FedInvent Patents
Patent Details for Tuesday, July 06, 2021
This page was updated on Saturday, July 17, 2021 at 02:05 AM GMT
Department of Health and Human Services (HHS)
| US 11051499 | Stevens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland) |
| ASSIGNEE(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland) |
| INVENTOR(S) | Sean Stevens (Del Mar, California); Andrew J. Murphy (Croton-on-Hudson, New York); Richard Flavell (Guilford, Connecticut); Elizabeth Eynon (New Haven, Connecticut); Jorge Galan (New Haven, Connecticut); Tim Willinger (Ultran, Sweden); Markus Manz (Zollikon, Switzerland); Anthony Rongvaux (New Haven, Connecticut); George D. Yancopoulos (Yorktown Heights, New York) |
| ABSTRACT | A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mII2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/II2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic stem cells (HSCs) that maintains a human immune cell (HIC) population derived from the HSCs and that is infectable by a human pathogen, e.g., S. typhi or M. tuberculosis is described. A mouse that models a human pathogen infection that is poorly modeled in mice is described, e.g., a mouse that models a human mycobacterial infection, wherein the mouse develops one or more granulomas comprising human immune cells. A mouse that comprises a human hematopoietic malignancy that originates from an early human hematopoietic cells is described, e.g., a myeloid leukemia or a myeloproliferative neoplasia. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/352674 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0275 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) A01K 2267/0331 (20130101) A01K 2267/0337 (20130101) A01K 2267/0381 (20130101) A01K 2267/0387 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) Peptides C07K 14/524 (20130101) C07K 14/535 (20130101) C07K 14/5403 (20130101) C07K 14/7155 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051711 | Lattanzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Riccardo Lattanzi (New York, New York); Daniel K. Sodickson (New York, New York); José E. Cruz Serralles (Cambridge, Massachusetts); Athanasios Polymeridis (Moscow, Russian Federation); Luca Daniel (Cambridge, Massachusetts); Jacob K. White (Cambridge, Massachusetts) |
| ABSTRACT | A plurality of stimulations is transmitted to tissue or other material using one or more transmitters. The plurality of signals associated with the excited tissue and the transmitted stimulations are measured. The measured signals are processed to generate field-related quantities, such as B1+ and/or MR signal maps. Field-related quantities are generated also from simulation, by calculating the one or more incident fields from a simulator model of the one or more transmitters and assuming a given distribution of electrical properties in the tissue or other material. Field-related quantities generated from simulation and experimental procedures are compared to each other. The assumed electrical properties distribution is updated and the procedure is repeated iteratively until the difference between simulated and experimental field-related quantities is smaller than a threshold. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/494384 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00011 (20130101) A61B 5/0004 (20130101) A61B 5/0013 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 2576/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/48 (20130101) G01R 33/56 (20130101) G01R 33/246 (20130101) G01R 33/4616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051749 | Schalk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Health Research, Inc. (Menands, New York); Albany Medical College (Albany, New York) |
| ASSIGNEE(S) | Health Research, Inc. (Menands, New York); Albany Medical College (Albany, New York) |
| INVENTOR(S) | Gerwin Schalk (Glenmont, New York); Anthony L. Ritaccio (Voorheesville, New York); Adriana De Pesters (Coppet, Switzerland); AmiLyn Taplin (Albany, New York) |
| ABSTRACT | Provided is a method for mapping a neural area involved in speech processing, including applying a plurality of recording electrodes to a surface of a cortex of a human subject, presenting a plurality of auditory stimuli to the subject wherein some of the plurality of stimuli are speech sounds and others of the plurality of auditory stimuli are non-speech sounds, recording brain activity during the presenting of the plurality of auditory stimuli, and identifying one or more brain areas wherein activity changes more after presentation of speech sounds than it does after presentation of non-speech sounds, wherein the human subject does not speak during the presenting and the recording. Also provided is a method for mapping a neural area involved in speech production wherein the human subject does not speak during presenting speech stimuli and recording neural activity. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/570927 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/38 (20210101) Original (OR) Class A61B 5/4064 (20130101) A61B 5/4094 (20130101) A61B 2505/05 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/32 (20130101) A61N 1/0531 (20130101) A61N 1/36082 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051772 | Harrison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Daniel David Harrison (Delanson, New York); Ge Wang (Loudonville, New York) |
| ABSTRACT | Systems and method for performing X-ray computed tomography (CT) that can improve spectral separation and decrease motion artifacts without increasing radiation dose are provided. The systems and method can be used with either a kVp-switching source or a single-kVp source. When used with a kVp-switching source, an absorption grating and a filter grating can be disposed between the X-ray source and the sample to be imaged. Relative motion of the filter and absorption gratings can by synchronized to the kVp switching frequency of the X-ray source. When used with a single-kVp source, a combination of absorption and filter gratings can be used and can be driven in an oscillation movement that is optimized for a single-kVp X-ray source. With a single-kVp source, the absorption grating can also be omitted and the filter grating can remain stationary. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294438 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/482 (20130101) A61B 6/4007 (20130101) A61B 6/4035 (20130101) Original (OR) Class A61B 6/4085 (20130101) A61B 6/5258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051814 | Roundy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Neil Roundy (Portland, Oregon); Rachel Dreilinger (Lake Oswego, Oregon) |
| ABSTRACT | Surgical clips and surgical applicators used in performing rapid tissue closure in either minimally invasive surgeries or traditional open procedures are provided. In one example approach, a surgical clip comprises opposing sides extending from a top portion and terminating at tips positioned below the top portion. The resting position of the clip is its closed position, and in the closed position, the tips are set at a first distance apart. Each side has a cut-out (or hole or aperture) opposite one another. Each cut-out is fully surrounded by the side and does not extend to the top or tips. Each cut-out is configured to engage an inwardly turned hook at the end of a clip array or clip applicator such that the sides bend outwardly away from each other when pressure is applied on the top portion of the clip, thereby placing the clip in an open position. |
| FILED | Monday, September 15, 2014 |
| APPL NO | 14/486649 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/083 (20130101) Original (OR) Class A61B 17/128 (20130101) A61B 17/0293 (20130101) A61B 17/0682 (20130101) A61B 17/1227 (20130101) A61B 17/1285 (20130101) A61B 17/3421 (20130101) A61B 2017/0641 (20130101) A61B 2017/0645 (20130101) A61B 2017/00902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051871 | Nuccitelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pulse Biosciences, Inc. (Hayward, California) |
| ASSIGNEE(S) | Pulse Biosciences, Inc. (Hayward, California) |
| INVENTOR(S) | Richard Lee Nuccitelli (Millbrae, California); Pamela S. Nuccitelli (Millbrae, California); Joanne Lum (San Francisco, California); Kaying Lui (Millbrae, California); Brian G. Athos (San Francisco, California); Mark P. Kreis (San Francisco, California); Zachary R. Mallon (San Francisco, California); Jon Berridge (Oakland, California) |
| ABSTRACT | Nanosecond pulsed electric field (nsPEF) treatments of a tumor are adjusted based on a size and type of the tumor to stimulate an immune response against the tumor and other tumors in the subject. Calreticulin expression on tumor cells can be detected to confirm treatment. An immune response biomarker can be measured, and further nsPEF treatments can be performed if needed to stimulate or further stimulate the immune response. Cancers that have metastasized may be treated by directly treating a tumor that is most accessible. The treatment can be combined with CD47-blocking antibodies, doxorubicin, CTLA-4-blocking antibodies, and/or PD-1-blocking antibodies. Electrical characteristics of nsPEF treatments can be based on the size, type, and/or strength of tumors and/or a quantity of tumors in the subject. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909948 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) Original (OR) Class A61B 18/1477 (20130101) A61B 2018/0016 (20130101) A61B 2018/143 (20130101) A61B 2018/00452 (20130101) A61B 2018/00613 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 35/13 (20130101) A61K 39/395 (20130101) A61K 39/395 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/00 (20130101) A61N 1/00 (20130101) A61N 1/05 (20130101) A61N 1/32 (20130101) A61N 1/36 (20130101) A61N 1/40 (20130101) A61N 1/327 (20130101) A61N 1/328 (20130101) A61N 1/0412 (20130101) A61N 1/0424 (20130101) A61N 1/0502 (20130101) A61N 1/37229 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2818 (20130101) C07K 2317/76 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 13/00 (20130101) C12N 15/87 (20130101) C12N 2501/599 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051902 | Kruecker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jochen Kruecker (Andover, Massachusetts); Pingkun Yan (Gaithersburg, Maryland); Amir Mohammad Tahmasebi Maraghoosh (Arlington, Massachusetts); Peter A Pinto (Bethesda, Maryland); Bradford Johns Wood (Potomac, Maryland) |
| ASSIGNEE(S) | KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); THE UNITED STATES OF AMERICA, as represented by the SECRETARY, DEPT OF HEALTH AND HUMAN SERVICES (Bethesda, Massachusetts) |
| INVENTOR(S) | Jochen Kruecker (Andover, Massachusetts); Pingkun Yan (Gaithersburg, Maryland); Amir Mohammad Tahmasebi Maraghoosh (Arlington, Massachusetts); Peter A Pinto (Bethesda, Maryland); Bradford Johns Wood (Potomac, Maryland) |
| ABSTRACT | A system for planning and performing a repeat interventional procedure includes a registration device (116) and an image generation device (120) which map current targets in a reference image (104) for a first interventional procedure to at least one guidance image (112) acquired from a different imaging modality. Biopsy locations are recorded to the guidance images during the first interventional procedure and the biopsy locations are mapped to the reference image to provide a planning image for use in a subsequent interventional procedure on the patient. In a subsequent interventional procedure, the prior planning image (124) may be registered to a current reference image (126) and the prior biopsy locations and prior and current targets are mapped to a guidance image acquired from a different imaging modality. Biopsy locations are then mapped to the guidance image (115) and mapped back to the current reference image. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/754602 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/085 (20130101) A61B 8/463 (20130101) A61B 8/0841 (20130101) A61B 8/5261 (20130101) A61B 10/0241 (20130101) A61B 34/10 (20160201) A61B 90/36 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2090/374 (20160201) Image Data Processing or Generation, in General G06T 7/0014 (20130101) G06T 11/003 (20130101) G06T 2207/10088 (20130101) G06T 2207/10132 (20130101) G06T 2207/30081 (20130101) G06T 2207/30204 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 20/40 (20180101) G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 40/63 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 70/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051975 | Tai |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g. 37° C. in a human), such as from 43° C. to 54° C. for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15° C. to 30° C. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/780748 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/02 (20130101) A61F 7/007 (20130101) A61F 7/12 (20130101) Original (OR) Class A61F 2007/0054 (20130101) A61F 2007/0071 (20130101) A61F 2007/0075 (20130101) A61F 2007/0086 (20130101) A61F 2007/0088 (20130101) A61F 2007/0093 (20130101) A61F 2007/0096 (20130101) A61F 2007/126 (20130101) A61F 2007/0285 (20130101) A61F 2007/0295 (20130101) A61F 2007/0296 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 19/00 (20130101) A61M 2205/3368 (20130101) A61M 2205/3523 (20130101) A61M 2205/3606 (20130101) A61M 2205/3653 (20130101) A61M 2205/3673 (20130101) A61M 2205/3686 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/025 (20130101) A61N 5/0625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052044 | Brea Fernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roberto Javier Brea Fernandez (San Diego, California); Christian Cole (Del Mar, California); Neal K. Devaraj (La Jolla, California); Brent Lyda (San Diego, California); Roger Sunahara (San Diego, California) |
| ABSTRACT | Described herein, inter alia, are compositions and methods useful for the reconstitution of membrane proteins. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 16/489783 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1277 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/106 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/14 (20130101) Peptides C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052045 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); Junqing Cui (West Roxbury, Massachusetts); Rud Karly Lucien (Lynn, Massachusetts); Ryan Carney (Hudson, New Hampshire); Jihae Sohn (Brighton, Massachusetts); Michelle Arya (Medford, Massachusetts) |
| ABSTRACT | A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383201 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/1617 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 9/1688 (20130101) A61K 35/16 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/06 (20130101) B01J 2219/00177 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 51/30 (20130101) B65D 81/266 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/04 (20130101) F26B 3/06 (20130101) F26B 3/12 (20130101) F26B 5/04 (20130101) F26B 5/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052057 | Rubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MESHABERASE, LLC (Potomac, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | MESHABERASE, LLC (Potomac, Maryland); The United States of America, as Represented by the Secretary, Dept of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Benjamin Rubin (Potomac, Maryland); Raj Puri (Bethesda, Maryland); Bharat Joshi (Bethesda, Maryland) |
| ABSTRACT | The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594827 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/28 (20130101) A61K 9/0053 (20130101) A61K 9/4891 (20130101) A61K 31/145 (20130101) Original (OR) Class A61K 31/145 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052070 | Wrobel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BIOHAVEN THERAPEUTICS LTD. (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689150 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052080 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Florence Fevrier Wagner (Ashland, Massachusetts); Jennifer Q. Pan (Acton, Massachusetts); Sivaraman Dandapani (Wakefield, Massachusetts); Andrew Germain (Somerville, Massachusetts); Edward Holson (Newton, Massachusetts); Benito Munoz (Newtonville, Massachusetts); Partha P. Nag (Somerville, Massachusetts); Michael C. Lewis (Dedham, Massachusetts); Stephen J. Haggarty (Gloucester, Massachusetts); Joshua A. Bishop (Southborough, Massachusetts); Kimberly Stegmaier (Jamaica Plain, Massachusetts); Michel Weiwer (Cambridge, Massachusetts); Versha Banerji (Winnipeg, Canada) |
| ABSTRACT | The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/198589 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 31/4747 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 471/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052081 | Govindan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); David M. Goldenberg (Delray Beach, Florida) |
| ABSTRACT | The present invention relates to therapeutic ADCs comprising SN-38 attached to an anti-Trop-2 antibody or antigen-binding antibody fragment. The ADC may be administered at a dosage of between 4 mg/kg and 18 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg, most preferably 8 to 10 mg/kg. When administered at specified dosages and schedules, the ADC can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Preferably, the ADC is administered in combination with one or more other therapeutic agents, such as a PARP inhibitor, a microtubule inhibitor, a Bruton kinase inhibitor or a PI3K inhibitor. Most preferably, the ADC is of use for treating a Trop-2 expressing cancer, such as metastatic urothelial cancer. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524913 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/52 (20130101) A61K 31/52 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/502 (20130101) A61K 31/502 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/303 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3061 (20130101) C07K 16/3092 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052089 | Cheresh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | David A. Cheresh (La Jolla, California); Maricel Gozo (La Jolla, California); Mayra Yebra (La Jolla, California); Laetitia Seguin (La Jolla, California) |
| ABSTRACT | In alternative embodiments, provided are compositions and methods for treating, enhancing the drug sensitivity of, and preventing the formation of cancer stems cells, including preventing or slowing the development or generation of a beta-3 (β3)-expressing, or integrin β3 (ITG-B3)-expressing cancer or tumor cells. In alternative embodiments, provided are methods using histone acetyl transferase inhibitors and/or histone methyl transferase inhibitors to determine therapeutic values in cancer cells that induce an integrin β3 (ITGB3) polypeptide expression. In alternative embodiments, provided are kits, blister packages, lidded blisters or a blister card or packet, clamshells, trays or shrink wraps, comprising at least one compound, composition or formulation used to practice a method as provided herein, and at least one Growth Factor Inhibitor. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 15/537403 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 31/444 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052140 | Yee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cassian Yee (Houston, Texas); Yongqing Li (Shoreline, Washington); C. Siddiq Abdul-Alim (Kent, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cassian Yee (Houston, Texas); Yongqing Li (Shoreline, Washington); C. Siddiq Abdul-Alim (Kent, Washington) |
| ABSTRACT | What is described is a method of treatment of a patient with a tumor, comprising administering a cell responsive to a peptide comprising a tumor epitope, wherein the tumor epitope comprises an amino acid substitution in a tumor antigen. The tumor antigen is preferably selected from the group consisting of NYESO-I157-165, NYESO-II157-170, or MART-126-35, preferably SEQ ID NOS: 1-351, 361-376, and 392-401. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450302 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/001188 (20180801) A61K 39/001191 (20180801) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/515 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/4748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052147 | Sediq et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Janssen Vaccines and Prevention B.V. (Leiden, Netherlands); Bavarian Nordic A/S (Kvistgaard, Denmark) |
| ASSIGNEE(S) | JANSSEN VACCINES and PREVENTION B.V. (, None) |
| INVENTOR(S) | Ahmad Shakeb Sediq (Basel, Switzerland); Wouter Frank Tonnis (Berlin, Germany); Martinus Anne Hobbe Capelle (Sassenheim, Netherlands) |
| ABSTRACT | Described herein are compositions and pharmaceutical compositions including poxviruses, in particular vaccinia virus such as modified vaccinia Ankara (MVA) virus, a sulfate salt at a concentration between about 5 mM and 300 mM and a buffer, wherein the composition has a pH of between about 6.0 and 8.5. Also described are methods for stabilizing a poxvirus composition by preparing said viral formulation. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/612561 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/285 (20130101) Original (OR) Class A61K 47/20 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052149 | Ting et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Jenny P.-Y. Ting (Chapel Hill, North Carolina); Robert Junkins (Durham, North Carolina); Brandon Johnson (Durham, North Carolina); Kristy Ainslie (Chapel Hill, North Carolina); Eric Bachelder (Chapel Hill, North Carolina); Matthew Gallovic (Carrboro, North Carolina); Michael Collier (Durham, North Carolina); Ning Cheng (Cary, North Carolina) |
| ABSTRACT | The present invention provides a composition comprising a) a polyacetal polymer, a polyester polymer and/or a biodegradable polymer; b) a cyclic dinucleotide; and c) an antigen and/or an antibody, as well as methods of using same. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 16/334153 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1272 (20130101) A61K 9/1647 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/7084 (20130101) A61K 31/7084 (20130101) A61K 39/0008 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 2039/5154 (20130101) A61K 2039/55505 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) A61K 2039/55572 (20130101) A61K 2039/55577 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 31/16 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052151 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Elaine Hsiao (Rowland Heights, California); Sarkis K. Mazmanian (Porter Ranch, California); Paul H. Patterson (Altadena, California); Sara McBride (Pasadena, California) |
| ABSTRACT | Disclosed herein are compositions, systems, and methods for diagnosing and treatment of subjects suffering from anxiety, autism spectrum disorder (ASD), or a pathological condition with one or more of the symptoms of ASD. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/193724 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/7076 (20130101) G01N 2800/7085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052156 | Goldenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | David M. Goldenberg (Delray Beach, Florida); Serengulam V. Govindan (Summit, New Jersey) |
| ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/684188 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7088 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 41/0038 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6851 (20170801) Original (OR) Class A61K 47/6855 (20170801) A61K 47/6859 (20170801) A61K 47/6863 (20170801) A61K 47/6889 (20170801) A61K 51/1045 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) A61N 2005/1021 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3076 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052161 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Matthew S. Freeman (Cincinnati, Ohio); Bastiaan Driehuys (Chapel Hill, North Carolina) |
| ABSTRACT | Systems, methods and related devices used to produce and collect polarized noble gas to inhibit, suppress, detect or filter alkali metal nanoclusters to preserve or increase a polarization level thereof. The systems can include a pre-sat chamber that has an Area Ratio between 20 and 500. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113607 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/18 (20130101) A61K 49/106 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 23/00 (20130101) C01B 23/0036 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052163 | Lanza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory M. Lanza (St. Louis, Missouri); Samuel I. Achilefu (St. Louis, Missouri); Grace Hufang Cui (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Gregory M. Lanza (St. Louis, Missouri); Samuel I. Achilefu (St. Louis, Missouri); Grace Hufang Cui (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides peptide constructs for diagnostic imaging and therapeutic applications, using pegylated peptides which exhibit specific binding for a target molecule of interest, such as a biomarker of a disease or disorder. |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/711780 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) A61K 49/0056 (20130101) A61K 49/085 (20130101) A61K 49/124 (20130101) A61K 51/065 (20130101) A61K 51/088 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052177 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hyun-Su Lee (Wayne, Pennsylvania); David M. Eckmann (Wynnewood, Pennsylvania); Russell Composto (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention provides compositions comprising a plurality of polymer layers for preventing or inhibiting microbial infections. Specifically, the invention provides a combination of a cationic polymer layer that resists adhesion of a microbe to its surface and an anionic polymer layer that releases a cationic anti-microbial agent in response to a change in pH or electrostatic balance. |
| FILED | Monday, September 08, 2014 |
| APPL NO | 14/479536 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/46 (20130101) A61L 15/225 (20130101) A61L 15/225 (20130101) A61L 15/225 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) Original (OR) Class A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/404 (20130101) A61L 2300/406 (20130101) A61L 2420/02 (20130101) A61L 2420/08 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 33/02 (20130101) C08L 33/02 (20130101) C08L 33/02 (20130101) C08L 33/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052368 | Weitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Vilnius University (Vilnius, Lithuania) |
| ASSIGNEE(S) | Vilnius University (Vilnius, Lithuania); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Allon Moshe Klein (Boston, Massachusetts); Ilke Akartuna (Cambridge, Massachusetts); Linas Mazutis (Vilnius, Lithuania); Marc W. Kirschner (Newton, Massachusetts) |
