FedInvent Patents
Patent Details for Tuesday, June 29, 2021
This page was updated on Saturday, July 17, 2021 at 01:24 AM GMT
Department of Health and Human Services (HHS)
| US 11044896 | Brown et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Brian Brown (New York, New York); Judith Agudo (New York, New York) |
| ABSTRACT | This invention relates to a transgenic non-human mammal whose genome comprises a polynucleotide sequence encoding a T cell receptor that is specific to a fluorescent protein, where the T cell of the non-human mammal comprises the T cell receptor. The present invention also relates to an isolated T cell from the transgenic non-human mammal of the present invention, an isolated T cell comprising an expression construct comprising a polynucleotide sequence that encodes a T cell receptor that is specific to a fluorescent protein, methods of making transgenic non-human mammals comprising T cell receptors that are specific to a fluorescent protein, a method of depleting cells in a non-human mammal using isolated T cells that encode a T cell receptor that is specific to a target protein, and a method of characterizing a T cell response to an agent. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 15/021026 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2217/30 (20130101) A01K 2227/105 (20130101) A01K 2267/0387 (20130101) A01K 2267/0393 (20130101) Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 2333/70503 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045121 | Esenaliev et al. |
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| APPLICANT(S) | Noninvasix, Inc. (Galveston, Texas); The Board of Regents of The University of Texas (Austin, Texas) |
| ASSIGNEE(S) | Noninvasix, Inc. (Galveston, Texas) |
| INVENTOR(S) | Rinat Esenaliev (League City, Texas); Donald S. Prough (Galveston, Texas); Yuriy Petrov (Galveston, Texas); Irene Petrov (Galveston, Texas); George Saade (Houston, Texas); Gayle L. Olson (Galveston, Texas); Tommy G. Cooper (Friendswood, Texas) |
| ABSTRACT | Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary. |
| FILED | Tuesday, January 22, 2019 |
| APPL NO | 16/253678 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) A61B 5/742 (20130101) A61B 5/1459 (20130101) A61B 5/1464 (20130101) A61B 5/6814 (20130101) A61B 5/6875 (20130101) A61B 5/14542 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 5/14553 (20130101) A61B 2560/0425 (20130101) A61B 2562/0271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045134 | Leuthardt |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Eric Leuthardt (St. Louis, Missouri) |
| ABSTRACT | A brain computer interface (BCI) system includes an electroencephalogram (EEG) headset and a computing device communicatively coupled to the EEG headset. The computing device includes a memory, a processor and a display device. The memory stores instructions that, when executed by the processor, cause the processor to monitor, using the EEG headset, current extrinsic network activity and current intrinsic network activity of a patient, generate a current depression index based on the relationship between the current extrinsic network activity and the current intrinsic network activity, and display, on the display device, a representation of the relationship between the current depression index and a baseline depression index previously generated for the patient. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 15/410411 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/165 (20130101) A61B 5/316 (20210101) Original (OR) Class A61B 5/369 (20210101) A61B 5/4848 (20130101) A61B 5/7405 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045167 | Cabrera-Munoz et al. |
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| APPLICANT(S) | Nestor E. Cabrera-Munoz (Los Angeles, California); Payam Eliahoo (Los Angeles, California); Koping K. Shung (Monterey Park, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Nestor E. Cabrera-Munoz (Los Angeles, California); Payam Eliahoo (Los Angeles, California); Koping K. Shung (Monterey Park, California) |
| ABSTRACT | An intraluminal forward-looking image producing device and associated methods of use and construction is disclosed. In particular, the device of the present invention is an intraluminal forward-looking intravascular ultrasound (IVUS) image producing device. The invention also encompasses methods of using the intraluminal forward-looking intravascular ultrasound (IVUS) image producing device to image objects and material in a forward direction. The disclosed methods also involve manufacturing the intraluminal forward-looking intravascular ultrasound (IVUS) image producing device including the piezoelectric transducer. The resulting device is an elongated body configured to fit within the lumen of a vessel and having an imaging sensor located on the distal end of the elongated body configured to image objects and material in a forward direction. The method further involves inserting the intraluminal forward-looking intravascular ultrasound (IVUS) image producing device into a lumen of a vessel, and imaging objects or material in a forward direction. The methods of the present invention are particularly useful in vascular diagnostic and therapeutic procedures when the vessel has been completely blocked by plaque and imaging of the occlusion is required. |
| FILED | Monday, July 13, 2015 |
| APPL NO | 15/325547 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) Original (OR) Class A61B 8/445 (20130101) A61B 8/461 (20130101) A61B 8/0891 (20130101) A61B 8/4494 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045428 | Kim et al. |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Anthony J. Kim (Clarksville, Maryland); Graeme F. Woodworth (Baltimore, Maryland); Jeffrey A. Winkles (Frederick, Maryland); Aniket Wadajkar (Germantown, Maryland) |
| ABSTRACT | Metastatic triple negative breast cancer (TNBC) still carries a dismal prognosis with the current treatment paradigms. The effectiveness of drug treatment for many solid tumors such as TNBC is limited by tumor heterogeneity, lack of tumor specificity, off-target toxicities, and transient therapeutic action(s). Strategies that provide tumor-specific, sustained concentrations of drugs to the tumors and tumor receptor-specific binding, while reducing off-target effects are needed to ensure sufficient tumor cell uptake within the primary and metastatic tumor microenvironment. The decreased non-specific adhesivity, receptor-targeted nanoparticle formulations (“DART” nanoparticles) of the invention were assessed for clinical potential in directing biological agents to the cell surface receptor Fn14, which is expressed in many solid cancer types, including TNBC primary tumors and metastatic lesions. They are contemplated for use against solid tumors, particularly brain tumors such as glioblastoma and breast cancer, including metastatic breast cancer. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289424 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/5031 (20130101) A61K 31/337 (20130101) A61K 47/60 (20170801) A61K 47/6855 (20170801) A61K 47/6921 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2875 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045429 | Appel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric A. Appel (Cambridge, Massachusetts); Mark W. Tibbitt (Aarau, Switzerland); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Network materials which exhibit both shear thinning and self-healing properties are disclosed. The networks contain particles and gel-forming compounds. The networks are useful for a variety of biomedical uses, including drug delivery. |
| FILED | Monday, January 23, 2017 |
| APPL NO | 15/412935 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 9/5161 (20130101) Original (OR) Class A61K 47/30 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045441 | Baker et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Tracy Lee Baker (Verona, Wisconsin); Gordon Mitchell (Gainesville, Florida); Daryl Fields (Madison, Wisconsin) |
| ABSTRACT | Described is a method of inhibiting central apnea, central hypopnea or obstructive sleep apnea in a mammal. The method includes the step of administering to a mammal a central apnea inhibitory-effective, central hypopnea inhibitory-effective or obstructive sleep apnea inhibitory-effective amount of a composition comprising at least one retinoid or retinoid or retinoic acid receptor agonist. |
| FILED | Thursday, October 13, 2016 |
| APPL NO | 15/292699 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045456 | Li |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jian-Dong Li (Marietta, Georgia) |
| ABSTRACT | The present invention features, inter alia, pharmaceutical compositions and their use in the preparation of a medicament (e.g., a medicament for inflammation, such as an inflammatory lung disease) or in a therapeutic regimen. The compositions can include at least two active agents: a first agent that inhibits PDE4 (e.g., roflumilast) and a second active agent that inhibits the expression or activity of one or more PDE4B variants (e.g., PDE4B2). The compositions and methods will attenuate an unwanted up-regulation of a PDE4B (e.g., PDE4B2) and may thereby improve treatment with the first agent (e.g., roflumilast). For example, the second agent may improve the efficacy of the first agent, decrease the effective dose of the first agent, ameliorate the tolerance to the first agent that would otherwise develop (e.g., in patients with COPD exacerbation), reduce unwanted side effects caused by the first agent, or otherwise improve treatment regimes including a PDE4 inhibitor. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/559728 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 9/7023 (20130101) A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/44 (20130101) Original (OR) Class A61K 31/44 (20130101) A61K 31/423 (20130101) A61K 31/423 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/7088 (20130101) A61K 35/74 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/04053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045458 | Tang et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Weiping Tang (Middleton, Wisconsin); Ka Yang (Madison, Wisconsin); Hao Wu (Madison, Wisconsin) |
| ABSTRACT | Histone deacetylase (“HDAC”)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans. |
| FILED | Monday, July 22, 2019 |
| APPL NO | 16/517943 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4439 (20130101) Original (OR) Class Heterocyclic Compounds C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045462 | Braga et al. |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Maria F. Braga (Bethesda, Maryland); Vassiliki Aroniadou-Anderjaska (Bethesda, Maryland) |
| ABSTRACT | Described are methods of treating or reducing the toxic effects of exposure to a nerve agent, comprising administering to a subject in need thereof (i) an AMPA/GluR5(GluK1) kainate receptor antagonist (such as LY293558) and (ii) an NMD A receptor antagonist (such as an antimuscarinic compound, such as caramiphen), as well as methods of treating, reducing the risks of, or preventing a neurological condition such as epilepsy, seizures, post-traumatic stress disorder, status epilepticus, depression, or anxiety, comprising administering to a subject in need thereof (i) an AMPA/GluR5(GluK1) kainate receptor antagonist (such as LY293558) and (ii) an NMDA receptor antagonist (such as an antimuscarinic compound, such as caramiphen). The methods may further comprise administering a positive allosteric modulator of synaptic GABAA receptors, such as a benzodiazepine, such as midazolam, to the subject. The methods are suitable for use in children and adults. Related compositions and uses also are described. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 16/309898 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 31/41 (20130101) A61K 31/216 (20130101) A61K 31/4725 (20130101) Original (OR) Class A61K 31/5517 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045465 | Bhide et al. |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida); General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Pradeep G. Bhide (Peabody, Massachusetts); Jinmin Zhu (Allston, Massachusetts); Thomas J. Spencer (Carlisle, Massachusetts); Joseph Biederman (Brookline, Massachusetts) |
| ABSTRACT | Disclosed herein is a method of reducing or preventing the development of aversion to a CNS stimulant in a subject comprising, administering a therapeutic amount of the neurological stimulant and administering an antagonist of the kappa opioid receptor, to thereby reduce or prevent the development of aversion to the CNS stimulant in the subject. Also disclosed is a method of reducing or preventing the development of addiction to a CNS stimulant in a subject, comprising, administering the CNS stimulant and administering a mu opioid receptor antagonist to thereby reduce or prevent the development of addiction to the CNS stimulant in the subject. Also disclosed are pharmaceutical compositions comprising a central nervous system stimulant and an opioid receptor antagonist. Examples of central nervous system stimulants (such as methylphenidate) and opioid receptor antagonists (such as naltrexone) are provided. |
| FILED | Monday, June 24, 2013 |
| APPL NO | 13/924815 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/135 (20130101) A61K 31/135 (20130101) A61K 31/485 (20130101) Original (OR) Class A61K 31/485 (20130101) A61K 31/4458 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045473 | Smiraglia et al. |
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| APPLICANT(S) | Health Research, Inc. (Buffalo, New York); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Dominic Smiraglia (Buffalo, New York); Haley Affronti (Esopus, New York); Robert Casero (White Hall, Maryland) |
| ABSTRACT | Provided are compositions and methods for treating prostate conditions. The methods involve administering to an individual in need thereof a composition that contains i) an inhibitor of methionine salvage pathway in prostate of the individual and ii) a polyamine analogue. The methods are for use in individuals who have been diagnosed with, or are suspected of having or at risk for developing androgen sensitive prostate cancer (AS-CaP), or Castration recurrent CaP (CR-CaP), or benign prostate hyperplasia (BPH). The disclosure includes use of inhibitors of methylthioadenosine phosphorylase (MTAP), and a polyamine analog that upregulates polyamine catabolism by increasing spermidine/spermine N1-acetyl transferase (SAT1) activity, such as methyl-thio-DADMe-Immucillin (MTDIA), and 1),N(11)-bisethylnorspermine (BENSpm), respectively. Pharmaceutical formulations that contain a combination of the inhibitor of the methionine salvage pathway and a polyamine analogue are included, as are kits that contain such agents. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/575043 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/131 (20130101) A61K 31/132 (20130101) A61K 31/132 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045497 | Schneider et al. |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Dina Schneider (Potomac, Maryland); Rimas J. Orentas (Seattle, Washington); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing CD38 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/698186 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 16/2896 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045506 | Pamer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Eric Pamer (Montclair, New Jersey); Jedd D. Wolchok (New York, New York); Krista Dubin (New York, New York) |
| ABSTRACT | The present invention relates to methods and compositions for identifying subjects treated with or considered for treatment with checkpoint blockade therapeutic agents that are at higher or lower risk for developing checkpoint therapy associated colitis, by analyzing the intestinal microbiome of those subjects. It is based, at least in part, on the discovery that the abundance of certain intestinal microbiota of the phyla Bacteroidetes, including the bacteria in the families Bacteroidaceae, Rikenellaceae, and Barnesisllaceae, and/or an increase or decrease in microbial genetic pathways involved in polyamine transport and/or B vitamin biosynthesis (e.g., (riboflavin (B2), pantothenate (B5) and thiamine (B1)) are associated with the likelihood of developing checkpoint therapy associated colitis. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 15/984613 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 5/00 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0043 (20130101) A61K 9/0053 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2800/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045519 | Surviladze et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Zurab Surviladze (Albuquerque, New Mexico); Michelle A. Ozbun (Albuquerque, New Mexico); Andrew Cowan (Albuquerque, New Mexico) |
| ABSTRACT | An arginine-rich polypeptide composition includes an arginine-rich polypeptide and a pharmaceutically acceptable carrier. Generally, the arginine-rich polypeptide has at least nine arginine residues that represent at least 10% of the amino acid residues in the polypeptide. The arginine-rich polypeptide may be used in a method of inhibiting a human papilloma virus (HPV) from binding to a cell, a method of inhibiting intracellular processing of human papilloma virus (HPV) by a cell, or a method of treating a subject having, or at risk of having, a human papilloma virus (HPV) infection. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 16/482009 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0034 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/162 (20130101) A61K 47/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045525 | Iavarone et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Antonio Iavarone (New York, New York); Anna Lasorella (New York, New York) |
| ABSTRACT | The present disclosure provides, in one embodiment, a method of treating or preventing an ID2 protein-related disease in a patient at risk of developing or having such a disease by administering to the patient a composition in an amount and for a time sufficient to increase degradation of HIFα in a cell affected by the ID2 protein-related disease in the patent and/or to decrease half-life of HIFα in the cell affected by the ID2 protein-related disease in the patient, as compared to an untreated cell affected by the ID2 protein-related disease. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025668 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) A61K 38/45 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2510/00 (20130101) Enzymes C12Y 114/11002 (20130101) C12Y 207/12001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045545 | Pahan |
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| FUNDED BY |
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| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Kalipada Pahan (Skokie, Illinois) |
| ABSTRACT | A novel approach to discover new drugs against MS and other autoimmune diseases is disclosed. The p40 family of cytokines has four members which include interleukin-12 (IL-12), the p40 monomer (p40), the p40 homodimer (p402), and the IL-23. To facilitate the studies on p402 and p40, neutralizing monoclonal antibodies (mAb) against mouse p402 and p40 were generated for the first time. MS and other autoimmune disease drug therapies including recombinant p40 and/or monoclonal antibody against p402 (mAb-p402 a3-1d) are disclosed. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/130787 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/208 (20130101) A61K 39/3955 (20130101) Original (OR) Class Peptides C07K 16/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045548 | El-Sayed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Mostafa A. El-Sayed (Atlanta, Georgia); Moustafa R. K. Ali (Atlanta, Georgia) |
| ABSTRACT | A method of inhibiting migration of a cancer cell of a tumor in a subject comprising the steps of: (a) contacting the tumor with a gold nanomaterial; and (b) irradiating the tumor with an irradiation source. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/029193 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 33/242 (20190101) A61K 41/0052 (20130101) Original (OR) Class A61K 47/62 (20170801) A61K 47/64 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0613 (20130101) A61N 2005/067 (20130101) A61N 2005/0658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045556 | Buchman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Steven R. Buchman (Ann Arbor, Michigan); Mark Cohen (Ann Arbor, Michigan); Alexis Donneys (Ann Arbor, Michigan); Noah Nelson (Ann Arbor, Michigan); Laird Forrest (Lawrence, Kansas); Ti Zhang (Lawrence, Kansas); Qiuhong Yang (Lawrence, Kansas) |
| ABSTRACT | The present invention relates to novel therapeutic nanoparticles. In particular, the present invention is directed to nanoparticles associated (e.g., complexed, conjugated, encapsulated, absorbed, adsorbed, admixed) with angiogenesis-activating-agents, methods of synthesizing the same, devices or compositions comprising such nanoparticles, as well as systems and methods utilizing the nanoparticles (e.g., in therapeutic settings for enhancing and/or activating angiogenesis at targeted tissue region). |
| FILED | Friday, December 16, 2016 |
| APPL NO | 16/063061 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) A61K 31/16 (20130101) A61K 47/61 (20170801) A61K 47/6939 (20170801) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 2300/412 (20130101) A61L 2300/624 (20130101) A61L 2300/626 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) A61P 19/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045558 | Sandberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS EYE and EAR INFIRMARY (Boston, Massachusetts); UCL BUSINESS LTD. (London, United Kingdom); The Govt. of the USA, as represented by the Secy., Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); UCL Business Ltd. (London, United Kingdom); The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Michael A. Sandberg (Reading, Massachusetts); Basil Pawlyk (Hampton Falls, New Hampshire); Alan Finlay Wright (Edinburgh, United Kingdom); Xinhua Shu (Glasgow, United Kingdom); Tiansen Li (Clarksburg, Maryland); Robin Ali (London, United Kingdom) |
| ABSTRACT | Methods for treating a human subject who has X-linked Retinitis Pigmentosa (XLRP) or another clinically-defined ophthalmological condition due to a loss-of-function mutation in the gene encoding the retinitis pigmentosa GTPase regulator (RPGR) protein, the method comprising administering to the subject a nucleic acid comprising an adeno-associated viral vector comprising an abbreviated human RPGR cDNA. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436521 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/005 (20130101) Original (OR) Class Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045585 | Lee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Chang Hun Lee (New York, New York) |
| ABSTRACT | Provided herein is a 3D printing system and related compositions, and method of using such, that can produce a polymeric microfiber having embedded microspheres encapsulating an active agent with micron precision and high spatial and temporal resolution. One aspect of the present disclosure provides a method of forming a biocompatible scaffold. Another aspect provides a method of forming a polymeric fiber having a microencapsulated agent distributed in the polymeric fiber. Another aspect provides a composition including a polymeric microfiber produced by 3D printing. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/564101 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/44 (20130101) Original (OR) Class A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3608 (20130101) A61L 27/3834 (20130101) A61L 27/3847 (20130101) A61L 2300/414 (20130101) A61L 2300/602 (20130101) A61L 2300/622 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) A61L 2430/38 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/04 (20130101) B29K 2995/006 (20130101) B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045597 | Madhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Carnegie Mellon University (Pittsburgh, Pennsylvania); Mississippi State University (Starkville, Mississippi) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Carnegie Mellon University (Pittsburgh, Pennsylvania); Mississippi State University (Starkville, Mississippi) |
| INVENTOR(S) | Shalv Madhani (Pittsburgh, Pennsylvania); Brian Joseph Frankowski (Imperial, Pennsylvania); William J. Federspiel (Pittsburgh, Pennsylvania); Gregory Burgreen (Starkville, Mississippi); James F. Antaki (Allison Park, Pennsylvania) |
| ABSTRACT | An extracorporeal system for lung assist includes a housing which includes a blood flow inlet in fluid connection with a pressurizing stator compartment, a fiber bundle compartment in fluid connection with the pressurizing stator compartment via a flow channel within the housing, and a blood flow outlet in fluid connection with the fiber bundle compartment. An impeller is rotatably positioned within the pressurizing compartment. The system further includes a fiber bundle within the fiber bundle compartment. A plurality of hollow gas permeable fibers of the fiber bundle extend generally perpendicular to the direction of bulk flow of blood through the fiber bundle compartment from the flow channel to the blood flow outlet. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/738406 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1625 (20140204) A61M 1/1698 (20130101) A61M 1/3666 (20130101) A61M 1/3667 (20140204) Original (OR) Class A61M 60/82 (20210101) A61M 60/113 (20210101) A61M 60/205 (20210101) A61M 60/419 (20210101) A61M 60/818 (20210101) A61M 60/824 (20210101) A61M 2205/7536 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045620 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Gregory W. Hall (Belmont, Massachusetts); Ian J. Gillerman (Somerville, Massachusetts); Sina Mohsenian (Billerica, Massachusetts); Aubrey Ortiz (Boston, Massachusetts); Christopher Miles (Acton, Massachusetts); Wolfgang Scholz (Beverly, Massachusetts); Adam J. Young (Dedham, Massachusetts); Benjamin Apollonio (Lunenburg, Massachusetts) |
