FedInvent™ Patents

Patent Details for Tuesday, September 07, 2021 

This page was updated on Wednesday, September 08, 2021 at 04:00 AM GMT

Department of Health and Human Services (HHS) 

US 11109758 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ABSTRACT Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
FILED Thursday, March 08, 2018
APPL NO 15/915180
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0064 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0073 (20130101)
A61B 5/0075 (20130101)
A61B 5/0088 (20130101)
A61B 5/444 (20130101)
A61B 5/445 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0242 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 3/457 (20130101)
G01J 3/2889 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/2476 (20130101)
G02B 26/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109759 Iftimia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Physical Sciences, Inc. (Andover, Massachusetts)
ASSIGNEE(S) Physical Sciences, Inc. (Andover, Massachusetts)
INVENTOR(S) Nicusor V. Iftimia (Chelmsford, Massachusetts);  Whanwook Chang (Fort Lee, New Jersey)
ABSTRACT A handheld optical coherence tomography imaging and tissue sampling system and method of imaging and sampling a tissue is disclosed. The method includes inserting a catheter probe into a biopsy needle. The biopsy needle can be attached to a hand-held scanning and sampling device. The biopsy needle is maneuvered to an investigation site. A three-dimensional image of the tissue at the investigation site is captured with the catheter probe.
FILED Wednesday, February 28, 2018
APPL NO 15/907557
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/065 (20130101)
A61B 5/0066 (20130101) Original (OR) Class
A61B 5/0071 (20130101)
A61B 5/0075 (20130101)
A61B 5/0084 (20130101)
A61B 5/742 (20130101)
A61B 5/6848 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109763 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S) Ji-xin Cheng (West Lafayette, Indiana);  Pu Wang (West Lafayette, Indiana);  Yingchun Cao (West Lafayette, Indiana);  Jie Hui (West Lafayette, Indiana)
ABSTRACT A photoacoustic catheter includes an elongated catheter body and a housing positioned near a distal end of the elongated catheter body. A length of multimode fiber extends through the elongated catheter body and has a distal end that is beveled at about 45° relative to a longitudinal axis of the multimode fiber and is positioned in the housing. An ultrasonic transducer, electrically connected to an electrical wire extending along the elongated catheter body, is positioned within the housing. A mirror element is also positioned within the housing and includes a mirror surface beveled at about 45° relative to the longitudinal axis of the multimode fiber. The catheter is operable to deliver an optical wave through the multimode fiber and to deliver an ultrasonic wave collinearly from the housing and out of an aperture of the housing to obtain optical data and ultrasonic data within a mammalian luminal organ.
FILED Monday, February 13, 2017
APPL NO 15/998889
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)
A61B 5/0095 (20130101) Original (OR) Class
A61B 5/02007 (20130101)
A61B 8/12 (20130101)
A61B 8/445 (20130101)
A61B 2560/0233 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0067 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109768 Mehrotra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Sanjay Mehrotra (Winnetka, Illinois);  Ilya Mikhelson (Wilmette, Illinois);  Alan V. Sahakian (Northbrook, Illinois)
ABSTRACT Representative methods, apparatus and systems are disclosed for blood pressure and other vital sign monitoring using arterial applanation tonometry, including ambulatory blood pressure and other vital sign monitoring. A representative system comprises a wearable apparatus. The various embodiments measure blood pressure and other vital sign monitoring using a plurality of pressure sensors of a pressure sensor array, with one or more of the pressure sensors 140 applanating an artery, such as a radial artery. In a first embodiment, a pressure sensor signal is utilized which has the highest cross-coherence with the signals of its nearest pressure sensor neighbors of the pressure sensor array. In a second embodiment, Kalman filtering is utilized for the pressure sensor signals from the pressure sensor array.
FILED Tuesday, June 20, 2017
APPL NO 15/627911
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02 (20130101)
A61B 5/02108 (20130101) Original (OR) Class
A61B 5/6824 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109782 Esenaliev et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Rinat O. Esenaliev (League City, Texas);  Donald S. Prough (Galveston, Texas);  Yuriy Petrov (Galveston, Texas);  Irene Y. Petrov (Galveston, Texas);  C. Joan Richardson (Galveston, Texas)
ABSTRACT Disclosed herein are systems and methods for monitoring one or more of cerebral oxygenation and total hemoglobin concentration that can be used to perform accurate, noninvasive measurement of cerebral venous blood oxygen saturation (oxygenation) in neonatal patients. A neonatal cerebral oxygenation detection apparatus comprises a wearable support having a light emitter and an acoustic sensor coupled thereto. The wearable support can be secured onto a head of an infant, and the light emitter can be configured to emit a light toward a superior sagittal sinus of the infant's head. The acoustic sensor can be configured to detect acoustic pressure generated by blood in the superior sagittal sinus when the superior sagittal sinus blood absorbs the light. Cerebral oxygenation and/or total hemoglobin concentration can be determined based on the acoustic pressure detected by the acoustic detector.
FILED Wednesday, January 16, 2019
APPL NO 16/249180
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0095 (20130101)
A61B 5/6803 (20130101)
A61B 5/14542 (20130101)
A61B 5/14546 (20130101)
A61B 5/14552 (20130101) Original (OR) Class
A61B 5/14553 (20130101)
A61B 2503/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110067 Sharp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas);  Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas);  Southwest Research Institute (San Antonio, Texas)
INVENTOR(S) Zelton Dave Sharp (San Antonio, Texas);  John R. Strong (San Antonio, Texas);  Veronica Galvan (San Antonio, Texas);  Salvatore Oddo (San Antonio, Texas);  Herbert G. Wheeler (Boerne, Texas)
ABSTRACT Disclosed are microcapsules that include an inhibitor of the mammalian target of rapamycin (mTOR) within the microcapsules, and pharmaceutical compositions and kits that include the microcapsules. Also disclosed are methods for treating or preventing an age-related disease, condition, or disorder in a subject that involve administering to a subject a pharmaceutically effective amount of microcapsules that includes an inhibitor of mTOR within the microcapsules.
FILED Tuesday, August 27, 2019
APPL NO 16/552380
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1635 (20130101)
A61K 9/5026 (20130101)
A61K 31/00 (20130101) Original (OR) Class
A61K 31/436 (20130101)
A61K 31/436 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110070 Brachman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Child Health and Human Development (NICHD)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Rebecca Anne Brachman (Westfield, New Jersey);  Christine Ann Denny (New York, New York);  René Hen (Tenafly, New Jersey)
ABSTRACT Methods for prophylactically treating a stress-induced affective disorder or stress-induced psychopathology in a subject are provided. Also provided are methods for inducing and/or enhancing stress resilience in a subject. In certain embodiments, an effective amount, of an antagonist of the glutamate N-methyl-D-aspartate (NMDA) receptor, such as ketamine, or a pharmaceutically acceptable salt or derivative thereof, is administered to a subject prior to a stressor.
FILED Thursday, November 17, 2016
APPL NO 15/776880
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/0053 (20130101)
A61K 31/42 (20130101)
A61K 31/42 (20130101)
A61K 31/53 (20130101)
A61K 31/53 (20130101)
A61K 31/135 (20130101)
A61K 31/135 (20130101)
A61K 31/138 (20130101) Original (OR) Class
A61K 31/138 (20130101)
A61K 31/198 (20130101)
A61K 31/198 (20130101)
A61K 31/401 (20130101)
A61K 31/401 (20130101)
A61K 31/428 (20130101)
A61K 31/428 (20130101)
A61K 31/445 (20130101)
A61K 31/445 (20130101)
A61K 31/453 (20130101)
A61K 31/453 (20130101)
A61K 31/513 (20130101)
A61K 31/513 (20130101)
A61K 31/517 (20130101)
A61K 31/517 (20130101)
A61K 31/4245 (20130101)
A61K 31/4245 (20130101)
A61K 31/4525 (20130101)
A61K 31/4525 (20130101)
A61K 33/00 (20130101)
A61K 33/00 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/22 (20180101)
A61P 25/24 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110076 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Alagramam N. Kumar (Cleveland, Ohio);  Suhasini Gopal Ramanujam (Cleveland, Ohio)
ABSTRACT A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor.
FILED Tuesday, February 18, 2020
APPL NO 16/793861
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/343 (20130101)
A61K 31/357 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/16 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110079 Riggins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Gregory Riggins (White Hall, Maryland);  Renyuan Bai (Joppa, Maryland);  Verena Staedtke (Baltimore, Maryland);  Avadhut D. Joshi (Baltimore, Maryland);  Tara Williamson (Baltimore, Maryland)
ABSTRACT Mebendazole is an antiparasitic drug with over 40 years of safe use. Recently mebendazole was repurposed for glioblastoma therapy. Three polymorphs of mebendazole exist, but the relative polymorph content for existing drugs varies, and the therapeutic anti-cancer relevance of the different polymorphs was unknown. As an oral drug mebendazole polymorph C is a superior form, and it reaches the brain and brain tumors in effective concentrations. Efficacy is further improved by combining mebendazole with a P-glycoprotein inhibitor. Mebendazole may also be used for therapy of other cancers, as well as a chemo-preventative agent.
FILED Monday, February 08, 2016
APPL NO 15/548959
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 33/10 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/50 (20130101)
A61K 9/0056 (20130101)
A61K 9/1605 (20130101)
A61K 31/192 (20130101)
A61K 31/192 (20130101)
A61K 31/473 (20130101)
A61K 31/473 (20130101)
A61K 31/4184 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110080 Reens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of Colorado, a body Corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Abigail L. Reens (Boulder, Colorado);  Amy L. Crooks (Erie, Colorado);  Corrella S. Detweiler (Boulder, Colorado)
ABSTRACT An empirical Screen for Anti-infectives using Fluorescence microscopy of IntracellulaR Enterobacteriaceae (SAFIRE) was developed. Using this methodology, a library of small molecules and identified antimicrobials that are cell permeable and non-host-toxic were screened. Inhibitors of bacterial efflux pumps were identified as being implicated in antibiotic resistance and are attractive therapeutic targets for antimicrobials.
FILED Tuesday, March 27, 2018
APPL NO 16/497315
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/65 (20130101)
A61K 31/426 (20130101) Original (OR) Class
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 38/12 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110085 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Qi Zhou (West Lafayette, Indiana);  Nivedita Shetty (West Lafayette, Indiana)
ABSTRACT The present disclosure generally relates to a combination dry powder inhaler (DPI) formulation of Ciprofloxacin and Colistin through co-spray drying, particularly to a co-sprayed colistin and Ciprofloxacin dry powder inhaler for the treatment of various bacterial infections. Methods of use and composition matters are within the scope of this disclosure.
FILED Friday, April 26, 2019
APPL NO 16/395302
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0075 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 38/12 (20130101)
A61K 47/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110089 Arnér et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Elias Set Jenö Arnér (Stockholm, Sweden);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Elias Set Jenö Arnér (Stockholm, Sweden)
INVENTOR(S) Elias Set Jenö Arnér (Stockholm, Sweden);  William Chester Stafford (Stockholm, Sweden);  Nathan Patrick Coussens (Vienna, Virginia);  Diane Karen Luci (Germantown, Maryland);  David Joseph Maloney (Point Of Rocks, Maryland);  Anton Simeonov (Bethesda, Maryland);  Ajit Jadhav (Chantilly, Virginia);  Thomas S. Dexheimer (Lansing, Michigan)
ABSTRACT There is provided compounds of formula (I) or pharmaceutically-acceptable salts thereof, wherein W, X, Y, Z, R1, R2 and R3 have meanings provided in the description, which compounds are useful in the treatment of cancers.
FILED Friday, August 05, 2016
APPL NO 15/750817
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/501 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 413/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110098 Rao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Reena Rao (Overland Park, Kansas)
ABSTRACT The present disclosure is directed, among other things, to the surprising and unexpected efficacy provided by select V2R antagonists in significantly reducing the cell proliferation levels of clear cell renal cell carcinoma. Thus, the present disclosure provides methods, uses, and medicaments that include such select V2R antagonists for utility in treating clear cell renal cell carcinoma.
FILED Wednesday, June 06, 2018
APPL NO 16/614997
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101) Original (OR) Class
A61K 31/55 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110104 Slusher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
NIH Office of the Director (NIHOD)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Icahn School of Medicine at Mount Sinai (New York, New York)
INVENTOR(S) Barbara Slusher (Kingsville, Maryland);  David Volsky (Scarsdale, New York);  Mike Nedelcovych (Richmond, Virginia);  Kristen Hollinger (Parkton, Maryland);  Atsushi Kamiya (Pikesville, Maryland)
ABSTRACT The disclosure provides compounds having formula (I):
and the pharmaceutically acceptable salts thereof, wherein R1, R2, R2′, and X are as defined as set forth in the specification, for use in treating cognitive deficits and/or psychiatric disorders, such as those associated with neurological or neurodegenerative disorders, psychiatric or mood disorders, and HIV-associated neurocognitive disorders (HAND). Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON).
FILED Wednesday, January 31, 2018
APPL NO 15/884974
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/42 (20130101)
A61K 31/198 (20130101)
A61K 31/223 (20130101)
A61K 31/655 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110107 Lin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Hening Lin (Ithaca, New York)
ABSTRACT This disclosure demonstrates that inhibition of Sirt5 can suppress malignant transformation of cells. Therefore, methods of treating cancer based on inhibition of Sirt5 are disclosed.
FILED Friday, May 17, 2019
APPL NO 16/414912
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/198 (20130101)
A61K 31/702 (20130101)
A61K 31/713 (20130101)
A61K 31/7016 (20130101) Original (OR) Class
A61K 31/7088 (20130101)
A61K 38/00 (20130101)
A61K 38/02 (20130101)
A61K 38/03 (20130101)
A61K 38/1709 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
C12N 2310/14 (20130101)

Enzymes
C12Y 305/01098 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110111 Hirano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Michio Hirano (New York, New York);  Caterina Garone (Cambridge, United Kingdom);  Ramon Marti (Barcelona, Spain)
ABSTRACT The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxynucleoside, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine (dT) or deoxycytidine (dC), or mixtures thereof. This administration of deoxynucleosides is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome.
FILED Thursday, September 26, 2019
APPL NO 16/583852
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/513 (20130101)
A61K 31/513 (20130101)
A61K 31/708 (20130101)
A61K 31/708 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 31/7072 (20130101) Original (OR) Class
A61K 31/7072 (20130101)
A61K 31/7076 (20130101)
A61K 31/7076 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)
A61P 43/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110132 McGwire
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Bradford McGwire (Columbus, Ohio)
ABSTRACT Disclosed herein is an avirulent live vaccine that involves a recombinant protozoan from the order Trypanosomatida having a knocked out or silenced cyclophilin gene, wherein the cyclophilin gene comprises T. cruzi cyclophilin 19 (TcCyp19) gene, or an orthologue thereof. Also disclosed is a method or inducing a protective immune response in a subject that involves administering to the subject a vaccine disclosed herein. Also disclosed is a method of treating or preventing Chagas disease, African trypanosomiasis, and/or leishmaniasis in a subject that involves administering to the subject a vaccine disclosed herein.
FILED Wednesday, November 06, 2019
APPL NO 16/675842
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/68 (20130101) Original (OR) Class
A61K 39/005 (20130101)
A61K 2039/522 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110148 Kaplan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Rina Sears (Pine Meadow, Connecticut);  Gordana Vunjak-Novakovic (New York, New York);  Lorenz Meinel (Niestetal, Germany)
ABSTRACT The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
FILED Thursday, May 17, 2018
APPL NO 15/981981
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1825 (20130101) Original (OR) Class
A61K 38/1841 (20130101)
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/56 (20130101)
A61L 27/227 (20130101)
A61L 27/3604 (20130101)
A61L 27/3847 (20130101)
A61L 27/3852 (20130101)
A61L 27/3895 (20130101)

Compositions of Macromolecular Compounds
C08L 89/00 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/00 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 4/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/29 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110150 Felber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) NOVARTIS AG (Basel, Switzerland);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) NOVARTIS AG (Basel, Switzerland);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Barbara K. Felber (Rockville, Maryland);  Sergio Finkielsztein (Newton, Massachusetts);  George N. Pavlakis (Bethesda, Maryland);  John V. Vournakis (Charleston, South Carolina)
ABSTRACT The present invention relates to agents that modulate interleukin-15 (“IL-15”) signal transduction or function (“Therapeutic Agents”) and the use ol” those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-β-1-♦4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.
FILED Monday, March 04, 2019
APPL NO 16/291561
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/13 (20130101)
A61K 38/1793 (20130101)
A61K 38/2086 (20130101) Original (OR) Class
A61K 39/0011 (20130101)
A61K 39/00114 (20180801)
A61K 47/36 (20130101)
A61K 2039/5152 (20130101)
A61K 2039/5156 (20130101)
A61K 2039/55527 (20130101)

Peptides
C07K 16/244 (20130101)
C07K 16/2866 (20130101)
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0686 (20130101)
C12N 15/85 (20130101)
C12N 2500/90 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110152 Ledford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Julie Ledford (Tucson, Arizona);  Monica Kraft (Tucson, Arizona)
ABSTRACT Provided herein are compositions and methods for treating and preventing lung disease. In particular, provided herein are SP-A peptides and uses thereof in the treatment and prevention of lung disease (e.g., asthma or COPD).
FILED Tuesday, April 11, 2017
APPL NO 16/093063
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/008 (20130101)
A61K 38/395 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110164 August et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Thomas August (Baltimore, Maryland);  Ernesto Marques, Jr. (Baltimore, Maryland)
ABSTRACT The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient.
FILED Thursday, May 10, 2018
APPL NO 15/976453
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/70596 (20130101)
C07K 2319/00 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/62 (20130101)
C12N 15/86 (20130101)
C12N 2740/16234 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110171 Mor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Adam Mor (Cresskill, New Jersey);  Ben Neel (New York, New York)
ABSTRACT Provided are compositions and methods for identifying individuals with cancer who will benefit from PD-1 inhibitor therapy. The method comprises determining levels of signaling lymphocyte activation molecule-associated protein (SAP) in an individual and based on the SAP levels, determining if the individual is suitable for PD-1 inhibitor therapy. Also provided is a method of treatment of X-linked lymphoproliferative disease comprising administering to an individual PD-1 inhibitory therapy, with or without SHP2 inhibitors.
FILED Friday, December 21, 2018
APPL NO 16/956451
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/343 (20130101)
A61K 31/404 (20130101)
A61K 31/497 (20130101)
A61K 31/4412 (20130101)
A61K 31/4535 (20130101)
A61K 31/4704 (20130101)
A61K 38/465 (20130101)
A61K 39/3955 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2803 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
G01N 33/57484 (20130101)
G01N 2560/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110175 Kohane et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel S. Kohane (Newton, Massachusetts);  Rong Yang (Cambridge, Massachusetts);  Lily Yun Lin (Austin, Texas)
ABSTRACT The present invention provides compositions and methods for delivery of therapeutic agents across an barrier. The compositions include a therapeutic agent (e.g., antimicrobial agent, antibiotic, or anesthetic agent), a permeation enhancer which increases the flux of the therapeutic agent across the barrier, and a matrix forming agent. The matrix forming agent forms a gel at a suitable gelation temperature and rheological properties for use in drug delivery, and in some cases, the gelation temperature and rheological properties are not significantly changed from those of the composition without the permeation enhancer. The invention also provides a matrix forming agent and compositions thereof. Such compositions are particularly useful in the treatment of otitis media. Methods of treatment, methods of delivery, and kits for the compositions described herein are also provided.
FILED Friday, August 05, 2016
APPL NO 15/749951
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0046 (20130101)
A61K 31/407 (20130101)
A61K 31/407 (20130101)
A61K 31/424 (20130101)
A61K 31/424 (20130101)
A61K 31/431 (20130101)
A61K 31/431 (20130101)
A61K 31/445 (20130101)
A61K 31/445 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/573 (20130101)
A61K 31/573 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 31/5383 (20130101)
A61K 31/5383 (20130101)
A61K 38/12 (20130101)
A61K 45/06 (20130101)
A61K 47/06 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101)
A61K 47/20 (20130101)
A61K 47/22 (20130101)
A61K 47/26 (20130101)
A61K 47/34 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/16 (20180101)
A61P 31/04 (20180101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/3355 (20130101)
C08G 79/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110176 Wen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Xin Wen (Alhambra, California)
ASSIGNEE(S) The Board of Trustees of the California State University (Long Beach, California)
INVENTOR(S) Xin Wen (Alhambra, California)
ABSTRACT Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of −20-60° C.).
FILED Wednesday, November 22, 2017
APPL NO 15/821671
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0221 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/28 (20130101)
A61K 47/42 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/04 (20130101)
C12N 9/96 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110181 de los Pinos et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Aura Biosciences, Inc. (Cambridge, Massachusetts);  The United States of America, as represented by the Secretary, Department of Health and Human Serv. (Bethesda, Maryland)
ASSIGNEE(S) Aura Biosciences, Inc. (Cambridge, Massachusetts);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Elisabet de los Pinos (Brookline, Massachusetts);  John Todd Schiller (Kensington, Maryland);  Rhonda C. Kines (Washington, District of Columbia);  John MacDougall (Hingham, Massachusetts)
ABSTRACT The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules.
FILED Friday, January 31, 2020
APPL NO 16/778361
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 41/0057 (20130101)
A61K 41/0071 (20130101)
A61K 47/64 (20170801)
A61K 47/6901 (20170801) Original (OR) Class
A61K 2039/545 (20130101)
A61K 2039/585 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)