| ABSTRACT | The present invention generally relates to microfluidics and labeled nucleic acids. For example, certain aspects are generally directed to systems and methods for labeling nucleic acids within microfluidic droplets. In one set of embodiments, the nucleic acids may include “barcodes” or unique sequences that can be used to distinguish nucleic acids in a droplet from those in another droplet, for instance, even after the nucleic acids are pooled together. In some cases, the unique sequences may be incorporated into individual droplets using particles and attached to nucleic acids contained within the droplets (for example, released from lysed cells). In some cases, the barcodes may be used to distinguish tens, hundreds, or even thousands of nucleic acids, e.g., arising from different cells or other sources. |
| FILED | Tuesday, May 29, 2018 |
| APPL NO | 15/991600 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0062 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00585 (20130101) B01J 2219/00722 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/0652 (20130101) B01L 2300/021 (20130101) B01L 2300/0663 (20130101) B01L 2300/0858 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053209 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 16/611329 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053236 | Sucheck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Steven Sucheck (Toledo, Ohio); Sandeep Thanna (Toledo, Ohio); Donald Ronning (Toledo, Ohio); Alexander Landgraf (Toledo, Ohio) |
| ABSTRACT | Compounds, compositions, and methods for the treatment of infections, inflammation, cancers, tinnitus, Meniere's disease, hearing loss, or bipolar disorder, or for providing cytoprotection against Clostridium difficile toxins, are disclosed. |
| FILED | Wednesday, June 21, 2017 |
| APPL NO | 16/312024 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/00 (20180101) A61P 27/16 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 31/06 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 293/10 (20130101) C07D 421/04 (20130101) Original (OR) Class C07D 421/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053252 | Gangjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania); Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania); Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania); Larry H. Matherly (Novi, Michigan) |
| ABSTRACT | Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I: These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801943 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 239/70 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053285 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
| ABSTRACT | The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020543 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/6075 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053289 | Truong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | David M. Truong (New York, New York); Jef D. Boeke (New York, New York) |
| ABSTRACT | Yeast having modified chromosomes are provided. The chromosomes are modified such that at least one of yeast histones H3, H4, H2A or H2B are fully or partially replaced by their human histone counterparts H3, H4, H2A or H2B, respectively. Histone amino acid substitutions are included. Cell fusions with the yeast having the modified chromosomes and non-yeast cells are provided. Methods for screening test agents using the yeast are also provided. Yeast with a mutated yeast DAD1 gene, the mutated DAD1 gene encoding an E50D mutation in yeast DAD1 protein, are provided, and provide a useful genetic background for making the yeast with partially or fully replaced histone(s). |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042417 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/395 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053290 | Ashkar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); The United States Government as Represented by the Department of Veterans Affair (Washington D.C., District of Columbia) |
| INVENTOR(S) | Tarek Maurice Ashkar (Zionsville, Indiana); Radmila Micanovic (Indianapolis, Indiana) |
| ABSTRACT | Embodiments of the present disclosure provide polypeptides, related materials and compositions, and methods for their use. In certain embodiments, the present disclosure provides a monomeric Tamm-Horsfall Protein polypeptide, or a biologically active truncation thereof. Other embodiments provide polynucleotides encoding a polypeptide described herein, nucleic acid expression vectors including the polynucleotides, and recombinant host cells including the expression vector. Yet other embodiments provide pharmaceutical compositions including a polypeptide described herein. Also provided are methods for treating a renal disease, disorder, or condition in a subject and/or modulating an immune response in a subject. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/771036 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 35/22 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/435 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053291 | Ildefonso et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Cristhian J. Ildefonso (Gainesville, Florida); Alfred S. Lewin (Gainesville, Florida); Qiuhong Li (Gainesville, Florida) |
| ABSTRACT | The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or inflammation, including ocular inflammation. In some embodiments, the methods comprise administering an expression vector that delivers a secretable and cell penetrating Nrf2 to a subject in need thereof. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 15/120318 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/1709 (20130101) A61K 48/0075 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/10 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053292 | Galipeau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jacques Galipeau (Atlanta, Georgia); Jiusheng Deng (Snellville, Georgia) |
| ABSTRACT | In certain embodiments, this disclosure relates to conjugates comprising a polypeptide of GM-CSF and a polypeptide IL-4. Typically, the GM-CSF and IL-4 are connected by a linker, e.g., polypeptide. In certain embodiments, the disclosure relates to isolated nucleic acids encoding these polypeptide conjugates, vectors comprising nucleic acid encoding polypeptide conjugates, and protein expression systems comprising these vectors such as infectious viral particles and host cells comprising such nucleic acids. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149372 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 38/00 (20130101) A61K 38/193 (20130101) A61K 38/2026 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 47/42 (20130101) A61K 2039/5152 (20130101) A61K 2039/5156 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) Peptides C07K 14/535 (20130101) C07K 14/5406 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 15/09 (20130101) C12N 15/1024 (20130101) C12N 15/1027 (20130101) C12N 15/1062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053293 | Krupnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Sasha Krupnick (St. Louis, Missouri); Daved Henry Fremont (St. Louis, Missouri); Eric Reed Lazear (St. Louis, Missouri) |
| ABSTRACT | The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 16/075069 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6849 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/52 (20130101) C07K 14/55 (20130101) Original (OR) Class C07K 14/545 (20130101) C07K 14/5418 (20130101) C07K 14/5443 (20130101) C07K 14/70596 (20130101) C07K 16/2851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053297 | Hedrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | La Jolla Institute for Allergy and Immunology (La Jolla, California) |
| ASSIGNEE(S) | La Jolla Institute for Allergy and Immunology (La Jolla, California) |
| INVENTOR(S) | Catherine C. Hedrick (La Jolla, California); Richard Hanna (San Diego, California) |
| ABSTRACT | Disclosed herein are methods of increasing numbers of monocytes to a tumor or cancer metastasis site in a subject. Non-limiting embodiments include administering or using a Nur77 polypeptide or subsequence thereof; a Nur77 agonist; a CX3CR1 agonist; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+ GR1− (Ly6C−)) monocytes; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes contacted with a Nur77 agonist or contacted with a CX3CR1 agonist. Also disclosed herein are methods of increasing, stimulating, activating or promoting monocyte migration to or mobilization against a tumor or cancer metastasis in a subject. Non-limiting embodiments include administering a Nur77 polypeptide or subsequence thereof; a Nur77 agonist; a CX3CR1 agonist; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes; or CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes contacted with a Nur77 agonist or contacted with a CX3CR1 agonist. |
| FILED | Thursday, October 27, 2016 |
| APPL NO | 15/772388 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 35/15 (20130101) A61K 38/195 (20130101) A61K 38/1783 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/6849 (20170801) A61K 2039/545 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/70567 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 16/2857 (20130101) C07K 2317/20 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053301 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Gerhard Wagner (Chestnut Hill, Massachusetts); Mahmoud Nasr (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions relating to nanodiscs, e.g., phospholipid bilayers with a proteinaceous belt or border. Further provided herein are loopable membrane scaffold proteins, e.g., for forming nanodiscs. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 16/317924 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 2039/55555 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 1/045 (20130101) C07K 1/047 (20130101) C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/775 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101) C12N 9/80 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053310 | Wadehra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Madhuri Wadehra (Fontana, California); Jonathan Braun (Tarzana, California) |
| ABSTRACT | Provided herein are novel anti-EMP2 antibodies useful for the treatment and diagnosis of cancers that express or overexpress EMP2. In one aspect, provided herein is an isolated antibody that binds to Epithelial Membrane Protein 2 (EMP2), that includes heavy chain variable region and a light chain variable region. The heavy chain variable region includes three heavy chain complementary determining regions (HCDRs) and the light chain variable region includes three light chain variable regions (LCDRs). In some embodiments, the sequence of HCDR1 is SEQ ID NO: 11, the sequence of HCDR2 is SEQ ID NO: 12, the sequence of HCDR3 is SEQ ID NO: 13, the sequence of LCDR1 is SEQ ID NO:14, the sequence of LCDR2 is SEQ ID NO: 15, and the sequence of LCDR3 is SEQ ID NO: 16. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/780334 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/22 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/2863 (20130101) C07K 2317/40 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/577 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053314 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); Sukhbir Kaur (Bethesda, Maryland); Chengyu Liu (Boyds, Maryland) |
| ABSTRACT | Described herein is the discovery that cancer stem cells (CSCs) can be induced to differentiate by altering CD47 signaling. Provided herein are methods and compositions for inducing differentiation of cancer stem cells, for instance irreversible differentiation, including methods of treating subjects with cancer such as breast cancer, colon cancer, lung cancer, ovarian cancer, or melanoma, and including metastatic as well as primary cancer. Also provided are methods for treating subjects with triple negative breast cancers involving forcing differentiation of bCSCs of the subjects through targeting of CD47. |
| FILED | Friday, October 09, 2015 |
| APPL NO | 15/517345 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 39/00 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 16/3015 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053322 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Juntao Luo (Jamesville, New York); Wei He (Davis, California); Kit S. Lam (Davis, California); Paul Henderson (Dublin, California); Matthew A. Coleman (Oakland, California) |
| ABSTRACT | The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a polyethylene glycol) polymer; each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499855 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/775 (20130101) C07K 17/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053468 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Hongjun Song (Clarksville, Maryland); Guoli Ming (Clarksville, Maryland); Mingxi Max Song (Clarksville, Maryland); Christopher Hadiono (Armonk, New York); William Jeang (Houston, Texas); Ha Nam Nguyen (Baltimore, Maryland); Xuyu Qian (Baltimore, Maryland) |
| ABSTRACT | A method of cell culture and a method of generating organoids is provided. The methods utilize a cell culture system which includes a multiwell culture plate having shafts for mixing culture media within wells of the culture plate. The multiwell culture plate includes a base substrate having a plurality of culture wells, and a shaft operably associated with each culture well, each shaft being configured to mix media present in each culture well and having a gear adapted to operably associate with a gear on a shaft associated with an adjacent culture well. The system further includes a motor having a drive shaft in operable communication with the shaft gears of the multiwell culture plate. The system can be widely used as a standard platform to generate stem cell-derived human organoids for any tissue and for high-throughput drug screenings, toxicity testing, and modeling normal human organ development and diseases. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804924 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 7/18 (20130101) B01F 7/00133 (20130101) B01F 7/00141 (20130101) B01F 13/1022 (20130101) B01F 15/00454 (20130101) B01F 2015/00623 (20130101) B01F 2215/0481 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) Original (OR) Class C12M 25/06 (20130101) C12M 27/02 (20130101) C12M 27/10 (20130101) C12M 41/36 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/5082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053475 | Bresnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Emery H. Bresnick (Middleton, Wisconsin); Xin Gao (Madison, Wisconsin); Kirby D. Johnson (Middleton, Wisconsin) |
| ABSTRACT | Described herein are methods of expanding a population of hematopoietic stem cells by contacting the population of hematopoietic stem cells with an effective amount of an inhibitor of G-protein coupled receptor 65 (GPR65) and providing a population of expanded, substantially undifferentiated hematopoietic stem cells. Exemplary GPR65 inhibitors include siRNAs and certain sphingolipids. Also described are populations of expanded hematopoietic stem cells produced by the methods, media and kits containing GPR65 inhibitors, and methods for administering an expanded population of hematopoietic stem cells to patients. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 16/749190 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2501/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053477 | Wells et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | James Macormack Wells (Cincinnati, Ohio); Kyle William McCracken (Cincinnati, Ohio) |
| ABSTRACT | Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/188597 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/16 (20130101) C12N 2501/113 (20130101) C12N 2501/115 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053481 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (Pasadena, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Tuesday, July 08, 2014 |
| APPL NO | 14/325815 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053491 | Brangwynne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Cliff Brangwynne (Hopewell, New Jersey); Jared Toettcher (Princeton, New Jersey); Yongdae Shin (Lawrenceville, New Jersey) |
| ABSTRACT | A protein construct including a gene encoding a light-sensitive protein fused to at least one of either a low complexity sequence, an intrinsically disordered protein region (IDR), or a repeating sequence of a linker and another gene encoding a light-sensitive protein. Among the many different possibilities contemplated, the protein construct may also advantageously include cleavage tags. This protein construct may be utilized for a variety of functions, including a method for protein purification, which requires introducing the protein construct into a living cell, and inducing the formation of clusters by irradiating the construct with light. The method may also advantageously include cleaving a target protein from an IDR, and separating the clusters via centrifuge. A kit for practicing in vivo aggregation or liquid-liquid phase separation is also included, the kit including the protein construct and a light source capable of producing a wavelength that the light-sensitive protein will respond to. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701399 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/32 (20130101) C07K 14/43595 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class C12N 13/00 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Enzymes C12Y 401/99003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053494 | Flanigan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Institute at Nationwide Children's Hospital (Columbus, Ohio); The University of Western Australia (Crawley, Australia) |
| ASSIGNEE(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio); THE UNIVERSITY OF WESTERN AUSTRALIA (Nedlands, Australia) |
| INVENTOR(S) | Kevin Flanigan (Columbus, Ohio); Nicolas Wein (Columbus, Ohio); Stephen Wilton (Perth, Australia) |
| ABSTRACT | The present invention relates to the delivery of oligomers for treating patients with a 5′ mutation in their DMD gene other than a DMD exon 2 duplication. The invention provides methods and materials for activating an internal ribosome entry site in exon 5 of the DMD gene resulting in translation of a functional truncated isoform of dystrophin. The methods and materials can be used for the treatment of muscular dystrophies arising from 5′ mutations in the DMD gene such as Duchenne Muscular Dystrophy or Becker Muscular Dystrophy. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 15/502702 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/58 (20130101) A61K 31/573 (20130101) A61K 31/712 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) C12N 2310/3513 (20130101) C12N 2310/3519 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) C12N 2330/51 (20130101) C12N 2750/14143 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053535 | Ramsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Michael Ramsey (Chapel Hill, North Carolina); Jean Pierre Alarie (Chapel Hill, North Carolina); Laurent Menard (Cary, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); Jean Pierre Alarie (Chapel Hill, North Carolina); Laurent Menard (Cary, North Carolina) |
| ABSTRACT | Devices, such as chips for DNA analysis, have at least one fluid transport nanochannel with at least one intersecting (e.g., transverse) sensing nanochannel that can be monitored for change in ionic current to determine characteristics or parameters of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like. |
| FILED | Friday, September 07, 2012 |
| APPL NO | 14/342032 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053550 | Moffitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard Moffitt (Chapel Hill, North Carolina); Jen Jen Yeh (Chapel Hill, North Carolina); Naim Ur Rashid (Chapel Hill, North Carolina) |
| ABSTRACT | Methods for generating a prognostic and/or subtype signature for a subject with pancreatic ductal adenocarcinoma (PDAC) are provided. In some embodiments, the methods include determining expression levels for one or more genes listed in Tables 2-5, 9, 10, or 11, and/or the DE-S and/or DE-T subset of genes in PDAC cells obtained from the subject, wherein the determining provides a prognostic and/or subtype signature for the subject. Also provided are methods for classifying a subject diagnosed with pancreatic ductal adenocarcinoma (PDAC) as having an activated stroma subtype or a normal stroma subtype of PDAC and/or a basal subtype or a classical subtype of PDAC; and methods for identifying a differential treatment strategy for a subject diagnosed with pancreatic ductal adenocarcinoma (PDAC). |
| FILED | Wednesday, October 14, 2015 |
| APPL NO | 15/518900 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) G01N 2800/52 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054413 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart Martin (Severna Park, Maryland); Christopher M. Jewell (Silver Spring, Maryland); James I. Andorko (Delran, New Jersey); Elisabeth Lily Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Stuart Martin (Severna Park, Maryland); Christopher M. Jewell (Silver Spring, Maryland); James I. Andorko (Delran, New Jersey); Elisabeth Lily Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ABSTRACT | The present invention provides a device for assaying living cells comprising a substrate, wherein the substrate comprises one or more tethering molecules which adhere to the substrate and are capable of interacting with cell membranes of the cells, wherein the cells maintain a free-floating, non-adherent character when bound to the one or more tethering molecules. |
| FILED | Wednesday, October 07, 2015 |
| APPL NO | 14/877864 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95 (20130101) G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2800/7028 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054422 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sheng-He Huang (Arcadia, California); Alec Chan (San Gabriel, California) |
| ASSIGNEE(S) | Sheng-He Huang (Arcadia, California); Alec Chan (San Gabriel, California) |
| INVENTOR(S) | Sheng-He Huang (Arcadia, California) |
| ABSTRACT | The invention provides the use of circulating astrocytes (cAstr) and the Major Facilitator Superfamily Domain containing Protein 2a (Mfsd2a) as biomarkers, and their combined use with other related circulating markers (cBMEC and EPC) in early detection and diagnosis of cerebrovascular diseases (CVD) or central nervous system (CNS) disorders. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431559 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 45/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class G01N 2333/70571 (20130101) G01N 2800/50 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054423 | Crowe, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Andrew I. Flyak (Nashville, Tennessee); Alexander Bukreyev (Galveston, Texas); Philipp Ilinykh (Galveston, Texas) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/790658 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/10 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/577 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055351 | Shyu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chi-Ren Shyu (Columbia, Missouri); Michael Phinney (Columbia, Missouri) |
| ABSTRACT | The present disclosure relates to a persistent data structure employed as a tree structure with a frequent pattern mining paradigm. The number of nodes in the tree structure scales linearly with respect to the number unique items within the itemsets associated with the nodes. With the disclosed pattern mining paradigm, compressed representations of maximal patterns may be mined with the goal of detecting a frequent maximal pattern covers in a top down approach. Thus, large patterns are detected before their subsets yielding a significant reduction in computation time. The persistent data structure is a dynamic data structure which may be updated to add or delete nodes or transactional information without the need for recreating the entire tree structure. Furthermore, the persistent data structure may be run by a computing system either locally or on a parallelized distributed computing architecture to increase operational performance. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955462 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) G06F 16/2246 (20190101) G06F 16/2379 (20190101) G06F 16/2465 (20190101) G06F 16/9027 (20190101) Original (OR) Class G06F 2216/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055565 | Boespflug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Erin L. Boespflug (Portland, Oregon); David Lahna (Portland, Oregon); Daniel Schwartz (Portland, Oregon); Lisa C Silbert (Portland, Oregon) |
| ABSTRACT | Disclosed herein are methods and systems for the identification and characterization of perivascular spaces in the cerebral vasculature using magnetic resonance imaging (MRI) data. The disclosed methods allow for automated and unbiased quantification of enlarged perivascular space (ePVS) in a subject, and thus can provide a substantial improvement over manual grading methods used in the art. An example method includes receiving an MRI dataset including voxels having intensity values, identifying a set of candidate voxels within the MRI dataset based on the intensity values; grouping the set of candidate voxels into a set of first clusters; filtering the set of first clusters to generate a set of second clusters; and filtering the set of second clusters based on a morphologic constraint, thereby identifying an enlarged perivascular space in the MRI dataset. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/556029 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/623 (20130101) Original (OR) Class G06K 9/4638 (20130101) G06K 9/4647 (20130101) G06K 9/6288 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/13 (20170101) G06T 7/62 (20170101) G06T 2207/10076 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/30016 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055844 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Xiangxue Wang (Cleveland Heights, Ohio); Cristian Barrera (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio) |
| ABSTRACT | Embodiments access a digitized image of tissue demonstrating non-small cell lung cancer (NSCLC), the tissue including a plurality of cellular nuclei; segment the plurality of cellular nuclei represented in the digitized image; extract a set of nuclear radiomic features from the plurality of segmented cellular nuclei; generate at least one nuclear cell graph (CG) based on the plurality of segmented nuclei; compute a set of CG features based on the nuclear CG; provide the set of nuclear radiomic features and the set of CG features to a machine learning classifier; receive, from the machine learning classifier, a probability that the tissue will respond to immunotherapy, based, at least in part, on the set of nuclear radiomic features and the set of CG features; generate a classification of the tissue as a responder or non-responder based on the probability; and display the classification. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/281324 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00147 (20130101) G06K 9/469 (20130101) G06K 9/6257 (20130101) G06K 9/6262 (20130101) G06K 9/6267 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 7/62 (20170101) G06T 2207/10056 (20130101) G06T 2207/20072 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056022 | Horowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPROUTEL, INC. (Providence, Rhode Island) |