| ABSTRACT | Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875687 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/12 (20130101) Original (OR) Class A61M 16/024 (20170801) A61M 2202/0275 (20130101) A61M 2205/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045639 | Horvath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| INVENTOR(S) | David J. Horvath (Cleveland, Ohio); Leonard A R. Golding (Cleveland, Ohio); Barry D. Kuban (Cleveland, Ohio); Kiyotaka Fukamachi (Cleveland, Ohio) |
| ABSTRACT | A ventricular assist device includes a housing including a pumping chamber. A stator assembly is supported in the housing. The stator assembly includes a core having a length measured along a pump axis. A rotating assembly is rotatable relative to the stator assembly about the pump axis. The rotating assembly includes an impeller positioned in the pumping chamber and a rotor magnet. The rotating assembly is movable axially along the pump axis relative to the pump housing and the stator assembly. The rotating assembly includes a rotor magnet configured and arranged such that the magnetic attraction of the rotor magnet to the core urges the rotating assembly to move axially relative to the stator assembly such that a flow regulating portion of the rotating assembly engages with a corresponding portion of the housing to block flow through the pumping chamber when the pump is at rest. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/772154 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/50 (20210101) A61M 60/148 (20210101) Original (OR) Class A61M 60/205 (20210101) A61M 60/422 (20210101) A61M 60/833 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045807 | Meldrum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Deirdre Meldrum (Phoenix, Arizona); Laimonas Kelbauskas (Gilbert, Arizona); Yanqing Tian (Tempe, Arizona); Honor Glenn (Mesa, Arizona); Clifford Anderson (Tempe, Arizona); Kristen Lee (Mesa, Arizona); Ganquan Song (Mesa, Arizona); Liqiang Zhang (Chandler, Arizona); Jeff Houkal (Los Angeles, California); Fengyu Su (Tempe, Arizona); Benjamin Ueberroth (Scottsdale, Arizona); Jacob Messner (Scottsdale, Arizona); Hong Wang (Scottsdale, Arizona); Kimberly Bussey (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Deirdre Meldrum (Phoenix, Arizona); Laimonas Kelbauskas (Gilbert, Arizona); Yanqing Tian (Tempe, Arizona); Honor Glenn (Mesa, Arizona); Clifford Anderson (Tempe, Arizona); Kristen Lee (Mesa, Arizona); Ganquan Song (Mesa, Arizona); Liqiang Zhang (Chandler, Arizona); Jeff Houkal (Los Angeles, California); Fengyu Su (Tempe, Arizona); Benjamin Ueberroth (Scottsdale, Arizona); Jacob Messner (Scottsdale, Arizona); Hong Wang (Scottsdale, Arizona); Kimberly Bussey (Scottsdale, Arizona) |
| ABSTRACT | An integrated technological platform enabling real-time quantitative multiparameter metabolic profiling, utilizing either or both of extra and intracellular optical sensors, individually or simultaneously. A scalable embedded micropocket array structure, generally fabricated on fused silica substrates, facilitates the integration of multiple, spatially separated extracellular sensors for multiparameter analysis in a container formed with the use of an activation mechanism forming part of a device configured to hold the container during the measurements. The creation of hermetically sealed microchambers is carried out with a pneumatically and/or mechanically and/or electromechanically driven device that is “floating” within the holding device and that is optionally equipped with a vacuum/suction mechanism to hold a component of the container at its surface. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 16/479729 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50851 (20130101) Original (OR) Class B01L 3/50853 (20130101) B01L 2200/0668 (20130101) B01L 2300/046 (20130101) B01L 2300/0636 (20130101) B01L 2300/0822 (20130101) B01L 2400/0475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1484 (20130101) G01N 2015/1006 (20130101) Optical Elements, Systems, or Apparatus G02B 21/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046647 | Shapiro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | David J. Shapiro (Urbana, Illinois); Paul J. Hergenrother (Champaign, Illinois); Matthew W. Boudreau (Urbana, Illinois) |
| ABSTRACT | A set of small molecules ERα biomodulators that kill therapy-resistant ERα positive breast, ovarian, and endometrial cancer cells. These small molecules have increased therapeutic potential because of an increased ability to kill therapy-resistant breast cancer cells compared to BHPI and other conventional therapies (endocrine therapies, tamoxifen and fulvestrant/ICI). The new compounds do not only inhibit proliferation of the cancer cells but actually kills them, which prevents reactivation of tumors years later. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801839 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046692 | Pasternak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Gavril Pasternak (New York, New York); Susruta Majumdar (Stamford, Connecticut); Rashad Karimov (Berkeley, California); Andras Varadi (New York, New York) |
| ABSTRACT | Described herein are compounds of Formulae (I′)-(II′), compounds of Formulae (I)-(II) and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful for modulating opioid receptor activity. The provided compounds may have both agonistic and antagonistic effect on one or more opioid receptors. Methods of using the compounds for treating or managing pain are also described. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/570308 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/438 (20130101) A61K 31/438 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/04 (20180101) A61P 25/18 (20180101) A61P 29/00 (20180101) Heterocyclic Compounds C07D 471/14 (20130101) Original (OR) Class C07D 471/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046694 | Comita-Prevoir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Entasis Therapeutics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Entasis Therapeutics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Janelle Comita-Prevoir (Northborough, Massachusetts); Thomas Francois Durand-Reville (Belmont, Massachusetts); Satenig Guler (Waltham, Massachusetts); Jan Romero (Arlington, Massachusetts); Mark Sylvester (Waltham, Massachusetts); Ruben Tommasi (Stow, Massachusetts); Camilo Velez-Vega (Waltham, Massachusetts); Xiaoyun Wu (Westborough, Massachusetts); Jing Zhang (Sudbury, Massachusetts) |
| ABSTRACT | Provided herein are antibacterial compounds represented by Formula I, or a pharmaceutically acceptable salt thereof, wherein X, Y, R4, R5, and R6 are as defined herein. Also provided are pharmaceutical compositions comprising the compounds of Formula I. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 16/611065 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 471/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046703 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Shaomeng Wang (Superior Township, Michigan); Angelo Aguilar (Ann Arbor, Michigan); Yangbing Li (Ann Arbor, Michigan); Jiuling Yang (Ypsilanti, Michigan); Donna McEachern (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides compounds represented by Formula I: wherein R1a, R1b, R2a, R2b, R3a, R3b, R4, A, L, X, Y, and Z are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to degradation of MDM2 protein. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594344 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046709 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Shaomeng Wang (Superior Township, Michigan); Jiantao Hu (Ann Arbor, Michigan); Fuming Xu (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides fused 1,4-diazepines represented by Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein A, E, R1, R2, R3, R4, R5, and Ar are as defined as set forth in the specification. The present disclosure is also directed to the use of compounds having Formula (I) to treat diseases, conditions, or disorders responsive to inhibition of BET bromodomain proteins such as cancer. |
| FILED | Friday, February 02, 2018 |
| APPL NO | 16/481501 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) C07D 495/14 (20130101) C07D 498/04 (20130101) C07D 498/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046715 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| ASSIGNEE(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| INVENTOR(S) | Guangdi Wang (New Orleans, Louisiana); Shilong Zheng (New Orleans, Louisiana); Jiawang Liu (New Orleans, Louisiana); Qiu Zhong (New Orleans, Louisiana); Shanchun Guo (New Orleans, Louisiana) |
| ABSTRACT | The present disclosure relates to boronic derivatives of hydroxamate compounds, methods for making the same, methods for use as a monotherapy or in combination with one or more other therapeutic agents, for treatment of proliferative diseases such as cancer. The present disclosure also teaches the utilization of said boronic derivatives of hydroxamates as epigenetic therapy medications with enhanced bioavailability, lower-toxicity, and longer-lasting efficacy. |
| FILED | Monday, November 27, 2017 |
| APPL NO | 16/463622 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046716 | Burns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania) |
| INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Bin Liu (Plainsboro, New Jersey); Jiangchao Yao (Princeton, New Jersey); Denis Daigle (Street, Maryland); Steven A. Boyd (Chester Springs, Pennsylvania) |
| ABSTRACT | Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514904 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 31/546 (20130101) A61K 31/546 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046721 | Dmochowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ivan J. Dmochowski (Philadelphia, Pennsylvania); Julianne C. Griepenburg (Philadelphia, Pennsylvania); Teresa L. Rapp (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides ruthenium-based photolinker compounds, caged molecules comprising the ruthenium-based photolinker compounds, and methods of use. In certain aspects, the compositions disclosed herein comprise an active domain conjugated to a ruthenium-based photolinker, such that irradiation of the photolinker exposes the active domain. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 15/501070 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) B01J 2531/821 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0053 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/32 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2310/3233 (20130101) C12N 2310/3517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6823 (20130101) C12Q 1/6825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046729 | Suto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama); UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Vandana Gupta (Birmingham, Alabama); Bini Mathew (Hoover, Alabama); Joanne Murphy-Ullrich (Birmingham, Alabama) |
| ABSTRACT | The present disclosure is concerned with dipeptide analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, methods for immunotherapy, and methods of treating fibrotic conditions using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/172261 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/05 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Peptides C07K 5/0606 (20130101) C07K 5/06008 (20130101) C07K 5/06034 (20130101) C07K 5/06052 (20130101) C07K 5/06069 (20130101) C07K 5/06078 (20130101) C07K 5/06086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046730 | Nowick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James S. Nowick (Irvine, California); Hyun Jun Yang (San Francisco, California) |
| ABSTRACT | Antimicrobial molecules, their synthesis and use as antimicrobial treatments are described. The antimicrobial compounds are teixobactin analogues. Methods of synthesizing antimicrobial teixobactin analogues are also provided. Antibiotic therapeutics comprising antimicrobial teixobactin analogues are provided, along with methods of and formulations for treating microbial infections using such antimicrobial teixobactin analogues. Prodrugs formed using esterified forms of antimicrobial teixobactin analogues may also be provided. |
| FILED | Monday, April 17, 2017 |
| APPL NO | 16/091907 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/12 (20130101) A61K 38/15 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 7/56 (20130101) C07K 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046733 | Das Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Tapas Das Gupta (River Forest, Illinois); Ananda Chakrabarty (Villa Park, Illinois) |
| ABSTRACT | The present invention relates to compositions comprising CpG rich DNA from Pseudomonas aeruginosa. The compositions optionally comprise a cupredoxin. The present invention includes specific CpG DNAs from Pseudomonas aeruginosa that are useful for treating cancer and other conditions in patients. These compositions are optionally in a pharmaceutically acceptable carrier and also optionally comprise a cupredoxin. The present invention further relates to methods to express proteins near cancer cells. These methods may be used to express therapeutic or diagnostic proteins near cancer cells in a patient suffering from cancer or other conditions, and can also be used for diagnosing cancer in a patient. This method uses the gene for azurin from P. aeruginosa as an expression system for azurin or heterologous proteins in P. aeruginosa or heterologous cells. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 15/837066 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/21 (20130101) C07K 14/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046739 | Walensky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Newton, Massachusetts); Michelle L. Stewart (Cambridge, Massachusetts); Lauren Barclay (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are polypeptides containing stabilized BH4 domains of BCL-2 family proteins that are capable of binding and/or inactivating and/or modulating BAX protein, and/or its close homologues BAK and BOK, and/or other physiological BH4 targets. Also provided are compositions containing these polypeptides and methods of treating cytotoxic diseases that include administering to a subject one of the polypeptides. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119974 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/1761 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) Peptides C07K 14/4747 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 2333/47 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046740 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Carol S. Lim (Salt Lake City, Utah); Phong Lu (Salt Lake City, Utah) |
| ABSTRACT | Disclosed are peptides comprising a p53 peptide and a BH3-only protein. In some aspects, wherein the BH3-only protein is BAD, BID, BIM, NOXA. Disclosed are nucleic acid sequences comprising a sequence capable of encoding a p53 peptide operably linked to a nucleic acid sequence capable of encoding a BH3-only protein. Disclosed are nucleic acid sequences comprising a sequence capable of encoding one or more of the peptides disclosed herein. Disclosed are vectors comprising a nucleic acid sequence, wherein the nucleic acid sequence is capable of encoding one or more of the peptides disclosed herein. Also disclosed are methods of using the disclosed peptides, nucleic acid sequences, and vectors. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414683 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4746 (20130101) C07K 14/4747 (20130101) Original (OR) Class C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046750 | Spencer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | H. Trent Spencer (Marietta, Georgia); Christopher B. Doering (Atlanta, Georgia); Philip M. Zakas (Atlanta, Georgia); Eric Gaucher (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to recombinant or chimeric FVIII proteins, variants, and vectors encoding the proteins containing one or more ancestral mutations. In certain embodiments, one or more protein domains comprise amino acid sequences that are derived from ancestrally reconstructed amino acid sequences. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising the proteins or vectors and related methods of inducing blood clotting. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 16/874121 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046755 | Sierks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | (Scottsdale, Arizona) |
| INVENTOR(S) | Michael Sierks (Ft. McDowell, Arizona); Huilai Tian (Tempe, Arizona) |
| ABSTRACT | The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/672034 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/005 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/30 (20130101) C07K 2317/62 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/47 (20130101) G01N 2333/4703 (20130101) G01N 2800/28 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101) G01N 2800/7047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046765 | Edge |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Albert Edge (Brookline, Massachusetts) |
| ABSTRACT | This invention relates to methods for promoting reinnervation of auditory hair cells, specifically, by inhibiting Repulsive Guidance Molecule a (RGMa), a repulsive axonal guidance molecule that is expressed in the cochlea, or its receptor, neogenin. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448669 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 35/30 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/22 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046766 | Riddell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Stanley R. Riddell (Sammamish, Washington); Lingfeng Liu (Seattle, Washington) |
| ABSTRACT | The present disclosure relates to tagged chimeric effector molecules and receptor molecules thereof for genetically engineering a host cell, wherein the recombinant host cell can be identified, isolated, sorted, induced to proliferate, tracked or eliminated. For example, a T cell may be recombinantly modified for use in adoptive immunotherapy. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/664706 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/545 (20130101) A61K 38/1774 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 2035/124 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2878 (20130101) C07K 2317/64 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) C07K 2319/22 (20130101) C07K 2319/33 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0637 (20130101) C12N 5/0638 (20130101) C12N 2501/2302 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046782 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| INVENTOR(S) | Zihai Li (Mount Pleasant, South Carolina) |
| ABSTRACT | Isolated or recombinant monoclonal antibodies that bind to GARP are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. Further provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of an anti-platelet agent and a T cell therapy. |
| FILED | Thursday, March 30, 2017 |
| APPL NO | 16/089498 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0019 (20130101) A61K 31/675 (20130101) A61K 31/7076 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/34 (20130101) Original (OR) Class C07K 16/2827 (20130101) C07K 16/2866 (20130101) C07K 16/3015 (20130101) C07K 16/3046 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046854 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/740008 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) C09D 7/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046926 | Allbritton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Nancy Allbritton (Chapel Hill, North Carolina); Christopher Sims (Chapel Hill, North Carolina); Yuli Wang (Cary, North Carolina); Pavak Kirit Shah (Carrboro, North Carolina) |
| ABSTRACT | An apparatus for collecting or culturing cells or cell colonies includes: a common substrate formed from a flexible resilient polymeric material and having a plurality of wells formed therein; and a plurality of rigid cell carriers releasably connected to said common substrate, with said carriers arranged in the form of an array, and with each of the carriers resiliently received in one of the wells. A method of collecting or culturing cells or cell colonies with such an apparatus is carried out by depositing a liquid media carrying cells on the apparatus so that said cells settle on or adhere to said the carriers; and then (c) releasing at least one selected carrier having said cells thereon by gradual application of release energy to each carrier from the cavity in which it is received (e.g., by pushing with a probe). |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 15/945294 |
| ART UNIT | 1799 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00452 (20130101) B01J 2219/00743 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Original (OR) Class C12M 23/20 (20130101) C12M 23/22 (20130101) C12M 25/04 (20130101) C12M 25/16 (20130101) C12M 47/02 (20130101) C12M 47/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046933 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Tongxiang Lin (San Diego, California); Sheng Ding (Orinda, California) |
| ABSTRACT | The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (>200 fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, non-viral methods for reprogramming human somatic cells. |
| FILED | Friday, January 19, 2018 |
| APPL NO | 15/875928 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/065 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/28 (20130101) C12N 2506/094 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046934 | Kawaoka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Satoshi Fukuyama (Kanagawa, Japan); Shinji Watanabe (Tokyo, Japan) |
| ABSTRACT | The disclosure provides for an isolated recombinant influenza virus having at least one of: a PA gene segment encoding PA with a residue at position 443 that is not arginine, a PB1 gene segment encoding PB1 with a residue at position 737 that is not lysine, a PB2 gene segment encoding PB2 with a residue at position 25 that is not valine or a residue at position 712 that is not glutamic acid, a NS gene segment encoding a NS1 with a residue at position 167 that is not proline, a HA gene segment encoding a HA with a residue at position 380 that is not threonine, or any combination thereof, and methods of making and using the virus. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 15/966092 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) A61K 2039/525 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16131 (20130101) C12N 2760/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046948 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); John Paul Guilinger (Ridgway, Colorado); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One current drawback of TALEs is their tendency to bind and cleave off-target sequence, which hampers their clinical application and renders applications requiring high-fidelity binding unfeasible. This disclosure provides engineered TALE domains and TALEs comprising such engineered domains, e.g., TALE nucleases (TALENs), TALE transcriptional activators, TALE transcriptional repressors, and TALE epigenetic modification enzymes, with improved specificity and methods for generating and using such TALEs. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266937 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046954 | Bradner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | James Bradner (Weston, Massachusetts); Justin Roberts (Cambridge, Massachusetts); Behnam Nabet (Boston, Massachusetts); Georg Winter (Vienna, Austria); Andrew J. Phillips (Arlington, Massachusetts); Timothy Heffernan (Sugar Land, Texas); Dennis Buckley (Jamaica Plain, Massachusetts) |
| ABSTRACT | This invention is in the area of compositions and methods for regulating chimeric antigen receptor immune effector cell, for example T-cell (CAR-T), therapy to modulate associated adverse inflammatory responses, for example, cytokine release syndrome and tumor lysis syndrome, using targeted protein degradation. |
| FILED | Tuesday, February 06, 2018 |
| APPL NO | 15/889963 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/551 (20130101) A61K 31/575 (20130101) A61K 31/4525 (20130101) A61K 31/4545 (20130101) A61K 31/4985 (20130101) A61K 31/5513 (20130101) A61K 35/17 (20130101) A61K 48/00 (20130101) A61K 2035/122 (20130101) Peptides C07K 14/47 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/00 (20130101) C07K 16/2863 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046957 | Mueller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Christian Mueller (Concord, Massachusetts); Neil Aronin (Newtonville, Massachusetts); Edith L. Pfister (Boxborough, Massachusetts) |
| ABSTRACT | Aspects of the disclosure relate to compositions and methods useful for treating Huntington's disease. In some embodiments, the disclosure provides interfering nucleic acids (e.g., artificial miRNAs) targeting the huntingtin gene (HTT) and methods of treating Huntington's disease using the same. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/573412 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/3519 (20130101) C12N 2330/51 (20130101) C12N 2750/14121 (20130101) C12N 2750/14141 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046959 | Schiller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LA (Las Vegas, Nevada) |
| ASSIGNEE(S) | The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas (Las Vegas, Nevada) |
| INVENTOR(S) | Martin R. Schiller (Henderson, Nevada); Christy L. Strong (Henderson, Nevada) |
| ABSTRACT | Disclosed herein, are compositions and methods for the treatment of human immunodeficiency virus infection. The compositions comprise engineered transcription activator like effector nucleases (TALENs) comprising a TALE DNA binding domain flanked by two spacer sequences, and a Fokl nuclease catalytic domain. Also, described herein, are methods of using TALENs to cleave nucleic acids; and methods of administering the TALENs to subjects at risk for or having an HIV infection. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/562962 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/03 (20130101) A61K 45/06 (20130101) A61K 48/0066 (20130101) A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 2319/09 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/1132 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 301/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046962 | Close et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 490 BioTech, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Close (Knoxville, Tennessee); Steven Ripp (Knoxville, Tennessee); Gary Sayler (Blaine, Tennessee); Michael Conway (Medford, Massachusetts) |