Peptides
C07K 1/13 (20130101)
C07K 14/025 (20130101)
C07K 16/32 (20130101)
C07K 16/084 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/20023 (20130101)
C12N 2710/20033 (20130101)
C12N 2710/20034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110182 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio);  Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Xiaoting Zhang (Cincinnati, Ohio);  Peixuan Guo (Cincinnati, Ohio)
ABSTRACT RNA nanoparticles functionalized with a HER2-targeting RNA aptamer and at least one MED1 siRNA for targeted delivery of MED1 siRNA to human cancer cells via human epidermal growth factor receptor 2 (HER2) receptors, pharmaceutical compositions of the inventive RNA nanoparticles, and methods for treating breast, HER2-implicated cancers, and in particular therapeutic-resistant cancer such as tamoxifen-resistant breast cancer, by administering pharmaceutical compositions of the inventive RNA nanoparticles.
FILED Friday, December 08, 2017
APPL NO 16/467690
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/566 (20130101)
A61K 31/4196 (20130101)
A61K 47/6929 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/115 (20130101)
C12N 2310/14 (20130101)
C12N 2310/16 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110197 Xia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia);  Washington University (St. Louis, Missouri)
INVENTOR(S) Younan Xia (Atlanta, Georgia);  Jianhua Li (Atlanta, Georgia);  Stavros Thomopoulos (New York, New York);  Stephen Linderman (St. Louis, Missouri);  Chunlei Zhu (Atlanta, Georgia)
ABSTRACT Disclosed herein are surgical suture materials that facilitate the sustained delivery of releasable components. The suture materials are processed by the disclosed methods to create a layer of pores extending inward from the outer surface of the suture. Particularly, the surgical suture materials are swollen in a calcium-ion containing solution, then freeze-dried to create pores which can be filled with a releasable component for ultimate delivery to the tissue. In one particular embodiment, the suture has an outer sheath that defines a lumen. Elongated filaments extend through the lumen. This suture embodiment is processed by the disclosed methods to yield a surgical suture material with a porous outer sheath. The pores enable efficient loading of a releasable component into the lumen, facilitating sustained delivery of the releasable component from the suture. The suture maintains its mechanical integrity despite the introduction of pores due to coordination bonds formed between the calcium ions of the swelling solution and carbonyl oxygen atoms of the polymer chains of the surgical suture material.
FILED Friday, February 24, 2017
APPL NO 16/078058
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/06166 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 17/04 (20130101)
A61L 17/005 (20130101)
A61L 17/10 (20130101)
A61L 17/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110207 Sakamoto et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Jeffrey S. Sakamoto (Ann Arbor, Michigan);  Dena Shahriari (Woodland Hills, California);  Mark H. Tuszynski (La Jolla, California);  Wendy Campana (La Jolla, California);  Yacov Koffler (San Diego, California)
ABSTRACT Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.
FILED Tuesday, August 20, 2019
APPL NO 16/545855
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101) Original (OR) Class
A61L 27/58 (20130101)
A61L 2300/252 (20130101)
A61L 2300/412 (20130101)
A61L 2430/32 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
C08L 89/00 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110289 Thyagarajan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Krishnan Thyagarajan (Mountain View, California);  George Daniel (Palo Alto, California);  Bernard D. Casse (Saratoga, California)
ABSTRACT An implantable magnetic neurostimulation probe includes at least one electrical conductor disposed on a substrate and arranged in at least one planar loop. At least one planar magnetic core comprising a magnetic material is disposed on the substrate and within the planar loop. A biocompatible coating is disposed over the substrate, electrically conductive trace, and magnetic core.
FILED Thursday, March 15, 2018
APPL NO 15/922693
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/24 (20210101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/40 (20130101)
A61N 1/37211 (20130101)
A61N 2/02 (20130101) Original (OR) Class
A61N 2/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110292 Rucker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Frances Joan Rucker (Boston, Massachusetts);  Hannah Yoon (Boston, Massachusetts);  Christopher Patrick Taylor (Quincy, Massachusetts)
ASSIGNEE(S) New England College of Optometry (Boston, Massachusetts)
INVENTOR(S) Frances Joan Rucker (Boston, Massachusetts);  Hannah Yoon (Boston, Massachusetts);  Christopher Patrick Taylor (Quincy, Massachusetts)
ABSTRACT A myopia-inhibiting treatment device produces a therapeutic light that includes components of different wavelengths in a ratio of luminosities that creates a predetermined L-cone to S-cone excitation profile that slows ocular growth, thereby mitigating development of myopia. The components comprise blue light, green light, and red light. Therapeutic light may cause an L-cone to S-cone excitation ratio in a range between 1.38 and 0.05. In some implementations the therapeutic light causes a L-cone to S-cone excitation ratio of 0.74. In some implementations the luminosity of the combined light components is greater than 700 lux.
FILED Thursday, March 14, 2019
APPL NO 16/353107
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0613 (20130101) Original (OR) Class
A61N 5/0622 (20130101)
A61N 2005/0628 (20130101)
A61N 2005/0642 (20130101)
A61N 2005/0648 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0652 (20130101)
A61N 2005/0663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110296 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) PULSETHERA CORPORATION (Chestnut Hill, Massachusetts)
ASSIGNEE(S) PULSETHERA, INC. (Chestnut Hill, Morocco)
INVENTOR(S) Pu-Ting Dong (Boston, Massachusetts);  Jie Hui (Boston, Massachusetts);  Ji-Xin Cheng (Newton, Massachusetts);  Yifan Zhu (Allston, Massachusetts)
ABSTRACT Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.
FILED Friday, August 28, 2020
APPL NO 17/005807
ART UNIT 1799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/40 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/10 (20130101)
A61L 2/208 (20130101)
A61L 2101/02 (20200801)
A61L 2202/26 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101) Original (OR) Class
A61N 5/0616 (20130101)
A61N 5/0624 (20130101)
A61N 2005/0635 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110459 Chatterjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) fannin partners llc (Houston, Texas)
ASSIGNEE(S) Fannin Partners LLC (Houston, Texas)
INVENTOR(S) Dev Chatterjee (Saint Louis, Missouri);  Leo Linbeck, III (Houston, Texas);  Michael John Heffernan (Katy, Texas)
ABSTRACT In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change.
FILED Tuesday, November 13, 2018
APPL NO 16/188329
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2219/00317 (20130101)
B01J 2219/00605 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/54 (20130101)
B01L 3/527 (20130101) Original (OR) Class
B01L 3/50853 (20130101)
B01L 3/502761 (20130101)
B01L 2200/12 (20130101)
B01L 2200/16 (20130101)
B01L 2200/143 (20130101)
B01L 2200/185 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0668 (20130101)
B01L 2200/0673 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/021 (20130101)
B01L 2300/069 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0887 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0677 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/78 (20130101)
G01N 33/483 (20130101)
G01N 33/5302 (20130101)
G01N 33/54333 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111222 Holinstat et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Michael Holinstat (Ann Arbor, Michigan);  Theodore R. Holman (Santa Cruz, California);  Andrew White (Ann Arbor, Michigan)
ABSTRACT 12(S)-hydroxyeicosatrienoic acid (12(S)-HETrE) compounds and compositions comprising the same are disclosed. Methods of using the compounds in the prevention and treatment of thrombosis and thrombotic disorders are also disclosed.
FILED Friday, June 23, 2017
APPL NO 16/312721
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/42 (20130101)
A61K 31/202 (20130101)
A61K 31/4192 (20130101)
A61K 31/4196 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/02 (20180101)

Acyclic or Carbocyclic Compounds
C07C 59/42 (20130101)
C07C 305/14 (20130101)

Heterocyclic Compounds
C07D 233/84 (20130101)
C07D 249/04 (20130101)
C07D 249/12 (20130101)
C07D 257/04 (20130101) Original (OR) Class

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111239 Barbosa
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GB006, INC. (San Diego, California)
ASSIGNEE(S) GB006, INC. (San Diego, California)
INVENTOR(S) Antonio J. Barbosa (Ave Maria, Florida)
ABSTRACT The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating β2 integrin-mediated diseases and conditions using the salts and crystalline forms.
FILED Tuesday, November 05, 2019
APPL NO 16/675097
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Acyclic or Carbocyclic Compounds
C07C 215/08 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111251 Lindsley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Craig W. Lindsley (Brentwood, Tennessee);  P. Jeffrey Conn (Nashville, Tennessee);  Darren W. Engers (Brentwood, Tennessee);  Katrina A. Bollinger (Murfreesboro, Tennessee);  Julie L. Engers (Brentwood, Tennessee)
ABSTRACT Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof.
FILED Thursday, February 16, 2017
APPL NO 15/998899
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111252 Gangjee
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania)
INVENTOR(S) Aleem Gangjee (Allison Park, Pennsylvania)
ABSTRACT The present invention discloses a compound of the formula: and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt or hydrate thereof.
FILED Tuesday, August 11, 2020
APPL NO 16/947651
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/343 (20130101)
A61K 31/505 (20130101)
A61K 31/4709 (20130101)

Heterocyclic Compounds
C07D 239/48 (20130101)
C07D 403/02 (20130101)
C07D 405/02 (20130101)
C07D 487/04 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111253 Huryn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Donna M. Huryn (Allentown, Pennsylvania);  Peter Wipf (Pittsburgh, Pennsylvania);  Jennifer Rubin Grandis (Pittsburgh, Pennsylvania);  Matthew G. LaPorte (Pittsburgh, Pennsylvania);  Paul A. Johnston (Sewickley, Pennsylvania);  Mark E. Schurdak (Pittsburgh, Pennsylvania);  Raffaele Colombo (Pittsburgh, Pennsylvania)
ABSTRACT Compounds that selectivity inhibit the STAT3 pathway and not the STAT1 pathway and exhibit anti-proliferative activity are disclosed. Also disclosed are methods of treatment of cancers that are characterized by overexpression of STAT3, which are safer that other therapies.
FILED Friday, April 10, 2020
APPL NO 16/846089
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 513/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111270 Cosford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California)
ASSIGNEE(S) SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California)
INVENTOR(S) Nicholas David Peter Cosford (La Jolla, California);  Mitchell Dennis Vamos (La Jolla, California)
ABSTRACT Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
FILED Friday, January 10, 2020
APPL NO 16/740240
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 487/14 (20130101)
C07D 498/04 (20130101)
C07D 498/10 (20130101)
C07D 513/04 (20130101)

Peptides
C07K 5/0806 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111275 Morrison
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) The University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Trudy Gilkerson Morrison (Northborough, Massachusetts)
ABSTRACT The present invention provides compositions and methods for using prophylactic and/or therapeutic vaccines to immunize subjects, and offspring of immunized female subjects, against respiratory syncytial virus (RSV). The invention also provides compositions and methods for producing increased yields of recombinant virus-like particles (VLPs).
FILED Thursday, September 19, 2019
APPL NO 16/575784
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/155 (20130101)
A61K 2039/55 (20130101)
A61K 2039/58 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/18123 (20130101)
C12N 2760/18143 (20130101)
C12N 2760/18522 (20130101)
C12N 2760/18534 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111278 Olson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Eric N. Olson (University Park, Texas);  Rhonda S. Bassel-Duby (Dallas, Texas);  Catherine A. Makarewich (Dallas, Texas);  Benjamin R. Nelson (Dallas, Texas)
ABSTRACT The present disclosure describes a new native peptide designated herein as Dwarf Open Reading Frame, or DWORF. This peptide enhances the apparent activity of the SERCA pump, is positively inotropic and lusitropic, and therefore is provided as a therapeutic agent for disorders characterized by cytosolic calcium overload.
FILED Wednesday, January 15, 2020
APPL NO 16/743831
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101)
A61K 45/06 (20130101)
A61K 48/0058 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111282 Spees
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The University of Vermont and State Agriculture College (Burlington, Vermont)
ASSIGNEE(S) THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (Burlington, Vermont)
INVENTOR(S) Jeffrey Spees (Burlington, Vermont)
ABSTRACT As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
FILED Thursday, February 07, 2019
APPL NO 16/270365
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/18 (20130101)
A61K 38/1833 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/475 (20130101) Original (OR) Class
C07K 14/4753 (20130101)
C07K 14/70503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111296 Thomas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Cambridge, Massachusetts)
INVENTOR(S) David K. Thomas (Boston, Massachusetts);  Todd R. Golub (Cambridge, Massachusetts)
ABSTRACT The invention provides compositions and methods for treating cardiac dysfunction, particularly cachexia-associated or RAGE-associated cardiac dysfunction, using an anti-RAGE agent. The invention also provides compositions and methods for identifying therapeutic agents useful for disrupting (slowing, reducing, reversing, or preventing). The methods comprise designing or identifying agents that bind to functional sites identified on the RAGE polypeptide, wherein binding of agents to the functional site(s) inhibit RAGE-mediated cachetogenic signaling.
FILED Tuesday, December 13, 2016
APPL NO 16/061652
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1774 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/04 (20180101)
A61P 9/10 (20180101)

Peptides
C07K 16/2803 (20130101) Original (OR) Class
C07K 2317/34 (20130101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 10/00 (20190201)
G16C 20/00 (20190201)
G16C 20/20 (20190201)
G16C 20/50 (20190201)
G16C 20/60 (20190201)
G16C 20/62 (20190201)
G16C 20/64 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111306 Durum et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Scott Durum (Frederick, Maryland);  Julie Hixon (Hagerstown, Maryland);  Wen Qing Li (Frederick, Maryland);  Scott Walsh (College Park, Maryland);  Lila Kashi (College Park, Maryland)
ABSTRACT Antibodies and antigen binding fragments that specifically bind to IL-7Rα are disclosed. Nucleic acids encoding the antibodies and antigen binding fragments, and vectors including the nucleic acid molecules are also provided. Methods for detecting a ca cancer or a cell that expresses IL-7Rα using the antibodies and antigen binding fragments are disclosed, as is the use of the antibodies and antigen binding fragments to prevent and/or treat a subject with a cancer that expresses IL-7Rα, such as acute lymphoblastic leukemia.
FILED Monday, July 01, 2019
APPL NO 16/459396
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2866 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/31 (20130101)
C07K 2317/51 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)
C07K 2317/567 (20130101)
C07K 2317/622 (20130101)
C07K 2317/732 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/7155 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111375 Rodrigues et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Gonçalo Rodrigues (Berkeley, California);  David V. Schaffer (Danville, California)
ABSTRACT The present disclosure provides a three-dimensional culture system comprising a biocompatible polymer and a combination of factors in an amount effective to induce differentiation of oligodendrocyte precursors and/or oligodendrocytes from pluripotent stem cells. The present disclosure provides methods of generating oligodendrocyte precursors and/or oligodendrocytes using a three-dimensional culture system of the present disclosure. The present disclosure provides methods to treat neurological diseases and demyelinating diseases.
FILED Tuesday, October 04, 2016
APPL NO 15/758231
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101)

Heterocyclic Compounds
C07D 471/04 (20130101)

Compositions of Macromolecular Compounds
C08L 51/006 (20130101) Original (OR) Class
C08L 2203/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0018 (20130101)
C12N 5/0622 (20130101)
C12N 2501/41 (20130101)
C12N 2501/385 (20130101)
C12N 2501/415 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2539/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111472 Sharei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Armon R. Sharei (Watertown, Massachusetts);  Shirley Mao (Cambridge, Massachusetts);  George Hartoularos (Boston, Massachusetts);  Sophia Liu (Boston, Massachusetts);  Megan Heimann (Baltimore, Maryland);  Pamela Basto (Somerville, Massachusetts);  Gregory Szeto (Baltimore, Maryland);  Siddharth Jhunjhunwala (Bengaluru, India);  Darrell Irvine (Arlington, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Klavs F. Jensen (Lexington, Massachusetts);  Ulrich H. Von Andrian (Chestnut Hill, Massachusetts)
ABSTRACT A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
FILED Friday, October 30, 2015
APPL NO 15/523142
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 45/06 (20130101)
A61K 49/0017 (20130101)
A61K 2039/5158 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 35/00 (20130101)
C12M 35/04 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0635 (20130101)
C12N 5/0636 (20130101)
C12N 5/0639 (20130101)
C12N 15/87 (20130101)
C12N 2501/05 (20130101)
C12N 2501/998 (20130101)
C12N 2510/00 (20130101)
C12N 2527/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111478 Gattinoni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Luca Gattinoni (Washington, District of Columbia);  Enrico Lugli (Bethesda, Maryland);  Mario Roederer (Washington, District of Columbia);  Nicholas P. Restifo (Chevy Chase, Maryland)
ABSTRACT Provided are methods of producing an isolated T memory stem cell population, the method comprising a) isolating naïve T cells from a mammal, wherein the mammal is not a mouse; b) activating the naïve T cells and expanding the numbers of naïve T cells in the presence of one or more non-specific T cell stimuli, one or more cytokines, and a GSK-3beta inhibitor. Also provided are methods of producing an isolated T memory stem cell population, the method comprising a) isolating lymphocytes from a mammal; b) sorting the lymphocytes using flow cytometry into a population comprising a phenotype comprising i) CD95+, CD45RO−, and CCR7+; and ii) CD62L+ or one or more of CD27+, CD28+, CD45RA+, and CD127+ to produce an isolated T memory stem cell population. Further embodiments of the invention provide related cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer.
FILED Monday, May 13, 2019
APPL NO 16/410327
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 2039/572 (20130101)
A61K 2039/5158 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 2501/51 (20130101)
C12N 2501/415 (20130101)
C12N 2501/515 (20130101)
C12N 2501/727 (20130101)
C12N 2501/2302 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111484 Fischetti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Vincent A. Fischetti (New York, New York);  Jonathan Schmitz (New York, New York);  Daniel Gilmer (New York, New York);  Chad Euler (New York, New York)
ABSTRACT The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.
FILED Monday, December 09, 2019
APPL NO 16/707733
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/47 (20130101)
A61K 38/50 (20130101)
A61K 38/162 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2462 (20130101) Original (OR) Class

