells) including them, are also within the scope of the present invention, as are kits including such compositions. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 15/502060 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/655 (20130101) A61K 31/655 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 38/06 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 35/00 (20180101) Peptides C07K 5/0815 (20130101) C07K 5/06026 (20130101) C07K 5/06052 (20130101) C07K 5/06086 (20130101) C07K 5/06165 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11040935 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Beibei Chen (Pittsburgh, Pennsylvania); Rama K. Mallampalli (Pittsburgh, Pennsylvania); Yuan Liu (Pittsburgh, Pennsylvania) |
| ABSTRACT | Described herein are compounds that disrupt the interaction between Fbxo48 and phosphorylated-AMPK. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 16/339534 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Acyclic or Carbocyclic Compounds C07C 215/08 (20130101) C07C 215/18 (20130101) C07C 217/34 (20130101) Original (OR) Class Heterocyclic Compounds C07D 205/04 (20130101) C07D 217/04 (20130101) C07D 311/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043143 | Ratcliffe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia); Alan Bao-Chan Dang (Orange, California) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Mark B. Ratcliffe (Piedmont, California); Liang Ge (Foster City, California); Alan Bao-Chan Dang (Orange, California) |
| ABSTRACT | A method and system are presented for performing virtual surgery simulations. The computer system includes a processor and a memory. The method includes receiving user input from a user via a user interface. The user input includes input representing surgical operations or non-surgical invasive procedures. The method also includes processing the user input and utilizing the input to generate or modify a computational model. The method also includes running simulations using the computational model in accordance with the user input. After running the simulations, the method further includes determining results from the simulations. The results correspond to probable effects or outcomes of performing real life surgical operations or non-surgical invasive procedures corresponding to the user input. Last, the method includes presenting the results to the user via the user interface. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 15/424070 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 9/00 (20130101) G09B 23/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11041539 | Myers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | W. Neill Myers (Huntsville, Alabama); Robert E. Berry (Madison, Alabama); Frederick Scott Gant (Huntsville, Alabama); Jeffrey Lee Lindner (Madison, Alabama); John S. Townsend (Union Grove, Alabama) |
| ABSTRACT | A bi-directional damping system generates damping forces in two opposing directions. A shaft has a plurality of bi-directional damping modules fixedly coupled thereto. Each module includes a fluid-filled variable-volume first chamber including at least one port through which fluid can flow based on changes in volume of the first chamber, and a fluid-filled variable-volume second chamber including at least one port through which fluid can flow based on changes in volume of the second chamber. The first chamber and second chamber are fluidically isolated from one another. A fluid-filled spacer chamber is coupled to adjacent ones of the modules. The spacer chamber includes at least one venting port through which fluid can flow based on pressure in the spacer chamber. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 16/948884 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 9/049 (20130101) F16F 9/0418 (20130101) F16F 15/0232 (20130101) Original (OR) Class F16F 2222/126 (20130101) F16F 2230/32 (20130101) F16F 2232/08 (20130101) F16F 2234/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11042443 | Mestar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lini Mestar (Pasadena, California); David C Foor (Pasadena, California); William D Whitaker (Pasadena, California) |
| ABSTRACT | Systems and methods for fault tolerant computing in accordance with various embodiments of the invention are disclosed. Fault tolerant computer systems in accordance with a number of embodiments of the invention include multiple processing systems supervised by a Fault Management Unit (FMU). The FMU can build a representation of the state of all of the multiple processing systems and then determines which of the processing systems to utilize to perform a particular function based upon this state representation. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 16/653544 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1417 (20130101) Original (OR) Class G06F 11/2028 (20130101) G06F 11/2242 (20130101) G06F 11/3013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11043311 | Thomsen, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Donald L. Thomsen, III (Yorktown, Virginia); William Girard (Newport News, Virginia) |
| ABSTRACT | A radiation shielded vault structure includes a rigid outer structure comprising a plurality of rigid structural components that are interconnected at elongated joints to define an interior space. The structural components include a layer of lower atomic number (Z) material such as aluminum alloy and one or more layers of higher atomic number (Z) material titanium and/or tantalum. The vault structure may include radiation shield members extending along the elongated joints to provide radiation shielding at the elongated joints. The shield members comprise a higher atomic number (Z) material such as titanium or tantalum. The rigid structural components may comprise plate members that are interconnected along side edges thereof. End plates may be attached to the plate members to close off the interior space. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/578981 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/085 (20130101) Original (OR) Class G21F 1/125 (20130101) G21F 7/00 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/00 (20130101) H02S 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11041143 | Mandadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Kranthi K. Mandadi (Weslaco, Texas); Sonia C. Irigoyen (Weslaco, Texas); T. Erik Mirkov (Harlingen, Texas) |