| ABSTRACT | Cells, including stem cells, comprising an autobioluminescent phenotype, wherein the cells emit a luminescent signal in the absence of an exogenous luminescent stimulator, are provided. The luminescent signal may be constitutive, inducible, repressible, or tissue-specific. The cells express a synthetically engineered bacterial luciferase (lux) cassette, i.e., the luxCDABEfrp gene cassette. The cells may comprise luxA, luxB, luxC, luxD, luxE, and flavin reductase. The cells may each express a combined expression level of luxC, luxD, luxE, and flavin reductase that is from ten to forty times greater than a combined expression level of luxA and luxB. Further, methods of making and using the cells comprising an autobioluminescent phenotype are disclosed herein. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/888639 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 15/64 (20130101) Original (OR) Class C12N 15/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) Enzymes C12Y 105/0103 (20130101) C12Y 114/14003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046996 | Chee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (San Diego, California); David A. Routenberg (San Diego, California) |
| ABSTRACT | The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180356 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047000 | Green |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexander Green (Scottsdale, Arizona) |
| ABSTRACT | Provided herein are imaging probes and systems and methods employing such imaging probes for real-time, label-free, multiplexed imaging of RNAs in living cells. More particularly, aptamer-based sensors (“aptasensors”) and molecular fuses comprising multiple aptasensors are genetically encoded imaging probes comprising RNA-target binding sequence and an intramolecular reconfiguration sequence. The probe is configured such that binding of a RNA target by the RNA-target binding sequence triggers the intramolecular reconfiguration sequence to reconfigure such that an optically detectable output is generated by the probe. |
| FILED | Friday, December 15, 2017 |
| APPL NO | 16/468846 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class C12Q 2525/205 (20130101) C12Q 2525/301 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047001 | Zong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Chenghang Zong (Houston, Texas); Michael Gundry (Houston, Texas); Kuanwei Sheng (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure encompass methods of amplifying nucleic acid from one or more cells. In particular embodiments, the nucleic acid is amplified as amplicons in a linear manner. Specific embodiments include the removal or effective destruction of nonlinearly produced amplicons. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/407032 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 1/6844 (20130101) Original (OR) Class C12Q 1/6846 (20130101) C12Q 1/6846 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2531/119 (20130101) C12Q 2531/119 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047003 | Rotem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Assaf Rotem (Cambridge, Massachusetts); Oren Ram (Chestnut Hill, Massachusetts); Bradley E. Bernstein (Cambridge, Massachusetts); David A. Weitz (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally relates to microfluidics and/or epigenetic sequencing. In one set of embodiments, cells contained within a plurality of microfluidic droplets are lysed and the DNA (e.g., from nucleosomes) within the droplets are labeled, e.g., with adapters containing an identification sequence. The adapters may also contain other sequences, e.g., restriction sites, primer sites, etc., to assist with later analysis. After labeling with adapters, the DNA from the different cells may be combined and analyzed, e.g., to determine epigenetic information about the cells. For example, the DNA may be separated on the basis of certain modifications (e.g., methylation), and the DNA from the separated nucleosomes may be sequenced using techniques such as chromatin immunoprecipitation (“ChIP”). In some cases, the DNA sequences may also be aligned with genomes, e.g., to determine which portions of the genome were epigenetically modified, e.g., via methylation. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670929 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0071 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/301 (20130101) C12Q 2525/131 (20130101) C12Q 2525/161 (20130101) C12Q 2563/159 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047006 | Salk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/908611 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047009 | Niculescu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Alexander B. Niculescu (Indianapolis, Indiana) |
| ABSTRACT | Biomarkers and methods for screening expression levels of the biomarkers for predicting and tracking suicidality, as well as for monitoring response to a treatment for suicidal risk and for determining suicidal risk as a side-effect of an antidepressant are disclosed. |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/091706 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/9466 (20130101) G01N 2800/52 (20130101) G01N 2800/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047693 | Schaefer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A system provides feedback to a user to guide the user to point a part of the body at a target of interest. An angle sensor senses the angle in which the part of the user's body is pointing, such as the head or the hand. The system computes the angle to a target and compares to the angle in which the part of the user's body is pointing and the feedback indicates to the user how to point more closely to the direction of the target. Additional sensors allow the system to update the angle to the target as the position of the user changes. A walking sensor is disclosed to accurately measure the position of the user. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123028 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3415 (20130101) Original (OR) Class G01C 21/3476 (20130101) G01C 21/3629 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/012 (20130101) G06F 3/013 (20130101) G06F 3/016 (20130101) G06F 3/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047860 | Liebler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Daniel C. Liebler (Brentwood, Tennessee); Lisa J. Zimmerman (Franklin, Tennessee); Robbert J. C. Slebos (Baltimore, Maryland) |
| ABSTRACT | Provided are methods for measuring the amount of a target protein in a heterogeneous multicellular biospecimen having two or more cell types. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/773719 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047861 | Mrksich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Milan Mrksich (Hinsdale, Illinois); Eric J. Berns (Park Ridge, Illinois); Maria D. Cebezas (Evanston, Illinois) |
| ABSTRACT | The disclosure provides a cell-based, label-free assay compatible with high-throughput screening (HTS) that can report quantitatively on enzyme activities by measuring mass changes of substrates with MALDI-mass spectrometry. |
| FILED | Monday, August 08, 2016 |
| APPL NO | 15/750030 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) C12Q 1/26 (20130101) C12Q 1/37 (20130101) C12Q 1/42 (20130101) C12Q 1/44 (20130101) C12Q 1/46 (20130101) C12Q 1/48 (20130101) C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6851 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047868 | Zimring |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bloodworks (Seattle, Washington) |
| ASSIGNEE(S) | Bloodworks (Seattle, Washington) |
| INVENTOR(S) | James Charles Zimring (Seattle, Washington) |
| ABSTRACT | Compositions and methods for determining post-transfusion survival or toxicity of red blood cells and the suitability of red blood cell units for transfusion by measuring the levels of one or more markers in a red blood cell sample are provided. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 16/750984 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2800/7066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047869 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana); Christina Ramires Ferreira (West Lafayette, Indiana); Allison Lisa Dill (Indianapolis, Indiana); Demian R. Ifa (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a tissue sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/891793 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0036 (20130101) H01J 49/142 (20130101) H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047906 | Erington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| ASSIGNEE(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| INVENTOR(S) | Kent Erington (Austin, Texas); Daniel J. Bodoh (Austin, Texas); Keith Serrels (Fremont, California); Theodore Lundquist (Milpitas, California) |
| ABSTRACT | Method to extract timing diagrams from synchronized single- or two-photon pulsed LADA by spatially positioning the incident laser beam on circuit feature of interest, temporally scanning the arrival time of the laser pulse with respect to the tester clock or the loop length trigger signal, then recording the magnitude and sign of the resulting fail rate signature per laser pulse arrival time. A Single-Photon Laser-Assisted Device Alteration apparatus applies picosecond laser pulses of wavelength having photon energy equal to or greater than the silicon band-gap. A Two-Photon Laser-Assisted Device Alteration apparatus applies femtosecond laser pulses of wavelength having photon energy equal to or greater than half the silicon band-gap at the area of interest. The laser pulses are synchronized with test vectors so that pass/fail ratios can be altered using either the single-photon or the two-photon absorption effect. A sequence of synthetic images with error data illustrates timing sensitive locations. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259903 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/311 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048388 | Herbst |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Innovations Holdings, L.L.C. (Edgewater, New Jersey) |
| ASSIGNEE(S) | Innovations Holdings, L.L.C. (Edgewater, New Jersey) |
| INVENTOR(S) | Ewa Herbst (Edgewater, New Jersey) |
| ABSTRACT | The invention relates to methods and devices to define and control the design of a configurable chip module, instrument or systems, for example, for measurement, control and communication systems or any portion thereof. The module may include one or more chip elements. This can be achieved using, for example, a Graphical User Interface (GUI), that transforms selections made by the user to a hardware and/or software configuration for the system in a process transparent to the user. This enables implementation of a plurality of devices and larger subsystems on a chip or a chip module without specific semiconductor design knowledge from the user. This transformation process is thus accomplished transparently to the user, who operates the GUI to define the measurement or action which needs to be performed, thereby resulting in an automatic combination of hardware and/or software elements available to create a specific configuration. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113783 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/32 (20130101) A61N 1/36014 (20130101) A61N 1/37247 (20130101) Electric Digital Data Processing G06F 3/0481 (20130101) G06F 3/0484 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11045394 | Schulz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SIERRA NEVADA CORPORATION (Sparks, Nevada) |
| ASSIGNEE(S) | Sierra Nevada Corporation (Sparks, Nevada) |
| INVENTOR(S) | Karl Schulz (Sparks, Nevada); Richard Campbell (Sparks, Nevada); Emily Huang (Sparks, Nevada); Sarah Koh (Sparks, Nevada); Kurnhee Ma (Sparks, Nevada) |
| ABSTRACT | Mobile systems and methods are adapted to control and document prehospital patient care reports and communication of patient status to a receiving medical treatment facility. The systems and methods relate to systems and methods for managing, recording, and administering drugs such as narcotics in an ambulatory and/or emergency environment. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297021 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 50/22 (20160201) A61B 50/31 (20160201) Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 7/04 (20130101) A61J 7/0069 (20130101) Original (OR) Class A61J 7/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045462 | Braga et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Maria F. Braga (Bethesda, Maryland); Vassiliki Aroniadou-Anderjaska (Bethesda, Maryland) |
| ABSTRACT | Described are methods of treating or reducing the toxic effects of exposure to a nerve agent, comprising administering to a subject in need thereof (i) an AMPA/GluR5(GluK1) kainate receptor antagonist (such as LY293558) and (ii) an NMD A receptor antagonist (such as an antimuscarinic compound, such as caramiphen), as well as methods of treating, reducing the risks of, or preventing a neurological condition such as epilepsy, seizures, post-traumatic stress disorder, status epilepticus, depression, or anxiety, comprising administering to a subject in need thereof (i) an AMPA/GluR5(GluK1) kainate receptor antagonist (such as LY293558) and (ii) an NMDA receptor antagonist (such as an antimuscarinic compound, such as caramiphen). The methods may further comprise administering a positive allosteric modulator of synaptic GABAA receptors, such as a benzodiazepine, such as midazolam, to the subject. The methods are suitable for use in children and adults. Related compositions and uses also are described. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 16/309898 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 31/41 (20130101) A61K 31/216 (20130101) A61K 31/4725 (20130101) Original (OR) Class A61K 31/5517 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045493 | Gianneschi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nathan C. Gianneschi (La Jolla, California); Yuran Huang (La Jolla, California); Yiwen Li (La Jolla, California) |
| ABSTRACT | Provided, inter alia, are synthetic melanin nanoparticles (MelNPs) useful for protecting keratinocytes from UV-damage and for treating melanin-defective diseases. |
| FILED | Tuesday, July 11, 2017 |
| APPL NO | 16/317003 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 31/787 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045555 | Zink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey I. Zink (Sherman Oaks, California); Bastian Ruehle (Los Angeles, California); Marcus A. Horwitz (Los Angeles, California); Daniel L. Clemens (Los Angeles, California); Bai-Yu Lee Clemens (Los Angeles, California) |
| ABSTRACT | In various embodiments nanoparticle drug delivery vehicles are provided that specifically deliver a cargo to a target pathogenic organism. In certain embodiments the drug delivery vehicle comprises a mesoporous silica nanoparticle comprising a plurality of pores and an outer surface through which the pores are disposed; a cargo disposed in the pores; one or more antigens attached to the surface of the nanoparticle; an antibody that specifically binds the antigens and are bound to the antigens, wherein the antibody inhibits diffusion of the cargo out of the pores and permit release of the cargo when the drug delivery vehicle is in the presence of the antigen or a pathogen displaying the antigen. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389715 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) A61K 39/12 (20130101) A61K 47/6803 (20170801) A61K 47/6835 (20170801) A61K 47/6839 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 2039/60 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/12 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045602 | Patel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
| INVENTOR(S) | Himanshu Patel (Rancho Santa Margarita, California); Edward R. Damiano (Acton, Massachusetts); Firas H. El-Khatib (Allston, Massachusetts); Michael J. Rosinko (Anaheim, California) |
| ABSTRACT | Systems and methods presented herein relate to a method of sharing therapy data of an ambulatory medical device with a computing system of a networked computing environment. The computing system may be identified using an authorized system list that includes an address of approved computing systems. Using an address of an approved computing system, a direct end-to-end data connection may be established via a wireless wide area network. A public key of the computing system may be received permitting the ambulatory medical device to encrypt data to be transmitted to the computing system. The ambulatory medical device can transmit the encrypted therapy data to the computing system over the direct end-to-end data connection. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062217 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045644 | Meng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); HUNTINGTON MEDICAL RESEARCH INSTITUTES (Pasadena, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); HUNTINGTON MEDICAL RESEARCH INSTITUTES (Pasadena, California) |
| INVENTOR(S) | Ellis Meng (Los Angeles, California); Victor Pikov (Los Angeles, California) |
| ABSTRACT | A new class of peripheral nerve interfaces that combines microfluidics with microelectronics. A peripheral nerve interface that allows intraneural targeting through the combined use and sequential application of lysing agents and neurotrophic factors. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/752110 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/6877 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0556 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045676 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Linda S Lee (West Lafayette, Indiana); Jenny E Zenobio (Arlington, Massachusetts) |
| ABSTRACT | The present application relates to a novel method for reductive degradation of perfluoroalkyl-containing compounds, such as perfluoroalkyl sulfonates, by activated carbon (AC) supported zero valent iron-nickel nanoparticles (nNi0Fe0). |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/056646 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/34 (20130101) Original (OR) Class A62D 3/37 (20130101) A62D 2101/22 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/755 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) C02F 1/705 (20130101) C02F 2101/36 (20130101) C02F 2103/06 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045783 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Michael Stanley Wleklinski (Indianapolis, Indiana); David Logsdon (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a portion of which react with each other within the liquid spray discharge to form a reaction product. The system also includes a collector positioned to receive the liquid spray discharge including the unreacted molecules and the reaction product. The system also includes a recirculation loop connected from the collector to the pneumatic sprayer in order to allow the unreacted molecules and the reaction product to be recycled through the pneumatic sprayer, thereby allowing a plurality of the unreacted molecules to react with each other as the unreacted molecules cycle again through the system. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 15/673658 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 5/0069 (20130101) B01D 19/0031 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/002 (20130101) B01J 14/00 (20130101) B01J 19/26 (20130101) B01J 19/087 (20130101) B01J 19/2465 (20130101) Original (OR) Class B01J 2219/00087 (20130101) B01J 2219/00099 (20130101) B01J 2219/0803 (20130101) B01J 2219/0884 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/03 (20130101) B05B 5/025 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046415 | Pankonien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of Americas as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Alexander Pankonien (Fairborn, Ohio); Nitin Bhagat (Fairborn, Ohio); Ryan Durscher (Loveland, Ohio) |
| ABSTRACT | Additive and subtractive manufacturing (e.g. 3D Printing) is used to form aeroelastic airfoils with control surface region(s) having conventional rib/spar structural topologies and a continuous skin (e.g smooth surface) formed over the entire outer surface of the airfoil. The control surface is moved with internal actuators resulting in a “morphing” airfoil as the skin stretches to follow the moving structure of the control surface region. The airfoil can include a plurality of different material moduli and geometric featuring to balance the appropriate control of stiffness with topological requirements. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 16/403726 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Aeroplanes; Helicopters B64C 3/24 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046579 | Giordano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Braden C. Giordano (Reston, Virginia); Pehr E. Pehrsson (Fairfax Station, Virginia); Kevin J. Johnson (Alexandria, Virginia); Daniel Ratchford (Alexandria, Virginia); Christopher Field (Arlington, Virginia); Junghoon Yeom (Okemos, Michigan) |
| ABSTRACT | Disclosed herein is a method of providing a structure having two electrodes connected by nanowires, exposing the structure to an analyte that can adsorb onto the nanowires, and passing an electrical current through the nanowires to heat the nanowires to desorb the analyte. Also disclosed herein is an apparatus having the above structure; a current source electrically connected to the electrodes, and a detector to detect the analyte. |
| FILED | Monday, December 09, 2019 |
| APPL NO | 16/707120 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Original (OR) Class B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/124 (20130101) G01N 27/127 (20130101) G01N 27/4146 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/06744 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/456 (20130101) H01L 29/0665 (20130101) H01L 29/0676 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046647 | Shapiro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | David J. Shapiro (Urbana, Illinois); Paul J. Hergenrother (Champaign, Illinois); Matthew W. Boudreau (Urbana, Illinois) |
| ABSTRACT | A set of small molecules ERα biomodulators that kill therapy-resistant ERα positive breast, ovarian, and endometrial cancer cells. These small molecules have increased therapeutic potential because of an increased ability to kill therapy-resistant breast cancer cells compared to BHPI and other conventional therapies (endocrine therapies, tamoxifen and fulvestrant/ICI). The new compounds do not only inhibit proliferation of the cancer cells but actually kills them, which prevents reactivation of tumors years later. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801839 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046652 | Jiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HAWAII BIOTECH, INC. (Honolulu, Hawaii) |
| ASSIGNEE(S) | HAWAII BIOTECH, INC. (Honolulu, Hawaii) |
| INVENTOR(S) | Guan-Sheng Jiao (Aiea, Hawaii); Alan T. Johnson (Kaneohe, Hawaii); Sean O'Malley (Honolulu, Hawaii); Seong Jin Kim (Honolulu, Hawaii) |
| ABSTRACT | Compounds of Formula I are provided: R1 is —OR5, m is an integer from 0 to 5, n is an integer from 0 to 2, each R2 is independently selected from hydrogen, halogen, and alkyl, R3 is selected from hydrogen, alkyl, cycloalkyl, aryl, hydroxyalkyl, alkoxyalkyl, aryloxyalkyl, aralkyloxyalkyl, aralkyl, alkylaminoalkyl, dialkylaminoalkyl, aralkylaminoalkyl, and heterocycloalkyl, R5 is an alkyl, each R4 is independently hydrogen or alkyl, and each of R2, R3, R4, and R5 is independently optionally substituted. Compounds of Formula I are included in pharmaceutical compositions for the treatment of a subject exposed to a botulinum toxin. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 16/911075 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046815 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Shannon Olga White (Hudson, Massachusetts); Nicholas Anthony Zafiropoulos (Wayland, Massachusetts); Jimmy Lee Clark (Newhall, California) |
| ABSTRACT | The present invention provides articles and methods related to insulation panels made from aerogels, and specifically polyimide based aerogels. Such insulation panels have a wide variety of applications, including specifically in aerospace applications. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/371184 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/04 (20130101) B32B 3/266 (20130101) B32B 5/10 (20130101) B32B 5/18 (20130101) B32B 5/32 (20130101) B32B 27/281 (20130101) B32B 2266/04 (20130101) B32B 2266/06 (20130101) B32B 2266/057 (20161101) B32B 2266/102 (20161101) B32B 2266/126 (20161101) B32B 2266/0214 (20130101) B32B 2266/0292 (20130101) B32B 2307/72 (20130101) B32B 2307/302 (20130101) B32B 2307/304 (20130101) B32B 2307/416 (20130101) B32B 2307/546 (20130101) B32B 2605/18 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/10 (20130101) Original (OR) Class C08G 73/1067 (20130101) C08G 2110/0091 (20210101) C08G 2330/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 7/06 (20130101) C08K 7/06 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) C08L 79/08 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/233 (20150115) Y10T 428/249953 (20150401) Y10T 428/249986 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046823 | Kengla |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| INVENTOR(S) | Carlos Kengla (Winston-Salem, North Carolina) |
| ABSTRACT | Provided herein are improved compositions and methods of making and using the same, the composition comprising a polymer and a ceramic present at a ratio of from 3:1 to 1:3 of polymer:ceramic by weight, wherein the composition comprises or is a composite of the polymer and the ceramic having improved printability and/or having an improved elastic modulus and/or improved stress at failure (e.g., as compared to a blend of the polymer and the ceramic). |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 16/322219 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/56 (20130101) A61L 2430/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/12 (20130101) C08J 3/205 (20130101) Original (OR) Class C08J 9/008 (20130101) C08J 2367/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/32 (20130101) C08K 2003/325 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046854 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/740008 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) C09D 7/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046873 | Wilker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan James Wilker (Lafayette, Indiana); Michael A. North (Lafayette, Indiana); Chelsey A. Del Grosso (West Lafayette, Indiana) |