Enzymes
C12Y 302/01017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111492 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Hong Li (Tallahassee, Florida);  Martin Tsui (Tallahassee, Florida);  Travis Hand (Tallahassee, Florida)
ABSTRACT Described herein are methods and compositions for rapid and precise genome editing at any desired genomic position in almost all cells and organisms. The methods utilize a cytosine-specific Cas9 endonuclease and are suitable for applications requiring targeting cytosine adjacent DNA. The methods generally include introducing a cytosine-specific Cas9 endonuclease, a single guide RNA, and optionally a DNA repair template that is utilized in either non-homologous end joining or homology directed repair. The methods can be used to effect gene knockout, gene knockdown, gene substitution, or gene introduction in cells and organisms.
FILED Tuesday, March 06, 2018
APPL NO 15/913444
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111514 Mitra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Robi M. Mitra (St. Louis, Missouri);  Katherine E. Varley (St. Louis, Missouri)
ABSTRACT The invention encompasses a method for amplifying at least two different nucleic acid sequences. In particular, the method encompasses a multiplexed nucleic acid patch polymerase chain reaction.
FILED Friday, January 19, 2018
APPL NO 15/875027
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 2521/325 (20130101)
C12Q 2521/531 (20130101)
C12Q 2535/122 (20130101)
C12Q 2549/119 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111519 Abate et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam R. Abate (San Francisco, California);  John R. Haliburton (San Francisco, California);  Freeman Lan (San Francisco, California);  Adam R. Sciambi (San Francisco, California)
ABSTRACT Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, e.g., via nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet-based methods of preparing nucleic acid barcodes for use in various barcoding applications. The methods described herein facilitate high-throughput sequencing of nucleic acid target molecules as well as single cell and single virus genomic, transcriptomic, and/or proteomic analysis/profiling. Systems and devices for practicing the subject methods are also provided.
FILED Wednesday, February 03, 2016
APPL NO 15/015015
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 1/00 (20130101)
B01F 5/0655 (20130101)
B01F 13/0071 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101)
B01L 7/52 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/021 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0424 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6874 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/179 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111521 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Je-hyuk Lee (Allston, Massachusetts);  Richard C. Terry (Carlisle, Massachusetts);  Evan R. Daugharthy (Cambridge, Massachusetts)
ABSTRACT Methods of making a three-dimensional matrix of nucleic acids within a cell is provided.
FILED Tuesday, December 15, 2020
APPL NO 17/122168
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6844 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111527 Kanavarioti
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Anastassia Kanavarioti (El Dorado Hills, California)
ASSIGNEE(S)
INVENTOR(S) Anastassia Kanavarioti (El Dorado Hills, California)
ABSTRACT Provided for herein is a method for detecting the presence of a nucleic acid target molecule in a biological sample. In certain aspects, the method comprises contacting a test sample that comprises (i) a biological sample comprising a nucleic acid target molecule and (ii) an osmylated single-stranded oligonucleotide probe comprising at least one pyrimidine residue covalently bonded to a substituted or unsubstituted Osmium tetroxide (OsO4)-2,2′-bypyridine group (OsBp group).
FILED Monday, October 05, 2020
APPL NO 17/063245
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6832 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111543 Rabinowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Natera, Inc. (San Carlos, California)
ASSIGNEE(S) Natera, Inc. (San Carlos, California)
INVENTOR(S) Matthew Rabinowitz (San Francisco, California);  Milena Banjevic (Los Altos Hills, California);  Zachary Demko (San Francisco, California);  David Johnson (San Francisco, California);  Dusan Kijacic (Los Altos Hills, California);  Dimitri Petrov (Stanford, California);  Joshua Sweetkind-Singer (San Jose, California);  Jing Xu (Jersey City, New Jersey)
ABSTRACT Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.
FILED Thursday, February 27, 2020
APPL NO 16/803739
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6876 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 25/00 (20190201)
G16B 30/00 (20190201)
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111544 Rabinowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Natera, Inc. (San Carlos, California)
ASSIGNEE(S) Natera, Inc. (San Carlos, California)
INVENTOR(S) Matthew Rabinowitz (San Francisco, California);  Milena Banjevic (Los Altos Hills, California);  Zachary Demko (San Francisco, California);  David Johnson (San Francisco, California);  Dusan Kijacic (Los Altos Hills, California);  Dimitri Petrov (Stanford, California);  Joshua Sweetkind-Singer (San Jose, California);  Jing Xu (Jersey City, New Jersey)
ABSTRACT Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.
FILED Wednesday, March 18, 2020
APPL NO 16/823127
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6827 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6876 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2537/149 (20130101)
C12Q 2545/114 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 25/00 (20190201)
G16B 30/00 (20190201)
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112409 Nobile et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Clarissa Nobile (Oakland, California);  Michael Winter (Oakland, California);  Charles Craik (Oakland, California);  Alexander Johnson (Oakland, California);  Anthony O'Donoghue (Oakland, California)
ABSTRACT The present disclosure relates generally to detection of contamination of a sample or diagnosis of subject based upon detection or quantification of amino acid sequences in a sample, specifically to the identification and use of molecular biomarkers for Candida albicans biofilm infections.
FILED Friday, February 10, 2017
APPL NO 16/077690
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/48 (20130101)
C12N 9/60 (20130101)

Enzymes
C12Y 304/23024 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56961 (20130101) Original (OR) Class
G01N 2333/40 (20130101)
G01N 2333/96 (20130101)
G01N 2333/8142 (20130101)
G01N 2333/96416 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112472 Ruyters et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Gudrun Ruyters (Erlangen, Germany);  Andrew Dewdney (Neunkirchen am Brand, Germany);  Manuel Stich (Parkstein, Germany);  Herbert Köstler (Retzbach, Germany);  Christiane Pfaff (Unterebersbach, Germany);  Tobias Wech (Würzburg, Germany);  Adrienne Campbell (Bethesda, Maryland)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  Julius-Maximilians-Universität Würzburg (Würzburg, Germany);  THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Gudrun Ruyters (Erlangen, Germany);  Andrew Dewdney (Neunkirchen am Brand, Germany);  Manuel Stich (Parkstein, Germany);  Herbert Köstler (Retzbach, Germany);  Christiane Pfaff (Unterebersbach, Germany);  Tobias Wech (Würzburg, Germany);  Adrienne Campbell (Bethesda, Maryland)
ABSTRACT A gradient system characterization function (e.g., a gradient system transfer function) may be developed by measuring a behavior of the MR device at a target temperature and developing at least one gradient system characterization function for a gradient coil of a magnetic resonance (MR) device at the target temperature based on the measured behavior. A patient may be subsequently imaged by the MR device, wherein the imaging process comprises measuring a temperature of a gradient coil, determining a gradient system characterization function at the measured temperature, calculating a pre-emphasized gradient of the gradient coil, and imaging the patient using the pre-emphasized magnetic field component.
FILED Friday, November 29, 2019
APPL NO 16/699415
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/3852 (20130101)
G01R 33/3856 (20130101) Original (OR) Class
G01R 33/56572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112592 Feldman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana)
ASSIGNEE(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Martin Feldman (Baton Rouge, Louisiana)
ABSTRACT According to some embodiments of the present invention, a fine focus microscope includes an objective lens for collecting light from an object being imaged, and a tube lens for forming a first image from light received from the objective lens. The fine focus microscope further includes a fine focus lens for forming a second image from the first image, and an eyepiece for forming a third image from the second image, wherein the third image is viewable by a user. The fine focus microscope further includes a field lens for directing light from the second image to the eyepiece, and a positioning system mechanically coupled to the fine focus lens, the eyepiece, and the field lens. The positioning system changes a position of the fine focus lens, the eyepiece, and the field lens with respect to the objective lens to provide a change in focus of the object being imaged.
FILED Friday, April 22, 2016
APPL NO 15/136465
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/44 (20130101)
G01J 3/0208 (20130101)
G01J 3/0237 (20130101)
G01J 3/0256 (20130101)
G01J 3/0272 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/02 (20130101)
G02B 21/242 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112594 Ouzounov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Dimitre G Ouzounov (Ithaca, New York);  Chunhui (Chris) Xu (Ithaca, New York);  Watt W. Webb (Ithaca, New York)
ABSTRACT A microendoscope, and a microendoscopy method related to the microendoscope, each include a tube housing, where an end of the tube housing is shaped and finished to facilitate collection of light emitted from a sample when examined using the microendoscope. In addition, a catadioptric lens assembly, an endomicroscope that includes the catadioptric lens assembly and a microendoscopy method for microscopic analysis that uses the endomicroscope are predicated upon a second element and a third element within the catadioptric lens assembly that each has a dichroic coating. The placement of the dichroic coating on the second element and the third element provides for different magnification factors as a function of illumination wavelength when using the microendoscopy method.
FILED Friday, May 10, 2013
APPL NO 14/400257
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/043 (20130101)
A61B 1/00096 (20130101)
A61B 1/00188 (20130101)
A61B 1/0638 (20130101)

Optical Elements, Systems, or Apparatus
G02B 17/0896 (20130101)
G02B 21/06 (20130101)
G02B 21/16 (20130101)
G02B 23/2438 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114184 Schramm et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Albert Einstein College of Medicine (Bronx, New York)
ASSIGNEE(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
INVENTOR(S) Vern L. Schramm (New Rochelle, New York);  Quan Du (Bronx, New York);  Zhen Wang (Feicheng, China PRC)
ABSTRACT Methods and systems for obtaining inhibitors of human DNA methyltransferase 1 (DNMT1) are disclosed where the methods involve designing compounds that resemble the DNMT1 transition state.
FILED Tuesday, February 13, 2018
APPL NO 15/895057
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1007 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/48 (20130101)

Enzymes
C12Y 201/01037 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/10 (20190201)
G16C 20/50 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115045 Furenlid et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Lars R. Furenlid (Tucson, Arizona);  Maria Ruiz-Gonzalez (Tucson, Arizona)
ABSTRACT A delta sigma modulator includes a summation circuit, at least one integrator, a multi-bit quantizer and a negative feedback circuit. The summation circuit is configured to produce a difference signal between an analog input signal and an analog feedback signal. The integrator is operatively coupled to the summation circuit to integrate the difference signal. The multi-bit quantizer is operatively coupled to the integrator to digitize the integrated signal to generate an N-bit digital output signal, N being an integer greater than 1. The negative feedback circuit operatively couples the multi-bit quantizer to the summation circuit. The negative feedback circuit includes a digital-to-analog converter arrangement for receiving the N-bit digital output signal and providing the analog feedback signal such that digital values of the N-bit digital output signal and values of the analog feedback encoded by the digital values have a non-linear relationship to one another.
FILED Thursday, October 25, 2018
APPL NO 16/759531
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 3/424 (20130101) Original (OR) Class
H03M 3/464 (20130101)
H03M 3/496 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11109771 Pierro
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Vivonics, Inc. (Bedford, Massachusetts)
ASSIGNEE(S) Vivonics, Inc. (Bedford, Massachusetts)
INVENTOR(S) Michele Pierro (Westford, Massachusetts)
ABSTRACT A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes at least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space. A processing subsystem is coupled to the at least one intracranial light source, the at least one extracranial light source, and the detector subsystem. The processing subsystem is configured to determine intracranial oxygen saturation and extracranial oxygen saturation and non-invasively determine an indication and/or an assessment of ICP using a ratio of the intracranial oxygen saturation to the extracranial oxygen saturation.
FILED Thursday, December 31, 2020
APPL NO 17/139092
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/031 (20130101) Original (OR) Class
A61B 5/0059 (20130101)
A61B 5/6814 (20130101)
A61B 5/14542 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109784 Adalian et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Dvin Adalian (Pasadena, California);  Samson Chen (Pasadena, California);  Muhammad M. Jilani (Pasadena, California);  Axel Scherer (Pasadena, California);  Xiomara Linnette Madero (Pasadena, California);  Richard Smith (Pasadena, California)
ABSTRACT Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.
FILED Wednesday, November 14, 2018
APPL NO 16/191357
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1473 (20130101)
A61B 5/14532 (20130101)
A61B 5/14546 (20130101)
A61B 5/14865 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109789 Bibian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Stéphane Bibian (Cleveland Heights, Ohio);  Tatjana Zikov (Cleveland Heights, Ohio);  Sankar Barua (Stow, Ohio)
ASSIGNEE(S) NeuroWave Systems Inc. (Cleveland, Ohio)
INVENTOR(S) Stéphane Bibian (Cleveland Heights, Ohio);  Tatjana Zikov (Cleveland Heights, Ohio);  Sankar Barua (Stow, Ohio)
ABSTRACT A system and method for using electroencephalographic (EEG) signals to monitor brain function, preferably detect occurrence of traumatic brain injury (TBI) to screen, assess, and potentially provide mitigating treatment to improve short and long term adverse outcomes of mild TBI (mTBI) and TBI. The system and method provides a readily available tool to assist in accurate and objective assessment of subjects with TBI, immediately at the point of injury (POI), during transportation, or upon arrival at a care facility, that preferably is applicable without advanced training or expertise.
FILED Thursday, August 08, 2013
APPL NO 13/962533
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/291 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11109865 Horava et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Triton Systems, Inc. (Chelmsford, Massachusetts)
ASSIGNEE(S) TRITON SYSTEMS, INC. (Chelmsford, Massachusetts)
INVENTOR(S) Sarena Horava (Medway, Massachusetts);  Yoojeong Kim (Sudbury, Massachusetts);  Anant Singh (Woburn, Massachusetts)
ABSTRACT A device may include a shaft with a dispensing channel, an evacuating channel, a proximal end, and a distal end. The device may further include an enclosure attached to the distal portion of the shaft, the enclosure having a first portion and a second portion that form a bore when the enclosure is closed. The device may further include a handle attached to the proximal end of the shaft, which is configured to open and close the enclosure. A method of delivering a solution to a nerve repair site may include obtaining such a device, closing its enclosure around the nerve repair site, delivering one or more solutions through the dispensing channel to the nerve repair site, removing one or more solutions through the evacuating channel from the nerve repair site, and opening the enclosure to remove it from the nerve repair site.
FILED Monday, July 23, 2018
APPL NO 16/042413
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1128 (20130101) Original (OR) Class
A61B 2017/00004 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/30 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/383 (20130101)
A61L 27/3675 (20130101)
A61L 27/3878 (20130101)
A61L 2430/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110681 Cockeram
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Naval Nuclear Laboratory (NNL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Brian V. Cockeram (West Mifflin, Pennsylvania)
ABSTRACT Disclosed is a hermetic bond for a joint including a first layer of silicon carbide; a second layer of silicon carbide; and a bonding layer positioned between the first layer and the second layer, wherein the bonding layer includes an iridium layer, a first reaction zone positioned between the iridium foil layer and the first layer, and a second reaction zone positioned between the iridium foil layer and the second layer, wherein the first reaction zone and the second reaction zone include iridium silicides.
FILED Thursday, June 27, 2019
APPL NO 16/454240
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/0008 (20130101)
B23K 2101/04 (20180801)
B23K 2103/52 (20180801)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 1/08 (20130101) Original (OR) Class
B32B 15/04 (20130101)
B32B 37/10 (20130101)
B32B 2309/02 (20130101)
B32B 2309/04 (20130101)
B32B 2309/12 (20130101)
B32B 2309/68 (20130101)
B32B 2309/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110763 Pavlov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
ASSIGNEE(S) Government of the United States, as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kirill Pavlov (Southfield, Michigan);  William E. Johnson (Davison, Michigan)
ABSTRACT One example embodiment is a tow bar retention mechanism for a vehicle tow bar of a combat vehicle. The tow bar retention mechanism includes a tow bar retention arm, an elongated locking beam, a quick-release locking mechanism, and a quick-release safety mechanism. The quick-release locking mechanism locks the tow bar retention arm in a locked position placing the vehicle tow bar in a stowed position. The quick-release locking mechanism also unlocks the tow bar retention arm allowing the tow bar retention arm to move to an unlocked position allowing the vehicle tow bar to move to a tow position. The quick-release safety mechanism may be placed in a first position preventing the quick-release locking mechanism from moving from the locked position. The quick-release safety mechanism may also be placed in a second position allowing the quick-release locking mechanism to move from the locked position.
FILED Thursday, April 11, 2019
APPL NO 16/381311
ART UNIT 3611 — Miscellaneous Articles, Stock Material
CURRENT CPC
Vehicle Connections
B60D 1/02 (20130101)
B60D 1/54 (20130101) Original (OR) Class
B60D 1/155 (20130101)
B60D 2001/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110784 Flaxman
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
United States Army (USA)
APPLICANT(S) QinetiQ Limited (Hampshire, United Kingdom)
ASSIGNEE(S) QINETIQ LIMITED (Hampshire, United Kingdom)
INVENTOR(S) Robert John Bonner Flaxman (Guildford, United Kingdom)
ABSTRACT Some embodiments are directed to a drive configuration for a skid-steered vehicle that has a pair of traction motors for rotationally driving opposite outputs of the drive configuration. The traction motors are operatively connected to the outputs via respective gearing arrangements for selectively varying gear reduction between each of the traction motors and the corresponding output. The drive configuration also has a steer differential in a torque connection with the first and second outputs of the drive configuration. The drive configuration additional has a steer motor operatively connected to the steer differential for selectively varying the rotational speed of the first and second outputs in use. Also, the traction and steer motors define a volume in which the gearing arrangements and steering differential are at least partially located.
FILED Friday, September 01, 2017
APPL NO 16/346729
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 1/02 (20130101) Original (OR) Class
B60K 6/445 (20130101)
B60K 17/08 (20130101)
B60K 17/046 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 15/2036 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/25 (20130101)
B60Y 2400/85 (20130101)

Motor Vehicles; Trailers
B62D 11/14 (20130101)

Gearing
F16H 2048/364 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111031 Dunlay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) Rockwell Collins, Inc. (Cedar Rapids, Iowa)
ASSIGNEE(S) Rockwell Collins, Inc. (Cedar Rapids, Iowa)
INVENTOR(S) Angela N. Dunlay (Marion, Iowa);  Steven L. Kamada (Cedar Rapids, Iowa);  Phillip J. Hamm (Cedar Rapids, Iowa)
ABSTRACT A touchscreen fuel panel. In embodiments, the fuel panel includes a touchscreen display and a controller coupled to the touchscreen display. The controller is configured to generate a graphical user interface at the touchscreen display and receive user inputs via the touchscreen display. In embodiments, the graphical user interface includes a pump menu with at least one selectable icon for a set of engine boost pumps and a plurality of individually selectable icons for forward, center, and aft pumps. The controller is configured to receive a user input representing a user interaction with the graphical user interface (e.g., an icon selection) via the touchscreen display. The controller is further configured to generate one or more control signals for the set of engine boost pumps, at least one forward pump, at least one center pump, or at least one aft pump based on the user input.
FILED Thursday, October 03, 2019
APPL NO 16/592256
ART UNIT 2178 — Graphical User Interface and Document Processing
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 37/005 (20130101)
B64D 43/00 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/0482 (20130101)
G06F 3/0488 (20130101)
G06F 3/04817 (20130101)

Image Data Processing or Generation, in General
G06T 11/001 (20130101)
G06T 13/80 (20130101)
G06T 2200/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111378 Moore et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jeffrey S. Moore (Savoy, Illinois);  Scott R. White (Champaign, Illinois);  Nancy R. Sottos (Champaign, Illinois);  Adam M. Feinberg (Urbana, Illinois);  Christopher L. Plantz (Urbana, Illinois);  Hector Lopez-Hernandez (Urbana, Illinois);  Evan M. Lloyd (Urbana, Illinois)
ABSTRACT The present disclosure provides a composition of matter comprising purified cyclic poly(phthalaldehyde) (cPPA) and a plasticizer. The composition enables thermal processing and molding in bulk quantities, and is designed to degrade when contacted by an acid or exposed to a high enough temperature. Photodegradable cPPA containing a photooxidant is disclosed. Methods of making and recycling the composition of matter are also provided.
FILED Friday, April 12, 2019
APPL NO 16/383316
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 27/10 (20130101)
B01J 27/135 (20130101)
B01J 27/138 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/005 (20130101)
C08K 5/06 (20130101)
C08K 5/12 (20130101)
C08K 5/0016 (20130101)
C08K 5/18 (20130101)
C08K 5/3432 (20130101)

