FedInvent™ Patents
Patent Details for Tuesday, August 03, 2021
This page was updated on Tuesday, August 03, 2021 at 03:45 PM GMT
Department of Health and Human Services (HHS)
| US 11076593 | Deckelbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Richard J. Deckelbaum (Hastings on Hudson, New York); Ravichandran Ramasamy (Ardsley, New York) |
| ABSTRACT | It has been discovered that isolated organs and tissues perfused/reperfused in perfusion buffer to which omega-3 glyceride oil had been added retain higher levels of function than if perfused/reperfused without the omega-3 glycerides. Isolated hearts reperfused ex vivo after induced ischemia in n-3 triglyceride perfusion emulsion maintained a normal heart rate and normal LVDP and showed a dramatically reduced frequency of arrhythmias compared to control hearts. Further, test hearts reperfused with n-3 oil triglyceride emulsion showed a decrease in creatine kinase and upregulation of certain beneficial proteins including the anti-apoptotic gene marker Bcl-2. |
| FILED | Monday, August 27, 2018 |
| APPL NO | 16/113407 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11076762 | Vaschillo et al. |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Evgeny G. Vaschillo (Edison, New Jersey); Bronya Vaschillo (Edison, New Jersey) |
| ABSTRACT | Methods and systems for express estimation of the arterial elasticity in a subject are presented. The methods and systems provide simplicity in measurement and the opportunity to measure the arterial elasticity through HRV. The method includes imposing a rhythmical stimulation at a frequency between about 0.06 Hz and 0.081 Hz to cause an oscillation on the cardiovascular system of a subject. The method further include measuring a response associated with the oscillation on the cardiovascular system and determining the arterial elasticity of the subject based on a level of the response associated with the oscillation. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919757 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0205 (20130101) A61B 5/352 (20210101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/02108 (20130101) A61B 5/02225 (20130101) A61B 5/02255 (20130101) A61B 5/7246 (20130101) A61B 5/7257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11076784 | Mycek et al. |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mary-Ann Mycek (Ann Arbor, Michigan); Fan Wu (Greenbelt, Maryland); James M. Scheiman (Charlottesville, Virginia); Euisik Yoon (Ypsilanti, Michigan); William Lloyd (Farmington Hills, Michigan); Seung Yup Lee (Decatur, Georgia) |
| ABSTRACT | A system for analyzing tissue includes a platform and an optical sensing unit coupled to the platform. The optical sensing unit has a detector and a plurality of light sources surrounding and electrically isolated from the detector. The optical sensing units obtain optical data for tissue analysis. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/706900 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0084 (20130101) A61B 5/0261 (20130101) A61B 5/1455 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) Image Data Processing or Generation, in General G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11076821 | Boone et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John M. Boone (Fair Oaks, California); Andrew M. Hernandez (Nevada City, California); Peymon Gazi (Berkeley, California) |
| ABSTRACT | A size and/or shape specific 3D-beam modulation filter and a size and/or shape specific immobilizer are provided for cone-beam breast computed tomography (bCT). The immobilizer places the breast on an optimal position in the field of view of the scanner system and the 3D-beam modulation filter modulates the incident x-ray beam in the cone-angle (i.e. z-axis of the detector panel) and fan angle (i.e. x-axis of the detector panel) directions in order to improve equalization of the photon fluence incident upon the detector panel and reduce unnecessary radiation dose that the breast receives. Both the immobilizer and the 3D-beam modulation filter are selected among a plurality of alternatives based on the specific shape, size and/or shape or size of the person's breast. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/779342 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/405 (20130101) A61B 6/0435 (20130101) A61B 6/502 (20130101) A61B 6/544 (20130101) A61B 6/582 (20130101) A61B 6/583 (20130101) A61B 6/4035 (20130101) A61B 6/4078 (20130101) A61B 6/4085 (20130101) Original (OR) Class A61B 6/5205 (20130101) A61B 6/5258 (20130101) A61B 6/5294 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11076836 | Ebbini et al. |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Emad S. Ebbini (Edina, Minnesota); Andrew J. Casper (Eau Claire, Wisconsin); Dalong Liu (Saint Paul, Minnesota); John R. Ballard (Saint Bonifacius, Minnesota) |
| ABSTRACT | A dual-mode ultrasound system provides real-time imaging and therapy delivery using the same transducer elements of a transducer array. The system may use a multi-channel driver to drive the elements of the array. The system uses a real-time monitoring and feedback image control of the therapy based on imaging data acquired using the dual-mode ultrasound array (DMUA) of transducer elements. Further, for example, multi-modal coded excitation may be used in both imaging and therapy modes. Still further, for example, adaptive, real-time refocusing for improved imaging and therapy can be achieved using, for example, array directivity vectors obtained from DMUA pulse-echo data. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262138 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/00 (20130101) A61B 8/08 (20130101) A61B 8/14 (20130101) A61B 8/54 (20130101) Original (OR) Class A61B 8/485 (20130101) A61B 8/0816 (20130101) A61B 8/0891 (20130101) A61B 8/4438 (20130101) A61B 8/4488 (20130101) A61B 8/5207 (20130101) A61B 8/5223 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) A61N 2007/027 (20130101) A61N 2007/0052 (20130101) A61N 2007/0095 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/5202 (20130101) G01S 7/52046 (20130101) G01S 15/8915 (20130101) G01S 15/8952 (20130101) G01S 15/8959 (20130101) G01S 15/8997 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077056 | Bellinger et al. |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew Bellinger (Wellesley, Massachusetts); Shiyi Zhang (Shanghai, China PRC); Carlo Giovanni Traverso (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts); Stacy Mo (Darien, Illinois); Tyler Grant (Arlington, Massachusetts); Mousa Jafari (Waltham, Massachusetts); Dean Liang Glettig (Cambridge, Massachusetts); Angela DiCiccio (San Francisco, California); Lowell L. Wood, Jr. (Bellevue, Washington); Philip A. Eckhoff (Kirkland, Washington) |
| ABSTRACT | Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance (e.g., a therapeutic agent), and, optionally, a linker. In some such embodiments, the linker may be configured to degrade such that the residence structure breaks apart and is released from the location internally of the subject after a predetermined amount of time. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/126786 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 9/0065 (20130101) Original (OR) Class A61K 31/65 (20130101) A61K 31/357 (20130101) A61K 31/7048 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/40 (20130101) A61K 47/42 (20130101) A61K 47/58 (20170801) A61K 47/6901 (20170801) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/4277 (20130101) C08G 63/08 (20130101) C08G 83/006 (20130101) C08G 2230/00 (20130101) Compositions of Macromolecular Compounds C08L 33/02 (20130101) C08L 33/08 (20130101) C08L 33/14 (20130101) C08L 2203/02 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077057 | Chipre et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Anthony J. Chipre (Rochester, New York); SonBinh T. Nguyen (Evanston, Illinois) |
| ABSTRACT | Provided herein are small unilamellar vesicles with surface-displayed polymer moieties, and methods of use and manufacture thereof. In particular, provided herein are polymer-grafted nanobins, and methods of drug delivery therewith. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738473 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Y10S 977/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077105 | Mohsen et al. |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Al-Walid A. Mohsen (Gibsonia, Pennsylvania); Gerard Vockley (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods of treating mitochondrial fatty acid b-oxidation and/or transport disorders arising from mutant proteins in the mitochondrial fatty acid β-oxidation and transport metabolic pathways in patients are provided. The methods modulate the mitochondrial fatty acid β-oxidation pathway at the last step so that the product of the mutant protein accumulates and stabilizes the mutant protein and/or the substrate(s)/product(s) of the down stream reactions accumulate and possibly bind to allosteric sites on the mutant protein to stabilize it. Trimetazidine pharmacodynamics function as such in the β-oxidation pathway. Further, a synergistic effect is observed where trimetazidine and PPARδ agonist combination enhanced enzyme activity and presence significantly more than either alone. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 16/345757 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 38/45 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077120 | Ganesh et al. |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Thota Ganesh (Alpharetta, Georgia); Jianxiong Jiang (Memphis, Tennessee); Raymond Dingledine (Norcross, Georgia) |
| ABSTRACT | The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/686046 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4192 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077121 | Bellacosa et al. |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania); Institut Curie (Paris, France); Institut de Génétique et de Biologie Moléculaire et Cellulaire (Illkrich, France) |
| ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania); Institut Curie (Paris, France); Institut de Genetique et de Biologie Moleculaire et Cellulaire (Illkrich, France) |
| INVENTOR(S) | Alfonso Bellacosa (Philadelphia, Pennsylvania); Rossella Tricarico (Philadelphia, Pennsylvania); Tim Yen (Philadelphia, Pennsylvania); Vikram Bhattacharjee (Philadelphia, Pennsylvania); Pietro Mancuso (Philadelphia, Pennsylvania); Lionel Larue (Paris, France); Irwin Davidson (Illkrich, France) |
| ABSTRACT | The invention provides compositions, kits, and methods for inducing growth arrest, differentiation, or senescence of cancer cells that express thymine DNA glycosylase, and treating the cancer accordingly. The methods comprise inhibiting expression or biologic activity of thymine DNA glycosylase in cancer cells. Inhibition of thymine DNA glycosylase in cancer cells may induce the cells to revert to a healthy, non-cancerous phenotype and/or may induce the cells to senesce. Cancer cells include melanoma, lung, prostate, pancreatic, ovarian, brain, colon, recto-sigmoid colon, and breast cancer cells. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/084680 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/277 (20130101) A61K 31/353 (20130101) A61K 31/404 (20130101) A61K 31/473 (20130101) A61K 31/475 (20130101) A61K 31/495 (20130101) A61K 31/546 (20130101) A61K 31/609 (20130101) A61K 31/5575 (20130101) Original (OR) Class A61K 33/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/15043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077130 | Haynes et al. |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Barton F. Haynes (Durham, North Carolina); Sallie Permar (Durham, North Carolina); M. Anthony Moody (Durham, North Carolina); Feng Gao (Durham, North Carolina); Hua-Xin Liao (Durham, North Carolina); Georgia Tomaras (Durham, North Carolina); David C. Montefiori (Durham, North Carolina) |
| ABSTRACT | The invention provides compositions and methods to induce and boost antibody response, including but not limited to IgG responses binding to HIV-1 in a subject in need thereof, wherein the induced/boosted plasma level of the antibody responses, for example V3 and/or CD4 binding site antibody responses, is over a threshold level and is associated with reduced risk of maternal-to-child-transmission (MTCT) of HIV-1. |
| FILED | Friday, September 26, 2014 |
| APPL NO | 15/025031 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 39/21 (20130101) A61K 39/395 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) C12N 2770/00041 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077140 | Sadelain et al. |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Michel Sadelain (New York, New York); Matthias Stephan (Boston, Massachusetts) |
| ABSTRACT | The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen-recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/135678 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 39/0011 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 2501/25 (20130101) C12N 2501/51 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) C12N 2799/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077156 | O'Shea et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Clodagh O'Shea (San Diego, California); Shigeki Miyake-Stoner (La Jolla, California) |
| ABSTRACT | An adenovirus comprising an E1A polypeptide comprising one or more modifications and comprising an E4orf6/7 polypeptide comprising one or more modifications is described. Compositions and kits comprising the modified adenoviruses are also described. Further described is a method of treating a proliferative disorder in a subject comprising administering to the subject an adenovirus comprising the E1A polypeptide comprising one or more modifications and comprising the E4orf6/7 polypeptide comprising one or more modifications. |
| FILED | Monday, September 14, 2015 |
| APPL NO | 14/852981 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/761 (20130101) Original (OR) Class A61K 35/768 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/10021 (20130101) C12N 2710/10032 (20130101) C12N 2710/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077176 | Brenner |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | Malcolm K. Brenner (Bellaire, Texas) |
| ABSTRACT | Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively killed if the patient experiences dangerous side effects. Provided also within relates in part to methods for preventing or treating Graft versus Host Disease by modifying T cells before administration to a patient, so that they may be selectively killed if GvHD develops in the patient. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 15/886309 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 35/545 (20130101) A61K 38/52 (20130101) Original (OR) Class A61K 38/4873 (20130101) A61K 39/001 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0663 (20130101) C12N 2501/48 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 304/22062 (20130101) C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077178 | Perera et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Liyanage Parakrama Perera (Bethesda, Maryland); Thomas Alexander Waldmann (Bethesda, Maryland); Kevin Charles Conlon (Bethesda, Maryland); Pin-Yu Perera (Washington, District of Columbia) |
| ABSTRACT | A chimeric antigen receptor is disclosed that includes: (a) an scFv comprising a light chain variable domain (VL) and a heavy chain variable domain (VH), wherein the scFv specifically binds to CCR4; (b) a hinge and transmembrane domain from CD8; (c) an intracellular 4-1BB signaling domain; and (d) an intracellular CD3 zeta signaling domain, wherein (a)-(d) are in N to C terminal order. Uses of the chimeric antigen receptor, such as for treating a malignancy, are also disclosed. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 16/334724 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) A61K 31/7076 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2866 (20130101) C07K 2317/24 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077182 | Hinrichs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of Americans represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christian S. Hinrichs (Bethesda, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of preparing an isolated population of human papillomavirus (HPV)-specific T cells comprise dividing an HPV-positive tumor sample into multiple fragments; separately culturing the multiple fragments; obtaining T cells from the cultured multiple fragments; testing the T cells for specific autologous HPV-positive tumor recognition; selecting the T cells that exhibit specific autologous HPV-positive tumor recognition; and expanding the number of selected T cells to produce a population of HPV-specific T cells for adoptive cell therapy. Related methods of treating or preventing cancer using the T cells are also disclosed. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113570 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 7/00 (20130101) C12N 2501/2302 (20130101) C12N 2502/30 (20130101) C12N 2710/20011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077183 | Tang et al. |
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| FUNDED BY |
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| APPLICANT(S) | MicroVAX, LLC (Warrenton, Virginia) |
| ASSIGNEE(S) | MicroVAX, LLC (Warrenton, Virginia) |
| INVENTOR(S) | Yucheng Tang (San Diego, California); Albert B. Deisseroth (Potomac, Maryland) |
| ABSTRACT | Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 15/393543 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/53 (20130101) A61K 2039/55 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70575 (20130101) C07K 2319/02 (20130101) C07K 2319/06 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/20034 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077190 | Thyagarajan et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | Baskaran Thyagarajan (Laramie, Wyoming); Padmamalini Baskaran (Laramie, Wyoming) |
| ABSTRACT | A magnetic nanoparticle including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical can include a core region having a magnetic nanoparticle (MNPs) and a TRPV1 protein agonist. Further, an exterior coating comprising a polymer can be formed around the core region. The magnetically responsive pharmaceutical can be administered to a recipient and directed to a target region using an external magnetic field. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/543161 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/5031 (20130101) A61K 9/5094 (20130101) A61K 9/5153 (20130101) A61K 31/23 (20130101) A61K 31/165 (20130101) A61K 31/231 (20130101) A61K 31/357 (20130101) A61K 31/7034 (20130101) A61K 41/00 (20130101) Original (OR) Class A61K 41/0052 (20130101) A61K 47/02 (20130101) A61K 47/6941 (20170801) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077197 | Manoharan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arbutus Biopharma Corporation (Burnaby, Canada) |
| ASSIGNEE(S) | ARBUTUS BIOPHARMA CORPORATION (Burnaby, Canada) |
| INVENTOR(S) | Muthiah Manoharan (Cambridge, Massachusetts); Muthusamy Jayaraman (Cambridge, Massachusetts); Kallanthottathil G. Rajeev (Cambridge, Massachusetts); Laxman Eltepu (Cambridge, Massachusetts); Steven Ansell (Cambridge, Massachusetts); Jianxin Chen (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure XXXIII, wherein: R1 and R2 are each independently for each occurrence optionally substituted C10-C30 alkyl, optionally substituted C10-C30 alkenyl, optionally substituted C10-C30 alkynyl, optionally substituted C10-C30 acyl, or -linker-ligand; R3 is H, optionally substituted C1-C10 alkyl, optionally substituted C2-C10 alkenyl, optionally substituted C2-C10 alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, ω-aminoalkyls, ω-(substituted)aminoalkyls, ω-phosphoalkyls, ω-thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; and E is C(O)O or OC(O). |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 15/617520 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) A61K 47/10 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/28 (20130101) A61K 47/44 (20130101) Original (OR) Class A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) Acyclic or Carbocyclic Compounds C07C 229/08 (20130101) C07C 229/30 (20130101) C07C 237/16 (20130101) C07C 251/38 (20130101) C07C 251/78 (20130101) C07C 271/12 (20130101) C07C 271/20 (20130101) C07C 323/25 (20130101) Heterocyclic Compounds C07D 203/10 (20130101) C07D 317/28 (20130101) C07D 317/44 (20130101) C07D 317/46 (20130101) C07D 317/72 (20130101) C07D 319/06 (20130101) C07D 405/12 (20130101) C07D 491/056 (20130101) C07D 491/113 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077199 | Moynihan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kelly Dare Moynihan (Allston, Massachusetts); Rebecca Lynn Holden (Cambridge, Massachusetts); Darrell J. Irvine (Arlington, Massachusetts); Bradley Lether Pentelute (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/059523 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) A61K 39/001192 (20180801) A61K 47/646 (20170801) Original (OR) Class A61K 2039/876 (20180801) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/76 (20130101) C07K 14/4748 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077201 | Govindan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); Sung-Ju Moon (New Providence, New Jersey); David M. Goldenberg (Delray Beach, Florida) |
| ABSTRACT | The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 16/733816 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6841 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 47/6855 (20170801) A61K 47/6857 (20170801) A61K 47/6861 (20170801) A61K 47/6889 (20170801) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 491/22 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/1063 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 16/3046 (20130101) C07K 16/3076 (20130101) C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/40 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/94 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077210 | Frangioni et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts); Georgia State University Research Foundation Inc. (, None) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts); Georgia State University Research Foundation Inc. (Atlanta, Georgia) |
| INVENTOR(S) | John V. Frangioni (Wayland, Massachusetts); Hak Soo Choi (Needham, Massachusetts); Maged M. Henary (Atlanta, Georgia) |
| ABSTRACT | The instant invention provides near-infrared fluorescent biological contrast agents and methods of using them. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 15/033337 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/003 (20130101) A61K 49/0017 (20130101) A61K 49/0021 (20130101) Original (OR) Class A61K 49/0028 (20130101) A61K 49/0032 (20130101) A61K 49/0041 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 17/00 (20130101) C09B 19/00 (20130101) C09B 23/04 (20130101) C09B 23/0016 (20130101) C09B 23/0025 (20130101) C09B 23/0033 (20130101) C09B 23/0041 (20130101) C09B 23/0066 (20130101) C09B 23/083 (20130101) C09B 23/086 (20130101) C09B 57/10 (20130101) C09B 69/008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077212 | Morse et al. |
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| FUNDED BY |