| ABSTRACT | Embodiments of this invention relate to methods of adhering in an aqueous environment. More specifically, embodiments of this invention relate to use of a copolymer mimics of mussel adhesive proteins as a high-strength adhesive in aqueous environments. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 16/327382 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/04 (20130101) C09J 125/08 (20130101) Original (OR) Class C09J 2301/414 (20200801) C09J 2400/163 (20130101) C09J 2400/303 (20130101) C09J 2425/00 (20130101) C09J 2427/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046948 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); John Paul Guilinger (Ridgway, Colorado); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One current drawback of TALEs is their tendency to bind and cleave off-target sequence, which hampers their clinical application and renders applications requiring high-fidelity binding unfeasible. This disclosure provides engineered TALE domains and TALEs comprising such engineered domains, e.g., TALE nucleases (TALENs), TALE transcriptional activators, TALE transcriptional repressors, and TALE epigenetic modification enzymes, with improved specificity and methods for generating and using such TALEs. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266937 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047053 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NuTech Ventures, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Troy Anderson (Omaha, Nebraska); Sidy Ndao (Lincoln, Nebraska); Craig Zuhlke (Lincoln, Nebraska); Dennis Alexander (Lincoln, Nebraska); George Gogos (Lincoln, Nebraska) |
| ABSTRACT | A system embodiment includes, but is not limited to, a solid structure configure to contact each of a material in a liquid phase and a material in a vapor phase, the solid structure including a plurality of microstructures protruding at angles relative to a horizontal plane; and a layer of nanoparticles positioned on the plurality of microstructures, the layer of nanoparticles having a composition that is at least one of a same material as the plurality of microstructures and an oxide of the same material as the plurality of microstructures, the plurality of microstructures defining one or more valleys, each of the one or more valleys positioned between the layer of nanoparticles of adjacent microstructures of the plurality of microstructures, the one or more valleys configured to govern at least one of a size and a shape of a bubble of the material in the vapor phase. |
| FILED | Tuesday, January 13, 2015 |
| APPL NO | 14/595452 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/02 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
11047078 — Aligned discontinuous fiber preforms, composites and systems and processes of manufacture
| US 11047078 | Tierney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Tierney (Wilmington, Delaware); Alex Vanarelli (Westfield, New Jersey); Dirk Heider (Newark, Delaware); Shridhar Yarlagadda (Newark, Delaware); John W. Gillespie, Jr. (Hockessin, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | John Tierney (Wilmington, Delaware); Alex Vanarelli (Westfield, New Jersey); Dirk Heider (Newark, Delaware); Shridhar Yarlagadda (Newark, Delaware); John W. Gillespie, Jr. (Hockessin, Delaware) |
| ABSTRACT | A process for aligning discontinuous fibers, and composite products and mats comprised of highly aligned discontinuous fibers, including products of the process. Aligned discontinuous fiber composite products include a matrix of fibers, each fiber having a longitudinal fiber axis, the composite comprising a free, uncut edge extending along an edge axis. The longitudinal fiber axis of a majority of the fibers in the composite product are aligned within a predetermined alignment tolerance of an alignment axis non-parallel to the edge axis. Aligned discontinuous fiber mats may have a first areal density of fibers in a first region of the composite located inward relative to the free, uncut edge, and a second area density at or adjacent to the free, uncut edge. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/843362 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/14 (20130101) B29C 70/50 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/12 (20130101) B32B 5/022 (20130101) B32B 5/26 (20130101) B32B 2250/20 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) C08J 2363/00 (20130101) C08J 2379/08 (20130101) C08J 2381/06 (20130101) C08J 2479/08 (20130101) C08J 2481/06 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/74 (20130101) Original (OR) Class D04H 1/4374 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2505/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047334 | Sperry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ACHATES POWER, INC. (San Diego, California) |
| ASSIGNEE(S) | Achates Power, Inc. (San Diego, California) |
| INVENTOR(S) | Robert G. Sperry (Columbus, Indiana); James R. Shaw (Columbus, Indiana) |
| ABSTRACT | An air intake system is provided that supplies charge air to multiple cylinders in an in-line configuration in an uniflow-scavenged, two-stroke opposed-piston engine. The engine is configured such that the intake ports of the cylinders are situated in one intake chamber within the engine block. The air intake chamber includes a feature to balance the mass of air that reaches the intake port of each cylinder in the engine. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/681430 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 25/08 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/4235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047666 | Blazek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin M. Blazek (Ridgecrest, California); Lee R. Hardt (Ridgecrest, California) |
| ABSTRACT | Embodiments employ venting features and damping components both inside and concentric to a fuzewell to improve munition fuze survivability. Damping components are selected based on their densities and stiffness properties. A shock damping liner with longitudinal grooves is affixed to an inner surface of the fuzewell and envelops the fuze. At least one shock damping collar constrains and attenuates shock experienced by the fuze. A shock damping ring is concentric about the outer surface of the fuzewell and attenuates shock between the outermost munition system layer (the casing) and the fuzewell. Longitudinal vents in the fuzewell wall and radial apertures oriented transverse to the longitudinal vents are used for off-gassing. The venting and component orientation combination provides increased damping, resulting in impedance mismatches across multiple interface surfaces in the munition, which reduces shock vibrational pressures and stresses transferred to the fuze. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/390883 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/207 (20130101) F42B 39/14 (20130101) F42B 39/20 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 19/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047687 | Feke |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Gilbert D. Feke (Windham, New Hampshire) |
| ABSTRACT | A fiber management assembly for a multi-axis fiber optic gyroscope (FOG) includes a mounting block. The mounting block includes an integrated optical circuit (IOC) mounting feature configured to permit mounting thereon an IOC. The mounting block further includes coil mounting features configured to permit mounting at least two optical fiber coils at the mounting block with the at least two fiber coils aligned in substantially different directions in three-dimensional space. The mounting block further includes an exterior surface having at least one substantially exterior, curved zone onto which connecting segments of respective optical fibers between the IOC and respective coils of the at least two optical fiber coils are routed and affixed. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 16/476719 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/722 (20130101) Original (OR) Class G01C 19/728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047873 | Calantoni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Calantoni (Diamondhead, Mississippi); Edward Braithwaite (Covington, Louisiana); Callum Gray (Ann Arbor, Michigan); Sean Griffin (Slidell, Louisiana) |
| ABSTRACT | Systems and methods are provided for making in-situ measurements of the sea bed 3 component fluid velocity field and sediment motion across a range of real ocean conditions using particle image velocimetry (PIV). A PIV system in accordance with an embodiment of the present disclosure can include a camera to capture images of the particles in motion, a laser to generate a laser sheet for illuminating the particles, and a synchronizer to act as an external trigger for the laser and the camera. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/428781 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) G01P 5/20 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 7/292 (20170101) G06T 2207/30181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047874 | Reich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Gregory W. Reich (Bellbrook, Ohio); Kaman Thapa Magar (Beavercreek, Ohio); Keith Slinker (Beavercreek, Ohio); Corey R. Kondash (Beavercreek, Ohio); Benjamin T. Dickinson (Destin, Florida); Jeffrey W. Baur (Liberty Township, Ohio); Alexander M. Pankonien (Fairborn, Ohio) |
| ABSTRACT | Systems and associated methods for utilizing an artificial hair sensor to gather fluid flow data sensed on a surface. The artificial hair sensors are disposed on a surface to acquire flow sensory data in approximately real-time and for a plurality of dynamic flow parameters on the surface. The sensory data is based on a quantity of the artificial hair sensors that can be configured in an array of sensors. A mapping module, such as a neural network, is operatively coupled to the artificial hair sensor array and receives the sensory data acquired by the artificial hair sensors and generates a time-varying signal, which is based on the quantity of dynamic parameters. A real-time representation of the time-varying signal is generated. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/162780 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/26 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/9038 (20190101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047898 | Lang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | David A. Lang (San Diego, California) |
| ABSTRACT | A system and associated method determines the characteristics of an electric network including distance to a fault through the use of a power divider and a measuring device that measures a quantity from which voltage magnitude can be determined. The measuring device may be a power detector. The power detector may include a power meter to measure voltage and/or a power sensor to measure amplitude. Then, the results from the power detector are used in conjunction with a Hilbert transform to estimate the phase associated with at least two voltage magnitudes when a combined signal is a minimum phase signal. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273668 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/28 (20130101) G01R 31/11 (20130101) G01R 31/086 (20130101) G01R 31/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047906 | Erington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| ASSIGNEE(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| INVENTOR(S) | Kent Erington (Austin, Texas); Daniel J. Bodoh (Austin, Texas); Keith Serrels (Fremont, California); Theodore Lundquist (Milpitas, California) |
| ABSTRACT | Method to extract timing diagrams from synchronized single- or two-photon pulsed LADA by spatially positioning the incident laser beam on circuit feature of interest, temporally scanning the arrival time of the laser pulse with respect to the tester clock or the loop length trigger signal, then recording the magnitude and sign of the resulting fail rate signature per laser pulse arrival time. A Single-Photon Laser-Assisted Device Alteration apparatus applies picosecond laser pulses of wavelength having photon energy equal to or greater than the silicon band-gap. A Two-Photon Laser-Assisted Device Alteration apparatus applies femtosecond laser pulses of wavelength having photon energy equal to or greater than half the silicon band-gap at the area of interest. The laser pulses are synchronized with test vectors so that pass/fail ratios can be altered using either the single-photon or the two-photon absorption effect. A sequence of synthetic images with error data illustrates timing sensitive locations. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259903 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/311 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047967 | Nixon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | James H. Nixon (Helotes, Texas); Brock A. Martin (Helotes, Texas); John J. Signorotti (Fair Oaks Ranch, Texas); Robert G. Fenske, Jr. (San Antonio, Texas) |
| ABSTRACT | A method of operating a vertical incidence sounder. The sounder transmits a random modulated sounder signal, and receives a return signal, comprising a directwave component and a reflected component. A first cross-ambiguity process between the transmitted signal and the return signal is used to time and frequency align the return signal with the transmitted signal. The direct wave signal is removed, thereby producing a processed return signal. A second cross-ambiguity process between the transmitted signal and the processed return signal is performed to determine a time offset, which is used to estimate an ionospheric height. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/033740 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/0218 (20130101) Original (OR) Class G01S 19/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047997 | Holland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Darren Holland (Springfield, Ohio); Robert Olesen (Fairborn, Ohio); Larry Burggraf (Washington Township, Ohio); Buckley O'Day (Dunn Loring, Virginia); James Bevins (Bellbrook, Ohio) |
| ABSTRACT | A radiation imaging system images a distributed source of radiation from an unknown direction by rotating a scatter mask around a central axis. The scatter mask has a pixelated outer surface of tangentially oriented, flat geometric surfaces that are spherically varying in radial dimension that corresponds to a discrete amount of attenuation. Rotation position of the scatter mask is tracked as a function of time. Radiation counts from gamma and/or neutron radiation are received from at least one radiation detector that is positioned at or near the central axis. A rotation-angle dependent detector response curve (DRC) is generated based on the received radiation counts. A reconstruction algorithm for distributed radiation source(s) and/or localized source(s) are applied based on the tracked rotation position and prior characterization of the detector response for a given scatter mask. A two-dimensional image with relative orientation and source distribution is generated from the measured DRC. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007063 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/4258 (20130101) Measurement of Nuclear or X-radiation G01T 1/2018 (20130101) G01T 3/06 (20130101) G01T 7/00 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048062 | Reid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Bryan M. Reid (Chelmsford, Massachusetts); Mark Silver (Bedford, Massachusetts); Robert Martinez (Providence, Rhode Island); Alan Decew (West Newton, Massachusetts); Adam Shabshelowitz (Cambridge, Massachusetts); Michael Chrisp (Burlington, Massachusetts) |
| ABSTRACT | An imaging system includes a metering structure and a plurality of foldable members disposed around a periphery of the metering structure. Each foldable member in the plurality of foldable members includes an arm comprising a strain deployable composite and a reflector disposed on the arm. The arm in a respective foldable member in the plurality of foldable members is configured to hold the respective foldable member toward the metering structure in a first state and to hold the respective foldable member away from the metering structure in a second state such that the reflector of the respective foldable member forms part of a sparse aperture in the second state. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293018 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/66 (20130101) B64G 1/222 (20130101) B64G 1/1021 (20130101) Optical Elements, Systems, or Apparatus G02B 7/183 (20130101) Original (OR) Class G02B 7/1827 (20130101) G02B 17/0808 (20130101) G02B 23/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048313 | Jana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Siddhartha Jana (Hillsboro, Oregon); Federico Ardanaz (Hillsboro, Oregon); Jonathan M. Eastep (Portland, Oregon); Yaxin Shui (San Diego, California); Keith Underwood (Powell, Tennessee) |
| ABSTRACT | Described herein are automated hierarchical feed-back driven control mechanisms and methods, including an apparatus comprising a first circuitry, a second circuitry, and a third circuitry. The first circuitry may be operable to receive a system operating characteristic guidance. The second circuitry may be operable to provide one or more manufacturing characteristics. The third circuitry may be operable to store one or more system operating characteristics based upon the system operating characteristic guidance and the one or more manufacturing characteristics. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369580 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3206 (20130101) Original (OR) Class G06F 1/3234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048852 | Fallon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cadence Design Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Cadence Design Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Elias Lee Fallon (Allison Park, Pennsylvania); Wangyang Zhang (Allison Park, Pennsylvania); Sheng Qian (Sunnyvale, California) |
| ABSTRACT | The present disclosure relates to a computer-implemented method for electronic circuit design. Embodiments may include receiving, using at least one processor, data corresponding to an electronic design schematic. Embodiments may further include analyzing the data to learn one or more device size parameters, a range of parameters, or a matching relationship of parameters based upon, at least in part, the electronic design schematic or the electronic design layout, wherein analyzing occurs without user action. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 16/523416 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) G06F 30/27 (20200101) G06F 30/337 (20200101) G06F 30/373 (20200101) G06F 30/398 (20200101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049001 | Alvarez-Icaza Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (Austin, Texas); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas) |
| ABSTRACT | The present invention provides a system comprising multiple core circuits. Each core circuit comprises multiple electronic axons for receiving event packets, multiple electronic neurons for generating event packets, and a fanout crossbar including multiple electronic synapse devices for interconnecting the neurons with the axons. The system further comprises a routing system for routing event packets between the core circuits. The routing system virtually connects each neuron with one or more programmable target axons for the neuron by routing each event packet generated by the neuron to the target axons. Each target axon for each neuron of each core circuit is an axon located on the same core circuit as, or a different core circuit than, the neuron. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/049539 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049410 | Talke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kurt A Talke (San Diego, California); Nicholas C Stroumtsos (San Diego, California); Dylan T. J. Drotman (San Diego, California) |
| ABSTRACT | A device includes a frame having a plurality of rails, each rail including a slider. A first rail support member is connected to a first end of the plurality of rails, and a second rail support member is connected to a second end of the plurality of rails. The second end is opposite the first end. A plurality of arms is connected to the sliders. Each arm includes a ball joint at one end connected to one of the sliders. Each arm includes another end, opposite the one end, connected to a platform via a hinge joint. The platform is configured to roll and pitch via changing positions of the sliders along the plurality of rails. |
| FILED | Wednesday, August 15, 2018 |
| APPL NO | 15/998802 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1623 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/12 (20130101) Original (OR) Class G09B 9/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049551 | Lenjani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Marzieh Lenjani (Charlottesville, Virginia); Patricia Gonzalez (Knoxville, Tennessee); Mircea R. Stan (Charlottesville, Virginia); Kevin Skadron (Charlottesville, Virginia) |
| ABSTRACT | A method of processing data in a memory can include accessing an array of memory cells located on a semiconductor memory die to provide a row of data including n bits, latching the n bits in one or more row buffer circuits adjacent to the array of memory cells on the semiconductor memory die to provide latched n bits operatively coupled to a column address selection circuit on the semiconductor memory die to provide a portion of the n latched bits as data output from the semiconductor memory die responsive to a memory read operation, and serially transferring the latched n bits in the row buffer circuit to an arithmetic logic unit (ALU) circuit located adjacent to the row buffer circuit on the semiconductor memory die. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 16/682151 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 7/57 (20130101) G06F 13/1668 (20130101) Static Stores G11C 11/4082 (20130101) G11C 11/4087 (20130101) G11C 11/4093 (20130101) Original (OR) Class G11C 11/4096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049985 | Choi |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kwong-Kit Choi (Brookeville, Maryland) |
| ABSTRACT | A photo detection device comprising a contact layer through which light enters; an absorbing region positioned such that light admitted through the contact layer passes into the absorbing region; at least one diffractive element operatively associated with the absorbing region operating to diffract light into the absorbing region; the configuration of the at least one diffractive element being determined by computer simulation to determine an optimal diffractive element (or elements) and absorbing region configuration for optimal quantum efficiency for at least one predetermined wavelength detection range, the at least one diffractive element operating to diffract light entering through the contact layer such that phases of diffracted waves from locations within the photo detection device or waves reflected by sidewalls and waves reflected by the at least one diffractive element form a constructive interference pattern inside the absorbing region. A method of designing a photodetector comprises using a computer simulation to determine an optimal configuration for at least one wavelength range occurring when waves reflected by the diffractive element form a constructive interference pattern inside the absorbing region. |
| FILED | Thursday, December 28, 2017 |
| APPL NO | 15/856632 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) G06F 30/23 (20200101) G06F 30/39 (20200101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) H01L 31/103 (20130101) H01L 31/0296 (20130101) H01L 31/0304 (20130101) H01L 31/0324 (20130101) H01L 31/1013 (20130101) H01L 31/1037 (20130101) H01L 31/02168 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/02966 (20130101) H01L 31/03046 (20130101) H01L 31/035218 (20130101) H01L 31/035236 (20130101) H01L 31/035281 (20130101) H01L 51/44 (20130101) H01L 51/0046 (20130101) H01L 51/426 (20130101) H01L 51/447 (20130101) H01L 51/4213 (20130101) H01L 2031/0344 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050031 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hong Koo Kim (Wexford, Pennsylvania); Daud Hasan Emon (Hillsboro, Oregon) |
| ABSTRACT | Various light emitting diode device embodiments that include emissive material elements, e.g., core-shell quantum dots, that are either (i) provided in nanoscale holes provided in an insulating layer positioned between an electron supply/transport layer and a hole supply/transport layer, or (ii) provided on a suspension layer positioned above and covering a nanoscale hole in such an insulating layer. Also, various methods of making such light emitting diode devices, including lithographic and non-lithographic methods. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 16/655389 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/3246 (20130101) H01L 51/0037 (20130101) H01L 51/0042 (20130101) H01L 51/50 (20130101) Original (OR) Class H01L 51/52 (20130101) H01L 51/56 (20130101) H01L 51/0096 (20130101) H01L 51/502 (20130101) H01L 51/5004 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050082 | Rodrigues et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Stanley J. Rodrigues (Dayton, Ohio); Padmakar D. Kichambare (Beavercreek, Ohio) |