Compositions of Macromolecular Compounds
C08L 61/02 (20130101) Original (OR) Class
C08L 2201/08 (20130101)
C08L 2203/16 (20130101)
C08L 2203/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111519 Abate et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam R. Abate (San Francisco, California);  John R. Haliburton (San Francisco, California);  Freeman Lan (San Francisco, California);  Adam R. Sciambi (San Francisco, California)
ABSTRACT Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, e.g., via nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet-based methods of preparing nucleic acid barcodes for use in various barcoding applications. The methods described herein facilitate high-throughput sequencing of nucleic acid target molecules as well as single cell and single virus genomic, transcriptomic, and/or proteomic analysis/profiling. Systems and devices for practicing the subject methods are also provided.
FILED Wednesday, February 03, 2016
APPL NO 15/015015
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 1/00 (20130101)
B01F 5/0655 (20130101)
B01F 13/0071 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101)
B01L 7/52 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/021 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0424 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6874 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/179 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112115 Kostka, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Stanislav Kostka, Jr. (Middletown, Connecticut);  Randal G. McKinney (Ellington, Connecticut);  James B. Hoke (Tolland, Connecticut);  Timothy S. Snyder (Glastonbury, Connecticut);  Frank J. Cunha (Avon, Connecticut)
ABSTRACT A wall assembly for use in a combustor of a gas turbine engine includes a support shell with a first inner periphery along an axis and a liner panel with a second inner periphery along the axis. The second inner periphery is smaller than the first inner periphery. Another wall assembly for use in a combustor of a gas turbine engine includes an annular grommet mounted between the support shell and the liner panel. The annular grommet defines a contoured inner wall.
FILED Monday, June 30, 2014
APPL NO 14/910827
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101)
F23R 3/04 (20130101)
F23R 3/06 (20130101) Original (OR) Class
F23R 3/26 (20130101)
F23R 3/045 (20130101)
F23R 2900/03041 (20130101)
F23R 2900/03044 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112145 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Ying Liu (Claredon Hills, Illinois);  Alexander Donovan (Glencoe, Illinois)
ABSTRACT Artificial dense granules composed of a sterically stabilized liposome shell encapsulating a polyphosphate nanoparticle core are provided as are methods for their production and use in the treatment of a severe hemorrhagic event.
FILED Thursday, September 24, 2015
APPL NO 15/513752
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1271 (20130101)
A61K 9/1278 (20130101)
A61K 33/42 (20130101)
A61K 38/36 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/04 (20180101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 49/005 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 9/04 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 23/1919 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112213 Gieseke
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Thomas J Gieseke (Warren, Rhode Island)
ABSTRACT An adapter cage is provided for a compressed gas launcher to multiply launch velocity. Kinematics of wheels integral to the adapter cage results in a doubling of the pusher plate velocity as that motion is imparted on a light-weight launch vehicle. The wheels of the adapter cage can press against the launch vehicle and the wheels are pressed against the walls of the launcher for employing friction at the interface of the wheels and the inner surface of the launcher to transfer motion to force out a muzzle cap of the launcher and to enable launch of the launch vehicle.
FILED Friday, February 07, 2020
APPL NO 16/784280
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 11/73 (20130101)

Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns
F41F 3/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112245 Piazza et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Precise Robust Inertial Guidance for Munitions Advanced Inertial Micro Sensors (PRIGM-AIMS)
Department of the Navy (DON)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Gianluca Piazza (Pittsburgh, Pennsylvania);  Mohamed Mahmoud (Pittsburgh, Pennsylvania);  Ashraf Mahmoud (Pittsburgh, Pennsylvania);  Lutong Cai (Pittsburgh, Pennsylvania);  Md Shofiqul Islam Khan (Pittsburgh, Pennsylvania);  Tamal Mukherjee (Pittsburgh, Pennsylvania);  James Bain (Pittsburgh, Pennsylvania)
ABSTRACT An Acousto-Optic Gyroscope (AOG) consisting of a photonic integrated device embedded into two inherently matched piezoelectric surface acoustic wave (SAW) resonators sharing the same acoustic cavity is disclosed. The micromachined strain-based AOG uses the effective index of the optical waveguide due to the acousto-optic effect rather than conventional displacement sensing.
FILED Wednesday, October 03, 2018
APPL NO 16/151010
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/5698 (20130101) Original (OR) Class

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 9/004 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112246 Blankenship
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Secretary of the Army (SECARMY)
APPLICANT(S) UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
ASSIGNEE(S) United States Government as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Clinton Blankenship (Redstone Arsenal, Alabama)
ABSTRACT A resonant mechanical structure, such as one for use in a torsional oscillator MEMS accelerometer that includes a mounting substrate and a reference mass configured to move within a reference mass plane, the resonant mechanical structure being connected to the mounting structure and the reference mass, and the resonant mechanical structure including a body, a center of mass, and an aperture, wherein the aperture is surrounded and defined by the body, and wherein the body includes a first mass portion and a second mass portion that are configured to oscillate about an oscillation axis located within the reference mass plane, wherein the center of mass is located on the oscillation axis, and wherein a movement of the reference mass within the reference mass plane varies a moment of inertia of the body while the center of mass of the body remains located on the oscillation axis.
FILED Friday, June 14, 2019
APPL NO 16/442112
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/5712 (20130101) Original (OR) Class

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/14 (20130101)
G01P 15/18 (20130101)
G01P 15/097 (20130101)
G01P 15/0802 (20130101)
G01P 2015/0825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112305 Jarrahi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Space and Naval Warfare Systems (SPAWAR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Mona Jarrahi (Los Angeles, California);  Christopher W. Berry (Mountain View, California);  Ning Wang (Mountain View, California)
ABSTRACT A photoconductive device that includes a semiconductor substrate, an antenna assembly, and a photoconductive assembly with one or more plasmonic contact electrodes. The photoconductive assembly can be provided with plasmonic contact electrodes that are arranged on the semiconductor substrate in a manner that improves the quantum efficiency of the photoconductive device by plasmonically enhancing the pump absorption into the photo-absorbing regions of semiconductor substrate. In one exemplary embodiment, the photoconductive device is arranged as a photoconductive source and is pumped at telecom pump wavelengths (e.g., 1.0-1.6 μm) and produces milliwatt-range power levels in the terahertz (THz) frequency range.
FILED Tuesday, October 24, 2017
APPL NO 15/792575
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/108 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/09 (20130101)
H01L 31/0224 (20130101)
H01L 31/02327 (20130101)
H01L 31/035209 (20130101)
H01L 33/04 (20130101)
H01L 33/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112360 Shepard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Kenneth Shepard (Ossining, New York);  Girish Ramakrishnan (New York, New York)
ABSTRACT Systems and methods for performing non-destructive sensing of a cell or tissue, in vivo or in culture, are provided. The disclosed systems and methods include fabricating and powering one or more implantable integrated circuit (IC) chips that include a network of Photovoltaic (PV) cells for energy harvesting from an optical energy source, an optical modulator integrating Quantum Dot capacitors (QD-caps) for optical data transfer using fluorescence modulation, and sensing circuitry. The IC chip disclosed herein can measure a thickness of around 10 μm, allowing injection into small cells and diffusion through tissue, it is powered and imaged under a microscope and communicates using fluorescence modulation imaged under a microscope.
FILED Friday, July 20, 2018
APPL NO 16/041373
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 2560/0214 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/025 (20130101)
G02F 1/0157 (20210101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02327 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112410 Kang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Joo-Hun Kang (Boston, Massachusetts);  Donald E. Ingber (Boston, Massachusetts);  Michael Super (Lexington, Massachusetts);  Alexander L. Watters (North Andover, Massachusetts);  Harry Scott Driscoll (Allston, Massachusetts)
ABSTRACT The invention relates to methods of detection, capture, isolation and targeting of cancer cells for example circulating tumor cells (CTCs) using carbohydrate recognition domain of a lectin. The invention relates to methods of diagnosis, prognosis and treatment of cancer.
FILED Monday, April 10, 2017
APPL NO 16/092288
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 47/6415 (20170801)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101) Original (OR) Class
G01N 2333/71 (20130101)
G01N 2333/705 (20130101)
G01N 2333/4724 (20130101)
G01N 2333/4725 (20130101)
G01N 2400/00 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112454 Sertel
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Kubilay Sertel (Hilliard, Ohio)
ABSTRACT Described herein are antenna-coupled radio frequency (RF) probes with replaceable tips. In the described embodiments, test signals are coupled onto a probe tip wafer via an on-tip antenna, thus the probe tip is decoupled from the probe body. This allows for separate fabrication of the probe body and the probe tip. As such, the probe tip can be made available as a “commodity” and the user can simply replace a worn-out or damaged probe tip, providing significant savings in per-unit cost and operation cost of the new contact probes. The decoupling of probe tip and probe body allows for manual replacement of probe tip without the need for extremely accurate alignment which is typically required in extremely high frequency probes. Manual replacement of the tips is only possible due to the much less stringent alignment requirements afforded by the antenna coupling from the probe body to the probe tip.
FILED Wednesday, November 15, 2017
APPL NO 16/461208
ART UNIT 2868 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/06772 (20130101)
G01R 31/3025 (20130101) Original (OR) Class

Antennas, i.e Radio Aerials
H01Q 19/06 (20130101)
H01Q 19/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112503 Fried et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
U.S. Air Force
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Dale G. Fried (Dover, Massachusetts);  Jonathan P. Frechette (Marlborough, Massachusetts)
ABSTRACT A method of imaging a scene includes estimating multiple three-dimensional (3D) representations, each of which corresponds to a respective portion of the scene. Neighboring portions of the scene area are at least partially overlapping. Each 3D representation is estimated by illuminating the respective portion of the scene with a light burst including multiple light pulses, after which multiple point clouds are generated by detecting photons reflected or scattered from the respective portion of the scene using a focal plane array. Data points in the point clouds represent a distance between the focal plane array and a scene point in the respective portion of the scene. The 3D representation is then estimated based on the multiple point clouds via coincidence processing. The method then generates a 3D image of the scene based on the multiple 3D representations.
FILED Thursday, January 25, 2018
APPL NO 15/880223
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/481 (20130101)
G01S 7/4863 (20130101)
G01S 17/10 (20130101)
G01S 17/42 (20130101)
G01S 17/86 (20200101)
G01S 17/89 (20130101) Original (OR) Class
G01S 17/90 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112564 Steinbrecher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Gregory R. Steinbrecher (Brookline, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT A method of nonblocking optical switching includes guiding a first optical beam from a first input to a first output via a first path through an optical switching fabric. The first path traverses a phase shifter disposed between a pair of cascaded Mach-Zehnder interferometers. The method also includes receiving a second optical beam for a second path intersecting with the first path through the optical switching fabric. The method also includes moving the first optical beam from the first path to a third path connecting the first input to the first output without intersecting the second path. The method also includes shifting a phase of the first optical beam, with the phase shifter, while moving the first optical beam from the first path to the third path to prevent the first optical beam from interfering with the second optical beam.
FILED Tuesday, March 24, 2020
APPL NO 16/827795
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/356 (20130101) Original (OR) Class
G02B 6/3546 (20130101)
G02B 6/29355 (20130101)

Selecting
H04Q 11/0005 (20130101)
H04Q 2011/0015 (20130101)
H04Q 2011/0035 (20130101)
H04Q 2011/0047 (20130101)
H04Q 2011/0052 (20130101)
H04Q 2011/0058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113588 Rubin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretry of the Navy (Washington, District of Columbia)
INVENTOR(S) Stuart Harvey Rubin (San Diego, California)
ABSTRACT An object in a digital image is automatically recognized by obtaining the digital image, generating a first vector representation of a plurality of pixels of the obtained digital image, randomizing the first vector representation to generate a first generalized vector representation of the digital image that is substantially an order of magnitude smaller than the first vector representation, and searching a repository of hierarchically generalized vector representations of previously recognized digital images, to determine whether the first generalized vector representation of the digital image matches one or more of the previously recognized digital images, within a predetermined threshold value, based on determining a focus area within the obtained digital image, using associative memory.
FILED Wednesday, October 02, 2019
APPL NO 16/590832
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/32 (20130101)
G06K 9/6201 (20130101)
G06K 9/6255 (20130101)
G06K 9/6256 (20130101)
G06K 9/6807 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113614 Gerken et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
United States Air Force (USAF)
APPLICANT(S) Intelligent Software Solutions, Inc. (Colorado Springs, Colorado)
ASSIGNEE(S) PARSONS CORPORATION (Centreville, Virginia)
INVENTOR(S) Mark Gerken (Colorado Springs, Colorado);  Rick Pavlik (Colorado Springs, Colorado)
ABSTRACT Enterprise Hypothesis Orchestration provides users an intuitive system for building an inquiry model that thereafter creates and evaluates each of a plurality of hypotheses as it continuously searches for evidence to formulate, score, and resolve each hypothesis. The Enterprise Hypothesis Orchestration system moreover continuously deals with the uncertainty caused by noisy, missing, inaccurate, and/or contradictory data. The present invention uses abductive reasoning to infer the best explanation or hypothesis for a set of observations. Given an inquiry the Hypothesis Orchestration System identifies relevant data from which to form a plurality of hypotheses. It thereafter collects evidence in support of each hypothesis and crafts a degree of confidence that the hypothesis is true. If a hypothesis is found to lack support an analysis of any missing evidence is conducted to identify and seek which evidence would offer the highest benefit to resolving one or more of the plurality of hypotheses.
FILED Wednesday, July 27, 2016
APPL NO 15/221007
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 16/90335 (20190101)
G06F 2216/03 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/041 (20130101) Original (OR) Class
G06N 5/048 (20130101)
G06N 7/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113621 Cortese et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
U.S. Air Force
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John Cortese (Reading, Massachusetts);  Timothy Braje (Winchester, Massachusetts)
ABSTRACT Quantum circuits and methods load N=2n classical bits into an entangled quantum output state using a gate depth of order O(n). Loading is accomplished by dividing the 2n input bits into data words and entangling these data words using ancilla qubits. The output of the circuit consists of one data word and one or several index qubits, drawn from the ancilla, to select between the input data words. Entanglement of the data words is performed in a single time slice (i.e. with a gate depth of 1), while the number of sequential gates needed to produce the appropriate pre-entanglement quantum state in the ancilla, and to disentangle the non-output ancilla, has the desired order O(n). Also disclosed is a circuit for disentangling qubits used to store non-output data words during processing.
FILED Friday, January 04, 2019
APPL NO 16/239983
ART UNIT 2896 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113622 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) University of Oregon (Eugene, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon)
INVENTOR(S) Hailin Wang (Eugene, Oregon);  Mark C. Kuzyk (Eugene, Oregon)
ABSTRACT Spin qubits are situated in mechanical resonators that are acoustically coupled with acoustic waveguides. The acoustic waveguides provide frequency dependent phonon propagation selected so that mechanical resonators adjacent to a selected mechanical resonator are acoustically coupled to the selected mechanical resonator in different acoustic frequency ranges. This configure permits directional transfer of quantum states between spins in spin-mechanical resonator and provides a scalable platform for spin-based quantum computing.
FILED Tuesday, March 05, 2019
APPL NO 16/293555
ART UNIT 2843 — AI & Simulation/Modeling
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 3/0029 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113905 Korchev et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Autonomous Sustainment Technologies for Rotorcraft Operations Electrical (ASTRO-E)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Dmitriy Korchev (Irvine, California);  Charles E. Martin (Thousand Oaks, California);  Tsai-Ching Lu (Thousand Oaks, California);  Steve Slaughter (Scottsdale, Arizona);  Alice A. Murphy (Mesa, Arizona);  Christopher R. Wezdenko (Mesa, Arizona)
ABSTRACT A fault detection system including one or more sensors onboard a vehicle to detect a characteristic of the vehicle and generate sensor signals corresponding to the characteristic, a processor onboard the vehicle to receive the sensor signals, generate one or more fast Fourier transform vectors based on the sensor signals so that the one or more fast Fourier transform vectors are representative of the characteristic, generate an analysis model from a time history of the fast Fourier transform vectors, and determine, using the analysis model, a degree to which the one or more fast Fourier transform vectors could have been generated by the analysis model, and an indicator to communicate an operational status of the vehicle to an operator or crew member of the vehicle based on the degree to which the one or more fast Fourier transform vectors could have been generated by the analysis model.
FILED Thursday, January 30, 2020
APPL NO 16/776867
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/085 (20130101)
G07C 5/0808 (20130101) Original (OR) Class
G07C 5/0816 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)
H04L 69/04 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113942 Wade et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Secretary of the Navy (SECNAV)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael Wade (Ijamsville, Maryland);  Garry E. Shields (Ashburn, Virginia);  Zbigniew J. Karaszewski (McLean, Virginia)
ABSTRACT Systems and apparatus are provided for monitoring and/or collecting data regarding environmental conditions and optionally personal health information, and generating warnings for a wearer based on acceptable limits for hazards. Using the collected data, the systems and apparatus communicate recommendations to the wearer to improve or maintain personal safety in the detected environment. Methods for monitoring environmental risks and generating warnings based on acceptable limits for hazards are also provided.
FILED Friday, August 14, 2020
APPL NO 16/993848
ART UNIT 2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114594 Chakraborty
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
United States Air Force (USAF)
APPLICANT(S) Arpan Chakraborty (Goleta, California)
ASSIGNEE(S) CreeLED, Inc. (Durham, North Carolina)
INVENTOR(S) Arpan Chakraborty (Goleta, California)
ABSTRACT A radiation emitting device comprising light scattering particles of different sizes that at least partially surround an emitter, improving the spatial color mixing and color uniformity of the device. Multiple sizes of light scattering particles are dispersed in a medium to at least partially surround a single- or multiple-chip polychromatic emitter package. The different sizes of light scattering particles interact with corresponding wavelength ranges of emitted radiation. Thus, radiation emitted over multiple wavelength ranges or sub-ranges can be efficiently scattered to eliminate (or intentionally create) spatially non-uniform color patterns in the output beam.
FILED Friday, August 24, 2007
APPL NO 11/895573
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 25/0753 (20130101)
H01L 33/54 (20130101)
H01L 33/56 (20130101) Original (OR) Class
H01L 33/58 (20130101)
H01L 33/504 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2933/0091 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2991 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114738 Allen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Secretary of the Air Force (SECAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (WPAFB, Ohio)
INVENTOR(S) Jeffery Allen (Niceville, Florida);  Monica Allen (Niceville, Florida);  Daniel Wasserman (Champaign, Illinois);  Brett Wenner (Springboro, Ohio)
ABSTRACT Embodiments of the invention provide a resonant circuit including an active material substrate excitable by photon energy. A busline having a single input and a single output is located on the active material substrate. A RF resonator geometry is located on the active material substrate in electrical communication with the busline. Application of photon energy to the active material substrate changes the resonance of the RF resonator geometry at room temperatures. Alternately, a resonant circuit is provided that include a passive material substrate. An active material thin film is located on the passive material substrate. A busline having a single input and a single output and a RF resonator geometry located on the active material thin film. The RF resonator geometry is in electrical communication with the busline. Application of photon energy to the active material thin film changes the resonance of the RF resonator geometry at room temperatures.
FILED Monday, August 13, 2018
APPL NO 16/101772
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/42 (20130101)
G01J 1/44 (20130101)
G01J 5/10 (20130101)
G01J 5/44 (20130101)
G01J 2001/4413 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/288 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/015 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/088 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114972 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Hui Li (Tallahassee, Florida);  Yu Zhang (Tallahassee, Florida);  Yanjun Shi (Tallahassee, Florida)
ABSTRACT An active reflected wave canceller (ARWC, or RWC) can attached to each phase at the output of a motor drive (i.e., inverter). The reflected wave canceller is generally comprised of a pulse generator and a power inductor. The power inductor is used to by-pass the load current, so it doesn't flow through the pulse generator. The pulse generator injects an accurately controlled nanoseconds narrow-width pulse into the system. The injected narrow pulse breaks the rising and falling edge of the inverter output voltage into two steps, which generates two traveling waves along the cable that cancel each other at the motor terminals.
FILED Friday, November 22, 2019
APPL NO 16/692222
ART UNIT 2846 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/32 (20130101)
H02M 7/53871 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 27/08 (20130101)
H02P 29/0241 (20160201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115027 Rylov
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Sergey Rylov (White Plains, New York)
ABSTRACT Techniques regarding a DSFQ logic family are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a dynamic single flux quantum logic circuit that has a self-resetting internal state and can be powered by direct current. Further, the self-resetting internal state can be characterized by two time constants.
FILED Thursday, April 16, 2020
APPL NO 16/850203
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/10 (20130101)