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| APPLICANT(S) | David L. Morse (Tampa, Florida); Robert J. Gillies (Tampa, Florida); William Bradford Carter (Tampa, Florida); Narges K. Tafreshi (Tampa, Florida); Marilyn M. Bui (Tampa, Florida); Steven A. Enkemann (Lutz, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | David L. Morse (Tampa, Florida); Robert J. Gillies (Tampa, Florida); William Bradford Carter (Tampa, Florida); Narges K. Tafreshi (Tampa, Florida); Marilyn M. Bui (Tampa, Florida); Steven A. Enkemann (Lutz, Florida) |
| ABSTRACT | Cellular targets on cancer cells have been identified that can be used with targeted molecular imaging to detect the cancer cells in vivo. Non-invasive methods for detecting cancer cells, such as metastasized cancer cells, are therefore provided. Also provided are compositions and kits for use in the disclosed methods. |
| FILED | Wednesday, August 24, 2011 |
| APPL NO | 13/813605 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0058 (20130101) Original (OR) Class A61K 51/1045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077213 | Bawendi et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi G. Bawendi (Cambridge, Massachusetts); Daniel K. Harris (Wilton, Connecticut); Oliver T. Bruns (Boston, Massachusetts); Thomas S. Bischof (Medford, Massachusetts) |
| ABSTRACT | InAs based core-shell particles which leads to tunable, narrow emitting semiconductor nanocrystals with a very high quantum yield which can be preserved in physiological buffers with long stability can used for short wavelength infrared (SWIR) imaging. Increased resolution with reduced read time and increased imaging frequency can provide advantages in in vivo applications. |
| FILED | Tuesday, April 22, 2014 |
| APPL NO | 14/258681 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/489 (20130101) A61B 5/02007 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0067 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/565 (20130101) C09K 11/883 (20130101) C09K 11/7492 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/40 (20130101) C30B 29/60 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/83 (20130101) Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077421 | Srinivas et al. |
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| FUNDED BY |
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| APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Steven Dietz (Englewood, Colorado) |
| ABSTRACT | The present invention relates to a carbon sorbent the can selectively remove platinum-group metals and other heavy metals such as tin without co-removing organic synthesis products including pharmaceutical intermediates and finished Active Pharmaceutical Ingredients (APIs). The carbon sorbents of the present invention are made from low-cost, high purity starting materials and the resulting carbon sorbents are also very pure. The carbon sorbents possess a combination of certain nitrogen and phosphorous groups combined with mesoporosity (2 to 50 nm diameter pores) that proves the high metal adsorption. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 16/128293 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 15/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) Original (OR) Class B01J 20/305 (20130101) B01J 20/3078 (20130101) B01J 20/28057 (20130101) B01J 20/28061 (20130101) B01J 20/28064 (20130101) B01J 20/28066 (20130101) B01J 20/28069 (20130101) B01J 20/28071 (20130101) B01J 20/28083 (20130101) B01J 2220/4825 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/30 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/80 (20130101) Acyclic or Carbocyclic Compounds C07C 67/34 (20130101) C07C 67/56 (20130101) C07C 201/12 (20130101) C07C 201/16 (20130101) Heterocyclic Compounds C07D 209/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078153 | Silverman |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois) |
| ABSTRACT | Disclosed are enantiomerically pure cyclopentane-based compounds that are prepared by a multiple-step synthesis process. The disclosed compounds have been designed to inhibit gamma-aminobutyric acid-amino transferase (GABA-AT) activity and ornithine aminotransferase (OAT) activity. Some of the enantiomerically pure compounds inhibit OAT activity more potently than the racemic compound. The disclosed compounds may be used to selectively inhibit OAT activity, for example, to treat hepatocellular carcinoma and/or used to selected inhibit GABA-AT activity, for example, to treat neurological diseases and disorders. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839441 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 229/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078157 | Pluth et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael D. Pluth (Eugene, Oregon); Matthew M. Cerda (Eugene, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262281 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 325/00 (20130101) Original (OR) Class C07C 327/22 (20130101) C07C 327/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078214 | Gangjee |
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| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | The present invention provides a compound of Formula XXVII: wherein X is CH2 or O, and R1 is H or CH3; or a salt or a hydrate of the compound, and further provides a pharmaceutical composition comprising the compound of Formula XXVII and one or more acceptable pharmaceutical carriers. A method of treating a patient having cancer comprising administering a therapeutically effective amount of a compound of Formula XXVII, or a pharmaceutical composition comprising a compound of Formula XXVII and one or more acceptable pharmaceutical carriers to the patient is disclosed. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571842 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078235 | Hazlehurst et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center And Research Institute, Inc. (Tampa, Florida); University of South Florida (Tampa, Florida); The Scripps Research Institute (La Jolla, California); Modulation Therapeutics (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center And Research Institute, Inc. (Tampa, Florida); The Scripps Research Institute (La Jolla, California); University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Lori Hazlehurst (Morgantown, West Virginia); Christoph Rader (Jupiter, Florida); Xiuling Li (Jupiter, Florida); Mark McLaughlin (Tampa, Florida) |
| ABSTRACT | The present invention concerns cyclic compounds, compositions comprising the cyclic compounds, linkers, a method of preparing a carrying agent:cyclic compound adduct, a method for treating disorders such as proliferation disorders (e.g., malignancies), bone deficiency diseases, and autoimmune diseases, and a method for suppressing the growth of, or inducing apoptosis in, cells (e.g., malignant cells). |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025382 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 1/00 (20130101) C07K 7/06 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/705 (20130101) C07K 14/70596 (20130101) C07K 2319/21 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078238 | Agbandje-McKenna et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Mavis Agbandje-McKenna (Gainesville, Florida); Mario Mietzsch (Gainesville, Florida) |
| ABSTRACT | This disclosure relates to variant AAVrh.10 particles engineered to escape host neutralizing antibodies but retain or improve transduction efficiency, and their use as gene delivery vehicles. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 16/338397 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2015/8518 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078239 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Institute for Research in Biomedicine (Bellinzona, Switzerland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Institute for Research in Biomedicine (Bellinzona, Switzerland) |
| INVENTOR(S) | Baoshan Zhang (Bethesda, Maryland); Guillaume Stewart-Jones (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland); John Mascola (Rockville, Maryland); Kai Xu (Bethesda, Maryland); Yongping Yang (Potomac, Maryland); Paul Thomas (Washington, District of Columbia); Gwo-Yu Chuang (Rockville, Maryland); Li Ou (Bethesda, Maryland); Peter Kwong (Washington, District of Columbia); Yaroslav Tsybovsky (Jefferson, Maryland); Wing-Pui Kong (Germantown, Maryland); Aliaksandr Druz (Germantown, Maryland); Davide Corti (Bellinzona, Switzerland); Antonio Lanzavecchia (Bellinzona, Switzerland) |
| ABSTRACT | Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject. |
| FILED | Wednesday, October 25, 2017 |
| APPL NO | 16/344772 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/155 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18634 (20130101) C12N 2760/18734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078246 | Walensky et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Newton, Massachusetts); Gregory H. Bird (Pelham, New Hampshire) |
| ABSTRACT | This disclosure features stapled peptide inhibitors (e.g., cysteine-reactive stapled peptides) of the anti-apoptotic protein, BFL-1, and methods of using same in the treatment of BFL-1 expressing cancers. |
| FILED | Friday, August 26, 2016 |
| APPL NO | 15/752358 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1761 (20130101) A61K 45/06 (20130101) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4747 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078259 | Tseng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Yu-Hua Tseng (Newton, Massachusetts); Matthew Lynes (Brookline, Massachusetts); Ruidan Xue (Shanghai, China PRC) |
| ABSTRACT | The invention provides methods and compositions relating to molecular targets identified as being capable of increasing or decreasing thermogenic potential in cells, including preadipocytes. Included in the invention are methods and compositions relating to inhibiting or suppressing the activity of an uncoupling protein 1 (UCP1) negative regulator, such as cardiac actin 1 (ACTC1), somatostatin receptor 1 (SSTR1), FAT atypical cadherin 1 (FAT1), and protein tyrosine phosphatase receptor type B (PTPRB). Also included in the invention are methods and compositions relating to activating a UCP1 positive regulator, such as phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 (PREX1), cortactin binding protein 2 (CTTNBP2), doublesex and mab-3-related transcription factor-like family A1 (DMRTA1), and endothelin receptor type B (ENDRB). The invention also provides methods and compositions relating to enrichment of cells having thermogenic potential based on cell surface markers, e.g., CD29, identified as being predictive of such. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/579885 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 35/35 (20130101) A61K 35/545 (20130101) A61K 38/177 (20130101) A61K 38/465 (20130101) A61K 38/1719 (20130101) A61K 38/1761 (20130101) A61K 38/1796 (20130101) Peptides C07K 14/705 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/75 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) Enzymes C12Y 301/03048 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078260 | Ferrone et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Soldano Ferrone (Boston, Massachusetts); Xinhui Wang (Boston, Massachusetts); Thomas P. Conrads (Reston, Virginia); Elvira Favoino (Bari, Italy); Brian L. Hood (Reston, Virginia) |
| ABSTRACT | Isolated monoclonal antibodies are disclosed herein that specifically bind endoplasmin. In some embodiments these antibodies are fully human. Recombinant nucleic acids encoding these antibodies, expression vectors including these nucleic acids, and host cells transformed with these expression vectors are also disclosed herein. In several embodiments the disclosed antibodies are of use for detecting and/or treating tumors that express endoplasmin, such as melanoma, breast cancer, head and neck squamous cell carcinoma, renal cancer, lung cancer, glioma, bladder cancer, ovarian cancer or pancreatic cancer. In one example, the tumor is a melanoma. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870532 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 47/6843 (20170801) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/303 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3038 (20130101) C07K 16/3053 (20130101) C07K 16/3069 (20130101) C07K 16/3092 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) C07K 2319/55 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 15/09 (20130101) C12N 15/62 (20130101) C12N 15/86 (20130101) C12N 15/8258 (20130101) C12N 2800/00 (20130101) C12N 2810/859 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/577 (20130101) G01N 2333/47 (20130101) G01N 2333/4727 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078276 | Larrick et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nepenthe Bioscience LLC (Sunnvale, California) |
| ASSIGNEE(S) | Nepenthe Bioscience LLC (Sunnyvale, California) |
| INVENTOR(S) | James Larrick (Sunnyvale, California); Bo Yu (Sunnyvale, California); Andrew Mendelsohn (Palo Alto, California); John C. Cambier (Denver, Colorado) |
| ABSTRACT | The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/591617 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078285 | Scholler et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Nathalie Scholler (San Jose, California); Aizhi Zhao (Drexel Hill, Pennsylvania); Donald Siegel (Lansdale, Pennsylvania); George Coukos (Vaud, Switzerland) |
| ABSTRACT | The invention relates to Anti-TEM 1 antibodies or antigen-binding fragments thereof, yeast libraries comprising the same, and prophylactic, diagnostic, and therapeutic methods using the same. |
| FILED | Monday, December 24, 2018 |
| APPL NO | 16/231876 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/2851 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078286 | Khan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Javed Khan (Derwood, Maryland); Sivasubramanian Baskar (Ellicott City, Maryland); Rimas J. Orentas (Seattle, Washington); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland); Tai Chi Cheuk (Germantown, Maryland) |
| ABSTRACT | Monoclonal antibodies selected from immunized mice, immunized rabbits and a human scFv library that specifically bind fibroblast growth factor receptor 4 (FGFR4) are described. Chimeric antigen receptors, antibody-drug conjugates, immunoconjugates, bispecific antibodies and immunoliposomes comprising the disclosed FGFR4-specific antibodies are also described. The antibody compositions can be used to diagnose or treat a FGFR4-positive cancer, such as rhabdomyosarcoma, lung cancer, liver cancer, breast cancer, pancreatic cancer or prostate cancer. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/761398 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/6803 (20170801) A61K 47/6849 (20170801) A61K 47/6911 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078300 | Bradley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Philip Bradley (Seattle, Washington); Barry L. Stoddard (Seattle, Washington) |
| ABSTRACT | Circular handed alpha-helical repeat proteins are described. The repeat proteins have a number of uses as scaffolds for geometrically precise, arrayed presentation of cell-signaling or immune-related protein and peptide epitopes, as well as numerous other therapeutic, diagnostic, and nanotechnological uses. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/802377 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 14/00 (20130101) C07K 14/001 (20130101) C07K 14/44 (20130101) C07K 14/47 (20130101) C07K 14/55 (20130101) C07K 19/00 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078471 | Batlle et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Daniel Batlle (Chicago, Illinois); Jan Wysocki (Chicago, Illinois) |
| ABSTRACT | Disclosed are variants of ACE2, pharmaceutical compositions comprising the variants of ACE2, and treatment methods for reducing Angiotensin II (1-8) plasma levels and/or increasing Angiotensin (1-7) plasma levels in a subject in need thereof. The disclosed variants of ACE2 may include polypeptide fragments of ACE2 having ACE2 activity for converting AngII (1-8) to Ang(1-7). Suitable subjects suitable for the disclosed methods of treatment may include subjects having or at risk for developing diabetic and non-diabetic chronic kidney disease, acute renal failure and its prevention, chronic kidney disease, severe hypertension, scleroderma and its skin, pulmonary, kidney and hypertensive complications, malignant hypertension, renovascular hypertension secondary to renal artery stenosis, idiopathic pulmonary fibrosis, liver fibrosis such as in liver cirrhosis patients, an aortic aneurysm, cardiac fibrosis and remodeling, left ventricular hypertrophy, and an acute stroke. |
| FILED | Monday, October 14, 2019 |
| APPL NO | 16/601545 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4813 (20130101) A61K 47/60 (20170801) A61K 47/68 (20170801) A61K 47/6929 (20170801) Peptides C07K 14/315 (20130101) C07K 14/765 (20130101) C07K 2319/21 (20130101) C07K 2319/30 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078480 | Guttman et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Mitchell Guttman (Los Angeles, California); Sofia A. Quinodoz (Pasadena, California); Mario R. Blanco (Los Angeles, California); Devdoot Majumdar (Colchester, Vermont) |
| ABSTRACT | Methods of detecting an interaction between a macromolecule and an interaction partner are described. Kits are also described. |
| FILED | Wednesday, September 18, 2019 |
| APPL NO | 16/575124 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1055 (20130101) Original (OR) Class C12N 15/1065 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/6845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078494 | Keller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Gordon Keller (Toronto, Canada); Stefan Irion (Toronto, Canada); Herve Luche (Ulm, Germany); Paul Gadue (New York, New York); Hans J. Fehling (Ulm, Germany) |
| ABSTRACT | The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus. |
| FILED | Friday, October 25, 2019 |
| APPL NO | 16/664291 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/15 (20130101) A01K 2217/00 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2510/00 (20130101) C12N 2800/30 (20130101) C12N 2830/85 (20130101) C12N 2840/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078495 | Kafri |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Tal Kafri (Carrboro, North Carolina) |
| ABSTRACT | The present invention provides an integration-defective lentiviral vector based on a parental lentivirus and related methods, the integration-defective lentiviral vector including one or more of the following: (a) a mutation, deletion or other modification of one or more binding sites for a host factor involved in gene silencing; (b) an addition of one or more binding sites for a transcription activator, which can be natural (such as but not limited to ubiquitous and/or tissue/cell type specific) including but not limited to SP1 NFkB, or synthetic including but not limited to binding sites for tetracycline regulated trans activators tTA, rtTA, tT65, and/or rtT65; (c) one or more nucleic acid sequences from a SV40 genome, wherein the one or more sequences are obtained from a region of the SV40 genome upstream to the SV40 poly-adenylation signal; (d) a shRNA expression cassette, which encodes a shRNA directed to a host gene involved in epigenetic silencing and/or in DNA repair pathways; or (e) any combination of (a), (b), (c) and (d), wherein as compared to the parental lentivirus, the integration-defective lentiviral vector resists gene silencing. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/768438 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/531 (20130101) C12N 2330/51 (20130101) C12N 2710/22022 (20130101) C12N 2740/16043 (20130101) C12N 2830/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078496 | Brosh, Sr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Ran Brosh, Sr. (New York, New York); Ihor R. Lemischka (New York, New York); Ning Zheng (Shoreline, Washington) |
| ABSTRACT | The present invention relates to a system for F-box hormone receptor regulated protein expression in mammalian cells. The system includes a silencing nucleic acid molecule comprising a first promoter and an shRNA operably linked to the first promoter, where the shRNA silences expression of a target protein. The system also includes an expression nucleic acid molecule comprising a second promoter, an F-box hormone receptor operably linked to the second promoter, and a nucleic acid molecule encoding a fusion protein comprising a degron fused to the target protein, where the nucleic acid molecule encoding the fusion protein is operably linked to the second promoter. Also disclosed are vectors comprising the system of the present application and methods of use thereof. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 16/093436 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) A61K 48/0083 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2799/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078520 | Church et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Evan R. Daugharthy (Cambridge, Massachusetts) |
| ABSTRACT | Methods of making a three-dimensional matrix of nucleic acids within a cell is provided. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/157243 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 2565/501 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078533 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaoliang Sunney Xie (Lexington, Massachusetts); Katsuyuki Shiroguchi (Arlington, Massachusetts); Peter A. Sims (Cambridge, Massachusetts); Tony Z. Jia (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872571 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/131 (20130101) C12Q 2525/301 (20130101) C12Q 2537/16 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078535 | Sharma et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
| ASSIGNEE(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
| INVENTOR(S) | Salil Sharma (Bloomington, Indiana); Hui-Chen Lu (Bloomington, Indiana) |
| ABSTRACT | Compositions and methods are provided for the early detection of neuroinflammation in a patient in a presymptomatic stage of a neurodegenerative disease. The method comprises identifying patients with elevated expression levels of a micro RNA selected from the group consisting of miR142-3p, miR142-5p, miR181a, miR181b, miR219-3p and miR219-5p. The identified patients can then be treated with a therapeutic pharmaceutical composition comprising antimiR oligonucleotides. |
| FILED | Saturday, July 07, 2018 |
| APPL NO | 16/631866 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078540 | Garraway et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Levi A. Garraway (Newton, Massachusetts); Cory M. Johannessen (Roslindale, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); BROAD INSTITUTE, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Levi A. Garraway (Newton, Massachusetts); Cory M. Johannessen (Roslindale, Massachusetts) |
| ABSTRACT | A method of identifying a subject having cancer who is likely to benefit from treatment with a combination therapy with a RAF inhibitor and a second inhibitor is provided. A method of treating cancer in a subject in need thereof is also provided and includes administering to the subject an effective amount of a RAF inhibitor and an effective amount of a second inhibitor, wherein the second inhibitor is a MEK inhibitor, a CRAF inhibitor, a CrkL inhibitor or a TPL2/COT inhibitor. A method of identifying a kinase target that confers resistance to a first inhibitor is also provided. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/480126 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 9/1205 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/11024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079214 | Zhou |