| ABSTRACT | A colloidal ionic-liquid electrolyte for electrochemical devices is provided. The colloidal ionic-liquid electrolyte includes a room temperature ionic-liquid, a lithium salt, and a ceramic particle phase (powder) including a high dielectric material dispersed in the ionic-liquid electrolyte, wherein the colloidal ionic-liquid electrolyte exhibits enhanced ionic conductivity in the electrochemical device compared to the ionic conductivity of the pure room temperature ionic-liquid. The high dielectric material exhibits a first dielectric constant of about 200 or more, and a first mean particle size of about 2000 nm or less. The enhanced ionic conductivity is observed in the temperature range of about 75° C. to about −60° C. and is more pronounced at colder temperatures. In addition, the colloidal ionic-liquid electrolyte exhibits enhanced non-flammability, enhanced mechanical stability, enhanced thermal stability and suppressed flowability. |
| FILED | Wednesday, September 27, 2017 |
| APPL NO | 15/717050 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/00 (20130101) C01B 35/066 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/005 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0563 (20130101) Original (OR) Class H01M 10/0566 (20130101) H01M 10/0567 (20130101) H01M 10/0569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050085 | Rhodes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Christopher P. Rhodes (College Station, Texas); Matthew E. Mullings (College Station, Texas) |
| ABSTRACT | An electrolyte for an electrochemical storage device is disclosed. In one embodiment, the electrolyte includes a lithium salt from about 3% to about 20% by weight, a primary solvent from about 15% to about 25% by weight, wide-temperature co-solvents from about 14% to about 55% by weight, interface forming compounds from about 0.5% to about 2.0% by weight, and a flame retardant compound from about 6% to about 60% by weight. The electrolyte interacts with the positive and negative electrodes of the electrochemical storage device to provide both high performance and improved safety such that the electrolyte offers adequate ionic conductivity over the desired operating temperature range, a wide electrochemical stability window, high capacities for both the cathode and anode, low electrode-electrolyte interfacial resistance, and reduced flammability. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/182067 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/60 (20130101) H01G 11/62 (20130101) H01G 11/64 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/004 (20130101) H01M 2300/0037 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050093 | Eskra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
| ASSIGNEE(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
| INVENTOR(S) | Michael David Eskra (Saukville, Wisconsin); Paula Margaret Ralston (Frederick, Maryland); Richard Thomas Johnson (Howard, Colorado) |
| ABSTRACT | A bipolar lead acid battery with increased energy density is provided. The battery includes a number of lead acid wafer cell that each comprise a negative electrode having a negative electrode plate and a negative active material positioned on the negative electrode plate, as well as a positive electrode having a positive electrode plate and a positive active material positioned on the positive electrode plate. The positive electrode plate comprises a metal foil with a conductive film thereon, such as a titanium foil or substrate with a titanium silicide coating thereon. The lead acid wafer cell also includes a separator between the negative and positive electrodes, wherein the separator includes an electrolyte for transferring charge between the negative and positive electrodes. |
| FILED | Monday, June 25, 2018 |
| APPL NO | 16/016777 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/14 (20130101) H01M 4/624 (20130101) H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 10/10 (20130101) H01M 10/18 (20130101) Original (OR) Class H01M 50/172 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050121 | Eskra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
| ASSIGNEE(S) | Eskra Technical Products, Inc. (Saukville, Wisconsin) |
| INVENTOR(S) | Michael David Eskra (Saukville, Wisconsin); Paula Margaret Ralston (Frederick, Maryland) |
| ABSTRACT | A system and method for providing a ceramic-based separator onto an electrode is disclosed. A separator is formed on the electrode via a dry, solvent-free application of a ceramic-based separator to the electrode. An electrode is provided to an application area via a feed mechanism and a separator layer is then applied to the electrode that is comprised of a binder including at least one of a thermoplastic material and a thermoset material and an electrically non-conductive separator material, with the separator layer being applied to the electrode via a dry dispersion application. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062883 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 50/46 (20210101) Original (OR) Class H01M 50/403 (20210101) H01M 50/446 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050160 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Hualiang Zhang (Arlington, Massachusetts); Bowen Zheng (Dracut, Massachusetts) |
| ABSTRACT | An antenna device as described herein includes a first metal layer and a second metal layer. The second metal layer is spaced apart from the first metal layer. The first metal layer includes an opening through which to transmit RF (Radio Frequency) energy to the second metal layer. The second metal layer is operable to reflect the RF energy received through the opening back to a surface of the first metal layer. The first metal layer is operable to reflect the RF energy (received from the reflection off the second metal layer) in a direction past the second metal layer through a communication medium. The surface area of the first metal layer is sufficiently larger than a surface area of the second metal layer to reflect the RF energy past the second metal layer into the communication medium. This ensures that the antenna device operates in a reflective mode as opposed to a resonant mode, resulting in high gain. |
| FILED | Monday, April 16, 2018 |
| APPL NO | 15/953739 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/2039 (20130101) Antennas, i.e Radio Aerials H01Q 5/42 (20150115) H01Q 15/14 (20130101) H01Q 19/005 (20130101) Original (OR) Class H01Q 19/185 (20130101) H01Q 21/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050214 | Loh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | William Loh (Cambridge, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts); Siva Yegnanarayanan (Lexington, Massachusetts) |
| ABSTRACT | In an ultrastable laser, using a large mode-volume optical resonator, which suppresses the resonator's fast thermal fluctuations, together with the stimulated Brillouin scattering (SBS) optical nonlinearity presents a powerful combination that enables the ability to lase with an ultra-narrow linewidth of 20 Hz. The laser's long-term temperature drift is compensated by using the narrow Brillouin line to sense minute changes in the resonator's temperature (e.g., changes of 85 nK). The precision of this temperature measurement enables the stabilization of resonators against environmental perturbations. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 16/401750 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) Original (OR) Class H01S 3/1305 (20130101) H01S 3/1312 (20130101) H01S 3/1317 (20130101) H01S 3/2383 (20130101) H01S 3/09415 (20130101) H01S 3/10053 (20130101) H01S 3/10061 (20130101) H01S 3/094003 (20130101) H01S 3/094053 (20130101) H01S 3/094069 (20130101) H01S 3/094096 (20130101) H01S 5/0687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050284 | Thillaiyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | EAGLEPICHER TECHNOLOGIES, LLC (Joplin, Missouri) |
| ASSIGNEE(S) | EAGLEPICHER TECHNOLOGIES, LLC (Joplin, Missouri) |
| INVENTOR(S) | Ramanathan Thillaiyan (Joplin, Missouri); Wujun Fu (Joplin, Missouri); Mario Destephen (Joplin, Missouri); Gregory Lee Miller (Diamond, Missouri); Eivind Listerud (Osceola, Missouri); Eric Lloyd Quee (Seneca, Missouri) |
| ABSTRACT | An improved electrolyte including a fire-retardant additive suitable for application in wide temperature cell and/or battery operation with safer cell design, a battery including the electrolyte and a separator optionally containing a fire-retardant additive, improved electrical and thermal conductive electrodes are disclosed. The presence of the fire-retardant additive reduces flammability of the electrolyte and improved the overall safety of the battery. |
| FILED | Thursday, June 04, 2015 |
| APPL NO | 14/730590 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/405 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) H01M 10/446 (20130101) H01M 10/0567 (20130101) H01M 10/0569 (20130101) H01M 10/4235 (20130101) H01M 2300/0025 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050447 | Ganje et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Stephen A. Ganje (Frisco, Texas); Nathan Larsen (Allen, Texas); Yongtao Guo (Plano, Texas); Jeffrey L. Box (Farmersville, Texas) |
| ABSTRACT | A system may include a receiver, an input digitized data buffer, and a processor. The input digitized data buffer may be configured to accumulate samples of a time domain signal, s(t), from the receiver. The processor may be configured to: remove a confirmed peak from a frequency domain signal, S(f), to produce a corrected frequency domain signal, S′(f); perform an inverse fast Fourier transform to transform the corrected frequency domain signal, S′(f), to a corrected time domain signal, s′(t); perform an inverse window operation on the corrected time domain signal, s′(t), to recover original signal magnitudes; and output digitized data of the corrected time domain signal, s′(t), for signal processing. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780491 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/10 (20130101) Original (OR) Class H04B 1/082 (20130101) Secret Communication; Jamming of Communication H04K 3/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050770 | Nanda et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Soumendra Nanda (Billerica, Massachusetts); Rebecca Cathey (Apison, Tennessee); Lawrence A. Clough, Jr. (Reston, Virginia); Adrian E. Conway (Weston, Massachusetts); Fang Liu (Cupertino, California) |
| ABSTRACT | A network defense system can include a sensor alert ingestion framework adapted to monitor network activity and alert detected or suspected anomalies. A network analyzer may be coupled to the sensor alert ingestion framework to analyze the anomalies. A course of action (CoA) simulator may be coupled to the network analyzer adapted to generate a list of decision including courses of action to address the anomalies. There may be a training and feedback unit coupled to the CoA simulator to train the system to improve responses in addressing future anomalies. |
| FILED | Thursday, August 02, 2018 |
| APPL NO | 16/053279 |
| ART UNIT | 2493 — Cryptography and Security |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/046 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/0263 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050876 | Balasubramaniyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Vijay Balasubramaniyan (Atlanta, Georgia); Mustaque Ahamad (Atlanta, Georgia); Patrick Gerard Traynor (Decatur, Georgia); Michael Thomas Hunter (Atlanta, Georgia); Aamir Poonawalla (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Monday, December 30, 2019 |
| APPL NO | 16/730666 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0829 (20130101) H04L 65/1076 (20130101) Telephonic Communication H04M 1/68 (20130101) H04M 3/2281 (20130101) Original (OR) Class H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) H04W 12/63 (20210101) H04W 12/65 (20210101) H04W 24/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050963 | Tyrrell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Brian M. Tyrrell (Brookline, New Hampshire); Christy Fernandez Cull (Sunnyvale, California); Andrew K. Bolstad (Arlington, Massachusetts) |
| ABSTRACT | Conventional methods for imaging transient targets are constrained by a trade-off between resolution and frame rate, and transient targets moving faster than the detector frame typically result in image blurring. Imagers using digital-pixel focal plane arrays (“DFPAs”) have on-chip global pixel operation capability for extracting a single transient-feature (i.e., single-frequency discrimination) in a snapshot that depends on the number of counters implemented per pixel. However, these DFPA systems are not capable of multi-target and multi-frequency discrimination. Imagers described herein achieve multi-target transient signature discrimination orders of magnitude faster than the readout frame rate using in-pixel electronic shuttering with a known time-encoded modulation. Three-dimensional (x,y,t) data cube reconstruction is performed using compressive sensing algorithms. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/816354 |
| ART UNIT | 2697 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/335 (20130101) H04N 5/37455 (20130101) Original (OR) Class H04N 7/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051230 | Huntsman et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Steven C. Huntsman (Alexandria, Virginia); Brian T. Decleene (North Reading, Massachusetts); Jeong-O Jeong (Ashburn, Virginia) |
| ABSTRACT | A method and system for a Wireless Resilient Routing Reconfiguration linear program or protocol (WR3LP). The WR3LP provides a routing protection scheme that is (i) congestion-free or reduced congestion under a wide range of failure scenarios in point-to-multipoint networks, (ii) efficient in terms of router processing overhead and memory requirement in wireless and point-to-multipoint networks, (iii) flexible in accommodating diverse performance requirements in wireless and point-to-multipoint networks (e.g., different traffic protection levels), and (iv) robust to traffic variations and topology failures in wireless and point-to-multipoint networks. |
| FILED | Wednesday, August 22, 2018 |
| APPL NO | 16/463100 |
| ART UNIT | 2466 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/16 (20130101) H04L 45/22 (20130101) Wireless Communication Networks H04W 40/30 (20130101) Original (OR) Class H04W 40/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D923342 | Dugas et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Anabela Dugas (Rochester, Massachusetts); Scotlund McIntosh (Framingham, Massachusetts) |
| ABSTRACT | |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 29/729361 |
| ART UNIT | 2918 — Design |
| CURRENT CPC | Textile or paper yard goods; sheet material D5/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11045427 | John et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
| ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | Vijay John (Destrehan, Louisiana); Gary McPherson (Mandeville, Louisiana) |
| ABSTRACT | The present invention discloses the morphology of hollow, double-shelled submicrometer particles generated through a rapid aerosol-based process. The inner shell is an essentially hydrophobic carbon layer of nanoscale dimension (5-20 nm), and the outer shell is a hydrophilic silica layer of approximately 5-40 nm, with the shell thickness being a function of the particle size. The particles are synthesized by exploiting concepts of salt bridging to lock in a surfactant (CTAB) and carbon precursors together with iron species in the interior of a droplet. This deliberate negation of surfactant templating allows a silica shell to form extremely rapidly, sealing in the organic species in the particle interior. Subsequent pyrolysis results in a buildup of internal pressure, forcing carbonaceous species against the silica wall to form an inner shell of carbon. The incorporation of magnetic iron oxide into the shells opens up applications in external stimuli-responsive nanomaterials. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 15/695387 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/501 (20130101) A61K 9/5089 (20130101) Original (OR) Class A61K 9/5094 (20130101) A61K 9/5192 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) B01J 13/22 (20130101) B01J 21/18 (20130101) B01J 21/063 (20130101) B01J 23/745 (20130101) B01J 35/002 (20130101) B01J 35/004 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/026 (20130101) B01J 35/0033 (20130101) B01J 35/1057 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 37/08 (20130101) B01J 37/0072 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/34 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/62 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) C09B 61/00 (20130101) C09B 67/0008 (20130101) C09B 67/0097 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) C09C 1/30 (20130101) C09C 1/407 (20130101) C09C 1/3607 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2031 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/587 (20130101) H01M 4/8605 (20130101) H01M 4/8657 (20130101) H01M 4/9041 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045554 | Negrete et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Oscar Negrete (Livermore, California); C. Jeffrey Brinker (Albuquerque, New Mexico); Torri Rinker (San Francisco, California); Annette Estelle LaBauve (Hayward, California) |
| ABSTRACT | The present invention relates to lipid-coated particles for treating viral infections, including viral encephalitis infections. In particular, an antiviral compound can be disposed within the lipid-coated particle, thereby providing an antiviral carrier. Methods of making and using such carriers are described herein. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443316 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/4965 (20130101) A61K 47/543 (20170801) A61K 47/6913 (20170801) A61K 47/6915 (20170801) Original (OR) Class A61K 47/6917 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045772 | Belfort et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Georges Belfort (Slingerlands, New York); Joseph Grimaldi (Clifton Park, New York); Joseph Imbrogno (Massapequa, New York); James Kilduff (Saratoga Springs, New York); John Joseph Keating (Troy, New York) |
| ABSTRACT | The present invention relates to synthetic membranes and use of these synthetic membranes for isolation of volatile organic compounds and purification of water. The synthetic membrane includes a hydrophobic polymer layer located on a polymeric membrane support layer. The invention includes a method of isolating volatile organic compounds with the synthetic membrane by contacting a volatile organic mixture with the hydrophobic polymer layer of the synthetic membrane and removing volatile organic compounds from the polymeric membrane support layer of the synthetic membrane by a process of pervaporation. The invention also includes a method of purifying water with the synthetic membrane by contacting an ionic solution with the hydrophobic polymer layer of the synthetic membrane and removing water from the polymeric membrane support layer of the synthetic membrane by a process of reverse osmosis. The invention also relates to methods of isolating non-polar gases by gas fractionation. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/180322 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 61/02 (20130101) B01D 61/025 (20130101) B01D 61/362 (20130101) B01D 67/0006 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/28 (20130101) B01D 71/40 (20130101) B01D 71/52 (20130101) B01D 71/68 (20130101) B01D 71/78 (20130101) B01D 2257/708 (20130101) B01D 2323/08 (20130101) B01D 2323/34 (20130101) B01D 2323/38 (20130101) B01D 2323/345 (20130101) B01D 2323/385 (20130101) B01D 2325/02 (20130101) B01D 2325/26 (20130101) B01D 2325/38 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2103/08 (20130101) Acyclic or Carbocyclic Compounds C07C 29/86 (20130101) Technologies for Adaptation to Climate Change Y02A 50/235 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045851 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Vineet V. Joshi (Richland, Washington); Scott A. Whalen (West Richland, Washington); Curt A. Lavender (Richland, Washington); Glenn J. Grant (Benton City, Washington); MD. Reza-E-Rabby (Richland, Washington); Aashish Rohatgi (Richland, Washington); Jens T. Darsell (West Richland, Washington) |
| ABSTRACT | A process for forming extruded products using a device having a scroll face configured to apply a rotational shearing force and an axial extrusion force to the same preselected location on material wherein a combination of the rotational shearing force and the axial extrusion force upon the same location cause a portion of the material to plasticize, flow and recombine in desired configurations. This process provides for a significant number of advantages and industrial applications, including but not limited to extruding tubes used for vehicle components with 50 to 100 percent greater ductility and energy absorption over conventional extrusion technologies, while dramatically reducing manufacturing costs. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028173 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/002 (20130101) B21C 23/08 (20130101) B21C 23/142 (20130101) B21C 23/215 (20130101) B21C 23/218 (20130101) B21C 25/02 (20130101) Original (OR) Class B21C 27/00 (20130101) B21C 29/003 (20130101) B21C 33/00 (20130101) B21C 37/155 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2003/208 (20130101) B22F 2301/058 (20130101) Alloys C22C 1/0408 (20130101) C22C 1/0416 (20130101) C22C 1/0425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046048 | Briggs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Timothy Briggs (Brentwood, California); Brian T. Werner (Livermore, California); Joseph Carlson (Castro Valley, California) |
| ABSTRACT | A laminate comprising a first ply, a second ply, and a plurality of interfacial modifiers arranged between opposing faces of the first ply and the second ply. A chemical composition of an interfacial modifier of the plurality of interfacial modifiers can be selected based on a resulting bond strength between the interfacial modifier of the plurality of interfacial modifiers and at least one of the first ply or the second ply. The plurality of interfacial modifiers can be arranged in a pattern to selectively modify toughness of a portion of the laminate based on the bond strength of the interfacial modifier of the plurality of interfacial modifiers. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065061 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/05 (20190101) Original (OR) Class B32B 27/36 (20130101) B32B 27/306 (20130101) B32B 2307/558 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046463 | Dallmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Nicholas Dallmann (Los Alamos, New Mexico); James Wren (Los Alamos, New Mexico); Michael Proicou (Los Alamos, New Mexico); Hannah Mohr (Los Alamos, New Mexico); Jerry Delapp (Los Alamos, New Mexico); Kimberly Katko (Los Alamos, New Mexico); John Martinez (Los Alamos, New Mexico); Donathan Ortega (Los Alamos, New Mexico); Daniel Seitz (Los Alamos, New Mexico); Paul Stein (Los Alamos, New Mexico); Justin Tripp (Los Alamos, New Mexico); Adam Warniment (Los Alamos, New Mexico); Robert Wheat, Jr. (Los Alamos, New Mexico) |
| ABSTRACT | A compact SFS may can be deployed in small space vehicles. The SFS may have a small size, weight, and low power requirements. The hardware, software, catalogs, and calibration algorithm of the SFS provide highly accurate attitude information that can be used for pointing. For instance, accurate attitude determination may be provided that supports pointing of a deployable high gain helical antenna. A full “lost in space” attitude solution, accurate to about an arcminute, may be accomplished in under a minute. The SFS may be fully reprogrammable on orbit, allowing continued algorithm development and deployment after launch. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043345 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/244 (20190501) B64G 1/361 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7867 (20130101) G01S 5/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046623 | Dagle et al. |
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| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Vanessa M. Dagle (Richland, Washington); Robert A. Dagle (Richland, Washington) |
| ABSTRACT | Simple and economical conversion of aqueous ethanol feed streams into butenes by a single step method using transition metal oxides on a silica supports under preselected processing conditions. By directly producing a C4-rich olefin mixture from an ethanol containing stream various advantages are presented including, but not limited to, significant cost reduction in capital expenses and operational expenses. |
| FILED | Monday, May 11, 2020 |
| APPL NO | 16/871285 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/20 (20130101) Original (OR) Class C07C 11/08 (20130101) C07C 2521/06 (20130101) C07C 2523/50 (20130101) C07C 2529/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046642 | Karp et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Eric M. Karp (Denver, Colorado); Gregg Tyler Beckham (Golden, Colorado); Derek Richard Vardon (Lakewood, Colorado); Todd R. Eaton (Denver, Colorado) |
| ABSTRACT | An aspect of the present disclosure is a method that includes a first reacting a molecule from at least one of a carboxylic acid, an ester of a carboxylic acid, and/or an anhydride with ammonia to form a nitrile, where the first reacting is catalyzed using an acid catalyst. In some embodiments of the present disclosure, the molecule may include at least one of acetic acid, lactic acid, and/or 3-hydroxyproprionic acid (3-HPA). In some embodiments of the present disclosure, the molecule may include at least one of methyl acetate, ethyl lactate, and/or ethyl 3-hydroxypropanoate (ethyl 3-HP). In some embodiments of the present disclosure, the anhydride may be acetic anhydride. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/775632 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Separation B01D 3/009 (20130101) B01D 15/08 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Acyclic or Carbocyclic Compounds C07C 253/22 (20130101) Original (OR) Class C07C 253/22 (20130101) C07C 253/22 (20130101) C07C 255/04 (20130101) C07C 255/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046981 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jingwei Zhang (Fullerton, California); Jay D. Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jingwei Zhang (Fullerton, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/212515 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1048 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047024 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Xinghang Zhang (West Lafayette, Indiana); Qiang Li (West Lafayette, Indiana); Haiyan Wang (West Lafayette, Indiana); Sichuang Xue (West Lafayette, Indiana); Yifan Zhang (West Lafayette, Indiana) |