| ASSIGNEE(S) | Sproutel, Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Aaron J. Horowitz (Providence, Rhode Island); Hannah Chung (Providence, Rhode Island); Joel B. Schwartz (Los Angeles, California); Brian Oley (Jamaica Plain, Massachusetts) |
| ABSTRACT | An interactive augmented reality system for simulating medical procedures for pediatric disease education includes a plush toy having one or more patches disposed on a body of the plush toy in one or more corresponding locations each associated with an area of the body of the plush toy that is comparable to an area of a human body. An interactive medical procedure simulation logic section operable within a mobile device causes a particular patch within a series of live images to be scanned, and initiates an interactive augmented reality experience to simulate a medical procedure for pediatric disease education. Comfort is provided to children struggling with a disease. Children learn how to manage their chronic illness by enabling them to practice their medical procedures and receive feedback related to correct and incorrect care. A low-cost disease education delivery mechanism is provided directly to children through game-play. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/984138 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Toys, e.g Tops, Dolls, Hoops or Building Blocks A63H 3/001 (20130101) A63H 3/003 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/017 (20130101) G06F 3/167 (20130101) G06F 3/0346 (20130101) G06F 3/04815 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056329 | Dovichi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Norman Dovichi (South Bend, Indiana); Scott Sarver (South Bend, Indiana); Nicole Schiavone (South Bend, Indiana); Zhenbin Zhang (South Bend, Indiana); Liangliang Sun (South Bend, Indiana) |
| ABSTRACT | An electrokinetically pumped sheath flow nanospray interface for capillary electrophoresis coupled to negative mode electrospray mass spectrometer is described. At this interface, application of an electric field generates electro-osmotic flow at the interior of a glass emitter having an orifice. Electroosmotic flow pumps liquid around the distal tip of the separation capillary, ensheathing analyte into the electrospray electrolyte. In negative ion mode, negative potential applied to an untreated emitter drives sheath flow away from the emitter orifice, decreasing the stability and efficiency of the spray. In contrast, when the interior of the electrospray emitter is grafted with aminoalkylsilanes, the amines have a positive charge, which reverses electroosmosis and generates stable sheath flow to the emitter orifice under negative potential. Limits of detection were about 150 to 900 attomoles injected. Negative mode operation was demonstrated by analyzing a metabolite extract from stage 1 Xenopus laevis embryos. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 16/067032 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 30/7266 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057714 | Puria et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EarLens Corporation (Menlo Park, California) |
| ASSIGNEE(S) | Earlens Corporation (Menlo Park, California) |
| INVENTOR(S) | Sunil Puria (Boston, Massachusetts); Micha Rosen (Tzur Hadassah, Israel); Jonathan P. Fay (Dexter, Michigan); Paul Rucker (San Francisco, California); James Stone (Saratoga, California) |
| ABSTRACT | A device to transmit an audio signal to a user comprises a transducer and a support. The support is configured for placement on the eardrum to drive the eardrum. The transducer is coupled to the support at a first location to decrease occlusion and a second location to drive the eardrum. The transducer may comprise one or more of an electromagnetic balanced armature transducer, a piezoelectric transducer, a magnetostrictive transducer, a photostrictive transducer, or a coil and magnet. The device may find use with open canal hearing aids. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260684 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 11/02 (20130101) Original (OR) Class H04R 17/00 (20130101) H04R 23/008 (20130101) H04R 25/02 (20130101) H04R 25/65 (20130101) H04R 25/554 (20130101) H04R 25/606 (20130101) H04R 25/652 (20130101) H04R 2225/025 (20130101) H04R 2460/09 (20130101) H04R 2460/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057927 | Shepard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| ASSIGNEE(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| INVENTOR(S) | Clayton W. Shepard (Houston, Texas); Lin Zhong (Houston, Texas); Abeer Javed (Houston, Texas); Hang Yu (Houston, Texas) |
| ABSTRACT | Disclosed embodiments include methods for control channel design in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) wireless systems. A beacon comprising an identifier of a many-antenna base station is encoded into a base sequence. A plurality of synchronization sequences is generated based on the encoded base sequence and a set of orthogonal beam sequences. The many-antenna base-station transmits, using a plurality of antennas, the plurality of synchronization sequences in a plurality of beam directions associated with the set of orthogonal beam sequences for synchronization and associated with users without knowledge of channel state information (CSI). |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572577 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/046 (20130101) H04B 7/0417 (20130101) H04B 7/0452 (20130101) H04B 7/0456 (20130101) H04B 7/0617 (20130101) H04B 7/0695 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0053 (20130101) H04L 27/2613 (20130101) H04L 27/2692 (20130101) Wireless Communication Networks H04W 48/00 (20130101) H04W 56/001 (20130101) H04W 68/02 (20130101) H04W 72/14 (20130101) Original (OR) Class H04W 72/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057991 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Rak-Hwan Kim (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Described herein are flexible and stretchable LED arrays and methods utilizing flexible and stretchable LED arrays. Assembly of flexible LED arrays alongside flexible plasmonic crystals is useful for construction of fluid monitors, permitting sensitive detection of fluid refractive index and composition. Co-integration of flexible LED arrays with flexible photodetector arrays is useful for construction of flexible proximity sensors. Application of stretchable LED arrays onto flexible threads as light emitting sutures provides novel means for performing radiation therapy on wounds. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/942242 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/287 (20210101) A61B 5/6806 (20130101) A61B 5/6867 (20130101) A61B 5/6883 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0257 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/18 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 3/323 (20130101) H05K 2201/09263 (20130101) H05K 2201/10106 (20130101) H05K 2203/1316 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49128 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11051749 | Schalk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Health Research, Inc. (Menands, New York); Albany Medical College (Albany, New York) |
| ASSIGNEE(S) | Health Research, Inc. (Menands, New York); Albany Medical College (Albany, New York) |
| INVENTOR(S) | Gerwin Schalk (Glenmont, New York); Anthony L. Ritaccio (Voorheesville, New York); Adriana De Pesters (Coppet, Switzerland); AmiLyn Taplin (Albany, New York) |
| ABSTRACT | Provided is a method for mapping a neural area involved in speech processing, including applying a plurality of recording electrodes to a surface of a cortex of a human subject, presenting a plurality of auditory stimuli to the subject wherein some of the plurality of stimuli are speech sounds and others of the plurality of auditory stimuli are non-speech sounds, recording brain activity during the presenting of the plurality of auditory stimuli, and identifying one or more brain areas wherein activity changes more after presentation of speech sounds than it does after presentation of non-speech sounds, wherein the human subject does not speak during the presenting and the recording. Also provided is a method for mapping a neural area involved in speech production wherein the human subject does not speak during presenting speech stimuli and recording neural activity. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/570927 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/38 (20210101) Original (OR) Class A61B 5/4064 (20130101) A61B 5/4094 (20130101) A61B 2505/05 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/32 (20130101) A61N 1/0531 (20130101) A61N 1/36082 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051895 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Erik Mumm (Longmont, Colorado); Philip Chu (Friendswood, Texas); Nishant Kumar (Bergenfield, New Jersey); Jason Dumpert (Omaha, Nebraska); Yutaka Tsutano (Lincoln, Nebraska) |
| ABSTRACT | The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 16/689326 |
| ART UNIT | 2846 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/29 (20130101) A61B 17/00234 (20130101) A61B 34/00 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 34/37 (20160201) A61B 90/30 (20160201) A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11051998 | Powell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy E. Powell (Temecula, California) |
| ABSTRACT | A reconfigurable portable load bearing structure which can be configured into an extended load bearing configuration or a collapsed configuration, comprising of a first, second and third plurality of rail segments that are each rotatably coupled together and a plurality of support segments or pads which are configured to selectively couple and latch into one of a plurality of positions on said first, second and third plurality of rail segments. |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 16/823690 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 1/02 (20130101) A61G 1/003 (20130101) A61G 1/04 (20130101) A61G 1/007 (20130101) A61G 1/013 (20130101) Original (OR) Class A61G 7/103 (20130101) Construction of Bridges, or Viaducts; Assembly of Bridges E01D 15/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052151 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Elaine Hsiao (Rowland Heights, California); Sarkis K. Mazmanian (Porter Ranch, California); Paul H. Patterson (Altadena, California); Sara McBride (Pasadena, California) |
| ABSTRACT | Disclosed herein are compositions, systems, and methods for diagnosing and treatment of subjects suffering from anxiety, autism spectrum disorder (ASD), or a pathological condition with one or more of the symptoms of ASD. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/193724 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/7076 (20130101) G01N 2800/7085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052252 | Howard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Michael D. Howard (Westlake Village, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | Described is a system for weakening an undesirable memory. The system initiates application of a first pattern of spatiotemporally distributed transcranial stimulation via a set of electrodes to a subject who is in a calm mental state, causing association of the first pattern of spatiotemporally distributed transcranial stimulation with the calm mental state. The system then initiates application of the first pattern of spatiotemporally distributed transcranial stimulation via the set of electrodes when the undesirable memory is recalled by the subject, causing recall of the calm mental state and reconsolidation of the undesirable memory with the calm mental state. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/418920 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/369 (20210101) A61B 5/4836 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2021/0072 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/0484 (20130101) A61N 1/36025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052351 | Griswold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kimberly A. Griswold (Flanders, New Jersey); Scott Waisner (Vicksburg, Mississippi); Yao Chen (Brooklyn, New York) |
| ABSTRACT | The present invention is directed to rigid filtration apparatus comprising a filter support and filter membrane. Such filter support is comprised of a central core. Radiating from the central core are a plurality of pleats composed of two angled walls terminating at a contact point. Such longitudinal walls circumscribe a longitudinal channel situated between the walls wherein the longitudinal channel is in communication with the central core. The longitudinal walls are comprised of a plurality of openings along the walls. A filter membrane having biocidal components may be utilized with the filter support to effectively treat contaminated fluid, gas or air. Alternatively, the composition of the rigid central core and the rigid pleats may be composed of different materials to selectively remove chemicals, biological components or pharmaceuticals in a multi-stage treatment process. |
| FILED | Monday, March 19, 2018 |
| APPL NO | 15/924724 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 63/14 (20130101) B01D 63/067 (20130101) Original (OR) Class B01D 69/10 (20130101) B01D 69/145 (20130101) B01D 71/08 (20130101) B01D 71/38 (20130101) B01D 71/64 (20130101) B01D 2315/10 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 1/725 (20130101) C02F 2103/002 (20130101) C02F 2303/04 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052390 | Bernhards et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert C Bernhards (Abingdon, Maryland); Phillip M. Mach (Edgewood, Maryland); Kathleen J Quinn (Clifton, Virginia); Trevor G Glaros (North East, Maryland) |
| ABSTRACT | The invention is directed towards an Aerodynamic Automated Biological Assay Device (“AABAD”) comprising an aerodynamic substrate having a microfluidic cassette and an electronic module, and a system and a method of deploying the same to detect biological agents and hazards suspended in an atmosphere. The AABAD may be in the form/shape of a maple seed/fruit to induce autorotation. A plurality of AABADs are dispersed into the atmosphere from an aircraft or drone. The AABADs rotate via centrifugal forces without motor or active propulsion system while descending to the ground, wherein during the descent, the AABADs microfluidic cassettes collect and process the air samples via a centrifugal force formed from the autorotation generated by the airborne carrier, and to analyze and transmits the results to a remote location. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 16/444511 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2300/08 (20130101) B01L 2300/12 (20130101) B01L 2300/023 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/126 (20130101) B01L 2300/0851 (20130101) B01L 2400/0409 (20130101) B01L 2400/0627 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052899 | Shukla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| ASSIGNEE(S) | Oshkosh Defense, LLC (Oshkosh, Wisconsin) |
| INVENTOR(S) | Deepak Shukla (Oshkosh, Wisconsin); Rongjun Zhang (Oshkosh, Wisconsin); Nader Nasr (Neenah, Wisconsin) |
| ABSTRACT | A vehicle drive includes a gear set, a first motor/generator coupled to the gear set, a second motor/generator at least selectively rotationally engaged with the gear set, and an engine at least selectively coupled to the gear set and at least selectively coupled to the second motor/generator. The second motor/generator is electrically coupled to the first motor/generator by an electrical power transmission system. The first motor/generator and the second motor/generator are electrically coupled without an energy storage device configured to at least one of (a) provide electrical energy to the first motor/generator or the second motor/generator to power the first motor/generator or the second motor/generator and (b) be charged by electrical energy from the first motor/generator or the second motor/generator. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/547900 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/26 (20130101) B60K 6/34 (20130101) B60K 6/52 (20130101) B60K 6/365 (20130101) B60K 6/387 (20130101) B60K 6/445 (20130101) B60K 6/543 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/11 (20190201) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/02 (20130101) B60W 10/06 (20130101) B60W 10/08 (20130101) B60W 20/10 (20130101) Original (OR) Class B60W 2510/06 (20130101) B60W 2510/08 (20130101) B60W 2510/081 (20130101) B60W 2510/0604 (20130101) B60W 2510/0638 (20130101) B60W 2520/10 (20130101) B60W 2710/06 (20130101) B60W 2710/08 (20130101) B60W 2710/021 (20130101) B60W 2710/083 (20130101) B60W 2710/0644 (20130101) B60W 2710/0677 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/92 (20130101) B60Y 2300/42 (20130101) B60Y 2300/43 (20130101) B60Y 2300/60 (20130101) B60Y 2300/72 (20130101) B60Y 2400/72 (20130101) B60Y 2400/73 (20130101) Gearing F16H 1/28 (20130101) F16H 3/72 (20130101) F16H 3/727 (20130101) F16H 3/728 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/62 (20130101) Y02T 10/92 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 903/91 (20130101) Y10S 903/93 (20130101) Y10S 903/906 (20130101) Y10S 903/914 (20130101) Y10S 903/916 (20130101) Y10S 903/918 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052989 | Livieratos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Evangelos Livieratos (Manassas, Virginia); Cory Kays (Manassas, Virginia) |
| ABSTRACT | A wing-twist aircraft having a wing, an actuation system, a sensor, and/or a controller. The wing may have a wingspan that extends to a wing tip. The wing may further include a spar aligned in a span-wise direction, wherein at least one rib is operatively coupled to the spar. The actuation system may be configured to torsionally rotate the spar, which, in turn, torsionally rotates (pivots) the at least one rib coupled to the spar, thereby twisting the wing. The sensor may be configured to measure a characteristic of the wing, while the controller may be configured to command the actuation system to torsionally rotate the spar based at least in part on input from the sensor. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/701943 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/52 (20130101) Original (OR) Class B64C 9/10 (20130101) B64C 39/10 (20130101) B64C 2039/105 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053007 | Mills et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kendall Mills (Blairstown, New Jersey); Clinton Plaza (Easton, Pennsylvania); Juan Patino (West Milford, New Jersey); Lauren Morris (Midland Park, New Jersey); Zhaohua Luan (Ledgewood, New Jersey) |
| ABSTRACT | The present invention is directed to a device for dispensing pyrophoric decoy particulates where the device is comprised of at least one payload vessel having a structural wall that forms a cavity for housing a plurality of pyrophoric particles. The structural wall has at least one opening to facilitate dispersal of the pyrophoric particles. The payload vessels are inserted inside a tubular sleeve and hermetically sealed inside the sleeve. Within the sleeve the at least one payload vessel is also in direct contact with an expulsion assembly that upon activation pushes the payload vessels and its pyrophoric contents out of the sleeve to react with the air. |
| FILED | Monday, December 30, 2019 |
| APPL NO | 16/729664 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/08 (20130101) Original (OR) Class B64D 1/16 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053135 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aegis Technology Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Aegis Technology Inc. (Santa Ana, California) |
| INVENTOR(S) | Qi Chen (Santa Ana, California); Zhigang Lin (Santa Ana, California) |
| ABSTRACT | Producing CoxFe100-x, where x is an integer from 20 to 95, nanoparticles by: (a) providing a first aqueous hydroxide solution; (b) preparing a second aqueous solution containing iron ions and cobalt ions; and (c) depositing measured volumes of the second aqueous solution into the first aqueous solution whereby coprecipitation yields CoFe alloy nanoparticles, wherein step (c) occurs in an essentially oxygen-free environment. The nanoparticles are annealed at ambient temperatures to yield soft nanoparticles with targeted particle size, saturation magnetization and coercivity. The chemical composition, crystal structure and homogeneity are controlled at the atomic level. The CoFe magnetic nanoparticles have Ms of 200-235 emu/g, (Hc) coercivity of 18 to 36 Oe and size range of 5-40 nm. The high magnetic moment CoFe nanoparticles can be employed in drug delivery, superior contrast agents for highly sensitive magnetic resonance imaging, magnetic immunoassay, magnetic labeling, waste water treatment, and magnetic separation. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 16/403468 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0009 (20130101) C01G 51/003 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/04 (20130101) C01P 2004/64 (20130101) C01P 2006/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053169 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POWDERMET, INC. (Euclid, Ohio) |
| ASSIGNEE(S) | Powdermet, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257187 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/58 (20130101) C04B 35/515 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0645 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) C04B 2235/77 (20130101) C04B 2235/483 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/32 (20130101) C08J 9/35 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/24 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053209 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 16/611329 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053285 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
| ABSTRACT | The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020543 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/6075 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053481 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (Pasadena, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Tuesday, July 08, 2014 |
| APPL NO | 14/325815 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053492 | Brangwynne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Cliff Brangwynne (Hopewell, New Jersey); Dan Bracha (Princeton, New Jersey) |
| ABSTRACT | A system and method for reversibly controlling clustering of proteins around an engineered multivalent nucleus is disclosed. The system and method utilize clustering, which may be controlled by light activation or deactivation. The system and method enable the spatiotemporal control of protein supramolecular assemblies, including liquid-like droplets under some conditions, and solid-like gels under other conditions. The system and method can be utilized for segregating or locally concentrating desired proteins and/or RNA in cells or cell lysate, which may be useful for protein purification purposes, or for assembling single or multiple membraneless bodies within specific sub-regions of the cells. These synthetically assembled bodies may recruit both transgenic and endogenic proteins and other biomolecules, thus can be linked to affect and even trigger a plethora of cellular processes, including both physiological and pathological (e.g., protein aggregation) processes. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 16/704115 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/14 (20130101) C07K 2319/00 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053798 | Juh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Christopher M. Juh (Hobe Sound, Florida) |
| ABSTRACT | A trim balance device for a gas turbine engine having a rotatable shaft extending along a central longitudinal axis of the gas turbine engine includes a trim balance nut that is at least partially disposed about the rotatable shaft. The trim balance nut defines an aperture that extends from a first trim balance nut end towards a second trim balance nut end along the central longitudinal axis. The aperture being arranged to receive and seat a balance weight. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183008 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/027 (20130101) Original (OR) Class F01D 25/04 (20130101) Non-positive-displacement Pumps F04D 29/662 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/30 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 15/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053801 | Uskert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Richard C. Uskert (Timonium, Maryland); David J. Thomas (Brownsburg, Indiana); Wayne S. Steffier (Huntington Beach, California); Robert J. Shinavski (Mission Viejo, California); Adam L. Chamberlain (Mooresville, Indiana) |
| ABSTRACT | A gas turbine engine composite vane assembly and method for making same are disclosed. The method includes providing at least two gas turbine engine airfoil composite preform components. The airfoil composite preform components are interlocked with a first locking component so that mating faces of the airfoil composite preform components face each other. A filler material is inserted between the mating surfaces of the airfoil composite preform components. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201301 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/044 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/64 (20130101) F05D 2260/36 (20130101) F05D 2300/6012 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49229 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053949 | DeFelice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); David J. Zawilinski (W. Granby, Connecticut); Scott W. Simpson (Easthampton, Massachusetts) |