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| FUNDED BY |
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| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | LEHIGH UNIVERSITY (, None) |
| INVENTOR(S) | Chao Zhou (Bethlehem, Pennsylvania) |
| ABSTRACT | Integrated photonic chips and related systems and methods suitable for space-division multiplexing optical coherence tomography scanning are disclosed. In one embodiment, the photonic chip comprises a substrate, an optical input port which receives an incident sampling beam from an external light source, a plurality of optical output ports configured to transmit a plurality of sampling beams from the chip to a sample to capture scanned images of the sample, and a plurality of interconnected and branched waveguide channels formed in the substrate. Waveguide channels in a splitter region divide the sampling beam into the plurality of sampling beams at the output ports. Terminal portions of the waveguide channels in a time delay region associated with each output port have different predetermined lengths to create an optical time delay between the sampling beams. In some embodiments, the chip further comprises an interferometer region to create interference patterns. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 16/612905 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 2562/0233 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) G01B 9/02019 (20130101) G01B 9/02028 (20130101) G01B 9/02051 (20130101) Original (OR) Class G01B 9/02091 (20130101) G01B 2290/65 (20130101) Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/2861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079380 | Marr |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Kieren Marr (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galF)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galF antigens and improvement of sensitivity of galF antigen detection assays. The methods include minimizing intelectin-1 binding to galF antigens and improvement of monoclonal antibody binding. The detection methods are useful for identifying the presence of microbial antigens related to bacterial, fungal, and parasitic pathogens, including Streptococcus pneumoniae, Aspergillus species, Fusarium species, Coccidioides species, Cryptococcus species, Histoplasma species, and Leishmania species. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 16/750720 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/14 (20130101) C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/569 (20130101) G01N 33/54366 (20130101) G01N 33/56911 (20130101) G01N 33/56961 (20130101) Original (OR) Class G01N 2400/02 (20130101) G01N 2469/10 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079383 | Haber et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Daniel A. Haber (Newton, Massachusetts); Shyamala Maheswaran (Lexington, Massachusetts); David T. Miyamoto (Wellesley, Massachusetts) |
| ABSTRACT | Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or for the purpose of monitoring treatment efficacy for prostate cancers that are likely hormone resistant. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682224 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/167 (20130101) A61K 31/496 (20130101) A61K 2039/505 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079384 | Mulvihill et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Sean J. Mulvihill (Salt Lake City, Utah); Matthew A. Firpo (Salt Lake City, Utah) |
| ABSTRACT | The present invention provides biomarker compositions and methods for the diagnosis and prognosis of PDAC. In a particular embodiment, the invention provides methods and compositions for screening, diagnosis and prognosis of early stage, asymptomatic PDAC. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 16/658937 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) Original (OR) Class G01N 33/57488 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079394 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Thomas J. Wang (Nashville, Tennessee); Deepak K. Gupta (Nashville, Tennessee); Quinn S. Wells (Nashville, Tennessee); Robert E. Gerszten (Boston, Massachusetts) |
| ABSTRACT | Methods for detecting angiopoietin-2 (Angpt-2) and/or thrombospondin-2 (Tsp-2) in a sample involve obtaining or having obtained a blood or plasma sample from a subject; and detecting Angpt-2 and Tsp-2 in the sample. Detecting can involve performing an assay to determine whether the sample includes Angpt-2 and/or Tsp-2 or elevated levels of Angpt-2 and/or Tsp-2. Elevated levels are indicative of acute heart failure. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045465 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/515 (20130101) G01N 2333/4704 (20130101) G01N 2800/52 (20130101) G01N 2800/325 (20130101) G01N 2800/7014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079395 | Beshiri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Abbott Laboratories (Abbott Park, Illinois); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Abbott Laboratories (Abbott Park, Illinois); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Agim Beshiri (Abbott Park, Illinois); Arshed A. Quyyumi (Atlanta, Georgia) |
| ABSTRACT | Provided herein are methods for predicting or determining whether a subject with coronary artery disease is likely to experience or develop a major adverse cardiovascular event (MACE) based on determining cardiac troponin (cTnI) levels in a human at rest and during or after exercise. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/805136 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/32 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079448 | Griswold et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Mark A. Griswold (Shaker Heights, Ohio); Anagha Deshmane (Cleveland Heights, Ohio) |
| ABSTRACT | A system and method is provided for correcting receiver bias during quantitative proton density mapping with magnetic resonance fingerprinting (MRF). The method comprises acquiring MRF data from a region of interest in a subject by performing a pulse sequence using a series of varied sequence blocks to elicit a series of signal evolutions. The method further comprises comparing the MRF data to a MRF dictionary to simultaneously map proton density and another tissue property from the region of interest, the proton density map having a proton density signal and a receiver sensitivity profile signal. The method also includes quantifying the proton density signal and the receiver sensitivity profile signal using parameters provided by the proton density map and the tissue property map, and generating a quantitative map from the region of interest based on the proton density signal. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 16/461549 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/246 (20130101) Original (OR) Class G01R 33/565 (20130101) G01R 33/4828 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079453 | Liang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Zhi-Pei Liang (Champaign, Illinois); Fan Lam (Urbana, Illinois) |
| ABSTRACT | A new method is developed for ultrafast, high-resolution magnetic resonance spectroscopic imaging (MRSI) using learned spectral features. The method uses Free Induction Decay (FID) based ultrashort-TE and short-TR acquisition without any solvent suppression pulses to generate the desired spatiospectral encodings. The spectral features for the desired molecules are learned from specifically designed “training” data by taking into account the resonance structure of each compound generated by quantum mechanical simulations. A union-of-subspaces model that incorporates the learned spectral features is used to effectively separate the unsuppressed water/lipid signals, the metabolite signals, and the macromolecule signals. The unsuppressed water spectroscopic signals in the data can be used for various purposes, e.g., removing the need of additional auxiliary scans for calibration, and for generating high quality quantitative tissue susceptiability mapping etc. Simultaneous spatiospectral reconstructions of water, lipids, metabolite and macromolecule can be obtained using a single 1H-MRSI scan. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/643239 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/246 (20130101) G01R 33/465 (20130101) G01R 33/485 (20130101) Original (OR) Class G01R 33/4625 (20130101) G01R 33/4816 (20130101) G01R 33/4826 (20130101) G01R 33/4828 (20130101) G01R 33/5608 (20130101) G01R 33/5615 (20130101) G01R 33/34092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082386 | Chu et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Chung K. Chu (Statham, Georgia); Jianing Wang (San Diego, California) |
| ABSTRACT | The present invention relates to 2′-Fluoro-6′-methylene carbocyclic nucleosides, pharmaceutical compositions containing these nucleosides and their use in the treatment or prophylaxis of a number of viral infections and secondary disease states and conditions thereof, especially including Hepatitis B virus (HBV) and secondary disease states and conditions thereof (cirrhosis and liver cancer), Heptatitis C virus (HCV), Herpes Simplex virus I and II (HSV-1 and HSV-2), cytomegalovirus (CMV), Varicella-Zoster Virus (VZV) and Epstein Barr virus (EBV) and secondary cancers which occur thereof (lymphoma, nasopharyngeal cancer, including drug resistant (especially including lamivudine and/or adefovir resistant) and other mutant forms of these viruses, especially HBV. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696708 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/522 (20130101) A61K 31/675 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Heterocyclic Compounds C07D 473/18 (20130101) C07D 473/34 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/10 (20130101) H04L 51/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11077057 | Chipre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Anthony J. Chipre (Rochester, New York); SonBinh T. Nguyen (Evanston, Illinois) |
| ABSTRACT | Provided herein are small unilamellar vesicles with surface-displayed polymer moieties, and methods of use and manufacture thereof. In particular, provided herein are polymer-grafted nanobins, and methods of drug delivery therewith. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738473 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Y10S 977/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077183 | Tang et al. |
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| FUNDED BY |
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| APPLICANT(S) | MicroVAX, LLC (Warrenton, Virginia) |
| ASSIGNEE(S) | MicroVAX, LLC (Warrenton, Virginia) |
| INVENTOR(S) | Yucheng Tang (San Diego, California); Albert B. Deisseroth (Potomac, Maryland) |
| ABSTRACT | Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described. |
| FILED | Thursday, December 29, 2016 |
| APPL NO | 15/393543 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/53 (20130101) A61K 2039/55 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70575 (20130101) C07K 2319/02 (20130101) C07K 2319/06 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/20034 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077200 | Guerry et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Arlinton, Virginia) |
| INVENTOR(S) | Patricia Guerry (Silver Spring, Maryland); Mario Artur Monteiro (Guelph, Canada); Stephen Savarino (Kensington, Maryland) |
| ABSTRACT | The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaccharide from Shigella spp. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/132948 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/105 (20130101) A61K 39/0258 (20130101) A61K 39/0283 (20130101) A61K 47/646 (20170801) Original (OR) Class A61K 47/6415 (20170801) A61K 2039/70 (20130101) A61K 2039/6037 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/245 (20130101) C07K 16/44 (20130101) C07K 16/1232 (20130101) C07K 16/1267 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2319/35 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077213 | Bawendi et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi G. Bawendi (Cambridge, Massachusetts); Daniel K. Harris (Wilton, Connecticut); Oliver T. Bruns (Boston, Massachusetts); Thomas S. Bischof (Medford, Massachusetts) |
| ABSTRACT | InAs based core-shell particles which leads to tunable, narrow emitting semiconductor nanocrystals with a very high quantum yield which can be preserved in physiological buffers with long stability can used for short wavelength infrared (SWIR) imaging. Increased resolution with reduced read time and increased imaging frequency can provide advantages in in vivo applications. |
| FILED | Tuesday, April 22, 2014 |
| APPL NO | 14/258681 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/489 (20130101) A61B 5/02007 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0067 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/565 (20130101) C09K 11/883 (20130101) C09K 11/7492 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/40 (20130101) C30B 29/60 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/83 (20130101) Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11077494 — Method and casting core for forming a landing for welding a baffle inserted in an airfoil
| US 11077494 | Propheter-Hinckley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut) |
| ABSTRACT | A method and casting core for forming a landing for welding a baffle inserted into an airfoil are disclosed, wherein the baffle landing of the blade or vane is formed in investment casting by the casting core rather than by wax, reducing tolerances and variability in the location of the baffle inserted into the cooling cavity of airfoil when the baffle is welded to the baffle landing. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/223861 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Foundry Moulding B22C 1/00 (20130101) B22C 9/04 (20130101) B22C 9/10 (20130101) B22C 9/18 (20130101) B22C 9/24 (20130101) B22C 9/103 (20130101) B22C 9/108 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 25/02 (20130101) Original (OR) Class B22D 29/001 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/188 (20130101) F01D 9/041 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/211 (20130101) F05D 2230/232 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) F05D 2240/126 (20130101) F05D 2260/201 (20130101) F05D 2300/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077517 | Smitherman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Concurrent Technologies Corporation (Johnstown, Pennsylvania) |
| ASSIGNEE(S) | Concurrent Technologies Corporation (Johnstown, Pennsylvania) |
| INVENTOR(S) | Mark. T. Smitherman (Johnstown, Pennsylvania); Timothy G. Freidhoff (Johnstown, Pennsylvania); Paul I. Sleppy (Penn Run, Pennsylvania); Daniel B. George, II (Homer City, Pennsylvania); James C. McHenry (Latrobe, Pennsylvania); Alan W. Baum (Orlando, Florida) |
| ABSTRACT | Embodiments can include a self-reacting friction stir weld (“FSW”) tool. The device can be configured to be portable and produce full penetration welds in situ. The FSW tool can include a system that cuts out a portion of the structure surrounding a defective portion of the structure. A work-piece can be inserted within the removed portion and friction stir welded to the structure via the FSW tool. A superior repair as compared to merely welding the defect can be achieved by replacing a portion of the structure surrounding the defect as opposed to merely welding the defect (e.g., the crack). A controlled geometric shaped weld beam can be generated for the interface between the work-piece and the structure, which may led to a stronger, more reliable weld. |
| FILED | Wednesday, December 06, 2017 |
| APPL NO | 15/832943 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/123 (20130101) B23K 20/125 (20130101) Original (OR) Class B23K 20/127 (20130101) B23K 20/1255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077587 | Pikul et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | James Pikul (Ithaca, New York); Itai Cohen (Ithaca, New York); Robert Shepherd (Ithaca, New York) |
| ABSTRACT | The present disclosure may be embodied as a method for creating a restriction pattern from a mask material having a strain (εmask) an for mapping elastomeric membrane having a strain (εmembrane) into a target 3D shape. The method may include discretizing the target 3D shape into a plurality of radial segments, and a radial strain (εr) is determined for each radial position (r) on each radial segment of the plurality of radial segments. A restriction pattern is determined, wherein the restriction pattern comprises a quantity of mask material for each position r to provide a composite strain (εmask, εsilicone). In some embodiments, the method further includes depositing a first membrane layer into a mold and placing mask material into the first membrane layer according to the determined restriction pattern. The first membrane layer is cured. |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/161029 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0805 (20130101) B29C 39/006 (20130101) B29C 39/10 (20130101) B29C 41/003 (20130101) B29C 41/12 (20130101) B29C 41/20 (20130101) B29C 41/22 (20130101) B29C 41/52 (20130101) Original (OR) Class B29C 2035/0838 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) B29K 2105/206 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/702 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077590 | Bartlett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Bartlett (Mitchell, Indiana); Elizabeth O'Neill (Washington, Indiana); Robert Moser (Heltonville, Indiana); Roger Dickerhoof (Bloomington, Indiana); Carl Miller (Bedford, Indiana); Joshua Jeffers (Loogootee, Indiana); Bryan Woosley (Bedford, Indiana); James Merryfield (Bedford, Indiana) |
| ABSTRACT | A mold assembly includes a first upper portion, a second upper portion, and a base removably coupled to each other. A method of manufacturing an electrical connector with the mold assembly includes preheating a resin, mixing the resin with a hardener, preheating the mold assembly, injecting the resin hardener mixture into the mold assembly, and curing the resin hardener mixture. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/364542 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 45/26 (20130101) B29C 45/64 (20130101) B29C 45/14549 (20130101) B29C 45/14639 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/36 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 2003/265 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 63/00 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 43/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077632 | Folgar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3D Systems, Inc. (Rock Hill, South Carolina) |
| ASSIGNEE(S) | 3D SYSTEMS, INC. (Rock Hill, South Carolina) |
| INVENTOR(S) | Luis N Folgar (Lake Oswego, Oregon); Carlos E Folgar (Painted Post, New York); Francisco Folgar (Midlothian, Virginia); Christian E Folgar (Langhorne, Pennsylvania); Jim Williams (Erwinna, Pennsylvania) |
| ABSTRACT | In one aspect, methods of post-processing an object made by additive manufacturing are described herein. In some embodiments, a method of post-processing an object described herein comprises providing the object in a microwave absorptive state and exposing the object in the absorptive state to a field of microwave radiation. In some cases, providing an object in a microwave absorptive state comprises heating the object, including by non-microwave heating. Moreover, in some embodiments, the object is exposed to a uniform or substantially uniform field of microwave radiation in a microwave cavity. In addition, in some instances, exposing an object to a field of microwave radiation in a manner described herein comprises increasing the density of the object and/or reducing the volume of the object, including in an isotropic or substantially isotropic manner. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212399 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) B29C 64/364 (20170801) B29C 71/04 (20130101) Original (OR) Class B29C 2035/0855 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078125 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL LABORATORIES, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Chaoyin Zhou (Chino, California); Zak C. Eckel (Mewbury Park, California); Alan J. Jacobsen (Woodland Hills, California); William Carter (Calabasas, California) |
| ABSTRACT | A cellular material includes a continuous solid phase including an ordered ceramic material, the solid phase having a solid core including the ordered ceramic material. A composition for forming a cellular material includes: a first UV curable pre-ceramic monomer; a second UV curable pre-ceramic monomer; and a photoinitiator. A method of forming at least one ceramic waveguide includes: securing a volume of a composition including a UV curable pre-ceramic monomer; exposing the composition to a light source to form at least one polymer waveguide including a pre-ceramic material; and converting the pre-ceramic material of the polymer waveguide to a ceramic material to form a ceramic waveguide. |
| FILED | Thursday, March 03, 2016 |
| APPL NO | 15/060488 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/00 (20130101) C04B 38/0006 (20130101) Original (OR) Class C04B 38/062 (20130101) C04B 2235/483 (20130101) C04B 2235/3895 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078139 | Harvey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California) |
| ABSTRACT | A method for making cyclopentadiene fuels comprising producing cyclopent-2-en-1-one or a mixture of cyclopent-2-en-1-one from a bio-based source. The cyclopent-2-en-1-one or the mixture of cyclopent-2-en-1-one is hydrogenated, thereby forming cyclopent-2-en-1-ol or a mixture of cyclopent-2-en-1-ol. The cyclopent-2-en-1-ol or the mixture of cyclopent-2-en-1-ol is dehydrated with a dehydrating agent, thereby forming cyclopentadiene or a mixture of cyclopentadiene. The cyclopentadiene or mixture of cyclopentadiene is converted to dicyclopentadiene or dihydrodicyclopentadiene. The dicyclopentadiene or dihydrodicyclopentadiene is hydrogenated, thereby forming tetrahydrodicyclopentadiene. The tetrahydrodicyclopentadiene is isomerized, thereby forming exo-tetrahydrodicyclopentadiene. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/559778 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) C07C 2/52 (20130101) C07C 5/2206 (20130101) C07C 7/04 (20130101) C07C 29/145 (20130101) Original (OR) Class C07C 45/41 (20130101) C07C 45/59 (20130101) C07C 45/61 (20130101) C07C 45/66 (20130101) C07C 51/36 (20130101) C07C 51/42 (20130101) C07C 67/08 (20130101) C07C 2521/02 (20130101) C07C 2527/18 (20130101) C07C 2531/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078334 | Rueschhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of Americas as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Lisa M. Rueschhoff (Dayton, Ohio); Matthew B. Dickerson (Beavercreek, Ohio) |