| ABSTRACT | A high-strength aluminum alloy coating. The coating includes aluminum, 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the 9R phase, the fine grains, and the stacking faults. A method of making a high-strength aluminum alloy coating on a substrate. The method includes, depositing the constituents of an aluminum alloy on a substrate such that the deposit forms a high-strength aluminum alloy coating containing 9R phase, fine grains, nanotwins, and stacking faults. A high-strength deformation layer in and on a casting of an aluminum alloy containing 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the PR phase, the fine grains, and the stacking faults. A method of making a high-strength deformation layer in and on a casting of an aluminum alloy by deforming the alloy such that deformation layer contains 9R phase, fine grains, nanotwins, and stacking faults. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/949436 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/016 (20130101) B32B 2307/536 (20130101) Alloys C22C 21/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12764 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047041 | Pocius et al. |
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| FUNDED BY |
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| APPLICANT(S) | SLT Technologies, Inc (Los Angeles, California) |
| ASSIGNEE(S) | SLT TECHNOLOGIES, INC. (Los Angeles, California) |
| INVENTOR(S) | Douglas W. Pocius (Santa Barbara, California); Derrick S. Kamber (Camas, Washington); Mark P. D'Evelyn (Vancouver, Washington); Jonathan D. Cook (Santa Barbara, California) |
| ABSTRACT | A process of preparing polycrystalline group III nitride chunks comprising the steps of (a) placing a group III metal inside a source chamber; (b) flowing a halogen-containing gas over the group III metal to form a group III metal halide; (c) contacting the group III metal halide with a nitrogen-containing gas in a deposition chamber containing a foil, the foil comprising at least one of Mo, W, Ta, Pd, Pt, Ir, or Re; (d) forming a polycrystalline group III nitride layer on the foil within the deposition chamber; (e) removing the polycrystalline group III nitride layer from the foil; and (f) comminuting the polycrystalline group III nitride layer to form the polycrystalline group III nitride chunks, wherein the removing and the comminuting are performed in any order or simultaneously. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 16/814813 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0632 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/60 (20130101) C01P 2004/90 (20130101) C01P 2006/80 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/303 (20130101) Original (OR) Class C23C 16/4401 (20130101) C23C 16/4488 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/105 (20130101) C30B 29/406 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047054 | Gregoire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | John M Gregoire (Sierra Madre, California); Lan Zhou (Pasadena, California); Santosh K. Suram (Pasadena, California); Aniketa A. Shinde (Duarte, California); Joel A. Haber (Pasadena, California); Dan W. Guevarra (Norwalk, California) |
| ABSTRACT | An oxygen evolution reaction catalyst is a ternary metal oxide that includes Mn and is represented by MnuSbvOw in the rutile crystal phase and MxMnyOz where M is selected from the group consisting of Ca, Ni, Sr, Zn, Mg, Ni, Ba, Co and where u/(u+v) is greater than 33%. |
| FILED | Thursday, April 19, 2018 |
| APPL NO | 15/957769 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4672 (20130101) C02F 1/46109 (20130101) C02F 2001/46133 (20130101) C02F 2001/46142 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) C25B 11/077 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047055 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peidong Yang (Kensington, California); Qiao Kong (El Cerrito, California); Dohyung Kim (Albany, California); Chong Liu (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peidong Yang (Kensington, California); Qiao Kong (El Cerrito, California); Dohyung Kim (Albany, California); Chong Liu (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to nanostructures. In one aspect, an array of nanowires is provided. The array of nanowires comprises a plurality of nanowires. End of nanowires of the plurality of nanowires are attached to a substrate. A liquid including a plurality of nanoparticles is deposited on the array of nanowires. The liquid is evaporated from the array of nanowires. Nanoparticles of the plurality of nanoparticles are deposited on the nanowires as a meniscus of the liquid recedes along lengths of the plurality of nanowires. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025594 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) C25B 11/091 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047248 | Sarawate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Neelesh Nandkumar Sarawate (Niskayuna, New York); Jonathan Dwight Berry (Simpsonville, South Carolina); Russell Pierson DeForest (Simpsonville, South Carolina); Kevin Weston McMahan (Greenville, South Carolina); Victor John Morgan (Simpsonville, South Carolina); Ibrahim Sezer (Greenville, South Carolina); Deepak Trivedi (Halfmoon, New York) |
| ABSTRACT | A flexible seal for sealing between two adjacent gas turbine components includes a forward end, an aft end axially separated from the forward end, and an intermediate portion between the forward end and the aft end. The intermediate portion defines a continuous curve in the circumferential direction, such that the aft end is circumferentially offset from the forward end. In other cases, the forward and aft ends are axially, radially, and circumferentially offset from one another. A method of sealing using the flexible seal includes inserting, in an axial direction, the aft end of the flexible seal into a recess defined by respective seal slots of two adjacent gas turbine components; and pushing the flexible seal in an axial direction through the recess until the forward end is disposed within the recess. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/012380 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/35 (20130101) F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/0887 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/46 (20130101) F23R 2900/00012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047360 | Houchens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Carsten Westergaard (Houston, Texas) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Carsten Westergaard (Houston, Texas) |
| INVENTOR(S) | Brent C. Houchens (Oakland, California); Myra L. Blaylock (Livermore, California); David Vaughn Marian (Stockton, California); David Charles Maniaci (Albuquerque, New Mexico); Carsten Westergaard (Houston, Texas) |
| ABSTRACT | An apparatus for energy extraction from fluid flow including an assembly including a plenum. The assembly further includes an aperture extending from an exterior surface to the plenum to allow flow therethrough. The apparatus further includes a channel including an inlet and an outlet in fluid communication with the plenum. The apparatus yet further includes an energy extraction device. The assembly is configured to create a pressure differential between the plenum and the inlet of the channel. The pressure differential causes fluid flow from the inlet of the channel to the plenum. The energy extraction device is configured to extract energy from the fluid flow. The apparatus additionally includes a control system configured to modify the pressure differential to control the fluid flow between the inlet of the channel and the plenum based on a characteristic of an exterior environment. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/182488 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines or Engines for Liquids F03B 3/04 (20130101) F03B 3/18 (20130101) F03B 11/02 (20130101) Wind Motors F03D 3/002 (20130101) F03D 3/005 (20130101) F03D 3/0463 (20130101) Original (OR) Class F03D 9/25 (20160501) F03D 9/28 (20160501) F03D 9/45 (20160501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047481 | Bidkar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Rahul Anil Bidkar (Niskayuna, New York); Steven Douglas Johnson (Milford, Ohio); Nathan Evan McCurdy Gibson (Cincinnati, Ohio) |
| ABSTRACT | A seal assembly of a rotary includes a radially oriented plate that axially opposes a front and rear support plates of a stator interface. The seal assembly also includes a film-riding shoe coupled with the radially oriented plate. The shoe forms a shoe fluid bearing between the shoe and a rotating component responsive to rotation of the rotating component and pressurization of fluid in the rotary machine upstream of the stator interface. One or more of the stator interface or the film-riding shoe includes one or more ports or pathways through which higher-pressure fluid upstream of the stator housing in the rotary machine flows to form an aft axial fluid bearing between the radially oriented plate and the rear support plate of the stator interface. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/296620 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) F01D 11/003 (20130101) F01D 11/08 (20130101) F01D 11/025 (20130101) Pistons; Cylinders; Sealings F16J 15/4476 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047529 | Kuczek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UTRC-IBD (East Hartford, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Andrzej Ernest Kuczek (Bristol, Connecticut); Ellen Y. Sun (South Windsor, Connecticut); Justin R. Hawkes (Marlborough, Connecticut); Paul F Croteau (Columbia, Connecticut); Wenping Zhao (Glastonbury, Connecticut) |
| ABSTRACT | A pressure vessel assembly includes a vessel having a wall defining a chamber and a circumferentially continuous lip projecting into the chamber from the wall. The lip defines a through-bore that is in fluid communication with the chamber. A nozzle assembly of the pressure vessel assembly includes a tube projecting at least in-part into the through-bore, and an o-ring disposed between, and in sealing contact with, the tube and the lip. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 16/095584 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/00 (20130101) F17C 1/16 (20130101) Original (OR) Class F17C 2201/0152 (20130101) F17C 2201/0166 (20130101) F17C 2201/0171 (20130101) F17C 2203/0604 (20130101) F17C 2203/0663 (20130101) F17C 2205/0305 (20130101) F17C 2209/2127 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047907 | Asaad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Sameh W. Asaad (Briarcliff Manor, New York); Mohit Kapur (Westchester, New York) |
| ABSTRACT | A method, system and computer program product are disclosed for using a Field Programmable Gate Array (FPGA) to simulate operations of a device under test (DUT). The DUT includes a device memory having a number of input ports, and the FPGA is associated with a target memory having a second number of input ports, the second number being less than the first number. In one embodiment, a given set of inputs is applied to the device memory at a frequency Fd and in a defined cycle of time, and the given set of inputs is applied to the target memory at a frequency Ft. Ft is greater than Fd and cycle accuracy is maintained between the device memory and the target memory. In an embodiment, a cycle accurate model of the DUT memory is created by separating the DUT memory interface protocol from the target memory storage array. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 16/656143 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2851 (20130101) G01R 31/3177 (20130101) G01R 31/31703 (20130101) Original (OR) Class G01R 31/31727 (20130101) Electric Digital Data Processing G06F 30/331 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048136 | Kalaev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dmitri Kalaev (Cambridge, Massachusetts); Harry L. Tuller (Wellesley, Massachusetts) |
| ABSTRACT | Reconfigurable, active optical components can flexibly manipulate light. One example of these components is an electro-chemo-optical device that utilizes a metal oxide film with a complex refractive index that varies as a function of an oxygen vacancy concentration. The optical device may include a metal oxide film, a first electrode, and a second electrode. The first electrode and the second electrode may be used to supply a bias voltage to induce a change in the oxygen vacancy concentration in order to change the optical properties (absorbance, transmittance, and/or reflectance) of the optical device. The magnitude and spatial distribution of the oxygen vacancy concentration may be altered to affect the optical properties of the optical device. In some designs, the optical device may also include an ionic conductor and oxygen source to supply/receive oxygen ions to/from the metal oxide film. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260860 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/163 (20130101) G02F 1/1524 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11048699 | Grider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Gary A. Grider (Los Alamos, New Mexico); Dominic Anthony Manno (Albuquerque, New Mexico); Wendy Kinton Poole (Los Alamos, New Mexico); David Bonnie (Los Alamos, New Mexico); Jeffrey Thornton Inman (Santa Fe, New Mexico) |
| ABSTRACT | Systems and methods are disclosed for a unified file index for a file system. In one example, a Grand Unified File Index (GUFI) includes a tree replicating the directory hierarchy of one or more primary filesystems, and individual metadata stores for each directory. The GUFI tree permits fast traversal, efficient user space access controls, and simple tree directed operations such as renames, moves, or permission changes. In some examples, the individual metadata stores can be implemented as embedded databases on flash storage for speed. In some examples, use of summary tables at the directory or subtree level can eliminate wasteful executions, prune tree traversal, and further improve performance. In various examples, efficient operation can be achieved from laptop to supercomputer scale, across a wide mix of file distributions and filesystems. |
| FILED | Thursday, March 14, 2019 |
| APPL NO | 16/353882 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/902 (20190101) G06F 16/908 (20190101) G06F 16/2246 (20190101) G06F 16/2272 (20190101) G06F 16/24532 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049623 | Barger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | BWXT mPower, Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Earl Brian Barger (Goode, Virginia); Scott L. Fitzner (Appomattox, Virginia); Jeffrey T. Lee (Blacksburg, Virginia); Roger D. Ridgeway (Lynchburg, Virginia) |
| ABSTRACT | A fuel rod for a nuclear reactor, including a cladding tube having a first end with an annular end face, a second end with an annular end face, and a cylindrical body portion extending therebetween, and a first tube end plug including a front portion, an annular lip with an annular end face, and a substantially straight cylindrical body portion extending therebetween, wherein the surface area of the annular end face of the first end of the cladding tube and the annular end face of the annular lip of the first tube end plug are substantially equal, and the annular end face of the first end of the cladding tube and the annular end face of the annular lip of the first tube end plug are connected by a resistance pressure weld. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/562986 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 11/002 (20130101) B23K 11/093 (20130101) B23K 33/006 (20130101) B23K 2101/06 (20180801) Nuclear Reactors G21C 3/10 (20130101) Original (OR) Class G21C 21/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049628 | Ehst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | David A. Ehst (Downers Grove, Illinois); James L. Willit (Batavia, Illinois) |
| ABSTRACT | A target unit for producing Cu67 radioisotope is described herein, and comprises a cage body releasably coupled to a screw-on cap; and a ceramic capsule containing a solid Zn68 target ingot and having one open end and one closed end and defining an interior chamber for the target ingot. The ceramic capsule is releasably contained between the cage body and the screw-on cap with a lid disposed on the open end of the capsule and a washer positioned between the lid and the screw-on cap. The screw-on cap and the washer provide a water-tight seal between the lid and the capsule. The interior of the capsule is in intimate physical contact with the target ingot; and the Zn68 of the target ingot is free of traces of residual oxygen that interfere with contact of the Zn68 to the capsule. |
| FILED | Monday, October 22, 2018 |
| APPL NO | 16/166441 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Separation B01D 7/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 1/12 (20130101) G21G 2001/0094 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050049 | Sacci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Robert L. Sacci (Ringgold, Georgia); Nancy J. Dudney (Knoxville, Tennessee); Lance W. Gill (Oak Ridge, Tennessee); Edward W. Hagaman (Oliver Springs, Tennessee); Gabriel M. Veith (Knoxville, Tennessee) |
| ABSTRACT | An electrode material includes a lithium active material composition. The lithium active material composition includes lithium and an active anode material. The lithium active material composition is coated with a lithium ion conducting passivating material, such that the electrode material is lithiated and pre-passivated. An electrode and a battery are also disclosed. Methods of making an electrode material, electrode and battery that are lithiated and pre-passivated are also disclosed. |
| FILED | Wednesday, February 13, 2019 |
| APPL NO | 16/274714 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/62 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/139 (20130101) H01M 4/366 (20130101) H01M 4/0404 (20130101) H01M 4/0445 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050062 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ke-Ji Pan (Ellicott City, Maryland); Mohammed Hussain Abdul Jabbar (College Park, Maryland); Dong Ding (Idaho Falls, Idaho); Eric Wachsman (Fulton, Maryland) |
| ASSIGNEE(S) | REDOX POWER SYSTEMS, LLC (College Park, Maryland); UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Ke-Ji Pan (Ellicott City, Maryland); Mohammed Hussain Abdul Jabbar (College Park, Maryland); Dong Ding (Idaho Falls, Idaho); Eric Wachsman (Fulton, Maryland) |
| ABSTRACT | In various embodiments, a solid oxide fuel cell is fabricated in part by disposing a functional layer between the cathode and the solid electrolyte. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/211494 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/0254 (20130101) B05D 7/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8663 (20130101) Original (OR) Class H01M 4/9033 (20130101) H01M 4/9066 (20130101) H01M 8/126 (20130101) H01M 8/1213 (20130101) H01M 8/1246 (20130101) H01M 8/1253 (20130101) H01M 2008/1293 (20130101) H01M 2250/30 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050075 | Vajo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | John J. Vajo (West Hills, California); Jason A. Graetz (Calabasas, California); Channing Ahn (Pasadena, California); Dan Addison (Los Angeles, California); Hongjin Tan (Monterey Park, California); Jasim Uddin (Santa Clarita, California) |
| ABSTRACT | In some variations, a hydrogen-storage material formulation comprises: a solid hydrogen-storage material containing at least one metal and hydrogen that is bonded with the metal; and a liquid electrolyte that is ionically conductive for at least one ion derived from the hydrogen-storage material. The liquid electrolyte may be from 5 wt % to about 20 wt % of the hydrogen-storage material formulation, for example. Many materials are possible for both the hydrogen-storage material as well as the liquid electrolyte. The hydrogen-storage material has a higher hydrogen evolution rate in the presence of the liquid electrolyte compared to a hydrogen-storage material without the liquid electrolyte. This is experimentally demonstrated with a destabilized metal hydride, MgH2/Si system, incorporating a LiI—KI—CsI ternary eutectic salt as the liquid electrolyte. Inclusion of the liquid electrolyte gives a ten-fold increase in H2 evolution rate at 250° C., reaching 3.5 wt % hydrogen released in only 7 hours. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 15/928194 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/143 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050076 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wei Wang (Kennewick, Washington); Zimin Nie (Richland, Washington); Vincent Sprenkle (Richland, Washington); Jamelyn D. Holladay (Kennewick, Washington) |
| ABSTRACT | Flow cell systems are provided. Example flow cell systems can include an H+/H2 half-cell and a counterpart Fe3+/Fe2+ or V5+/V4+ half-cell. Flow cell systems can also include a half-cell in fluid communication with an electrolyte regeneration chamber. Embodiments of these flow cells systems can be configured to produce hydrogen through electrolysis. Flow cell battery systems are also disclosed. Example flow cell battery systems can include an H+/H2 analyte; and a counterpart Fe3+/Fe2+ or V5+/V4+ catholyte. Processes for generating hydrogen are also disclosed. Example processes can include generating protons from a Fe3+/Fe2+ or V5+/V4+ electrolyte solution; and reacting the protons with H2O to form H2. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/004717 |
| ART UNIT | 1796 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 5/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050078 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wei Wang (Kennewick, Washington); Dongping Lu (Richland, Washington); Yuyan Shao (Richland, Washington); Qian Huang (Richland, Washington) |
| ABSTRACT | Described herein are systems and methods of hydrogen generation and electrolyte regeneration as independent operations in separate redox flow cells. The operations can be decoupled by using an energy-bearing redox pair that electrochemically bears energy facilitating flexible, efficient hydrogen generation. In one example, the hydrogen generation redox flow cell can include a liquid, energy-bearing electrolyte solution in which at least one species of an energy-bearing redox pair is dissolved, to decouple the hydrogen evolution reaction from the reaction at the opposite electrode (e.g., the oxygen evolution reaction of conventional direct water electrolysis). Each species of the energy-bearing redox pair is associated with a standard electrode potential within the water electrolysis window. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 15/988213 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/73 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/186 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 8/04925 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050094 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Carter W. Abney (Califon, New Jersey); Richard T. Mayes (Knoxville, Tennessee); Dmitriy Dolzhnikov (Oak Ridge, Tennessee); Huimin Luo (Knoxville, Tennessee) |
| ABSTRACT | A heat transfer (exchange) composition comprising a halide salt matrix having dispersed therein nanoparticles comprising elemental carbon in the absence of water and surfactants, wherein said halide is fluoride or chloride, wherein the halide salt may be an alkali halide salt (e.g., lithium fluoride, sodium fluoride, potassium fluoride, rubidium fluoride, sodium chloride, potassium chloride, rubidium chloride, and eutectic mixtures thereof) or an alkaline earth halide salt (e.g., fluoride or chloride salt of beryllium, magnesium, calcium, strontium, or barium), and wherein the nanoparticles comprising elemental carbon may be solid or hollow, and wherein the composition may further include nanoparticles comprising a fissile material (e.g., U, Th, or Pu) dispersed within the composition. Molten salt reactors (MSRs) containing these heat transfer compositions in coolant loops in thermal exchange with a reactor core, as well operation of such MSRs, are also described. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039770 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 307/68 (20130101) Nuclear Reactors G21C 1/02 (20130101) G21C 3/54 (20130101) G21C 11/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/399 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050114 | Tsutsui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Waterloo Tsutsui (West Lafayette, Indiana); Yuezhong Feng (Henan, China PRC); Weinong Wayne Chen (West Lafayette, Indiana); Thomas Heinrich Siegmund (West Lafayette, Indiana) |
| ABSTRACT | Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials. |
| FILED | Sunday, August 18, 2019 |
| APPL NO | 16/543599 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Fire-fighting A62C 3/07 (20130101) A62C 3/16 (20130101) A62C 99/0045 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/20 (20210101) H01M 50/24 (20210101) Original (OR) Class H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050119 | Carlson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OPTODOT CORPORATION (Devens, Massachusetts) |
| ASSIGNEE(S) | Optodot Corporation (Devens, Massachusetts) |
| INVENTOR(S) | Steven A. Carlson (Cambridge, Massachusetts); Benjamin Sloan (Exeter, New Hampshire); David W. Avison (Boxborough, Massachusetts) |
| ABSTRACT | Provided is a lithium battery, wherein the battery comprises an anode, a cathode, wherein the cathode comprises one or more transition metals, an electrolyte, and a porous separator interposed between the cathode and anode, wherein the separator comprises an anionic compound. Also provided are methods of manufacturing such batteries. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 16/404015 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/20 (20130101) H01G 11/50 (20130101) H01G 11/52 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0585 (20130101) H01M 50/46 (20210101) H01M 50/446 (20210101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050262 | Schoenwald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Montana Technological University (Butte, Montana) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Montana Technological University (Butte, Montana) |