| ABSTRACT | Numerous plant microbes, including the vascular-limited Candidatus spp.—causal agents of citrus greening and potato zebra chip diseases—are non-culturable. The present disclosure relates, according to some embodiments, to compositions, methods and systems for culturing such organisms. For example, the present disclosure relates to methods for culturing, propagating, and characterizing fastidious vascular-colonizing microbes using a hairy root system (e.g., in vitro, in planta). The present disclosure relates, in some embodiments, to methods for cultivating a fastidious plant microbe including: contacting a plant (e.g., a tomato plant, a potato plant, a citrus plant) colonized by a fastidious plant microbe (e.g., Xylella fastidiosa, Candidatus Liberibacter spp.) with a suspension of R. rhizogenes under conditions that permit induction of hairy roots colonized with the fastidious plant microbe, and propagating the colonized microbial hairy roots. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353645 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 4/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class C12N 5/04 (20130101) C12N 15/8241 (20130101) C12N 2502/70 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/689 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/195 (20130101) G01N 2333/415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11043592 | Naeemi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Azad Naeemi (Atlanta, Georgia); Chenyun Pan (Arlington, Texas) |
| ABSTRACT | An anti-ferromagnetic (AFM) voltage-controlled field effect logic device structure can include an AFM material that extends in a first direction and an input voltage terminal that extends opposite the AFM material. An oxide material can be located between the AFM material and the input voltage terminal. A first spin orbital coupling (SOC) material can extend in a second direction across the AFM material to provide a first SOC channel with a drain voltage terminal at a first end of the first SOC channel and an output voltage terminal at a second end of the first SOC channel that is opposite the first end. A contact can be electrically coupled to the output voltage terminal and configured to electrically couple to a second SOC material extending in the second direction spaced apart from the first SOC material to provide a second SOC channel. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/541564 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/329 (20130101) H01F 10/3268 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78391 (20140902) Original (OR) Class H01L 43/02 (20130101) Pulse Technique H03K 19/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11043603 | Delaunay |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL LABORATORIES LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Pierre-Yves Delaunay (Santa Monica, California) |
| ABSTRACT | An infrared detector and a method for manufacturing it are disclosed. The infrared detector contains an absorber layer responsive to infrared light, a barrier layer disposed on the absorber layer, a plurality of contact structures disposed on the barrier layer; and an oxide layer disposed above the barrier layer and between the plurality of the contact structures, wherein the oxide layer reduces the dark current in the infrared detector. The method disclosed teaches how to manufacture the infrared detector. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212789 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/0216 (20130101) Original (OR) Class H01L 31/0224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11041754 | Ifarraguerri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | Augie Ifarraguerri (Arlington, Virginia); Brian Gorin (Setauket, New York); J. Frank Camacho (Albuquerque, New Mexico); Noah Christian (San Diego, California); Robert Rice (Simi Valley, California) |
| ABSTRACT | A system and process scans a target area at a distance of 3-30 m for one or more materials. Scanning is performed by a coherent transmit beam aimed with the help of a thermal camera. The active source of the beam is a supercontinuum (SC) laser. The transmitted source beam is modulated by a high-speed Fourier-transform spectrometer prior to interaction with the target. Target reflected source beam is detected by an infrared detector, along with a reference portion of the transmitted source beam, as a series of interferograms; passed through a digitizer for digitizing the interferograms; and processed to producing spectrograms, wherein the spectrograms are indicative of one or more materials on the target. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/848922 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class G01J 3/0275 (20130101) G01J 3/4537 (20130101) G01J 2003/423 (20130101) G01J 2003/2813 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 2201/0612 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3528 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11042832 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Naomi Miller (Washington, District of Columbia); Robert E. Dixon, Jr. (Washington, District of Columbia); Nii-Kwashie Aryeetey (Washington, District of Columbia) |
| ABSTRACT | Systems and methods for generating and implementing a household customer database are disclosed. In one aspect, a method for processing items comprises receiving a first item to be delivered and identifying data corresponding to one or more of a source information and destination information of the first item. The method further comprises identifying secondary information of the first item, storing the source, destination, and secondary information in a database, creating associations between the source, destination, and secondary information, receiving a request to analyze information stored and associated in the database, determining whether the database comprises information necessary to perform the requested analysis, identifying if additional information is needed to perform the requested analysis, updating the secondary information associations to include the additional information if needed to perform the requested analysis, and analyzing the information stored and associated in the database based on the received analysis request or query. |
| FILED | Tuesday, December 12, 2017 |
| APPL NO | 15/839721 |
| ART UNIT | 3688 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0838 (20130101) G06Q 10/08355 (20130101) Original (OR) Class G06Q 2220/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 22, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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