| ABSTRACT | The present invention relates to gels and processes for making ceramic nanostructures, ceramic nanostructures made by such processes, and methods of using such ceramic nanostructures. Such process is templated via block copolymer self-assembly but does not require any post processing thermal and/or solvent annealing steps. As a result, such process is significantly more efficient and scalable than other processes that are templated via block copolymer self-assembly and yields a ceramic having a pore structure/shape that provides the ceramic with a higher ductility than traditional ceramics. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/572723 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/06 (20130101) C08G 77/12 (20130101) Original (OR) Class C08G 77/20 (20130101) C08G 77/44 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078467 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Yousong Ding (Gainesville, Florida); Ran Zuo (Gainesville, Florida) |
| ABSTRACT | The disclosure relates to the field of fusion proteins. In some aspects, the disclosure relates to artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes and uses thereof. In some aspects, the disclosure relates to corn-pounds produced by artificial cytochrome P450 enzymes. |
| FILED | Thursday, October 26, 2017 |
| APPL NO | 16/345224 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/80 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0042 (20130101) C12N 9/0071 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/10 (20130101) C12P 17/16 (20130101) C12P 17/165 (20130101) C12P 17/182 (20130101) Enzymes C12Y 106/02004 (20130101) C12Y 114/14001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078469 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Basil Hubbard (Edmonton, Canada); Ahmed Hussein Badran (Somerville, Massachusetts) |
| ABSTRACT | Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One current drawback of TALEs is that the 5′ nucleotide of the target is specific for thymine (T). TALE domains with alternative 5′ nucleotide specificities could expand the scope of DNA target sequences that can be bound by TALEs. Another drawback of TALEs is their tendency to bind and cleave off-target sequence, which hampers their clinical application and renders applications requiring high-fidelity binding unfeasible. This disclosure provides methods and strategies for the continuous evolution of proteins comprising DNA-binding domains, e.g., TALE domains. In some aspects, this disclosure provides methods and strategies for evolving such proteins under positive selection for a desired DNA-binding activity and/or under negative selection against one or more undesired (e.g., off-target) DNA-binding activities. Some aspects of this disclosure provide engineered TALE domains and TALEs comprising such engineered domains, e.g., TALE nucleases (TALENs), TALE transcriptional activators, TALE transcriptional repressors, and TALE epigenetic modification enzymes, with altered 5′ nucleotide specificities of target sequences. Engineered TALEs that target ATM with greater specificity are also provided. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804228 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/62 (20130101) C12N 15/90 (20130101) C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078698 | Lang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Robert J. Lang (Alamo, California); Larry L. Howell (Orem, Utah); Spencer P. Magleby (Provo, Utah); Todd G. Nelson (Provo, Utah) |
| ABSTRACT | A hinged mechanism includes: panels; and hinges connecting respective pairs of the panels to each other in a closed loop so that the hinged mechanism is non-planar, wherein at least one of the hinges is a rolling-contact hinge. All of the hinges can be rolling-contact hinges. The closed-loop hinged mechanism can comprise at least four hinges, each of the at least four hinges being a sole connection between a respective adjacent pair of the panels. A cross section of rolling surfaces of the rolling-contact hinge can be circular. A cross section of rolling surfaces of the rolling-contact hinge can be non-circular. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/422195 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hinges or Suspension Devices for Doors, Windows or Wings E05D 1/00 (20130101) E05D 1/02 (20130101) E05D 1/04 (20130101) E05D 3/04 (20130101) E05D 3/06 (20130101) E05D 3/10 (20130101) Original (OR) Class E05D 3/122 (20130101) E05D 2003/025 (20130101) Technical Subjects Covered by Former US Classification Y10T 16/5474 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078805 | Joly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Michael M. Joly (Hebron, Connecticut); Simon W. Evans (Farmington, Connecticut); Dilip Prasad (North Granby, Connecticut); Gorazd Medic (West Hartford, Connecticut); Georgi Kalitzin (West Hartford, Connecticut); Dmytro Mykolayovych Voytovych (Rocky Hill, Connecticut) |
| ABSTRACT | A compressor for use in a gas turbine engine including: an airfoil configured to rotate about an engine central longitudinal axis of the gas turbine engine; a casing, the casing including a radially inward surface; and a groove located within the casing opposite the airfoil, the groove is recessed in a radially outward direction from the radially inward surface of the casing, wherein the groove is defined by a forward groove wall, an aft groove wall opposite the forward groove wall, and a base groove interposed between the forward groove wall and the aft groove wall, and wherein the forward groove wall is operably shaped to generate an aft directed jet. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384076 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/10 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078897 | Reeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Jonathan Reeh (College Station, Texas); Jeffrey S. Parkey (College Station, Texas); Alan Cisar (Cypress, Texas); Duncan Hitchens (Allen, Texas) |
| ABSTRACT | The present invention includes an electrochemical actuator pump and method of making the same, comprising a membrane electrode assembly comprising an ion exchange membrane, a first and a second catalyzed porous electrode in contact with opposing sides of the ion exchange membrane; a first gas chamber in fluid communication with the first electrode, and a second gas chamber in fluid communication with the second electrode; and a controller for controllably reversing the polarity of a voltage source electrically coupled to the first and second electrodes, wherein the controller causes a first polarity at the first electrode to function as an anode and the second electrode to function as a cathode, wherein the first polarity simultaneously decreases the hydrogen gas pressure in the first hydrogen gas chamber and increases the hydrogen gas pressure in the second hydrogen gas chamber, with additional embodiment using MOF or Ni—H batteries. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015958 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 19/24 (20130101) F04B 43/06 (20130101) F04B 43/0054 (20130101) Original (OR) Class F04B 45/02 (20130101) F04B 45/024 (20130101) F04B 45/0336 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078950 | Wymore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Jacob L. Wymore (Huntsville, Alabama); Ross Warlick (Huntsville, Alabama); Eric Klasen (Tucson, Arizona) |
| ABSTRACT | A biasing system for use with a fastener is disclosed. The biasing system can include a sleeve configured to be disposed about a shank of a fastener and operable to form at least a portion of a first load path between the fastener and a component coupled to the fastener to preload the fastener through the sleeve. The biasing system can also include a spring configured to be associated with the sleeve and operable to form at least a portion of a second load path parallel to the first load path between the fastener and the component to facilitate biasing the fastener away from the component. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 15/905745 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/0266 (20130101) F16B 31/04 (20130101) F16B 39/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079227 | Fertig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Chad Fertig (Bloomington, Minnesota); Arthur Savchenko (Kirkland, Washington); Steven Tin (Plymouth, Minnesota); Neil Krueger (Saint Paul, Minnesota); Joshua Dorr (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure is related to devices, systems, and techniques for determining, using an electro-opto-mechanical accelerometer system, a frequency value in order to determine an acceleration value. For example, an accelerometer system includes a light-emitting device configured to emit an optical signal and a circuit. The circuit is configured to determine a frequency value corresponding to the optical signal and determine an acceleration value based on the frequency value. Additionally, the accelerometer system includes a housing that encloses the light-emitting device, the circuit, and Helium gas, where the Helium gas defines a partial pressure within a range between 0.1 torr and 760 torr. |
| FILED | Monday, April 01, 2019 |
| APPL NO | 16/371657 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5614 (20130101) Original (OR) Class G01C 19/5621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079293 | Stephens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America US Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES of AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Catherine S Stephens (Clinton, Mississippi); Clifford E Grey (Vicksburg, Mississippi); Roland Fuentes (Owens Cross Roads, Alabama); Larry Watkins (Meridianville, Alabama) |
| ABSTRACT | The method and system disclosed herein allow pressure profile data to be collected remotely from multiple autonomous sensors without entering the blast radius. The system obtains a GPS synchronized time value for detonation and obtains subsequent synchronized pressure data sets overtime from multiple independently functioning remote and correlates that data from each transducer with the initial detonation event. |
| FILED | Saturday, September 30, 2017 |
| APPL NO | 15/721870 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Blasting F42D 5/04 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079314 | Fontenot et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ross S. Fontenot (Montgomery Village, Maryland); Veerendra K. Mathur (Beltsville, Maryland); John H. Barkyoumb (Kensington, Maryland) |
| ABSTRACT | According to exemplary practice of the present invention, a probe laser beam is aligned with a position detector and is spatially/geometrically related to a pump laser beam. A temperature gradient is produced in a medium by the pump beam. Since an increase or decrease in the temperature of the medium is related to an increase or decrease in the refractive index of the medium, position sensing of the deflection of the probe beam relative to the pump beam indicates whether the medium is heating or cooling. |
| FILED | Tuesday, September 25, 2018 |
| APPL NO | 16/141910 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/171 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079383 | Haber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Daniel A. Haber (Newton, Massachusetts); Shyamala Maheswaran (Lexington, Massachusetts); David T. Miyamoto (Wellesley, Massachusetts) |
| ABSTRACT | Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or for the purpose of monitoring treatment efficacy for prostate cancers that are likely hormone resistant. |
| FILED | Monday, August 21, 2017 |
| APPL NO | 15/682224 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/167 (20130101) A61K 31/496 (20130101) A61K 2039/505 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079578 | Stonely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Aaron Stonely (McKinney, Texas); Stephen Felix Sagan (Lexington, Massachusetts); Brian M. Graue (McKinney, Texas) |
| ABSTRACT | A telescope includes a primary mirror, a secondary mirror configured to move along a first axis, and a tertiary mirror configured to move along a second axis. The secondary and tertiary mirrors are configured to move along respective axes in a synchronized manner to focus a beam of electromagnetic radiation from the primary mirror. The telescope further may include an anamorphic deformable mirror configured to achieve wavefront control and correction of optical aberrations. The telescope further may include a first linear actuator configured to move the secondary mirror along the first axis and a second linear actuator configured to move the tertiary mirror along the second axis. |
| FILED | Thursday, December 26, 2019 |
| APPL NO | 16/727091 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 17/082 (20130101) G02B 17/0631 (20130101) G02B 17/0642 (20130101) Original (OR) Class G02B 17/0647 (20130101) G02B 23/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079652 | Abouraddy et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Ayman F. Abouraddy (Orlando, Florida); Ali Kazemi Jahromi (Orlando, Florida); Massimo L. Villinger (Orlando, Florida); Ahmed El Halawany (Orlando, Florida); Soroush Shabahang (Orlando, Florida); Hasan Esat Kondakci (Orlando, Florida) |
| ABSTRACT | The present disclosure is directed to systems and methods for omniresonant broadband coherent perfect absorption of incoherent light over large bandwidths. The apparatus and methods that enable 100% effective optical absorption in a structure, irrespective of the material from which it is constructed, over a large, continuous bandwidth (omniresonance) in ultrathin devices. Specifically, we demonstrate achromatic optical absorption (omniresonance) in a planar Fabry-Pérot micro-cavity via angularly multiplexed phase-matching. By assigning each wavelength to an appropriate angle of incidence, the micro-cavity is rendered absorbing with continuous spectral range. For example, the linewidth of a single-order 0.7 nm wide resonance is de-slanted in spectral-angular space to become a 70 nm wide achromatic resonance spanning multiple cavity free spectral ranges. The embodied invention can have important applications in, e.g., harvesting solar energy, white-light micro-lasers, and other broadband resonantly enhanced optical effects. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/119348 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/21 (20130101) Original (OR) Class G02F 1/0126 (20130101) G02F 1/213 (20210101) G02F 2203/05 (20130101) G02F 2203/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079737 | Gruenwald et al. |
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| FUNDED BY |
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| APPLICANT(S) | Benjamin C. Gruenwald (Evansville, Indiana); Tansel Yucelen (Tampa, Florida); Kadriye Merve Dogan (Tampa, Florida); Jonathan A. Muse (Beavercreek, Ohio) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Benjamin C. Gruenwald (Evansville, Indiana); Tansel Yucelen (Tampa, Florida); Kadriye Merve Dogan (Tampa, Florida); Jonathan A. Muse (Beavercreek, Ohio) |
| ABSTRACT | The present disclosure describes an actuator system comprising an actuator unit that is configured to be positioned next to a structure; and an adaptive controller unit that is configured to receive a command input for the actuator unit and output an actuator command based on a reference model of a physical system that includes the actuator unit and the structure, wherein the actuator command does not alter trajectories of the reference model. In various embodiments, the uncertain dynamical system of the physical system is augmented with the actuator dynamics to provide improved stability. |
| FILED | Thursday, December 27, 2018 |
| APPL NO | 16/233666 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4083 (20130101) Original (OR) Class G05B 2219/49069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079747 | Matei et al. |
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| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | Ion Matei (Sunnyvale, California); Jeng Ping Lu (Fremont, California); Saigopal Nelaturi (Mountain View, California); Julie A. Bert (East Palo Alto, California); Lara S. Crawford (Belmont, California); Armin R. Volkel (Mountain View, California); Eugene M. Chow (Palo Alto, California) |
| ABSTRACT | The system and method described allow for real-time control over positioning of a micro-object. A movement of at least one micro-object suspended in a medium can be induced by a generation of one or more forces by electrodes proximate to the micro-object. Prior to inducing the movement, a simulation is used to develop a model describing a parameter of an interaction between each of the electrodes and the micro-object. A function describing the forces generated by an electrode and an extent of the movement induced due to the forces is generated using the model. The function is used to design closed loop policy control scheme for moving the micro-object towards a desired position. The position of the micro-object is tracked and taken into account when generating control signals in the scheme. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 16/734147 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 17/02 (20130101) G05B 19/41885 (20130101) Original (OR) Class G05B 2219/32359 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) G06T 7/155 (20170101) G06T 7/194 (20170101) G06T 2207/20021 (20130101) G06T 2207/30164 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079773 | Muhleman |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel H. Muhleman (San Diego, California) |
| ABSTRACT | A lighter-than-air (LTA) vehicle navigation system and vehicle. The navigation system includes a first wind probing device disposed at a first probe position, wherein the first wind probing device is in communication, via a first probe communications link, with a body communication system. The navigation system also includes a second wind probing device disposed at a second probe position, wherein the second wind probing device is in communication, via a second probe communications link, with the body communication system. The navigation system also includes a wind variation detection system configured to determine wind information, including at least a wind direction, for the first wind probing device and the second wind probing device. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661193 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/51 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080179 | Landsborough et al. |
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| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jason A. Landsborough (San Diego, California); Stephen T. Harding (San Diego, California); Bryan T. Beabout (San Diego, California); Emmanuel J. Orozco (San Diego, California) |
| ABSTRACT | An initial test variable determined by a fuzz tester to cause a faulty response of an original computer program due to a bug within the original computer program is added to a suite of test variables. Computer program candidates that are functionally equivalent to the original computer program are tested using a suite of test variables including the initial test variable. The computer program candidates are modified and selected using a genetic algorithm based on results of the testing to produce bug-free computer program candidates that are functionally equivalent to the original computer program. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/392951 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3684 (20130101) G06F 11/3688 (20130101) G06F 11/3692 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080236 | Yin et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Heng Yin (Riverside, California); Xunchao Hu (Riverside, California); Sheng Yu (Riverside, California); Yu Zheng (Riverside, California) |
| ABSTRACT | A novel high-throughput embedding generation and comparison system for executable code is presented in this invention. More specifically, the invention relates to a deep-neural-network based graph embedding generation and comparison system. A novel bi-directional code graph embedding generation has been proposed to enrich the information extracted from code graph. Furthermore, by deploying matrix manipulation, the throughput of the system has significantly increased for embedding generation. Potential applications such as executable file similarity calculation, vulnerability search are also presented in this invention. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198312 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/148 (20190101) Original (OR) Class G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6215 (20130101) G06K 9/6247 (20130101) G06K 9/6296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080392 | Bennett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Juan Carlos Bennett (Temecula, California); Mamadou H. Diallo (Santee, California) |
| ABSTRACT | A method for systematic collection and analysis of forensic data in a unified communications system deployed in a cloud environment. Three primary forensic components, namely, evidence collectors, a forensic controller and self-forensic investigators, are utilized in the method to interface with the components of the cloud environment and of the unified communications network. The method invokes a cloud evidence collection process which collects footprint data structures continuously at runtime to enable effective real-time collection of cloud forensic evidence and a cloud evidence analyzing process which generates evidence data that can be consumed by standard forensics tools. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/508103 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/1734 (20190101) G06F 21/552 (20130101) Original (OR) Class G06F 21/554 (20130101) G06F 21/566 (20130101) G06F 21/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080431 | Casto et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Matthew J Casto (Beavercreek, Ohio); Waleed Khalil (Dublin, Ohio); Brian Dupaix (Columbus, Ohio) |
| ABSTRACT | Method and apparatus for authenticating analog mixed-signal integrated circuits using process-specific functions (PSF) comprising: presenting wafer having plurality of dies, each die having circuit with identical design but having inherent physical differences due to process variation in their manufacture, each circuit designed to enhance the effects of the inherent differences; defining selected number of inputs/stimuli for authenticating and identifying each integrated circuit; defining expected response for each circuit, wherein the expected response for each circuit is the same due to the identical design; defining statistical window for analog response by the circuit to the inputs/stimuli; applying the inputs/stimuli to each circuit; receiving analog response corresponding to the applied inputs/stimuli, wherein the analog response falls outside statistical window when there are functional or physical changes to the circuit; separating from plurality of dies each die providing a response outside the statistical window, wherein only identified/authenticated dies remain. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/729873 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/44 (20130101) G06F 21/73 (20130101) Original (OR) Class G06F 21/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080451 | Slutzky et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Barry Slutzky (Williams, Indiana); Patrick Shaffer (Bloomington, Indiana) |