| INVENTOR(S) | David A. Schoenwald (Albuquerque, New Mexico); Raymond H. Byrne (Albuquerque, New Mexico); Ryan Thomas Elliott (Seattle, Washington); Jason C. Neely (Albuquerque, New Mexico); Brian Joseph Pierre (Albuquerque, New Mexico); Felipe Wilches-Bernal (Albuquerque, New Mexico); Daniel J. Trudnowski (Butte, Montana) |
| ABSTRACT | The present invention relates to PMU-based control systems for dampening inter-area oscillations in large-scale interconnected power systems or grids to protect against a catastrophic blackout. The control systems receive phasor measurements from two or more locations on an AC transmission line and generates a power control command to a power resource on the grid. |
| FILED | Tuesday, March 20, 2018 |
| APPL NO | 15/926658 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/26 (20130101) H02J 3/32 (20130101) H02J 3/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051387 | Watson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Scott Avery Watson (Jemez Springs, New Mexico); Nicola Maree Winch (Los Alamos, New Mexico); David Platts (Los Alamos, New Mexico); Samuel A. Salazar (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus includes an electromechanical x-ray generator (MEXRAY) configured to charged capacitors using a small, high-voltage direct current. The apparatus also includes an ultraviolet (UV) light emitting diode (LED) driven photocathode device configured to control/modulate an electron dose rate of the MEXRAY or other vacuum DC, source. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661946 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 35/065 (20130101) X-ray Technique H05G 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051428 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Jinliang Wang (Ellington, Connecticut); Suman Dwari (Vernon, Connecticut) |
| ABSTRACT | Disclosed is a thermal management system for removing heat from a power electronic heat source, the system comprising: a base plate having a plurality of fluid passages there through and extending between and inlet side of the base plate and an outlet side of the base plate; and a plurality of heat transfer pipe segments respectively attached to one or more of the plurality of fluid passages at the inlet side of the base plate and the outlet side of the base plate, the plurality of heat transfer pipe segments arranged adjacent one another, the plurality of heat transfer pipe segments containing a two-phase working fluid, and the plurality of heat transfer pipe segments forming a continuous flow path through and back into the base plate for the two-phase working fluid. |
| FILED | Thursday, October 31, 2019 |
| APPL NO | 16/670043 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) H01L 25/072 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20327 (20130101) H05K 7/20336 (20130101) Original (OR) Class H05K 7/20936 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11045132 | Makeyev |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Diné College (Tsaile, Arizona) |
| ASSIGNEE(S) | Diné College (Tsaile, Arizona) |
| INVENTOR(S) | Oleksandr Makeyev (Tsaile, Arizona) |
| ABSTRACT | An electrode device for electrophysiological measurement may include an electrode substrate having a surface area. The electrode device may include a central electrode disposed on the electrode substrate around a central portion of the surface area. The electrode device may include a plurality of electrodes disposed on the electrode substrate concentric with the central electrode. The plurality of electrodes may include a first electrode covering a first portion of the surface area of the electrode substrate and a second electrode covering a second portion of the surface area of the electrode substrate. The second portion may be greater than a combined surface area of the first portion and the central portion. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/067480 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) Original (OR) Class A61B 2562/04 (20130101) A61B 2562/0209 (20130101) A61B 2562/0215 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045427 | John et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
| ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | Vijay John (Destrehan, Louisiana); Gary McPherson (Mandeville, Louisiana) |
| ABSTRACT | The present invention discloses the morphology of hollow, double-shelled submicrometer particles generated through a rapid aerosol-based process. The inner shell is an essentially hydrophobic carbon layer of nanoscale dimension (5-20 nm), and the outer shell is a hydrophilic silica layer of approximately 5-40 nm, with the shell thickness being a function of the particle size. The particles are synthesized by exploiting concepts of salt bridging to lock in a surfactant (CTAB) and carbon precursors together with iron species in the interior of a droplet. This deliberate negation of surfactant templating allows a silica shell to form extremely rapidly, sealing in the organic species in the particle interior. Subsequent pyrolysis results in a buildup of internal pressure, forcing carbonaceous species against the silica wall to form an inner shell of carbon. The incorporation of magnetic iron oxide into the shells opens up applications in external stimuli-responsive nanomaterials. |
| FILED | Tuesday, September 05, 2017 |
| APPL NO | 15/695387 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/501 (20130101) A61K 9/5089 (20130101) Original (OR) Class A61K 9/5094 (20130101) A61K 9/5192 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) B01J 13/22 (20130101) B01J 21/18 (20130101) B01J 21/063 (20130101) B01J 23/745 (20130101) B01J 35/002 (20130101) B01J 35/004 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 35/026 (20130101) B01J 35/0033 (20130101) B01J 35/1057 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 37/08 (20130101) B01J 37/0072 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/34 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/62 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) C09B 61/00 (20130101) C09B 67/0008 (20130101) C09B 67/0097 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) C09C 1/30 (20130101) C09C 1/407 (20130101) C09C 1/3607 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2031 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/587 (20130101) H01M 4/8605 (20130101) H01M 4/8657 (20130101) H01M 4/9041 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11045548 | El-Sayed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Mostafa A. El-Sayed (Atlanta, Georgia); Moustafa R. K. Ali (Atlanta, Georgia) |
| ABSTRACT | A method of inhibiting migration of a cancer cell of a tumor in a subject comprising the steps of: (a) contacting the tumor with a gold nanomaterial; and (b) irradiating the tumor with an irradiation source. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/029193 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 33/242 (20190101) A61K 41/0052 (20130101) Original (OR) Class A61K 47/62 (20170801) A61K 47/64 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0613 (20130101) A61N 2005/067 (20130101) A61N 2005/0658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046826 | Gin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Douglas L. Gin (Longmont, Colorado); Richard D. Noble (Boulder, Colorado); Sarah Marie Dischinger (Boulder, Colorado); Blaine M. Carter (Nampa, Idaho) |
| ABSTRACT | The invention includes methods of reversibly tuning the effective pore size and/or solute rejection selectivity of a nanoporous lyotropic liquid crystal (LLC) polymer membrane. The membranes of the invention have high levels of pore size uniformity, allowing for size discrimination separation, and may be used for separation processes such as liquid-phase separations. |
| FILED | Thursday, January 25, 2018 |
| APPL NO | 15/879902 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 61/027 (20130101) B01D 67/0006 (20130101) B01D 67/009 (20130101) B01D 67/0088 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/125 (20130101) B01D 71/82 (20130101) B01D 2323/30 (20130101) B01D 2323/34 (20130101) B01D 2323/46 (20130101) B01D 2323/345 (20130101) B01D 2325/16 (20130101) B01D 2325/021 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/07 (20170101) B01J 41/14 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 27/28 (20130101) B32B 2250/02 (20130101) B32B 2250/22 (20130101) B32B 2266/0221 (20130101) B32B 2305/026 (20130101) B32B 2305/55 (20130101) B32B 2355/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 36/22 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) C08J 5/2287 (20130101) Original (OR) Class C08J 9/36 (20130101) C08J 2347/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/02 (20130101) C09K 19/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046828 | Yi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Hyunmin Yi (Lexington, Massachusetts); Sukwon Jung (Incheon, South Korea) |
| ABSTRACT | A macroporous polymeric hydrogel microsphere that contains poly(ethylene glycol), chitosan, and water. The hydrogel microsphere, having a diameter of 50-250 μm and a mesh size of 5-100 nm, is capable of transporting biomolecules conjugated to it. Also disclosed is a method of fabricating the microsphere based on a micromolding technique utilizing surface tension-induced droplet formation followed by photo-induced polymerization. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/568267 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1652 (20130101) A61K 47/6925 (20170801) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 67/20 (20130101) B29C 2035/0827 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2071/02 (20130101) B29K 2105/0061 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 3/246 (20130101) C08J 9/0061 (20130101) Original (OR) Class C08J 2205/022 (20130101) C08J 2207/10 (20130101) C08J 2371/02 (20130101) C08J 2405/08 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046854 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David M. Lynn (Middleton, Wisconsin); Uttam Manna (Guwahati, India) |
| ABSTRACT | The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/740008 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/73 (20130101) Heterocyclic Compounds C07D 235/28 (20130101) C07D 235/30 (20130101) C07D 307/12 (20130101) C07D 307/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 5/1625 (20130101) C09D 7/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046981 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jingwei Zhang (Fullerton, California); Jay D. Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jingwei Zhang (Fullerton, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/212515 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1048 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046991 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Jared L. Anderson (Ames, Iowa); Kevin D. Clark (Ames, Iowa) |
| ABSTRACT | In this disclosure, transition and rare earth metal-based magnetic ionic liquids (MILs) are successfully prepared in a two-step synthesis and used to extract viable bacteria from a liquid sample. The disclosed MILs are extremely hydrophobic MILs and were insoluble in aqueous solution at 0.01% (v/v). Furthermore, these MILs were miscible in a variety of polar and non-polar organic solvents. Moreover, these MILs possess low viscosity and increased magnetic susceptibility. These MILs possess unique characteristics that can have great potential uses in various chemical applications such as extraction solvents in LLE, liquid electrochromic materials (Co-based MILs), and novel reaction media for organic synthesis. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 15/950916 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Original (OR) Class C12Q 1/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48735 (20130101) G01N 33/54333 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/42 (20130101) H01F 1/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047232 | Knight et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biota Technology, Inc. (Oakland, California) |
| ASSIGNEE(S) | Biota Technology, Inc (San Diego, California) |
| INVENTOR(S) | Rob Knight (San Diego, California); Ajay Kshatriya (Oakland, California); John Ely (Houston, Texas); James Prestidge, Jr. (Cypress, Texas); Paul Henshaw (Clayton, California); Chris Lauber (Boulder, Colorado); J. Gregory Caporaso (Flagstaff, Arizona); Dan Knights (St. Paul, Minnesota); Ryan Gill (Denver, Colorado); Joel Moxley (Highlands Ranch, Colorado) |
| ABSTRACT | There are provided methods, systems and processes for the utilization of microbial and related genetic information for use in the exploration, determination, production and recovery of natural resources, including energy sources, and the monitoring, control and analysis of processes and activities. |
| FILED | Tuesday, December 30, 2014 |
| APPL NO | 14/586865 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/62 (20130101) C09K 8/582 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6874 (20130101) C12Q 1/6888 (20130101) C12Q 2600/156 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 21/065 (20130101) E21B 43/00 (20130101) E21B 43/26 (20130101) E21B 43/267 (20130101) E21B 47/11 (20200501) E21B 49/00 (20130101) E21B 49/003 (20130101) E21B 49/08 (20130101) Original (OR) Class E21B 49/086 (20130101) E21B 49/0875 (20200501) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 9/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 20/00 (20190201) G16B 40/00 (20190201) G16B 45/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047458 | Hasara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven Lawrence Hasara (Bradenton, Florida); Craig Perry Lusk (Lutz, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Steven Lawrence Hasara (Bradenton, Florida); Craig Perry Lusk (Lutz, Florida) |
| ABSTRACT | A compliant crank slider with adjustable constant-force output. Constant-force mechanisms (CFM) are used to maintain a constant output reaction force throughout a large range of compressive motion. The invention improves on existing CFM by introducing a second degree of freedom that adjusts the mechanism's output without changing its kinematic structure. This second degree of freedom is the rotation of a compliant beam about its longitudinal axis as it is constrained to the initial plane of bending. In an embodiment, the second degree of freedom is the rotation of both a first compliant beam and a second compliant beam. The resulting change in the constant force mechanism allows for adjustment to a specifiable range of constant-force outputs. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661465 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 17/0208 (20130101) Gearing F16H 21/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047794 | Hutchens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (Stillwater, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Chriswell G. Hutchens (Stillwater, Oklahoma); Cheng Hao (Stillwater, Oklahoma); Aihua Xie (Stillwater, Oklahoma); Johnny Hendriks (Amsterdam, Netherlands) |
| ABSTRACT | A system and method that improves and enhances the quality of step-scan Fourier Transform Infrared spectroscopy data. The system and method enables the removal of dark voltage with greater accuracy, provides access to previously unobtainable IR spectral information data which is amplified by the disclosed system and method. The system and method removes dark interferogram voltage from an interferogram of interest obtained during nanosecond or microsecond step-scan measurement. The system and method includes a programmable high gain setting to amplify both signal and noise into the analog-to-digital quantization range to allow signal averaging for obtaining additional bits of resolution. The system and method also accounts for and corrects intrinsic offset voltages introduced by the electronics of the disclosed system. The system and method enable precise interferogram measurement and post-laser excitation or provision for other stimuli that result in a material change of state exploration in nanosecond or microsecond speed. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 16/488840 |
| ART UNIT | 2896 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/274 (20130101) Original (OR) Class G01N 2021/3595 (20130101) G01N 2201/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049476 | Fuchs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Henry Fuchs (Chapel Hill, North Carolina); Anselmo A. Lastra (Chapel Hill, North Carolina); John Turner Whitted (Pittsboro, North Carolina); Feng Zheng (Chapel Hill, North Carolina); Andrei State (Chapel Hill, North Carolina); Gregory Welch (Longwood, Florida) |
| ABSTRACT | Methods, systems, and computer readable media for minimal-latency tracking and display for matching real and virtual worlds in head-worn displays are disclosed. According to one aspect, a method for minimal-latency tracking and display for matching real and virtual worlds in head-worn displays includes calculating a desired image, calculating an error image as the difference between the desired image and an image currently being perceived by a user, identifying as an error portion a portion of the error image having the largest error, updating a portion of a projected image that corresponds to the error portion, and recalculating the image currently being perceived by a user based on the updated projected image. |
| FILED | Wednesday, November 04, 2015 |
| APPL NO | 15/522765 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0101 (20130101) G02B 27/0176 (20130101) G02B 2027/014 (20130101) G02B 2027/0178 (20130101) Electric Digital Data Processing G06F 3/147 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/377 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049562 | Giles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ellis Robinson Giles (Houston, Texas); Peter Joseph Varman (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ellis Robinson Giles (Houston, Texas); Peter Joseph Varman (Houston, Texas) |
| ABSTRACT | Emerging byte-addressable persistent memory technologies, generically referred to as Storage Class Memory, offer performance advantages and access similar to Dynamic Random Access Memory while having the persistence of disk. Unifying storage and memory into a memory tier that can be accessed directly requires additional burden to ensure that groups of memory operations to persistent or nonvolatile memory locations are performed sequentially, atomically, and not caught in the cache hierarchy. The present invention provides a lightweight solution for the atomicity and durability of write operations to nonvolatile memory, while simultaneously supporting fast paths through the cache hierarchy to memory. The invention includes a hardware-supported solution with modifications to the memory hierarchy comprising a victim cache and additional memory controller logic. The invention also includes a software only method and system that provides atomic persistence to nonvolatile memory using a software alias in DRAM and log in nonvolatile memory. |
| FILED | Monday, December 24, 2018 |
| APPL NO | 16/231939 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/06 (20130101) G06F 12/0815 (20130101) Static Stores G11C 11/15 (20130101) G11C 13/0002 (20130101) G11C 14/0045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11049697 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Fraunhofer USA (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Fraunhofer USA (East Lansing, Michigan) |
| INVENTOR(S) | Qi Hua Fan (Okemos, Michigan); Thomas Schuelke (Pinckney, Michigan); Lars Haubold (East Lansing, Michigan); Michael Petzold (Flint, Michigan) |
| ABSTRACT | A single beam plasma or ion source apparatus is provided. Another aspect employs an ion source including multiple magnets and magnetic shunts arranged in a generally E cross-sectional shape. A further aspect of an ion source includes magnets and/or magnetic shunts which create a magnetic flux with a central dip or outward undulation located in an open space within a plasma source. In another aspect, an ion source includes a removeable cap attached to an anode body which surrounds the magnets. Yet a further aspect provides a single beam plasma source which generates ions simultaneously with target sputtering and at the same internal pressure. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/642133 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/3405 (20130101) H01J 37/32422 (20130101) Original (OR) Class H01J 37/32669 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050031 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hong Koo Kim (Wexford, Pennsylvania); Daud Hasan Emon (Hillsboro, Oregon) |
| ABSTRACT | Various light emitting diode device embodiments that include emissive material elements, e.g., core-shell quantum dots, that are either (i) provided in nanoscale holes provided in an insulating layer positioned between an electron supply/transport layer and a hole supply/transport layer, or (ii) provided on a suspension layer positioned above and covering a nanoscale hole in such an insulating layer. Also, various methods of making such light emitting diode devices, including lithographic and non-lithographic methods. |
| FILED | Thursday, October 17, 2019 |
| APPL NO | 16/655389 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/3246 (20130101) H01L 51/0037 (20130101) H01L 51/0042 (20130101) H01L 51/50 (20130101) Original (OR) Class H01L 51/52 (20130101) H01L 51/56 (20130101) H01L 51/0096 (20130101) H01L 51/502 (20130101) H01L 51/5004 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050114 | Tsutsui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Waterloo Tsutsui (West Lafayette, Indiana); Yuezhong Feng (Henan, China PRC); Weinong Wayne Chen (West Lafayette, Indiana); Thomas Heinrich Siegmund (West Lafayette, Indiana) |
| ABSTRACT | Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials. |
| FILED | Sunday, August 18, 2019 |
| APPL NO | 16/543599 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Fire-fighting A62C 3/07 (20130101) A62C 3/16 (20130101) A62C 99/0045 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/20 (20210101) H01M 50/24 (20210101) Original (OR) Class H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050449 | Pekoz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Berker Pekoz (Tampa, Florida); Selcuk Kose (Pittsford, New York); Huseyin Arslan (Tampa, Florida) |
| ABSTRACT | A system and method for frame structure compliant adaptive extensionless windowing that maximizes fair proportional network capacity in the download. Gains are provided by emulating the multipath multiple access channel to the base station to calculate almost-optimum transmitter windowing durations prior to transmission and using the variance of received symbols using different window durations to allow the user equipment nodes to estimate optimal receiver windowing durations without calculations requiring further knowledge about the network. |
| FILED | Wednesday, November 06, 2019 |
| APPL NO | 16/675888 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/1027 (20130101) Original (OR) Class H04B 1/1036 (20130101) H04B 17/336 (20150115) H04B 2001/1045 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 25/03834 (20130101) H04L 27/264 (20130101) H04L 27/2607 (20130101) H04L 27/2614 (20130101) H04L 27/2628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050457 | Mangal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vivek Mangal (New York, New York); Peter R. Kinget (Summit, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Vivek Mangal (New York, New York); Peter R. Kinget (Summit, New Jersey) |
| ABSTRACT | Circuits for continuous-time analog correlators are provided, comprising: a first VCO that receives an input signal and that outputs a first pulse frequency modulated (PFM) output signal; a second VCO that receives a reference signal and that outputs a second PFM output signal; a first phase frequency detector (PFD) that receives the first PFM output signal and the second PFM output signal and that produces a first PFD output signal; a first delay cell that receives the first PFM output signal and that produces a first delayed signal (DS); a second delay cell that receives the second PFM output signal and that produces a second DS; a second PFD that receives the first DS and the second DS and that produces a second PFD output signal; and a capacitor-digital-to-analog converter (capacitor-DAC) that receives the first PFD output signal and the second PFD output signal and that produces a correlator output. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 16/889716 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Demodulation or Transference of Modulation From One Carrier to Another H03D 7/165 (20130101) Coding; Decoding; Code Conversion in General H03M 1/468 (20130101) H03M 1/804 (20130101) Transmission H04B 1/709 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050995 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Song Zhang (West Lafayette, Indiana); Tyler Bell (Lafayette, Indiana) |
| ABSTRACT | A method for generating encoded depth data includes receiving digital fringe projection (DFP) data corresponding to a three-dimensional structure of a physical object, and generating first and second fringe encodings for a first predetermined wavelength based on the DFP data at a first coordinate. The method further includes generating third and fourth fringe encodings for a second predetermined wavelength based on the DFP data at the first coordinate, the second wavelength being longer than the first wavelength, and generating a combined fringe encoding based on the third fringe encoding and the fourth fringe encoding. The method further includes storing the first, second, and combined fringe encoding data in a pixel of two-dimensional image data at a pixel coordinate in the two-dimensional image data corresponding to the first coordinate. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826573 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2513 (20130101) Pictorial Communication, e.g Television H04N 13/15 (20180501) H04N 13/139 (20180501) H04N 13/161 (20180501) Original (OR) Class H04N 13/254 (20180501) H04N 19/625 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051270 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Tian He (Arden Hills, Minnesota); Song Liu (Minneapolis, Minnesota) |