| ABSTRACT | A bleed valve includes a housing with an inlet coupled to an outlet by a duct. A guide tube is fixed within the housing between the inlet and the outlet. A piston with a piston orifice is slideably supported on the guide tube and movable between an open position and a closed position. The duct fluidly couples the inlet to the outlet in the open position, the duct fluidly separates the inlet from the outlet in the closed position, and the piston orifice fluidly couples the inlet with the outlet in the open position and the closed position to move piston between the open position and the closed position according to differential in pressure between the inlet and the outlet of the bleed valve. Compressors, gas turbine engines, and methods of controlling fluid flow are also described. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054889 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) F01D 17/145 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) F02C 9/18 (20130101) Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053962 | Corke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Thomas C. Corke (Granger, Indiana); Flint O. Thomas (Granger, Indiana) |
| ABSTRACT | A plasma plate is used to minimize drag of a fluid flow over an exposed surface. The plasma plate includes a series of plasma actuators positioned on the surface. Each plasma actuator is made of a dielectric separating a first electrode exposed to a fluid flow and a second electrode separated from the fluid flow under the dielectric. A pulsed direct current power supply provides a first voltage to the first electrode and a second voltage to the second electrode. The series of plasma actuators is operably connected to a bus which distribute powers and is positioned to minimize flow disturbances. The plasma actuators are arranged into a series of linear rows such that a velocity component is imparted to the fluid flow. |
| FILED | Friday, December 27, 2019 |
| APPL NO | 16/728924 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 23/005 (20130101) B64C 2230/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/172 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/12 (20130101) Original (OR) Class F15D 1/0075 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) H05H 2001/2412 (20130101) H05H 2001/2437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054224 | Stephens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Hunter I. Stephens (Hagatna, Guam); Anthony M. Mountain (West Springfield, Massachusetts); Kynan M. Valencia (Indianapolis, Indiana); Cory A. Cooper (Monument, Colorado) |
| ABSTRACT | A system for defeating a threat unmanned aerial vehicle including a friendly unmanned aerial vehicle and a containment system. The containment system is deployable from the friendly unmanned aerial vehicle and includes a signal blocking enclosure and a capturing device. The signal blocking enclosure is formed of a conductive material for shielding radio frequency signals from propagating in or out of the signal blocking enclosure. The capturing device is configured for arresting the threat unmanned aerial vehicle and positioning an arrested threat unmanned aerial vehicle within the signal blocking enclosure. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266405 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/02 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/04 (20130101) Original (OR) Class Secret Communication; Jamming of Communication H04K 3/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054230 | Pines et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Corey Pines (Alexandria, Virginia); Alexander Sweeney (Washington, District of Columbia); Taylor Young (Alexandria, Virginia); Steven Dunham (Alexandria, Virginia) |
| ABSTRACT | An anti-personnel mine that is flexible for manipulation in the field to accommodate missions by changing the shape of the C-4. The mine includes M112 seated in and adhered to a flexible housing having a rear involute wall. The involute wall includes a set of projecting folded pair of inclined walls that are about equidistant between a pair of inclined end walls. The inclined walls partitions most, but not all of the thickness of the M112 into segments that are tapered and accommodate the inclined walls. A metal spine, which may be shaped, is adhered to the front surface of the M112. Fragmentation elements and a bottom side of an elastic membrane are adhered to the spine and the front surface of the M112. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 15/998022 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/32 (20130101) F42B 23/10 (20130101) Original (OR) Class F42B 23/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054312 | Chernyak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Leonid Chernyak (Orlando, Florida); Robert E. Peale (Winter Park, Florida); Christopher J. Fredricksen (Orlando, Florida); Jonathan Lee (Orlando, Florida) |
| ABSTRACT | An IR sensor device may include an IR image sensor having an array of IR sensing pixels, and a readout circuit coupled to the IR image sensor and configured to sense sequential images. The IR sensor device may include a controller coupled to the readout circuit and configured to cause the readout circuit to apply a voltage to the IR image sensor between sensing of the sequential images. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/260861 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/06 (20130101) Original (OR) Class G01J 5/24 (20130101) G01J 2005/067 (20130101) G01J 2005/0077 (20130101) G01J 2005/202 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1462 (20130101) H01L 27/1465 (20130101) H01L 27/1469 (20130101) H01L 27/14694 (20130101) H01L 31/109 (20130101) H01L 31/184 (20130101) H01L 31/186 (20130101) H01L 31/0304 (20130101) H01L 31/02019 (20130101) H01L 31/035236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054340 | Khibnik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Alexander I. Khibnik (Glastonbury, Connecticut); Gregory S. Hagen (Glastonbury, Connecticut) |
| ABSTRACT | A method for foreign object debris detection in a gas turbine engine may comprise receiving, by a controller, a plurality of master configuration parameters, receiving, by the controller, a plurality of individual configuration parameters in response to the plurality of master configuration parameters, receiving, by the controller, a first time-series data from a database, pre-processing, by the controller, the first time-series data to generate a second time-series data, implementing, by the controller, an anomaly detector model, the anomaly detector model configured to generate a third time-series data, and implementing, by the controller, a foreign object debris (FOD) damage model, the FOD damage model receiving the third time-series data. The pre-processing the first time-series data, the implementing the anomaly detector model, and the implementing the FOD damage model may be defined by the plurality of individual configuration parameters. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 15/990200 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) F01D 21/10 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/80 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054345 | Sorensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kara C. Sorensen (San Diego, California); Ignacio D. Rivera (San Diego, California); Bart Chadwick (San Diego, California); Chuck Katz (San Diego, California); Cassandra Sosa (Chula Vista, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kara C. Sorensen (San Diego, California); Ignacio D. Rivera (San Diego, California); Bart Chadwick (San Diego, California); Chuck Katz (San Diego, California); Cassandra Sosa (Chula Vista, California) |
| ABSTRACT | A method for collecting samples of one or more substrate can include the steps of: A) providing a sample collection tube having a first end and a second end, B) providing a cap pivotable about the first end and a footplate pivotable about the second end, C) biasing the cap and the footplate closed so that a watertight compartment can be established inside the tube; D) forcing the cap and the footplate open by attaching the cap and footplate to a releasable fastener, E) positioning the sample collection tube into the one or more substrate to collect the sample, followed by F) releasing the cap and footplate from the releasable fastener so that a watertight compartment is established inside the tube when the cap and the footplate are closed. |
| FILED | Wednesday, July 17, 2019 |
| APPL NO | 16/514100 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) G01N 1/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054380 | Quevy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ProbiusDx, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | ProbiusDx, Inc. (El Cerrito, California) |
| INVENTOR(S) | Emmanuel Philippe Quevy (El Cerrito, California); Chaitanya Gupta (Redwood City, California); Jeremy Hui (San Francisco, California) |
| ABSTRACT | An all-electronic high-throughput detection system can perform multiple detections of one or more analyte in parallel. The detection system is modular, and can be easily integrated with existing microtiter plate technologies, automated test equipments and lab workflows (e.g., sample handling/distribution systems). The detection system includes multiple sensing modules that can perform separate analyte detection. A sensing module includes a platform configured to couple to a sample well. The sensing module also includes a sensor coupled to the platform. The sensing module further includes a first electrode coupled to the platform. The first electrode is configured to electrically connect with the sensor via a feedback circuit. The feedback circuit is configured to provide a feedback signal via the first electrode to a sample received in the sample well, the feedback signal based on a potential of the received sample detected via a second electrode. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/194208 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3273 (20130101) G01N 27/4045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054413 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart Martin (Severna Park, Maryland); Christopher M. Jewell (Silver Spring, Maryland); James I. Andorko (Delran, New Jersey); Elisabeth Lily Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Stuart Martin (Severna Park, Maryland); Christopher M. Jewell (Silver Spring, Maryland); James I. Andorko (Delran, New Jersey); Elisabeth Lily Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ABSTRACT | The present invention provides a device for assaying living cells comprising a substrate, wherein the substrate comprises one or more tethering molecules which adhere to the substrate and are capable of interacting with cell membranes of the cells, wherein the cells maintain a free-floating, non-adherent character when bound to the one or more tethering molecules. |
| FILED | Wednesday, October 07, 2015 |
| APPL NO | 14/877864 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95 (20130101) G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2800/7028 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054423 | Crowe, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Andrew I. Flyak (Nashville, Tennessee); Alexander Bukreyev (Galveston, Texas); Philipp Ilinykh (Galveston, Texas) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above. |
| FILED | Thursday, February 13, 2020 |
| APPL NO | 16/790658 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 39/395 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/10 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/577 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054428 | Bhatia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Leslie Wan-Gee Chan (Somerville, Massachusetts); Melodi Nilgun Anahtar (Cambridge, Massachusetts); Roderick Russell Kunz (Acton, Massachusetts) |
| ABSTRACT | In some aspects, the disclosure relates to compositions and method for detection, classification, and treatment of disease or other body status. The methods and compositions may be methods or compositions for identification of pathogenic infections or other diseases in patients using an inhalable nanosensor having a volatile reporter. The disclosure is based, in part, on synthetic biomarkers (e.g., inhalable nanosensors) that are capable of distinguishing (e.g., classifying) different disease or status associated enzymes in a subject by examining the effect of those enzymes on a synthetic volatile reporter. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/293390 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/497 (20130101) G01N 33/533 (20130101) G01N 33/569 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 2458/20 (20130101) G01N 2560/00 (20130101) G01N 2800/12 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054535 | Olesen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Robert Olesen (Fairborn, Ohio); Bryan Egner (Harrisburg, Pennsylvania); Darren Holland (Springfield, Ohio); Valerie Martin (Denver, Pennsylvania); James Bevins (Bellbrook, Ohio); Larry Burggraf (Washington Township, Ohio); Buckley O'Day (Dunn Loring, Virginia) |
| ABSTRACT | A directional radiation detection system and an omnidirectional radiation detector. The omnidirectional radiation detector detects radiation comprising at least one of: (i) gamma rays; and (ii) neutron particles. A radiation scatter mask (RSM) of the radiation detection system includes a rotating sleeve received over the omnidirectional radiation detector and rotating about a longitudinal axis. The RSM further includes: (i) a fin extending longitudinally from one side of the rotating sleeve; and (ii) a wall extending from the rotating sleeve and spaced apart from the fin having an upper end distally positioned on the rotating sleeve spaced apart or next to from a first lateral side of the fin and a lower end proximally positioned on the rotating sleeve and spaced apart from or next to a second lateral side of the fin. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/812844 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/15 (20130101) G01T 1/20 (20130101) G01T 3/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054590 | Wan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Noel Wan (Cambridge, Massachusetts); Jacques Johannes Carolan (Cambridge, Massachusetts); Tsung-Ju Lu (Cambridge, Massachusetts); Ian Robert Christen (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A process is provided for the high-yield heterogeneous integration of ‘quantum micro-chiplets’ (QMCs, diamond waveguide arrays containing highly coherent color centers) with an aluminum nitride (AlN) photonic integrated circuit (PIC). As an example, the process is useful for the development of a 72-channel defect-free array of germanium-vacancy (GeV) and silicon-vacancy (SiV) color centers in a PIC. Photoluminescence spectroscopy reveals long-term stable and narrow average optical linewidths of 54 MHz (146 MHz) for GeV (SiV) emitters, close to the lifetime-limited linewidth of 32 MHz (93 MHz). Additionally, inhomogeneities in the individual qubits can be compensated in situ with integrated tuning of the optical frequencies over 100 GHz. The ability to assemble large numbers of nearly indistinguishable artificial atoms into phase-stable PICs is useful for development of multiplexed quantum repeaters and general-purpose quantum computers. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734727 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055157 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Devavrat D. Shah (Waban, Massachusetts); Vinayak Ramesh (Cambridge, Massachusetts) |
| ABSTRACT | A method is disclosed including: receiving a graph-based program that identifies a bipartite graph and one or more update function sets, the bipartite graph including a plurality of graph nodes and a plurality of edges, such that each graph node corresponds to one of the update function sets; associating each of a plurality of computing units with a different respective one of the graph nodes; instantiating, by a Publisher Subscriber platform, a plurality of channels, the plurality of channels defining a topology that matches a topology of the bipartite graph; and executing the graph-based program based on the plurality of channels to produce a result. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683918 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) Original (OR) Class G06F 16/9024 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055232 | Keppel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | David Pardo Keppel (Mountain View, California); Binh Pham (Burlingame, California) |
| ABSTRACT | A processor includes a translation lookaside buffer (TLB) to store a TLB entry, wherein the TLB entry comprises a first set of valid bits to identify if the first TLB entry corresponds to a virtual address from a memory access request, wherein the valid bits are set based on a first page size associated with the TLB entry from a first set of different page sizes assigned to a first probe group; and a control circuit to probe the TLB for each page size of the first set of different page sizes assigned to the first probe group in a single probe cycle to determine if the TLB entry corresponds to the virtual address from the memory access request. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370848 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1009 (20130101) G06F 12/1036 (20130101) Original (OR) Class G06F 12/1045 (20130101) G06F 2212/657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055257 | Wadden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | John Pierson Wadden (Charlottesville, Virginia); Kevin Alan Angstadt (Madrid, New York) |
| ABSTRACT | The present disclosure relates to systems and methods for automatically optimizing a reporting architecture of an application. In one implementation, a system for automatically optimizing a reporting architecture of an application may include a memory storing instructions and an automata processor configured to execute the instructions. The instructions may include identifying one or more state transition elements in the application; determining if two or more state transition elements have disjoint character sets; grouping two or more state transition elements having disjoint character sets into one or more groups; merging state transition elements included in the one or more groups; and outputting a merged report configured for disambiguation on a second processor. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 15/590492 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 15/76 (20130101) G06F 15/80 (20130101) G06F 15/7867 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055555 | Sikka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Karan Sikka (Lawrenceville, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey); Ankan Bansal (College Park, Maryland) |
| ABSTRACT | A method, apparatus and system for zero shot object detection includes, in a semantic embedding space having embedded object class labels, training the space by embedding extracted features of bounding boxes and object class labels of labeled bounding boxes of known object classes into the space, determining regions in an image having unknown object classes on which to perform object detection as proposed bounding boxes, extracting features of the proposed bounding boxes, projecting the extracted features of the proposed bounding boxes into the space, computing a similarity measure between the projected features of the proposed bounding boxes and the embedded, extracted features of the bounding boxes of the known object classes in the space, and predicting an object class label for proposed bounding boxes by determining a nearest embedded object class label to the projected features of the proposed bounding boxes in the space based on the similarity measures. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/383447 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/628 (20130101) G06K 9/726 (20130101) G06K 9/2054 (20130101) Original (OR) Class G06K 9/3241 (20130101) G06K 9/6215 (20130101) G06K 9/6262 (20130101) G06K 2009/6213 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055609 | Modha |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | In one embodiment, the present invention provides a neural network circuit comprising multiple symmetric core circuits. Each symmetric core circuit comprises a first core module and a second core module. Each core module comprises a plurality of electronic neurons, a plurality of electronic axons, and an interconnection network comprising multiple electronic synapses interconnecting the axons to the neurons. Each synapse interconnects an axon to a neuron. The first core module and the second core module are logically overlayed on one another such that neurons in the first core module are proximal to axons in the second core module, and axons in the first core module are proximal to neurons in the second core module. Each neuron in each core module receives axonal firing events via interconnected axons and generates a neuronal firing event according to a neuronal activation function. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/162003 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/90335 (20190101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/04 (20130101) G06N 3/06 (20130101) G06N 3/049 (20130101) G06N 3/061 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055671 | Rose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | David Rose (Ava, New York); Matthew J. Rothgeb (Springfield, Ohio); Douglas S. Dudis (Tipp City, Ohio); Nicholas S. Wilson (Springboro, Ohio); Douglas C Hansen (Dayton, Ohio) |
| ABSTRACT | In accordance with various embodiments of the disclosed subject matter, a system and method is configured for generating maintenance events in response to threshold levels of accumulated corrosive stresses experienced by assets or components thereof based on environmental and weather data correlated to respective locations visited and a model of corrosive susceptibility of the assets or components thereof. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/211448 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0075 (20130101) Meteorology G01W 1/02 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055844 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Xiangxue Wang (Cleveland Heights, Ohio); Cristian Barrera (Cleveland, Ohio); Vamsidhar Velcheti (Pepper Pike, Ohio) |
| ABSTRACT | Embodiments access a digitized image of tissue demonstrating non-small cell lung cancer (NSCLC), the tissue including a plurality of cellular nuclei; segment the plurality of cellular nuclei represented in the digitized image; extract a set of nuclear radiomic features from the plurality of segmented cellular nuclei; generate at least one nuclear cell graph (CG) based on the plurality of segmented nuclei; compute a set of CG features based on the nuclear CG; provide the set of nuclear radiomic features and the set of CG features to a machine learning classifier; receive, from the machine learning classifier, a probability that the tissue will respond to immunotherapy, based, at least in part, on the set of nuclear radiomic features and the set of CG features; generate a classification of the tissue as a responder or non-responder based on the probability; and display the classification. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/281324 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00147 (20130101) G06K 9/469 (20130101) G06K 9/6257 (20130101) G06K 9/6262 (20130101) G06K 9/6267 (20130101) G06K 2209/05 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 7/62 (20170101) G06T 2207/10056 (20130101) G06T 2207/20072 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056090 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Theodore P. Martin (Delmar, New York); Charles Alan Rohde (Brentwood, Maryland); Gregory Orris (Kensington, Maryland); Kristin Charipar (Alexandria, Virginia); Alberto Piqué (Crofton, Maryland) |
| ABSTRACT | A device for use in a medium comprising a medium vibro-acoustic impedance. The device includes an elastic material including a plurality of unit cells. The plurality of unit cells includes a first unit cell. The first unit cell includes a first unit-cell joint comprising a first unit-cell joint wall defining a first joint central void, a first unit-cell joint inclusion located in the first joint central void, and at least two first unit-cell arms connected to and extending away from the first unit-cell joint. The elastic material includes an elastic-material vibro-acoustic impedance. The elastic-material vibro-acoustic impedance and the medium vibro-acoustic impedance are sufficiently vibro-acoustically impedance-matched to couple time-varying, propagating vibro-acoustic fields between said elastic material and the medium. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/049943 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/02 (20130101) G10K 11/04 (20130101) G10K 11/162 (20130101) Original (OR) Class G10K 11/205 (20130101) G10K 2200/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056314 | Hujsak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Karl A. Hujsak (Evanston, Illinois); Vinayak P. Dravid (Evanston, Illinois); Benjamin D. Myers (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure involve a data capturing and processing system that intentionally captures data and/or data sets with missing pieces of information. The data and/or datasets may include various types of data, such as one-dimensional signals, two-dimensional images (or other images), and/or three-dimensional structures. The captured data is processed to restore missing information into the data and/or data sets, thereby enabling simultaneous pattern recognition and image recovery. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332573 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10061 (20130101) G06T 2207/20081 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056448 | Forte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Domenic J. Forte (Gainesville, Florida); Bicky Shakya (San Diego, California); Haoting Shen (Verdi, Nevada); Mark M. Tehranipoor (Gainesville, Florida) |
| ABSTRACT | Integrated circuit (IC) camouflaging has emerged as a promising solution for protecting semiconductor intellectual property (IP) against reverse engineering. The cell camouflaging covert gate leverages doping and dummy contacts to create camouflaged cells that are indistinguishable from regular standard cells under modern imaging techniques. A comprehensive security analysis of the covert gate shows that it achieves high resiliency against SAT and test-based attacks at very low overheads. Models are derived to characterize the covert cells, and metrics are developed to incorporate them into a gate-level design. Simulation results of overheads and attacks are presented on benchmark circuits. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 16/797695 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76831 (20130101) H01L 21/823807 (20130101) H01L 21/823871 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/5226 (20130101) H01L 27/092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056602 | Ordonez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard C. Ordonez (Mililani, Hawaii); Carlos M. Torres, Jr. (San Diego, California); Cody K. Hayashi (Waipahu, Hawaii); David Garmire (Honolulu, Hawaii) |