| ABSTRACT | A method and apparatus for simulating radio frequency propagation paths between radio frequency devices are provided. In an illustrative embodiment, the apparatus comprising a system controller for receiving and processing test data, a data sequencer configured to interact with attenuators and RF devices, and RF paths designed to simulate RF propagation paths. The method comprising steps to execute a multiple propagation path simulation based on various inputs including attenuators and electromagnetic environment inputs in accordance with various embodiments. |
| FILED | Saturday, August 11, 2018 |
| APPL NO | 16/101423 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 30/367 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080452 | Slutzky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Barry Slutzky (Williams, Indiana); Patrick Shaffer (Bloomington, Indiana) |
| ABSTRACT | A method and apparatus for simulating radio frequency propagation paths between radio frequency devices are provided. In an illustrative embodiment, the apparatus comprising a system controller for receiving and processing test data, a data sequencer configured to interact with attenuators and RF devices, and RF paths designed to simulate RF propagation paths. The method comprising steps to execute a full simulation. |
| FILED | Sunday, August 12, 2018 |
| APPL NO | 16/101469 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 30/367 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080821 | Cooke et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Cheryl Ann Cooke (San Diego, California); Steven Patrick Murphy (San Diego, California); Kris Gibson (Sykesville, Maryland) |
| ABSTRACT | A method for generating stereoscopic imagery comprising the steps of building an automated benthic ecology system comprising a high-resolution still camera, a high-resolution video camera, an environmental sensor package, a stereoscopic camera, and underwater housing, wherein the high-resolution video camera is configured for constant recording, turning the video camera on and hovering the ABES at the desired depth for a specific period of time acquiring imagery, wherein the imagery is automatically time-stamped with a date and time, extracting frames from the video, matching the timestamps on the photographs with the timestamps of the ROV log, which provides latitude, longitude and depth measurements, georeferencing each image using GeoSetter software, stitching imagery from the stereoscopic camera into a panoramic image using software. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367679 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/18 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) Original (OR) Class G06T 7/60 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/23238 (20130101) H04N 13/156 (20180501) H04N 13/204 (20180501) H04N 2005/2255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080828 | Fleizach |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gregory Knowles Fleizach (San Diego, California) |
| ABSTRACT | Method and system for improved contrast enhancement. The method includes receiving, from at least one imaging system, first and second component chiral images, the first component chiral image being captured by a first filter that is polarized in a first direction, the second component chiral image being captured by a second filter that is polarized in a second direction, the second direction being substantially orthogonal to the first direction. The method also includes pre-enhancing, by a processor, one or both of said first component chiral image and said second component chiral image. Then the processor weights and sums at least a portion of the first and second component chiral images. Weighting and summing may be repeated until an optimal weight is reached. A contrast enhanced image may be generated after the optimal weight is reached. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738871 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/007 (20130101) Original (OR) Class G06T 5/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080867 | Davis |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES of AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Austin V Davis (Clinton, Mississippi) |
| ABSTRACT | In one embodiment, an infrared camera generates thermal images and a computer generates track trees for volant targets (e.g., bats) detected in the images using an HKUF technique and detection filtering. The computer extends each track tree by adding new branches for each target detected in a subsequent image, generates motion metrics for each new branch, applies biologically informed motion constraints to the motion metrics to delete branches from the track trees, selects a track in each terminated track tree as a most likely track for the corresponding detected target using a track-scoring system based on a combination of track tortuosity and Kalman prediction errors, automatically generates a counting box based on density plots generated using the selected tracks, and calculates a census of the volant targets based on the selected tracks relative to the counting box. The technique handles targets that may be occluded for one or more images. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/239399 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 29/005 (20130101) Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 31/002 (20130101) Image Data Processing or Generation, in General G06T 7/277 (20170101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/30242 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081250 | Harmon et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Amber Lynn Harmon (Sanford, Maine); Ellen Marie Galvin (Dover, New Hampshire) |
| ABSTRACT | Apparatuses and methods for securely storing radioactive source materials that enables inventory activities with security functions. In particular, apparatuses and methods for securely storing radioactive source materials are provided with visual and automated inventory, security, alerting, and stabilization design elements that enable various inventory tasks, prevent storage structures from being negligently left open or unlocked, ensure stabilization of storage structures in a moving mobile structure, and provide an alerting system for warning staff of an unsecure or unlocked condition of such storage structures. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273823 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Tables; Desks; Office Furniture; Cabinets; Drawers; General Details of Furniture A47B 81/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/015 (20130101) G21F 5/125 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081252 | Russo et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John A. Russo (Spencerville, Maryland); Marc S. Litz (Columbia, Maryland); William B. Ray, II (Lubbock, Texas) |
| ABSTRACT | An electrophoretic deposition (EPD) process forms a radioluminescent phosphor and radioisotope composite layer on a conductive surface of a substrate. In the composite layer formed, the particles of radioisotope are homogeneously dispersed with the radioluminescent phosphor. The radioisotope may be a beta-emitter, such as Ni-63, H-3, Pm-147, or Sr-90/Y-90. By applying the composite layer using the EPD process, the electrode can be configured for betavoltaic, beta-photovoltaic and photovoltaic cells according to further embodiments. A direct bandgap semiconductor device can convert betas and/or photons emitted from composite layer. Methods and choice of materials and components produces a hybrid radioisotope battery, conversion of photons and nuclear decay products, or radioluminescent surfaces. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366792 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/02 (20130101) C25D 13/22 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 3/02 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) H01L 31/075 (20130101) H01L 31/1884 (20130101) H01L 31/03046 (20130101) H01L 31/03048 (20130101) H01L 31/022475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081555 | Rajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Siddharth Rajan (Columbus, Ohio); Zhanbo Xia (Columbus, Ohio); Caiyu Wang (Columbus, Ohio) |
| ABSTRACT | Dielectric super-junction transistors use combinations high dielectric relative permittivity materials and high-mobility materials. An associated electronic device includes a junction portion of a barrier layer adjacent a gate contact and a drain contact. A layered semiconductor device is configured with a junction dielectric permittivity that is greater than a channel dielectric permittivity in the channel layer. The junction portion has a dielectric structure that polarizes carriers within the junction portion such that excess charge on the gate is compensated by an opposite charge in the junction portion of the barrier layer proximate the gate. A sheet charge in the barrier layer is increased to form a depletion region with the channel layer that avoids a conductive parallel channel in the barrier layer to the drain contact. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/455736 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/408 (20130101) Original (OR) Class H01L 29/517 (20130101) H01L 29/872 (20130101) H01L 29/4908 (20130101) H01L 29/7786 (20130101) H01L 29/7788 (20130101) H01L 29/8611 (20130101) H01L 29/8613 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081722 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Navitas Systems, LLC (Woodridge, Illinois) |
| ASSIGNEE(S) | Navitas Systems, LLC (Lisle, Illinois) |
| INVENTOR(S) | Pu Zhang (Ann Arbor, Michigan); Michael Wixom (Ann Arbor, Michigan); Qingliu Wu (Ann Arbor, Michigan) |
| ABSTRACT | Provided are electrode active materials that include a metal oxide or oxynitride with a porous structure that when loaded with sulfur serve as electrochemically superior cathode active materials. The metal nitride or metal oxynitride structures are optionally used on their own, are coated with another material, or itself coats another porous structure such as a porous carbon structure that allows for excellent retention of both sulfur and polysulfides, are conductive themselves, and show long term stability and excellent cycle life. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/756384 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/808 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081851 | Marciante et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | John R. Marciante (Webster, New York); Jordan P. Leidner (Rochester, New York) |
| ABSTRACT | An optical fiber, such as in some instances a high-power, diode-pumped, dual-clad, ytterbium-doped fiber amplifier (YDFAs), having a fundamental mode and at least one higher order mode, wherein the higher order mode or modes have mode areas that are substantially larger than a mode area of the fundamental mode. |
| FILED | Thursday, July 20, 2017 |
| APPL NO | 16/318396 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0281 (20130101) G02B 6/02009 (20130101) G02B 6/02023 (20130101) G02B 6/02047 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0672 (20130101) Original (OR) Class H01S 3/1618 (20130101) H01S 3/06708 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082127 | Wynn et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Charles Wynn (Groton, Massachusetts); Yaron Rachlin (Newton, Massachusetts); Ryan Sullenberger (Somerville, Massachusetts); Sumanth Kaushik (Belmont, Massachusetts) |
| ABSTRACT | The ability to communicate with a specific subject at a prescribed location who lacks any communications equipment opens up many intriguing possibilities. Communications across noisy rooms, hail and warn applications, and localized communications directed at only the intended recipient are a few possibilities. We disclose and show localized acoustic communications, which we call photoacoustic communications, with a listener at long standoff distances using a modulated laser transmitted toward the receiver's ear. The optically encoded information is converted into acoustic messages via the photoacoustic effect. The photoacoustic conversion of the optical information into an audible signal occurs via the absorption of the light by ambient water vapor in the near area of the receiver's ear followed by airborne acoustic transmission to the ear. The recipient requires no external communications equipment to receive audible messages. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736212 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082347 | Dearth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nvidia Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Nvidia Corporation (Santa Clara, California) |
| INVENTOR(S) | Glenn Dearth (Santa Clara, California); Nan Jiang (Santa Clara, California); John Wortman (Santa Clara, California); Alex Ishii (Santa Clara, California); Mark Hummel (Santa Clara, California); Rich Reeves (Santa Clara, California) |
| ABSTRACT | Multiple processors are often used in computing systems to solve very large, complex problems, such as those encountered in artificial intelligence. Such processors typically exchange data among each other via an interconnect fabric (such as, e.g., a group of network connections and switches) in solving such complex problems. The amount of data injected into the interconnect fabric by the processors can at times overwhelm the interconnect fabric preventing some of the processors from communicating with each other. To address this problem, techniques are disclosed to enable, for example, processors that are connected to an interconnect fabric to coordinate and control the amount of data injected so that the interconnect fabric does not get overwhelmed. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277349 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/16 (20130101) H04L 43/0888 (20130101) H04L 47/18 (20130101) H04L 47/39 (20130101) H04L 47/127 (20130101) Original (OR) Class H04L 47/263 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082447 | Camp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | L. Jean Camp (Bloomington, Indiana) |
| ABSTRACT | A system comprising a processor in electrical communication with a network and a non-transitory memory having instructions that, in response to an execution by the processor, cause the processor to monitor a routing information base (“RIB”) of the network, identify a change in the RIB, calculate a probability of suspiciousness of the change in the RIB, and classify the change in the RIB based on a continuum of trust are disclosed. Methods of managing routers are also disclosed. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999673 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1466 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082450 | Eskridge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts); Florida Institute of Technology, Inc. (Melbourne, Florida) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts); Florida Institute of Technology, Inc. (Melbourne, Florida) |
| INVENTOR(S) | Thomas C. Eskridge (Satellite Beach, Florida); Marco M. Carvalho (Satellite Beach, Florida); Brett Benyo (Ayer, Massachusetts); Michael Atighetchi (Framingham, Massachusetts); Fusun Yaman (Arlington, Massachusetts) |
| ABSTRACT | A decision engine includes: a genetic algorithm framework including a knowledge base of standard configurations, a candidate selector generator and a selector to select a candidate configuration from a plurality of preferred standard configurations in response to the candidate selector generator; a parallelized reasoning framework including an attack surface reasoning algorithm module to compute the security and cost tradeoffs of an attack surface associated with each candidate configuration; and a user interface framework including a web service engine where users can interact and provide feedback on direction of an evolution used in a genetic algorithm search for evolving defenses. |
| FILED | Friday, April 20, 2018 |
| APPL NO | 15/958357 |
| ART UNIT | 2451 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2423 (20190101) Computer Systems Based on Specific Computational Models G06N 3/126 (20130101) G06N 5/022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/08 (20130101) H04L 41/22 (20130101) H04L 63/20 (20130101) Original (OR) Class H04L 63/1433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082763 | Brown |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher A Brown (Bloomington, Indiana) |
| ABSTRACT | The present invention relates to a communication disruption system. In a first audio path, a microphone receives input sound, an amplifier system amplifies the sound, and a sound system transmits a first output sound. In a second audio path, the microphone receives input sound, a delay circuit delays the sound, the amplifier system amplifies the sound, and the sound system transmits a second output sound. A target speaker will hear the first and second output sounds, with the first output sound being a reproduction of their speech heard nearly simultaneously with the original speech, and the second output sound being a reproduction of their speech heard slightly after the original speech. Due to the delayed auditory feedback effect, the target speaker's concentration will be disrupted, making it difficult for them to continue speaking. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/718783 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/04 (20130101) Original (OR) Class H04R 3/04 (20130101) H04R 29/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D926662 | Guild et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jennifer A Guild (Poulsbo, Washington); Eric E Seeley (Seabeck, Washington); Jose M Ruiz (Bremerton, Washington) |
| ABSTRACT | |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 29/742132 |
| ART UNIT | 2917 — Design |
| CURRENT CPC | Transportation D12/308 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11077327 | Sava Gallis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Dorina F. Sava Gallis (Albuquerque, New Mexico); Mark D. Tucker (Albuquerque, New Mexico); Mark K. Kinnan (Albuquerque, New Mexico); Jeffery A. Greathouse (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to a metal-organic framework composition, as well as constructs and methods thereof. In one particular example, the composition is employed to degrade a chemical agent in a non-aqueous environment. |
| FILED | Tuesday, November 27, 2018 |
| APPL NO | 16/201224 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/30 (20130101) Original (OR) Class A62D 2101/02 (20130101) A62D 2101/26 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1691 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077418 | Wegeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Robert S. Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Shankar Krishnan (Wilsonville, Oregon); Steven D. Leith (Albany, Oregon); Daniel R. Palo (Chisholm, Minnesota); Robert A. Dagle (Richland, Washington) |
| ABSTRACT | A solar thermochemical processing system is disclosed. The system includes a first unit operation for receiving concentrated solar energy. Heat from the solar energy is used to drive the first unit operation. The first unit operation also receives a first set of reactants and produces a first set of products. A second unit operation receives the first set of products from the first unit operation and produces a second set of products. A third unit operation receives heat from the second unit operation to produce a portion of the first set of reactants. |
| FILED | Tuesday, April 10, 2018 |
| APPL NO | 15/950068 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Original (OR) Class B01J 2219/00006 (20130101) B01J 2219/089 (20130101) B01J 2219/00159 (20130101) B01J 2219/0883 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/48 (20130101) C01B 3/384 (20130101) C01B 2203/061 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) C01B 2203/0445 (20130101) C01B 2203/0855 (20130101) C01B 2203/1288 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/30 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 3/04 (20130101) Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 3/188 (20130101) Methods of Steam Generation; Steam Boilers F22B 1/006 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0612 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/129 (20151101) Y02P 20/133 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 137/8593 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077477 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Qiang Zeng (Evanston, Illinois); Kornel Ehmann (Evanston, Illinois); Man Kwan Ng (Evanston, Illinois); Jian Cao (Wilmette, Illinois) |
| ABSTRACT | A rolling mill system for Incremental rotary shaping of an elongated workpiece is provided that includes first and second workpiece holders. A support frame has a track with the first and second workpiece holders being movably associated with the track, the workpiece holders and an associated workpiece being movable in unison along the track. A radial chuck is mounted to the frame that includes a plurality of jaws that are movable radially inwardly and outwardly. Each jaw has a tool mounted thereto that is rotatable about an axis of rotation, with the axis of rotation of each tool being oriented at a skew angle relative to the longitudinal axis of a workpiece. A source of electric current and an electrically conductive flow path are provided for flowing electrical current through a workpiece. A controller is provided that is configured to control the operation of each of the first motor, second motor and third motor, and to control the flow of current flowing through the tools to the workpiece. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 16/341163 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Rolling of Metal B21B 1/20 (20130101) B21B 19/06 (20130101) B21B 35/06 (20130101) B21B 37/46 (20130101) Original (OR) Class B21B 39/02 (20130101) B21B 2203/26 (20130101) B21B 2267/06 (20130101) B21B 2275/04 (20130101) B21B 2275/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077625 | Matsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Marc R. Matsen (Seattle, Washington); Mark A. Negley (Bellevue, Washington); William Preston Geren (Shoreline, Washington); Robert Miller (Fall City, Washington) |
| ABSTRACT | Thermoplastic welding apparatus and related methods are disclosed. An example method includes providing a smart susceptor between composite parts that are to be joined via thermoplastic welding. The example method includes positioning the composite parts and the smart susceptor on a tooling surface within a cavity of a tooling apparatus and applying a seal to the composite parts and the tooling surface to form a vacuum chamber between the composite parts and the tooling surface at a welding joint of the composite parts; producing a magnetic field at the welding joint. The example method includes providing a vacuum in the vacuum chamber during a welding operation. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411589 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/3612 (20130101) B29C 65/3644 (20130101) B29C 65/3668 (20130101) B29C 65/3676 (20130101) Original (OR) Class B29C 66/41 (20130101) B29C 66/00145 (20130101) B29C 66/474 (20130101) B29C 66/524 (20130101) B29C 66/721 (20130101) B29C 66/1122 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7392 (20130101) B29C 66/7394 (20130101) B29C 66/8122 (20130101) B29C 66/8122 (20130101) B29C 66/8126 (20130101) B29C 66/73921 (20130101) B29C 66/81457 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2307/04 (20130101) B29K 2309/08 (20130101) B29K 2905/12 (20130101) B29K 2909/02 (20130101) B29K 2995/0008 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/105 (20130101) H05B 2206/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077812 | Rodgers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); CONTINENTAL STRUCTURAL PLASTICS, INC. (Auburn Hills, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); CONTINENTAL STRUCTURAL PLASTICS, INC (Auburn Hills, Michigan) |