| ABSTRACT | A 3D digital indoor localization system uses light emitting diode (LED) lighting infrastructures for localization. In one example approach, a light source includes a convex lens and an array of LEDs, all configured as a single LED lamp. The localization system exploits the light splitting properties of the convex lens to create a one-to-one mapping between a location and the set of orthogonal digital light signals received from particular LEDs of the LED lamp. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179649 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/0266 (20130101) G01J 1/0411 (20130101) G01J 2001/4252 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/00 (20130101) Transmission H04B 10/116 (20130101) H04B 10/502 (20130101) H04B 10/5563 (20130101) Selecting H04Q 11/0005 (20130101) Wireless Communication Networks H04W 64/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11046430 | Melton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | John Earl Melton (Hollister, California); Ben Edward Nikaido (Gilroy, California) |
| ABSTRACT | Systems and methods are provided for improving the flight safety of fixed- and rotary-wing unmanned aerial systems (UAS) operating in complex dynamic environments, including urban cityscapes. Sensors and computations are integrated to predict local winds and promote safe operations in dynamic urban regions where GNSS and other network communications may be unavailable. The system can be implemented onboard a UAS and does not require in-flight communication with external networks. Predictions of local winds (speed and direction) are created using inputs from sensors that scan the local environment. These predictions are then used by the UAS guidance, navigation, and control (GNC) system to determine safe trajectories for operations in urban environments. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955661 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class B64C 2201/141 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/101 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 2207/10032 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) Traffic Control Systems G08G 5/0034 (20130101) G08G 5/0039 (20130101) G08G 5/0069 (20130101) G08G 5/0091 (20130101) Pictorial Communication, e.g Television H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047034 | Harder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Bryan J. Harder (Bay Village, Ohio); Michael P. Schmitt (Cleveland, Ohio); Brian S. Good (Cleveland, Ohio) |
| ABSTRACT | Oxide coatings deposited by plasma spray-physical vapor deposition (PS-PVD) can be processed to be mechanically tough (erosion resistant) and electrically conductive at room temperature. The electrically conductive phase contained within the oxide (MO2) coatings is a metastable suboxide (MO) that has not been formed in significant volume under any other known methods. Content of the electrically conductive phase can be varied in addition to the microstructure, which can be columnar, planar, or a combination of the two depending on the processing conditions. Upon exposing the material to moderate temperatures (>300° C.), the metastable phase is further oxidized (to MO2), and the material becomes insulating, but retains its high toughness and microstructure. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883551 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/11 (20160101) Original (OR) Class C23C 4/134 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047132 | Turse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roccor, LLC (Longmont, Colorado) |
| ASSIGNEE(S) | Roccor, LLC (Longmont, Colorado) |
| INVENTOR(S) | Dana Turse (Broomfield, Colorado); Larry Adams (Thornton, Colorado); William Francis (Lyons, Colorado) |
| ABSTRACT | Device, systems, and methods for boom deployment and/or boom stowage are provided in accordance with various embodiments. Some embodiments may facilitate root control of a boom utilizing a variety of tools and techniques. Some embodiments may facilitate boom tip control. Some embodiments may include a boom and a boom spool. Some embodiments include one or more devices that may include: one or more compliant components, one or more boom spreaders, one or more stabilizing tabs, one or more spool locks, one or more boom tip guides, one or more root clamps, and/or a single consolidation roller. Some embodiments include methods that may utilize one or more of the noted devices. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/424130 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) Structural Elements; Building Materials E04C 3/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047251 | Banham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Christopher Banham (Indianapolis, Indiana); Rex M. Little (Indianapolis, Indiana) |
| ABSTRACT | Gas turbine engines which include electrical motor-generator assemblies arranged near the fan outlet include electrical cable routing assemblies extending through a bypass flow path. Directing the electrical cables through a king guide vane can consolidate routing requirements while accessing each of electrical windings of the electrical machine. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514258 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 15/10 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/76 (20130101) Dynamo-electric Machines H02K 5/225 (20130101) H02K 7/1823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047670 | Terentiev |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexandre N. Terentiev (Santa Rosa, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandre N. Terentiev (Santa Rosa, California) |
| ABSTRACT | A system and apparatus are provided for use in determining a spacing of a gap between a first flange and a second flange connected by at least one bolt using an integrated sensor. The sensor may include a plurality of electric coils for generating an AC magnetic field for causing a magnetic material to produce a dynamic mechanical response as a result of a change in the spacing of the first and second flanges. A holder for the sensor may be provided, and may be adapted for positioning between the joined parts or the associated flanges, and further may be adapted to attach to a bolt connecting the parts. Related methods include estimating a retained load on a gasket or seal associated with the first and second flanges. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950091 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/24 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/2046 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047750 | Ryu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New Mexico Tech University Research Park Corporation (Socorro, New Mexico) |
| ASSIGNEE(S) | New Mexico Tech University Research Park Corporation (Socorro, New Mexico) |
| INVENTOR(S) | Donghyeon Ryu (Socorro, New Mexico) |
| ABSTRACT | Disclosed herein is a composition and a method for energy harvesting and the autonomous detection of structural failure. This method can be used to monitor, for example, the structural integrity of unmanned aircraft systems. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293259 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/082 (20130101) H01L 41/193 (20130101) H01L 41/1132 (20130101) H01L 51/004 (20130101) H01L 51/0035 (20130101) H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/0047 (20130101) H01L 51/0048 (20130101) H01L 51/0094 (20130101) H01L 51/5287 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051187 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Anaheim, California) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Friday, December 27, 2019 |
| APPL NO | 16/728397 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11045672 | Detweiler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUTECH VENTURES (Lincoln, Nebraska) |
| INVENTOR(S) | Carrick Detweiler (Lincoln, Nebraska); Sebastian Elbaum (Lincoln, Nebraska); James Higgins (Lincoln, Nebraska); Christian Laney (Papillion, Nebraska); Craig Allen (Crete, Nebraska); Dirac Twidwell (Lincoln, Nebraska); Evan Michael Beachly (Lincoln, Nebraska) |
| ABSTRACT | An unmanned aerial vehicle (UAV) can be configured for fire suppression and ignition. In some examples, the UAV includes an aerial propulsion system, an ignition system, and a control system. The ignition system includes a container of delayed-ignition balls and a dropper configured, by virtue of one or more motors, to actuate and drop the delayed-ignition balls. The control system is configured to cause the UAV to fly to a site of a prescribed burn and, while flying over the site of the prescribed burn, actuate one or more of the delayed-ignition balls. After actuating the one or more delayed-ignition balls, the UAV drops the actuated one or more delayed-ignition balls from the UAV onto the site of the prescribed burn. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/768768 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fire-fighting A62C 3/025 (20130101) Original (OR) Class Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/024 (20130101) B64C 2201/027 (20130101) B64C 2201/123 (20130101) B64C 2201/141 (20130101) B64C 2201/146 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/02 (20130101) B64D 1/16 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0016 (20130101) G05D 1/0038 (20130101) G05D 1/0055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11046994 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Wei Zhao (Port St. Lucie, Florida); Elizabeth A Baldwin (Winter Haven, Florida); Jinhe Bai (Port St. Lucie, Florida); Anne Plotto (Winter Haven, Florida) |
| ABSTRACT | A novel method for isolating DNA from juices and ciders is described. This method is low cost and yield large quantities of highly purified DNA even though one uses a small quantity of juice or cider. A method for determining if a juice or cider is safe to consume and/or the quality of the juice or cider are also described. For these methods, one can perform qPCR on the DNA which can be obtained using the disclosed method or any other prior art method, and comparing the amount of DNA from microorganisms is present in the juice and/or cider to determine the safety and/or quality of the juice and/or cider. These methods work even if the liquid was pasteurized. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/027686 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6888 (20130101) C12Q 2531/113 (20130101) C12Q 2561/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11045474 | Gavegnano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States Government as Repersentative by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Christina Gavegnano (Decatur, Georgia); Raymond F. Schinazi (Miami, Florida) |
| ABSTRACT | Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidine JAK inhibitors. Combinations of these JAK inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of HIV in an infected patient. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 16/816901 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/66 (20130101) A61K 31/513 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/536 (20130101) A61K 31/4045 (20130101) A61K 31/4045 (20130101) A61K 31/7072 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047009 | Niculescu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Alexander B. Niculescu (Indianapolis, Indiana) |
| ABSTRACT | Biomarkers and methods for screening expression levels of the biomarkers for predicting and tracking suicidality, as well as for monitoring response to a treatment for suicidal risk and for determining suicidal risk as a side-effect of an antidepressant are disclosed. |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/091706 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/9466 (20130101) G01N 2800/52 (20130101) G01N 2800/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11048313 | Jana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Siddhartha Jana (Hillsboro, Oregon); Federico Ardanaz (Hillsboro, Oregon); Jonathan M. Eastep (Portland, Oregon); Yaxin Shui (San Diego, California); Keith Underwood (Powell, Tennessee) |
| ABSTRACT | Described herein are automated hierarchical feed-back driven control mechanisms and methods, including an apparatus comprising a first circuitry, a second circuitry, and a third circuitry. The first circuitry may be operable to receive a system operating characteristic guidance. The second circuitry may be operable to provide one or more manufacturing characteristics. The third circuitry may be operable to store one or more system operating characteristics based upon the system operating characteristic guidance and the one or more manufacturing characteristics. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369580 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3206 (20130101) Original (OR) Class G06F 1/3234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050876 | Balasubramaniyan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Vijay Balasubramaniyan (Atlanta, Georgia); Mustaque Ahamad (Atlanta, Georgia); Patrick Gerard Traynor (Decatur, Georgia); Michael Thomas Hunter (Atlanta, Georgia); Aamir Poonawalla (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Monday, December 30, 2019 |
| APPL NO | 16/730666 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0829 (20130101) H04L 65/1076 (20130101) Telephonic Communication H04M 1/68 (20130101) H04M 3/2281 (20130101) Original (OR) Class H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) H04W 12/63 (20210101) H04W 12/65 (20210101) H04W 24/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11047232 | Knight et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biota Technology, Inc. (Oakland, California) |
| ASSIGNEE(S) | Biota Technology, Inc (San Diego, California) |
| INVENTOR(S) | Rob Knight (San Diego, California); Ajay Kshatriya (Oakland, California); John Ely (Houston, Texas); James Prestidge, Jr. (Cypress, Texas); Paul Henshaw (Clayton, California); Chris Lauber (Boulder, Colorado); J. Gregory Caporaso (Flagstaff, Arizona); Dan Knights (St. Paul, Minnesota); Ryan Gill (Denver, Colorado); Joel Moxley (Highlands Ranch, Colorado) |
| ABSTRACT | There are provided methods, systems and processes for the utilization of microbial and related genetic information for use in the exploration, determination, production and recovery of natural resources, including energy sources, and the monitoring, control and analysis of processes and activities. |
| FILED | Tuesday, December 30, 2014 |
| APPL NO | 14/586865 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/62 (20130101) C09K 8/582 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6874 (20130101) C12Q 1/6888 (20130101) C12Q 2600/156 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 21/065 (20130101) E21B 43/00 (20130101) E21B 43/26 (20130101) E21B 43/267 (20130101) E21B 47/11 (20200501) E21B 49/00 (20130101) E21B 49/003 (20130101) E21B 49/08 (20130101) Original (OR) Class E21B 49/086 (20130101) E21B 49/0875 (20200501) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 9/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 20/00 (20190201) G16B 40/00 (20190201) G16B 45/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11047693 | Schaefer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A system provides feedback to a user to guide the user to point a part of the body at a target of interest. An angle sensor senses the angle in which the part of the user's body is pointing, such as the head or the hand. The system computes the angle to a target and compares to the angle in which the part of the user's body is pointing and the feedback indicates to the user how to point more closely to the direction of the target. Additional sensors allow the system to update the angle to the target as the position of the user changes. A walking sensor is disclosed to accurately measure the position of the user. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123028 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3415 (20130101) Original (OR) Class G01C 21/3476 (20130101) G01C 21/3629 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/012 (20130101) G06F 3/013 (20130101) G06F 3/016 (20130101) G06F 3/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11050405 | Gorman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Jason J. Gorman (Silver Spring, Maryland); Vikrant J. Gokhale (Gaithersburg, Maryland) |
| ABSTRACT | A micromechanical vibrasolator isolates vibration of a micromechanical resonator and includes: phononic bandgap mirrors, monophones connected serially; phonophore arms in an alternating sequence of phonophore arm-monophone-phonophore arm; abutments in acoustic communication with the phononic bandgap mirrors; wherein the micromechanical resonator is interposed between the phononic bandgap mirrors with phononic bandgap mirror arranged in parallel on opposing sides of the micromechanical resonator arranged perpendicular to a direction of vibration of an in-plane vibrational mode of the micromechanical resonator. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 16/376533 |
| ART UNIT | 2832 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02433 (20130101) Original (OR) Class H03H 9/2452 (20130101) H03H 2009/0244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11047304 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Wendy Wenling Lin (Montgomery, Ohio); Shanmugam Murugappan (Mason, Ohio); Robert William Davidoff (Pittsburgh, Pennsylvania); Graham Frank Howarth (Middletown, Delaware); Andrew Michael Roach (Aberdeen, Maryland) |
| ABSTRACT | An acoustic core has a plurality of cell walls formed of an additive-manufacturing material and a resonant space defined by the plurality of cell walls. At least some of the resonant cells have a multitude of sound-attenuating protuberances formed of the additive-manufacturing material of the cell walls protruding into the resonant space with a random or semi-random orientation and/or size. The sound-attenuating protuberances may be formed by orienting an additive-manufacturing tool with respect to a toolpath to form a contour of a workpart, in which the toolpath includes a plurality of overlapping toolpath passes configured so as to intentionally introduce an amount of additive-manufacturing material to the workpart that exceeds a domain occupied by the contour. As the amount of additive-manufacturing material intentionally introduced exceeds the domain occupied by the contour, a portion of the additive-manufacturing material may incidentally form the plurality of sound-attenuating protuberances. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058171 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/10 (20210101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/008 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/10 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0002 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7504 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/045 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2230/31 (20130101) F05D 2230/50 (20130101) F05D 2240/14 (20130101) F05D 2260/96 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49323 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
MITRE Corporation (MITRE)
| US 11051030 | Taylor, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Robert M. Taylor, Jr. (New Market, Maryland); Jeffrey P. Woodard (McLean, Virginia) |
| ABSTRACT | A system and method for implementing a distributed source coding quantization scheme is provided. In one example, two independent but statistically correlated data sources can be asymmetrically compressed so that one source is compressed at a higher ratio than the other. The resulting signals are transmitted and decoded by a receiver. The highly compressed source can utilize the non-highly compressed source as side information so as to minimize the compression loss associated with the higher compression ratio. A conditional codebook can be created that not only depends on the highly compressed quantizer, but also depends on the quantized symbol received from the non-highly compressed data source. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734885 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 19/13 (20141101) H04N 19/94 (20141101) H04N 19/105 (20141101) H04N 19/124 (20141101) H04N 19/132 (20141101) H04N 19/157 (20141101) H04N 19/176 (20141101) Original (OR) Class H04N 19/179 (20141101) H04N 19/463 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11047906 | Erington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| ASSIGNEE(S) | DCG Systems, Inc. (Fremont, California); NXP USA, Inc. (Austin, Texas) |
| INVENTOR(S) | Kent Erington (Austin, Texas); Daniel J. Bodoh (Austin, Texas); Keith Serrels (Fremont, California); Theodore Lundquist (Milpitas, California) |
| ABSTRACT | Method to extract timing diagrams from synchronized single- or two-photon pulsed LADA by spatially positioning the incident laser beam on circuit feature of interest, temporally scanning the arrival time of the laser pulse with respect to the tester clock or the loop length trigger signal, then recording the magnitude and sign of the resulting fail rate signature per laser pulse arrival time. A Single-Photon Laser-Assisted Device Alteration apparatus applies picosecond laser pulses of wavelength having photon energy equal to or greater than the silicon band-gap. A Two-Photon Laser-Assisted Device Alteration apparatus applies femtosecond laser pulses of wavelength having photon energy equal to or greater than half the silicon band-gap at the area of interest. The laser pulses are synchronized with test vectors so that pass/fail ratios can be altered using either the single-photon or the two-photon absorption effect. A sequence of synthetic images with error data illustrates timing sensitive locations. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/259903 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/311 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11046030 | Barsoum |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roshdy George S. Barsoum (McLean, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roshdy George S. Barsoum (McLean, Virginia) |
| ABSTRACT | Marine vessels, including combatant (naval) vessels are produced inexpensively without requiring the use of as many skilled personnel as is conventional. The vessel produced has a high strength metal truss structure (both above and below the water line) capable of carrying major hull loads. A number of curved or doubly curved composite (e. g. GRP) panels produced by vacuum assisted resin transfer molding are fastened by bolts, marine adhesives, and/or rivets to the below water line portions of the truss structure where necessary to handle slamming loads and to reduce water resistance and wake. Substantially flat composite pultruded panels are fastened to the truss structure both above the water line, and below the water line where the resistance to slamming loads and reduction of water resistance and wake are not critical. Necessary equipment is installed within the open truss volume before the above-water-line panels are fully installed. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/501149 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/20 (20130101) B29C 51/261 (20130101) B29C 70/521 (20130101) B29C 70/526 (20130101) Original (OR) Class Ships or Other Waterborne Vessels; Equipment for Shipping B63B 5/24 (20130101) B63B 73/00 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050505 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Dynamics Mission Systems, Inc. (Fairfax, Virginia) |
| ASSIGNEE(S) | General Dynamics Mission Systems, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Nathaniel Jones (Florham Park, New Jersey); Stephanie Novak (Florham Park, New Jersey); Edward Rowe (Florham Park, New Jersey) |
| ABSTRACT | An optical communication system is configured to transmit and receive at least four multiplexed, differently-polarized, optically-transmitted signals. Each signal is associated with a predefined state of polarization. An optical transmitter is configured to transmit multiplexed, differently polarized, optically transmitted signals. An optical receiver is configured to receive the optically transmitted signals. The system includes a multi-polarization analyzer circuit configured to obtain an analyzed signal for each of the polarized signals in Stokes space. The analyzer circuit is configured to determine if the multiplexed signal has been transformed by extreme polarization-dependent loss (PDL), the receiver correcting for the extreme polarization-dependent loss. |
| FILED | Friday, February 14, 2020 |
| APPL NO | 16/791249 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6223 (20130101) Transmission H04B 10/61 (20130101) H04B 10/2507 (20130101) Multiplex Communication H04J 14/06 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11050604 | Robinson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland) |
| ABSTRACT | A method includes selecting a block size, via a processor of a communications system, and identifying a set of constellation points of a constellation diagram, based on a received set of bits and the constellation diagram. The constellation diagram is associated with a modulation scheme. A set of symbol blocks, based on the set of constellation points, is generated. Each symbol block from the set of symbol blocks has a size equal to the block size and includes a subset of constellation points from the set of constellation points. A unitary braid division multiplexing (UBDM) transformation is applied to each symbol block from the set of symbol blocks to produce a set of complex numbers. The set of complex numbers is then sent via the processor. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 16/889324 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0041 (20130101) H04L 1/0071 (20130101) H04L 27/0008 (20130101) H04L 27/3405 (20130101) H04L 27/3488 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 29, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
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