| ABSTRACT | A graphene device for filtering color, involving a graphene structure responsive to continuous in-situ electrical gate-tuning of a Fermi level thereof and a plurality of nanoparticles disposed in relation to the graphene structure, each portion of the plurality of nanoparticles having a distinct energy bandgap in relation to another portion of the plurality of nanoparticles, and each portion of the plurality of nanoparticles configured to one of activate and deactivate in relation to the distinct energy bandgap and in response to the in-situ electrical gate-tuning of the Fermi level of the graphene structure. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 16/447652 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02376 (20130101) H01L 21/02603 (20130101) H01L 29/1606 (20130101) H01L 31/09 (20130101) H01L 31/028 (20130101) H01L 31/101 (20130101) Original (OR) Class H01L 31/0352 (20130101) H01L 31/1136 (20130101) H01L 31/1804 (20130101) H01L 31/02165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056791 | Zekios et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Muhammad Hamza (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Muhammad Hamza (Miami, Florida) |
| ABSTRACT | Antenna devices are provided, including tightly coupled arrays, transmitarrays, and reflectarrays. An antenna device can include a plurality of substrates each having an antenna element. The substrates can be provided in connected series or in an array. The substrates can be part of an origami array such that the entire array is foldable. The substrates can optionally be attached to a framework that can actuate the substrates to different configurations. By bending, folding, or otherwise repositioning the substrates/array, the electromagnetic characteristics of the antenna device can be easily reconfigured for the desired task. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680673 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/08 (20130101) H01Q 1/38 (20130101) H01Q 9/285 (20130101) H01Q 9/0414 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056860 | Familiant et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eaton Intelligent Power Limited (Dubin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (, None) |
| INVENTOR(S) | Yakov Lvovich Familiant (Thiensville, Wisconsin); Andrew A. Rockhill (Waukesha, Wisconsin); Paul J. Rollmann (Menomonee Falls, Wisconsin) |
| ABSTRACT | An apparatus includes a plurality of semiconductor switches. A first bus interconnects first terminals of the semiconductor switches in a first chain and provides a first impedance between the first terminals of switches of the first chain. A second bus interconnects second terminals of the semiconductor switches in a second chain and provides a second impedance greater that the first impedance between the second terminals of the switches of the second chain. The apparatus may be implemented as a laminated bus assembly including respective overlapping conductor plates, wherein the second bus includes a plate having subregions defined by features, such as slots or grooves, that provide the second impedance. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/599955 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/52 (20130101) H01L 25/072 (20130101) Boards, Substations, or Switching Arrangements for the Supply or Distribution of Electric Power H02B 1/20 (20130101) Original (OR) Class Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 5/005 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/003 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/02 (20130101) H05K 7/1432 (20130101) H05K 2201/10272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056962 | Kao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Calvin Kao (Santa Clarita, California) |
| ABSTRACT | In one embodiment, an aircraft includes a wing operable to fold along a wing fold gap. The wing comprises an inboard edge flap and an outboard edge flap, wherein the wing fold gap is between the inboard edge flap and the outboard edge flap. The aircraft further includes an input shaft operably coupled to the inboard edge flap, the input shaft mechanically coupled to a first magnetic torque coupler assembly at a first end of the input shaft. The wing further includes an output shaft operably coupled to the outboard edge flap, the output shaft mechanically coupled to a second magnetic torque coupler assembly at a first end of the output shaft. The first magnetic torque coupler assembly may magnetically couple to the second magnetic torque coupler assembly across the fold gap. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 15/880622 |
| ART UNIT | 2832 — Electrical Circuits and Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/56 (20130101) Dynamo-electric Machines H02K 49/10 (20130101) H02K 49/104 (20130101) H02K 49/108 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057033 | Van Brunt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Edward Robert Van Brunt (Raleigh, North Carolina); Adam Barkley (Durham, North Carolina); Sei-Hyung Ryu (Cary, North Carolina); Zachary Cole (Summers, Arkansas); Kraig J. Olejniczak (Rogers, Arkansas) |
| ABSTRACT | A power module includes a plurality of power semiconductor devices. The plurality of power semiconductor devices includes an insulated gate bipolar transistor (IGBT) and a metal-oxide-semiconductor field-effect transistor (MOSFET) coupled in parallel between a first power switching terminal and a second power switching terminal. The IGBT and the MOSFET are silicon carbide devices. By providing the IGBT and the MOSFET together, a tradeoff between forward conduction current and reverse conduction current of the power module, the efficiency, and the specific current rating of the power module may be improved. Further, providing the IGBT and the MOSFET as silicon carbide devices may significantly improve the performance of the power module. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 16/504908 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1608 (20130101) Pulse Technique H03K 17/62 (20130101) H03K 17/76 (20130101) H03K 17/567 (20130101) Original (OR) Class H03K 17/693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057438 | Bronner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Derek P. Bronner (Chittenango, New York); Robert A. Joyce (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York); Julia A. Baker (Ithaca, New York) |
| ABSTRACT | This disclosure provides example techniques to invoke one or more tools, with an investigative tool. The investigative tool provides a common framework that allows investigators to invoke their own trusted tools or third-party generated tools. The investigative tool described herein seamlessly and transparently invokes the tools in accordance with an investigative profile created by the investigator. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 15/999568 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057740 | Duchon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Eric N. Duchon (Arlington, Massachusetts); I-Ju L. Nelson (Lexington, Massachusetts); Sarah E. Li (Cambridge, Massachusetts); Helen M. Vo (South Lake Tahoe, California); Daniel I. Zwillinger (Newton, Massachusetts) |
| ABSTRACT | Techniques are provided for implementing a custodianship model for decentralized track fusion. A methodology implementing the techniques according to an embodiment includes negotiating, between a first decentralized track fuser (DTF) and one or more peer DTFs. The method also includes accepting, by the first DTF, custodianship of a track of an object from one of the peer DTFs based on a first negotiation. The method further includes updating, by the first DTF, the track based on fusion of data items associated with the track. The data items are received from one or more of the peer DTFs. The method further includes transferring, by the first DTF, custodianship of the updated track to one of the peer DTFs based on a second negotiation. In some cases, the transfer may be initiated by detection of a failure state of the first DTF. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588237 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00805 (20130101) G06K 9/6288 (20130101) Wireless Communication Networks H04W 4/029 (20180201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057991 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Rak-Hwan Kim (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Described herein are flexible and stretchable LED arrays and methods utilizing flexible and stretchable LED arrays. Assembly of flexible LED arrays alongside flexible plasmonic crystals is useful for construction of fluid monitors, permitting sensitive detection of fluid refractive index and composition. Co-integration of flexible LED arrays with flexible photodetector arrays is useful for construction of flexible proximity sensors. Application of stretchable LED arrays onto flexible threads as light emitting sutures provides novel means for performing radiation therapy on wounds. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/942242 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/287 (20210101) A61B 5/6806 (20130101) A61B 5/6867 (20130101) A61B 5/6883 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0257 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/18 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 3/323 (20130101) H05K 2201/09263 (20130101) H05K 2201/10106 (20130101) H05K 2203/1316 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49128 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057994 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson Air Force Base, Ohio) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson Air Force Base, Ohio) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Ethan B. Secor (Stillwater, Minnesota); Alexander B. Cook (Beavercreek, Ohio); Christopher Tabor (Wright-Patterson Air Force Base, Ohio) |
| ABSTRACT | Articles, electronic devices and related methods of fabrication interfacing graphene with a gallium liquid metal alloy. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/648275 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/16 (20130101) H05K 1/032 (20130101) H05K 1/092 (20130101) Original (OR) Class H05K 1/0277 (20130101) H05K 1/0292 (20130101) H05K 3/1283 (20130101) H05K 2201/0154 (20130101) H05K 2201/0323 (20130101) H05K 2201/10053 (20130101) H05K 2203/1194 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11052195 | Atterbury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | William G. Atterbury (Columbus, Ohio); Douglas E. Boyd (Columbus, Ohio) |
| ABSTRACT | The invention provides methods and apparatus for injecting a medicine, especially a highly viscous medicine. Conventional methods and apparatus for injecting viscous medicines suffer from a variety of problems such as excessive force during the initial needle insertion and initial injection. In an inventive method, during the initial phase of the injection, energy is stored in a torsion spring that is subsequently released during a later stage of the injection. The present invention also provides for an improved autoinjector; especially via the use of a combination compression and torsion spring that powers the injection through controlling force applied to a plunger via a screw flange or nut having pins that ride in a prescribed path down the length of the autoinjector. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/742507 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/326 (20130101) A61M 5/2033 (20130101) Original (OR) Class A61M 5/3155 (20130101) A61M 5/3287 (20130101) A61M 5/31583 (20130101) A61M 2005/206 (20130101) A61M 2005/2073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052353 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut) |
| ASSIGNEE(S) | Praxair Technology, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Zigui Lu (East Amherst, New York); Yunxiang Lu (Williamsville, New York); Gervase Maxwell Christie (Amherst, New York); Jonathan A. Lane (Snyder, New York); Pawel J. Plonczak (Amherst, New York); Joseph M. Corpus (Avon, Indiana) |
| ABSTRACT | A method is described of producing a catalyst-containing composite oxygen ion membrane and a catalyst-containing composite oxygen ion membrane in which a porous fuel oxidation layer and a dense separation layer and optionally, a porous surface exchange layer are formed on a porous support from mixtures of (Ln1−xAx)wCr1−yByO3−δ and a doped zirconia. Adding certain catalyst metals into the fuel oxidation layer not only enhances the initial oxygen flux, but also reduces the degradation rate of the oxygen flux over long-term operation. One of the possible reasons for the improved flux and stability is that the addition of the catalyst metal reduces the chemical reaction between the (Ln1−xAx)wCr1−yByO3−δ and the zirconia phases during membrane fabrication and operation, as indicated by the X-ray diffraction results. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 16/085786 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 67/0041 (20130101) Original (OR) Class B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 71/024 (20130101) B01D 2257/104 (20130101) B01D 2323/12 (20130101) B01D 2323/18 (20130101) B01D 2325/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/46 (20130101) B01J 23/86 (20130101) B01J 23/462 (20130101) B01J 23/862 (20130101) B01J 35/002 (20130101) B01J 35/023 (20130101) B01J 35/065 (20130101) B01J 35/1076 (20130101) B01J 37/0018 (20130101) B01J 37/0244 (20130101) B01J 37/0248 (20130101) B01J 2523/23 (20130101) B01J 2523/24 (20130101) B01J 2523/31 (20130101) B01J 2523/37 (20130101) B01J 2523/47 (20130101) B01J 2523/67 (20130101) B01J 2523/72 (20130101) B01J 2523/821 (20130101) B01J 2523/822 (20130101) B01J 2523/824 (20130101) B01J 2523/828 (20130101) B01J 2523/842 (20130101) B01J 2523/845 (20130101) B01J 2523/847 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 18/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/0255 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 35/01 (20130101) C04B 35/016 (20130101) C04B 35/44 (20130101) C04B 35/462 (20130101) C04B 35/2641 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 2111/0081 (20130101) C04B 2111/00801 (20130101) C04B 2235/80 (20130101) C04B 2235/442 (20130101) C04B 2235/443 (20130101) C04B 2235/658 (20130101) C04B 2235/768 (20130101) C04B 2235/3208 (20130101) C04B 2235/3213 (20130101) C04B 2235/3224 (20130101) C04B 2235/3225 (20130101) C04B 2235/3227 (20130101) C04B 2235/3229 (20130101) C04B 2235/3241 (20130101) C04B 2235/3246 (20130101) C04B 2235/3274 (20130101) C04B 2235/3275 (20130101) C04B 2235/3279 (20130101) C04B 2235/3289 (20130101) C04B 2235/5445 (20130101) C04B 2235/6583 (20130101) C04B 2237/34 (20130101) C04B 2237/58 (20130101) C04B 2237/343 (20130101) C04B 2237/348 (20130101) C04B 2237/765 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052374 | de Leon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Patricia Ignacio de Leon (Westmont, Illinois); Philip D. Laible (Downers Grove, Illinois); Mackenzie Elizabeth Meyer (Ann Arbor, Michigan); Christopher R. Povinelli (Milwaukee, Wisconsin); Killian L. Tracey (Geneva, Illinois); Daniel Yoav Arenas (Chicago, Illinois) |
| ABSTRACT | A process for separations and recovery from mixtures via specific adsorption using high-surface area, flexible silica-based nanostructured gel adsorbents and articles of manufacture relating to same. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/228593 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) B01J 20/103 (20130101) Original (OR) Class B01J 20/223 (20130101) B01J 20/3064 (20130101) B01J 20/3085 (20130101) B01J 20/3204 (20130101) B01J 20/3265 (20130101) B01J 20/3268 (20130101) B01J 20/28047 (20130101) B01J 20/28085 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/163 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052375 | Baumann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California); Joseph C. Farmer (Tracy, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California); Joseph C. Farmer (Tracy, California) |
| ABSTRACT | An adsorptive cooling system includes: a first highly adsorptive structure positioned to receive thermal energy from a thermal energy source, the first highly adsorptive structure including: a first substrate; and a first carbon aerogel adhered to the first substrate, a second highly adsorptive structure positioned to receive thermal energy from the thermal energy source, the second highly adsorptive structure including: a second substrate; and a second carbon aerogel adhered to the second substrate, a cooling unit; and a circulation system adapted for circulating the refrigerant from at least one of the first highly adsorptive structure and the second highly adsorptive structure to the cooling unit to provide cooling from the thermal energy source and to return the refrigerant from the cooling unit to at least one of the first highly adsorptive structure and the second highly adsorptive structure. |
| FILED | Thursday, April 26, 2012 |
| APPL NO | 13/457338 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/20 (20130101) Original (OR) Class B01J 20/103 (20130101) B01J 20/2804 (20130101) B01J 20/3085 (20130101) B01J 20/28042 (20130101) B01J 20/28047 (20130101) B01J 20/28052 (20130101) B01J 20/28066 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/047 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/083 (20130101) F25B 27/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053181 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Zhenglong Li (Knoxville, Tennessee) |
| ABSTRACT | A catalyst composition for converting an alcohol to olefins, the catalyst composition comprising the following components: (a) beta zeolite; (b) at least one element selected from the group consisting of zinc, magnesium, calcium, strontium, sodium, and potassium; and (c) at least one element selected from the group consisting of hafnium, yttrium, zirconium, tantalum, niobium, and tin; wherein the components (b) and (c) are independently within or on a surface of said beta zeolite. The catalyst may also further include component (d), which is copper or silver. Also described herein is a method for converting an alcohol to one or more olefinic compounds, the method comprising contacting the alcohol with a catalyst at a temperature of at least 100° C. and up to 500° C. to result in the alcohol being converted to the one or more olefinic compounds. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530397 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/06 (20130101) B01J 29/7007 (20130101) B01J 29/7057 (20130101) B01J 29/7215 (20130101) B01J 29/7415 (20130101) B01J 29/7615 (20130101) B01J 35/0006 (20130101) B01J 35/0073 (20130101) B01J 37/04 (20130101) B01J 37/30 (20130101) B01J 37/0036 (20130101) B01J 37/0201 (20130101) B01J 37/0207 (20130101) B01J 2229/16 (20130101) B01J 2229/18 (20130101) B01J 2229/20 (20130101) B01J 2229/37 (20130101) B01J 2229/186 (20130101) Acyclic or Carbocyclic Compounds C07C 1/20 (20130101) C07C 1/24 (20130101) C07C 11/02 (20130101) Original (OR) Class C07C 11/04 (20130101) C07C 11/06 (20130101) C07C 11/08 (20130101) C07C 11/12 (20130101) C07C 11/16 (20130101) C07C 11/167 (20130101) C07C 2529/74 (20130101) C07C 2529/76 (20130101) C07C 2529/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053322 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Juntao Luo (Jamesville, New York); Wei He (Davis, California); Kit S. Lam (Davis, California); Paul Henderson (Dublin, California); Matthew A. Coleman (Oakland, California) |
| ABSTRACT | The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a polyethylene glycol) polymer; each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 15/499855 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/775 (20130101) C07K 17/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053356 | Grubbs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Robert H Grubbs (South Pasadena, California); Tzu-Pin Lin (Pasadena, California); Alice Chang (Los Angeles, California); Hsiang-Yun Chen (Pasadena, California); Christopher M Bates (Santa Barbara, California) |
| ABSTRACT | In an aspect, a method of synthesizing a graft copolymer comprises the steps of: copolymerizing a first macromonomer and a first reactive diluent; wherein said first macromonomer comprises a first backbone precursor directly or indirectly covalently linked to a first polymer side chain group; wherein said reactive diluent is provided in the presence of the first macromonomer at an amount selected so as to result in formation said graft copolymer having a first backbone incorporating said diluent and said first macromonomer in a first polymer block characterized by a preselected first graft density or a preselected first graft distribution of said first macromonomer. In some embodiments of this aspect, said preselected first graft density is any value selected from the range of 0.05 to 0.75. In some methods, the composition and amount of said diluent is selected to provide both a first preselected first graft density and a first preselected first graft distribution. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914762 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 267/10 (20130101) C08F 285/00 (20130101) C08F 287/00 (20130101) C08F 290/02 (20130101) C08F 290/04 (20130101) C08F 290/04 (20130101) C08F 290/06 (20130101) C08F 290/06 (20130101) C08F 290/042 (20130101) C08F 290/044 (20130101) C08F 290/046 (20130101) C08F 290/048 (20130101) C08F 290/061 (20130101) C08F 290/062 (20130101) C08F 290/064 (20130101) C08F 290/065 (20130101) C08F 290/067 (20130101) C08F 290/068 (20130101) C08F 293/00 (20130101) C08F 293/005 (20130101) C08F 2500/09 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 81/021 (20130101) Original (OR) Class C08G 2261/126 (20130101) C08G 2261/128 (20130101) C08G 2261/136 (20130101) C08G 2261/144 (20130101) C08G 2261/148 (20130101) C08G 2261/149 (20130101) C08G 2261/418 (20130101) C08G 2261/722 (20130101) C08G 2261/1424 (20130101) C08G 2261/1426 (20130101) C08G 2261/1428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053512 | Cushman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (Reno, Nevada) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
| INVENTOR(S) | John C. Cushman (Reno, Nevada); Sung Don Lim (Reno, Nevada) |
| ABSTRACT | Disclosed herein are methods of altering tissue succulence in plants. In some examples, a disclosed method includes overexpressing a modified helix-loop-helix transcription factor CEB1 in a plant cell, thereby altering plant succulence. The disclosed methods can be used to improve the drought and salinity tolerance of plants, such as in plants in arid or saline environments, and also enhance the ability of plants to perform. Also disclosed are CEB1 nucleic acids and transgenic plants containing such nucleic acids. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977930 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8201 (20130101) C12N 15/8225 (20130101) C12N 15/8226 (20130101) C12N 15/8234 (20130101) C12N 15/8273 (20130101) Original (OR) Class C12N 15/8279 (20130101) C12N 15/8294 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053597 | Biener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Monika M. Biener (San Leandro, California); Juergen Biener (San Leandro, California); Siwei Liang (Dublin, California); Zhen Qi (Tracy, California); Michael Stadermann (Pleasanton, California); Vedasri Vedharathinam (Fremont, California) |
| ABSTRACT | A flow-through electrolysis cell includes a hierarchical nanoporous metal cathode. A method of reducing CO2 includes flowing the CO2 through the hierarchical nanoporous metal cathode of the flow-through electrolysis cell. |
| FILED | Thursday, April 05, 2018 |
| APPL NO | 15/946424 |
| ART UNIT | 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 9/19 (20210101) C25B 11/031 (20210101) C25B 11/057 (20210101) Original (OR) Class C25B 11/061 (20210101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053601 | Rowen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Adam M. Rowen (Livermore, California); Robert K. Grubbs (Albuquerque, New Mexico); Jonathan Joseph Coleman (Albuquerque, New Mexico) |
| ABSTRACT | A method for electroplating a nonmetallic grating including providing a nonmetallic grating; performing an atomic layer deposition (ALD) reaction to form a seed layer on the nonmetallic grating; and electroplating a metallic layer on the seed layer such that the metallic layer uniformly and conformally coats the nonmetallic grating. An apparatus including a silicon substrate having gratings with an aspect-ratio of at least 20:1; a atomic layer deposition (ALD) seed layer formed on the gratings; and an electroplated metallic layer formed on the seed layer, wherein the electroplated metallic layer uniformly and conformally coats the gratings. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/174744 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/18 (20130101) C23C 16/045 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) C23C 16/45561 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/48 (20130101) Original (OR) Class C25D 5/18 (20130101) C25D 7/123 (20130101) C25D 17/02 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) G21K 1/025 (20130101) G21K 2207/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053603 | Pascall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Andrew J. Pascall (Livermore, California); Hannah Grace Coe (Livermore, California); Julie A. Jackson (Livermore, California); Susant K. Patra (Brentwood, California) |
| ABSTRACT | A method of producing a complex product includes designing a three dimensional preform of the complex product, creating a three dimensional preform of the complex product using the model, depositing a material on the preform, and removing the preform to complete the complex product. In one embodiment the system provides a complex heat sink that can be used in heat dissipation in power electronics, light emitting diodes, and microchips. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/250206 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 26/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/003 (20130101) C25D 13/02 (20130101) Original (OR) Class C25D 13/12 (20130101) C25D 15/00 (20130101) C25D 15/02 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 2021/0029 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/12 (20130101) F28F 21/02 (20130101) F28F 21/04 (20130101) F28F 21/08 (20130101) F28F 2260/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4935 (20150115) Y10T 29/49982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053801 | Uskert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Richard C. Uskert (Timonium, Maryland); David J. Thomas (Brownsburg, Indiana); Wayne S. Steffier (Huntington Beach, California); Robert J. Shinavski (Mission Viejo, California); Adam L. Chamberlain (Mooresville, Indiana) |