| INVENTOR(S) | William R. Rodgers (Bloomfield Township, Michigan); Venkateshwar R. Aitharaju (Troy, Michigan); Terrence Wathen (Sterling Heights, Michigan); Yutaka Yagi (West Bloomfield, Michigan) |
| ABSTRACT | An energy-absorbing assembly includes a housing and a plurality of discrete energy-absorbing elements. The housing includes a first wall and a second wall. The first wall and the second wall are spaced apart from one another to at least partially define an interior compartment. Each element of the plurality of energy-absorbing elements includes a polymer and a plurality of reinforcing fibers. The plurality of energy-absorbing elements is at least partially disposed within the interior compartment and fixed to the housing. Each energy-absorbing element of the plurality of energy-absorbing elements includes an elongated hollow structure extending between a first end and a second end. Each elongated hollow structure defines a longitudinal axis extending nonparallel to at least one of the first wall and the second wall. In various alternative aspects, each energy-absorbing element may include a transverse wall. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 15/907036 |
| ART UNIT | 3612 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 19/18 (20130101) Original (OR) Class B60R 2019/1893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078244 | Zamora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Paul Zamora (Gaithersburg, Maryland); Brent Lee Atkinson (Highlands Ranch, Colorado); Xinhua Lin (Plainview, New York); Louis A. Pena (Poquott, New York) |
| ABSTRACT | A composition comprising a synthetic growth factor analogue comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/358343 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/16 (20130101) A61L 27/16 (20130101) A61L 27/22 (20130101) A61L 27/24 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/227 (20130101) A61L 27/507 (20130101) A61L 2430/02 (20130101) Peptides C07K 14/51 (20130101) C07K 14/4705 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 27/18 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078432 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| INVENTOR(S) | Bin Yang (Pullman, Washington); Hongliang Wang (Pullman, Washington) |
| ABSTRACT | Bimetallic catalysts for the hydrodeoxygenation (HDO) conversion of lignin into useful hydrocarbons are provided. The catalysts are bifunctional bimetallic ruthenium catalysts Ru-M/X+Y comprising a metal M such as iron (Fe), nickel (Ni), copper (Cu) or zinc (Zn), zeolite Y and cation X+ (e.g. H+) associated with zeolite Y. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990077 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/088 (20130101) B01J 29/126 (20130101) B01J 29/146 (20130101) B01J 35/1023 (20130101) B01J 35/1038 (20130101) B01J 35/1061 (20130101) B01J 37/0201 (20130101) B01J 2229/186 (20130101) Acyclic or Carbocyclic Compounds C07C 1/22 (20130101) C07C 1/22 (20130101) C07C 1/22 (20130101) C07C 13/18 (20130101) C07C 13/18 (20130101) C07C 13/28 (20130101) C07C 13/28 (20130101) C07C 2523/06 (20130101) C07C 2523/46 (20130101) C07C 2523/72 (20130101) C07C 2523/78 (20130101) C07C 2523/89 (20130101) C07C 2523/745 (20130101) C07C 2523/755 (20130101) C07C 2529/12 (20130101) C07C 2529/14 (20130101) C07C 2601/14 (20170501) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/44 (20130101) C10G 3/45 (20130101) C10G 3/49 (20130101) C10G 3/50 (20130101) C10G 45/06 (20130101) C10G 45/12 (20130101) Original (OR) Class C10G 2300/202 (20130101) C10G 2300/1014 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/10 (20130101) C10L 1/1691 (20130101) C10L 2200/0469 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078499 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Harry R. Beller (Berkeley, California); Andria V. Rodrigues (Oakland, California); Kamrun Zargar (Rocklin, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Harry R. Beller (Berkeley, California); Andria V. Rodrigues (Oakland, California); Kamrun Zargar (Rocklin, California) |
| ABSTRACT | The present invention provides for a genetically modified host cell comprising a first polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase, and having an enzymatic activity to decarboxylate a phenylacetic acid into a toluene and a carbon dioxide, and a second polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase activating enzyme, and having an enzymatic activity to cleave a S-adenosylmethionine (SAM) to form a methionine and a 5′-deoxyadenosyl radical. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/286411 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/38 (20130101) C12N 9/14 (20130101) C12N 15/79 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078582 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher J Chang (Berkeley, California); Ming Gong (San Pablo, California); Zhi Cao (Albany, California); Wei Liu (Oxford, Ohio) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher J Chang (Berkeley, California); Ming Gong (San Pablo, California); Zhi Cao (Albany, California); Wei Liu (Oxford, Ohio) |
| ABSTRACT | The present invention provides for a composition comprising a heterostructure capable of electrochemical CO reduction to a carbon-carbon product, comprising an inorganic material and a porous molecule. In some embodiments, the heterostructure comprises the following structure: |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/116822 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 2219/0892 (20130101) Acyclic or Carbocyclic Compounds C07C 1/10 (20130101) C07C 1/10 (20130101) C07C 11/04 (20130101) C07C 29/159 (20130101) C07C 29/159 (20130101) C07C 31/04 (20130101) C07C 51/10 (20130101) C07C 51/10 (20130101) C07C 53/08 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) C07D 487/22 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 11/075 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078584 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alcoa USA Corp. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | ALCOA USA CORP. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xinghua Liu (Murrysville, Pennsylvania) |
| ABSTRACT | In some embodiments, an exemplary electrolytic cell includes: a cathode structure disposed within an electrolysis cell, wherein the electrolysis cell is configured to produce metal on a surface of the cathode structure, wherein the cathode structure is configured to fit along a floor of the electrolysis cell, wherein the cathode structure has a sloped surface when compared to a generally horizontal plane, and wherein via the sloped surface, the cathode structure is configured to drain a metal product from the sloped surface towards a lower end of the cathode structure. |
| FILED | Monday, April 02, 2018 |
| APPL NO | 15/943171 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/12 (20130101) Original (OR) Class C25C 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078867 | Sellnau |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (, None) |
| INVENTOR(S) | Mark C. Sellnau (Bloomfield Hills, Michigan) |
| ABSTRACT | A piston for use in a GDCI engine cooperates with the wall of a cylinder defined in the engine and with a cylinder head to define a combustion chamber. The surface of the piston that faces the cylinder head defines a bowl that is configured to receive fuel that is dispensed from a fuel injector that is located in the cylinder head substantially along the central axis of the cylinder. The bowl is configured such that substantially all of the injected fuel associated with a combustion event reaches a localized equivalence ratio greater than 0.0 and less than or equal to 1.2 at a time immediately preceding initiation of the combustion event. |
| FILED | Wednesday, April 16, 2014 |
| APPL NO | 14/784680 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 1/12 (20130101) F02B 3/06 (20130101) F02B 17/005 (20130101) F02B 23/06 (20130101) F02B 23/0696 (20130101) F02B 2023/102 (20130101) Controlling Combustion Engines F02D 2041/3052 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/28 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 10/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079068 | Jayaraman et al. |
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| FUNDED BY |
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| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Ambalavanan Jayaraman (Highlands Ranch, Colorado); Michael Travis Bonnema (Arvada, Colorado) |
| ABSTRACT | A method for rapidly filling a compressed gas storage tank with a moderated temperature rise using a Coanda nozzle to inject the feed gas into the tank and using the Coanda nozzle to direct the feed gas along the inner surface of the storage tank; entraining the stored gas with the feed gas that is flowing under the influence of the Coanda effect to flow along the inner surface of the gas storage tank; and transferring heat from the flowing gas to the external walls of the tank. Also, a compressed gas storage tank for rapid filling with a moderated temperature rise comprising: a gas storage tank and a Coanda nozzle capable of directing feed gas that is injected into the gas storage tank along the inner surface of the gas storage tank. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989815 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/06 (20130101) Original (OR) Class F17C 13/026 (20130101) F17C 2201/0109 (20130101) F17C 2221/012 (20130101) F17C 2250/043 (20130101) F17C 2250/0439 (20130101) F17C 2265/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079130 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Danny Parker (Orlando, Florida); Eric Martin (Orlando, Florida); Karen Fenaughty (Orlando, Florida); David A. Chasar (Orlando, Florida) |
| ABSTRACT | A smart ventilation system which uses outdoor temperature and moisture to optimize control of the system. The main principle is to shift ventilation from time periods that have large indoor-outdoor temperature and moisture differences to periods when these differences are smaller, and their energy and comfort impacts are expected to be less. Fan flow rates are reduced when the outside temperature and moisture falls outside of optimum levels, yet overall air exchange is maintained to ensure chronic and acute exposure to pollutants remains relative to best practice. Online weather and smart thermostat data can be used as control inputs, so no specific measurement devices are needed to control ventilation fans. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571986 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 7/007 (20130101) F24F 11/30 (20180101) Original (OR) Class F24F 11/64 (20180101) F24F 11/65 (20180101) F24F 13/08 (20130101) F24F 2110/10 (20180101) F24F 2110/12 (20180101) F24F 2110/20 (20180101) F24F 2110/22 (20180101) F24F 2120/10 (20180101) F24F 2130/10 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079287 | Gabet Hoffmeister et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Steven F. Son (West Lafayette, Indiana); Eric R. Westphal (West Lafayette, Indiana) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Kathryn N. Gabet Hoffmeister (Albuquerque, New Mexico); Enrico C. Quintana (Albuquerque, New Mexico); Walter Gill (Albuquerque, New Mexico); Steven F. Son (West Lafayette, Indiana); Eric R. Westphal (West Lafayette, Indiana) |
| ABSTRACT | A method and system for determining temperature are provided. The method comprises using an x-ray source to irradiate a sample of a material with x-rays. Photon fluorescence produced by the sample in response to the x-ray irradiation is detected by a number of photon detectors. Based on the detected fluorescence a temperature of the sample is determined according to a predetermined relationship between photon fluorescence and temperature for the material. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/662669 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/30 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) G01N 2223/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079366 | Klein et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Levente Klein (Tuckahoe, New York); Theodore van Kessel (Millbrook, New York); Ramachandran Muralidhar (Mahopac, New York); Michael A. Schappert (Wappingers Falls, New York) |
| ABSTRACT | Embodiments of the invention are directed to an integrated sensing system that includes a movable orientation device configured to dynamically position the movable orientation device based on receiving an air-flow. A gas sensor is coupled to the movable orientation device. The gas sensor includes a recognition element configured to detect a chemical in a plume. The movable orientation device is configured to perform a synchronized sensing operation that includes, based at least in part on the movable orientation device receiving the air-flow, moving the movable orientation device to dynamically maintain a predetermined orientation of the movable orientation device relative to a direction of the air-flow. The predetermined orientation includes positioning the gas sensor in a path of the air-flow, wherein the air-flow is influencing the plume to move along the path such that the recognition element is exposed to the plume. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923118 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) G01M 3/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2273 (20130101) G01N 33/0073 (20130101) Original (OR) Class G01N 2033/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079412 | Laughlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daric Gray Laughlin (Overland Park, Kansas); Christopher Scott Marchman (Overland Park, Kansas) |
| ABSTRACT | An optical current monitor for detecting a current traveling through conductive material. The optical current monitor comprises a light source for emitting light at an output level; a lens configured to receive the light; Faraday material positioned near the conductive material and configured to receive light that has passed through the lens, thereby producing rotated light; a polarizer configured to polarize the rotated light; a photodetector configured to receive the rotated light and output a signal as a function of the rotated light; and a feedback system. The feedback system is configured to receive the signal from the photodetector and modify the output level of the light source based on the signal so that the signal remains at a reference level when the current is not traveling through the conductive material. |
| FILED | Thursday, January 10, 2019 |
| APPL NO | 16/244317 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/246 (20130101) Original (OR) Class G01R 19/0092 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/09 (20130101) G02F 1/0036 (20130101) G02F 1/0136 (20130101) G02F 2201/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079504 | Scates |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Wade Scates (Idaho Falls, Idaho) |
| ABSTRACT | A neutron spectrum generator is disclosed herein including a neutron source, a scatterer positioned in a direct path between the neutron source and a neutron detector, and a material shell configured to have at least one non-uniform characteristic selected from the group consisting of a material, a thickness, a length, an angle, a layer, and combinations thereof to generate a specific spectrum at the neutron detector that is different than the spectrum of the neutron source. A related method includes measuring a first response generated by a first material shell of a neutron spectrum generator interacting with a neutron source, replacing the first material shell with a second material shell, measuring a second response generated by a second material shell of a neutron spectrum generator interacting with the neutron source, and determining a total fission response by determining a difference between the first response and the second response. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971767 |
| ART UNIT | 2896 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/065 (20130101) G01T 3/085 (20130101) G01T 7/005 (20130101) Original (OR) Class Conversion of Chemical Elements; Radioactive Sources G21G 4/02 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079505 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico); CHEVRON U.S.A. INC. (San Ramon, California) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico); CHEVRON U.S.A. INC. (San Ramon, California) |
| INVENTOR(S) | Paul A. Johnson (Santa Fe, New Mexico); Timothy J. Ulrich, II (Los Alamos, New Mexico); Pierre-Yves Le Bas (Los Alamos, New Mexico); Robert A. Guyer (Los Alamos, New Mexico); Harvey E. Goodman (Houston, Texas); Marcel C. Remillieux (Los Alamos, New Mexico) |
| ABSTRACT | Apparatus (10) and methods for combining time reversal and elastic nonlinearity of formation materials for qualtitatively probing for over-pressured regions down hole in advance of a well drilling bit, to determine the distance to the over-pressured region, and for accurately measuring pore pressure downhole in a formation, are described. Classical and reciprocal time reversal methods may be utilized to achieve these measurements. |
| FILED | Thursday, March 09, 2017 |
| APPL NO | 16/083441 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/005 (20130101) Original (OR) Class G01V 1/48 (20130101) G01V 1/307 (20130101) G01V 2200/16 (20130101) G01V 2210/63 (20130101) G01V 2210/622 (20130101) G01V 2210/1216 (20130101) G01V 2210/6248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079543 | Britten et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jerald A. Britten (Clayton, California); Cindy C. Larson (Tracy, California); Hoang T. Nguyen (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jerald A. Britten (Clayton, California); Cindy C. Larson (Tracy, California); Hoang T. Nguyen (Livermore, California) |
| ABSTRACT | A method of fabricating a multilayer dielectric (MLD) diffraction grating by providing a multilayer stack having a grating layer, and anisotropically etching the grating layer to form grating lines having an initial lineheight, an initial linewidth, and an initial grating duty cycle, that are greater than a target lineheight, a target linewidth, and a target grating duty cycle, respectively. An isotropic wet etch solution is then used to etch back the grating lines to the target lineheight, the target linewidth, and the target grating duty cycle so as to minimize electric field intensities and maximize diffraction efficiency for a given set of MLD illumination conditions. |
| FILED | Friday, September 23, 2011 |
| APPL NO | 13/244033 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/136 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079649 | Ram et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNITED STATES DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Manoj Kumar Ram (Palm Harbor, Florida); D. Yogi Goswami (Tampa, Florida); Elias K. Stefanakos (Tampa, Florida) |
| ABSTRACT | The subject invention pertains to color changeable, film materials comprising a metal substrate layer; a conducting polymer or conducting polymer composite layer; and an electrolyte layer. The conducting polymer or conducting polymer composite layer of the film material is capable of exhibiting changes in one or more optical properties when the film material is in contact with a metal. The subject invention also pertains to methods of preparing conducting polymer films capable of exhibiting changes in optical properties. |
| FILED | Thursday, October 15, 2015 |
| APPL NO | 14/884201 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) G02F 1/153 (20130101) Original (OR) Class G02F 1/15165 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079745 | Giera |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Brian Giera (Oakland, California) |
| ABSTRACT | A system for rapidly adapting production of a product based on classification of production data using a classifier trained on prior production data is provided. A production control system includes a learning system and an adaptive system. The learning system trains a production classifier to label or classify previously collected production data. The adaptive system receives production data in real time and classifies the production data in real time using the production classifier. If the classification indicates a problem with the manufacturing of the product, the adaptive system controls the manufacturing to rectify the problem by taking some corrective action. The production classifier is trained using bootstrap data and corresponding example data extracted from prior production data. Once the bootstrap data is labeled, the corresponding example data is automatically labeled for use as training data. |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 14/952665 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/20 (20210101) B22F 10/30 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/0265 (20130101) G05B 19/41875 (20130101) Original (OR) Class G05B 2219/32018 (20130101) G05B 2219/33034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/20 (20190101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/02 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080196 | Bent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMC IP Holding Company LLC (Hopkinton, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | EMC IP Holding Company LLC (Hopkinton, Massachusetts); Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | John M. Bent (Los Alamos, New Mexico); Sorin Faibish (Newton, Massachusetts); Gary Grider (Los Alamos, New Mexico); Aaron Torres (Los Alamos, New Mexico); Jun He (Madison, Wisconsin) |
| ABSTRACT | Techniques are provided for pattern-aware prefetching using a parallel log-structured file system. At least a portion of one or more files is accessed by detecting at least one pattern in a non-sequential access of the one or more files; and obtaining at least a portion of the one or more files based on the detected at least one pattern. The obtaining step comprises, for example, a prefetching or pre-allocation of the at least the portion of the one or more files. A prefetch cache can store the portion of the one or more obtained files. The cached portion of the one or more files can be provided from the prefetch cache to an application requesting the at least a portion of the one or more files. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/716972 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0862 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081314 | Jungjohann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Katherine L. Jungjohann (Sandia Park, New Mexico); Khalid M. Hattar (Albuquerque, New Mexico) |