Pulse Technique
H03K 3/38 (20130101)
H03K 19/1952 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115095 Castañeda Fernandez et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Oscar Fernando Castañeda Fernandez (New York, New York);  Christoph Emanuel Studer (New York, New York)
ABSTRACT Finite-alphabet beamforming for multi-antenna wideband systems is provided. The combination of massive multi-user multiple-input multiple-output (MU-MIMO) technology and millimeter-wave (mmWave) communication enables unprecedentedly high data rates for radio frequency (RF) communications. In such systems, beamforming must be performed at extremely high rates over hundreds of antennas. For example, spatial equalization applies beamforming in the uplink to mitigate interference among user equipment (UEs) at a base station (BS). Finite-alphabet equalization provides a new paradigm that restricts the entries of a spatial equalization matrix to low-resolution numbers, enabling high-throughput, low-power, and low-cost equalization hardware. Similarly, precoding applies beamforming in the downlink to maximize the reception of a signal transmitted from a BS to a target UE. Finite-alphabet precoding can be applied in the downlink to similarly improve power and cost in precoding hardware.
FILED Thursday, March 05, 2020
APPL NO 16/809813
ART UNIT 2632 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0404 (20130101)
H04B 7/0452 (20130101)
H04B 7/0456 (20130101)
H04B 7/0617 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/0202 (20130101)
H04L 25/03936 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115290 Ramlall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Secretary of the Navy (SECNAV)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as Represented by the Secretary of the Navy. (Washington, District of Columbia)
INVENTOR(S) Rohan Yash Ramlall (San Diego, California);  Matthew Ralph Capella (San Diego, California)
ABSTRACT A device and method monitor integrity of a communication network. A local clock maintains a local time. A network interface receives time synchronization packets and associates with each the local time of receipt at the network interface. A processing system implements a neural network for classifying whether integrity of the communication network is compromised from originate, receive, and transmit values determined from the time synchronization packets. The originate value is a difference between the local time of the receipt of the request packet and a transmission timestamp of the request packet. The receive value is a difference between a reception timestamp of the request packet or the reply packet and the local time of the receipt of the request packet or the reply packet. The transmit value is a difference between the local time of the receipt of the reply packet and a transmission timestamp of the reply packet.
FILED Wednesday, January 08, 2020
APPL NO 16/737577
ART UNIT 2474 — Multiplex and VoIP
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/16 (20130101) Original (OR) Class
H04L 41/0622 (20130101)
H04L 45/023 (20130101)
H04L 61/2503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11110052 Khizroev et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Sakhrat Khizroev (Miami, Florida);  Tiffanie Stewart (Miami, Florida);  Abhignyan Nagesetti (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Sakhrat Khizroev (Miami, Florida);  Tiffanie Stewart (Miami, Florida);  Abhignyan Nagesetti (Miami, Florida)
ABSTRACT Methods and devices for three-dimensional navigation of magnetic nanoparticles are provided. A method can comprise introducing high-anisotropy magnetic nanoparticles to a mammal and directing the high-anisotropy magnetic nanoparticles towards a target region of the mammal. Direction control is achieved by subjecting the high-anisotropy magnetic nanoparticles to an alternating signal comprising a uniform magnetic field pulse having a strength greater than a coercivity of the high-anisotropy magnetic nanoparticles and a magnetic gradient pulse having a highest strength that is less than the coercivity of the high-anisotropy magnetic nanoparticles and a location of a lowest strength at the target region of the mammal, and the direction of the uniform magnetic field pulse being in an opposite direction of the magnetic gradient pulse.
FILED Tuesday, May 21, 2019
APPL NO 16/417898
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/0515 (20130101)
A61B 5/4839 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101) Original (OR) Class
A61K 41/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/004 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110148 Kaplan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Rina Sears (Pine Meadow, Connecticut);  Gordana Vunjak-Novakovic (New York, New York);  Lorenz Meinel (Niestetal, Germany)
ABSTRACT The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
FILED Thursday, May 17, 2018
APPL NO 15/981981
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1825 (20130101) Original (OR) Class
A61K 38/1841 (20130101)
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/56 (20130101)
A61L 27/227 (20130101)
A61L 27/3604 (20130101)
A61L 27/3847 (20130101)
A61L 27/3852 (20130101)
A61L 27/3895 (20130101)

Compositions of Macromolecular Compounds
C08L 89/00 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/00 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 4/02 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/29 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110176 Wen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Xin Wen (Alhambra, California)
ASSIGNEE(S) The Board of Trustees of the California State University (Long Beach, California)
INVENTOR(S) Xin Wen (Alhambra, California)
ABSTRACT Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of −20-60° C.).
FILED Wednesday, November 22, 2017
APPL NO 15/821671
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0221 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/28 (20130101)
A61K 47/42 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/04 (20130101)
C12N 9/96 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110400 Shull et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Kenneth R. Shull (Evanston, Illinois);  Kazi Sadman (Evanston, Illinois);  Qifeng Wang (Evanston, Illinois)
ABSTRACT Methods for making porous polyelectrolyte complex (PEC) films are provided. In an embodiment, such a method comprises coating the surface of a substrate with a polyelectrolyte (PE) coacervate mixture, the PE coacervate mixture comprising a cationic polymer, an anionic polymer, water, and a salt, the PE coacervate having a salt concentration; exposing the coating to an aqueous medium having another salt concentration, for a time to induce solidification of polyelectrolyte complexes (PECs) in the form of a PEC film having pores distributed throughout, wherein a difference Δ?C-M #191 between the salt concentration of the PE coacervate mixture and the salt concentration of the aqueous medium is selected to achieve a predetermined porosity for the porous PEC film.
FILED Wednesday, May 09, 2018
APPL NO 16/611347
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/027 (20130101)
B01D 61/145 (20130101)
B01D 61/147 (20130101)
B01D 67/0011 (20130101) Original (OR) Class
B01D 67/0023 (20130101)
B01D 69/02 (20130101)
B01D 71/28 (20130101)
B01D 2325/02 (20130101)
B01D 2325/18 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/28 (20130101)
B05D 1/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110597 Polygerinos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Panagiotis Polygerinos (Gilbert, Arizona);  Pham Huy Nguyen (Mesa, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Panagiotis Polygerinos (Gilbert, Arizona);  Pham Huy Nguyen (Mesa, Arizona)
ABSTRACT The present disclosure provides a soft poly-limb system, comprising a first actuator segment, a second actuator segment, and a third actuator segment forming the soft poly-limb. Each of the first actuator segment, the second actuator segment, and the third actuator segment may comprise a plurality of ring reinforced actuators. The soft poly-limb system may further comprise a control system whereby a user may control the soft poly-limb.
FILED Thursday, April 11, 2019
APPL NO 16/381637
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/54 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
B25J 9/06 (20130101) Original (OR) Class
B25J 9/142 (20130101)
B25J 9/1612 (20130101)
B25J 9/1694 (20130101)
B25J 13/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111142 Marker et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Gas Technology Institute (Des Plaines, Illinois)
ASSIGNEE(S) Gas Technology Institute (Des Plaines, Illinois)
INVENTOR(S) Terry Marker (Palos Heights, Illinois);  Jim Wangerow (Oak Park, Illinois);  Pedro Ortiz-Toral (Wheeling, Illinois);  Martin Linck (Roscoe, Illinois)
ABSTRACT Processes and catalysts for producing hydrogen by reforming methane are disclosed, which afford considerable flexibility in terms of the quality of the reformer feed. This can be attributed to the robustness of the noble metal-containing catalysts described herein for use in reforming, such that a number of components commonly present in methane-containing process streams can advantageously be maintained without conventional upgrading (pretreating) steps, thereby improving process economics. This also allows for the reforming of impure reformer feeds, even in relatively small quantities, which may be characterized as complex gas mixtures due to significant quantities of non-methane components. A representative reforming catalyst comprises 1 wt-% Pt and 1 wt-% Rh as noble metals, on a cerium oxide support.
FILED Tuesday, September 18, 2018
APPL NO 16/134623
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/40 (20130101) Original (OR) Class
C01B 2203/107 (20130101)
C01B 2203/0233 (20130101)
C01B 2203/0238 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111178 Wang
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama)
INVENTOR(S) Jialai Wang (Tuscaloosa, Alabama)
ABSTRACT Cementitious compositions comprising a hydraulic cementitious material, a compound selected from the group consisting of a polyhydroxy aromatic compound, a polycarboxylic acid-containing compound or a salt thereof, ascorbic acid or a salt thereof, or a combination thereof, and a particulate material or a water soluble silicate-containing material that interacts with the compound are described herein. The polyhydroxy aromatic compound can be a water soluble compound having from two to thirty hydroxyl groups. The particulate material can exhibit a particle size distribution, wherein at least about 90% by weight of the particles have a diameter of less than 2 mm. Suitable particulate materials include nanoparticles and microparticles. The cementitious compositions can be used to form building materials. The cementitious compositions are especially suited for inhibiting corrosion of reinforcing steel bars embedded in concrete mixtures. Methods of making and using the cementitious composition are also disclosed.
FILED Thursday, April 18, 2019
APPL NO 16/388000
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/005 (20130101)
C04B 24/02 (20130101)
C04B 24/06 (20130101) Original (OR) Class
C04B 28/04 (20130101)
C04B 28/24 (20130101)
C04B 28/26 (20130101)
C04B 28/188 (20130101)
C04B 40/0046 (20130101)
C04B 2103/22 (20130101)
C04B 2111/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111206 Hoye et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Thomas R. Hoye (St. Paul, Minnesota);  Nicolas Ball-Jones (Minneapolis, Minnesota);  Grant W. Fahnhorst (Minneapolis, Minnesota)
ABSTRACT Monomers, polymers, or oligomers formed therefrom and methods of forming or utilizing monomers of formula I
where R1 is a C1 to C4 alkyl; and X is —OH; —OM where M is lithium (Li), sodium (Na), or potassium (K), NH4+, R5NH3+, R52NH2+, R53NH+, R54N+ where R5 can independently be selected from alkyl, benzyl, and combinations thereof; —OR2 where R2 can be a C1 to C4 alkyl, 2-ethylhexyl, or a hydrocarbon moiety of bio-renewable alcohol or a hydrogenated derivative thereof; —NR3R4, —NR3—NR3R4, —NR3—OR4 where R3 and R4 can independently be H, a C1 to C4 alkyl, or combinations thereof.
FILED Thursday, September 20, 2018
APPL NO 16/136593
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 51/02 (20130101)
C07C 51/02 (20130101)
C07C 51/41 (20130101)
C07C 51/41 (20130101)
C07C 51/60 (20130101)
C07C 51/60 (20130101)
C07C 57/03 (20130101)
C07C 57/03 (20130101)
C07C 57/03 (20130101)
C07C 57/66 (20130101)
C07C 67/08 (20130101)
C07C 67/08 (20130101)
C07C 69/587 (20130101) Original (OR) Class
C07C 69/587 (20130101)
C07C 69/602 (20130101)
C07C 233/09 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/04 (20130101)
C08F 220/06 (20130101)
C08F 236/06 (20130101)
C08F 236/08 (20130101)
C08F 236/10 (20130101)
C08F 236/14 (20130101)
C08F 236/14 (20130101)
C08F 2438/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111343 Kotov et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Nicholas A. Kotov (Ypsilanti, Michigan);  Jian Zhu (Evanston, Illinois);  Siu on Tung (Ann Arbor, Michigan)
ABSTRACT Branched aramid nanofibers (ANFs) can be made by controlled chemical splitting of micro and macroscale aramid fiber by adjusting the reaction media containing aprotic component, protic component and a base. Branched ANFs have uniform size distribution of diameters in the nanoscale regime (below 200 nm) and high yield exceeding 95% of the nanofibers with this diameter. The method affords preparation of branched ANFs with 3-20 branches per one nanofiber and high aspect ratio. Branched ANFs form hydrogel or aerogels with highly porous 3D percolating networks (3DPNs) frameworks that are made into different shapes. Polymers and nanomaterials are impregnated into the 3DPNs through several methods. Gelation of branched ANFs facilitates layer-by-layer deposition in a process described as gelation assisted layer-by-layer deposition (gaLBL). A method of manufacturing battery components including ion conducting membranes, separators, anodes, and cathodes is described. The method of manufacturing of materials with high mechanical performance based on branched ANFs and 3DPNs from them is disclosed.
FILED Thursday, December 29, 2016
APPL NO 16/067498
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics
B29B 13/06 (20130101)
B29B 15/08 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/075 (20130101)
C08J 5/005 (20130101)
C08J 5/18 (20130101)
C08J 5/046 (20130101) Original (OR) Class
C08J 2363/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 9/00 (20130101)

Compositions of Macromolecular Compounds
C08L 63/00 (20130101)
C08L 63/00 (20130101)
C08L 77/06 (20130101)
C08L 77/10 (20130101)
C08L 77/10 (20130101)
C08L 2203/20 (20130101)
C08L 2205/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111364 Deans et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Taneisha Deans (Cleveland, Ohio);  David Schiraldi (Shaker Heights, Ohio)
ABSTRACT A polymer composite material includes a blend of one or more thermoplastic polymers and one or more bio-based flame retardant additives, wherein the one or more bio-based flame retardant additives are present in an amount of 35 to 100 parts per 100 parts by weight of the one or more thermo-plastic polymers. A method of forming the polymer composite material includes: blending the one or more thermoplastic polymers and the one or more bio-based flame retardant additives together at a temperature between 140° C. and 230° C. to form the polymer composite material; forming an article from the polymer composite material; and cooling the formed article.
FILED Friday, March 10, 2017
APPL NO 16/083880
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compounds of Unknown Constitution
C07G 1/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 3/346 (20130101)
C08K 5/06 (20130101)
C08K 5/0066 (20130101)
C08K 5/092 (20130101)
C08K 5/134 (20130101)
C08K 5/1545 (20130101)
C08K 5/1545 (20130101)
C08K 5/1545 (20130101)
C08K 2003/2227 (20130101)

Compositions of Macromolecular Compounds
C08L 23/06 (20130101) Original (OR) Class
C08L 23/06 (20130101)
C08L 23/12 (20130101)
C08L 23/0815 (20130101)
C08L 23/0815 (20130101)
C08L 23/0815 (20130101)
C08L 25/06 (20130101)
C08L 27/18 (20130101)
C08L 51/06 (20130101)
C08L 51/06 (20130101)
C08L 51/06 (20130101)
C08L 55/02 (20130101)
C08L 83/04 (20130101)
C08L 89/06 (20130101)
C08L 89/06 (20130101)
C08L 89/06 (20130101)
C08L 97/005 (20130101)
C08L 2201/02 (20130101)
C08L 2207/066 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 21/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111479 Yang
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Shengyuan Yang (West Melbourne, Florida)
ASSIGNEE(S)
INVENTOR(S) Shengyuan Yang (West Melbourne, Florida)
ABSTRACT The present disclosure provides methods, and related kits, for directing cell attachment and spreading on a substrate and inducing isotropic spreading of cells; provides methods, and related kits, for cell sorting; and further provides methods, and related kits, for guided induction of stem cell differentiation.
FILED Tuesday, July 18, 2017
APPL NO 15/652938
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0653 (20130101) Original (OR) Class
C12N 5/0654 (20130101)
C12N 5/0663 (20130101)
C12N 2506/1384 (20130101)
C12N 2513/00 (20130101)
C12N 2531/00 (20130101)
C12N 2533/12 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111497 Sayre
FUNDED BY
Department of Energy (DOE)
Basic Energy Sciences (BES)
Energy Frontier Research Centers (EFRC)
Center for Advanced Biofuel Systems (CABS)
Photosynthetic Antenna Research Center (PARC)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Emerging Frontiers (EF)
APPLICANT(S) NMC, INC. (Los Alamos, New Mexico)
ASSIGNEE(S) NMC, INC. (Los Alamos, New Mexico)
INVENTOR(S) Richard Thomas Sayre (Los Alamos, New Mexico)
ABSTRACT Embodiments of the present invention provide for a transgenic plan, methods of making and DNA constructs for use in the transgenic plant which transgenic plant is capable of modulating its photosynthetic antenna complex composition in response to increases or decreases in light intensity by modulation of the ratio of chlorophyll a to chlorophyll b such that there is an increase in the Chl a/b ratio at high light intensity and a decrease in the Chl a/b ratio at low light intensity versus wild-type plants grown in the same conditions.
FILED Monday, August 17, 2020
APPL NO 16/995499
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0073 (20130101)
C12N 15/825 (20130101)
C12N 15/8222 (20130101)
C12N 15/8237 (20130101) Original (OR) Class
C12N 15/8245 (20130101)
C12N 15/8261 (20130101)
C12N 15/8269 (20130101)

Enzymes
C12Y 114/13122 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111519 Abate et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam R. Abate (San Francisco, California);  John R. Haliburton (San Francisco, California);  Freeman Lan (San Francisco, California);  Adam R. Sciambi (San Francisco, California)
ABSTRACT Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, e.g., via nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet-based methods of preparing nucleic acid barcodes for use in various barcoding applications. The methods described herein facilitate high-throughput sequencing of nucleic acid target molecules as well as single cell and single virus genomic, transcriptomic, and/or proteomic analysis/profiling. Systems and devices for practicing the subject methods are also provided.
FILED Wednesday, February 03, 2016
APPL NO 15/015015
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 1/00 (20130101)
B01F 5/0655 (20130101)
B01F 13/0071 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101)
B01L 7/52 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/021 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0424 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6804 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6874 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/159 (20130101)
C12Q 2563/179 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111591 Nulwala et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) LumiShield Technologies Incorporated (Pittsburgh, Pennsylvania)
ASSIGNEE(S) LUMISHIELD TECHNOLOGIES INCORPORATED (Pittsburgh, Pennsylvania)
INVENTOR(S) Hunaid B. Nulwala (Pittsburgh, Pennsylvania);  John D. Watkins (Pittsburgh, Pennsylvania)
ABSTRACT Methods and compositions for electrodepositing mixed metal reactive metal layers by combining reactive metal complexes with electron withdrawing agents are provided. Modifying the ratio of one reactive metal complex to the other and varying the current density can be used to vary the morphology the metal layer on the substrate.
FILED Friday, June 01, 2018
APPL NO 15/995220
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/44 (20130101) Original (OR) Class
C25D 3/54 (20130101)
C25D 3/56 (20130101)
C25D 5/10 (20130101)
C25D 9/08 (20130101)
C25D 9/10 (20130101)
C25D 9/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111606 Baer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Eric Baer (Cleveland Heights, Ohio);  Jia Wang (Shaker Heights, Ohio);  Deepak Langhe (Cleveland, Ohio)
ABSTRACT A multilayered polymer composite film includes a first polymer material forming a polymer matrix and a second polymer material coextruded with the first polymer material. The second polymer material forms a plurality of fibers embedded within the polymer matrix. The fibers have a rectangular cross-section.
FILED Tuesday, September 18, 2018
APPL NO 16/134581
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 48/08 (20190201)
B29C 48/12 (20190201)
B29C 48/18 (20190201)
B29C 48/154 (20190201)
B29C 48/307 (20190201)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/12 (20130101)
B32B 27/08 (20130101)
B32B 27/20 (20130101)
B32B 27/34 (20130101)
B32B 27/36 (20130101)
B32B 27/302 (20130101)
B32B 2250/02 (20130101)
B32B 2250/03 (20130101)
B32B 2250/24 (20130101)
B32B 2250/40 (20130101)
B32B 2262/02 (20130101)
B32B 2262/0276 (20130101)
B32B 2307/54 (20130101)
B32B 2307/514 (20130101)
B32B 2367/00 (20130101)
B32B 2371/00 (20130101)
B32B 2535/00 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/42 (20130101) Original (OR) Class
D01D 5/253 (20130101)
D01D 5/423 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 6/66 (20130101)
D01F 8/00 (20130101)

Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads
D02G 3/22 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2331/06 (20130101)
D10B 2509/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2973 (20150115)
Y10T 428/24752 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112305 Jarrahi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Research Office (ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Space and Naval Warfare Systems (SPAWAR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Mona Jarrahi (Los Angeles, California);  Christopher W. Berry (Mountain View, California);  Ning Wang (Mountain View, California)
ABSTRACT A photoconductive device that includes a semiconductor substrate, an antenna assembly, and a photoconductive assembly with one or more plasmonic contact electrodes. The photoconductive assembly can be provided with plasmonic contact electrodes that are arranged on the semiconductor substrate in a manner that improves the quantum efficiency of the photoconductive device by plasmonically enhancing the pump absorption into the photo-absorbing regions of semiconductor substrate. In one exemplary embodiment, the photoconductive device is arranged as a photoconductive source and is pumped at telecom pump wavelengths (e.g., 1.0-1.6 μm) and produces milliwatt-range power levels in the terahertz (THz) frequency range.
FILED Tuesday, October 24, 2017
APPL NO 15/792575
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/108 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/09 (20130101)
H01L 31/0224 (20130101)
H01L 31/02327 (20130101)
H01L 31/035209 (20130101)
H01L 33/04 (20130101)
H01L 33/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112309 Akkus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Ozan Akkus (Cleveland Heights, Ohio);  Haithem A. B. Mustafa (Shaker Heights, Ohio)
ABSTRACT An imaging system that includes a digital micromirror device (DMD) and a tunable filter, wherein the imagining system applicable for Raman imaging, can fluorescent imaging, phosphorescent imaging, photoluminescent imaging, all of which require excitation of a specimen at a particular wavelength and analyzing the reflected light from the specimen at a wavelength that is different from the excitation wavelength, so called inelastic light scattering—ILS. A reconfigurable DMD-based inverse, spatially offset Raman spectroscopy (SORS) system is also described. Beneficially, the DMD system in the excitation path provides a uniform intensity over the sample field of view. It is also configured to prevent sample damage. Placement of a second DMD in the return path of light enables selective rejection of light in space to obtain a reconfigurable inverse SORS system that enables collection of information from different layer depths of the sample using a single detector.
FILED Friday, October 05, 2018
APPL NO 16/754040
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/021 (20130101)
G01J 3/44 (20130101) Original (OR) Class
G01J 2003/1221 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101)
G01N 21/6456 (20130101)

Optical Elements, Systems, or Apparatus
G02B 26/0833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113344 Lu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Yung-hsiang Lu (West Lafayette, Indiana);  Ryan Merrill Dailey (McLean, Virginia)
ABSTRACT A method for indexing network camera data across heterogeneous web page structures is disclosed, which includes receiving a list of predetermined file formats, generating a list of IP network camera IP addresses, sending requests to each of the IP addresses, including transmitting a HTTP request to each IP address in the list, based on a response or lack thereof determine if an IP address is i) a network camera thereby adding the IP address to a list of network cameras, ii) a website thereby adding the IP address to a list of websites to be further investigated, or iii) an address void of network camera information thereby skipping the IP address, and crawling the IP addresses that have been determined to be websites using a web crawler identifying IP addresses of network cameras and resource path associated therewith and adding the same to the list of network cameras.
FILED Sunday, April 12, 2020
APPL NO 16/846365
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 16/951 (20190101) Original (OR) Class
G06F 16/958 (20190101)
G06F 16/9566 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 61/1511 (20130101)
H04L 67/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113553 Reda et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Brown University (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Sherief Reda (Providence, Rhode Island);  Hokchhay Tann (Providence, Rhode Island);  Heng Zhao (Mansfield, Massachusetts)
ABSTRACT A method of accelerated iris recognition includes acquiring an image comprising at least an iris and a pupil, segmenting the iris and the pupil using a fully convolutional network (FCN) model, normalizing the segmented iris, encoding the normalized iris, the normalizing and encoding using a rubber sheet model and 1-D log Gabor filter, and masking the encoded iris.
FILED Friday, November 15, 2019
APPL NO 16/685690
ART UNIT 2652 — Videophones and Telephonic Communications
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0061 (20130101)
G06K 9/00617 (20130101)
G06K 9/00979 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113622 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) University of Oregon (Eugene, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon)
INVENTOR(S) Hailin Wang (Eugene, Oregon);  Mark C. Kuzyk (Eugene, Oregon)
ABSTRACT Spin qubits are situated in mechanical resonators that are acoustically coupled with acoustic waveguides. The acoustic waveguides provide frequency dependent phonon propagation selected so that mechanical resonators adjacent to a selected mechanical resonator are acoustically coupled to the selected mechanical resonator in different acoustic frequency ranges. This configure permits directional transfer of quantum states between spins in spin-mechanical resonator and provides a scalable platform for spin-based quantum computing.
FILED Tuesday, March 05, 2019
APPL NO 16/293555
ART UNIT 2843 — AI & Simulation/Modeling
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 3/0029 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114161 Kan'an et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Nadim H. Kan'an (Mansfield Center, Connecticut);  Ali Gokirmak (Mansfield Center, Connecticut);  Helena Silva (Mansfield Center, Connecticut)
ABSTRACT A reconfigurable phase change device with methods for operating and forming the same are disclosed. An example device can comprise a reconfigurable layer comprising a phase change material, and a set of contacts connected with the reconfigurable layer. The set of contacts can comprise at least a first contact, a second contact, and a third contact. The device can comprise at least one control element electrically coupled with one or more of the set of contacts. The at least one control element can be configured to supply a first control signal to one or more of the set of contacts. The first control signal can be configured to modify a first portion of the reconfigurable layer thereby isolating the first contact from the second contact and the third contact.
FILED Monday, September 24, 2018
APPL NO 16/140351
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/003 (20130101)
G11C 13/0004 (20130101)
G11C 13/0069 (20130101) Original (OR) Class
G11C 13/0097 (20130101)
G11C 2013/009 (20130101)
G11C 2213/52 (20130101)
G11C 2213/53 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/2463 (20130101)
H01L 45/06 (20130101)
H01L 45/144 (20130101)
H01L 45/1206 (20130101)
H01L 45/1233 (20130101)
H01L 45/1253 (20130101)
H01L 45/1608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114623 Lunt, III et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Richard R. Lunt, III (Williamston, Michigan);  John Suddard-Bangsund (Monticello, Minnesota);  Christopher Traverse (Haslett, Michigan);  Margaret Young (Troy, Michigan)
ABSTRACT Photo-active devices including a substrate, a first electrode, an active layer including an organic salt or salt mixture that selectively or predominantly harvests light from the near infrared or infrared regions of the solar spectrum, and a second electrode. The devices are either visibly transparent or visibly opaque and can be utilized in single- or multi-junction devices.
FILED Tuesday, October 24, 2017
APPL NO 15/791949
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 23/166 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/002 (20130101)
H01L 51/006 (20130101)
H01L 51/008 (20130101)
H01L 51/0046 (20130101)
H01L 51/0064 (20130101) Original (OR) Class
H01L 51/424 (20130101)
H01L 51/4246 (20130101)
H01L 2251/308 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114663 Dai et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
National Science Foundation (NSF)
APPLICANT(S) Apple Inc. (Cupertino, California)
ASSIGNEE(S) Apple Inc. (Cupertino, California)
INVENTOR(S) Hongli Dai (Los Altos, California);  Huiming Wu (San Jose, California);  Dapeng Wang (San Jose, California)
ABSTRACT Mixed-metal oxides and lithiated mixed-metal oxides are disclosed that involve compounds according to, respectively, NixMnyCozMeαOβ and Li1+γNixMnyCozMeαOβ. In these compounds, Me is selected from B, Na, Mg, Al, Si, K, Ca, Sc, Ti, V, Cr, Fe, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Ru, Ag, In, and combinations thereof; 0≤x≤1; 0≤y≤1; 0≤z<1; x+y+z>0; 0≤α≤0.5; and x+y+α>0. For the mixed-metal oxides, 1≤β≤5. For the lithiated mixed-metal oxides, −0.1≤γ≤1.0 and 1.9≤β≤3. The mixed-metal oxides and the lithiated mixed-metal oxides include particles having an average density greater than or equal to 90% of an ideal crystalline density.
FILED Wednesday, February 26, 2020
APPL NO 16/802162
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 15/02 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 45/006 (20130101)
C01G 51/00 (20130101)
C01G 51/04 (20130101)
C01G 51/006 (20130101)
C01G 51/50 (20130101)
C01G 51/66 (20130101)
C01G 53/006 (20130101)
C01G 53/50 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/76 (20130101)
C01P 2002/77 (20130101)
C01P 2004/03 (20130101)
C01P 2004/51 (20130101)
C01P 2004/61 (20130101)
C01P 2006/10 (20130101)
C01P 2006/11 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20075 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101) Original (OR) Class
H01M 4/525 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
H01M 50/20 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114671 Xia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Younan Xia (Atlanta, Georgia);  Shuifen Xie (Fujian, China PRC);  Sang-Il Choi (Atlanta, Georgia);  Xue Wang (Atlanta, Georgia);  Jinho Park (Atlanta, Georgia);  Lei Zhang (Xiamen, China PRC)
ABSTRACT Core-shell nanostructures with platinum overlayers conformally coating palladium nano-substrate cores and facile solution-based methods for the preparation of such core-shell nanostructures are described herein. The obtained Pd@Pt core-shell nanocatalysts showed enhanced specific and mass activities towards oxygen reduction, compared to a commercial Pt/C catalyst.
FILED Tuesday, March 17, 2015
APPL NO 14/659879
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/42 (20130101)
B01J 23/44 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/005 (20130101)
C30B 7/14 (20130101)
C30B 29/02 (20130101)
C30B 29/60 (20130101)
C30B 29/66 (20130101)
C30B 29/607 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8657 (20130101) Original (OR) Class
H01M 2008/1095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114951 Reitz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) C-Motive Technologies, Inc. (Madison, Wisconsin)
ASSIGNEE(S) C-Motive Technologies Inc. (Madison, Wisconsin)
INVENTOR(S) Graham T. Reitz (Madison, Wisconsin);  William D. Butrymowicz (Madison, Wisconsin);  Justin K Reed (Madison, Wisconsin);  Daniel C. Ludois (Middleton, Wisconsin)
ABSTRACT An electrostatic machine includes a drive electrode and a stator electrode. The drive electrode and the stator electrode are separated by a gap and form a capacitor. The drive electrode is configured to move with respect to the stator electrode. The electrostatic machine further includes a housing configured to enclose the drive electrode and the stator electrode. The stator electrode is fixed to the housing. The electrostatic machine also includes a dielectric fluid that fills a void defined by the housing, the drive electrode, and the stator electrode. The dielectric fluid includes an ester.
FILED Tuesday, November 07, 2017
APPL NO 16/347975
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/095 (20130101)

Dynamo-electric Machines
H02K 5/04 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/002 (20130101) Original (OR) Class
H02N 1/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115475 Melodia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT Implantable and wearable devices and system for transmitting signals ultrasonically through biological tissue are implemented based on an Internet of Medical Things (IoMT) platform software and hardware architecture. The devices are size-, energy-, and resource-constrained and implement ultrasonic communication protocols and communicate with each other through ultrasound.
FILED Thursday, August 17, 2017
APPL NO 15/679717
ART UNIT 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/08 (20130101)
A61B 5/0015 (20130101)
A61B 5/0022 (20130101)
A61B 5/024 (20130101)
A61B 5/0028 (20130101)
A61B 5/0031 (20130101)
A61B 5/0077 (20130101)
A61B 5/0215 (20130101)
A61B 5/283 (20210101)
A61B 5/291 (20210101)
A61B 5/389 (20210101)
A61B 5/4806 (20130101)
A61B 5/4845 (20130101)
A61B 5/6846 (20130101)
A61B 5/14532 (20130101)
A61B 5/14539 (20130101)
A61B 5/14542 (20130101)
A61B 5/14546 (20130101)
A61B 2562/0219 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/67 (20180101)

Transmission
H04B 1/385 (20130101)
H04B 11/00 (20130101)
H04B 13/005 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 61/6059 (20130101)
H04L 67/12 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 4/38 (20180201)
H04W 4/70 (20180201)
H04W 4/80 (20180201)
H04W 52/0209 (20130101)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 30/70 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11109869 Boyle et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Texas A and M University System (College Station, Texas)
INVENTOR(S) Anthony Boyle (College Station, Texas);  Keith Hearon (Augusta, Georgia);  Duncan J. Maitland (College Station, Texas);  Landon D. Nash (College Station, Texas);  Thomas S. Wilson (San Leandro, California)
ABSTRACT An embodiment of the invention is a shape memory polymer (SMP) foam designed to recover its original shape through exposure to a solvent. Thermo-responsive SMPs are polymers designed to maintain a programmed secondary shape until heated above their transition temperature, upon which the polymer recovers its original, or primary, shape. The thermo-responsive SMP foam is programmed to its secondary shape prior to use, typically compression of the foam to a small volume, and remains in this programmed shape until exposed to a selected solvent such as dimethyl sulfoxide or ethyl alcohol. Upon exposure to the solvent, the transition temperature of the SMP foam decreases below the temperature of the environment and the SMP foam actuates to its primary shape. The SMP foam is tailored to actuate upon exposure to specific solvents while minimizing or preventing actuation when exposed to water or other solvents. This selective solvent actuation can be used to increase working time of a SMP foam device, that is, the time allowed for use of a device without undesired actuation, while maintaining functional SMP actuation. Solvent actuated SMP foams can be used in various applications including, but not limited to, treatment of aneurysms and arterio-venous malformations, tissue engineering, and wound healing.
FILED Thursday, January 30, 2020
APPL NO 16/776638
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1219 (20130101)
A61B 17/12031 (20130101)
A61B 17/12113 (20130101)
A61B 17/12181 (20130101) Original (OR) Class
A61B 2017/00871 (20130101)
A61B 2017/00938 (20130101)
A61B 2017/00964 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/06 (20130101)
A61L 31/06 (20130101)
A61L 31/14 (20130101)
A61L 31/146 (20130101)
A61L 2400/16 (20130101)
A61L 2430/36 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110405 Long et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeffrey R. Long (Oakland, California);  Jonathan Bachman (Berkeley, California);  Zachary Pace Smith (Belmont, Massachusetts)
ABSTRACT The disclosure provides for polymer membranes which comprise metal organic frameworks, methods of making therein, and methods of use thereof, including in gas separation.
FILED Tuesday, November 15, 2016
APPL NO 15/775376
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 53/04 (20130101)
B01D 53/62 (20130101)
B01D 53/228 (20130101)
B01D 67/0079 (20130101)
B01D 69/02 (20130101)
B01D 69/12 (20130101)
B01D 69/148 (20130101) Original (OR) Class
B01D 71/64 (20130101)
B01D 2253/204 (20130101)
B01D 2256/10 (20130101)
B01D 2256/16 (20130101)
B01D 2256/22 (20130101)
B01D 2256/24 (20130101)
B01D 2256/245 (20130101)
B01D 2257/102 (20130101)
B01D 2257/108 (20130101)
B01D 2257/504 (20130101)
B01D 2257/702 (20130101)
B01D 2257/7022 (20130101)
B01D 2257/7025 (20130101)
B01D 2325/02 (20130101)
B01D 2325/30 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)
B01J 20/28026 (20130101)
B01J 20/28033 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/20 (20130101)
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110493 Tombs et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Eastman Kodak Company (Rochester, New York)
ASSIGNEE(S) Eastman Kodak Company (Rochester, New York)
INVENTOR(S) Thomas Nathaniel Tombs (Rochester, New York);  Todd Mathew Spath (Hilton, New York);  Douglas Edward Garman (Webster, New York);  Carolyn Rae Ellinger (Rochester, New York);  Christopher B. Liston (Rochester, New York)
ABSTRACT An electrode film includes a first electrode pattern having a first set of parallel conductive electrodes and a second electrode pattern having a second set of parallel conductive electrodes disposed on a first surface of a transparent film, wherein elements of the first electrode pattern do not cross over elements of the second electrode pattern. A third electrode pattern having a third set of parallel conductive electrodes is disposed on a second surface of the transparent film, wherein the first, second and third sets of parallel conductive electrodes are arranged in an interlaced pattern. The electrode patterns are configured to be connected to respective power sources of electrical power supplying respective waveforms to generate a time-varying electric field pattern above a surface of the electrode film.
FILED Tuesday, August 21, 2018
APPL NO 16/106051
ART UNIT 2871 — Optics
CURRENT CPC
Domestic Washing or Cleaning; Suction Cleaners in General
A47L 1/02 (20130101)

Cleaning in General; Prevention of Fouling in General
B08B 6/00 (20130101) Original (OR) Class

Solar Heat Collectors; Solar Heat Systems
F24S 40/20 (20180501)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/10 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110681 Cockeram
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Naval Nuclear Laboratory (NNL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Brian V. Cockeram (West Mifflin, Pennsylvania)
ABSTRACT Disclosed is a hermetic bond for a joint including a first layer of silicon carbide; a second layer of silicon carbide; and a bonding layer positioned between the first layer and the second layer, wherein the bonding layer includes an iridium layer, a first reaction zone positioned between the iridium foil layer and the first layer, and a second reaction zone positioned between the iridium foil layer and the second layer, wherein the first reaction zone and the second reaction zone include iridium silicides.
FILED Thursday, June 27, 2019
APPL NO 16/454240
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/0008 (20130101)
B23K 2101/04 (20180801)
B23K 2103/52 (20180801)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 1/08 (20130101) Original (OR) Class
B32B 15/04 (20130101)
B32B 37/10 (20130101)
B32B 2309/02 (20130101)
B32B 2309/04 (20130101)
B32B 2309/12 (20130101)
B32B 2309/68 (20130101)
B32B 2309/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110682 Qiao et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Yu Qiao (San Diego, California);  Ying Zhong (San Diego, California)
ABSTRACT A multilayer structure comprising solid layers and defining at least one gap that separates the solid layers to form an alternating pattern of the solid layers and the at least one gap in the structure.
FILED Monday, May 15, 2017
APPL NO 16/300492
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/08 (20130101) Original (OR) Class
B32B 3/10 (20130101)
B32B 7/02 (20130101)
B32B 7/05 (20190101)
B32B 9/005 (20130101)
B32B 9/007 (20130101)
B32B 9/041 (20130101)
B32B 9/043 (20130101)
B32B 9/045 (20130101)
B32B 9/047 (20130101)
B32B 15/06 (20130101)
B32B 15/09 (20130101)
B32B 15/14 (20130101)
B32B 15/082 (20130101)
B32B 15/085 (20130101)
B32B 15/088 (20130101)
B32B 15/095 (20130101)
B32B 17/10 (20130101)
B32B 23/08 (20130101)
B32B 23/20 (20130101)
B32B 23/042 (20130101)
B32B 23/046 (20130101)
B32B 25/08 (20130101)
B32B 25/10 (20130101)
B32B 25/16 (20130101)
B32B 25/18 (20130101)
B32B 25/20 (20130101)
B32B 27/12 (20130101)
B32B 27/32 (20130101)
B32B 27/34 (20130101)
B32B 27/36 (20130101)
B32B 27/40 (20130101)
B32B 27/281 (20130101)
B32B 27/283 (20130101)
B32B 27/288 (20130101)
B32B 27/302 (20130101)
B32B 27/304 (20130101)
B32B 27/306 (20130101)
B32B 27/308 (20130101)
B32B 27/322 (20130101)
B32B 27/365 (20130101)
B32B 37/18 (20130101)
B32B 2250/02 (20130101)
B32B 2255/06 (20130101)
B32B 2255/10 (20130101)
B32B 2255/20 (20130101)
B32B 2255/26 (20130101)
B32B 2255/205 (20130101)
B32B 2260/021 (20130101)
B32B 2262/101 (20130101)
B32B 2262/106 (20130101)
B32B 2266/122 (20161101)
B32B 2266/126 (20161101)
B32B 2307/73 (20130101)
B32B 2307/102 (20130101)
B32B 2307/206 (20130101)
B32B 2307/208 (20130101)
B32B 2307/412 (20130101)
B32B 2307/414 (20130101)
B32B 2307/728 (20130101)
B32B 2419/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111142 Marker et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Gas Technology Institute (Des Plaines, Illinois)
ASSIGNEE(S) Gas Technology Institute (Des Plaines, Illinois)
INVENTOR(S) Terry Marker (Palos Heights, Illinois);  Jim Wangerow (Oak Park, Illinois);  Pedro Ortiz-Toral (Wheeling, Illinois);  Martin Linck (Roscoe, Illinois)
ABSTRACT Processes and catalysts for producing hydrogen by reforming methane are disclosed, which afford considerable flexibility in terms of the quality of the reformer feed. This can be attributed to the robustness of the noble metal-containing catalysts described herein for use in reforming, such that a number of components commonly present in methane-containing process streams can advantageously be maintained without conventional upgrading (pretreating) steps, thereby improving process economics. This also allows for the reforming of impure reformer feeds, even in relatively small quantities, which may be characterized as complex gas mixtures due to significant quantities of non-methane components. A representative reforming catalyst comprises 1 wt-% Pt and 1 wt-% Rh as noble metals, on a cerium oxide support.
FILED Tuesday, September 18, 2018
APPL NO 16/134623
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/40 (20130101) Original (OR) Class
C01B 2203/107 (20130101)
C01B 2203/0233 (20130101)
C01B 2203/0238 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111199 Parkin et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOEOS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Gerard Parkin (New York, New York);  Zack Strater (New York, New York);  Michael Rauch (Short Hills, New Jersey)
ABSTRACT The present disclosure provides, inter alia, methods for preparing formaldehyde from carbon dioxide using bis(silyl)acetals, methods for incorporating carbon derived from carbon dioxide into a complex organic molecule derived from formaldehyde using bis(silyl)acetals, and methods for generating an isotopologue of a complex organic molecule derived from formaldehyde using bis(silyl)acetals.
FILED Friday, March 27, 2020
APPL NO 16/833483
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/146 (20130101)
B01J 31/1815 (20130101)
B01J 2531/22 (20130101)