| ABSTRACT | A gas turbine engine composite vane assembly and method for making same are disclosed. The method includes providing at least two gas turbine engine airfoil composite preform components. The airfoil composite preform components are interlocked with a first locking component so that mating faces of the airfoil composite preform components face each other. A filler material is inserted between the mating surfaces of the airfoil composite preform components. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201301 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) Original (OR) Class F01D 5/282 (20130101) F01D 9/044 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/64 (20130101) F05D 2260/36 (20130101) F05D 2300/6012 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49229 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053949 | DeFelice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Robert DeFelice (South Windsor, Connecticut); David J. Zawilinski (W. Granby, Connecticut); Scott W. Simpson (Easthampton, Massachusetts) |
| ABSTRACT | A bleed valve includes a housing with an inlet coupled to an outlet by a duct. A guide tube is fixed within the housing between the inlet and the outlet. A piston with a piston orifice is slideably supported on the guide tube and movable between an open position and a closed position. The duct fluidly couples the inlet to the outlet in the open position, the duct fluidly separates the inlet from the outlet in the closed position, and the piston orifice fluidly couples the inlet with the outlet in the open position and the closed position to move piston between the open position and the closed position according to differential in pressure between the inlet and the outlet of the bleed valve. Compressors, gas turbine engines, and methods of controlling fluid flow are also described. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/054889 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) F01D 17/145 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) F02C 9/18 (20130101) Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054268 | Klenk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | Matthew Klenk (San Francisco, California); Victoria M. Bellotti (Oakland, California); Shiwali Mohan (Palo Alto, California) |
| ABSTRACT | Systems and methods described receive a request for a transportation plan for a user, wherein the request comprises a starting point and an ending point for a route. Systems and methods then generate a set of potential transportation plans for the route, determine an impact of a subset of plans in the set of potential transportation plans and estimate a likelihood of acceptance of the subset of plans in the set of potential transportation plans based on a personal preference model for the user. Systems and methods also select an influence strategy of the user based on a user model and generate a message recommending a selected plan from the subset of plans for the user, wherein the message is generated based on the selected influence strategy. |
| FILED | Monday, November 05, 2018 |
| APPL NO | 16/181152 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3461 (20130101) G01C 21/3484 (20130101) Original (OR) Class G01C 21/3605 (20130101) G01C 21/3676 (20130101) G01C 21/3697 (20130101) Electric Digital Data Processing G06F 16/29 (20190101) G06F 16/2379 (20190101) G06F 16/24575 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054367 | Holman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hoi-Ying N. Holman (Oakland, California); Kevin Loutherback (Berkeley, California); Liang Chen (Walnut Creek, California) |
| ABSTRACT | Disclosed herein are systems, methods, systems and devices for measurement and visualization of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying time-dependent spectral features indicative of chemical abnormality in individual cells. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/766594 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2200/0647 (20130101) B01L 2300/161 (20130101) B01L 2300/0877 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/031 (20130101) G01N 21/35 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 27/026 (20130101) G01N 2021/3595 (20130101) G01N 2201/129 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054375 | Seidler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Gerald Todd Seidler (Seattle, Washington); Oliver Hoidn (Seattle, Washington); William Holden (Seattle, Washington) |
| ABSTRACT | A spectrometer includes a crystal analyzer having a radius of curvature that defines a Rowland circle, a sample stage configured to support a sample such that the sample is offset from the Rowland circle, an x-ray source configured to emit unfocused x-rays toward the sample stage, and a position-sensitive detector that is tangent to the Rowland circle. A method performed via a spectrometer includes emitting, via an x-ray source, unfocused x-rays toward a sample that is mounted on a sample stage such that the sample is offset from the Rowland Circle, thereby causing the sample to emit x-rays that impinge on the crystal analyzer or transmit a portion of the unfocused x-rays to impinge on the crystal analyzer; scattering, via the crystal analyzer, the x-rays that impinge on the crystal analyzer; and detecting the scattered x-rays via a position-sensitive detector that is tangent to the Rowland circle. |
| FILED | Friday, September 15, 2017 |
| APPL NO | 16/333405 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) G01N 23/207 (20130101) G01N 23/2076 (20130101) Original (OR) Class G01N 23/20008 (20130101) G01N 23/20025 (20130101) G01N 23/20091 (20130101) G01N 2223/32 (20130101) G01N 2223/052 (20130101) G01N 2223/307 (20130101) G01N 2223/309 (20130101) G01N 2223/5015 (20130101) G01N 2291/045 (20130101) Measurement of Nuclear or X-radiation G01T 1/2978 (20130101) G01T 7/10 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0816 (20130101) G02B 27/0983 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 2201/062 (20130101) G21K 2201/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054481 | Christophersen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Jon P. Christophersen (Moscow, Idaho); John L. Morrison (Butte, Montana); William H. Morrison (Butte, Montana) |
| ABSTRACT | Impedance testing devices, circuits, systems, and related methods are disclosed. A Device Under Test (DUT) is excited with a multispectral excitation signal for an excitation time period while the DUT is under a load condition from a load operably coupled to the DUT. A response of the DUT is sampled over a sample time period. The sample time period is configured such that it includes an in-band interval during the excitation time period and one or more out-of-band intervals outside of the in-band interval. A response of the DUT to the load condition during the in-band interval is estimated by analyzing samples of the response from the one or more out-of-band intervals. Adjusted samples are computed by subtracting the estimated load response during the in-band interval from the samples from the in-band interval. An impedance of the DUT is estimated by analyzing the adjusted samples. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/357865 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/389 (20190101) Original (OR) Class G01R 31/392 (20190101) G01R 31/3648 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/482 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054544 | Kroc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Thomas K Kroc (Batavia, Illinois); Robert Kephart (Pioneer, California) |
| ABSTRACT | A system, method, and apparatus for wellbore inspection comprise an electron accelerator to generate X-rays, a rotating collimator assembly configured to produce a cone of X-rays, and at least one detector assembly configured to collect backscattered X-rays. A position assembly can be provided to move the electron accelerator, rotating collimator assembly, and detector through a wellbore. A computer system is configured to receive data from the detector and generate an image of the wellbore. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/043047 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) G01N 23/203 (20130101) G01N 2223/616 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/12 (20130101) Original (OR) Class G01V 5/0025 (20130101) G01V 5/045 (20130101) Optical Elements, Systems, or Apparatus G02B 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054590 | Wan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Noel Wan (Cambridge, Massachusetts); Jacques Johannes Carolan (Cambridge, Massachusetts); Tsung-Ju Lu (Cambridge, Massachusetts); Ian Robert Christen (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A process is provided for the high-yield heterogeneous integration of ‘quantum micro-chiplets’ (QMCs, diamond waveguide arrays containing highly coherent color centers) with an aluminum nitride (AlN) photonic integrated circuit (PIC). As an example, the process is useful for the development of a 72-channel defect-free array of germanium-vacancy (GeV) and silicon-vacancy (SiV) color centers in a PIC. Photoluminescence spectroscopy reveals long-term stable and narrow average optical linewidths of 54 MHz (146 MHz) for GeV (SiV) emitters, close to the lifetime-limited linewidth of 32 MHz (93 MHz). Additionally, inhomogeneities in the individual qubits can be compensated in situ with integrated tuning of the optical frequencies over 100 GHz. The ability to assemble large numbers of nearly indistinguishable artificial atoms into phase-stable PICs is useful for development of multiplexed quantum repeaters and general-purpose quantum computers. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734727 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054637 | O'Neill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mission Support and Test Services, LLC (Las Vegas, Nevada) |
| ASSIGNEE(S) | Mission Support and Test Services, LLC (North Las Vegas, Nevada) |
| INVENTOR(S) | Mary D. O'Neill (Santa Barbara, California); David Terry (Santa Barbara, California) |
| ABSTRACT | A compact adaptive optics system for long-range horizontal paths imaging that improves degraded images. The system uses a filter that corresponds to the three colors in a typical color detector element, one or more optic elements, a deformable mirror, and a detector. Focus errors, due to turbulence, in the image recorded by the detector element show up as image shifts in the three distinct color images. The shifts and statistics of these shifts between these simultaneous images are used to create control signals for the deformable mirror resulting in a compact adaptive optic system for horizontal paths without need for a point source located at the distance scene being imaged. Analysis of the relative pixel shifts in various regions of the image provides third order statistics revealing tip/tilt and additional Zernikes modes that are used to control a deformable mirror without the need for a guide star/point-source. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/231023 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/46 (20130101) G01J 3/51 (20130101) G01J 9/00 (20130101) G01J 2009/002 (20130101) Optical Elements, Systems, or Apparatus G02B 26/06 (20130101) G02B 27/017 (20130101) G02B 27/0068 (20130101) Original (OR) Class G02B 2027/011 (20130101) G02B 2027/014 (20130101) G02B 2027/0112 (20130101) G02B 2027/0138 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/10032 (20130101) Pictorial Communication, e.g Television H04N 5/357 (20130101) H04N 9/0455 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056313 | Poelker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | jefferson science associates, llc (Newport News, Virginia) |
| INVENTOR(S) | Bernard Matthew Poelker (Yorktown, Virginia); Gabriel Gerardo Palacios Serrano (Yorktown, Virginia); Carlos Hernandez Garcia (Yorktown, Virginia) |
| ABSTRACT | An integral Wien filter and vacuum pump for separating charged particles or for orienting their spin direction while maintaining optimal beamline vacuum. The vacuum pump is an ion pump including one or more cylindrical Penning cells to trap and expel electrons. The Wien filter includes orthogonal electric and magnetic fields to direct particles with the desired speed through the device while deflecting particles at undesired speeds. The Wien filter includes two electrodes, one biased positive and one biased negative, a dipole magnet, and means for reversing polarity of the electrodes to flip the spin of the charged particles. Metal plates on either side of the Penning cells embed gas that is ionized by trapped electrons in the Penning cell thus creating vacuum by turning gas into solid. The two metal plates can be configured to obtain vacuum pumping via chemical gettering and for removal of noble gases. |
| FILED | Thursday, June 18, 2020 |
| APPL NO | 16/904910 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/05 (20130101) H01J 37/18 (20130101) Original (OR) Class H01J 2237/057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056314 | Hujsak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Karl A. Hujsak (Evanston, Illinois); Vinayak P. Dravid (Evanston, Illinois); Benjamin D. Myers (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure involve a data capturing and processing system that intentionally captures data and/or data sets with missing pieces of information. The data and/or datasets may include various types of data, such as one-dimensional signals, two-dimensional images (or other images), and/or three-dimensional structures. The captured data is processed to restore missing information into the data and/or data sets, thereby enabling simultaneous pattern recognition and image recovery. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332573 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10061 (20130101) G06T 2207/20081 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056332 | Maunz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Peter Lukas Wilhelm Maunz (Albuquerque, New Mexico); Matthew G. Blain (Albuquerque, New Mexico); Christopher Nordquist (Albuquerque, New Mexico) |
| ABSTRACT | A radio-frequency (RF) surface ion trap chip includes an RF electrode and an integrated capacitive voltage divider in which an intermediate voltage node is capacitively connected between the RF electrode and a ground. A sensor output trace is connected to the intermediate voltage node. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821150 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Electric Discharge Tubes or Discharge Lamps H01J 49/0018 (20130101) H01J 49/422 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056413 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xin Zhang (Yorktown Heights, New York); Todd Takken (Brewster, New York); Shurong Tian (Mount Kisco, New York); Yuan Yao (Tarrytown, New York) |
| ABSTRACT | An inductor includes a conductor having a first end and a second end, wherein the first end, the second end, or both ends are configured to be mounted on a substrate and configured to receive a heat flow; and one or more magnetic cores surrounding a first portion of the conductor, the first portion of the conductor being intermediate the first end and the second end of the conductor. A second portion of the conductor not surrounded by the one or more magnetic cores is configured to transfer the heat flow from the conductor. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/417845 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/367 (20130101) Original (OR) Class H01L 23/645 (20130101) H01L 28/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056448 | Forte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Domenic J. Forte (Gainesville, Florida); Bicky Shakya (San Diego, California); Haoting Shen (Verdi, Nevada); Mark M. Tehranipoor (Gainesville, Florida) |
| ABSTRACT | Integrated circuit (IC) camouflaging has emerged as a promising solution for protecting semiconductor intellectual property (IP) against reverse engineering. The cell camouflaging covert gate leverages doping and dummy contacts to create camouflaged cells that are indistinguishable from regular standard cells under modern imaging techniques. A comprehensive security analysis of the covert gate shows that it achieves high resiliency against SAT and test-based attacks at very low overheads. Models are derived to characterize the covert cells, and metrics are developed to incorporate them into a gate-level design. Simulation results of overheads and attacks are presented on benchmark circuits. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 16/797695 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76831 (20130101) H01L 21/823807 (20130101) H01L 21/823871 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 23/5226 (20130101) H01L 27/092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056680 | Vissers |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vissers Battery Corporation (Wheaton, Illinois) |
| ASSIGNEE(S) | Vissers Battery Corporation (Wheaton, Illinois) |
| INVENTOR(S) | Daniel R. Vissers (Wheaton, Illinois) |
| ABSTRACT | A battery includes negative electrode material and positive electrode material where the materials are in a solid phase except for selected portions that are heated to transform the selected portions into a fluid. The fluid portion of negative electrode material is directed to a negative electrode region of a reaction chamber and the fluid portion of positive electrode material is directed to a positive electrode region of the reaction chamber where a solid electrolyte containing ions of the negative electrode separates the positive electrode region from the negative electrode region. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 15/982455 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/0471 (20130101) Original (OR) Class H01M 10/39 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056685 | Wong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Stanislaus Wong (Upton, New York); Lei Wang (Port Jefferson, New York); Coray McBean (Malverne, New York); Amy C. Marschilok (Stony Brook, New York); Kenneth Takeuchi (Stony Brook, New York); Esther S. Takeuchi (Stony Brook, New York) |
| ABSTRACT | A method of fabricating nanocomposite anode material embodying a lithium titanate (LTO)-multi-walled carbon nanotube (MWNT) composite intended for use in a lithium-ion battery includes providing multi-walled carbon nanotube (MWNTs), including nanotube surfaces, onto which functional oxygenated carboxylic acid moieties are arranged, generating 3D flower-like, lithium titanate (LTO) microspheres, including thin nanosheets and anchoring the acid-functionalized MWNTs onto surfaces of the 3D LTO microspheres by π-π interaction strategy to realize the nanocomposite anode material. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/250907 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 4/523 (20130101) H01M 4/587 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056705 | Sanford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Melanie S. Sanford (Ann Arbor, Michigan); Christo Slavov Sevov (Ann Arbor, Michigan); Rachel Brooner (Midland, Michigan); Etienne Chénard (Urbana, Illinois) |
| ABSTRACT | Organic anolyte materials for redox flow batteries and redox flow batteries containing organic anolyte materials are disclosed. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/580048 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 213/51 (20130101) C07D 213/55 (20130101) C07D 213/56 (20130101) C07D 213/89 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/368 (20130101) H01M 4/9008 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 10/0567 (20130101) H01M 10/0569 (20130101) H01M 50/40 (20210101) H01M 2300/0028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056791 | Zekios et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Muhammad Hamza (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Muhammad Hamza (Miami, Florida) |
| ABSTRACT | Antenna devices are provided, including tightly coupled arrays, transmitarrays, and reflectarrays. An antenna device can include a plurality of substrates each having an antenna element. The substrates can be provided in connected series or in an array. The substrates can be part of an origami array such that the entire array is foldable. The substrates can optionally be attached to a framework that can actuate the substrates to different configurations. By bending, folding, or otherwise repositioning the substrates/array, the electromagnetic characteristics of the antenna device can be easily reconfigured for the desired task. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680673 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/08 (20130101) H01Q 1/38 (20130101) H01Q 9/285 (20130101) H01Q 9/0414 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057072 | Welsh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Raphael Joseph Welsh (Powell, Ohio); Douglas A. Thornton (Upper Arlington, Ohio); Daniel A. Perkins (Lewis Center, Ohio); Micah Blue (Columbus, Ohio); Amy M. Heintz (Dublin, Ohio); Daniel G. Loesch (Sunbury, Ohio) |
| ABSTRACT | A radio frequency (RF) aperture includes an interface board. An array of electrically conductive tapered projections have bases disposed on a front side of the interface printed circuit board and extend away from the front side of the interface printed circuit board. RF circuitry is disposed at the back side of the interface board and is electrically connected with the electrically conductive tapered projections. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/858169 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057438 | Bronner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Derek P. Bronner (Chittenango, New York); Robert A. Joyce (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York); Julia A. Baker (Ithaca, New York) |
| ABSTRACT | This disclosure provides example techniques to invoke one or more tools, with an investigative tool. The investigative tool provides a common framework that allows investigators to invoke their own trusted tools or third-party generated tools. The investigative tool described herein seamlessly and transparently invokes the tools in accordance with an investigative profile created by the investigator. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 15/999568 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057740 | Duchon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Eric N. Duchon (Arlington, Massachusetts); I-Ju L. Nelson (Lexington, Massachusetts); Sarah E. Li (Cambridge, Massachusetts); Helen M. Vo (South Lake Tahoe, California); Daniel I. Zwillinger (Newton, Massachusetts) |
| ABSTRACT | Techniques are provided for implementing a custodianship model for decentralized track fusion. A methodology implementing the techniques according to an embodiment includes negotiating, between a first decentralized track fuser (DTF) and one or more peer DTFs. The method also includes accepting, by the first DTF, custodianship of a track of an object from one of the peer DTFs based on a first negotiation. The method further includes updating, by the first DTF, the track based on fusion of data items associated with the track. The data items are received from one or more of the peer DTFs. The method further includes transferring, by the first DTF, custodianship of the updated track to one of the peer DTFs based on a second negotiation. In some cases, the transfer may be initiated by detection of a failure state of the first DTF. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588237 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00805 (20130101) G06K 9/6288 (20130101) Wireless Communication Networks H04W 4/029 (20180201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057991 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Rak-Hwan Kim (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Described herein are flexible and stretchable LED arrays and methods utilizing flexible and stretchable LED arrays. Assembly of flexible LED arrays alongside flexible plasmonic crystals is useful for construction of fluid monitors, permitting sensitive detection of fluid refractive index and composition. Co-integration of flexible LED arrays with flexible photodetector arrays is useful for construction of flexible proximity sensors. Application of stretchable LED arrays onto flexible threads as light emitting sutures provides novel means for performing radiation therapy on wounds. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/942242 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/287 (20210101) A61B 5/6806 (20130101) A61B 5/6867 (20130101) A61B 5/6883 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0257 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/18 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 3/323 (20130101) H05K 2201/09263 (20130101) H05K 2201/10106 (20130101) H05K 2203/1316 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49128 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11051711 | Lattanzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Riccardo Lattanzi (New York, New York); Daniel K. Sodickson (New York, New York); José E. Cruz Serralles (Cambridge, Massachusetts); Athanasios Polymeridis (Moscow, Russian Federation); Luca Daniel (Cambridge, Massachusetts); Jacob K. White (Cambridge, Massachusetts) |
| ABSTRACT | A plurality of stimulations is transmitted to tissue or other material using one or more transmitters. The plurality of signals associated with the excited tissue and the transmitted stimulations are measured. The measured signals are processed to generate field-related quantities, such as B1+ and/or MR signal maps. Field-related quantities are generated also from simulation, by calculating the one or more incident fields from a simulator model of the one or more transmitters and assuming a given distribution of electrical properties in the tissue or other material. Field-related quantities generated from simulation and experimental procedures are compared to each other. The assumed electrical properties distribution is updated and the procedure is repeated iteratively until the difference between simulated and experimental field-related quantities is smaller than a threshold. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/494384 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00011 (20130101) A61B 5/0004 (20130101) A61B 5/0013 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 2576/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/48 (20130101) G01R 33/56 (20130101) G01R 33/246 (20130101) G01R 33/4616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052044 | Brea Fernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roberto Javier Brea Fernandez (San Diego, California); Christian Cole (Del Mar, California); Neal K. Devaraj (La Jolla, California); Brent Lyda (San Diego, California); Roger Sunahara (San Diego, California) |
| ABSTRACT | Described herein, inter alia, are compositions and methods useful for the reconstitution of membrane proteins. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 16/489783 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1277 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/106 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/14 (20130101) Peptides C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052151 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Elaine Hsiao (Rowland Heights, California); Sarkis K. Mazmanian (Porter Ranch, California); Paul H. Patterson (Altadena, California); Sara McBride (Pasadena, California) |