| ABSTRACT | An integrated transmission electron microscope comprising multiple electron sources for tuned beams of ultrafast, scanning probe, and parallel illumination in varied beam energies can be alternated within sub-microseconds onto a sample with dynamic ‘transient state’ processes to acquire atomic-scale structural/chemical data with site specificity. The various electron sources and condenser optics enable high-resolution imaging, high-temporal resolution imaging, and chemical imaging, using fast-switching magnets to direct the different electron beams onto a single maneuverable objective pole piece where the sample resides. Such multimodal in situ characterization tools housed in a single microscope have the potential to revolutionize materials science. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/035267 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/12 (20130101) H01J 37/28 (20130101) Original (OR) Class H01J 37/1477 (20130101) H01J 2237/063 (20130101) H01J 2237/2007 (20130101) H01J 2237/2802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081688 | Cui et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BD OF TRUSTEES OF THE LELAND STANFORD JR UNIV (Stanford, California) |
| INVENTOR(S) | Yi Cui (Stanford, California); Lei Liao (San Jose, California); Jiangyan Wang (Palo Alto, California) |
| ABSTRACT | A battery electrode is provided that includes a porous silicon microstructure precursor, a silicon shell coating deposited on the silicon microstructure precursor, and a graphene coating deposited on the silicon shell coating, where the graphene coating encapsulates the silicon shell coating forming a graphene-encapsulated silicon-shell-protected porous silicon microstructure precursor battery electrode. |
| FILED | Monday, March 18, 2019 |
| APPL NO | 16/356487 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/021 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/61 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/0471 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081932 | Post |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F. Post (Walnut Creek, California) |
| ABSTRACT | Robust electro-static (ES) device embodiments, with application to energy storage flywheels as an example, are described that provide reliable, high-efficiency operation in the presence of thermal and mechanical perturbations, as well as seismic events. Electro-static generators and motors, when augmented with magnetic bearings, passive three-dimensional stabilization techniques and dynamic touch-down bearings, enable robust performance in the face of these environmental concerns, as well as efficient operation during typical operational sequences, including spin-up and steady-state modalities. |
| FILED | Saturday, December 28, 2019 |
| APPL NO | 16/729317 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 15/315 (20130101) Dynamo-electric Machines H02K 7/025 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/002 (20130101) H02N 1/08 (20130101) H02N 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11076786 | Choudhury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sohini Roy Choudhury (Miami, Florida); Yogeswaran Umasankar (Homestead, Florida); Shekhar Bhansali (Weston, Florida); Robert S. Kirsner (Miami, Florida); Hadar A. Lev-Tov (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida); UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Sohini Roy Choudhury (Miami, Florida); Yogeswaran Umasankar (Homestead, Florida); Shekhar Bhansali (Weston, Florida); Robert S. Kirsner (Miami, Florida); Hadar A. Lev-Tov (Miami, Florida) |
| ABSTRACT | The subject invention provides sensor systems that can detect biomarkers related to wound healing (e.g., uric acid, adenosine, arginine and/or xanthine). In one embodiment, the subject invention pertains to materials and methods for monitoring biomarkers non-invasively in a wound and a biofluid (e.g., sweat) in the proximity of the wound, optionally, including other physiological fluids. Skin based, non-invasive enzymatic electrochemical biosensor on a wearable platform (e.g., sweat patch) that can evaluate the healing of wounds through assessment of its biomarker levels are provided. This non-invasive detection from physiologically biofluids can reduce or eliminate occlusion effects. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 16/589437 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/20 (20130101) A61B 5/1486 (20130101) Original (OR) Class A61B 5/4266 (20130101) A61B 5/4277 (20130101) A61B 5/14507 (20130101) A61B 5/14539 (20130101) A61B 5/14546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077213 | Bawendi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi G. Bawendi (Cambridge, Massachusetts); Daniel K. Harris (Wilton, Connecticut); Oliver T. Bruns (Boston, Massachusetts); Thomas S. Bischof (Medford, Massachusetts) |
| ABSTRACT | InAs based core-shell particles which leads to tunable, narrow emitting semiconductor nanocrystals with a very high quantum yield which can be preserved in physiological buffers with long stability can used for short wavelength infrared (SWIR) imaging. Increased resolution with reduced read time and increased imaging frequency can provide advantages in in vivo applications. |
| FILED | Tuesday, April 22, 2014 |
| APPL NO | 14/258681 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/489 (20130101) A61B 5/02007 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0067 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/565 (20130101) C09K 11/883 (20130101) C09K 11/7492 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/40 (20130101) C30B 29/60 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/83 (20130101) Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11077227 | Kumta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Jingyao Wu (Pittsburgh, Pennsylvania); Oleg Velikokhatnyi (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery. |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 15/532149 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/30 (20130101) Original (OR) Class A61L 27/047 (20130101) A61L 27/54 (20130101) A61L 27/306 (20130101) A61L 31/16 (20130101) A61L 31/022 (20130101) A61L 31/082 (20130101) A61L 31/088 (20130101) A61L 2300/102 (20130101) Alloys C22C 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078148 | Cronin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Steve P. Cronin (Louisville, Kentucky); Craig A. Grapperhaus (Jeffersonville, Indiana); Robert M. Buchanan (Louisville, Kentucky); Jacob M. Strain (Louisville, Kentucky); Joshua M. Spurgeon (Louisville, Kentucky) |
| ABSTRACT | Some embodiments of the invention include methods of using a compound (e.g., Formula (I)) for the reduction of carbon dioxide to formate by contacting the carbon dioxide with a composition comprising a compound. In certain embodiments, the source of the carbon dioxide is air or is flue gas. Additional embodiments of the invention are also discussed herein. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 16/803027 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 2531/26 (20130101) B01J 2531/0238 (20130101) Acyclic or Carbocyclic Compounds C07C 51/41 (20130101) Original (OR) Class C07C 53/06 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 11/043 (20210101) C25B 11/057 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078214 | Gangjee |
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| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | The present invention provides a compound of Formula XXVII: wherein X is CH2 or O, and R1 is H or CH3; or a salt or a hydrate of the compound, and further provides a pharmaceutical composition comprising the compound of Formula XXVII and one or more acceptable pharmaceutical carriers. A method of treating a patient having cancer comprising administering a therapeutically effective amount of a compound of Formula XXVII, or a pharmaceutical composition comprising a compound of Formula XXVII and one or more acceptable pharmaceutical carriers to the patient is disclosed. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571842 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078333 | Pyun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Dong-Chul Pyun (Tucson, Arizona); Richard S. Glass (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona); Jared J. Griebel (Tucson, Arizona); Soha Namnabat (Tucson, Arizona) |
| ABSTRACT | Copolymerization of elemental sulfur with functional comonomers afford sulfur copolymers having a high molecular weight and high sulfur content. Nucleophilic activators initiate sulfur polymerizations at relative lower temperatures and in solutions, which enable the use of a wider range of comonomers, such as vinylics, styrenics, and non-homopolymerizing comonomers. Nucleophilic activators promote ring-opening reactions to generate linear polysulfide intermediates that copolymerize with comonomers. Dynamic sulfur-sulfur bonds enable re-processing or melt processing of the sulfur polymer. Chalcogenide-based copolymers have a refractive index of about 1.7-2.6 at a wavelength in a range of about 5000 nm-8μιτι. The sulfur copolymer can be a thermoplastic or a thermoset for use in elastomers, resins, lubricants, coatings, antioxidants, cathode materials for electrochemical cells, dental adhesives/restorations, and polymeric articles such as polymeric films and free-standing substrates. Optical substrates are constructed from the chalcogenide copolymer and are substantially transparent in the visible and infrared spectrum. |
| FILED | Wednesday, July 13, 2016 |
| APPL NO | 15/744398 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 2/38 (20130101) C08F 2/44 (20130101) C08F 2/44 (20130101) C08F 12/08 (20130101) C08F 12/08 (20130101) C08F 12/08 (20130101) C08F 12/30 (20130101) C08F 212/08 (20130101) C08F 228/02 (20130101) C08F 228/04 (20130101) C08F 228/06 (20130101) C08F 230/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/00 (20130101) C08G 75/14 (20130101) Original (OR) Class C08G 75/16 (20130101) C08G 79/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/06 (20130101) Compositions of Macromolecular Compounds C08L 81/00 (20130101) C08L 81/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/382 (20130101) H01M 4/602 (20130101) H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078359 | Rangari et al. |
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| FUNDED BY |
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| APPLICANT(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| ASSIGNEE(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| INVENTOR(S) | Vijaya Rangari (Tuskegee, Alabama); Boniface Tiimob (Tuskegee, Alabama) |
| ABSTRACT | A biopolymer blend is provided that comprises a combination of three components: poly (butylene adipate-co-terephthalate) (PBAT); agriculture sourced polylactic acid (PLA); and engineered proteinaceous eggshell nanoparticles. The two polymer components can be present in any ratio but an approximate 70:30 ratio is preferred. The engineered proteinaceous eggshell nanoparticles are preferably about 10-25 nanometers. Also provided are methods of preparing biopolymer film and packaging components. Pelleted poly (butylene adipate-co-terephthalate) and agriculture sourced polylactic acid (PLA) are dissolved in chloroform and mixed together to form a polymer blend, and engineered proteinaceous eggshell nanoparticles are incorporated into the polymer blend, which is then extruded to create a biopolymer film or component. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/040250 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2367/02 (20130101) C08J 2467/04 (20130101) C08J 2489/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/26 (20130101) C08K 7/00 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) C08K 2201/018 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 67/04 (20130101) Original (OR) Class C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 77/00 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101) C08L 2201/06 (20130101) C08L 2203/16 (20130101) C08L 2205/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078459 | Tourlomousis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Filippos Tourlomousis (Hoboken, New Jersey); Robert Chang (Wayne, New Jersey); Dilhan Kalyon (Teaneck, New Jersey) |
| ABSTRACT | Methods for the development and integration of multiple apparatuses and methods for achieving administration of stem cell therapies include precision manufacturing of tissue scaffolds and/or bioreactor substrates. The nano/microscale fiber material extrusion typifying the electrospinning process is married with the fiber alignment and layering characteristic of an additive manufacturing process. The method generates porous fibrous 3-D meshes with precision controlled structures from biopolymer melts and solutions and gels, blends, and suspensions with and without cells. A method of tracking the migration histories and shapes of stem cells on scaffold surfaces relies on immunofluorescent imaging and automated algorithms based on machine learning. The combination of the precision manufacturing method and the method of cell tracking and cell shape statistics, along with understanding of the intimate relationship between the cell shape/phenotype and scaffold architecture leads to an integrated method for cultivating and harvesting cells having desired phenotypes. |
| FILED | Wednesday, August 15, 2018 |
| APPL NO | 15/998685 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3834 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078698 | Lang et al. |
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| FUNDED BY |
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| APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Robert J. Lang (Alamo, California); Larry L. Howell (Orem, Utah); Spencer P. Magleby (Provo, Utah); Todd G. Nelson (Provo, Utah) |
| ABSTRACT | A hinged mechanism includes: panels; and hinges connecting respective pairs of the panels to each other in a closed loop so that the hinged mechanism is non-planar, wherein at least one of the hinges is a rolling-contact hinge. All of the hinges can be rolling-contact hinges. The closed-loop hinged mechanism can comprise at least four hinges, each of the at least four hinges being a sole connection between a respective adjacent pair of the panels. A cross section of rolling surfaces of the rolling-contact hinge can be circular. A cross section of rolling surfaces of the rolling-contact hinge can be non-circular. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/422195 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hinges or Suspension Devices for Doors, Windows or Wings E05D 1/00 (20130101) E05D 1/02 (20130101) E05D 1/04 (20130101) E05D 3/04 (20130101) E05D 3/06 (20130101) E05D 3/10 (20130101) Original (OR) Class E05D 3/122 (20130101) E05D 2003/025 (20130101) Technical Subjects Covered by Former US Classification Y10T 16/5474 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079130 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Danny Parker (Orlando, Florida); Eric Martin (Orlando, Florida); Karen Fenaughty (Orlando, Florida); David A. Chasar (Orlando, Florida) |
| ABSTRACT | A smart ventilation system which uses outdoor temperature and moisture to optimize control of the system. The main principle is to shift ventilation from time periods that have large indoor-outdoor temperature and moisture differences to periods when these differences are smaller, and their energy and comfort impacts are expected to be less. Fan flow rates are reduced when the outside temperature and moisture falls outside of optimum levels, yet overall air exchange is maintained to ensure chronic and acute exposure to pollutants remains relative to best practice. Online weather and smart thermostat data can be used as control inputs, so no specific measurement devices are needed to control ventilation fans. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/571986 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 7/007 (20130101) F24F 11/30 (20180101) Original (OR) Class F24F 11/64 (20180101) F24F 11/65 (20180101) F24F 13/08 (20130101) F24F 2110/10 (20180101) F24F 2110/12 (20180101) F24F 2110/20 (20180101) F24F 2110/22 (20180101) F24F 2120/10 (20180101) F24F 2130/10 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079214 | Zhou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | LEHIGH UNIVERSITY (, None) |
| INVENTOR(S) | Chao Zhou (Bethlehem, Pennsylvania) |
| ABSTRACT | Integrated photonic chips and related systems and methods suitable for space-division multiplexing optical coherence tomography scanning are disclosed. In one embodiment, the photonic chip comprises a substrate, an optical input port which receives an incident sampling beam from an external light source, a plurality of optical output ports configured to transmit a plurality of sampling beams from the chip to a sample to capture scanned images of the sample, and a plurality of interconnected and branched waveguide channels formed in the substrate. Waveguide channels in a splitter region divide the sampling beam into the plurality of sampling beams at the output ports. Terminal portions of the waveguide channels in a time delay region associated with each output port have different predetermined lengths to create an optical time delay between the sampling beams. In some embodiments, the chip further comprises an interferometer region to create interference patterns. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 16/612905 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 2562/0233 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) G01B 9/02019 (20130101) G01B 9/02028 (20130101) G01B 9/02051 (20130101) Original (OR) Class G01B 9/02091 (20130101) G01B 2290/65 (20130101) Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/2861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079412 | Laughlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daric Gray Laughlin (Overland Park, Kansas); Christopher Scott Marchman (Overland Park, Kansas) |
| ABSTRACT | An optical current monitor for detecting a current traveling through conductive material. The optical current monitor comprises a light source for emitting light at an output level; a lens configured to receive the light; Faraday material positioned near the conductive material and configured to receive light that has passed through the lens, thereby producing rotated light; a polarizer configured to polarize the rotated light; a photodetector configured to receive the rotated light and output a signal as a function of the rotated light; and a feedback system. The feedback system is configured to receive the signal from the photodetector and modify the output level of the light source based on the signal so that the signal remains at a reference level when the current is not traveling through the conductive material. |
| FILED | Thursday, January 10, 2019 |
| APPL NO | 16/244317 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/246 (20130101) Original (OR) Class G01R 19/0092 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/09 (20130101) G02F 1/0036 (20130101) G02F 1/0136 (20130101) G02F 2201/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079596 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Sheng Liu (San Jose, California) |
| ABSTRACT | An exemplary display is placed in an optical pathway extending from an entrance pupil of a person's eye to a real-world scene beyond the eye. The display includes at least one 2-D added-image source that is addressable to produce a light pattern corresponding to a virtual object. The source is situated to direct the light pattern toward the person's eye to superimpose the virtual object on an image of the real-world scene as perceived by the eye via the optical pathway. An active-optical element is situated between the eye and the added-image source at a location that is optically conjugate to the entrance pupil and at which the active-optical element forms an intermediate image of the light pattern from the added-image source. The active-optical element has variable optical power and is addressable to change its optical power to produce a corresponding change in perceived distance at which the intermediate image is formed, as an added image to the real-world scene, relative to the eye. |
| FILED | Wednesday, June 03, 2015 |
| APPL NO | 14/729195 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/004 (20130101) G02B 27/017 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 30/34 (20200101) G02B 2027/014 (20130101) G02B 2027/0127 (20130101) G02B 2027/0132 (20130101) G02B 2027/0134 (20130101) G02B 2027/0145 (20130101) G02B 2027/0147 (20130101) G02B 2027/0187 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 13/322 (20180501) H04N 13/344 (20180501) H04N 13/383 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079843 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Eakta Jain (Gainesville, Florida); Sanjeev Jagannatha Koppal (Gainesville, Florida); Brendan Matthew John (Gainesville, Florida) |
| ABSTRACT | Provided are methods, apparatuses, and systems for tracking a pupil of an eye of a user with degraded iris authentication accuracy. In certain examples, an eye tracking device includes a camera adapted to capture an eye image of at least one eye of a user. The eye tracking device further includes an image processor adapted to defocus the eye image in order to generate a defocused eye image. The defocused eye image comprises reduced iris authentication accuracy. The eye tracking device further includes a tracking processor configured to detect a pupil in the defocused eye image and determine a gaze direction of the user based at least in part on one or more of the defocused eye image and the pupil. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 16/911113 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 2027/0138 (20130101) G02B 2027/0178 (20130101) G02B 2027/0187 (20130101) Electric Digital Data Processing G06F 3/013 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080236 | Yin et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | DEEPBITS TECHNOLOGY INC. (Riverside, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Heng Yin (Riverside, California); Xunchao Hu (Riverside, California); Sheng Yu (Riverside, California); Yu Zheng (Riverside, California) |
| ABSTRACT | A novel high-throughput embedding generation and comparison system for executable code is presented in this invention. More specifically, the invention relates to a deep-neural-network based graph embedding generation and comparison system. A novel bi-directional code graph embedding generation has been proposed to enrich the information extracted from code graph. Furthermore, by deploying matrix manipulation, the throughput of the system has significantly increased for embedding generation. Potential applications such as executable file similarity calculation, vulnerability search are also presented in this invention. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198312 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/148 (20190101) Original (OR) Class G06F 17/16 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6215 (20130101) G06K 9/6247 (20130101) G06K 9/6296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11080526 | Khandelwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Ankush Khandelwal (Minneapolis, Minnesota); Anuj Karpatne (Minneapolis, Minnesota); Vipin Kumar (Minneapolis, Minnesota) |