Acyclic or Carbocyclic Compounds
C07C 45/515 (20130101) Original (OR) Class
C07C 47/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111330 Guan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Zhibin Guan (Irvine, California);  Aaron M. Kushner (Solana Beach, California)
ABSTRACT A self-healing polymer material that includes a multiphase copolymer, and a method of making the copolymer, are provided. The multiphase copolymer includes one or more hydrogen bond-forming copolymer segments, each segment including a polymerized acrylamide monomer and a polymerized acrylic monomer. The polymerized acrylamide monomer includes functional groups that form hydrogen bonds in the multiphase copolymer, and is present in the one or more copolymer segments in an amount sufficient for self-healing of the multiphase copolymer.
FILED Monday, June 20, 2016
APPL NO 15/736210
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/34 (20130101)
C08F 12/18 (20130101)
C08F 212/08 (20130101)
C08F 212/14 (20130101)
C08F 220/18 (20130101)
C08F 220/56 (20130101)
C08F 220/1804 (20200201)
C08F 257/02 (20130101)
C08F 257/02 (20130101)
C08F 293/005 (20130101) Original (OR) Class
C08F 2438/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111359 Kunc et al.
FUNDED BY
Department of Energy (DOE)
UT-Battelle, LLC (UT-BATTELLE)
Oak Ridge National Laboratory (ORNL)
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Vlastimil Kunc (Oak Ridge, Tennessee);  John M. Lindahl (Knoxville, Tennessee);  Lonnie J. Love (Oak Ridge, Tennessee);  Brian K. Post (Oak Ridge, Tennessee);  Ahmed Hassen (Oak Ridge, Tennessee);  Peng Liu (Oak Ridge, Tennessee);  Thomas Zeke Sudbury (Oak Ridge, Tennessee)
ABSTRACT A method of forming a low-density three-dimensional article is provided. The method includes printing a low-density composition on a substrate to form at least one layer comprising the low-density composition. The low-density composition includes a (P) polymer component and (M) a microsphere component in a ratio by volume (P):(M). The method also includes selectively controlling a density of the low-density composition during printing to give the at least one layer on the substrate. Selectively controlling the density of the low-density composition includes varying the ratio (P):(M) during printing. The method further includes repeating the printing and selectively controlling the density of the low-density composition to form additional layer(s), thereby forming the low-density three-dimensional article. A low-density three-dimensional article prepared in accordance with the method is also provided.
FILED Monday, May 06, 2019
APPL NO 16/403995
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/165 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2055/02 (20130101)
B29K 2077/00 (20130101)
B29K 2105/16 (20130101)
B29K 2105/165 (20130101)
B29K 2507/04 (20130101)
B29K 2509/08 (20130101)
B29K 2995/0063 (20130101)
B29K 2995/0064 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/201 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 7/06 (20130101)
C08K 7/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111468 Knipe et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
Lawrence Livermore National Security LLC (LLNS)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Laboratory, LLC (Livermore, California)
INVENTOR(S) Jennifer Marie Knipe (Oakland, California);  Sarah E. Baker (Dublin, California);  Marcus A. Worsley (Hayward, California);  Swetha Chandrasekaran (Dublin, California)
ABSTRACT Generation of energy and storage of energy for subsequent use is provided by electromethanogenesis of carbon dioxide into a fuel gas and the storage of the fuel gas for subsequent use. An electromethanogenic reactor includes an anode conductor and a cathode conductor wherein the cathode conductor includes submicron to micron scale pores. Electromethanogenesis microbes and/or enzymes are located in the micron scale pores of the cathode electrode conductor. Carbon dioxide is introduced into the electromethanogenic reactor and the electromethanogenesis microbes/enzymes and the carbon dioxide interact and produce a fuel gas. The fuel gas is stored for subsequent use, for example use in power generation.
FILED Tuesday, April 10, 2018
APPL NO 15/949378
ART UNIT 1799 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/04 (20130101) Original (OR) Class
C12M 23/34 (20130101)
C12M 35/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111497 Sayre
FUNDED BY
Department of Energy (DOE)
Basic Energy Sciences (BES)
Energy Frontier Research Centers (EFRC)
Center for Advanced Biofuel Systems (CABS)
Photosynthetic Antenna Research Center (PARC)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOEOS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Emerging Frontiers (EF)
APPLICANT(S) NMC, INC. (Los Alamos, New Mexico)
ASSIGNEE(S) NMC, INC. (Los Alamos, New Mexico)
INVENTOR(S) Richard Thomas Sayre (Los Alamos, New Mexico)
ABSTRACT Embodiments of the present invention provide for a transgenic plan, methods of making and DNA constructs for use in the transgenic plant which transgenic plant is capable of modulating its photosynthetic antenna complex composition in response to increases or decreases in light intensity by modulation of the ratio of chlorophyll a to chlorophyll b such that there is an increase in the Chl a/b ratio at high light intensity and a decrease in the Chl a/b ratio at low light intensity versus wild-type plants grown in the same conditions.
FILED Monday, August 17, 2020
APPL NO 16/995499
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0073 (20130101)
C12N 15/825 (20130101)
C12N 15/8222 (20130101)
C12N 15/8237 (20130101) Original (OR) Class
C12N 15/8245 (20130101)
C12N 15/8261 (20130101)
C12N 15/8269 (20130101)

Enzymes
C12Y 114/13122 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111578 Elam et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Jeffrey W. Elam (Elmhurst, Illinois);  Anil U. Mane (Naperville, Illinois);  Maximillian Gebhard (Westmont, Illinois)
ABSTRACT A secondary electron emissive coating. The coating is formed by atomic layer deposition of CaF2 on a substrate by ALD half cycle exposure of an alkaline metal amidinate and ALD half cycle exposure of a fluorinated compound, where the deposition occurs at a reaction temperature greater than a highest sublimation temperature of the first metal precursor and the second metal precursor and less than 50° C. above the highest sublimation temperature.
FILED Thursday, February 13, 2020
APPL NO 16/790559
ART UNIT 2881 — Optics
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/30 (20130101) Original (OR) Class
C23C 16/4408 (20130101)
C23C 16/45527 (20130101)
C23C 16/45553 (20130101)
C23C 16/45555 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111590 Hryn et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
UChicago Argonne, LLC (UCHICAGO)
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) John N. Hryn (Naperville, Illinois);  Patricia Anne Ignacio-deLeon (Westmont, Illinois);  Li Tang (Bolingbrook, Illinois);  Daniel Yoav Arenas (Chicago, Illinois)
ABSTRACT System and methods for producing lithium metal from an anodic half-cell and a cathodic half-cell with a lithium permeable membrane therebetween.
FILED Tuesday, September 18, 2018
APPL NO 16/134528
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 1/02 (20130101) Original (OR) Class
C25C 7/02 (20130101)
C25C 7/04 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/0452 (20130101)
H01M 4/1395 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112574 Mathai et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Sagi Varghese Mathai (Sunnyvale, California);  Paul Kessler Rosenberg (Sunnyvale, California);  Georgios Panotopoulos (Berkeley, California)
ABSTRACT Optoelectronic systems with an adapter and methods of manufacturing or assembling the same are provided. An example of an optoelectronic system according to the present disclosure includes a substrate, an interposer, an electronic component disposed on the interposer, and an optical component. The optoelectronic system includes a ferrule and an optical fiber coupled to the ferrule. The optoelectronic system also includes an optical socket configured to receive the ferrule therein. The optoelectronic system further includes an adapter positioned between the interposer and the optical socket. The adapter has a wedge-shaped configuration such that the ferrule is disposed at a non-zero angle relative to the interposer when the ferrule is received in the optical socket and the optical socket is coupled to the adapter.
FILED Thursday, April 30, 2020
APPL NO 16/862979
ART UNIT 2883 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/351 (20130101)
G02B 6/389 (20130101)
G02B 6/4292 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113065 Kalamatianos et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) John Kalamatianos (Boxborough, Massachusetts);  Susumu Mashimo (Fukuoka, Japan);  Krishnan V. Ramani (Santa Clara, California);  Scott Thomas Bingham (Santa Clara, California)
ABSTRACT A technique for speculatively executing load-dependent instructions includes detecting that a memory ordering consistency queue is full for a completed load instruction. The technique also includes storing data loaded by the completed load instruction into a storage location for storing data when the memory ordering consistency queue is full. The technique further includes speculatively executing instructions that are dependent on the completed load instruction. The technique also includes in response to a slot becoming available in the memory ordering consistency queue, replaying the load instruction. The technique further includes in response to receiving loaded data for the replayed load instruction, testing for a data mis-speculation by comparing the loaded data for the replayed load instruction with the data loaded by the completed load instruction that is stored in the storage location.
FILED Thursday, October 31, 2019
APPL NO 16/671097
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3842 (20130101) Original (OR) Class
G06F 9/30043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113388 Urias et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Technology and Engineering Solutions of Sandia, LLC (NTESS)
Sandia National Laboratories (SNL)
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Vincent Urias (Albuquerque, New Mexico);  Caleb Loverro (Albuquerque, New Mexico);  William M.S. Stout (Albuquerque, New Mexico)
ABSTRACT A system, method, and device for cloud forensics and incident response is provided. In an embodiment, a computer-implemented method for performing cloud forensics and incident response includes intercepting, by a cloud incident response module (CIRM), communication between a virtual machine (VM) and a hypervisor. The method also includes extracting, by the CIRM, data from the communication between the VM and the hypervisor according to a forensic policy. Intercepting and extracting the data are transparent to the VM and to the hypervisor. Intercepting and extracting the data are independent of the VM and the hypervisor.
FILED Tuesday, July 31, 2018
APPL NO 16/051005
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 9/542 (20130101)
G06F 9/545 (20130101)
G06F 9/45558 (20130101)
G06F 21/53 (20130101) Original (OR) Class
G06F 2009/45587 (20130101)
G06F 2009/45591 (20130101)
G06F 2009/45595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113594 Ohodnicki et al.
FUNDED BY
Department of Energy (DOE)
National Energy Technology Laboratory (NETL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Paul Ohodnicki (Allison Park, Pennsylvania);  Jagannath Devkota (Pittsburgh, Pennsylvania);  David W Greve (Sedona, Arizona)
ABSTRACT Materials, methods of making, and methods of using an integrated wireless detector for real time interrogating metallic tubular structures comprising: an RF patch antenna; a passive surface acoustic wave (SAW) sensor; and data analytic methodologies. An embodiment relates to interrogating a metallic structure having a uniform cross section using an antenna which launches electromagnetic radiation. A sensor may be located within the structure is configured to re-emit electromagnetic radiation modified depending on parameters for which the sensor has been functionalized. An antenna may receive radiation as modified by the sensor, or may receive the transmitted or backscattered radiation directly, without use of a sensor. The antenna then communicates wirelessly with an interrogator providing data which may be used to understand the operational status of the structure in real-time.
FILED Monday, July 08, 2019
APPL NO 16/504774
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10346 (20130101)
G06K 19/07786 (20130101) Original (OR) Class

Antennas, i.e Radio Aerials
H01Q 1/247 (20130101)
H01Q 9/0407 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114209 Liszkai
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) NuScale Power, LLC (Corvallis, Oregon)
ASSIGNEE(S) NuScale Power, LLC (Corvallis, Oregon)
INVENTOR(S) Tamas Liszkai (Corvallis, Oregon)
ABSTRACT In some embodiments, a nuclear reactor vessel comprises a containment vessel for a reactor pressure vessel (RPV); a control rod drive mechanism (CRDM) located in the containment vessel, the CRDM including drive motors configured to move control rods into and out of a nuclear reactor core located in the RPV; and a partition extending across a portion of the containment vessel configured to retain the drive motors in a separate fluid-tight barrier region within the containment vessel. Other embodiments may be disclosed and/or claimed.
FILED Wednesday, December 19, 2018
APPL NO 16/226298
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 1/32 (20130101)
G21C 7/10 (20130101)
G21C 7/14 (20130101) Original (OR) Class
G21C 13/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114663 Dai et al.
FUNDED BY
Department of Energy (DOE)
Argonne National Laboratory (ANL)
National Science Foundation (NSF)
APPLICANT(S) Apple Inc. (Cupertino, California)
ASSIGNEE(S) Apple Inc. (Cupertino, California)
INVENTOR(S) Hongli Dai (Los Altos, California);  Huiming Wu (San Jose, California);  Dapeng Wang (San Jose, California)
ABSTRACT Mixed-metal oxides and lithiated mixed-metal oxides are disclosed that involve compounds according to, respectively, NixMnyCozMeαOβ and Li1+γNixMnyCozMeαOβ. In these compounds, Me is selected from B, Na, Mg, Al, Si, K, Ca, Sc, Ti, V, Cr, Fe, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Ru, Ag, In, and combinations thereof; 0≤x≤1; 0≤y≤1; 0≤z<1; x+y+z>0; 0≤α≤0.5; and x+y+α>0. For the mixed-metal oxides, 1≤β≤5. For the lithiated mixed-metal oxides, −0.1≤γ≤1.0 and 1.9≤β≤3. The mixed-metal oxides and the lithiated mixed-metal oxides include particles having an average density greater than or equal to 90% of an ideal crystalline density.
FILED Wednesday, February 26, 2020
APPL NO 16/802162
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 15/02 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 45/006 (20130101)
C01G 51/00 (20130101)
C01G 51/04 (20130101)
C01G 51/006 (20130101)
C01G 51/50 (20130101)
C01G 51/66 (20130101)
C01G 53/006 (20130101)
C01G 53/50 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/76 (20130101)
C01P 2002/77 (20130101)
C01P 2004/03 (20130101)
C01P 2004/51 (20130101)
C01P 2004/61 (20130101)
C01P 2006/10 (20130101)
C01P 2006/11 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20075 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101) Original (OR) Class
H01M 4/525 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
H01M 50/20 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114820 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Zhubiao Zhu (Ft. Collins, Colorado);  Clinton Harold Parker (Ft. Collins, Colorado);  Daniel Alan Berkram (Ft. Collins, Colorado)
ABSTRACT A push-pull circuit for an opto-electronic device includes: an output node; a pull-up circuit that, in operation, controls a falling edge rate of an input signal to the opto-electronic device while sharing charge with the output node; and a pull-down circuit that, in operation, controls a rising edge rate of the input signal to the opto-electronic device while sharing charge with the output node.
FILED Monday, November 12, 2018
APPL NO 16/186822
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/1305 (20130101)
H01S 5/183 (20130101)
H01S 5/0428 (20130101) Original (OR) Class

Transmission
H04B 10/508 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 45/32 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114944 Zhang et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Xin Zhang (Chappaqua, New York);  Todd E. Takken (Brewster, New York);  Naigang Wang (Ossining, New York);  Leland Chang (New York, New York)
ABSTRACT A multi-phase buck switching converter having grouped pairs of phases, each phase using two magnetically coupled air-core inductors. For each group, a first driver circuit controlling switching of a first power transistor switching circuit coupled to a first air-core inductor output for driving an output load at the first phase. A second driver circuit controlling switching of a second power transistor switching circuit coupled to a second air-core inductor output for driving said output load at the second phase. The first and second phases are spaced 180° apart. The coupled air-core inductors per group of such orientation, separation distance and mutual inductance polarity relative to each other such that magnetic coupling between the two or more inductors at each phase results in a net increase in effective inductance per unit volume. Each air-core inductor is a metal slab of defined length, height and thickness formed using back-end-of-line semiconductor manufacturing process.
FILED Monday, December 09, 2019
APPL NO 16/707186
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/1584 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115004 Stanley et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
Honeywell Federal Manufacturing and Technologies, LLC (FM&T)
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Dennis L. Stanley (Kansas City, Missouri);  Audrey L. Chritton (Kansas City, Missouri)
ABSTRACT A processing element for implementation in a digital signal processing system is provided. The processing element is configured to receive a first data stream comprising a plurality of digital values where each value represents a sample of an analog signal. The processing element is further configured to receive a second data stream comprising a series of digital values where each value represents a sample of the analog signal. The processing element is configured to filter the first data stream via a first Farrow-structured fractional delay (FD) filter and output a filtered first data stream; filter the second data stream via a second Farrow-structured FD filter and output a filtered second data stream; and temporarily store values from the second data stream and output the stored values to the first Farrow-structured FD filter so that the stored values can be used to filter the first data stream.
FILED Wednesday, August 05, 2020
APPL NO 16/985884
ART UNIT 2849 — Electrical Circuits and Systems
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 17/0018 (20130101) Original (OR) Class
H03H 17/028 (20130101)
H03H 2017/0072 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0029 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115130 Huang et al.
FUNDED BY
Department of Energy (DOE)
Lawrence Livermore National Laboratory (LLNL)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S) Tsung Ching Huang (Palo Alto, California);  Jinsung Youn (Palo Alto, California);  Peter Jin Rhim (Palo Alto, California);  Marco Fiorentino (Palo Alto, California)
ABSTRACT Techniques and circuitry for wavelength monitor and control are disclosed herein. The disclosed wavelength monitor and control circuitry and techniques are designed to realize a multi-channel DWDM optical link by using a photonic receiver that dynamically adjusts resonant wavelengths of the microring drop filter (MDF), as needed. The wavelength monitor and control circuitry can monitor and control the resonant wavelengths of multiple MDFs for a DWDM silicon photonics receiver with minimum power and area overhead. In an embodiment, circuitry for an optical receiver comprises an MDF having resonant wavelength for multiple DWDM channels, and circuitry to control and monitor the resonant wavelength of the MDF in real-time and in manner that compensates for deviation between actual resonant wavelength of the MDF and the incident optical wavelength of the MDF.
FILED Thursday, July 09, 2020
APPL NO 16/925202
ART UNIT 2637 — Optical Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/12 (20130101)
H03M 1/66 (20130101)