| ABSTRACT | Disclosed herein are compositions, systems, and methods for diagnosing and treatment of subjects suffering from anxiety, autism spectrum disorder (ASD), or a pathological condition with one or more of the symptoms of ASD. |
| FILED | Friday, November 16, 2018 |
| APPL NO | 16/193724 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/28 (20130101) G01N 2800/7076 (20130101) G01N 2800/7085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052153 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yuan Yao (West Lafayette, Indiana); Jingmin Joanne Zhang (West Lafayette, Indiana) |
| ABSTRACT | Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described. |
| FILED | Monday, October 08, 2018 |
| APPL NO | 16/153893 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/73 (20130101) A61K 31/192 (20130101) A61K 31/343 (20130101) A61K 47/36 (20130101) Original (OR) Class A61K 2800/49 (20130101) A61K 2800/544 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052395 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Mohammad Aghaamoo (Irvine, California); Xuan Li (Irvine, California); Neha Garg (Irvine, California); Yu-Hsi Chen (Irvine, California) |
| ABSTRACT | The present invention features the use of lateral cavity acoustic transducers (LCATs) to apply mechanical stimuli on cells. LCATs utilize the generated acoustic microstreaming vortices to trap cells and apply tunable shear-induced cell deformation on them. The present invention may use such a portable, automated, and high throughput device for shear-induced cell transfection. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547152 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502769 (20130101) B01L 2200/18 (20130101) B01L 2200/0647 (20130101) B01L 2300/06 (20130101) B01L 2300/0645 (20130101) B01L 2300/0809 (20130101) B01L 2400/0415 (20130101) B01L 2400/0436 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052407 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Arum Han (College Station, Texas); Song-I Han (College Station, Texas) |
| ABSTRACT | A dielectrophoresis-based in-droplet cell concentrator is disclosed herein. The concentrator can include a concentration microchannel having an input port and two or more outlet ports. The input port introduces cell-encapsulated droplets or particle-encapsulated droplets into the microchannel; a first outlet port receives droplets including most of the cells or particles and a second output port receives droplets including few cells or particles. The concentrator also can include a pair of electrodes. When voltage is applied, the electrodes will create an electric field across the microchannel. The concentrator adds new capabilities to droplet microfluidics operations, such as adjusting concentrations of cells in droplets, separating cells of different properties from inside droplets, and solution exchange. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257783 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/0652 (20130101) B01L 2300/0809 (20130101) B01L 2400/043 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/026 (20130101) Original (OR) Class B03C 2201/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052597 | MacCurdy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert Bruce MacCurdy (Belchertown, Massachusetts); Daniela Rus (Weston, Massachusetts); Jeffrey Ian Lipton (Medford, Massachusetts) |
| ABSTRACT | Described is a method of forming a structure having viscoelastic properties. The method can include a) depositing a layer of droplets of a solidifying material and a non-solidifying material, the droplets being deposited according to an occupancy matrix specifying voxels for the solidifying and non-solidifying materials, the solidifying and non-solidifying material being interspersed within the occupancy matrix, the occupancy matrix being generated by a probabilistic function; b) exposing the droplets of solidifying material to ultraviolet radiation to cure the solidifying material; and c) repeating a) and b) to deposit additional layers of droplets of solidifying and non-solidifying materials, thereby forming the structure having viscoelastic properties. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/597068 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 64/129 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053134 | Weller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jon Mark Weller (Phoenix, Arizona); Candace Chan (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jon Mark Weller (Phoenix, Arizona); Candace Chan (Phoenix, Arizona) |
| ABSTRACT | Synthesizing lithium lanthanum zirconate includes combining a reagent composition with a salt composition to yield a molten salt reaction medium, wherein the reagent composition comprises a lithium component, a lanthanum component, and zirconium component having a lithium:lanthanum:zirconium molar ratio of about 7:3:2; heating the molten salt reaction medium to yield a reaction product; and washing the reaction product to yield a crystalline powder comprising lithium lanthanum zirconate. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/111939 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/76 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/51 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053209 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Tonia S. Ahmed (Pasadena, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycles using a stereoretentive, ruthenium-based catalyst supported by a dithiolate ligand is reported. This catalyst is demonstrated to be remarkably active as observed in initiation experiments showing complete catalyst initiation at −20° C. within 10 min. Using easily accessible diene starting materials bearing a Z-olefin moiety, macrocyclization reactions generated products with significantly higher Z-selectivity in appreciably shorter reaction times, in higher yield, and with much lower catalyst loadings than in previously reported systems. Macrocyclic lactones ranging in size from twelve-membered to seventeen-membered rings are synthesized in moderate to high yields (68-79% yield) with excellent Z-selectivity (95%-99% Z). |
| FILED | Tuesday, April 24, 2018 |
| APPL NO | 16/611329 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2291 (20130101) B01J 2231/543 (20130101) B01J 2531/821 (20130101) Heterocyclic Compounds C07D 313/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053356 | Grubbs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Robert H Grubbs (South Pasadena, California); Tzu-Pin Lin (Pasadena, California); Alice Chang (Los Angeles, California); Hsiang-Yun Chen (Pasadena, California); Christopher M Bates (Santa Barbara, California) |
| ABSTRACT | In an aspect, a method of synthesizing a graft copolymer comprises the steps of: copolymerizing a first macromonomer and a first reactive diluent; wherein said first macromonomer comprises a first backbone precursor directly or indirectly covalently linked to a first polymer side chain group; wherein said reactive diluent is provided in the presence of the first macromonomer at an amount selected so as to result in formation said graft copolymer having a first backbone incorporating said diluent and said first macromonomer in a first polymer block characterized by a preselected first graft density or a preselected first graft distribution of said first macromonomer. In some embodiments of this aspect, said preselected first graft density is any value selected from the range of 0.05 to 0.75. In some methods, the composition and amount of said diluent is selected to provide both a first preselected first graft density and a first preselected first graft distribution. |
| FILED | Wednesday, March 07, 2018 |
| APPL NO | 15/914762 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 267/10 (20130101) C08F 285/00 (20130101) C08F 287/00 (20130101) C08F 290/02 (20130101) C08F 290/04 (20130101) C08F 290/04 (20130101) C08F 290/06 (20130101) C08F 290/06 (20130101) C08F 290/042 (20130101) C08F 290/044 (20130101) C08F 290/046 (20130101) C08F 290/048 (20130101) C08F 290/061 (20130101) C08F 290/062 (20130101) C08F 290/064 (20130101) C08F 290/065 (20130101) C08F 290/067 (20130101) C08F 290/068 (20130101) C08F 293/00 (20130101) C08F 293/005 (20130101) C08F 2500/09 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 81/021 (20130101) Original (OR) Class C08G 2261/126 (20130101) C08G 2261/128 (20130101) C08G 2261/136 (20130101) C08G 2261/144 (20130101) C08G 2261/148 (20130101) C08G 2261/149 (20130101) C08G 2261/418 (20130101) C08G 2261/722 (20130101) C08G 2261/1424 (20130101) C08G 2261/1426 (20130101) C08G 2261/1428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053480 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Jose Hernandez-Lozada (Jena, Germany); Costas Maranas (State College, Pennsylvania); Matthew Grisewood (Mountaintop, Pennsylvania) |
| ABSTRACT | Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ. ID. NO: 1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, M141, E142, Y145, and L146, gene constructs encoding and configured to express the mutated thioesterases in a transformed host cell and host cells transformed to contain the gene constructs. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 15/930147 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054357 | Ozcan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Yichen Wu (Los Angeles, California); Steve Wei Feng (Los Angeles, California) |
| ABSTRACT | A lens-free microscope for monitoring air quality includes a housing that contains a vacuum pump configured to draw air into an impaction nozzle. The impaction nozzle has an output located adjacent to an optically transparent substrate for collecting particles. One or more illumination sources are disposed in the housing and are configured to illuminate the collected particles on the optically transparent substrate. An image sensor is located adjacent to the optically transparent substrate, wherein the image sensor collects particle diffraction patterns or holographic images cast upon the image sensor. At least one processor is disposed in the housing and controls the vacuum pump and the one or more illumination sources. Image files are transferred to a separate computing device for image processing using machine learning to identify particles and perform data analysis to output particle images, particle size, particle density, and/or particle type data. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 16/492098 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0227 (20130101) Original (OR) Class G01N 15/0255 (20130101) G01N 15/0612 (20130101) G01N 15/1434 (20130101) G01N 2015/0046 (20130101) G01N 2015/144 (20130101) G01N 2015/0233 (20130101) G01N 2015/1454 (20130101) G01N 2015/1488 (20130101) G01N 2015/1493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054422 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sheng-He Huang (Arcadia, California); Alec Chan (San Gabriel, California) |
| ASSIGNEE(S) | Sheng-He Huang (Arcadia, California); Alec Chan (San Gabriel, California) |
| INVENTOR(S) | Sheng-He Huang (Arcadia, California) |
| ABSTRACT | The invention provides the use of circulating astrocytes (cAstr) and the Major Facilitator Superfamily Domain containing Protein 2a (Mfsd2a) as biomarkers, and their combined use with other related circulating markers (cBMEC and EPC) in early detection and diagnosis of cerebrovascular diseases (CVD) or central nervous system (CNS) disorders. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431559 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 45/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class G01N 2333/70571 (20130101) G01N 2800/50 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054440 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ming Liu (Riverside, California); Ruoxue Yan (Riverside, California) |
| ABSTRACT | A method for generating a high-intensity light source at a probe tip, the method includes exciting a TM0 mode of a surface plasmon polariton (SPP) in a sharp-tip metal nanowire (AgNW) waveguide with a linearly-polarized mode (LP01) in a tapered optical fiber (OF); and compressing the TM0 mode through a chemically-sharpened taper to a tip apex of the sharp-tip silver nanowire (AgNW). |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834326 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 20/02 (20130101) Original (OR) Class G01Q 30/02 (20130101) G01Q 60/16 (20130101) G01Q 60/22 (20130101) G01Q 60/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054590 | Wan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Noel Wan (Cambridge, Massachusetts); Jacques Johannes Carolan (Cambridge, Massachusetts); Tsung-Ju Lu (Cambridge, Massachusetts); Ian Robert Christen (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A process is provided for the high-yield heterogeneous integration of ‘quantum micro-chiplets’ (QMCs, diamond waveguide arrays containing highly coherent color centers) with an aluminum nitride (AlN) photonic integrated circuit (PIC). As an example, the process is useful for the development of a 72-channel defect-free array of germanium-vacancy (GeV) and silicon-vacancy (SiV) color centers in a PIC. Photoluminescence spectroscopy reveals long-term stable and narrow average optical linewidths of 54 MHz (146 MHz) for GeV (SiV) emitters, close to the lifetime-limited linewidth of 32 MHz (93 MHz). Additionally, inhomogeneities in the individual qubits can be compensated in situ with integrated tuning of the optical frequencies over 100 GHz. The ability to assemble large numbers of nearly indistinguishable artificial atoms into phase-stable PICs is useful for development of multiplexed quantum repeaters and general-purpose quantum computers. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734727 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054662 | Mendis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island); OSAKA UNIVERSITY (Osaka, Japan) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island); Osaka University (Osaka, Japan) |
| INVENTOR(S) | Rajind Mendis (Providence, Rhode Island); Masaya Nagai (Osaka, Japan); Daniel M. Mittleman (Providence, Rhode Island) |
| ABSTRACT | A polarizing beam splitter includes thin electrically conductive metal sheets each having an edge and a thickness substantially less than the wavelength λ of a terahertz signal. The sheets are arranged in a stack or array to define wave propagation passages for energy of a terahertz beam directed at a face formed by edges of the sheets, and constitutes an artificial dielectric which operates below cutoff to allow selective transmission through the passages and/or reflection from said face, separating polarization states of the beam with defined power splitting. The artificial dielectric beam splitter can be configured to operate over a broad terahertz band. The sheets are flat, without micropatterned surface features, are robust and simple to manufacture, and form a broad band polarizing beam slitter for terahertz radiation. Complete separation of the transmitted and reflected beam is achieved below cutoff by rotating the polarization of the input beam. |
| FILED | Monday, December 11, 2017 |
| APPL NO | 16/467780 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/3058 (20130101) G02B 27/283 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054807 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandeep K. S. Gupta (Tempe, Arizona); Ayan Banerjee (Tempe, Arizona); Imane Lamrani (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Sandeep K. S. Gupta (Tempe, Arizona); Ayan Banerjee (Tempe, Arizona); Imane Lamrani (Tempe, Arizona) |
| ABSTRACT | Systems and methods for mining hybrid automata from input-output traces of cyber-physical systems are disclosed herein. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/413018 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4155 (20130101) Original (OR) Class G05B 2219/35261 (20130101) G05B 2219/37496 (20130101) Electric Digital Data Processing G06F 7/552 (20130101) G06F 17/12 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055157 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Devavrat D. Shah (Waban, Massachusetts); Vinayak Ramesh (Cambridge, Massachusetts) |
| ABSTRACT | A method is disclosed including: receiving a graph-based program that identifies a bipartite graph and one or more update function sets, the bipartite graph including a plurality of graph nodes and a plurality of edges, such that each graph node corresponds to one of the update function sets; associating each of a plurality of computing units with a different respective one of the graph nodes; instantiating, by a Publisher Subscriber platform, a plurality of channels, the plurality of channels defining a topology that matches a topology of the bipartite graph; and executing the graph-based program based on the plurality of channels to produce a result. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683918 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) Original (OR) Class G06F 16/9024 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055351 | Shyu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chi-Ren Shyu (Columbia, Missouri); Michael Phinney (Columbia, Missouri) |
| ABSTRACT | The present disclosure relates to a persistent data structure employed as a tree structure with a frequent pattern mining paradigm. The number of nodes in the tree structure scales linearly with respect to the number unique items within the itemsets associated with the nodes. With the disclosed pattern mining paradigm, compressed representations of maximal patterns may be mined with the goal of detecting a frequent maximal pattern covers in a top down approach. Thus, large patterns are detected before their subsets yielding a significant reduction in computation time. The persistent data structure is a dynamic data structure which may be updated to add or delete nodes or transactional information without the need for recreating the entire tree structure. Furthermore, the persistent data structure may be run by a computing system either locally or on a parallelized distributed computing architecture to increase operational performance. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955462 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) G06F 16/2246 (20190101) G06F 16/2379 (20190101) G06F 16/2465 (20190101) G06F 16/9027 (20190101) Original (OR) Class G06F 2216/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056314 | Hujsak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Karl A. Hujsak (Evanston, Illinois); Vinayak P. Dravid (Evanston, Illinois); Benjamin D. Myers (Evanston, Illinois) |
| ABSTRACT | Aspects of the present disclosure involve a data capturing and processing system that intentionally captures data and/or data sets with missing pieces of information. The data and/or datasets may include various types of data, such as one-dimensional signals, two-dimensional images (or other images), and/or three-dimensional structures. The captured data is processed to restore missing information into the data and/or data sets, thereby enabling simultaneous pattern recognition and image recovery. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332573 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/005 (20130101) G06T 2207/10061 (20130101) G06T 2207/20081 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/222 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056705 | Sanford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Melanie S. Sanford (Ann Arbor, Michigan); Christo Slavov Sevov (Ann Arbor, Michigan); Rachel Brooner (Midland, Michigan); Etienne Chénard (Urbana, Illinois) |
| ABSTRACT | Organic anolyte materials for redox flow batteries and redox flow batteries containing organic anolyte materials are disclosed. |
| FILED | Wednesday, June 08, 2016 |
| APPL NO | 15/580048 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 213/51 (20130101) C07D 213/55 (20130101) C07D 213/56 (20130101) C07D 213/89 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/368 (20130101) H01M 4/9008 (20130101) H01M 8/188 (20130101) Original (OR) Class H01M 10/0567 (20130101) H01M 10/0569 (20130101) H01M 50/40 (20210101) H01M 2300/0028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056731 | Biswas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FEASIBLE, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | FEASIBLE, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Shaurjo Biswas (El Cerrito, California); Robert Charles Mohr (Berkeley, California); Andrew Gaheem Hsieh (Berkeley, California); Barry James Van Tassell (El Cerrito, California); Daniel Artemis Steingart (Princeton, New Jersey); Jonathan Ajo-Franklin (Berkeley, California) |
| ABSTRACT | Systems and methods for battery testing including a holder system. The holder system is designed to couple one or more transducers to a battery under test, wherein the one or more transducers are configured for electrochemical-acoustic signal interrogation (EASI) of the battery. The holder system includes at least one arm to house at least one transducer to be coupled to the battery, and a pressure applying device to apply pressure to the at least one transducer, and to control pressure between the at least one transducer and the battery. The holder system is also configured to determine the pressure between the at least one transducer and the battery and adjust the pressure applied to the at least one transducer based on the determined pressure. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/817966 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/28 (20130101) G01N 29/223 (20130101) G01N 29/2462 (20130101) G01N 2291/048 (20130101) G01N 2291/106 (20130101) G01N 2291/2634 (20130101) G01N 2291/02863 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/5044 (20130101) H01M 6/5083 (20130101) H01M 10/48 (20130101) H01M 10/482 (20130101) H01M 10/486 (20130101) Original (OR) Class H01M 10/4257 (20130101) H01M 10/4285 (20130101) H01M 50/20 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057927 | Shepard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| ASSIGNEE(S) | Skylark WL Holdings, LLC (Houston, Texas) |
| INVENTOR(S) | Clayton W. Shepard (Houston, Texas); Lin Zhong (Houston, Texas); Abeer Javed (Houston, Texas); Hang Yu (Houston, Texas) |
| ABSTRACT | Disclosed embodiments include methods for control channel design in many-antenna multi-user (MU) multiple-input multiple-output (MIMO) wireless systems. A beacon comprising an identifier of a many-antenna base station is encoded into a base sequence. A plurality of synchronization sequences is generated based on the encoded base sequence and a set of orthogonal beam sequences. The many-antenna base-station transmits, using a plurality of antennas, the plurality of synchronization sequences in a plurality of beam directions associated with the set of orthogonal beam sequences for synchronization and associated with users without knowledge of channel state information (CSI). |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572577 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/046 (20130101) H04B 7/0417 (20130101) H04B 7/0452 (20130101) H04B 7/0456 (20130101) H04B 7/0617 (20130101) H04B 7/0695 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0053 (20130101) H04L 27/2613 (20130101) H04L 27/2692 (20130101) Wireless Communication Networks H04W 48/00 (20130101) H04W 56/001 (20130101) H04W 68/02 (20130101) H04W 72/14 (20130101) Original (OR) Class H04W 72/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11057991 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Rak-Hwan Kim (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Wakefield, Massachusetts) |
| ABSTRACT | Described herein are flexible and stretchable LED arrays and methods utilizing flexible and stretchable LED arrays. Assembly of flexible LED arrays alongside flexible plasmonic crystals is useful for construction of fluid monitors, permitting sensitive detection of fluid refractive index and composition. Co-integration of flexible LED arrays with flexible photodetector arrays is useful for construction of flexible proximity sensors. Application of stretchable LED arrays onto flexible threads as light emitting sutures provides novel means for performing radiation therapy on wounds. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 15/942242 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/287 (20210101) A61B 5/6806 (20130101) A61B 5/6867 (20130101) A61B 5/6883 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0257 (20130101) A61B 2562/0271 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/18 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3121 (20130101) H01L 23/3192 (20130101) H01L 27/1218 (20130101) H01L 29/7869 (20130101) H01L 29/78603 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/3011 (20130101) H01L 2924/3025 (20130101) H01L 2924/09701 (20130101) H01L 2924/12044 (20130101) H01L 2924/19041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/147 (20130101) H05K 1/0283 (20130101) Original (OR) Class H05K 3/323 (20130101) H05K 2201/09263 (20130101) H05K 2201/10106 (20130101) H05K 2203/1316 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49128 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11052458 | Bird et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Richard Keith Bird (Grafton, Virginia); Joel A. Alexa (Hampton, Virginia); Peter L. Messick (Poquoson, Virginia); Marcia S. Domack (Carrollton, Virginia); John A. Wagner (Newport News, Virginia) |
| ABSTRACT | Various embodiments provide methods in which a metal matrix composite (MMC) material is incorporated into a metallic structure during a one-step near-net-shape structural forming process. Various embodiments provide in-situ selective reinforcement processes in which the MMC may be pre-placed on a forming tool in locations that correspond to specific regions in the metallic structure. Various embodiment near-net-shape structural forming processes may then be executed and result in various embodiment metallic structural components with selectively-reinforced regions that provide enhanced mechanical properties in key locations. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/040528 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/16 (20130101) B21D 26/059 (20130101) B21D 35/007 (20130101) B21D 37/01 (20130101) B21D 49/00 (20130101) Making Forged or Pressed Metal Products, e.g Horse-shoes, Rivets, Bolts or Wheels B21K 25/00 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 13/00 (20130101) B22D 19/02 (20130101) Original (OR) Class B22D 19/14 (20130101) B22D 21/007 (20130101) B22D 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11052989 | Livieratos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Evangelos Livieratos (Manassas, Virginia); Cory Kays (Manassas, Virginia) |