| ABSTRACT | A method includes classifying low-resolution pixels of a low-resolution satellite image of a geographic area to form an initial classification map and selecting at least one physically-consistent classification map of the low-resolution pixels based on the initial classification map. A water level associated with at least one of the physically-consistent classification maps is then used to identify a set of high-resolution pixels representing a perimeter of water in the geographic area. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/103523 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) Original (OR) Class G06K 9/00651 (20130101) G06K 9/6202 (20130101) G06K 9/6255 (20130101) G06K 9/6267 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/55 (20170101) G06T 2207/10032 (20130101) G06T 2207/30188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11079343 | Klueg |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Klueg (Linwood, New Jersey) |
| ABSTRACT | An X-ray imaging system for reconstructing X-ray spectra includes an integrating detector and a measurement mask, including at least one physical filter, positioned between the integrating detector and an X-ray source spectrum. The integrating detector receives a masked X-ray spectrum after the source spectrum has been filtered in accordance with the measurement mask. As a result of the measurement mask containing one or more physical filters being combined, a measurement mask having energy band-pass regions can be generated, to cover the source spectrum. Measured data, based on the masked X-ray spectrum and characteristics of the measurement mask, is collected from the integrating detector. The X-ray imaging system reconstructs an X-ray spectrum and generates the reconstructed X-ray spectrum based on applying a predetermined algorithm, such as total variation minimization reconstruction, to the measured data. |
| FILED | Tuesday, January 26, 2021 |
| APPL NO | 17/158676 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/087 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11079369 | Deline |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | James E. Deline (Egg Harbor City, New Jersey) |
| ABSTRACT | Various embodiments of the present invention are directed towards a system and method to dispense an explosive compound onto a substrate. An example device includes a solvent having the explosive compound dissolved in the solvent to form a sample. A delivery mechanism dispenses the sample in a dispersed manner to sufficiently vaporize the solvent to prevent wicking while dispersing a residue of the explosive compound on the substrate to enable detection by explosive detection tools. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/037692 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 1/2813 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2001/2893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081331 | Russell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Zach Russell (Durham, North Carolina); Michael Gehm (Durham, North Carolina); Jeffrey T. Glass (Durham, North Carolina); Shane Di Dona (Durham, North Carolina); Evan Chen (Durham, North Carolina); Charles Parker (Durham, North Carolina); Jason Amsden (Durham, North Carolina); David Brady (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are mass spectrometers having segmented electrodes and associated methods. According to an aspect, an apparatus or mass spectrometer includes an ion source configured to generate ions from a sample. The apparatus also includes a detector configured to detect a plurality of mass-to-charge ratios associated with the ions. Further, the apparatus includes segmented electrodes positioned between the ion source and the detector. The apparatus also includes a controller configured to selectively apply a voltage across the segmented electrodes for forming a predetermined electric field profile. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/768595 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/322 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11082447 | Camp |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | L. Jean Camp (Bloomington, Indiana) |
| ABSTRACT | A system comprising a processor in electrical communication with a network and a non-transitory memory having instructions that, in response to an execution by the processor, cause the processor to monitor a routing information base (“RIB”) of the network, identify a change in the RIB, calculate a probability of suspiciousness of the change in the RIB, and classify the change in the RIB based on a continuum of trust are disclosed. Methods of managing routers are also disclosed. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999673 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1466 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11077607 | Snyder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Made In Space, Inc. (Moffett Field, California) |
| ASSIGNEE(S) | MADE IN SPACE, INC. (Moffett Field, California) |
| INVENTOR(S) | Michael Snyder (Mountain View, California); Jason Dunn (Mountain View, California); Michael Chen (Mountain View, California); Aaron Kemmer (Mountain View, California); Noah Paul-Gin (San Francisco, California); Matthew Napoli (Sunnyvale, California); Eddie Gonzalez (San Francisco, California); Michael Pless (Lodi, California) |
| ABSTRACT | Additive manufacturing devices operable in various external force environments are disclosed. In an aspect, an additive manufacturing device operable in microgravity is disclosed. In other aspects, devices which are operable in high-vibration environments or varying external force environments are disclosed. Additive manufacturing devices herein may produce parts from metal, polymer, or other feedstocks. |
| FILED | Tuesday, July 15, 2014 |
| APPL NO | 14/331729 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/25 (20170801) B29C 64/118 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/259 (20170801) B29C 64/321 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078897 | Reeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Jonathan Reeh (College Station, Texas); Jeffrey S. Parkey (College Station, Texas); Alan Cisar (Cypress, Texas); Duncan Hitchens (Allen, Texas) |
| ABSTRACT | The present invention includes an electrochemical actuator pump and method of making the same, comprising a membrane electrode assembly comprising an ion exchange membrane, a first and a second catalyzed porous electrode in contact with opposing sides of the ion exchange membrane; a first gas chamber in fluid communication with the first electrode, and a second gas chamber in fluid communication with the second electrode; and a controller for controllably reversing the polarity of a voltage source electrically coupled to the first and second electrodes, wherein the controller causes a first polarity at the first electrode to function as an anode and the second electrode to function as a cathode, wherein the first polarity simultaneously decreases the hydrogen gas pressure in the first hydrogen gas chamber and increases the hydrogen gas pressure in the second hydrogen gas chamber, with additional embodiment using MOF or Ni—H batteries. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015958 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 19/24 (20130101) F04B 43/06 (20130101) F04B 43/0054 (20130101) Original (OR) Class F04B 45/02 (20130101) F04B 45/024 (20130101) F04B 45/0336 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078984 | Gant et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederick Scott Gant (Huntsville, Alabama); Robert E. Berry (Madison, Alabama); W. Neill Myers (Huntsville, Alabama); Jeffrey Lee Lindner (Madison, Alabama); John S. Townsend (Union Grove, Alabama) |
| ABSTRACT | A damping system includes a spool about which a tension line is wound. The line's first end is coupled to a first structure subject to forces causing unwanted movement thereof. A damper is coupled to a second structure not subject to the unwanted movement of the first structure. The damper is coupled to the spool for engagement with the spool to slow a rotational speed thereof when the spool rotates in a first direction. The damper is disengaged from the spool when the spool rotates in a second direction in opposition to the first direction. A device, coupled to the line's second end and to the second structure, applies a tension force to the line's second end. The tension force is exceeded when the first structure moves to place the line in tension, and is not exceeded when the first structure moves to place the line in compression. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/063319 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 15/022 (20130101) Original (OR) Class F16F 15/1201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11077421 | Srinivas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Steven Dietz (Englewood, Colorado) |
| ABSTRACT | The present invention relates to a carbon sorbent the can selectively remove platinum-group metals and other heavy metals such as tin without co-removing organic synthesis products including pharmaceutical intermediates and finished Active Pharmaceutical Ingredients (APIs). The carbon sorbents of the present invention are made from low-cost, high purity starting materials and the resulting carbon sorbents are also very pure. The carbon sorbents possess a combination of certain nitrogen and phosphorous groups combined with mesoporosity (2 to 50 nm diameter pores) that proves the high metal adsorption. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 16/128293 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 15/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) Original (OR) Class B01J 20/305 (20130101) B01J 20/3078 (20130101) B01J 20/28057 (20130101) B01J 20/28061 (20130101) B01J 20/28064 (20130101) B01J 20/28066 (20130101) B01J 20/28069 (20130101) B01J 20/28071 (20130101) B01J 20/28083 (20130101) B01J 2220/4825 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/30 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) C01P 2006/14 (20130101) C01P 2006/16 (20130101) C01P 2006/80 (20130101) Acyclic or Carbocyclic Compounds C07C 67/34 (20130101) C07C 67/56 (20130101) C07C 201/12 (20130101) C07C 201/16 (20130101) Heterocyclic Compounds C07D 209/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11081722 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Navitas Systems, LLC (Woodridge, Illinois) |
| ASSIGNEE(S) | Navitas Systems, LLC (Lisle, Illinois) |
| INVENTOR(S) | Pu Zhang (Ann Arbor, Michigan); Michael Wixom (Ann Arbor, Michigan); Qingliu Wu (Ann Arbor, Michigan) |
| ABSTRACT | Provided are electrode active materials that include a metal oxide or oxynitride with a porous structure that when loaded with sulfur serve as electrochemically superior cathode active materials. The metal nitride or metal oxynitride structures are optionally used on their own, are coated with another material, or itself coats another porous structure such as a porous carbon structure that allows for excellent retention of both sulfur and polysulfides, are conductive themselves, and show long term stability and excellent cycle life. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/756384 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/808 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 11082412 | Leavy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wickr Inc. (San Francisco, California) |
| ASSIGNEE(S) | Wickr Inc. (Pleasanton, California) |
| INVENTOR(S) | Thomas Michael Leavy (River Edge, New Jersey); Christopher Howell (Freehold, New Jersey); Joël Alwen (Vienna, Austria) |
| ABSTRACT | A method, system, and non-transitory computer readable medium are described for providing a sender a plurality of ephemeral keys such that a sender and receiver can exchange encrypted communications. Accordingly, a sender may retrieve information, such as a public key and a key identifier, for the first receiver from a local storage. The retrieved information may be used to generate a key-encrypting key that is used to generate a random communication encryption key. The random communication encryption key is used to encrypt a communication, while the key-encrypting key encrypts the random communication key. The encrypted communication and the encrypted random communication key are transmitted to the first receiver. |
| FILED | Wednesday, July 12, 2017 |
| APPL NO | 15/647569 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) G06F 21/606 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 9/0822 (20130101) H04L 9/0825 (20130101) H04L 9/0841 (20130101) H04L 9/0869 (20130101) H04L 9/0894 (20130101) H04L 63/062 (20130101) H04L 63/068 (20130101) H04L 63/0442 (20130101) Original (OR) Class H04L 2209/08 (20130101) H04L 2209/601 (20130101) H04L 2463/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11077158 | Lei |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Xingen Lei (Ithaca, New York) |
| ABSTRACT | The present invention relates to omega-3 fatty acid enrichment, and n-6 to n-3 fatty acid ratio improvement, of poultry products using animal feed supplemented with defatted microalgae, and treatment methods involving such poultry products. One aspect of the present invention relates to a method of producing poultry eggs with elevated amounts of n-3 fatty acids. This method involves feeding poultry an amount of defatted microalgae under conditions effective for the poultry to produce an egg comprising about 300 mg to about 550 mg of n-3 fatty acids. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 15/326837 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fodder A23K 10/16 (20160501) A23K 50/75 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 15/20 (20160801) A23L 33/30 (20160801) A23L 33/115 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/57 (20130101) A61K 36/02 (20130101) A61K 36/05 (20130101) Original (OR) Class A61K 36/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11078432 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| INVENTOR(S) | Bin Yang (Pullman, Washington); Hongliang Wang (Pullman, Washington) |
| ABSTRACT | Bimetallic catalysts for the hydrodeoxygenation (HDO) conversion of lignin into useful hydrocarbons are provided. The catalysts are bifunctional bimetallic ruthenium catalysts Ru-M/X+Y comprising a metal M such as iron (Fe), nickel (Ni), copper (Cu) or zinc (Zn), zeolite Y and cation X+ (e.g. H+) associated with zeolite Y. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990077 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/088 (20130101) B01J 29/126 (20130101) B01J 29/146 (20130101) B01J 35/1023 (20130101) B01J 35/1038 (20130101) B01J 35/1061 (20130101) B01J 37/0201 (20130101) B01J 2229/186 (20130101) Acyclic or Carbocyclic Compounds C07C 1/22 (20130101) C07C 1/22 (20130101) C07C 1/22 (20130101) C07C 13/18 (20130101) C07C 13/18 (20130101) C07C 13/28 (20130101) C07C 13/28 (20130101) C07C 2523/06 (20130101) C07C 2523/46 (20130101) C07C 2523/72 (20130101) C07C 2523/78 (20130101) C07C 2523/89 (20130101) C07C 2523/745 (20130101) C07C 2523/755 (20130101) C07C 2529/12 (20130101) C07C 2529/14 (20130101) C07C 2601/14 (20170501) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/44 (20130101) C10G 3/45 (20130101) C10G 3/49 (20130101) C10G 3/50 (20130101) C10G 45/06 (20130101) C10G 45/12 (20130101) Original (OR) Class C10G 2300/202 (20130101) C10G 2300/1014 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/10 (20130101) C10L 1/1691 (20130101) C10L 2200/0469 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11077178 | Perera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Liyanage Parakrama Perera (Bethesda, Maryland); Thomas Alexander Waldmann (Bethesda, Maryland); Kevin Charles Conlon (Bethesda, Maryland); Pin-Yu Perera (Washington, District of Columbia) |
| ABSTRACT | A chimeric antigen receptor is disclosed that includes: (a) an scFv comprising a light chain variable domain (VL) and a heavy chain variable domain (VH), wherein the scFv specifically binds to CCR4; (b) a hinge and transmembrane domain from CD8; (c) an intracellular 4-1BB signaling domain; and (d) an intracellular CD3 zeta signaling domain, wherein (a)-(d) are in N to C terminal order. Uses of the chimeric antigen receptor, such as for treating a malignancy, are also disclosed. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 16/334724 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) A61K 31/7076 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2866 (20130101) C07K 2317/24 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11078093 | Cwiertny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | David Cwiertny (Iowa City, Iowa); Nosang Myung (Riverside, California); Katherine T. Peter (Iowa City, Iowa); Gene Francis Parkin (Iowa City, Iowa) |
| ABSTRACT | A method is disclosed for synthesizing nanofilters for water treatment. The method includes: dispersing an active binding agent in an organic solvent solution to create a suspension of the active binding agent and the solution of the solvent; dissolving an organic polymer resin and an anionic surfactant in the suspension of the active binding agent and the solvent solution to create a sol gel; and electrospinning the sol gel to form electrospun nanofiber composites with embedded, surface-active nanoparticles. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023808 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 39/1623 (20130101) B01D 2239/10 (20130101) B01D 2239/025 (20130101) B01D 2239/0208 (20130101) B01D 2239/0258 (20130101) B01D 2239/0407 (20130101) B01D 2239/0618 (20130101) B01D 2239/0631 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0229 (20130101) B01J 20/261 (20130101) B01J 20/28007 (20130101) B01J 20/28023 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/003 (20130101) C02F 1/50 (20130101) C02F 1/281 (20130101) C02F 1/288 (20130101) Original (OR) Class C02F 1/505 (20130101) C02F 2101/20 (20130101) C02F 2101/22 (20130101) C02F 2101/103 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 1/103 (20130101) D01F 6/18 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) D04H 3/007 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2505/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
MITRE Corporation (MITRE)
| US 11080399 | Keppler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | David Keppler (Herndon, Virginia); Ivan Lozano (Arlington, Virginia); Joseph Portner (Hampton, Virginia); Andrew Pyles (Williamsburg, Virginia); Christina L. Johns (Arlington, Virginia); David Bryson (Montgomery, Alabama) |
| ABSTRACT | A system and method for implementing a software emulation environment is provided. In one example, a mobile application can interface with an emulation environment that can be used to test whether the mobile application includes malware that can compromise the security and integrity of an enterprise's computing infrastructure. When the mobile application issues a call for data, a device mimic module can intercept the call and determine if the call includes a call for one or more checkable artifacts that can reveal the existence of the emulation environment. If such a call for data occurs, the device mimic module can provide one or more spoofed checkable artifacts that have been recorded from a real-world mobile device. In this way, the existence of the emulation environment can be concealed so as to allow for a more thorough analysis of a mobile application for potential hidden malware. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/720811 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) Original (OR) Class G06F 21/577 (20130101) G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11081609 | Boca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Andreea Boca (Sherman Oaks, California); Daniel C. Law (Arcadia, California); Joseph Charles Boisvert (Thousand Oaks, California); Nasser H. Karam (La Canada, California) |
| ABSTRACT | A semiconductor structure including a bonding layer connecting a first semiconductor wafer layer to a second semiconductor wafer layer, the bonding layer including an electrically conductive carbonaceous component and a binder component. |
| FILED | Monday, February 23, 2015 |
| APPL NO | 14/628923 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/2007 (20130101) H01L 31/18 (20130101) H01L 31/043 (20141201) H01L 31/0687 (20130101) Original (OR) Class H01L 31/0693 (20130101) H01L 31/0725 (20130101) H01L 31/1844 (20130101) H01L 31/1892 (20130101) H01L 31/1896 (20130101) H01L 31/06875 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11082347 | Dearth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nvidia Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Nvidia Corporation (Santa Clara, California) |
| INVENTOR(S) | Glenn Dearth (Santa Clara, California); Nan Jiang (Santa Clara, California); John Wortman (Santa Clara, California); Alex Ishii (Santa Clara, California); Mark Hummel (Santa Clara, California); Rich Reeves (Santa Clara, California) |
| ABSTRACT | Multiple processors are often used in computing systems to solve very large, complex problems, such as those encountered in artificial intelligence. Such processors typically exchange data among each other via an interconnect fabric (such as, e.g., a group of network connections and switches) in solving such complex problems. The amount of data injected into the interconnect fabric by the processors can at times overwhelm the interconnect fabric preventing some of the processors from communicating with each other. To address this problem, techniques are disclosed to enable, for example, processors that are connected to an interconnect fabric to coordinate and control the amount of data injected so that the interconnect fabric does not get overwhelmed. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277349 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/16 (20130101) H04L 43/0888 (20130101) H04L 47/18 (20130101) H04L 47/39 (20130101) H04L 47/127 (20130101) Original (OR) Class H04L 47/263 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11077541 | Alabi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Oluwaseun B. Alabi (South Windsor, Connecticut) |
| ABSTRACT | A tool system to install an interference fit component within a bore of a component, includes a guide bushing that at least partially fits within a bore of a component. A drive screw is of a length to extend through the guide bushing and the bore. A threaded insert is receivable at least partially within the bore, the threaded insert receivable at least partially within the interference fit component. |
| FILED | Wednesday, July 03, 2019 |
| APPL NO | 16/502432 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 27/023 (20130101) Original (OR) Class B25B 27/026 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) F05D 2230/64 (20130101) F05D 2260/37 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11078842 | Thomas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael R. Thomas (Bloomfield, Connecticut) |
| ABSTRACT | A cooling system for a gas turbine engine may comprise a heat exchanger configured to receive a cooling airflow. The heat exchanger may receive the cooling flow at a cooling flow input of the heat exchanger and output the cooling airflow at an exhaust output of the heat exchanger. An exhaust distribution manifold may be fluidly coupled to the exhaust output of the heat exchanger. The exhaust distribution manifold may define a plurality of openings. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 16/365235 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) F02C 7/141 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 03, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page