Transmission
H04B 10/69 (20130101) Original (OR) Class
H04B 10/07955 (20130101)

Multiplex Communication
H04J 14/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11111980 Myers et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) W. Neill Myers (Huntsville, Alabama);  Robert E. Berry (Madison, Alabama);  Frederick Scott Gant (Huntsville, Alabama);  Jeffrey Lee Lindner (Madison, Alabama);  John S. Townsend (Union Grove, Alabama)
ABSTRACT A unidirectional damping system includes a shaft and unidirectional damping modules. Each module is fixedly coupled to the shaft. Each module includes a fluid-filled variable-volume chamber and spring(s). The chamber has at least one port through which fluid flows based on changes in volume of the chamber wherein, when the shaft is adapted to have a unidirectional force applied thereto, the chamber decreases in volume. The spring(s) is coupled to the chamber for increasing volume of the chamber when the unidirectional force is not applied to the shaft. A fluid-filled spacer chamber is coupled between adjacent modules and is uncoupled from the shaft. The spacer chamber includes at least one venting port through which fluid flows based on pressure in the spacer chamber.
FILED Tuesday, March 30, 2021
APPL NO 17/217823
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 9/0472 (20130101) Original (OR) Class
F16F 15/0232 (20130101)
F16F 2222/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112040 Sparks et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Michael Stephen Sparks (Union Grove, Alabama);  Verbon Blake Sparks (Grant, Alabama)
ABSTRACT A gimbal apparatus is disclosed, including a tubular envelope with a variable length between first and second rim structures. A rigid ring structure inside the tubular envelope is connected to diametrically opposite first and second portions of the first rim structure, and is connected to diametrically opposite first and second portions of the second rim structure. A spoke bisects the ring structure.
FILED Wednesday, August 01, 2018
APPL NO 16/052468
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Jet-propulsion Plants
F02K 9/44 (20130101)

Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 27/02 (20130101)
F16L 27/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11112507 Dill
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Evan T. Dill (Poquoson, Virginia)
ABSTRACT A method may be executed by a base station or mobile device to improve accuracy of a global positioning system (GPS)-based position or “geoposition” of the mobile device. A time-stamped first set of GPS data may be received via a GPS receiver, e.g., of the base station. A second set of GPS data describing a geoposition of the mobile device is received from the mobile device by the base station. A time of collection of the base station and mobile device GPS data coincides. The GPS data includes code phase and pseudo-range data from each of the GPS satellites, and may include carrier phase data. A predetermined GPS position correction technique is used to generate a corrected geoposition of the mobile device using the GPS data. The corrected geoposition is then transmitted to the mobile device and/or an external response system such as a drone or first responder.
FILED Tuesday, August 01, 2017
APPL NO 15/665716
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/04 (20130101)
G01S 19/41 (20130101) Original (OR) Class
G01S 19/43 (20130101)
G01S 19/071 (20190801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113436 Majumdar et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Alok Kumar Majumdar (Huntsville, Alabama);  Paul Alan Schallhorn (Melbourne, Florida);  Andre Christopher LeClair (Huntsville, Alabama)
ABSTRACT A computer-implemented method is provided for simultaneous simulation of one-dimensional flow and multi-dimensional flow in a fluid flow network. Processes define meshes of nodes for both one-dimensional and multi-dimensional flow components in a fluid flow network. Another process defines a relational data structure for each adjacent node pair in each multi-dimensional flow component. A flow analysis code is executed to model fluid flow throughout the fluid flow network using the one-dimensional and multi-dimensional meshes of nodes, and each relational data structure.
FILED Thursday, November 21, 2019
APPL NO 16/691142
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 7/0676 (20130101)

Electric Digital Data Processing
G06F 30/20 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114713 Sunada et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Eric T. Sunada (Alhambra, California);  Scott N. Roberts (Altadena, California);  Benjamin I. Furst (Pasadena, California);  Ratnakumar V. Bugga (Arcadia, California)
ABSTRACT Thermal management systems for battery cells and methods for their additive manufacture are provided. The thermal management systems include at least one heat pipe that physically contacts the battery cell and conforms to its geometry. Each battery cell is deposited within a separate heat pipe, and each heat pipe is disposed on a base plate, which itself connects to a heat sink. In many embodiments, the heat pipe is a two-phase heat exchanger having three major components: liquid channels, wick elements, and vapor channels. In such embodiments, the wick component comprises a porous body configured to be disposed between the liquid channels and vapor channels. The wick component may be made using a stochastic additive manufacturing process such that the wick component may take any configuration and/or such that the wick component may be directly integrated into the body of the heat pipe as a unitary piece thereof. In other embodiments, the heat pipe is a cavity with flow channels in which fluid can be pumped through. In some such embodiments, the fluid can occupy the heat pipe in a one-phase or two-phase state. This unitary heat pipe is part of a monolithic thermal management system.
FILED Thursday, June 20, 2019
APPL NO 16/447824
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/613 (20150401)
H01M 10/653 (20150401)
H01M 10/658 (20150401)
H01M 10/6552 (20150401)
H01M 10/6567 (20150401)
H01M 10/6569 (20150401) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115569 Myers et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Jeremy Dwight Myers (Taft, Tennessee);  Jonathan Eugene Pryor (Madison, Alabama);  Jarret Carl Bone (Madison, Alabama)
ABSTRACT A ruggedized camera system provides high-quality optical data signals while operating in harsh environments and includes a housing having an electronics housing section and a lens housing section. A light-ring circuit is attached to the lens housing section. A diffuser ring is attached to the lens housing section and covers the light-ring circuit. The camera system includes camera electronics that process optical data captured by the camera optical lens. The camera electronics are secured within a camera electronics holder that is located within and attached to the electronic housing section and which minimizes vibrations to the camera electronics. A power circuit is inside and attached to the electronic housing section and provides power to the camera electronics and the light-ring circuit and receives serial command data being transmitted to the camera electronics. The housing tightly integrates the camera optical lens, the camera electronics holder, the light-ring circuit and power circuit.
FILED Thursday, August 20, 2020
APPL NO 16/998837
ART UNIT 2697 — Selective Visual Display Systems
CURRENT CPC
Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 3/10 (20130101)
G03B 17/08 (20130101)

Pictorial Communication, e.g Television
H04N 5/2252 (20130101) Original (OR) Class
H04N 5/2254 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11115573 Fahringer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia);  AUBURN UNIVERSITY (Auburn University, Alabama)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Timothy W. Fahringer (Hampton, Virginia);  William Hutchins (Newport News, Virginia);  Paul M. Danehy (Newport News, Virginia);  Brian S. Thurow (Auburn, Alabama)
ABSTRACT Methods, systems, and apparatuses for a hyperspectral plenoptic camera. A hyperspectral plenoptic camera may be configured with a filter in the aperture plane of the camera. The filter may selectively transmit radiated wavelengths to a microlens array, which may focus and transmit the wavelengths to an image sensor based on, e.g., the location and intensity of the wavelengths. One or more lenses and/or an iris may be configured to collect, focus, and/or transmit wavelengths to and from the filter. The filter may be located between two lenses, and the distance between the two lenses may be based on a diameter of an aperture of the plenoptic camera.
FILED Wednesday, May 15, 2019
APPL NO 16/413231
ART UNIT 2697 — Selective Visual Display Systems
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/20 (20130101)
G02B 27/0961 (20130101)

Pictorial Communication, e.g Television
H04N 5/2253 (20130101)
H04N 5/2254 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11113316 Atkins et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) C. Scot Atkins (Chantilly, Virginia);  Joseph Conway (Annandale, Virginia)
ABSTRACT A method, system, and computer program for processing records is disclosed. In some aspects, a method includes associating, on at least one of the plurality of processors, each record with a record set of a plurality of record sets. Each record set is assigned to a sub-database based on the record set. A cache is associated with each sub-database, and each sub-database and its associated cache is associated with a processor set. An affinity is created between each database cache and the associated processor set, and records are processed with the processor sets according to the associations.
FILED Friday, December 06, 2019
APPL NO 16/705917
ART UNIT 2165 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 9/5033 (20130101)
G06F 16/285 (20190101) Original (OR) Class
G06F 16/24532 (20190101)
G06F 16/24542 (20190101)
G06F 16/24552 (20190101)
G06F 2209/5012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113658 Aryeetey et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Nii-Kwashie Aryeetey (Washington, District of Columbia);  Robert E. Dixon, Jr. (Washington, District of Columbia);  Naomi Miller (Washington, District of Columbia)
ABSTRACT Systems and methods for generating and implementing a household customer database are disclosed. In one aspect, a method for processing items comprises receiving a first item to be delivered and identifying data corresponding to one or more of a source information and destination information of the first item. The method further comprises identifying secondary information of the first item, storing the source, destination, and secondary information in a database, creating associations between the source, destination, and secondary information, receiving a request to analyze information stored and associated in the database, determining whether the database comprises information necessary to perform the requested analysis, identifying if additional information is needed to perform the requested analysis, updating the secondary information associations to include the additional information if needed to perform the requested analysis, and analyzing the information stored and associated in the database based on the received analysis request or query.
FILED Friday, September 30, 2016
APPL NO 15/281615
ART UNIT 3688 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 21/602 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0838 (20130101)
G06Q 10/08355 (20130101) Original (OR) Class
G06Q 2220/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113750 Dixon et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Robert E. Dixon (Haymarket, Virginia);  Kelley A. Sullivan (Washington, District of Columbia)
ABSTRACT System and method for providing electronic manifesting access for users of a distribution network. A distribution network may provide a user access point, such as by providing application programming interfaces. The access point may provide access the item tracking module upon receipt of valid credentials, such as a user's unique identifier. The access point may receive item information, generate an electronic manifest including the item information and the unique identifier, and allow for tracking the items on the electronic manifest.
FILED Thursday, March 14, 2019
APPL NO 16/353953
ART UNIT 3625 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 7/005 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101)
G06Q 30/0635 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11113851 Chang et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-S&T)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Ching-wei Chang (Oakland, California);  Lambertus Hesselink (San Jose, California)
ABSTRACT A method for correcting image data from a differential phase contrast imaging system is provided. Data comprising distorted data due to spatial variation is obtained. The data is corrected by correcting the distorted data.
FILED Wednesday, July 17, 2019
APPL NO 16/514730
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 11/006 (20130101)
G06T 11/008 (20130101) Original (OR) Class
G06T 2211/421 (20130101)
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11114183 McNamara et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Joseph McNamara (Egg Harbor City, New Jersey);  Alexander DeMasi (Mays Landing, New Jersey);  Michael Brogden (Galloway, New Jersey);  Ronald Krauss (Galloway, New Jersey)
ABSTRACT In one embodiment, a method for identifying and forming a simulant includes identifying a composition, identifying a plurality of ingredients, the simulant being a combination of the ingredients, identifying for evaluation one or more metrics of the simulant, determining proportions of each of the ingredients by optimizing a quadratic function based on the one or more metrics of the simulant, rendering, via a GUI, a 3D plot that depicts the metrics and a target point specified by the target values of the composition, when the target point is contained within a convex set defined by the identified ingredients, outputting the determined proportions of each of the identified ingredients and, otherwise, receiving user input to adjust the convex set by user selecting and moving the data points of the 3D plot to modify the metrics of the simulant to produce a new 3D plot, and identifying alternative ingredients and/or alternative proportions.
FILED Monday, March 22, 2021
APPL NO 17/208759
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 30/00 (20200101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/30 (20190201) Original (OR) Class
G16C 20/50 (20190201)
G16C 20/80 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11110183 Mohapatra et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) Shyam S. Mohapatra (Lutz, Florida);  Subhra Mohapatra (Lutz, Florida);  Eleni Markousta (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Shyam S. Mohapatra (Lutz, Florida);  Subhra Mohapatra (Lutz, Florida);  Eleni Markousta (Tampa, Florida)
ABSTRACT A multifunctional dendrimer nanoparticle and method of treating diseases of the posterior segment of the eye is presented. The functionalized polyamidoamine (PAMAM) dendrimer effectively delivers drugs and/or genes to the posterior eye, thereby providing for the effective, non-invasive, and topical treatment of diseased in the posterior eye. The multifunctional dendrimer nanoparticle has shRNA-encoding DNA and small molecule drug encapsulated cyclodextrin complexed to the outer surface of the dendrimer for delivery to the posterior segment of the eye.
FILED Monday, August 05, 2019
APPL NO 16/531734
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 31/4439 (20130101)
A61K 31/7088 (20130101)
A61K 47/60 (20170801)
A61K 47/61 (20170801)
A61K 47/62 (20170801)
A61K 47/549 (20170801)
A61K 47/6935 (20170801) Original (OR) Class
A61K 47/6951 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/122 (20130101)
C12N 2310/351 (20130101)
C12N 2310/531 (20130101)
C12N 2320/31 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11110207 Sakamoto et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Jeffrey S. Sakamoto (Ann Arbor, Michigan);  Dena Shahriari (Woodland Hills, California);  Mark H. Tuszynski (La Jolla, California);  Wendy Campana (La Jolla, California);  Yacov Koffler (San Diego, California)
ABSTRACT Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ≤about 100 μm that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.
FILED Tuesday, August 20, 2019
APPL NO 16/545855
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101) Original (OR) Class
A61L 27/58 (20130101)
A61L 2300/252 (20130101)
A61L 2300/412 (20130101)
A61L 2430/32 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
C08L 89/00 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11111239 Barbosa
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) GB006, INC. (San Diego, California)
ASSIGNEE(S) GB006, INC. (San Diego, California)
INVENTOR(S) Antonio J. Barbosa (Ave Maria, Florida)
ABSTRACT The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating β2 integrin-mediated diseases and conditions using the salts and crystalline forms.
FILED Tuesday, November 05, 2019
APPL NO 16/675097
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Acyclic or Carbocyclic Compounds
C07C 215/08 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11111527 Kanavarioti
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Anastassia Kanavarioti (El Dorado Hills, California)
ASSIGNEE(S)
INVENTOR(S) Anastassia Kanavarioti (El Dorado Hills, California)
ABSTRACT Provided for herein is a method for detecting the presence of a nucleic acid target molecule in a biological sample. In certain aspects, the method comprises contacting a test sample that comprises (i) a biological sample comprising a nucleic acid target molecule and (ii) an osmylated single-stranded oligonucleotide probe comprising at least one pyrimidine residue covalently bonded to a substituted or unsubstituted Osmium tetroxide (OsO4)-2,2′-bypyridine group (OsBp group).
FILED Monday, October 05, 2020
APPL NO 17/063245
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6832 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11112241 Rzhanov
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S) University of New Hampshire (Durham, New Hampshire)
ASSIGNEE(S) UNIVERSITY OF NEW HAMPSHIRE (Durham, New Hampshire)
INVENTOR(S) Yuri Rzhanov (Nottingham, New Hampshire)
ABSTRACT An apparatus and method are presented comprising one or more sensors or cameras configured to rotate about a central motor. In some examples, the motor is configured to travel at a constant linear speed while the one or more cameras face downward and collect a set of images in a predetermined region of interest. The apparatus and method are configured for image acquisition with non-sequential image overlap. The apparatus and method are configured to eliminate gaps in image detection for fault-proof collection of imagery for an underwater survey. In some examples, long baseline (LBL) is utilized for mapping detected images to a location. In some examples, ultra-short baseline (USBL) is utilized for mapping detected images to a location. The apparatus and method are configured to utilize a simultaneous localization and mapping (SLAM) approach.
FILED Tuesday, October 29, 2019
APPL NO 16/667390
ART UNIT 2483 — Recording and Compression
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 11/025 (20130101) Original (OR) Class
G01C 13/00 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/89 (20130101)

Pictorial Communication, e.g Television
H04N 5/2253 (20130101)
H04N 5/23299 (20180801)
H04N 7/181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 11113919 Rich et al.
FUNDED BY
Department of the Treasury (TREASURY)
Bureau of Engraving and Printing (BEP)
APPLICANT(S) Wavefront Technology, Inc. (Paramount, California)
ASSIGNEE(S) WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
INVENTOR(S) Christopher Chapman Rich (Rancho Palos Verdes, California);  Joel Mikael Petersen (Valley Village, California);  Roger Winston Phillips (Santa Rosa, California);  John Michael Tamkin (Pasadena, California)
ABSTRACT An optical device includes an array of lenses and a plurality of first and second segments disposed under the array of lenses. At a first viewing angle, the array of lenses presents a first image for viewing without presenting the second image for viewing, and at a second viewing angle different from the first viewing angle, the array of lenses presents for viewing the second image without presenting the first image for viewing. In some examples, individual ones of the first and second segments can comprise specular reflecting, transparent, diffusely reflecting, and/or diffusely transmissive features. In some examples, individual ones of the first and second segments can comprise transparent and non-transparent regions. Some examples can incorporate more than one region producing an optical effect.
FILED Monday, August 20, 2018
APPL NO 16/105759
ART UNIT 2872 — Optics
CURRENT CPC
Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/00 (20141001)
B42D 25/21 (20141001)
B42D 25/23 (20141001)
B42D 25/24 (20141001)
B42D 25/28 (20141001)
B42D 25/29 (20141001)
B42D 25/30 (20141001)
B42D 25/45 (20141001)
B42D 25/324 (20141001)
B42D 25/328 (20141001)
B42D 25/342 (20141001)
B42D 25/351 (20141001)
B42D 25/355 (20141001)
B42D 25/373 (20141001)
B42D 25/378 (20141001)
B42D 25/425 (20141001)
B42D 25/435 (20141001)
B42D 25/445 (20141001)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/55 (20130101)
G01N 21/4738 (20130101)
G01N 2201/063 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/005 (20130101)
G02B 3/0056 (20130101)
G02B 5/0278 (20130101)
G02B 5/0284 (20130101)

Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing
G07D 7/128 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11111804 Behling et al.
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Weston Behling (Norwalk, Connecticut);  Jason Leroux (Kensington, Connecticut);  Robert B. Fuller (Colchester, Connecticut);  Steven D. Roberts (Moodus, Connecticut)
ABSTRACT Integrally bladed rotors (IBRs) are described. The IBRs include a central hub, an outer rim defining an outer circumference of the central hub, the outer rim defining a plurality of platforms, a plurality of circumferentially distributed blades, wherein a blade extends from each of the plurality of platforms, a rotor slot arranged between two adjacent blades, wherein the rotor slot is defined by a cut within the outer rim, and a rotor slot insert installed within the rotor slot, the rotor slot insert sized and shaped to fit within the rotor slot and prevent air leakage from a first side of the central hub to a second side of the central hub through the rotor slot during operation of the integrally bladed rotor.
FILED Monday, March 11, 2019
APPL NO 16/298027
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/30 (20130101)
F01D 11/008 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2240/24 (20130101)
F05D 2240/55 (20130101)
F05D 2300/20 (20130101)
F05D 2300/171 (20130101)
F05D 2300/172 (20130101)
F05D 2300/173 (20130101)
F05D 2300/174 (20130101)
F05D 2300/1723 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11113597 Martin et al.
FUNDED BY
APPLICANT(S) HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Charles E. Martin (Santa Monica, California);  Nicholas A. Ketz (Madison, Wisconsin);  Praveen K. Pilly (Tarzana, California);  Soheil Kolouri (Agoura Hills, California);  Michael D. Howard (Westlake Village, California);  Nigel D. Stepp (Santa Monica, California)
ABSTRACT A method for retraining an artificial neural network trained on data from an old task includes training the artificial neural network on data from a new task different than the old task, calculating a drift, utilizing Sliced Wasserstein Distance, in activation distributions of a series of hidden layer nodes during the training of the artificial neural network with the new task, calculating a number of additional nodes to add to at least one hidden layer based on the drift in the activation distributions, resetting connection weights between input layer nodes, hidden layer nodes, and output layer nodes to values before the training of the artificial neural network on the data from the new task, adding the additional nodes to the at least one hidden layer, and training the artificial neural network on data from the new task.
FILED Thursday, September 05, 2019
APPL NO 16/561735
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6215 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/0472 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 07, 2021.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

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