| ABSTRACT | A wing-twist aircraft having a wing, an actuation system, a sensor, and/or a controller. The wing may have a wingspan that extends to a wing tip. The wing may further include a spar aligned in a span-wise direction, wherein at least one rib is operatively coupled to the spar. The actuation system may be configured to torsionally rotate the spar, which, in turn, torsionally rotates (pivots) the at least one rib coupled to the spar, thereby twisting the wing. The sensor may be configured to measure a characteristic of the wing, while the controller may be configured to command the actuation system to torsionally rotate the spar based at least in part on input from the sensor. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/701943 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/52 (20130101) Original (OR) Class B64C 9/10 (20130101) B64C 39/10 (20130101) B64C 2039/105 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053009 | McCarley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Michael C. McCarley (Titusville, Florida); Christopher Ferguson (Cape Canaveral, Florida) |
| ABSTRACT | A conformal seat insert for an adjustable vehicle seat, the conformal seat insert comprising an insert frame, the insert frame having one or more insert reference features for locating the insert frame on a seat frame of the vehicle seat in a predetermined position relative to the seat frame, and a contoured support surface formed in the insert frame, the contoured support surface having a crew reference point corresponding to an acromial point of a shoulder of a seat occupant of the adjustable vehicle seat, the crew reference point being a datum from which an eye position of the seat occupant is established relative to instrumentation of an aerospace vehicle in which the adjustable vehicle seat is located. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 16/593366 |
| ART UNIT | 3636 — Static Structures, Supports and Furniture |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/771 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for B60N 2/24 (20130101) B60N 2/643 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 11/062 (20141201) B64D 11/064 (20141201) B64D 11/0642 (20141201) B64D 11/0689 (20130101) Original (OR) Class Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) B64G 1/62 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/35134 (20130101) G05B 2219/49007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053030 | Weathers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Weathers (Huntsville, Alabama); Kraig A. Behel (Athens, Alabama); Mark W. Ullom (Huntsville, Alabama) |
| ABSTRACT | A load-decoupling attachment system is configured to secure a component to a primary structure. The load-decoupling system includes a fore end coupling bracket that is configured to attach to a fore end of the component. A first tie rod is coupled to the fore end coupling bracket. The first tie rod is configured to couple to a first portion of the primary structure. A second tie rod is coupled to the fore end coupling bracket. The second tie rod configured to couple to a second portion of the primary structure. A universal joint mount assembly is configured to couple to an aft end of the component and a third portion of the primary structure. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/154817 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/40 (20130101) B64G 1/641 (20130101) Original (OR) Class Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053169 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POWDERMET, INC. (Euclid, Ohio) |
| ASSIGNEE(S) | Powdermet, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257187 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/58 (20130101) C04B 35/515 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0645 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) C04B 2235/77 (20130101) C04B 2235/483 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/32 (20130101) C08J 9/35 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/24 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053962 | Corke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Thomas C. Corke (Granger, Indiana); Flint O. Thomas (Granger, Indiana) |
| ABSTRACT | A plasma plate is used to minimize drag of a fluid flow over an exposed surface. The plasma plate includes a series of plasma actuators positioned on the surface. Each plasma actuator is made of a dielectric separating a first electrode exposed to a fluid flow and a second electrode separated from the fluid flow under the dielectric. A pulsed direct current power supply provides a first voltage to the first electrode and a second voltage to the second electrode. The series of plasma actuators is operably connected to a bus which distribute powers and is positioned to minimize flow disturbances. The plasma actuators are arranged into a series of linear rows such that a velocity component is imparted to the fluid flow. |
| FILED | Friday, December 27, 2019 |
| APPL NO | 16/728924 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 23/005 (20130101) B64C 2230/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/172 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/12 (20130101) Original (OR) Class F15D 1/0075 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) H05H 2001/2412 (20130101) H05H 2001/2437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11051490 | Morales Ramos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Juan A. Morales Ramos (Greenville, Mississippi); Scott L. Lee (Cleveland, Mississippi); Maria G. Rojas (Greenville, Mississippi) |
| ABSTRACT | The insect water supply system is configured to prevent the insects (such as crickets) from self-contaminating the water supplied to the insects' rearing enclosure. The system is designed so that the insects drink in an inverted (i.e. upside down) and elevated position—consequently the insects' feces fall downward toward the ground and away from their water source—and therefore do not contaminate the insects' water supply. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/935403 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 7/00 (20130101) Original (OR) Class A01K 67/033 (20130101) A01K 2227/706 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053513 | Pandey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald Danforth Plant Science Center (St. Louis, Missouri) |
| ASSIGNEE(S) | Donald Danforth Plant Science Center (St Louis, Missouri) |
| INVENTOR(S) | Sona Pandey (St. Louis, Missouri); Swarup Roy Choudhry (St. Louis, Missouri) |
| ABSTRACT | Provided are plants that express, or overexpress, type III Gγ protein AGG3. Such plants exhibit faster vegetative and reproductive growth, accompanied by an increase in photosynthetic efficiency. Constitutive or seed-specific expression of AGG3 in Camelina increases seed size, seed mass, and seed number per plant by 15-40%, effectively resulting in significantly higher oil yield per plant. AGG3-expressing Camelina plants also exhibit improved stress tolerance. Use of AGG3 is therefore an effective biotechnological tool to dramatically increase stress tolerance and plant yield, including oil, in agricultural and horticultural crops. |
| FILED | Tuesday, July 15, 2014 |
| APPL NO | 14/905394 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) C12N 15/8261 (20130101) C12N 15/8271 (20130101) C12N 15/8273 (20130101) C12N 15/8274 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054368 | Gold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kaitlin M. Gold (Madison, Wisconsin); Amanda J. Gevens (McFarland, Wisconsin); Philip A. Townsend (Madison, Wisconsin) |
| ABSTRACT | The present inventors have recognized that various diseases in plants, such as Phytophthora infestans (late blight) and Alternaria solani (early blight), and/or various stages of such diseases in plants, can be reliably detected by applying measurements from electromagnetic reflections detected from a plant in a model to produce an output indicating a probability of the disease and/or stage. In one aspect, coefficients can be applied to each measurement at each wavelength to emphasize identification of a given disease or stage. In another aspect, an imager can capture images comprising spectral pixels in which each pixel comprises measurements from the electromagnetic reflections for application in a model to identify a given disease or stage. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/251415 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Soil Working in Agriculture or Forestry; Parts, Details, or Accessories of Agricultural Machines or Implements, in General A01B 79/005 (20130101) Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 33/0098 (20130101) G01N 2021/635 (20130101) G01N 2021/8466 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11053135 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aegis Technology Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Aegis Technology Inc. (Santa Ana, California) |
| INVENTOR(S) | Qi Chen (Santa Ana, California); Zhigang Lin (Santa Ana, California) |
| ABSTRACT | Producing CoxFe100-x, where x is an integer from 20 to 95, nanoparticles by: (a) providing a first aqueous hydroxide solution; (b) preparing a second aqueous solution containing iron ions and cobalt ions; and (c) depositing measured volumes of the second aqueous solution into the first aqueous solution whereby coprecipitation yields CoFe alloy nanoparticles, wherein step (c) occurs in an essentially oxygen-free environment. The nanoparticles are annealed at ambient temperatures to yield soft nanoparticles with targeted particle size, saturation magnetization and coercivity. The chemical composition, crystal structure and homogeneity are controlled at the atomic level. The CoFe magnetic nanoparticles have Ms of 200-235 emu/g, (Hc) coercivity of 18 to 36 Oe and size range of 5-40 nm. The high magnetic moment CoFe nanoparticles can be employed in drug delivery, superior contrast agents for highly sensitive magnetic resonance imaging, magnetic immunoassay, magnetic labeling, waste water treatment, and magnetic separation. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 16/403468 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0009 (20130101) C01G 51/003 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/04 (20130101) C01P 2004/64 (20130101) C01P 2006/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053169 | Doud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POWDERMET, INC. (Euclid, Ohio) |
| ASSIGNEE(S) | Powdermet, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Brian P. Doud (Cleveland Heights, Ohio); Mark V. Grogan (Cleveland, Ohio); Andrew Sherman (Mentor, Ohio) |
| ABSTRACT | A thermally-insulating composite material with co-shrinkage in the form of an insulating material formed by the inclusion of microballoons in a matrix material such that the microballoons and the matrix material exhibit co-shrinkage upon processing. The thermally-insulating composite material can be formed by a variety of microballoon-matrix material combinations such as polymer microballoons in a preceramic matrix material. The matrix materials generally contain fine rigid fillers. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257187 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 35/58 (20130101) C04B 35/515 (20130101) C04B 35/515 (20130101) C04B 35/524 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/007 (20130101) Original (OR) Class C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/08 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0645 (20130101) C04B 38/0645 (20130101) C04B 2111/28 (20130101) C04B 2235/77 (20130101) C04B 2235/483 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3821 (20130101) C04B 2235/3826 (20130101) C04B 2235/5436 (20130101) C04B 2235/9607 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/32 (20130101) C08J 9/35 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/24 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) F16L 59/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056731 | Biswas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FEASIBLE, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | FEASIBLE, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Shaurjo Biswas (El Cerrito, California); Robert Charles Mohr (Berkeley, California); Andrew Gaheem Hsieh (Berkeley, California); Barry James Van Tassell (El Cerrito, California); Daniel Artemis Steingart (Princeton, New Jersey); Jonathan Ajo-Franklin (Berkeley, California) |
| ABSTRACT | Systems and methods for battery testing including a holder system. The holder system is designed to couple one or more transducers to a battery under test, wherein the one or more transducers are configured for electrochemical-acoustic signal interrogation (EASI) of the battery. The holder system includes at least one arm to house at least one transducer to be coupled to the battery, and a pressure applying device to apply pressure to the at least one transducer, and to control pressure between the at least one transducer and the battery. The holder system is also configured to determine the pressure between the at least one transducer and the battery and adjust the pressure applied to the at least one transducer based on the determined pressure. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/817966 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/28 (20130101) G01N 29/223 (20130101) G01N 29/2462 (20130101) G01N 2291/048 (20130101) G01N 2291/106 (20130101) G01N 2291/2634 (20130101) G01N 2291/02863 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/5044 (20130101) H01M 6/5083 (20130101) H01M 10/48 (20130101) H01M 10/482 (20130101) H01M 10/486 (20130101) Original (OR) Class H01M 10/4257 (20130101) H01M 10/4285 (20130101) H01M 50/20 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11052501 | Midyette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark Midyette (Elizabeth City, North Carolina); Craig Deen (Elizabeth City, North Carolina); Harlon Parchment (Elizabeth City, North Carolina) |
| ABSTRACT | In one example, an on-wing apparatus for in-situ cutting on a wing-to-fuselage attachment includes a first linear bearing disposed on a first mount plate to move in a first direction. A second linear bearing is disposed on a second mount plate to move in a second direction. The second mount plate is attached to the first linear bearing. A tool mounting member is attached to the second linear bearing. A cutter is attached to the tool mounting member to be adjustable, relative to the second linear bearing, in a rotational direction around an adjustment axis. One of the first direction and the second direction is a depth direction of the cut parallel to the adjustment axis, and the other is a length direction of the cut. A width position of the cut is determined by rotational adjustment of the cutter with respect to the second linear bearing in the rotational direction. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934645 |
| ART UNIT | 3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Milling B23C 3/10 (20130101) B23C 3/36 (20130101) B23C 2215/04 (20130101) Details, Components, or Accessories for Machine Tools, e.g Arrangements for Copying or Controlling; Machine Tools in General Characterised by the Construction of Particular Details or Components; Combinations or Associations of Metal-working Machines, Not Directed to a Particular Result B23Q 9/0007 (20130101) Original (OR) Class B23Q 9/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11054517 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Peter Roland Smith (Westfield, New Jersey); James Christopher Weatherall (Linwood, New Jersey); Jeffrey Brian Barber (Vineland, New Jersey); Barry Thomas Smith (Egg Harbor, New Jersey) |
| ABSTRACT | The present disclosure is directed to a measurement system for measuring a reflection coefficient of a test sample, including: a transceiver antenna configured to be coupled to a source of electromagnetic radiation; and a RAM positioned between the transceiver antenna and a measurement region of the transceiver antenna, wherein the RAM comprises an aperture substantially orthogonal to and substantially aligned with a transceiving axis of the transceiver antenna. A method for obtaining error correction of a measurement system and a method of measuring a reflection coefficient in a test sample are also provided. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 16/929751 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/40 (20130101) G01S 7/411 (20130101) G01S 13/88 (20130101) G01S 13/0209 (20130101) G01S 13/887 (20130101) Original (OR) Class G01S 2007/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11052090 | Schinazi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); CHILDREN'S HEALTHCARE OF ATLANTA, INC. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Raymond F. Schinazi (Miami, Florida); Christina Gavegnano (Decatur, Georgia) |
| ABSTRACT | Compounds, compositions, and methods of treatment and prevention of HIV, including HIV-1 and HIV-2, Dengue, and Chikungunya infection are disclosed. The compounds are TREM-1 inhibitors. Combinations of these TREM-1 inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, JAK inhibitors, macrophage depleting agents, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of HIV, Dengue, or Chikungunya virus in an infected patient. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/788374 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/10 (20130101) A61K 38/17 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/18 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11053290 | Ashkar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); The United States Government as Represented by the Department of Veterans Affair (Washington D.C., District of Columbia) |
| INVENTOR(S) | Tarek Maurice Ashkar (Zionsville, Indiana); Radmila Micanovic (Indianapolis, Indiana) |
| ABSTRACT | Embodiments of the present disclosure provide polypeptides, related materials and compositions, and methods for their use. In certain embodiments, the present disclosure provides a monomeric Tamm-Horsfall Protein polypeptide, or a biologically active truncation thereof. Other embodiments provide polynucleotides encoding a polypeptide described herein, nucleic acid expression vectors including the polynucleotides, and recombinant host cells including the expression vector. Yet other embodiments provide pharmaceutical compositions including a polypeptide described herein. Also provided are methods for treating a renal disease, disorder, or condition in a subject and/or modulating an immune response in a subject. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/771036 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 35/22 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/435 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 11055351 | Shyu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chi-Ren Shyu (Columbia, Missouri); Michael Phinney (Columbia, Missouri) |
| ABSTRACT | The present disclosure relates to a persistent data structure employed as a tree structure with a frequent pattern mining paradigm. The number of nodes in the tree structure scales linearly with respect to the number unique items within the itemsets associated with the nodes. With the disclosed pattern mining paradigm, compressed representations of maximal patterns may be mined with the goal of detecting a frequent maximal pattern covers in a top down approach. Thus, large patterns are detected before their subsets yielding a significant reduction in computation time. The persistent data structure is a dynamic data structure which may be updated to add or delete nodes or transactional information without the need for recreating the entire tree structure. Furthermore, the persistent data structure may be run by a computing system either locally or on a parallelized distributed computing architecture to increase operational performance. |
| FILED | Tuesday, April 17, 2018 |
| APPL NO | 15/955462 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) G06F 16/2246 (20190101) G06F 16/2379 (20190101) G06F 16/2465 (20190101) G06F 16/9027 (20190101) Original (OR) Class G06F 2216/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11054318 | Hassan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana); University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana); University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Waled T. Hassan (Indianapolis, Indiana); Peter B. Nagy (Cincinnati, Ohio) |
| ABSTRACT | A system may include a first injection electrode, a second injection electrode, a first sensing coil, and a second sensing coil. The first injection electrode and the second electrode may each be configured to contact a material and conduct an alternating current through a portion of the material. The first sensing coil and a second sensing coil may each be configured to inductively sense a Hall current created by the alternating current and a magnetic field perpendicular to the alternating current. The first sensing coil and the second sensing coil may be coupled in series. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919993 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/127 (20130101) Original (OR) Class G01L 5/0047 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/005 (20130101) G01M 5/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/82 (20130101) G01N 27/90 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 15/18 (20130101) G01R 19/10 (20130101) G01R 27/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11055232 | Keppel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | David Pardo Keppel (Mountain View, California); Binh Pham (Burlingame, California) |
| ABSTRACT | A processor includes a translation lookaside buffer (TLB) to store a TLB entry, wherein the TLB entry comprises a first set of valid bits to identify if the first TLB entry corresponds to a virtual address from a memory access request, wherein the valid bits are set based on a first page size associated with the TLB entry from a first set of different page sizes assigned to a first probe group; and a control circuit to probe the TLB for each page size of the first set of different page sizes assigned to the first probe group in a single probe cycle to determine if the TLB entry corresponds to the virtual address from the memory access request. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370848 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1009 (20130101) G06F 12/1036 (20130101) Original (OR) Class G06F 12/1045 (20130101) G06F 2212/657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11054590 | Wan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Noel Wan (Cambridge, Massachusetts); Jacques Johannes Carolan (Cambridge, Massachusetts); Tsung-Ju Lu (Cambridge, Massachusetts); Ian Robert Christen (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A process is provided for the high-yield heterogeneous integration of ‘quantum micro-chiplets’ (QMCs, diamond waveguide arrays containing highly coherent color centers) with an aluminum nitride (AlN) photonic integrated circuit (PIC). As an example, the process is useful for the development of a 72-channel defect-free array of germanium-vacancy (GeV) and silicon-vacancy (SiV) color centers in a PIC. Photoluminescence spectroscopy reveals long-term stable and narrow average optical linewidths of 54 MHz (146 MHz) for GeV (SiV) emitters, close to the lifetime-limited linewidth of 32 MHz (93 MHz). Additionally, inhomogeneities in the individual qubits can be compensated in situ with integrated tuning of the optical frequencies over 100 GHz. The ability to assemble large numbers of nearly indistinguishable artificial atoms into phase-stable PICs is useful for development of multiplexed quantum repeaters and general-purpose quantum computers. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/734727 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11055653 | Bornitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Carrie Ann Bornitz (Sioux Falls, South Dakota); Robert E. Dixon, Jr. (Haymarket, Virginia); Ryan M. Luckay (Vienna, Virginia) |
| ABSTRACT | Systems and methods of creating, managing, and distributing supplemental content associated with items in a distribution network. A physical delivery item can be imaged and associated with additional content generated or associated with the sender of the physical delivery item. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/912360 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11053858 | McGrath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Rachel A. McGrath (Hartford, Connecticut); William N. Green (East Hartford, Connecticut) |
| ABSTRACT | A gas turbine engine includes a shaft compartment containing at least one main shaft which rotates about a main axis of rotation; and a tower shaft engaged with the at least one main shaft for rotation about a tower shaft axis of rotation, the tower shaft being mounted in a bearing compartment extending away from the shaft compartment, wherein the bearing compartment is sealed against leakage from inside the bearing compartment to ambient. The seal can be produced using a tower shaft seal held in a seal housing and sealing against one or more faces of the tower shaft assembly or components. |
| FILED | Thursday, February 07, 2019 |
| APPL NO | 16/269686 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/50 (20130101) F05D 2240/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11055872 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Yang Chen (Westlake Village, California); Deepak Khosla (Camarillo, California); Ryan M. Uhlenbrock (Calabasas, California) |
| ABSTRACT | Described is a system for real-time object recognition. The system extracts a candidate target region representing a candidate object from an input image of a scene based on agglomeration of channel features. The candidate target region is classified using a trained convolutional neural network (CNN) classifier, resulting in an initial classified object. A multi-target tracker is used for tracking the classified objects for final classification of each classified object, resulting in a final output, and a device is controlled based on the final output. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883822 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) Original (OR) Class G06T 7/246 (20170101) G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11056797 | Rommel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eagle Technology, LLC (Melbourne, Florida) |
| ASSIGNEE(S) | EAGLE TECHNOLOGY, LLC (Melbourne, Florida) |
| INVENTOR(S) | Monica Rommel (Savage, Minnesota); Rodney Sorrell (Melbourne, Florida); David Norton (Rockledge, Florida); Maria R. Parkhurst (Melbourne, Florida) |
| ABSTRACT | An antenna reflector comprising a mesh material formed of a Carbon Nano-Tube (“CNT”) yarn that is reflective of radio waves and has a low solar absorptivity to hemispherical emissivity ratio (αsolar/εH ratio) and a low Coefficient of Thermal Expansion (“CTE”). |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524698 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Knitting D04B 1/14 (20130101) D04B 21/12 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Antennas, i.e Radio Aerials H01Q 15/16 (20130101) Original (OR) Class H01Q 15/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 06, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page